Ras-related protein

Overview


Name	Ras-related protein
Smed ID	SMED30024514
Length (bp)	781

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ras-related protein (SMED30024514) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras-related protein (SMED30024514) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras-related protein (SMED30024514) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras-related protein (SMED30024514) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30024514

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30024514	h1SMcG0001882	dd_Smed_v4_8100_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30024514	h1SMcG0001882	dd_Smed_v4_8100_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30024514	h1SMcG0001882	dd_Smed_v4_8100_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30024514	h1SMcG0001882	dd_Smed_v6_8100_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30024514	h1SMcG0001882	dd_Smed_v4_8100_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Ras-related protein vs. Ensembl Human
Match: MRAS (muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227])

HSP 1 Score: 129.413 bits (324), Expect = 8.235e-37
Identity = 67/114 (58.77%), Postives = 92/114 (80.70%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+I+V NKVDL   RK+T E+ KE+A + N+ Y+ETSAK PP+NVD AF ++VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR 176

HSP 2 Score: 43.8986 bits (102), Expect = 8.235e-37
Identity = 17/31 (54.84%), Postives = 23/31 (74.19%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E D +W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63

[Close]

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+I+V NKVDL   RK+T E+ KE+A + N+ Y+ETSAK PP+NVD AF ++VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR 176

HSP 2 Score: 43.8986 bits (102), Expect = 8.235e-37
Identity = 17/31 (54.84%), Postives = 23/31 (74.19%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E D +W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63

[Close]

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+I+V NKVDL   RK+T E+ KE+A + N+ Y+ETSAK PP+NVD AF ++VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR 176

HSP 2 Score: 43.8986 bits (102), Expect = 8.235e-37
Identity = 17/31 (54.84%), Postives = 23/31 (74.19%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E D +W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Human
Match: RRAS2 (RAS related 2 [Source:HGNC Symbol;Acc:HGNC:17271])

HSP 1 Score: 114.005 bits (284), Expect = 7.647e-31
Identity = 63/115 (54.78%), Postives = 89/115 (77.39%), Query Frame = 3

Query:  135 NVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
             + +LDTAGQ+ F AMR+QYMR G+GFL++FS+TDR SF+ +    + ILR KD++ FP+I++GNK DL  +R+VT+EE ++LA++L V YME SAK   +NVD AF E+VR+IR
Sbjct:   44 RLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIR 157

[Close]

BLAST of Ras-related protein vs. Ensembl Human
Match: RRAS2 (RAS related 2 [Source:HGNC Symbol;Acc:HGNC:17271])

HSP 1 Score: 113.235 bits (282), Expect = 1.372e-30
Identity = 63/114 (55.26%), Postives = 89/114 (78.07%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ F AMR+QYMR G+GFL++FS+TDR SF+ +    + ILR KD++ FP+I++GNK DL  +R+VT+EE ++LA++L V YME SAK   +NVD AF E+VR+IR
Sbjct:   29 LDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIR 141

[Close]

BLAST of Ras-related protein vs. Ensembl Celegans
Match: ras-2 (GTP binding protein; R-RAS related [Source:UniProtKB/TrEMBL;Acc:G5EGA7])

HSP 1 Score: 122.479 bits (306), Expect = 2.040e-34
Identity = 65/112 (58.04%), Postives = 88/112 (78.57%), Query Frame = 3

Query:  144 VLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            VLDTAGQ+ FSAMR+QY+R G GFL++FS+T+R SF+    LY  +LR KD+  +PV++V NKVDL  +R V+E+E +ELA +L + Y+ETSAK PPVNVD AF E+VR++R
Sbjct:   69 VLDTAGQEEFSAMREQYIRGGRGFLLVFSVTERKSFEEAHKLYNQVLRVKDRSEYPVLLVANKVDLINQRVVSEQEGRELAAQLKLMYIETSAKEPPVNVDAAFHELVRIVR 180

HSP 2 Score: 41.9726 bits (97), Expect = 2.040e-34
Identity = 18/29 (62.07%), Postives = 21/29 (72.41%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWC 87
            +FQ+ FV+ YDPTIED YIQ  E DG W 
Sbjct:   37 FFQKQFVDYYDPTIEDQYIQHCEIDGNWV 65

[Close]

Query:  144 VLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            VLDTAGQ+ FSAMR+QY+R G GFL++FS+T+R SF+    LY  +LR KD+  +PV++V NKVDL  +R V+E+E +ELA +L + Y+ETSAK PPVNVD AF E+VR++R
Sbjct:   69 VLDTAGQEEFSAMREQYIRGGRGFLLVFSVTERKSFEEAHKLYNQVLRVKDRSEYPVLLVANKVDLINQRVVSEQEGRELAAQLKLMYIETSAKEPPVNVDAAFHELVRIVR 180

HSP 2 Score: 41.9726 bits (97), Expect = 2.040e-34
Identity = 18/29 (62.07%), Postives = 21/29 (72.41%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWC 87
            +FQ+ FV+ YDPTIED YIQ  E DG W 
Sbjct:   37 FFQKQFVDYYDPTIEDQYIQHCEIDGNWV 65

[Close]

BLAST of Ras-related protein vs. Ensembl Celegans
Match: ras-1 (GTP binding protein; R-RAS related; R-ras1 homolog [Source:UniProtKB/TrEMBL;Acc:G5EBK8])

HSP 1 Score: 117.472 bits (293), Expect = 4.327e-32
Identity = 63/117 (53.85%), Postives = 88/117 (75.21%), Query Frame = 3

Query:  129 LLNVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            L  + +LDTAGQ+ FS MR+QY+R G GFL++F++TDRNSF+ V+ L++ I R KD+++FP+I+VGNK DL  ER V   EA+ELA  L++ Y+E SAK    NVD AF ++VRL+R
Sbjct:   64 LCKLEILDTAGQEEFSTMREQYLRTGSGFLIVFAVTDRNSFEEVKKLHELICRIKDRDDFPIILVGNKADLENERHVARHEAEELAHRLSIPYLECSAKIRK-NVDEAFFDIVRLVR 179

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BLAST of Ras-related protein vs. Ensembl Celegans
Match: let-60 (Ras protein let-60 [Source:UniProtKB/Swiss-Prot;Acc:P22981])

HSP 1 Score: 83.5741 bits (205), Expect = 1.033e-21
Identity = 50/114 (43.86%), Postives = 73/114 (64.04%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ +SAMR QYMR G+GFL++F++ +  SF+ V +  + I R KD ++ P+++VGNK DL   R V      E AK   +  ++TSAK   + VD AF  +VR IR
Sbjct:   53 LDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNEAKSFENVANYREQIRRVKDSDDVPMVLVGNKCDL-SSRSVDFRTVSETAKGYGIPNVDTSAK-TRMGVDEAFYTLVREIR 164

HSP 2 Score: 37.7354 bits (86), Expect = 1.033e-21
Identity = 19/37 (51.35%), Postives = 24/37 (64.86%), Query Frame = 1

Query:    4 FQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTGLVDML 114
             Q  FVE+YDPTIED+Y +    DGE C    L+D+L
Sbjct:   24 IQNHFVEEYDPTIEDSYRKQVVIDGETC----LLDIL 56

[Close]

BLAST of Ras-related protein vs. Ensembl Celegans
Match: rap-1 (Ras-related protein Rap-1 [Source:UniProtKB/Swiss-Prot;Acc:Q18246])

HSP 1 Score: 80.4925 bits (197), Expect = 3.939e-21
Identity = 48/113 (42.48%), Postives = 76/113 (67.26%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLI 476
            + +LDTAG + F+AMR  YM+ G GF++++SIT +++F  +  L   ILR KD +  P+I+VGNK DL +ER V +++ + LA++    ++ETSAK   +NV   F ++VR I
Sbjct:   53 LEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLMDLRDQILRVKDTDEVPMILVGNKCDLEDERVVGKDQGQNLARQFGSAFLETSAK-AKINVSEVFYDLVRQI 164

HSP 2 Score: 39.2762 bits (90), Expect = 3.939e-21
Identity = 17/31 (54.84%), Postives = 21/31 (67.74%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            + Q  FVE YDPTIED+Y +  E DG+ C L
Sbjct:   23 FVQGIFVEKYDPTIEDSYRKQVEVDGQQCML 53

[Close]

BLAST of Ras-related protein vs. Ensembl Fly
Match: Ras64B (gene:FBgn0003206 transcript:FBtr0073212)

HSP 1 Score: 105.916 bits (263), Expect = 7.681e-28
Identity = 58/125 (46.40%), Postives = 89/125 (71.20%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIRFILISIKILAE 512
            + +LDTAGQ+ FSAMR+QYMR G+GFL++F++ D +SF  +    + ILR KD++ FP+++VGNK DL  +++V+ EEA+  ++ L + Y+E SAK   VNVD AF E+VR++R   I+ +   E
Sbjct:   55 LDILDTAGQEEFSAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEEAQNTSRNLMIPYIECSAK-LRVNVDQAFHELVRIVRKFQIAERPFIE 178

