Copine-3
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024549 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE9 (copine family member 9 [Source:HGNC Symbol;Acc:HGNC:24336]) HSP 1 Score: 359.377 bits (921), Expect = 2.850e-115 Identity = 203/491 (41.34%), Postives = 300/491 (61.10%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK----IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + + ISK +G A +G VI G V++ L+ G + E S+C++ +++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + + + +DWD D ++F IGEF+ +E Q +E++N RKK KKK Y NSG VT+ + V + +F+DY+ GGT LNF VAID T+SNG+ P+SLH++ + Y++A++AV EI+Q+YD+D+LFPA+GFGA++ P+ +I H++PL + +P C G+EGV+ +Y + L+ ++L GPTYFAPVI QV A + DGS Y+VLLI+TDG + D +TK+A++ AS LP+SII+VGVG F M+ LD D + A RD VQFVP R ++ D S N S LAK+VLAE+PEQLL YM +++
Sbjct: 64 NPDFVRKFVLDYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGS-----RVERTLT-GVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWD------RDGSHDF---IGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQ 535
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498]) HSP 1 Score: 350.903 bits (899), Expect = 8.065e-112 Identity = 203/491 (41.34%), Postives = 299/491 (60.90%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEE++ ++ +++ + +K +SK +G T+G ++ S G + V G I E + C++ + ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W++ +SV LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KKK Y+NSG VT+ + V + SF+DY+ GGT +NF VAID T+SNG+ P+SLH+++ N Y +A++AV EI+Q+YD+D++FPA GFGA++ PD +I HE+ L G+ NP+C G+EGV+ AY+ L++++L GPT FAPVI V A DGS YFVLLI+TDG + D +TK++++ AS LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D S N S LAK+VLAE+PEQ L YM +K
Sbjct: 74 NPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIV------GIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIK 545
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498]) HSP 1 Score: 349.362 bits (895), Expect = 1.937e-111 Identity = 203/491 (41.34%), Postives = 299/491 (60.90%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEE++ ++ +++ + +K +SK +G T+G ++ S G + V G I E + C++ + ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W++ +SV LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KKK Y+NSG VT+ + V + SF+DY+ GGT +NF VAID T+SNG+ P+SLH+++ N Y +A++AV EI+Q+YD+D++FPA GFGA++ PD +I HE+ L G+ NP+C G+EGV+ AY+ L++++L GPT FAPVI V A DGS YFVLLI+TDG + D +TK++++ AS LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D S N S LAK+VLAE+PEQ L YM +K
Sbjct: 62 NPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIV------GIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIK 533
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE5 (copine 5 [Source:HGNC Symbol;Acc:HGNC:2318]) HSP 1 Score: 341.658 bits (875), Expect = 6.577e-108 Identity = 199/509 (39.10%), Postives = 301/509 (59.14%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYG----NNESHSPI---------------CIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNL 1674
NP F + +DYFFEEKQ ++ +++ + +K +SK +G A T+G ++ S G ++K L+ G N+ + P+ I E S+C++ ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W++ + V LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KKK Y NSG VT+ + V + +F+DY+ GGT +NF VAID T+SNG+ +SLH++ N Y++A+ AV EI+Q YD+D++FPA GFGA++ PD ++ HE+PL G+ NP C G++G++ AYH L+ ++L GPT FAPV+ V A DGS Y VLLI+TDG + D +TK+A++ A+ LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LA++VLAE+P+QL+ YM +
Sbjct: 73 NPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGS-----RLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGI 563
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE2 (copine 2 [Source:HGNC Symbol;Acc:HGNC:2315]) HSP 1 Score: 325.094 bits (832), Expect = 4.321e-102 Identity = 200/498 (40.16%), Postives = 290/498 (58.23%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKIGCAEST-IGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEF-----SIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCD---GSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGN-EQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F + LDY FEE Q +K +F D S + E +G+ S G + + + L N++ I ++ I + + G LDKKDLFGKSDP++ YK + GK + +R+E+IK TL+P W+ V + LC+ +++ I V C+D+D G D EF + + S+P + FE IN +K++KKK Y NSGI+ +R+ ++++D SF+DY+ GG L F V ID T+SNG+ DPSSLH+I+ +NEY AI AV +I+Q+YD+D++FPA GFGA++ PD+K+ HE+ + + +NPFC GV+G+ AY L +I+ GPT F+P++ V A Q + YF+LLI+TDG + D ET+ AV++AS LP+SII+VGVG F M+ LD D +L+ E+A RD VQFVP R+F R AA K LAK VLAELP+Q++ Y NL P
Sbjct: 72 NPAFSKKFVLDYHFEEVQKLKFALF----DQDKSSMRLDEHDFLGQFSCSLGTIVSSKKITRPLLLLNDKPAGKGLITIAAQELSDNRVITLSLAGRRLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGG--HDFIGEFQTSVSQMCEARDSVPLE-----------FECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREF-RNAA---------KETLAKAVLAELPQQVVQYFKHKNLPP 542
BLAST of Copine-3 vs. Ensembl Celegans
Match: gem-4 (Gon-2 Extragenic Modifier [Source:UniProtKB/TrEMBL;Acc:Q22422]) HSP 1 Score: 263.462 bits (672), Expect = 2.444e-78 Identity = 178/512 (34.77%), Postives = 273/512 (53.32%), Query Frame = 1
Query: 211 DQNPIFKCQLNLDYFFEEKQCIKVEIFGL------AKDSKISKIGCAESTIGRVI-------HSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCK-ENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQE------RKFELIN-SRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGS-HYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
D NP FK + YFFEE Q + E++ + A S +G E + +++ H GG+ + + N + S +R + D K E I+ + G LD+KD FGKSDPY+ ++ + G +++E+ TLNP W ++++S + LC KN+ I ++C+D + K D+IIG A+ L I++ + LIN +K KK Y NSG++ + ++ + +F+D++ GGT L+F VA+D T+SNG+ P SLH++ N+Y IA+++VL I Q Y++ + F A+GFGA++ + +PL + + G+ GV+NAY LQN+ L GPT F+P+I +V N A++ + Y +LLI+TDG + D T VI AS LP+SII++GVG F M LD D LL+ + A RD VQFV MR FL + G N LA+EVL E+P+QL YM + P
Sbjct: 79 DLNPQFKTTFLIPYFFEETQLFRFELYDVDSPKVGADMSGHDFLGRFECVLAQIVSYSTLRAHLGGKHSI------GAQWKNKDKVSKNGSITIRAEEDEKNEKIQFDVCGEKLDRKDFFGKSDPYLNFKRRFDDGSSHMIHQTEVKPKTLNPRWSTVLISTQALCGKNMDRPIIIECYDHEKFKKQ--------DDIIGT----AQTTLNTLIEQAGGGESTQIPLINEKKKLKKGAKYKNSGMLKIWNAKLVLEPTFLDFIAGGTQLDFAVAVDFTASNGNPRTPGSLHYMATGIPNQYEIALRSVLTICQHYNSSKTFEAYGFGAKLPNHQTVSAVFPLDLNRQSSSVVGINGVMNAYRHALQNVTLYGPTNFSPIIVEVANKAQKMMKTTARYQILLIITDGIISDMYATINTVINASGLPLSIIIIGVGNEDFERMHELDSDDALLQQDSRIAERDIVQFVTMRDFLGNQSGGYLNTDTIMENLAREVLYEVPDQLTGYMKRRGFTP 572
BLAST of Copine-3 vs. Ensembl Celegans
Match: gem-4 (Gon-2 Extragenic Modifier [Source:UniProtKB/TrEMBL;Acc:Q22422]) HSP 1 Score: 263.462 bits (672), Expect = 2.444e-78 Identity = 178/512 (34.77%), Postives = 273/512 (53.32%), Query Frame = 1
Query: 211 DQNPIFKCQLNLDYFFEEKQCIKVEIFGL------AKDSKISKIGCAESTIGRVI-------HSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCK-ENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQE------RKFELIN-SRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGS-HYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
D NP FK + YFFEE Q + E++ + A S +G E + +++ H GG+ + + N + S +R + D K E I+ + G LD+KD FGKSDPY+ ++ + G +++E+ TLNP W ++++S + LC KN+ I ++C+D + K D+IIG A+ L I++ + LIN +K KK Y NSG++ + ++ + +F+D++ GGT L+F VA+D T+SNG+ P SLH++ N+Y IA+++VL I Q Y++ + F A+GFGA++ + +PL + + G+ GV+NAY LQN+ L GPT F+P+I +V N A++ + Y +LLI+TDG + D T VI AS LP+SII++GVG F M LD D LL+ + A RD VQFV MR FL + G N LA+EVL E+P+QL YM + P
Sbjct: 79 DLNPQFKTTFLIPYFFEETQLFRFELYDVDSPKVGADMSGHDFLGRFECVLAQIVSYSTLRAHLGGKHSI------GAQWKNKDKVSKNGSITIRAEEDEKNEKIQFDVCGEKLDRKDFFGKSDPYLNFKRRFDDGSSHMIHQTEVKPKTLNPRWSTVLISTQALCGKNMDRPIIIECYDHEKFKKQ--------DDIIGT----AQTTLNTLIEQAGGGESTQIPLINEKKKLKKGAKYKNSGMLKIWNAKLVLEPTFLDFIAGGTQLDFAVAVDFTASNGNPRTPGSLHYMATGIPNQYEIALRSVLTICQHYNSSKTFEAYGFGAKLPNHQTVSAVFPLDLNRQSSSVVGINGVMNAYRHALQNVTLYGPTNFSPIIVEVANKAQKMMKTTARYQILLIITDGIISDMYATINTVINASGLPLSIIIIGVGNEDFERMHELDSDDALLQQDSRIAERDIVQFVTMRDFLGNQSGGYLNTDTIMENLAREVLYEVPDQLTGYMKRRGFTP 572
BLAST of Copine-3 vs. Ensembl Celegans
Match: nra-1 (Nicotinic receptor-associated protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XUB9]) HSP 1 Score: 254.988 bits (650), Expect = 3.421e-75 Identity = 176/509 (34.58%), Postives = 265/509 (52.06%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFG---------LAKDSKISKIGC------AESTIGRVIHSGGELFLQI-NVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDG-AKGDPEDMDNEF--DEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSN-SGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYC-DGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F L YFFEE Q ++ EI+ L+ + + C + ST+ + G++ Q N DK+ G+ Y ED E I+ + G LDKKD FGKSDPY+ +K + G +R+E+ TL+P W ++ ++ + LC K+ I ++C+D D KG+ D +F D++IG E L + L N +KK KK SG + + +++ + +F+D++ GGT L+F VA+D T+SNG SSLHF+ + N+Y +A+++VL I Q Y++ + F AFGFGA++ + +PL G+ GV+ AY L N++L GPT FAP+I V A+ D + Y +LLI+TDG + D T +++I AS LP+SII++GVG F M LD D LL+ + A RD VQFV MR+FL + + LA+EVL E+P QL YM + +P
Sbjct: 80 NPQFTKTFLLPYFFEETQLLRFEIYDADSPTVGQDLSSHDFLGRFECVLAQIVSYSTLKAHLGKTGQIGAQWRNKDKNTKTGS-------ITIYAEEDEKA-EKIQFDVCGEGLDKKDFFGKSDPYLNFKRKFDDGSTHLIHRTEVKPKTLDPRWATVQINTQTLCAKDGDRPIIIECYDHDKWKKGEEPRGDAKFSRDDLIGTAQTTLNELLRGSSDAVEILLTNEKKKAKKGDKYKCSGTLKIWNSRIVIEPTFLDFISGGTQLDFAVAVDFTASNGPPKSSSSLHFMSADRPNQYELALRSVLSICQHYNSSKTFEAFGFGAKLPNQSSVSAIFPLDLQRGTSEVVGITGVMTAYRHALSNVQLYGPTNFAPIIENVARKAQNMIHDSARYQILLIITDGIISDMHATIRSIISASGLPLSIIIIGVGNEDFEKMHELDSDDALLQQDSRIAQRDIVQFVTMREFLNNGQGLYLDPDVIQENLAREVLYEVPAQLTGYMKQRGFQP 580
BLAST of Copine-3 vs. Ensembl Celegans
