TNF receptor-associated factor

Query:  443 LNICEKKDKCVYSLENITGII-ENLQKYAFRSMEIEEQHKTDFEFLKTNLKSRDQELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            L  CE  +K   + ENI  ++   +++ A  +     QH+ D + ++  L S+ Q+L    R I     ++  LE+ V  L  E  T   +                       FIWKI+ F+ K+ E       ++FS AFYT   GYK+CL I  NG     G +L  FF +MKGP D  L WP   +V L ++DQ             +   ++   SF +P  + N   G   F    ++   N+ +R+D+I ++  ++
Sbjct:  269 LQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEA-LSSKVQQL---ERSIGLKDLAMADLEQKV--LEMEASTYDGV-----------------------FIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ-----NNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497          

Query:  758 YAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            + +L+T  +    IWKI  +  ++ E       S++S+ FYT   GYK+C  +  NG     G +L  FF IM+G YD  LPWP K +V L ++DQ S           +   +    SF KP  E N   G   F++   L      +++D+I ++  ++ 
Sbjct:  381 FQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGS----SRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDT 537          

Query:  758 YAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            + +L+T  +    IWKI  +  ++ E       S++S+ FYT   GYK+C  +  NG     G +L  FF IM+G YD  LPWP K +V L ++DQ S           +   +    SF KP  E N   G   F++   L      +++D+I ++  ++ 
Sbjct:  381 FQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGS----SRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDT 537          

Query:  758 YAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            + +L+T  +    IWKI  +  ++ E       S++S+ FYT   GYK+C  +  NG     G +L  FF IM+G YD  LPWP K +V L ++DQ S           +   +    SF KP  E N   G   F++   L      +++D+I ++  ++ 
Sbjct:  323 FQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGS----SRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDT 479          

Query:  758 YAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            + +L+T  +    IWKI  +  ++ E       S++S+ FYT   GYK+C  +  NG     G +L  FF IM+G YD  LPWP K +V L ++DQ S           +   +    SF KP  E N   G   F++   L      +++D+I ++  ++ 
Sbjct:  406 FQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGS----SRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDT 562          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHS--FSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
             IWKI+   ++  E +   D ++FS  F +H  GYK+       G     GK +  +  ++KG +D  L WP    + +S++DQ    + +          ++  +    ++P+ ERN   G   F S   L +L N +++D I ++  ++
Sbjct:  265 LIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCS---LAILQNYVKDDKIYVQIDVD 412          

Query:  845 SVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIV 1027
            S++S+ FY+H  GYK+     P G      +Y   F C+MKG +DD L WP + +V  SI+
Sbjct:  182 SIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSIL 242          

Query:  773 TKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNE-GIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            T   +WKI  +S K  E        + S  FYT   GYKL   +  NG       ++  +  ++ G YD  L WP    +  ++ +Q +           S   +    +F +P  E ++ G G   FIS + LH     ++ D++ LR  ++
Sbjct:  321 TGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGA--QSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLH-SRPFIKGDTVFLRVKVD 470          

Query:  773 TKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNE-GIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            T   +WKI  +S K  E        + S  FYT   GYKL   +  NG       ++  +  ++ G YD  L WP    +  ++ +Q +           S   +    +F +P  E ++ G G   FIS + LH     ++ D++ LR  ++
Sbjct:  330 TGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGA--QSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLH-SRPFIKGDTVFLRVKVD 479          

Query:  569 EFLKTNLKSRDQELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQ 1033
            +++ +   + D E+ N++ ++ E +E    L+ A++  ++    L+  +      +++     +        IW+I  +S K+LE     D  + S  F     GY L L I  NG   + G+ +     ++ G YD  L WP +L+  + I DQ
Sbjct:  272 DYVTSKQATLDYEVKNVKNIVCETEERCDKLDRALHQTMQNISDLETQMAMQQRIASVQNIRGH-------LIWRIKDYS-KKLEESKQYDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQ 418          

Query:  569 EFLKTNLKSRDQELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQ 1033
            +++ +   + D E+ N++ ++ E +E    L+ A++  ++    L+  +      +++     +        IW+I  +S K+LE     D  + S  F     GY L L I  NG   + G+ +     ++ G YD  L WP +L+  + I DQ
Sbjct:  250 DYVTSKQATLDYEVKNVKNIVCETEERCDKLDRALHQTMQNISDLETQMAMQQRIASVQNIRGH-------LIWRIKDYS-KKLEESKQYDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQ 396          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQ 1033
             IW+I  +S K+LE     D  + S  F     GY L L I  NG   + G+ +     ++ G YD  L WP +L+  + I DQ
Sbjct:  257 LIWRIKDYS-KKLEESKQYDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQ 339          

Query:  467 KCVYSLENITGII-ENLQKYAFRSMEIEEQHKTDFEFLKTNLKSRDQELVNMRRLISEN---QESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            K V +LENI  ++ + +++ A     I  QH+ D E ++ NL ++ ++L   R L + +    ES Q+L E   C  +                               FIWKI  FS ++ +       ++FS AFY+   GYK+CL +  NG     G +L  FF +MKG YD  L WP   +V L ++DQ             +   ++   SF +P  E N   G   F    +L   ++ LR+D+I ++  ++
Sbjct:  308 KKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIE-NLSNKVRQL--ERTLTTRDLQLAESEQSLRELQFCTYD-----------------------------GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ-----NNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 528          