[Close]

BLAST of Ras-related protein vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0303154)

HSP 1 Score: 89.3521 bits (220), Expect = 2.026e-23
Identity = 53/113 (46.90%), Postives = 80/113 (70.80%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLI 476
            + +LDTAG + F+AMR  YM+ G GF++++SIT +++F  ++ L + ILR KD ++ P+++VGNK DL EER V +E  K LA + N  +METSAK   VNV++ F ++VR I
Sbjct:   53 LEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAK-AKVNVNDIFYDLVRQI 164

HSP 2 Score: 38.5058 bits (88), Expect = 2.026e-23
Identity = 17/31 (54.84%), Postives = 21/31 (67.74%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            + Q  FVE YDPTIED+Y +  E DG+ C L
Sbjct:   23 FVQCIFVEKYDPTIEDSYRKQVEVDGQQCML 53

[Close]

BLAST of Ras-related protein vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0072867)

HSP 1 Score: 89.3521 bits (220), Expect = 2.026e-23
Identity = 53/113 (46.90%), Postives = 80/113 (70.80%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLI 476
            + +LDTAG + F+AMR  YM+ G GF++++SIT +++F  ++ L + ILR KD ++ P+++VGNK DL EER V +E  K LA + N  +METSAK   VNV++ F ++VR I
Sbjct:   53 LEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAK-AKVNVNDIFYDLVRQI 164

HSP 2 Score: 38.5058 bits (88), Expect = 2.026e-23
Identity = 17/31 (54.84%), Postives = 21/31 (67.74%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            + Q  FVE YDPTIED+Y +  E DG+ C L
Sbjct:   23 FVQCIFVEKYDPTIEDSYRKQVEVDGQQCML 53

[Close]

BLAST of Ras-related protein vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0332671)

HSP 1 Score: 89.3521 bits (220), Expect = 2.026e-23
Identity = 53/113 (46.90%), Postives = 80/113 (70.80%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLI 476
            + +LDTAG + F+AMR  YM+ G GF++++SIT +++F  ++ L + ILR KD ++ P+++VGNK DL EER V +E  K LA + N  +METSAK   VNV++ F ++VR I
Sbjct:   53 LEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAK-AKVNVNDIFYDLVRQI 164

HSP 2 Score: 38.5058 bits (88), Expect = 2.026e-23
Identity = 17/31 (54.84%), Postives = 21/31 (67.74%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            + Q  FVE YDPTIED+Y +  E DG+ C L
Sbjct:   23 FVQCIFVEKYDPTIEDSYRKQVEVDGQQCML 53

[Close]

BLAST of Ras-related protein vs. Ensembl Fly
Match: Rala (gene:FBgn0015286 transcript:FBtr0070583)

HSP 1 Score: 94.3597 bits (233), Expect = 3.031e-23
Identity = 53/116 (45.69%), Postives = 77/116 (66.38%), Query Frame = 3

Query:  132 LNVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + + +LDTAGQ+ ++A+R  Y R G+GFL +FSITD  SFQ  +   + ILR K+ E+ P ++VGNK DL ++RKV   E +  A++  V Y+ETSAK    NVD  F +++R IR
Sbjct:   59 VQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGNKCDLNDKRKVPLSECQLRAQQWAVPYVETSAKTRE-NVDKVFFDLMREIR 173

[Close]

BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: si:ch73-116o1.2 (si:ch73-116o1.2 [Source:ZFIN;Acc:ZDB-GENE-110411-67])

HSP 1 Score: 129.798 bits (325), Expect = 6.960e-38
Identity = 67/114 (58.77%), Postives = 91/114 (79.82%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL++FS+TD+ SF+ V   ++ ILR KD+E+FP+++V NKVDL   RKVT E+  E+A + N+ Y+ETSAK PP+NV+ AF E+VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKVTNEQGCEMAAKHNITYIETSAKDPPMNVERAFHELVRVIR 176

HSP 2 Score: 46.595 bits (109), Expect = 6.960e-38
Identity = 18/31 (58.06%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E DG+W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDGQWAIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: MRAS (si:ch73-116o1.2 [Source:ZFIN;Acc:ZDB-GENE-110411-67])

HSP 1 Score: 129.798 bits (325), Expect = 6.960e-38
Identity = 67/114 (58.77%), Postives = 91/114 (79.82%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL++FS+TD+ SF+ V   ++ ILR KD+E+FP+++V NKVDL   RKVT E+  E+A + N+ Y+ETSAK PP+NV+ AF E+VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKVTNEQGCEMAAKHNITYIETSAKDPPMNVERAFHELVRVIR 176

HSP 2 Score: 46.595 bits (109), Expect = 6.960e-38
Identity = 18/31 (58.06%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E DG+W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDGQWAIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: mras (muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-GENE-050208-495])

HSP 1 Score: 129.798 bits (325), Expect = 7.435e-38
Identity = 66/114 (57.89%), Postives = 92/114 (80.70%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL++FS+TD+ SF+ V   ++ ILR KD+E+FP+++V NKVDL   RK+T E+ +E+A + ++ Y+ETSAK PP+NVD AF E+VR+IR
Sbjct:   64 LDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKITSEQGREMASKHSITYIETSAKDPPMNVDKAFHELVRVIR 177

HSP 2 Score: 46.9802 bits (110), Expect = 7.435e-38
Identity = 18/31 (58.06%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E DG+W  L
Sbjct:   34 FFQKIFVPDYDPTIEDSYLKHTEIDGQWAIL 64

[Close]

BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: mras (muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-GENE-050208-495])

HSP 1 Score: 129.798 bits (325), Expect = 7.454e-38
Identity = 66/114 (57.89%), Postives = 92/114 (80.70%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL++FS+TD+ SF+ V   ++ ILR KD+E+FP+++V NKVDL   RK+T E+ +E+A + ++ Y+ETSAK PP+NVD AF E+VR+IR
Sbjct:   39 LDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKITSEQGREMASKHSITYIETSAKDPPMNVDKAFHELVRVIR 152

HSP 2 Score: 46.595 bits (109), Expect = 7.454e-38
Identity = 18/31 (58.06%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E DG+W  L
Sbjct:    9 FFQKIFVPDYDPTIEDSYLKHTEIDGQWAIL 39

[Close]

BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: rras2 (RAS related 2 [Source:ZFIN;Acc:ZDB-GENE-050417-352])

HSP 1 Score: 114.775 bits (286), Expect = 5.265e-31
Identity = 64/115 (55.65%), Postives = 90/115 (78.26%), Query Frame = 3

Query:  135 NVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
             + +LDTAGQ+ F AMR+QYMR G+GFL++FS+TDR SF+ +    + ILR KD++ FP+I+VGNK DL ++R+VT+EE ++LA++L V YME SAK   +NVD AF E+VR+IR
Sbjct:   61 RLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILVGNKADLEQQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIR 174

[Close]

BLAST of Ras-related protein vs. Ensembl Xenopus
Match: thbs3 (thrombospondin 3 [Source:Xenbase;Acc:XB-GENE-5761978])

HSP 1 Score: 129.798 bits (325), Expect = 1.084e-37
Identity = 68/114 (59.65%), Postives = 91/114 (79.82%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+I+V NKVDL   RKV+ E+ KE+A + N+ Y+ETSAK PP NVD AF E+VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLIHLRKVSSEQGKEMATKHNIPYIETSAKDPPQNVDKAFHELVRVIR 176

HSP 2 Score: 46.595 bits (109), Expect = 1.084e-37
Identity = 18/31 (58.06%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E DG+W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDGQWAIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Xenopus
Match: tle1 (transducin like enhancer of split 1 [Source:Xenbase;Acc:XB-GENE-868100])

HSP 1 Score: 108.612 bits (270), Expect = 2.007e-28
Identity = 61/114 (53.51%), Postives = 84/114 (73.68%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ F AMR+QYMR G+GFL++F+I DR SF  +   +  ILR KD++ FP+I+VGNK DL  +R+VT+EEA   A+E ++ YME SAK   +NVD +F E+VR IR
Sbjct:   63 LDILDTAGQEEFGAMREQYMRTGEGFLLIFAINDRGSFNEMSKFHTQILRVKDRDEFPMILVGNKADLDLQRQVTKEEALSFARENHIPYMEASAK-IRLNVDESFHELVRAIR 175

[Close]

BLAST of Ras-related protein vs. Ensembl Xenopus
Match: rpp38 (ribonuclease P/MRP 38kDa subunit [Source:Xenbase;Acc:XB-GENE-943258])

HSP 1 Score: 95.9005 bits (237), Expect = 1.350e-23
Identity = 55/116 (47.41%), Postives = 79/116 (68.10%), Query Frame = 3