Match: nra-1 (Nicotinic receptor-associated protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XUB9]) HSP 1 Score: 251.521 bits (641), Expect = 5.218e-74 Identity = 173/506 (34.19%), Postives = 260/506 (51.38%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFG---------LAKDSKISKIGC------AESTIGRVIHSGGELFLQI-NVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSN-SGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYC-DGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F L YFFEE Q ++ EI+ L+ + + C + ST+ + G++ Q N DK+ G+ Y ED E I+ + G LDKKD FGKSDPY+ +K + G +R+E+ TL+P W ++ ++ + LC K+ I ++C+D D K D ++IG E L + L N +KK KK SG + + +++ + +F+D++ GGT L+F VA+D T+SNG SSLHF+ + N+Y +A+++VL I Q Y++ + F AFGFGA++ + +PL G+ GV+ AY L N++L GPT FAP+I V A+ D + Y +LLI+TDG + D T +++I AS LP+SII++GVG F M LD D LL+ + A RD VQFV MR+FL + + LA+EVL E+P QL YM + +P
Sbjct: 80 NPQFTKTFLLPYFFEETQLLRFEIYDADSPTVGQDLSSHDFLGRFECVLAQIVSYSTLKAHLGKTGQIGAQWRNKDKNTKTGS-------ITIYAEEDEKA-EKIQFDVCGEGLDKKDFFGKSDPYLNFKRKFDDGSTHLIHRTEVKPKTLDPRWATVQINTQTLCAKDGDRPIIIECYDHDKWKKD---------DLIGTAQTTLNELLRGSSDAVEILLTNEKKKAKKGDKYKCSGTLKIWNSRIVIEPTFLDFISGGTQLDFAVAVDFTASNGPPKSSSSLHFMSADRPNQYELALRSVLSICQHYNSSKTFEAFGFGAKLPNQSSVSAIFPLDLQRGTSEVVGITGVMTAYRHALSNVQLYGPTNFAPIIENVARKAQNMIHDSARYQILLIITDGIISDMHATIRSIISASGLPLSIIIIGVGNEDFEKMHELDSDDALLQQDSRIAQRDIVQFVTMREFLNNGQGLYLDPDVIQENLAREVLYEVPAQLTGYMKQRGFQP 568
BLAST of Copine-3 vs. Ensembl Celegans
Match: cpna-5 (Copine family protein 5 [Source:UniProtKB/Swiss-Prot;Acc:Q09219]) HSP 1 Score: 145.591 bits (366), Expect = 3.557e-36 Identity = 143/508 (28.15%), Postives = 236/508 (46.46%), Query Frame = 1
Query: 214 QNPIFKCQLNLDYFFEEKQCIKVEIFGLAKD---SKISKIGCAESTIGRVIHSGGELFLQI--------NVDKDLSYGNNESHSPICIFYVREDSDCKEN-IEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGK----LVKTYRSEIIKNTLNPDWRSIMVSVEKLC-NKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSG-IVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENS-SNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFS-NPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLA-KQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNL 1674
+N +F + + Y FE+ Q IK +F D S ++I +V G LQ+ N+ LS + + V + KE I ++ G +LD+KD + E GK LV Y SE +KN +P W + + N+N EI+V D DG +G IG+F + Y + + +IN KK +KK Y NSG + V+ VS SF+DY+ GT L+F + +D +S P +H +D+ E +AI+A+ I+++Y + LF AFG GA++ P F +E+ L +FS +P C G++GV+ AY + + + +PVI V ++ + G HY VL + T G V D E ++A+ AS P+SI+++G+G F ++ L + RD VQF+ ++ L +G++ +K +A+ L +P+ ++ YM+ N+
Sbjct: 110 RNIVFTDKFSYQYVFEKTQLIKA-VFSRCHDRDKPSSSSRDILATSIFKVDELIGSFGLQLRRQLEKNGNIASALSGTQRVTDEYLGGIIVSAEMPEKEQPIVVQFHGKSLDRKDFLWDETAVFFRVFRLEEGKDDDSLVFLYESEALKNHSHPQWAEFRLDTQDAADNRNRLLEIWVMYKDVDGKEG-----------YIGKFLTTYAKMKYGPGSDNVYSVINDVKKAQKKSYENSGKMELVKFTDVSF-YSFLDYIVSGTQLHFEIGVDFSS-------PEPVHELDQRRFDGELHMAIRAIGSIIRDYTPNRLFAAFGIGAKIPPTFHESNEFFL--NFSMDPICRGLDGVMEAYRKTQTMVTPLKESKLSPVINYVTRMSHRSGFRGLHYHVLALFTRGEVTDLKEIQQALNSASDAPLSILIIGMGDFDFSSLQKLCSK-------RKDGRRDVVQFIHLKSLL----NGAEAPWLNKSRIAETALRHVPQHMVQYMHNANI 584
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne8 (copine VIII [Source:ZFIN;Acc:ZDB-GENE-100809-1]) HSP 1 Score: 358.221 bits (918), Expect = 1.190e-114 Identity = 203/501 (40.52%), Postives = 308/501 (61.48%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKPIGENKSLLS 1707
NP F + LDYFFEE+Q ++ +++ L +K +SK +G T+G V+ S G +++ L G + I E +C+E++ ++ G LDKKD FGKSDP+++ Y+ NE G +++E++KNTL+P W++ + V LCN + I ++ +DWD G + IGEFS +E + Q +E++N +KKKKKK Y NSG VT+ + + + +F+DY+ GGT +NF VAID T+SNG+ P+SLH++ N Y++A++AV EI+Q+YD+D+LFPA GFGA++ PD ++ HE+PL G+ NP+C G+EGV+ AY++ L++++L GPTYF+PVI V A DGS YF+LLI++DG + D +TK++++ AS LP+SII+VGVG +F +M LD D + A RD VQFVP R ++ D N S LAK+VLAE+P+Q L Y+ +KP S +S
Sbjct: 77 NPDFVHKFILDYFFEERQNLRFDLYDLDSKSENLSKHDFLGQMYCTLGEVVGSPGS-----RMERSL-IGIPGKNCGTVIVKAEELGNCRESVLMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRAIKIEVYDWDRDGGH---------DYIGEFSTSYRELSKGHTQFTVWEVLNPKKKKKKKKYLNSGTVTLLSCFIDVEVTFLDYIKGGTQINFTVAIDFTASNGNPSQPTSLHYMSPYHLNAYALALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPDNPYCSGIEGVLEAYYQSLKSVRLYGPTYFSPVINHVARYASLVKDGSEYFILLIISDGVISDMAQTKESIVNASSLPMSIIIVGVGPAEFDEMIELDGDEVRISSRGRFAERDIVQFVPFRDYI----DRRGNHILSMARLAKDVLAEIPDQFLQYVRSRGIKPQHSAHSTIS 558
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5b (copine Vb [Source:ZFIN;Acc:ZDB-GENE-040426-1398]) HSP 1 Score: 353.214 bits (905), Expect = 5.488e-113 Identity = 196/491 (39.92%), Postives = 302/491 (61.51%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + +K +SK +G T+G ++ S ++K L G + + + E +C+++ ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KKK Y NSG VT+ + V +++F+DY+ GGT +NF VAID T+SNG+ +SLH+++ N Y++A++AV EI+Q+YD+D++FPA GFGA++ PD ++ HE+PL G+ NP+C+G+EG++ AYH+ L+ ++L GPT FAPV+ V A DGS YF+LLI+TDG + D +TK+A++ A+ LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LAK+VLAE+P+Q + YM +K
Sbjct: 73 NPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQMFCTLGEIVGSPAS-----RLEKPLG-GISGKNCGTIVLSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYALALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFILLIITDGVISDMSQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSRGIK 544
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5a (copine Va [Source:ZFIN;Acc:ZDB-GENE-081105-9]) HSP 1 Score: 351.673 bits (901), Expect = 2.803e-112 Identity = 198/492 (40.24%), Postives = 301/492 (61.18%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F + LDYFFEEKQ ++ +I+ + +K ++K +G T+G ++ S G ++K L G + I E +C++ ++ LDKKD FG+SDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KK+ Y NSG VT+ + V +++F+DY+ G ++F VAID T+SNG+ +SLH+++ N Y++A++AV EI+Q+YD+D++FPA GFGA++ PD ++ HE+PL G+ NP+C+G+EG++ AYHE L+ ++L GPT FAPVI V A DGS YFVLLI+TDG + D +TK+A++ A+ LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LAK+VLAE+P+QL+ YM +KP
Sbjct: 73 NPDFVRKYILDYFFEEKQNLRFDIYDIDSKSPDLAKHDFLGQTFCTLGEIVGSPGS-----RLEKPLG-GIPGKNCGTIILTAEELGNCRDCATMQFCANKLDKKDFFGRSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPIWQPFTIPVRALCNGDYDRSIKVEVYDWD------RDGSHDF---IGEFTTSYRELSRGQSQFNVYEVVNPKKKLKKRRYINSGTVTLLSFLVEAEHTFLDYIKAGLQIHFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNVDNPYCNGMEGILEAYHESLKTVQLYGPTNFAPVINHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQLILYMKSRGIKP 545
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5b (copine Vb [Source:ZFIN;Acc:ZDB-GENE-040426-1398]) HSP 1 Score: 350.903 bits (899), Expect = 7.948e-112 Identity = 196/497 (39.44%), Postives = 302/497 (60.76%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---------IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + +K +SK +G T+G ++ S ++K L G + + + E +C+++ ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KKK Y NSG VT+ + V +++F+DY+ GGT +NF VAID T+SNG+ +SLH+++ N Y++A++AV EI+Q+YD+D++FPA GFGA++ PD ++ HE+PL G+ NP+C+G+EG++ AYH+ L+ ++L GPT FAPV+ V A DGS YF+LLI+TDG + D +TK+A++ A+ LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LAK+VLAE+P+Q + YM +K
Sbjct: 78 NPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHKPLELYDFLGQMFCTLGEIVGSPAS-----RLEKPLG-GISGKNCGTIVLSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYALALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFILLIITDGVISDMSQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSRGIK 555
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne1 (copine I [Source:ZFIN;Acc:ZDB-GENE-030131-3562]) HSP 1 Score: 337.806 bits (865), Expect = 1.892e-107 Identity = 210/546 (38.46%), Postives = 318/546 (58.24%), Query Frame = 1
Query: 85 KVIVGIGCLNLPDTFLSYYAE-FSVATGGYIHDK--DVMKTENQTD-QNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDS----KISKIGCAESTIGRVIHSGG-ELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAK---QYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLK-VGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKPI 1683
KV + I C NL D + ++ V DK +V +TE + Q+P F +L++DY+FE+ Q +K ++ + S +G E T+G+++ S LQ+ K G I E+ I ++++ NLDKKDLFGKSDP++ +K++E GK +R+E+IKN LNP W+ VS+ CN +L I V C+D D ED ++ +IGEF+ + + +F+ I+ K+KKKK Y NSG++ ++ ++ SF+DY+ GG +NF V ID T SNGD P SLH+++ N N+Y AI +V +++Q+YD+D+LFPAFGFGA+V P+F++ HE+PL + ++P+C GVEG++NAY VL ++L GPT F+P+I V +A Q + + YFVLLI+TDG + D +T+++++ +S LP+SII+VGVG F M+ LD D G+LK + E A RD VQFVP ++F K ALA+ VLAE+P QL+ Y NL P+
Sbjct: 8 KVELSISCNNLLDKDVGSKSDPLCVLLQSVGDDKWTEVARTERVKNCQDPQFSTKLHIDYYFEKVQKLKFGVYDIDNKSVDLGDDDFLGGFEGTLGQIVSSRKLTRPLQLKAAKPAGKGT--------ITITAEEVKDNRAIVMEIEAKNLDKKDLFGKSDPFLEFFKQDEDGKWQLVHRTEVIKNNLNPSWKKFTVSLHTFCNGDLNKPIKVTCYDKD------EDTSSD---MIGEFTCTTAKLMEAKDNAVEFDCIHPEKQKKKKSYKNSGVIKIKDCKLETQYSFLDYVMGGCQINFTVGIDFTGSNGDPRSPDSLHYLNPNGVNQYLSAIWSVGQVVQDYDSDKLFPAFGFGAQVPPNFQVSHEFPLNFNPNSPYCQGVEGIVNAYRSVLPQLRLYGPTNFSPIINHVARIASGAAQQPNAAQYFVLLIITDGEITDLDQTRQSIVNSSKLPMSIIIVGVGEADFKAMEFLDGDNGVLKSITGESAVRDIVQFVPFKQF----------ANAPKEALAQSVLAEVPSQLVTYFKMRNLPPV 526
BLAST of Copine-3 vs. Ensembl Xenopus
Match: acot11 (acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GENE-5864266]) HSP 1 Score: 363.614 bits (932), Expect = 8.233e-117 Identity = 211/493 (42.80%), Postives = 302/493 (61.26%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK----IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F + LDYFFEEKQ ++ ++F + ++ ISK +G A T+G VI S + ++K L+ G I E S+C++ + +++ LDKKD FGKSDP+++ Y+ NE G +++E+IKNTLNP W+ + V LCN + + V +DWD +G D IGEF+ +E Q +E++N +KK KKK Y NSG VT+ + + + +F+DY+ GGT LNF VAID T+SNG+ P+SLH+++ N Y +A++AV EI+Q+YD+D+LFPA+GFGA++ PD KI HE+ L GD NP C G++GV+ AY + L+ ++L GPT FA VI QV A DGS Y+VLLI+TDG + D ++TK+A++ AS LP+SII+VGVG +F M+ LD D + A RD VQFVP R ++ D S N S LAK+VLAE+PEQ L YM ++KP
