Protein kinase domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024411 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: NEK5 (NIMA related kinase 5 [Source:HGNC Symbol;Acc:HGNC:7748]) HSP 1 Score: 111.309 bits (277), Expect = 2.438e-26 Identity = 80/258 (31.01%), Postives = 128/258 (49.61%), Query Frame = 3
Query: 1311 MEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCSLY------RDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQ--NEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGN-PKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMP-ISDGLHQFINSCLTVDPSERPS 2054
M+ ++ ++ G+GAFG L + + ++K++N K + ++ + K+ N++ + + + M Y GG L K I + R +E+ I QI + +H +I+HRDIK NI L + G KL DFG+ AR+ N + +LA GT Y++PE+ + +PY+NK DIWS G VL E+ T K PF ++ + K+ + F PI P S LH I+ V P +RPS
Sbjct: 1 MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGI----ARVLNNSM--ELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVL---KICQAHFAPISPGFSRELHSLISQLFQVSPRDRPS 249
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: AURKC (aurora kinase C [Source:HGNC Symbol;Acc:HGNC:11391]) HSP 1 Score: 111.694 bits (278), Expect = 2.696e-26 Identity = 88/326 (26.99%), Postives = 144/326 (44.17%), Query Frame = 3
Query: 1152 FSNPRTIAE------AKEAIAVANKTSEQDLYVIDGQNHDEPSERDRFSQGIIIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVK---------KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
S+PR + + A E +A AN+T++Q P+ R R + ++ FE + G+G FG V Y R+ + FIV + ++ L R+ I A L N+LR +L + Y P G L K + K +E+ I ++ + H ++IHRDIKP+N++L G K+ DFG S +T L + + GT++Y+ PE+I R Y K+D+W G++ E++ PPF A+ + K+ +F MP+ G I+ L P ER ++ W+
Sbjct: 1 MSSPRAVVQLGKAQPAGEELATANQTAQQP---------SSPAMR-RLT----------VDDFEIGRPLGKGKFGNV--YLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMC--------GTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVD-VRFPLSMPL--GARDLISRLLRYQPLERLPLAQILKHPWV 293
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CAMK1D (calcium/calmodulin dependent protein kinase ID [Source:HGNC Symbol;Acc:HGNC:19341]) HSP 1 Score: 112.464 bits (280), Expect = 3.237e-26 Identity = 75/272 (27.57%), Postives = 132/272 (48.53%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVK-----KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQ-KFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCK 2108
FEF + G GAF V L +E+ +G F VK L + S+ + + K+ N++ ++ + + +L M + GG L I + E+D + Q+L + LH++ I+HRD+KP+N++ DE + DFGLS+ + + + GT Y+APE++ +PYS +D WS G++ ++ PPF+ D ++ ++ K + +F ISD FI + + DP++R + E WI + + K
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGK-------GDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CAMK2G (calcium/calmodulin dependent protein kinase II gamma [Source:HGNC Symbol;Acc:HGNC:1463]) HSP 1 Score: 114.775 bits (286), Expect = 3.862e-26 Identity = 79/275 (28.73%), Postives = 135/275 (49.09%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
R + ++ +E G+GAF V ++ S ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D +QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E ++ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + + + W+
Sbjct: 9 RFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAI-------EVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITADQALKHPWV 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CAMK2A (calcium/calmodulin dependent protein kinase II alpha [Source:HGNC Symbol;Acc:HGNC:1460]) HSP 1 Score: 112.079 bits (279), Expect = 4.970e-26 Identity = 80/289 (27.68%), Postives = 135/289 (46.71%), Query Frame = 3
Query: 1293 IEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY--FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCKC 2111
I R E ++ +E G+GAF V + ++G ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D QIL + H++ ++HRD+KP+N++L +G KL DFGL+ ++ + A+ F GT Y++PE++R PY +D+W+ G++L ++ PPF W D + K + F + P + L IN LT++PS+R + + WI + C
Sbjct: 4 ITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAI--------EVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPF-WDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL---INKMLTINPSKRITAAEALKHPWISHRSTVASC 280
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305]) HSP 1 Score: 112.079 bits (279), Expect = 6.065e-27 Identity = 82/274 (29.93%), Postives = 138/274 (50.36%), Query Frame = 3
Query: 1314 EHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADG-RITIELKK----MQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIID 2090
++++ +E G+GAF V + +G +F K +N K S L R+A I KL N++R + I+ + +L + GG L + I +E D QIL I H I+HRD+KP+N++L +G KL DFGL+ +++D A + F GT Y++PE+++ PYS +DIW+ G++L ++ PPF W D R+ ++K ++ + P + L I+S LTV+P +R + + + WI +
Sbjct: 10 DNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAI--------EVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSL---IDSMLTVNPKKRITADQALKVPWICN 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305]) HSP 1 Score: 112.079 bits (279), Expect = 6.065e-27 Identity = 82/274 (29.93%), Postives = 138/274 (50.36%), Query Frame = 3
Query: 1314 EHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADG-RITIELKK----MQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIID 2090
++++ +E G+GAF V + +G +F K +N K S L R+A I KL N++R + I+ + +L + GG L + I +E D QIL I H I+HRD+KP+N++L +G KL DFGL+ +++D A + F GT Y++PE+++ PYS +DIW+ G++L ++ PPF W D R+ ++K ++ + P + L I+S LTV+P +R + + + WI +
Sbjct: 10 DNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAI--------EVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSL---IDSMLTVNPKKRITADQALKVPWICN 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305]) HSP 1 Score: 112.079 bits (279), Expect = 6.065e-27 Identity = 82/274 (29.93%), Postives = 138/274 (50.36%), Query Frame = 3
Query: 1314 EHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADG-RITIELKK----MQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIID 2090
++++ +E G+GAF V + +G +F K +N K S L R+A I KL N++R + I+ + +L + GG L + I +E D QIL I H I+HRD+KP+N++L +G KL DFGL+ +++D A + F GT Y++PE+++ PYS +DIW+ G++L ++ PPF W D R+ ++K ++ + P + L I+S LTV+P +R + + + WI +
Sbjct: 10 DNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAI--------EVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSL---IDSMLTVNPKKRITADQALKVPWICN 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305]) HSP 1 Score: 112.079 bits (279), Expect = 6.181e-27 Identity = 82/274 (29.93%), Postives = 138/274 (50.36%), Query Frame = 3
Query: 1314 EHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADG-RITIELKK----MQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIID 2090
++++ +E G+GAF V + +G +F K +N K S L R+A I KL N++R + I+ + +L + GG L + I +E D QIL I H I+HRD+KP+N++L +G KL DFGL+ +++D A + F GT Y++PE+++ PYS +DIW+ G++L ++ PPF W D R+ ++K ++ + P + L I+S LTV+P +R + + + WI +
Sbjct: 10 DNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAI--------EVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSL---IDSMLTVNPKKRITADQALKVPWICN 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305]) HSP 1 Score: 112.079 bits (279), Expect = 6.181e-27 Identity = 82/274 (29.93%), Postives = 138/274 (50.36%), Query Frame = 3
Query: 1314 EHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADG-RITIELKK----MQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIID 2090
++++ +E G+GAF V + +G +F K +N K S L R+A I KL N++R + I+ + +L + GG L + I +E D QIL I H I+HRD+KP+N++L +G KL DFGL+ +++D A + F GT Y++PE+++ PYS +DIW+ G++L ++ PPF W D R+ ++K ++ + P + L I+S LTV+P +R + + + WI +
Sbjct: 10 DNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAI--------EVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPF-WDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSL---IDSMLTVNPKKRITADQALKVPWICN 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Nek2 (gene:FBgn0029970 transcript:FBtr0071142) HSP 1 Score: 124.79 bits (312), Expect = 3.450e-29 Identity = 90/281 (32.03%), Postives = 146/281 (51.96%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLN-----DVKC-SLYRDAFIGAKLSQSNLLRYSE--VIKGQHSAHLAMPYMPGGTLSKHIYKGRCQN----EEDIFKISYQILAQI----NKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPI-SDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNL 2096
+ ++ +E L G G+FGT +++ +G F K +N + KC +L + + +L N+++Y V + S ++ M GG L++ + + R Q E I+++ +Q+ + NK+ I+HRDIKP NI LD GN KL DFGL AR+ D S AA F GT +YM+PEL++ R Y K D+W+ G ++ EM +PPF A +++ +K+ + +F I I S L + I L VD +RP E +I ++ N+
