Cyclic nucleotide gated channel 1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppSub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024524 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Match: HCN1 (hyperpolarization activated cyclic nucleotide gated potassium channel 1 [Source:HGNC Symbol;Acc:HGNC:4845]) HSP 1 Score: 435.261 bits (1118), Expect = 2.905e-144 Identity = 232/440 (52.73%), Postives = 313/440 (71.14%), Query Frame = 3 Query: 516 EYIGGGAPGYRHPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 E GG PR +++ Q S+ QPG NK ++++FG+Q A+ KE+ R K G WIIHP S FRFYWDL+ML+++V NL+++PV I+FF + + W++FN SDT+FLLD+ +NFRTG + N+ + EIIL+PK I +Y +SWF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + IFNL+ MMLLL HW+ CLQFL+P++++FP DCW+ + +W QY+++LFKAMSHML IGYG P S S+ W+T++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQKI DYYEHRYQG +F+E +IL EL++ LRE+++N+NCR LVA++P F NAD LS + F RE ++ KK Sbjct: 75 EEPAGGFEDAEGPRRQYG-FMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTV-NEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMD-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKK 511 HSP 2 Score: 132.494 bits (332), Expect = 1.112e-31 Identity = 62/105 (59.05%), Postives = 78/105 (74.29%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EG VG +MYFIQ G+ +ITK + L+DGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 483 FVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSK-EMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 586
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Match: HCN4 (hyperpolarization activated cyclic nucleotide gated potassium channel 4 [Source:HGNC Symbol;Acc:HGNC:16882]) HSP 1 Score: 447.973 bits (1151), Expect = 1.546e-142 Identity = 234/427 (54.80%), Postives = 311/427 (72.83%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 RL + +++ Q ++ QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWDL ML+++V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI++ D EIIL+P++I Y +SWF++DF+SSIPVDYIFLI+ T S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ N+ +W QY+++LFKAMSHML IGYGR P S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQ+I DYYEHRYQG MF+E IL ELSE LRE++IN+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 207 RLGQAGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVED-NTEIILDPQRIKMKYLKSWFMVDFISSIPVDYIFLIVE-TRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSINNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKK 631 HSP 2 Score: 141.354 bits (355), Expect = 4.501e-34 Identity = 64/105 (60.95%), Postives = 81/105 (77.14%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G T L+DGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 603 FVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 706
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Match: HCN1 (hyperpolarization activated cyclic nucleotide gated potassium channel 1 [Source:HGNC Symbol;Acc:HGNC:4845]) HSP 1 Score: 438.728 bits (1127), Expect = 4.079e-142 Identity = 232/440 (52.73%), Postives = 313/440 (71.14%), Query Frame = 3 Query: 516 EYIGGGAPGYRHPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 E GG PR +++ Q S+ QPG NK ++++FG+Q A+ KE+ R K G WIIHP S FRFYWDL+ML+++V NL+++PV I+FF + + W++FN SDT+FLLD+ +NFRTG + N+ + EIIL+PK I +Y +SWF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + IFNL+ MMLLL HW+ CLQFL+P++++FP DCW+ + +W QY+++LFKAMSHML IGYG P S S+ W+T++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQKI DYYEHRYQG +F+E +IL EL++ LRE+++N+NCR LVA++P F NAD LS + F RE ++ KK Sbjct: 75 EEPAGGFEDAEGPRRQYG-FMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTV-NEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMD-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKK 511 HSP 2 Score: 132.88 bits (333), Expect = 1.758e-31 Identity = 62/105 (59.05%), Postives = 78/105 (74.29%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EG VG +MYFIQ G+ +ITK + L+DGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 483 FVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSK-EMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 586
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Match: HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 [Source:HGNC Symbol;Acc:HGNC:4846]) HSP 1 Score: 437.958 bits (1125), Expect = 7.377e-142 Identity = 234/446 (52.47%), Postives = 315/446 (70.63%), Query Frame = 3 Query: 498 SEQSLSEYIGGGAPGYRHPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 +E++ SE G PR S + +++ Q +L QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWD ML+ +V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI++ D EIIL+P++I K Y R+WF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP +CW+ + +W + Y+++LFKAMSHML IGYGR P S ++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQKI DYYEHRYQG MF+E IL EL+ LRE+++N+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 141 AEEAGSEEAGPAG----EPRGSQASFMQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIED-NTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGID-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKK 580 HSP 2 Score: 137.502 bits (345), Expect = 6.286e-33 Identity = 64/105 (60.95%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G LSDGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 552 FVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 655
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Match: HCN3 (hyperpolarization activated cyclic nucleotide gated potassium channel 3 [Source:HGNC Symbol;Acc:HGNC:19183]) HSP 1 Score: 419.468 bits (1077), Expect = 3.927e-136 Identity = 222/420 (52.86%), Postives = 298/420 (70.95%), Query Frame = 3 Query: 579 KEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHF-SQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 + + +L QP NK ++++FG+ A+ E+ R K G WIIHP S FRFYWDL+ML+++V NLIVLPV I+FF ++ S W+VFN +SDT FLLD+ +NFRTGI++ + A EI+L P+ I Y R+WF++D +SSIPVDYIFL++ ++ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + IFNL+ MMLLL HW+ CLQFL+PM+++FP DCW+ ++ +W QY+ +LFKAMSHML IGYG+ P + W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQ+I +YYEHRYQG MF+E IL ELSE LRE++IN+ CRGLVA +P F +AD L+ + F RE S+ +K Sbjct: 46 RRHLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGA-EILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRK 464 HSP 2 Score: 130.183 bits (326), Expect = 1.003e-30 Identity = 59/105 (56.19%), Postives = 79/105 (75.24%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ V+ KL +EVFQPGD +++EG+VG +MYFIQ G++ ++ + G T L+DGSYFGEICLL RR ASVRA TYC +YSL + F +VLE +P+MRR E+V Sbjct: 436 FVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLAR-GARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETV 539
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Match: unc-103 (Potassium voltage-gated channel unc-103 [Source:UniProtKB/Swiss-Prot;Acc:G5EFJ9]) HSP 1 Score: 118.242 bits (295), Expect = 8.993e-35 Identity = 109/435 (25.06%), Postives = 207/435 (47.59%), Query Frame = 3 Query: 534 APGYRHPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGH--WIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDL---------SKRWLVFNGVSDTIFLLDIGVNFRTGII-LNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMML---LLGHWNACLQFLIPMM----REFPNDCWIVKCNLKEANWF---------------DQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEID---ILQELSECLREKVINYNCRGLVASVPFFKNA 1727 APG PR S S ++ +N A+ + + +L E Q H I+H S F+ WD ++L++++ + P +F +L ++ + + + D +F++DI +NFRT + ND A +++ +P +IA HY + WFIID ++++P D + L+ N++ + + LL RLLRL R+ R + ++ E+ G L+L+M L+ HW AC+ + I +E+ W+ + + + A + +Y SL+ +S + SIG+G T+ SE TI+ M+ G+ YA G+ +A+IQ + Y + ++ E++ + ++P LRQ++ +Y++H + + N ID +L+ +CL+ + + R L++ F + Sbjct: 61 APGAGGPRASHSSRRTSRL------HNNVSALGVLSLGADVLPEYKLQPTRIHHCTIVH-YSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIVDIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFD-LLLVSTNSDETTTLI------------GLLKTARLLRLVRVARKLDRYSEY--------GAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEY---TWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAW--SYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGS 462 HSP 2 Score: 48.9062 bits (115), Expect = 8.993e-35 Identity = 30/83 (36.14%), Postives = 47/83 (56.63%), Query Frame = 2 Query: 1781 PGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADT--RRVASVRAVTYCNVYSLDRESFLSVLEHYP 2023 PGD ++ G + + +YFI G V+I+ D + L FGE LL D + +VRA+TYC+++ + R+ L VL+ YP Sbjct: 481 PGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 563
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Match: unc-103 (Potassium voltage-gated channel unc-103 [Source:UniProtKB/Swiss-Prot;Acc:G5EFJ9]) HSP 1 Score: 115.161 bits (287), Expect = 6.791e-34 Identity = 102/405 (25.19%), Postives = 196/405 (48.40%), Query Frame = 3 Query: 624 AMKLFGTQSALLKEKSRQKKHGH--WIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDL---------SKRWLVFNGVSDTIFLLDIGVNFRTGII-LNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMML---LLGHWNACLQFLIPMM----REFPNDCWIVKCNLKEANWF---------------DQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEID---ILQELSECLREKVINYNCRGLVASVPFFKNA 1727 A K+ + +L E Q H I+H S F+ WD ++L++++ + P +F +L ++ + + + D +F++DI +NFRT + ND A +++ +P +IA HY + WFIID ++++P D + L+ N++ + + LL RLLRL R+ R + ++ E+ G L+L+M L+ HW AC+ + I +E+ W+ + + + A + +Y SL+ +S + SIG+G T+ SE TI+ M+ G+ YA G+ +A+IQ + Y + ++ E++ + ++P LRQ++ +Y++H + + N ID +L+ +CL+ + + R L++ F + Sbjct: 119 AQKVLSLGADVLPEYKLQPTRIHHCTIVH-YSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIVDIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFD-LLLVSTNSDETTTLI------------GLLKTARLLRLVRVARKLDRYSEY--------GAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEY---TWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAW--SYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGS 496 HSP 2 Score: 48.9062 bits (115), Expect = 6.791e-34 Identity = 30/83 (36.14%), Postives = 47/83 (56.63%), Query Frame = 2 Query: 1781 PGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADT--RRVASVRAVTYCNVYSLDRESFLSVLEHYP 2023 PGD ++ G + + +YFI G V+I+ D + L FGE LL D + +VRA+TYC+++ + R+ L VL+ YP Sbjct: 515 PGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 597
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Match: unc-103 (Potassium voltage-gated channel unc-103 [Source:UniProtKB/Swiss-Prot;Acc:G5EFJ9]) HSP 1 Score: 114.39 bits (285), Expect = 1.153e-33 Identity = 102/409 (24.94%), Postives = 198/409 (48.41%), Query Frame = 3 Query: 612 DNKLAMKLFGTQSALLKEKSRQKKHGH--WIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDL---------SKRWLVFNGVSDTIFLLDIGVNFRTGII-LNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMML---LLGHWNACLQFLIPMM----REFPNDCWIVKCNLKEANWF---------------DQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEID---ILQELSECLREKVINYNCRGLVASVPFFKNA 1727 D++ K+ + +L E Q H I+H S F+ WD ++L++++ + P +F +L ++ + + + D +F++DI +NFRT + ND A +++ +P +IA HY + WFIID ++++P D + L+ N++ + + LL RLLRL R+ R + ++ E+ G L+L+M L+ HW AC+ + I +E+ W+ + + + A + +Y SL+ +S + SIG+G T+ SE TI+ M+ G+ YA G+ +A+IQ + Y + ++ E++ + ++P LRQ++ +Y++H + + N ID +L+ +CL+ + + R L++ F + Sbjct: 57 DDEEENKVLSLGADVLPEYKLQPTRIHHCTIVH-YSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIVDIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFD-LLLVSTNSDETTTLI------------GLLKTARLLRLVRVARKLDRYSEY--------GAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEY---TWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAW--SYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGS 438 HSP 2 Score: 48.9062 bits (115), Expect = 1.153e-33 Identity = 30/83 (36.14%), Postives = 47/83 (56.63%), Query Frame = 2 Query: 1781 PGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADT--RRVASVRAVTYCNVYSLDRESFLSVLEHYP 2023 PGD ++ G + + +YFI G V+I+ D + L FGE LL D + +VRA+TYC+++ + R+ L VL+ YP Sbjct: 457 PGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 539
