Protein kinase domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024349 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: AURKC (aurora kinase C [Source:HGNC Symbol;Acc:HGNC:11391]) HSP 1 Score: 135.576 bits (340), Expect = 2.071e-35 Identity = 79/260 (30.38%), Postives = 137/260 (52.69%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFK-PLE--LSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
+DF GR +G+G FG V L +L +S +K + + +E+ + R I++ L H I+ Y A++ Y+++EY P+G L ++K+ + ++ + +++ + + + H ++IHRDI P N+LL +K+ DFG+S V + + KT CGT++YL PE+I + Y D+W +G + +L+G F S E IL K+D + PL L +R ++ +L Y+P R A +LKH
Sbjct: 7 DDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS--VHTPSLRR--KTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRIL---KVDVRFPLSMPLGAR---DLISRLLRYQPLERLPLAQILKH 256
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: AURKC (aurora kinase C [Source:HGNC Symbol;Acc:HGNC:11391]) HSP 1 Score: 135.576 bits (340), Expect = 3.094e-35 Identity = 79/260 (30.38%), Postives = 137/260 (52.69%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFK-PLE--LSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
+DF GR +G+G FG V L +L +S +K + + +E+ + R I++ L H I+ Y A++ Y+++EY P+G L ++K+ + ++ + +++ + + + H ++IHRDI P N+LL +K+ DFG+S V + + KT CGT++YL PE+I + Y D+W +G + +L+G F S E IL K+D + PL L +R ++ +L Y+P R A +LKH
Sbjct: 22 DDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS--VHTPSLRR--KTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRIL---KVDVRFPLSMPLGAR---DLISRLLRYQPLERLPLAQILKH 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: AURKC (aurora kinase C [Source:HGNC Symbol;Acc:HGNC:11391]) HSP 1 Score: 134.806 bits (338), Expect = 3.799e-35 Identity = 78/260 (30.00%), Postives = 134/260 (51.54%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFK-PLE--LSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
+DF GR +G+G FG V L +L +S +K + + +E+ + R I++ L H I+ Y A++ Y+++EY P+G L ++K+ + ++ + +++ + + + H ++IHRDI P N+LL +K+ DFG+S KT CGT++YL PE+I + Y D+W +G + +L+G F S E IL K+D + PL L +R ++ +L Y+P R A +LKH
Sbjct: 7 DDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS-----VHPLPERKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRIL---KVDVRFPLSMPLGAR---DLISRLLRYQPLERLPLAQILKH 255
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: AURKC (aurora kinase C [Source:HGNC Symbol;Acc:HGNC:11391]) HSP 1 Score: 135.576 bits (340), Expect = 5.050e-35 Identity = 79/260 (30.38%), Postives = 137/260 (52.69%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFK-PLE--LSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
+DF GR +G+G FG V L +L +S +K + + +E+ + R I++ L H I+ Y A++ Y+++EY P+G L ++K+ + ++ + +++ + + + H ++IHRDI P N+LL +K+ DFG+S V + + KT CGT++YL PE+I + Y D+W +G + +L+G F S E IL K+D + PL L +R ++ +L Y+P R A +LKH
Sbjct: 41 DDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS--VHTPSLRR--KTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRIL---KVDVRFPLSMPLGAR---DLISRLLRYQPLERLPLAQILKH 290
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: AURKC (aurora kinase C [Source:HGNC Symbol;Acc:HGNC:11391]) HSP 1 Score: 135.191 bits (339), Expect = 5.160e-35 Identity = 79/260 (30.38%), Postives = 137/260 (52.69%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFK-PLE--LSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
+DF GR +G+G FG V L +L +S +K + + +E+ + R I++ L H I+ Y A++ Y+++EY P+G L ++K+ + ++ + +++ + + + H ++IHRDI P N+LL +K+ DFG+S V + + KT CGT++YL PE+I + Y D+W +G + +L+G F S E IL K+D + PL L +R ++ +L Y+P R A +LKH
Sbjct: 38 DDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS--VHTPSLRR--KTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRIL---KVDVRFPLSMPLGAR---DLISRLLRYQPLERLPLAQILKH 287
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: air-1 (Aurora/Ipl1 Related kinase; Aurora/Ipl1-related protein kinase 1 [Source:UniProtKB/TrEMBL;Acc:G5EDL3]) HSP 1 Score: 130.568 bits (327), Expect = 1.450e-33 Identity = 76/265 (28.68%), Postives = 142/265 (53.58%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQII--NVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFLEL 1612
+DF GR +G+G FG V + + K+ +K + + + + R I++ L H I++ YG K+ +++++Y +G L N ++ ++I +Q+ + + H +IHRDI P N+LLD+ N+KL DFG+S VV D + ++ T CGT++YLAPE++S+Q + F DIW++G +F ML+G F ++ +++ I K KI + P + + ++++ ++ +P R ++ H E+
Sbjct: 42 DDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWS-VVADHSKRH---TLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARI-KECKI-YIP-SVVTDGAASLINAIIKKEPQERLPLVDIMAHPWIKEM 299
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: air-1 (Aurora/Ipl1 Related kinase; Aurora/Ipl1-related protein kinase 1 [Source:UniProtKB/TrEMBL;Acc:G5EDL3]) HSP 1 Score: 130.568 bits (327), Expect = 1.450e-33 Identity = 76/265 (28.68%), Postives = 142/265 (53.58%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQII--NVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFLEL 1612
+DF GR +G+G FG V + + K+ +K + + + + R I++ L H I++ YG K+ +++++Y +G L N ++ ++I +Q+ + + H +IHRDI P N+LLD+ N+KL DFG+S VV D + ++ T CGT++YLAPE++S+Q + F DIW++G +F ML+G F ++ +++ I K KI + P + + ++++ ++ +P R ++ H E+
Sbjct: 42 DDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWS-VVADHSKRH---TLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARI-KECKI-YIP-SVVTDGAASLINAIIKKEPQERLPLVDIMAHPWIKEM 299
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 129.028 bits (323), Expect = 2.420e-31 Identity = 83/262 (31.68%), Postives = 137/262 (52.29%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEM----LNYKPSNRPTAASLLKHELF 1603
F K IGRGSFG+V YK + + VV I+ + + +I + I +L+ + + Y+G K K +I+MEY+ GS L+ + K+ + I + ++I++G+E+LH + IHRDI +N+L+ + ++K+ DFG + + +T + TF G+ ++APE+I Y + ADIWS+G T + G + ++ I KN P L + S KE LN P NRP+A++LLKH+
Sbjct: 34 FTKQERIGRGSFGEV--YKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALD-LTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRI--TFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKN-----PPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFI 285
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 129.028 bits (323), Expect = 2.738e-31 Identity = 83/262 (31.68%), Postives = 137/262 (52.29%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEM----LNYKPSNRPTAASLLKHELF 1603
F K IGRGSFG+V YK + + VV I+ + + +I + I +L+ + + Y+G K K +I+MEY+ GS L+ + K+ + I + ++I++G+E+LH + IHRDI +N+L+ + ++K+ DFG + + +T + TF G+ ++APE+I Y + ADIWS+G T + G + ++ I KN P L + S KE LN P NRP+A++LLKH+
