TRMT1-like

Overview
NameTRMT1-like
Smed IDSMED30024492
Length (bp)1417
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TRMT1-like (SMED30024492) t-SNE clustered cells

Violin plots show distribution of expression levels for TRMT1-like (SMED30024492) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TRMT1-like (SMED30024492) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TRMT1-like (SMED30024492) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30024492

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30024492SMESG000005888.1 SmedASXL_014787SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30024492SMESG000005888.1 SmedASXL_014787SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30024492SMESG000005888.1 dd_Smed_v4_9064_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of TRMT1-like vs. Ensembl Human
Match: TRMT1L (tRNA methyltransferase 1 like [Source:HGNC Symbol;Acc:HGNC:16782])

HSP 1 Score: 259.225 bits (661), Expect = 5.291e-78
Identity = 162/464 (34.91%), Postives = 254/464 (54.74%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLK-DDINEYN----NSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEI-----TAFKVECES-VNERPD----------------------------------------FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E + ++     Y  P+    Y NPK+ +NR+L+F  L A       P+ECLDAF A+G+  LQW K+L     VT  D+ ++S+  I+ NC +N + VV ++    K DDI E       +I V K + NV+MHL+SFDFIH+DPFG++  YLDSAF+N+RN GI+ +TSTDI+SL  +  +   R+YG  +++TEY KELA R V+A  AR+AA+CNKG +V+ +V   +++ + + + RG + A++T  K+  L+HC+ CEER +     +    +PY   L CNCH +  GKT ++LGP W+ SL +   +++++  E+  H   + Q++++ +  E      + F +   S VN++ +                                         E P FYY +   ++ G   PK +K + ++   GF  SRT FDP  +RT+A L Q K I+ K
Sbjct:  231 EADTDVQVCPNYSIPQKTDSYFNPKMKLNRQLIFCTLAAL-AEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQENCHLNKLKVVVDSKEKEKSDDILEEGEKNLGNIKVTKMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNIRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVE-ENPYRQ-LPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRML-FESLHHGLDDIQTLIKTLIFESECTPQSQFSIHASSNVNKQEENGVFIKTTDDTTTDNYIAQGKRKSNEMITNLGKKQKTDVSTEHPPFYYNIHRHSIKGMNMPKLKKFLCYLSQAGFRVSRTHFDPMGVRTDAPLMQFKSILLK 690
[Close]
BLAST of TRMT1-like vs. Ensembl Human
Match: TRMT1L (tRNA methyltransferase 1 like [Source:HGNC Symbol;Acc:HGNC:16782])

HSP 1 Score: 125.946 bits (315), Expect = 4.153e-33
Identity = 75/197 (38.07%), Postives = 125/197 (63.45%), Query Frame = 3 
Query:  552 YLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVEC 1142
            YLDSAF+N+RN GI+ +TSTDI+SL  +  +   R+YG  +++TEY KELA R V+A  AR+AA+CNKG +V+ +V   +++ + + + RG + A++T  K+  L+HC+ CEER +     +    +PY   L CNCH +  GKT ++LGP W+ SL +   +++++  E+  H   + Q++++ +      F+ EC
Sbjct:    5 YLDSAFRNIRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVE-ENPYRQ-LPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRML-FESLHHGLDDIQTLIKTL-----IFESEC 193
[Close]
BLAST of TRMT1-like vs. Ensembl Human
Match: TRMT1 (tRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:25980])

HSP 1 Score: 80.1073 bits (196), Expect = 2.836e-15
Identity = 73/317 (23.03%), Postives = 139/317 (43.85%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHL-----KSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKV-ILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRIC--------EERAWYPSDKL------APIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKII-----NGENFQHRSKEFQSIMRLIYGEI 1121
            E  +  L+  +ASGL ++++   +P    V A D    +++ IR N ++ND+  +                 +   +++  ++M+      + FD I +DP+GS + +LD+A + +   G+L +T TD+A L   +  T    YGA  LK+    E+A+R V+  +    A C + F V +LS++   Y+ + + +  G +    +  K + +  C  C         + +  PS +        P V P     +C       G+     GP W   + D D V +++     N   F H S+  + ++ +I  E+
Sbjct:  151 EEGLHVLEGLAASGLRSIRFALEVPGLRSVVANDASTRAVDLIRRNVQLNDVAHL-----------------VQPSQADARMLMYQHQRVSERFDVIDLDPYGSPATFLDAAVQAVSEGGLLCVTCTDMAVLAGNSGETCYSKYGAMALKSRACHEMALRIVLH-SLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASKQALVFQCVGCGAFHLQRLGKASGVPSGRAKFSAACGPPVTP-----ECE----HCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRF-HTSERIRGVLSVITEEL 439
[Close]
BLAST of TRMT1-like vs. Ensembl Human
Match: TRMT1 (tRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:25980])

HSP 1 Score: 80.1073 bits (196), Expect = 2.836e-15
Identity = 73/317 (23.03%), Postives = 139/317 (43.85%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHL-----KSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKV-ILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRIC--------EERAWYPSDKL------APIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKII-----NGENFQHRSKEFQSIMRLIYGEI 1121
            E  +  L+  +ASGL ++++   +P    V A D    +++ IR N ++ND+  +                 +   +++  ++M+      + FD I +DP+GS + +LD+A + +   G+L +T TD+A L   +  T    YGA  LK+    E+A+R V+  +    A C + F V +LS++   Y+ + + +  G +    +  K + +  C  C         + +  PS +        P V P     +C       G+     GP W   + D D V +++     N   F H S+  + ++ +I  E+
Sbjct:  151 EEGLHVLEGLAASGLRSIRFALEVPGLRSVVANDASTRAVDLIRRNVQLNDVAHL-----------------VQPSQADARMLMYQHQRVSERFDVIDLDPYGSPATFLDAAVQAVSEGGLLCVTCTDMAVLAGNSGETCYSKYGAMALKSRACHEMALRIVLH-SLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASKQALVFQCVGCGAFHLQRLGKASGVPSGRAKFSAACGPPVTP-----ECE----HCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRF-HTSERIRGVLSVITEEL 439
[Close]
BLAST of TRMT1-like vs. Ensembl Human
Match: TRMT1 (tRNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:25980])

HSP 1 Score: 80.1073 bits (196), Expect = 2.836e-15
Identity = 73/317 (23.03%), Postives = 139/317 (43.85%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHL-----KSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKV-ILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRIC--------EERAWYPSDKL------APIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKII-----NGENFQHRSKEFQSIMRLIYGEI 1121
            E  +  L+  +ASGL ++++   +P    V A D    +++ IR N ++ND+  +                 +   +++  ++M+      + FD I +DP+GS + +LD+A + +   G+L +T TD+A L   +  T    YGA  LK+    E+A+R V+  +    A C + F V +LS++   Y+ + + +  G +    +  K + +  C  C         + +  PS +        P V P     +C       G+     GP W   + D D V +++     N   F H S+  + ++ +I  E+
Sbjct:  151 EEGLHVLEGLAASGLRSIRFALEVPGLRSVVANDASTRAVDLIRRNVQLNDVAHL-----------------VQPSQADARMLMYQHQRVSERFDVIDLDPYGSPATFLDAAVQAVSEGGLLCVTCTDMAVLAGNSGETCYSKYGAMALKSRACHEMALRIVLH-SLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASKQALVFQCVGCGAFHLQRLGKASGVPSGRAKFSAACGPPVTP-----ECE----HCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRF-HTSERIRGVLSVITEEL 439
[Close]
BLAST of TRMT1-like vs. Ensembl Celegans
Match: trm-1 (tRNA (guanine(26)-N(2))-dimethyltransferase [Source:UniProtKB/Swiss-Prot;Acc:Q23270])

HSP 1 Score: 90.8929 bits (224), Expect = 2.913e-19
Identity = 100/444 (22.52%), Postives = 183/444 (41.22%), Query Frame = 3 
Query:  171 VYLNPKLSVNRELVFEVLNAFCG-------------SSENP--------------VECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINE--YNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICE--------------ERAWY--PSDKLAPIVDPYANLLQC--NCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMN--VGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYKMI 1355
            V+ NP    NR+L   VL  F               + E P              +  LDA SASGL AL++ K +P    + A D  D+++  I+ N K+N +           +DI E  + +++  +  +  +    K F  + +DP+G+ S +LDSA + + + GIL++T TD+A L    P      Y A   + +   E+ +R ++     +A +  +  + ++S++   Y+ + + +  G+  A  +  KV  +L C  C               +++ Y  P+ + + I  P    + C    H+         +GP +   +     V  ++        ++   +  RL  G +T    E + V           YY    M   V    PK + V + I + GF  S +  +P AI+TNA +  + + IY+ +
Sbjct:   37 VFYNPVQEFNRDLTVTVLRQFSADHQKWAEEQKQLKTEEEPPKKKNKLAINEDGKIRILDALSASGLRALRFSKEVPNVGFIMANDFSDNAVASIQENVKLNGV-----------EDIVEAHFGDAVMTMMEHRGID---KRFHAVDLDPYGTASTFLDSAVQCVADRGILMVTCTDMAVLCGNTPEACYNKYDAVTTRMKCCHEVGLRILLRAIDSAANRYTRYIEPLVSISVDFYVRVFVRVHTGAFQAKQSGTKVGTVLVCSGCHSMEPLVLLKRGEGNQQSKYSIPTVRHS-ISGPGNRCIHCLLPLHQ---------IGPIYLAPIHSKPFVTSLLERLKSTPEAERLGTHGRL-QGVLTMVNEELDDV----------LYYEHNQMANVVKVSVPKSQSVRSAILNAGFKVSGSHCNPRAIKTNAPMHLLWD-IYRQV 444
[Close]
BLAST of TRMT1-like vs. Ensembl Fly
Match: CG6388 (gene:FBgn0032430 transcript:FBtr0080367)

HSP 1 Score: 77.411 bits (189), Expect = 9.210e-15
Identity = 69/318 (21.70%), Postives = 134/318 (42.14%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHL-----KSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQ-----------CNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESV 1151
            E+ +  L+A +A+GL ++++ + +     + A D+   ++  I  N + N +  +                 I    S+   +M+L     K FD + +DP+G  + +LD A + L + G+L++T+TD+A L    P      YG+  L+ +   E+A+R ++      A +  K  + +LS++   YI I + +  G +    ++ K S +  C  CE     P     P  +P A   Q            N      G      GP W+  + + + V+ ++     Q  + +     R I G ++  + E + V
Sbjct:   98 EDGLRILEALAATGLRSIRYAQEIAGVRQIVANDLSRQAVASINTNIRHNKVEEL-----------------IEPSHSDAMTLMYLSTQPEKRFDAVDLDPYGCPNRFLDGAMQCLVDGGLLLVTATDMAVLAGNAPEACYVKYGSVPLRMKCCHEMALRILLHCIESHANRYGKYIEPLLSISADFYIRIFVRVYVGQAQCKLSMSKQSWIYQCTGCETFTLQPLGITKP--NPTAGNPQQLKFGIPTGPAVNSQCEHCGHRHHLGGPIWSAPIHNPEFVQDLLTA--VQETTLQSLGTQRRIVGVLSMVQEELQDV 394
[Close]
BLAST of TRMT1-like vs. Ensembl Zebrafish
Match: trmt1l (tRNA methyltransferase 1-like [Source:ZFIN;Acc:ZDB-GENE-041014-189])

