Fibroblast growth factor receptor 2

Overview
NameFibroblast growth factor receptor 2
Smed IDSMED30024551
Length (bp)3004
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Fibroblast growth factor receptor 2 (SMED30024551) t-SNE clustered cells

Violin plots show distribution of expression levels for Fibroblast growth factor receptor 2 (SMED30024551) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Fibroblast growth factor receptor 2 (SMED30024551) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Fibroblast growth factor receptor 2 (SMED30024551) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30024551

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30024551h1SMcG0020600 Contig37827uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30024551h1SMcG0020600 Contig37827newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
parapharyngeal regionSMED30024551h1SMcG0020600 dd_Smed_v4_12998_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pigment cellSMED30024551h1SMcG0020600 SMED30024551smed_20140614PMID:22884275
Lapan et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Human
Match: FGFR2 (fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:HGNC:3689])

HSP 1 Score: 275.018 bits (702), Expect = 1.890e-80
Identity = 139/315 (44.13%), Postives = 203/315 (64.44%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNN 2745
            ++Y LP +  W F RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L  +  L    T  +E  DL+ 
Sbjct:  236 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTL----TTNEEYLDLSQ 546          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Human
Match: FGFR2 (fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:HGNC:3689])

HSP 1 Score: 275.018 bits (702), Expect = 1.641e-79
Identity = 134/294 (45.58%), Postives = 195/294 (66.33%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W F RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L
Sbjct:  376 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 669          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Human
Match: FGFR2 (fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:HGNC:3689])

HSP 1 Score: 274.633 bits (701), Expect = 1.852e-79
Identity = 134/294 (45.58%), Postives = 195/294 (66.33%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W F RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L
Sbjct:  373 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 666          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Human
Match: FGFR2 (fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:HGNC:3689])

HSP 1 Score: 275.404 bits (703), Expect = 1.896e-79
Identity = 137/308 (44.48%), Postives = 200/308 (64.94%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKK 2724
            ++Y LP +  W F RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L  +  L  +   KK
Sbjct:  375 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEEKK 682          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Human
Match: FGFR2 (fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:HGNC:3689])

HSP 1 Score: 275.404 bits (703), Expect = 2.099e-79
Identity = 139/314 (44.27%), Postives = 203/314 (64.65%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN 2742
            ++Y LP +  W F RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L  +  L    T  +E  DL+
Sbjct:  352 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTL----TTNEEYLDLS 661          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 254.603 bits (649), Expect = 1.560e-70
Identity = 151/391 (38.62%), Postives = 220/391 (56.27%), Query Frame = 1
Query: 1657 KKPFVISYRHVDLSGSKSDSPTDGLPNTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQT-----------------RAVDITNIPVVP-ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVE--HYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN---NSQFYS 2760
            KK  V+S R ++     SD               +       +R ++  +N   ++Y + S+  W   R  L +   +GEGAFG V+ A  K  TEN+  I VA+K L  S  ++++I+L+ E+E  K+IG H +++ L G C   G  Y+V+EL K+GNLRDFLR  R +                  +A D  +I ++P +T   L++F+ ++A+GM +L+S+ IIHRDLAARNVLV     +KISDFGL+R V    YYRK  +GRLPIKWMA E L   +YT++SDVWS+G++LWEI T+G TPYPTI    ++  L+ G R E P L   E+Y LM + W +   +R SF  +V+ L  M      +TM  E  + +   N QF+S
Sbjct:  517 KKRVVVSKRPMNEDNENSDDEPSPYQIQIIETPITKKEAARKQRKRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYKE-TENNE-IAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDWM------LTMTNETIEGSQEFNDQFFS 899          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 254.603 bits (649), Expect = 1.560e-70
Identity = 151/391 (38.62%), Postives = 220/391 (56.27%), Query Frame = 1
Query: 1657 KKPFVISYRHVDLSGSKSDSPTDGLPNTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQT-----------------RAVDITNIPVVP-ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVE--HYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN---NSQFYS 2760
            KK  V+S R ++     SD               +       +R ++  +N   ++Y + S+  W   R  L +   +GEGAFG V+ A  K  TEN+  I VA+K L  S  ++++I+L+ E+E  K+IG H +++ L G C   G  Y+V+EL K+GNLRDFLR  R +                  +A D  +I ++P +T   L++F+ ++A+GM +L+S+ IIHRDLAARNVLV     +KISDFGL+R V    YYRK  +GRLPIKWMA E L   +YT++SDVWS+G++LWEI T+G TPYPTI    ++  L+ G R E P L   E+Y LM + W +   +R SF  +V+ L  M      +TM  E  + +   N QF+S
Sbjct:  517 KKRVVVSKRPMNEDNENSDDEPSPYQIQIIETPITKKEAARKQRKRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYKE-TENNE-IAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDWM------LTMTNETIEGSQEFNDQFFS 899          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 254.603 bits (649), Expect = 1.560e-70
Identity = 151/391 (38.62%), Postives = 220/391 (56.27%), Query Frame = 1
Query: 1657 KKPFVISYRHVDLSGSKSDSPTDGLPNTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQT-----------------RAVDITNIPVVP-ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVE--HYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN---NSQFYS 2760
            KK  V+S R ++     SD               +       +R ++  +N   ++Y + S+  W   R  L +   +GEGAFG V+ A  K  TEN+  I VA+K L  S  ++++I+L+ E+E  K+IG H +++ L G C   G  Y+V+EL K+GNLRDFLR  R +                  +A D  +I ++P +T   L++F+ ++A+GM +L+S+ IIHRDLAARNVLV     +KISDFGL+R V    YYRK  +GRLPIKWMA E L   +YT++SDVWS+G++LWEI T+G TPYPTI    ++  L+ G R E P L   E+Y LM + W +   +R SF  +V+ L  M      +TM  E  + +   N QF+S
Sbjct:  517 KKRVVVSKRPMNEDNENSDDEPSPYQIQIIETPITKKEAARKQRKRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYKE-TENNE-IAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDWM------LTMTNETIEGSQEFNDQFFS 899          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 254.603 bits (649), Expect = 1.560e-70
Identity = 151/391 (38.62%), Postives = 220/391 (56.27%), Query Frame = 1
Query: 1657 KKPFVISYRHVDLSGSKSDSPTDGLPNTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQT-----------------RAVDITNIPVVP-ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVE--HYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN---NSQFYS 2760
            KK  V+S R ++     SD               +       +R ++  +N   ++Y + S+  W   R  L +   +GEGAFG V+ A  K  TEN+  I VA+K L  S  ++++I+L+ E+E  K+IG H +++ L G C   G  Y+V+EL K+GNLRDFLR  R +                  +A D  +I ++P +T   L++F+ ++A+GM +L+S+ IIHRDLAARNVLV     +KISDFGL+R V    YYRK  +GRLPIKWMA E L   +YT++SDVWS+G++LWEI T+G TPYPTI    ++  L+ G R E P L   E+Y LM + W +   +R SF  +V+ L  M      +TM  E  + +   N QF+S
Sbjct:  517 KKRVVVSKRPMNEDNENSDDEPSPYQIQIIETPITKKEAARKQRKRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYKE-TENNE-IAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDWM------LTMTNETIEGSQEFNDQFFS 899          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Celegans
Match: egl-15 (Myoblast growth factor receptor egl-15 [Source:UniProtKB/Swiss-Prot;Acc:Q10656])

HSP 1 Score: 254.218 bits (648), Expect = 1.600e-70
Identity = 151/391 (38.62%), Postives = 220/391 (56.27%), Query Frame = 1
Query: 1657 KKPFVISYRHVDLSGSKSDSPTDGLPNTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQT-----------------RAVDITNIPVVP-ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVE--HYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN---NSQFYS 2760
            KK  V+S R ++     SD               +       +R ++  +N   ++Y + S+  W   R  L +   +GEGAFG V+ A  K  TEN+  I VA+K L  S  ++++I+L+ E+E  K+IG H +++ L G C   G  Y+V+EL K+GNLRDFLR  R +                  +A D  +I ++P +T   L++F+ ++A+GM +L+S+ IIHRDLAARNVLV     +KISDFGL+R V    YYRK  +GRLPIKWMA E L   +YT++SDVWS+G++LWEI T+G TPYPTI    ++  L+ G R E P L   E+Y LM + W +   +R SF  +V+ L  M      +TM  E  + +   N QF+S
Sbjct:  517 KKRVVVSKRPMNEDNENSDDEPSPYQIQIIETPITKKEAARKQRKRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYKE-TENNE-IAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDWM------LTMTNETIEGSQEFNDQFFS 899          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Fly
Match: htl (gene:FBgn0010389 transcript:FBtr0083550)

HSP 1 Score: 253.832 bits (647), Expect = 7.246e-72
Identity = 142/306 (46.41%), Postives = 190/306 (62.09%), Query Frame = 1
Query: 1798 ILQNDAH----TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVD------ITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQS-DGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVE 2676
            +LQN        +Y  P +  W   R  L++G+ +GEGAFG V  A V +         VA+K +     D+D+ +L++E+E+MKIIGRH +II+L G C  NG  Y+++E A +GNL+DFL   R   R  D        + P   IT  DL++F+ +IA GM+YL+SR  IHRDLAARNVLV     +KI+DFGL R ++   YYRK T+GRLPIKWMAPE L ++ Y  KSDVWS+GI+LWEI T GQ PYPTI S + ++  L +G R EKP   S  +Y LM   W+ +  DR  FTE+VE
Sbjct:  388 VLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVNNAI-------VAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVE 686          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Fly
Match: htl (gene:FBgn0010389 transcript:FBtr0083549)

HSP 1 Score: 253.832 bits (647), Expect = 7.246e-72
Identity = 142/306 (46.41%), Postives = 190/306 (62.09%), Query Frame = 1
Query: 1798 ILQNDAH----TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVD------ITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQS-DGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVE 2676
            +LQN        +Y  P +  W   R  L++G+ +GEGAFG V  A V +         VA+K +     D+D+ +L++E+E+MKIIGRH +II+L G C  NG  Y+++E A +GNL+DFL   R   R  D        + P   IT  DL++F+ +IA GM+YL+SR  IHRDLAARNVLV     +KI+DFGL R ++   YYRK T+GRLPIKWMAPE L ++ Y  KSDVWS+GI+LWEI T GQ PYPTI S + ++  L +G R EKP   S  +Y LM   W+ +  DR  FTE+VE
Sbjct:  388 VLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVNNAI-------VAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVE 686          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Fly
Match: htl (gene:FBgn0010389 transcript:FBtr0083548)

HSP 1 Score: 253.832 bits (647), Expect = 7.246e-72
Identity = 142/306 (46.41%), Postives = 190/306 (62.09%), Query Frame = 1
Query: 1798 ILQNDAH----TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVD------ITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQS-DGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVE 2676
            +LQN        +Y  P +  W   R  L++G+ +GEGAFG V  A V +         VA+K +     D+D+ +L++E+E+MKIIGRH +II+L G C  NG  Y+++E A +GNL+DFL   R   R  D        + P   IT  DL++F+ +IA GM+YL+SR  IHRDLAARNVLV     +KI+DFGL R ++   YYRK T+GRLPIKWMAPE L ++ Y  KSDVWS+GI+LWEI T GQ PYPTI S + ++  L +G R EKP   S  +Y LM   W+ +  DR  FTE+VE
Sbjct:  388 VLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVNNAI-------VAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVE 686          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Fly
Match: btl (gene:FBgn0285896 transcript:FBtr0100676)

HSP 1 Score: 233.032 bits (593), Expect = 4.834e-63
Identity = 129/302 (42.72%), Postives = 182/302 (60.26%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIE--VAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRR--IQTRAVD----ITNIPVVP---ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVE--HYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQS-DGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
             +Y  P +  W   R  L +GS +GEGAFG V  A  +    +    E  VA+K +     D D+ +L++E+E+MK+IG+H +II+L G C   G  ++++E A +GNL+DFL+  R     R  D    + + P++    +   +L +F+ +IA GMEYL+SR  IHRDLAARNVLV     MKI+DFGL R ++   YYRK T+GRLPIKWMAPE L ++ Y  +SDVWS+G++LWEI T G  PYP I S + ++  L  G R EKP   S  +Y +M   W+ +   R +F ELVE  
Sbjct:  695 NEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESF 996          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Fly
Match: btl (gene:FBgn0285896 transcript:FBtr0075778)