Query:  467 KCVYSLENITGII-ENLQKYAFRSMEIEEQHKTDFEFLKTNLKSRDQELVNMRRLISEN---QESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            K V +LENI  ++ + +++ A     I  QH+ D E ++ NL ++ ++L   R L + +    ES Q+L E   C  +                               FIWKI  FS ++ +       ++FS AFY+   GYK+CL +  NG     G +L  FF +MKG YD  L WP   +V L ++DQ             +   ++   SF +P  E N   G   F    +L   ++ LR+D+I ++  ++
Sbjct:  308 KKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIE-NLSNKVRQL--ERTLTTRDLQLAESEQSLRELQFCTYD-----------------------------GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ-----NNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 528          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            FIW+I+ F++K+ +       ++FS AFYT   GYK+CL I  NG     G +L  FF +M+G  D  L WP   +V L ++DQ             +   ++   SF +P  E N   G   F    +L   N+ +R+D+I ++  ++
Sbjct:  134 FIWRISDFTKKRQDAIAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGMSDALLKWPFNQKVTLMLLDQ-----SNREHIIDAFRPDITSSSFQRPVSEMNIASGCPLFCPLAKLEGKNSYIRDDTIFIKAIVD 277          

Query:  467 KCVYSLENITGII-ENLQKYAFRSMEIEEQHKTDFEFLKTNLKSRDQELVNMRRLISEN---QESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            K V +LENI  ++ + +++ A     I  QH+ D E ++ NL ++ ++L   R L + +    ES Q+L E   C  +                               FIWKI  FS ++ +       ++FS AFY+   GYK+CL +  NG     G +L  FF +MKG YD  L WP   +V L ++DQ             +   ++   SF +P  E N   G   F    +L   ++ LR+D+I ++  ++
Sbjct:  321 KKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIE-NLSNKVRQL--ERTLTTRDLQLAESEQSLRELQFCTYD-----------------------------GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ-----NNREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 541          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            F+WKI+ FS+K+ +       ++FS AFYT   GYK+CL I  NG     G +L  FF +M+G  D  L WP   +V L ++DQ             +   ++   SF +P  + N   G   F    +L   N+ +R+D+I ++  ++
Sbjct:  128 FVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ-----NNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVD 271          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPN-GANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERN-EGIGDNEFISFKELHLL--NNILRNDSILLRCSINA 1231
            FIW+IN+F+      E +    + S+ FYT   GYKLCL ++    + Q    Y+  F   M+G YD  LPWP++  + LSI+DQ      +  +       E+L  +F +P   RN +G G   +++F  L  L     ++ND++L+RCS+  
Sbjct:  389 FIWRINNFNSLLKNQEEERPVVIHSQGFYTGKPGYKLCLRLHLQLPSAQRCANYISLFVHTMQGEYDSLLPWPLQGTIRLSILDQSEGVAMQDQEEVMDTKPELL--AFQRPTVARNPKGFG---YVTFMHLQALKQRQYVKNDTLLVRCSVTT 537          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNE------GIGDNEFISFKELHLLNNILRNDSILLRCSINAP 1234
             IWKI+ +S K  E +   +   FS  FYTH  GYKL +    NG     G YL  +  ++ G YD+ L WP    V  S++DQ      K      +   +    +F KP   RN       G G  +FIS +++    N +R+++I LR S+  P
Sbjct:  310 LIWKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQSDPSLSKPQHITETFNPDPNWKNFQKPTGSRNSLDESTLGFGYPKFISHEDIR-KRNYVRDNAIFLRASVEIP 465          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNI-LRNDSILLRCSINA 1231
            F+WKI+  + K  +       S++S AFYT   GYK+CL I  NG     G ++  FF +MKG YD  LPWP K +V   +VD              +   ++   SF +P  + N   G   F    +L+   +  +R +++ +RC I+ 
Sbjct:  232 FLWKISDLTNKSHDAVTGRAISLYSPAFYTAKYGYKVCLRIYLNGDGAGKGTHVSLFFTVMKGEYDALLPWPFKHKVTFVLVDH-----NNRDSVFDAFRPDVTSASFQRPINDMNVASGCPLFCPIAKLNSPKHAYIRENTLYIRCIIDT 377          

Query:  758 YAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            + +L+T  +    IWKI  +  ++ E       S++S+ FYT   GYK+C  +  NG     G +L  FF IM+G YD  LPWP K +V L ++DQ             +   +    SF KP  E N   G   F++   L      +++D+I ++  ++ 
Sbjct:  399 FQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQ----GPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDT 555          

Query:  758 YAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            + +L+T  +    IWKI  +  ++ E       S++S+ FYT   GYK+C  +  NG     G +L  FF IM+G YD  LPWP K +V L ++DQ             +   +    SF KP  E N   G   F++   L      +++D+I ++  ++ 
Sbjct:  374 FQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQ----GPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDT 530          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            FIWKI+ F+ K+ E       ++FS AFYT   GYK+CL +  NG     G +L  FF +MKGP D  L WP   +V L ++D              +   ++   SF +P  + N   G   F    ++   N+ +R+D+I ++  ++
Sbjct:  361 FIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH-----NNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 504          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            FIWKI+ F+ K+ E       ++FS AFYT   GYK+CL +  NG     G +L  FF +MKGP D  L WP   +V L ++D              +   ++   SF +P  + N   G   F    ++   N+ +R+D+I ++  ++
Sbjct:  354 FIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH-----NNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497          