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Match: unc-103 (Potassium voltage-gated channel unc-103 [Source:UniProtKB/Swiss-Prot;Acc:G5EFJ9]) HSP 1 Score: 114.39 bits (285), Expect = 1.254e-33 Identity = 104/419 (24.82%), Postives = 202/419 (48.21%), Query Frame = 3 Query: 582 EQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGH--WIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDL---------SKRWLVFNGVSDTIFLLDIGVNFRTGII-LNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMML---LLGHWNACLQFLIPMM----REFPNDCWIVKCNLKEANWF---------------DQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEID---ILQELSECLREKVINYNCRGLVASVPFFKNA 1727 +Q+ + Q G + K+ + +L E Q H I+H S F+ WD ++L++++ + P +F +L ++ + + + D +F++DI +NFRT + ND A +++ +P +IA HY + WFIID ++++P D + L+ N++ + + LL RLLRL R+ R + ++ E+ G L+L+M L+ HW AC+ + I +E+ W+ + + + A + +Y SL+ +S + SIG+G T+ SE TI+ M+ G+ YA G+ +A+IQ + Y + ++ E++ + ++P LRQ++ +Y++H + + N ID +L+ +CL+ + + R L++ F + Sbjct: 37 KQLMVVLQSG----SYKVLSLGADVLPEYKLQPTRIHHCTIVH-YSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIVDIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFD-LLLVSTNSDETTTLI------------GLLKTARLLRLVRVARKLDRYSEY--------GAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEY---TWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAW--SYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGS 424 HSP 2 Score: 48.9062 bits (115), Expect = 1.254e-33 Identity = 30/83 (36.14%), Postives = 47/83 (56.63%), Query Frame = 2 Query: 1781 PGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADT--RRVASVRAVTYCNVYSLDRESFLSVLEHYP 2023 PGD ++ G + + +YFI G V+I+ D + L FGE LL D + +VRA+TYC+++ + R+ L VL+ YP Sbjct: 443 PGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 525
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Match: unc-103 (Potassium voltage-gated channel unc-103 [Source:UniProtKB/Swiss-Prot;Acc:G5EFJ9]) HSP 1 Score: 114.39 bits (285), Expect = 1.284e-33 Identity = 104/419 (24.82%), Postives = 202/419 (48.21%), Query Frame = 3 Query: 582 EQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGH--WIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDL---------SKRWLVFNGVSDTIFLLDIGVNFRTGII-LNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMML---LLGHWNACLQFLIPMM----REFPNDCWIVKCNLKEANWF---------------DQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEID---ILQELSECLREKVINYNCRGLVASVPFFKNA 1727 +Q+ + Q G + K+ + +L E Q H I+H S F+ WD ++L++++ + P +F +L ++ + + + D +F++DI +NFRT + ND A +++ +P +IA HY + WFIID ++++P D + L+ N++ + + LL RLLRL R+ R + ++ E+ G L+L+M L+ HW AC+ + I +E+ W+ + + + A + +Y SL+ +S + SIG+G T+ SE TI+ M+ G+ YA G+ +A+IQ + Y + ++ E++ + ++P LRQ++ +Y++H + + N ID +L+ +CL+ + + R L++ F + Sbjct: 37 KQLMVVLQSG----SYKVLSLGADVLPEYKLQPTRIHHCTIVH-YSPFKAVWDWIILLLVIYTAVFTPYVAAFLLRELQDTAKKSRFTEPLEIVDLIVDIMFIVDIIINFRTTYVNENDEACQVVSDPGKIATHYFKGWFIIDMVAAVPFD-LLLVSTNSDETTTLI------------GLLKTARLLRLVRVARKLDRYSEY--------GAAVLLLLMATFALIAHWLACIWYAIGSAELSHKEY---TWLHQLSKQLAQPYTSTNGTIPTGGPTLKSRYVTSLYFTLSTITSIGFGNVSATTDSEKIFTIIMMILGSLMYASVFGNVSAIIQRLYSGTARYHTEMSRLREFIRFHQIPNPLRQRLEEYFQHAW--SYTNGIDMNLVLKGFPDCLQADICLHLNRNLLSGCAAFAGS 424 HSP 2 Score: 48.9062 bits (115), Expect = 1.284e-33 Identity = 30/83 (36.14%), Postives = 47/83 (56.63%), Query Frame = 2 Query: 1781 PGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADT--RRVASVRAVTYCNVYSLDRESFLSVLEHYP 2023 PGD ++ G + + +YFI G V+I+ D + L FGE LL D + +VRA+TYC+++ + R+ L VL+ YP Sbjct: 443 PGDTLVHRGDILTGLYFIARGSVEILNDDNTVMGILGKDDIFGENPLLYDEVGKSSCNVRALTYCDLHKILRDDLLDVLDMYP 525
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Match: Ih (gene:FBgn0263397 transcript:FBtr0100369) HSP 1 Score: 526.554 bits (1355), Expect = 0.000e+0 Identity = 269/390 (68.97%), Postives = 327/390 (83.85%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNN--TNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEE--FFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 +LK Q+ S FQP DN+LAMKLFG++ AL+KE+ RQK GHW+IHPCSSFRFYWDL ML++LVANLI+LPVAISFFNDDLS RW+ FN +SDTIFL+DI VNFRTGI+ D A+++IL+PK IAKHY R+WF +D +SSIP+DYIFLI N ++ F Q +HAGRALRILRLAKLLSL+RLLRLSRLVRY+SQWEE F N AS F+ IFNL+ MMLL+GHW+ CLQFL+PM++ FP++ W+ L+E+ W +QY+W+LFKAMSHML IGYGRFPP S ++ W+T++SM++GATCYALF+GHA LIQS D+S+R YREK KQVEEYM YRKLPR +RQ+IT+Y+EHRYQG F+E IL ELSE LRE VINYNCR LVASVPFF NAD Sbjct: 704 FLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSF-QILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANAD 1092 HSP 2 Score: 168.703 bits (426), Expect = 0.000e+0 Identity = 75/105 (71.43%), Postives = 91/105 (86.67%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVS+VV KL YEVFQPGD IIKEGT+G++MYFIQEG+VDI+ +GE+ATSLSDGSYFGEICLL + RRVASVRA TYCN++SL + F VL+ YP+MR+TME+V Sbjct: 1095 FVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETV 1199
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Match: Ih (gene:FBgn0263397 transcript:FBtr0290109) HSP 1 Score: 525.398 bits (1352), Expect = 0.000e+0 Identity = 270/394 (68.53%), Postives = 326/394 (82.74%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNT---NHFS---QFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEE--FFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 +LK Q+ S FQP DN+LAMKLFG++ AL+KE+ RQK GHW+IHPCSSFRFYWDL ML++LVANLI+LPVAISFFNDDLS RW+ FN +SDTIFL+DI VNFRTGI+ D A+++IL+PK IAKHY R+WF +D +SSIP+DYIFLI N FS Q +HAGRALRILRLAKLLSL+RLLRLSRLVRY+SQWEE F N AS F+ IFNL+ MMLL+GHW+ CLQFL+PM++ FP++ W+ L+E+ W +QY+W+LFKAMSHML IGYGRFPP S ++ W+T++SM++GATCYALF+GHA LIQS D+S+R YREK KQVEEYM YRKLPR +RQ+IT+Y+EHRYQG F+E IL ELSE LRE VINYNCR LVASVPFF NAD Sbjct: 704 FLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANAD 1097 HSP 2 Score: 168.703 bits (426), Expect = 0.000e+0 Identity = 75/105 (71.43%), Postives = 91/105 (86.67%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVS+VV KL YEVFQPGD IIKEGT+G++MYFIQEG+VDI+ +GE+ATSLSDGSYFGEICLL + RRVASVRA TYCN++SL + F VL+ YP+MR+TME+V Sbjct: 1100 FVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETV 1204
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Match: Ih (gene:FBgn0263397 transcript:FBtr0308835) HSP 1 Score: 521.161 bits (1341), Expect = 0.000e+0 Identity = 269/390 (68.97%), Postives = 327/390 (83.85%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNN--TNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEE--FFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 +LK Q+ S FQP DN+LAMKLFG++ AL+KE+ RQK GHW+IHPCSSFRFYWDL ML++LVANLI+LPVAISFFNDDLS RW+ FN +SDTIFL+DI VNFRTGI+ D A+++IL+PK IAKHY R+WF +D +SSIP+DYIFLI N ++ F Q +HAGRALRILRLAKLLSL+RLLRLSRLVRY+SQWEE F N AS F+ IFNL+ MMLL+GHW+ CLQFL+PM++ FP++ W+ L+E+ W +QY+W+LFKAMSHML IGYGRFPP S ++ W+T++SM++GATCYALF+GHA LIQS D+S+R YREK KQVEEYM YRKLPR +RQ+IT+Y+EHRYQG F+E IL ELSE LRE VINYNCR LVASVPFF NAD Sbjct: 32 FLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSF-QILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANAD 420 HSP 2 Score: 165.622 bits (418), Expect = 0.000e+0 Identity = 75/105 (71.43%), Postives = 91/105 (86.67%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVS+VV KL YEVFQPGD IIKEGT+G++MYFIQEG+VDI+ +GE+ATSLSDGSYFGEICLL + RRVASVRA TYCN++SL + F VL+ YP+MR+TME+V Sbjct: 423 FVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETV 527
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Match: Ih (gene:FBgn0263397 transcript:FBtr0290292) HSP 1 Score: 521.161 bits (1341), Expect = 0.000e+0 Identity = 269/390 (68.97%), Postives = 327/390 (83.85%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNN--TNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEE--FFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 +LK Q+ S FQP DN+LAMKLFG++ AL+KE+ RQK GHW+IHPCSSFRFYWDL ML++LVANLI+LPVAISFFNDDLS RW+ FN +SDTIFL+DI VNFRTGI+ D A+++IL+PK IAKHY R+WF +D +SSIP+DYIFLI N ++ F Q +HAGRALRILRLAKLLSL+RLLRLSRLVRY+SQWEE F N AS F+ IFNL+ MMLL+GHW+ CLQFL+PM++ FP++ W+ L+E+ W +QY+W+LFKAMSHML IGYGRFPP S ++ W+T++SM++GATCYALF+GHA LIQS D+S+R YREK KQVEEYM YRKLPR +RQ+IT+Y+EHRYQG F+E IL ELSE LRE VINYNCR LVASVPFF NAD Sbjct: 15 FLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSF-QILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANAD 403 HSP 2 Score: 166.007 bits (419), Expect = 0.000e+0 Identity = 75/105 (71.43%), Postives = 91/105 (86.67%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVS+VV KL YEVFQPGD IIKEGT+G++MYFIQEG+VDI+ +GE+ATSLSDGSYFGEICLL + RRVASVRA TYCN++SL + F VL+ YP+MR+TME+V Sbjct: 406 FVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETV 510
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Match: Ih (gene:FBgn0263397 transcript:FBtr0308836) HSP 1 Score: 521.161 bits (1341), Expect = 0.000e+0 Identity = 269/390 (68.97%), Postives = 327/390 (83.85%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNN--TNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEE--FFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 +LK Q+ S FQP DN+LAMKLFG++ AL+KE+ RQK GHW+IHPCSSFRFYWDL ML++LVANLI+LPVAISFFNDDLS RW+ FN +SDTIFL+DI VNFRTGI+ D A+++IL+PK IAKHY R+WF +D +SSIP+DYIFLI N ++ F Q +HAGRALRILRLAKLLSL+RLLRLSRLVRY+SQWEE F N AS F+ IFNL+ MMLL+GHW+ CLQFL+PM++ FP++ W+ L+E+ W +QY+W+LFKAMSHML IGYGRFPP S ++ W+T++SM++GATCYALF+GHA LIQS D+S+R YREK KQVEEYM YRKLPR +RQ+IT+Y+EHRYQG F+E IL ELSE LRE VINYNCR LVASVPFF NAD Sbjct: 32 FLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQDFSDSF-QILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANAD 420 HSP 2 Score: 165.622 bits (418), Expect = 0.000e+0 Identity = 75/105 (71.43%), Postives = 91/105 (86.67%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVS+VV KL YEVFQPGD IIKEGT+G++MYFIQEG+VDI+ +GE+ATSLSDGSYFGEICLL + RRVASVRA TYCN++SL + F VL+ YP+MR+TME+V Sbjct: 423 FVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETV 527
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Match: hcn2b (hyperpolarization activated cyclic nucleotide-gated potassium channel 2b [Source:ZFIN;Acc:ZDB-GENE-030131-8228]) HSP 1 Score: 441.425 bits (1134), Expect = 5.298e-159 Identity = 223/390 (57.18%), Postives = 297/390 (76.15%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 Y++ Q ++ QPG NK ++++FG+Q A+ KE+ R K G+WIIHP S FRFYWD MLM +V NLI++PV I+FF ++ + W++FN VSDT FL+D+ +NFRTGI+ D EIIL+P++I K Y ++WF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ + +W + Y+++LFKAMSHML IGYGR P S S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQKI DYYEHRYQG MF+E IL+EL+E LRE+++N+NCR LVAS+P F NAD Sbjct: 81 YMQRQFSAMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKEETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYED-NTEIILDPEKIKKKYLKTWFVVDFVSSIPVDYIFLIVEKGID-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANAD 468 HSP 2 Score: 141.354 bits (355), Expect = 5.298e-159 Identity = 65/105 (61.90%), Postives = 81/105 (77.14%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G I LSDGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 471 FVTAMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 574
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Match: hcn2b (hyperpolarization activated cyclic nucleotide-gated potassium channel 2b [Source:ZFIN;Acc:ZDB-GENE-030131-8228]) HSP 1 Score: 437.958 bits (1125), Expect = 1.222e-157 Identity = 223/390 (57.18%), Postives = 297/390 (76.15%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 Y++ Q ++ QPG NK ++++FG+Q A+ KE+ R K G+WIIHP S FRFYWD MLM +V NLI++PV I+FF ++ + W++FN VSDT FL+D+ +NFRTGI+ D EIIL+P++I K Y ++WF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ + +W + Y+++LFKAMSHML IGYGR P S S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQKI DYYEHRYQG MF+E IL+EL+E LRE+++N+NCR LVAS+P F NAD Sbjct: 136 YMQRQFSAMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKEETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYED-NTEIILDPEKIKKKYLKTWFVVDFVSSIPVDYIFLIVEKGID-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANAD 523 HSP 2 Score: 139.813 bits (351), Expect = 1.222e-157 Identity = 65/105 (61.90%), Postives = 81/105 (77.14%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G I LSDGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 526 FVTAMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 629
