Pachytene checkpoint protein 2 homolog

Overview


Name	Pachytene checkpoint protein 2 homolog
Smed ID	SMED30024431
Length (bp)	1523

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Pachytene checkpoint protein 2 homolog (SMED30024431) t-SNE clustered cells

Violin plots show distribution of expression levels for Pachytene checkpoint protein 2 homolog (SMED30024431) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Pachytene checkpoint protein 2 homolog (SMED30024431) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Pachytene checkpoint protein 2 homolog (SMED30024431) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30024431

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30024431	SMESG000040170.1	SmedASXL_002672	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
parenchyma	SMED30024431	SMESG000040170.1	Contig54859	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
parenchyma	SMED30024431	SMESG000040170.1	Contig54859	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
testis primordium	SMED30024431	SMESG000040170.1	PL06021A2B05_SE3	GPL10652	PMID:20844018 Wang et al., 2010

Note: Hover over icons to view figure legend

Homology

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Human
Match: TRIP13 (thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307])

HSP 1 Score: 360.918 bits (925), Expect = 4.356e-120
Identity = 205/419 (48.93%), Postives = 284/419 (67.78%), Query Frame = 3

Query:   69 SRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVAL----DKQIDYLKLEARFI 1310
            S  +++EV +  SST K+E     +   L + NI F    + + D     FL +NV S+S+I  +  V +S  ++ +  ++ +H++QLNE     E   E    NIIAA +W+LP  +F  LWDSLVY   +KS LL+Y  + LLFSD ++  ++I+WN+++LLHGPPGTGKTSLC+ALAQKL+IRLS RY +G +IEINSHSLFSKWFSESGKLV KM +K+ + +++KD++ FV+IDEVESLT  R A  +G EPSDAIRVVN++LTQ+D+IK + NV +LTTSN+T+ ID AF+DR DI+ +IG P+A + + I  SCL ELM  +II P  QL++ R L+ + F +  +SK SL L  +S+K  G SGR LRKLPFLAHA +++    +I   L AL    DKQ +  K  A +I
Sbjct:   18 SPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTEFD---EPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETE-NIIAANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDKQFEERKKLAAYI 432

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Human
Match: TRIP13 (thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307])

HSP 1 Score: 205.297 bits (521), Expect = 3.186e-62
Identity = 111/227 (48.90%), Postives = 156/227 (68.72%), Query Frame = 3

Query:  108 STVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDE 785
            ST K+E     +   L + NI F    + + D     FL +NV S+S+I  +  V +S  ++ +  ++ +H++QLNE     E   E    NIIAA +W+LP  +F  LWDSLVY   +KS LL+Y  + LLFSD ++  ++I+WN+++LLHGPPGTGKTSLC+ALAQKL+IRLS RY +G +IEINSHSLFSKWFSESGKLV KM +K+ + +++KD++ FV+IDE
Sbjct:   27 STAKKEDINLSVRKLLNRHNIVFGDYTWTEFD---EPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETE-NIIAANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDE 249

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Human
Match: NVL (nuclear VCP like [Source:HGNC Symbol;Acc:HGNC:8070])

HSP 1 Score: 80.8777 bits (198), Expect = 2.063e-15
Identity = 58/200 (29.00%), Postives = 97/200 (48.50%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKS 1025
            W  +   ++I+ EL     + +   D      +++   + LL GPPG GKT L +A+A +  +      NF   I +    L + +  ES + V    +++F+  +N  + C +  DEV++L   R    S  E   ++RVVN LLT++D ++    VF++  +N  D ID A L   R D  +F+G P       ILK+
Sbjct:  383 WADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGV-LLAGPPGCGKTLLAKAVANESGL------NF---ISVKGPELLNMYVGESERAV----RQVFQRAKNS-APCVIFFDEVDALCPRR----SDRETGASVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPADRLAILKT 563

HSP 2 Score: 61.2326 bits (147), Expect = 2.853e-9
Identity = 48/164 (29.27%), Postives = 82/164 (50.00%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHY---PNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILKS 1025
            +LLHGPPG GKT L  A+A +L +          ++++ +  + S    ES     + +++LFE   + ++ C + IDE++++T  R+ A    E     R+V  LLT +D + +      V V+  +N  D++D A     R D  I +G P   S   IL++
Sbjct:  104 VLLHGPPGCGKTLLAHAIAGELDL---------PILKVAAPEIVSGVSGES----EQKLRELFEQAVS-NAPCIIFIDEIDAITPKREVASKDME----RRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRERILQT 249

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Human
Match: NVL (nuclear VCP like [Source:HGNC Symbol;Acc:HGNC:8070])

HSP 1 Score: 80.4925 bits (197), Expect = 2.295e-15
Identity = 58/200 (29.00%), Postives = 97/200 (48.50%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKS 1025
            W  +   ++I+ EL     + +   D      +++   + LL GPPG GKT L +A+A +  +      NF   I +    L + +  ES + V    +++F+  +N  + C +  DEV++L   R    S  E   ++RVVN LLT++D ++    VF++  +N  D ID A L   R D  +F+G P       ILK+
Sbjct:  391 WADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGV-LLAGPPGCGKTLLAKAVANESGL------NF---ISVKGPELLNMYVGESERAV----RQVFQRAKNS-APCVIFFDEVDALCPRR----SDRETGASVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPADRLAILKT 571

[Close]

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKS 1025
            W  +   ++I+ EL     + +   D      +++   + LL GPPG GKT L +A+A +  +      NF   I +    L + +  ES + V    +++F+  +N  + C +  DEV++L   R    S  E   ++RVVN LLT++D ++    VF++  +N  D ID A L   R D  +F+G P       ILK+
Sbjct:  391 WADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGV-LLAGPPGCGKTLLAKAVANESGL------NF---ISVKGPELLNMYVGESERAV----RQVFQRAKNS-APCVIFFDEVDALCPRR----SDRETGASVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPADRLAILKT 571

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Celegans
Match: pch-2 (Putative pachytene checkpoint protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q09535])

HSP 1 Score: 221.861 bits (564), Expect = 6.625e-67
Identity = 124/285 (43.51%), Postives = 188/285 (65.96%), Query Frame = 3

Query:  378 NIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDY--MEFADTXXXXXXXXXX--XXXXXXXGFSGRTLRKLPFLAHAK 1220
            +II ++ W LPC +FD +W++L+Y  N+K+E+++Y  +    S+  +   +I+ N++ILL GPPGTGKTSLC+ LAQ LSIR++ +Y+   M+EINSHSLFSKWFSESGKLV KM  ++ E  E++  + FV+IDEVESL   R+++ S +EPSDAIR VN+LLTQ+D+I+   NV +L TSNL   +D A +DR DI   +G P+  + Y +LKS ++EL    ++     + ++   DY   +  DTK  ++        ++++  G SGR +  LP L ++K
Sbjct:  118 SIIGSQLWQLPCVEFDSIWENLIYDSNLKNEVMSYVAALARLSEKHVNTKIINVNRLILLTGPPGTGKTSLCKGLAQHLSIRMNDKYSKSVMLEINSHSLFSKWFSESGKLVQKMFDQIDELAEDEKCMVFVLIDEVESLGMCRESSSSRSEPSDAIRAVNALLTQIDRIRRRDNVLILCTSNLESTLDKALVDRADIVKNVGQPSDFARYSMLKSSIMELARIGVV-----IDNEVHTDYWPQDICDTKAPRNEFTEILFKIAQEARGLSGRAISMLPTLVYSK 397

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Celegans
Match: rpt-4 (Probable 26S proteasome regulatory subunit 10B [Source:UniProtKB/Swiss-Prot;Acc:O17071])

HSP 1 Score: 78.9518 bits (193), Expect = 1.583e-15
Identity = 59/177 (33.33%), Postives = 88/177 (49.72%), Query Frame = 3

Query:  498 LFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILK 1022
            LF    I P      K  LL GPPGTGKT L RA+A +L        NF   +++ S ++  K+  ES    A+M++++F Y  +    C V +DE++++ G R+ +   +   +  R +  LL QLD       V V+  +N  D +D A L   R D +I IG P  +S   ILK
Sbjct:  175 LFKRVGITPP-----KGCLLFGPPGTGKTLLARAVASQLDC------NF---LKVVSSAIVDKYIGES----ARMIREMFNYARDHQP-CIVFMDEIDAIGG-RRFSEGTSADREIQRTLMELLNQLDGFDSLGKVKVIMATNRPDTLDPALLRPGRLDRKIEIGLPNEQSRLEILK 331

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Celegans
Match: rpt-4 (Probable 26S proteasome regulatory subunit 10B [Source:UniProtKB/Swiss-Prot;Acc:O17071])

HSP 1 Score: 78.5666 bits (192), Expect = 1.665e-15
Identity = 59/177 (33.33%), Postives = 88/177 (49.72%), Query Frame = 3

Query:  498 LFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILK 1022
            LF    I P      K  LL GPPGTGKT L RA+A +L        NF   +++ S ++  K+  ES    A+M++++F Y  +    C V +DE++++ G R+ +   +   +  R +  LL QLD       V V+  +N  D +D A L   R D +I IG P  +S   ILK
Sbjct:  167 LFKRVGITPP-----KGCLLFGPPGTGKTLLARAVASQLDC------NF---LKVVSSAIVDKYIGES----ARMIREMFNYARDHQP-CIVFMDEIDAIGG-RRFSEGTSADREIQRTLMELLNQLDGFDSLGKVKVIMATNRPDTLDPALLRPGRLDRKIEIGLPNEQSRLEILK 323

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Celegans
Match: cdc-48.2 (Transitional endoplasmic reticulum ATPase homolog 2 [Source:UniProtKB/Swiss-Prot;Acc:P54812])

HSP 1 Score: 75.8702 bits (185), Expect = 2.917e-14
Identity = 60/206 (29.13%), Postives = 92/206 (44.66%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            W  +    N+K EL       +   +      + PS     + +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES   V  +  K         + C +  DE++S+   R  ++ G+    A RV+N +LT++D +    NVF++  +N  D ID A L   R D  I+I  P   S   I K+ L
Sbjct:  481 WSDIGGLQNVKRELQELVQYPVEHPEKYLKFGMQPS-----RGVLFYGPPGCGKTLLAKAIANEC------QANF---ISIKGPELLTMWFGESEANVRDVFDKA-----RAAAPCVLFFDELDSIAKARGGSV-GDAGGAADRVINQVLTEMDGMNAKKNVFIIGATNRPDIIDPAVLRPGRLDQLIYIPLPDEASRLQIFKASL 666

HSP 2 Score: 64.6994 bits (156), Expect = 1.047e-10
Identity = 61/203 (30.05%), Postives = 88/203 (43.35%), Query Frame = 3

Query:  420 FDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            +DDL         IK  +        LF    + P      + ILL GPPGTGKT + RA+A +                IN   + SK   ES       ++K F   E K+S   + IDE++++   R+ A    E     R+V+ LLT +D +K   +V V+  +N  ++ID A     R D  I IG P A     IL+
Sbjct:  208 YDDLGGVRKQLAQIKEMVELPLRHPQLFKAIGVKPP-----RGILLFGPPGTGKTLIARAVANETG---------AFFFLINGPEIMSKMSGES----ESNLRKAFAECE-KNSPAILFIDEIDAIAPKREKAHGEVEK----RIVSQLLTLMDGLKTRAHVVVIAATNRPNSIDGALRRFGRFDREIDIGIPDAVGRLEILR 387

[Close]

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            W  +    N+K EL       +   +      + PS     + +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES   V  +  K         + C +  DE++S+   R  ++ G+    A RV+N +LT++D +    NVF++  +N  D ID A L   R D  I+I  P   S   I K+ L
Sbjct:  481 WSDIGGLQNVKRELQELVQYPVEHPEKYLKFGMQPS-----RGVLFYGPPGCGKTLLAKAIANEC------QANF---ISIKGPELLTMWFGESEANVRDVFDKA-----RAAAPCVLFFDELDSIAKARGGSV-GDAGGAADRVINQVLTEMDGMNAKKNVFIIGATNRPDIIDPAVLRPGRLDQLIYIPLPDEASRLQIFKASL 666

HSP 2 Score: 64.6994 bits (156), Expect = 1.047e-10
Identity = 61/203 (30.05%), Postives = 88/203 (43.35%), Query Frame = 3

Query:  420 FDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            +DDL         IK  +        LF    + P      + ILL GPPGTGKT + RA+A +                IN   + SK   ES       ++K F   E K+S   + IDE++++   R+ A    E     R+V+ LLT +D +K   +V V+  +N  ++ID A     R D  I IG P A     IL+
Sbjct:  208 YDDLGGVRKQLAQIKEMVELPLRHPQLFKAIGVKPP-----RGILLFGPPGTGKTLIARAVANETG---------AFFFLINGPEIMSKMSGES----ESNLRKAFAECE-KNSPAILFIDEIDAIAPKREKAHGEVEK----RIVSQLLTLMDGLKTRAHVVVIAATNRPNSIDGALRRFGRFDREIDIGIPDAVGRLEILR 387

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Fly
Match: pch2 (gene:FBgn0051453 transcript:FBtr0339330)

HSP 1 Score: 278.1 bits (710), Expect = 2.416e-88
Identity = 146/301 (48.50%), Postives = 198/301 (65.78%), Query Frame = 3

Query:  378 NIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQI 1280
            +I+AA + +LP  QF  LW++L+Y   +K +LL +A SAL+FS+  +  +VI+ N++ILLHGPPGTGKTSLC+ALAQKLSIR    Y + H++EINSHSLFSKWFSESGKLVA++  K+ E V + +++  V+IDEVESL   R +A+S NEP DA+RVVN++LTQLD +K  PNV +L TSNL  +ID AF+DR DIR+FIG P   +   I K  L ELM+  ++Q           + +E  D +    +           G SGRTLRKLP LAHA++        +  L  LD++I
Sbjct:  112 SIVAASHALLPAAQFVGLWENLIYETGLKEKLLKFALSALMFSEHRVDTNVIACNRLILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNKIAELVSDPNNLVCVLIDEVESLAYAR-SAMSSNEPRDAMRVVNAVLTQLDSLKTCPNVLILATSNLAQSIDLAFVDRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQR----------EVLESEDAEEGLLTQLAERSV----GLSGRTLRKLPLLAHAQY-------TSSTLFELDQKI 390

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Fly
Match: pch2 (gene:FBgn0051453 transcript:FBtr0081898)

HSP 1 Score: 278.1 bits (710), Expect = 2.416e-88
Identity = 146/301 (48.50%), Postives = 198/301 (65.78%), Query Frame = 3