Query:  758 YAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            + +L+T  +    IWKI  +  ++ E       S++S+ FYT   GYK+C  +  NG     G +L  FF IM+G YD  LPWP K +V L ++DQ S           +   +    SF KP  E N   G   F++   L      +++D+I ++  ++ 
Sbjct:  405 FQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGS----SRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDT 561          

Query:  758 YAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            + +L+T  +    IWKI  +  ++ E       S++S+ FYT   GYK+C  +  NG     G +L  FF IM+G YD  LPWP K +V L ++DQ S           +   +    SF KP  E N   G   F++   L      +++D+I ++  ++ 
Sbjct:  380 FQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGS----SRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDT 536          

Query:  758 YAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            + +L+T  +    IWKI  +  ++ E       S++S+ FYT   GYK+C  +  NG     G +L  FF IM+G YD  LPWP K +V L ++DQ S           +   +    SF KP  E N   G   F++   L      +++D+I ++  ++ 
Sbjct:  380 FQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGS----SRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDT 536          

Query:  443 LNICEKKDKCVYSLENITGII-ENLQKYAFRSMEIEEQHKTDFEFLKTNLKSRDQELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            L  CE  +K   + ENI  ++   +++ A  +     QH+ D + ++  L S+ Q+L    R I     ++  LE+ V  L  E  T   +                       FIWKI+ F+ K+ E       ++FS AFYT   GYK+CL I  NG     G +L  FF +MKGP D  L WP   +V L ++DQ             +   ++   SF +P  + N   G   F    ++   N+ +R+D+I ++  ++
Sbjct:  269 LQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEA-LSSKVQQL---ERSIGLKDLAMADLEQKV--LEMEASTYDGV-----------------------FIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ-----NNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPN-GANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERN-EGIGDNEFISFKELHLL--NNILRNDSILLRCSIN 1228
            FIW+I  FS  Q   E +    + S  FYT D GYKLCL ++    + Q    Y+  F   M+G YD  LPWP++  + LSI+DQ      +          ++L  +F +P   RN +G G   +++F  L+ L     ++ND++L+RCS+N
Sbjct:  387 FIWRIKGFSGLQKSQEEEKPVVIHSPGFYTGDPGYKLCLRLHLQLPSAQRCANYISLFVHTMQGDYDSLLPWPLQGTIRLSILDQSESTARQDQVEVMDTKPDLL--AFQRPTAPRNPKGFG---YVTFMHLNTLKQRQYVKNDTLLVRCSVN 534          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            FIWKI+ F+ K+ E       ++FS AFYT   GYK+CL +  NG     G +L  FF +MKGP D  L WP   +V L ++D              +   ++   SF +P  + N   G   F    ++   N+ +R+D+I ++  ++
Sbjct:  354 FIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH-----NNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPN-GANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERN-EGIGDNEFISFKELHLL--NNILRNDSILLRCSINA 1231
            FIW+IN+F+      E +    + S+ FYT   GYKLCL ++    + Q    Y+  F   M+G YD  LPWP++  + LSI+DQ      +  +       E+L  +F +P   RN +G G   +++F  L  L     ++ND++L+RCS+  
Sbjct:  389 FIWRINNFNSLLKNQEEERPVVIHSQGFYTGKPGYKLCLRLHLQLPSAQRCANYISLFVHTMQGEYDSLLPWPLQGTIRLSILDQSEGVAMQDQEEVMDTKPELL--AFQRPTVARNPKGFG---YVTFMHLQALKQRQYVKNDTLLVRCSVTT 537          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPN-GANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERN-EGIGDNEFISFKELHLL--NNILRNDSILLRCSIN 1228
            FIWKI  FS  Q   E +    + S  FYT   GYKLCL ++    + Q    Y+  F   M+G YD  LPWP+   + LSI+DQ      +  +       ++L  +F +P  +RN +G G   +++F  L+ L     ++ND++ +RC++N
Sbjct:  387 FIWKIKGFSGLQKTQEEEKPVVIHSPGFYTGKPGYKLCLRLHLQLPSAQRCANYISLFVHTMQGEYDSLLPWPLHGTIRLSILDQSEGAIIQDQEEVMDTKPDLL--AFQRPTTQRNPKGFG---YVTFMHLNTLKQRQYVKNDTLFVRCAVN 534          