Query:  132 LNVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + + +LDTAGQ+ ++A+R  Y R G+GFL +FSIT++ SF       + ILR K+ EN P ++VGNK DL ++R+V+ EEAK  A + NV Y+ETSAK    NVD  F +++R IR
Sbjct:   62 VQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEQESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKSRADQWNVNYVETSAK-TRANVDKVFFDLMREIR 176

[Close]

BLAST of Ras-related protein vs. Ensembl Xenopus
Match: krasl (Kirsten rat sarcoma viral oncogene homolog like [Source:NCBI gene;Acc:100485959])

HSP 1 Score: 92.8189 bits (229), Expect = 2.040e-23
Identity = 53/114 (46.49%), Postives = 78/114 (68.42%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ +SAMR QYMR G+GFL +F+I +  SF+ + H  + I R KD E+ P+++VGNK DL   R V  ++A++LA+   + ++ETSAK     VD+AF  +VR IR
Sbjct:   53 LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL-PSRTVDTKQAQDLARSYGIPFIETSAKTRQ-GVDDAFYTLVREIR 164

HSP 2 Score: 35.8094 bits (81), Expect = 2.040e-23
Identity = 18/37 (48.65%), Postives = 24/37 (64.86%), Query Frame = 1

Query:    4 FQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTGLVDML 114
             Q  FV++YDPTIED+Y +    DGE C    L+D+L
Sbjct:   24 IQNHFVDEYDPTIEDSYRKQVVIDGETC----LLDIL 56

[Close]

BLAST of Ras-related protein vs. Ensembl Xenopus
Match: krasl (Kirsten rat sarcoma viral oncogene homolog like [Source:NCBI gene;Acc:100485959])

HSP 1 Score: 90.5077 bits (223), Expect = 9.036e-23
Identity = 52/114 (45.61%), Postives = 78/114 (68.42%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ +SAMR QYMR G+GFL +F+I +  SF+ + H  + I R KD E+ P+++VGNK DL   R V  ++A++LA+   + ++ETSAK     V++AF  +VR IR
Sbjct:   53 LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL-PSRTVDTKQAQDLARSYGIPFIETSAKTRQ-RVEDAFYTLVREIR 164

HSP 2 Score: 35.8094 bits (81), Expect = 9.036e-23
Identity = 18/37 (48.65%), Postives = 24/37 (64.86%), Query Frame = 1

Query:    4 FQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTGLVDML 114
             Q  FV++YDPTIED+Y +    DGE C    L+D+L
Sbjct:   24 IQNHFVDEYDPTIEDSYRKQVVIDGETC----LLDIL 56

[Close]

BLAST of Ras-related protein vs. Ensembl Mouse
Match: Mras (muscle and microspikes RAS [Source:MGI Symbol;Acc:MGI:1100856])

HSP 1 Score: 127.102 bits (318), Expect = 3.452e-36
Identity = 66/114 (57.89%), Postives = 91/114 (79.82%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+I+V NKVDL   RKVT ++ KE+A + N+ Y+ETSAK PP+NVD  F ++VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIR 176

HSP 2 Score: 43.8986 bits (102), Expect = 3.452e-36
Identity = 17/31 (54.84%), Postives = 23/31 (74.19%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E D +W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63

[Close]

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+I+V NKVDL   RKVT ++ KE+A + N+ Y+ETSAK PP+NVD  F ++VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIR 176

HSP 2 Score: 43.8986 bits (102), Expect = 3.452e-36
Identity = 17/31 (54.84%), Postives = 23/31 (74.19%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E D +W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63

[Close]

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+I+V NKVDL   RKVT ++ KE+A + N+ Y+ETSAK PP+NVD  F ++VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIR 176

HSP 2 Score: 43.8986 bits (102), Expect = 3.452e-36
Identity = 17/31 (54.84%), Postives = 23/31 (74.19%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E D +W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Mouse
Match: Rras2 (related RAS viral (r-ras) oncogene 2 [Source:MGI Symbol;Acc:MGI:1914172])

HSP 1 Score: 113.62 bits (283), Expect = 1.696e-30
Identity = 63/115 (54.78%), Postives = 89/115 (77.39%), Query Frame = 3

Query:  135 NVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
             + +LDTAGQ+ F AMR+QYMR G+GFL++FS+TDR SF+ +    + ILR KD++ FP+I++GNK DL  +R+VT+EE ++LA++L V YME SAK   +NVD AF E+VR+IR
Sbjct:   63 RLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIR 176

[Close]

BLAST of Ras-related protein vs. Ensembl Mouse
Match: Rras (related RAS viral (r-ras) oncogene [Source:MGI Symbol;Acc:MGI:98179])

HSP 1 Score: 107.842 bits (268), Expect = 4.226e-28
Identity = 56/114 (49.12%), Postives = 80/114 (70.18%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ F AMR+QYMR G+GFL++F+I DR SF  V  L+  ILR KD+++FP+++VGNK DL  +R+V   EA   +   ++ Y E SAK   +NVD AF ++VR +R
Sbjct:   79 LDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAK-LRLNVDEAFEQLVRAVR 191

[Close]

BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|O14807|RASM_HUMAN (Ras-related protein M-Ras OS=Homo sapiens OX=9606 GN=MRAS PE=1 SV=2)

HSP 1 Score: 129.413 bits (324), Expect = 3.485e-36
Identity = 67/114 (58.77%), Postives = 92/114 (80.70%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+I+V NKVDL   RK+T E+ KE+A + N+ Y+ETSAK PP+NVD AF ++VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR 176

HSP 2 Score: 43.8986 bits (102), Expect = 3.485e-36
Identity = 17/31 (54.84%), Postives = 23/31 (74.19%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E D +W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63

[Close]

BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|O08989|RASM_MOUSE (Ras-related protein M-Ras OS=Mus musculus OX=10090 GN=Mras PE=1 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 2.008e-35
Identity = 66/114 (57.89%), Postives = 91/114 (79.82%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+I+V NKVDL   RKVT ++ KE+A + N+ Y+ETSAK PP+NVD  F ++VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIR 176

HSP 2 Score: 43.8986 bits (102), Expect = 2.008e-35
Identity = 17/31 (54.84%), Postives = 23/31 (74.19%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E D +W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63

[Close]

BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|P97538|RASM_RAT (Ras-related protein M-Ras OS=Rattus norvegicus OX=10116 GN=Mras PE=1 SV=2)

HSP 1 Score: 126.716 bits (317), Expect = 2.145e-35
Identity = 66/114 (57.89%), Postives = 91/114 (79.82%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+I+V NKVDL   RKVT ++ KE+A + N+ Y+ETSAK PP+NVD  F ++VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIR 176

HSP 2 Score: 43.8986 bits (102), Expect = 2.145e-35
Identity = 17/31 (54.84%), Postives = 23/31 (74.19%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E D +W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDNQWAIL 63

[Close]

BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|P62071|RRAS2_MOUSE (Ras-related protein R-Ras2 OS=Mus musculus OX=10090 GN=Rras2 PE=1 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.186e-29
Identity = 63/115 (54.78%), Postives = 89/115 (77.39%), Query Frame = 3

Query:  135 NVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
             + +LDTAGQ+ F AMR+QYMR G+GFL++FS+TDR SF+ +    + ILR KD++ FP+I++GNK DL  +R+VT+EE ++LA++L V YME SAK   +NVD AF E+VR+IR
Sbjct:   63 RLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIR 176

[Close]

BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|P62070|RRAS2_HUMAN (Ras-related protein R-Ras2 OS=Homo sapiens OX=9606 GN=RRAS2 PE=1 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.186e-29
Identity = 63/115 (54.78%), Postives = 89/115 (77.39%), Query Frame = 3

Query:  135 NVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
             + +LDTAGQ+ F AMR+QYMR G+GFL++FS+TDR SF+ +    + ILR KD++ FP+I++GNK DL  +R+VT+EE ++LA++L V YME SAK   +NVD AF E+VR+IR
Sbjct:   63 RLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIR 176

[Close]

BLAST of Ras-related protein vs. TrEMBL
Match: R7U636 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_154233 PE=4 SV=1)

HSP 1 Score: 135.961 bits (341), Expect = 1.576e-38
Identity = 72/114 (63.16%), Postives = 92/114 (80.70%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMRKGDGFL++FS+TDR S++ V H Y  ILR KD++ +P+I+VGNKVDL   RKVT ++ KELA  L + Y+ETSAK PP+NVD AF EVV++IR
Sbjct:   61 LDVLDTAGQEEFSAMREQYMRKGDGFLLVFSVTDRQSYENVHHFYTQILRVKDRDTYPMILVGNKVDLVHLRKVTTDQGKELATNLRIPYIETSAKDPPLNVDAAFHEVVKVIR 174