Sbjct: 19 FTKQERIGRGSFGEV--YKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALD-LTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRI--TFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKN-----PPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFI 270
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 128.642 bits (322), Expect = 3.011e-31 Identity = 83/262 (31.68%), Postives = 137/262 (52.29%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEM----LNYKPSNRPTAASLLKHELF 1603
F K IGRGSFG+V YK + + VV I+ + + +I + I +L+ + + Y+G K K +I+MEY+ GS L+ + K+ + I + ++I++G+E+LH + IHRDI +N+L+ + ++K+ DFG + + +T + TF G+ ++APE+I Y + ADIWS+G T + G + ++ I KN P L + S KE LN P NRP+A++LLKH+
Sbjct: 14 FTKQERIGRGSFGEV--YKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALD-LTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRI--TFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKN-----PPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFI 265
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: GckIII (gene:FBgn0266465 transcript:FBtr0083399) HSP 1 Score: 129.028 bits (323), Expect = 3.114e-31 Identity = 83/258 (32.17%), Postives = 137/258 (53.10%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELS---SRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
F K IG+GSFG+V +K + + + VV I+ +++ ++I + I +L+ + YYG K K +I+MEY+ GS L+ + K S I + +++++G+++LH + +HRDI +N+LL ++KL DFG + + +T ++ TF GT ++APE+I QY ADIWS+G T + G E ++ I KN P +L+ ++ V+ LN P NRPTA LLK+
Sbjct: 13 FTKQERIGKGSFGEV--FKGIDNRTQQVVAIKIIDLEEAEDEIDDIQQEIMVLSQCDSPYVTKYYGSFLKGTKLWIIMEYLGGGSALDLM-KAGSFEEMHIGIILREVLKGLDYLHSERKLHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKR--NTFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKN-----NPPQLTGSYTKSFKDFVEACLNKDPENRPTAKELLKY 260
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: aurA (gene:FBgn0000147 transcript:FBtr0082483) HSP 1 Score: 124.79 bits (312), Expect = 1.014e-30 Identity = 77/250 (30.80%), Postives = 129/250 (51.60%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIE-KTMSIL-RKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNR 1567
N+F GR +GRG FG V L + +S +K + +E+ + R I++ L H I+ Y + Y+++EY PQG+L N ++ + M +Q + + + +LH IIHRDI P N+LL +K+ DFG+S V + + T CGT++YL PE++ + ++ D+WS+G F +L+G F+ K+ E IL K+D+K E S+ S ++ ++L P +R
Sbjct: 152 NNFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYLILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGHKGVLKIADFGWS--VHEPNSMRM--TLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKIL---KVDYKLPEHISKAASHLISKLLVLNPQHR 394
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: AMPKalpha (gene:FBgn0023169 transcript:FBtr0070216) HSP 1 Score: 125.176 bits (313), Expect = 4.326e-30 Identity = 82/256 (32.03%), Postives = 128/256 (50.00%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYID---LLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFP-ADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELF 1603
G +G G+FGKV + + + + VK + S + I R I L H I+ Y V+ +++MEY+ G L + I K + Q +QII GV++ H + I+HRD+ P N+LLD N ++K+ DFG S ++ D +T CG+ NY APE+IS + Y+ P DIWS G ++ +L G F ++ + T K K F E ++++ +V +ML P R + KHE F
Sbjct: 31 GATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDG---EFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDE---HVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWF 280
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: AMPKalpha (gene:FBgn0023169 transcript:FBtr0070217) HSP 1 Score: 125.176 bits (313), Expect = 4.326e-30 Identity = 82/256 (32.03%), Postives = 128/256 (50.00%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYID---LLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFP-ADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELF 1603
G +G G+FGKV + + + + VK + S + I R I L H I+ Y V+ +++MEY+ G L + I K + Q +QII GV++ H + I+HRD+ P N+LLD N ++K+ DFG S ++ D +T CG+ NY APE+IS + Y+ P DIWS G ++ +L G F ++ + T K K F E ++++ +V +ML P R + KHE F
Sbjct: 31 GATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDG---EFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDE---HVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWF 280
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: AMPKalpha (gene:FBgn0023169 transcript:FBtr0070218) HSP 1 Score: 125.176 bits (313), Expect = 4.326e-30 Identity = 82/256 (32.03%), Postives = 128/256 (50.00%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYID---LLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFP-ADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELF 1603
G +G G+FGKV + + + + VK + S + I R I L H I+ Y V+ +++MEY+ G L + I K + Q +QII GV++ H + I+HRD+ P N+LLD N ++K+ DFG S ++ D +T CG+ NY APE+IS + Y+ P DIWS G ++ +L G F ++ + T K K F E ++++ +V +ML P R + KHE F
Sbjct: 31 GATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDG---EFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDE---HVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWF 280
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 135.191 bits (339), Expect = 3.122e-33 Identity = 86/257 (33.46%), Postives = 129/257 (50.19%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIE--NNINRYIDLLN---HERIVSYYGVVQKA--KKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-KTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
G+ +G+G+FG+V L +G E VK + D + + + I LL HERIV YYG ++ K I MEYMP GS+ + ++ ++ ++QI+EGV +LH N I+HRDI +NIL D+ N+KL DFG SR ++ K+ GT +++PE+IS + Y ADIWS+G T+ ML R + E + I P +S + + + K RP A LL+H
Sbjct: 357 GKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVSALECEIQLLKNLFHERIVQYYGCLRDTHEKTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICLSGTGIKSVTGTPYWMSPEVISGEGYGRKADIWSIGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPTLPPHVSDHCRDFLKRIFVETK--QRPAAEDLLRH 611
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 135.191 bits (339), Expect = 3.382e-33 Identity = 86/257 (33.46%), Postives = 129/257 (50.19%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIE--NNINRYIDLLN---HERIVSYYGVVQKA--KKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-KTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
G+ +G+G+FG+V L +G E VK + D + + + I LL HERIV YYG ++ K I MEYMP GS+ + ++ ++ ++QI+EGV +LH N I+HRDI +NIL D+ N+KL DFG SR ++ K+ GT +++PE+IS + Y ADIWS+G T+ ML R + E + I P +S + + + K RP A LL+H