Query:  176 LLCTCCRKLIIDPRKASCGCRFCENCSQKPSKTDNK------CPNFHLASKLHSNIVTFNFQVDLETSLKVAHLEVFCPNNECQFICKLRFLADHLNICEKKDKCVYSLENITGIIE----NLQKYAFRSM--EIEEQHKTDFEFLKTNLKSRDQELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYA---ILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            LLC  C  L+++P++A CG R+C  C +   +   +      C N     + HS+    N  +D +         + CPN +C++   L+   +HL  C   +  + + +N T I E    N +K A  S+   I      + E +   +++ +  + ++RR +++   +++TL+   +C  +  E LK    + N+      +   A          IWK+ +FS+   + +     S+FS AF TH  GY+L + + P+G     G +L  F  + KGPYDD LPWP + +V  S++D       +      +   +    SF +P  + N   G   F +  E   + N L++D++ L+ +++
Sbjct:    9 LLCQACGFLLVNPQQAECGHRYCRRCVKGLFRDSERIVSCLTCKNVLHLKEFHSDKAAENDALDTQ---------IACPNFDCRWTGTLKSYQEHL--CHP-EVPIGTTKNATLIPEDQNENKEKEAHWSVTAPIMGGPSLNIEAVHLRMEALELMVASLRRQLNQQVSNVKTLQ---HCCSQYEELLKISQETQNSPHGTKGSGPSAQELASTDGTLIWKVENFSKLLKDAKSGKRHSIFSLAFATHPFGYRLYVRLYPDGDGVGKGSHLSVFLALAKGPYDDILPWPFRQKVTFSLLDPT----RRKSPLTETFLPDPHSTSFQQPHQKLNVASGSPLFANHVE---IPNYLKDDTLFLKIAVD 352          

Query:  152 PIQPIDNV-LLCTCCRKLIIDPRKASCGCRFCENCSQKPSKTDNKCPNFHLASKLHSNIVTFNFQVDLETSLKVAHLEVFCPNNECQFICKLRFLADHLNICEK----KDKCVYSLENITGIIENLQKYAFRSMEIEEQHKTDFEFLKTNLKSRDQELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVD 1030
            P+ P+ N  LLC  C  L+I P++A CG R+C  C ++  +  +K     L       +    F  D          EV CPN  C +   L+   DH+   E       +   +L +   + E    +  ++   E       E +   ++S +  +V++RR ++     +++L+    C  +  + LK       +    +   S  I      +WK+ +FS+   +       SV+S  F TH  GY LC+ + P+G     G +L  F  + +GPYDD LPWP + +V   ++D
Sbjct:    2 PVDPVANAGLLCQACGFLLIAPQQAECGHRYCLGCVKRLFRDTDKV----LCHACRQELSPRQFHSDKAAENDALATEVACPNFGCAWSGTLKSYQDHVCPPEAPFGTAKESALALRDQEAVEEKGLTWTSKNSS-EGGSSLTTEAVVLRVESLELMVVSLRRQLNNQVAMVKSLQR---CCSQYEKLLKTTPEGHRSPKGSIPTSSELISTNGMLVWKVENFSKLLRDATSGKKRSVYSPVFATHPFGYHLCVRMYPDGDGIGKGSHLSLFLAVARGPYDDVLPWPFQQKVTFVLLD 291          

Query:  608 LVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXX----------XXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            +  +R+L  +N+     +EE +N L+EEN+ LK  +  +           +    +   +  I +   ++WKI  FS+ +       + ++ SEAFYT D GYK+C+ I P G     G +L  FF IMKG YDD LPWP K +V+++I D  S    K+     +   +     + +P+ E N   G  +FISF E   L N L+ D++ ++ ++ A
Sbjct:  242 VTELRKLEKQNKH----MEERMNILIEENQLLKATLEVMKLDLPKNSGSISRDTSLKRANKTIFRNGKYMWKIKSFSKLRENAMRGKNPTILSEAFYTSDFGYKMCMKIYPCGDGVGKGTHLSIFFVIMKGDYDDILPWPFKNKVIITIFDDFS----KSTNLSDTFKPDPKSICYQRPEEEYNIASGSPKFISFSE---LKNFLKKDTLYIQINVIA 448          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHS--FSKPKFERNEGIGDNEFISFKELHLLNNILRN 1198
            FIW+I+ + +K  E +     ++FS  FY+H NGY++CL I PNG  +  GKYL  F CI +G YD  L WP  L + L ++DQ    D +       + + +  ++    +P  ERN+  G   F+  ++LHL + ++ N
Sbjct:  145 FIWRIDGYGKKVEEAQQGRKATLFSSPFYSHRNGYRVCLSICPNGEQRVRGKYLSVFICICRGEYDALLSWPFSLPITLKLLDQNINPDLRQDHQVTIRPNPIPSNNAYLKRPSSERNQCFGSPRFLELEQLHLRDYVVDN 285          