Sbjct: 14 KTLQDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFGL----ARMLRRDQS--FAASFVGTPHYMSPELVKGRKYDRKSDVWAVGCLVYEMCALRPPFRGRAFDQLS---EKIAQGEFSRIPAIYSTDLQEIIAFMLAVDHEQRPGIEVIIRHPLVVRNI 285
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0333673) HSP 1 Score: 112.849 bits (281), Expect = 5.475e-26 Identity = 81/275 (29.45%), Postives = 138/275 (50.18%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADG-RITIELKK----MQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
R ++++ +E G+GAF V ++ +G +F K +N K + L R+A I KL N++R + I+ ++ +L + GG L + I +E D QIL +N H+ ++HRD+KP+N++L +G KL DFGL+ E D A + F GT Y++PE+++ PY +DIW+ G++L ++ PPF W D R+ ++K ++ + P + L IN LTV+P++R + + WI
Sbjct: 9 RFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAI-------EVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPF-WDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNL---INQMLTVNPNKRITAAEALKHPWI 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0300377) HSP 1 Score: 112.849 bits (281), Expect = 5.853e-26 Identity = 81/275 (29.45%), Postives = 138/275 (50.18%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADG-RITIELKK----MQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
R ++++ +E G+GAF V ++ +G +F K +N K + L R+A I KL N++R + I+ ++ +L + GG L + I +E D QIL +N H+ ++HRD+KP+N++L +G KL DFGL+ E D A + F GT Y++PE+++ PY +DIW+ G++L ++ PPF W D R+ ++K ++ + P + L IN LTV+P++R + + WI
Sbjct: 9 RFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAI-------EVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPF-WDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNL---INQMLTVNPNKRITAAEALKHPWI 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0089217) HSP 1 Score: 112.849 bits (281), Expect = 5.853e-26 Identity = 81/275 (29.45%), Postives = 138/275 (50.18%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADG-RITIELKK----MQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
R ++++ +E G+GAF V ++ +G +F K +N K + L R+A I KL N++R + I+ ++ +L + GG L + I +E D QIL +N H+ ++HRD+KP+N++L +G KL DFGL+ E D A + F GT Y++PE+++ PY +DIW+ G++L ++ PPF W D R+ ++K ++ + P + L IN LTV+P++R + + WI
Sbjct: 9 RFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAI-------EVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPF-WDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNL---INQMLTVNPNKRITAAEALKHPWI 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0089218) HSP 1 Score: 112.849 bits (281), Expect = 5.853e-26 Identity = 81/275 (29.45%), Postives = 138/275 (50.18%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADG-RITIELKK----MQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
R ++++ +E G+GAF V ++ +G +F K +N K + L R+A I KL N++R + I+ ++ +L + GG L + I +E D QIL +N H+ ++HRD+KP+N++L +G KL DFGL+ E D A + F GT Y++PE+++ PY +DIW+ G++L ++ PPF W D R+ ++K ++ + P + L IN LTV+P++R + + WI
Sbjct: 9 RFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAI-------EVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPF-WDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNL---INQMLTVNPNKRITAAEALKHPWI 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: nek1 (NIMA-related kinase 1 [Source:ZFIN;Acc:ZDB-GENE-040730-1]) HSP 1 Score: 118.627 bits (296), Expect = 3.434e-29 Identity = 81/272 (29.78%), Postives = 135/272 (49.63%), Query Frame = 3
Query: 1311 MEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKL------NDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHI--YKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPI-MPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLH 2099
M+ +E L++ G G+FG L + R G ++++K++ N + ++ + A +S N+++Y E + ++ M Y GG L K I +G EE I QI + +H +I+HRDIK NI L + G +L DFG+ AR+ N + +LA GT Y++PE+ +PY+NK DIW+ G VL EM T K H G + + K+ + + P+ + S L + +P ERPS ++ ++ +H
Sbjct: 1 MDKYERLKKIGEGSFGKAILVKSRTDGRQYVIKEIGISRMSNKERQESRKEVAVLANMSHPNIVQYKESFEESGCLYIVMDYCEGGDLFKKINNQRGSLFPEEQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGI----ARVLNSTV--ELARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYEMCTLK---HAFEAGNMKNLVLKIIRGSYPPVSIHYSPDLRSLLAQLFKRNPRERPSVSTILDKPFLARRIH 263
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: camk1db (calcium/calmodulin-dependent protein kinase 1Db [Source:ZFIN;Acc:ZDB-GENE-070112-1872]) HSP 1 Score: 118.242 bits (295), Expect = 3.206e-28 Identity = 77/272 (28.31%), Postives = 134/272 (49.26%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVK-----KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQ-KFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCK 2108
FEF + G GAF V L QE+ +G+ + VK L + + + + K+ N++ ++ + +L M + GG L I + E+D + Q+L +N LH L I+HRD+KP+N++ E + DFGLS+ E ++ + + GT Y+APE++ +PYS +D WS G++ ++ PPF+ D ++ ++ K + +F ISD FIN+ + DP +R + + + WI + +CK
Sbjct: 24 FEFKEILGTGAFSEVVLAQEKATGDMYAVKCIPKKALRGKESGIENEIAVLRKIKHENIVALEDIYESPSHLYLIMQLVSGGELFDRIVERGFYTEQDASALIKQVLDAVNYLHSLGIVHRDLKPENLLYFNPHEESKIMISDFGLSKM------EGAANDIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFINNLMQKDPEKRFTCDEALRHPWIAGDTALCK 289
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: camk1da (calcium/calmodulin-dependent protein kinase 1Da [Source:ZFIN;Acc:ZDB-GENE-080402-7]) HSP 1 Score: 118.242 bits (295), Expect = 8.611e-28 Identity = 81/274 (29.56%), Postives = 134/274 (48.91%), Query Frame = 3
Query: 1314 EHFEFLQEKGRGAFGTVDLYQERISGNKFIVK-----KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIE-LKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCK 2108
E FEF + G GAF V L +ER +G + VK L + S+ + + K+ N++ ++ + +L M + GG L I + E+D + Q+L +N LH + I+HRD+KP+N++ +G + DFGLS+ E D ++ GT Y+APE++ +PYS +D WS G++ ++ PPF+ D ++ + LK +F ISD FI+ + DPS+R + E + WI + +CK
Sbjct: 23 EIFEFKEVLGTGAFSEVVLAEERSTGKMYAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESSDHLYLIMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVNYLHTMGIVHRDLKPENLLYFNPQDGSKIMISDFGLSKM------EGTGDVMSTAC-GTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKADYEFDAPYWDDISDSAKDFISCLMEKDPSKRNTCEQALRHPWIAGDTALCK 289
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: camk1db (calcium/calmodulin-dependent protein kinase 1Db [Source:ZFIN;Acc:ZDB-GENE-070112-1872]) HSP 1 Score: 116.701 bits (291), Expect = 1.346e-27 Identity = 77/272 (28.31%), Postives = 134/272 (49.26%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVK-----KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQ-KFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCK 2108
FEF + G GAF V L QE+ +G+ + VK L + + + + K+ N++ ++ + +L M + GG L I + E+D + Q+L +N LH L I+HRD+KP+N++ E + DFGLS+ E ++ + + GT Y+APE++ +PYS +D WS G++ ++ PPF+ D ++ ++ K + +F ISD FIN+ + DP +R + + + WI + +CK
Sbjct: 24 FEFKEILGTGAFSEVVLAQEKATGDMYAVKCIPKKALRGKESGIENEIAVLRKIKHENIVALEDIYESPSHLYLIMQLVSGGELFDRIVERGFYTEQDASALIKQVLDAVNYLHSLGIVHRDLKPENLLYFNPHEESKIMISDFGLSKM------EGAANDIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFINNLMQKDPEKRFTCDEALRHPWIAGDTALCK 289
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: camk2g1 (calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1 [Source:ZFIN;Acc:ZDB-GENE-050913-146]) HSP 1 Score: 118.242 bits (295), Expect = 2.365e-27 Identity = 82/282 (29.08%), Postives = 137/282 (48.58%), Query Frame = 3
Query: 1284 GIIIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
I+ R + ++ +E G+GAF V ++ +G ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E D+ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + E + W+
Sbjct: 2 ATIVTSTRFTDEYQLYEELGKGAFSVVRRCVKKSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCISQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAI-------EVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITAEQALKHPWV 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: banf1 (barrier to autointegration factor 1 [Source:Xenbase;Acc:XB-GENE-5745250]) HSP 1 Score: 115.931 bits (289), Expect = 4.831e-27 Identity = 79/252 (31.35%), Postives = 124/252 (49.21%), Query Frame = 3
Query: 1341 GRGAFGTVDLYQERISGNKFIVKKLNDVKC-----SLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHI--YKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPI-MPISDGLHQFINSCLTVDPSERPSGEHLIG 2072
G G+FG L + S +K+++K++ K ++A + A + SN++ + E +G ++ M Y GG L + I KGR E+ I + QI + +H+ ++HRDIK NI L E N KL DFG +AR+ + A + GT Y+ PE+ PY+NK DIWS G VL E+ T K PF + + + K+ + +KP+ + S L IN +P RPS ++