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Match: hcn4 (hyperpolarization activated cyclic nucleotide-gated potassium channel 4 [Source:ZFIN;Acc:ZDB-GENE-050420-360]) HSP 1 Score: 452.595 bits (1163), Expect = 3.425e-145 Identity = 235/421 (55.82%), Postives = 307/421 (72.92%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 ++ Q ++ QPG NK ++++FG++ A+ +E+ R K G WIIHP S FRFYWDL ML+++V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI+ D A EIIL+P+QI Y RSWF++DF+SSIPVDYIFLI+ T S F RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP DCW+ K + W QY+++LFKAMSHML IGYG +PP ++ W+TI+SM+ GATCYA+FVGHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQ+I DYYEHRYQG MF+E IL EL+E LRE++IN+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 174 FMHRQFGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDEHTPPWIVFNVVSDTFFLMDLVLNFRTGIVKEDNA-EIILDPQQIKIKYLRSWFVVDFISSIPVDYIFLIVE-TRIDSDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPADCWVAKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKK 592 HSP 2 Score: 142.51 bits (358), Expect = 1.150e-34 Identity = 65/105 (61.90%), Postives = 81/105 (77.14%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G T LSDGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 564 FVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 667
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Match: hcn4l (hyperpolarization activated cyclic nucleotide-gated potassium channel 4l [Source:ZFIN;Acc:ZDB-GENE-110411-3]) HSP 1 Score: 444.891 bits (1143), Expect = 1.511e-143 Identity = 233/420 (55.48%), Postives = 305/420 (72.62%), Query Frame = 3 Query: 576 LKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 LK + + PG NK ++++FG++ A+ E+ R K G WIIHP S FRFYWDL+ML+++V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI+ D + EIIL+P+QI Y RSWF +DFLSSIPVDYIFLI+ T S F RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ K + W QY+++LFKAMSHML IGYG +PP ++ W+TI+SM+ GATCYA+FVGHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQ+I DYYEHRYQG MF+E IL EL+E LRE++I++NCR LVA++P F NAD L+ + F RE ++ KK Sbjct: 18 LKRHLFTFLLPGVNKFSLRMFGSEKAVEHEQERVKSAGFWIIHPYSDFRFYWDLIMLLLMVGNLIIIPVGITFFKDEHTPAWIVFNVVSDTFFLVDLVLNFRTGIVKED-STEIILDPQQIKVRYLRSWFAVDFLSSIPVDYIFLIVE-TRIDSDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVAKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIISFNCRKLVATMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTVGKK 435 HSP 2 Score: 140.198 bits (352), Expect = 7.154e-34 Identity = 64/105 (60.95%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGTVG +MYFIQ G++ ++TK G T +SDGSYFGEICLL RR ASVRA TYC +YSL + F VLE YP+MRR E+V Sbjct: 407 FVTSMLTKLRFEVFQPGDYIIREGTVGKKMYFIQHGVLTVLTK-GSKETKISDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFETV 510
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Match: hcn1 (hyperpolarization activated cyclic nucleotide-gated potassium channel 1 [Source:ZFIN;Acc:ZDB-GENE-110520-1]) HSP 1 Score: 439.499 bits (1129), Expect = 1.990e-142 Identity = 228/421 (54.16%), Postives = 310/421 (73.63%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 +++ Q ++ QPG NK ++++FG+Q A+ KE+ R + G+WIIHP S FRFYWDL+ML++++ NLI++PV I+FF++ + WLVFN SDTIFL+D+ +NFRTGI+ N+ + EIIL+PK I +Y +SWF++DFLSSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + IFNL+ MMLLL HW+ CLQFL+P++++FP DCW+ + +W QY+++LFKAMSHML IGYG P S S+ W+T++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQKI DYYEHRYQG +F+E IL EL++ L+E+++N+NCR LVA++P F NAD LS + F RE ++ KK Sbjct: 70 FMQRQFGAMMQPGVNKFSLRMFGSQKAVEKEQERVQTAGYWIIHPYSDFRFYWDLIMLIMMMGNLIIIPVGITFFSEQTTTSWLVFNVASDTIFLVDLVMNFRTGIV-NEESSEIILDPKVIKMNYLKSWFVVDFLSSIPVDYIFLIVEK-GFDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNGMVNDSWGKQYSYALFKAMSHMLCIGYGARAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEDSILNELNDPLKEEIVNFNCRKLVATMPLFANADPNFVTGMLSKLKFEVFQPNDYIIREGTVGKK 488 HSP 2 Score: 129.028 bits (323), Expect = 1.878e-30 Identity = 62/106 (58.49%), Postives = 79/106 (74.53%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITK-DGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQP D+II+EGTVG +MYFIQ G+ +ITK + E+ L+DGSYFGEICLL RR ASVRA TYC ++SL + F VLE YP+MRR E+V Sbjct: 460 FVTGMLSKLKFEVFQPNDYIIREGTVGKKMYFIQHGVASVITKFNKEL--KLTDGSYFGEICLLTKGRRTASVRADTYCRLFSLSVDHFNEVLEEYPMMRRAFETV 563
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Match: ENSXETT00000054880.1 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [Source:NCBI gene;Acc:100495521]) HSP 1 Score: 441.039 bits (1133), Expect = 1.796e-158 Identity = 227/390 (58.21%), Postives = 298/390 (76.41%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 ++ Q +L QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWDL ML+++V NLI++PV I+FF ++ + W+VFN VSDT FL+D+ +NFRTGI+L D EIIL P++I Y +SWF++DF+SSIPVDYIFLI+ T S+ RALRI+R AK+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP DCW+ +++ A+W QY+++LFKAMSHML IGYG+ P + W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP LRQ+I DYYEHRYQG MF+E IL ELSE LRE++IN+NCR LVAS+P F NAD Sbjct: 73 FMHRQFGALLQPGVNKFSLRMFGSQKAVEREQDRVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKEENTPAWIVFNVVSDTFFLVDLVLNFRTGIVLED-NTEIILEPQRIKIRYLKSWFLVDFVSSIPVDYIFLIVE-TRIDSEVYKTARALRIVRFAKVLSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPEDCWVSLNHMQNASWGKQYSYALFKAMSHMLCIGYGQQAPVGMGDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANAD 460 HSP 2 Score: 140.198 bits (352), Expect = 1.796e-158 Identity = 65/105 (61.90%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD++I+EGTVG +M+FIQ G+V I++K G T LSDGSYFGEICLL RR ASVRA TYC +YSL + F VLE YP+MRR ESV Sbjct: 463 FVTSMLTKLRFEVFQPGDYLIREGTVGKKMFFIQHGVVSILSK-GSKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFESV 566
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Match: ENSXETT00000054882.1 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [Source:NCBI gene;Acc:100495521]) HSP 1 Score: 441.039 bits (1133), Expect = 1.935e-158 Identity = 227/390 (58.21%), Postives = 298/390 (76.41%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 ++ Q +L QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWDL ML+++V NLI++PV I+FF ++ + W+VFN VSDT FL+D+ +NFRTGI+L D EIIL P++I Y +SWF++DF+SSIPVDYIFLI+ T S+ RALRI+R AK+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP DCW+ +++ A+W QY+++LFKAMSHML IGYG+ P + W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP LRQ+I DYYEHRYQG MF+E IL ELSE LRE++IN+NCR LVAS+P F NAD Sbjct: 178 FMHRQFGALLQPGVNKFSLRMFGSQKAVEREQDRVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKEENTPAWIVFNVVSDTFFLVDLVLNFRTGIVLED-NTEIILEPQRIKIRYLKSWFLVDFVSSIPVDYIFLIVE-TRIDSEVYKTARALRIVRFAKVLSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPEDCWVSLNHMQNASWGKQYSYALFKAMSHMLCIGYGQQAPVGMGDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANAD 565 HSP 2 Score: 140.198 bits (352), Expect = 1.935e-158 Identity = 65/105 (61.90%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD++I+EGTVG +M+FIQ G+V I++K G T LSDGSYFGEICLL RR ASVRA TYC +YSL + F VLE YP+MRR ESV Sbjct: 568 FVTSMLTKLRFEVFQPGDYLIREGTVGKKMFFIQHGVVSILSK-GSKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFESV 671
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Match: ENSXETT00000054879.1 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [Source:NCBI gene;Acc:100495521]) HSP 1 Score: 440.654 bits (1132), Expect = 1.439e-157 Identity = 227/390 (58.21%), Postives = 298/390 (76.41%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 ++ Q +L QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWDL ML+++V NLI++PV I+FF ++ + W+VFN VSDT FL+D+ +NFRTGI+L D EIIL P++I Y +SWF++DF+SSIPVDYIFLI+ T S+ RALRI+R AK+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP DCW+ +++ A+W QY+++LFKAMSHML IGYG+ P + W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP LRQ+I DYYEHRYQG MF+E IL ELSE LRE++IN+NCR LVAS+P F NAD Sbjct: 26 FMHRQFGALLQPGVNKFSLRMFGSQKAVEREQDRVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKEENTPAWIVFNVVSDTFFLVDLVLNFRTGIVLED-NTEIILEPQRIKIRYLKSWFLVDFVSSIPVDYIFLIVE-TRIDSEVYKTARALRIVRFAKVLSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPEDCWVSLNHMQNASWGKQYSYALFKAMSHMLCIGYGQQAPVGMGDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANAD 413 HSP 2 Score: 137.502 bits (345), Expect = 1.439e-157 Identity = 65/105 (61.90%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD++I+EGTVG +M+FIQ G+V I++K G T LSDGSYFGEICLL RR ASVRA TYC +YSL + F VLE YP+MRR ESV Sbjct: 416 FVTSMLTKLRFEVFQPGDYLIREGTVGKKMFFIQHGVVSILSK-GSKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFESV 519
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Match: ENSXETT00000054883.1 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [Source:NCBI gene;Acc:100495521]) HSP 1 Score: 440.654 bits (1132), Expect = 1.616e-157 Identity = 227/390 (58.21%), Postives = 298/390 (76.41%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 ++ Q +L QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWDL ML+++V NLI++PV I+FF ++ + W+VFN VSDT FL+D+ +NFRTGI+L D EIIL P++I Y +SWF++DF+SSIPVDYIFLI+ T S+ RALRI+R AK+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP DCW+ +++ A+W QY+++LFKAMSHML IGYG+ P + W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP LRQ+I DYYEHRYQG MF+E IL ELSE LRE++IN+NCR LVAS+P F NAD Sbjct: 48 FMHRQFGALLQPGVNKFSLRMFGSQKAVEREQDRVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKEENTPAWIVFNVVSDTFFLVDLVLNFRTGIVLED-NTEIILEPQRIKIRYLKSWFLVDFVSSIPVDYIFLIVE-TRIDSEVYKTARALRIVRFAKVLSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPEDCWVSLNHMQNASWGKQYSYALFKAMSHMLCIGYGQQAPVGMGDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANAD 435 HSP 2 Score: 137.887 bits (346), Expect = 1.616e-157 Identity = 65/105 (61.90%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD++I+EGTVG +M+FIQ G+V I++K G T LSDGSYFGEICLL RR ASVRA TYC +YSL + F VLE YP+MRR ESV Sbjct: 438 FVTSMLTKLRFEVFQPGDYLIREGTVGKKMFFIQHGVVSILSK-GSKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFESV 541
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Match: ENSXETT00000054881.1 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [Source:NCBI gene;Acc:100495521]) HSP 1 Score: 439.884 bits (1130), Expect = 3.447e-157 Identity = 227/390 (58.21%), Postives = 298/390 (76.41%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 ++ Q +L QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWDL ML+++V NLI++PV I+FF ++ + W+VFN VSDT FL+D+ +NFRTGI+L D EIIL P++I Y +SWF++DF+SSIPVDYIFLI+ T S+ RALRI+R AK+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP DCW+ +++ A+W QY+++LFKAMSHML IGYG+ P + W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP LRQ+I DYYEHRYQG MF+E IL ELSE LRE++IN+NCR LVAS+P F NAD Sbjct: 40 FMHRQFGALLQPGVNKFSLRMFGSQKAVEREQDRVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKEENTPAWIVFNVVSDTFFLVDLVLNFRTGIVLED-NTEIILEPQRIKIRYLKSWFLVDFVSSIPVDYIFLIVE-TRIDSEVYKTARALRIVRFAKVLSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPEDCWVSLNHMQNASWGKQYSYALFKAMSHMLCIGYGQQAPVGMGDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADLRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANAD 427 HSP 2 Score: 137.502 bits (345), Expect = 3.447e-157 Identity = 65/105 (61.90%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD++I+EGTVG +M+FIQ G+V I++K G T LSDGSYFGEICLL RR ASVRA TYC +YSL + F VLE YP+MRR ESV Sbjct: 430 FVTSMLTKLRFEVFQPGDYLIREGTVGKKMFFIQHGVVSILSK-GSKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFESV 533
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Match: Hcn2 (hyperpolarization-activated, cyclic nucleotide-gated K+ 2 [Source:MGI Symbol;Acc:MGI:1298210]) HSP 1 Score: 441.039 bits (1133), Expect = 1.463e-143 Identity = 233/429 (54.31%), Postives = 310/429 (72.26%), Query Frame = 3 Query: 549 HPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 PR S + +L+ Q +L QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWD ML+ +V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI++ D EIIL+P++I K Y R+WF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ N+ +W + Y+++LFKAMSHML IGYGR P S ++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQKI DYYEHRYQG MF+E IL EL+ LRE+++N+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 127 EPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIED-NTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGID-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKK 553 HSP 2 Score: 137.502 bits (345), Expect = 4.851e-33 Identity = 64/105 (60.95%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G LSDGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 525 FVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 628