HSP 1 Score: 282.337 bits (721), Expect = 7.132e-88
Identity = 164/469 (34.97%), Postives = 254/469 (54.16%), Query Frame = 3 
Query:   99 IMLYFENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNN---SITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGE--ITAFK-------------VEC-------ESVNE------------------------RPD--FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            IM     NV +L +  + +P+    Y + K+  NR+LVF  L A      NP+ECLDAF A+G+  LQW K+L     VT  D+ +  ++ I+ NC +N I V  N      D   +  +   S+ V+K + NVIMHL+ FD+IH+DPFG+   YLD+AF+N+RN GI+ +TSTD  SL +++ N  LR+YG ++++TEY +ELA R V+A  AR+AA+CNKG +V+L+V   +++ + + + RG + A+++  K+ +LLHC+ CEER +     +  + +     L C CH +  GKT V+LGP W G L +   + +++     QH  ++ Q +++ +  E   T  K             VEC       + V E                        +PD   E P+FYY +   ++ G   PK  K + ++   GF  SRT FDP  +RT+ATL Q KE++ K
Sbjct:  158 IMKELGTNVQLLPN--HTTPQKTDTYFSRKMKTNRQLVFCSL-AVLAEERNPLECLDAFGATGIMGLQWAKHLRNSVKVTINDINEACVKMIKENCHLNHIRVEGNRTGRQLDGAGDPESPIASVEVVKMDANVIMHLRPFDYIHLDPFGTAINYLDAAFRNVRNLGIVSVTSTDTGSLYSKSLNVTLRHYGCQIVRTEYYRELAARMVLASVARAAARCNKGIEVLLAVALEHFVLVVVRVLRGPTQADESAKKLRQLLHCQWCEERVFLKPGSM--VEENLYRQLPCQCHGSMPGKTAVELGPLWGGPLFNTGFLRRMLVAA-VQHNMEDIQPLVKTLICEADCTTLKPFPVPGHSALSNQVECGVVIKTLQKVEEADTSDQSGKRKTTGDDGGNVLKKVKPDTSLEHPAFYYSIHRHSIRGMNMPKLNKFLQYLTEAGFRVSRTHFDPTGVRTDATLAQFKEVLTK 620
[Close]
BLAST of TRMT1-like vs. Ensembl Zebrafish
Match: trmt1l (tRNA methyltransferase 1-like [Source:ZFIN;Acc:ZDB-GENE-041014-189])

HSP 1 Score: 283.493 bits (724), Expect = 1.098e-87
Identity = 164/469 (34.97%), Postives = 254/469 (54.16%), Query Frame = 3 
Query:   99 IMLYFENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNN---SITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGE--ITAFK-------------VEC-------ESVNE------------------------RPD--FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            IM     NV +L +  + +P+    Y + K+  NR+LVF  L A      NP+ECLDAF A+G+  LQW K+L     VT  D+ +  ++ I+ NC +N I V  N      D   +  +   S+ V+K + NVIMHL+ FD+IH+DPFG+   YLD+AF+N+RN GI+ +TSTD  SL +++ N  LR+YG ++++TEY +ELA R V+A  AR+AA+CNKG +V+L+V   +++ + + + RG + A+++  K+ +LLHC+ CEER +     +  + +     L C CH +  GKT V+LGP W G L +   + +++     QH  ++ Q +++ +  E   T  K             VEC       + V E                        +PD   E P+FYY +   ++ G   PK  K + ++   GF  SRT FDP  +RT+ATL Q KE++ K
Sbjct:  209 IMKELGTNVQLLPN--HTTPQKTDTYFSRKMKTNRQLVFCSL-AVLAEERNPLECLDAFGATGIMGLQWAKHLRNSVKVTINDINEACVKMIKENCHLNHIRVEGNRTGRQLDGAGDPESPIASVEVVKMDANVIMHLRPFDYIHLDPFGTAINYLDAAFRNVRNLGIVSVTSTDTGSLYSKSLNVTLRHYGCQIVRTEYYRELAARMVLASVARAAARCNKGIEVLLAVALEHFVLVVVRVLRGPTQADESAKKLRQLLHCQWCEERVFLKPGSM--VEENLYRQLPCQCHGSMPGKTAVELGPLWGGPLFNTGFLRRMLVAA-VQHNMEDIQPLVKTLICEADCTTLKPFPVPGHSALSNQVECGVVIKTLQKVEEADTSDQSGKRKTTGDDGGNVLKKVKPDTSLEHPAFYYSIHRHSIRGMNMPKLNKFLQYLTEAGFRVSRTHFDPTGVRTDATLAQFKEVLTK 671
[Close]
BLAST of TRMT1-like vs. Ensembl Zebrafish
Match: trmt1 (tRNA methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-060810-40])

HSP 1 Score: 91.6633 bits (226), Expect = 3.066e-19
Identity = 88/385 (22.86%), Postives = 172/385 (44.68%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHC-------------RICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKI---INGENFQHR-SKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMN--VGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEII 1343
            E  +  L+  +ASGL ++++   +P    +TA D    +   I  N + N+   VT+ +   + D      S+ + ++        + +D I +DP+GS SP+LDSA + +   G+L +T TD+A +   +  T    YG+  +K++Y  E+A+R ++    + AA   +  + +LSV+   YI + + +K G     ++  K + + +C             RI + +    S    P V P       NC     G+     GP W   L D + V+K+   ++G   + R SK  + ++ ++  E+                ++P  YY L +++  V    P   +  + +   G+  S +    +A++T+A  G + +I+
Sbjct:  194 EQGLRVLEGLAASGLRSVRFALEVPGLKSITANDYSAKAAALIARNAQHNN---VTHILQASQRDA-----SMVMYEARGRK----ERYDVIDLDPYGSPSPFLDSAVQAVSEGGLLCITCTDMAVMAGNSGETCYSKYGSVSIKSKYCHEMALRIILHSLDQRAAVYQRYIEPLLSVSVDFYIRVFVRVKTGQVVVKNSASKQALVYNCVGCGAFHLQRMGKRINQGKHMKYSAATGPPVGP-------NCEH--CGQRHQLGGPAWAEPLHDINFVQKVLGAVSGNPTRFRTSKRIEGMLSMVTEELQ---------------DVP-LYYTLDHLSSTVHRSTPPMMQFRSALLHAGYRVSFSHACKNAVKTDAPAGVLWDIM 541
[Close]
BLAST of TRMT1-like vs. Ensembl Xenopus
Match: ca2 (carbonic anhydrase 2 [Source:Xenbase;Acc:XB-GENE-484348])

HSP 1 Score: 273.478 bits (698), Expect = 8.644e-85
Identity = 157/437 (35.93%), Postives = 252/437 (57.67%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYN-------NSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVEC---ESVNERPD--------------FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E N ++  +  +++P+    + NPK+ VNR+L+F  L A      N +ECLDAF ++G+  LQW K+L     VT  D+ + S+  IR NC +N++ V+TN     KDD +E N       +++ V + + NV+MHL++FDFIH+DPFG++  YLD+AF+N+RN GI+ +TSTD  SL  ++PN   R+YG  +++TEY +ELA R ++A  AR+AA+ NKG  V+LSV   +++ + + + RG + A++++ K+  L+HC+ CEER +     +    +PY N L C+C E+  G + V LGP W+GSL +   + +++  E  +H   +   +++ +  E      EC   +  + +P                E P FYY +   ++ G   PK  K + ++   GF  SRT FDP  IRTNA+L   K I+ K
Sbjct:  129 ELNTHVQVAPNFKTPQKTDTFFNPKMKVNRQLIFCAL-AVLAKERNALECLDAFGSTGIMGLQWAKHLGKSVKVTINDISEGSVAMIRENCLLNNLKVLTNK----KDDEDEENEVGEASDDAVEVTQLDANVLMHLRAFDFIHLDPFGTSVNYLDAAFRNVRNLGIVSVTSTDTGSLFAKSPNVTKRHYGCHIVRTEYYRELAARIILATLARAAARYNKGIDVLLSVAVEHFVLVVVRVLRGPTQADESIHKIHSLIHCQWCEERIFQKEGNMVQ-ENPYKN-LPCDCQESMQGNSAVVLGPMWSGSLFNMGFLRRMMI-EAVEHEMDDIHPLLKTLLCE-----AECTLQKQFSTQPSQTDNGKSSRINEALVEHPPFYYSIHRHSIRGLNIPKLNKFLQYLAEAGFKVSRTHFDPTGIRTNASLATFKSILQK 552
[Close]
BLAST of TRMT1-like vs. Ensembl Xenopus
Match: ca2 (carbonic anhydrase 2 [Source:Xenbase;Acc:XB-GENE-484348])

HSP 1 Score: 264.618 bits (675), Expect = 6.192e-81
Identity = 158/467 (33.83%), Postives = 253/467 (54.18%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYN-------NSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVEC---ESVNERPDF--------------------------------------------EIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E N ++  +  +++P+    + NPK+ VNR+L+F  L A      N +ECLDAF ++G+  LQW K+L     VT  D+ + S+  IR NC +N++ V+TN     KDD +E N       +++ V + + NV+MHL++FDFIH+DPFG++  YLD+AF+N+RN GI+ +TSTD  SL  ++PN   R+YG  +++TEY +ELA R ++A  AR+AA+ NKG  V+LSV   +++ + + + RG + A++++ K+  L+HC+ CEER +     +    +PY N L C+C E+  G + V LGP W+GSL +   + +++  E  +H   +   +++ +  E      EC   +  + +P F                                            E P FYY +   ++ G   PK  K + ++   GF  SRT FDP  IRTNA+L   K I+ K
Sbjct:  111 ELNTHVQVAPNFKTPQKTDTFFNPKMKVNRQLIFCAL-AVLAKERNALECLDAFGSTGIMGLQWAKHLGKSVKVTINDISEGSVAMIRENCLLNNLKVLTNK----KDDEDEENEVGEASDDAVEVTQLDANVLMHLRAFDFIHLDPFGTSVNYLDAAFRNVRNLGIVSVTSTDTGSLFAKSPNVTKRHYGCHIVRTEYYRELAARIILATLARAAARYNKGIDVLLSVAVEHFVLVVVRVLRGPTQADESIHKIHSLIHCQWCEERIFQKEGNMVQ-ENPYKN-LPCDCQESMQGNSAVVLGPMWSGSLFNMGFLRRMMI-EAVEHEMDDIHPLLKTLLCE-----AECTLQKQFSTQPTFLSTEESGVVIKFSDPSDCSTDPGKRKRCDMSKNISKRLRNEALVEHPPFYYSIHRHSIRGLNIPKLNKFLQYLAEAGFKVSRTHFDPTGIRTNASLATFKSILQK 564
[Close]
BLAST of TRMT1-like vs. Ensembl Xenopus
Match: ca2 (carbonic anhydrase 2 [Source:Xenbase;Acc:XB-GENE-484348])

HSP 1 Score: 263.077 bits (671), Expect = 1.413e-80
Identity = 160/462 (34.63%), Postives = 254/462 (54.98%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYN-------NSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMR--LIYGEITAFK-----------------------VECES---VNERPDF--------------EIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E N ++  +  +++P+    + NPK+ VNR+L+F  L A      N +ECLDAF ++G+  LQW K+L     VT  D+ + S+  IR NC +N++ V+TN     KDD +E N       +++ V + + NV+MHL++FDFIH+DPFG++  YLD+AF+N+RN GI+ +TSTD  SL  ++PN   R+YG  +++TEY +ELA R ++A  AR+AA+ NKG  V+LSV   +++ + + + RG + A++++ K+  L+HC+ CEER +     +    +PY N L C+C E+  G + V LGP W+GSL +   + +++  E  +H   +   +++  L   E T  K                        +C +     +R D               E P FYY +   ++ G   PK  K + ++   GF  SRT FDP  IRTNA+L   K I+ K
Sbjct:  121 ELNTHVQVAPNFKTPQKTDTFFNPKMKVNRQLIFCAL-AVLAKERNALECLDAFGSTGIMGLQWAKHLGKSVKVTINDISEGSVAMIRENCLLNNLKVLTNK----KDDEDEENEVGEASDDAVEVTQLDANVLMHLRAFDFIHLDPFGTSVNYLDAAFRNVRNLGIVSVTSTDTGSLFAKSPNVTKRHYGCHIVRTEYYRELAARIILATLARAAARYNKGIDVLLSVAVEHFVLVVVRVLRGPTQADESIHKIHSLIHCQWCEERIFQKEGNMVQ-ENPYKN-LPCDCQESMQGNSAVVLGPMWSGSLFNMGFLRRMM-IEAVEHEMDDIHPLLKTLLCEAECTLQKQFSTQPSQTDNEESGVVIKFSDPSDCSTDPGKRKRCDMSKNISKRLRNEALVEHPPFYYSIHRHSIRGLNIPKLNKFLQYLAEAGFKVSRTHFDPTGIRTNASLATFKSILQK 574
[Close]
BLAST of TRMT1-like vs. Ensembl Xenopus
Match: ca2 (carbonic anhydrase 2 [Source:Xenbase;Acc:XB-GENE-484348])