HSP 1 Score: 233.032 bits (593), Expect = 4.834e-63
Identity = 129/302 (42.72%), Postives = 182/302 (60.26%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIE--VAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRR--IQTRAVD----ITNIPVVP---ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVE--HYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQS-DGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
             +Y  P +  W   R  L +GS +GEGAFG V  A  +    +    E  VA+K +     D D+ +L++E+E+MK+IG+H +II+L G C   G  ++++E A +GNL+DFL+  R     R  D    + + P++    +   +L +F+ +IA GMEYL+SR  IHRDLAARNVLV     MKI+DFGL R ++   YYRK T+GRLPIKWMAPE L ++ Y  +SDVWS+G++LWEI T G  PYP I S + ++  L  G R EKP   S  +Y +M   W+ +   R +F ELVE  
Sbjct:  695 NEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESF 996          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Zebrafish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 272.707 bits (696), Expect = 2.594e-82
Identity = 141/310 (45.48%), Postives = 204/310 (65.81%), Query Frame = 1
Query: 1831 LPSNIGWIFSRDSLIIGSKIGEGAFG--IVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN 2742
            LPS+  W F+R  L +G  +GEG FG  ++  A+     + + P+ VA+K L     D+D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + D   IP   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWS+G++LWEIFT+G +PYP I  + + + L+ G R +KP   + E+Y +M   W+  P  R +F +LVE   H ++L  S+T   E  DL+
Sbjct:   29 LPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVED--HDRVL--SMTSTDEYLDLS 334          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Zebrafish
Match: fgfr1a (fibroblast growth factor receptor 1a [Source:NCBI gene;Acc:30705])

HSP 1 Score: 277.715 bits (709), Expect = 1.560e-80
Identity = 159/415 (38.31%), Postives = 241/415 (58.07%), Query Frame = 1
Query: 1564 HRNSYEESLLQQKHSDSSSNIPFSNKLSKYFKKPFVISYRHVDLSGSKSDSPTDGLP--------NTATNQATSNSLTVEPRR------PQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAP--IEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNS 2748
            HR   +  L   + +   S++ F  K+     +P +   +H++++GS+     DGLP          +++   S  + V P R      P +       ++Y LP +  W   RD L++G  +GEG FG V  A      +       +VA+K L +   ++D+ +LI E+EMMKIIG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR        +   +PV  +++ DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + H  YY+KTT+GRLP+KWMAPE L DRIYT +SDVWSFG++LWEIFT+G +PYP +  + + + L+ G R ++P   + E+Y +M   W+  P  R +F +LVE L        S+T  +E  DL+ S
Sbjct:  242 HRPILQAGLPANRTAVVGSDVEFECKVFSD-PQPHIQWLKHIEVNGSRYGP--DGLPYVRALKVSVDSSSSMHSGGMLVRPSRLSSSGSPML----SGVSEYELPQDPRWEVQRDRLVLGKPLGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDLDRT----LSMTSNQEYLDLSVS 645          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Zebrafish
Match: fgfr1a (fibroblast growth factor receptor 1a [Source:NCBI gene;Acc:30705])

HSP 1 Score: 277.715 bits (709), Expect = 1.560e-80
Identity = 159/415 (38.31%), Postives = 241/415 (58.07%), Query Frame = 1
Query: 1564 HRNSYEESLLQQKHSDSSSNIPFSNKLSKYFKKPFVISYRHVDLSGSKSDSPTDGLP--------NTATNQATSNSLTVEPRR------PQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAP--IEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNS 2748
            HR   +  L   + +   S++ F  K+     +P +   +H++++GS+     DGLP          +++   S  + V P R      P +       ++Y LP +  W   RD L++G  +GEG FG V  A      +       +VA+K L +   ++D+ +LI E+EMMKIIG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR        +   +PV  +++ DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + H  YY+KTT+GRLP+KWMAPE L DRIYT +SDVWSFG++LWEIFT+G +PYP +  + + + L+ G R ++P   + E+Y +M   W+  P  R +F +LVE L        S+T  +E  DL+ S
Sbjct:  242 HRPILQAGLPANRTAVVGSDVEFECKVFSD-PQPHIQWLKHIEVNGSRYGP--DGLPYVRALKVSVDSSSSMHSGGMLVRPSRLSSSGSPML----SGVSEYELPQDPRWEVQRDRLVLGKPLGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDLDRT----LSMTSNQEYLDLSVS 645          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Zebrafish
Match: fgfr1b (fibroblast growth factor receptor 1b [Source:ZFIN;Acc:ZDB-GENE-060503-14])

HSP 1 Score: 276.559 bits (706), Expect = 8.897e-80
Identity = 138/314 (43.95%), Postives = 204/314 (64.97%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAP--IEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL-------AHMQLLECSVTMK 2721
            ++Y LP +  W  SR+ L++G  +GEG FG V         ++      +VA+K L +   ++D+ +LI E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR        +   +P+  +++ DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R V H  YY+KTT+GRLP+KWMAPE L DRIYT +SDVWSFG++LWEIFT+G +PYP +  + + + LR G R +KP   + E+Y +M   W+  P  R +F +LVE L       ++ + LE SV ++
Sbjct:  380 SEYELPQDPCWEVSRERLVLGKPLGEGCFGQVVMGEAIGLDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARRPHGMEYCYNPDPLPIESMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLREGHRMDKPSACTQELYLMMKDCWHAVPTQRPTFKQLVEDLDRTLSLISNQEYLELSVPLE 693          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Zebrafish
Match: fgfr1a (fibroblast growth factor receptor 1a [Source:NCBI gene;Acc:30705])

HSP 1 Score: 277.33 bits (708), Expect = 1.763e-79
Identity = 140/316 (44.30%), Postives = 203/316 (64.24%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAP--IEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNS 2748
            ++Y LP +  W   RD L++G  +GEG FG V  A      +       +VA+K L +   ++D+ +LI E+EMMKIIG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR        +   +PV  +++ DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + H  YY+KTT+GRLP+KWMAPE L DRIYT +SDVWSFG++LWEIFT+G +PYP +  + + + L+ G R ++P   + E+Y +M   W+  P  R +F +LVE L        S+T  +E  DL+ S
Sbjct:  447 SEYELPQDPRWEVQRDRLVLGKPLGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDLDRT----LSMTSNQEYLDLSVS 758          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Xenopus
Match: fgfr4 (fibroblast growth factor receptor 4 [Source:NCBI gene;Acc:549077])

HSP 1 Score: 276.944 bits (707), Expect = 9.486e-80
Identity = 137/290 (47.24%), Postives = 191/290 (65.86%), Query Frame = 1
Query: 1831 LPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTEN--SAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQT--RAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            LP +  W F RD L++G  +GEG FG V  A      +     P+ VA+K L  +  D+D+ +LI E+E+MK+IG+H++II+L G C   G  ++++E A  GNLR+FLR RR  T   A DIT +P   ++  DL+  + ++A GMEYL S+  IHRDLAARNVLV +   MKI+DFGL R V    YY+KT++GRLP+KWMAPE L DR+YT +SD+WSFG++ WEIFT+G +PYP I  + + + LR G R +KP   + E+Y LM   W+  P  R +F +LVE+L
Sbjct:  383 LPLDAKWEFPRDRLVLGKPLGEGCFGQVVRAEGYGIDKERPEKPVTVAVKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEGPLFVIVEYASKGNLREFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIHRDLAARNVLVAEDNVMKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDIWSFGVLTWEIFTLGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRECWHAVPSQRPTFKQLVEQL 672          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Xenopus
Match: c1orf84 (chromosome 1 open reading frame 84 [Source:Xenbase;Acc:XB-GENE-6041758])

HSP 1 Score: 277.33 bits (708), Expect = 1.224e-79
Identity = 142/314 (45.22%), Postives = 204/314 (64.97%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTEN--SAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRI--QTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN 2742
            ++Y LP +  W FSRD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMKIIG+H++II+L GAC   G  Y+++E A  GNLR +LR RR      + D+T +P   +T  DL+  + +IA GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L  +     ++T  +E  DL+
Sbjct:  403 SEYELPHDPLWEFSRDKLTLGKPLGEGCFGQVVMAEALGIDKDRPKESVTVAVKMLKDDATEKDLADLVSEMEMMKIIGKHKNIINLLGACTQGGTLYVIVEYAAKGNLRQYLRARRPLEMEYSFDVTRVPDEQMTFKDLVSCTYQIARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDVNNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYMMMRDCWHAIPSHRPTFKQLVEDLDRI----LTLTTNEEYLDLS 712          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Xenopus
Match: c1orf84 (chromosome 1 open reading frame 84 [Source:Xenbase;Acc:XB-GENE-6041758])

HSP 1 Score: 277.715 bits (709), Expect = 1.697e-79
Identity = 138/294 (46.94%), Postives = 195/294 (66.33%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRI--QTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W FSRD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMKIIG+H++II+L GAC   G  Y+++E A  GNLR +LR RR      + D+T +P   +T  DL+  + +IA GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L
Sbjct:  435 SEYELPHDPLWEFSRDKLTLGKPLGEGCFGQVVMAEALGIDKDRPKESVTVAVKMLKDDATEKDLADLVSEMEMMKIIGKHKNIINLLGACTQGGTLYVIVEYAAKGNLRQYLRARRPLEMEYSFDVTRVPDEQMTFKDLVSCTYQIARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDVNNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYMMMRDCWHAIPSHRPTFKQLVEDL 728          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Xenopus
Match: tirap (toll-interleukin 1 receptor (TIR) domain containing adaptor protein [Source:Xenbase;Acc:XB-GENE-920263])

HSP 1 Score: 273.478 bits (698), Expect = 2.639e-79
Identity = 135/294 (45.92%), Postives = 195/294 (66.33%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTEN--SAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W  +RD LI+G  +GEG FG V  A      +   +   +VA+K L +   ++D+ +LI E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR        + T  P   ++  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + H  YY+KTT+GRLP+KWMAPE L DRIYT +SDVWSFG++LWEIFT+G +PYP +  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L
Sbjct:  298 SEYELPEDPRWEVARDRLILGKPLGEGCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPTCAPDQLLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPMEELFKLLKEGHRMDKPTTCTNELYMMMKDCWHAMPSQRPTFNQLVEDL 591          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Xenopus
Match: c1orf84 (chromosome 1 open reading frame 84 [Source:Xenbase;Acc:XB-GENE-6041758])

HSP 1 Score: 277.33 bits (708), Expect = 4.101e-79
Identity = 138/294 (46.94%), Postives = 195/294 (66.33%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRI--QTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W FSRD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMKIIG+H++II+L GAC   G  Y+++E A  GNLR +LR RR      + D+T +P   +T  DL+  + +IA GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L
Sbjct:  475 SEYELPHDPLWEFSRDKLTLGKPLGEGCFGQVVMAEALGIDKDRPKESVTVAVKMLKDDATEKDLADLVSEMEMMKIIGKHKNIINLLGACTQGGTLYVIVEYAAKGNLRQYLRARRPLEMEYSFDVTRVPDEQMTFKDLVSCTYQIARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDVNNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYMMMRDCWHAIPSHRPTFKQLVEDL 768          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Mouse
Match: Fgfr2 (fibroblast growth factor receptor 2 [Source:MGI Symbol;Acc:MGI:95523])

HSP 1 Score: 275.018 bits (702), Expect = 2.067e-80
Identity = 134/294 (45.58%), Postives = 195/294 (66.33%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W F RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L
Sbjct:  252 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 545          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Mouse
Match: Fgfr2 (fibroblast growth factor receptor 2 [Source:MGI Symbol;Acc:MGI:95523])

HSP 1 Score: 274.633 bits (701), Expect = 3.083e-80
Identity = 134/294 (45.58%), Postives = 195/294 (66.33%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W F RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L
Sbjct:  251 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 544          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Mouse
Match: Fgfr2 (fibroblast growth factor receptor 2 [Source:MGI Symbol;Acc:MGI:95523])

HSP 1 Score: 275.018 bits (702), Expect = 1.881e-79
Identity = 134/294 (45.58%), Postives = 195/294 (66.33%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W F RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L
Sbjct:  348 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 641          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Mouse
Match: Fgfr2 (fibroblast growth factor receptor 2 [Source:MGI Symbol;Acc:MGI:95523])

HSP 1 Score: 274.633 bits (701), Expect = 2.447e-79
Identity = 134/294 (45.58%), Postives = 195/294 (66.33%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W F RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L
Sbjct:  352 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 645          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Mouse
Match: Fgfr2 (fibroblast growth factor receptor 2 [Source:MGI Symbol;Acc:MGI:95523])

HSP 1 Score: 274.248 bits (700), Expect = 2.572e-79
Identity = 134/294 (45.58%), Postives = 195/294 (66.33%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W F RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W+  P  R +F +LVE L
Sbjct:  350 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 643          
BLAST of Fibroblast growth factor receptor 2 vs. UniProt/SwissProt
Match: sp|Q8MY85|FGFR2_DUGJA (Fibroblast growth factor receptor 2 OS=Dugesia japonica OX=6161 GN=FGFR2 PE=2 SV=1)