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Match: Hcn2 (hyperpolarization-activated, cyclic nucleotide-gated K+ 2 [Source:MGI Symbol;Acc:MGI:1298210]) HSP 1 Score: 441.039 bits (1133), Expect = 1.463e-143 Identity = 233/429 (54.31%), Postives = 310/429 (72.26%), Query Frame = 3 Query: 549 HPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 PR S + +L+ Q +L QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWD ML+ +V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI++ D EIIL+P++I K Y R+WF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ N+ +W + Y+++LFKAMSHML IGYGR P S ++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQKI DYYEHRYQG MF+E IL EL+ LRE+++N+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 127 EPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIED-NTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGID-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKK 553 HSP 2 Score: 137.502 bits (345), Expect = 4.851e-33 Identity = 64/105 (60.95%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G LSDGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 525 FVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 628
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Match: Hcn4 (hyperpolarization-activated, cyclic nucleotide-gated K+ 4 [Source:MGI Symbol;Acc:MGI:1298209]) HSP 1 Score: 446.432 bits (1147), Expect = 4.119e-142 Identity = 234/427 (54.80%), Postives = 310/427 (72.60%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 RL S +++ Q ++ QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWDL ML+++V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI++ D EIIL+P++I Y +SWF++DF+SSIPVDYIFLI+ T S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ + +W QY+++LFKAMSHML IGYGR P S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQ+I DYYEHRYQG MF+E IL ELSE LRE++IN+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 207 RLGQSGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVED-NTEIILDPQRIKMKYLKSWFVVDFISSIPVDYIFLIVE-TRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSINGMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKK 631 HSP 2 Score: 141.354 bits (355), Expect = 3.086e-34 Identity = 64/105 (60.95%), Postives = 81/105 (77.14%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G T L+DGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 603 FVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 706
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Match: Hcn1 (hyperpolarization activated cyclic nucleotide gated potassium channel 1 [Source:MGI Symbol;Acc:MGI:1096392]) HSP 1 Score: 437.187 bits (1123), Expect = 1.690e-141 Identity = 227/421 (53.92%), Postives = 308/421 (73.16%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 +++ Q S+ QPG NK ++++FG+Q A+ KE+ R K G WIIHP S FRFYWDL+ML+++V NL+++PV I+FF + + W++FN SDT+FLLD+ +NFRTG + N+ + EIIL+PK I +Y +SWF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + IFNL+ MMLLL HW+ CLQFL+P++++FP DCW+ + +W QY+++LFKAMSHML IGYG P S S+ W+T++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQKI DYYEHRYQG +F+E +IL EL++ LRE+++N+NCR LVA++P F NAD LS + F RE ++ KK Sbjct: 82 FMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTV-NEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMD-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKK 500 HSP 2 Score: 133.265 bits (334), Expect = 1.116e-31 Identity = 62/105 (59.05%), Postives = 78/105 (74.29%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EG VG +MYFIQ G+ +ITK + L+DGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 472 FVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSK-EMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 575
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Match: Hcn3 (hyperpolarization-activated, cyclic nucleotide-gated K+ 3 [Source:MGI Symbol;Acc:MGI:1298211]) HSP 1 Score: 423.705 bits (1088), Expect = 7.254e-138 Identity = 225/426 (52.82%), Postives = 301/426 (70.66%), Query Frame = 3 Query: 561 SASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHF-SQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 SA + Q+ +L QP NK ++++FG+ A+ E+ R K G WIIHP S FRFYWDL+ML+++V NLIVLPV I+FF ++ S W+VFN +SDT FLLD+ +NFRTGI++ + A EI+L P+ I Y R+WF++D +SSIPVDYIFL++ ++ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + IFNL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ + +W QY+ +LFKAMSHML IGYG+ P + W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQ+I +YYEHRYQG MF+E IL ELSE LRE++IN+ CRGLVA +P F +AD L+ + F RE S+ +K Sbjct: 39 SAPEPKRRQLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGA-EILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRK 463 HSP 2 Score: 130.568 bits (327), Expect = 6.431e-31 Identity = 59/105 (56.19%), Postives = 79/105 (75.24%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ V+ KL +EVFQPGD +++EG+VG +MYFIQ G++ ++ + G T L+DGSYFGEICLL RR ASVRA TYC +YSL + F +VLE +P+MRR E+V Sbjct: 435 FVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLAR-GARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETV 538
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Match: sp|O88703|HCN2_MOUSE (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Mus musculus OX=10090 GN=Hcn2 PE=1 SV=1) HSP 1 Score: 441.039 bits (1133), Expect = 1.023e-142 Identity = 233/429 (54.31%), Postives = 310/429 (72.26%), Query Frame = 3 Query: 549 HPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 PR S + +L+ Q +L QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWD ML+ +V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI++ D EIIL+P++I K Y R+WF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ N+ +W + Y+++LFKAMSHML IGYGR P S ++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQKI DYYEHRYQG MF+E IL EL+ LRE+++N+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 127 EPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIED-NTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGID-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKK 553 HSP 2 Score: 137.502 bits (345), Expect = 3.393e-32 Identity = 64/105 (60.95%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G LSDGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 525 FVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 628
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Match: sp|Q9JKA9|HCN2_RAT (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Rattus norvegicus OX=10116 GN=Hcn2 PE=1 SV=3) HSP 1 Score: 440.654 bits (1132), Expect = 1.602e-142 Identity = 233/429 (54.31%), Postives = 310/429 (72.26%), Query Frame = 3 Query: 549 HPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 PR S + +L+ Q +L QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWD ML+ +V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI++ D EIIL+P++I K Y R+WF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ N+ +W + Y+++LFKAMSHML IGYGR P S ++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQKI DYYEHRYQG MF+E IL EL+ LRE+++N+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 127 EPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIED-NTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGID-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKK 553 HSP 2 Score: 137.117 bits (344), Expect = 3.454e-32 Identity = 64/105 (60.95%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G LSDGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 525 FVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 628
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Match: sp|Q9TV66|HCN4_RABIT (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 OS=Oryctolagus cuniculus OX=9986 GN=HCN4 PE=2 SV=1) HSP 1 Score: 447.588 bits (1150), Expect = 5.298e-142 Identity = 238/442 (53.85%), Postives = 316/442 (71.49%), Query Frame = 3 Query: 525 GGGAPGYR-----HPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 GG A G + RL + +++ Q ++ QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWDL ML+++V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI++ D D IIL+P++I Y +SWF++DF+SSIPVDYIFLI+ T S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ N+ +W QY+++LFKAMSHML IGYGR P S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQ+I DYYEHRYQG MF+E IL ELSE LRE++IN+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 193 GGAAAGDQILPEAEARLGQAGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNTD-IILDPRRIKMKYLKSWFVVDFVSSIPVDYIFLIVE-TRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSLNNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPMGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKK 632 HSP 2 Score: 141.354 bits (355), Expect = 2.123e-33 Identity = 64/105 (60.95%), Postives = 81/105 (77.14%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G T L+DGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 604 FVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 707
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Match: sp|Q9MZS1|HCN1_RABIT (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 OS=Oryctolagus cuniculus OX=9986 GN=HCN1 PE=2 SV=2) HSP 1 Score: 437.958 bits (1125), Expect = 7.065e-142 Identity = 227/421 (53.92%), Postives = 308/421 (73.16%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 +++ Q S+ QPG NK ++++FG+Q A+ KE+ R K G WIIHP S FRFYWDL+ML+++V NL+++PV I+FF + + W++FN SDT+FLLD+ +NFRTG + N+ + EIIL+PK I +Y +SWF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + IFNL+ MMLLL HW+ CLQFL+P++++FP DCW+ + +W QY+++LFKAMSHML IGYG P S S+ W+T++SM+ GATCYA+FVGHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQKI DYYEHRYQG +F+E +IL EL++ LRE+++N+NCR LVA++P F NAD LS + F RE ++ KK Sbjct: 29 FMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTV-NEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMD-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKK 447 HSP 2 Score: 133.265 bits (334), Expect = 6.291e-31 Identity = 62/105 (59.05%), Postives = 78/105 (74.29%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EG VG +MYFIQ G+ +ITK + L+DGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 419 FVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSK-EMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 522
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Match: sp|Q9Y3Q4|HCN4_HUMAN (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 OS=Homo sapiens OX=9606 GN=HCN4 PE=1 SV=1) HSP 1 Score: 447.973 bits (1151), Expect = 7.422e-142 Identity = 234/427 (54.80%), Postives = 311/427 (72.83%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 RL + +++ Q ++ QPG NK ++++FG+Q A+ +E+ R K G WIIHP S FRFYWDL ML+++V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI++ D EIIL+P++I Y +SWF++DF+SSIPVDYIFLI+ T S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ N+ +W QY+++LFKAMSHML IGYGR P S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQ+I DYYEHRYQG MF+E IL ELSE LRE++IN+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 207 RLGQAGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVED-NTEIILDPQRIKMKYLKSWFMVDFISSIPVDYIFLIVE-TRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSINNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKK 631 HSP 2 Score: 141.354 bits (355), Expect = 2.161e-33 Identity = 64/105 (60.95%), Postives = 81/105 (77.14%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGT+G +MYFIQ G+V ++TK G T L+DGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 603 FVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 706