Query:  378 NIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQI 1280
            +I+AA + +LP  QF  LW++L+Y   +K +LL +A SAL+FS+  +  +VI+ N++ILLHGPPGTGKTSLC+ALAQKLSIR    Y + H++EINSHSLFSKWFSESGKLVA++  K+ E V + +++  V+IDEVESL   R +A+S NEP DA+RVVN++LTQLD +K  PNV +L TSNL  +ID AF+DR DIR+FIG P   +   I K  L ELM+  ++Q           + +E  D +    +           G SGRTLRKLP LAHA++        +  L  LD++I
Sbjct:  112 SIVAASHALLPAAQFVGLWENLIYETGLKEKLLKFALSALMFSEHRVDTNVIACNRLILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNKIAELVSDPNNLVCVLIDEVESLAYAR-SAMSSNEPRDAMRVVNAVLTQLDSLKTCPNVLILATSNLAQSIDLAFVDRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQR----------EVLESEDAEEGLLTQLAERSV----GLSGRTLRKLPLLAHAQY-------TSSTLFELDQKI 390

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Fly
Match: CG10793 (gene:FBgn0029656 transcript:FBtr0070536)

HSP 1 Score: 78.5666 bits (192), Expect = 3.717e-15
Identity = 55/162 (33.95%), Postives = 84/162 (51.85%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPN-VFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCL 1031
            +LLHGPPG+GKT L +AL  +   +++          I +  + SKW  ES     K+++ LF ++  K +   +  DE+ESLT  R  A    +   + R  N LL  LD ++H  N VFVL ++NL   ID AFL R + ++ +  P A    C++   L
Sbjct:  242 LLLHGPPGSGKTLLAKALYSETQGQVT-------FFNITASIMVSKWRGES----EKILRVLF-HMAAKRAPSVIFFDEIESLTSKRDRA---TDHESSKRFKNELLQLLDGMEHSLNGVFVLASTNLPWDIDEAFLRRFEKKLLVQLPNAAERSCLINRLL 388

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Fly
Match: smid (gene:FBgn0016983 transcript:FBtr0076851)

HSP 1 Score: 78.5666 bits (192), Expect = 5.257e-15
Identity = 62/209 (29.67%), Postives = 92/209 (44.02%), Query Frame = 3

Query:  423 DDLWDSLVYCDNIKSEL-----LNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSC 1028
            D  WD +   + I+ EL         Y  +L       PS +      LL GPPG GKT L +A+A +  I      NF   I +    L + +  ES + V    +  F+   N  + C +  DE +SL   R     GN  +   R+VN LLT++D ++    V++L  +N  D ID A L   R D  +++G P       ILK+ 
Sbjct:  658 DTTWDDIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGV------LLCGPPGCGKTLLAKAIANEAGI------NF---ISVKGPELMNMYVGESERAV----RACFQRARNS-APCVIFFDEFDSLCPKRSDGGDGN--NSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILKAT 844

HSP 2 Score: 59.6918 bits (143), Expect = 4.333e-9
Identity = 53/190 (27.89%), Postives = 88/190 (46.32%), Query Frame = 3

Query:  468 ELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYP---NVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            E+L +  S   +    + PS     + +LLHGPPG GKT L RA++ +L + L         +EI +  L      ES + + ++  +   Y     S C + IDE++++ G RQ A    E     R+V+ L++ LD +K      +V V+  +   D +D     + R D  I I  P+ +    IL+
Sbjct:  265 EMLIHIKSPEFYFQLGLLPS-----RGLLLHGPPGCGKTFLARAISGQLKMPL---------MEIPATELIGGISGESEERIREVFDQAIGY-----SPCVLFIDEIDAIGGNRQWASKDME----RRIVSQLISSLDNLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKERREILR 431

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Fly
Match: smid (gene:FBgn0016983 transcript:FBtr0331850)

HSP 1 Score: 78.5666 bits (192), Expect = 5.259e-15
Identity = 62/209 (29.67%), Postives = 92/209 (44.02%), Query Frame = 3

Query:  423 DDLWDSLVYCDNIKSEL-----LNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSC 1028
            D  WD +   + I+ EL         Y  +L       PS +      LL GPPG GKT L +A+A +  I      NF   I +    L + +  ES + V    +  F+   N  + C +  DE +SL   R     GN  +   R+VN LLT++D ++    V++L  +N  D ID A L   R D  +++G P       ILK+ 
Sbjct:  641 DTTWDDIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGV------LLCGPPGCGKTLLAKAIANEAGI------NF---ISVKGPELMNMYVGESERAV----RACFQRARNS-APCVIFFDEFDSLCPKRSDGGDGN--NSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFPEQSERTEILKAT 827

HSP 2 Score: 59.6918 bits (143), Expect = 4.421e-9
Identity = 53/190 (27.89%), Postives = 88/190 (46.32%), Query Frame = 3

Query:  468 ELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYP---NVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            E+L +  S   +    + PS     + +LLHGPPG GKT L RA++ +L + L         +EI +  L      ES + + ++  +   Y     S C + IDE++++ G RQ A    E     R+V+ L++ LD +K      +V V+  +   D +D     + R D  I I  P+ +    IL+
Sbjct:  248 EMLIHIKSPEFYFQLGLLPS-----RGLLLHGPPGCGKTFLARAISGQLKMPL---------MEIPATELIGGISGESEERIREVFDQAIGY-----SPCVLFIDEIDAIGGNRQWASKDME----RRIVSQLISSLDNLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKERREILR 414

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Zebrafish
Match: trip13 (thyroid hormone receptor interactor 13 [Source:NCBI gene;Acc:393554])

HSP 1 Score: 343.969 bits (881), Expect = 8.407e-114
Identity = 188/414 (45.41%), Postives = 276/414 (66.67%), Query Frame = 3

Query:   75 ELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQIDYLKLEARFIEN 1316
            +++IEV  +  ST KR     H+   L + +      K+   DF ++ FL KNV S+++    D      V+    +L IH++ LN+         E +  +  AA  W+LP  +F  +W+SL+Y + IK++LL+Y  + + FSD ++  ++I+WN+++LLHGPPGTGKTSLC+ LAQKLSIRLS RY     +EINSHSLFSKWFSESGKLV KM +K+ E +++KD++ FV+IDEVESLT  R AA +G EPSDAIRVVNS+LTQLD+IK +PNV +LTTSN+T+ ID AF+DR DI+ +IG P+A++ + I  S L ELM ++II P  QL+S   L+ M F ++ +++ SL L ++S++ +G SGR LRK+PFLAHA + + +  ++   L A++  +D  + E   + N
Sbjct:   17 DVHIEVHVKSQSTAKRSDVRTHVLSLLDRHSTVLRSFKW--TDF-DDEFLAKNVESVTIA---DVTGPKLVDLKVHNLCIHIFTLNDDSPSTLNLEEEEELS--AANLWLLPAVEFHGVWESLIYEEGIKTQLLDYVSTTIFFSDKNVDSNLIAWNRVVLLHGPPGTGKTSLCKGLAQKLSIRLSDRYAHSQFVEINSHSLFSKWFSESGKLVTKMFQKIQELIDDKDALVFVLIDEVESLTAARSAAQAGTEPSDAIRVVNSVLTQLDQIKRHPNVVILTTSNVTEKIDLAFVDRADIKQYIGPPSAKAIFNIYLSSLEELMKRQIIYPRQQLVSLEELETMNFMESDVTRLSLCLMNISQRSVGLSGRALRKIPFLAHALYGKTSTMTLKGFLTAMEHAVDKQRQEQASLVN 422

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Zebrafish
Match: trip13 (thyroid hormone receptor interactor 13 [Source:NCBI gene;Acc:393554])

HSP 1 Score: 152.91 bits (385), Expect = 6.187e-43
Identity = 87/208 (41.83%), Postives = 128/208 (61.54%), Query Frame = 3

Query:   75 ELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSE 698
            +++IEV  +  ST KR     H+   L + +      K+   DF ++ FL KNV S+++    D      V+    +L IH++ LN+         E +  +  AA  W+LP  +F  +W+SL+Y + IK++LL+Y  + + FSD ++  ++I+WN+++LLHGPPGTGKTSLC+ LAQKLSIRLS RY     +EINSHSLFSKWFSE
Sbjct:   17 DVHIEVHVKSQSTAKRSDVRTHVLSLLDRHSTVLRSFKW--TDF-DDEFLAKNVESVTIA---DVTGPKLVDLKVHNLCIHIFTLNDDSPSTLNLEEEEELS--AANLWLLPAVEFHGVWESLIYEEGIKTQLLDYVSTTIFFSDKNVDSNLIAWNRVVLLHGPPGTGKTSLCKGLAQKLSIRLSDRYAHSQFVEINSHSLFSKWFSE 216

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Zebrafish
Match: vcp (valosin containing protein [Source:NCBI gene;Acc:327197])

HSP 1 Score: 80.4925 bits (197), Expect = 1.698e-15
Identity = 62/206 (30.10%), Postives = 96/206 (46.60%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            W+ +   D++K EL       +   D      + PS     K +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES   V ++  K  +      + C +  DE++S+   R   +     + A RV+N +LT++D +    NVF++  +N  D ID A L   R D  I+I  P  +S   ILK+ L
Sbjct:  476 WEDIGGLDDVKRELQELVQYPVEHPDKFLKFGMTPS-----KGVLFYGPPGCGKTLLAKAIANEC------QANF---ISIKGPELLTMWFGESEANVREIFDKARQA-----APCVLFFDELDSIAKARGGNVGDGGGA-ADRVINQILTEMDGMSSKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRIAILKANL 661

HSP 2 Score: 67.3958 bits (163), Expect = 2.059e-11
Identity = 51/160 (31.87%), Postives = 77/160 (48.12%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            ILL+GPPGTGKT + RA+A +                IN   + SK   ES       ++K FE  E K++   + IDE++++   R+      E     R+V+ LLT +D +K   +V V+  +N  ++ID A     R D  + IG P A     IL+
Sbjct:  241 ILLYGPPGTGKTLIARAVANETG---------AFFFLINGPEIMSKLAGES----ESNLRKAFEEAE-KNAPAIIFIDELDAIAPKREKTHGEVE----RRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQ 382

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Zebrafish
Match: vcp (valosin containing protein [Source:NCBI gene;Acc:327197])

HSP 1 Score: 80.4925 bits (197), Expect = 1.886e-15
Identity = 62/206 (30.10%), Postives = 96/206 (46.60%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            W+ +   D++K EL       +   D      + PS     K +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES   V ++  K  +      + C +  DE++S+   R   +     + A RV+N +LT++D +    NVF++  +N  D ID A L   R D  I+I  P  +S   ILK+ L
Sbjct:  476 WEDIGGLDDVKRELQELVQYPVEHPDKFLKFGMTPS-----KGVLFYGPPGCGKTLLAKAIANEC------QANF---ISIKGPELLTMWFGESEANVREIFDKARQA-----APCVLFFDELDSIAKARGGNVGDGGGA-ADRVINQILTEMDGMSSKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRIAILKANL 661

HSP 2 Score: 67.3958 bits (163), Expect = 2.189e-11
Identity = 51/160 (31.87%), Postives = 77/160 (48.12%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            ILL+GPPGTGKT + RA+A +                IN   + SK   ES       ++K FE  E K++   + IDE++++   R+      E     R+V+ LLT +D +K   +V V+  +N  ++ID A     R D  + IG P A     IL+
Sbjct:  241 ILLYGPPGTGKTLIARAVANETG---------AFFFLINGPEIMSKLAGES----ESNLRKAFEEAE-KNAPAIIFIDELDAIAPKREKTHGEVE----RRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQ 382

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Zebrafish
Match: nvl (nuclear VCP like [Source:ZFIN;Acc:ZDB-GENE-040426-2871])

HSP 1 Score: 77.0258 bits (188), Expect = 2.335e-14
Identity = 51/161 (31.68%), Postives = 85/161 (52.80%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKS 1025
            +LL GPPG GKT L +A+A +  +      NF   I +    L + +  ES + V    +++F+   N  + C +  DE+++L   R    S +E   ++RVVN LLT++D +++   VF++  +N  D ID A L   R D  +++G P A   + IL +
Sbjct:  557 LLLAGPPGCGKTLLAKAVANESGL------NF---ISVKGPELLNMYVGESERAV----RQVFQRGRNS-APCVIFFDEIDALCPRR----SEHESGASVRVVNQLLTEMDGMENRRQVFIMAATNRPDIIDPAVLRPGRLDKTLYVGLPPAADRHVILNT 699

HSP 2 Score: 60.8474 bits (146), Expect = 2.507e-9
Identity = 54/178 (30.34%), Postives = 87/178 (48.88%), Query Frame = 3

Query:  552 LLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIK---HYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPAD 1070
            LLHGPPG GKT L +A+A + ++ L         ++I++  L S    ES     + +++LFE   +  + C + IDE++++T  R+ A    E     R+V  LLT +D +        V V+  +N  D++D A     R D  I +G P   +   ILK+     + +KI  P D
Sbjct:  264 LLHGPPGCGKTLLAQAVAGETALPL---------LKISAPELVSGVSGES----EQKLRELFEQAISS-APCILFIDEIDAITPKRETASKDME----RRIVAQLLTCMDDLNSMLEPAQVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEGARMKILKT-----LCRKIRLPDD 418

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Xenopus
Match: myo6 (myosin VI [Source:Xenbase;Acc:XB-GENE-1012303])

HSP 1 Score: 351.673 bits (901), Expect = 1.309e-116
Identity = 192/404 (47.52%), Postives = 279/404 (69.06%), Query Frame = 3

Query:   75 ELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            +++++V ++ +S    +  ++H+   L +  + F    + + D   +SFL KN+ SIS+   +  + +   ++ +K  + IH++QLNE     E   E +  +++AA +W+LP   F  LWDSL+Y   IKS LL+Y  +A+LFSD ++  ++ISWN+++LLHGPPGTGKTSLC+ALAQKL+IRLS+RY +G ++EINSHSLFSKWFSESGKLV KM +K+ E + +K+++ FV+IDEVESLT  R+A+ +G EPSDAIRVVN++LTQ+D IK YPNV +L+TSNLT+ ID AF DR DI+ +IG P+  + + I  SC+ ELM  +II P  QL++ R L+ + F +  ISK SL L  +S+K  G SGR LRKLPFLAHA +++    +I   L AL   +D
Sbjct:   20 QVHVDVHQKSNSPATSQDIQSHVMQLLNRHCVVFGDYSWTEFD---DSFLMKNIHSISIADTELKLKDRQPIDLSKCKVLIHIFQLNEDGPCVESLEEENE-DLVAANHWLLPAADFHGLWDSLIYDSEIKSRLLDYIETAMLFSDKNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSYRYRYGQLVEINSHSLFSKWFSESGKLVTKMFQKIHELINDKEALVFVLIDEVESLTAARKASRAGTEPSDAIRVVNAVLTQIDHIKRYPNVVILSTSNLTEKIDVAFTDRADIKQYIGPPSPAAIFKIYLSCIEELMKCQIIYPKQQLLTLRDLEIIGFLENNISKLSLQLNEISRKSEGLSGRVLRKLPFLAHALYLQSPTVTIERFLWALSLAVD 419