HSP 2 Score: 53.1434 bits (126), Expect = 1.576e-38
Identity = 21/31 (67.74%), Postives = 26/31 (83.87%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV+DYDPTIED+YIQ  E DG+WC L
Sbjct:   31 FFQKMFVQDYDPTIEDSYIQHTEIDGQWCIL 61

[Close]

BLAST of Ras-related protein vs. TrEMBL
Match: A0A210Q323 (Ras-related protein M-Ras OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT19738 PE=4 SV=1)

HSP 1 Score: 132.494 bits (332), Expect = 4.147e-38
Identity = 67/114 (58.77%), Postives = 92/114 (80.70%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMRKGDGFL+++S+TDR S++ + + Y  ILR KD++N+P+++V NKVDL   RKV++E    LA+ L +QY+ETSAK PP+NVD AF E+VR+IR
Sbjct:   62 LDVLDTAGQEEFSAMREQYMRKGDGFLLVYSVTDRQSYENIENFYSQILRVKDRDNYPMVLVANKVDLVALRKVSDELGNNLARHLRLQYIETSAKGPPLNVDKAFHELVRVIR 175

HSP 2 Score: 55.0694 bits (131), Expect = 4.147e-38
Identity = 22/31 (70.97%), Postives = 27/31 (87.10%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FVEDYDPTIED+YIQ+ E DG+WC L
Sbjct:   32 FFQKMFVEDYDPTIEDSYIQNAEIDGKWCIL 62

[Close]

BLAST of Ras-related protein vs. TrEMBL
Match: A0A1S3JDF1 (ras-related protein M-Ras-like OS=Lingula unguis OX=7574 GN=LOC106171929 PE=4 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 1.013e-37
Identity = 69/114 (60.53%), Postives = 95/114 (83.33%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMRKGDGFL+++S+TDR S++ +R+ +  ILR KD++++P+++V NKVDL   RKV EE+ ++LA +L VQY+ETSAK PP+NVD AF EVVR+IR
Sbjct:   61 LDVLDTAGQEEFSAMREQYMRKGDGFLLVYSVTDRQSYENIRNFHTQILRVKDRDSYPMLLVANKVDLVHLRKVPEEQGRDLAIQLGVQYIETSAKDPPLNVDAAFHEVVRVIR 174

HSP 2 Score: 54.299 bits (129), Expect = 1.013e-37
Identity = 23/34 (67.65%), Postives = 27/34 (79.41%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTGL 102
            +FQ+ FV+DYDPTIED+YIQ  E DGEWC L  L
Sbjct:   31 FFQKMFVQDYDPTIEDSYIQHTEIDGEWCILDVL 64

[Close]

BLAST of Ras-related protein vs. TrEMBL
Match: A0A1S3JBY1 (ras-related protein M-Ras-like isoform X1 OS=Lingula unguis OX=7574 GN=LOC106159879 PE=4 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 1.128e-37
Identity = 69/114 (60.53%), Postives = 95/114 (83.33%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMRKGDGFL+++S+TDR S++ +R+ +  ILR KD++++P+++V NKVDL   RKV EE+ ++LA +L VQY+ETSAK PP+NVD AF EVVR+IR
Sbjct:   61 LDVLDTAGQEEFSAMREQYMRKGDGFLLVYSVTDRQSYENIRNFHTQILRVKDRDSYPMLLVANKVDLVHLRKVPEEQGRDLAIQLGVQYIETSAKDPPLNVDAAFHEVVRVIR 174

HSP 2 Score: 53.9138 bits (128), Expect = 1.128e-37
Identity = 23/34 (67.65%), Postives = 27/34 (79.41%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTGL 102
            +FQ+ FV+DYDPTIED+YIQ  E DGEWC L  L
Sbjct:   31 FFQKMFVQDYDPTIEDSYIQHTEIDGEWCILDVL 64

[Close]

BLAST of Ras-related protein vs. TrEMBL
Match: A0A212FEK5 (Ras-related protein M-Ras OS=Danaus plexippus plexippus OX=278856 GN=KGM_205714 PE=4 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 1.342e-37
Identity = 68/114 (59.65%), Postives = 90/114 (78.95%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMRKGDGFL+++S+TD+ SFQ +RH +  ILR KD+E +P+++  NKVDL   R V+EE  +ELA+ L   Y+ETSAK PP+NVD AF E+VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRKGDGFLLVYSVTDQQSFQNIRHFHTQILRVKDRETYPMLVAANKVDLVHARAVSEEAGRELARALGAPYIETSAKEPPLNVDRAFHELVRIIR 176

HSP 2 Score: 51.6026 bits (122), Expect = 1.342e-37
Identity = 21/31 (67.74%), Postives = 25/31 (80.65%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+YIQ  E DG+WC L
Sbjct:   33 FFQKLFVTDYDPTIEDSYIQHTEVDGQWCIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Cavefish
Match: si:ch73-116o1.2 (muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227])

HSP 1 Score: 129.798 bits (325), Expect = 6.979e-38
Identity = 66/114 (57.89%), Postives = 91/114 (79.82%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL++FS+TD+ SF+ V   ++ ILR KD+E+FP+++V NKVDL   RKVT ++  E+A + ++ Y+ETSAK PP+NVD AF E+VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKVTSDQGCEMAAKHSITYIETSAKDPPMNVDKAFHELVRVIR 176

HSP 2 Score: 46.595 bits (109), Expect = 6.979e-38
Identity = 18/31 (58.06%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E DG+W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDGQWAIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Cavefish
Match: mras (ras-related protein M-Ras [Source:NCBI gene;Acc:103031239])

HSP 1 Score: 129.413 bits (324), Expect = 7.900e-38
Identity = 66/114 (57.89%), Postives = 92/114 (80.70%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL++FS+TD+ SF+ V   ++ ILR KD+E+FP+++V NKVDL   RK+T E+ +E+A + ++ Y+ETSAK PP+NVD AF E+VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKITSEQGREMAMKHSITYIETSAKDPPMNVDKAFHELVRVIR 176

HSP 2 Score: 46.9802 bits (110), Expect = 7.900e-38
Identity = 18/31 (58.06%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E DG+W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDGQWAIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Cavefish
Match: rras2 (RAS related 2 [Source:NCBI gene;Acc:103027563])

HSP 1 Score: 114.39 bits (285), Expect = 7.007e-31
Identity = 62/115 (53.91%), Postives = 90/115 (78.26%), Query Frame = 3

Query:  135 NVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
             + +LDTAGQ+ F AMR+QYMR G+GFL++FS+TDR SF+ +    + ILR KD++ FP+I+VGNK DL ++R+V+++E ++LA++L V YME SAK   +NVD AF E+VR+IR
Sbjct:   62 RLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILVGNKADLEQQRQVSQDEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIR 175

[Close]

BLAST of Ras-related protein vs. Ensembl Cavefish
Match: rras (RAS related [Source:ZFIN;Acc:ZDB-GENE-041010-217])

HSP 1 Score: 109.383 bits (272), Expect = 5.333e-29
Identity = 59/114 (51.75%), Postives = 83/114 (72.81%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ F AMR+QYMR G+GFL++F++ D  S+  ++  +  ILR KD+++FP+++VGNK DL + R V+ EEA   A+E  + YME+SAK    NVD AFLEVVR IR
Sbjct:   64 LDILDTAGQEEFGAMREQYMRSGEGFLLVFALNDSGSYNEIQKFHTQILRVKDRDDFPMVLVGNKSDLDQHRVVSREEAMGFARENRIHYMESSAKNRH-NVDEAFLEVVRAIR 176

[Close]

BLAST of Ras-related protein vs. Ensembl Cavefish
Match: kras (GTPase KRas [Source:NCBI gene;Acc:103038241])

HSP 1 Score: 92.4337 bits (228), Expect = 1.334e-23
Identity = 53/114 (46.49%), Postives = 78/114 (68.42%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ +SAMR QYMR G+GFL +F+I +  SF+ + H  + I R KD E+ P+++VGNK DL   R V  ++A++LA+   + ++ETSAK     VD+AF  +VR IR
Sbjct:   53 LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL-PSRTVDTKQAQDLARSYGIPFIETSAKTRQ-GVDDAFYTLVREIR 164

HSP 2 Score: 35.8094 bits (81), Expect = 1.334e-23
Identity = 18/37 (48.65%), Postives = 24/37 (64.86%), Query Frame = 1

Query:    4 FQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTGLVDML 114
             Q  FV++YDPTIED+Y +    DGE C    L+D+L
Sbjct:   24 IQNHFVDEYDPTIEDSYRKQVVIDGETC----LLDIL 56

[Close]

BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005561.1 (pep scaffold:Pmarinus_7.0:GL481089:12431:17765:1 gene:ENSPMAG00000005048.1 transcript:ENSPMAT00000005561.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 127.872 bits (320), Expect = 2.619e-38
Identity = 63/114 (55.26%), Postives = 92/114 (80.70%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+E+FP+++V NKVDL   RK++ E+ +E+A + ++ Y+ETSAK PP+NVD AF ++VR+IR
Sbjct:   62 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVERFHQLILRVKDRESFPMVLVANKVDLLHLRKISTEQGQEMASKYDIPYIETSAKEPPLNVDKAFHQLVRVIR 175