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Match: A0A267GGH4 (Cyclic nucleotide-binding domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003625g4 PE=4 SV=1) HSP 1 Score: 597.816 bits (1540), Expect = 0.000e+0 Identity = 298/393 (75.83%), Postives = 342/393 (87.02%), Query Frame = 3 Query: 552 PRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 P+ S S YLKEQ + FQP DNKLAMKLFG ++ALLKEK RQ++ G WIIHPCS+FRFYWDLLML++L+ NL+VLPVAISFFNDDLS +W++FN VSDTIFL DI VNFRTG+I NDFA+EI+L+PK IA+HY +SWF +D +SSIP+DYIFL+LN N+ SQ MHAGRALRILRLAKLLSLLRLLRLSRLVRY+SQWEEFF ASK GI LVL+M+LLGHWNAC QFLIP + +FP D W+ K LKEA+WF QYTW+LFKAMSHMLSIGYG+ PPTS SEAW+TIVSMMTG++CYALFVGHAAALIQS+DTSKRLYREK+KQVEEYM YRKLPR LRQ+I +YYEHRYQG MFNE DIL ELSECLRE++INYNCR LVA+VPFF AD Sbjct: 291 PKQSTSSYLKEQFFAFFQPSDNKLAMKLFGNKNALLKEKRRQQQSGKWIIHPCSNFRFYWDLLMLVLLITNLVVLPVAISFFNDDLSPQWIIFNCVSDTIFLSDIAVNFRTGVITNDFAEEIVLDPKMIAQHYMKSWFFLDLISSIPMDYIFLVLNQRNNMSQLMHAGRALRILRLAKLLSLLRLLRLSRLVRYVSQWEEFFQIASKCFGIIKLVLIMMLLGHWNACFQFLIPFLNDFPPDSWVAKRGLKEAHWFRQYTWALFKAMSHMLSIGYGQHPPTSISEAWITIVSMMTGSSCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFNENDILSELSECLREQIINYNCRALVAAVPFFTYAD 683 HSP 2 Score: 190.66 bits (483), Expect = 0.000e+0 Identity = 86/105 (81.90%), Postives = 99/105 (94.29%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVSEVV +L YEVFQPGD IIKEGT+G++MYFIQEGIVDIIT+DGE+ATSLSDGSYFGEICLL + RRVASVRA TYCN+YSL+RE+FLSVL++YP+MRRTMESV Sbjct: 686 FVSEVVTRLKYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITRDGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLYSLERENFLSVLDNYPLMRRTMESV 790
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Match: A0A267GPW9 (Cyclic nucleotide-binding domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003625g3 PE=4 SV=1) HSP 1 Score: 597.816 bits (1540), Expect = 0.000e+0 Identity = 298/393 (75.83%), Postives = 342/393 (87.02%), Query Frame = 3 Query: 552 PRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 P+ S S YLKEQ + FQP DNKLAMKLFG ++ALLKEK RQ++ G WIIHPCS+FRFYWDLLML++L+ NL+VLPVAISFFNDDLS +W++FN VSDTIFL DI VNFRTG+I NDFA+EI+L+PK IA+HY +SWF +D +SSIP+DYIFL+LN N+ SQ MHAGRALRILRLAKLLSLLRLLRLSRLVRY+SQWEEFF ASK GI LVL+M+LLGHWNAC QFLIP + +FP D W+ K LKEA+WF QYTW+LFKAMSHMLSIGYG+ PPTS SEAW+TIVSMMTG++CYALFVGHAAALIQS+DTSKRLYREK+KQVEEYM YRKLPR LRQ+I +YYEHRYQG MFNE DIL ELSECLRE++INYNCR LVA+VPFF AD Sbjct: 295 PKQSTSSYLKEQFFAFFQPSDNKLAMKLFGNKNALLKEKRRQQQSGKWIIHPCSNFRFYWDLLMLVLLITNLVVLPVAISFFNDDLSPQWIIFNCVSDTIFLSDIAVNFRTGVITNDFAEEIVLDPKMIAQHYMKSWFFLDLISSIPMDYIFLVLNQRNNMSQLMHAGRALRILRLAKLLSLLRLLRLSRLVRYVSQWEEFFQIASKCFGIIKLVLIMMLLGHWNACFQFLIPFLNDFPPDSWVAKRGLKEAHWFRQYTWALFKAMSHMLSIGYGQHPPTSISEAWITIVSMMTGSSCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFNENDILSELSECLREQIINYNCRALVAAVPFFTYAD 687 HSP 2 Score: 191.045 bits (484), Expect = 0.000e+0 Identity = 86/105 (81.90%), Postives = 99/105 (94.29%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVSEVV +L YEVFQPGD IIKEGT+G++MYFIQEGIVDIIT+DGE+ATSLSDGSYFGEICLL + RRVASVRA TYCN+YSL+RE+FLSVL++YP+MRRTMESV Sbjct: 690 FVSEVVTRLKYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITRDGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLYSLERENFLSVLDNYPLMRRTMESV 794
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Match: A0A4Z2DGN8 (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_001166 PE=4 SV=1) HSP 1 Score: 597.43 bits (1539), Expect = 0.000e+0 Identity = 292/392 (74.49%), Postives = 344/392 (87.76%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 + S S YLKEQ + FQP DNKLAMKLFG+++ALLKEK RQ + G W+IHPCS+FRFYWDLLMLM+L+ANLI+LPVAISFFNDDLS W++FN +SD +F+ DI V FRTG++ ND+ADEIILNPK+IA+HY +SWF++DF+SSIP+DY++LI N +H++QF AGR LRILRLAKLLS+LRLLRL+RLVRY+SQWEEF N ASKF+GIFNLVL+MLLLGHWNACLQ+LIPM+ EFP D W+ +C L+ A+WF QYTW+LFKAMSHMLSIGYGRFPPTS EAW+TIVSMM+GATCYALFVGHAAALIQS+DTSKRLYREK+KQVEEYM YRKLPR LRQ+I +YYEHRYQG MF+E IL E SECLRE+VINYNCR LVA+VPFF AD Sbjct: 592 KQSTSSYLKEQFQAFFQPSDNKLAMKLFGSKNALLKEKRRQVQQGKWVIHPCSNFRFYWDLLMLMLLIANLIILPVAISFFNDDLSIHWIIFNSISDVVFIADIAVKFRTGVVANDYADEIILNPKEIARHYLKSWFVLDFISSIPMDYLYLIFNKKDHYNQFFSAGRTLRILRLAKLLSMLRLLRLTRLVRYVSQWEEFLNIASKFMGIFNLVLLMLLLGHWNACLQYLIPMLMEFPPDSWVKRCKLENADWFQQYTWALFKAMSHMLSIGYGRFPPTSIGEAWITIVSMMSGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEAQILNEFSECLREQVINYNCRALVAAVPFFTYAD 983 HSP 2 Score: 187.193 bits (474), Expect = 0.000e+0 Identity = 87/105 (82.86%), Postives = 97/105 (92.38%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVSEVV KL +EVFQPGD IIKEGT+G++MYFIQEGIVDIITKDGE+ATSLSDGSYFGEI LL + RRVASV+AV Y N+YSLDRESFLSVLE+YP+MRRTMESV Sbjct: 986 FVSEVVTKLKFEVFQPGDLIIKEGTIGNKMYFIQEGIVDIITKDGEVATSLSDGSYFGEITLLTNARRVASVKAVVYSNLYSLDRESFLSVLENYPLMRRTMESV 1090
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Match: A0A158QHD6 (Cyclic nucleotide-binding domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS7251 PE=4 SV=1) HSP 1 Score: 594.734 bits (1532), Expect = 0.000e+0 Identity = 307/447 (68.68%), Postives = 365/447 (81.66%), Query Frame = 3 Query: 468 TPKDNDDGTQSEQSLSEYIGGGAP----GYRH-----PRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN 1781 T + ND G +++ S+ I A GY + S S YLKEQ + FQP DNKLAMKLFG++SAL KEK RQ++HG WIIHPCSSFRFYWDLLML +L+ANLI+LPVAISFFNDDL +W+VFN VSD +F+ DI V FRTGII ND+AD+IIL+PK+IA+ Y RSWF++DF+SSIP+DYIF +LN ++Q AGR LRILRLAKLLS++RLLRLSRLVRY+SQWEEF N ASKF+GIFNLVL+MLLLGHWNACLQFLIP++ ++P D W+ +C L++A+WF+QYTW+LFKAMSHMLSIGYGRFPPTS SEAW+TIVSMMTGATCYALFVGHAAALIQS+DTSKRLYREK+KQVEEYM YRKLPR LRQ+I DYYEHRYQG MF+E ILQELSECLRE++INYNCR LVA+VPFF AD + ++N + F Sbjct: 385 TSQTNDTGLEAQASVESQIPSNAAAMADGYVEELCDPSKQSTSSYLKEQFFAFFQPSDNKLAMKLFGSKSALNKEKRRQQQHGKWIIHPCSSFRFYWDLLMLTLLIANLIILPVAISFFNDDLRPQWVVFNTVSDAVFIADIVVKFRTGIITNDYADDIILDPKEIARQYVRSWFLLDFISSIPLDYIFRVLNKHESYNQIFSAGRTLRILRLAKLLSMIRLLRLSRLVRYVSQWEEFLNIASKFMGIFNLVLLMLLLGHWNACLQFLIPLLMDYPEDSWVQRCRLRDADWFEQYTWALFKAMSHMLSIGYGRFPPTSISEAWITIVSMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIADYYEHRYQGKMFDEAQILQELSECLREQIINYNCRELVAAVPFFTYADQDFVSEMVANLKFEVFQ 831 HSP 2 Score: 107.457 bits (267), Expect = 2.934e-20 Identity = 49/63 (77.78%), Postives = 56/63 (88.89%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLL 1924 FVSE+V L +EVFQPGD IIKEGT+G++MYFIQEGIVDIITKDGEIAT+LSDGSYFG + L Sbjct: 817 FVSEMVANLKFEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEIATTLSDGSYFGGMSFL 879
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Match: A0A3Q0KVG7 (Cyclic nucleotide-binding domain-containing protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 593.578 bits (1529), Expect = 0.000e+0 Identity = 293/392 (74.74%), Postives = 344/392 (87.76%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 + S S YLKEQ + FQP DNKLAMKLFG+++ALLKEK RQ + G W+IHPCS+FRFYWDLLMLM+L+ANLI+LPVAISFFNDDLS W++FN +SD +F+ DI V FRTGI+ ND+ADEIILNPK+IA+HY +SWFI+DF+SSIP+DY++LI N +H++QF AGR LRILRLAKLLS+LRLLRL+RLVRY+SQWEEF N ASKF+GIFNLVL+MLLLGHWNACLQ+LIPM+ +FP D W+ +C L+ A+WF QYTW+LFKAMSHMLSIGYGRFPPTS EAW+TIVSMM+GATCYALFVGHAAALIQS+DTSKRLYREK+KQVEEYM YRKLPR LRQ+I +YYEHRYQG MF+E IL E SECLRE+VINYNCR LVA+VPFF AD Sbjct: 596 KQSTSSYLKEQFQAFFQPSDNKLAMKLFGSKNALLKEKRRQVQQGKWVIHPCSNFRFYWDLLMLMLLIANLIILPVAISFFNDDLSIHWIIFNSISDVVFIADIAVKFRTGIVTNDYADEIILNPKEIARHYLKSWFILDFISSIPMDYLYLIFNKKDHYNQFFSAGRTLRILRLAKLLSMLRLLRLTRLVRYVSQWEEFLNIASKFMGIFNLVLLMLLLGHWNACLQYLIPMLMDFPPDSWVKRCKLENADWFQQYTWALFKAMSHMLSIGYGRFPPTSIGEAWITIVSMMSGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEAQILNEFSECLREQVINYNCRALVAAVPFFTYAD 987 HSP 2 Score: 187.578 bits (475), Expect = 0.000e+0 Identity = 87/105 (82.86%), Postives = 97/105 (92.38%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVSEVV KL +EVFQPGD IIKEGT+G++MYFIQEGIVDIITKDGE+ATSLSDGSYFGEI LL +TRR ASV+AV Y N+YSLDRESFLSVLE+YP+MRRTMESV Sbjct: 990 FVSEVVTKLKFEVFQPGDLIIKEGTIGNKMYFIQEGIVDIITKDGEVATSLSDGSYFGEITLLTNTRRTASVKAVVYSNLYSLDRESFLSVLENYPLMRRTMESV 1094
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Match: hcn4l (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3-like [Source:NCBI gene;Acc:103030119]) HSP 1 Score: 448.743 bits (1153), Expect = 5.453e-161 Identity = 227/396 (57.32%), Postives = 301/396 (76.01%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 RL + ++ Q+ ++ QPG NK ++++FG++ A+ +E+ R K G WIIHP S FRFYWDL+ML+++V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI+ D + EIIL+P+ I Y RSWF +DF+SSIPVDYIFLI+ T S F RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ K + W QY+++LFKAMSHML IGYG +PP ++ W+TI+SM+ GATCYA+FVGHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQ+I DYYEHRYQG MF+E IL EL+E LRE++I++NCR LVA++P F NAD Sbjct: 155 RLYQAGFMHRQLGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLIMLLLMVGNLIIIPVGITFFKDEHTPAWIVFNVVSDTFFLVDLVLNFRTGIVKED-STEIILDPQLIKVRYLRSWFAVDFISSIPVDYIFLIVE-TRIDSDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIISFNCRKLVATMPLFANAD 548 HSP 2 Score: 140.198 bits (352), Expect = 5.453e-161 Identity = 64/105 (60.95%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGTVG +MYFIQ G++ ++TK G T +SDGSYFGEICLL RR ASVRA TYC +YSL + F VLE YP+MRR E+V Sbjct: 551 FVTSMLTKLRFEVFQPGDYIIREGTVGKKMYFIQHGVLTVLTK-GSKETKISDGSYFGEICLLTRGRRTASVRAETYCRLYSLSVDHFNEVLEEYPMMRRAFETV 654
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Match: hcn4l (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3-like [Source:NCBI gene;Acc:103030119]) HSP 1 Score: 448.358 bits (1152), Expect = 6.439e-161 Identity = 227/396 (57.32%), Postives = 301/396 (76.01%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 RL + ++ Q+ ++ QPG NK ++++FG++ A+ +E+ R K G WIIHP S FRFYWDL+ML+++V NLI++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI+ D + EIIL+P+ I Y RSWF +DF+SSIPVDYIFLI+ T S F RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ K + W QY+++LFKAMSHML IGYG +PP ++ W+TI+SM+ GATCYA+FVGHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQ+I DYYEHRYQG MF+E IL EL+E LRE++I++NCR LVA++P F NAD Sbjct: 176 RLYQAGFMHRQLGAMLQPGVNKFSLRMFGSEKAVEREQERVKSAGFWIIHPYSDFRFYWDLIMLLLMVGNLIIIPVGITFFKDEHTPAWIVFNVVSDTFFLVDLVLNFRTGIVKED-STEIILDPQLIKVRYLRSWFAVDFISSIPVDYIFLIVE-TRIDSDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIISFNCRKLVATMPLFANAD 569 HSP 2 Score: 140.198 bits (352), Expect = 6.439e-161 Identity = 64/105 (60.95%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGD+II+EGTVG +MYFIQ G++ ++TK G T +SDGSYFGEICLL RR ASVRA TYC +YSL + F VLE YP+MRR E+V Sbjct: 572 FVTSMLTKLRFEVFQPGDYIIREGTVGKKMYFIQHGVLTVLTK-GSKETKISDGSYFGEICLLTRGRRTASVRAETYCRLYSLSVDHFNEVLEEYPMMRRAFETV 675
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Match: hcn2b (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [Source:NCBI gene;Acc:103044493]) HSP 1 Score: 448.743 bits (1153), Expect = 5.704e-160 Identity = 236/448 (52.68%), Postives = 312/448 (69.64%), Query Frame = 3 Query: 474 KDNDDGTQSEQSLSEYIGGGAPGYRHPRLS-------------------------ASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 +D D ++ + + AP R PR+S A +++ Q S+ QPG NK ++++FG+Q A+ KE+ R K G+WIIHP S FRFYWD MLM +V NLI++PV I+FF D+ + W++FN VSDT FL+D+ +NFRTGI+ D EIIL+PKQI K Y R+WF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ + +W + Y+++LFKAMSHML IGYGR P S S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQKI DYYEHRYQG MF+E IL+EL+E LRE+++N+NCR LVAS+P F NAD Sbjct: 59 QDMDGASELAPNTTPSTPASAPDRRDPRVSFSTAPGPTKTPEDAQLAGDDGEARDAQTFMQRQFSSMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKDETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYED-NTEIILDPKQIKKKYLRTWFVVDFISSIPVDYIFLIVEKGID-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANAD 504 HSP 2 Score: 137.117 bits (344), Expect = 5.704e-160 Identity = 64/105 (60.95%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQP D+II+EGT+G +MYFIQ G+V ++TK G I LSDGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 507 FVTAMLTKLRFEVFQPLDYIIREGTIGKKMYFIQHGVVSVLTK-GSIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 610