HSP 1 Score: 263.462 bits (672), Expect = 1.862e-80
Identity = 160/462 (34.63%), Postives = 254/462 (54.98%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYN-------NSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMR--LIYGEITAFK-----------------------VECES---VNERPDF--------------EIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E N ++  +  +++P+    + NPK+ VNR+L+F  L A      N +ECLDAF ++G+  LQW K+L     VT  D+ + S+  IR NC +N++ V+TN     KDD +E N       +++ V + + NV+MHL++FDFIH+DPFG++  YLD+AF+N+RN GI+ +TSTD  SL  ++PN   R+YG  +++TEY +ELA R ++A  AR+AA+ NKG  V+LSV   +++ + + + RG + A++++ K+  L+HC+ CEER +     +    +PY N L C+C E+  G + V LGP W+GSL +   + +++  E  +H   +   +++  L   E T  K                        +C +     +R D               E P FYY +   ++ G   PK  K + ++   GF  SRT FDP  IRTNA+L   K I+ K
Sbjct:  146 ELNTHVQVAPNFKTPQKTDTFFNPKMKVNRQLIFCAL-AVLAKERNALECLDAFGSTGIMGLQWAKHLGKSVKVTINDISEGSVAMIRENCLLNNLKVLTNK----KDDEDEENEVGEASDDAVEVTQLDANVLMHLRAFDFIHLDPFGTSVNYLDAAFRNVRNLGIVSVTSTDTGSLFAKSPNVTKRHYGCHIVRTEYYRELAARIILATLARAAARYNKGIDVLLSVAVEHFVLVVVRVLRGPTQADESIHKIHSLIHCQWCEERIFQKEGNMVQ-ENPYKN-LPCDCQESMQGNSAVVLGPMWSGSLFNMGFLRRMMI-EAVEHEMDDIHPLLKTLLCEAECTLQKQFSTQPSQTDNEESGVVIKFSDPSDCSTDPGKRKRCDMSKNISKRLRNEALVEHPPFYYSIHRHSIRGLNIPKLNKFLQYLAEAGFKVSRTHFDPTGIRTNASLATFKSILQK 599
[Close]
BLAST of TRMT1-like vs. Ensembl Xenopus
Match: ca2 (carbonic anhydrase 2 [Source:Xenbase;Acc:XB-GENE-484348])

HSP 1 Score: 263.462 bits (672), Expect = 2.090e-80
Identity = 160/462 (34.63%), Postives = 254/462 (54.98%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYN-------NSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMR--LIYGEITAFK-----------------------VECES---VNERPDF--------------EIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E N ++  +  +++P+    + NPK+ VNR+L+F  L A      N +ECLDAF ++G+  LQW K+L     VT  D+ + S+  IR NC +N++ V+TN     KDD +E N       +++ V + + NV+MHL++FDFIH+DPFG++  YLD+AF+N+RN GI+ +TSTD  SL  ++PN   R+YG  +++TEY +ELA R ++A  AR+AA+ NKG  V+LSV   +++ + + + RG + A++++ K+  L+HC+ CEER +     +    +PY N L C+C E+  G + V LGP W+GSL +   + +++  E  +H   +   +++  L   E T  K                        +C +     +R D               E P FYY +   ++ G   PK  K + ++   GF  SRT FDP  IRTNA+L   K I+ K
Sbjct:  158 ELNTHVQVAPNFKTPQKTDTFFNPKMKVNRQLIFCAL-AVLAKERNALECLDAFGSTGIMGLQWAKHLGKSVKVTINDISEGSVAMIRENCLLNNLKVLTNK----KDDEDEENEVGEASDDAVEVTQLDANVLMHLRAFDFIHLDPFGTSVNYLDAAFRNVRNLGIVSVTSTDTGSLFAKSPNVTKRHYGCHIVRTEYYRELAARIILATLARAAARYNKGIDVLLSVAVEHFVLVVVRVLRGPTQADESIHKIHSLIHCQWCEERIFQKEGNMVQ-ENPYKN-LPCDCQESMQGNSAVVLGPMWSGSLFNMGFLRRMM-IEAVEHEMDDIHPLLKTLLCEAECTLQKQFSTQPSQTDNEESGVVIKFSDPSDCSTDPGKRKRCDMSKNISKRLRNEALVEHPPFYYSIHRHSIRGLNIPKLNKFLQYLAEAGFKVSRTHFDPTGIRTNASLATFKSILQK 611
[Close]
BLAST of TRMT1-like vs. Ensembl Mouse
Match: Trmt1l (tRNA methyltransferase 1 like [Source:MGI Symbol;Acc:MGI:1916185])

HSP 1 Score: 252.677 bits (644), Expect = 1.063e-75
Identity = 159/462 (34.42%), Postives = 249/462 (53.90%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNS---ITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMR-LIYGEITAFKVECES---------------VNERPDFEI------------------------------PSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E + +I     Y  P+    Y NPK+ +NR+++F  L A       P+ECLDAF A+G+  LQW K+L     VT  D+ ++S+  I+ NC +N + VV ++    + D  E + +   I V + + NV+MHL+SFDFIH+DPFG++  YLDSAF+N+RN GI+ +TSTDI+SL  +  +   R+YG  +++TEY KELA R V+A  AR+AA+CNKG +V+ +V   +++ + + + RG + A++T  K+  L+HC+ CEER +     +    +PY   L CNCH +  GKT ++LGP W+ SL +   +++++  E+  H   + Q +++ LI+      + +C +               V    D  I                              P FYY +   ++ G   PK +K +  +   GF  SRT FDP  IRT+A L Q K I+ K
Sbjct:  228 ETDTDIQVFPNYSIPQKTDSYFNPKMKLNRQIIFCTLAAL-AKERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEDDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVE-ENPYRQ-LPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRML-FESIHHGLDDIQPLIKTLIFESECTPQSQCSTHAPSNTNKQEENGVFVKTTDDTTIDIYSAQGKRKSNEMAINLAKKQKTDASTAHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLK 685
[Close]
BLAST of TRMT1-like vs. Ensembl Mouse
Match: Trmt1 (tRNA methyltransferase 1 [Source:MGI Symbol;Acc:MGI:1289155])

HSP 1 Score: 83.9593 bits (206), Expect = 1.096e-16
Identity = 88/383 (22.98%), Postives = 164/383 (42.82%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKS---FDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKV-ILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANL---LQCNCHETT----AGKTGVKLGPFWNGSLCDYDLVEKIINGENFQ----HRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMN--VGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEII 1343
            E  +  L+  +ASGL ++++   +P    V A D    ++E +  N ++N  GV      N  D             + + +  H K+   FD I +DP+GS +P+LD+A + + + G+L +T TD+A L   +  T    YGA  LK+    E+A+R V+  +    A C + + V +LS++   YI + + +  G +    +  K + +  C  C   A+Y         DP   +     C    T      G+     GP W   + D D V ++++         H S   Q ++ ++  E+             PD  +   YY L  ++  +    P+  ++ + +   GF  S +    +A++T+A    + +I+
Sbjct:  150 EEGLRVLEGLAASGLRSIRFALEVPGLQSVVANDASARAVELMHRNVELN--GVAHLVQPNQAD-------------ARMLMYQHQKAPERFDVIDLDPYGSPAPFLDAAVQAVSDGGLLCVTCTDMAVLAGNSGETCYSKYGAMALKSRACHEMALRIVLH-SLDLHANCYQRYIVPLLSISADFYIRVFVRVFTGQAKVKSSASKQALVFQCVGCG--AFYLQRLGKASGDPGGRIKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLDAVTTNPGRFHTSMRIQGVLSVVTEEL-------------PDVPL---YYTLDQLSSTIHCNTPRLLQLRSALLHAGFRVSLSHACKNAVKTDAPPEALWDIM 498
[Close]
BLAST of TRMT1-like vs. Ensembl Mouse
Match: Trmt1 (tRNA methyltransferase 1 [Source:MGI Symbol;Acc:MGI:1289155])

HSP 1 Score: 83.9593 bits (206), Expect = 1.096e-16
Identity = 88/383 (22.98%), Postives = 164/383 (42.82%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKS---FDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKV-ILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANL---LQCNCHETT----AGKTGVKLGPFWNGSLCDYDLVEKIINGENFQ----HRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMN--VGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEII 1343
            E  +  L+  +ASGL ++++   +P    V A D    ++E +  N ++N  GV      N  D             + + +  H K+   FD I +DP+GS +P+LD+A + + + G+L +T TD+A L   +  T    YGA  LK+    E+A+R V+  +    A C + + V +LS++   YI + + +  G +    +  K + +  C  C   A+Y         DP   +     C    T      G+     GP W   + D D V ++++         H S   Q ++ ++  E+             PD  +   YY L  ++  +    P+  ++ + +   GF  S +    +A++T+A    + +I+
Sbjct:  150 EEGLRVLEGLAASGLRSIRFALEVPGLQSVVANDASARAVELMHRNVELN--GVAHLVQPNQAD-------------ARMLMYQHQKAPERFDVIDLDPYGSPAPFLDAAVQAVSDGGLLCVTCTDMAVLAGNSGETCYSKYGAMALKSRACHEMALRIVLH-SLDLHANCYQRYIVPLLSISADFYIRVFVRVFTGQAKVKSSASKQALVFQCVGCG--AFYLQRLGKASGDPGGRIKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLDAVTTNPGRFHTSMRIQGVLSVVTEEL-------------PDVPL---YYTLDQLSSTIHCNTPRLLQLRSALLHAGFRVSLSHACKNAVKTDAPPEALWDIM 498
[Close]
BLAST of TRMT1-like vs. Ensembl Mouse
Match: Trmt1 (tRNA methyltransferase 1 [Source:MGI Symbol;Acc:MGI:1289155])

HSP 1 Score: 83.9593 bits (206), Expect = 1.156e-16
Identity = 88/383 (22.98%), Postives = 164/383 (42.82%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKS---FDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKV-ILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANL---LQCNCHETT----AGKTGVKLGPFWNGSLCDYDLVEKIINGENFQ----HRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMN--VGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEII 1343
            E  +  L+  +ASGL ++++   +P    V A D    ++E +  N ++N  GV      N  D             + + +  H K+   FD I +DP+GS +P+LD+A + + + G+L +T TD+A L   +  T    YGA  LK+    E+A+R V+  +    A C + + V +LS++   YI + + +  G +    +  K + +  C  C   A+Y         DP   +     C    T      G+     GP W   + D D V ++++         H S   Q ++ ++  E+             PD  +   YY L  ++  +    P+  ++ + +   GF  S +    +A++T+A    + +I+
Sbjct:  143 EEGLRVLEGLAASGLRSIRFALEVPGLQSVVANDASARAVELMHRNVELN--GVAHLVQPNQAD-------------ARMLMYQHQKAPERFDVIDLDPYGSPAPFLDAAVQAVSDGGLLCVTCTDMAVLAGNSGETCYSKYGAMALKSRACHEMALRIVLH-SLDLHANCYQRYIVPLLSISADFYIRVFVRVFTGQAKVKSSASKQALVFQCVGCG--AFYLQRLGKASGDPGGRIKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLDAVTTNPGRFHTSMRIQGVLSVVTEEL-------------PDVPL---YYTLDQLSSTIHCNTPRLLQLRSALLHAGFRVSLSHACKNAVKTDAPPEALWDIM 491
[Close]
BLAST of TRMT1-like vs. Ensembl Mouse
Match: Trmt1 (tRNA methyltransferase 1 [Source:MGI Symbol;Acc:MGI:1289155])