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Xenopus
Match: myo6 (myosin VI [Source:Xenbase;Acc:XB-GENE-1012303])

HSP 1 Score: 349.362 bits (895), Expect = 7.693e-116
Identity = 193/405 (47.65%), Postives = 275/405 (67.90%), Query Frame = 3

Query:   72 RELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            R + I +I   +     +  ++H+   L +  + F    + + D   +SFL KN+ SIS+   +  + +   ++ +K  + IH++QLNE     E   E +  +++AA +W+LP   F  LWDSL+Y   IKS LL+Y  +A+LFSD ++  ++ISWN+++LLHGPPGTGKTSLC+ALAQKL+IRLS+RY +G ++EINSHSLFSKWFSESGKLV KM +K+ E + +K+++ FV+IDEVESLT  R+A+ +G EPSDAIRVVN++LTQ+D IK YPNV +L+TSNLT+ ID AF DR DI+ +IG P+  + + I  SC+ ELM  +II P  QL++ R L+ + F +  ISK SL L  +S+K  G SGR LRKLPFLAHA +++    +I   L AL   +D
Sbjct:    2 RSIPIHLIFHNTFPATSQDIQSHVMQLLNRHCVVFGDYSWTEFD---DSFLMKNIHSISIADTELKLKDRQPIDLSKCKVLIHIFQLNEDGPCVESLEEENE-DLVAANHWLLPAADFHGLWDSLIYDSEIKSRLLDYIETAMLFSDKNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSYRYRYGQLVEINSHSLFSKWFSESGKLVTKMFQKIHELINDKEALVFVLIDEVESLTAARKASRAGTEPSDAIRVVNAVLTQIDHIKRYPNVVILSTSNLTEKIDVAFTDRADIKQYIGPPSPAAIFKIYLSCIEELMKCQIIYPKQQLLTLRDLEIIGFLENNISKLSLQLNEISRKSEGLSGRVLRKLPFLAHALYLQSPTVTIERFLWALSLAVD 402

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Xenopus
Match: myo6 (myosin VI [Source:Xenbase;Acc:XB-GENE-1012303])

HSP 1 Score: 347.436 bits (890), Expect = 1.515e-114
Identity = 190/385 (49.35%), Postives = 268/385 (69.61%), Query Frame = 3

Query:  132 ENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            ++H+   L +  + F    + + D   +SFL KN+ SIS+   +  + +   ++ +K  + IH++QLNE     E   E +  +++AA +W+LP   F  LWDSL+Y   IKS LL+Y  +A+LFSD ++  ++ISWN+++LLHGPPGTGKTSLC+ALAQKL+IRLS+RY +G ++EINSHSLFSKWFSESGKLV KM +K+ E + +K+++ FV+IDEVESLT  R+A+ +G EPSDAIRVVN++LTQ+D IK YPNV +L+TSNLT+ ID AF DR DI+ +IG P+  + + I  SC+ ELM  +II P  QL++ R L+ + F +  ISK SL L  +S+K  G SGR LRKLPFLAHA +++    +I   L AL   +D
Sbjct:   60 QSHVMQLLNRHCVVFGDYSWTEFD---DSFLMKNIHSISIADTELKLKDRQPIDLSKCKVLIHIFQLNEDGPCVESLEEENE-DLVAANHWLLPAADFHGLWDSLIYDSEIKSRLLDYIETAMLFSDKNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSYRYRYGQLVEINSHSLFSKWFSESGKLVTKMFQKIHELINDKEALVFVLIDEVESLTAARKASRAGTEPSDAIRVVNAVLTQIDHIKRYPNVVILSTSNLTEKIDVAFTDRADIKQYIGPPSPAAIFKIYLSCIEELMKCQIIYPKQQLLTLRDLEIIGFLENNISKLSLQLNEISRKSEGLSGRVLRKLPFLAHALYLQSPTVTIERFLWALSLAVD 440

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Xenopus
Match: myo6 (myosin VI [Source:Xenbase;Acc:XB-GENE-1012303])

HSP 1 Score: 341.658 bits (875), Expect = 4.578e-113
Identity = 185/367 (50.41%), Postives = 261/367 (71.12%), Query Frame = 3

Query:  132 ENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIR 1229
            ++H+   L +  + F    + + D   +SFL KN+ SIS+   +  + +   ++ +K  + IH++QLNE     E   E +  +++AA +W+LP   F  LWDSL+Y   IKS LL+Y  +A+LFSD ++  ++ISWN+++LLHGPPGTGKTSLC+ALAQKL+IRLS+RY +G ++EINSHSLFSKWFSESGKLV KM +K+ E + +K+++ FV+IDEVESLT  R+A+ +G EPSDAIRVVN++LTQ+D IK YPNV +L+TSNLT+ ID AF DR DI+ +IG P+  + + I  SC+ ELM  +II P  QL++ R L+ + F +  ISK SL L  +S+K  G SGR LRKLPFLAHA +++
Sbjct:   23 QSHVMQLLNRHCVVFGDYSWTEFD---DSFLMKNIHSISIADTELKLKDRQPIDLSKCKVLIHIFQLNEDGPCVESLEEENE-DLVAANHWLLPAADFHGLWDSLIYDSEIKSRLLDYIETAMLFSDKNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSYRYRYGQLVEINSHSLFSKWFSESGKLVTKMFQKIHELINDKEALVFVLIDEVESLTAARKASRAGTEPSDAIRVVNAVLTQIDHIKRYPNVVILSTSNLTEKIDVAFTDRADIKQYIGPPSPAAIFKIYLSCIEELMKCQIIYPKQQLLTLRDLEIIGFLENNISKLSLQLNEISRKSEGLSGRVLRKLPFLAHALYLQ 385

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Xenopus
Match: myo6 (myosin VI [Source:Xenbase;Acc:XB-GENE-1012303])

HSP 1 Score: 340.887 bits (873), Expect = 5.874e-113
Identity = 185/367 (50.41%), Postives = 261/367 (71.12%), Query Frame = 3

Query:  132 ENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIR 1229
            ++H+   L +  + F    + + D   +SFL KN+ SIS+   +  + +   ++ +K  + IH++QLNE     E   E +  +++AA +W+LP   F  LWDSL+Y   IKS LL+Y  +A+LFSD ++  ++ISWN+++LLHGPPGTGKTSLC+ALAQKL+IRLS+RY +G ++EINSHSLFSKWFSESGKLV KM +K+ E + +K+++ FV+IDEVESLT  R+A+ +G EPSDAIRVVN++LTQ+D IK YPNV +L+TSNLT+ ID AF DR DI+ +IG P+  + + I  SC+ ELM  +II P  QL++ R L+ + F +  ISK SL L  +S+K  G SGR LRKLPFLAHA +++
Sbjct:   15 QSHVMQLLNRHCVVFGDYSWTEFD---DSFLMKNIHSISIADTELKLKDRQPIDLSKCKVLIHIFQLNEDGPCVESLEEENE-DLVAANHWLLPAADFHGLWDSLIYDSEIKSRLLDYIETAMLFSDKNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSYRYRYGQLVEINSHSLFSKWFSESGKLVTKMFQKIHELINDKEALVFVLIDEVESLTAARKASRAGTEPSDAIRVVNAVLTQIDHIKRYPNVVILSTSNLTEKIDVAFTDRADIKQYIGPPSPAAIFKIYLSCIEELMKCQIIYPKQQLLTLRDLEIIGFLENNISKLSLQLNEISRKSEGLSGRVLRKLPFLAHALYLQ 377

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Mouse
Match: Trip13 (thyroid hormone receptor interactor 13 [Source:MGI Symbol;Acc:MGI:1916966])

HSP 1 Score: 359.762 bits (922), Expect = 7.266e-120
Identity = 195/406 (48.03%), Postives = 282/406 (69.46%), Query Frame = 3

Query:   69 SRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCD-DGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            S  +++EV++   ST K+E  ++ ++  L + NI F    ++  +F ++ FL +NV S+S++  +    +   ++ +  ++ +H++QLNE     E   E    NIIAA +W+LP  +F  LWDSLVY   +KS LL+Y  + +LFSD ++  ++I+WN+++LLHGPPGTGKTSLC+ALAQKL+IRLS RY +G +IEINSHSLFSKWFSESGKLV KM +K+ + +++K+++ FV+IDEVESLT  R A  +G EPSDAIRVVN++LTQ+D+IK + NV +LTTSN+T+ ID AF+DR DI+ +IG P+A + + I  SCL ELM  +II P  QL++ R L+ + F +  +SK SL L  +S+K  G SGR LRKLPFLAHA +I+    +I   L AL   +D
Sbjct:   18 SPAVHVEVLQRSGSTAKKEDIKSSVYRLLNRHNIVFG--DYVWTEF-DDPFLSRNVQSVSIVDTELKAKDPQPIDLSACTIALHIFQLNEEGPSSENLDEETE-NIIAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTVLFSDKNVDSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKEALVFVLIDEVESLTAARNACRAGAEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPSVTIEGFLQALSLAVD 419

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Mouse
Match: Nvl (nuclear VCP-like [Source:MGI Symbol;Acc:MGI:1914709])

HSP 1 Score: 80.8777 bits (198), Expect = 1.419e-15
Identity = 55/161 (34.16%), Postives = 83/161 (51.55%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKS 1025
            ILL GPPG GKT L +A+A +  +      NF   I +    L + +  ES + V    +++F+  +N  + C +  DEV++L   R    S  E   ++RVVN LLT++D ++    VF+L  +N  D ID A L   R D  +F+G P       ILK+
Sbjct:  617 ILLAGPPGCGKTLLAKAVANESGL------NF---ISVKGPELLNMYVGESERAV----RQVFQRAKNS-APCVIFFDEVDALCPRR----SDRETGASVRVVNQLLTEMDGLETRQQVFILAATNRPDIIDPAILRPGRLDKTLFVGLPPPADRVAILKT 759

HSP 2 Score: 58.5362 bits (140), Expect = 1.568e-8
Identity = 46/164 (28.05%), Postives = 82/164 (50.00%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHY---PNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILKS 1025
            +LLHGPPG GKT L  A+A +L +          ++++ +  + S    ES     + +++LF+   + ++ C V IDE++++T  R+ A    E     R+V  LLT +D + +      V V+  +N  D++D A     R D  + +G P   +   IL++
Sbjct:  300 VLLHGPPGCGKTLLAHAIAGELDL---------PILKVAAPEIVSGVSGES----EQKLRELFDQAVS-NAPCIVFIDEIDAITPKREVASKDME----RRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREVCLGIPDEAARERILQT 445

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Mouse
Match: Vcp (valosin containing protein [Source:MGI Symbol;Acc:MGI:99919])

HSP 1 Score: 78.5666 bits (192), Expect = 8.496e-15
Identity = 61/206 (29.61%), Postives = 96/206 (46.60%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            W+ +   +++K EL       +   D      + PS     K +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES   V ++  K  +      + C +  DE++S+   R   +     + A RV+N +LT++D +    NVF++  +N  D ID A L   R D  I+I  P  +S   ILK+ L
Sbjct:  476 WEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPS-----KGVLFYGPPGCGKTLLAKAIANEC------QANF---ISIKGPELLTMWFGESEANVREIFDKARQA-----APCVLFFDELDSIAKARGGNIGDGGGA-ADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANL 661

HSP 2 Score: 67.3958 bits (163), Expect = 2.510e-11
Identity = 51/160 (31.87%), Postives = 77/160 (48.12%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            ILL+GPPGTGKT + RA+A +                IN   + SK   ES       ++K FE  E K++   + IDE++++   R+      E     R+V+ LLT +D +K   +V V+  +N  ++ID A     R D  + IG P A     IL+
Sbjct:  241 ILLYGPPGTGKTLIARAVANETG---------AFFFLINGPEIMSKLAGES----ESNLRKAFEEAE-KNAPAIIFIDELDAIAPKREKTHGEVE----RRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQ 382

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Mouse
Match: Vps4b (vacuolar protein sorting 4B [Source:MGI Symbol;Acc:MGI:1100499])

HSP 1 Score: 77.411 bits (189), Expect = 9.698e-15
Identity = 59/160 (36.88%), Postives = 80/160 (50.00%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYV-ENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIK-HYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILK 1022
            ILL GPPGTGK+ L +A+A +         N      I+S  L SKW  ES KLV    K LF+   ENK SI F  IDE++SL G R    S NE   A R+    L Q+  +      + VL  +N+   +D+A   R + RI+I  P A +   + +
Sbjct:  170 ILLFGPPGTGKSYLAKAVATEA--------NNSTFFSISSSDLVSKWLGESEKLV----KNLFQLARENKPSIIF--IDEIDSLCGSR----SENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARAAMFR 311

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Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYV-ENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIK-HYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILK 1022
            ILL GPPGTGK+ L +A+A +         N      I+S  L SKW  ES KLV    K LF+   ENK SI F  IDE++SL G R    S NE   A R+    L Q+  +      + VL  +N+   +D+A   R + RI+I  P A +   + +
Sbjct:  170 ILLFGPPGTGKSYLAKAVATEA--------NNSTFFSISSSDLVSKWLGESEKLV----KNLFQLARENKPSIIF--IDEIDSLCGSR----SENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARAAMFR 311

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BLAST of Pachytene checkpoint protein 2 homolog vs. UniProt/SwissProt
Match: sp|E1C6Q1|PCH2_CHICK (Pachytene checkpoint protein 2 homolog OS=Gallus gallus OX=9031 GN=TRIP13 PE=3 SV=1)

HSP 1 Score: 368.622 bits (945), Expect = 1.717e-122
Identity = 202/411 (49.15%), Postives = 285/411 (69.34%), Query Frame = 3

Query:   75 ELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVAL----DKQIDYLK 1292
            ++++EV ++ +ST K+E     +   L + NI F   K+ + D   + FL  NV S+S++  +  + E   ++ +KSSL IH++ LNE     E   E +  +I+AA +W+LP  +F  LW+SL+Y   +KS LL+Y  + LLFSD ++  ++ISWN+++LLHGPPGTGKTSLC+ALAQKL+IRLS+RY +G +IEINSHSLFSKWFSESGKLV KM +K+ E +++KD++ FV+IDEVESLT  R A  +G EPSDAIRVVN++L Q+D+IK YPNV +LTTSN+T+ ID AF+DR DI+ +IG P+A + + I  SCL ELM  +II P   L+S R L+ + F +  +S+ SL L  +S++  G SGR LRKLPFLAHA +I+    ++T  L AL    DKQ +  K
Sbjct:   20 QIHVEVHQKSNSTAKKEDIRMSVLKLLNRHNIVFGDYKWTEFD---DGFLNSNVQSVSIVDTELKLKERQPIDLSKSSLTIHIFHLNEEGPSIENLEEENE-DIVAANHWVLPAAEFHGLWESLIYDTEVKSHLLDYVTTTLLFSDRNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSYRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQELIDDKDALVFVLIDEVESLTAARSAFKAGTEPSDAIRVVNAVLMQIDQIKRYPNVVILTTSNITEKIDMAFVDRADIKQYIGPPSAAAIFRIYLSCLEELMKCQIIYPRQHLLSLRELEMIGFVENNVSRLSLVLKEISRRSEGLSGRVLRKLPFLAHALYIQSPSVTMTAFLQALSLVVDKQFEERK 426