HSP 2 Score: 47.7506 bits (112), Expect = 2.619e-38
Identity = 19/31 (61.29%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+YI+  E DG+W  L
Sbjct:   32 FFQKIFVPDYDPTIEDSYIKHAEIDGQWAIL 62

[Close]

BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: mras (muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-GENE-050208-495])

HSP 1 Score: 129.028 bits (323), Expect = 2.965e-38
Identity = 63/112 (56.25%), Postives = 90/112 (80.36%), Query Frame = 3

Query:  144 VLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
             LDTAGQ+ FSAMR+QYMR GDGFL+++S+TDR SF+ +   ++ ILR KDK++FP+++V NKVDL   RK++ E+ +++A + N+ Y+ETSAK PP+NVD AF E+VR+IR
Sbjct:   66 CLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDRTSFEHIDKFHQLILRVKDKDSFPMVLVANKVDLLHLRKISSEQGRDMAAKYNIPYIETSAKDPPLNVDQAFHELVRVIR 177

HSP 2 Score: 46.2098 bits (108), Expect = 2.965e-38
Identity = 18/31 (58.06%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E DG+W  L
Sbjct:   33 FFQKIFVADYDPTIEDSYLKHTEIDGQWAIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000518.1 (pep scaffold:Pmarinus_7.0:GL479781:11597:21619:-1 gene:ENSPMAG00000000465.1 transcript:ENSPMAT00000000518.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 127.872 bits (320), Expect = 3.497e-38
Identity = 64/114 (56.14%), Postives = 92/114 (80.70%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL+++S+TD+ SF+ V   ++ ILR KD+++FP+I+V NKVDL   RK++ E+ +E+A + ++ Y+ETSAK PP+NVD AF E+VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVERFHQLILRVKDRDSFPMILVANKVDLMHLRKISSEQGQEMAAKYSIPYIETSAKDPPLNVDKAFQELVRVIR 176

HSP 2 Score: 46.9802 bits (110), Expect = 3.497e-38
Identity = 19/31 (61.29%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+YI+  E DG+W  L
Sbjct:   33 FFQKIFVVDYDPTIEDSYIKHTEIDGQWAIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: hrasb (HRas proto-oncogene, GTPase b [Source:ZFIN;Acc:ZDB-GENE-050522-466])

HSP 1 Score: 87.8113 bits (216), Expect = 2.621e-22
Identity = 51/114 (44.74%), Postives = 77/114 (67.54%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ +SAMR QYMR G+GFL +F+I +  SF+ +    + I R KD ++ P+++VGNK DL   R V  ++A++LA+   + Y+ETSAK     V++AF  +VR IR
Sbjct:   57 LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL-PARTVDTKQAQDLARSYGIPYVETSAKTRQ-GVEDAFYTLVREIR 168

HSP 2 Score: 33.4982 bits (75), Expect = 2.621e-22
Identity = 17/37 (45.95%), Postives = 23/37 (62.16%), Query Frame = 1

Query:    4 FQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTGLVDML 114
             Q  FV++YDPTIED+Y +    D E C    L+D+L
Sbjct:   28 IQNHFVDEYDPTIEDSYRKQVVIDSETC----LLDIL 60

[Close]

BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: ralba (v-ral simian leukemia viral oncogene homolog Ba (ras related) [Source:ZFIN;Acc:ZDB-GENE-040801-267])

HSP 1 Score: 87.4261 bits (215), Expect = 3.092e-21
Identity = 50/116 (43.10%), Postives = 76/116 (65.52%), Query Frame = 3

Query:  132 LNVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + + +LDTAGQ+ ++A+R  Y R G+GFL +FSI +  SF       + ILR K+ ++ P ++VGNK DL E R+V+ EEA+  A++  V Y+ETSAK    NVD  F +++R +R
Sbjct:   61 VQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSICEHESFAATLEFREQILRVKEDDSVPFLLVGNKSDLEERRQVSSEEARARAEQWRVSYVETSAK-TRANVDKVFFDLMRDVR 175

[Close]

BLAST of Ras-related protein vs. Ensembl Yeast
Match: RAS1 (GTPase involved in G-protein signaling in adenylate cyclase activation; plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes; relative distribution to the nucleus increases upon DNA replication stress; RAS1 has a paralog, RAS2, that arose from the whole genome duplication [Source:SGD;Acc:S000005627])

HSP 1 Score: 106.686 bits (265), Expect = 9.143e-28
Identity = 59/112 (52.68%), Postives = 84/112 (75.00%), Query Frame = 3

Query:  144 VLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            +LDTAGQ+ +SAMR+QYMR G+GFL+++S+T RNSF  +   Y+ I R KD +  PV++VGNK+DL  ER+V+ E+   LAK+LN  ++ETSAK   +NVD AF  ++RL+R
Sbjct:   62 ILDTAGQEEYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDYIPVVVVGNKLDLENERQVSYEDGLRLAKQLNAPFLETSAK-QAINVDEAFYSLIRLVR 172

[Close]

BLAST of Ras-related protein vs. Ensembl Yeast
Match: RAS2 (GTP-binding protein; regulates nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes; RAS2 has a paralog, RAS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005042])

HSP 1 Score: 99.7525 bits (247), Expect = 4.180e-25
Identity = 52/112 (46.43%), Postives = 82/112 (73.21%), Query Frame = 3

Query:  144 VLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            +LDTAGQ+ +SAMR+QYMR G+GFL+++SIT ++S   +   Y+ ILR KD +  P+++VGNK DL  E++V+ ++   +AK++N  ++ETSAK   +NV+ AF  + RL+R
Sbjct:   62 ILDTAGQEEYSAMREQYMRNGEGFLLVYSITSKSSLDELMTYYQQILRVKDTDYVPIVVVGNKSDLENEKQVSYQDGLNMAKQMNAPFLETSAK-QAINVEEAFYTLARLVR 172

[Close]

BLAST of Ras-related protein vs. Ensembl Yeast
Match: RSR1 (GTP-binding protein of the Ras superfamily; required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases [Source:SGD;Acc:S000003384])

HSP 1 Score: 74.3294 bits (181), Expect = 3.167e-16
Identity = 47/117 (40.17%), Postives = 77/117 (65.81%), Query Frame = 3

Query:  129 LLNVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXN-VQYMETSAKPPPVNVDNAFLEVVRLI 476
            + ++ +LDTAG   F+AMR+ Y++ G GFL+++S+TDR S + +  L + +LR KD +  P++++GNK DL  ER ++ EE  E++ +   V + ETSA     NVD  F+++VR I
Sbjct:   50 VFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDSDRVPMVLIGNKADLINERVISVEEGIEVSSKWGRVPFYETSALLRS-NVDEVFVDLVRQI 165

[Close]

BLAST of Ras-related protein vs. Ensembl Yeast
Match: GSP1 (Ran GTPase; GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Srm1p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; GSP1 has a paralog, GSP2, that arose from the whole genome duplication [Source:SGD;Acc:S000004284])

HSP 1 Score: 58.5362 bits (140), Expect = 7.210e-11
Identity = 34/109 (31.19%), Postives = 61/109 (55.96%), Query Frame = 3

Query:  144 VLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVR 470
            V DTAGQ+ F  +R  Y       ++MF +T R +++ V + ++D++R    EN P+++ GNKVD+  + +  + +     ++ N+QY + SAK    N +  FL + R
Sbjct:   65 VWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRV--CENIPIVLCGNKVDV--KERKVKAKTITFHRKKNLQYYDISAK-SNYNFEKPFLWLAR 168

[Close]

BLAST of Ras-related protein vs. Ensembl Yeast
Match: GSP2 (GTP binding protein (mammalian Ranp homolog); involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); not required for viability; protein abundance increases in response to DNA replication stress; GSP2 has a paralog, GSP1, that arose from the whole genome duplication [Source:SGD;Acc:S000005711])

HSP 1 Score: 58.151 bits (139), Expect = 8.437e-11
Identity = 34/109 (31.19%), Postives = 61/109 (55.96%), Query Frame = 3

Query:  144 VLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVR 470
            V DTAGQ+ F  +R  Y       ++MF +T R +++ V + ++D++R    EN P+++ GNKVD+  + +  + +     ++ N+QY + SAK    N +  FL + R
Sbjct:   66 VWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRV--CENIPIVLCGNKVDV--KERKVKAKTITFHRKKNLQYYDISAK-SNYNFEKPFLWLAR 169

[Close]

BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO39171 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAS1])

HSP 1 Score: 119.398 bits (298), Expect = 2.386e-33
Identity = 65/122 (53.28%), Postives = 90/122 (73.77%), Query Frame = 3