HSP 1 Score: 1014.6 bits (2622), Expect = 0.000e+0
Identity = 511/897 (56.97%), Postives = 645/897 (71.91%), Query Frame = 1
Query:  136 ITVAMTIFTFSYANHCQFKLTADETIYFAPLTPFSLNCRPQFDTDPDLCAHI--QPPYRWTRDNRTV-TPKEGRIKFVESSQTMIVFNGSETDQGQYECSTIDNNH----KQFFVHLTSPSLMQKNLLPNAFPNDPKEEVKGRIYWLPEMLLRQNRQLVIANEGERVELHGAHYVSSEEAAISVFDVHWYYQ---RNATKDIFKGMKTNFNSSCKHLDFLPRNVSGFCHNSQITFEDLTTLNQGFYICAANMILKNGQQDSLNFTYELRINFAQIFDKNTQPEVY--PQITFNQDARACTKDKYEWSCNVTPKKTYVTSIYRIDSHPE--TLLAKSKLKTINITDYKKENGETAAVEDFRETFVVEDFQSCFVQKSLKVKDAGVYECRVFKVDDLFK--ASTYEFKKVMHLTVQDCFEKQDFSVTSWXXXXXXXXXXXXXXXXXXXYRIYKKYSNNYLVKTVIVQLPNKLYVPHDKCFPLIMPEVSIKTTRRHRNSYEESLLQQKHSDSSSNIPFSNKLSKYFKKPFVISYRHVDLSGSKSDSPTDGLPNTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIP--VVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNSQFYSTTNV 2772
            I +   +  ++YA  C F+L+ +ET+ F    P  LNC      D DLC  I  + PY W   N+ +    +G+IK V SSQ MI+FNGS +D+G Y C TI+NN     K F   +  PS+ Q  LL N+FPND +EE+ GRIYWLPEM+L   R +VI N+G   +LH  +YVS  ++ IS FDV WY+    ++  K I       F SSC  LD LPR V+G C++S++   ++   +QGFY   A + +KNG    LNFTYEL+IN A I D +    +   PQI+FN ++R C  D+++W C VTP  +Y  +IY+ +S+P   T+LA+S++  +NI      +G +       + F ++     +   S++ + AGVY CR+    D      + +E + +M LTV+DC     F++  +  +  II    I+   I   R+Y KYSN Y+VKTVIVQ PNKLYVPHD CFPL+MP+++IKT  +H NS E+SLLQQKH  ++SNIPFS K+SKYF+K F+ SYRHVD+S S  DSP   + NT TN+ TSNSLTVE +RPQ+ILQNDA+TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSF+ENSA +EVAIKTLHTSFGD+DVINLIQELEMMKIIGRHRHIISLYGAC+DNG+PYMVIELAK+GNLRDFLR +R Q++  +I N    V  +TV D LRFSIEIAEGMEYLSSR IIHRDLAARNVLVDQY+EMKI+DFGLTR VE+YYRKTTDGRLPIKWMAPECLLDR+YT+KSDVWS+GIVLWEIFTMGQTPYPTIQSDGMHQALRNG+RNEKP LASDEMYRLMLTIWNDDPL+R++F+E+++KL H+QL     + K++  +++++Q YSTT V
Sbjct:    6 IVIVTMLAMWNYAQDCNFELSKNETVQFTSFLPLILNCASISKFDTDLCETINDERPYNWYFQNKKIGNETKGKIKLVSSSQQMIIFNGSASDEGNYMCETINNNKEFISKTFDARMIEPSMTQMELLLNSFPNDHQEEINGRIYWLPEMILNHIRDVVIINQGAESDLHSFYYVSGSDSQISTFDVQWYFHYQPKSEDKTIIDHNIKTFYSSCNDLDLLPRKVNGSCYSSRLYLYNVEIKDQGFYSVEATLRMKNGSSHGLNFTYELKINIANILDPDKTNSILSTPQISFNLNSRVCINDRFDWICKVTPVVSYYVTIYKNNSNPNNITVLAESEVLQMNI------DGNSG------QGFYLKSSTVNYSVNSVQREHAGVYACRIINFKDYSSDHQNRHEPEVLMRLTVKDCVGNSYFTIIWYSISVGIIILVVISFLII---RLYNKYSNGYIVKTVIVQHPNKLYVPHDTCFPLLMPDITIKTIHKHINSSEDSLLQQKHFTNNSNIPFSQKISKYFRKSFIFSYRHVDVSSSNLDSPLGVISNTETNKLTSNSLTVETQRPQLILQNDANTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFSENSASVEVAIKTLHTSFGDQDVINLIQELEMMKIIGRHRHIISLYGACIDNGHPYMVIELAKHGNLRDFLRAQRSQSKVGEIQNSGGLVTRLTVTDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQYVEMKIADFGLTRIVENYYRKTTDGRLPIKWMAPECLLDRVYTVKSDVWSYGIVLWEIFTMGQTPYPTIQSDGMHQALRNGIRNEKPALASDEMYRLMLTIWNDDPLERHTFSEIIDKLTHIQLSNGGSSPKRDYLEISSNQCYSTTIV 887          
BLAST of Fibroblast growth factor receptor 2 vs. UniProt/SwissProt
Match: sp|Q91147|FGFR2_NOTVI (Fibroblast growth factor receptor 2 OS=Notophthalmus viridescens OX=8316 GN=FGFR2 PE=2 SV=1)

HSP 1 Score: 277.33 bits (708), Expect = 2.674e-79
Identity = 143/325 (44.00%), Postives = 206/325 (63.38%), Query Frame = 1
Query: 1804 QNDAH-----TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNN 2745
             ND H     ++Y LP +  W + R+ L +G  +GEG FG V  A      ++       VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LRTRR      + DI  IP   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++E+Y +M   W   P  R +F +LVE L  +     + T  +E  DLNN
Sbjct:  362 NNDTHLLAGVSEYELPEDPKWEYPREKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKDAATVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRTRRPPGMEYSFDINRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTETNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYTMMTDCWRAVPSQRPTFKQLVEDLDRI----LTQTTNEEYLDLNN 682          
BLAST of Fibroblast growth factor receptor 2 vs. UniProt/SwissProt
Match: sp|Q8MY86|FGFR1_DUGJA (Fibroblast growth factor receptor 1 OS=Dugesia japonica OX=6161 GN=FGFR1 PE=2 SV=1)

HSP 1 Score: 280.026 bits (715), Expect = 2.937e-79
Identity = 136/287 (47.39%), Postives = 189/287 (65.85%), Query Frame = 1
Query: 1825 YILPSNIGWIFSRDSL-IIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            Y  P +  W F R+ L I   K+GEGAFG+VY  +       S PI+VA+K +   F D +V + ++E+E+MK IGRH ++I L G C   G   +++ELA YGNLRDF+R +  +          +   T   L  +S++IA GM YL+SR ++HRDL+ARN+LV ++ EMKI+DFGLTR V++YYRK TDG LP+KWMAPE LL++ YT KSDVWS+GI+LWEIFT+G +PY  I  + +   +R G +N KP LA+ E+YRLM   W+    +R +F E+VE L
Sbjct:  535 YEFPCDAKWEFPREKLKITNKKLGEGAFGMVYEGIANDIGNRSNPIKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQKGPLRVIVELAPYGNLRDFVRAKNKKYSKSKKI---IGNFTSSILCTYSLQIARGMTYLASRSVVHRDLSARNILVGEHFEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDSPYSAILPEKVVDLIRKGFQNPKPELANFEIYRLMQHCWSLSSENRPNFFEIVEIL 818          
BLAST of Fibroblast growth factor receptor 2 vs. UniProt/SwissProt
Match: sp|Q91286|FGFR2_PLEWA (Fibroblast growth factor receptor 2 OS=Pleurodeles waltl OX=8319 GN=FGFR2 PE=2 SV=1)

HSP 1 Score: 277.715 bits (709), Expect = 1.370e-78
Identity = 150/364 (41.21%), Postives = 223/364 (61.26%), Query Frame = 1
Query: 1792 QIILQNDAH-----TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSA--PIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNS-QFYSTTNV*ITTSFKRANYYVPSLSPMIVHFLF 2847
            +++   D H     ++Y LP +  W + RD L +G  +GEG FG V  A      ++     + VA+K L     ++D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LRTRR      + DI  IP   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   +KI+DFGL R + +  YY+KTT+GRLP+KWMAPE L DR+YT++SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R  KP   ++E+Y +M   W   P  R +F +LVE L  +     + T  +E  DLNN  + YS +     +S    +  V S  PM ++  F
Sbjct:  447 RLLSNTDTHLLAGVSEYELPEDPKWEYPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKDAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRTRRPPGMEYSFDIFRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTETNVIKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTLQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMVKPGNCTNELYTMMTDCWRAVPSQRPTFKQLVEDLDRI----LTQTTNEEYLDLNNPLEPYSPSYPDTRSSCSFGDDSVFSPDPMSMNLAF 806          
BLAST of Fibroblast growth factor receptor 2 vs. UniProt/SwissProt
Match: sp|Q90Z00|FGR1A_DANRE (Fibroblast growth factor receptor 1-A OS=Danio rerio OX=7955 GN=fgfr1a PE=1 SV=2)

HSP 1 Score: 276.944 bits (707), Expect = 2.096e-78
Identity = 140/316 (44.30%), Postives = 203/316 (64.24%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAP--IEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNS 2748
            ++Y LP +  W   RD L++G  +GEG FG V  A      +       +VA+K L +   ++D+ +LI E+EMMKIIG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR        +   +PV  +++ DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + H  YY+KTT+GRLP+KWMAPE L DRIYT +SDVWSFG++LWEIFT+G +PYP +  + + + L+ G R ++P   + E+Y +M   W+  P  R +F +LVE L        S+T  +E  DL+ S
Sbjct:  448 SEYELPQDPRWEVQRDRLVLGKPLGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDLDRT----LSMTSNQEYLDLSVS 759          
BLAST of Fibroblast growth factor receptor 2 vs. TrEMBL
Match: O76167 (Receptor tyrosine kinase (Fragment) OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 843.958 bits (2179), Expect = 0.000e+0
Identity = 421/681 (61.82%), Postives = 523/681 (76.80%), Query Frame = 1
Query:  754 LDFLPRNVSGFCHNSQITFEDLTTLNQGFYICAANMILKNGQQDSLNFTYELRINFAQIFDKNTQPEVY--PQITFNQDARACTKDKYEWSCNVTPKKTYVTSIYRIDSHPE--TLLAKSKLKTINITDYKKENGETAAVEDFRETFVVEDFQSCFVQKSLKVKDAGVYECRVFKVDDLFK--ASTYEFKKVMHLTVQDCFEKQDFSVTSWXXXXXXXXXXXXXXXXXXXYRIYKKYSNNYLVKTVIVQLPNKLYVPHDKCFPLIMPEVSIKTTRRHRNSYEESLLQQKHSDSSSNIPFSNKLSKYFKKPFVISYRHVDLSGSKSDSPTDGLPNTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIP--VVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNSQFYSTTNV 2772
            LD LPR V+G C++S++   ++   +QGFY   A + +KNG    LNFTYEL+IN A I D +    +   PQI+FN ++R C  D+++W C VTP  +Y  +IY+ +S+P   T+LA+S++  +NI      +G +       + F ++     +   S++ + AGVY CR+    D      + +E + +M LTV+DC     F++  W + +  I    +  F I   R+Y KYSN Y+VKTVIVQ PNKLYVPHD CFPL+MP+++IKT  +H NS E+SLLQQKH  ++SNIPFS K+SKYF+K F+ SYRHVD+S S  DSP   + NT TN+ TSNSLTVE +RPQ+ILQNDA+TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSF+ENSA +EVAIKTLHTSFGD+DVINLIQELEMMKIIGRHRHIISLYGAC+DNG+PYMVIELAK+GNLRDFLR +R Q++  +I N    V  +TV D LRFSIEIAEGMEYLSSR IIHRDLAARNVLVDQY+EMKI+DFGLTR VE+YYRKTTDGRLPIKWMAPECLLDR+YT+KSDVWS+GIVLWEIFTMGQTPYPTIQSDGMHQALRNG+RNEKP LASDEMYRLMLTIWNDDPL+R++F+E+++KL H+QL     + K++  +++++Q YSTT V
Sbjct:    1 LDLLPRKVNGSCYSSRLYLYNVEIKDQGFYSVEATLRMKNGSSHGLNFTYELKINIANILDPDKTNSILSTPQISFNLNSRVCINDRFDWICKVTPVVSYYVTIYKNNSNPNNITVLAESEVLQMNI------DGNSG------QGFYLKSSTVNYSVNSVQREHAGVYACRIINFKDYSSDHQNRHEPEVLMRLTVKDCVGNSYFTII-WYSISVGIIILVVISFLII--RLYNKYSNGYIVKTVIVQHPNKLYVPHDTCFPLLMPDITIKTIHKHINSSEDSLLQQKHFTNNSNIPFSQKISKYFRKSFIFSYRHVDVSSSNLDSPLGVISNTETNKLTSNSLTVETQRPQLILQNDANTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFSENSASVEVAIKTLHTSFGDQDVINLIQELEMMKIIGRHRHIISLYGACIDNGHPYMVIELAKHGNLRDFLRAQRSQSKVGEIQNSGGLVTRLTVTDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQYVEMKIADFGLTRIVENYYRKTTDGRLPIKWMAPECLLDRVYTVKSDVWSYGIVLWEIFTMGQTPYPTIQSDGMHQALRNGIRNEKPALASDEMYRLMLTIWNDDPLERHTFSEIIDKLTHIQLSNGGSSPKRDYLEISSNQCYSTTIV 666          
BLAST of Fibroblast growth factor receptor 2 vs. TrEMBL
Match: T1G069 (Protein kinase domain-containing protein OS=Helobdella robusta OX=6412 GN=20214467 PE=3 SV=1)