Sbjct: 13 GEGSFGRALLVCHKSSNHKYVMKEIRLPKSFHAMEDSRKEAVLLANMKHSNIVTFQESFEGDGHLYIVMEYCQGGDLLQKIKLQKGRLFTEQTILQWFVQICLAVQYIHEKRVLHRDIKSKNIFLTESCNIKLGDFG----SARILTSPAA--YACTYVGTPYYVPPEIWENMPYNNKSDIWSLGCVLYELCTLKHPFQAGSWKNLIL---KICQGSYKPLPLQYSYELRSLINQMFRKNPRSRPSASTILS 255
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: banf1 (barrier to autointegration factor 1 [Source:Xenbase;Acc:XB-GENE-5745250]) HSP 1 Score: 112.464 bits (280), Expect = 4.945e-27 Identity = 79/251 (31.47%), Postives = 125/251 (49.80%), Query Frame = 3
Query: 1347 GAFGTVDLYQERISGNKFIVKKLNDVKCSLY------RDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHI--YKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPI-MPISDGLHQFINSCLTVDPSERPSGEHLIG 2072
G+FG L + S +K+++K++ K S + ++A + A + SN++ + E +G ++ M Y GG L + I KGR E+ I + QI + +H+ ++HRDIK NI L E N KL DFG +AR+ + A + GT Y+ PE+ PY+NK DIWS G VL E+ T K PF + + + K+ + +KP+ + S L IN +P RPS ++
Sbjct: 10 GSFGRALLVCHKSSNHKYVMKEIRLPK-SFHAMEDSRKEAVLLANMKHSNIVTFQESFEGDGHLYIVMEYCQGGDLLQKIKLQKGRLFTEQTILQWFVQICLAVQYIHEKRVLHRDIKSKNIFLTESCNIKLGDFG----SARILTSPAA--YACTYVGTPYYVPPEIWENMPYNNKSDIWSLGCVLYELCTLKHPFQAGSWKNLIL---KICQGSYKPLPLQYSYELRSLINQMFRKNPRSRPSASTILS 250
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: banf1 (barrier to autointegration factor 1 [Source:Xenbase;Acc:XB-GENE-5745250]) HSP 1 Score: 115.546 bits (288), Expect = 5.252e-27 Identity = 82/263 (31.18%), Postives = 129/263 (49.05%), Query Frame = 3
Query: 1311 MEHFEFLQEKGRGAFGTVDLY-QERISGNKFIVKKLNDVKC-----SLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHI--YKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPI-MPISDGLHQFINSCLTVDPSERPSGEHLIG 2072
ME + ++ G G+FG L E S +K+++K++ K ++A + A + SN++ + E +G ++ M Y GG L + I KGR E+ I + QI + +H+ ++HRDIK NI L E N KL DFG +AR+ + A + GT Y+ PE+ PY+NK DIWS G VL E+ T K PF + + + K+ + +KP+ + S L IN +P RPS ++
Sbjct: 1 MEQYNIVRVIGEGSFGRALLVIGEGSSNHKYVMKEIRLPKSFHAMEDSRKEAVLLANMKHSNIVTFQESFEGDGHLYIVMEYCQGGDLLQKIKLQKGRLFTEQTILQWFVQICLAVQYIHEKRVLHRDIKSKNIFLTESCNIKLGDFG----SARILTSPAA--YACTYVGTPYYVPPEIWENMPYNNKSDIWSLGCVLYELCTLKHPFQAGSWKNLIL---KICQGSYKPLPLQYSYELRSLINQMFRKNPRSRPSASTILS 254
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: banf1 (barrier to autointegration factor 1 [Source:Xenbase;Acc:XB-GENE-5745250]) HSP 1 Score: 115.161 bits (287), Expect = 9.855e-27 Identity = 79/252 (31.35%), Postives = 124/252 (49.21%), Query Frame = 3
Query: 1341 GRGAFGTVDLYQERISGNKFIVKKLNDVKC-----SLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHI--YKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPI-MPISDGLHQFINSCLTVDPSERPSGEHLIG 2072
G G+FG L + S +K+++K++ K ++A + A + SN++ + E +G ++ M Y GG L + I KGR E+ I + QI + +H+ ++HRDIK NI L E N KL DFG +AR+ + A + GT Y+ PE+ PY+NK DIWS G VL E+ T K PF + + + K+ + +KP+ + S L IN +P RPS ++
Sbjct: 11 GEGSFGRALLVCHKSSNHKYVMKEIRLPKSFHAMEDSRKEAVLLANMKHSNIVTFQESFEGDGHLYIVMEYCQGGDLLQKIKLQKGRLFTEQTILQWFVQICLAVQYIHEKRVLHRDIKSKNIFLTESCNIKLGDFG----SARILTSPAA--YACTYVGTPYYVPPEIWENMPYNNKSDIWSLGCVLYELCTLKHPFQAGSWKNLIL---KICQGSYKPLPLQYSYELRSLINQMFRKNPRSRPSASTILS 253
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: banf1 (barrier to autointegration factor 1 [Source:Xenbase;Acc:XB-GENE-5745250]) HSP 1 Score: 114.775 bits (286), Expect = 3.112e-26 Identity = 79/252 (31.35%), Postives = 124/252 (49.21%), Query Frame = 3
Query: 1341 GRGAFGTVDLYQERISGNKFIVKKLNDVKC-----SLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHI--YKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPI-MPISDGLHQFINSCLTVDPSERPSGEHLIG 2072
G G+FG L + S +K+++K++ K ++A + A + SN++ + E +G ++ M Y GG L + I KGR E+ I + QI + +H+ ++HRDIK NI L E N KL DFG +AR+ + A + GT Y+ PE+ PY+NK DIWS G VL E+ T K PF + + + K+ + +KP+ + S L IN +P RPS ++
Sbjct: 23 GEGSFGRALLVCHKSSNHKYVMKEIRLPKSFHAMEDSRKEAVLLANMKHSNIVTFQESFEGDGHLYIVMEYCQGGDLLQKIKLQKGRLFTEQTILQWFVQICLAVQYIHEKRVLHRDIKSKNIFLTESCNIKLGDFG----SARILTSPAA--YACTYVGTPYYVPPEIWENMPYNNKSDIWSLGCVLYELCTLKHPFQAGSWKNLIL---KICQGSYKPLPLQYSYELRSLINQMFRKNPRSRPSASTILS 265
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Aurkc (aurora kinase C [Source:MGI Symbol;Acc:MGI:1321119]) HSP 1 Score: 119.783 bits (299), Expect = 1.633e-29 Identity = 77/267 (28.84%), Postives = 129/267 (48.31%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVK---------KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDN 2093
FE + GRG FG V Y R+ N FIV + ++ L R+ I A L N+LR +L + Y PGG L K + + + +++ I ++ + H+ ++IHRDIKP+N++L G K+ DFG S +T L + + GT++Y+ PE+I +PY+ +D+W G++ E++ KPPF + ++++ FKF +P G I+ L PSER S ++ W+ ++
Sbjct: 16 FEIGRPLGRGKFGRV--YLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTPSLRRKTMC--------GTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVD-FKFPSSVPA--GAQDLISKLLRYHPSERLSLAQVLKHPWVREH 269
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Aurkc (aurora kinase C [Source:MGI Symbol;Acc:MGI:1321119]) HSP 1 Score: 119.783 bits (299), Expect = 1.633e-29 Identity = 77/267 (28.84%), Postives = 129/267 (48.31%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVK---------KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDN 2093
FE + GRG FG V Y R+ N FIV + ++ L R+ I A L N+LR +L + Y PGG L K + + + +++ I ++ + H+ ++IHRDIKP+N++L G K+ DFG S +T L + + GT++Y+ PE+I +PY+ +D+W G++ E++ KPPF + ++++ FKF +P G I+ L PSER S ++ W+ ++
Sbjct: 16 FEIGRPLGRGKFGRV--YLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTPSLRRKTMC--------GTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVD-FKFPSSVPA--GAQDLISKLLRYHPSERLSLAQVLKHPWVREH 269
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Aurkc (aurora kinase C [Source:MGI Symbol;Acc:MGI:1321119]) HSP 1 Score: 119.783 bits (299), Expect = 3.263e-29 Identity = 77/267 (28.84%), Postives = 129/267 (48.31%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVK---------KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDN 2093
FE + GRG FG V Y R+ N FIV + ++ L R+ I A L N+LR +L + Y PGG L K + + + +++ I ++ + H+ ++IHRDIKP+N++L G K+ DFG S +T L + + GT++Y+ PE+I +PY+ +D+W G++ E++ KPPF + ++++ FKF +P G I+ L PSER S ++ W+ ++
Sbjct: 55 FEIGRPLGRGKFGRV--YLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTPSLRRKTMC--------GTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVD-FKFPSSVPA--GAQDLISKLLRYHPSERLSLAQVLKHPWVREH 308
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Camk1d (calcium/calmodulin-dependent protein kinase ID [Source:MGI Symbol;Acc:MGI:2442190]) HSP 1 Score: 112.849 bits (281), Expect = 2.386e-26 Identity = 75/272 (27.57%), Postives = 132/272 (48.53%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVK-----KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQ-KFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCK 2108
FEF + G GAF V L +E+ +G F VK L + S+ + + K+ N++ ++ + + +L M + GG L I + E+D + Q+L + LH++ I+HRD+KP+N++ DE + DFGLS+ + + + GT Y+APE++ +PYS +D WS G++ ++ PPF+ D ++ ++ K + +F ISD FI + + DP++R + E WI + + K
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGK-------GDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALSK 287
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Camk2g (calcium/calmodulin-dependent protein kinase II gamma [Source:MGI Symbol;Acc:MGI:88259]) HSP 1 Score: 114.775 bits (286), Expect = 2.651e-26 Identity = 79/275 (28.73%), Postives = 135/275 (49.09%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
R + ++ +E G+GAF V ++ S ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D +QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E ++ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + + + W+
Sbjct: 9 RFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAI-------EVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITADQALKHPWV 272
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q55BN8|NEK2_DICDI (Probable serine/threonine-protein kinase nek2 OS=Dictyostelium discoideum OX=44689 GN=nek2 PE=1 SV=1) HSP 1 Score: 129.798 bits (325), Expect = 6.706e-31 Identity = 94/274 (34.31%), Postives = 142/274 (51.82%), Query Frame = 3
Query: 1311 MEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKL------NDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHL--AMPYMPGGTLSKHIYKGRCQ----NEEDIFKISYQILAQINKLHKLE---IIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPI-MPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
M+ +E L G+G+FG V + + G + K++ K L + I KL N++RY + I + S+ L M + GG LS+ I K R + +EE I++ QIL+ + ++H + I+HRDIKP N+ LDE N KL DFGL A++ NE L A F GT YM+PE I Y+ + D+WS G ++ EM T PPF ++T K+Q ++ PI S+ L + I+ + VDP RP+ L+G +I