Query:  179 LCTCCRKLIIDPRKASCGCRFCENCSQKP-SKTDNKCPNFHLASKLHSNIVTFNFQVDLETS---------LKVAHLEVFCPNNECQFICKLRFLADHLNICEKKDKCVYSLENITGIIENLQKYAFRSMEIEEQHKTDFEFLKTNLKSRDQELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            LC+ C+ ++  P +A CG R+C  C +K  S    KC     AS +   I      + LETS          +V  L   C N+ C +   ++    H  +C +     + L    G  + + +    +     QH+ D E ++T L ++ ++L    R I     ++  +EE +  +  E  T   +                       FIWKI  F+ K+ E       ++FS AFYT   GYK+CL +  NG     G +L  FF +MKGP D  L WP   +V L ++DQ             +   ++   SF +P  E N   G   F     +   N+ +R+D+I ++  ++
Sbjct:   33 LCSDCKNILRRPFQAQCGHRYCSYCLKKIISAGPQKC-----ASCIQEGIYEEGISI-LETSSAFPDNAARREVESLPAVCINSGCTWKGTIKEYEAHDEVCPE-----FPL-TCEGCGKKVPREKVPTEAYSRQHRLDQEKIET-LSNKVRQL---ERSIGLKDLAMAEMEEKIRNM--EASTYDGV-----------------------FIWKITEFARKRQEAITGRSPAIFSPAFYTSKYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ-----NNREHIIDAFRPDVTSSSFQRPVTEMNIASGCPLFCPVSVMEAKNSYVRDDAIFIKAIVD 346          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            F+WKI+ FS+K+ +       ++FS AFYT   GYK+CL I  NG     G +L  FF +M+G  D  L WP   +V L ++DQ             +   ++   SF +P  + N   G   F    +L   N+ +R+D+I ++  ++
Sbjct:  312 FVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ-----NNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVD 455          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            F+WKI+ FS ++ +       ++FS AFY+   GYK+CL +  NG     G +L  FF +M+G YD  L WP   +V L ++DQ             +   ++   SF +P  E N   G   F    +L   ++ LR+D+I ++  ++
Sbjct:  384 FVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQ-----NNREHIIDAFRPDISSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 527          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            F+WKI+ FS+K+ +       ++FS AFYT   GYK+CL I  NG     G +L  FF +M+G  D  L WP   +V L ++DQ             +   ++   SF +P  + N   G   F    +L   N+ +R+D+I ++  ++
Sbjct:  425 FVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ-----NNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVD 568          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNE------GIGDNEFISFKELHLLNNILRNDSILLRCSINAP 1234
             IWK+N +S K  E +   +   FS  FYTH  GYKL +    NG     G +L  +  ++ G YD+ L WP   +V  SI+DQ      K      +   +    +F KP   RN       G G  +FIS  E+    N +R+++I L+ SI  P
Sbjct:  310 LIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPSSSRNSLDESTLGFGYPKFISHDEIR-KRNYIRDNAIFLKASIEIP 465          

Query:  785 IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            IWKI  +  ++ E       S++S+ FYT   GYK+C  +  NG     G +L  FF +M+G YD  LPWP K +V L ++DQ             +   +    SF +P  E N   G   F++   L      +++D+I ++ +++
Sbjct:    7 IWKIRDYKRRKAEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQ----GPARKHLGDAFKPDPNSSSFRRPTGEMNIASGCPLFVAQTVLE-NGTYIKDDTIFIKVTVD 149          

Query:  377 LEVFCPNNECQFICKLRFLADHLNICEKKDKCVYSLE----NITGIIENLQKYAFRSMEIEEQHKTDFEFLKTNLKS--RDQELVNMRRLISENQESIQTLEEAVN--CLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            LE+ C   +C        + DH N+ E   + V  LE    + + +  +       ++E+  QH    + L    ++  RD +   +RR ++  +E ++ LE A+      EE   +     ++++           +L+T  +    +WKI  ++ ++ E       S++S+ FYT   GYK+C     NG     G +L  FF +M+G YD  L WP +  V LS++DQ +           + T +    SF +P  + N   G   F+S   L   ++ L +D++ +R  ++
Sbjct:  130 LELQCARLQCS-------IEDHTNMSEMLTQRVAQLEQDLSHWSTLTGSNNTRLGSTLEMLTQHNEQLQSLHVAQRAPQRDADTAALRRDMATLRERLRALEAALGNPGPCEERCHMHEQRLTMHDGLLDTAERRLQVLETAGYSGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGA----ARRHLSDTFTPDPASGSFRRPDGDMNVASGCPLFVSHVALE-GSSYLVDDTVFVRVVVD 413          

Query:  758 YAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            + +L+T  +    +WKI  ++ ++ +       S++S+ FYT   GY++C     NG     G +L  FF +M+G YD  LPWP +  V L+++DQ +       +   +   +    SF +P  + N   G   F+S   L    + L++D+I ++  ++
Sbjct:  315 FQVLETASYNGKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGA----ARRQLSDTFKPDPASSSFRRPTSDMNIASGCPLFVSHVALE-SASYLQDDTIFIKVVVD 470          

Query:  782 FIWKINHFSE---KQLEFEFDTDG-------SVFSEAFYTHDNGYKLCLGIN-------PNGANQ----YLGK--YLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQ-----HSFSKPKFERN-EGIGDNEFISFKELHLLNNILRNDSILLRCSI 1225
            F W++  FS      L   F +DG        + S  FYT   GY+LCL +        P GA        G+  +L  F  +++G YD  LPWP K  + +S+VDQ                +EM+       +F +P   RN +G G   F+    LH   + LR+D +++RC +
Sbjct:  395 FTWRVERFSRLLPGGLASGFASDGMHPDAPAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAGRQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCE--------RDSVHVTEMMDADPQLSAFQRPSVHRNPKGFGYMNFMDINTLH-HRSYLRDDCLVVRCEV 562          