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Match: ENSAMXT00000011919.2 (pep primary_assembly:Astyanax_mexicanus-2.0:10:25443689:25475024:1 gene:ENSAMXG00000011501.2 transcript:ENSAMXT00000011919.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 426.402 bits (1095), Expect = 7.184e-154 Identity = 219/393 (55.73%), Postives = 300/393 (76.34%), Query Frame = 3 Query: 567 SMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHF-SQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 S +++ Q ++ QPG NK ++++FG+ A+ E+ R K G WIIHP S FRFYWDLLML++++ NLI+LPV I+FF D+ + W++FN VSDT+FL+D+ +NFRTGI+ D + EI+L+PK I + Y +SWF++DF+SSIPVDYIFL+++ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP DCW+ K N+ +W QY+++LFKAMSHML IGYG P ++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQKI +YYEHRYQG MF+E +IL ELSE L+E+++++NCR LVA++P F NAD Sbjct: 137 STFIQRQFGAMLQPGVNKFSLRMFGSHKAVALEQERLKSAGVWIIHPYSDFRFYWDLLMLLLMMGNLIILPVGITFFKDENTPPWIIFNVVSDTLFLVDLVLNFRTGIVKED-STEILLDPKAIRQRYLKSWFLVDFVSSIPVDYIFLMVDLEARLDSEVYRTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPIDCWVYKNNMVNDSWGVQYSYALFKAMSHMLCIGYGAQAPEGMTDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADVRQKIHEYYEHRYQGKMFDEENILGELSEPLKEEIVSFNCRSLVANMPLFANAD 528 HSP 2 Score: 138.658 bits (348), Expect = 7.184e-154 Identity = 66/105 (62.86%), Postives = 79/105 (75.24%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ V+ KL +EVFQP DFII+EGTVG +MYFIQ G V ++T+ G T LSDGSYFGEICLL RR ASVRA TYC +YSL +SF VLE +P+MRR E+V Sbjct: 531 FVTAVLTKLRFEVFQPNDFIIREGTVGRKMYFIQHGRVSVLTR-GNKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDSFNEVLEEHPMMRRAFETV 634
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Match: hcn2b (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [Source:NCBI gene;Acc:103044493]) HSP 1 Score: 448.743 bits (1153), Expect = 1.939e-145 Identity = 242/479 (50.52%), Postives = 322/479 (67.22%), Query Frame = 3 Query: 474 KDNDDGTQSEQSLSEYIGGGAPGYRHPRLS-------------------------ASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSFN------REISLSKK 1805 +D D ++ + + AP R PR+S A +++ Q S+ QPG NK ++++FG+Q A+ KE+ R K G+WIIHP S FRFYWD MLM +V NLI++PV I+FF D+ + W++FN VSDT FL+D+ +NFRTGI+ D EIIL+PKQI K Y R+WF++DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ + +W + Y+++LFKAMSHML IGYGR P S S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQKI DYYEHRYQG MF+E IL+EL+E LRE+++N+NCR LVAS+P F NAD L+ + F RE ++ KK Sbjct: 107 QDMDGASELAPNTTPSTPASAPDRRDPRVSFSTAPGPTKTPEDAQLAGDDGEARDAQTFMQRQFSSMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKDETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYEDNT-EIILDPKQIKKKYLRTWFVVDFISSIPVDYIFLIVEKGID-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPLDYIIREGTIGKK 583 HSP 2 Score: 139.428 bits (350), Expect = 8.048e-34 Identity = 64/105 (60.95%), Postives = 80/105 (76.19%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQP D+II+EGT+G +MYFIQ G+V ++TK G I LSDGSYFGEICLL RR ASVRA TYC +YSL ++F VLE YP+MRR E+V Sbjct: 555 FVTAMLTKLRFEVFQPLDYIIREGTIGKKMYFIQHGVVSVLTK-GSIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETV 658
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007865.1 (pep scaffold:Pmarinus_7.0:GL480431:10244:18565:-1 gene:ENSPMAG00000007113.1 transcript:ENSPMAT00000007865.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 262.307 bits (669), Expect = 1.552e-82 Identity = 151/287 (52.61%), Postives = 208/287 (72.47%), Query Frame = 3 Query: 729 WDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEF-FNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWI--------------------VKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYK 1526 WD++ML+++V NLIV+PV I+FF+++ + W+VFN +SDT FL+D+ +NFRTGI++ D D IIL+P+ I Y +SWF++DF+SSIPVDYIFLI+ T S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE ++ AS + I NL+ MMLLL HW+ CLQFL+PM++EFP+DCWI + + +W QY+++LFKAMSHML IGYG+ P S ++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EK + Sbjct: 1 WDIIMLLLMVGNLIVIPVGITFFHEEDTTAWIVFNVLSDTCFLVDLVLNFRTGIVVEDNTD-IILDPQVIKMRYLKSWFLVDFVSSIPVDYIFLIVE-TRIDSEMYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEMTYDLASAVVRIVNLIAMMLLLCHWDGCLQFLVPMLQEFPHDCWISLNGMVVGLAASRTHLRFFAITPVCQNDSWGKQYSYALFKAMSHMLCIGYGQRAPVSMADLWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKMQ 285
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005594.1 (pep scaffold:Pmarinus_7.0:GL476331:707593:738342:1 gene:ENSPMAG00000005049.1 transcript:ENSPMAT00000005594.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 111.694 bits (278), Expect = 1.455e-34 Identity = 105/396 (26.52%), Postives = 181/396 (45.71%), Query Frame = 3 Query: 654 LLKEKSRQKKHGH-WIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKR------------WLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMML---LLGHWNACLQFLIPMMREFPNDC-------WIVKCNLKEANWF------------DQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEID---ILQELSECLREKVINYNCRGLVASVPFFKNA 1727 +L E Q H W I S F+ WD L+L++++ I P +F D + + + D +F++DI +NFRT I + +E++ +P +IA HY + WF+ID +++IP D + F + L LL RLLRL R+ R + ++ E+ G LVL+M L+ HW AC+ + I M E P D W+ + + + D+Y +L+ S + S+G+G P + E +I M+ G+ YA G+ +A+IQ + Y + +V+E++ + ++P LRQ++ +Y++H + + N ID +L+ ECL+ + + R L+ S F A Sbjct: 75 VLPEYKLQAPRIHKWTILHYSPFKAVWDWLILLLVIYTAIFTPYTAAFLLSDQQVENERQKCGYSCNPLNIVDLMVDIMFMVDIFINFRTTYINKN--EEVVSHPGKIAIHYFKGWFLIDMVAAIPFDLLI-----------FGSGSGSGETTTLIGLLKTARLLRLVRVARKLDRYSEY--------GAAVLVLLMCTFALIAHWLACIWYAIGNM-ERPVDSLAKDRIGWLDQLGGQIGKPYNDTDTSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNYEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAW--SYTNGIDMNMVLKGFPECLQADICLHLNRTLLESCKAFNGA 446 HSP 2 Score: 52.7582 bits (125), Expect = 1.455e-34 Identity = 30/83 (36.14%), Postives = 46/83 (55.42%), Query Frame = 2 Query: 1781 PGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEIC--LLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYP 2023 PGD ++ G V + MYF+ G ++I+ +D +A L FGE + A VRA+TYC+++ + RE L VL+ YP Sbjct: 465 PGDTLVHSGDVITAMYFLSRGSIEILREDIVVAI-LGKNDIFGEPVNQYSRPGKSSADVRALTYCDLHKIVREDMLEVLDMYP 546
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Match: kcnh1b (potassium voltage-gated channel, subfamily H (eag-related), member 1b [Source:ZFIN;Acc:ZDB-GENE-121128-4]) HSP 1 Score: 105.145 bits (261), Expect = 8.709e-31 Identity = 110/452 (24.34%), Postives = 192/452 (42.48%), Query Frame = 3 Query: 504 QSLSEYIGGGAPGYRHPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILN--------------NTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLI---PMMREFPN----DCWIVKCN--LKEANWFDQYTW------------SLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSEC---LREKVINYNCRGLVASVPFFKNADDILYR 1745 Q L+ + G ++H RL+ + L I ++ + K H I+H C+ F+ WD ++L++ I++P +SF + WLV + V D IFL+DI +NF T + A E+I +PK I +Y ++WF+ID LS +P D I N + S+ + A + ++ L S L+++RL RL R + + + + + + LV + L HW AC+ + I ++ E N W+ + + F+ W SL+ M+ + SIG+G PT+ E + MM G+ YA G+ + Q + Y E V +++ ++P+ L +++ DY + +M ID + L C +R + + R + P F+ A D R Sbjct: 146 QQLTPNVHKGENVHKHSRLAEVLQLGSDILPQYK--------------------QETPKTPPHIILHYCA-FKTTWDWIILILTFYTAIMVPYNVSFKTKQNNVAWLVVDSVVDVIFLVDIVLNFHTTFV--GPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEVVRAAQIRGPFGSRSPSRLLDAWPRVAPQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVL--LVCVFGLAAHWLACIWYSIGDYEVIDEATNLIRKHSWLYQLGETIGTPYHFNGTQWEGGPSKDAVYISSLYFTMTSLTSIGFGNIAPTTDGEKIFAVAMMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTW--SMSKGIDTEKVLHICPKDMRADICVHLNRKVFNEHPAFRLASDGCLR 570 HSP 2 Score: 46.595 bits (109), Expect = 8.709e-31 Identity = 26/84 (30.95%), Postives = 48/84 (57.14%), Query Frame = 2 Query: 1781 PGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEIC----LLADTRRVASVRAVTYCNVYSLDRESFLSVLEHY 2020 PGD I G + F+ G +++I +D E+ L G FG++ ++A + A+VRA+TYC+++ + R++ + VL+ Y Sbjct: 583 PGDLIYHAGESVDTLCFVVSGSLEVI-QDDEVVAILGKGDVFGDVFWKERVIAPS--CANVRALTYCDLHVIRRDALVKVLDFY 663
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005922.1 (pep scaffold:Pmarinus_7.0:GL476456:333240:381928:-1 gene:ENSPMAG00000005344.1 transcript:ENSPMAT00000005922.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 93.5893 bits (231), Expect = 6.624e-26 Identity = 91/380 (23.95%), Postives = 175/380 (46.05%), Query Frame = 3 Query: 615 NKLAMK--LFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFF----NDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPND------CWIVKCNLKEANWF------------DQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEID---ILQELSECLREKV 1673 NKL + +FG + +L + K + +I+ +F+ WDLL+L+ + +P + F N + V + + +F++DI +NFRT + + +++ + + I HY +WF ID ++++P D ++ + +H K + LLRLLRL + + SQ+ T L+ M LL HW AC+ + I ND W+ + K F Y SL+ A+S + S+G+G + +E ++ +M+ GA +A+ G+ A+IQ + + Y + K +++++ +LP+ L+Q++ +Y++ + N N ID +L++ + LR + Sbjct: 21 NKLKINNNVFGEKPSLPEYKVAAIQKSRFILLHYGTFKAGWDLLILLATFYVAVTVPYNVCFSETVENISDPRSTAVVDISVEILFIIDILLNFRTTYVSK--SGQVVYDGRSICVHYVTTWFFIDLIAALPFDLLYAF---NVSVTTLVHL---------LKTVRLLRLLRLLQNLDRYSQYSTVVLTL--------LMFMFGLLAHWMACIWYKIGRAEIEINDRHSWDIGWLHELGKKLETPFHTNNTGGGPSTRSAYIASLYFALSSLTSVGFGNVSANTDAEKIFSVCAMLIGALMHAVVFGNVTAIIQRMYSRRSQYHTRTKDLKDFIRVHRLPKQLKQRMLEYFQTTWSVN--NGIDTHELLKDFPDELRADI 376 HSP 2 Score: 41.9726 bits (97), Expect = 6.624e-26 Identity = 24/83 (28.92%), Postives = 41/83 (49.40%), Query Frame = 2 Query: 1781 PGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADT--RRVASVRAVTYCNVYSLDRESFLSVLEHYP 2023 PG+F+I++G YF+ G ++++ KD + L G G D + A V+A+TYC++ + VL+ YP Sbjct: 412 PGEFLIRQGDALQAFYFVCSGSMEVL-KDDMVLAILGKGDLIGSDLSSKDQVLKTNADVKALTYCDLQCIHLRGLYDVLDLYP 493
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Match: kcnh8 (potassium voltage-gated channel, subfamily H (eag-related), member 8 [Source:ZFIN;Acc:ZDB-GENE-060503-204]) HSP 1 Score: 101.293 bits (251), Expect = 5.022e-24 Identity = 87/370 (23.51%), Postives = 172/370 (46.49%), Query Frame = 3 Query: 711 SSFRFYWDLLMLMVLVANLIVLPVAISFFNDD----LSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQ-----------------------YTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEID---ILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 +F+ WD L+L+ + +P + F N D S+ +V + S+ +F++DI +NFRT + + +++ N + I HY +WF ID ++++P D + ++ + + F+H + +R+LRL +LL L SQ+ + + L+ M LL HW AC+ ++I D + W + Y SL+ +S + S+G+G + E +I +M+ GA +A+ G+ A+IQ + + LY + + ++E++ +LP L+Q++ +Y++ + N N ID +L++ + LR V + + ++ +P F++A Sbjct: 20 GTFKAGWDWLILLATFYVAVTVPYNVCFLNSDEQCTSSRSTMVSDITSEILFIIDIVLNFRTTYVSG--SGQVVYNGRSICLHYVTTWFPIDLIAALPFDLLVIVRSWGERGTSFVHLLKTVRLLRLLRLLQKLDRY---------SQYSA--------VVLAMLMCMFALLAHWMACIWYIIGFEEMKSTD-----LVTHQIGWLQELQRRLVAPHYPNITQGMPPIRSAYITSLYFTLSSITSVGFGNVSANTDGEKIFSICAMLIGALMHAVVFGNVTAIIQRMYSRRSLYLTRTRDLKEFIRIHRLPHQLKQRMLEYFQTTWSVN--NGIDTNELLKDFPDELRADVTMHLNKEML-QLPLFESAS 362 HSP 2 Score: 27.7202 bits (60), Expect = 5.022e-24 Identity = 12/38 (31.58%), Postives = 22/38 (57.89%), Query Frame = 2 Query: 1781 PGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSD 1894 PG+++I++G YFI G ++ + KDG + L + Sbjct: 380 PGEYLIRQGDALQAFYFILSGSMEAL-KDGTVLAILGE 416
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Yeast
Match: BCY1 (Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA); PKA is a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation [Source:SGD;Acc:S000001295]) HSP 1 Score: 64.6994 bits (156), Expect = 1.712e-11 Identity = 33/93 (35.48%), Postives = 49/93 (52.69%), Query Frame = 2 Query: 1733 YFVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVL 2011 Y +++ L +++QPG+ II+EG G Y I+ G VD+ K + L D YFGE+ LL D R A+V A V +L + F +L Sbjct: 309 YDRAKLADALDTKIYQPGETIIREGDQGENFYLIEYGAVDVSKKGQGVINKLKDHDYFGEVALLNDLPRQATVTATKRTKVATLGKSGFQRLL 401 HSP 2 Score: 57.7658 bits (138), Expect = 3.082e-9 Identity = 30/86 (34.88%), Postives = 49/86 (56.98%), Query Frame = 2 Query: 1784 GDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTM 2041 G IIK+G G Y +++G VD D ++ +S GS FGE+ L+ ++ R A+V A + C +++LDR +F +L +R M Sbjct: 208 GATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNSS-GPGSSFGELALMYNSPRAATVVATSDCLLWALDRLTFRKILLGSSFKKRLM 292