Query:  135 NVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIRFILISIK 500
            ++ +LDTAGQ+ FSAMR+QYMR G+GFL++FS+TDR+SF+ +   Y  ILR KD+  FP+II GNK DL  ER V+  E +ELA++L +QY+ETSAK    NVD AF ++VR IR   ++ +
Sbjct:   60 HLDILDTAGQEEFSAMREQYMRSGEGFLLVFSVTDRSSFEEINKFYNQILRVKDRTEFPMIICGNKSDLEYERTVSTAEGQELARQLRIQYLETSAK-QRTNVDQAFHDLVRAIRRFTVATE 180

[Close]

BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO32914 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STP5])

HSP 1 Score: 90.5077 bits (223), Expect = 2.094e-23
Identity = 54/114 (47.37%), Postives = 77/114 (67.54%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ +SAMR QYMR G+GFL +F++ +  SF+ +    + I R KD E  P+++VGNK DL  +R V+  +A+ELAK  N+ + ETSAK     VD+AF  +VR IR
Sbjct:   53 LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAVNNSKSFEDINQYREQIKRVKDAEEVPMVLVGNKCDL-PQRTVSTSDAQELAKSYNIPFQETSAKTRQ-GVDDAFYTLVREIR 164

HSP 2 Score: 35.8094 bits (81), Expect = 2.094e-23
Identity = 18/37 (48.65%), Postives = 24/37 (64.86%), Query Frame = 1

Query:    4 FQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTGLVDML 114
             Q  FV++YDPTIED+Y +    DGE C    L+D+L
Sbjct:   24 IQNHFVDEYDPTIEDSYRKQVVIDGETC----LLDIL 56

[Close]

BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO39047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB93])

HSP 1 Score: 82.0333 bits (201), Expect = 6.558e-22
Identity = 49/114 (42.98%), Postives = 81/114 (71.05%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXX-XNVQYMETSAKPPPVNVDNAFLEVVRLI 476
            + +LDTAG + F+AMR  YM+ G GF++++SIT +++F  ++ L + ILR KD ++ P+++VGNK DL +ER V +++ + LAK+  N  ++ETSAK   +NV+  F ++VR I
Sbjct:   53 LEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEDERVVGKDQGQNLAKQFANCTFLETSAK-AKINVNEIFYDLVRQI 165

HSP 2 Score: 39.2762 bits (90), Expect = 6.558e-22
Identity = 17/31 (54.84%), Postives = 21/31 (67.74%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            + Q  FVE YDPTIED+Y +  E DG+ C L
Sbjct:   23 FVQGIFVEKYDPTIEDSYRKQVEVDGQQCML 53

[Close]

BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO36396 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIQ7])

HSP 1 Score: 88.1965 bits (217), Expect = 1.915e-21
Identity = 52/114 (45.61%), Postives = 77/114 (67.54%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ  F+AMR+QYMR G+GF++++SITDR+SF +       I R +  ++ P+++VGNK DL  +R+VT +E +ELA   +  + ETSA      VD+AF  +VR IR
Sbjct:   50 LDILDTAGQQEFTAMREQYMRNGEGFIIIYSITDRSSFNLAAQYKDQIERVRRTDDIPIVLVGNKDDLEGKREVTTQEGQELAHRFDCPFFETSACQRHF-VDDAFHGLVREIR 162

[Close]

BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO45827 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRV2])

HSP 1 Score: 87.8113 bits (216), Expect = 2.644e-21
Identity = 52/116 (44.83%), Postives = 73/116 (62.93%), Query Frame = 3

Query:  132 LNVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
              + +LDTAGQ+ ++A+R  Y R G+GFL +FSIT+  SF       + ILR K  +  P ++VGNK DL ++R+VT EE +  A E  V Y+ETSAK    NVD  F +++R IR
Sbjct:   59 CQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEPESFAATTEFREQILRVKGDDKIPFLLVGNKSDLTDKRQVTSEEGQSKADEWGVPYVETSAKTRS-NVDKVFFDLMREIR 173

HSP 2 Score: 31.187 bits (69), Expect = 2.644e-21
Identity = 13/26 (50.00%), Postives = 17/26 (65.38%), Query Frame = 1

Query:   16 FVEDYDPTIEDTYIQSKEFDGEWCDL 93
            FVEDY+PT  D+Y +    DGE C +
Sbjct:   36 FVEDYEPTKADSYRKKAILDGEECQI 61

[Close]

BLAST of Ras-related protein vs. Ensembl Medaka
Match: si:ch73-116o1.2 (muscle RAS oncogene homolog [Source:NCBI gene;Acc:101159234])

HSP 1 Score: 131.724 bits (330), Expect = 1.702e-38
Identity = 68/114 (59.65%), Postives = 90/114 (78.95%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + VLDTAGQ+ FSAMR+QYMR GDGFL++FS+TD+ SF+ V   ++ ILR KD+E FP+++V NKVDL   RKVT E+  E+A + N+ Y+ETSAK PP+NVD AF E+VR+IR
Sbjct:   63 LDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDREAFPMVLVANKVDLVHLRKVTAEQGHEMAAKHNITYIETSAKDPPMNVDKAFHELVRVIR 176

HSP 2 Score: 46.9802 bits (110), Expect = 1.702e-38
Identity = 18/31 (58.06%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            +FQ+ FV DYDPTIED+Y++  E DG+W  L
Sbjct:   33 FFQKIFVPDYDPTIEDSYLKHTEIDGQWAIL 63

[Close]

BLAST of Ras-related protein vs. Ensembl Medaka
Match: rras2 (RAS related 2 [Source:NCBI gene;Acc:101162668])

HSP 1 Score: 113.62 bits (283), Expect = 1.459e-30
Identity = 63/114 (55.26%), Postives = 87/114 (76.32%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ F AMR+QYMR G+GFL++FS+TDR SF+ +    + ILR KD++ FP+I+VGNK DL  +R+V +EE + LA++L V YME SAK   +NVD AF E+VR+IR
Sbjct:   62 LDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILVGNKADLEIQRQVNQEEGQNLARQLKVTYMEASAK-IRMNVDQAFHELVRVIR 174

[Close]

BLAST of Ras-related protein vs. Ensembl Medaka
Match: rras (ras-related protein R-Ras [Source:NCBI gene;Acc:101174431])

HSP 1 Score: 107.071 bits (266), Expect = 3.437e-28
Identity = 55/114 (48.25%), Postives = 84/114 (73.68%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ F AMR+QYMR G+GFL++F++ DR S+  V+  +  ILR KD+++FP+++VGNK DL ++R ++ E+A+  A+E  + YME SAK    NVD  FL++V +IR
Sbjct:   56 LDILDTAGQEEFGAMREQYMRSGEGFLLVFALNDRGSYHEVQKFHTQILRVKDRDDFPMLLVGNKADLEQQRVISSEDAQAFARENRIHYMEASAK-NRYNVDEVFLKLVHIIR 168

[Close]

BLAST of Ras-related protein vs. Ensembl Medaka
Match: kras (KRAS proto-oncogene, GTPase [Source:NCBI gene;Acc:100049322])

HSP 1 Score: 92.4337 bits (228), Expect = 1.615e-23
Identity = 53/114 (46.49%), Postives = 78/114 (68.42%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + +LDTAGQ+ +SAMR QYMR G+GFL +F+I +  SF+ + H  + I R KD E+ P+++VGNK DL   R V  ++A++LA+   + ++ETSAK     VD+AF  +VR IR
Sbjct:   53 LDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL-PTRTVDTKQAQDLARSFGIPFIETSAKTRQ-GVDDAFYTLVREIR 164

HSP 2 Score: 35.8094 bits (81), Expect = 1.615e-23
Identity = 18/37 (48.65%), Postives = 24/37 (64.86%), Query Frame = 1

Query:    4 FQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTGLVDML 114
             Q  FV++YDPTIED+Y +    DGE C    L+D+L
Sbjct:   24 IQNHFVDEYDPTIEDSYRKQVVIDGETC----LLDIL 56

[Close]

BLAST of Ras-related protein vs. Ensembl Medaka
Match: ENSORLT00000001678.2 (ras-related protein O-RAL [Source:NCBI gene;Acc:101156149])

HSP 1 Score: 93.5893 bits (231), Expect = 4.993e-23
Identity = 52/116 (44.83%), Postives = 78/116 (67.24%), Query Frame = 3

Query:  132 LNVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + + +LDTAGQ+ ++A+R  Y R G+GFL++FSIT+  SF       + ILR K++E  P+++VGNK DL + R++T E+A   A E  VQY+ETSAK    NVD  F +++R +R
Sbjct:   62 VQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITELESFTATSEFREQILRVKEEEAIPLLLVGNKSDLEDRRQITAEDAASKAGEWGVQYVETSAK-TRANVDKVFFDLMREVR 176

[Close]

BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000075044.1 (SMESG000075044.1)