Sbjct: 1 MDQYEILGALGKGSFGVVSKIKRKEDGRVLVWKEICYENMQEKEKQLLVNEVNILQKLKHQNIVRYYDRIIDKPSSRLYIIMEHCSGGDLSQLIKKCRNERTYMDEEVIWRTLLQILSALQEIHNRKDGVILHRDIKPGNLFLDENKNIKLGDFGL----AKILNESL---YAHTFVGTPYYMSPEQIHGLKYNERSDVWSVGCLIYEMATLSPPFEATNQAQLT---SKIQVGRYNPIPSQYSEHLSKVISLMINVDPKSRPNVNELLGYSFI 264
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|O88445|AURKC_MOUSE (Aurora kinase C OS=Mus musculus OX=10090 GN=Aurkc PE=1 SV=2) HSP 1 Score: 119.783 bits (299), Expect = 1.142e-28 Identity = 77/267 (28.84%), Postives = 129/267 (48.31%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVK---------KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDN 2093
FE + GRG FG V Y R+ N FIV + ++ L R+ I A L N+LR +L + Y PGG L K + + + +++ I ++ + H+ ++IHRDIKP+N++L G K+ DFG S +T L + + GT++Y+ PE+I +PY+ +D+W G++ E++ KPPF + ++++ FKF +P G I+ L PSER S ++ W+ ++
Sbjct: 16 FEIGRPLGRGKFGRV--YLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWSVHTPSLRRKTMC--------GTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVD-FKFPSSVPA--GAQDLISKLLRYHPSERLSLAQVLKHPWVREH 269
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6YY75|NEK6_ORYSJ (Serine/threonine-protein kinase Nek6 OS=Oryza sativa subsp. japonica OX=39947 GN=NEK6 PE=1 SV=2) HSP 1 Score: 124.02 bits (310), Expect = 2.398e-28 Identity = 90/279 (32.26%), Postives = 146/279 (52.33%), Query Frame = 3
Query: 1311 MEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKL-----ND-VKCSLYRDAFIGAKLSQSNLLRYSE--VIKGQHSAHLAMPYMPGGTLSKHIYKGRCQ--NEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPI-SDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNL-HMCKC 2111
ME +E +++ GRGA+G+ L + ++++KK+ ND + + Y++ + A LS ++ Y + V +G SA + Y GG +++ I K R +EE + + Q+L ++ LH ++HRD+K NI+L + N +L DFGL A+L EDL A+ GT NYM PE++ PY K DIWS G + E++ +P F AAD + + K+ + P+ PI S L Q + S L +P RP+ L+ ++ L C C
Sbjct: 1 MEQYEVVEQIGRGAYGSAYLVVHKGERKRYVMKKIRLSKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGT-SACIVTSYCEGGDMAERIKKARGVLFSEERVCRWFTQLLLALDYLHCNRVLHRDLKCSNILLTKDNNIRLADFGL----AKLLMEDL----ASTIVGTPNYMCPEILADIPYGYKSDIWSLGCCMFEILAHRPAFK-AAD--MASLINKINRSSISPMPPIYSSSLKQIVKSMLRKNPEHRPTAGELLRHPYLQPYLAESCSC 267
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q10056|SHK2_SCHPO (Serine/threonine-protein kinase shk2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=shk2 PE=3 SV=1) HSP 1 Score: 119.398 bits (298), Expect = 1.104e-26 Identity = 84/266 (31.58%), Postives = 136/266 (51.13%), Query Frame = 3
Query: 1311 MEHFEFLQEKGRGAFGTVDLYQERISGNK------FIVKKLNDVKCSLYRDAFIG--AKLSQS---NLLRY--SEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLI 2069
+E+F + G+GA G+V Y ++ G K + K D++C ++ + + +S N++ Y S +++ +H + M YM G+L+ I K + E I +I + I LH IIHRDIK DN++LD GN K+ DFG + ARL+N ++K GT +MAPE+++ Y K+DIWS G++++EM+ +PP+ R + K K +S L F+NSCLT+D R + L+
Sbjct: 306 VEYFNVKHKLGQGASGSV--YLAKVVGGKQLGIFDSVAIKSIDLQCQTRKELILNEITVMRESIHPNIVTYLDSFLVRERH-LWVVMEYMNAGSLTDIIEKSKL-TEAQIARICLETCKGIQHLHARNIIHRDIKSDNVLLDNSGNIKITDFG---FCARLSNR--TNKRVTMV-GTPYWMAPEVVKQNEYGTKVDIWSLGIMIIEMIENEPPYLREDPIRALYLIAKNGTPTLKKPNLVSKNLKSFLNSCLTIDTIFRATAAELL 561
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7YRC6|AURKB_BOVIN (Aurora kinase B OS=Bos taurus OX=9913 GN=AURKB PE=2 SV=1) HSP 1 Score: 114.775 bits (286), Expect = 2.167e-26 Identity = 78/265 (29.43%), Postives = 126/265 (47.55%), Query Frame = 3
Query: 1311 MEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKL-------NDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
++ FE + G+G FG V L +E+ S +K L V+ L R+ I A L N+LR + +L + Y P G L K + K R +E+ I ++ + H ++IHRDIKP+N++L G K+ DFG S + L + + GT++Y+ PE+I R ++ K+D+W G++ E++ PPF A+ + K+ KF P +P+ G FI L +PSER + W+
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELADALTYCHAKKVIHRDIKPENLLLGLRGELKIADFGWSVHAPSLRRKTMC--------GTLDYLPPEMIEGRTHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVD-LKFPPSVPL--GAQDFIYKLLKHNPSERLPLAQVSAHPWV 327
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0BFM2 (Protein kinase domain-containing protein OS=Paramecium tetraurelia OX=5888 GN=GSPATT00028374001 PE=4 SV=1) HSP 1 Score: 150.984 bits (380), Expect = 3.889e-36 Identity = 92/272 (33.82%), Postives = 142/272 (52.21%), Query Frame = 3
Query: 1290 IIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVK----CS---LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
+++ G + Q G+G+FG V L +E +GN F +K + + C+ L R+ I KL N+++ + + + +L + Y GG+L K I K R +EE+ F YQ I LHK++IIHRDIKP+N++LD GN K+ DFG S D L F GTI YMAPE+I+ + + K+DIW G++L EMV KPPF D + + Q+ K++ +S+ I L +P RPS + ++ +W+
Sbjct: 29 VLKTFEGSDFQSMQQTLGQGSFGWVTLVKEIKTGNLFAMKAMRKEELFKYCTVDNLKREIKIQRKLHHPNIIKLDSYFEDKTNVYLILEYAEGGSLFKKIKKERRLSEEEAFHYLYQTCLGIEYLHKMKIIHRDIKPENLLLDAKGNIKICDFGWSTEM---------DNLKKAFCGTIEYMAPEMIKSQSTNFKLDIWCLGVLLYEMVQGKPPFTGRNDQEKCVAILSGQQLKYEEF--VSEDCKALIAMILQANPFNRPSIQGILNHKWM 289
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0BWA1 (Protein kinase domain-containing protein OS=Paramecium tetraurelia OX=5888 GN=GSPATT00032670001 PE=4 SV=1) HSP 1 Score: 145.976 bits (367), Expect = 1.143e-34 Identity = 96/295 (32.54%), Postives = 153/295 (51.86%), Query Frame = 3
Query: 1332 QEKGRGAFGTVDLYQERISGNKFIVKKLNDVK----CS---LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCKCDDNT*WNNQYNSIQPNINHIRISEYSLS 2195
Q G+G+FG V L +E +G F +K + + C+ L R+ I KL+ +++ + + + +L + Y GG+L K I K R +E++ + YQ I LHK++IIHRDIKP+N++LD GN K+ DFG S D L F GTI YMAPE+I+ + + K+DIW G++L EMV KPPF D + + Q+ K++ +S+ I L +P RPS + ++ +W++ + +N+Q NS +I+ + + EYS S
Sbjct: 3 QTLGQGSFGWVTLVREIQTGKLFAMKAMKKAELFKYCTIDNLKREIKIQRKLNHPHIIDLDSYFEDKTNVYLILEYAEGGSLFKRIKKQRRLSEDEAYHYLYQTCLGIEYLHKMKIIHRDIKPENLLLDAKGNIKICDFGWSTEM---------DNLKKAFCGTIEYMAPEMIKSQSTNYKLDIWCLGVLLYEMVQGKPPFTGKNDQEKCVAILSGQQLKYEE--SVSEDCKSLIAMILQPNPFNRPSIQGILNHKWMLSK------QQSKSYNDQLNS--RSISMLMMEEYSHS 278
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0DG76 (Protein kinase domain-containing protein OS=Paramecium tetraurelia OX=5888 GN=GSPATT00002172001 PE=3 SV=1) HSP 1 Score: 138.272 bits (347), Expect = 7.554e-32 Identity = 82/273 (30.04%), Postives = 146/273 (53.48%), Query Frame = 3
Query: 1275 FSQGIIIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDI--FKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISD-GLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
Q +I++ ++ + L++ G+G+FGTV ++ +I G + +KK+N +CS ++ I L+ N++++ I+ ++ M Y GTL+ QN E+ + I Q+ LH+ IIHRD+KPDNI+LD+ GNPK+ DFGL+ Y + +++ F GT +MAPE+I+ P + K+D+WS +L ++ KP G +++++ FK I++ + +N L DP ER S + ++ ++WI
Sbjct: 52 IEQAVIVDKQSVIKEMQLLEQIGQGSFGTV--HKIQIQGQLYALKKMNKNQCS--KEVRIHKHLNHKNIIQFHYFIEDDDYIYIVMEYASKGTLT--------QNRENCNFYNIFIQLCEATMYLHEKGIIHRDLKPDNILLDKNGNPKICDFGLATYESVISS----------FSGTFEFMAPEVIKNLPQTQKVDVWSLAAILYWLLENKP----LVQGNQIEKMQQILDFKSPQFTKITNPQIQDLLNQMLVPDPDERISLQGVLNNKWI 298
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0BZI1 (Protein kinase domain-containing protein OS=Paramecium tetraurelia OX=5888 GN=GSPATT00033801001 PE=4 SV=1) HSP 1 Score: 137.887 bits (346), Expect = 2.780e-31 Identity = 87/272 (31.99%), Postives = 142/272 (52.21%), Query Frame = 3
Query: 1305 RGMEHFEFLQEK-GRGAFGTVDLYQERISGNKFIVKKLNDVK----CS---LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNL 2096
R + F+ +Q+ G+G+FG V L +E +G +K + + C+ L R+ I KL+ N+++ + + + +L + Y GG+L K I K R +E++ YQ I+ LHK +IIHRDIKP+N++LD GN K+ DFG ++ + N L F GTI YMAPE+I+ + + K+DIW G++L EMV KPPF D + K+ +S+ I+ L +P RPS + ++ +W++ +
Sbjct: 64 RDISDFQAMQQTLGQGSFGWVTLVKEISTGKLLAMKAMKKAELFKYCTVDNLKREIKIQRKLNHPNIIKLDSYFEDKTNVYLVLEYAEGGSLFKQIKKQRHLSEDEASHYLYQTCLGIDYLHKQKIIHRDIKPENLLLDNKGNIKICDFG---WSTEMGN------LKKAFCGTIEYMAPEMIKSQSTNYKLDIWCLGVLLYEMVQGKPPFTGRNDQEKCQAILSGSPLKYDEY--VSEDCKSLISMILQQNPFNRPSIQGILSHRWMLSKI 324
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: B4NCW1 (Protein kinase domain-containing protein OS=Drosophila willistoni OX=7260 GN=Dwil\GK10114 PE=4 SV=1) HSP 1 Score: 139.428 bits (350), Expect = 1.837e-30 Identity = 99/282 (35.11%), Postives = 152/282 (53.90%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLN-----DVKC-SLYRDAFIGAKLSQSNLLRYSE--VIKGQHSAHLAMPYMPGGTLSKHIYKGRCQN----EEDIFKISYQILAQI----NKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIEL-KKMQKFKFKPIMPI-SDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNL 2096