HSP 1 Score: 79.337 bits (194), Expect = 3.153e-15
Identity = 84/375 (22.40%), Postives = 155/375 (41.33%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKS---FDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQ----HRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMN--VGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEII 1343
            E  +  L+  +ASGL ++++   +P    V A D    ++E +  N ++N  GV      N  D             + + +  H K+   FD I +DP+GS +P+LD+A + + + G+L +T TD+A L   +  T    YGA  LK+    E+A+R V+      A    +    +LS++   YI + + +     F     +K S  +            S    P V P     +C       G+     GP W   + D D V ++++         H S   Q ++ ++  E+             PD  +   YY L  ++  +    P+  ++ + +   GF  S +    +A++T+A    + +I+
Sbjct:  150 EEGLRVLEGLAASGLRSIRFALEVPGLQSVVANDASARAVELMHRNVELN--GVAHLVQPNQAD-------------ARMLMYQHQKAPERFDVIDLDPYGSPAPFLDAAVQAVSDGGLLCVTCTDMAVLAGNSGETCYSKYGAMALKSRACHEMALRIVLHSLDLHANCYQRYIVPLLSISADFYIRVFVRV-----FTGQAKVKSSARIKF----------SAACGPPVTP-----ECE----HCGQRHQLGGPMWAEPIHDLDFVGRVLDAVTTNPGRFHTSMRIQGVLSVVTEEL-------------PDVPL---YYTLDQLSSTIHCNTPRLLQLRSALLHAGFRVSLSHACKNAVKTDAPPEALWDIM 469
[Close]
BLAST of TRMT1-like vs. UniProt/SwissProt
Match: sp|A5D7S3|TRM1L_BOVIN (TRMT1-like protein OS=Bos taurus OX=9913 GN=TRMT1L PE=2 SV=1)

HSP 1 Score: 259.61 bits (662), Expect = 1.981e-77
Identity = 160/462 (34.63%), Postives = 252/462 (54.55%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNL-KDDINEYN----NSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGE---ITAFKVECESVNERPD-----------------------------------------FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E + ++     Y  P+    Y NPK+ +NR+L+F  L A       P+ECLDAF A+G+  LQW K+L     VT  D+ ++S+  I+ NC +N + VV ++     ++DI E       +I V K + NV+MHL+SFDFIH+DPFG++  YLDSAF+N+RN GI+ +TSTDI+SL  +  +   R+YG  +++TEY KELA R V+A  AR+AA+CNKG +V+ +V   +++ + + + RG + A++T  K+  L+HC+ CEER +     +    +PY   L CNCH +  GKT ++LGP W+ SL +   ++++++ E+  H   + Q++++ +  E      F V   S   +P+                                          E P FYY +   ++ G   PK +K + ++   GF  SRT FDP  +RT+A L Q K I+ K
Sbjct:  237 EADTDVQVCPNYTVPQKTDSYFNPKMKLNRQLIFCTLAAL-AKERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQENCHLNKLKVVVDSKEKEEREDILEEGEENLGNIKVTKMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNIRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVE-ENPYRQ-LPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLS-ESLHHGLDDIQTLIKTLIFESECTPQFSVHAPSNLNKPEECGVFIKTTDDTTTDSHSAQGKRKSNETTANLVKRQKTDVNTEHPPFYYNIHRHSIKGMNMPKLKKFLCYLSQAGFRVSRTHFDPMGVRTDAPLMQFKSILLK 694
[Close]
BLAST of TRMT1-like vs. UniProt/SwissProt
Match: sp|Q7Z2T5|TRM1L_HUMAN (TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2)

HSP 1 Score: 259.225 bits (661), Expect = 2.541e-77
Identity = 162/464 (34.91%), Postives = 254/464 (54.74%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLK-DDINEYN----NSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEI-----TAFKVECES-VNERPD----------------------------------------FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E + ++     Y  P+    Y NPK+ +NR+L+F  L A       P+ECLDAF A+G+  LQW K+L     VT  D+ ++S+  I+ NC +N + VV ++    K DDI E       +I V K + NV+MHL+SFDFIH+DPFG++  YLDSAF+N+RN GI+ +TSTDI+SL  +  +   R+YG  +++TEY KELA R V+A  AR+AA+CNKG +V+ +V   +++ + + + RG + A++T  K+  L+HC+ CEER +     +    +PY   L CNCH +  GKT ++LGP W+ SL +   +++++  E+  H   + Q++++ +  E      + F +   S VN++ +                                         E P FYY +   ++ G   PK +K + ++   GF  SRT FDP  +RT+A L Q K I+ K
Sbjct:  231 EADTDVQVCPNYSIPQKTDSYFNPKMKLNRQLIFCTLAAL-AEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQENCHLNKLKVVVDSKEKEKSDDILEEGEKNLGNIKVTKMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNIRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVE-ENPYRQ-LPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRML-FESLHHGLDDIQTLIKTLIFESECTPQSQFSIHASSNVNKQEENGVFIKTTDDTTTDNYIAQGKRKSNEMITNLGKKQKTDVSTEHPPFYYNIHRHSIKGMNMPKLKKFLCYLSQAGFRVSRTHFDPMGVRTDAPLMQFKSILLK 690
[Close]
BLAST of TRMT1-like vs. UniProt/SwissProt
Match: sp|Q5R5T0|TRM1L_PONAB (TRMT1-like protein OS=Pongo abelii OX=9601 GN=TRMT1L PE=2 SV=1)

HSP 1 Score: 253.832 bits (647), Expect = 2.999e-75
Identity = 160/464 (34.48%), Postives = 251/464 (54.09%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLK-DDINEYN----NSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEI-----TAFKVECES-------------------------VNERPDFEI----------------PSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E + ++     Y  P+    Y NPK+ +NR L+F  L A       P+ECLDAF A+G+  LQW K+L     VT  D+ ++S+  I+ NC +N + V+ ++    K DDI E       +I V K + NV+MHL+SFDFIH+DPFG++  YLDSAF+N+RN GI+ +TSTDI+SL  +  +   R+YG  +++TEY KELA R V+A  AR+AA+CNKG +V+ +V   +++ + + + RG + A++T  K+  L+HC+ CEER +     +    +PY   L CNCH +  GKT ++LGP W+ SL +   +++++  E+  H   + Q++++ +  E      + F +   S                           +R   E+                P FYY +   ++ G   PK +K + ++   GF  SRT FDP  +RT+A L Q K I+ K
Sbjct:  231 EADTDVQVCPNYSIPQKTDSYFNPKMKLNRLLIFCTLAAL-AEERKPLECLDAFGATGIMGLQWAKHLGNAVRVTINDLNENSVTLIQENCHLNKLKVMVDSKEKEKSDDIFEEGEKNLGNIKVTKMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNIRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVE-ENPYRQ-LPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRML-FESLHHGLDDIQTLIKTLIFESECTPQSQFSIHAPSNLNKQEENGVFIKTTDDTTTDNYIAQGKRKSNEVITNLGKKQKTDVSTEHPPFYYNIHRHSIKGMNMPKLKKFLCYLSQAGFRVSRTHFDPMGVRTDAPLMQFKSILLK 690
[Close]
BLAST of TRMT1-like vs. UniProt/SwissProt
Match: sp|A2RSY6|TRM1L_MOUSE (TRMT1-like protein OS=Mus musculus OX=10090 GN=Trmt1l PE=1 SV=1)

HSP 1 Score: 252.292 bits (643), Expect = 7.752e-75
Identity = 159/462 (34.42%), Postives = 249/462 (53.90%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNS---ITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMR-LIYGEITAFKVECES---------------VNERPDFEI------------------------------PSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E + +I     Y  P+    Y NPK+ +NR+++F  L A       P+ECLDAF A+G+  LQW K+L     VT  D+ ++S+  I+ NC +N + VV ++    + D  E + +   I V + + NV+MHL+SFDFIH+DPFG++  YLDSAF+N+RN GI+ +TSTDI+SL  +  +   R+YG  +++TEY KELA R V+A  AR+AA+CNKG +V+ +V   +++ + + + RG + A++T  K+  L+HC+ CEER +     +    +PY   L CNCH +  GKT ++LGP W+ SL +   +++++  E+  H   + Q +++ LI+      + +C +               V    D  I                              P FYY +   ++ G   PK +K +  +   GF  SRT FDP  IRT+A L Q K I+ K
Sbjct:  228 ETDTDIQVFPNYSIPQKTDSYFNPKMKLNRQIIFCTLAAL-AKERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEDDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVE-ENPYRQ-LPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRML-FESIHHGLDDIQPLIKTLIFESECTPQSQCSTHAPSNTNKQEENGVFVKTTDDTTIDIYSAQGKRKSNEMAINLAKKQKTDASTAHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLK 685
[Close]
BLAST of TRMT1-like vs. UniProt/SwissProt
Match: sp|Q496Z9|TRM1L_RAT (TRMT1-like protein OS=Rattus norvegicus OX=10116 GN=Trmt1l PE=2 SV=1)

HSP 1 Score: 251.521 bits (641), Expect = 1.627e-74
Identity = 158/462 (34.20%), Postives = 249/462 (53.90%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINE---YNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMR-LIYGEITAFKVEC-----------------------------ESVNERPDFEI----------------PSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E + +I     Y  P+    Y NPK+ +NR+++F  L A       P+ECLDAF A+G+  LQW K+L     VT  D+ ++S+  I+ NC +N + VV ++    + D  E       I V + + NV+MHL+SFDFIH+DPFG++  YLDSAF+N+RN GI+ +TSTDI+SL  +  +   R+YG  +++TEY KELA R V+A  AR+AA+CNKG +V+ +V   +++ + + + RG + A++T  K+  L+HC+ CEER +     +    +PY   L CNCH +  GKT ++LGP W+ SL +   +++++  E+  H   + Q +++ LI+      + +C                              +  +R   E+                P FYY +   ++ G   PK +K +  +   GF  SRT FDP  IRT+A+L Q K I+ K
Sbjct:  224 ETDTDIQVFPNYSIPQKTDSYFNPKMKLNRQIIFCTLAAL-AEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDGLEDCSTAGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGVEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVE-ENPYKQ-LPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRML-FESIHHGLDDIQPLIKTLIFESECTPQSQCSVHAPSNTNKQEENGVFVKTTDDTTIDIYSAQGKRKSNEMAINVAKKQKTDASTAHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDASLTQFKSILLK 681
[Close]
BLAST of TRMT1-like vs. TrEMBL
Match: A0A091PK47 (tRNA (guanine(26)-N(2))-dimethyltransferase (Fragment) OS=Leptosomus discolor OX=188344 GN=N330_12181 PE=3 SV=1)