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BLAST of Pachytene checkpoint protein 2 homolog vs. UniProt/SwissProt
Match: sp|Q15645|PCH2_HUMAN (Pachytene checkpoint protein 2 homolog OS=Homo sapiens OX=9606 GN=TRIP13 PE=1 SV=2)

HSP 1 Score: 360.918 bits (925), Expect = 2.092e-119
Identity = 205/419 (48.93%), Postives = 284/419 (67.78%), Query Frame = 3

Query:   69 SRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVAL----DKQIDYLKLEARFI 1310
            S  +++EV +  SST K+E     +   L + NI F    + + D     FL +NV S+S+I  +  V +S  ++ +  ++ +H++QLNE     E   E    NIIAA +W+LP  +F  LWDSLVY   +KS LL+Y  + LLFSD ++  ++I+WN+++LLHGPPGTGKTSLC+ALAQKL+IRLS RY +G +IEINSHSLFSKWFSESGKLV KM +K+ + +++KD++ FV+IDEVESLT  R A  +G EPSDAIRVVN++LTQ+D+IK + NV +LTTSN+T+ ID AF+DR DI+ +IG P+A + + I  SCL ELM  +II P  QL++ R L+ + F +  +SK SL L  +S+K  G SGR LRKLPFLAHA +++    +I   L AL    DKQ +  K  A +I
Sbjct:   18 SPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTEFD---EPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETE-NIIAANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDKQFEERKKLAAYI 432

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BLAST of Pachytene checkpoint protein 2 homolog vs. UniProt/SwissProt
Match: sp|Q5XHZ9|PCH2_RAT (Pachytene checkpoint protein 2 homolog OS=Rattus norvegicus OX=10116 GN=Trip13 PE=2 SV=1)

HSP 1 Score: 360.533 bits (924), Expect = 2.597e-119
Identity = 196/406 (48.28%), Postives = 281/406 (69.21%), Query Frame = 3

Query:   69 SRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCD-DGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            S  +++EV++   ST K+E  +  ++  L++ NI F    ++  +F +  FL +NV S+S++  +    +   ++ +  ++ +H++QLNE     E   E    NIIAA +W+LP  +F  LWDSLVY   +KS LL+Y  + LLFSD ++  ++I+WN+++LLHGPPGTGKTSLC+ALAQKL+IRLS RY +G +IEINSHSLFSKWFSESGKLV KM +K+ + +++K+++ FV+IDEVESLT  R A  +G EPSDAIRVVN++LTQ+D+IK + NV +LTTSN+T+ ID AF+DR DI+ +IG P+A + + I  SCL ELM  +II P  QL++ R L+ + F +  +SK SL L  +S+K  G SGR LRKLPFLAHA +I+    +I   L AL   +D
Sbjct:   18 SPAVHVEVLQRSGSTAKKEDIKQSVYRLLKRHNIVFG--DYVWTEF-DEPFLTRNVQSVSIVDTELKAKDPQPIDLSACTIALHIFQLNEEGPSSENLDEETE-NIIAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVDSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKEALVFVLIDEVESLTAARNACRAGAEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPSVTIEGFLQALSLAVD 419

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BLAST of Pachytene checkpoint protein 2 homolog vs. UniProt/SwissProt
Match: sp|Q3UA06|PCH2_MOUSE (Pachytene checkpoint protein 2 homolog OS=Mus musculus OX=10090 GN=Trip13 PE=1 SV=1)

HSP 1 Score: 359.762 bits (922), Expect = 5.082e-119
Identity = 195/406 (48.03%), Postives = 282/406 (69.46%), Query Frame = 3

Query:   69 SRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCD-DGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            S  +++EV++   ST K+E  ++ ++  L + NI F    ++  +F ++ FL +NV S+S++  +    +   ++ +  ++ +H++QLNE     E   E    NIIAA +W+LP  +F  LWDSLVY   +KS LL+Y  + +LFSD ++  ++I+WN+++LLHGPPGTGKTSLC+ALAQKL+IRLS RY +G +IEINSHSLFSKWFSESGKLV KM +K+ + +++K+++ FV+IDEVESLT  R A  +G EPSDAIRVVN++LTQ+D+IK + NV +LTTSN+T+ ID AF+DR DI+ +IG P+A + + I  SCL ELM  +II P  QL++ R L+ + F +  +SK SL L  +S+K  G SGR LRKLPFLAHA +I+    +I   L AL   +D
Sbjct:   18 SPAVHVEVLQRSGSTAKKEDIKSSVYRLLNRHNIVFG--DYVWTEF-DDPFLSRNVQSVSIVDTELKAKDPQPIDLSACTIALHIFQLNEEGPSSENLDEETE-NIIAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTVLFSDKNVDSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKEALVFVLIDEVESLTAARNACRAGAEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPSVTIEGFLQALSLAVD 419

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BLAST of Pachytene checkpoint protein 2 homolog vs. UniProt/SwissProt
Match: sp|D3K5L7|PCH2_PIG (Pachytene checkpoint protein 2 homolog OS=Sus scrofa OX=9823 GN=TRIP13 PE=2 SV=1)

HSP 1 Score: 355.525 bits (911), Expect = 2.061e-117
Identity = 195/403 (48.39%), Postives = 276/403 (68.49%), Query Frame = 3

Query:   78 LNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            +++EV +   ST K+E  + ++   L + NI F    + + D     FL +NV S+S++  +  V +   ++ +  ++ +H++QLNE     E   E    NIIAA +W+LP  +F  LWDSLVY   +KS LL+Y  + LLFSD ++  ++I+WN+++LLHGPPGTGKTSLC+ALAQKL+IRLS RY +G +IEINSHSLFSKWFSESGKLV +M + + + +++KD++ FV+IDEVESLT  R A  +G EPSDAIRVVN++LTQ+D+IK + NV +LTTSN+T+ ID AF+DR DIR ++G P+A + + I  SCL ELM  +II P  QL++ R L+ + F +  +SK SL L  +S+K  G SGR LRKLPFLAHA +I+    +I   L AL   +D
Sbjct:   21 VHVEVHQRSGSTAKKEDVKLNVRKLLNRHNIVFGDYTWTEFD---EPFLTRNVQSVSIVDTELKVKDPQPIDLSTCTVALHVFQLNEGGPSSENLEEETE-NIIAANHWLLPAAEFHGLWDSLVYDAEVKSHLLDYVMTTLLFSDKNVDSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTRMFQMIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITERIDVAFVDRADIRQYVGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPTVTIEGFLQALSLAVD 419

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BLAST of Pachytene checkpoint protein 2 homolog vs. TrEMBL
Match: V5SKQ2 (Pachytene checkpoint 2-like protein OS=Nodipecten subnodosus OX=330909 GN=PCH2 PE=2 SV=1)

HSP 1 Score: 380.563 bits (976), Expect = 1.412e-124
Identity = 203/422 (48.10%), Postives = 290/422 (68.72%), Query Frame = 3

Query:   21 KMSDNDSNMEMISDNFSRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCD-DGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            ++ D  S+   IS  +    +IE+ +  SST +  I + H+   L +  +++    F+  +F ++ FL ++V SI++   D  G    +++     L +H++QL E     EE  E    ++ AA +W+LP R    +WDSLV+ +N+KS+LLNYA + LLFSD  +  ++I+WNK++LLHGPPGTGKTSLC+ALAQKL +RLS RY++G +IEINSHSLFSKWFSESGKLV KM +K+ E +++K++I FV+IDEVESLT  R++A+SG+EPSDAIRVVN+LLTQLD+IK  PNV +LTTSN+T AID AF+DR DI+ +IG P+  + + I  SC+ ELM   II PA QL+  R L+ M F +   +K+SL L  ++ K  G SGRTLRKLPF+AHA F++    ++ + LVAL + +D
Sbjct:   11 ELGDGHSDSTAISPVY----HIEICQSPSSTAQGNIVKEHVLNLLHRQKVAYG--DFVLTEF-DDPFLHEHVNSIALCDSDLSGSNRQTIDLCGRELQLHVFQLQEDGPGIEELDEE---DLAAASHWLLPARDLHGMWDSLVFDENVKSQLLNYATTTLLFSDRQVDSNIITWNKVVLLHGPPGTGKTSLCKALAQKLVVRLSDRYSYGQLIEINSHSLFSKWFSESGKLVMKMFQKIQELIDDKEAIVFVLIDEVESLTSARKSAMSGSEPSDAIRVVNALLTQLDQIKRQPNVMILTTSNVTGAIDLAFVDRADIKQYIGPPSPAAIFKIFHSCINELMRVDIISPAQQLLDLRGLEAMRFMENDATKNSLVLRDIANKSHGLSGRTLRKLPFIAHAMFVQGASVTLEDFLVALSRGVD 422

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BLAST of Pachytene checkpoint protein 2 homolog vs. TrEMBL
Match: A0A210PWC5 (Pachytene checkpoint protein 2-like OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT13360 PE=3 SV=1)

HSP 1 Score: 380.178 bits (975), Expect = 1.626e-124
Identity = 200/402 (49.75%), Postives = 282/402 (70.15%), Query Frame = 3

Query:   81 NIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCD-DGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            +IE+ +  SST K  I + H+   L +  +++    F+  +F ++ FL ++V S+++   D  G    +++     L +H++QL E     EE  E    ++ AA +W+LP R    +WDSLV+ +++K +LLNYA + LLFSD  +  +VI+WNK+ILLHGPPGTGKTSLC+ALAQKL +RLS RY++G +IEINSHSLFSKWFSESGKLV KM +K+ E ++++++I FV+IDEVESLT  R++A+SG+EPSDAIRVVN+LLTQLD+IK +PNV +LTTSN+T AID AF+DR DI+ +IG P+  + + I  SC+ ELM   II PA QL+  R L+ M F +   +KSSL L  ++ K  G SGRTLRKLPF+AHA FI+    ++ E LVAL + ++
Sbjct:   27 HIEICQSPSSTAKGNIIKEHVLGLLHRQKVAYG--DFVLTEF-DDPFLHEHVKSVALCDSDLSGSNRQTIDLCGRQLRLHVFQLQEDGPGMEELDEE---DLAAATHWLLPARDLHGMWDSLVFDEDVKGQLLNYATTTLLFSDKQVDSNVITWNKVILLHGPPGTGKTSLCKALAQKLVVRLSDRYSYGQLIEINSHSLFSKWFSESGKLVMKMFQKIQELIDDQEAIVFVLIDEVESLTSARKSAMSGSEPSDAIRVVNALLTQLDQIKRHPNVMILTTSNVTGAIDLAFVDRADIKQYIGPPSPAAIFKIFHSCISELMRVDIISPAQQLLDLRGLEAMRFMENDATKSSLMLRDIANKAHGLSGRTLRKLPFIAHAMFIQSASVTLEEFLVALGQGVE 422

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BLAST of Pachytene checkpoint protein 2 homolog vs. TrEMBL
Match: A0A1S3H9M9 (pachytene checkpoint protein 2 homolog OS=Lingula unguis OX=7574 GN=LOC106152690 PE=3 SV=1)

HSP 1 Score: 376.711 bits (966), Expect = 3.611e-123
Identity = 206/424 (48.58%), Postives = 295/424 (69.58%), Query Frame = 3

Query:   30 DNDSNME-MISDNFSREL--NIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCD---DGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            D  S++E  + D+ + +L  +++V +  SS V   I ++H+   LQ+  +++  + F + D   + FL+++V +++V  CD      E   ++   +   IH+YQLNE     EE  E    ++ AA +W+LP R FD LWDSLV+  +IK++LL YA + LLFSD  +  ++ISWN+++LLHGPPGTGKTSLC+ALAQKL+IRLS RY++G +IEINSHSLFSKWFSESGKLV KM +K+ E +++ +++  V+IDEVESLT  R+A++SGNEPSDAIRVVN+LLTQ+D+IK  PNV +LTTSN+T AID AF+DR DI+ +IG P+  + Y I +SCL ELM   II P  QLI  RAL+ M F++   +K SL L  ++ K  G SGRTLRK+PFL+HA ++++   ++ E L AL + +D
Sbjct:    2 DQVSDLEDALPDSHTMQLAVHVDVCQNSSSAVSGVIIKDHVKKLLQRQRVAYHDLVFTEFD---DPFLQEHVHTVAV--CDIHSMQKEREPIDLYSAFFLIHVYQLNEDGPASEELDEE---DLAAASHWLLPTRDFDGLWDSLVFDSDIKNQLLQYASTTLLFSDRKVDSNIISWNRVVLLHGPPGTGKTSLCKALAQKLAIRLSDRYSYGQLIEINSHSLFSKWFSESGKLVMKMFQKIQELIDDPEALVCVLIDEVESLTAARKASMSGNEPSDAIRVVNALLTQIDQIKRNPNVIILTTSNVTGAIDLAFVDRADIKQYIGPPSPAAIYNIYQSCLNELMRSGIISPPQQLIDMRALEVMRFSENNATKLSLRLRQIAIKSEGLSGRTLRKIPFLSHAMYLQRPATTLEEYLGALSRAVD 417

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BLAST of Pachytene checkpoint protein 2 homolog vs. TrEMBL
Match: A0A1S3KC13 (pachytene checkpoint protein 2 homolog OS=Lingula unguis OX=7574 GN=LOC106180667 PE=3 SV=1)

HSP 1 Score: 375.555 bits (963), Expect = 8.503e-123
Identity = 201/405 (49.63%), Postives = 285/405 (70.37%), Query Frame = 3

Query:   78 LNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCD---DGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            ++++V +  SS V   I ++H+   LQ+  +++  + F + D   + FL+++V +++V  CD      E   ++   +   IH+YQLNE     EE  E    ++ AA +W+LP R FD LWDSLV+  +IK++LL YA + LLFSD  +  ++ISWN+++LLHGPPGTGKTSLC+ALAQKL+IRLS RY++G +IEINSHSLFSKWFSESGKLV KM +K+ E +++ +++  V+IDEVESLT  R+A++SGNEPSDAIRVVN+LLTQ+D+IK  PNV +LTTSN+T AID AF+DR DI+ +IG P+  + Y I +SCL ELM   II P  QLI  RAL+ M F++   +K SL L  ++ K  G SGRTLRK+PFL+HA ++++   ++ E L AL + +D
Sbjct:   21 VHVDVCQNSSSAVSGVIIKDHVKKLLQRQRVAYHDLVFTEFD---DPFLQEHVHTVAV--CDIHSMQKEREPIDLCSAFFLIHVYQLNEDGPASEELDEE---DLAAASHWLLPTRDFDGLWDSLVFDSDIKNQLLQYASTTLLFSDRKVDSNIISWNRVVLLHGPPGTGKTSLCKALAQKLAIRLSDRYSYGQLIEINSHSLFSKWFSESGKLVMKMFQKIQELIDDPEALVCVLIDEVESLTAARKASMSGNEPSDAIRVVNALLTQIDQIKRNPNVIILTTSNVTGAIDLAFVDRADIKQYIGPPSPAAIYNIYQSCLNELMRSGIISPPQQLIDMRALEVMRFSENNATKLSLRLRQIAIKSEGLSGRTLRKIPFLSHAMYLQRPATTLEEYLGALSRAVD 417