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Match: EDO49064 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI02]) HSP 1 Score: 360.918 bits (925), Expect = 1.260e-130 Identity = 189/372 (50.81%), Postives = 272/372 (73.12%), Query Frame = 3 Query: 612 DNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNA 1727 DNKLA+KLFG ++A++ E+ RQ + G +IHP S+FR+YWD+L+++ + ++++LPV+I+F +DDLS WL+ NGVSD F++DI +NFRTGI+ + +E+IL+ K I+ Y R WFIID SS+P DY + I ++T + A RALRIL+LAKLLSLLRLLR+SRLVRY++++EE N A + I L+ ML+L HWN C+QF +P ++EFP+D W+ NLK A+ +QY+WSLF+A+SHML IGYG +PP + ++ W+T+ SM GAT YA+F+G ++LI S D+S RL+ EK QVEEYM YRKLP +R ++ D+YEHR+ +F+E IL ELS+ LRE ++ +N + L+ +VPFF A Sbjct: 1 DNKLALKLFGNKAAVMLEQRRQSQQGKGVIHPFSTFRWYWDILLIIFIFMHVLLLPVSIAFLSDDLSIHWLILNGVSDVFFVVDIFLNFRTGIVDPNNQEEVILDKKVISMMYLRGWFIIDLASSLPFDYAYFIASSTTEEQTLLRASRALRILKLAKLLSLLRLLRVSRLVRYMTRFEELLNIAKGQLRIMKLICCMLVLSHWNGCIQFFVPYLQEFPDDSWVSTSNLKTASPGEQYSWSLFRALSHMLCIGYGHYPPQNLTDLWLTVCSMTAGATFYAVFIGIMSSLIMSIDSSGRLFNEKLNQVEEYMRYRKLPLRIRLQVQDFYEHRFHHKLFDEDAILTELSKNLRETILVHNIKPLLTTVPFFSGA 372 HSP 2 Score: 125.176 bits (313), Expect = 1.260e-130 Identity = 60/106 (56.60%), Postives = 79/106 (74.53%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLA-DTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 F++++V KL +EVF GD+I + G G +MYFIQ+GIVDI+T++G +ATSL DGS+FGEICLL + RRVASVRA T C+VYSL F VL+ YP M+ +E V Sbjct: 376 FITDIVTKLKFEVFLNGDYICRSGHRGDKMYFIQKGIVDILTREGALATSLGDGSHFGEICLLTKEARRVASVRAATTCDVYSLSATHFHEVLQDYPEMKSVLEEV 481
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Match: EDO34316 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPS0]) HSP 1 Score: 376.711 bits (966), Expect = 3.873e-130 Identity = 203/385 (52.73%), Postives = 277/385 (71.95%), Query Frame = 3 Query: 576 LKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 ++ ++ S +P DNK+ MK+FG++ A+ E+ R + G W+IHP S FR YWD+ +L++L+ NL LPV ISFF D++S RW+ FN VSDT FLLDI +NFRTG++++ ++ IL+PK IAK Y ++WF ID +SS+P+DYI ++ S + A R L++LR AKLL LL+LLRLSRLVRY+ Q+EE N I NLV ++LL+ HWN CLQFL+P +++FP W+ NL + +W++QY WSLFKAMSHML IGYGR+PP + +E WVT SM+TGAT YA+F+ + IQ D+ R YREK +Q+EEYM YR+LP LR ++T YY+HRYQG MF+E IL E+S+ LRE++INYNCR LV SVPFF A+ Sbjct: 1 IEMRLKSWLKPMDNKMNMKVFGSKRAMKDEQLRYSRAG-WVIHPTSIFRLYWDMWVLLLLLINLFALPVLISFFADNVSARWIAFNAVSDTAFLLDILLNFRTGVLVHGSPNKFILDPKIIAKRYLKTWFFIDLISSLPIDYIVEAATQSSTKS-LIGATRTLKLLRFAKLLGLLKLLRLSRLVRYVQQYEEILNVTRSVIRFINLVSIILLIAHWNGCLQFLVPYLQDFPETSWVSIHNLMDNDWWEQYCWSLFKAMSHMLCIGYGRYPPQNIAEVWVTTFSMLTGATFYAMFIAYCINFIQQLDSPGRNYREKIQQIEEYMSYRRLPVELRDRMTKYYDHRYQGRMFDEEKILHEISKPLREQIINYNCRDLVQSVPFFTEAE 383 HSP 2 Score: 107.842 bits (268), Expect = 3.873e-130 Identity = 51/105 (48.57%), Postives = 74/105 (70.48%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVS ++ +L +EV+ GD I++EG +G++MYF++EG+V + T G+ A L DG+YFGEICLL + RR ASV A T C+V+ L+ E F V++ +P MR ME V Sbjct: 386 FVSAIITRLSFEVYLEGDIIVREGELGTEMYFLREGVVSV-TVGGKHANELCDGAYFGEICLLTNARRTASVTAKTVCDVFILNAEHFRDVVDEFPTMRILMEIV 489
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Match: EDO35393 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLM8]) HSP 1 Score: 84.7297 bits (208), Expect = 1.463e-35 Identity = 42/119 (35.29%), Postives = 73/119 (61.34%), Query Frame = 2 Query: 1709 SIL*KCR*YFVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDG-EIATSLSDGSYFGEICLL----ADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 +I C F+ E+V++L ++F PGD++ ++G VG +MY + G ++++++ G +I L GSYFGEI +L A RR ASVR+V Y ++ L + + VL+ YP ++ +E + Sbjct: 321 AIFQDCEAGFLCELVLRLRSQLFSPGDYVCRKGEVGREMYIVNRGKLEVVSEHGTKIYAVLEAGSYFGEISVLSMSSAGNRRTASVRSVGYTELFCLAKNDLMEVLDEYPNIKEKIEKI 439 HSP 2 Score: 83.9593 bits (206), Expect = 1.463e-35 Identity = 78/337 (23.15%), Postives = 154/337 (45.70%), Query Frame = 3 Query: 723 FYWDLLMLMVLVANL--IVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILN--PKQIAKHYARSW-FIIDFLSSIPVD--YIFL------ILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVK------CNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMF-NEIDILQELSECLREKV 1673 ++W L++ + ++ N I+L A ND ++ WL+ + D I++ DI V+ RTG F +E IL ++ +HY ++ F +D + IP+D YIF+ +N F +F H ++ + E T + + +LV +LL+ HWNAC+ F++ F +D W+ N E Y +S + + + +IG PP S E + + + G +A VG+ +I + + ++ ++ K ++ YM + K+P+ L++++ ++++ + +E +IL L + LR ++ Sbjct: 6 YFWLLVVSLAVLYNCWAIILRTAFPQINDKITYIWLILDYSCDLIYIADILVSMRTG-----FLEEGILQTCSTKMRRHYLHTYEFYLDAGALIPLDIAYIFIEHEPAFRINRILKFHRFWH---------------------------FLDRTESR-TTFPNVVRLASLVQFILLIIHWNACIYFIVSREIGFGSDVWVYPGVRQEILNSSENTISRMYIYSFYWSTLTLTTIGEVP-PPYSEVEYIIVTLDYLIGVLLFATIVGNVGNIITNLNATRLDFQNKMDGIKAYMRFHKIPQHLQRRVIKWFDYLWTYKKHPDEEEILLSLPDKLRAEI 308
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Match: EDO30140 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1M9]) HSP 1 Score: 115.546 bits (288), Expect = 1.251e-34 Identity = 103/376 (27.39%), Postives = 182/376 (48.40%), Query Frame = 3 Query: 654 LLKEKSRQKKHGH-WIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFF------NDDLSKR------------------WLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMML---LLGHWNACLQFLIP-MMREFPNDC--WIVKCNLKEANWFDQ------------YTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELS 1652 +L E Q + H W I S F+ +WD L+L +++ IV P SF D+L+K ++ + + D +F++DI +NFRT + D DE++ +P +IA HY ++WF+ID +++IP + + +++ NT+ + + LL RLLRL R+ R + + E+ G+ L L+M LL HW AC+ + I + R+ N W+ + FD+ Y +L+ +S + S+G+G P + +E +I M+ G+ YA G+ AA+I ++ Y + ++V E++ + ++P LRQ+I DY H + + N ID+ Q+L+ Sbjct: 194 VLPEYKLQAPNIHPWTILHYSVFKAFWDWLILFLVIYTAIVTPYMASFILTRDKMRDELNKDPETRRDYGSGAREVYSDPLVILDYLVDVMFIVDIFINFRTTFV--DSNDEVVSHPCRIAVHYFKTWFVIDLMAAIPFE-LLIMVGNTDETTTLI------------GLLKTARLLRLVRVARKLDHYSEY--------GMAVLCLLMCSFALLAHWLACIWYAIGNLERQRTNSTHGWLDVLAEQIHRPFDEKEVDSGPDIESKYITALYFTLSSLTSVGFGNVSPNTNAEKIFSICVMLIGSLFYAAIFGNVAAIIARLYSNTARYHAQMQRVREFIRFHQIPNPLRQRIEDYSHHIW--SYTNGIDMDQDLN 544 HSP 2 Score: 50.0618 bits (118), Expect = 1.251e-34 Identity = 34/122 (27.87%), Postives = 56/122 (45.90%), Query Frame = 2 Query: 1748 VVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSD-------------------GSYFGEICLLADTRRVA----SVRAVTYCNVYSLDRESFLSVLEHYPIMRRTME 2044 + +KL PGDFII +G S +YF+ G V+++ KD I L + G FGE L+ R S+RA+TYC++ ++ R+ ++ + YP ++T Sbjct: 565 LALKLRTTHLPPGDFIIYQGDEISHLYFLVRGTVEVL-KDDTIMAILGEQEDEIMMLCLQFSIYLQGKGDSFGENFGLSPNRPPGNSHVSIRALTYCDLRAISRDDLVNTMRMYPNFQQTFN 685
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Match: EDO35376 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLM9]) HSP 1 Score: 85.8853 bits (211), Expect = 1.292e-33 Identity = 80/358 (22.35%), Postives = 164/358 (45.81%), Query Frame = 3 Query: 696 IIHPCSSFRFYWDLLMLMVLVANLIVLPVAISF--FNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSW-FIIDFLSSIPVDYIFLILNNTN--HFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWI-VKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVT----IVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEH--RYQGNMFNEIDILQELSECLREKV-INYNCRGLVASVPFFKNAD 1730 ++ P +F F W L + + ++ N L V ++F ++ K + + D+IF LD V FR G + + +++ ++ K Y S+ F++D +S +P D ++L L F++ A E ++ K + L+ + L+ HW AC+ F++ F D W+ + + + + QY +SL+++ M ++G G +T +T IV+ +TG +A VG+A +I S+ Y K ++EY+ +LP L++++ ++++ R++ +M NE ++ +L++ + ++ I+ N L+ V F + D Sbjct: 2 VLDPSGTFYFLWLLTVSLGVIYNYWALIVYVAFPSVHEANLKTCIAVDYTFDSIFFLDTLVQFRVGFLEHGV---MVVGCWKLTKKYGCSFGFMLDLISILPFDVLYLYLGVLPILRFNRLFKA----------------------HRFLLFCDRGEIYSGRPKLFNLAKLIHYLFLIIHWVACVYFILSRYEGFGTDEWLHPRLDGQLSKLSMQYLYSLYRSSVSMTTVGAGVIGTIATPRTELTLCFVIVTYLTGVLIFATIVGNAGDMIVEMRRSRERYLRKLNGMKEYIEAYQLPAHLKKRVIHWFDYLWRHKRDM-NEQELFHKLNDNFKAEIAIHVNLDTLI-RVEMFHDCD 332 HSP 2 Score: 76.2554 bits (186), Expect = 1.292e-33 Identity = 39/107 (36.45%), Postives = 63/107 (58.88%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLA----DTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTME 2044 F+ E+V+KL + PGDFI ++G G +MY + +G ++++ + + +LS GS+FGEI LL R ASVR+V + +++ L + VLE YP + ME Sbjct: 335 FLHELVLKLRPVICSPGDFICRQGEKGREMYIVNKGSLEVLDEKETVLATLSAGSHFGEISLLNMKGIGNLRTASVRSVGFSDLFQLSKTDLEEVLEFYPQAKEQME 441
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Match: ENSORLT00000019258.2 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [Source:NCBI gene;Acc:101172279]) HSP 1 Score: 445.277 bits (1144), Expect = 1.151e-159 Identity = 226/396 (57.07%), Postives = 300/396 (75.76%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 R S + +++ Q S+ QPG NK +++++G+Q A+ +E+ R K G+WIIHP S FRFYWD ML+ +V NLI++PV I+FF D+ + W++FN VSDT FL+D+ +NFRTGII+ D +D IIL+PK I Y ++WFI+DF+SSIPVDYIFLI+ S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + IFNL+ MMLLL HW+ CLQFL+PM++EFP+DCW+ ++ W + Y++++FKAMSHML IGYGR P S S+ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP RQKI DYYEHRYQG MF+E IL ELSE LRE+++N+NCR LVAS+P F NA+ Sbjct: 328 RGSQASFMQRQFSSMLQPGVNKFSLRMYGSQKAVEREQERVKSAGNWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTTPWIIFNVVSDTFFLMDLVLNFRTGIIIEDNSD-IILDPKTIKTKYLKTWFIVDFISSIPVDYIFLIVEKGID-SEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRIFNLIGMMLLLCHWDGCLQFLVPMLQEFPSDCWVSLNKMENDTWSELYSFAVFKAMSHMLCIGYGRQAPESLSDIWLTMLSMIVGATCYAVFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILGELSEPLREEIVNFNCRKLVASMPLFANAE 721 HSP 2 Score: 139.428 bits (350), Expect = 1.151e-159 Identity = 64/105 (60.95%), Postives = 79/105 (75.24%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQP D+II+EGT+G +MYFIQ G+ +ITK G +A LSDGSYFGEICLL RR ASVRA TYC +YSL + F VLE YP+MRR E+V Sbjct: 724 FVTAMLTKLRFEVFQPHDYIIREGTIGKKMYFIQHGVCSVITK-GTLAMKLSDGSYFGEICLLTRGRRTASVRAETYCRLYSLSVDHFNEVLEEYPMMRRAFETV 827
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Match: ENSORLT00000045599.1 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 [Source:NCBI gene;Acc:101158796]) HSP 1 Score: 434.876 bits (1117), Expect = 2.199e-156 Identity = 216/392 (55.10%), Postives = 302/392 (77.04%), Query Frame = 3 Query: 567 SMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 S +++ Q ++ QPG NK ++++FG+ A+ E+ R K G WIIHP S FRFYWDLLML++++ NLIVLPV I+FF D+ + W++FN VSDT+F++D+ +NFRTGI+ D EI+L+P++I ++Y +SWF++DF+SSIPVDYIFL++++ + S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ K + W QY+++LFKAMSHML IGYG P ++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQKI +YYEHR+QG MF+E +IL ELSE L+E+++++NCR LVA++P F NAD Sbjct: 182 STFIQRQFGAMLQPGVNKFSLRMFGSHKAVAMEQERLKSAGAWIIHPYSDFRFYWDLLMLILMMGNLIVLPVGITFFRDENTASWIIFNVVSDTLFMVDLVLNFRTGIVKED-NTEILLDPREIRQNYLKSWFLVDFVSSIPVDYIFLMMDSLD--SEVYRTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSKNLMVNDTWGVQYSYALFKAMSHMLCIGYGAQAPEGMTDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHEYYEHRFQGKMFDEENILGELSEPLKEEIVSFNCRSLVANMPLFANAD 570 HSP 2 Score: 139.043 bits (349), Expect = 2.199e-156 Identity = 66/105 (62.86%), Postives = 79/105 (75.24%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ V+ KL +EVFQP DFII+EGTVG +MYFIQ G V ++T+ G T LSDGSYFGEICLL RR ASVRA TYC +YSL +SF VLE +P+MRR E+V Sbjct: 573 FVTAVLTKLRFEVFQPADFIIREGTVGRKMYFIQHGRVSVLTR-GNKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDSFNEVLEEHPMMRRAFETV 676
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Match: ENSORLT00000013376.2 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 [Source:NCBI gene;Acc:101158796]) HSP 1 Score: 434.106 bits (1115), Expect = 3.280e-156 Identity = 216/392 (55.10%), Postives = 302/392 (77.04%), Query Frame = 3 Query: 567 SMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 S +++ Q ++ QPG NK ++++FG+ A+ E+ R K G WIIHP S FRFYWDLLML++++ NLIVLPV I+FF D+ + W++FN VSDT+F++D+ +NFRTGI+ D EI+L+P++I ++Y +SWF++DF+SSIPVDYIFL++++ + S+ RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP+DCW+ K + W QY+++LFKAMSHML IGYG P ++ W+T++SM+ GATCYA+F+GHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQKI +YYEHR+QG MF+E +IL ELSE L+E+++++NCR LVA++P F NAD Sbjct: 49 STFIQRQFGAMLQPGVNKFSLRMFGSHKAVAMEQERLKSAGAWIIHPYSDFRFYWDLLMLILMMGNLIVLPVGITFFRDENTASWIIFNVVSDTLFMVDLVLNFRTGIVKED-NTEILLDPREIRQNYLKSWFLVDFVSSIPVDYIFLMMDSLD--SEVYRTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSKNLMVNDTWGVQYSYALFKAMSHMLCIGYGAQAPEGMTDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHEYYEHRFQGKMFDEENILGELSEPLKEEIVSFNCRSLVANMPLFANAD 437 HSP 2 Score: 139.043 bits (349), Expect = 3.280e-156 Identity = 66/105 (62.86%), Postives = 79/105 (75.24%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ V+ KL +EVFQP DFII+EGTVG +MYFIQ G V ++T+ G T LSDGSYFGEICLL RR ASVRA TYC +YSL +SF VLE +P+MRR E+V Sbjct: 440 FVTAVLTKLRFEVFQPADFIIREGTVGRKMYFIQHGRVSVLTR-GNKETKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDSFNEVLEEHPMMRRAFETV 543