Query:  761 AILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQ 1033
            AI     F+WKI+ F+E+  E +     S++S  FYTH  GYKLC  + PNG       YL  F  +M+G YD  LPWP +  + ++++DQ
Sbjct:  375 AISYDGTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQ 465          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            +IWKI+ ++ +  E       S++S  FY    GYK C  + PNG     G +L  FF +M+G +D  LPWP + +V   ++DQ  +          +   +    SF +P    N   G   FIS   L      +R+D++ ++ +++
Sbjct:  380 YIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQDRV-----HDIGDTFRPDPTSSSFKRPTSNMNIASGCPLFISHTNLQ-TRAYVRDDTMFIKIAVD 522          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERN-EGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            FIWK+++F + +         ++ S  FYT   GYK+CL +N NG +  LG+++  F  +M+G +D  L WP    + LSI+DQ    D +    +       L  +F +P   RN +G G  EF    +L      ++N+SIL+R  I+
Sbjct:  334 FIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGLGEHVSLFIHMMQGDWDGILEWPFIGRITLSILDQSDQIDSRRPISETLVAKPNLL-AFQRPTSPRNHKGYGYVEFCPIDQL-TEGQYIKNNSILVRIQIS 481          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHS--FSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
             IW+I  ++ K  E +     ++FS  F T  +GY+LC  +  NG  +  G ++  F  ++KG +D  L WP    V   ++DQ      +       K +    +     +P+ E+N   G  +F   +E+ +  N ++ D+I L+ S++
Sbjct:  304 LIWRIEDYTRKMKEAKAGNTDTLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFISVLKGAFDALLKWPFDYRVTFVLLDQNDDPAQRKHIRFSIKPNPCADNEPFLGRPRLEKNASFGGAKFAKHEEI-VSRNYIKEDTIFLKISVD 453          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINAP 1234
             +WKI + + K+ E       S +S  F+T  +GYK+C  I  NG       ++  FF IM+G +D  L WP + +V L ++DQ +++           +S     SF +P+ E N   G   F S ++L   +  +R+D++ L+  ++ P
Sbjct:  335 LLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQDNVEHVIDAFRPDPSSS-----SFQRPRAEMNIASGCPLFCSHEQL-TQHAYIRDDTMFLKIIVDKP 479          

Query:  182 CTCCRKLIIDPRKASCGCRFCENCSQKPSKTDNKCPNFHLASKLHSNIVTFNFQVDLETSLKVAHLEVFCPN--NECQFICKLRFLADHLNICE----------------KKD-------KCVYSLENITGIIEN------LQKY------AF--------------RSMEIEEQHKTDFEFLKTNLKSRDQ---ELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPF----IWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINA 1231
            C  CR ++  PR+  CG RFC +C          CPN    + +        F+ D+    ++  L+V+C +  N CQ    L+ + DH+N+C                 +K+       KC Y  E+     +N      LQK+      AF              RS ++   H      L+  L+S  Q   E+ ++R  +   +  +  LE+     LE        + S++      ++  + +L+T  +    IWKI  +  ++ +       S++S+ FYT   GYK+C  +  NG     G +L  FF +M+G YD  LPWP K +V L ++DQ             +   +    SF +P  E N   G   F+S   L      +++D+I ++ +++ 
Sbjct:   48 CEACRLVLCQPRQTECGHRFCYSCIND----ILSCPNPVCPADMEPLFKDKIFR-DVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCPLGKCKERMMRKEIPEHLAWKCKYR-ESTCEFCKNKMPLTELQKHKETVCPAFPVSCPNHCTSSSLPRSEKLMSSHTEKLLELELELRSLRQLRDEMESLRGTLDTVRTRLSALEQGGRASLETQLNRHDDMLSVHEIRLADMDLRFQVLETASYNGTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQ----GPSRKHLGDAFKPDPSSSSFRRPVAEMNIASGCPLFVSQSVLE-SGTYIKDDTIFIKVTVDT 444          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            FIW+I+ F++K+ +       ++FS AFYT   GYK+CL I  NG     G +L  FF +M+G  D  L WP   +V L ++DQ             +   ++   SF +P  E N   G   F    +L   N+ +R+D+I ++  ++
Sbjct:  449 FIWRISDFAKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGLSDALLKWPFNQKVTLMLLDQ-----SNREHIIDAFRPDVTSSSFQRPVSEMNIASGCPLFCPLSKLDAKNSYIRDDTIFIKAIVD 592          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            FIWKI+ F++K+ +       ++FS AFYT   GYK+CL I  NG     G +L  FF +M+G  D  L WP   +V L ++DQ             +   ++   SF +P  + N   G   F    +L   N+ +R+++I ++  ++
Sbjct:  422 FIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ-----NNREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDETIFIKAIVD 565          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            F+WKI  FS ++ E       ++FS AFY+   GYK+CL +  NG     G +L  FF +M+  YD  L WP   +V L ++DQ             +   ++   SF +P  E N   G   F    +L   +  LR+D+I ++  ++
Sbjct:  369 FVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQ-----NNREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVD 512          

Query:  782 FIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            F+WKI  FS ++ E       ++FS AFY+   GYK+CL +  NG     G +L  FF +M+  YD  L WP   +V L ++DQ             +   ++   SF +P  E N   G   F    +L   +  LR+D+I ++  ++
Sbjct:  376 FVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQ-----NNREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVD 519          