HSP 1 Score: 293.123 bits (749), Expect = 1.867e-87
Identity = 140/294 (47.62%), Postives = 203/294 (69.05%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENS--APIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVD--ITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAV--EHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            + Y +P +  W F R+ L + S +GEGAFG VY A       ++  A  +VA+K L  +  D+DV++L+QE+EMMKIIGRH++++SL G C  NG  ++++E A  GNLRDFLR +R +   +   +  +P+  +T  DL+ F+++IA+GME+L+S+M IHRDLAARNVLV +   +K++DFGLTR V    YY+K TDGRLP+KWMAPE L DR  T+KSDVWS+GI+LWE+F++G  PYP++  + + Q L+ G R E P  +S+E+Y LML+ W+  P  R SF ++V  L
Sbjct:    1 SDYEIPLDKAWEFPREKLQVSSILGEGAFGTVYMATAVGVDSSNPEASTKVAVKMLKENASDQDVVDLVQEMEMMKIIGRHKNVLSLLGCCTQNGPLFVILEYAANGNLRDFLRDKRPKNFRLQNCVVEVPLDYLTYKDLVTFALQIAKGMEFLASKMCIHRDLAARNVLVCEDYTLKVADFGLTRNVLKSDYYKKKTDGRLPVKWMAPEALFDRKCTVKSDVWSYGILLWELFSLGGNPYPSVPVEKIFQLLKAGYRMEAPVYSSNEIYSLMLSCWHQSPDHRPSFNKIVNSL 294          
BLAST of Fibroblast growth factor receptor 2 vs. TrEMBL
Match: V4ADF1 (Uncharacterized protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_91761 PE=3 SV=1)

HSP 1 Score: 300.442 bits (768), Expect = 1.988e-86
Identity = 143/302 (47.35%), Postives = 199/302 (65.89%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRR------------IQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y +P +  W F R+ L +G ++GEGAFG+V  A       N     VA+K L     D ++ +L+QE+E+MK++G H++II+L G C   G  ++++E A +GNLRDFL+ RR             +   +D  ++ V P+T  DL+ FS +IA GMEYL S+  IHRDLAARN+LV +   +KI+DFGLTR V+H  YY+KTTDGRLP+KWMAPE L D+ YT KSDVWS+G++LWE+FT+G  PYP+I  +G+   LR G R +KPP A  E+Y +ML  WND P  R SF++LV  L
Sbjct:  295 SEYEIPLDADWEFPRERLGLGERLGEGAFGLVMKAKAMGIANNPGQTTVAVKMLKDDSTDREMTDLMQEMEVMKVMGSHKNIINLLGCCTQRGPLFVIVEYAPHGNLRDFLKLRRPPNSTSCPSTPGYEKPVIDFNSVEVKPLTPKDLISFSYQIARGMEYLESKHCIHRDLAARNILVAEDYVLKIADFGLTRNVKHLDYYKKTTDGRLPVKWMAPEALFDKRYTSKSDVWSYGVLLWEVFTLGGNPYPSIPVEGLFDLLRKGHRMQKPPYAPSEIYSIMLQCWNDSPNVRPSFSQLVATL 596          
BLAST of Fibroblast growth factor receptor 2 vs. TrEMBL
Match: R7TUN2 (Protein kinase domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_220531 PE=3 SV=1)

HSP 1 Score: 293.893 bits (751), Expect = 3.469e-85
Identity = 146/303 (48.18%), Postives = 206/303 (67.99%), Query Frame = 1
Query: 1798 ILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFT-ENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVP-----ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAV--EHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++ + + ++Y +P +  W F RD L IG  +GEGAFG+V +A     T +    I VA+K L     D ++ +L+QE+EMMKIIGRHR+II+L G C  +G  ++++E A +GNLRDFL++RR+       T +   P     ++  DL+ F  ++A GMEYL+SRM IHRDLAARNVLV     +KI+DFGLTR +  + YYRKTTDGRLP+KWMAPE L DR YT+KSDVWS+G++LWEIF++G  PYP++  + +   LR+G R E+P  +S E+Y LML  W+++P  R SFT+L + L
Sbjct:  143 VMSDISLSEYEIPLDEEWEFPRDKLKIGEPLGEGAFGVVIAAEATGITGDKQRTITVAVKKLKCDATDRELADLVQEMEMMKIIGRHRNIINLLGCCTQSGPLFVIVEFAPHGNLRDFLKSRRLDLPPGCNTGLVRRPNHNKSLSFRDLVSFGYQVARGMEYLASRMCIHRDLAARNVLVGDEYIVKIADFGLTRNIPSQDYYRKTTDGRLPVKWMAPEALFDRKYTVKSDVWSYGVLLWEIFSLGGNPYPSVPVEMLFDLLRDGHRMERPLHSSLEIYNLMLECWHENPGQRPSFTDLKDDL 445          
BLAST of Fibroblast growth factor receptor 2 vs. TrEMBL
Match: R7TKL8 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_90852 PE=3 SV=1)

HSP 1 Score: 297.745 bits (761), Expect = 4.338e-85
Identity = 156/349 (44.70%), Postives = 229/349 (65.62%), Query Frame = 1
Query: 1732 PNTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPV----VPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAV--EHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNSQFYS 2760
            PN+ ++ A    + +E  R ++  +  A ++Y++P +  W F RD L +G  +GEGAFG+V  A  +     S    VA+K L     D+++ +L+QELE+MKIIGRHR+II+L G C  +G  Y+++E A +GNLRDFLR RR  T +     +PV     PI+  DL+ +  ++A+GMEY +SRM IHRD+AARNVLV +   MKI+DFGLTR +    YYRKTTDGRLP+KWMAPE L DR YTIKSD+WS+G++LWEIF++G  PYP++  + + + LR G R E+P  ++ +MY +ML  W+ +P  R +F+ELV +L  +     ++T+ ++  DL+  Q  S
Sbjct:  275 PNSRSSLAPL--VKIEGGRNRLSSELTAMSEYVIPLDPQWEFPRDKLNLGKLLGEGAFGVVMQAEAQGGLGKSN--TVAVKMLKDGATDKELADLVQELEVMKIIGRHRNIINLLGCCTQDGPLYVIVEYAPHGNLRDFLRHRRPPTSSG--YEVPVDDFARPISFKDLVSYGYQVAKGMEYFTSRMCIHRDIAARNVLVGEDFVMKIADFGLTRNIPDNDYYRKTTDGRLPVKWMAPEALFDRRYTIKSDIWSYGVLLWEIFSLGGNPYPSVPVERLFELLREGHRMERPSCSTVDMYHIMLMCWHQNPDLRPTFSELVNELDRV----LALTVSEDYLDLDLCQLDS 613          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Cavefish
Match: fgfr1a (fibroblast growth factor receptor 1a [Source:NCBI gene;Acc:30705])

HSP 1 Score: 276.559 bits (706), Expect = 7.098e-80
Identity = 140/316 (44.30%), Postives = 204/316 (64.56%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAP--IEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNS 2748
            ++Y LP +  W   RD L++G  +GEG FG V    V    ++      +VA+K L +   ++D+ +LI E+EMMKIIG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR        +   +PV  +++ DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + H  YY+KTT+GRLP+KWMAPE L DRIYT +SDVWSFG++LWEIFT+G +PYP +  + + + L+ G R ++P   + E+Y +M   W+  P  R +F +LVE L        S+T  +E  DL+ S
Sbjct:  373 SEYELPQDPRWELPRDKLVLGKPLGEGCFGQVVMGEVLGMDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPTTCTHELYMMMRDCWHAIPSQRPTFKQLVEDLDRT----LSMTSNQEYLDLSVS 684          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Cavefish
Match: fgfr2 (fibroblast growth factor receptor 2 [Source:NCBI gene;Acc:352940])

HSP 1 Score: 273.092 bits (697), Expect = 3.289e-78
Identity = 135/293 (46.08%), Postives = 195/293 (66.55%), Query Frame = 1
Query: 1822 KYILPSNIGWIFSRDSLIIGSKIGEGAFG--IVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            +Y LP +  W FSRD L +G  +GEG FG  ++  AL     +    + VA+K L     ++D+ +L+ E+EMMK+IGRH++II+L GAC  +G  Y+++E A  GNLR++LR RR      + DI  +   P+T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWSFG+++WEIFT+G +PYP I  + + + L+ G R +KP   ++++Y +M   W+     R +F +LVE L
Sbjct:  429 EYDLPEDPRWEFSRDKLTLGKPLGEGCFGQVVMAEALGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDIARVSDEPLTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNDLYMMMKDCWHAISSQRPTFKQLVEDL 721          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Cavefish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 272.322 bits (695), Expect = 9.873e-78
Identity = 141/310 (45.48%), Postives = 203/310 (65.48%), Query Frame = 1
Query: 1831 LPSNIGWIFSRDSLIIGSKIGEGAFG--IVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN 2742
            LPS+  W F R  L +G  +GEG FG  ++  A+     + + P+ VA+K L     D+D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + D   IP   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWS+G++LWEIFT+G +PYP I  + + + L+ G R +KP   + E+Y +M   W+  P  R +F +LVE   H ++L  S+T   E  DL+
Sbjct:  462 LPSDPKWEFPRSKLTLGKALGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVED--HDRVL--SMTSTDEYLDLS 767          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Cavefish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 272.322 bits (695), Expect = 1.040e-77
Identity = 141/310 (45.48%), Postives = 203/310 (65.48%), Query Frame = 1
Query: 1831 LPSNIGWIFSRDSLIIGSKIGEGAFG--IVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN 2742
            LPS+  W F R  L +G  +GEG FG  ++  A+     + + P+ VA+K L     D+D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + D   IP   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWS+G++LWEIFT+G +PYP I  + + + L+ G R +KP   + E+Y +M   W+  P  R +F +LVE   H ++L  S+T   E  DL+
Sbjct:  461 LPSDPKWEFPRSKLTLGKALGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVED--HDRVL--SMTSTDEYLDLS 766          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Cavefish
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:58129])

HSP 1 Score: 261.922 bits (668), Expect = 2.393e-75
Identity = 139/310 (44.84%), Postives = 200/310 (64.52%), Query Frame = 1
Query: 1831 LPSNIGWIFSRDSLIIGSKIGEGAFG--IVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN 2742
            LPS+  W F R  L +G  +GEG FG  ++  A+     + + P+ VA+K L     D+D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + D   IP   +T  DL+  + ++A GME  +S   IHRDLAARNVLV +   MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWS+G++LWEIFT+G +PYP I  + + + L+ G R +KP   + E+Y +M   W+  P  R +F +LVE   H ++L  S+T   E  DL+
Sbjct:  295 LPSDPKWEFPRSKLTLGKALGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGME--ASWSCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVED--HDRVL--SMTSTDEYLDLS 598          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Sea Lamprey
Match: fgfr2 (fibroblast growth factor receptor 2 [Source:NCBI gene;Acc:352940])

HSP 1 Score: 266.159 bits (679), Expect = 6.102e-78
Identity = 137/315 (43.49%), Postives = 200/315 (63.49%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFG--IVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVP---ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLN 2742
            ++Y L  +  W FSR+ L +G  +GEG FG  ++  AL     + +  + VA+K L     D+D+ +L+ E+EMMK IG+H++II+L GAC   G  Y+++E A  GNLR+FLR RR                  +++ +L+ F+ ++A GMEYL+S+  IHRDLAARNVLV     MKI+DFGL R V +  YY+KT++GRLP+KWMAPE L DR+YT +SDVWSFG++LWEIFT+G +PYP I  + + + L+ G R ++P L S E+Y +M   W   P  R +F +LVE L  +     ++T ++E  DL+
Sbjct:  259 SEYELTEDPRWEFSREWLTLGKPLGEGCFGQVVMAEALGIDKEKPNRSLRVAVKMLKEDATDKDLYDLVSEMEMMKNIGKHKNIINLLGACTQGGPLYVIVEFAAKGNLREFLRARRPPGTEYTFEGAAAAQGEQLSIKELVSFTYQVARGMEYLASKKCIHRDLAARNVLVTDDNVMKIADFGLARDVNYIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDRPALCSTELYMMMKDCWAAVPSHRPTFKQLVEDLDRI----LTMTAQEEYLDLS 569          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Sea Lamprey
Match: fgfr2 (fibroblast growth factor receptor 2 [Source:NCBI gene;Acc:352940])