Sbjct: 67 NPDFVRKFVLDYFFEEKQNLRFDVFNVDSRSCNISKHKDFLGQAFCTLGEVIGSP-----RSRLEKPLT-GIPGKKCGTIILSAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVYDWD--RGGSHDF-------IGEFTTSYRELSRGQSQFSVYEVLNPKKKCKKKKYINSGTVTLLSFKAESEYTFVDYIKGGTQLNFTVAIDFTASNGNPSQPTSLHYMNPYQLNAYGMALKAVGEIIQDYDSDKLFPAYGFGAKIPPDGKISHEFALNGDIENPNCVGIQGVLEAYFKSLRTVQLYGPTNFASVINQVARAAGDVTDGSQYYVLLIITDGVISDMVQTKEAIVNASSLPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRFAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQFLSYMKSRDIKP 540
BLAST of Copine-3 vs. Ensembl Xenopus
Match: cpne9 (copine family member IX [Source:NCBI gene;Acc:100125077]) HSP 1 Score: 362.459 bits (929), Expect = 4.143e-116 Identity = 209/511 (40.90%), Postives = 305/511 (59.69%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHS-------------------PICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F + LDYFFEEKQ ++ +++ + AK +SK +G T+G ++ S G ++K L G N +S I I E S+C++ ++ LDKKD FGKSDP+++ Y+ NE G +++E +KNTL+P W+ + V LCN + I V+ +DWD D ++F IGEFS +E Q +E+IN RKK KKK Y NSG VT+ + V + +F+DY+ GGT +NF VAID T+SNG+ +SLH+++ N Y++A++AV EI+Q+YD+D+ FPA GFGA++ PD ++ HE+PL G NP C+G+EG++ AYH+ L++++L GPT FAPV+ +V A DGSHYFVLLI+TDG + D +TK+A++ A+ LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LAK+VLAE+P+QL+ YM +KP
Sbjct: 67 NPDFVRKFVLDYFFEEKQNLRFDLYDVDAKSPDLSKHDFLGQCFCTLGEIVGSAGS-----RLEKSLIIGQNAPNSRSGRSTQSMSNGGIPSKKCGIIIISAEELSNCRDIATVQFSAHKLDKKDFFGKSDPFMVFYRSNEDGTYTICHKTEYVKNTLSPVWQKFSIPVRGLCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFSTSYRELSKGQSQFNIYEVINPRKKIKKKKYINSGTVTLLSFSVESEYTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQLNAYALALKAVGEIIQDYDSDKRFPALGFGAKLPPDGRVSHEFPLNGSIENPQCNGIEGILEAYHKSLKSVQLYGPTNFAPVVNRVARFAAAVQDGSHYFVLLIITDGVISDMSQTKEAIVNAAMLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLAKDVLAEIPDQLISYMKARGIKP 559
BLAST of Copine-3 vs. Ensembl Xenopus
Match: cpne9 (copine family member IX [Source:NCBI gene;Acc:100125077]) HSP 1 Score: 358.221 bits (918), Expect = 1.412e-114 Identity = 208/513 (40.55%), Postives = 302/513 (58.87%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAK-DSKISK-----IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHS-------------------PICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F + LDYFFEEKQ ++ ++F + D S +G T+G ++ S G ++K L G N +S I I E S+C++ ++ LDKKD FGKSDP+++ Y+ NE G +++E +KNTL+P W+ + V LCN + I V+ +DWD D ++F IGEFS +E Q +E+IN RKK KKK Y NSG VT+ + V + +F+DY+ GGT +NF VAID T+SNG+ +SLH+++ N Y++A++AV EI+Q+YD+D+ FPA GFGA++ PD ++ HE+PL G NP C+G+EG++ AYH+ L++++L GPT FAPV+ +V A DGSHYFVLLI+TDG + D +TK+A++ A+ LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LAK+VLAE+P+QL+ YM +KP
Sbjct: 62 NPDFVRKFVLDYFFEEKQNLRFDLFAITYFDLNFSLFLFDFLGQCFCTLGEIVGSAGS-----RLEKSLIIGQNAPNSRSGRSTQSMSNGGIPSKKCGIIIISAEELSNCRDIATVQFSAHKLDKKDFFGKSDPFMVFYRSNEDGTYTICHKTEYVKNTLSPVWQKFSIPVRGLCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFSTSYRELSKGQSQFNIYEVINPRKKIKKKKYINSGTVTLLSFSVESEYTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQLNAYALALKAVGEIIQDYDSDKRFPALGFGAKLPPDGRVSHEFPLNGSIENPQCNGIEGILEAYHKSLKSVQLYGPTNFAPVVNRVARFAAAVQDGSHYFVLLIITDGVISDMSQTKEAIVNAAMLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLAKDVLAEIPDQLISYMKARGIKP 556
BLAST of Copine-3 vs. Ensembl Xenopus
Match: acot11 (acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GENE-5864266]) HSP 1 Score: 350.517 bits (898), Expect = 3.004e-112 Identity = 209/492 (42.48%), Postives = 297/492 (60.37%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F + LDYFFEEKQ ++ ++F + ++ ISK +G A T+G VI S + ++K L+ G I E S+C++ + +++ LDKKD FGKSDP+++ Y+ NE G +++E+IKNTLNP W+ + V LCN + + V +DWD +G D IGEF+ +E Q +E++N +KK KKK Y NSG VT + S +F+ + F T LNF VAID T+SNG+ P+SLH+++ N Y +A++AV EI+Q+YD+D+LFPA+GFGA++ PD KI HE+ L GD NP C G++GV+ AY + L+ ++L GPT FA VI QV A DGS Y+VLLI+TDG + D ++TK+A++ AS LP+SII+VGVG +F M+ LD D + A RD VQFVP R ++ D S N S LAK+VLAE+PEQ L YM ++KP
Sbjct: 33 NPDFVRKFVLDYFFEEKQNLRFDVFNVDSRSCNISKHDFLGQAFCTLGEVIGSP-----RSRLEKPLT-GIPGKKCGTIILSAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVYDWD--RGGSHDF-------IGEFTTSYRELSRGQSQFSVYEVLNPKKKCKKKKYINSGTVTEELDGDSAI-TFLSFFFSRTQLNFTVAIDFTASNGNPSQPTSLHYMNPYQLNAYGMALKAVGEIIQDYDSDKLFPAYGFGAKIPPDGKISHEFALNGDIENPNCVGIQGVLEAYFKSLRTVQLYGPTNFASVINQVARAAGDVTDGSQYYVLLIITDGVISDMVQTKEAIVNASSLPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRFAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQFLSYMKSRDIKP 504
BLAST of Copine-3 vs. Ensembl Xenopus
Match: acot11 (acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GENE-5864266]) HSP 1 Score: 344.739 bits (883), Expect = 2.816e-110 Identity = 206/488 (42.21%), Postives = 290/488 (59.43%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKIGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F + LDYFFEEKQ ++ + F +G A T+G VI S + ++K L+ G I E S+C++ + +++ LDKKD FGKSDP+++ Y+ NE G +++E+IKNTLNP W+ + V LCN + + V +DWD +G D IGEF+ +E Q +E++N +KK KKK Y NSG VT + S +F+ + F T LNF VAID T+SNG+ P+SLH+++ N Y +A++AV EI+Q+YD+D+LFPA+GFGA++ PD KI HE+ L GD NP C G++GV+ AY + L+ ++L GPT FA VI QV A DGS Y+VLLI+TDG + D ++TK+A++ AS LP+SII+VGVG +F M+ LD D + A RD VQFVP R ++ D S N S LAK+VLAE+PEQ L YM ++KP
Sbjct: 33 NPDFVRKFVLDYFFEEKQNLRFDDF----------LGQAFCTLGEVIGSP-----RSRLEKPLT-GIPGKKCGTIILSAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVYDWD--RGGSHDF-------IGEFTTSYRELSRGQSQFSVYEVLNPKKKCKKKKYINSGTVTEELDGDSA-ITFLSFFFSRTQLNFTVAIDFTASNGNPSQPTSLHYMNPYQLNAYGMALKAVGEIIQDYDSDKLFPAYGFGAKIPPDGKISHEFALNGDIENPNCVGIQGVLEAYFKSLRTVQLYGPTNFASVINQVARAAGDVTDGSQYYVLLIITDGVISDMVQTKEAIVNASSLPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRFAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQFLSYMKSRDIKP 490
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne9 (copine family member IX [Source:MGI Symbol;Acc:MGI:2443052]) HSP 1 Score: 360.533 bits (924), Expect = 7.325e-116 Identity = 203/491 (41.34%), Postives = 301/491 (61.30%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK----IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + + ISK +G A +G VI G V++ L+ G + E S+C++ +++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + + + +DWD D ++F IGEF+ +E Q +E++N RKK KKK Y+NSG VT+ + V + +F+DY+ GGT LNF VAID T+SNG+ P+SLH++ + Y++A++AV EI+Q+YD+D+LFPA+GFGA++ P+ +I H++PL + +P C G+EGV+ +Y + L+ ++L GPTYFAPVI QV A + DGS Y+VLLI+TDG + D +TK+A++ AS LP+SII+VGVG F M+ LD D + A RD VQFVP R ++ D S N S LAK+VLAE+PEQLL YM +++
Sbjct: 64 NPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQGS-----RVERPLT-GVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWD------RDGSHDF---IGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQ 535
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne8 (copine VIII [Source:MGI Symbol;Acc:MGI:1914121]) HSP 1 Score: 350.903 bits (899), Expect = 7.088e-112 Identity = 203/491 (41.34%), Postives = 299/491 (60.90%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEE++ ++ +++ + +K +SK +G T+G ++ S G + V G I E + C++ + ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W++ +SV LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KKK Y+NSG VT+ + V + SF+DY+ GGT +NF VAID T+SNG+ P+SLH+++ N Y +A++AV EI+Q+YD+D++FPA GFGA++ PD +I HE+ L G+ NP+C G+EGV+ AY+ L++++L GPT FAPVI V A DGS YFVLLI+TDG + D +TK++++ AS LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D S N S LAK+VLAE+PEQ L YM +K
Sbjct: 87 NPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIV------GIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELARGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIK 558
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne5 (copine V [Source:MGI Symbol;Acc:MGI:2385908]) HSP 1 Score: 343.969 bits (881), Expect = 6.325e-109 Identity = 200/509 (39.29%), Postives = 302/509 (59.33%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYG----NNESHSPI---------------CIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNL 1674
NP F + +DYFFEEKQ ++ +++ + +K +SK +G A T+G ++ S G ++K L+ G N+ + P+ I E S+C++ ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W++ + V LCN + I V+ +DWD D ++F IGEF+ +E Q +E+IN +KK KKK Y NSG VT+ + V +++F+DY+ GGT +NF VAID T+SNG+ +SLH++ N Y++A+ AV EI+Q YD+D++FPA GFGA++ PD ++ HE+PL G+ NP C G++G++ AYH L+ ++L GPT FAPV+ V A DGS Y VLLI+TDG + D +TK+A++ A+ LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LA++VLAE+P+QL+ YM +
Sbjct: 73 NPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGS-----RLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELARGQSQFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEIPDQLVSYMKAQGI 563
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne2 (copine II [Source:MGI Symbol;Acc:MGI:2387578]) HSP 1 Score: 313.153 bits (801), Expect = 1.080e-97 Identity = 198/500 (39.60%), Postives = 289/500 (57.80%), Query Frame = 1
Query: 193 KTENQTDQ-NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKIGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINL--AKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKV-GNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