HSP 1 Score: 294.664 bits (753), Expect = 4.355e-89
Identity = 172/451 (38.14%), Postives = 248/451 (54.99%), Query Frame = 3 
Query:  147 YQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKD----DINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIY--GEITAFK-------------VEC----ESVNERPD--------------------------FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            Y +P+    Y NPK+ +NR+L+F  L A       P+ECLDAF A+G+  LQW K+L     VT  D  ++S+  IR NC +N I V  NT  +  D    D  E  +SI V K + NVIMHL+SFDFIH+DPFG++  YLDSAF+N+RN GI+ LTSTDI+SL  +  +  LR+YG  +++TEY KELA R VIA   R+AA+CNKG +V+L+V   +++ + + + RG S A+D+  K+  L+HC+ CEER +     +    +PY   L C+CH +  GKT V LGP W+G+L +   + ++   E  Q+   E QS+++ +    E T  K              EC    ++ N  PD                           E P+FYY +   ++ G   PK  K + ++   G+  SRT FDP  +RTNA L Q K ++ K
Sbjct:  164 YSTPQKTDSYFNPKMKLNRQLIFCAL-AVLAEERKPIECLDAFGATGIMGLQWAKHLKSSVKVTINDCNENSVMMIRENCHLNKIKVRLNTKEDDNDEAMGDGEENTDSIEVTKMDANVIMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSLTSTDISSLYAKAQHVALRHYGCNIVRTEYYKELAARIVIAAVTRAAARCNKGIEVLLAVALEHFVLVVVRVLRGPSPADDSAKKIRYLIHCQWCEERIFQKEGNMVE-ENPYQQ-LPCDCHGSMPGKTAVVLGPLWSGALFNAGFLRRMY-FEAVQYGLDEAQSLLKTLVCEAECTTLKHYSTHGPYDENKQEECGVYIKTPNASPDSYSVLGKRKNDEVIQNSAKRQKSENSAEHPAFYYNIHRHSIKGMNMPKLNKFLNYLSEAGYRVSRTHFDPMGVRTNAPLAQFKTVLMK 610
[Close]
BLAST of TRMT1-like vs. TrEMBL
Match: A0A3M0K586 (C2H2-type domain-containing protein OS=Hirundo rustica rustica OX=333673 GN=DUI87_14605 PE=3 SV=1)

HSP 1 Score: 295.434 bits (755), Expect = 5.614e-89
Identity = 164/431 (38.05%), Postives = 249/431 (57.77%), Query Frame = 3 
Query:  147 YQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDI----NEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAF-----------------KVECESV------NERPDF--EIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            + +P+    Y NPK+ +NR+L+F  L    G  + P+ECLDAF A+G+  LQW K+L     VT  D  ++S+  I+ NC +N + V  N      D+      E +++I V K + NV+MHL+SFDFIH+DPFGS+  YLDSAF+N+RN GI+ LTSTDI+SL  +  +  LR+YG  +++TEY KELA RTVIA   R+AA+CNKG +V+L+V   +++ + + + RG + A+D+  KV  L+HC+ CEER +     +    +PY   L C+C+ +  GKT V LGP W+G+L +   + +++  E  Q+   E QS+++ +  E                     K + E V       +RP+   E P FYY +   ++ G   PK  K ++++   G+  SRT FDP  +RTNA L Q K ++ K
Sbjct:  206 HSTPQKTDSYFNPKMKLNRQLIFCALAVLAGERK-PIECLDAFGATGIMGLQWAKHLRSSVKVTINDCNENSVTMIKENCHLNKMKVKLNIREEDNDETVGNGEESSDTIEVTKMDANVVMHLRSFDFIHLDPFGSSVSYLDSAFRNVRNFGIVSLTSTDISSLYAKAQHVALRHYGCNIVRTEYYKELAARTVIAAVTRAAARCNKGIEVLLAVALEHFVLVVVRVLRGPTPADDSAKKVRYLIHCQWCEERVFQKEGNMVE-ENPYQQ-LPCDCYGSMPGKTAVLLGPLWSGALFNTGFLRRMLV-EAVQYGLDEAQSLLKTLVCEAECTTPKHFSTHSPGDENKQGKRKSEEVLRSTAKRQRPEHSAEHPPFYYNIHRHSIKGMNMPKLNKFLSYLSEAGYRVSRTHFDPMGVRTNAPLAQFKTVLMK 632
[Close]
BLAST of TRMT1-like vs. TrEMBL
Match: A0A1D5NZG5 (tRNA methyltransferase 1 like OS=Gallus gallus OX=9031 GN=TRMT1L PE=3 SV=2)

HSP 1 Score: 296.59 bits (758), Expect = 8.295e-89
Identity = 167/451 (37.03%), Postives = 245/451 (54.32%), Query Frame = 3 
Query:  147 YQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISN----LKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIY--GEITAFK-------------VECESVNERPDF------------------------------EIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            Y +P+    Y NPK+ +NR+L+F  L A       P+ECLDAF A+G+  LQW K+L     VT  D  ++S+  I+ NC +N + V  NT          D  E +N+I V K + NVIMHL+SFDFIH+DPFG++  YLDSAF+N+RN GI+ LTSTDI+SL  +  +  LR+YG  +++TEY KELA RTVIA   R+AA+CNKG +V+L+V   +++ + + + RG S A+D+  K+  L+HC+ CEER +     +    +PY   L C+CH +  G+T V LGP W+G+L +   + +++  E  Q+   E Q +++ +    E T  K              EC    + PD                               E P+FYY +   ++ G   PK  K +  +   G+  SRT FDP  +RTNA L Q K ++ K
Sbjct:  253 YSTPQKTDSYFNPKMKLNRQLIFCAL-AVLAEERKPIECLDAFGATGIMGLQWAKHLRSSVKVTINDCNENSVTMIQENCHLNKMKVKVNTKEEDNYEAIGDGEENSNTIEVTKMDANVIMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSLTSTDISSLYAKAQHVALRHYGCNIVRTEYYKELAARTVIAAVTRAAARCNKGIEVLLAVALEHFVLVVIRVLRGPSPADDSAKKIRYLIHCQWCEERIFQKEGNMVE-ENPYQQ-LPCDCHGSMPGRTAVVLGPLWSGALFNTGFLRRML-FEAVQYGLDEVQPLLKTVICEAECTTSKNFSTHSPFDENKQEECGVYIKTPDMLAESDVVPGKRKNNEVMRNATKRQKTDNSAEHPAFYYNIHRHSIKGMNMPKLNKFLNCLSEAGYRVSRTHFDPMGVRTNAPLAQFKTVLMK 699
[Close]
BLAST of TRMT1-like vs. TrEMBL
Match: A0A3B3IIX2 (tRNA (guanine(26)-N(2))-dimethyltransferase OS=Oryzias latipes OX=8090 GN=trmt1l PE=3 SV=1)

HSP 1 Score: 290.041 bits (741), Expect = 9.038e-88
Identity = 169/464 (36.42%), Postives = 256/464 (55.17%), Query Frame = 3 
Query:   99 IMLYFENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIY--GEITAFK------------VEC--------------------------ESVNE----RPD--FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            IM     NV +L +  Y +P+ +  Y N K+  NR+LVF  L A      NP+ECLDAF A+G+  LQW K+L     VT  D+ D  ++ I+ NC++N+I V   + +   +D      ++ V+K + NVIMHL+ FD+IH+DPFG+   YLD+AF+N+RN GI+ +TSTD  SL  ++PN   R+Y   +++TEY KELA R V+A  AR+AA+CNKG +V+L+V   +++ + + + RG + A+++  K+ +L+HC+ CEER +    KL  +VD   + L CNCH +  GKT V LGP W+G L +   + ++++    QH   + Q +++ +    E T  K            VEC                          ES N     +PD   E P FYY +   ++ G   PK  K + ++   GF  SRT FDP  +RT+ATL Q K ++ K
Sbjct:  128 IMKELGTNVQLLPN--YSTPQKSDTYFNRKMKTNRQLVFCSL-AVLAEERNPLECLDAFGATGIMGLQWAKHLRNSVKVTITDISDTCVKMIKENCELNNIRVDGGSRTPRGNDAQPIA-TVEVVKMDANVIMHLRPFDYIHLDPFGTAVNYLDAAFRNVRNMGIISVTSTDTGSLYAKSPNVTQRHYSCHIVRTEYYKELAARMVLASVARAAARCNKGMEVLLAVALEHFVLVVVRVLRGPTQADESAKKLRKLVHCQWCEERVFL---KLGNMVD---DTLPCNCHGSLPGKTAVLLGPLWSGPLFNTGFLRRMLSAA-VQHSMDDIQPLVKTLICESECTTLKSLVHGSSALTNQVECGVVIKTLQEGGEAGPTDQSGKRKLGEESGNVLKKIKPDASLEHPPFYYSIHRHSIRGMNMPKLNKFLQYLTEAGFRVSRTHFDPTGVRTDATLQQFKSVLTK 580
[Close]
BLAST of TRMT1-like vs. TrEMBL
Match: G1MQJ5 (tRNA (guanine(26)-N(2))-dimethyltransferase OS=Meleagris gallopavo OX=9103 GN=TRMT1L PE=3 SV=1)

HSP 1 Score: 291.197 bits (744), Expect = 9.789e-88
Identity = 170/464 (36.64%), Postives = 251/464 (54.09%), Query Frame = 3 
Query:  114 ENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISN----LKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIY--GEITAFK-------------VECESVNERPDF--------------------------------EIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            E N ++     Y +P+    Y NPK+ +NR+L+F  L A       P+ECLDAF A+G+  LQW K+L     VT  D  ++S+  I+ NC +N + V  NT          D +E  ++I V K + NVIMHL+SFDFIH+DPFG++  YLDSAF+N+RN GI+ LTSTDI+SL  +  +  LR+YG  +++TEY KELA RTVIA  ARSAA+CNKG +V+L+V   +++ + + + RG S A+D+  K+  L+HC+ CEER +     +    +PY   L C+CH +  G+T V LGP W+G+L +   + +++  E  Q+   E Q +++ +    E T  K              EC    + PD                                 E P+FYY +   ++ G   PK  K + ++   G+  SRT FDP  +RTNA L Q K ++ K
Sbjct:  153 EANTDVQVLPNYFTPQKTDSYFNPKMKLNRQLIFCAL-AVLAEERKPIECLDAFGATGIMGLQWAKHLRSSVKVTINDCNENSVTMIQENCHLNKMKVKVNTKKEDNYEAIGDGDESTDTIEVTKMDANVIMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSLTSTDISSLYAKAQHVALRHYGCNIVRTEYYKELAARTVIAAVARSAARCNKGIEVLLAVALEHFVLVVVRVLRGPSPADDSAKKIRYLIHCQWCEERIFQKEGNMVE-ENPYQQ-LPCDCHGSMPGRTAVILGPLWSGALFNTGFLRRML-FEAVQYGLDEVQPLLKTVVCEAECTTSKNFSTHSPSDENKQEECGVYIKTPDMLAESDVMPDSGKRKNNEVMRNATKRQKTDNSAEHPAFYYNIHRHSIKGMNMPKLNKFLNYLSEAGYRVSRTHFDPMGVRTNAPLAQFKTVLMK 612
[Close]
BLAST of TRMT1-like vs. Ensembl Cavefish
Match: trmt1l (tRNA methyltransferase 1 like [Source:NCBI gene;Acc:103036451])