HSP 1 Score: 250.366 bits (638), Expect = 1.739e-72
Identity = 126/272 (46.32%), Postives = 178/272 (65.44%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSA--LVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNI----PVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMY 2610
            ++Y LP +  W F RD L +G  +GEG FG V  A  L     + + P  VA+K L     D+++ +L+ E+E+MK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR          I    P   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT + DVWSFG++LWEIFT+G +PYP I  + + + L+ G R +KP    +E+Y
Sbjct:  315 SEYELPEDPRWEFPRDRLTLGKPLGEGCFGQVVMADGLGVDKEKPNKPATVAVKMLKDDATDKELSDLVSEMEVMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGVGYSFDPIGYSDPSEQLTFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQCDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPSNCPNELY 586          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008763.1 (pep scaffold:Pmarinus_7.0:GL480478:1796:23946:1 gene:ENSPMAG00000007909.1 transcript:ENSPMAT00000008763.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 214.157 bits (544), Expect = 6.949e-61
Identity = 117/267 (43.82%), Postives = 160/267 (59.93%), Query Frame = 1
Query: 1849 WIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACV-DNGYPYMVIELAKYGNLRDFLRTRRIQTRAVD-----------ITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAV--EHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEM 2607
            W F R +L +G  +GEG FG V  A        +    VA+K L       ++ +L+ EL ++K +  H +II L+GAC  D G  Y+++E AKYG+LR FLR RR    AV            + N     +T+GDL+ F+ +I+ GM YL+   ++HRDLAARNVLV +  +MKISDFGL+R V     Y K T GR+P+KWMA E L + +YT +SDVWSFGI+LWEI T+G TPYP I  + +   L+ G R EKP   SD++
Sbjct:  201 WEFPRKNLALGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKECASHSELRDLLSELNLLKQV-NHPNIIRLHGACTQDEGPLYLIVEYAKYGSLRSFLRVRRKAEFAVPAGGASNRNSRLLDNPDERGLTLGDLVSFAWQISRGMTYLADMKLVHRDLAARNVLVAEGRKMKISDFGLSRDVYEGDSYVKRTKGRIPVKWMAIESLFEHMYTSQSDVWSFGILLWEIMTLGGTPYPGIPPERLFNLLKTGYRMEKPENCSDDL 466          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009485.1 (pep scaffold:Pmarinus_7.0:GL477866:1219:4704:1 gene:ENSPMAG00000008570.1 transcript:ENSPMAT00000009485.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 181.8 bits (460), Expect = 2.828e-51
Identity = 102/289 (35.29%), Postives = 162/289 (56.06%), Query Frame = 1
Query: 1849 WIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVI-ELAKYGNLRDFLRTRRIQTRAVDITNIPVV-------PITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAV--EHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLA 2685
            W   RD + +  ++G+G FG+VY  L +   +      VAIKT++ +    +    + E  +MK    H H++ L G  V    P +VI EL   G+L+ +LR+ R    A D T   V+       P ++ ++L+ + EIA+GM YL+++  +HRDLAARN +V +   +KI DFG+TR +    YYRK   G LP++WM+PE L D ++T  SDVWSFG+VLWEI T  + PY  + ++ + + + +G     PP   + +  L+   W  +P  R +F E+++ LA
Sbjct:    6 WEVERDKVKMMRELGQGTFGMVYEGLARGIVKGEDETRVAIKTVNETATMRERYEFLNEASVMKSFNCH-HVVRLLGV-VSQAQPILVIMELMTRGDLKSYLRSLR--PDAEDFTETIVLEKKPTRPPSSLPEMLQMAGEIADGMAYLNAKKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATQAEQPYQGLSNEQVLKFVMDGGLLVLPPACPERLQELIRKCWQYNPRMRPTFLEILDGLA 290          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009481.1 (pep scaffold:Pmarinus_7.0:GL477866:614:5163:1 gene:ENSPMAG00000008570.1 transcript:ENSPMAT00000009481.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 182.185 bits (461), Expect = 1.714e-49
Identity = 100/283 (35.34%), Postives = 159/283 (56.18%), Query Frame = 1
Query: 1849 WIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVI-ELAKYGNLRDFLRTRRIQTRAVDITNIPV-VPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAV--EHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLA 2685
            W   RD + +  ++G+G FG+VY  L +   +      VAIKT++ +    +    + E  +MK    H H++ L G  V    P +VI EL   G+L+ +LR+ R      D    P   P ++ ++L+ + EIA+GM YL+++  +HRDLAARN +V +   +KI DFG+TR +    YYRK   G LP++WM+PE L D ++T  SDVWSFG+VLWEI T  + PY  + ++ + + + +G     PP   + +  L+   W  +P  R +F E+++ LA
Sbjct:   54 WEVERDKVKMMRELGQGTFGMVYEGLARGIVKGEDETRVAIKTVNETATMRERYEFLNEASVMKSFNCH-HVVRLLGV-VSQAQPILVIMELMTRGDLKSYLRSLR-----PDAEKKPTRPPSSLPEMLQMAGEIADGMAYLNAKKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATQAEQPYQGLSNEQVLKFVMDGGLLVLPPACPERLQELIRKCWQYNPRMRPTFLEILDGLA 329          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144])

HSP 1 Score: 93.9745 bits (232), Expect = 5.903e-20
Identity = 73/270 (27.04%), Postives = 130/270 (48.15%), Query Frame = 1
Query: 1888 IGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH-YYRKTTDGRLPIKWMAPECLLDRI-YTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIW-----NDDPLDRYSFTELVE 2676
            IG G FG+VY    K +   +  +  AIK L+     ++V ++ +E++ +  + +  +I   YG+ + +   ++++E    G+LR  LR  +I  + +            G ++R   E+   ++ +    +IHRD+ A NVL+     +K+ DFG+   V     R+ T    P  WMAPE +++ + Y  K D+WS GI  +EI T G  PY  +++    Q     +   KPP   D  Y   L  +     ++DP +R S  +L++
Sbjct:   29 IGRGKFGVVY----KGYNVKTGRV-YAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYI------------GVIMR---ELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPY-WMAPEVIMEGVYYDTKVDIWSLGITTYEIAT-GNPPYCDVEALRAMQL----IIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLK 272          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Yeast
Match: STE7 (Signal transducing MAP kinase kinase; involved in pheromone response where it phosphorylates Fus3p; involved in the pseudohyphal/invasive growth pathway where it phosphorylates of Kss1p; phosphorylated by Ste11p; degraded by ubiquitin pathway [Source:SGD;Acc:S000002318])

HSP 1 Score: 89.3521 bits (220), Expect = 6.459e-19
Identity = 91/339 (26.84%), Postives = 158/339 (46.61%), Query Frame = 1
Query: 1726 GLPNTATNQATSNSLTVEPRRPQII-LQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVIN-LIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVPITVGDLL--RFSIEIAEGMEYLSSR-MIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQS--DGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMK 2721
            GL N AT     +S+++ P    +     D        SN  +I  +D + +G KIG G  G V    VK+     + I VA KT+     +  +IN L++EL ++K +  H +II+ YGA  +      +I L +Y +     +   +  R V    +        +L   + +  +  G+++L  +  IIHRD+   NVL++   ++K+ DFG+++ + +    T  G     +M+PE +   +Y+IK DVWS G+++ E+ T G+ P        DG+   L+  V    P L  D +Y   +T    D ++R       E+ +  +LL   + MK
Sbjct:  143 GLSNIATPVENEHSISLPPLEESLSPAAADLKDTLSGTSNGNYIQLQDLVQLG-KIGAGNSGTV----VKALHVPDSKI-VAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVG--TSTYMSPERIQGNVYSIKGDVWSLGLMIIELVT-GEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMT----DFVNRCCIKNERERSSIHELLHHDLIMK 468          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999])

HSP 1 Score: 87.8113 bits (216), Expect = 4.094e-18
Identity = 78/269 (29.00%), Postives = 132/269 (49.07%), Query Frame = 1
Query: 1885 KIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAV-EHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWND-----DPLDRYSFTELV 2673
            KIG+GA G VY+A      E    + VAIK ++     +  + +I E+ +MK   +H +I++   + V  G  ++++E  + G+L D +      T  +         +T G +     E   G+E+L S+ ++HRD+ + N+L+    ++K++DFG    + E   ++TT    P  WMAPE +  + Y  K D+WS GI++ E+   G+ PY    ++   +AL     N  P L   E     L  + D     +P DR S TEL+
Sbjct:  625 KIGQGASGGVYTAY-----EIGTNVSVAIKQMNLEKQPKKEL-IINEILVMKG-SKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVV------THCI---------LTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPY-WMAPEVVSRKEYGPKVDIWSLGIMIIEMIE-GEPPY---LNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELL 866          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603])

HSP 1 Score: 87.0409 bits (214), Expect = 6.960e-18
Identity = 69/273 (25.27%), Postives = 132/273 (48.35%), Query Frame = 1
Query: 1879 GSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDV-INLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH-YYRKTTDGRLPIKWMAPECLLDR--IYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRN---GVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVE 2676
            G  +GEG F   +        ++S  I  A      S   E     L+ E+++ K +  H +I+       D+   Y+++E+   G+L + L+ R++              +T  ++  F+ +I   ++Y+ SR +IHRDL   N+  D    +KI DFGL   + +   RK T    P  ++APE L+ +   ++ + D+WS G++L+ +  +G+ P+     + +++ ++        +KP   SDE   L+  I + DP++R S TE+++
Sbjct:   85 GHFLGEGGFARCFQ-----IKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMS-HPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKV--------------LTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTP-NYIAPEVLMGKHSGHSFEVDIWSLGVMLYALL-IGKPPFQARDVNTIYERIKCRDFSFPRDKP--ISDEGKILIRDILSLDPIERPSLTEIMD 333          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Yeast
Match: KIN2 (Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; KIN2 has a paralog, KIN1, that arose from the whole genome duplication [Source:SGD;Acc:S000004086])

HSP 1 Score: 86.2705 bits (212), Expect = 1.361e-17
Identity = 68/224 (30.36%), Postives = 112/224 (50.00%), Query Frame = 1
Query: 2017 IQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRK---TTDGRLPIKWMAPECLLDRIYT-IKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVE 2676
            ++E  + +I+  H HI  L+  C  + + YM+ E    G L D++    IQ  +          +      +F+  IA  ++YL +  I+HRDL   N+++    E+KI DFGL+   +  YRK   T  G L   + APE L  + YT  + D+WSFGIVL+ +   G+ P+    S  +H+ ++ G + + P   S E+  L+  +   DPL R +   +VE
Sbjct:  171 VREASLGQIL-YHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYI----IQHGS----------LKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFD--YRKQLHTFCGSL--YFAAPELLKAQPYTGPEVDIWSFGIVLY-VLVCGKVPFDDENSSILHEKIKKG-KVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVE 373          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Nematostella
Match: EDO49315 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHA0])

HSP 1 Score: 264.233 bits (674), Expect = 3.914e-80
Identity = 134/278 (48.20%), Postives = 181/278 (65.11%), Query Frame = 1
Query: 1849 WIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVE 2676
            W F R  L+I   +GEGAFG V  A       NSA   VA+K L     ++++ +L+ E+E+MK IG+H +II+L G C  +G  ++++E A++GNLR FLR RR      D+   P   +T+ +L+ F  +IA+GMEYL+SR  IHRDLAARN+LV     +KI+DFGL R V +  YYRKTTDGRLP+KWMA E L DR+YT +SDVWSFGIV+WEI T G TPYP +  + +   L  G R E+P   S E+Y +M   WN++P  R +FT LV+
Sbjct:   52 WEFDRTYLVIREVLGEGAFGKVMRAEAFGLHGNSACTTVAVKMLKEDATEQELFDLVSEMEVMKSIGKHINIINLLGTCTQHGPLFVLVEYARWGNLRQFLRDRRPVKDYDDVME-PAETLTLLNLMTFCYQIAKGMEYLASRKCIHRDLAARNILVADDNILKIADFGLARDVHNVDYYRKTTDGRLPVKWMAFEALFDRVYTTQSDVWSFGIVVWEIITFGGTPYPGVPIEKLCMLLNTGYRMERPVNCSKELYEIMRNCWNENPEARPTFTSLVQ 328          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Nematostella
Match: EDO43236 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ71])