Sbjct: 365 GKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVSALECEIQLLKNLFHERIVQYYGCLRDTHEKTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICLSGTGIKSVTGTPYWMSPEVISGEGYGRKADIWSIGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPTLPPHVSDHCRDFLKRIFVETK--QRPAAEDLLRH 619
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: stk24b (serine/threonine kinase 24b (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-040426-2841]) HSP 1 Score: 131.339 bits (329), Expect = 1.107e-32 Identity = 89/272 (32.72%), Postives = 142/272 (52.21%), Query Frame = 2
Query: 809 QDIYSKCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSS---RRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
Q++ + F K IG+GSFG+V +K + + + VV I+ +++ +I + I +L+ + YYG K K +I+MEY+ GS L+ +E S+ QI + ++I++G+E+LH + IHRDI +N+LL +KL DFG + + DT + TF GT ++APE+I Y ADIWS+G T + G + +++ I KN P L + + V+ LN +PS RPTA LLKH+L +
Sbjct: 14 QNLKADPEELFTKLERIGKGSFGEV--FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPG-SLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKR--NTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKN-----NPPTLEGNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIV 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: stk24b (serine/threonine kinase 24b (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-040426-2841]) HSP 1 Score: 130.954 bits (328), Expect = 1.152e-32 Identity = 88/262 (33.59%), Postives = 138/262 (52.67%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSS---RRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
F K IG+GSFG+V +K + + + VV I+ +++ +I + I +L+ + YYG K K +I+MEY+ GS L+ +E S+ QI + ++I++G+E+LH + IHRDI +N+LL +KL DFG + + DT + TF GT ++APE+I Y ADIWS+G T + G + +++ I KN P L + + V+ LN +PS RPTA LLKH+L +
Sbjct: 12 FTKLERIGKGSFGEV--FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPG-SLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKR--NTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKN-----NPPTLEGNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIV 263
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140]) HSP 1 Score: 127.872 bits (320), Expect = 1.244e-32 Identity = 81/273 (29.67%), Postives = 132/273 (48.35%), Query Frame = 2
Query: 818 YSKCSND---FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIE---NNINRYIDLLN---HERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-----KTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
+ CS D + KG +G+G++G V L G VK ++ S + E + + R +DLL H IV + G I MEY+P GS+ N + + + K + S+QI+EGV +LH N++IHRD+ +NI+L +KL DFG +R + T + K+ GT ++APE+I++ + +DIWS+G T+F M G+ + + +I + + + S V+ L RP+A LL+H
Sbjct: 11 FGSCSGDAITWTKGEVLGKGAYGTVYC-GLTSQGQLIAVKQVALDASTSEIAEKEYDRLEREVDLLKNLKHTNIVGFLGTALSENIVSIFMEYIPGGSISNILGQFGPLPEKVFVLYSQQILEGVAYLHANRVIHRDLKGNNIMLMPTGVVKLIDFGCARRLSCLQTSTGSKGDLLKSVHGTPYWMAPEVINETGHGRKSDIWSIGCTVFEMATGKPPLAHMNKMAALYYIGARRGLMPSLSDDFSTDAKDFVQACLTRDQRQRPSAEELLRH 282
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dennd1a (DENN domain containing 1A [Source:Xenbase;Acc:XB-GENE-5729862]) HSP 1 Score: 139.813 bits (351), Expect = 1.402e-34 Identity = 89/264 (33.71%), Postives = 139/264 (52.65%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNIN------RYIDLLNHERIVSYYGVVQKA--KKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-KTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKP--LELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
G+ +GRG+FG+V L + G E VK + D S+ +N + + L HERIV YYG ++ +K I +EYMP GS+ + ++ ++ ++QI++GV +LHGN I+HRDI +NIL D+ N+KL DFG S+ ++ K+ GT +++PE+IS + Y AD+WSV T+ ML + + E E + I K KP + S +K++ + RPTA LL+H LF+
Sbjct: 364 GKLLGRGAFGEVYLCYDVDKGRELAVKQVPFDPD-SQETSKEVNALECEIQLLKLHRHERIVQYYGCLRDPTERKLSIFVEYMPGGSIKDQLKAYGALTENVTRRYTRQILQGVSYLHGNMIVHRDIKGANILRDSAGNVKLGDFGASKRIQTICMSGTGIKSVTGTPYWMSPEVISGEGYGRKADVWSVACTVVEMLTEKPPWSE---YEAMAAIFKIATQPTKPRLPDTVSDACRDFMKQIF-VEEKRRPTAEELLRH-LFV 621
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dennd1a (DENN domain containing 1A [Source:Xenbase;Acc:XB-GENE-5729862]) HSP 1 Score: 139.813 bits (351), Expect = 1.438e-34 Identity = 89/264 (33.71%), Postives = 139/264 (52.65%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNIN------RYIDLLNHERIVSYYGVVQKA--KKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-KTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKP--LELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
G+ +GRG+FG+V L + G E VK + D S+ +N + + L HERIV YYG ++ +K I +EYMP GS+ + ++ ++ ++QI++GV +LHGN I+HRDI +NIL D+ N+KL DFG S+ ++ K+ GT +++PE+IS + Y AD+WSV T+ ML + + E E + I K KP + S +K++ + RPTA LL+H LF+
Sbjct: 357 GKLLGRGAFGEVYLCYDVDKGRELAVKQVPFDPD-SQETSKEVNALECEIQLLKLHRHERIVQYYGCLRDPTERKLSIFVEYMPGGSIKDQLKAYGALTENVTRRYTRQILQGVSYLHGNMIVHRDIKGANILRDSAGNVKLGDFGASKRIQTICMSGTGIKSVTGTPYWMSPEVISGEGYGRKADVWSVACTVVEMLTEKPPWSE---YEAMAAIFKIATQPTKPRLPDTVSDACRDFMKQIF-VEEKRRPTAEELLRH-LFV 614
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 133.265 bits (334), Expect = 1.157e-33 Identity = 86/259 (33.20%), Postives = 135/259 (52.12%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
F K IG+GSFG+V YK +++ + VV I+ +++ +I + I +L+ I YYG K K +I+MEY+ GS L+ + K + I + ++I++G+++LH + IHRDI +N+LL ++KL DFG + + DT + TF GT ++APE+I Y F ADIWS+G T + G + + ++ I KN + S+ V+ LN P +RPTA LLKH L
Sbjct: 7 FTKLERIGKGSFGEV--YKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLL-KPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKR--NTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQ--GQYSKPFKDFVEACLNKDPRSRPTARELLKHRFIL 258
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 133.65 bits (335), Expect = 1.268e-33 Identity = 86/259 (33.20%), Postives = 135/259 (52.12%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
F K IG+GSFG+V YK +++ + VV I+ +++ +I + I +L+ I YYG K K +I+MEY+ GS L+ + K + I + ++I++G+++LH + IHRDI +N+LL ++KL DFG + + DT + TF GT ++APE+I Y F ADIWS+G T + G + + ++ I KN + S+ V+ LN P +RPTA LLKH L
Sbjct: 7 FTKLERIGKGSFGEV--YKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLL-KPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKR--NTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQ--GQYSKPFKDFVEACLNKDPRSRPTARELLKHRFIL 258
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 133.65 bits (335), Expect = 1.472e-33 Identity = 86/259 (33.20%), Postives = 135/259 (52.12%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