HSP 1 Score: 276.559 bits (706), Expect = 3.275e-85
Identity = 160/468 (34.19%), Postives = 252/468 (53.85%), Query Frame = 3 
Query:   99 IMLYFENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDI---GVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGE---------------ITAFKVEC--------------------------ESVN------ERPDFEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            IM     NV ++ +  + +P+    Y N K+  NR+LVF  L A      +P+ECLDAF A+G+  LQW K+L     VT  D+ +  ++ I+ NC +N I   G  T        D +    ++ V K + NVIMHL++FD+IH+DPFG+   YLD+AF+N+RN GI+ +TSTD  SL +++ N  LR+YG ++++TEY +ELA R V+A  AR+AA+CNKG +V+L+V   +++ + + + RG + A+++  K+ +LLHC+ CEER +     +  + +     L C CH +  GKT V+LGP W+GSL +   + +++     QH  ++ Q +++ +  E               + A +VEC                          ES N           E P+FYY +   ++ G   PK  K + ++   GF  SRT FDP  +RT+ATL Q K ++ K
Sbjct:  207 IMKELGTNVQLMPN--HSTPQKTDTYFNRKMKTNRQLVFCSL-AVLAEERSPLECLDAFGATGIMGLQWAKHLRNAVKVTINDINEACVKMIKENCHLNHIRADGGRTPRQPEGAGDSDTPIATVEVSKMDANVIMHLRAFDYIHLDPFGTAVNYLDAAFRNVRNLGIVSVTSTDTGSLYSKSLNVTLRHYGCQIVRTEYYRELAARMVVASIARAAARCNKGIEVLLAVALEHFVLVVVRVLRGPTQADESAKKLRQLLHCQWCEERVFLKPGSM--VEENLYRQLPCQCHGSMPGKTAVELGPLWSGSLFNTGFLRRMLVAA-VQHSMEDIQPLVKTLICEADCTTLKSFSVTGHSVLANQVECGVVIKTLQKVEEADTADQSGKRKTGEESSNVVKKLKSDASLEHPAFYYSIHRHSIRGMNMPKLNKFLQYLTEAGFRVSRTHFDPTGVRTDATLEQFKSVLTK 668
[Close]
BLAST of TRMT1-like vs. Ensembl Cavefish
Match: trmt1 (tRNA methyltransferase 1 [Source:NCBI gene;Acc:103032882])

HSP 1 Score: 81.2629 bits (199), Expect = 5.774e-16
Identity = 83/391 (21.23%), Postives = 167/391 (42.71%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMH-----LKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHC-------------RICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKII-----NGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMN--VGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEII 1343
            E+ +  L+  +ASGL ++++   +P    VTA D    +   I  N K N++  +                 +   + + +++M+      + +D I +DP+GS SP+LD+A + +   G+L +T TD+A +   +  T    YG+  LK++Y  ELA+R ++    + A    +  + ++SV+   YI + + ++ G +    +  K + + +C             RI + +    S    P V         NC     G+     GP W   + + + V+K++     N   F   SK  + ++ ++  E+                +IP  YY L  ++  V    P   +  + +   G+  S +    +A++T+A  G + +I+
Sbjct:  187 EDGLRVLEGLAASGLRSVRFALEVPGLKSVTANDCSAKAAALIARNAKYNNVAHL-----------------LHASQKDASMLMYEMRGKKERYDVIDLDPYGSPSPFLDAAVQAVSEGGLLCITCTDMAVMAGNSGETCYSKYGSVSLKSKYCHELALRIILHSLDQRANVYQRYIEPLISVSVDFYIRVFVRVRTGQATVKHSASKQALVYNCVGCGAFHIQRMGKRILQGKHMKFSAATGPPVG-------MNCDH--CGQRHQLGGPVWAEPIHNLEFVQKVLAAVSGNPSRFG-TSKRIEGVLSMVTEELQ---------------DIP-LYYVLDQLSSTVHCNTPAMLQFRSALLHAGYKVSFSHACKNAVKTDAPAGVLWDIM 534
[Close]
BLAST of TRMT1-like vs. Ensembl Sea Lamprey
Match: trmt1l (tRNA methyltransferase 1-like [Source:ZFIN;Acc:ZDB-GENE-041014-189])

HSP 1 Score: 248.054 bits (632), Expect = 1.025e-75
Identity = 144/450 (32.00%), Postives = 238/450 (52.89%), Query Frame = 3 
Query:  174 YLNPKLS-VNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTN----TISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGA-----ARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGE-------------------------------------ITAFKVECESV------NERPD----FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            + NP++   NR+LVF  L A       P+ CLDAF A+G+  LQW K+L     VT  D+ + S+  +  NC++N + V  +         + +    +  + V + + NV+MHL++FD+IH+DPFG+   YLD+AF+N+RN+GI+ +TSTD++SL  + PN  LR+Y   +++TEY  ELA R V+  A      R+A +CNKG +V+L+V   +++ + + + RG   A++   ++  L+HC+ CEER + P   +    +PY+ +L C+CH +  G+T ++LGP W+GSL +   + +++  E  QH  ++ Q +++ + GE                                     I + K   E         +R D     E P FYY +   ++ G   PK    +  +   GF ASRT FDP +IRT+ATL Q+  ++ +
Sbjct:  172 FFNPRMKKPNRQLVFCALAALT-QERKPLACLDAFGATGIMGLQWAKHLGNTVRVTINDVSEASVRMMEENCRLNGMTVTESWPDSDEGGEEVEGEAEDRLVEVTQYDANVLMHLRAFDYIHLDPFGTAVDYLDAAFRNVRNHGIVSITSTDLSSLYCKVPNVALRHYHCNLVRTEYYHELAARMVLTAAVSACLCRAAGRCNKGVEVLLAVALEHFVLVVVRVLRGPGHADECARRLRRLVHCQWCEERVFAPDSHMLS-ENPYS-VLPCDCHNSMPGRTAIELGPMWSGSLFNSGFLRRMLF-EAVQHEVEDVQPLLKTLAGEAECTNVRKYALTNVAAHTSQGRSLELSYEVAVNDMLYIASGKRRSEEAAGGAGKRQRGDGGFSTEHPPFYYSIHRHSIKGMNMPKLNHFLASLTEAGFRASRTHFDPTSIRTDATLPQINAVLVQ 617
[Close]
BLAST of TRMT1-like vs. Ensembl Sea Lamprey
Match: trmt1 (tRNA methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-060810-40])

HSP 1 Score: 91.6633 bits (226), Expect = 5.150e-20
Identity = 74/286 (25.87%), Postives = 137/286 (47.90%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLP-LKTIVTAVDMKDDSIERIRVNCKMNDIG-VVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDK-------------LAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIING 1058
            E  V+ L+A +ASGL ++++ K +P +K+I+T  D   +++  I  N +MN +  +VT + S+          S+ + KS      H +SFD + +DP+GS   +LD+A +++   G+L +T TD+A +   +  T    YG+  LK ++  E+A+R ++      + + ++    +L+++   YI + + I  G +    +  K + + +C  C      P  K               P V P       NC     G+     GP W G++ D + V+KII+ 
Sbjct:  140 EEGVKVLEALAASGLRSIRFAKEIPGIKSIITN-DFSKNAVAAINKNIEMNQVQHLVTASYSDA---------SMLMYKSK----NHKESFDVVDLDPYGSPVQFLDAAVQSVNEGGLLCVTCTDMAVMAGNSGETCYSKYGSMSLKAKFCHEMALRIILHCLDLHSNRYHRYIVPLLAISADFYIRVFVRIFSGQAKVKMSASKQALVYNCVGCGSFHLQPMGKSTAHNSGLKFTAATGPPVGP-------NCE--NCGQRHHLGGPIWTGAIHDINYVQKIISA 402
[Close]
BLAST of TRMT1-like vs. Ensembl Yeast
Match: TRM1 (tRNA methyltransferase; two forms of protein are made by alternative translation starts; localizes to both nucleus and mitochondrion to produce modified base N2,N2-dimethylguanosine in tRNAs in both compartments; nuclear Trm1p is evenly distributed around inner nuclear membrane in WT, but mislocalizes as puncta near ER-nucleus junctions in spindle pole body (SPB) mutants; both Trm1p inner nuclear membrane targeting and maintenance depend upon SPB [Source:SGD;Acc:S000002527])

HSP 1 Score: 94.7449 bits (234), Expect = 2.868e-21
Identity = 88/377 (23.34%), Postives = 165/377 (43.77%), Query Frame = 3 
Query:  255 VECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDIN--EYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRN-PNTVLRNY-GAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLA------------------PIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSK-EFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMNVGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNA 1316
            +  L+A SA+GL A+++   +P    V A D+  +++E I+ N + N    V N +    DD N   Y N  T  K           F  I +DP+G+ +P++D+A +++   G++++T TD++ L     P      Y GA ++  E   E A+R V+    ++AAK  K  + +LS++   Y+ + +++K       + +       HC  C      P  +++                  P VD      +   H           GP + G L + + +E+++     +HR + +     + I G ++  K E   +++ P +  P+    +  + V    P  +KV+  + S GF  S T   P +++TNA
Sbjct:  134 INILEALSATGLRAIRYAHEIPHVREVIANDLLPEAVESIKRNVEYNS---VENIVKPNLDDANVLMYRNKATNNK-----------FHVIDLDPYGTVTPFVDAAIQSIEEGGLMLVTCTDLSVLAGNGYPEKCFALYGGANMVSHESTHESALRLVLNLLKQTAAKYKKTVEPLLSLSIDFYVRVFVKVKTSPIEVKNVMSSTMTTYHCSRCGSYHNQPLGRISQREGRNNKTFTKYSVAQGPPVDTKCKFCEGTYHLA---------GPMYAGPLHNKEFIEEVLRINKEEHRDQDDTYGTRKRIEGMLSLAKNE---LSDSPFYFSPNHIASVIKLQV----PPLKKVVAGLGSLGFECSLTHAQPSSLKTNA 480
[Close]
BLAST of TRMT1-like vs. Ensembl Nematostella
Match: EDO48806 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIG7])

HSP 1 Score: 83.5741 bits (205), Expect = 3.344e-17
Identity = 66/277 (23.83%), Postives = 123/277 (44.40%), Query Frame = 3 
Query:  255 VECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHL------KSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYP---------SDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLV 1040
            V  L+  +ASGL ++++   +P    V A D+  D+   I  N K N +                 N+ ++  K++ +++M+       + F FI +DP+G+ +P+LD A + + + G+L++T TD+  L   + +     YG   LK ++  E+A+R +++     A +  +    +LS++   YI + +++   +S    T  K S + HC  C    +           S K  P + P  +     C     GK  +  GP W   + D D V
Sbjct:   94 VTILEGLAASGLRSVRYALEVPGIHHVIANDISADAFSLIENNVKHNKV-----------------NHIVSASKNDASLLMYQYRYPASRRFTFIDLDPYGTAAPFLDGAVQAVADGGVLLVTCTDMGVLCGNHNDACYGKYGGMSLKAKFCHEMALRLLLSSIESHANRYKRYILPLLSMSVDFYIRVFVQVFTSASEVKRTASKQSLVYHCTGCGSFHFQQVGRRIEEGVSKKYPPALGPPVDRSCDQC----GGKFHLG-GPIWTEPMHDTDFV 348
[Close]
BLAST of TRMT1-like vs. Ensembl Medaka
Match: trmt1l (tRNA methyltransferase 1 like [Source:NCBI gene;Acc:101165126])

HSP 1 Score: 290.041 bits (741), Expect = 3.402e-91
Identity = 169/464 (36.42%), Postives = 256/464 (55.17%), Query Frame = 3 
Query:   99 IMLYFENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIY--GEITAFK------------VEC--------------------------ESVNE----RPD--FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            IM     NV +L +  Y +P+ +  Y N K+  NR+LVF  L A      NP+ECLDAF A+G+  LQW K+L     VT  D+ D  ++ I+ NC++N+I V   + +   +D      ++ V+K + NVIMHL+ FD+IH+DPFG+   YLD+AF+N+RN GI+ +TSTD  SL  ++PN   R+Y   +++TEY KELA R V+A  AR+AA+CNKG +V+L+V   +++ + + + RG + A+++  K+ +L+HC+ CEER +    KL  +VD   + L CNCH +  GKT V LGP W+G L +   + ++++    QH   + Q +++ +    E T  K            VEC                          ES N     +PD   E P FYY +   ++ G   PK  K + ++   GF  SRT FDP  +RT+ATL Q K ++ K
Sbjct:  128 IMKELGTNVQLLPN--YSTPQKSDTYFNRKMKTNRQLVFCSL-AVLAEERNPLECLDAFGATGIMGLQWAKHLRNSVKVTITDISDTCVKMIKENCELNNIRVDGGSRTPRGNDAQPIA-TVEVVKMDANVIMHLRPFDYIHLDPFGTAVNYLDAAFRNVRNMGIISVTSTDTGSLYAKSPNVTQRHYSCHIVRTEYYKELAARMVLASVARAAARCNKGMEVLLAVALEHFVLVVVRVLRGPTQADESAKKLRKLVHCQWCEERVFL---KLGNMVD---DTLPCNCHGSLPGKTAVLLGPLWSGPLFNTGFLRRMLSAA-VQHSMDDIQPLVKTLICESECTTLKSLVHGSSALTNQVECGVVIKTLQEGGEAGPTDQSGKRKLGEESGNVLKKIKPDASLEHPPFYYSIHRHSIRGMNMPKLNKFLQYLTEAGFRVSRTHFDPTGVRTDATLQQFKSVLTK 580
[Close]
BLAST of TRMT1-like vs. Ensembl Medaka
Match: trmt1l (tRNA methyltransferase 1 like [Source:NCBI gene;Acc:101165126])