+TE + NP F + LDY FEE Q +K +F K S +G+ S G + + + L N++ I ++ I + + G LDKKDLFGKSDP++ YK + GK + +R+E+IK TL+P W+ V + LC+ +L+ I V C+D+D G D EF + + S A++ + + E IN +K++KKK Y NSGI+ +R+ ++ ++ SF+DY+ GG L F V ID T+SNG+ DPSSLH+I+ +NEY AI AV +I+Q+YD+D++FPA GFGA++ PD+K+ HE+ + + +NPFC GV+G+ AY L +I+ GPT F+P++ V + YF+LLI+TDG + D ET+ AV++AS LP+SII+VGVG F M+ LD D L+ E+A RD VQFVP R+F R AA K LAK VLAELP+Q++ Y NL P
Sbjct: 63 RTETAVNNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSSAQLD---EHDFLGQFSCSLGTIVSSKKITRPLLLMNDKPAGKGVITIAAQELSDNRVITLSLAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDLEKPIQVMCYDYDSNGG--HDFIGEFQTSVLQMS-EARDGV-----PLEIECINPKKQRKKKSYKNSGIIILRSCKIHRNYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQQTATYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDNRRLRSHTGEEAARDIVQFVPFREF-RNAA---------KETLAKAVLAELPQQVVQYFKHKNLPP 541
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne2 (copine II [Source:MGI Symbol;Acc:MGI:2387578]) HSP 1 Score: 312.768 bits (800), Expect = 1.557e-97 Identity = 200/501 (39.92%), Postives = 291/501 (58.08%), Query Frame = 1
Query: 193 KTENQTDQ-NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKIGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINL---AKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKV-GNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
+TE + NP F + LDY FEE Q +K +F K S +G+ S G + + + L N++ I ++ I + + G LDKKDLFGKSDP++ YK + GK + +R+E+IK TL+P W+ V + LC+ +L+ I V C+D+D G D EF + + S A++ + + E IN +K++KKK Y NSGI+ +R+ ++ ++ SF+DY+ GG L F V ID T+SNG+ DPSSLH+I+ +NEY AI AV +I+Q+YD+D++FPA GFGA++ PD+K+ HE+ + + +NPFC GV+G+ AY L +I+ GPT F+P++ V A Q + YF+LLI+TDG + D ET+ AV++AS LP+SII+VGVG F M+ LD D L+ E+A RD VQFVP R+F R AA K LAK VLAELP+Q++ Y NL P
Sbjct: 63 RTETAVNNLNPAFSKKFVLDYHFEEVQKLKFALFDQDKSSAQLD---EHDFLGQFSCSLGTIVSSKKITRPLLLMNDKPAGKGVITIAAQELSDNRVITLSLAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDLEKPIQVMCYDYDSNGG--HDFIGEFQTSVLQMS-EARDGV-----PLEIECINPKKQRKKKSYKNSGIIILRSCKIHRNYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQQTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDNRRLRSHTGEEAARDIVQFVPFREF-RNAA---------KETLAKAVLAELPQQVVQYFKHKNLPP 542
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q5BJS7|CPNE9_RAT (Copine-9 OS=Rattus norvegicus OX=10116 GN=Cpne9 PE=2 SV=1) HSP 1 Score: 360.918 bits (925), Expect = 3.415e-115 Identity = 203/491 (41.34%), Postives = 301/491 (61.30%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK----IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + + ISK +G A +G VI G V++ L+ G + E S+C++ +++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + + + +DWD D ++F IGEF+ +E Q +E++N RKK KKK Y+NSG VT+ + V + +F+DY+ GGT LNF VAID T+SNG+ P+SLH++ + Y++A++AV EI+Q+YD+D+LFPA+GFGA++ P+ +I H++PL + +P C G+EGV+ +Y + L+ ++L GPTYFAPVI QV A + DGS Y+VLLI+TDG + D +TK+A++ AS LP+SII+VGVG F M+ LD D + A RD VQFVP R ++ D S N S LAK+VLAE+PEQLL YM +++
Sbjct: 64 NPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQGS-----RVERPLT-GVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWD------RDGSHDF---IGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQ 535
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q1RLL3|CPNE9_MOUSE (Copine-9 OS=Mus musculus OX=10090 GN=Cpne9 PE=1 SV=1) HSP 1 Score: 360.533 bits (924), Expect = 4.858e-115 Identity = 203/491 (41.34%), Postives = 301/491 (61.30%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK----IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + + ISK +G A +G VI G V++ L+ G + E S+C++ +++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + + + +DWD D ++F IGEF+ +E Q +E++N RKK KKK Y+NSG VT+ + V + +F+DY+ GGT LNF VAID T+SNG+ P+SLH++ + Y++A++AV EI+Q+YD+D+LFPA+GFGA++ P+ +I H++PL + +P C G+EGV+ +Y + L+ ++L GPTYFAPVI QV A + DGS Y+VLLI+TDG + D +TK+A++ AS LP+SII+VGVG F M+ LD D + A RD VQFVP R ++ D S N S LAK+VLAE+PEQLL YM +++
Sbjct: 64 NPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQGS-----RVERPLT-GVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWD------RDGSHDF---IGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQ 535
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q8IYJ1|CPNE9_HUMAN (Copine-9 OS=Homo sapiens OX=9606 GN=CPNE9 PE=1 SV=3) HSP 1 Score: 359.377 bits (921), Expect = 1.368e-114 Identity = 203/491 (41.34%), Postives = 300/491 (61.10%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK----IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + + ISK +G A +G VI G V++ L+ G + E S+C++ +++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + + + +DWD D ++F IGEF+ +E Q +E++N RKK KKK Y NSG VT+ + V + +F+DY+ GGT LNF VAID T+SNG+ P+SLH++ + Y++A++AV EI+Q+YD+D+LFPA+GFGA++ P+ +I H++PL + +P C G+EGV+ +Y + L+ ++L GPTYFAPVI QV A + DGS Y+VLLI+TDG + D +TK+A++ AS LP+SII+VGVG F M+ LD D + A RD VQFVP R ++ D S N S LAK+VLAE+PEQLL YM +++
Sbjct: 64 NPDFVRKFVLDYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGS-----RVERTLT-GVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWD------RDGSHDF---IGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQ 535
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q86YQ8|CPNE8_HUMAN (Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=2) HSP 1 Score: 350.903 bits (899), Expect = 3.873e-111 Identity = 203/491 (41.34%), Postives = 299/491 (60.90%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEE++ ++ +++ + +K +SK +G T+G ++ S G + V G I E + C++ + ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W++ +SV LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KKK Y+NSG VT+ + V + SF+DY+ GGT +NF VAID T+SNG+ P+SLH+++ N Y +A++AV EI+Q+YD+D++FPA GFGA++ PD +I HE+ L G+ NP+C G+EGV+ AY+ L++++L GPT FAPVI V A DGS YFVLLI+TDG + D +TK++++ AS LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D S N S LAK+VLAE+PEQ L YM +K
Sbjct: 74 NPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIV------GIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIK 545
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q9DC53|CPNE8_MOUSE (Copine-8 OS=Mus musculus OX=10090 GN=Cpne8 PE=2 SV=3) HSP 1 Score: 350.903 bits (899), Expect = 4.958e-111 Identity = 203/491 (41.34%), Postives = 299/491 (60.90%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEE++ ++ +++ + +K +SK +G T+G ++ S G + V G I E + C++ + ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W++ +SV LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KKK Y+NSG VT+ + V + SF+DY+ GGT +NF VAID T+SNG+ P+SLH+++ N Y +A++AV EI+Q+YD+D++FPA GFGA++ PD +I HE+ L G+ NP+C G+EGV+ AY+ L++++L GPT FAPVI V A DGS YFVLLI+TDG + D +TK++++ AS LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D S N S LAK+VLAE+PEQ L YM +K
Sbjct: 87 NPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIV------GIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELARGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIK 558
BLAST of Copine-3 vs. TrEMBL
Match: A0A4S2L3S0 (C2 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009940 PE=4 SV=1) HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0 Identity = 308/586 (52.56%), Postives = 403/586 (68.77%), Query Frame = 1
Query: 79 KPKVIVGIGCLNLPDTFLSYYAEFSVATGGYIHDKDVMKTENQTD-QNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK--IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP---IGENKSLLSATLDNSKLNAKEFVQQKLRRCATAYGMTKSNRQGSTD 1818
+P++ +GI C NLP YA+FSVA GG +H+K V +TE Q +NPIF +LNL+YFFEE+Q I EIF ++ + +G + T+GRVIHSGGEL L + + + + P +RED KENI +KMQGFNLDKKD FGKSDPYV +Y++NERGKL K YRSE+IKNTL PD+R I+V +++LC N+ E+ +CFDWDGA GD E++D E D++IGEF+ E L +F+LIN KKK+KK Y +SG + VR + + SF+DY+FGGT +N ++ +DL++ P+S S NEYS+AIQAV+EILQEYD+D+LFPA+GFG+R++ KICH+YPL+GD +N FC G+ GV+ AY + + LSGP F+P+IR V + A++ D +Y+VLLILT+GTVDDWIETKKAVIE SFLPISIIV+G+GGGKF DM+ LDQDFGLLKVG EQACRDNVQFV MR+FLR AADGSDN++WSKV LAKEVLAELP Q+LDY +++L P I LL +D A F Q + + + T Q ST+
Sbjct: 4 RPRIQIGISCTNLPTKLPGSYAKFSVAHGGTLHEKHVTETEIQRQTRNPIFLTRLNLEYFFEERQIITSEIFQCEREDREDSQLLGFGQCTVGRVIHSGGELELPLICNDEQKNLLDPGRPPSVFVCIREDPFSKENIYLKMQGFNLDKKDFFGKSDPYVTIYRRNERGKLQKAYRSEVIKNTLFPDFRPILVCLDRLCGGNVDCELCFRCFDWDGALGDSEEVDTELDDLIGEFTTTISELLRSDESGLEFKLINPPKKKRKKNYQDSGQLKVRLSLAQSNFSFLDYIFGGTSINVVIGVDLSNHISSKQMPASRQIEVAQSCNEYSVAIQAVMEILQEYDSDQLFPAYGFGSRLSSGGKICHKYPLSGDENNYFCKGMAGVLEAYRRSFEALHLSGPICFSPIIRDVSDTARRNKDTENYYVLLILTNGTVDDWIETKKAVIETSFLPISIIVIGIGGGKFADMEILDQDFGLLKVGQEQACRDNVQFVQMRRFLRLAADGSDNLRWSKVGLAKEVLAELPSQILDYFERNHLLPCHSIPGQPKLLKDLVDPGWWRA--FTQPDTSQVSEEFSTTVQTAQTSTE 587
BLAST of Copine-3 vs. TrEMBL
Match: A0A4Z2DGU0 (Copine-8 OS=Schistosoma japonicum OX=6182 GN=EWB00_001084 PE=4 SV=1) HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0 Identity = 294/539 (54.55%), Postives = 393/539 (72.91%), Query Frame = 1
Query: 79 KPKVIVGIGCLNLPDTFLSYYAEFSVATGGYIHDKDVMKTE-NQTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKI--GCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTS-SNGDIHDPSSLHFID-ENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
KP++ +GI C N+P + YA+FSV+ GGY+H++ V +TE + +P + ++NL+Y FEEKQ I EIF ++ + + I G + T+GRVIHSGGEL L I ++D+ + S S + +RED KENI IKM G NLDKKD FGKSDPYVI+Y++NERGKL K YRSE+IKNTL PDW+ I++ +++LC N+ E+Y +CFDWDGA GD ED+D E D++IGEF+ L +F+LIN KKK+KK Y NSG++TV+ SF+DY+FGG +N +VA+D++S ++ + +S I+ S EY +AIQAV+EILQEYD+D+LFPAFGFGA+V+ K+ H YPL GD +N +C G+ GV++AY L ++ SGP +FAP+IR+V AK+ +Y+VLLILT+GTVDDWI+TKKAVIE SFLPISIIV+GVGGGKF +M+ LDQDFGLLKVG EQACRDNVQFV MR+FLR AADGSD+++WSKVALAKEVLAELP Q+L+Y++K++L P