+ ++ +E L G G FGT +++I+G+ F K +N + KC SL + + ++L N+++Y V + S ++ M GG L++ I K R Q E I+++ +Q+ + NK+ I+HRDIKP NI LDE GN KL DFGL+R AR N AA F GT +YM+PEL++ R Y K D+WS G ++ EM +PPF GR+ +L KK+ + +F I + S L + I+ L+VD ERP E +I ++ N+
Sbjct: 24 KTLQDYEVLAVMGNGTFGTCYKVRDKITGHLFAWKGMNYDELDEEKCDSLISEINVLSQLQHPNIVQYYHHLVNREAKSIYIVMECCAGGDLAQVIQKARKQKQRFEESYIWRVLFQLCRALQVCHNKIANGTILHRDIKPANIFLDERGNAKLGDFGLARMLARNQN------FAASFVGTPHYMSPELVKGRQYDRKSDVWSVGCLIYEMCALQPPFR----GRVFEQLTKKITQGEFNGIPKVFSSDLQEIISFMLSVDHEERPGIEVIIRHPLVVRNI 295
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: camk2g1 (calcium/calmodulin-dependent protein kinase type II subunit gamma-like [Source:NCBI gene;Acc:103032713]) HSP 1 Score: 119.783 bits (299), Expect = 5.583e-28 Identity = 82/282 (29.08%), Postives = 138/282 (48.94%), Query Frame = 3
Query: 1284 GIIIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
I+ R + ++ +E G+GAF V ++ +G ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D + QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E D+ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + E + W+
Sbjct: 2 ATIVTSTRFTDEYQLYEELGKGAFSVVRRCVKKSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASQCINQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAI-------EVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITAEQALKHPWV 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: camk2g1 (calcium/calmodulin-dependent protein kinase type II subunit gamma-like [Source:NCBI gene;Acc:103032713]) HSP 1 Score: 119.783 bits (299), Expect = 7.900e-28 Identity = 82/282 (29.08%), Postives = 138/282 (48.94%), Query Frame = 3
Query: 1284 GIIIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
I+ R + ++ +E G+GAF V ++ +G ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D + QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E D+ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + E + W+
Sbjct: 2 ATIVTSTRFTDEYQLYEELGKGAFSVVRRCVKKSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASQCINQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAI-------EVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITAEQALKHPWV 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: camk2g1 (calcium/calmodulin-dependent protein kinase type II subunit gamma-like [Source:NCBI gene;Acc:103032713]) HSP 1 Score: 119.398 bits (298), Expect = 8.811e-28 Identity = 82/282 (29.08%), Postives = 138/282 (48.94%), Query Frame = 3
Query: 1284 GIIIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
I+ R + ++ +E G+GAF V ++ +G ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D + QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E D+ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + E + W+
Sbjct: 2 ATIVTSTRFTDEYQLYEELGKGAFSVVRRCVKKSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASQCINQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAI-------EVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITAEQALKHPWV 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: nek8 (NIMA related kinase 8 [Source:NCBI gene;Acc:103024333]) HSP 1 Score: 120.168 bits (300), Expect = 1.079e-27 Identity = 91/261 (34.87%), Postives = 134/261 (51.34%), Query Frame = 3
Query: 1311 MEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCSLYRDAFIGAK--------LSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQ---NEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGN-PKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMP-ISDGLHQFINSCLTVDPSERP 2051
ME +E ++ GRGAFG V L + R+ G I+K++ + + RD + A+ L+ N++ Y E + +AM Y PGGTL+ +I K RC +E+ I QIL + +H I+HRD+K NI+LD+ K+ DFG+S+ L K AY GT Y++PEL +PY+ K DIW+ G VL E+ + K F A + + K+ F PI S L Q I + L +DPS+RP
Sbjct: 1 MEKYEKIKVVGRGAFGIVHLCRRRVDGALVILKEIPVEQ--MTRDERLAAQNECQVLKLLNHPNIIEYYENFLEDKALMIAMEYAPGGTLADYIQK-RCNSLLDEDTILHFFVQILLALYHVHNKLILHRDLKTQNILLDKHQMIVKIGDFGISKI--------LVSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAA---NLPALVLKIMSGTFAPISDRYSPELRQLILTMLNLDPSKRP 247
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: camk2g1 (calcium/calmodulin-dependent protein kinase type II subunit gamma-like [Source:NCBI gene;Acc:103032713]) HSP 1 Score: 119.398 bits (298), Expect = 1.146e-27 Identity = 82/283 (28.98%), Postives = 138/283 (48.76%), Query Frame = 3
Query: 1284 GIIIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWII 2087
I+ R + ++ +E G+GAF V ++ +G ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D + QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E D+ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + E + W+
Sbjct: 2 ATIVTSTRFTDEYQLYEELGKGAFSVVRRCVKKSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASQCINQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAI-------EVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITAEQALKHPWVC 273
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008748.1 (pep scaffold:Pmarinus_7.0:GL476577:591:63029:-1 gene:ENSPMAG00000007907.1 transcript:ENSPMAT00000008748.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 114.775 bits (286), Expect = 6.568e-28 Identity = 81/281 (28.83%), Postives = 132/281 (46.98%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIM--PISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCKC 2111
R + ++ +E G+GAF V + +G +F K +N K S L R+A I L SN++R E I + +L + GG L + I +E D QIL ++ H+ I+HRD+KP+N++L +G KL DFGL+ E D+ A + F GT Y++PE++R PY +D+W+ G++L ++ PPF W D + K + F ++ IN LT++P++R + + WI + C
Sbjct: 9 RFTDEYQLYEELGKGAFSVVRRCVKVSTGQEFAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLA-------IEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTAEAKNLINQMLTINPAKRITAAEALKHPWICQRSTVASC 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007414.1 (pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1 gene:ENSPMAG00000006689.1 transcript:ENSPMAT00000007414.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 107.457 bits (267), Expect = 1.072e-25 Identity = 75/256 (29.30%), Postives = 128/256 (50.00%), Query Frame = 3
Query: 1311 MEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHI--YKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMP-ISDGLHQFINSCLTVDPSERP 2051
ME + + + G G+FG L + + G+ +++K++N + S ++ + A + N++ Y E + + + ++ M Y GG L K I KG +E+ I Q+ + +H +I+HRDIK NI L + G +L DFG+ AR+ N + +LA GT Y++PE+ +PY++K D+W+ G VL EM T + H G + + K+ + F P+ S L ++ L DP RP
Sbjct: 1 MERYTMVSQIGEGSFGKAMLVKSKADGHLYVIKEINISRMSPKERDEARKEVCVLANMRHPNIVSYKESFEERGNLYIVMDYCEGGDLFKRINAQKGVLFSEDQILDWLVQLCLALKHVHDRKILHRDIKSQNIFLTKAGIVQLGDFGI----ARVLNS--TTELARTCIGTPYYLSPEICENKPYNHKSDMWALGCVLYEMCTLR---HAFEAGNMKNLVLKIIRGSFPPVSAHYSSELRSTLSGLLRRDPRARP 247
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: MARK3 (microtubule affinity regulating kinase 3 [Source:HGNC Symbol;Acc:HGNC:6897]) HSP 1 Score: 100.138 bits (248), Expect = 1.204e-22 Identity = 76/266 (28.57%), Postives = 138/266 (51.88%), Query Frame = 3
Query: 1317 HFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKH-IYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNE-DLSDKLAAYFPGTINYMAPELIRVRPYSN-KIDIWSFGMVLVEMVTRKPPFHWAADGRITIELK-KMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
++ L+ G+G F V L + ++G + VK ++ + + L+R+ I L+ N+++ EVI+ + + +L M Y GG + + + GR + +E K QI++ + H+ I+HRD+K +N++LD N K+ DFG S NE L KL F G+ Y APEL + + Y ++D+WS G++L +V+ PF DG+ EL+ ++ + K++ +S + L + P +R S E ++ +W+
Sbjct: 67 NYRLLKTIGKGNFAKVKLAKHTLTGQEVAVKIIDKTQLNTSSLQKLFREVRIMKVLNHPNIVKLFEVIEMEKTLYLVMEYSSGGEVFDYLVAHGRMKEKEARAKFR-QIVSAVQYCHQKHIVHRDLKAENLLLDADMNIKIADFGFS-------NEFTLGSKLDT-FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF----DGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLHPLKRGSLEQIMKDRWM 319
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004683.1 (pep scaffold:Pmarinus_7.0:GL488517:199:5283:1 gene:ENSPMAG00000004265.1 transcript:ENSPMAT00000004683.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 93.9745 bits (232), Expect = 1.691e-22 Identity = 50/133 (37.59%), Postives = 79/133 (59.40%), Query Frame = 3
Query: 1521 HLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFH 1916
+L + ++ GG L + K EED+ ++ ++ LH L II+RD+KP+NI+LDE G+ L DFGLS+ E + + AY F GT+ YMAPE++ + +++ D WSFG+++ EM+T PF
Sbjct: 9 YLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDESGHIGLTDFGLSK-------ESIDHEKKAYSFCGTVEYMAPEVVNRKGHTHSADWWSFGVLMFEMLTGTLPFQ 134