Query:   89 MSVTTAQLSAIWGLLKKYEIRPIQPIDNVLLCTCCRKLIIDPRKASCGCRFCENCSQKPSKTDNKCPNFHLASKLHSNIVTFNFQVDLETSLKVAHLEVFCPNNECQFICKLRFLADHLNICEKKDKCVYSLENITGIIENLQKYAFRSMEIEEQHKTDFEFLKTNLKSRDQELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINAP 1234
            MSVTTAQLSAIWGLLKKYEIRPIQPIDNVLLCTCCRKLIIDPRKASCGCRFCENCS+KPSK DNKCPNFHLASKLHSNIVTFNFQVDLETSLKVAHLEVFCPNNECQFICKLRFLADHLNICEKKDKCVYSLENITGIIENLQKYAFRSMEIEEQHKTDFEFLKTNLKSRDQELVN RRLISENQESIQTLEEAVNCLLEENETLKRLINSLNNSSALVVNHSYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLF FFCIMKGPYDDNLPWPMKLEVVLSIVDQISLKD+KTFKFKYSKTSEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINAP
Sbjct:    1 MSVTTAQLSAIWGLLKKYEIRPIQPIDNVLLCTCCRKLIIDPRKASCGCRFCENCSRKPSKIDNKCPNFHLASKLHSNIVTFNFQVDLETSLKVAHLEVFCPNNECQFICKLRFLADHLNICEKKDKCVYSLENITGIIENLQKYAFRSMEIEEQHKTDFEFLKTNLKSRDQELVNTRRLISENQESIQTLEEAVNCLLEENETLKRLINSLNNSSALVVNHSYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFMFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLKDYKTFKFKYSKTSEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSINAP 382          

Query:  110 LSAIWGLLKKYEIRPIQPIDNVLLCTCCRKLIIDPRKASCGCRFCENCSQK-PSKTDNKCPNFHLASKLHSNIVTFNFQVDLETSLKVAHLEVFCPNNECQFICKLRFLADHLNICEKKDKCVYSLENITGIIENLQ-KYAFRSM--------EIEEQHKTDFEFLKTNLKSRDQELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            +S +    K + I     +D  LLC  C++++I+  +ASCGC+ C NC ++   K  + CP        +      +F+ +   + KV  + V CPN  C + C+L  + DH+  C    +   +  N+    ENL      R +        E E+Q K + + LK  L++ +QEL   ++ +  N+  +++L+E V  L +EN+ LKRLI+    S   +    Y I K KPF+W++  FS KQ + + D    +FS+ FY++ NGYKLCLG+ PNG + + GK+LF FFCI+    D NL WPM+ +V LSI+D  +LKD K +KF Y   S+  +HSFSKP+ +RN+GIGDNEFISFKEL  + NI +ND+IL++C I+
Sbjct:    1 MSHVQPTQKPFNIISSTQVDEKLLCMLCQRILINADRASCGCKLCLNCCKEFMEKNRDHCPTCGFLKIENGK----DFEANHSVNSKVWRIVVKCPNIFCDYECELGAMNDHVEECFLLQQSKGATNNVDKTFENLDLANIVRGLNNKISILAENEKQGKIEMDELKQKLENCNQELNYFKKQLDTNELFLESLQETVENLKDENKDLKRLIDKQGLSVITLTPT-YDIHKPKPFLWRVTEFSRKQQDAKLDRKTIIFSDPFYSNYNGYKLCLGMYPNGVSNFEGKFLFVFFCILPSQNDGNLSWPMRHQVALSILDHNTLKDHKVYKFAYFSESKSCEHSFSKPESDRNDGIGDNEFISFKELSSMKNIFKNDTILIKCVID 378          

Query:   95 VTTAQLSAIWGLLKKYEIRPIQPIDNVLLCTCCRKLIIDPRKASCGCRFCENCSQKPSKTDNK-CPNFHLASKLHSNIVTFNFQVDLETSLKVAHLEVFCPNNECQFICKLRFLADHLNICEKK-----------DKCVYSLENITGIIENLQKYAFRSMEIEEQHK---TDFEFLKTNLKSRDQELVNMRRLISENQESIQTLEEAVNCLLEENETLKRLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            ++ ++L  +W ++K +    ++ I N +LC  C+ ++I+   A CGCRFC +C  +     NK C       +L    +  N  VD   ++K+  L+V CP   C+ + +LR + DH  IC+ +           DKC  S E +  +   ++       E+  ++K    D   LK+N + R              QE I  L+   +   EEN  +K+L     N  +     +Y       FIWKI  FSEK    +   + S++SE F TH NGYK+CL ++P+G+    G +L   FC+MKG +D+ L WP +  V+ S+++Q +     +   K        +   S+PK +RN G+G+  FI+ KE+    ++  ND I ++C ++
Sbjct:    1 MSGSKLENVWQVVKNHNYDYVKEISNEMLCLLCKNVLINAHFAPCGCRFCLSCISEFLGGQNKMCLGNTEECQLEMLNLAENIFVDHPMNVKILKLKVKCPQRFCESVEELRKMEDHSRICKYRSVPSPFSNFGSDKCSKSEEKVDQMNNEIKLMKTHIFELRAENKLLRNDINKLKSNEEKR--------------QEEIAVLQCKCD---EENLKIKQL---NVNMISFNTKVTYG-----EFIWKIEKFSEKITHAKNGINHSIYSEPFITHRNGYKMCLELHPDGSGTGTGTHLSMCFCLMKGDFDEILEWPFRHSVIFSLLNQRTHLPHVSLIAKCRDFPNYKE--LSQPK-DRNYGMGNQLFITQKEISSNPDLANNDQIFIKCFVD 365          