Sbjct: 4 KPRIQIGISCRNIPKLLKASYAKFSVSYGGYLHERHVTETELVYNNLSPNYTTRINLEYCFEEKQIITTEIFECEREDRENSILLGYIQCTVGRVIHSGGELILPIIWNEDVQV--DRSTSTDVVVCIREDPFSKENIFIKMNGANLDKKDFFGKSDPYVIIYRRNERGKLQKCYRSEVIKNTLFPDWKPILICLDRLCGGNIDCELYFRCFDWDGAVGDSEDVDTEIDDLIGEFNTTVSRLLNCNENGIEFQLINMPKKKRKKYYQNSGLLTVKLYFAQSKFSFLDYIFGGLSINVVVAVDMSSHASMNSTTSTSSQQIELSQSHTEYEVAIQAVMEILQEYDSDQLFPAFGFGAKVSSAGKLSHRYPLNGDVNNCYCKGMVGVLSAYRRCLTDLYSSGPIFFAPIIREVSEAAKRSEAADNYYVLLILTNGTVDDWIDTKKAVIETSFLPISIIVLGVGGGKFSEMEILDQDFGLLKVGQEQACRDNVQFVQMRRFLRLAADGSDSIRWSKVALAKEVLAELPSQILEYLDKNHLSP 540
BLAST of Copine-3 vs. TrEMBL
Match: A0A3Q0KS66 (Copine, putative OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 556.984 bits (1434), Expect = 0.000e+0 Identity = 292/539 (54.17%), Postives = 387/539 (71.80%), Query Frame = 1
Query: 79 KPKVIVGIGCLNLPDTFLSYYAEFSVATGGYIHDKDVMKTE-NQTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKI--GCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTS--SNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
KP++ +GI C N+P + YA+FSV+ GGY+H+K V +TE + +P + +LNL+Y FEEKQ I EIF ++ + + + G + T+GRVIHSGGEL L I ++D+ N S + +RED KENI IKM G NLDKKD FGKSDPYVI+Y++NERGKL K YRSE+IKNTL PDW+ I++ +++LC N+ E+Y +CFDWDGA GD ED+D E D++IGEF+ L +F+LIN KKK+KK Y NSG++TV+ SF+DY+FGG +N +VA+D+++ S I + S S EY +AIQAV+EILQEYD+D+LFPAFGFGA+V+ K+ H YPL + +N +C G+ GV++AY L ++ SGP F+P+IR+V AK+ +Y+VLLILT+GTVDDWIETKK+VIE SFLPISIIV+GVGGGKF +M+ LDQDFGLLKVG EQACRDNVQFV MR+FLR AADGSD+++WSKVALAKEVLAELP Q+L+Y++K++L P
Sbjct: 4 KPRIQIGISCRNIPKLLKASYAKFSVSYGGYLHEKHVTETELVYNNLSPNYTTRLNLEYCFEEKQIITTEIFECEREDRENSVLLGYIQCTVGRVIHSGGELILPITWNEDIQVDRNTSTE--VVVCIREDPFSKENIFIKMNGANLDKKDFFGKSDPYVIIYRRNERGKLQKCYRSEVIKNTLFPDWKPILICLDRLCGGNIDCELYFRCFDWDGAVGDSEDVDTEIDDLIGEFNTTVSRLLNSNENGIEFQLINMPKKKRKKCYQNSGLLTVKLYFAQSKFSFLDYIFGGLSINVVVAVDMSTHASMNSITNTPSQQIELSQSHTEYEVAIQAVMEILQEYDSDQLFPAFGFGAKVSSGGKLSHRYPLV-NVNNCYCKGMVGVLSAYRRCLTDLYSSGPILFSPIIREVSEAAKRSEAADNYYVLLILTNGTVDDWIETKKSVIETSFLPISIIVLGVGGGKFSEMEILDQDFGLLKVGQEQACRDNVQFVQMRRFLRLAADGSDSIRWSKVALAKEVLAELPSQILEYLDKNHLSP 539
BLAST of Copine-3 vs. TrEMBL
Match: A0A267G9Y0 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017750g6 PE=4 SV=1) HSP 1 Score: 556.984 bits (1434), Expect = 0.000e+0 Identity = 287/540 (53.15%), Postives = 378/540 (70.00%), Query Frame = 1
Query: 85 KVIVGIGCLNLPDTFLSYYAEFSVATGGYIHDKDVMKTEN-QTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK------IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSP-ICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
KV++G+ C +LP +A ++ +G Y+ +KD + TE NP + L Y FEE+Q I++EI A D S+ IG ++G +IHSGG L Q+ S SP +C +V E + KEN+ +K+ G LDKKDLFGKSDPY+I+ K+N++G+LV+ YR+E+IKNTL+PDW+ I VSV++LC +L+ EI +C+DWDGA+GD ED D EFDE IGEF+ KE +E FELIN RK KKKK Y NSG VT +T + D SF+DYMF GTDL F VAID+T+SNG P+SLH+ D + N+Y+IA+QAVLEI+Q+YD+D+L PAFGFG R PD+++ HE+PL GD +NPFC G GV+ AY L+ ++LSGPT+FAPVI+ V LA + DGS Y+VLLILTDGT+DDW E K+AVIEAS+LP+SIIVVG+G G F +M+ LDQD LL+ G ++ACRD VQFV +RK+LR AADGSD V+WSKVALAK+VL ELP Q+L+YM + LKP
Sbjct: 34 KVVIGVKCRDLP--VDRSFAVIALHSGSYMTEKDTVTTETVDKTHNPTYSIPLITSYKFEERQMIELEIH-CAMDDHSSRAASRKVIGSCTVSLGHLIHSGGSLDCQLC-----------SSSPAVCTIHVEEYAGNKENMLLKLNGRGLDKKDLFGKSDPYMIIDKRNDKGRLVRAYRTEVIKNTLDPDWKPIKVSVDRLCGGDLRREIRFRCYDWDGAEGDHEDKDIEFDEFIGEFATTPKELFSNDGREVTFELINPRKAKKKKNYRNSGTVTAKTIPIDADFSFLDYMFSGTDLCFTVAIDMTASNGSPSQPTSLHYTDPFTPNQYTIAMQAVLEIIQDYDSDQLLPAFGFGCRAPPDYRVSHEWPLNGDSANPFCQGAAGVLEAYRHCLEEVRLSGPTHFAPVIKHVSRLALNHQDGSRYYVLLILTDGTIDDWTECKRAVIEASYLPVSIIVVGIGSGNFTEMELLDQDVWLLEEGGQKACRDIVQFVELRKYLRVAADGSDGVRWSKVALAKDVLQELPSQILEYMRRRRLKP 559
BLAST of Copine-3 vs. TrEMBL
Match: A0A267FGY6 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017750g2 PE=4 SV=1) HSP 1 Score: 554.673 bits (1428), Expect = 0.000e+0 Identity = 286/540 (52.96%), Postives = 376/540 (69.63%), Query Frame = 1
Query: 85 KVIVGIGCLNLPDTFLSYYAEFSVATGGYIHDKDVMKTEN-QTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK------IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSP-ICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
KV++G+ C +LP +A ++ +G Y+ +KD + TE NP + L Y FEE+Q I++EI A D S+ IG ++G +IHSGG L Q+ S SP +C +V E + KEN+ +K+ G LDKKDLFGKSDPY+I+ K+N++G+LV+ YR+E+IKNTL+PDW+ I VSV++LC + EI +C+DWDGA+GD ED D EFDE IGEF+ KE +E FELIN RK KKKK Y NSG VT +T + D SF+DYMF GTDL F VAID+T+SNG P+SLH+ D + N+Y+IA+QAVLEI+Q+YD+D+L PAFGFG R PD+++ HE+PL GD +NPFC G GV+ AY L+ ++LSGPT+FAPVI+ V LA + DGS Y+VLLILTDGT+DDW E K+AVIEAS+LP+SIIVVG+G G F +M+ LDQD LL+ G ++ACRD VQFV +RK+LR AADGSD V+WSKVALAK+VL ELP Q+L+YM + LKP
Sbjct: 34 KVVIGVKCRDLP--VDRSFAVIALHSGSYMTEKDTVTTETVDKTHNPTYSIPLITSYKFEERQMIELEIH-CAMDDHSSRAASRKVIGSCTVSLGHLIHSGGSLDCQLC-----------SSSPAVCTIHVEEYAGNKENMLLKLNGRGLDKKDLFGKSDPYMIIDKRNDKGRLVRAYRTEVIKNTLDPDWKPIKVSVDRLCGGEFRREIRFRCYDWDGAEGDHEDKDIEFDEFIGEFATTPKELFSNDGREVTFELINPRKAKKKKNYRNSGTVTAKTIPIDADFSFLDYMFSGTDLCFTVAIDMTASNGSPSQPTSLHYTDPFTPNQYTIAMQAVLEIIQDYDSDQLLPAFGFGCRAPPDYRVSHEWPLNGDSANPFCQGAAGVLEAYRHCLEEVRLSGPTHFAPVIKHVSRLALNHQDGSRYYVLLILTDGTIDDWTECKRAVIEASYLPVSIIVVGIGSGNFTEMELLDQDVWLLEEGGQKACRDIVQFVELRKYLRVAADGSDGVRWSKVALAKDVLQELPSQILEYMRRRRLKP 559
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne5b (copine-5 [Source:NCBI gene;Acc:103046149]) HSP 1 Score: 353.599 bits (906), Expect = 3.824e-113 Identity = 199/491 (40.53%), Postives = 299/491 (60.90%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + +K +SK +G T+G ++ S +DK L G I E +C+++ ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+S + V LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KKK Y NSG VT+ + V + +F+DY+ GGT +NF VAID T+SNG+ +SLH+++ N Y++A++AV EI+Q+YD+D++FPA GFGA++ PD ++ HE+PL G+ NP+C+G+EG++ AYH+ L+ ++L GPT FAPV+ V A DGS YFVLLI+TDG + D +TK+A++ + LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LAK+VLAE+P+Q + YM +K
Sbjct: 78 NPDFVRKFILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQMFCTLGEIVGSPAS-----RLDKPLG-GIPGKKCGTIILSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQSFTIPVRALCNGDFDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMSQTKEAIVNGAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSRGIK 549
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne5b (copine-5 [Source:NCBI gene;Acc:103046149]) HSP 1 Score: 352.058 bits (902), Expect = 2.304e-112 Identity = 199/496 (40.12%), Postives = 299/496 (60.28%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK--------IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + +K +SK +G T+G ++ S +DK L G I E +C+++ ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+S + V LCN + I V+ +DWD D ++F IGEF+ +E Q +E++N +KK KKK Y NSG VT+ + V + +F+DY+ GGT +NF VAID T+SNG+ +SLH+++ N Y++A++AV EI+Q+YD+D++FPA GFGA++ PD ++ HE+PL G+ NP+C+G+EG++ AYH+ L+ ++L GPT FAPV+ V A DGS YFVLLI+TDG + D +TK+A++ + LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LAK+VLAE+P+Q + YM +K
Sbjct: 78 NPDFVRKFILDYFFEEKQNLRFDLYDVDSKSPDLSKHPSECNDFLGQMFCTLGEIVGSPAS-----RLDKPLG-GIPGKKCGTIILSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQSFTIPVRALCNGDFDRTIKVEVYDWD------RDGSHDF---IGEFTTSYRELARGQSQFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMSQTKEAIVNGAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSRGIK 554
BLAST of Copine-3 vs. Ensembl Cavefish
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498]) HSP 1 Score: 343.969 bits (881), Expect = 1.478e-109 Identity = 199/491 (40.53%), Postives = 297/491 (60.49%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEE+Q ++ +++ + +K S +SK +G A+ T+G ++ S G ++K L G I E ++C+E++ ++ G LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W++ + V LCN + S + IGEFS +E Q +E+IN +KK KKK Y NSG VT+ + V D +F+DY+ GGT +NF VAID T+SNG+ P+SLH++ N Y++A++AV EI+Q+YD+D++FPA GFGA++ PD ++ HE+ L G+ NP+C+G++GV+ AY++ L++++L GPT F+PVI V A DGS YFVLLI+TDG + D +TK++++ AS LP+SII+VGVG +F M LD D + A RD VQFVP R ++ D + N S LAK+VLAE+P+Q L YM +K
Sbjct: 80 NPEFVRKFILDYFFEERQNLRFDLYDVDSKSSNLSKHDFLGQAQCTLGEIVGSMGS-----RLEKPLG-GIPGKKCGTIIVKAEELNNCRESVMMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQAFKIPVRALCNGDYDSH-----------------------DFIGEFSTSYRELSRGQSQFNVYEVINPKKKGKKKKYLNSGTVTLLSFLVDIDVTFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMSPYQLNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFALNGNPQNPYCNGIDGVMEAYYQSLKSVQLYGPTNFSPVINHVARYAASVKDGSQYFVLLIITDGVISDMAQTKESIVNASCLPMSIIIVGVGPAEFDAMVELDGDEVRISSRGRYAERDIVQFVPFRDYI----DRTGNHILSMARLAKDVLAEIPDQFLSYMKTRGIK 537
BLAST of Copine-3 vs. Ensembl Cavefish
Match: CPNE9 (copine family member 9 [Source:HGNC Symbol;Acc:HGNC:24336]) HSP 1 Score: 331.643 bits (849), Expect = 5.193e-105 Identity = 199/495 (40.20%), Postives = 297/495 (60.00%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFI---VAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F + LD+FFEEKQ ++ +++ + + S ISK +G T+G +I S G +++ LS G IF E S+C++ +++ LDKKD FGKSDP+++ Y+ NE G +++E+IKNTLNP W+ + V LCN + + V FDWD D ++F IGEF+ +E Q +E++N +KK KKK Y NSG VT+ + +V + +F+D++ GG L+ + + +G+ P+SLH++ N Y++A++AV EI+Q+YD+D+LFPA+GFGA++ PD KI H +PL G+ +P C +EGV+ AY + L+ ++L GPT FAPVI QV A+ DGS YFVLL++TDG + D ++TK+AV+ AS LP+SII+VGVG +F M+ LD D + A RD VQFVP R ++ D S N S LAK+VLAE+P+QLL +M ++P
Sbjct: 54 NPDFVRKFVLDFFFEEKQNLRFDVYNVDTRSSNISKHDFLGQTFCTLGEIIGSTGS-----RMERTLS-GIPGKKCGNIIFTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVFDWD------RDGSHDF---IGEFTTSYRELSRGQSQFNVYEVLNPKKKGKKKKYVNSGTVTLLSFKVESEYTFVDFIRGGYSLDHTKIKCVPNPSLISGNPAQPTSLHYMSPYQMNTYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPDGKISHVFPLNGNSEDPNCVAIEGVLEAYFQSLRTVQLYGPTNFAPVINQVARSAQDVTDGSQYFVLLMITDGVISDMVQTKEAVVNASALPMSIIIVGVGPAEFDAMEELDGDDVRVSSRGRFAERDIVQFVPFRDYI----DRSGNQVLSMARLAKDVLAEIPDQLLSFMKSKGIEP 529