F K IG+GSFG+V YK +++ + VV I+ +++ +I + I +L+ I YYG K K +I+MEY+ GS L+ + K + I + ++I++G+++LH + IHRDI +N+LL ++KL DFG + + DT + TF GT ++APE+I Y F ADIWS+G T + G + + ++ I KN + S+ V+ LN P +RPTA LLKH L
Sbjct: 7 FTKLERIGKGSFGEV--YKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLL-KPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKR--NTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQ--GQYSKPFKDFVEACLNKDPRSRPTARELLKHRFIL 258
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Aurkc (aurora kinase C [Source:MGI Symbol;Acc:MGI:1321119]) HSP 1 Score: 139.428 bits (350), Expect = 6.095e-37 Identity = 74/257 (28.79%), Postives = 138/257 (53.70%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
NDF GR +GRG FG+V L +L ++ +K + + +E+ + R +++ L H I+ Y + Y+++EY P G L +++ + +++ + +++ + + + H ++IHRDI P N+LL N +K++DFG+S V + + KT CGT++YL PE+I+ + Y+ D+W +G + +L+G+ F + E I +++DFK ++ ++L Y PS R + A +LKH
Sbjct: 14 NDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWS--VHTPSLRR--KTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRI---RQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKH 263
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Aurkc (aurora kinase C [Source:MGI Symbol;Acc:MGI:1321119]) HSP 1 Score: 139.428 bits (350), Expect = 6.095e-37 Identity = 74/257 (28.79%), Postives = 138/257 (53.70%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
NDF GR +GRG FG+V L +L ++ +K + + +E+ + R +++ L H I+ Y + Y+++EY P G L +++ + +++ + +++ + + + H ++IHRDI P N+LL N +K++DFG+S V + + KT CGT++YL PE+I+ + Y+ D+W +G + +L+G+ F + E I +++DFK ++ ++L Y PS R + A +LKH
Sbjct: 14 NDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWS--VHTPSLRR--KTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRI---RQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKH 263
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Aurkc (aurora kinase C [Source:MGI Symbol;Acc:MGI:1321119]) HSP 1 Score: 139.813 bits (351), Expect = 9.556e-37 Identity = 74/257 (28.79%), Postives = 138/257 (53.70%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
NDF GR +GRG FG+V L +L ++ +K + + +E+ + R +++ L H I+ Y + Y+++EY P G L +++ + +++ + +++ + + + H ++IHRDI P N+LL N +K++DFG+S V + + KT CGT++YL PE+I+ + Y+ D+W +G + +L+G+ F + E I +++DFK ++ ++L Y PS R + A +LKH
Sbjct: 53 NDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWS--VHTPSLRR--KTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRI---RQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKH 302
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Prkaa1 (protein kinase, AMP-activated, alpha 1 catalytic subunit [Source:MGI Symbol;Acc:MGI:2145955]) HSP 1 Score: 132.494 bits (332), Expect = 1.656e-32 Identity = 83/256 (32.42%), Postives = 131/256 (51.17%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYID---LLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFP-ADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELF 1603
G +G G+FGKV + K +GH+ VK + S + I R I L H I+ Y V+ +++MEY+ G L + I K + K+ + +QI+ GV++ H + ++HRD+ P N+LLDA+ N K+ DFG S ++ D +T CG+ NY APE+IS + Y+ P DIWS G ++ +L G F + + + I I + P L+ +S ++K ML P R + +HE F
Sbjct: 30 GDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG---EFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG--IFYTPQYLNPSVIS-LLKHMLQVDPMKRAAIKDIREHEWF 279
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Prkaa1 (protein kinase, AMP-activated, alpha 1 catalytic subunit [Source:MGI Symbol;Acc:MGI:2145955]) HSP 1 Score: 132.494 bits (332), Expect = 1.762e-32 Identity = 83/256 (32.42%), Postives = 131/256 (51.17%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYID---LLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFP-ADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELF 1603
G +G G+FGKV + K +GH+ VK + S + I R I L H I+ Y V+ +++MEY+ G L + I K + K+ + +QI+ GV++ H + ++HRD+ P N+LLDA+ N K+ DFG S ++ D +T CG+ NY APE+IS + Y+ P DIWS G ++ +L G F + + + I I + P L+ +S ++K ML P R + +HE F
Sbjct: 21 GDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG---EFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG--IFYTPQYLNPSVIS-LLKHMLQVDPMKRAAIKDIREHEWF 270
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|O22042|M3K3_ARATH (Mitogen-activated protein kinase kinase kinase 3 OS=Arabidopsis thaliana OX=3702 GN=ANP3 PE=1 SV=1) HSP 1 Score: 150.599 bits (379), Expect = 1.551e-37 Identity = 96/260 (36.92%), Postives = 142/260 (54.62%), Query Frame = 2
Query: 845 KGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDS---------RMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEK-SICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
KG IG G+FG+V + L SG +K I + R +E + + + L+H IV Y G V+++ ILME++P GS+ + +EK S II +KQ++ G+E+LH N I+HRDI +NIL+D I+L DFG S+ V + AT N AK+ GT ++APE+I +SF ADIWSVG T+ M G+ + E+ V I + K P +LS ++K L+ +PS R +A LL+H
Sbjct: 70 KGELIGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEV-QLLKNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANILVDNKGCIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMATGKPPWSEQYQQFAAVLHIGRTKAHPPIPEDLSPEAKDFLMK-CLHKEPSLRLSATELLQH 327
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|O22040|ANP1_ARATH (Mitogen-activated protein kinase kinase kinase ANP1 OS=Arabidopsis thaliana OX=3702 GN=ANP1 PE=1 SV=2) HSP 1 Score: 149.828 bits (377), Expect = 3.991e-37 Identity = 95/265 (35.85%), Postives = 143/265 (53.96%), Query Frame = 2
Query: 845 KGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDS---------RMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHE--KSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
KG+ IGRG+FG V + L SG VK I + + + +E + + + L+H IV Y G V++ IL+E++P GS+ + +EK + ++Q++ G+E+LH + I+HRDI +NIL+D IKL DFG S+ V + AT AK+ GT ++APE+I +SF ADIWSVG T+ M+ G+ + + K + I FI K P LSS ++K L P+ RPTA+ LLKH +
Sbjct: 71 KGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEV-KLLKNLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEVAAIF-FIGTTKSHPPIPDTLSSDAKDFLLK-CLQEVPNLRPTASELLKHPFVM 332
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9FZ36|M3K2_ARATH (Mitogen-activated protein kinase kinase kinase 2 OS=Arabidopsis thaliana OX=3702 GN=ANP2 PE=2 SV=1) HSP 1 Score: 146.747 bits (369), Expect = 4.052e-36 Identity = 94/261 (36.02%), Postives = 145/261 (55.56%), Query Frame = 2
Query: 845 KGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDS---------RMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHE--KSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