Query:   95 VTTAQLSAIWGLLKKYEIRPIQPIDNVLLCTCCRKLIIDPRKASCGCRFCENC-SQKPSKTDNKCPNFHLASKLHSNIVTFN--FQVDLETSLKVAHLEVFCPNNECQFICKLRFLADHLNICEKKDKCVYS-------LENITGIIENLQKYAFRSMEIEEQH----KTDFEFLKTNLKSRDQELVN-----------MRRLISENQESIQTLEEAVNCLLEEN-------ETLK--------------------------RLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            +  A+   IW LL +YE      + +  LC  C  ++ +P ++ CGCRFC  C     +  +  CP    +      ++ FN     D   S K++ ++V CP   C +  +L+ + +H  I   K+ C Y+         ++  I+E+L    +   ++  +     K +   L   LK   QEL N           +  L    +  IQ L E ++   EEN        TLK                          ++I+        +   S   +   PF WKI  F  K L+        V S  FY+H NGYKLC+ I+P+G    LG Y+  F  +MKG +D NL WPMKL++ + +VDQIS   F   KF YS      +H +S+P   +N GIG+++FI    L   + I   DSI+L+C + 
Sbjct:    1 MANAKYERIWKLLDEYEFAYDSLLSDEFLCVICNSILKNPYQSPCGCRFCMECIVDYLNDKETHCPGS--SEDCKDQLINFNGDLHADYVISRKISQVKVKCPKALCDYRSELQNIGNH--ISSHKESCPYTNIGCQYPSAHMGLIVEHLHDQIYEHGKLVTESFANLKNEVASLTLALKHSKQELENKDNLLIDLENRLNELQGTREIKIQELTETLDKCKEENVQLSSELRTLKSVSEVFSSNQKPKKGEKVQDEDLEKYKVISKNITQLIPMKPISTDHISYAPFEWKIRDF--KALKASTVIPTYVISRPFYSHVNGYKLCMTIHPSGTGIGLGSYISVFIHVMKGEFDSNLAWPMKLDLRICLVDQISDSYFVDKKFDYSSAILRNKHKYSRPFCVKNIGIGESQFIQLNALFNNSRIYLEDSIILKCFVG 430          

Query:   95 VTTAQLSAIWGLLKKYEIRPIQPIDNVLLCTCCRKLIIDPRKASCGCRFCENC-SQKPSKTDNKCPNFHLASKLHSNIVTFN--FQVDLETSLKVAHLEVFCPNNECQFICKLRFLADHLNICEKKDKCVYS-------LENITGIIENLQKYAFRSMEIEEQH----KTDFEFLKTNLKSRDQELVN-----------MRRLISENQESIQTLEEAVNCLLEEN-------ETLK--------------------------RLIXXXXXXXXXXXXXXYAILKTKPFIWKINHFSEKQLEFEFDTDGSVFSEAFYTHDNGYKLCLGINPNGANQYLGKYLFTFFCIMKGPYDDNLPWPMKLEVVLSIVDQISLXXXXXXXXXXXXXXEMLQHSFSKPKFERNEGIGDNEFISFKELHLLNNILRNDSILLRCSIN 1228
            +  A+   IW LL +YE      + +  LC  C  ++ +P ++ CGCRFC  C     +  +  CP    +      ++ FN     D   S K++ ++V CP   C +  +L+ + +H  I   K+ C Y+         ++  I+E+L    +   ++  +     K +   L   LK   QEL N           +  L    +  IQ L E ++   EEN        TLK                          ++I+        +   S   +   PF WKI  F  K L+        V S  FY+H NGYKLC+ I+P+G    LG Y+  F  +MKG +D NL WPMKL++ + +VDQIS   F   KF YS      +H +S+P   +N GIG+++FI    L   + I   DSI+L+C + 
Sbjct:   27 MANAKYERIWKLLDEYEFAYDSLLSDEFLCVICNSILKNPYQSPCGCRFCMECIVDYLNDKETHCPGS--SEDCKDQLINFNGDLHADYVISRKISQVKVKCPKALCDYRSELQNIGNH--ISSHKESCPYTNIGCQYPSAHMGLIVEHLHDQIYEHGKLVTESFANLKNEVASLTLALKHSKQELENKDNLLIDLENRLNELQGTREIKIQELTETLDKCKEENVQLSSELRTLKSVSEVFSSNQKPKKGEKVQDEDLEKYKVISKNITQLIPMKPISTDHISYAPFEWKIRDF--KALKASTVIPTYVISRPFYSHVNGYKLCMTIHPSGTGIGLGSYISVFIHVMKGEFDSNLAWPMKLDLRICLVDQISDSYFVDKKFDYSSAILRNKHKYSRPFCVKNIGIGESQFIQLNALFNNSRIYLEDSIILKCFVG 456