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: snrka (SNF related kinase a [Source:ZFIN;Acc:ZDB-GENE-040718-84]) HSP 1 Score: 100.138 bits (248), Expect = 3.674e-22 Identity = 85/276 (30.80%), Postives = 130/276 (47.10%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVK-----KLNDVKCS-LYRDAFIGAKLSQ-SNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISY-QILAQINKLHKLEIIHRDIKPDNIV-LDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPY-SNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI--IDNLHMCKC 2111
++ + GRG F V L + +G K VK KL+ + S L++ KL Q N++R EVI Q +L + GG L +I + +E++ K + Q++ I+ H+L ++HRD+KP+N+V ++ G KL DFG S T KLA G++ Y APE++ Y + +DIWS G++L +V PPF A D L + K+ IS I L DP R S + + G W+ +D KC
Sbjct: 16 YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKSKLDPMATSHLFQQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILELADGGDLYDYIMRHEGGLQEELAKTYFAQVVHAISYCHRLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNLFQPGT------KLATSC-GSLAYSAPEILLGDEYDAPAVDIWSLGVILYMLVCGHPPFQEANDSET---LTMIMDCKYTVPAHISRECKDLIARMLQRDPRRRASLQEMEGHPWLCGVDPSPAAKC 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: MKK2 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]) HSP 1 Score: 115.161 bits (287), Expect = 1.745e-27 Identity = 89/277 (32.13%), Postives = 138/277 (49.82%), Query Frame = 3
Query: 1341 GRGAFGTVDLYQERISGNKFIVKKLNDVKC------SLYRDAFIGAKLSQSNLLRYSEVIKGQHSA--HLAMPYMPGGTLS---KHIYK--GRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRIT-----IELKKM-----QKFKFKPIMPI--SDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNL 2096
G GA G+V + + F +K +N + ++R+ +++Y + + S+ ++AM YM G +L K++ K GR +E I KI+ +L ++ LH+ ++IHRDIKP NI+L+E G KL DFG+S + + LA F GT YMAPE I+ +PYS D+WS G+ L+E+ + PF +IT IEL M + K +P + I S FI+ CL D ERPS ++ WI+ +
Sbjct: 221 GEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRI-SERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVS--------GEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFE---SDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWIVGQM 485
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]) HSP 1 Score: 113.62 bits (283), Expect = 2.709e-26 Identity = 78/286 (27.27%), Postives = 135/286 (47.20%), Query Frame = 3
Query: 1260 SERDRFSQGIIIEMMRGMEHFEFLQEKGRGAFGTV----DLYQERISGNKFIV----KKLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYK---GRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
++ DR + I + Q GRG++G V + + +++ K +V ++LND+ + + L+ +N+++Y I+ + ++ + Y G+L + I + G +NE + Q L + LH +IHRDIK NI+L KL DFG+S + + A GT+N+MAPE++ R S DIWS G +VEM+T+ PP+H D I ++ + P S+ L F++ C + +RP+ + L+ WI
Sbjct: 5 ADTDRVNLTPIQRASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEIS----LLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVT--QTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVST---------IVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANI---YYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWI 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: MKK1 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]) HSP 1 Score: 106.301 bits (264), Expect = 1.499e-24 Identity = 86/283 (30.39%), Postives = 133/283 (47.00%), Query Frame = 3
Query: 1314 EHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKC------SLYRDAFIGAKLSQSNLLRYSEVIKGQH--SAHLAMPYMPGGTLSKHIYK------GRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQ----------KFKFKPIMPI--SDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
+ E L G GA G+V + + F +K +N + ++R+ ++RY + S ++AM YM G +L IYK GR +E+ + KI+ +L ++ LH+ ++IHRDIKP NI+L+E G KL DFG+S + + LA F GT YMAPE I+ +PYS D+WS G+ ++E+ K P + ++ + + + K +P I S FI+ CL D ERPS +I WI
Sbjct: 219 DRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDA-IYKNLLERGGRI-SEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVS--------GEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFP---CSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPWI 488
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: YPL150W_mRNA (Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071]) HSP 1 Score: 106.686 bits (265), Expect = 3.416e-24 Identity = 73/247 (29.55%), Postives = 119/247 (48.18%), Query Frame = 3
Query: 1317 HFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSN-KIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPS 2054
+++ L++ G G+FG V L R + K +K + ++ R+ F + + + EVI + +A+ Y PG L H+ R + + ++ QI + H + +HRD+K +NI+LD+ GN KL DFG +R E ++ GT YMAPELI R Y KIDIWS G++L ++T PF + + ++ + ++P D I+ L +P ERPS
Sbjct: 40 NYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKNDPNIVREVFYHRQFDFPYITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGNAKLTDFGFTR-------ECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIP--DDARDLISRLLAKNPGERPS 277
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: RAD53 (DNA damage response protein kinase; required for cell-cycle arrest, regulation of copper genes in response to DNA damage; phosphorylates nuclear pores to counteract gene gating, preventing aberrant transitions at forks approaching transcribed genes; activates downstream kinase Dun1p; differentially senses mtDNA depletion, mitochondrial ROS; relocalizes to cytosol under hypoxia; human homolog CHEK2 implicated in breast cancer can complement yeast null mutant [Source:SGD;Acc:S000006074]) HSP 1 Score: 105.145 bits (261), Expect = 1.026e-23 Identity = 80/276 (28.99%), Postives = 130/276 (47.10%), Query Frame = 3
Query: 1341 GRGAFGTVDLYQERISGNKFIVKKLNDVKC-----SLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNP---KLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIR-----VRP--------YSNKIDIWSFGMVLVEMVTRKPPFHWAAD-------GRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
G+GAF TV ER +G F VK ++ K + R+ + KL+ ++R + S ++ M ++ GG L + E+ +IS QIL I +H + I HRD+KPDNI++++ +P K+ DFGL++ + F GT+ Y+APE+IR V P YS+ +D+WS G ++ ++T PF + GR + ++ F+ IS+ FI+S L VDP+ R + + WI
Sbjct: 205 GQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQ-DDPVLVKITDFGLAKVQG-------NGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFR------ISEEARDFIDSLLQVDPNNRSTAAKALNHPWI 466
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO40703 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6E0]) HSP 1 Score: 115.546 bits (288), Expect = 2.030e-28 Identity = 81/279 (29.03%), Postives = 136/279 (48.75%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL-----DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSC--------LTVDPSERPSGEHLIGSQWIIDNLH 2099
+EF Q GRG+FG V+ + +G ++ +K +N K L R+ I K+ +L+ E+ + +L M G L K + + + E++ + + Q+++ + LH L+I+HRD+K +NI+L +E N K+ DFGLS + SD + GT YMAPE+I YS + D+WS G+++ + T +PPF AD +K+ + K I+ SD + + L VDP+ R + + ++ WI N H
Sbjct: 27 YEFGQVLGRGSFGVVNEAKHIETGTRWAIKAVNKEKAGSSAVKLLEREVMIMKKIYHEHLIHLEEIYETSKRMYLVMELCDAGGLDKMLERKKRFTEKETWTVIKQLVSAVAYLHDLDIVHRDLKLENILLSHPTGNELLNVKITDFGLSIVKGGVG----SDSMMQSVCGTPMYMAPEVIDDLGYSQQCDVWSIGVIMYTLFTGRPPF--MADTE-----EKLYEIIKKGIVDFSDPCWEVCHESAKNLLLGMLKVDPAHRRTAKEVLIHPWITVNTH 294
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7]) HSP 1 Score: 114.39 bits (285), Expect = 2.585e-28 Identity = 86/269 (31.97%), Postives = 130/269 (48.33%), Query Frame = 3
Query: 1341 GRGAFGTVDLYQERISGNKFIVKKL----------NDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMP--ISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCKC 2111
G GAFG V + + +G + VK++ N+VK F+ A +++Y + ++ M Y+PGG++ +HI + NE K S QIL I LH I+HRDIK NI+ D GN KL DFG S+ + ++ + GT +MAPE+I Y K D+WS G +VEM+T KPP+ AD L K+ +P +P +S +F+ S L ++ RPS + L+ ++ N M C
Sbjct: 11 GAGAFGQVYMCHDLDTGRELAVKQIETGQLNSSTKNEVKALEGEIEFMKA-FRNERIVQYYGIETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYGNVKLADFGASKRLQTIRSKTGFRSVH----GTPYWMAPEVINGEGYGRKADVWSVGCTVVEMLTTKPPW---ADFEPMAALFKIATQPTEPELPSDLSVDAVEFVRSTLRMNSKSRPSADELLRFSFVT-NSSMSTC 270
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49822 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG20]) HSP 1 Score: 110.153 bits (274), Expect = 9.518e-27 Identity = 76/267 (28.46%), Postives = 131/267 (49.06%), Query Frame = 3
Query: 1311 MEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCSLY------RDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHI--YKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPI-MPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
ME + +++ G G+FG L ++R G +++K++N + ++ + ++L N++ Y E + + ++ M Y GG L K I +G +E+ + QI + +H +I+HRDIK NI L G K+ DFG++R +LA GT Y++PE++ RPY+NK DIWS G VL EM+T K F + + K+ + + PI + S + + L +P +RPS ++ +I