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BLAST of Pachytene checkpoint protein 2 homolog vs. TrEMBL
Match: A0A1V4JVF1 (Pachytene checkpoint 2-like protein OS=Patagioenas fasciata monilis OX=372326 GN=TRIP13 PE=3 SV=1)

HSP 1 Score: 372.474 bits (955), Expect = 1.713e-121
Identity = 201/406 (49.51%), Postives = 286/406 (70.44%), Query Frame = 3

Query:   69 SRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGV-ESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            S ++++EV+++ SST K+E     +   L + NI F   K+ + D   +SFL  NV S+S++  +  + +   ++ +KSSL +H++ LNE     E   E +  +IIAA +W+LP  +F  LW+SL+Y   +KS LL+Y  + LLFSD ++  ++ISWN+++LLHGPPGTGKTSLC+ALAQKL+IRLSHRY +G +IEINSHSLFSKWFSESGKLV KM +K+ E +++KD++ FV+IDEVESLT  R A  +G EPSDAIRVVN++LTQ+D+IK +PNV +LTTSN+T+ ID AF+DR DI+ +IG P+  + + I  SCL ELM  +II P  QL++ R L+ + F +  +S+ SL L  +S++  G SGR LRKLPFLAHA +I+    ++T  L AL   +D
Sbjct:   18 SVKIHVEVLQKSSSTAKKEDIRMSVLKLLNRHNIVFGDYKWTEFD---DSFLNSNVQSVSIVDTELNLKDRQPIDLSKSSLSLHIFHLNEEGPSSENLEEENE-DIIAANHWVLPAAEFHGLWESLIYDIEVKSHLLDYVATTLLFSDKNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSHRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQELIDDKDALVFVLIDEVESLTAARSAFKAGTEPSDAIRVVNAVLTQIDQIKRHPNVVILTTSNITEKIDMAFVDRADIKQYIGPPSTAAIFRIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSRLSLILKEISRRSEGLSGRVLRKLPFLAHALYIQSPSVTMTTFLQALSLAVD 419

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Cavefish
Match: trip13 (thyroid hormone receptor interactor 13 [Source:NCBI gene;Acc:393554])

HSP 1 Score: 316.235 bits (809), Expect = 2.368e-103
Identity = 173/396 (43.69%), Postives = 257/396 (64.90%), Query Frame = 3

Query:   93 IKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQI 1280
            + E S TV R     HI   L + ++     K+ + D   + FL+KNV SI+V+  D    S  ++   ++L IH++ L++         E +   + AA +W+LP  +   +W+SL+Y ++IK++LLNY  +A+ FSD ++  ++I+WN+++LL+GPPGTGKTSLC+ALAQKLSIR+  RY +G  +EINSHSLFSKWFSE    V ++                     VESLT  R A+ +G EPSDA+RVVNS+LTQLD++K YPNV +LTTSN+T+ ID+AFLDR DIR++IG P A + Y I  SCL ELM K++I P  QL+S   LD M +  +K+++ SL L ++++K  G SGRTLRK+PFLAH+ + + +V ++   LV++++ +
Sbjct:   13 LSEDSFTVVRAEVRTHILPLLDRHSLVTGSYKWTEFD---DEFLRKNVESIAVVDMDVLSVSEKIDLRTTNLCIHIFSLSDDGPSTLNLEEDE--ELSAANHWLLPAAELHGIWESLIYEEDIKTQLLNYVSTAIFFSDKNVDSNLITWNRVVLLYGPPGTGKTSLCKALAQKLSIRMCGRYAYGQFVEINSHSLFSKWFSEKNIHVLQVF--------------------VESLTAARNASQAGTEPSDAVRVVNSVLTQLDQLKRYPNVVILTTSNVTEKIDSAFLDRADIRMYIGPPGANAIYKIYLSCLEELMKKQVIYPRQQLLSLEELDTMGYIKSKVTELSLKLHNIAQKSAGLSGRTLRKIPFLAHSLYAKTSVVTVETFLVSMEEAV 383

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Cavefish
Match: nvl (nuclear VCP like [Source:NCBI gene;Acc:103033742])

HSP 1 Score: 83.1889 bits (204), Expect = 2.290e-16
Identity = 61/201 (30.35%), Postives = 98/201 (48.76%), Query Frame = 3

Query:  423 DDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCIL 1019
            D  WD +    +I+ EL   A  A + S        +S    +LL GPPG GKT L +A+A +  +      NF   I +    L + +  ES + V    +++F+   N  + C +  DE+++L   R    SG+E   ++RVVN LLT++D ++    VF++  +N  D ID A L   R D  +++G P     + IL
Sbjct:  636 DVTWDDIGALQDIREEL-TMAILAPVRSPEQFKALGLSAPAGVLLAGPPGCGKTLLAKAVANESGL------NF---ISVKGPELLNMYVGESERAV----RQVFQRGRNS-APCVIFFDEIDALCPRR----SGHESGASVRVVNQLLTEMDGLETRRQVFIMAATNRPDIIDPAVLRPGRLDKTLYVGLPPPADRHAIL 817

HSP 2 Score: 59.3066 bits (142), Expect = 7.590e-9
Identity = 50/178 (28.09%), Postives = 88/178 (49.44%), Query Frame = 3

Query:  552 LLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHY---PNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPAD 1070
            LLHGPPG GKT L +A+A ++ +          M+++++  L S    ES     + +++LF+   + ++ C + IDE++++T  R+ A    E     R+V  LLT +D +        V V+  +N  D++D A     R D  I +G P   +   IL++     + +K+  P D
Sbjct:  313 LLHGPPGCGKTLLAQAVAGEMEL---------PMLKVSAPELVSGVSGES----EQKLRELFDQAVS-NAPCILFIDEIDAITPKREVASKDME----RRIVAQLLTCMDDLNSLSVPAQVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEGTRLRILQT-----LCRKLRLPVD 467

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Query:  423 DDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCIL 1019
            D  WD +    +I+ EL   A  A + S        +S    +LL GPPG GKT L +A+A +  +      NF   I +    L + +  ES + V    +++F+   N  + C +  DE+++L   R    SG+E   ++RVVN LLT++D ++    VF++  +N  D ID A L   R D  +++G P     + IL
Sbjct:  636 DVTWDDIGALQDIREEL-TMAILAPVRSPEQFKALGLSAPAGVLLAGPPGCGKTLLAKAVANESGL------NF---ISVKGPELLNMYVGESERAV----RQVFQRGRNS-APCVIFFDEIDALCPRR----SGHESGASVRVVNQLLTEMDGLETRRQVFIMAATNRPDIIDPAVLRPGRLDKTLYVGLPPPADRHAIL 817

HSP 2 Score: 59.3066 bits (142), Expect = 7.590e-9
Identity = 50/178 (28.09%), Postives = 88/178 (49.44%), Query Frame = 3

Query:  552 LLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHY---PNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPAD 1070
            LLHGPPG GKT L +A+A ++ +          M+++++  L S    ES     + +++LF+   + ++ C + IDE++++T  R+ A    E     R+V  LLT +D +        V V+  +N  D++D A     R D  I +G P   +   IL++     + +K+  P D
Sbjct:  313 LLHGPPGCGKTLLAQAVAGEMEL---------PMLKVSAPELVSGVSGES----EQKLRELFDQAVS-NAPCILFIDEIDAITPKREVASKDME----RRIVAQLLTCMDDLNSLSVPAQVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEGTRLRILQT-----LCRKLRLPVD 467

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Cavefish
Match: zgc:136908 (zgc:136908 [Source:ZFIN;Acc:ZDB-GENE-060312-22])

HSP 1 Score: 75.8702 bits (185), Expect = 4.409e-14
Identity = 59/206 (28.64%), Postives = 93/206 (45.15%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            W+ +   D +K EL       + + D      + PS     + +L +GPPG GKT L +A+A +       + NF   + I    L + WF ES   V  +  K       + + C +  DE++S+   R           A RV+N +LT++D + +  NVF++  +N  D ID A L   R D  I+I  P   S   IL++ L
Sbjct:  419 WEDIGGLDEVKRELQELVQYPVEYPDKFLKFGMTPS-----RGVLFYGPPGCGKTLLAKAIANEC------QANF---VSIKGPELLTMWFGESEANVRDVFDKA-----RQAAPCILFFDELDSIAKSRGGGAGDAG-GAADRVINQILTEMDGMTNKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDMPSRTAILRANL 604

HSP 2 Score: 67.3958 bits (163), Expect = 1.982e-11
Identity = 61/216 (28.24%), Postives = 99/216 (45.83%), Query Frame = 3

Query:  435 DSLVYCDN--IKSELL----NYAY------------SALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            D++++C+   IK E++     Y++             A LFS   + P      + ILL+GPPGTGKT + RA+A +                IN   + SK   ES       ++K FE  E K++   + IDE++++   R+      E     R+V+ LLT +D +K   +V V+  +N  +++D A     R D  I IG P +     IL+
Sbjct:  134 DTIIHCEGEPIKREVVYGFGRYSFVMLFYTLCVTLQHARLFSSKRVPP------RGILLYGPPGTGKTLVARAVANETG---------AFFFLINGPEIMSKLAGES----ESNLRKAFEEAE-KNAPAIIFIDELDAIAPKREKTHGEVE----RRIVSQLLTLMDGLKQRVHVVVMAATNRPNSVDPALRRFGRFDREIDIGIPDSTGRLEILQ 325

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Cavefish
Match: katnal2 (katanin catalytic subunit A1 like 2 [Source:NCBI gene;Acc:103028825])

HSP 1 Score: 75.0998 bits (183), Expect = 4.685e-14
Identity = 54/158 (34.18%), Postives = 82/158 (51.90%), Query Frame = 3

Query:  525 SVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPN-VFVLTTSNLTDAIDTAFLDRTDIRIFIGNPT 995
             ++S  K +LL+GPPGTGKT L +A+A + +              I++ S+ SKW  +S KLV    + LFE +    +   + +DE+ES+   R     G E   + R+   LL Q+D +    + VFVL  SNL   +D A L R + RI +G P+
Sbjct:  238 GILSPWKGLLLYGPPGTGKTMLAKAVATECNTTF---------FNISASSIVSKWRGDSEKLV----RVLFE-LARYHAPSTIFLDELESVMSQRGVG-QGGEHEGSRRMKTELLVQMDGLARSKDLVFVLAASNLPWELDHAMLRRLEKRILVGLPS 380

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Sea Lamprey
Match: trip13 (thyroid hormone receptor interactor 13 [Source:NCBI gene;Acc:393554])

HSP 1 Score: 349.362 bits (895), Expect = 1.277e-116
Identity = 194/405 (47.90%), Postives = 284/405 (70.12%), Query Frame = 3

Query:   78 LNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCD-DGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKK--IIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQID 1283
            +++EVI++  ST K E+  +H+   L++  +  + + +   D   +SFL+ +V  +S+   D +      V   K+ + +H+ QLN+     EE  + D+ N+ AA++W+LP  +F  LW+SLVY   IK +LLNY  + LLFSD ++  +VISWN+++LLHGPPGTGKTSLC+ALAQKL IRLS +Y +G +IEINSHSLFSKWFSESGKLV KM +K+ E +++++++  V+IDEVESLT  R A+ SG EPSDAIRVVN+LLTQ+D+IK Y NV +LTTSN+T  ID AF+DR DI+ +IG P+  + Y I  SCL+EL+  +   +  +DQL+S R L+ M F +T +SKSSL L ++++K  G SGR LRKLPF+AHA +++++  +++  L AL + +D
Sbjct:   19 VHVEVIQKSDSTAKMEVVVSHVMELLKRHPVVMSDMSW---DSFEDSFLQTHVRLVSITDLDLEFNHQKMVELVKTPVEVHVMQLNDDGPSMEELNQGDD-NLPAAQHWILPSTEFHGLWESLVYDSEIKLQLLNYVMTTLLFSDKNVNSNVISWNRVVLLHGPPGTGKTSLCKALAQKLCIRLSKKYRYGQLIEINSHSLFSKWFSESGKLVMKMFQKIQESIDDQEALICVLIDEVESLTASRSASHSGTEPSDAIRVVNALLTQIDQIKRYSNVIILTTSNITGKIDAAFVDRADIKQYIGPPSVMAIYQIYLSCLVELINVQCLYLPHSDQLLSFRQLEMMHFVETGMSKSSLRLHTIAEKSQGLSGRVLRKLPFIAHALYVKESTTTLSCFLDALSQAVD 419

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Sea Lamprey
Match: nvl (nuclear VCP like [Source:ZFIN;Acc:ZDB-GENE-040426-2871])

HSP 1 Score: 75.8702 bits (185), Expect = 5.595e-15
Identity = 49/161 (30.43%), Postives = 83/161 (51.55%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKS 1025
            ILL GPPG GKT L +A+A +  +      NF   I +    L + +  ES + V    +++F+   N  + C +  DE++++   R    S +E   ++RVVN LLT++D ++    VF++  +N  D +D A L   R D  +++G P       IL++
Sbjct:  295 ILLAGPPGCGKTMLAKAIANESGL------NF---ISVKGPELLNMYVGESERAV----RQVFQRARNS-APCVIFFDEIDAICPRR----SDHESGASVRVVNQLLTEMDGLEARKQVFIMAATNRPDILDRAVLRPGRLDKTLYVGLPVMAERAAILRT 437

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Sea Lamprey
Match: vcp (valosin containing protein [Source:NCBI gene;Acc:327197])

HSP 1 Score: 73.9442 bits (180), Expect = 1.017e-14
Identity = 59/204 (28.92%), Postives = 93/204 (45.59%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKS 1025
            W+ +   +++K EL       +   +      + PS     K +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES   V  +  K  +        C +  DE++S+   R   +     + A RV+N +LT++D +    NVF++  +N  D ID A L   R D  I+I  P  +S   ILK+
Sbjct:  133 WEDIGGLESVKRELQELVQYPVEHPEKFLKFGMTPS-----KGVLFYGPPGCGKTLLAKAIANEC------QANF---ISIKGPELLTMWFGESEANVRDVFDKARQAAP-----CVLFFDELDSIAKARGGNVGDGGGA-ADRVINQILTEMDGMGTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRSAILKA 316