HSP 1 Score: 193.356 bits (490), Expect = 1.148e-68
Identity = 112/117 (95.73%), Postives = 115/117 (98.29%), Query Frame = 3

Query:  129 LLNVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
              +++VLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLAEERKVTEEEAKELAKELNVQYMETSAKPPPVNVDNAFLEVVRLIR
Sbjct:   62 WCDLTVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLAEERKVTEEEAKELAKELNVQYMETSAKPPPVNVDNAFLEVVRLIR 178

HSP 2 Score: 73.1738 bits (178), Expect = 1.148e-68
Identity = 33/34 (97.06%), Postives = 33/34 (97.06%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTGL 102
            YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDLT L
Sbjct:   35 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTVL 68

HSP 3 Score: 33.4982 bits (75), Expect = 1.148e-68
Identity = 25/29 (86.21%), Postives = 27/29 (93.10%), Query Frame = 1

Query:  520 LAIYRRFAHAALANQXXXXXXXXXXCEIV 606
            + + RRFAHAALANQKSRKKSKKTKCEIV
Sbjct:  174 VRLIRRFAHAALANQKSRKKSKKTKCEIV 202

[Close]

BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000024796.1 (SMESG000024796.1)

HSP 1 Score: 114.39 bits (285), Expect = 1.512e-32
Identity = 58/115 (50.43%), Postives = 88/115 (76.52%), Query Frame = 3

Query:  135 NVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            N+ V DTAGQ+ F++MR+ Y R  +GFL++FS+T R SF++VR  ++  LR++D+++FP+++V NK DL   RKVT  E + LAKEL + Y+ETSAK PP+N+++AF ++VR IR
Sbjct:   52 NLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR 166

HSP 2 Score: 43.5134 bits (101), Expect = 1.512e-32
Identity = 17/31 (54.84%), Postives = 24/31 (77.42%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            + Q+ FVE++DPTIE TY ++ E DGEW +L
Sbjct:   23 FMQKIFVENHDPTIESTYYKNYEVDGEWSNL 53

[Close]

BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000017314.1 (SMESG000017314.1)

HSP 1 Score: 90.1225 bits (222), Expect = 7.223e-24
Identity = 51/113 (45.13%), Postives = 80/113 (70.80%), Query Frame = 3

Query:  138 VSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLI 476
            + +LDTAG + F+AMR  YM+ G GF++++SIT ++SF  +  L + ILR KD +N P+++VGNK DL ++R V +E+ + LA++ N  +METSAK   +NV+  F ++VR I
Sbjct:   53 LEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSSFNELEDLREQILRVKDTDNVPMVLVGNKCDLEDDRSVGKEQGQVLARKFNCSFMETSAK-NKINVNEIFYDLVRQI 164

HSP 2 Score: 38.5058 bits (88), Expect = 7.223e-24
Identity = 17/31 (54.84%), Postives = 20/31 (64.52%), Query Frame = 1

Query:    1 YFQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
            + Q  FVE YDPTIED+Y +  E DG  C L
Sbjct:   23 FVQGIFVEKYDPTIEDSYRKQVEVDGSQCML 53

[Close]

BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000075225.1 (SMESG000075225.1)

HSP 1 Score: 87.0409 bits (214), Expect = 4.234e-23
Identity = 49/113 (43.36%), Postives = 74/113 (65.49%), Query Frame = 3

Query:  132 LNVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVR 470
              + +LDTAGQ+ +SAMR QYMR G+GFL +F++ ++ SF+ + +    + R KD E  P+++VGNKVDL   R V +   K +A++ ++ Y+ETSAK     VD AF  +VR
Sbjct:   51 CQLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAVNNQKSFEEIPNYRDRVKRVKDAEEIPMVLVGNKVDL-ANRTVIKTTGKAMAEDFSIPYVETSAKTRE-GVDEAFYTLVR 161

HSP 2 Score: 38.891 bits (89), Expect = 4.234e-23
Identity = 17/30 (56.67%), Postives = 20/30 (66.67%), Query Frame = 1

Query:    4 FQRTFVEDYDPTIEDTYIQSKEFDGEWCDL 93
             Q  FVE+YDPTIED+Y +    DGE C L
Sbjct:   24 IQNHFVEEYDPTIEDSYRKQMMIDGETCQL 53

[Close]

BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000016219.1 (SMESG000016219.1)

HSP 1 Score: 91.6633 bits (226), Expect = 2.091e-22
Identity = 53/116 (45.69%), Postives = 75/116 (64.66%), Query Frame = 3

Query:  132 LNVSVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLXXXXXXXXXXXXXXXXXXNVQYMETSAKPPPVNVDNAFLEVVRLIR 479
            + + +LDTAGQ+ +  +R  Y R G+GF+ +FSITD  S +      + ILR K  EN P I+VGNK+DL  +  VT EEA+ELA + NV Y+ETSAK    NVD  + +++R I+
Sbjct:   59 VQIDILDTAGQEDYVGIRDHYFRTGEGFMCVFSITDHASLEAASEFREQILRVKSNENVPFILVGNKIDLRSQSVVTSEEARELANKWNVDYIETSAKTKE-NVDRVYFQLLRDIQ 173

The following BLAST results are available for this feature:

BLAST of Ras-related protein vs. Ensembl Human
BLAST of Ras-related protein vs. Ensembl Celegans
BLAST of Ras-related protein vs. Ensembl Fly
BLAST of Ras-related protein vs. Ensembl Zebrafish
BLAST of Ras-related protein vs. Ensembl Xenopus
BLAST of Ras-related protein vs. Ensembl Mouse
BLAST of Ras-related protein vs. UniProt/SwissProt
BLAST of Ras-related protein vs. TrEMBL
BLAST of Ras-related protein vs. Ensembl Cavefish
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
BLAST of Ras-related protein vs. Ensembl Yeast
BLAST of Ras-related protein vs. Ensembl Nematostella
BLAST of Ras-related protein vs. Ensembl Medaka
BLAST of Ras-related protein vs. Planmine SMEST

BLAST of Ras-related protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MRAS	8.235e-37	58.77	muscle RAS oncogene homolog [Source:HGNC Symbol;Ac...	[more]
MRAS	8.235e-37	58.77	muscle RAS oncogene homolog [Source:HGNC Symbol;Ac...	[more]
MRAS	8.235e-37	58.77	muscle RAS oncogene homolog [Source:HGNC Symbol;Ac...	[more]
RRAS2	7.647e-31	54.78	RAS related 2 [Source:HGNC Symbol;Acc:HGNC:17271]	[more]
RRAS2	1.372e-30	55.26	RAS related 2 [Source:HGNC Symbol;Acc:HGNC:17271]	[more]

BLAST of Ras-related protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ras-2	2.040e-34	58.04	GTP binding protein; R-RAS related [Source:UniPro...	[more]
ras-2	2.040e-34	58.04	GTP binding protein; R-RAS related [Source:UniPro...	[more]
ras-1	4.327e-32	53.85	GTP binding protein; R-RAS related; R-ras1 homolog...	[more]
let-60	1.033e-21	43.86	Ras protein let-60 [Source:UniProtKB/Swiss-Prot;A...	[more]
rap-1	3.939e-21	42.48	Ras-related protein Rap-1 [Source:UniProtKB/Swiss...	[more]

BLAST of Ras-related protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ras64B	7.681e-28	46.40	gene:FBgn0003206 transcript:FBtr0073212	[more]
Rap1	2.026e-23	46.90	gene:FBgn0004636 transcript:FBtr0303154	[more]
Rap1	2.026e-23	46.90	gene:FBgn0004636 transcript:FBtr0072867	[more]
Rap1	2.026e-23	46.90	gene:FBgn0004636 transcript:FBtr0332671	[more]
Rala	3.031e-23	45.69	gene:FBgn0015286 transcript:FBtr0070583	[more]

BLAST of Ras-related protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:ch73-116o1.2	6.960e-38	58.77	si:ch73-116o1.2 [Source:ZFIN;Acc:ZDB-GENE-110411-6...	[more]
MRAS	6.960e-38	58.77	si:ch73-116o1.2 [Source:ZFIN;Acc:ZDB-GENE-110411-6...	[more]
mras	7.435e-38	57.89	muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-G...	[more]
mras	7.454e-38	57.89	muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-G...	[more]
rras2	5.265e-31	55.65	RAS related 2 [Source:ZFIN;Acc:ZDB-GENE-050417-352...	[more]

BLAST of Ras-related protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
thbs3	1.084e-37	59.65	thrombospondin 3 [Source:Xenbase;Acc:XB-GENE-57619...	[more]
tle1	2.007e-28	53.51	transducin like enhancer of split 1 [Source:Xenbas...	[more]
rpp38	1.350e-23	47.41	ribonuclease P/MRP 38kDa subunit [Source:Xenbase;A...	[more]
krasl	2.040e-23	46.49	Kirsten rat sarcoma viral oncogene homolog like [S...	[more]
krasl	9.036e-23	45.61	Kirsten rat sarcoma viral oncogene homolog like [S...	[more]