Sbjct: 1 MERYVRVKKIGEGSFGKALLVKKRNDGKHYVIKEINICRMKPREREESRKEVKVLSQLKHPNIVSYQESFEESGNLYIVMDYCDGGDLYKKINGQRGIAFSEDQVMDWFVQICLGLKHVHDRKILHRDIKSQNIFLTRHGIIKMGDFGIARVLHSTV------ELARTCIGTPYYLSPEIVENRPYNNKSDIWSLGCVLYEMLTLKHAFEAGNMKNLVL---KIIRGSYPPIPLRYSADIRMLVAQLLKRNPHDRPSVNTVLKKNFI 258
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO37413 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFU9]) HSP 1 Score: 108.997 bits (271), Expect = 2.329e-26 Identity = 82/272 (30.15%), Postives = 138/272 (50.74%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVI--KGQHSAHLAMPYMPGGTL----SKHIYKGRCQNEEDIFKISYQILAQINKLHKLE----IIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMP-ISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
+E L+ G G++G + + + K+L+ + S L + + +L +++RY + I + + ++ M + G L KH + R E+ ++K+ YQ++ + + H+ + ++HRD+KP N+ LD N KL DFGL AR+ + D S A F GT YM+PE + R Y+ K DIWS G ++ E+ PPF A +I +E K++ +F PI S L Q INS L V+ RPS + L+ + ++
Sbjct: 9 YEELERIGSGSYGICKKIRRKKDNKVLVWKELDYGQMSETEKQMLVSEVNLLRELKHPHIVRYYDRIIDRTNTTIYIVMEFCENGDLGALIKKHKREKRYTAEDLVWKLLYQLVLAVQECHRRKDGGHVLHRDLKPANVFLDANMNVKLGDFGL----ARVLSHDTS--FAKTFVGTPYYMSPEQVNKRSYNEKSDIWSLGCLMYELCALSPPF--TAMDQIRLE-AKIKVGRFHPIPSHYSSSLSQLINSMLQVNDEMRPSIDELLRNPYL 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO36253 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ85]) HSP 1 Score: 107.842 bits (268), Expect = 8.527e-26 Identity = 72/257 (28.02%), Postives = 125/257 (48.64%), Query Frame = 3
Query: 1341 GRGAFGTVDLYQERISGNKFIVK-----KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVL---DEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQ-KFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
G GAF V L +E+ +G+ F VK +L + S+ + I K+ N++ ++ + +L M + GG L I + E+D + QIL + LH L I+HRD+KP+N++ DE + DFGLS+ A+ + D + GT Y+APE+++ +PY +D WS G++ ++ PPF+ +D + ++ + + +F IS+ FI + +DP R + + WI
Sbjct: 24 GTGAFSEVVLAEEKATGSLFAVKCISKKELKGKEESVENEIAILKKVRHKNIIGLKDIFDNKSHLYLVMDLVQGGELFDRIVEKGNYTEQDASALVQQILEAADYLHSLGIVHRDLKPENLLYYSPDEDSKIMISDFGLSKIEAQGSFMDTA-------CGTPGYVAPEVLKQQPYGKAVDCWSIGVITYILLCGYPPFYDDSDANLFAQIMRAEYEFDSPYWDEISESAKDFIRHLMELDPKLRYTCRQALSHPWI 273
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: camk1da (calcium/calmodulin dependent protein kinase ID [Source:NCBI gene;Acc:101162588]) HSP 1 Score: 117.087 bits (292), Expect = 1.477e-27 Identity = 82/275 (29.82%), Postives = 135/275 (49.09%), Query Frame = 3
Query: 1320 FEFLQEKGRGAFGTVDLYQERISGNKFIVK-----KLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPK------LIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIE-LKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCK 2108
F+F + G GAF V L QE++SG F VK L + S+ + + K+ N++ ++ + +L M + GG L I + E+D + Q+L +N LHKL I+HRD+KP+N++ NP+ + DFGLS+ S + + GT Y+APE++ +PYS +D WS G++ ++ PPF+ D ++ + LK +F ISD FI+ + DP++R + E + WI + +CK
Sbjct: 25 FDFKEVLGTGAFSEVVLAQEKLSGRMFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPDHLYLIMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVNYLHKLGIVHRDLKPENLLY---FNPQDESKIMISDFGLSKMEG-------SGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKADYEFDAPYWDDISDSAKDFISCLMEKDPAKRFTCEQALRHPWIAGDTALCK 289
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000013395.2 (calcium/calmodulin-dependent protein kinase type II subunit gamma [Source:NCBI gene;Acc:101170226]) HSP 1 Score: 117.857 bits (294), Expect = 2.521e-27 Identity = 82/275 (29.82%), Postives = 135/275 (49.09%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
R + ++ +E G+GAF V ++ SG ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E D+ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + E + W+
Sbjct: 9 RFTDEYQLYEELGKGAFSVVRRCVKKSSGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCISQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAI-------EVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITAEQALKHPWV 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000041780.1 (calcium/calmodulin-dependent protein kinase type II subunit gamma [Source:NCBI gene;Acc:101170226]) HSP 1 Score: 118.242 bits (295), Expect = 3.239e-27 Identity = 82/276 (29.71%), Postives = 135/276 (48.91%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWII 2087
R + ++ +E G+GAF V ++ SG ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E D+ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + E + W+
Sbjct: 9 RFTDEYQLYEELGKGAFSVVRRCVKKSSGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCISQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAI-------EVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITAEQALKHPWVC 273
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000043786.1 (calcium/calmodulin-dependent protein kinase type II subunit gamma [Source:NCBI gene;Acc:101170226]) HSP 1 Score: 117.472 bits (293), Expect = 4.836e-27 Identity = 82/275 (29.82%), Postives = 135/275 (49.09%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
R + ++ +E G+GAF V ++ SG ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E D+ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + E + W+
Sbjct: 9 RFTDEYQLYEELGKGAFSVVRRCVKKSSGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCISQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAI-------EVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITAEQALKHPWV 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000028623.1 (calcium/calmodulin-dependent protein kinase type II subunit gamma [Source:NCBI gene;Acc:101170226]) HSP 1 Score: 117.087 bits (292), Expect = 6.778e-27 Identity = 82/275 (29.82%), Postives = 135/275 (49.09%), Query Frame = 3
Query: 1305 RGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCS------LYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLD---EGGNPKLIDFGLSRYTARLTNEDLSDKLAAY-FPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFK-----PIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWI 2084
R + ++ +E G+GAF V ++ SG ++ K +N K S L R+A I L N++R + I + +L + GG L + I +E D QIL +N +H+ +I+HRD+KP+N++L +G KL DFGL+ E D+ A + F GT Y++PE++R PY +DIW+ G++L ++ PPF W D + K + F + P + L IN LT++P++R + E + W+
Sbjct: 9 RFTDEYQLYEELGKGAFSVVRRCVKKSSGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCISQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAI-------EVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPF-WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL---INQMLTINPAKRITAEQALKHPWV 272
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000071997.1 (SMESG000071997.1) HSP 1 Score: 1425.61 bits (3689), Expect = 0.000e+0 Identity = 689/695 (99.14%), Postives = 692/695 (99.57%), Query Frame = 3
Query: 39 MKIFVVNGENGGEKTAIEIEGLTFVSEIKLRLSEECRVNYFWLINSNNFLLNDNDHLSRYNLSDNDEIWHGSLENFIKKDDVIVEIFLSGWTPFISWLVVKVNQSMSEIRAALVRIEPDIINIFNGDGQLMEDNQLVTDIDRDGYYRLIISCGRGTNMNLSFDECYKFYKLHILRFKYSKSHLLYYAQFYSEGIQEQTRYQLIYQMIRIREIMSSNDVIDTRLNKNLSDFLFFIKSKLLFQQDISARLLEICYSYWFLIKYFYTSEVWAVVGLYFRLSLLNVLSECSNSVVNLGVSADKSFGGIIIDALDNFVLFLSEFGEILKSSAKLWTDLFSLITLAGSEFDDQFDDSYSKESSCTVKSGGRNHQLVIFSNPRTIAEAKEAIAVANKTSEQDLYVIDGQNHDEPSERDRFSQGIIIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCKCDDNT 2123
MKIFVVNGENGGEKTAIEIEGLTFVSEIKLRL EECRVNYFWLINSNNFLLNDNDHLSRYNLSDNDEIWHGSLENFIKKDDVIVEIFLSGWTPFISWLVVKVNQSMSEIRAALVRIEPDIINIFNGDGQLMEDNQLVTDIDRDGYYRLIISCGRG NMNL+FDECYKFYKLHILRFKYSKSHLLYYAQFYSEGIQEQTRYQLIYQMIRIREIMSSNDVIDTRLNKNLSDFLFFIKSKLLFQQDISARLLEICYSYWFLIKYFYTSEVWAVVGLYFRLSLLNVLSECSNSVVNLGVSADKSFGGIIIDALDNFVLFLSEFGEILKSSAKLWTDLFSLITLAGSEFDDQFDDSYSKESSCTVKSGGRNHQLVIFSNPRTIAEAKEAIAVANKTSEQDLYVIDGQNHDEPSERDRFSQGIIIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFI+KKLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKG CQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPIS+GLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCKCDDNT
Sbjct: 1 MKIFVVNGENGGEKTAIEIEGLTFVSEIKLRLPEECRVNYFWLINSNNFLLNDNDHLSRYNLSDNDEIWHGSLENFIKKDDVIVEIFLSGWTPFISWLVVKVNQSMSEIRAALVRIEPDIINIFNGDGQLMEDNQLVTDIDRDGYYRLIISCGRGANMNLAFDECYKFYKLHILRFKYSKSHLLYYAQFYSEGIQEQTRYQLIYQMIRIREIMSSNDVIDTRLNKNLSDFLFFIKSKLLFQQDISARLLEICYSYWFLIKYFYTSEVWAVVGLYFRLSLLNVLSECSNSVVNLGVSADKSFGGIIIDALDNFVLFLSEFGEILKSSAKLWTDLFSLITLAGSEFDDQFDDSYSKESSCTVKSGGRNHQLVIFSNPRTIAEAKEAIAVANKTSEQDLYVIDGQNHDEPSERDRFSQGIIIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIIKKLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGECQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISEGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCKCDDNT 695