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003236.1 (pep scaffold:Pmarinus_7.0:GL477724:37443:44438:-1 gene:ENSPMAG00000002921.1 transcript:ENSPMAT00000003236.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.3294 bits (181), Expect = 1.678e-14
Identity = 57/160 (35.62%), Postives = 79/160 (49.38%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYV-ENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIK-HYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILK 1022
            ILL GPPGTGK+ L +A+A +         N      ++S  L SKW  ES KLV    K LFE   ++K SI F  IDEV+SL G R      NE   A R+    L Q+  +      + VL  +N+   +D+A   R + RI+I  P  ++   + K
Sbjct:  166 ILLFGPPGTGKSYLAKAVATEA--------NNSTFFSVSSSDLVSKWLGESEKLV----KNLFEMARQHKPSIIF--IDEVDSLCGSRNE----NESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWTLDSAIRRRFEKRIYIPLPEEQARLSMFK 307

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Sea Lamprey
Match: katnal2 (katanin p60 subunit A-like 2 [Source:ZFIN;Acc:ZDB-GENE-051113-156])

HSP 1 Score: 74.3294 bits (181), Expect = 2.026e-14
Identity = 61/197 (30.96%), Postives = 97/197 (49.24%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPN-VFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCIL 1019
            WD ++  D  K  +       + +    +   ++S  K +LL+GPPGTGKT L +A+A +                I++ S+ SKW  +S KLV    K LFE +    +   + +DE+ES+ G R A  +G E   + R+   LL Q+D +    + VFVL  SNL   +D A L R + RI +  P+A +   ++
Sbjct:  256 WDDIIGLDAAKRLVKEAVVYPIKYP--QLFTGILSPWKGLLLYGPPGTGKTMLAKAVATECKTTF---------FNISASSIVSKWRGDSEKLV----KVLFE-LARYHAPSTIFLDELESVMGQRGAGGAGGEHEGSRRMKTELLVQMDGLARSDDLVFVLAASNLPWELDHAMLRRLEKRILVDLPSAAARRAMI 436

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Yeast
Match: PCH2 (Hexameric ring ATPase that remodels chromosome axis protein Hop1p; nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in rDNA; required for meiotic double-stranded break formation [Source:SGD;Acc:S000000390])

HSP 1 Score: 186.808 bits (473), Expect = 4.711e-53
Identity = 118/308 (38.31%), Postives = 173/308 (56.17%), Query Frame = 3

Query:  405 LPCRQFDDLWDSLVYCDNIKSELLNYAYSALLF--------SDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIR---------LSHRYNFGHMIEINSHSLFSKWFSESGK---LVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVAL 1268
            LP   F+  W+SL + +NIK  L +YA  +L          S+     ++I+ NK++L+HGPPGTGKT+LC+AL QKLS+R         +   Y  G +IE++   +FSKWF ES K   +V K +++L +  E +     ++IDEVE++   R    S NE +D IRVVN+LLTQLD++K Y N   L TSNL D++D AF+DR D   ++GNPTAE    ILK C+ E++T  II     L   R+     F      +  L   ++    +  SGRT+RKLP +  +++ R       E ++AL
Sbjct:  254 LPGTTFEGQWESLYFGNNIKERLYSYATISLKIARFKQTGDSNQEDITTLITNNKLLLVHGPPGTGKTTLCKALCQKLSVRREFSDGSDTIDTNYK-GIIIELSCARIFSKWFGESSKNISIVFKDIEELLKVNEGRGIFICLLIDEVEAIASSRTNLSSRNESTDGIRVVNTLLTQLDRLKKYHNFLALATSNLLDSLDDAFVDRADGVFYVGNPTAEGILHILKVCIEEMITSGII-----LFHARSTGVKFF---NKYQDILRKIAIKCSTVDISGRTIRKLPLMCLSEYFRTFPVDDDEFVLAL 552

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Yeast
Match: CDC48 (AAA ATPase; subunit of polyUb-selective segregase complex involved in ERAD, INM-associated degradation (INMAD), mitotic spindle disassembly, macroautophagy, PMN, ribosome-associated degradation, ribophagy, homotypic ER membrane fusion, SCF complex disassembly, cell wall integrity during heat stress, and telomerase regulation; mobilizes membrane-anchored transcription factors by regulated Ub/proteasome-dependent processing (RUP); human ortholog VCP complements a cdc48 mutant [Source:SGD;Acc:S000002284])

HSP 1 Score: 88.5817 bits (218), Expect = 5.418e-19
Identity = 69/223 (30.94%), Postives = 105/223 (47.09%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLIS 1082
            WD +   D IK EL       +L  D      + PS     K +L +GPPGTGKT L +A+A ++S       NF   I +    L S W+ ES       ++ +F+      +   V +DE++S+   R  +L G+    + RVVN LLT++D +    NVFV+  +N  D ID A L   R D  I++  P   +   IL + L     K  ++P  +L +
Sbjct:  486 WDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPS-----KGVLFYGPPGTGKTLLAKAVATEVSA------NF---ISVKGPELLSMWYGES----ESNIRDIFDKARAA-APTVVFLDELDSIAKARGGSL-GDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQL----RKTPLEPGLELTA 684

HSP 2 Score: 68.5514 bits (166), Expect = 1.106e-12
Identity = 55/177 (31.07%), Postives = 81/177 (45.76%), Query Frame = 3

Query:  498 LFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            LF    I P      + +L++GPPGTGKT + RA+A +                IN   + SK   ES       ++K FE  E K++   + IDE++S+   R       E     RVV+ LLT +D +K   NV V+  +N  ++ID A     R D  + IG P A     +L+
Sbjct:  239 LFKAIGIKPP-----RGVLMYGPPGTGKTLMARAVANETG---------AFFFLINGPEVMSKMAGES----ESNLRKAFEEAE-KNAPAIIFIDEIDSIAPKRDKTNGEVE----RRVVSQLLTLMDGMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLR 392

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Yeast
Match: RIX7 (Putative ATPase of the AAA family; required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions [Source:SGD;Acc:S000003957])

HSP 1 Score: 77.411 bits (189), Expect = 1.730e-15
Identity = 56/167 (33.53%), Postives = 82/167 (49.10%), Query Frame = 3

Query:  531 ISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKS 1025
            IS    +LL GPPG GKT L +A+A +       R NF   I I    L +K+  ES + + ++  +    V      C +  DE+++L   R  +LS      + RVVN+LLT+LD +     +FV+  +N  D ID A L   R D  +FI  P  E    I+K+
Sbjct:  564 ISAPGGVLLWGPPGCGKTLLAKAVANE------SRANF---ISIKGPELLNKYVGESERSIRQVFTRARASVP-----CVIFFDELDALVPRRDTSLS----ESSSRVVNTLLTELDGLNDRRGIFVIGATNRPDMIDPAMLRPGRLDKSLFIELPNTEEKLDIIKT 712

HSP 2 Score: 60.8474 bits (146), Expect = 3.333e-10
Identity = 58/205 (28.29%), Postives = 94/205 (45.85%), Query Frame = 3

Query:  438 SLVYCDNIKSELLNYAYSALL----FSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKI----KHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            SL   D++ ++L+      +L    F  T + P      + +LLHGPPG GKTS+  ALA +L +           I I++ S+ S    ES     K ++ LF+   +  + C V  DE++++T  R     G +     R+V  LLT +D++     +   V ++  +N  D++D A     R D  I +  P   S   ILK
Sbjct:  206 SLGGMDDVVAQLMELIGLPILHPEIFLSTGVEPP-----RGVLLHGPPGCGKTSIANALAGELQV---------PFISISAPSVVSGMSGES----EKKIRDLFDEARSL-APCLVFFDEIDAITPKRDG---GAQREMERRIVAQLLTSMDELTMEKTNGKPVIIIGATNRPDSLDAALRRAGRFDREICLNVPNEVSRLHILK 388

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Yeast
Match: VPS4 (AAA-ATPase involved in multivesicular body (MVB) protein sorting; ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism [Source:SGD;Acc:S000006377])

HSP 1 Score: 75.8702 bits (185), Expect = 2.627e-15
Identity = 58/151 (38.41%), Postives = 82/151 (54.30%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYV-ENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNS-LLTQLDKIKH-YPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNP 992
            ILL+GPPGTGK+ L +A+A + +              ++S  L SKW  ES KLV    K+LF    ENK SI F  IDEV++LTG R     G   S+A R + + LL Q++ + +    V VL  +N+   +D+A   R + RI+I  P
Sbjct:  169 ILLYGPPGTGKSYLAKAVATEAN---------STFFSVSSSDLVSKWMGESEKLV----KQLFAMARENKPSIIF--IDEVDALTGTR-----GEGESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDSAIRRRFERRIYIPLP 299

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Yeast
Match: MSP1 (Highly-conserved N-terminally anchored AAA-ATPase; distributed in the mitochondrial outer membrane and peroxisomes; involved in mitochondrial protein sorting; functions as an extraction engine in local organelle surveillance to remove and initiate degradation of mistargeted proteins, ensuring fidelity of organelle-specific localization of tail-anchored proteins; contains an N-terminal transmembrane domain and C-terminal cytoplasmic ATPase domain [Source:SGD;Acc:S000003260])

HSP 1 Score: 72.4034 bits (176), Expect = 2.787e-14
Identity = 48/161 (29.81%), Postives = 80/161 (49.69%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCL 1031
            +LL+GPPG GKT L +ALA++         +  + I I   S+  KW+ ES K+V  M       + NK   C + IDE++S   +R+ + + +E +  ++     +T  D + +   V ++  +N  + ID AFL R   R  +  P ++  Y IL   L
Sbjct:  129 VLLYGPPGCGKTMLAKALAKE---------SGANFISIRMSSIMDKWYGESNKIVDAMFS-----LANKLQPCIIFIDEIDSF--LRERSSTDHEVTATLKA--EFMTLWDGLLNNGRVMIIGATNRINDIDDAFLRRLPKRFLVSLPGSDQRYKILSVLL 271

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Nematostella
Match: EDO30919 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZE7])

HSP 1 Score: 313.538 bits (802), Expect = 1.880e-103
Identity = 158/324 (48.77%), Postives = 229/324 (70.68%), Query Frame = 3

Query:   81 NIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDG---VESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELM 1043
            ++EV ++  ST      ++++  +L  +  ++    F   +   N FL +++ SIS+  CD     VE  +++     L IH++QL++     EE  +     I AA +W+LP  +F+ +WDSLV+  ++K++L+NYA + LLFSD  +  ++I+WN++ILLHGPPGTGKTSLC+ALAQKL +RLS RY++G +IEINSHSLFSKWFSESGKLV KM +K+ E +++K+++  V+IDEVESLT  R+AA+ G EPSDAIRVVN+LLTQ+D+IK +PNV +LTTSN+T AID AF+DR DI+ +IG P+  + Y I  SC+ ELM
Sbjct:   20 HVEVCQQPCSTALPNTLKDYVKQFLICIGTAYGDTTF---NHFENEFLNEHIKSISI--CDTDLVLVERKAIDLQSCKLAIHVFQLHDDGPASEELED----EITAANHWLLPAAEFEGIWDSLVFDTDVKAQLINYATTTLLFSDRGVNANIITWNRVILLHGPPGTGKTSLCKALAQKLCVRLSDRYSYGQLIEINSHSLFSKWFSESGKLVMKMFQKIQELIDDKEALVCVLIDEVESLTAARKAAMQGQEPSDAIRVVNALLTQIDQIKRHPNVIILTTSNVTGAIDLAFVDRADIKQYIGPPSVNAIYTIYHSCINELM 334

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Nematostella
Match: EDO35907 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK75])

HSP 1 Score: 81.2629 bits (199), Expect = 1.497e-16
Identity = 65/166 (39.16%), Postives = 86/166 (51.81%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYV-ENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIK-HYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIEL 1040
            ILL+GPPGTGK+ L +A+A +         N    I ++S  L SKW  ES +LV    K+LFE   ENK SI F  IDEV+SL G R    S NE   A R+    L Q+  +      V VL  +N+   +D+A   R + RI+I  P  E A    +S + EL
Sbjct:  168 ILLYGPPGTGKSYLAKAVATEA--------NNSTFISVSSSDLVSKWLGESERLV----KQLFELARENKPSIIF--IDEVDSLCGSR----SENESESARRIKTEFLVQMQGVGVDNDQVLVLGATNIPWTLDSAIRRRFEKRIYI--PLPEQA---ARSKMFEL 310

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Nematostella
Match: EDO36214 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJD2])

HSP 1 Score: 79.7221 bits (195), Expect = 2.101e-16
Identity = 63/201 (31.34%), Postives = 97/201 (48.26%), Query Frame = 3

Query:  423 DDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVE-NKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPN-VFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCIL 1019
            D  WD ++  D  K  +       + +    +   ++S  K +LL+GPPGTGKT L +A+A + +              I++ S+ SKW  +S KLV    + LFE    +  S  F  +DE+ESL   R     G E   ++R+   LL Q+D +    + VF+L  SNL   +D A L R + RI +  PT E+   +L
Sbjct:   33 DVRWDDIIGLDAAKRLVKEAVVYPIKYP--QLFTGILSPWKGLLLYGPPGTGKTLLAKAVATECNTTF---------FNISASSIVSKWRGDSEKLV----RVLFELARFHAPSTIF--LDELESLMSQRGTGGGGAEHEGSLRMKTELLVQMDGLARSDDLVFLLAASNLPWELDHAMLRRLEKRILVDLPTLEARKAML 216

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Nematostella
Match: EDO36218 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ61])

HSP 1 Score: 75.0998 bits (183), Expect = 2.726e-14
Identity = 62/206 (30.10%), Postives = 95/206 (46.12%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            WD +   + +K EL       +   D      + PS     K +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES   V    + +F+   +  + C +  DE++S+   R   +     + A RV+N +LT++D +    NVF++  +N  D ID A L   R D  I+I  P   S   ILK+ L
Sbjct:  471 WDDIGGLEGVKRELQELVQYPVEHPDKFLKFGMTPS-----KGVLFYGPPGCGKTLLAKAIANEC------QANF---ISIKGPELLTMWFGESEANV----RDVFDKARSA-APCVLFFDELDSIAKSRGGNVGDGGGA-ADRVINQVLTEMDGMNVKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDGSRSSILKANL 656

HSP 2 Score: 67.0106 bits (162), Expect = 9.265e-12
Identity = 51/160 (31.87%), Postives = 75/160 (46.88%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            ILL GPPGTGKT + RA+A +                IN   + SK   ES       ++K FE  E K+S   + IDE++++   R       E     R+V+ LLT +D +K   +V V+  +N  +++D A     R D  + IG P A     IL+
Sbjct:  236 ILLFGPPGTGKTLMARAVANETG---------AFFFLINGPEIMSKLAGES----ESNLRKAFEEAE-KNSPAIIFIDEIDAIAPKRDKTHGEVE----RRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDVALRRFGRFDREVDIGIPDATGRLEILR 377