BLAST of Copine-3 vs. Ensembl Cavefish
Match: CPNE9 (copine family member 9 [Source:HGNC Symbol;Acc:HGNC:24336]) HSP 1 Score: 323.939 bits (829), Expect = 1.703e-102 Identity = 205/514 (39.88%), Postives = 301/514 (58.56%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKPIGENKSLLSA--TLDNSKLNAK 1740
NP F + LD+FFEEKQ ++ +++ + + S ISK +G T+G +I S G +++ LS G IF E S+C++ +++ LDKKD FGKSDP+++ Y+ NE G +++E+IKNTLNP W+ + V LCN + + V FDWD D ++F IGEF+ +E Q +E++N +KK KKK Y NSG VT+ + +V + + Y T + + L S G+ P+SLH++ N Y++A++AV EI+Q+YD+D+LFPA+GFGA++ PD KI H +PL G+ +P C +EGV+ AY + L+ ++L GPT FAPVI QV A+ DGS YFVLL++TDG + D ++TK+AV+ AS LP+SII+VGVG +F M+ LD D + A RD VQFVP R ++ D S N S LAK+VLAE+P+QLL +M ++P + LSA T + LNA+
Sbjct: 23 NPDFVRKFVLDFFFEEKQNLRFDVYNVDTRSSNISKHDFLGQTFCTLGEIIGSTGS-----RMERTLS-GIPGKKCGNIIFTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVFDWD------RDGSHDF---IGEFTTSYRELSRGQSQFNVYEVLNPKKKGKKKKYVNSGTVTLLSFKVESEYT---YSLDHTKIKCVPNPSLIS--GNPAQPTSLHYMSPYQMNTYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPDGKISHVFPLNGNSEDPNCVAIEGVLEAYFQSLRTVQLYGPTNFAPVINQVARSAQDVTDGSQYFVLLMITDGVISDMVQTKEAVVNASALPMSIIIVGVGPAEFDAMEELDGDDVRVSSRGRFAERDIVQFVPFRDYI----DRSGNQVLSMARLAKDVLAEIPDQLLSFMKSKGIEP----RPALSASGTPNKPPLNAR 508
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 325.479 bits (833), Expect = 2.921e-103 Identity = 204/507 (40.24%), Postives = 303/507 (59.76%), Query Frame = 1
Query: 184 DVMKTEN-QTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKIGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFS---IPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQY---CDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKV-GNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
+V +TE + P F +L ++Y FEE Q +K +F +D+ +K+ +G + + G++ + + L ++ I E+ I + M G LDK DLFGKSDPY+ +YK++ G + +R+E+++NTL+P W+ + ++ LCN +L+ I C+DWD G P+ +IGEF I KE ++ +FE IN++KK+KKK Y NSGI+ ++ ++S+D +F+DY+FGG L+F V ID T+SNG+ D SSLH+I N+Y AI AV +I+Q+YD D+LFPA GFGA++ PD K+ H++ L + SNPFC G+EG++ AYH LQNI+L GPT F+P+I V + A S Y+VLLI+TDG + D T++A+++AS LP+S+I+VGVG F M+ LD D +L E A RD VQFVP R+F + D K +K LAK VLAELP Q++ Y + NL P
Sbjct: 55 EVARTETIKNTLCPDFSRKLVMEYRFEEVQKLKFALFD--EDAPSAKL-VDHDFLGEITSTLGQIVSHRTLTRPLLMQDDRPAGRGTITISAEEITDNRIITLSMAGRKLDKMDLFGKSDPYLEIYKQSPDGTWMLVHRTEVVRNTLDPTWKPFTLHLQVLCNGDLEKNINAVCYDWD-RHGSPD--------LIGEFYANIIRLKE-ATGSMEVVEFECINNKKKQKKKSYKNSGIIICKSCKISRDYTFLDYIFGGCQLHFTVGIDFTASNGNPRDASSLHYISPTGMNDYLAAIWAVGQIIQDYDTDKLFPALGFGAQLPPDCKVHHDFALNFNPSNPFCTGIEGIVAAYHFCLQNIRLYGPTNFSPIINHVASFAHTASGSASASEYYVLLIITDGVISDMEATREAIVKASRLPMSVIIVGVGNADFEAMEVLDSDDRVLTAPSGEAATRDIVQFVPFRQFR--SVDRLLINKAAKEELAKSVLAELPGQVVQYFRQRNLSP 546
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007777.1 (pep scaffold:Pmarinus_7.0:GL477373:3581:22444:1 gene:ENSPMAG00000006999.1 transcript:ENSPMAT00000007777.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 249.98 bits (637), Expect = 7.983e-75 Identity = 172/481 (35.76%), Postives = 263/481 (54.68%), Query Frame = 1
Query: 154 VATGGYIHDKDVMKTEN-QTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKI------GCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTS--SNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINL---AKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKV-GNEQACRDNVQFVPMRKF 1557
+ GG + D +TE Q Q P F +L +DY FE+ Q ++ ++ + D+K + G E + +V+ S + + L N + I V ++ + +++ NLDKKD+FGKSDPY+ +K + G +R+E+IKN LNP WR + ++ LCN +L+ ++ V C+D+D D D +IGEF K + +F +I+ KKKKKK Y SG+V V++ + + SF+DY+ GG +NF V L S + GDIH + L + A+ + I + D+LFPAFGFGA++ P++++ HE+PL + +NP+C+GV+G+++ Y L ++L GPT F+P+I V A Q + YFVLLI+TDG + D ET+ AV++AS LP+S+I+VGVG F M+ LD D G+LK E A RD VQFVP R F
Sbjct: 66 IEAGGTWSEVD--RTEQIQNCQEPAFSKRLQIDYCFEQVQKLRFGVYDI--DNKTYDLTDDDFLGQLECNLAQVVSSK-------KMTRPLLLKNGKPAGKGQITIVADEIKDNRVLALQVDARNLDKKDMFGKSDPYLEFFKMADDGTWQMVHRTEVIKNNLNPTWRPFSIPLQALCNGDLERDVRVVCYDYDS--------DGSHD-LIGEFKTNVKNLQQAEKGQVEFAVIHPEKKKKKKNYKGSGLVIVKSCRTEVEYSFLDYIMGGCQINFTVRSALRSCLTLGDIHRINLLTLHIPWPLLPLNNALSSFNGIKSHHLQDKLFPAFGFGAQIPPNWQVSHEFPLNFNPANPYCNGVQGIVDMYKVCLPQVRLYGPTNFSPIINHVARFAAAALQQPAATQYFVLLIVTDGVISDMDETRLAVVQASRLPMSLIIVGVGNADFSAMEFLDGDGGVLKAPSGEPAARDIVQFVPFRDF 526
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000748.1 (pep scaffold:Pmarinus_7.0:GL477446:179420:193439:1 gene:ENSPMAG00000000673.1 transcript:ENSPMAT00000000748.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 233.417 bits (594), Expect = 2.672e-70 Identity = 145/395 (36.71%), Postives = 217/395 (54.94%), Query Frame = 1
Query: 517 KDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWD-GAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQER-KFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAK----QYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKV-GNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
+D FGKSDP++ +YK+ GK YR+E+ KNTLNP W++I+++++ LC+ N+ I V C DW+ + +P IGE + + + F+L+ K Y NSG + V + + +F+DY+ GG L F +AID T+SN SLH N +N+Y + I+AV LQ YD D+ FPA+GFGA++ + K+ ++PLT + +NP C GV+ +I AY L +KLS P APVI +V AK Q Y +L I+TDG V D T++A+++AS LP+SI++VGVG F D+ LD D +L E A RD VQFVP F R + ++V+ E+P Q+ Y ++ +L+P
Sbjct: 1 QDWFGKSDPFLELYKQTSIGKWKLVYRTEVHKNTLNPRWKNIVLNLQSLCDGNIAKPIKVVCADWNRNGRSNP----------IGECIVTVMQLNQAKLNNTVMFDLV-LPGNVKNSNYKNSGQLVVVLCTICRQYTFLDYIRGGCKLQFSMAIDFTASNKPPSQLDSLHHTGFNDANQYLMVIRAVGGTLQYYDADKQFPAYGFGAQLPSEEKVSQDFPLTLNANNPNCDGVQALIKAYKSCLTKVKLSEPANLAPVINRVATAAKRIKFQSKLAHEYHILFIITDGEVKDMPATREAIVQASKLPLSIVLVGVGSNDFRDLVELDSDDAILTAPSGENAFRDIVQFVPYLDFARDPVE----------KFLEQVMEEIPHQVEQYFHQMDLQP 374
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 192.971 bits (489), Expect = 4.472e-57 Identity = 112/243 (46.09%), Postives = 151/243 (62.14%), Query Frame = 1
Query: 964 VAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQV---INLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKV-GNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
V I ++SNGD DPSSLH I +NEY A+ AV +++Q+YD D+ FPA GFGA++ P++++ HE+ L + NPFC GVEG++ AY L ++L GPT F+P+I V A Q + YFVLLI+TDG + D ET+ AV++AS LP+S+I+VGVG F M+ LD D G+LK E A RD VQFVP R F K ALAK VLAE+P Q++ Y + +L P
Sbjct: 1 VGIHFSASNGDPRDPSSLHHISPTGTNEYLAAVWAVGQVIQDYDADKQFPALGFGAQLPPEWEVSHEFALNFNPLNPFCTGVEGIVQAYMACLPQVRLYGPTNFSPIINHVARFAAAAAQQPAATQYFVLLIVTDGVISDMDETRLAVVQASRLPMSLIIVGVGSADFSAMEFLDGDGGVLKAPSGEPAARDIVQFVPFRDFR----------NAPKEALAKAVLAEVPGQVVTYFKQCSLAP 233
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896]) HSP 1 Score: 108.997 bits (271), Expect = 7.216e-27 Identity = 72/254 (28.35%), Postives = 122/254 (48.03%), Query Frame = 1
Query: 70 QMIKPKVIVGIGCLNLPDTFLSYYAE------FSVATGGYIHDKDVMKTEN-QTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK----IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFL 798
Q KV + + C NL D ++ ++ G ++ ++ +TE+ + D NP+F + +DY FEE Q ++ I+ L SK + +G T+G+V+ S + + L + I + E+ ++++ +G LDKKD FGKSDPY+ +KK + G V +R+E++ NTLNP WR ++V+ LC +L + V C+D+D G + IGEF + L
Sbjct: 2 QQCVTKVEMSVSCTNLLDKDITSKSDPLCVLYMECGPGNWM---ELGRTESMKNDLNPVFAHKFQIDYHFEEVQKLRFAIYDLDSPSKRLQDHDFLGDLTLTLGQVVSSK-------KLSRALVLKDGRPAGKGIIQVLAEEMKDNRHLQLLFEGIKLDKKDFFGKSDPYLEFFKKGDDGSWVLVHRTEVVLNTLNPSWRPFTLAVQSLCGGDLDRSVRVTCYDYDSDGG---------HDFIGEFQTSVTQML 236
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO44352 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW53]) HSP 1 Score: 335.495 bits (859), Expect = 4.412e-107 Identity = 205/497 (41.25%), Postives = 298/497 (59.96%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK----IGCAESTIGRVI-HSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLY-PYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQ---YCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F + + YFFEE Q ++ +++ + K S + IG E T+G ++ +GG+L +K L +C E S CK+ ++ +G LDKKD FGKSDP+++ Y+ NE +R+E++KNTLNP W+ V LCN ++ I ++C+DWD D D +IG FS +E P + FEL N +K+ KKK Y NSG + + +++ + +F+D++ GGT ++FIVAID T+SNG+ + +SLHF++ N+Y A+ +V I Q+YD+D+LFPAFGFGAR+ P++++ HE+ L G+ NPFC VEGVI++Y +Q ++L GPT F+P+IR+ + LAK+ G YFVLLILTDG + D +TK A+++A+ LP+SII+VGVGG F M+ LD D L A RD VQFVP R +L D S LAK+VL ELP+QL DYM K N+KP
Sbjct: 62 NPDFVKKFTIHYFFEEIQKLRFQVYDIDKKSSRLQDHDFIGEIECTLGSIVGENGGQL------EKAL----------LC----EEVSQCKDVATLQFRGHKLDKKDFFGKSDPFLVFYRCNEDNSFTAVHRTEVVKNTLNPTWKPFSVPARALCNGDIDRSIRIECYDWD--------RDGSHD-LIGIFSTTLRELTSNPNL---TFELKNPKKQAKKKSYKNSGTIILLQSKLEQQPTFLDFIKGGTQISFIVAIDFTASNGNPQNSNSLHFLNPYEPNQYVKALTSVGAICQDYDSDKLFPAFGFGARLPPNWEVSHEFALNGNPQNPFCERVEGVISSYFHSIQRVQLYGPTNFSPIIRRTVALAKESERQKPGEEYFVLLILTDGIISDMEQTKAAIVDAASLPVSIIIVGVGGADFEAMEELDGDEVRLSSRGRLAERDIVQFVPFRDYL----DKCYGDITSGARLAKDVLEELPDQLTDYMKKRNIKP 522
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO39500 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9X6]) HSP 1 Score: 307.375 bits (786), Expect = 3.265e-96 Identity = 183/494 (37.04%), Postives = 281/494 (56.88%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK----IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYC-DGS--HYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKF-LRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNL 1674