HSP 1 Score: 290.426 bits (742), Expect = 8.537e-91
Identity = 169/464 (36.42%), Postives = 256/464 (55.17%), Query Frame = 3 
Query:   99 IMLYFENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIY--GEITAFK------------VEC--------------------------ESVNE----RPD--FEIPSFYYFLKNMNV-GNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYK 1349
            IM     NV +L +  Y +P+ +  Y N K+  NR+LVF  L A      NP+ECLDAF A+G+  LQW K+L     VT  D+ D  ++ I+ NC++N+I V   + +   +D      ++ V+K + NVIMHL+ FD+IH+DPFG+   YLD+AF+N+RN GI+ +TSTD  SL  ++PN   R+Y   +++TEY KELA R V+A  AR+AA+CNKG +V+L+V   +++ + + + RG + A+++  K+ +L+HC+ CEER +    KL  +VD   + L CNCH +  GKT V LGP W+G L +   + ++++    QH   + Q +++ +    E T  K            VEC                          ES N     +PD   E P FYY +   ++ G   PK  K + ++   GF  SRT FDP  +RT+ATL Q K ++ K
Sbjct:  188 IMKELGTNVQLLPN--YSTPQKSDTYFNRKMKTNRQLVFCSL-AVLAEERNPLECLDAFGATGIMGLQWAKHLRNSVKVTITDISDTCVKMIKENCELNNIRVDGGSRTPRGNDAQPIA-TVEVVKMDANVIMHLRPFDYIHLDPFGTAVNYLDAAFRNVRNMGIISVTSTDTGSLYAKSPNVTQRHYSCHIVRTEYYKELAARMVLASVARAAARCNKGMEVLLAVALEHFVLVVVRVLRGPTQADESAKKLRKLVHCQWCEERVFL---KLGNMVD---DTLPCNCHGSLPGKTAVLLGPLWSGPLFNTGFLRRMLSAA-VQHSMDDIQPLVKTLICESECTTLKSLVHGSSALTNQVECGVVIKTLQEGGEAGPTDQSGKRKLGEESGNVLKKIKPDASLEHPPFYYSIHRHSIRGMNMPKLNKFLQYLTEAGFRVSRTHFDPTGVRTDATLQQFKSVLTK 640
[Close]
BLAST of TRMT1-like vs. Ensembl Medaka
Match: trmt1 (tRNA methyltransferase 1 [Source:NCBI gene;Acc:101168669])

HSP 1 Score: 73.9442 bits (180), Expect = 1.131e-13
Identity = 81/386 (20.98%), Postives = 161/386 (41.71%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICE----ERAWYP---------SDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKII-----NGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMN--VGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEII 1343
            E  +  L+  +ASGL ++++   +P    +TA D    +   I  N + N +G +      L+    + +  +  ++   +       +D I +DP+GS   +LD+A +++   G+L +T TD+A +   +  T    YG+  +K +Y  E+A+R ++    + AA   +  + +LSV+   YI + + +  G +   ++  K + L +C  C     +R             S    P V P      C  H    G      GP W   + D   V+K++     N   F   SK  + ++ ++  E+                ++P  YY + N++  +    P   +  + +   G   S +    +AI+T+A    + +I+
Sbjct:  176 EQGLRVLEGLAASGLRSVRFALEVPGLHSITANDFSSKAAALIARNAQYNGVGHL------LQASCRDASMLMYEMRKKKD------RYDVIDLDPYGSPVTFLDAAVQSVSEGGLLCITCTDMAVMAGNSGETCYSKYGSISIKAKYCHEMALRIILHSLDQRAAVYQRYIQPLLSVSVDFYIRVFVRVFTGQATVKNSASKQALLYNCIGCGSFHLQRMGRKTINGKNVKYSAATGPPVGPECQ--HCG-HRHQLG------GPIWAEPIHDLRFVQKVLSAVSGNPSRFG-TSKRIEGVLSMVTEELE---------------DVP-LYYTIDNLSSTLHCNTPPLLQFRSALLHAGHRVSMSHACKNAIKTDAPPAAIWDIM 523
[Close]
BLAST of TRMT1-like vs. Ensembl Medaka
Match: trmt1 (tRNA methyltransferase 1 [Source:NCBI gene;Acc:101168669])

HSP 1 Score: 73.559 bits (179), Expect = 1.814e-13
Identity = 69/310 (22.26%), Postives = 133/310 (42.90%), Query Frame = 3 
Query:  246 ENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICE----ERAWYP---------SDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKII-----NGENFQHRSKEFQSIMRLIYGEI 1121
            E  +  L+  +ASGL ++++   +P    +TA D    +   I  N + N +G +      L+    + +  +  ++   +       +D I +DP+GS   +LD+A +++   G+L +T TD+A +   +  T    YG+  +K +Y  E+A+R ++    + AA   +  + +LSV+   YI + + +  G +   ++  K + L +C  C     +R             S    P V P      C  H    G      GP W   + D   V+K++     N   F   SK  + ++ ++  E+
Sbjct:  148 EQGLRVLEGLAASGLRSVRFALEVPGLHSITANDFSSKAAALIARNAQYNGVGHL------LQASCRDASMLMYEMRKKKD------RYDVIDLDPYGSPVTFLDAAVQSVSEGGLLCITCTDMAVMAGNSGETCYSKYGSISIKAKYCHEMALRIILHSLDQRAAVYQRYIQPLLSVSVDFYIRVFVRVFTGQATVKNSASKQALLYNCIGCGSFHLQRMGRKTINGKNVKYSAATGPPVGPECQ--HCG-HRHQLG------GPIWAEPIHDLRFVQKVLSAVSGNPSRFG-TSKRIEGVLSMVTEEL 435
[Close]
BLAST of TRMT1-like vs. Planmine SMEST
Match: SMESG000005888.1 (SMESG000005888.1)

HSP 1 Score: 868.611 bits (2243), Expect = 0.000e+0
Identity = 420/421 (99.76%), Postives = 420/421 (99.76%), Query Frame = 3 
Query:  102 MLYFENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMNVGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYKMINNK 1364
            MLYFENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFC SSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMNVGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYKMINNK
Sbjct:    1 MLYFENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCSSSENPVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMNVGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYKMINNK 421
[Close]
BLAST of TRMT1-like vs. Planmine SMEST
Match: SMESG000005888.1 (SMESG000005888.1)

HSP 1 Score: 702.59 bits (1812), Expect = 0.000e+0
Identity = 339/339 (100.00%), Postives = 339/339 (100.00%), Query Frame = 3 
Query:  348 MKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMNVGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYKMINNK 1364
            MKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMNVGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYKMINNK
Sbjct:    1 MKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMNVGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYKMINNK 339
[Close]
BLAST of TRMT1-like vs. Planmine SMEST
Match: SMESG000062895.1 (SMESG000062895.1)

HSP 1 Score: 92.4337 bits (228), Expect = 6.850e-20
Identity = 100/423 (23.64%), Postives = 185/423 (43.74%), Query Frame = 3 
Query:  171 VYLNPKLSVNRELVFEVLNAFCGSSENPV------EC------LDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGA-KVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICE--------ERAWYPSDKLA---PIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMN-VGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYKMINNK 1364
            V+ NP    NR+L   ++N F  +  N +      EC       +A SA+GL ++++ K +P    + A D+   ++E I+ N + N +  +         DIN  + ++ + +++       K F  + +DP+GS S +LD+A + + N G+L +T TD A L      T +  YG+  + K     E  IR ++     ++++     K ++S +   Y  + +++    S       K+  +  C  C          R   PS        I + +  ++  NC E   G   V  GP W   + D D   ++I+  N ++    F +I R+I G ++  K E          + P +Y   K  + V +  P   ++ + I + GFL S +   P+A++TNAT   + +I+   +  K
Sbjct:   17 VFYNPVQEFNRDLTISIINYFNKTRCNNLSKVKNSECKESLKIFEALSATGLRSVRFAKEIPNVGKIVANDIDPIAVELIKENVEQNGVSALV--------DINCGDANMYMYEAH----FKQKKFHVVDLDPYGSASKFLDAAVQIVTNGGLLCVTCTDAAVLCGAALGTSMGKYGSVTIHKLGSSHEQGIRILLHAIQSASSRHGLYIKPLVSFSVDFYFRVFVQVFDSPSTVKSIASKLGMIYFCVGCHTFHVQKLLNREPMPSGGGGGGEKISNSHGPVVGTNCDE--CGGRFVIGGPIWIDPIHDRDFCSQLIDDLN-RNPDCNFGTIKRII-GMLSLAKEEL--------LDSPLYYEVDKLASIVRSITPSLLEIRSAIINAGFLVSSSHCSPNALKTNATPSILWDIMRSYLREK 415
[Close]
BLAST of TRMT1-like vs. Planmine SMEST
Match: SMESG000062895.1 (SMESG000062895.1)