HSP 1 Score: 265.388 bits (677), Expect = 2.499e-77
Identity = 137/295 (46.44%), Postives = 188/295 (63.73%), Query Frame = 1
Query: 1825 YILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRI----QTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHM 2691
            Y LP +  W   R  + I  ++GEGAFG+V  A     T+      VA+K L     + ++ +L+ E++ MK IG H++II+L GAC  NG  Y+V+E A +GNLR FLR RR     ++R+ D +      + V D + F+ +IA GMEYLS +  IHRDLAARN+LV +   MKI+DFGL R V    YYRK TDGRLPIKW+A E L DR+YT +SDVW+FGI+LWEIFT+G +PYP I  + + + L++G R + P    D+MY +ML+ WN++P  R SFTEL  +   M
Sbjct:  319 YELPIDEDWEIDRSQITIKEQLGEGAFGLVMKAEALGLTDMPYRHTVAVKMLKADATENELADLLSEMDTMKNIGSHKNIINLIGACTQNGPLYVVVEFAPHGNLRQFLRERRPSDYHRSRS-DSSTHSQPSLIVRDFISFAFQIARGMEYLSFKKCIHRDLAARNILVGEDYVMKIADFGLARNVRDMDYYRKATDGRLPIKWLAIEALFDRVYTTQSDVWTFGILLWEIFTLGGSPYPGIPVEKLFELLKSGYRMQMPQKCPDKMYDIMLSCWNENPNARPSFTELRAEFDKM 612          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Nematostella
Match: EDO49191 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHA4])

HSP 1 Score: 251.136 bits (640), Expect = 2.801e-72
Identity = 129/287 (44.95%), Postives = 179/287 (62.37%), Query Frame = 1
Query: 1831 LPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRR-IQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            LP +  W   R  + +   +GEGAFG V  A             VA+K L     + ++ +L+ E+E+MK IG+H +II+L GAC   G  ++V+E A  GNLR FLR RR I   A  +T  P   + + DL+ FS ++A GMEYL S+  IHRDLAARNVLV     +KI+DFGL R +    YYRKTTDGRLP+KWMA E L DR+YT +SDVW++GI++WEI T G +PYP I    + + L+ G R E+P    D++Y LML  W+++P  R +F E+V+++
Sbjct:  310 LPLDEEWELDRSQISLLGILGEGAFGRVVKADAIGLPNMPYRCNVAVKMLKEDATEHELADLVSEMEVMKTIGQHVNIINLIGACTQKGPLFVVVEYASQGNLRQFLRARRPIPEYANPLTEPPREKLKLVDLVSFSYQVARGMEYLESKKCIHRDLAARNVLVSDNHVIKIADFGLARDIHDIDYYRKTTDGRLPVKWMALEALFDRVYTAQSDVWAYGILMWEIVTFGGSPYPGIPLWKLFELLKEGYRMEQPVNCQDDVYALMLRCWHENPNQRPTFAEIVKEM 596          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Nematostella
Match: EDO43234 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ69])

HSP 1 Score: 233.032 bits (593), Expect = 2.269e-69
Identity = 118/292 (40.41%), Postives = 180/292 (61.64%), Query Frame = 1
Query: 1834 PSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRR-IQTRAVDITNIPVVP---ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHM 2691
            P +  W  +R+++++  KIGEGAFG+V   +V    +  +   VA+KT+      E+  + + E+E MK IG H +II++ G C  +G   +++E A +GNLRDFLR  R     A    N+ + P   + + +LL  + + A+GM+YL+S+  IHRDLAARNVL+     +KI+DFGL+R +    YYRKTT GRLP+ W++ E L D+ YT+ SDVWSFG++LWEI+T+G  PYP I  + + + L+ G R   P     E+Y LML  W+++P DR +   + ++L  M
Sbjct:    4 PFDEEWEIARENIVLREKIGEGAFGLVVKGIVYGLPDKPSSCTVAVKTIKEDASIEEFNDFVSEIETMKSIGNHTNIINMVGVCSVDGPLLLIVEHAMHGNLRDFLRKHRGTHKDASQNNNLYMTPGNSLIIKNLLPMAYQAAKGMQYLASKKCIHRDLAARNVLLADDYVLKIADFGLSRNLRETDYYRKTTHGRLPVMWLSIEALFDQKYTLMSDVWSFGVLLWEIYTLGCMPYPGIPVERLFELLKTGYRMSAPTECPPEIYTLMLQCWSENPADRPTMELVAKELDRM 295          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Nematostella
Match: EDO49126 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGW8])

HSP 1 Score: 232.646 bits (592), Expect = 1.016e-68
Identity = 122/295 (41.36%), Postives = 173/295 (58.64%), Query Frame = 1
Query: 1831 LPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFT---ENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRR--IQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAV---EHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHM 2691
            +P    W     S+  G  +G GAFG V  A +       EN   + VA+K L+     ED  N + E+EMMK +G+H +I+S+ G     G   ++ E   YG+LR++LR  R  + TR       P   +T  DLL F+ +IA GMEYLS +M +HRDLAARN+L+ +   +KISDFGLTR V     Y++    G+LP+KWMAPE +   ++T KSDVW+FG+VLWEI T+G +PYP       ++ L+NG R EKP + S E+Y +M + W   P DR +FT+L  +L  +
Sbjct:    5 IPEPDEWEVDYSSIAFGEVVGSGAFGKVTKATIVGLPGGPENKETV-VAVKKLNAMATMEDRRNFLSEIEMMKQLGKHLNIVSILGCVTHAGQLCLITEYCPYGDLRNYLRAIRDKVSTRDSLAGRAPGRELTQNDLLSFARQIAVGMEYLSQKMFVHRDLAARNILICEDNLVKISDFGLTRDVYESSEYHKMHNTGKLPLKWMAPEAIFQNVHTTKSDVWAFGVVLWEIVTLGGSPYPGQSGKEFYKKLKNGYRMEKPDMCSPELYAMMRSCWASSPEDRPTFTKLRNQLEQL 298          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Medaka
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:100049424])

HSP 1 Score: 270.781 bits (691), Expect = 3.569e-78
Identity = 135/290 (46.55%), Postives = 191/290 (65.86%), Query Frame = 1
Query: 1831 LPSNIGWIFSRDSLIIGSKIGEGAFG--IVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            LPS+  W F R  L +G  +GEG FG  ++  A+     + + P+ VA K L     D+D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + D   IP   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV     MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWS+G++LWEIFT+G +PYP I  + + + L+ G R +KP   + E+Y +M   W+  P  R +F +LVE L
Sbjct:  336 LPSDPKWEFPRTRLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAAKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEFASKGNLREYLRARRPPGMDYSFDTCKIPDEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDL 625          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Medaka
Match: fgfr1 (fibroblast growth factor receptor 1 [Source:NCBI gene;Acc:100125448])

HSP 1 Score: 273.092 bits (697), Expect = 7.464e-78
Identity = 138/315 (43.81%), Postives = 201/315 (63.81%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAP--IEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL-------AHMQLLECSVTMKK 2724
            ++Y LP +  W   RD L++G  +GEG FG V    V    +        VA+K L +   ++D+ +LI E+EMMKIIG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR        +   + V  +++ DL+  + ++A GMEYL+S+  IHRDLAARNVLV +   MKI+DFGL R + H  YY+KTT+GRLP+KWMAPE L DRIYT +SDVWSFG++LWEIFT+G +PYP +  + + + L+ G R +KP   + E+Y +M   W+  P  R +F +LVE L       ++ + LE SV + +
Sbjct:  472 SEYELPQDPRWEVPRDKLVLGKPLGEGCFGQVMMGEVLGLDKEKPNRVTNVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPDQVSVETMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDLDRCLAMTSNQEYLELSVPLDQ 786          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Medaka
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:100049424])

HSP 1 Score: 271.166 bits (692), Expect = 2.953e-77
Identity = 135/290 (46.55%), Postives = 191/290 (65.86%), Query Frame = 1
Query: 1831 LPSNIGWIFSRDSLIIGSKIGEGAFG--IVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            LPS+  W F R  L +G  +GEG FG  ++  A+     + + P+ VA K L     D+D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + D   IP   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV     MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWS+G++LWEIFT+G +PYP I  + + + L+ G R +KP   + E+Y +M   W+  P  R +F +LVE L
Sbjct:  467 LPSDPKWEFPRTRLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAAKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEFASKGNLREYLRARRPPGMDYSFDTCKIPDEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDL 756          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Medaka
Match: fgfr3 (fibroblast growth factor receptor 3 [Source:NCBI gene;Acc:100049424])

HSP 1 Score: 270.781 bits (691), Expect = 4.048e-77
Identity = 135/290 (46.55%), Postives = 191/290 (65.86%), Query Frame = 1
Query: 1831 LPSNIGWIFSRDSLIIGSKIGEGAFG--IVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTR--AVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            LPS+  W F R  L +G  +GEG FG  ++  A+     + + P+ VA K L     D+D+ +L+ E+EMMK+IG+H++II+L GAC  +G  Y+++E A  GNLR++LR RR      + D   IP   +T  DL+  + ++A GMEYL+S+  IHRDLAARNVLV     MKI+DFGL R V +  YY+KTT+GRLP+KWMAPE L DR+YT +SDVWS+G++LWEIFT+G +PYP I  + + + L+ G R +KP   + E+Y +M   W+  P  R +F +LVE L
Sbjct:  467 LPSDPKWEFPRTRLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAAKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEFASKGNLREYLRARRPPGMDYSFDTCKIPDEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDL 756          
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Medaka
Match: ENSORLT00000000391.2 (fibroblast growth factor receptor 1-A [Source:NCBI gene;Acc:101155126])

HSP 1 Score: 265.388 bits (677), Expect = 4.345e-76
Identity = 135/295 (45.76%), Postives = 191/295 (64.75%), Query Frame = 1
Query: 1819 TKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAP---IEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRR-IQTRAVDITNIPVVP-ITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEH--YYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            ++Y LP +  W   RD L +G  +GEG FG V  A      + S P    +VA+K L     ++D+ +LI E+EMMK+IG+H++II+L GAC   G  Y+V+E A  GNLR++LR RR +          P++  + + +L+  + ++A GM YL+S+  IHRDLAARNVLV +   MKI+DFGL R + H  YY+KTT+GRLP+KWMAPE L DRIYT +SDVWSFG++LWEIFT+G +PYP +  + + + L+ G R EKP   + E+Y +M   W+  P  R +F +LVE L
Sbjct:  373 SEYELPYDPAWELPRDRLTLGKPLGEGCFGQVVLAEAVGL-DRSKPARLTKVAVKMLKADASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQEGPLYVVVEYASKGNLREYLRARRPVGGEYWSGARQPLLGGVEIRELVSAAYQVARGMSYLASKKCIHRDLAARNVLVTEDDVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMEKPSACTQELYLMMRDCWHAVPSRRPTFQQLVEDL 666          
BLAST of Fibroblast growth factor receptor 2 vs. Planmine SMEST
Match: SMESG000010479.1 (SMESG000010479.1)