NP F +++DY+FE Q +K +F + +K +G E T+G+++ + + K L + + Y E E +++ + NLD KD GKSDP++ + K G + +R+E+IKN LNP W+ + ++ LC+ + + I + C D+DG D D +IG + ++ L +LIN +KK KKK Y NSG++ + +V N+F+DY+ GG +NF V +D T+SNG+ P SLH+I+ NEY A+ +V E+ Q+YD+D+LFPAFGFGA++ P+F++ HE+ L + SNP+C G+ GV+ AY ++ ++L GPT +P+I V + A++ DG+ YFVLL++TDG + D TK A++ AS LP+S+I+VGVG F DM LD D G L+ G+E+A RD VQFVP R F +P A LAK VLAE+P+Q +Y N +
Sbjct: 55 NPDFSKAISVDYYFELVQKLKFSVFDVDNATKQLDDDDFLGSIECTLGQIVS-------KKSFTKHLEIKGRQVGT--ITIYAEEMKGANEIVKLTFRATNLDNKDFMGKSDPFLELLKLKPDGGTLLVHRTEVIKNNLNPTWKVFSLPIQSLCSADYDATIRIDCHDYDG--------DGSHD-LIGIANTSLRQLLELRQSGSGLDLINPKKKAKKKKYVNSGVLYISGCEVIHHNTFLDYVMGGCQINFTVGVDFTASNGNPSTPQSLHYINPYEPNEYVNALVSVGEVCQDYDSDKLFPAFGFGAKIPPNFQVSHEFALNFNPSNPYCEGIPGVVAAYQACIRQVQLYGPTNASPIINHVASFAQRAAQDGTAGAYFVLLLITDGVLSDMEATKLAIVRASRLPMSLIIVGVGSADFTDMNELDADEGTLRAGHERAERDIVQFVPFRDFKTQPPA-----------MLAKHVLAEVPKQAQEYFNSRGI 519
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO45927 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRD6]) HSP 1 Score: 297.36 bits (760), Expect = 1.633e-92 Identity = 198/548 (36.13%), Postives = 298/548 (54.38%), Query Frame = 1
Query: 85 KVIVGIGCLNLPDTFLSYYAEFSVATGGYIHD--KDVMKTEN-QTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISK----IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEF--LYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGS----HYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKPIGE 1689
+V + I C NL D + ++ V H+ ++V +TE + NP F + +DYFFEE Q +K ++ + S K +G + T+G+++ S +Y N++I + D FGKSDPY+ + E G V +R+E++ N LNP W+ I +S ++LCN + + V C+DWD D+ ++IG F+ +E E ++ IN +K+KKKK Y NSG++ + + QV + SF+D++ GG +NF V ID T SNG+ P+SLH+I+ + NEY A+ AV EI+Q+YD+D+LFPAFGFGA+V P+ + H++ L + +NPFC G++G+I AY + ++ + L GPT AP+I V A+ +Y++LLILTDG + D +TK+A+++AS LP+SII+VGVG F M+ LD D GLL+ A RD VQFVP RKF S ALAKEVLAE+P Q+ Y N+ P G+
Sbjct: 26 RVQLNISCKNLIDKDVMSKSDPLVVVMMLRHNNWEEVGRTERLENTLNPNFSTTIVVDYFFEELQKLKFMVYDIDSASGSLKNADFLGEMQCTLGQLVSSA-------------TY--------------------THNLKIPSGKPAGNMTDFFGKSDPYLEFSRAKEDGSFVVVHRTEVVSNNLNPKWKPIHISSQQLCNGDYDRVLKVNCYDWD---------DDGSHDLIGTFTTTLRELSTCQQGGAELQWPCINEKKRKKKKNYKNSGVIFLSSCQVVRVASFLDFIQGGCQINFTVGIDFTGSNGNPASPTSLHYINPYAPNEYCQALTAVGEIIQDYDSDKLFPAFGFGAKVPPNNMVSHQFALNFNHTNPFCAGLQGLIEAYQQCVRQVTLYGPTNIAPIISNVAMYAQAAAQQPYASLNYYILLILTDGVISDMDQTKRAIVQASGLPMSIIIVGVGSADFEMMEELDADDGLLRSEGSTAQRDIVQFVPFRKF----------KNLSSAALAKEVLAEVPGQVTGYYKMRNISPGGQ 521
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO49902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF64]) HSP 1 Score: 174.866 bits (442), Expect = 8.892e-48 Identity = 119/384 (30.99%), Postives = 187/384 (48.70%), Query Frame = 1
Query: 322 IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYC--DGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDM 1467
IGC E I ++ + + V D+ ++ I +FY E N+ ++ G NL+K+ L K D + + + G YRSEI+ TL+P W + ++KLCN+ + E + C+ + + + +I P + I + +L+ +K +K + +G + + V K S +DY+ GG D+ AID T SNGD SSLH + NEY A++A+ +L YD D+ P F FGA+ C + L GD S P +E +I+ Y L IKL GPTY PVI+++ + A + D HY V +++ DG +D +TK+ +I+ S LP+SI+VVGVG F M
Sbjct: 88 IGCTEIDIDSLLSAESPYVRTLRVPGDI-----QTRGFIKLFY-EEVHTSLTNVRFQISGVNLEKRSLLSKWDVFFELERLLPGGFYHPVYRSEIVARTLDPRWSPFDIYLQKLCNEEVTREAVISCWHYSSSGAN---------TLIASARCPVGHLINRSI--KVLQLVKPQKTQKARRAGTAGSLRIDHCHVDKHFSLVDYIRGGCDVTIACAIDFTLSNGDPSCRSSLHTLSCLYQNEYIGALRALGPVLMHYDEDKQIPTFAFGAKSKHGIPYC--FALNGDESEPEISSIETLIDTYTRSLTTIKLGGPTYLVPVIKRLADYATRELSQDSQHYLVAMVIMDGVANDLDDTKEQIIQVSGLPLSIVVVGVGPADFTAM 452
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO26801 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TB16]) HSP 1 Score: 134.035 bits (336), Expect = 6.882e-35 Identity = 78/195 (40.00%), Postives = 117/195 (60.00%), Query Frame = 1
Query: 517 KDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEF--LYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYD 1095
KD FGKSDPY+ + E G V +R+E++ N LNP W+ I +S ++LCN + + V C+DWD D+ ++IG F+ +E E ++ IN +K+KKKK Y NSG++ + + QV + SF+D++ GG +NF V ID T SNG+ P+SLH+I+ + NEY A+ AV EI+Q+YD
Sbjct: 106 KDFFGKSDPYLEFSRAKEDGSFVVVHRTEVVSNNLNPKWKPIHISSQQLCNGDYDRVLKVNCYDWD---------DDGSHDLIGTFTTTLRELSTCQQGGAELQWPCINEKKRKKKKNYKNSGVIFLSSCQVVRVASFLDFIQGGCQINFTVGIDFTGSNGNPASPTSLHYINPYAPNEYCQALTAVGEIIQDYD 291 HSP 2 Score: 65.4698 bits (158), Expect = 1.182e-11 Identity = 27/73 (36.99%), Postives = 43/73 (58.90%), Query Frame = 1
Query: 451 VREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCN 669
E + + +++ + LD KD FGKSDPY+ + E G V +R+E++ N LNP W+ I +S ++LCN
Sbjct: 26 TEEVAGTNDEVQMVFRAQKLDNKDFFGKSDPYLEFSRAKEDGSFVVVHRTEVVSNNLNPKWKPIHISSQQLCN 98
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne8 (copine-8 [Source:NCBI gene;Acc:101173626]) HSP 1 Score: 356.295 bits (913), Expect = 3.640e-114 Identity = 203/492 (41.26%), Postives = 304/492 (61.79%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXG-YSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEE+Q ++ +++ L K +SK +G A T+G ++ S G ++K L G I E S+C+E++ ++ G LDKKD FGKSDP+++ Y+ NE G +++E++KNTL+P W++ + V LCN + I V+ +DWD G + IGEFS +E Q +E++N +KK KKK Y NSG VT+ + V + SF+DY+ GGT +NF VAID T+SNG+ P+SLH++ N+Y++A++AV EI+Q+YD+D+LFPA GFGA++ PD ++ HE+PL G+ NP+C+G++GV+ AY++ L++++L GPT+F+PVI V A DGS YF+LLI++DG + D +TK++++ A+ LP+SII+VGVG +F +M LD D + A RD VQFVP R ++ D N S LAKEVLAE+P+Q L YM +K
Sbjct: 69 NPDFVRKFILDYFFEERQNLRFDLYDLDCKSDNLSKHDFLGQAFCTLGEIVGSLGS-----RLEKPL-IGIPGKKCGTIIVRAEELSNCRESVMLQFCGNKLDKKDFFGKSDPFLVFYRSNEDGSYTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRSIKVEVYDWDRDGGH---------DFIGEFSTSYREMSRSQSQFHIYEVLNPKKKGKKKKKYLNSGTVTLLSCLVDTELSFLDYIRGGTQINFTVAIDFTASNGNPSQPTSLHYMSPYQLNDYAMALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPQNPYCNGIDGVLEAYYQSLKSVRLYGPTHFSPVINHVARYASAVTDGSQYFILLIISDGVITDMAQTKESIVNAASLPMSIIIVGVGPAEFDEMIELDGDEERISSQGRYAERDIVQFVPFRDYI----DRRGNHILSMARLAKEVLAEIPDQFLSYMRTRGIK 541
BLAST of Copine-3 vs. Ensembl Medaka
Match: CPNE8 (copine 8 [Source:NCBI gene;Acc:101158741]) HSP 1 Score: 355.525 bits (911), Expect = 6.835e-114 Identity = 204/491 (41.55%), Postives = 304/491 (61.91%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEE+Q ++++++ + +K + +SK +G A T+G ++ S G ++K L G I E ++C+E++ ++ G LDKKD FGKSDP++I Y+ NE G +++E++KNTLNP W++ + V LCN + I V+ +DWD D ++F IGEFS +E Q +E++N +KK KKK Y NSG VT+ + V + +F+DY+ GGT +NF VAID T+SNG+ P+SLH++ N Y++A++AV EI+Q+YD+D++FPA GFGA++ PD ++ HE+ L G+ NP+C G++GV+ AY++ L++++L GPT FAPVI V A DGS YFVLLI+TDG + D TK+A++ AS LP+SI++VGVG +F M LD D + A RD VQFVP R ++ D + N S LAK+VLAE+P+Q L YM +K
Sbjct: 74 NPDFVRKFILDYFFEERQNLRLDLYDVDSKSANLSKHDFLGQAYCTLGEIVGSLGS-----RLEKPLG-GIPGKKCGTIIVKAEELNNCRESVMMQFCGNKLDKKDFFGKSDPFLIFYRSNEDGTFTICHKTEVVKNTLNPVWQAFKIPVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFSTSYRELSRGQSQFNVYEVVNPKKKGKKKKYLNSGTVTLLSFLVDIEVTFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMSPYQLNTYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFALNGNPQNPYCDGIDGVMEAYYQTLKSVQLYGPTNFAPVINHVARYAASVKDGSQYFVLLIITDGVITDMALTKEAIVNASGLPMSILIVGVGPAEFDAMVELDGDEVRISSRGRLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFLSYMRTRGIK 545
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5b (copine-8 [Source:NCBI gene;Acc:101170754]) HSP 1 Score: 353.984 bits (907), Expect = 6.837e-114 Identity = 200/491 (40.73%), Postives = 301/491 (61.30%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + +K +SK +G T+G ++ S ++K L G I E S+C+++ ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + I V+ +DWD D ++F IG+F+ +E Q +E+IN++KK KKK Y NSG VT+ + V + +F+DY+ GGT +NF VAID T+SNG+ +SLH+++ N Y++A++AV EI+Q+YD+D++FPA GFGA++ PD ++ HE+PL G+ NP+C+G+EG++ AYHE L+ ++L GPT FAPV+ V A DGS YFVLLI+TDG + D +TK+A++ A+ LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LAK+VLAE+P+Q + YM +K
Sbjct: 28 NPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQVFCTLGEIVGSPAS-----RLEKPLG-GIPGKKCGTIILSAEELSNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGDFTTSYRELARGQSQFNVYEVINTKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQLNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNLENPYCNGIEGILEAYHESLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRVSSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSRGVK 499
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5b (copine-8 [Source:NCBI gene;Acc:101170754]) HSP 1 Score: 354.755 bits (909), Expect = 7.208e-113 Identity = 200/491 (40.73%), Postives = 301/491 (61.30%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGL-AKDSKISK---IGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLK 1677
NP F + LDYFFEEKQ ++ +++ + +K +SK +G T+G ++ S ++K L G I E S+C+++ ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + I V+ +DWD D ++F IG+F+ +E Q +E+IN++KK KKK Y NSG VT+ + V + +F+DY+ GGT +NF VAID T+SNG+ +SLH+++ N Y++A++AV EI+Q+YD+D++FPA GFGA++ PD ++ HE+PL G+ NP+C+G+EG++ AYHE L+ ++L GPT FAPV+ V A DGS YFVLLI+TDG + D +TK+A++ A+ LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LAK+VLAE+P+Q + YM +K
Sbjct: 136 NPDFVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQVFCTLGEIVGSPAS-----RLEKPLG-GIPGKKCGTIILSAEELSNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGDFTTSYRELARGQSQFNVYEVINTKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQLNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNLENPYCNGIEGILEAYHESLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRVSSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSRGVK 607