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Nematostella
Match: EDO49524 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGH4])

HSP 1 Score: 73.559 bits (179), Expect = 3.966e-14
Identity = 56/167 (33.53%), Postives = 83/167 (49.70%), Query Frame = 3

Query:  531 ISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYV-ENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILK 1022
            I   K +LL+GPPGTGKT L RA+A          +     I ++   L  K+  E     A+M+++LF    E+  SI F  +DE++S+   R    SG + S+  R +  LL QLD  +   N+ V+  +N  D +D+A L   R D +I    P  E+   ILK
Sbjct:  172 IDQPKGVLLYGPPGTGKTLLARAVAH---------HTECTFIRVSGSELVQKFIGEG----ARMVRELFVMAREHAPSIIF--MDEIDSIGSSRLEGGSGGD-SEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARQDILK 322

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BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Medaka
Match: trip13 (thyroid hormone receptor interactor 13 [Source:NCBI gene;Acc:101161993])

HSP 1 Score: 338.191 bits (866), Expect = 4.881e-111
Identity = 185/409 (45.23%), Postives = 275/409 (67.24%), Query Frame = 3

Query:   72 RELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQIDYLKLE 1298
            +++N+EV  +  ST K    +  +   L +    F   ++ + D   + FL ++V S+S++  ++ + +  ++    ++ I+++      +     L  + E + AA +W+LP  +F  +W+SLVY   IKS+LL+Y  + + FSD ++  ++ISWN+++LLHGPPGTGKTSLC+ALAQKLSIRLS RY++G  IEINSHSLFSKWFSESGKLV KM +K+ E +++K+++ FV+IDEVESLT  R A+ +G EPSDAIRVVNS+LTQLD+IK + NV +LTTSN+T+ ID AF+DR DI+ +IG P+ +  Y I  SCL ELM  +II P   L +   L+ M FA++++S+ SL L  ++KK  G SGR LRKLPFLAHA F++    ++ + L A+   +D  + E
Sbjct:   61 QKINVEVHVKSLSTAKMSEVKTRVQTLLNRHRTVFGNYRWTEFD---DEFLSRHVESVSILDLEEMM-AQPLDLKSCAVSIYIF---TLNEDGPSMLSLEEEELSAANHWLLPAAEFHGIWESLVYETGIKSKLLDYVTTTIYFSDKNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLSIRLSDRYSYGQFIEINSHSLFSKWFSESGKLVTKMFQKIQELIDDKEALVFVLIDEVESLTAARNASQAGTEPSDAIRVVNSVLTQLDQIKRHSNVVILTTSNVTEKIDLAFVDRADIKQYIGPPSEKGIYNIFLSCLEELMKCQIICPRQPLFTMYELETMCFANSEVSEHSLRLMDIAKKSKGLSGRALRKLPFLAHALFVKTPAVTLDQFLDAMSHAVDKQREE 462

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Medaka
Match: trip13 (thyroid hormone receptor interactor 13 [Source:NCBI gene;Acc:101161993])

HSP 1 Score: 301.982 bits (772), Expect = 8.407e-98
Identity = 143/244 (58.61%), Postives = 189/244 (77.46%), Query Frame = 3

Query:  387 AAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADT 1118
            AA +W+LP  +F  +W+SLVY   IKS+LL+Y  + + FSD ++  ++ISWN+++LLHGPPGTGKTSLC+ALAQKLSIRLS RY++G  IEINSHSLFSKWFSESGKLV KM +K+ E +++K+++ FV+IDEVESLT  R A+ +G EPSDAIRVVNS+LTQLD+IK + NV +LTTSN+T+ ID AF+DR DI+ +IG P+ +  Y I  SCL ELM  +II P   L +   L+ M FA++
Sbjct:  104 AANHWLLPAAEFHGIWESLVYETGIKSKLLDYVTTTIYFSDKNVDSNLISWNRVVLLHGPPGTGKTSLCKALAQKLSIRLSDRYSYGQFIEINSHSLFSKWFSESGKLVTKMFQKIQELIDDKEALVFVLIDEVESLTAARNASQAGTEPSDAIRVVNSVLTQLDQIKRHSNVVILTTSNVTEKIDLAFVDRADIKQYIGPPSEKGIYNIFLSCLEELMKCQIICPRQPLFTMYELETMCFANS 347

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Medaka
Match: katnal2 (katanin catalytic subunit A1 like 2 [Source:NCBI gene;Acc:101168474])

HSP 1 Score: 82.0333 bits (201), Expect = 9.627e-17
Identity = 60/173 (34.68%), Postives = 92/173 (53.18%), Query Frame = 3

Query:  525 SVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPN-VFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIEL 1040
             ++S  K +LL+GPPGTGKT L +A+A +       R  F     I++ S+ SKW  +S KLV    + LFE +    +   + +DE+ES+ G R  +L G E   + R+   LL Q+D +    + VFVL  SNL   +D A L R + RI +G P++ +   ++   L  L
Sbjct:   86 GILSPWKGLLLYGPPGTGKTLLAKAVATEC------RTTF---FNISASSIVSKWRGDSEKLV----RVLFE-LARYHAPSTIFLDELESVMGQRGTSL-GGEHEGSRRMKTELLVQMDGLSRSEDLVFVLAASNLPWELDHAMLRRLEKRILVGLPSSPARQAMISHWLPPL 243

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Medaka
Match: katnal2 (katanin catalytic subunit A1 like 2 [Source:NCBI gene;Acc:101168474])

HSP 1 Score: 81.6481 bits (200), Expect = 3.102e-16
Identity = 60/173 (34.68%), Postives = 92/173 (53.18%), Query Frame = 3

Query:  525 SVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPN-VFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIEL 1040
             ++S  K +LL+GPPGTGKT L +A+A +       R  F     I++ S+ SKW  +S KLV    + LFE +    +   + +DE+ES+ G R  +L G E   + R+   LL Q+D +    + VFVL  SNL   +D A L R + RI +G P++ +   ++   L  L
Sbjct:  230 GILSPWKGLLLYGPPGTGKTLLAKAVATEC------RTTF---FNISASSIVSKWRGDSEKLV----RVLFE-LARYHAPSTIFLDELESVMGQRGTSL-GGEHEGSRRMKTELLVQMDGLSRSEDLVFVLAASNLPWELDHAMLRRLEKRILVGLPSSPARQAMISHWLPPL 387

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Medaka
Match: vcp (valosin containing protein [Source:NCBI gene;Acc:101174924])

HSP 1 Score: 79.7221 bits (195), Expect = 2.392e-15
Identity = 62/206 (30.10%), Postives = 96/206 (46.60%), Query Frame = 3

Query:  432 WDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            WD +   +++K EL       +   D      + PS     K +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES   V ++  K  +      + C +  DE++S+   R   +     + A RV+N +LT++D +    NVF++  +N  D ID A L   R D  I+I  P  +S   ILK+ L
Sbjct:  484 WDDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPS-----KGVLFYGPPGCGKTLLAKAIANEC------QANF---ISIKGPELLTMWFGESEANVREIFDKARQA-----APCVLFFDELDSIAKARGGNVGDGGGA-ADRVINQILTEMDGMSSKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRISILKANL 669

HSP 2 Score: 67.3958 bits (163), Expect = 2.165e-11
Identity = 51/160 (31.87%), Postives = 77/160 (48.12%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            ILL+GPPGTGKT + RA+A +                IN   + SK   ES       ++K FE  E K++   + IDE++++   R+      E     R+V+ LLT +D +K   +V V+  +N  ++ID A     R D  + IG P A     IL+
Sbjct:  249 ILLYGPPGTGKTLIARAVANETG---------AFFFLINGPEIMSKLAGES----ESNLRKAFEEAE-KNAPAIIFIDELDAIAPKREKTHGEVE----RRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQ 390

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Planmine SMEST
Match: SMESG000040170.1 (SMESG000040170.1)

HSP 1 Score: 801.586 bits (2069), Expect = 0.000e+0
Identity = 430/433 (99.31%), Postives = 431/433 (99.54%), Query Frame = 3

Query:   24 MSDNDSNMEMISDNFSRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTXXXXXXXXXXXXXXXXXGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQIDYLKLEARFIENLS 1322
            MSDNDSNMEM SDNFSRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDF NNSFL+KNVVSISVIYCDDGVESGSVNFNKSSLHIHLYQLNETEDYYEEELEHDNENIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTKISKSSLGLWSLSKKCLGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQIDYLKLEARFIENLS
Sbjct:    1 MSDNDSNMEMTSDNFSRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFMNNSFLEKNVVSISVIYCDDGVESGSVNFNKSSLHIHLYQLNETEDYYEEELEHDNENIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADTKISKSSLGLWSLSKKCLGFSGRTLRKLPFLAHAKFIRKNVCSITEVLVALDKQIDYLKLEARFIENLS 433

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Planmine SMEST
Match: SMESG000040170.1 (SMESG000040170.1)

HSP 1 Score: 703.36 bits (1814), Expect = 0.000e+0
Identity = 362/365 (99.18%), Postives = 363/365 (99.45%), Query Frame = 3

Query:   24 MSDNDSNMEMISDNFSRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGVESGSVNFNKSSLHIHLYQXXXXXXXXXXXXXXXXXNIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADT 1118
            MSDNDSNMEM SDNFSRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDF NNSFL+KNVVSISVIYCDDGVESGSVNFNKSSLHIHLYQLNETEDYYEEELEHDNENIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADT
Sbjct:    1 MSDNDSNMEMTSDNFSRELNIEVIKEKSSTVKREIFENHIFLYLQQVNISFAPIKFLKEDFMNNSFLEKNVVSISVIYCDDGVESGSVNFNKSSLHIHLYQLNETEDYYEEELEHDNENIIAAENWMLPCRQFDDLWDSLVYCDNIKSELLNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQLISQRALDYMEFADT 365

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Planmine SMEST
Match: SMESG000016085.1 (SMESG000016085.1)

HSP 1 Score: 85.8853 bits (211), Expect = 2.233e-17
Identity = 67/208 (32.21%), Postives = 101/208 (48.56%), Query Frame = 3

Query:  429 LWDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALS-GNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            LW  +   DN+K EL       +   D      + PS     K +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES       +++LF+    + + C +  DE++S+   R ++ S G   SD  RV+N LLT++D +    NVF++  +N  D ID+A L   R D  I+I  P  +S   I K+ L
Sbjct:  473 LWSDVGGLDNVKKELQELVQYPVEHPDKFLKFGMTPS-----KGVLFYGPPGCGKTLLAKAIASEC------QANF---ISIKGPELLTMWFGES----EANIRELFDKA-RQAAPCILFFDELDSIAKSRGSSASDGGGASD--RVINQLLTEMDGMSLKKNVFIIGATNRPDIIDSAILRPGRLDQLIYIPLPDEKSRIQIFKAAL 659

HSP 2 Score: 67.3958 bits (163), Expect = 1.392e-11
Identity = 51/160 (31.87%), Postives = 78/160 (48.75%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            ILL+GPPGTGKT + RA+A +                IN   + SK   ES       ++K FE  E K+S   + IDE++++   R+      E     R+V+ LLT +D +K   +V V+  +N  ++ID+A     R D  + IG P +     IL+
Sbjct:  239 ILLYGPPGTGKTLIARAVANETG---------SFFFLINGPEIMSKLAGES----ESNLRKAFEEAE-KNSPAIIFIDEIDAIAPKREKTQGEVE----RRIVSQLLTLMDGLKQRSHVVVMAATNRPNSIDSALRRFGRFDREVDIGIPDSIGRLEILR 380

[Close]

BLAST of Pachytene checkpoint protein 2 homolog vs. Planmine SMEST
Match: SMESG000016085.1 (SMESG000016085.1)

HSP 1 Score: 85.5001 bits (210), Expect = 2.504e-17
Identity = 67/208 (32.21%), Postives = 101/208 (48.56%), Query Frame = 3

Query:  429 LWDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALS-GNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            LW  +   DN+K EL       +   D      + PS     K +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES       +++LF+    + + C +  DE++S+   R ++ S G   SD  RV+N LLT++D +    NVF++  +N  D ID+A L   R D  I+I  P  +S   I K+ L
Sbjct:  484 LWSDVGGLDNVKKELQELVQYPVEHPDKFLKFGMTPS-----KGVLFYGPPGCGKTLLAKAIASEC------QANF---ISIKGPELLTMWFGES----EANIRELFDKA-RQAAPCILFFDELDSIAKSRGSSASDGGGASD--RVINQLLTEMDGMSLKKNVFIIGATNRPDIIDSAILRPGRLDQLIYIPLPDEKSRIQIFKAAL 670

HSP 2 Score: 67.3958 bits (163), Expect = 1.330e-11
Identity = 51/160 (31.87%), Postives = 78/160 (48.75%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            ILL+GPPGTGKT + RA+A +                IN   + SK   ES       ++K FE  E K+S   + IDE++++   R+      E     R+V+ LLT +D +K   +V V+  +N  ++ID+A     R D  + IG P +     IL+
Sbjct:  250 ILLYGPPGTGKTLIARAVANETG---------SFFFLINGPEIMSKLAGES----ESNLRKAFEEAE-KNSPAIIFIDEIDAIAPKREKTQGEVE----RRIVSQLLTLMDGLKQRSHVVVMAATNRPNSIDSALRRFGRFDREVDIGIPDSIGRLEILR 391

[Close]

Query:  429 LWDSLVYCDNIKSELLNYAYSALLFSDT----SICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALS-GNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAFL--DRTDIRIFIGNPTAESAYCILKSCL 1031
            LW  +   DN+K EL       +   D      + PS     K +L +GPPG GKT L +A+A +       + NF   I I    L + WF ES       +++LF+    + + C +  DE++S+   R ++ S G   SD  RV+N LLT++D +    NVF++  +N  D ID+A L   R D  I+I  P  +S   I K+ L
Sbjct:  484 LWSDVGGLDNVKKELQELVQYPVEHPDKFLKFGMTPS-----KGVLFYGPPGCGKTLLAKAIASEC------QANF---ISIKGPELLTMWFGES----EANIRELFDKA-RQAAPCILFFDELDSIAKSRGSSASDGGGASD--RVINQLLTEMDGMSLKKNVFIIGATNRPDIIDSAILRPGRLDQLIYIPLPDEKSRIQIFKAAL 670

HSP 2 Score: 67.3958 bits (163), Expect = 1.365e-11
Identity = 51/160 (31.87%), Postives = 78/160 (48.75%), Query Frame = 3