HSP 1 Score: 1808.88 bits (4684), Expect = 0.000e+0
Identity = 883/890 (99.21%), Postives = 886/890 (99.55%), Query Frame = 1
Query:  103 MLTDPVLVTIAITVAMTIFTFSYANHCQFKLTADETIYFAPLTPFSLNCRPQFDTDPDLCAHIQPPYRWTRDNRTVTPKEGRIKFVESSQTMIVFNGSETDQGQYECSTIDNNHKQFFVHLTSPSLMQKNLLPNAFPNDPKEEVKGRIYWLPEMLLRQNRQLVIANEGERVELHGAHYVSSEEAAISVFDVHWYYQRNATKDIFKGMKTNFNSSCKHLDFLPRNVSGFCHNSQITFEDLTTLNQGFYICAANMILKNGQQDSLNFTYELRINFAQIFDKNTQPEVYPQITFNQDARACTKDKYEWSCNVTPKKTYVTSIYRIDSHPETLLAKSKLKTINITDYKKENGETAAVEDFRETFVVEDFQSCFVQKSLKVKDAGVYECRVFKVDDLFKASTYEFKKVMHLTVQDCFEKQDFSVTSWXXXXXXXXXXXXXXXXXXXYRIYKKYSNNYLVKTVIVQLPNKLYVPHDKCFPLIMPEVSIKTTRRHRNSYEESLLQQKHSDSSSNIPFSNKLSKYFKKPFVISYRHVDLSGSKSDSPTDGLPNTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNSQFYSTTNV 2772
            MLTDPVLVTIAITVAMTIFTFSYANHCQFKLTADETIYFAPLTPFSLNCRPQFDTDPDLCAHIQPPYRWTRDNRTVTPKEGRIKFVESSQTMIVFNGSETDQGQYECSTIDNNHKQFFVHLTSPSLMQKNLLPNAFPNDPKEEVKGRIYW PEMLLRQNRQLVIANEGERVELHGAHYVSSEEAAISVFDVHWYYQRNATK IFKGMKTNFNSSCKHLDFLPRNVSGFCHNSQITFEDL+TLNQGFYICAANMILKNGQQDSLNFTYELRINFAQIFDKNTQPEVYPQITFNQDARACTKDKYEWSCNVTPKKTYVTSIYRIDSHPETLLAKSKLKTINITDYKKENGETAAVEDFRETFVVEDFQSCFVQKSLKVKDAGVYECRVFKVDDLFKASTYEFKKVMHLTVQDCFEKQ+FSVTSWIAAAAIICSAFIAIFAIFSYRIYKKYSNNYLVKTVIVQLPNKLYVPHDKCFPLIMPEVSIKTTRRHRNSYE+SLLQQKHSDSSSNIPFS KLSKYFKKPFVISYRHVDLSGSKSDSPTDGL NTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNSQFYSTTNV
Sbjct:    1 MLTDPVLVTIAITVAMTIFTFSYANHCQFKLTADETIYFAPLTPFSLNCRPQFDTDPDLCAHIQPPYRWTRDNRTVTPKEGRIKFVESSQTMIVFNGSETDQGQYECSTIDNNHKQFFVHLTSPSLMQKNLLPNAFPNDPKEEVKGRIYWQPEMLLRQNRQLVIANEGERVELHGAHYVSSEEAAISVFDVHWYYQRNATKYIFKGMKTNFNSSCKHLDFLPRNVSGFCHNSQITFEDLSTLNQGFYICAANMILKNGQQDSLNFTYELRINFAQIFDKNTQPEVYPQITFNQDARACTKDKYEWSCNVTPKKTYVTSIYRIDSHPETLLAKSKLKTINITDYKKENGETAAVEDFRETFVVEDFQSCFVQKSLKVKDAGVYECRVFKVDDLFKASTYEFKKVMHLTVQDCFEKQEFSVTSWIAAAAIICSAFIAIFAIFSYRIYKKYSNNYLVKTVIVQLPNKLYVPHDKCFPLIMPEVSIKTTRRHRNSYEDSLLQQKHSDSSSNIPFSQKLSKYFKKPFVISYRHVDLSGSKSDSPTDGLSNTATNQATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKLAHMQLLECSVTMKKEARDLNNSQFYSTTNV 890          
BLAST of Fibroblast growth factor receptor 2 vs. Planmine SMEST
Match: SMESG000054557.1 (SMESG000054557.1)

HSP 1 Score: 278.485 bits (711), Expect = 4.262e-80
Identity = 136/289 (47.06%), Postives = 190/289 (65.74%), Query Frame = 1
Query: 1825 YILPSNIGWIFSRDSL-IIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTR--RIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            Y  P +  W F RD L I   K+GEGAFG+VY  L     +     +VA+K +   F D +V + ++E+E+MK IGRH ++I L G C  NG   +++ELA YGNLRDF+R++  +   +  +I N+     T   L  +S +IA GM YL+SR ++HRDL+ARN+LV ++ EMKI+DFGLTR V++YYRK TDG LP+KWMAPE LL++ YT KSDVWS+GI+LWEIFT+G  PY +I  + +   ++ G +N +P LA+ E+Y LM   WN    +R  F E+VE L
Sbjct:  506 YEFPCDPEWEFPRDKLKITNKKLGEGAFGMVYEGLTNDIAKKPTFTKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQNGPLRVIVELAPYGNLRDFVRSKNNKYSKQKKNIENL-----TASILSTYSFQIANGMTYLASRSVVHRDLSARNILVGEHYEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDAPYSSILPEKVVDVIKKGFQNPQPELANFEIYSLMQHCWNISTENRPHFFEIVETL 789          
BLAST of Fibroblast growth factor receptor 2 vs. Planmine SMEST
Match: SMESG000054557.1 (SMESG000054557.1)

HSP 1 Score: 278.485 bits (711), Expect = 6.895e-80
Identity = 136/289 (47.06%), Postives = 190/289 (65.74%), Query Frame = 1
Query: 1825 YILPSNIGWIFSRDSL-IIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTR--RIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            Y  P +  W F RD L I   K+GEGAFG+VY  L     +     +VA+K +   F D +V + ++E+E+MK IGRH ++I L G C  NG   +++ELA YGNLRDF+R++  +   +  +I N+     T   L  +S +IA GM YL+SR ++HRDL+ARN+LV ++ EMKI+DFGLTR V++YYRK TDG LP+KWMAPE LL++ YT KSDVWS+GI+LWEIFT+G  PY +I  + +   ++ G +N +P LA+ E+Y LM   WN    +R  F E+VE L
Sbjct:  527 YEFPCDPEWEFPRDKLKITNKKLGEGAFGMVYEGLTNDIAKKPTFTKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQNGPLRVIVELAPYGNLRDFVRSKNNKYSKQKKNIENL-----TASILSTYSFQIANGMTYLASRSVVHRDLSARNILVGEHYEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDAPYSSILPEKVVDVIKKGFQNPQPELANFEIYSLMQHCWNISTENRPHFFEIVETL 810          
BLAST of Fibroblast growth factor receptor 2 vs. Planmine SMEST
Match: SMESG000054557.1 (SMESG000054557.1)

HSP 1 Score: 278.1 bits (710), Expect = 7.683e-80
Identity = 136/289 (47.06%), Postives = 190/289 (65.74%), Query Frame = 1
Query: 1825 YILPSNIGWIFSRDSL-IIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTR--RIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            Y  P +  W F RD L I   K+GEGAFG+VY  L     +     +VA+K +   F D +V + ++E+E+MK IGRH ++I L G C  NG   +++ELA YGNLRDF+R++  +   +  +I N+     T   L  +S +IA GM YL+SR ++HRDL+ARN+LV ++ EMKI+DFGLTR V++YYRK TDG LP+KWMAPE LL++ YT KSDVWS+GI+LWEIFT+G  PY +I  + +   ++ G +N +P LA+ E+Y LM   WN    +R  F E+VE L
Sbjct:  523 YEFPCDPEWEFPRDKLKITNKKLGEGAFGMVYEGLTNDIAKKPTFTKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQNGPLRVIVELAPYGNLRDFVRSKNNKYSKQKKNIENL-----TASILSTYSFQIANGMTYLASRSVVHRDLSARNILVGEHYEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDAPYSSILPEKVVDVIKKGFQNPQPELANFEIYSLMQHCWNISTENRPHFFEIVETL 806          
BLAST of Fibroblast growth factor receptor 2 vs. Planmine SMEST
Match: SMESG000054557.1 (SMESG000054557.1)