KG+ IGRG+FG V + L SG VK I ++ + + +E + + + L+H IV Y G V++ + IL+E++P GS+ + +EK + + + Q++ G+E+LH + I+HRDI +NIL+D IKL DFG S+ V + AT + AK+ GT ++APE+I +SF ADIWSVG T+ M+ G+ + + K I I I K P +SS ++K L +P+ RPTA+ LLKH
Sbjct: 70 KGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASKEKTQAHIQELEEEV-KLLKNLSHPNIVRYLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEIAAIF-HIGTTKSHPPIPDNISSDANDFLLK-CLQQEPNLRPTASELLKH 327
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|O88445|AURKC_MOUSE (Aurora kinase C OS=Mus musculus OX=10090 GN=Aurkc PE=1 SV=2) HSP 1 Score: 139.428 bits (350), Expect = 4.263e-36 Identity = 74/257 (28.79%), Postives = 138/257 (53.70%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDL---LNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
NDF GR +GRG FG+V L +L ++ +K + + +E+ + R +++ L H I+ Y + Y+++EY P G L +++ + +++ + +++ + + + H ++IHRDI P N+LL N +K++DFG+S V + + KT CGT++YL PE+I+ + Y+ D+W +G + +L+G+ F + E I +++DFK ++ ++L Y PS R + A +LKH
Sbjct: 14 NDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIHRDIKPENLLLGLNGEVKISDFGWS--VHTPSLRR--KTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRI---RQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKH 263
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|P92958|KIN11_ARATH (SNF1-related protein kinase catalytic subunit alpha KIN11 OS=Arabidopsis thaliana OX=3702 GN=KIN11 PE=1 SV=1) HSP 1 Score: 142.124 bits (357), Expect = 4.103e-35 Identity = 86/260 (33.08%), Postives = 137/260 (52.69%), Query Frame = 2
Query: 836 DFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLN---HERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFP-ADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELF 1603
++ G+ +G GSFGKV + + + +GH+ +K + +E + R I +L H I+ Y V++ Y++MEY+ G L + I + + + N +QII GVE+ H N ++HRD+ P N+LLD+ NIK+ DFG S V++D + KT CG+ NY APE+IS + Y+ P D+WS G ++ +L G F +++I + I I P LSS ++ ML P R T + +H F
Sbjct: 19 NYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDG---HFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKI--KGGIYTLPSHLSS-EARDLIPRMLIVDPVKRITIPEIRQHRWF 272
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A0H3YJG2 (Slc42a-1 OS=Schmidtea mediterranea OX=79327 GN=slc42a-1 PE=2 SV=1) HSP 1 Score: 230.335 bits (586), Expect = 5.805e-62 Identity = 139/407 (34.15%), Postives = 217/407 (53.32%), Query Frame = 2
Query: 386 PIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDRISRAFQVSNDFNLDQDIYSKCSNDFAKG-----RCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQ-NCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLL 1588
PI +AC++GH +IVK IK +C++++ + R +H + + +IVKLLIE+ I DS PIH AC V N+E A+LL+ N C + L K ++P+ IAE + +++K+I++ Q+ I+ Q+ + C F + +CI GS+G V LY + +F VK + +R IE NIN + +LL HERIV ++G K + YI MEY+ +K+ ++ +KQI+E + FLH IIHRDI P N+LLD + N+KL+DFG S ++ A CGT Y APEI++ + Y+ DIWS+GAT+ + G+ +H I+T I ++I++K E + +S ++ ML R +A LL
Sbjct: 542 PILYACKYGHRKIVKYFIKQKCNVDSFDCEFRRALHYAVISNNNDIVKLLIESGAAINVPDSLLMMPIHLACKVNNIEAAQLLMENNCDMVTLDKLKRSPLQIAETGDFENMIKLIKE---CQIIREIAAEMQLKCGKLCNHKF---CYTSFQRKKIKNRKCIASGSYGTVFLYNESGTDRKFAVKKIPKQNIRARYIEANINDFKNLLCHERIVKHFGAFHKKENHYIFMEYLDTLQKKKYQKKSPG----DLLLFAKQILEALSFLHERSIIHRDIKPENVLLDIDGNLKLSDFGLSLLLSSVAEDIQKEGRCCGTYCYAAPEILNAELYTCSVDIWSLGATMIQLCTGQPPYHNLGDGAIITVISTTREIEYKLPEYMPKYISNLIDHMLEKDQYKRLSAKKLL 938 HSP 2 Score: 68.1662 bits (165), Expect = 3.954e-8 Identity = 43/153 (28.10%), Postives = 76/153 (49.67%), Query Frame = 2
Query: 86 FDYFMSKVKLGIIDEVKISFMPEYLN-KIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIE 541
F + +K G I++VK + L K+ PI AC+ GH ++VK+ I + ++S R + +A + + D++ +LI++ IN D PIH AC+ + E +LL++N CD+ P+ I+ N++KL+ E
Sbjct: 507 FGQLIKAIKDGSIEDVKKYYSRRILEIKLGSYSRSPILYACKYGHRKIVKYFIKQKCNVDSFDCEFRRALHYAVISNNNDIVKLLIESGAAINVPDSLLMMPIHLACKVNNIEAAQLLMENNCDMVTLDKLKRSPLQIAETGDFENMIKLIKE 659
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A0S4J9E8 (Ankyrin repeat-containing protein kinase, putative OS=Bodo saltans OX=75058 GN=BSAL_13820 PE=4 SV=1) HSP 1 Score: 174.481 bits (441), Expect = 2.048e-42 Identity = 143/579 (24.70%), Postives = 237/579 (40.93%), Query Frame = 2
Query: 167 IDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIE----------------------ACGHD------------------DLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKV------------------------------------IQDELKRQLFDRISRAFQ---VSNDFNLDQDIY--------------SKCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCI-EKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFIL----KNKKIDFKPLELSSRR--MSTIVKEMLNYKPSNRPTAASLLKHELF 1603
+ N IH+A GH +V++ L KG I + P+ A N H VL L++ +I+A D+N P+H A GH +V L+ D E CGH + P+H++ GH N+V L+ +++A IH A G+ +V RLL ++ +N TP+ IA +T +K I++ K D +++ F N + Q+I+ S S F+K +G G++G V K G K D+ M+ R + L+H IV + + ILME++P G + NCI E+ + + + + K +EG+ +LH I+H D+ P+N+LL ++KLTDFG +R ++ T G++ YLAPE + YSF +DIW++G + HM+ + +++ + +L K K+ + ++LS + + +++ L P RP+AA LL H LF
Sbjct: 653 VTKNGAAAIHLAAHGGHAQVIRLLASKGGNINATTNDKVTPLNIAAANGHTQVLEELLERNAKIDAADENGTTPLHIAAVCGHVHVVAALLDAIKDDELPQHNPVFAEDSNGRTALHLAAQCGHRRVVLLLLVRSAVDSTDAFGMTPLHVAATNGHMNVVIALLAGGADVKAVMKDGATAIHLAAQEGHAKVIRLLANKGGNINATRNDNVTPLYIAAVNGHTLAVKALLDHHADVSAGMKDGATAKAAAVRGGHVAIVSLLAKIEENHKNAGRDGVAQPFASPTAGNGLVVLQEIFDFDEIDLADSDRQPSFVSGRFSKSYKLGAGAYGTVYRAWDSKEGRHVACKEG---CDEKEMLREY--RVLKELDHVNIVKAFDFEAHEGRGRILMEWVPSGCVYNCIVERDLDV--QLVSKYVKAALEGLAYLHSEGIVHGDLKPANMLLTTEGSVKLTDFGTARKLEPQQDYYTVATAVGSLPYLAPESVRCGVYSFGSDIWAIGCSALHMISRTIPWDDEANTHVSLHLLLGGMKTLKLPKRLVDLSEKEGNLRSLIISTLAIDPKQRPSAAELLCHSLF 1224 HSP 2 Score: 109.768 bits (273), Expect = 3.857e-21 Identity = 57/202 (28.22%), Postives = 95/202 (47.03%), Query Frame = 2
Query: 191 IHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDRISRAFQVSND 796
IH A + GH +V++ L G K+ + R P+ A N H L+ L++ N D+N P+H A +GH ++V L+ + D+ A + IH++ GH +++LL NI A + K P++ A G+ +V L+ +D + +N TP++IA DV+ R L R + V+ND
Sbjct: 363 IHYATQGGHAKVIRLLAKSGGKVNAKRNDKVTPLQIAAANGHTKALVELLQLEASANVADENGTTPLHAAAVYGHVDVVTALLVDGADVAAVTKNGAAAIHVAAHGGHAQVIRLLANKGGNINATRNDKVTPLYIAAANGHTQVLEELLELSAKIDAVDENGTTPLHIAAANGRLDVV--------RALLARKADVAAVAND 556 HSP 3 Score: 103.219 bits (256), Expect = 3.868e-19 Identity = 51/190 (26.84%), Postives = 97/190 (51.05%), Query Frame = 2
Query: 167 IDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTL-DMLTKNNKTPINIAEQYRYTDVMKVI 733