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Match: ENSORLT00000019259.2 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 [Source:NCBI gene;Acc:101159259]) HSP 1 Score: 428.713 bits (1101), Expect = 1.269e-153 Identity = 224/396 (56.57%), Postives = 299/396 (75.51%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 RL + ++ Q ++ QPG NK ++++ G++ A+ E+ R K G WIIHP S FRFYWDL ML+++V NL+++PV I+FF D+ + W+VFN VSDT FL+D+ +NFRTGI+ D EIIL+P++I Y +SWF++DF+SSIPVDYIFLI+ T S F RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CLQFL+PM+++FP DCW+ + + W QY+++LFKAMSHML IGYG +PP ++ W+TI+SM+ GATC+A+FVGHA ALIQS D+S+R Y+EKYKQVE+YM + KLP +RQ+I DYYEHRYQG MF+E +IL+EL+E LRE++IN+NCR LVAS+P F NAD Sbjct: 165 RLYQAGFMHRQFGAMLQPGVNKFSLRMLGSERAVEHERERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLVIIPVGITFFKDEHTPPWIVFNVVSDTFFLMDLVLNFRTGIVKED-NTEIILDPQKIKIKYLKSWFMVDFISSIPVDYIFLIVE-TRIDSDFYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEVFHMTYDLASAMVRIMNLIAMMLLLCHWDGCLQFLVPMLQDFPADCWVTRNKMVNDTWGQQYSYALFKAMSHMLCIGYGLYPPIGMADVWLTILSMIVGATCFAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEENILEELNEPLREEIINFNCRKLVASMPLFANAD 558 HSP 2 Score: 135.961 bits (341), Expect = 1.269e-153 Identity = 63/105 (60.00%), Postives = 78/105 (74.29%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FV+ ++ KL +EVFQPGDFII+EGT G +MYFIQ G+V +IT + T L+DGSYFGEICLL RR ASVRA YC +YSL ++F VLE YP+MRR E+V Sbjct: 561 FVTSMLTKLRFEVFQPGDFIIREGTNGKKMYFIQHGVVSVITNHSK-DTKLTDGSYFGEICLLTRGRRTASVRADNYCRLYSLSVDNFDEVLEEYPMMRRAFETV 664
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Match: hcn3 (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like [Source:NCBI gene;Acc:101157708]) HSP 1 Score: 421.394 bits (1082), Expect = 6.708e-150 Identity = 214/392 (54.59%), Postives = 292/392 (74.49%), Query Frame = 3 Query: 573 YLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLI--LNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFF----NTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 Y ++Q+ SL QPG NK ++++FG+ + E+ R K G WIIHP S FRFYWD++ML+++++NL++LP I+FF D + W+VFN +SDT+FL+D+ NFRTGI++ D +IL+PK+I HY ++WF++DF+SSIPVDYIFL+ L + S RALRI+R K+LSLLRLLRLSRL+RYI QWEE F + AS + I NL+ MMLLL HW+ CL F++PM+++FP DCW+ + N+ A W QY+++LF AMSHML IGYG PP S+ W+T+VSM+ GATCYA+F+GHAA L+QS D S R Y+EKYKQVE+YM + KLP +RQ+I DYYEHR+QG MF+E IL ELS+ L+E++++YNCRGLVA++P F N D Sbjct: 106 YFQKQLGSLLQPGINKFSLRMFGSHKGVAAEQERVKSFGVWIIHPYSDFRFYWDIVMLLLMMSNLVILPWGITFFEDQNTLPWIVFNVLSDTLFLMDLIFNFRTGILVED--SHVILDPKEIRMHYIQTWFLVDFVSSIPVDYIFLVVDLEGRHESSDVYRTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLTFMVPMLQDFPPDCWVYRNNMVNATWHIQYSYALFMAMSHMLCIGYGANPPEGMSDVWLTMVSMVVGATCYAMFLGHAANLVQSLDASHRQYQEKYKQVEQYMSFHKLPADVRQRIHDYYEHRFQGKMFDEDSILGELSDPLKEEIVSYNCRGLVANMPLFANTD 495 HSP 2 Score: 130.568 bits (327), Expect = 6.708e-150 Identity = 62/106 (58.49%), Postives = 78/106 (73.58%), Query Frame = 2 Query: 1733 YFVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 +FV+ ++ KL +EVFQPGDFII+EGT+G +MYFIQ G V +I + G LSDG+YFGEICLL RR ASV+A TYC +YSL + F VLE +P+MRR ESV Sbjct: 497 HFVTVILTKLRFEVFQPGDFIIREGTLGRKMYFIQHGTVMVIPR-GSKEIRLSDGAYFGEICLLTQGRRTASVKAETYCRLYSLSADDFNEVLEEHPLMRRAFESV 601
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Match: SMESG000020049.1 (SMESG000020049.1) HSP 1 Score: 606.29 bits (1562), Expect = 0.000e+0 Identity = 309/392 (78.83%), Postives = 352/392 (89.80%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 R + S YLKEQ S FQP DNKLAMKLFG ++AL KEK RQ++ G W+IHPCS+FRFYWDLLML +L+ANLI+LPVAISFFNDDLS +W++FN +SDTIFLLDI VNFRTG+I ND+ADEIIL PKQIA++Y +SWF +DF+SSIP+DYIFLILN +F+Q MHAGRALRILRLAKLLSLLRLLRLSRLVRY+SQWEE N ASKFIGIFNLVL+MLLLGHWNACLQFLIPM+R++P+D W++KC LKEA WFDQYTW+LFKAMSHMLSIGYGR+PPTS EAW+TIVSMMTGATCYALFVGHAAALIQS+DTSKRLYREK+KQVEEYM YRKLPR LRQ+I +YYEHRYQG MFNE+DIL ELSECLRE++INYNCR LVA+VPFF AD Sbjct: 248 RQTTSSYLKEQFLSFFQPSDNKLAMKLFGNKNALNKEKRRQQQQGKWVIHPCSNFRFYWDLLMLSLLIANLIILPVAISFFNDDLSLKWIIFNCISDTIFLLDIFVNFRTGVITNDYADEIILVPKQIAQNYLKSWFALDFISSIPLDYIFLILNKKEYFNQIMHAGRALRILRLAKLLSLLRLLRLSRLVRYVSQWEELLNVASKFIGIFNLVLLMLLLGHWNACLQFLIPMLRDYPSDSWVIKCKLKEAYWFDQYTWALFKAMSHMLSIGYGRYPPTSICEAWITIVSMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRGLRQRIANYYEHRYQGKMFNELDILNELSECLREQIINYNCRALVAAVPFFTYAD 639 HSP 2 Score: 192.2 bits (487), Expect = 0.000e+0 Identity = 90/105 (85.71%), Postives = 99/105 (94.29%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVSEVVVKL YEVFQPGD IIKEG +G++MYFIQEGIVDIITK+GE+ATSLSDGSYFGEICLL + RRVASVRA TYCNVYSLDR+SFLSVLE+YP+MRRTMESV Sbjct: 642 FVSEVVVKLQYEVFQPGDLIIKEGNLGTRMYFIQEGIVDIITKEGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNVYSLDRDSFLSVLENYPLMRRTMESV 746
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Match: SMESG000038954.1 (SMESG000038954.1) HSP 1 Score: 583.178 bits (1502), Expect = 0.000e+0 Identity = 312/464 (67.24%), Postives = 370/464 (79.74%), Query Frame = 3 Query: 351 KKPKASANDLNQSFNLLNVKNFDSAFHMFNPLDSFRVNKTPKDNDDGTQSEQSLSEYIGGGAPGYRHPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNN----TNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 +K S ++++ SF +K A F +D R +++ +NDD T G + + AS YLKEQ S FQP DNKLA+KLFG ++A+ KE+ RQ++ G +IHPCS+FRFYWDL+ML++L+ NLIVLPVAISFFNDDLS W+VFN VSDTIF+LDI VNFRTGII NDFADEIIL+PK IA+ Y +SWFI+D LSSIP+DY+FL+LN+ ++SQF HAGR LRI RLAKLLS+LRLLRLSRLVRY+SQWEEF N ASKFIGI LVL+MLLLGHWNACLQFLIPM+ E+P + W++KCNLK+A WF QYTW+LFKAMSHMLSIGYGRFPPTS SEAW+TIVSMMTGATCYALFVGHAAA+IQS+DTSKRLYREK+KQVEEYM YRKLPR LRQ+I +YYEHRYQG MF+E IL ELSECLRE++INYNCR LVA+VPFF AD Sbjct: 217 EKTAHSLSNIDSSFEKDIIKRSHEADGQFEDVDE-RSDESNDENDDQTN--------------GDLNNKSRASSYLKEQFFSFFQPSDNKLALKLFGNKNAVNKERRRQQQQGKLVIHPCSNFRFYWDLMMLVLLITNLIVLPVAISFFNDDLSLHWIVFNCVSDTIFILDIAVNFRTGIITNDFADEIILDPKIIARRYVKSWFILDLLSSIPMDYLFLVLNHGPDKNENYSQFFHAGRTLRIFRLAKLLSMLRLLRLSRLVRYVSQWEEFLNMASKFIGICKLVLLMLLLGHWNACLQFLIPMLMEYPAESWVIKCNLKDAYWFKQYTWALFKAMSHMLSIGYGRFPPTSISEAWITIVSMMTGATCYALFVGHAAAIIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEEVILIELSECLREQIINYNCRALVAAVPFFTYAD 665 HSP 2 Score: 181.03 bits (458), Expect = 0.000e+0 Identity = 83/105 (79.05%), Postives = 96/105 (91.43%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVSEVV KL +EV+QPGD IIKEGT+G++M+FIQEGIVDIITKDGE+ATSLSDGSYFGEICLL + +RVASVRA TYCN+YSLD E F +VLE+YP+MRRTMESV Sbjct: 668 FVSEVVTKLKFEVYQPGDLIIKEGTIGTKMFFIQEGIVDIITKDGEVATSLSDGSYFGEICLLTNAKRVASVRAETYCNLYSLDAEHFQAVLENYPLMRRTMESV 772
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Match: SMESG000038954.1 (SMESG000038954.1) HSP 1 Score: 572.392 bits (1474), Expect = 0.000e+0 Identity = 312/481 (64.86%), Postives = 370/481 (76.92%), Query Frame = 3 Query: 351 KKPKASANDLNQSFNLLNVKNFDSAFHMFNPLDSFRVNKTPKDNDDGTQSEQSLSEYIGGGAPGYRHPRLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNN----TNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEE-----------------FFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 +K S ++++ SF +K A F +D R +++ +NDD T G + + AS YLKEQ S FQP DNKLA+KLFG ++A+ KE+ RQ++ G +IHPCS+FRFYWDL+ML++L+ NLIVLPVAISFFNDDLS W+VFN VSDTIF+LDI VNFRTGII NDFADEIIL+PK IA+ Y +SWFI+D LSSIP+DY+FL+LN+ ++SQF HAGR LRI RLAKLLS+LRLLRLSRLVRY+SQWEE F N ASKFIGI LVL+MLLLGHWNACLQFLIPM+ E+P + W++KCNLK+A WF QYTW+LFKAMSHMLSIGYGRFPPTS SEAW+TIVSMMTGATCYALFVGHAAA+IQS+DTSKRLYREK+KQVEEYM YRKLPR LRQ+I +YYEHRYQG MF+E IL ELSECLRE++INYNCR LVA+VPFF AD Sbjct: 280 EKTAHSLSNIDSSFEKDIIKRSHEADGQFEDVDE-RSDESNDENDDQTN--------------GDLNNKSRASSYLKEQFFSFFQPSDNKLALKLFGNKNAVNKERRRQQQQGKLVIHPCSNFRFYWDLMMLVLLITNLIVLPVAISFFNDDLSLHWIVFNCVSDTIFILDIAVNFRTGIITNDFADEIILDPKIIARRYVKSWFILDLLSSIPMDYLFLVLNHGPDKNENYSQFFHAGRTLRIFRLAKLLSMLRLLRLSRLVRYVSQWEEKYLISTCDQGYLTFPQKFLNMASKFIGICKLVLLMLLLGHWNACLQFLIPMLMEYPAESWVIKCNLKDAYWFKQYTWALFKAMSHMLSIGYGRFPPTSISEAWITIVSMMTGATCYALFVGHAAAIIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIANYYEHRYQGKMFDEEVILIELSECLREQIINYNCRALVAAVPFFTYAD 745 HSP 2 Score: 181.03 bits (458), Expect = 0.000e+0 Identity = 83/105 (79.05%), Postives = 96/105 (91.43%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVSEVV KL +EV+QPGD IIKEGT+G++M+FIQEGIVDIITKDGE+ATSLSDGSYFGEICLL + +RVASVRA TYCN+YSLD E F +VLE+YP+MRRTMESV Sbjct: 748 FVSEVVTKLKFEVYQPGDLIIKEGTIGTKMFFIQEGIVDIITKDGEVATSLSDGSYFGEICLLTNAKRVASVRAETYCNLYSLDAEHFQAVLENYPLMRRTMESV 852
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Match: SMESG000038402.1 (SMESG000038402.1) HSP 1 Score: 565.459 bits (1456), Expect = 0.000e+0 Identity = 287/408 (70.34%), Postives = 343/408 (84.07%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNADDILYRK*LSNFIMKSF 1778 + S S YLKEQ S FQP DNKLA+KLFG+++A+++EK RQ+K WIIHPCSSFRFYWDL ML++L+ANLI+LPV +SFF D + +W++FN SDT+FL DI VNFRTGI+L D +DEIILNPK IA++Y RSWF +D +SSIP+DYIFL +N ++ F++AG+ LRILRLAKLLS+LRLLRLSRLVRY+SQWEEF N ASKFIGI LVL+MLLLGHWNAC+QFLIP++ EFP + W+VKC L+ + WF+QYTWSLFKAMSHMLSIGYGRFPPTS SEAW+TI+SMMTGATCYALFVGHAAALIQS+DTSKRLYREK+KQVEEYM YRKLPR LRQ+I +YYEHRYQG MFNE IL EL+ECLRE+VINYNCR LVA+VPFF AD + +S + + F Sbjct: 170 KQSTSSYLKEQFLSFFQPSDNKLALKLFGSKNAVIQEKKRQQKEAKWIIHPCSSFRFYWDLFMLVMLIANLIILPVIVSFFTDSMRIQWVIFNCFSDTVFLADIAVNFRTGILLTDKSDEIILNPKIIARNYLRSWFFLDLISSIPLDYIFLAVNRGENYHHFVYAGKTLRILRLAKLLSMLRLLRLSRLVRYVSQWEEFLNIASKFIGICKLVLLMLLLGHWNACIQFLIPVLMEFPTESWVVKCKLQHSYWFEQYTWSLFKAMSHMLSIGYGRFPPTSISEAWITIISMMTGATCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMTYRKLPRALRQRIANYYEHRYQGKMFNEDQILTELNECLREQVINYNCRALVAAVPFFTYADQSFVSEVVSKLMYEVF 577 HSP 2 Score: 176.407 bits (446), Expect = 3.619e-46 Identity = 81/105 (77.14%), Postives = 93/105 (88.57%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVSEVV KL YEVFQPGD IIKEGT+G++MYFIQEGIVDIITKDGE+ TSLSDGSYFGEICLL + +R A+VRA YC++YSLD E F +VLE+YP+MRRTMESV Sbjct: 564 FVSEVVSKLMYEVFQPGDLIIKEGTIGTKMYFIQEGIVDIITKDGEVVTSLSDGSYFGEICLLTNAKRCATVRAEVYCSLYSLDSEQFKAVLENYPLMRRTMESV 668
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Match: SMESG000001696.1 (SMESG000001696.1) HSP 1 Score: 561.992 bits (1447), Expect = 0.000e+0 Identity = 290/392 (73.98%), Postives = 337/392 (85.97%), Query Frame = 3 Query: 555 RLSASMYLKEQICSLFQPGDNKLAMKLFGTQSALLKEKSRQKKHGHWIIHPCSSFRFYWDLLMLMVLVANLIVLPVAISFFNDDLSKRWLVFNGVSDTIFLLDIGVNFRTGIILNDFADEIILNPKQIAKHYARSWFIIDFLSSIPVDYIFLILNNTNHFSQFMHAGXXXXXXXXXXXXXXXXXXXXXXXXXYISQWEEFFNTASKFIGIFNLVLMMLLLGHWNACLQFLIPMMREFPNDCWIVKCNLKEANWFDQYTWSLFKAMSHMLSIGYGRFPPTSTSEAWVTIVSMMTGATCYALFVGHAAALIQSYDTSKRLYREKYKQVEEYMGYRKLPRLLRQKITDYYEHRYQGNMFNEIDILQELSECLREKVINYNCRGLVASVPFFKNAD 1730 +LS + YLKEQ S FQP DNKLAMKLFG ++AL KEK RQ++ G WIIHPCS+FRFYWDL+ML++L+ANLI+LPVAISFFNDDLS W+VFN SDTIFLLDI VNFR+GII ++FADEIIL+P QI K+Y SWF +D +SSIP+DYIFLI+N + +SQF+HAGR LRIL+LAKLLS+LRLLRLSRLVRY+SQWEEF N A+KF+GI LVLMMLLL HWNACLQ+LIP++ +FP D W+ KC L+ A WF QYTW+LFKA+SHMLSIGYGRFPPTS SEAW+T+ S++ G TCYALFVGHAAALIQS+DTSKRLYREK+KQVEEYM YRKLPR LRQ+I YYEHRYQG MFNE IL ELSECLRE++INYNCR LVASVPFF AD Sbjct: 196 KLSTTGYLKEQFFSFFQPADNKLAMKLFGNKNALNKEKRRQQQAGKWIIHPCSNFRFYWDLMMLILLIANLIILPVAISFFNDDLSLHWIVFNCASDTIFLLDIMVNFRSGIIADNFADEIILDPNQICKNYIHSWFFLDLISSIPMDYIFLIINRKDVYSQFVHAGRGLRILKLAKLLSILRLLRLSRLVRYVSQWEEFLNMANKFMGICKLVLMMLLLAHWNACLQYLIPVLNDFPADSWVTKCKLQHAYWFHQYTWALFKALSHMLSIGYGRFPPTSISEAWITVTSVLIGVTCYALFVGHAAALIQSFDTSKRLYREKFKQVEEYMAYRKLPRALRQRIDSYYEHRYQGKMFNEDLILSELSECLREQIINYNCRALVASVPFFTYAD 587 HSP 2 Score: 183.726 bits (465), Expect = 0.000e+0 Identity = 86/105 (81.90%), Postives = 95/105 (90.48%), Query Frame = 2 Query: 1736 FVSEVVVKLHYEVFQPGDFIIKEGTVGSQMYFIQEGIVDIITKDGEIATSLSDGSYFGEICLLADTRRVASVRAVTYCNVYSLDRESFLSVLEHYPIMRRTMESV 2050 FVSEVV KL +EVFQPGD IIKEGTVG++MYFIQEGIVDIITKDGE+ATSLSDGSYFGEICLL + +RVASVRA TYCN+YSLD FL VLE+YP+MRRTMESV Sbjct: 590 FVSEVVTKLKFEVFQPGDLIIKEGTVGTKMYFIQEGIVDIITKDGEVATSLSDGSYFGEICLLTNAKRVASVRAETYCNLYSLDSFHFLEVLENYPLMRRTMESV 694 The following BLAST results are available for this feature:
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Cyclic nucleotide gated channel 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024524 ID=SMED30024524|Name=Cyclic nucleotide gated channel 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2050bpback to top protein sequence of SMED30024524-orf-1 >SMED30024524-orf-1 ID=SMED30024524-orf-1|Name=SMED30024524-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=440bp MFNPLDSFRVNKTPKDNDDGTQSEQSLSEYIGGGAPGYRHPRLSASMYLKback to top Annotated Terms
The following terms have been associated with this transcript:
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