Query:  549 ILLHGPPGTGKTSLCRALAQKLSIRLSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFVIIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTSNLTDAIDTAF--LDRTDIRIFIGNPTAESAYCILK 1022
            ILL+GPPGTGKT + RA+A +                IN   + SK   ES       ++K FE  E K+S   + IDE++++   R+      E     R+V+ LLT +D +K   +V V+  +N  ++ID+A     R D  + IG P +     IL+
Sbjct:  250 ILLYGPPGTGKTLIARAVANETG---------SFFFLINGPEIMSKLAGES----ESNLRKAFEEAE-KNSPAIIFIDEIDAIAPKREKTQGEVE----RRIVSQLLTLMDGLKQRSHVVVMAATNRPNSIDSALRRFGRFDREVDIGIPDSIGRLEILR 391

The following BLAST results are available for this feature:

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Human
BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Celegans
BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Fly
BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Zebrafish
BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Xenopus
BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Mouse
BLAST of Pachytene checkpoint protein 2 homolog vs. UniProt/SwissProt
BLAST of Pachytene checkpoint protein 2 homolog vs. TrEMBL
BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Cavefish
BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Sea Lamprey
BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Yeast
BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Nematostella
BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Medaka
BLAST of Pachytene checkpoint protein 2 homolog vs. Planmine SMEST

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TRIP13	4.356e-120	48.93	thyroid hormone receptor interactor 13 [Source:HGN...	[more]
TRIP13	3.186e-62	48.90	thyroid hormone receptor interactor 13 [Source:HGN...	[more]
NVL	2.063e-15	29.00	nuclear VCP like [Source:HGNC Symbol;Acc:HGNC:8070...	[more]
NVL	2.295e-15	29.00	nuclear VCP like [Source:HGNC Symbol;Acc:HGNC:8070...	[more]
NVL	2.295e-15	29.00	nuclear VCP like [Source:HGNC Symbol;Acc:HGNC:8070...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pch-2	6.625e-67	43.51	Putative pachytene checkpoint protein 2 [Source:U...	[more]
rpt-4	1.583e-15	33.33	Probable 26S proteasome regulatory subunit 10B [S...	[more]
rpt-4	1.665e-15	33.33	Probable 26S proteasome regulatory subunit 10B [S...	[more]
cdc-48.2	2.917e-14	29.13	Transitional endoplasmic reticulum ATPase homolog ...	[more]
cdc-48.2	2.917e-14	29.13	Transitional endoplasmic reticulum ATPase homolog ...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pch2	2.416e-88	48.50	gene:FBgn0051453 transcript:FBtr0339330	[more]
pch2	2.416e-88	48.50	gene:FBgn0051453 transcript:FBtr0081898	[more]
CG10793	3.717e-15	33.95	gene:FBgn0029656 transcript:FBtr0070536	[more]
smid	5.257e-15	29.67	gene:FBgn0016983 transcript:FBtr0076851	[more]
smid	5.259e-15	29.67	gene:FBgn0016983 transcript:FBtr0331850	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trip13	8.407e-114	45.41	thyroid hormone receptor interactor 13 [Source:NCB...	[more]
trip13	6.187e-43	41.83	thyroid hormone receptor interactor 13 [Source:NCB...	[more]
vcp	1.698e-15	30.10	valosin containing protein [Source:NCBI gene;Acc:3...	[more]
vcp	1.886e-15	30.10	valosin containing protein [Source:NCBI gene;Acc:3...	[more]
nvl	2.335e-14	31.68	nuclear VCP like [Source:ZFIN;Acc:ZDB-GENE-040426-...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
myo6	1.309e-116	47.52	myosin VI [Source:Xenbase;Acc:XB-GENE-1012303]	[more]
myo6	7.693e-116	47.65	myosin VI [Source:Xenbase;Acc:XB-GENE-1012303]	[more]
myo6	1.515e-114	49.35	myosin VI [Source:Xenbase;Acc:XB-GENE-1012303]	[more]
myo6	4.578e-113	50.41	myosin VI [Source:Xenbase;Acc:XB-GENE-1012303]	[more]
myo6	5.874e-113	50.41	myosin VI [Source:Xenbase;Acc:XB-GENE-1012303]	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Trip13	7.266e-120	48.03	thyroid hormone receptor interactor 13 [Source:MGI...	[more]
Nvl	1.419e-15	34.16	nuclear VCP-like [Source:MGI Symbol;Acc:MGI:191470...	[more]
Vcp	8.496e-15	29.61	valosin containing protein [Source:MGI Symbol;Acc:...	[more]
Vps4b	9.698e-15	36.88	vacuolar protein sorting 4B [Source:MGI Symbol;Acc...	[more]
Vps4b	9.698e-15	36.88	vacuolar protein sorting 4B [Source:MGI Symbol;Acc...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|E1C6Q1\|PCH2_CHICK	1.717e-122	49.15	Pachytene checkpoint protein 2 homolog OS=Gallus g...	[more]
sp\|Q15645\|PCH2_HUMAN	2.092e-119	48.93	Pachytene checkpoint protein 2 homolog OS=Homo sap...	[more]
sp\|Q5XHZ9\|PCH2_RAT	2.597e-119	48.28	Pachytene checkpoint protein 2 homolog OS=Rattus n...	[more]
sp\|Q3UA06\|PCH2_MOUSE	5.082e-119	48.03	Pachytene checkpoint protein 2 homolog OS=Mus musc...	[more]
sp\|D3K5L7\|PCH2_PIG	2.061e-117	48.39	Pachytene checkpoint protein 2 homolog OS=Sus scro...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
V5SKQ2	1.412e-124	48.10	Pachytene checkpoint 2-like protein OS=Nodipecten ...	[more]
A0A210PWC5	1.626e-124	49.75	Pachytene checkpoint protein 2-like OS=Mizuhopecte...	[more]
A0A1S3H9M9	3.611e-123	48.58	pachytene checkpoint protein 2 homolog OS=Lingula ...	[more]
A0A1S3KC13	8.503e-123	49.63	pachytene checkpoint protein 2 homolog OS=Lingula ...	[more]
A0A1V4JVF1	1.713e-121	49.51	Pachytene checkpoint 2-like protein OS=Patagioenas...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trip13	2.368e-103	43.69	thyroid hormone receptor interactor 13 [Source:NCB...	[more]
nvl	2.290e-16	30.35	nuclear VCP like [Source:NCBI gene;Acc:103033742]	[more]
nvl	2.290e-16	30.35	nuclear VCP like [Source:NCBI gene;Acc:103033742]	[more]
zgc:136908	4.409e-14	28.64	zgc:136908 [Source:ZFIN;Acc:ZDB-GENE-060312-22]	[more]
katnal2	4.685e-14	34.18	katanin catalytic subunit A1 like 2 [Source:NCBI g...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trip13	1.277e-116	47.90	thyroid hormone receptor interactor 13 [Source:NCB...	[more]
nvl	5.595e-15	30.43	nuclear VCP like [Source:ZFIN;Acc:ZDB-GENE-040426-...	[more]
vcp	1.017e-14	28.92	valosin containing protein [Source:NCBI gene;Acc:3...	[more]
ENSPMAT00000003236.1	1.678e-14	35.63	pep scaffold:Pmarinus_7.0:GL477724:37443:44438:-1 ...	[more]
katnal2	2.026e-14	30.96	katanin p60 subunit A-like 2 [Source:ZFIN;Acc:ZDB-...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
PCH2	4.711e-53	38.31	Hexameric ring ATPase that remodels chromosome axi...	[more]
CDC48	5.418e-19	30.94	AAA ATPase; subunit of polyUb-selective segregase ...	[more]
RIX7	1.730e-15	33.53	Putative ATPase of the AAA family; required for ex...	[more]
VPS4	2.627e-15	38.41	AAA-ATPase involved in multivesicular body (MVB) p...	[more]
MSP1	2.787e-14	29.81	Highly-conserved N-terminally anchored AAA-ATPase;...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO30919	1.880e-103	48.77	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35907	1.497e-16	39.16	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36214	2.101e-16	31.34	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36218	2.726e-14	30.10	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49524	3.966e-14	33.53	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trip13	4.881e-111	45.23	thyroid hormone receptor interactor 13 [Source:NCB...	[more]
trip13	8.407e-98	58.61	thyroid hormone receptor interactor 13 [Source:NCB...	[more]
katnal2	9.627e-17	34.68	katanin catalytic subunit A1 like 2 [Source:NCBI g...	[more]
katnal2	3.102e-16	34.68	katanin catalytic subunit A1 like 2 [Source:NCBI g...	[more]
vcp	2.392e-15	30.10	valosin containing protein [Source:NCBI gene;Acc:1...	[more]

BLAST of Pachytene checkpoint protein 2 homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000040170.1	0.000e+0	99.31	SMESG000040170.1	[more]
SMESG000040170.1	0.000e+0	99.18	SMESG000040170.1	[more]
SMESG000016085.1	2.233e-17	32.21	SMESG000016085.1	[more]
SMESG000016085.1	2.504e-17	32.21	SMESG000016085.1	[more]
SMESG000016085.1	2.504e-17	32.21	SMESG000016085.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30024431 ID=SMED30024431|Name=Pachytene checkpoint protein 2 homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=1523bp
TTAAAAATTTATTCTAATTGAAAATGTCAGATAATGATAGCAATATGGAA
ATGATATCAGATAACTTTTCTAGAGAATTAAATATTGAAGTTATTAAAGA
AAAATCAAGCACTGTTAAACGAGAAATATTTGAAAATCATATTTTTTTGT
ATTTGCAACAAGTTAATATTAGTTTTGCTCCAATAAAATTTCTGAAAGAA
GATTTTAAGAATAATTCGTTTTTGAAAAAAAATGTTGTTTCTATTTCTGT
GATATATTGTGATGATGGAGTTGAAAGTGGTTCGGTTAATTTCAATAAAT
CCTCCTTGCATATCCATTTATATCAATTAAATGAAACAGAAGATTATTAC
GAAGAAGAACTTGAACACGATAACGAGAATATAATAGCCGCTGAAAATTG
GATGCTACCATGCAGACAATTTGACGATTTGTGGGATTCGCTTGTATATT
GCGATAATATCAAAAGTGAATTGCTAAATTATGCATATAGTGCACTGTTA
TTTAGCGATACGTCGATTTGCCCCTCGGTTATTTCTTGGAATAAAATAAT
ATTGTTACATGGGCCACCTGGAACCGGCAAAACATCATTGTGTCGTGCAT
TGGCACAGAAGTTATCTATTCGACTGTCTCACCGTTATAATTTTGGTCAC
ATGATCGAAATCAATAGTCATAGTCTGTTTTCCAAATGGTTCAGCGAAAG
CGGGAAATTAGTGGCAAAAATGATGAAGAAACTTTTTGAATATGTTGAAA
ACAAAGATTCGATTTGCTTTGTTATCATAGACGAAGTGGAAAGTCTAACC
GGAGTGCGTCAGGCCGCGTTATCTGGAAATGAACCGTCTGATGCGATCCG
GGTAGTTAATTCTCTGCTGACCCAGCTGGATAAAATTAAACATTATCCCA
ATGTATTCGTGTTAACGACCTCTAATCTAACCGATGCCATTGACACCGCC
TTCCTCGACAGGACCGATATTCGCATCTTTATCGGAAATCCTACTGCTGA
ATCTGCATATTGCATTTTAAAATCGTGTTTAATTGAGCTTATGACAAAGA
AGATAATCCAGCCTGCTGATCAGTTGATAAGTCAGCGTGCATTGGACTAT
ATGGAATTCGCCGATACTAAGATCTCGAAATCAAGTCTCGGATTATGGAG
TTTGTCGAAAAAATGTTTAGGTTTTAGTGGACGAACTTTGAGAAAACTTC
CATTTTTAGCCCATGCAAAATTTATAAGGAAAAACGTTTGTTCAATTACC
GAAGTTTTAGTTGCTTTGGATAAACAAATCGATTATTTGAAATTAGAAGC
TCGTTTCATAGAAAATCTGAGTTAATTTTAATTGGATATTTCGTATAATA
TAATTCGTTTTGTTCCGTTTTCAATATGATTTATTACTACAAATTCAACT
TTTATAATTATTATTGTCAATAGTTTCTTATAAAATCATTTTCCATCCGA
ATTTATAATAACTTTTATAAATTTTATTTATTCCTTCTGATCAGTCGTTT
AGCATCGAAGATTGTAATATTGG

protein sequence of SMED30024431-orf-1

>SMED30024431-orf-1 ID=SMED30024431-orf-1|Name=SMED30024431-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=434bp
MSDNDSNMEMISDNFSRELNIEVIKEKSSTVKREIFENHIFLYLQQVNIS
FAPIKFLKEDFKNNSFLKKNVVSISVIYCDDGVESGSVNFNKSSLHIHLY
QLNETEDYYEEELEHDNENIIAAENWMLPCRQFDDLWDSLVYCDNIKSEL
LNYAYSALLFSDTSICPSVISWNKIILLHGPPGTGKTSLCRALAQKLSIR
LSHRYNFGHMIEINSHSLFSKWFSESGKLVAKMMKKLFEYVENKDSICFV
IIDEVESLTGVRQAALSGNEPSDAIRVVNSLLTQLDKIKHYPNVFVLTTS
NLTDAIDTAFLDRTDIRIFIGNPTAESAYCILKSCLIELMTKKIIQPADQ
LISQRALDYMEFADTKISKSSLGLWSLSKKCLGFSGRTLRKLPFLAHAKF
IRKNVCSITEVLVALDKQIDYLKLEARFIENLS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell
PLANA:0002142	parenchyma
PLANA:0003304	testis primordium

Vocabulary: **INTERPRO**
Term	Definition
IPR001270	ClpA/B
IPR003593	AAA+_ATPase
IPR027417	P-loop_NTPase
IPR003959	ATPase_AAA_core
IPR003960	ATPase_AAA_CS

Vocabulary: **molecular function**
Term	Definition
GO:0005524	ATP binding
GO:0000166	nucleotide binding

Vocabulary: **biological process**
Term	Definition
GO:0006302	double-strand break repair
GO:0007130	synaptonemal complex assembly
GO:0007131	reciprocal meiotic recombination
GO:0007283	spermatogenesis
GO:0030154	cell differentiation
GO:0048477	oogenesis
GO:0051321	meiotic cell cycle

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 429..433
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 113..343 e-value: 2.3E-40 score: 140.1
None	No IPR available	PANTHER	PTHR45991	FAMILY NOT NAMED	coord: 5..421
None	No IPR available	CDD	cd00009	AAA	coord: 174..321 e-value: 1.37104E-17 score: 77.5715
IPR001270	ClpA/B family	PRINTS	PR00300	CLPPROTEASEA	coord: 290..304 score: 29.94 coord: 176..194 score: 53.08
IPR003593	AAA+ ATPase domain	SMART	SM00382	AAA_5	coord: 172..324 e-value: 2.7E-14 score: 63.5
IPR003959	ATPase, AAA-type, core	PFAM	PF00004	AAA	coord: 176..321 e-value: 8.3E-32 score: 110.4
IPR003960	ATPase, AAA-type, conserved site	PROSITE	PS00674	AAA	coord: 294..313
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 136..411