+ N IHVA GH +V++ L +KG I + R P++ A N H VL L++ +I+A+D+N P+H A G ++V+ L+ + D+ A +D IH + HT +++LL ++ + A+ ++ P+ A +G + L+ + + ++ +N TP++ A Y + DV+ +
Sbjct: 454 VTKNGAAAIHVAAHGGHAQVIRLLANKGGNINATRNDKVTPLYIAAANGHTQVLEELLELSAKIDAVDENGTTPLHIAAANGRLDVVRALLARKADVAAVANDGATAIHYAVYGDHTEVIRLLAKSGGKVNAKRKNQVTPLQIAAAIGRTKALEELLQLEENIVNVADENGITPLHAAAVYGHVDVVTAL 643 HSP 4 Score: 100.138 bits (248), Expect = 4.359e-18 Identity = 55/231 (23.81%), Postives = 102/231 (44.16%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINA----------------------------------LDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELK 748
++ +D N P+H+A NG +VV+ L+ + A + + G I +A + H +V+ +L K+ ++NA D+N P+H A +GH ++V L+ + D+ A + IH++ GH +++LL NI A + K P++ A G+ +V L+ +D +N TP++IA + V+ + D +K
Sbjct: 517 IDAVDENGTTPLHIAAANGRLDVVRALLARKADVAAVANDGATAIHYAVYGDHTEVIRLLAKSGGKVNAKRKNQVTPLQIAAAIGRTKALEELLQLEENIVNVADENGITPLHAAAVYGHVDVVTALLADGADVAAVTKNGAAAIHLAAHGGHAQVIRLLASKGGNINATTNDKVTPLNIAAANGHTQVLEELLERNAKIDAADENGTTPLHIAAVCGHVHVVAALLDAIK 747 HSP 5 Score: 97.0561 bits (240), Expect = 3.884e-17 Identity = 49/182 (26.92%), Postives = 94/182 (51.65%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
P+ +A NGH + + L+ A + G P+ A H DV+ L+ + ++ A+ +N IH A GH ++++LL +I A +D + P++I+ GHT +++ L+E + I+A D + P+H A G ++V R L+ K + + + T I+ A +T+V++++
Sbjct: 395 PLQIAAANGHTKALVELLQLEASANVADENGTTPLHAAAVYGHVDVVTALLVDGADVAAVTKNGAAAIHVAAHGGHAQVIRLLANKGGNINATRNDKVTPLYIAAANGHTQVLEELLELSAKIDAVDENGTTPLHIAAANGRLDVVRALLARKADVAAVANDGATAIHYAVYGDHTEVIRLL 576 HSP 6 Score: 95.5153 bits (236), Expect = 1.102e-16 Identity = 54/185 (29.19%), Postives = 87/185 (47.03%), Query Frame = 2
Query: 161 NKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYT 715
N D N P+H A GH +VV L+ GA + + K G I A H V+ +L INA +K P++ A GH ++++ L++ I+A + P+HI+ G ++V+ L+ ++ A + IH+A Y + EV RLL + ++ KN TP+ IA T
Sbjct: 419 NVADENGTTPLHAAAVYGHVDVVTALLVDGADVAAVTKNGAAAIHVAAHGGHAQVIRLLANKGGNINATRNDKVTPLYIAAANGHTQVLEELLELSAKIDAVDENGTTPLHIAAANGRLDVVRALLARKADVAAVANDGATAIHYAVYGDHTEVIRLLAKSGGKVNAKRKNQVTPLQIAAAIGRT 603 HSP 7 Score: 94.3597 bits (233), Expect = 2.601e-16 Identity = 51/214 (23.83%), Postives = 98/214 (45.79%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEA----------------------------------CGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMK 727
P+++A NGH +V++ L++ AKI++ + G P+ A N DV+ L+ + ++ A+ + IH+A H E+++LL K+ + A + + P+H + YGH ++V L+ + ++ A + IH A + G+ +V RLL + ++ T + TP+NIA +T V++
Sbjct: 494 PLYIAAANGHTQVLEELLELSAKIDAVDENGTTPLHIAAANGRLDVVRALLARKADVAAVANDGATAIHYAVYGDHTEVIRLLAKSGGKVNAKRKNQVTPLQIAAAIGRTKALEELLQLEENIVNVADENGITPLHAAAVYGHVDVVTALLADGADVAAVTKNGAAAIHLAAHGGHAQVIRLLASKGGNINATTNDKVTPLNIAAANGHTQVLE 707 HSP 8 Score: 91.6633 bits (226), Expect = 2.234e-15 Identity = 50/178 (28.09%), Postives = 80/178 (44.94%), Query Frame = 2
Query: 191 IHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVM 724
IH+A + GH +V+K L G I + R P+ A N H L L++ N D+N P+H A G+ + V L+ D+ A +D IH + H I++LL NI A + K P+ A G + L+ + T+++ +N TP++ A DV+
Sbjct: 165 IHLAAQEGHADVIKLLASSGGNINATRNDKVTPLQIAAANGHTKALEELLRLEATANVADENGTTPLHAAAADGNMDAVTALLARDADVAAVTNDGTTAIHHAVFADHAEIIRLLANKGGNINAARNDKVTPLQIAAANGRTKALEELLRLEATVNVADENGTTPLHAAAANGRLDVV 342 HSP 9 Score: 87.4261 bits (215), Expect = 3.768e-14 Identity = 54/191 (28.27%), Postives = 93/191 (48.69%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNK-TPINIAEQYRYTDVMK 727
+N D N P+H A NG +VV L+ GA + + K G I +A H V+ +L K+ ++NA +K P+ A GH + + L++ + P+H + YGH ++V L+ + ++ A + IH A + G+ +V RLL ++ T+N+K TP+ IA +T V++
Sbjct: 319 VNVADENGTTPLHAAAANGRLDVVSDLLADGADVAAVAKDGSTAIHYATQGGHAKVIRLLAKSGGKVNAKRNDKVTPLQIAAANGHTKALVELLQLEASANVADENGTTPLHAAAVYGHVDVVTALLVDGADVAAVTKNGAAAIHVAAHGGHAQVIRLLANKGGNINA-TRNDKVTPLYIAAANGHTQVLE 508 HSP 10 Score: 83.1889 bits (204), Expect = 8.999e-13 Identity = 44/185 (23.78%), Postives = 94/185 (50.81%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
P+ +A NG + ++ L+ A + + G P+ A N DV+ L+ + ++ A+ ++ IH+A + GH ++++LL K+ + A +D + P+ I+ GHT + L++ + D + P+H A G+V+V L+ + + +TKN I++A + V++++ ++
Sbjct: 296 PLQIAAANGRTKALEELLRLEATVNVADENGTTPLHAAAANGRLDVVSDLLADGADVAAVAKDGSTAIHYATQGGHAKVIRLLAKSGGKVNAKRNDKVTPLQIAAANGHTKALVELLQLEASANVADENGTTPLHAAAVYGHVDVVTALLVDGADVAAVTKNGAAAIHVAAHGGHAQVIRLLANK 480 HSP 11 Score: 82.4185 bits (202), Expect = 1.609e-12 Identity = 46/190 (24.21%), Postives = 83/190 (43.68%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMK 727
L+ D N +H A NG ++ V L+ GA +++ K G I A H DV+ +L + INA +K P+ A GH + ++ L++ + P+H + G+ + V L+ + ++ A + IH A + + E+ RLL ++ + TP+ IA T ++
Sbjct: 121 LDAADENGTTSLHTAVANGRKDAVTALLAGGADVKAVMKDGATAIHLAAQEGHADVIKLLASSGGNINATRNDKVTPLQIAAANGHTKALEELLRLEATANVADENGTTPLHAAAADGNMDAVTALLARDADVAAVTNDGTTAIHHAVFADHAEIIRLLANKGGNINAARNDKVTPLQIAAANGRTKALE 310 HSP 12 Score: 82.0333 bits (201), Expect = 2.124e-12 Identity = 46/181 (25.41%), Postives = 86/181 (47.51%), Query Frame = 2
Query: 191 IHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
IH A H E+++ L +KG I + R P+ A N L L++ +N D+N P+H A G ++V L+ + D+ A D IH + + GH +++LL ++ + A+ + K P+ A G+ + L+ + + ++ +N TP++ A Y + DV+ +
Sbjct: 264 IHHAVFADHAEIIRLLANKGGNINAARNDKVTPLQIAAANGRTKALEELLRLEATVNVADENGTTPLHAAAANGRLDVVSDLLADGADVAAVAKDGSTAIHYATQGGHAKVIRLLAKSGGKVNAKRNDKVTPLQIAAANGHTKALVELLQLEASANVADENGTTPLHAAAVYGHVDVVTAL 444 HSP 13 Score: 80.1073 bits (196), Expect = 9.273e-12 Identity = 52/235 (22.13%), Postives = 97/235 (41.28%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIE---------------------------NNCN-------------IEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
+N D N P+H A GH +VV L+ GA + + K G I A H V+ +L INA +K P++ A GH ++++ L++ I+A + P+HI+ GH ++V L++ C +++ D+ P+H A G++ V L+ + + K+ T I++A Q + V++++ ++
Sbjct: 617 VNVADENGITPLHAAAVYGHVDVVTALLADGADVAAVTKNGAAAIHLAAHGGHAQVIRLLASKGGNINATTNDKVTPLNIAAANGHTQVLEELLERNAKIDAADENGTTPLHIAAVCGHVHVVAALLDAIKDDELPQHNPVFAEDSNGRTALHLAAQCGHRRVVLLLLVRSAVDSTDAFGMTPLHVAATNGHMNVVIALLAGGADVKAVMKDGATAIHLAAQEGHAKVIRLLANK 851 HSP 14 Score: 71.2478 bits (173), Expect = 4.323e-9 Identity = 35/163 (21.47%), Postives = 79/163 (48.47%), Query Frame = 2
Query: 254 KIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
++++ + G + A N KD + L+ ++ A+ ++ IH A + GH +++KLL + +I A +D + P+ I+ GHT ++ L+ D + P+H A GN++ L+ + +T + T I+ A + ++++++ ++
Sbjct: 120 ELDAADENGTTSLHTAVANGRKDAVTALLAGGADVKAVMKDGATAIHLAAQEGHADVIKLLASSGGNINATRNDKVTPLQIAAANGHTKALEELLRLEATANVADENGTTPLHAAAADGNMDAVTALLARDADVAAVTNDGTTAIHHAVFADHAEIIRLLANK 282