HSP 1 Score: 92.4337 bits (228), Expect = 8.033e-20
Identity = 100/423 (23.64%), Postives = 185/423 (43.74%), Query Frame = 3 
Query:  171 VYLNPKLSVNRELVFEVLNAFCGSSENPV------EC------LDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDIGVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSPYLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGA-KVLKTEYVKELAIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLLKVSELLHCRICE--------ERAWYPSDKLA---PIVDPYANLLQCNCHETTAGKTGVKLGPFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESVNERPDFEIPSFYYFLKNMN-VGNRWPKFEKVITFIRSQGFLASRTQFDPDAIRTNATLGQMKEIIYKMINNK 1364
            V+ NP    NR+L   ++N F  +  N +      EC       +A SA+GL ++++ K +P    + A D+   ++E I+ N + N +  +         DIN  + ++ + +++       K F  + +DP+GS S +LD+A + + N G+L +T TD A L      T +  YG+  + K     E  IR ++     ++++     K ++S +   Y  + +++    S       K+  +  C  C          R   PS        I + +  ++  NC E   G   V  GP W   + D D   ++I+  N ++    F +I R+I G ++  K E          + P +Y   K  + V +  P   ++ + I + GFL S +   P+A++TNAT   + +I+   +  K
Sbjct:   22 VFYNPVQEFNRDLTISIINYFNKTRCNNLSKVKNSECKESLKIFEALSATGLRSVRFAKEIPNVGKIVANDIDPIAVELIKENVEQNGVSALV--------DINCGDANMYMYEAH----FKQKKFHVVDLDPYGSASKFLDAAVQIVTNGGLLCVTCTDAAVLCGAALGTSMGKYGSVTIHKLGSSHEQGIRILLHAIQSASSRHGLYIKPLVSFSVDFYFRVFVQVFDSPSTVKSIASKLGMIYFCVGCHTFHVQKLLNREPMPSGGGGGGEKISNSHGPVVGTNCDE--CGGRFVIGGPIWIDPIHDRDFCSQLIDDLN-RNPDCNFGTIKRII-GMLSLAKEEL--------LDSPLYYEVDKLASIVRSITPSLLEIRSAIINAGFLVSSSHCSPNALKTNATPSILWDIMRSYLREK 420
The following BLAST results are available for this feature:
BLAST of TRMT1-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TRMT1L5.291e-7834.91tRNA methyltransferase 1 like [Source:HGNC Symbol;... [more]
TRMT1L4.153e-3338.07tRNA methyltransferase 1 like [Source:HGNC Symbol;... [more]
TRMT12.836e-1523.03tRNA methyltransferase 1 [Source:HGNC Symbol;Acc:H... [more]
TRMT12.836e-1523.03tRNA methyltransferase 1 [Source:HGNC Symbol;Acc:H... [more]
TRMT12.836e-1523.03tRNA methyltransferase 1 [Source:HGNC Symbol;Acc:H... [more]
back to top
BLAST of TRMT1-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
trm-12.913e-1922.52tRNA (guanine(26)-N(2))-dimethyltransferase [Sour... [more]
back to top
BLAST of TRMT1-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG63889.210e-1521.70gene:FBgn0032430 transcript:FBtr0080367[more]
back to top
BLAST of TRMT1-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
trmt1l7.132e-8834.97tRNA methyltransferase 1-like [Source:ZFIN;Acc:ZDB... [more]
trmt1l1.098e-8734.97tRNA methyltransferase 1-like [Source:ZFIN;Acc:ZDB... [more]
trmt13.066e-1922.86tRNA methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
back to top
BLAST of TRMT1-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ca28.644e-8535.93carbonic anhydrase 2 [Source:Xenbase;Acc:XB-GENE-4... [more]
ca26.192e-8133.83carbonic anhydrase 2 [Source:Xenbase;Acc:XB-GENE-4... [more]
ca21.413e-8034.63carbonic anhydrase 2 [Source:Xenbase;Acc:XB-GENE-4... [more]
ca21.862e-8034.63carbonic anhydrase 2 [Source:Xenbase;Acc:XB-GENE-4... [more]
ca22.090e-8034.63carbonic anhydrase 2 [Source:Xenbase;Acc:XB-GENE-4... [more]
back to top
BLAST of TRMT1-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Trmt1l1.063e-7534.42tRNA methyltransferase 1 like [Source:MGI Symbol;A... [more]
Trmt11.096e-1622.98tRNA methyltransferase 1 [Source:MGI Symbol;Acc:MG... [more]
Trmt11.096e-1622.98tRNA methyltransferase 1 [Source:MGI Symbol;Acc:MG... [more]
Trmt11.156e-1622.98tRNA methyltransferase 1 [Source:MGI Symbol;Acc:MG... [more]
Trmt13.153e-1522.40tRNA methyltransferase 1 [Source:MGI Symbol;Acc:MG... [more]
back to top
BLAST of TRMT1-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A5D7S3|TRM1L_BOVIN1.981e-7734.63TRMT1-like protein OS=Bos taurus OX=9913 GN=TRMT1L... [more]
sp|Q7Z2T5|TRM1L_HUMAN2.541e-7734.91TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT... [more]
sp|Q5R5T0|TRM1L_PONAB2.999e-7534.48TRMT1-like protein OS=Pongo abelii OX=9601 GN=TRMT... [more]
sp|A2RSY6|TRM1L_MOUSE7.752e-7534.42TRMT1-like protein OS=Mus musculus OX=10090 GN=Trm... [more]
sp|Q496Z9|TRM1L_RAT1.627e-7434.20TRMT1-like protein OS=Rattus norvegicus OX=10116 G... [more]
back to top
BLAST of TRMT1-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A091PK474.355e-8938.14tRNA (guanine(26)-N(2))-dimethyltransferase (Fragm... [more]
A0A3M0K5865.614e-8938.05C2H2-type domain-containing protein OS=Hirundo rus... [more]
A0A1D5NZG58.295e-8937.03tRNA methyltransferase 1 like OS=Gallus gallus OX=... [more]
A0A3B3IIX29.038e-8836.42tRNA (guanine(26)-N(2))-dimethyltransferase OS=Ory... [more]
G1MQJ59.789e-8836.64tRNA (guanine(26)-N(2))-dimethyltransferase OS=Mel... [more]
back to top
BLAST of TRMT1-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
trmt1l3.275e-8534.19tRNA methyltransferase 1 like [Source:NCBI gene;Ac... [more]
trmt15.774e-1621.23tRNA methyltransferase 1 [Source:NCBI gene;Acc:103... [more]
back to top
BLAST of TRMT1-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
trmt1l1.025e-7532.00tRNA methyltransferase 1-like [Source:ZFIN;Acc:ZDB... [more]
trmt15.150e-2025.87tRNA methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
back to top
BLAST of TRMT1-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
TRM12.868e-2123.34tRNA methyltransferase; two forms of protein are m... [more]
back to top
BLAST of TRMT1-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO488063.344e-1723.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of TRMT1-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
trmt1l3.402e-9136.42tRNA methyltransferase 1 like [Source:NCBI gene;Ac... [more]
trmt1l8.537e-9136.42tRNA methyltransferase 1 like [Source:NCBI gene;Ac... [more]
trmt11.131e-1320.98tRNA methyltransferase 1 [Source:NCBI gene;Acc:101... [more]
trmt11.814e-1322.26tRNA methyltransferase 1 [Source:NCBI gene;Acc:101... [more]
back to top
BLAST of TRMT1-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000005888.10.000e+099.76SMESG000005888.1[more]
SMESG000005888.10.000e+0100.00SMESG000005888.1[more]
SMESG000062895.16.850e-2023.64SMESG000062895.1[more]
SMESG000062895.18.033e-2023.64SMESG000062895.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024492 ID=SMED30024492|Name=TRMT1-like|organism=Schmidtea mediterranea sexual|type=transcript|length=1417bp
TTTTTTTGTAAATTTCAAGATTTGAATTGCATATTTCAACAGTGAAATTT
AATTCTTTCATTTAAAATTGAAATTTTAAAAATTAATTAATAAATTGAAT
AATGTTGTATTTTGAAAATAATGTAAATATATTATCAAGTGAAGAATATC
AATCTCCAAAAAATGCTGTTGTGTATTTAAATCCTAAGTTATCAGTTAAT
AGAGAATTGGTATTTGAGGTTTTAAATGCGTTCTGCGGTTCATCTGAAAA
TCCTGTTGAATGTTTAGATGCTTTTTCCGCATCTGGTTTATGTGCGCTAC
AGTGGAAAAAAAATTTACCGTTAAAAACTATTGTTACTGCTGTGGACATG
AAAGATGATAGTATTGAAAGAATCAGAGTAAATTGCAAAATGAATGACAT
TGGTGTAGTTACTAATACAATTTCTAATCTAAAAGATGATATTAATGAAT
ATAATAATTCTATAACAGTGATAAAGTCTAATGTTAATGTCATTATGCAT
TTGAAATCATTTGATTTCATTCACATGGATCCGTTTGGTAGTACATCTCC
CTATTTAGATTCCGCATTTAAAAATCTTCGCAACAATGGTATTCTTGTTT
TAACTTCAACTGATATTGCGTCATTATTAACGAGAAATCCAAATACCGTG
TTGAGAAATTACGGCGCTAAAGTATTGAAAACTGAATATGTTAAGGAATT
GGCTATTCGTACGGTTATTGCTGGAGCAGCTCGATCTGCAGCAAAATGCA
ATAAAGGTTTCAAAGTAATTTTATCTGTCACAGATAGAAATTACATTTTT
ATAGCGTTGGAGATCAAAAGGGGGAGCAGTTTTGCTAACGATACCCTGTT
GAAAGTAAGTGAATTGTTGCATTGCCGTATTTGCGAGGAGCGGGCTTGGT
ATCCCTCGGATAAACTGGCACCTATTGTCGACCCGTATGCCAATCTATTG
CAATGCAATTGTCACGAAACCACCGCAGGGAAAACCGGTGTCAAGCTTGG
CCCATTCTGGAACGGAAGCCTCTGTGATTATGACTTGGTTGAGAAAATTA
TCAATGGGGAAAATTTCCAACATCGATCGAAAGAATTTCAATCGATAATG
CGATTGATTTACGGCGAAATCACCGCATTTAAAGTCGAATGTGAATCTGT
TAATGAGCGCCCGGATTTTGAAATTCCCAGTTTTTATTATTTTTTAAAAA
ATATGAATGTCGGAAATCGATGGCCAAAATTTGAAAAGGTTATAACTTTC
ATCCGATCTCAAGGATTTCTCGCCTCTCGGACACAATTTGACCCAGATGC
TATCAGAACAAACGCGACGCTCGGGCAGATGAAGGAGATTATTTATAAAA
TGATCAATAATAAATGAATTCGTTTTTTTTATATCGATATATTATTTATT
AAATCAATGTTTTTTCG
back to top

protein sequence of SMED30024492-orf-1

>SMED30024492-orf-1 ID=SMED30024492-orf-1|Name=SMED30024492-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=422bp
MLYFENNVNILSSEEYQSPKNAVVYLNPKLSVNRELVFEVLNAFCGSSEN
PVECLDAFSASGLCALQWKKNLPLKTIVTAVDMKDDSIERIRVNCKMNDI
GVVTNTISNLKDDINEYNNSITVIKSNVNVIMHLKSFDFIHMDPFGSTSP
YLDSAFKNLRNNGILVLTSTDIASLLTRNPNTVLRNYGAKVLKTEYVKEL
AIRTVIAGAARSAAKCNKGFKVILSVTDRNYIFIALEIKRGSSFANDTLL
KVSELLHCRICEERAWYPSDKLAPIVDPYANLLQCNCHETTAGKTGVKLG
PFWNGSLCDYDLVEKIINGENFQHRSKEFQSIMRLIYGEITAFKVECESV
NERPDFEIPSFYYFLKNMNVGNRWPKFEKVITFIRSQGFLASRTQFDPDA
IRTNATLGQMKEIIYKMINNK*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000049tRNA binding
GO:0003676nucleic acid binding
GO:0008168methyltransferase activity
GO:0016740transferase activity
GO:0003723RNA binding
GO:0004809tRNA (guanine-N2-)-methyltransferase activity
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR042296tRNA_met_Trm1_C
IPR029063SAM-dependent_MTases
IPR002905Trm1
Vocabulary: biological process
TermDefinition
GO:0008033tRNA processing
GO:0030488tRNA methylation
GO:0032259methylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 107..127
NoneNo IPR availableGENE3DG3DSA:3.40.50.150coord: 2..341
e-value: 1.4E-69
score: 236.2
NoneNo IPR availablePANTHERPTHR10631:SF1TRMT1-LIKE PROTEINcoord: 350..416
coord: 13..335
NoneNo IPR availableCDDcd02440AdoMet_MTasescoord: 55..168
e-value: 2.41993E-4
score: 38.1799
IPR042296tRNA methyltransferase, Trm1, C-terminalGENE3DG3DSA:3.30.56.70coord: 361..417
e-value: 3.3E-10
score: 41.6
IPR002905tRNA methyltransferase, Trm1PFAMPF02005TRMcoord: 17..414
e-value: 1.0E-57
score: 196.0
IPR002905tRNA methyltransferase, Trm1PANTHERPTHR10631N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASEcoord: 350..416
coord: 13..335
IPR002905tRNA methyltransferase, Trm1PROSITEPS51626SAM_MT_TRM1coord: 1..414
score: 69.835
IPR029063S-adenosyl-L-methionine-dependent methyltransferaseSUPERFAMILYSSF53335S-adenosyl-L-methionine-dependent methyltransferasescoord: 2..414