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000024565.1 (SMESG000024565.1) HSP 1 Score: 510.375 bits (1313), Expect = 2.203e-171 Identity = 300/715 (41.96%), Postives = 435/715 (60.84%), Query Frame = 3
Query: 39 MKIFVVNGENGGEKTAIEIEGLTFVSEIKLRLSE--ECRVNY---FWLINSNNFLLNDNDHLSRYNLSDNDEIWHGSLENFIKKDDVIVEIFLSGWTPFISWLVVKVNQSMSEIRAALVRIEPDIINIFNGDGQLMEDNQLVTDIDRDGYYRLIISCGRGTNMNLSFDECYKFYKLHILRFKYSKSHLLYYAQFYSEGIQEQTRYQLIYQMIRIREIMSSNDVIDTRLNKNLSDFL-FFIKSKLLFQQDISARLLEICYSYWFLIKYFYTSEVWAVVGLYFRLSLLNVLSECSNSVVNLGVSADKSFGGIIIDALDNFVLFLSEF-----------------GEILKSSAKLWTDLFSLITLAGSEFDDQFDDSYSKESSCTVKSGGRNHQLVIFSNPRTIAEAKEAIAVANKTSEQDLYVIDGQNHDEPSERDRFSQGII-IEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCSLYRDAFIGAKLSQSN-LLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCK 2108
MKIFV+ EN K I++E + V I+ +L + RV + F + N +++D + Y L + DEI +EN++ DDVI+E+FLSG+ P + +L+V+ N S+S+I++ + RI+ +IINI + G M +Q VT+ YYRLI+ GR +F++C K Y H R + +L Y E + E ++I QM I+ IM SND + RL +NLS+F FIK +F DIS+R+ +IC YW L + ++ W V+GL+FR++LL VL + N A K+F I++DAL V L + GE+++ W D F + SEFD+ F+ Y+K + ++K G + + S+P+TI EAKEA+A DLY I +N D+P++ + + + I+ +M ME+F+FL+E GAFG V + Q++IS + ++KK +++ SL+RD FIG +L S+ L +YS ++K S LAMPY+ GG+L+ I + +C +E + KISYQIL QI++LH+L+I+HRDIKPDNI+LD GN KLIDFGLS+ +T E L +KL AY PGT+NYMAPE++R PYS KIDIWSFGMVLVEMVT PPFH A R+ IELKKM +++FKP + IS +QFI CLTVDP+ERPS + LI SQ+IID L++ K
Sbjct: 1 MKIFVIRVENPEIKIEIKLEEYSLVRNIRNKLDKIFPGRVKWNKHFIKLVHKNIIMDDEKSIGWYKLCEGDEILCVRIENYLCSDDVILEVFLSGFVPEVIYLIVQRNYSISKIKSMIERIQCEIINICDFTGNKMTGSQTVTETSSCAYYRLIVKYGRKETCISTFEDCLKQY--HKFRIIHYYDFILRLRHLY-ECLFETRINEVIKQMNEIKAIMLSNDPFEIRLKENLSEFPSAFIKCHSIFCDDISSRIWDICDDYWQLSRNVIENDEWIVIGLFFRMALLIVLHQYLEHERNHCEIATKTFNSIVVDALGYSVTLLIKIRQMESFCETAGYSFDLIGELMEDICVKWMDPFLSTSRYYSEFDEVFNRYYNK-TFASLKFGNGSVEFHFHSDPQTIIEAKEAMAQKCGVKVNDLYAIYQRNEDKPTDGEPYDETILDFVLMINMENFDFLKEFATGAFGKVFICQDKISSQELVLKKSTEMEFSLHRDIFIGYRLKNSSKLFQYSRIVKDMDSIQLAMPYLSGGSLTSKIQQQKCIHENEKIKISYQILTQIHELHRLQIVHRDIKPDNIILDGAGNAKLIDFGLSKSMENVTIEILLEKLKAYAPGTVNYMAPEILREIPYSYKIDIWSFGMVLVEMVTGNPPFHKKAPPRVVIELKKMVEYEFKPNLLISIEFNQFIKWCLTVDPNERPSAQQLIESQFIIDYLNINK 711
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000024532.1 (SMESG000024532.1) HSP 1 Score: 498.434 bits (1282), Expect = 3.800e-167 Identity = 302/707 (42.72%), Postives = 426/707 (60.25%), Query Frame = 3
Query: 39 MKIFVVNGENGGEKTAIEIEGLTFVSEIKLRL-----------SEECRVNYFWLINSNNFLLNDNDHLSRYNLSDNDEIWHGSLENFIKKDDVIVEIFLSGWTPFISWLVVKVNQSMSEIRAALVRIEPDIINIFNGDGQLMEDNQLVTDIDRDGYYRLIISCGRGTNMNLSFDECYKFYKLHILRFKYSKSHLLYYAQFYSEGIQEQTRYQLIYQMIRIREIMSSNDVIDTRLNKNLSDFLF-FIKSKLLFQQDISARLLEICYSYWFLIK---YFYTSEVWAVVGLYFRLSLLNVLSECSNSVVNLGVSADKSFGGIIIDALDNFVLFLSEFGEILKSSAKLWTDLFSLITLAGSEFDDQFDDSYSKESSCTVKSGGRNHQ---LVIFSNPRTIAEAKEAIAVANKTSEQDLYVIDGQNHDEPSERDRFSQGI-IIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCSLYRDAFIGAK-LSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLH 2099
MKI VVNGEN K IEI+ ++V +IK ++ E R Y N +L+D +++ RY + ++DEIW G +EN+++ DDVI+E+FL+G +P + WL+VK+N S++ IR+ + ++ +INI++ +G+ M++ Q+V+DID GYYRLI+S LSF++C + + RF + ++F E + E LI +IR IMS NDVID RL +NLS+ + SKLLF +I R+L+IC +W K Y+ + F LS+L L + S+S + DKSF GI+IDALD V L + + LK KL+ D F L+ SE+ + + YS + + +++ L + T+ +AK IA S +DLY I+ NHD+ E + +G + E+++ ME+ +E G G FG V YQ+ ISG + +K N K SLYRD FI A ++ S L +YS + K + ++AMPYM GG+L+ +I + E++ +ISYQIL QI KLH+L+IIHRDIKPDNIV D GN KLIDFGLS++ T+E++ +KL AY PGTINYMAPE++R PYS KIDIWSFGMVLVEMVT PPFH A R IELKKM ++KFKP + IS LHQFI SCL V+P+ERPS + LIGSQ+II L
Sbjct: 1 MKISVVNGENLSVKFVIEIDKHSYVGDIKHKIDKILNGQGKWEKEHLRFIY------KNIILHD-EYIKRYKVCESDEIWFGKIENYLRSDDVIIEVFLAGCSPVLIWLIVKINHSITVIRSMIEIVQSKLINIYDWNGREMQNVQIVSDIDPIGYYRLIVSYEDERGKWLSFEDCVRQHDEFTFRFCLN-------SEFEFEDMTEINTVNLIN---KIRTIMSLNDVIDARLKENLSNIPSGVVNSKLLFYYNIQLRILDICQEFWKSTKDSPYYINYNIIKS----FELSILVALHQYSHSRQKDPENKDKSFNGIVIDALDYLVKHLHDHCKDLKYHQKLFFDHFLLVPRPVSEYI-ELRNEYSSQLITKIIINKKDNIAPFLTLLLTQGTVLDAKCEIAQKLGVSIKDLYCINHWNHDKAEEDKIYKEGFYMFEIIKSMENMNLGKEFGAGGFGRVFFYQDIISGKQLAMKTANSDKSSLYRDIFISALIMNNSELFKYSGLFKYKSELYIAMPYMTGGSLTSYIQGKKGLFEKEALRISYQILIQIEKLHELKIIHRDIKPDNIVFDGAGNAKLIDFGLSKWMKNSTDENILEKLKAYAPGTINYMAPEILREIPYSYKIDIWSFGMVLVEMVTGNPPFHKKAPARAIIELKKMVEYKFKPSVLISIELHQFIKSCLIVNPNERPSAQQLIGSQFIIGYLQ 685
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000024843.1 (SMESG000024843.1) HSP 1 Score: 436.417 bits (1121), Expect = 1.657e-144 Identity = 250/577 (43.33%), Postives = 361/577 (62.56%), Query Frame = 3
Query: 405 IFNGDGQLMEDNQLVTDIDRDGYYRLIISCGRGTNMNLSFDECYKFY-KLHILRFKYSKSHLLYYAQFYSEGIQEQTRYQLIYQMIRIREIMSSNDVIDTRLNKNLSDFL-FFIKSKLLFQQDISARLLEICYSYWFLIK------YFYTSEVWAVVGLYFRLSLLNVLSECSNSVVNLGVSADKSFGGIIIDALDNFVLFLSEFGEILKSSAKLWTDLFSLITLAGSEFDDQFDDSYSKESSCTVKSGGRNHQLVIFSNPRTIAEAKEAIAVANKTSEQDLYVIDGQNHDEPSERDRFSQGI-IIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCK 2108
+++ G M++NQ VTDID GYYRLI++CG+ + NL+FDEC + + I+ + YS++ + +F E E R ++I Q+ +IR+I+SSND ID RLN+NLS F F+K LF DI+ R+ +IC Y L+K F ++ W + L+F +LL + + S++V N + KSF I++DALD V L E K +AK W + F LIT + + D+ F S V+ +++ + NP+TI EA +A+A + QDLY I+ D+P++ D + Q + E+M M FE L E G FG V + +++ISG + ++KKL DVK SL+R+ IG+ L L++YSEVI+ + + HL MPY+PGGTL+ +I + +C E ++ +IS+QIL QI++LHK +IIH DIKP+NIV D N KLIDFGL++Y ++DLS K A PGTINYMAPEL + P S KIDIWSFGMV+VEMVT + PF+ G+I + L K+ K++FKP+M IS+ L QFI+ CLTVDP+ RP+ + LI SQ I + L M K
Sbjct: 1 MWDCKGNEMQNNQSVTDIDAFGYYRLIVNCGQEADDNLTFDECCNQHDRCKIILYYYSEN----WWEF--EKFSEIARVKIINQIKKIRQIISSNDTIDPRLNENLSHFPKAFVKQNYLFGHDITKRIWDICNEYRKLMKSYPFSVQFCLNDEWHAMKLFFLTALLVTMRKYSDAVQNDPKNTKKSFNDILVDALDCLVRHLMNPCEDWKHAAKRWLNSFFLITQSDGDMDELF--VKFDPSMIIVRIKSEEYEMDVELNPKTILEATKAVANKFRIDRQDLYSINHWIPDKPNDGDPYFQPMTFFELMSKMADFENLNELANGGFGKVFICEDKISGKQVVMKKLIDVKDSLHREILIGSILFDKELIKYSEVIRDEKNIHLTMPYLPGGTLTSNIQQLKCLGENEVIRISHQILTQISELHKSKIIHCDIKPENIVFDNERNVKLIDFGLAKYIGDFRSKDLSRKRKASSPGTINYMAPELTKEDPNSVKIDIWSFGMVMVEMVTGQLPFNVMGPGQILLRLGKLLKYEFKPMMEISNDLKQFISWCLTVDPNVRPTAQQLIESQLINNYLQMTK 569
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000024843.1 (SMESG000024843.1) HSP 1 Score: 434.491 bits (1116), Expect = 5.738e-144 Identity = 249/569 (43.76%), Postives = 357/569 (62.74%), Query Frame = 3
Query: 429 MEDNQLVTDIDRDGYYRLIISCGRGTNMNLSFDECYKFY-KLHILRFKYSKSHLLYYAQFYSEGIQEQTRYQLIYQMIRIREIMSSNDVIDTRLNKNLSDFL-FFIKSKLLFQQDISARLLEICYSYWFLIK------YFYTSEVWAVVGLYFRLSLLNVLSECSNSVVNLGVSADKSFGGIIIDALDNFVLFLSEFGEILKSSAKLWTDLFSLITLAGSEFDDQFDDSYSKESSCTVKSGGRNHQLVIFSNPRTIAEAKEAIAVANKTSEQDLYVIDGQNHDEPSERDRFSQGI-IIEMMRGMEHFEFLQEKGRGAFGTVDLYQERISGNKFIVKKLNDVKCSLYRDAFIGAKLSQSNLLRYSEVIKGQHSAHLAMPYMPGGTLSKHIYKGRCQNEEDIFKISYQILAQINKLHKLEIIHRDIKPDNIVLDEGGNPKLIDFGLSRYTARLTNEDLSDKLAAYFPGTINYMAPELIRVRPYSNKIDIWSFGMVLVEMVTRKPPFHWAADGRITIELKKMQKFKFKPIMPISDGLHQFINSCLTVDPSERPSGEHLIGSQWIIDNLHMCK 2108
M++NQ VTDID GYYRLI++CG+ + NL+FDEC + + I+ + YS++ + +F E E R ++I Q+ +IR+I+SSND ID RLN+NLS F F+K LF DI+ R+ +IC Y L+K F ++ W + L+F +LL + + S++V N + KSF I++DALD V L E K +AK W + F LIT + + D+ F S V+ +++ + NP+TI EA +A+A + QDLY I+ D+P++ D + Q + E+M M FE L E G FG V + +++ISG + ++KKL DVK SL+R+ IG+ L L++YSEVI+ + + HL MPY+PGGTL+ +I + +C E ++ +IS+QIL QI++LHK +IIH DIKP+NIV D N KLIDFGL++Y ++DLS K A PGTINYMAPEL + P S KIDIWSFGMV+VEMVT + PF+ G+I + L K+ K++FKP+M IS+ L QFI+ CLTVDP+ RP+ + LI SQ I + L M K
Sbjct: 1 MQNNQSVTDIDAFGYYRLIVNCGQEADDNLTFDECCNQHDRCKIILYYYSEN----WWEF--EKFSEIARVKIINQIKKIRQIISSNDTIDPRLNENLSHFPKAFVKQNYLFGHDITKRIWDICNEYRKLMKSYPFSVQFCLNDEWHAMKLFFLTALLVTMRKYSDAVQNDPKNTKKSFNDILVDALDCLVRHLMNPCEDWKHAAKRWLNSFFLITQSDGDMDELF--VKFDPSMIIVRIKSEEYEMDVELNPKTILEATKAVANKFRIDRQDLYSINHWIPDKPNDGDPYFQPMTFFELMSKMADFENLNELANGGFGKVFICEDKISGKQVVMKKLIDVKDSLHREILIGSILFDKELIKYSEVIRDEKNIHLTMPYLPGGTLTSNIQQLKCLGENEVIRISHQILTQISELHKSKIIHCDIKPENIVFDNERNVKLIDFGLAKYIGDFRSKDLSRKRKASSPGTINYMAPELTKEDPNSVKIDIWSFGMVMVEMVTGQLPFNVMGPGQILLRLGKLLKYEFKPMMEISNDLKQFISWCLTVDPNVRPTAQQLIESQLINNYLQMTK 561 The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024411 ID=SMED30024411|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2284bpback to top protein sequence of SMED30024411-orf-1 >SMED30024411-orf-1 ID=SMED30024411-orf-1|Name=SMED30024411-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=696bp MKIFVVNGENGGEKTAIEIEGLTFVSEIKLRLSEECRVNYFWLINSNNFLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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