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5a (copine-5 [Source:NCBI gene;Acc:101166794]) HSP 1 Score: 351.673 bits (901), Expect = 2.729e-112 Identity = 199/490 (40.61%), Postives = 304/490 (62.04%), Query Frame = 1
Query: 217 NPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKIGCAESTIGRVIHSGGELF--LQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKP 1680
NP F + LDYFFEEKQ ++ +++ + DSK +G +G+V + GE+ ++K L ++ I I E +C++ ++ LDKKD FGKSDP+++ Y+ NE G +++E++KNTLNP W+ + V LCN + I V+ +DWD D ++F IGEFS KE + +E++N++KK KKK Y NSG V++ + V +++F+DY+ GGT ++F VAID T+SNG+ +SLH+++ N Y++A++AV EI+Q+YD+D++FPA GFGA++ PD ++ HE+PL G+ NP+C+G+EG++ AYH+ L+ ++L GPT FAPV+ V A DGS YF+LLI+TDG + D +TK+A++ A+ LP+SII+VGVG +F M LD D + + A RD VQFVP R ++ D + N S LAK+VLAE+P+QL+ YM +KP
Sbjct: 78 NPDFVRKYILDYFFEEKQNLRFDVYDI--DSKSPDLG-KHDFLGQVYCTLGEIVGSPASRLEKPLGGIPGKTCGTI-ILSAEELGNCRDYATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPMWQPFSIPVRALCNGDYDRTIKVEVYDWD------RDGSHDF---IGEFSTSYKELCRGQSESNVYEVVNAKKKLKKKRYINSGTVSLLSFSVESEHTFLDYIKGGTQIHFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNVENPYCNGMEGILEAYHQSLKLVQLYGPTNFAPVVNHVARYAAAVEDGSQYFILLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQLISYMKSRAIKP 550
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000029196.1 (SMESG000029196.1) HSP 1 Score: 1219.14 bits (3153), Expect = 0.000e+0 Identity = 603/605 (99.67%), Postives = 605/605 (100.00%), Query Frame = 1
Query: 73 MIKPKVIVGIGCLNLPDTFLSYYAEFSVATGGYIHDKDVMKTENQTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKIGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKPIGENKSLLSATLDNSKLNAKEFVQQKLRRCATAYGMTKSNRQGSTDGLNGRGFRGTRKCSVDSQFLEEM 1887
MIKPKVIVGIGCLNLPDTFLSYYAEFSVATGGYIHDKDVMKTENQTDQNPIFKCQLNLDYFFEEKQCIKVEIFGL+KDSKISKIGCAESTIGRVIHSGGELFLQIN+DKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRKKKKKKGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIVVGVGGGKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKPIGENKSLLSATLDNSKLNAKEFVQQKLRRCATAYGMTKSNRQGSTDGLNGRGFRGTRKCSVDSQFLEEM
Sbjct: 1 MIKPKVIVGIGCLNLPDTFLSYYAEFSVATGGYIHDKDVMKTENQTDQNPIFKCQLNLDYFFEEKQCIKVEIFGLSKDSKISKIGCAESTIGRVIHSGGELFLQINIDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRKKKKKKGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIVVGVGGGKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKPIGENKSLLSATLDNSKLNAKEFVQQKLRRCATAYGMTKSNRQGSTDGLNGRGFRGTRKCSVDSQFLEEM 605
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000007275.1 (SMESG000007275.1) HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0 Identity = 358/605 (59.17%), Postives = 458/605 (75.70%), Query Frame = 1
Query: 79 KPKVIVGIGCLNLP-DTFLSYYAEFSVATGGYIHDKDVMKTENQTDQNPI-FKCQLNLDYFFEEKQCIKVEIFGLAKDSKISKIGCAESTIGRVIHSGGELFLQINVDKDLSYGNNESHSPICIFY-VREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFLYPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNKHNLKPIGENKSLLSATLDNSKLNAKEFVQ-QKLRRCATAYGMTKSNRQGSTDGLNGRGFRGTRKCSVDSQFLE 1881
K KV++ + C NLP ++F YYA VATGGY HDKD + TE D I F +L L+Y FEEKQ I++E+ G+ + + + E ++GR+IHSGGEL + + I I Y V ED+ K+N+EIKMQG+ LDKKD+FGKSDPYVI+Y++N++GKL++TYRSE++KNTLNPDW++++ S+E+LC +L E+ KCFDWDGA GDPEDMD EFDE+IGEF+ + L +++KFEL+NSRKKKKKK Y +SG++T+RT Q D SF+DYMFGGTDLNFIVAIDLTSSNGD+ DP+SLH++D N++NEYS+AIQAVLEILQEYDNDE+FPAFGFGARV PDFKI HEYPL GD+SNPFC GVEGV+ AY E L +KLSGPT+FAPVIRQV NL+K++ DGSHYF+LLILTDG+VDDW+ETK+AVIEAS+LP+SIIV+GVGG KF DM+ LDQDF LL+VGN+QACRDNVQFVPMR+FLR AADGSD+++W+KV+LAKEVLAELP Q+L YM++H +G +S L ++F Q +LRRCAT+ +S + S + + R+CSVD+ E
Sbjct: 4 KSKVLISLSCRNLPTESFEMYYATLRVATGGYFHDKDTISTEKVKDSKDIDFIQKLQLEYIFEEKQIIRIELHGIYF-GESACVATLECSVGRIIHSGGEL------SRFTEWCWKSITCEIEIIYKVTEDAASKDNLEIKMQGYGLDKKDIFGKSDPYVIIYRRNDKGKLIRTYRSEVVKNTLNPDWKAVVASLERLCGNDLDCELIFKCFDWDGANGDPEDMDTEFDELIGEFTTTTRYLLSANGEQKKFELVNSRKKKKKKNYQHSGLITIRTIQTITDLSFLDYMFGGTDLNFIVAIDLTSSNGDVEDPTSLHYMDVNNTNEYSVAIQAVLEILQEYDNDEMFPAFGFGARVPPDFKISHEYPLNGDYSNPFCKGVEGVMKAYREALLQVKLSGPTHFAPVIRQVSNLSKEHRDGSHYFILLILTDGSVDDWVETKRAVIEASYLPVSIIVIGVGGRKFSDMEILDQDFKLLRVGNDQACRDNVQFVPMRRFLRAAADGSDSIRWNKVSLAKEVLAELPVQVLHYMSRHK-GALGPRRSEHYRYCSMKDL-LRQFSQDTRLRRCATSSYDDQSPKHMSQRRASSCLLKTGRQCSVDTSLQE 599
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000064685.1 (SMESG000064685.1) HSP 1 Score: 580.096 bits (1494), Expect = 0.000e+0 Identity = 319/621 (51.37%), Postives = 431/621 (69.40%), Query Frame = 1
Query: 79 KPKVIVGIGCLNLPDTFLS-YYAEFSVATGGYIHDKDVMKTENQTDQNPIFKCQLNLDYFFEEKQCIKVEIF--GLAKDSKISKIGCAESTIGRVIHSGGELF--LQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFL-YPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNK--------HNLKPIGENKSLLSATLDNSKLNAKEFVQQKLRRCATAYGMTKSNRQGSTDG-----LNGRGFRGTRKCSVDSQFLEE 1884
KPKV++ + NL T Y+A SV TGGYIH +D +KTE ++ + F +L ++Y FEEKQ I +EIF + +D + +G + +IGRVIHSGG + L+I + + G SP YV ED KENIE+K++G L K ++FGK+DPY+++++ N R + V+ YR+E++KNT NPDW I+VS E+LCN +L S + ++ + DG + E++D D+++GE + A+E + ++E++FELIN +KKKKKK Y NSGI++VR + + + +F+D+MF G +LNFIVAIDLT SNGD PSSLHF+D + +NEYS+AIQAVLEILQEYDNDELFPAFGFGARV PD+KICHEYPL GDF NP+C G EGVI+AY + L+ +KL+GPT F+PVIR + LAK G HYFVLLILTDG+VDDW+ETKKAV+E S+LP+SIIVVGVGGGKF DM+TLDQDFGLL V NE+ACRDNVQFV MR++LR AADGSDN++WSKVALAK+VLAELP Q+ +YM++ NL P + ++ S+ L + + + L+R T + +S R +G R + TR+ SVDS +
Sbjct: 6 KPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGD-NLLGEVDCSIGRVIHSGGVILKPLEITNEFKTTLG---PLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENL-PTQRSTAVFSSCLRQN--CSSDPNSLSLQRTPT---LNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSK 616
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000064685.1 (SMESG000064685.1) HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0 Identity = 319/621 (51.37%), Postives = 431/621 (69.40%), Query Frame = 1
Query: 79 KPKVIVGIGCLNLPDTFLS-YYAEFSVATGGYIHDKDVMKTENQTDQNPIFKCQLNLDYFFEEKQCIKVEIF--GLAKDSKISKIGCAESTIGRVIHSGGELF--LQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFL-YPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNK--------HNLKPIGENKSLLSATLDNSKLNAKEFVQQKLRRCATAYGMTKSNRQGSTDG-----LNGRGFRGTRKCSVDSQFLEE 1884
KPKV++ + NL T Y+A SV TGGYIH +D +KTE ++ + F +L ++Y FEEKQ I +EIF + +D + +G + +IGRVIHSGG + L+I + + G SP YV ED KENIE+K++G L K ++FGK+DPY+++++ N R + V+ YR+E++KNT NPDW I+VS E+LCN +L S + ++ + DG + E++D D+++GE + A+E + ++E++FELIN +KKKKKK Y NSGI++VR + + + +F+D+MF G +LNFIVAIDLT SNGD PSSLHF+D + +NEYS+AIQAVLEILQEYDNDELFPAFGFGARV PD+KICHEYPL GDF NP+C G EGVI+AY + L+ +KL+GPT F+PVIR + LAK G HYFVLLILTDG+VDDW+ETKKAV+E S+LP+SIIVVGVGGGKF DM+TLDQDFGLL V NE+ACRDNVQFV MR++LR AADGSDN++WSKVALAK+VLAELP Q+ +YM++ NL P + ++ S+ L + + + L+R T + +S R +G R + TR+ SVDS +
Sbjct: 6 KPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGD-NLLGEVDCSIGRVIHSGGVILKPLEITNEFKTTLG---PLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENL-PTQRSTAVFSSCLRQN--CSSDPNSLSLQRTPT---LNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSK 616
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000064685.1 (SMESG000064685.1) HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0 Identity = 319/621 (51.37%), Postives = 431/621 (69.40%), Query Frame = 1
Query: 79 KPKVIVGIGCLNLPDTFLS-YYAEFSVATGGYIHDKDVMKTENQTDQNPIFKCQLNLDYFFEEKQCIKVEIF--GLAKDSKISKIGCAESTIGRVIHSGGELF--LQINVDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFL-YPYIQERKFELINSRXXXXXXGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIXXXXXXXKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNK--------HNLKPIGENKSLLSATLDNSKLNAKEFVQQKLRRCATAYGMTKSNRQGSTDG-----LNGRGFRGTRKCSVDSQFLEE 1884
KPKV++ + NL T Y+A SV TGGYIH +D +KTE ++ + F +L ++Y FEEKQ I +EIF + +D + +G + +IGRVIHSGG + L+I + + G SP YV ED KENIE+K++G L K ++FGK+DPY+++++ N R + V+ YR+E++KNT NPDW I+VS E+LCN +L S + ++ + DG + E++D D+++GE + A+E + ++E++FELIN +KKKKKK Y NSGI++VR + + + +F+D+MF G +LNFIVAIDLT SNGD PSSLHF+D + +NEYS+AIQAVLEILQEYDNDELFPAFGFGARV PD+KICHEYPL GDF NP+C G EGVI+AY + L+ +KL+GPT F+PVIR + LAK G HYFVLLILTDG+VDDW+ETKKAV+E S+LP+SIIVVGVGGGKF DM+TLDQDFGLL V NE+ACRDNVQFV MR++LR AADGSDN++WSKVALAK+VLAELP Q+ +YM++ NL P + ++ S+ L + + + L+R T + +S R +G R + TR+ SVDS +
Sbjct: 6 KPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGD-NLLGEVDCSIGRVIHSGGVILKPLEITNEFKTTLG---PLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENL-PTQRSTAVFSSCLRQN--CSSDPNSLSLQRTPT---LNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSK 616 The following BLAST results are available for this feature:
BLAST of Copine-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Copine-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Copine-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Copine-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Copine-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Copine-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Copine-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Copine-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Copine-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024549 ID=SMED30024549|Name=Copine-3|organism=Schmidtea mediterranea sexual|type=transcript|length=2140bpback to top protein sequence of SMED30024549-orf-1 >SMED30024549-orf-1 ID=SMED30024549-orf-1|Name=SMED30024549-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=622bp MIKPKVIVGIGCLNLPDTFLSYYAEFSVATGGYIHDKDVMKTENQTDQNPback to top Aliases
The feature 'Copine-3' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