BLAST of Ras-related protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mras	3.452e-36	57.89	muscle and microspikes RAS [Source:MGI Symbol;Acc:...	[more]
Mras	3.452e-36	57.89	muscle and microspikes RAS [Source:MGI Symbol;Acc:...	[more]
Mras	3.452e-36	57.89	muscle and microspikes RAS [Source:MGI Symbol;Acc:...	[more]
Rras2	1.696e-30	54.78	related RAS viral (r-ras) oncogene 2 [Source:MGI S...	[more]
Rras	4.226e-28	49.12	related RAS viral (r-ras) oncogene [Source:MGI Sym...	[more]

BLAST of Ras-related protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O14807\|RASM_HUMAN	3.485e-36	58.77	Ras-related protein M-Ras OS=Homo sapiens OX=9606 ...	[more]
sp\|O08989\|RASM_MOUSE	2.008e-35	57.89	Ras-related protein M-Ras OS=Mus musculus OX=10090...	[more]
sp\|P97538\|RASM_RAT	2.145e-35	57.89	Ras-related protein M-Ras OS=Rattus norvegicus OX=...	[more]
sp\|P62071\|RRAS2_MOUSE	1.186e-29	54.78	Ras-related protein R-Ras2 OS=Mus musculus OX=1009...	[more]
sp\|P62070\|RRAS2_HUMAN	1.186e-29	54.78	Ras-related protein R-Ras2 OS=Homo sapiens OX=9606...	[more]

BLAST of Ras-related protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
R7U636	1.576e-38	63.16	Uncharacterized protein OS=Capitella teleta OX=283...	[more]
A0A210Q323	4.147e-38	58.77	Ras-related protein M-Ras OS=Mizuhopecten yessoens...	[more]
A0A1S3JDF1	1.013e-37	60.53	ras-related protein M-Ras-like OS=Lingula unguis O...	[more]
A0A1S3JBY1	1.128e-37	60.53	ras-related protein M-Ras-like isoform X1 OS=Lingu...	[more]
A0A212FEK5	1.342e-37	59.65	Ras-related protein M-Ras OS=Danaus plexippus plex...	[more]

BLAST of Ras-related protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:ch73-116o1.2	6.979e-38	57.89	muscle RAS oncogene homolog [Source:HGNC Symbol;Ac...	[more]
mras	7.900e-38	57.89	ras-related protein M-Ras [Source:NCBI gene;Acc:10...	[more]
rras2	7.007e-31	53.91	RAS related 2 [Source:NCBI gene;Acc:103027563]	[more]
rras	5.333e-29	51.75	RAS related [Source:ZFIN;Acc:ZDB-GENE-041010-217]	[more]
kras	1.334e-23	46.49	GTPase KRas [Source:NCBI gene;Acc:103038241]	[more]

BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000005561.1	2.619e-38	55.26	pep scaffold:Pmarinus_7.0:GL481089:12431:17765:1 g...	[more]
mras	2.965e-38	56.25	muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-G...	[more]
ENSPMAT00000000518.1	3.497e-38	56.14	pep scaffold:Pmarinus_7.0:GL479781:11597:21619:-1 ...	[more]
hrasb	2.621e-22	44.74	HRas proto-oncogene, GTPase b [Source:ZFIN;Acc:ZDB...	[more]
ralba	3.092e-21	43.10	v-ral simian leukemia viral oncogene homolog Ba (r...	[more]

BLAST of Ras-related protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
RAS1	9.143e-28	52.68	GTPase involved in G-protein signaling in adenylat...	[more]
RAS2	4.180e-25	46.43	GTP-binding protein; regulates nitrogen starvation...	[more]
RSR1	3.167e-16	40.17	GTP-binding protein of the Ras superfamily; requir...	[more]
GSP1	7.210e-11	31.19	Ran GTPase; GTP binding protein (mammalian Ranp ho...	[more]
GSP2	8.437e-11	31.19	GTP binding protein (mammalian Ranp homolog); invo...	[more]

BLAST of Ras-related protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO39171	2.386e-33	53.28	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32914	2.094e-23	47.37	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39047	6.558e-22	42.98	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36396	1.915e-21	45.61	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45827	2.644e-21	44.83	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Ras-related protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:ch73-116o1.2	1.702e-38	59.65	muscle RAS oncogene homolog [Source:NCBI gene;Acc:...	[more]
rras2	1.459e-30	55.26	RAS related 2 [Source:NCBI gene;Acc:101162668]	[more]
rras	3.437e-28	48.25	ras-related protein R-Ras [Source:NCBI gene;Acc:10...	[more]
kras	1.615e-23	46.49	KRAS proto-oncogene, GTPase [Source:NCBI gene;Acc:...	[more]
ENSORLT00000001678.2	4.993e-23	44.83	ras-related protein O-RAL [Source:NCBI gene;Acc:10...	[more]

BLAST of Ras-related protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000075044.1	1.148e-68	95.73	SMESG000075044.1	[more]
SMESG000024796.1	1.512e-32	50.43	SMESG000024796.1	[more]
SMESG000017314.1	7.223e-24	45.13	SMESG000017314.1	[more]
SMESG000075225.1	4.234e-23	43.36	SMESG000075225.1	[more]
SMESG000016219.1	2.091e-22	45.69	SMESG000016219.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30024514 ID=SMED30024514|Name=Ras-related protein|organism=Schmidtea mediterranea sexual|type=transcript|length=781bp
TACTTTCAACGGACATTTGTTGAAGATTATGACCCTACAATCGAAGATAC
ATATATTCAAAGCAAAGAATTCGATGGAGAATGGTGTGACCTTACTGGTT
TGGTAGATATGTTGCGGCGCTGAAGTAGTTATTAAATGTTTCAGTGTTGG
ACACTGCTGGTCAAGATTCATTCAGTGCAATGCGTCAACAGTATATGCGG
AAAGGTGACGGATTTCTAGTCATGTTTTCAATTACTGATCGAAACAGTTT
CCAAATGGTTAGACACCTTTATAAAGATATTCTCAGAACGAAAGACAAAG
AAAATTTCCCGGTTATCATTGTTGGAAACAAAGTCGATTTAGCGGAAGAA
AGAAAAGTCACAGAAGAGGAAGCGAAAGAATTGGCAAAGGAATTGAACGT
TCAATATATGGAAACGAGTGCCAAGCCACCGCCGGTAAATGTCGATAATG
CATTCTTGGAAGTTGTCAGATTAATCAGGTTCATTTTAATTAGCATTAAG
ATTTTGGCAGAAACATTATCTAGCTATTTACAGACGCTTTGCGCATGCCG
CACTCGCCAATCAGAAATCGAGAAAAAAATCGAAAAAAACAAAATGTGAA
ATAGTTTGAAGATTTTTGAGATTTTTCATTGAATCTCTTAGAATTATTCT
CGATTGTTTTGTTTTTTGGATTTTATATGCAGGGGATTATTGTCTATGAA
TATATTTTAATACACTTTTCCTTTAATTGTCATATTTTCTGTTTAGATTT
GATTGGTTCTTGTATGCAGATCATAATTAAT

protein sequence of SMED30024514-orf-1

>SMED30024514-orf-1 ID=SMED30024514-orf-1|Name=SMED30024514-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=140bp
MRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGN
KVDLAEERKVTEEEAKELAKELNVQYMETSAKPPPVNVDNAFLEVVRLIR
FILISIKILAETLSSYLQTLCACRTRQSEIEKKIEKNKM*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0000166	nucleotide binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000418	head
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR027417	P-loop_NTPase
IPR001806	Small_GTPase
IPR020849	Small_GTPase_Ras-type

Vocabulary: **biological process**
Term	Definition
GO:0007264	small GTPase mediated signal transduction
GO:0007165	signal transduction

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0005622	intracellular

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 51..82
None	No IPR available	SMART	SM00173	ras_sub_4	coord: 1..102 e-value: 6.5E-21 score: 85.5
None	No IPR available	SMART	SM00175	rab_sub_5	coord: 1..102 e-value: 6.3E-9 score: 1.8
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 1..102 e-value: 2.4E-34 score: 120.4
None	No IPR available	PANTHER	PTHR24070:SF268	RAS-RELATED PROTEIN M-RAS	coord: 1..101
IPR001806	Small GTPase	PFAM	PF00071	Ras	coord: 1..99 e-value: 1.6E-28 score: 99.3
IPR020849	Small GTPase superfamily, Ras-type	PANTHER	PTHR24070	FAMILY NOT NAMED	coord: 1..101
IPR020849	Small GTPase superfamily, Ras-type	PROSITE	PS51421	RAS	coord: 1..139 score: 22.826
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 1..111