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: K1PKP1 (Mitogen-activated protein kinase kinase kinase 2 OS=Crassostrea gigas OX=29159 GN=CGI_10008499 PE=4 SV=1) HSP 1 Score: 158.303 bits (399), Expect = 5.173e-40 Identity = 94/286 (32.87%), Postives = 146/286 (51.05%), Query Frame = 2
Query: 785 VSNDFNLDQDIYS----------KCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIE------TDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
+ + +LD +Y+ +C ++ G +G G+FG+V + +G + +K +E + + R +EN I+ + HERIVSY+G Q + YI MEY+P GS+ + I K S+ +KQ++EG+ +LH N I+HRDI +NIL D N NIKL DFG S+ ++ + + GT ++APE+I+ + Y ADIWSVG TI ML + + E + I K+ F S ++ + + PS RPTA LL H
Sbjct: 36 IKRNSDLDSPVYALADLSLSKSPRCPVNWKAGALLGSGAFGEVYVCHDKDTGRDLAMKVVRLEQMNAETSKEVRALENEIH-LLRNFEHERIVSYFGCAQDKQSLYIFMEYLPGGSVKDEITKYGSLTENVSRKYTKQMLEGLAYLHKNVIVHRDIKGANILRDGNGNIKLGDFGASKRLQTIVSATGLHSVVGTPYWMAPEVINGEGYGRKADIWSVGCTIVEMLTTKPPWAEFESMAALYKIAMEKRPHFTLPNHISELCHDVLSKAFDRNPSTRPTAIDLLGH 320
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A182GGY8 (ANK_REP_REGION domain-containing protein OS=Aedes albopictus OX=7160 GN=RP20_CCG009719 PE=4 SV=1) HSP 1 Score: 166.392 bits (420), Expect = 1.112e-39 Identity = 72/182 (39.56%), Postives = 122/182 (67.03%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
P+H+AC+NGH+EVV+ LI A IE+ + W P+ FAC N HK+V+ ILI+ + I AL+Q+ W P+H +CR GH E+V++LI+ + +IEA D+ P+H++C+ GH +V++LI NIEA + + P+H A + G+ +V +LI K ++ L + N TP+++A + + +V++++
Sbjct: 1402 PLHLACQNGHKEVVEILIRGKANIEALNQVNWTPLHFACHNGHKEVVEILIREKVNIEALNQDNWTPLHLSCRHGHKEVVEILIREKVNIEALNQDNWTPLHLACQDGHKEVVEILIREEANIEALNQYNYTPLHIASWNGHEKVVEILIREKANIEALGQENWTPLHLACRNGHKEVVEIL 1583 HSP 2 Score: 166.007 bits (419), Expect = 1.594e-39 Identity = 74/182 (40.66%), Postives = 119/182 (65.38%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
P+H+AC+NGH+EVV+ LI + A I++ + P+ AC N HK+V+ ILI+ + I AL+Q W P+H+AC GH E+V++LI+ + +IEA D+ P+H+SCR+GH +V++LI NIEA + W P+H AC G+ EV +LI + ++ L + N TP++IA + V++++
Sbjct: 1369 PLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILIRGKANIEALNQVNWTPLHFACHNGHKEVVEILIREKVNIEALNQDNWTPLHLSCRHGHKEVVEILIREKVNIEALNQDNWTPLHLACQDGHKEVVEILIREEANIEALNQYNYTPLHIASWNGHEKVVEIL 1550 HSP 3 Score: 163.696 bits (413), Expect = 9.039e-39 Identity = 72/185 (38.92%), Postives = 121/185 (65.41%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
P+H+AC++GH+EVV+ LI + A IE+ ++ + P+ A +N H+ V+ ILI+ + I AL Q W P+H ACR GH E+V++LI+ + +IEA D+ P+H +C+ GH +V++L++ NI+A K+ P+H AC G+ EV +LI K +D LT+ TP+++A Q + +V++++ E
Sbjct: 1501 PLHLACQDGHKEVVEILIREEANIEALNQYNYTPLHIASWNGHEKVVEILIREKANIEALGQENWTPLHLACRNGHKEVVEILIRGKANIEALTQDNWTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILVGE 1685 HSP 4 Score: 160.229 bits (404), Expect = 1.559e-37 Identity = 71/181 (39.23%), Postives = 116/181 (64.09%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKV 730
P+H+AC NGH+EVV+ LI A IE+ + W P+ AC N H +V+ IL+K + I+AL + K+ P+H AC+ GH E+V++LI + +I+A P+H++C+ GH +V++L+ NIEA + W P+H AC G+ EV ++LI K +D LT+ TP+++A Q + +V+++
Sbjct: 1567 PLHLACRNGHKEVVEILIRGKANIEALTQDNWTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILVGEKANIEALNQDNWTPLHLACEKGHKEVVKILIGEKANIDALTQKKNTPLHLACQRGHKEVVEI 1747 HSP 5 Score: 159.458 bits (402), Expect = 2.447e-37 Identity = 76/197 (38.58%), Postives = 122/197 (61.93%), Query Frame = 2
Query: 152 EYLNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
E LN+++ P+H AC NGH+EVV+ LI + IE+ + W P+ +C + HK+V+ ILI+ + I AL+Q+ W P+H AC+ GH E+V++LI+ +IEA + P+HI+ GH +V++LI NIEA W P+H AC G+ EV +LI K ++ LT++N TP++ A Q + +V++++ E
Sbjct: 1426 EALNQVNWT---PLHFACHNGHKEVVEILIREKVNIEALNQDNWTPLHLSCRHGHKEVVEILIREKVNIEALNQDNWTPLHLACQDGHKEVVEILIREEANIEALNQYNYTPLHIASWNGHEKVVEILIREKANIEALGQENWTPLHLACRNGHKEVVEILIRGKANIEALTQDNWTPLHKACQNGHAEVVEILVKE 1619 HSP 6 Score: 158.688 bits (400), Expect = 4.134e-37 Identity = 71/185 (38.38%), Postives = 118/185 (63.78%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
P+H+A NGHE+VV+ LI + A IE+ + W P+ AC N HK+V+ ILI+ + I AL Q+ W P+H AC+ GH E+V++L+K + +I+A P+H++C+ GH +V++LI NI+A K P+H AC G+ EV +L+ K ++ L ++N TP+++A + + +V+K++ E
Sbjct: 1534 PLHIASWNGHEKVVEILIREKANIEALGQENWTPLHLACRNGHKEVVEILIRGKANIEALTQDNWTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILVGEKANIEALNQDNWTPLHLACEKGHKEVVKILIGE 1718 HSP 7 Score: 157.918 bits (398), Expect = 9.033e-37 Identity = 72/192 (37.50%), Postives = 120/192 (62.50%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
++ + N P+H AC+NG +EVV+ LI + A IE+ + W P+ AC N HK+V+ ILIK I+AL ++K+ P+H AC GH E V++LI + +I+A + P+H +C+ GH +V++L++ NI+A K+ P+H AC G+ EV +LI K +D LT+ TP+++A Q + +V++++
Sbjct: 1227 IDALAKNKSTPLHFACQNGRKEVVEILIREKANIEALNQHNWTPLHLACQNGHKEVVEILIKENANIDALTEHKYTPLHLACARGHKEAVQILIGEKANIDALDENKFTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEIL 1418 HSP 8 Score: 154.836 bits (390), Expect = 8.496e-36 Identity = 69/185 (37.30%), Postives = 116/185 (62.70%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
P+H++C +GH+EVV+ LI + IE+ + W P+ AC + HK+V+ ILI+ I AL+Q + P+H A GH ++V++LI+ + +IEA G ++ P+H++CR GH +V++LI NIEA W P+H AC G+ EV +L+ K +D L + TP+++A Q + +V++++ E
Sbjct: 1468 PLHLSCRHGHKEVVEILIREKVNIEALNQDNWTPLHLACQDGHKEVVEILIREEANIEALNQYNYTPLHIASWNGHEKVVEILIREKANIEALGQENWTPLHLACRNGHKEVVEILIRGKANIEALTQDNWTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGE 1652 HSP 9 Score: 154.066 bits (388), Expect = 1.586e-35 Identity = 71/192 (36.98%), Postives = 121/192 (63.02%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
++ +D N P+H AC+NGH EVV+ L+ + A I++ + + P+ AC N HK+V+ ILI + I+AL + K P+H AC+ GH E+V++LI+ + +IEA + P+H +C GH +V++LI NIEA + W P+H +C G+ EV +LI K ++ L ++N TP+++A Q + +V++++
Sbjct: 1326 IDALDENKFTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILIRGKANIEALNQVNWTPLHFACHNGHKEVVEILIREKVNIEALNQDNWTPLHLSCRHGHKEVVEILIREKVNIEALNQDNWTPLHLACQDGHKEVVEIL 1517 HSP 10 Score: 153.68 bits (387), Expect = 2.069e-35 Identity = 68/182 (37.36%), Postives = 116/182 (63.74%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
P+H+AC+NGH+EVV+ LI + A I++ + + P+ AC HK+ + ILI + I+ALD+NK+ P+H AC+ GH E+V++L+K + +I+A P+H++C+ GH +V++LI NI+A K P+H AC G+ EV +LI K ++ L + N TP++ A + +V++++
Sbjct: 1270 PLHLACQNGHKEVVEILIKENANIDALTEHKYTPLHLACARGHKEAVQILIGEKANIDALDENKFTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILIRGKANIEALNQVNWTPLHFACHNGHKEVVEIL 1451 HSP 11 Score: 151.754 bits (382), Expect = 8.724e-35 Identity = 70/187 (37.43%), Postives = 114/187 (60.96%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELK 748