HSP 1 Score: 278.1 bits (710), Expect = 9.476e-80
Identity = 136/289 (47.06%), Postives = 190/289 (65.74%), Query Frame = 1
Query: 1825 YILPSNIGWIFSRDSL-IIGSKIGEGAFGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGRHRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTR--RIQTRAVDITNIPVVPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDFGLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIFTMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDRYSFTELVEKL 2682
            Y  P +  W F RD L I   K+GEGAFG+VY  L     +     +VA+K +   F D +V + ++E+E+MK IGRH ++I L G C  NG   +++ELA YGNLRDF+R++  +   +  +I N+     T   L  +S +IA GM YL+SR ++HRDL+ARN+LV ++ EMKI+DFGLTR V++YYRK TDG LP+KWMAPE LL++ YT KSDVWS+GI+LWEIFT+G  PY +I  + +   ++ G +N +P LA+ E+Y LM   WN    +R  F E+VE L
Sbjct:  523 YEFPCDPEWEFPRDKLKITNKKLGEGAFGMVYEGLTNDIAKKPTFTKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQNGPLRVIVELAPYGNLRDFVRSKNNKYSKQKKNIENL-----TASILSTYSFQIANGMTYLASRSVVHRDLSARNILVGEHYEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDAPYSSILPEKVVDVIKKGFQNPQPELANFEIYSLMQHCWNISTENRPHFFEIVETL 806          
The following BLAST results are available for this feature:
BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FGFR21.890e-8044.13fibroblast growth factor receptor 2 [Source:HGNC S... [more]
FGFR21.641e-7945.58fibroblast growth factor receptor 2 [Source:HGNC S... [more]
FGFR21.852e-7945.58fibroblast growth factor receptor 2 [Source:HGNC S... [more]
FGFR21.896e-7944.48fibroblast growth factor receptor 2 [Source:HGNC S... [more]
FGFR22.099e-7944.27fibroblast growth factor receptor 2 [Source:HGNC S... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
egl-151.560e-7038.62Myoblast growth factor receptor egl-15 [Source:Un... [more]
egl-151.560e-7038.62Myoblast growth factor receptor egl-15 [Source:Un... [more]
egl-151.560e-7038.62Myoblast growth factor receptor egl-15 [Source:Un... [more]
egl-151.560e-7038.62Myoblast growth factor receptor egl-15 [Source:Un... [more]
egl-151.600e-7038.62Myoblast growth factor receptor egl-15 [Source:Un... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
htl7.246e-7246.41gene:FBgn0010389 transcript:FBtr0083550[more]
htl7.246e-7246.41gene:FBgn0010389 transcript:FBtr0083549[more]
htl7.246e-7246.41gene:FBgn0010389 transcript:FBtr0083548[more]
btl4.834e-6342.72gene:FBgn0285896 transcript:FBtr0100676[more]
btl4.834e-6342.72gene:FBgn0285896 transcript:FBtr0075778[more]
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BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fgfr32.594e-8245.48fibroblast growth factor receptor 3 [Source:NCBI g... [more]
fgfr1a1.560e-8038.31fibroblast growth factor receptor 1a [Source:NCBI ... [more]
fgfr1a1.560e-8038.31fibroblast growth factor receptor 1a [Source:NCBI ... [more]
fgfr1b8.897e-8043.95fibroblast growth factor receptor 1b [Source:ZFIN;... [more]
fgfr1a1.763e-7944.30fibroblast growth factor receptor 1a [Source:NCBI ... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fgfr49.486e-8047.24fibroblast growth factor receptor 4 [Source:NCBI g... [more]
c1orf841.224e-7945.22chromosome 1 open reading frame 84 [Source:Xenbase... [more]
c1orf841.697e-7946.94chromosome 1 open reading frame 84 [Source:Xenbase... [more]
tirap2.639e-7945.92toll-interleukin 1 receptor (TIR) domain containin... [more]
c1orf844.101e-7946.94chromosome 1 open reading frame 84 [Source:Xenbase... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fgfr22.067e-8045.58fibroblast growth factor receptor 2 [Source:MGI Sy... [more]
Fgfr23.083e-8045.58fibroblast growth factor receptor 2 [Source:MGI Sy... [more]
Fgfr21.881e-7945.58fibroblast growth factor receptor 2 [Source:MGI Sy... [more]
Fgfr22.447e-7945.58fibroblast growth factor receptor 2 [Source:MGI Sy... [more]
Fgfr22.572e-7945.58fibroblast growth factor receptor 2 [Source:MGI Sy... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8MY85|FGFR2_DUGJA0.000e+056.97Fibroblast growth factor receptor 2 OS=Dugesia jap... [more]
sp|Q91147|FGFR2_NOTVI2.674e-7944.00Fibroblast growth factor receptor 2 OS=Notophthalm... [more]
sp|Q8MY86|FGFR1_DUGJA2.937e-7947.39Fibroblast growth factor receptor 1 OS=Dugesia jap... [more]
sp|Q91286|FGFR2_PLEWA1.370e-7841.21Fibroblast growth factor receptor 2 OS=Pleurodeles... [more]
sp|Q90Z00|FGR1A_DANRE2.096e-7844.30Fibroblast growth factor receptor 1-A OS=Danio rer... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
O761670.000e+061.82Receptor tyrosine kinase (Fragment) OS=Dugesia jap... [more]
T1G0691.867e-8747.62Protein kinase domain-containing protein OS=Helobd... [more]
V4ADF11.988e-8647.35Uncharacterized protein (Fragment) OS=Lottia gigan... [more]
R7TUN23.469e-8548.18Protein kinase domain-containing protein OS=Capite... [more]
R7TKL84.338e-8544.70Uncharacterized protein OS=Capitella teleta OX=283... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fgfr1a7.098e-8044.30fibroblast growth factor receptor 1a [Source:NCBI ... [more]
fgfr23.289e-7846.08fibroblast growth factor receptor 2 [Source:NCBI g... [more]
fgfr39.873e-7845.48fibroblast growth factor receptor 3 [Source:NCBI g... [more]
fgfr31.040e-7745.48fibroblast growth factor receptor 3 [Source:NCBI g... [more]
fgfr32.393e-7544.84fibroblast growth factor receptor 3 [Source:NCBI g... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fgfr26.102e-7843.49fibroblast growth factor receptor 2 [Source:NCBI g... [more]
fgfr21.739e-7246.32fibroblast growth factor receptor 2 [Source:NCBI g... [more]
ENSPMAT00000008763.16.949e-6143.82pep scaffold:Pmarinus_7.0:GL480478:1796:23946:1 ge... [more]
ENSPMAT00000009485.12.828e-5135.29pep scaffold:Pmarinus_7.0:GL477866:1219:4704:1 gen... [more]
ENSPMAT00000009481.11.714e-4935.34pep scaffold:Pmarinus_7.0:GL477866:614:5163:1 gene... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
KIC15.903e-2027.04Protein kinase of the PAK/Ste20 family, required f... [more]
STE76.459e-1926.84Signal transducing MAP kinase kinase; involved in ... [more]
STE204.094e-1829.00Cdc42p-activated signal transducing kinase; involv... [more]
CDC56.960e-1825.27Polo-like kinase; controls targeting and activatio... [more]
KIN21.361e-1730.36Serine/threonine protein kinase involved in regula... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO493153.914e-8048.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO432362.499e-7746.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO491912.801e-7244.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO432342.269e-6940.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO491261.016e-6841.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fgfr33.569e-7846.55fibroblast growth factor receptor 3 [Source:NCBI g... [more]
fgfr17.464e-7843.81fibroblast growth factor receptor 1 [Source:NCBI g... [more]
fgfr32.953e-7746.55fibroblast growth factor receptor 3 [Source:NCBI g... [more]
fgfr34.048e-7746.55fibroblast growth factor receptor 3 [Source:NCBI g... [more]
ENSORLT00000000391.24.345e-7645.76fibroblast growth factor receptor 1-A [Source:NCBI... [more]
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BLAST of Fibroblast growth factor receptor 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000010479.10.000e+099.21SMESG000010479.1[more]
SMESG000054557.14.262e-8047.06SMESG000054557.1[more]
SMESG000054557.16.895e-8047.06SMESG000054557.1[more]
SMESG000054557.17.683e-8047.06SMESG000054557.1[more]
SMESG000054557.19.476e-8047.06SMESG000054557.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024551 ID=SMED30024551|Name=Fibroblast growth factor receptor 2|organism=Schmidtea mediterranea sexual|type=transcript|length=3004bp
TCTCATGACGATATATAATGTAGCAGAAATTGAACAATCGATATTTGGAT
TTGATTTAAGTTTTCGCGATCTCAATGAAAAGTCGAGCAGTTGATCCTGA
TCATGTTAACTGATCCAGTTCTTGTTACCATTGCTATTACCGTGGCGATG
ACGATTTTCACATTCAGTTACGCCAATCATTGTCAGTTCAAATTGACAGC
GGATGAAACTATTTACTTTGCCCCTCTCACTCCGTTCAGCCTCAATTGCC
GCCCCCAATTCGACACCGATCCAGACCTTTGCGCACATATTCAACCCCCA
TACAGATGGACACGTGACAACCGCACCGTTACACCTAAAGAGGGGAGAAT
AAAGTTCGTGGAGTCCTCACAGACAATGATCGTATTCAACGGATCAGAGA
CCGACCAAGGCCAATACGAATGCAGCACAATCGATAATAATCATAAACAG
TTCTTTGTTCATTTGACGAGTCCTAGCCTGATGCAGAAAAACCTTTTACC
CAATGCATTCCCAAATGATCCTAAAGAAGAAGTCAAAGGTCGTATCTACT
GGCTACCGGAAATGTTACTGAGACAGAATAGGCAGCTAGTTATAGCAAAT
GAAGGAGAACGTGTCGAACTTCATGGGGCGCACTACGTGTCCTCTGAAGA
GGCAGCCATTTCAGTATTTGATGTCCATTGGTACTACCAGAGAAACGCTA
CCAAAGATATTTTTAAAGGCATGAAGACCAATTTCAATTCTTCTTGCAAA
CATTTGGATTTCCTTCCGCGCAACGTATCCGGATTTTGCCATAACAGTCA
AATAACCTTCGAAGACCTCACAACCTTGAATCAAGGGTTCTATATATGTG
CTGCAAATATGATATTGAAAAATGGACAGCAGGACAGTCTCAATTTTACA
TATGAACTTCGTATTAATTTTGCTCAAATTTTTGATAAAAACACGCAACC
GGAAGTATATCCTCAAATCACATTCAATCAGGATGCAAGAGCCTGTACAA
AGGACAAATACGAATGGAGTTGCAATGTCACCCCCAAGAAAACATATGTC
ACATCTATTTACAGAATAGATTCCCATCCTGAAACGCTTCTGGCAAAGTC
GAAACTCAAAACGATAAATATTACCGATTACAAGAAGGAAAACGGTGAAA
CTGCTGCTGTAGAGGATTTCAGAGAAACTTTTGTGGTGGAAGACTTTCAA
TCCTGCTTCGTCCAAAAATCACTGAAGGTGAAAGATGCTGGAGTTTATGA
ATGCCGCGTATTCAAGGTCGACGACCTCTTTAAGGCTTCGACTTACGAAT
TCAAAAAAGTCATGCATTTGACGGTTCAGGATTGTTTTGAAAAGCAAGAT
TTTTCTGTCACTTCCTGGATTGCAGCAGCAGCCATCATTTGCTCAGCTTT
TATTGCAATTTTTGCTATATTTTCCTACCGAATCTACAAGAAATATTCCA
ACAATTACCTCGTGAAAACTGTAATCGTTCAACTTCCAAACAAACTTTAC
GTTCCTCATGATAAATGCTTTCCTCTCATCATGCCAGAGGTGTCAATTAA
AACCACTCGGAGGCACAGAAACAGTTACGAGGAATCACTGTTGCAACAAA
AACATTCCGACAGCTCATCAAACATTCCATTTTCCAATAAATTATCCAAA
TATTTCAAGAAACCATTTGTTATCAGTTACCGGCATGTAGATCTTTCCGG
CTCGAAATCAGACTCCCCAACGGACGGCCTCCCCAACACAGCAACCAATC
AAGCGACATCGAATTCGTTGACTGTTGAGCCCCGAAGACCGCAAATCATT
CTACAGAACGATGCCCATACGAAATACATTTTGCCATCAAACATCGGCTG
GATATTCTCCAGGGACAGCTTGATAATAGGCTCCAAAATTGGTGAAGGCG
CCTTCGGAATTGTTTACTCAGCTTTGGTGAAATCCTTTACTGAAAATTCG
GCACCAATAGAAGTTGCAATAAAGACTTTACATACATCATTTGGAGACGA
GGATGTCATAAACTTGATTCAAGAGCTCGAAATGATGAAGATCATAGGGC
GGCACCGACATATTATCTCATTGTATGGAGCATGCGTTGATAATGGCTAT
CCTTACATGGTGATCGAATTGGCCAAGTACGGAAACCTACGGGATTTTCT
AAGGACAAGGCGCATTCAGACGAGAGCCGTGGATATAACCAACATTCCAG
TTGTCCCGATAACAGTTGGTGACCTTTTGAGATTCAGCATAGAAATTGCG
GAAGGAATGGAATACCTCTCCTCACGAATGATCATTCATCGAGACCTCGC
CGCTAGGAACGTGTTGGTGGACCAATATATGGAAATGAAAATTTCCGATT
TCGGACTGACGAGAGCGGTCGAGCATTATTATAGGAAAACCACTGACGGC
CGCCTGCCTATCAAATGGATGGCTCCCGAGTGCCTTCTGGACAGGATATA
TACTATCAAAAGCGATGTATGGTCCTTTGGCATAGTTCTCTGGGAGATAT
TCACTATGGGCCAGACCCCATATCCGACAATCCAGTCCGACGGAATGCAT
CAAGCGTTGAGAAATGGTGTTAGAAATGAAAAGCCACCTTTAGCATCAGA
TGAAATGTATCGGTTAATGCTCACTATATGGAACGATGATCCGCTGGACC
GCTACTCATTCACTGAATTGGTGGAGAAGCTCGCTCATATGCAACTTTTG
GAATGCAGTGTGACCATGAAAAAGGAAGCCAGAGATTTAAACAACAGTCA
GTTCTATTCCACAACAAATGTGTAAATAACAACATCTTTTAAACGTGCCA
ATTATTATGTACCTTCACTCAGTCCCATGATTGTCCACTTCCTGTTCCAG
ACTTTCCGATCTTTGCAAGCCTTGCCGTATATTTTTTGAGCCTTTTAATG
AACAGATTTTATTTTCATTTATTTGGTATGTGCTCATGCTTCATTTCATG
TGTAAATATTCTCATTTTTGATCTATGCAAATAAATAAGCTCCTGGAACC
CCGA
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protein sequence of SMED30024551-orf-1

>SMED30024551-orf-1 ID=SMED30024551-orf-1|Name=SMED30024551-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=891bp
MLTDPVLVTIAITVAMTIFTFSYANHCQFKLTADETIYFAPLTPFSLNCR
PQFDTDPDLCAHIQPPYRWTRDNRTVTPKEGRIKFVESSQTMIVFNGSET
DQGQYECSTIDNNHKQFFVHLTSPSLMQKNLLPNAFPNDPKEEVKGRIYW
LPEMLLRQNRQLVIANEGERVELHGAHYVSSEEAAISVFDVHWYYQRNAT
KDIFKGMKTNFNSSCKHLDFLPRNVSGFCHNSQITFEDLTTLNQGFYICA
ANMILKNGQQDSLNFTYELRINFAQIFDKNTQPEVYPQITFNQDARACTK
DKYEWSCNVTPKKTYVTSIYRIDSHPETLLAKSKLKTINITDYKKENGET
AAVEDFRETFVVEDFQSCFVQKSLKVKDAGVYECRVFKVDDLFKASTYEF
KKVMHLTVQDCFEKQDFSVTSWIAAAAIICSAFIAIFAIFSYRIYKKYSN
NYLVKTVIVQLPNKLYVPHDKCFPLIMPEVSIKTTRRHRNSYEESLLQQK
HSDSSSNIPFSNKLSKYFKKPFVISYRHVDLSGSKSDSPTDGLPNTATNQ
ATSNSLTVEPRRPQIILQNDAHTKYILPSNIGWIFSRDSLIIGSKIGEGA
FGIVYSALVKSFTENSAPIEVAIKTLHTSFGDEDVINLIQELEMMKIIGR
HRHIISLYGACVDNGYPYMVIELAKYGNLRDFLRTRRIQTRAVDITNIPV
VPITVGDLLRFSIEIAEGMEYLSSRMIIHRDLAARNVLVDQYMEMKISDF
GLTRAVEHYYRKTTDGRLPIKWMAPECLLDRIYTIKSDVWSFGIVLWEIF
TMGQTPYPTIQSDGMHQALRNGVRNEKPPLASDEMYRLMLTIWNDDPLDR
YSFTELVEKLAHMQLLECSVTMKKEARDLNNSQFYSTTNV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002075pigment cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR036179Ig-like_dom_sf
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR020635Tyr_kinase_cat_dom
IPR013783Ig-like_fold
IPR017441Protein_kinase_ATP_BS
IPR008266Tyr_kinase_AS
IPR007110Ig-like_dom
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
GO:0018108peptidyl-tyrosine phosphorylation
Vocabulary: molecular function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0005524ATP binding
GO:0005515protein binding
GO:0000166nucleotide binding
GO:0004714transmembrane receptor protein tyrosine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 831..853
score: 33.47
coord: 787..809
score: 63.54
coord: 768..778
score: 64.17
coord: 671..684
score: 47.47
coord: 721..739
score: 64.7
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 592..860
e-value: 3.1E-86
score: 288.9
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 590..860
e-value: 3.6E-118
score: 408.6
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 43..124
e-value: 2.3E-6
score: 29.4
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 677..886
e-value: 9.5E-54
score: 183.7
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 548..673
e-value: 1.7E-25
score: 91.4
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 253..417
e-value: 14.0
score: 1.2
coord: 61..284
e-value: 58.0
score: -0.8
coord: 688..889
e-value: 3.1E-61
score: 205.3
coord: 573..693
e-value: 2.3E-19
score: 66.7
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 536..559
NoneNo IPR availablePANTHERPTHR24416TYROSINE-PROTEIN KINASE RECEPTORcoord: 300..873
NoneNo IPR availablePANTHERPTHR24416:SF550FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1-RELATEDcoord: 300..873
NoneNo IPR availableCDDcd00192PTKccoord: 595..861
e-value: 1.59769E-125
score: 377.264
NoneNo IPR availableTMHMMTMhelixcoord: 417..439
NoneNo IPR availableTMHMMTMhelixcoord: 5..24
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 727..739
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 596..624
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 590..865
score: 41.771
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 5..107
score: 7.341
IPR036179Immunoglobulin-like domain superfamilySUPERFAMILYSSF48726Immunoglobulincoord: 61..110
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 561..859