P+H AC+NGH EVV+ L+ + A I++ + + P+ AC N HK+V+ ILI + I+AL + K P+H AC+ GH E+V++L+ + +IEA D+ P+H++C GH +VK+LI NI+A K P+H AC G+ EV + + + L TP+N+A Q +T+V K+++++ K
Sbjct: 1600 PLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILVGEKANIEALNQDNWTPLHLACEKGHKEVVKILIGEKANIDALTQKKNTPLHLACQRGHKEVVEIFLRKNANIAALDDEKCTPLNLASQNGHTEVEKIMKEKAK 1786 HSP 12 Score: 149.828 bits (377), Expect = 3.915e-34 Identity = 65/182 (35.71%), Postives = 119/182 (65.38%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
P+H+AC GH+E V+ LI + A I++ + + P+ AC N H +V+ IL+K + I+AL + K+ P+H AC+ GH E+V++LI + +I+A P+H++C+ GH +V++LI NIEA + W P+H+AC+ G+ EV +LI K ++ L ++N TP++++ ++ + +V++++
Sbjct: 1303 PLHLACARGHKEAVQILIGEKANIDALDENKFTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILIRGKANIEALNQVNWTPLHFACHNGHKEVVEILIREKVNIEALNQDNWTPLHLSCRHGHKEVVEIL 1484 HSP 13 Score: 149.828 bits (377), Expect = 4.213e-34 Identity = 74/195 (37.95%), Postives = 118/195 (60.51%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
+N D N P+H AC +G +EVV+ LI A I++ K P+ FAC N K+V+ ILI+ + I AL+Q+ W P+H AC+ GH E+V++LIK +I+A P+H++C GH V++LI NI+A D +K+ P+H AC G+ EV +L+ K +D L + TP+++A Q + +V++++ E
Sbjct: 1194 VNAADTNEYTPLHWACISGVKEVVEILIGGKANIDALAKNKSTPLHFACQNGRKEVVEILIREKANIEALNQHNWTPLHLACQNGHKEVVEILIKENANIDALTEHKYTPLHLACARGHKEAVQILIGEKANIDALDENKFTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGE 1388 HSP 14 Score: 146.362 bits (368), Expect = 6.073e-33 Identity = 76/231 (32.90%), Postives = 134/231 (58.01%), Query Frame = 2
Query: 53 FSQNLFLKMIDFDYFMSKVKLGIIDEVK-ISFMPEYLNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
F ++ F K ID GII+EVK + +N + +H++ +GH +V+ L+D GA + + + P+ +AC + K+V+ ILI + I+AL +NK P+H+AC+ G E+V++LI+ + +IEA + P+H++C+ GH +V++LI+ N NI+A K+ P+H AC G+ E ++LI K +D L +N TP++ A Q + +V++++ E
Sbjct: 1125 FPEHAFTKDIDGPLMHIAAGDGIIEEVKRLINNGANVNAPSVAGYTALHISASSGHRPIVELLLDNGANVNAADTNEYTPLHWACISGVKEVVEILIGGKANIDALAKNKSTPLHFACQNGRKEVVEILIREKANIEALNQHNWTPLHLACQNGHKEVVEILIKENANIDALTEHKYTPLHLACARGHKEAVQILIGEKANIDALDENKFTPLHKACQNGHAEVVEILVKE 1355 HSP 15 Score: 93.9745 bits (232), Expect = 3.912e-16 Identity = 62/188 (32.98%), Postives = 97/188 (51.60%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNC-----HKDVLMILIKNRCEINALDQNKWQPI-HWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
P+++A GH EVV LI+K + +F R I + F H V ++K + +A ++ P+ H A G E VK LI N ++ A +HIS GH IV+LL++N N+ A D++++ P+HWAC G EV +LI K +D L KN TP++ A Q +V++++
Sbjct: 1072 PLNLAAARGHTEVVILLIEKLIE-----QFPSRNIIDSAFQTAVQYGHSSV-QDMLKRKFPEHAFTKDIDGPLMHIAAGDGIIEEVKRLINNGANVNAPSVAGYTALHISASSGHRPIVELLLDNGANVNAADTNEYTPLHWACISGVKEVVEILIGGKANIDALAKNKSTPLHFACQNGRKEVVEIL 1253 HSP 16 Score: 63.1586 bits (152), Expect = 1.860e-6 Identity = 45/163 (27.61%), Postives = 83/163 (50.92%), Query Frame = 2
Query: 350 CEINALDQNKW-QPIHWACRFGHWEIVKLLIKNRCD------IEACG-HDD------LRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDR--ISRAFQVS 790
CE NA++ K+ P + R +++K+ I+N D I C H D L + + YGH N+V++L+E +I R++ W +H+A + + +++ LI ++ T+ KTP+N+A +T+V+ ++ ++L Q R I AFQ +
Sbjct: 947 CECNAVELLKYVLPQIYFFRPNGTKMLKIAIENGSDKICAYLINDCKVHPDVKFDGGLAALIWAVIYGHKNLVRILLEKGADINIRNTEGWSALHYAVHHKRIAISKFLIDKGINVNYQTREGKTPLNLAAARGHTEVVILLIEKLIEQFPSRNIIDSAFQTA 1109
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A182GJR2 (Uncharacterized protein OS=Aedes albopictus OX=7160 GN=RP20_CCG011139 PE=4 SV=1) HSP 1 Score: 165.622 bits (418), Expect = 2.189e-39 Identity = 76/185 (41.08%), Postives = 122/185 (65.95%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
P+H ACENGH+EV++ LI + A I++ + P+ +AC N HK+V+ ILI+ + I+AL + K+ P+H+ACR GH EIVK LI+ + +I+A H++ P+H +CR GH IV++L+ N NI+A + P+HWAC G+ EV + L+ K +D LT N TP++ A + + +V++++ E
Sbjct: 1506 PLHFACENGHKEVIEILIKEKANIDALTHKNFTPLHWACRNGHKEVVEILIRGKANIDALAEKKFTPLHFACRNGHKEIVKKLIRKKANIDALTHENFTPLHWACRNGHREIVEILVRKNSNIDALTHRNFTPLHWACRNGHKEVVKTLLREKANIDALTHKNSTPLHWACRNGHKEVVEILIKE 1690 HSP 2 Score: 159.073 bits (401), Expect = 2.844e-37 Identity = 75/185 (40.54%), Postives = 112/185 (60.54%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
P+H C NGH+EVVK LI A I++ + + P+ FAC N HK+V+ ILIK + I+AL + P+HWACR GH E+V++LI+ + +I+A P+H +CR GH IVK LI NI+A + P+HWAC G+ E+ +L+ +D LT N TP++ A + + +V+K + E
Sbjct: 1473 PLHWTCRNGHKEVVKILIRGKASIDALAENKFTPLHFACENGHKEVIEILIKEKANIDALTHKNFTPLHWACRNGHKEVVEILIRGKANIDALAEKKFTPLHFACRNGHKEIVKKLIRKKANIDALTHENFTPLHWACRNGHREIVEILVRKNSNIDALTHRNFTPLHWACRNGHKEVVKTLLRE 1657 HSP 3 Score: 156.762 bits (395), Expect = 2.150e-36 Identity = 69/180 (38.33%), Postives = 111/180 (61.67%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMK 727
P+H+ACE GH+EVV+ I + A IE+ + + P+ AC N HK+V+ ILIK + I+AL + P+HW CR GH E+VK+LI+ + I+A + P+H +C GH ++++LI+ NI+A + P+HWAC G+ EV +LI K +D L + TP++ A + + +++K
Sbjct: 1407 PLHLACEKGHKEVVEIFIREKANIEALAENKFTPLHLACVNGHKEVVEILIKEKANIDALTHKNFTPLHWTCRNGHKEVVKILIRGKASIDALAENKFTPLHFACENGHKEVIEILIKEKANIDALTHKNFTPLHWACRNGHKEVVEILIRGKANIDALAEKKFTPLHFACRNGHKEIVK 1586 HSP 4 Score: 155.992 bits (393), Expect = 3.870e-36 Identity = 70/182 (38.46%), Postives = 120/182 (65.93%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
P+H+AC NGH+EVV+ LI + A I++ + P+ + C N HK+V+ ILI+ + I+AL +NK+ P+H+AC GH E++++LIK + +I+A H + P+H +CR GH +V++LI NI+A K+ P+H+AC G+ E+ + LI K +D LT N TP++ A + + ++++++
Sbjct: 1440 PLHLACVNGHKEVVEILIKEKANIDALTHKNFTPLHWTCRNGHKEVVKILIRGKASIDALAENKFTPLHFACENGHKEVIEILIKEKANIDALTHKNFTPLHWACRNGHKEVVEILIRGKANIDALAEKKFTPLHFACRNGHKEIVKKLIRKKANIDALTHENFTPLHWACRNGHREIVEIL 1621 HSP 5 Score: 153.295 bits (386), Expect = 2.317e-35 Identity = 72/182 (39.56%), Postives = 117/182 (64.29%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
P+H AC+NGH+E+V+ LI + A I+S + P+ AC HK+V+ I I+ + I AL +NK+ P+H AC GH E+V++LIK + +I+A H + P+H +CR GH +VK+LI +I+A +K+ P+H+AC G+ EV +LI K +D LT N TP++ A + + +V++++
Sbjct: 1374 PLHFACQNGHKELVEILIRENANIDSEAQNKITPLHLACEKGHKEVVEIFIREKANIEALAENKFTPLHLACVNGHKEVVEILIKEKANIDALTHKNFTPLHWTCRNGHKEVVKILIRGKASIDALAENKFTPLHFACENGHKEVIEILIKEKANIDALTHKNFTPLHWACRNGHKEVVEIL 1555 HSP 6 Score: 152.14 bits (383), Expect = 7.287e-35 Identity = 74/211 (35.07%), Postives = 128/211 (60.66%), Query Frame = 2
Query: 116 GIIDEVKISFMPEYLN--KIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
G+ + V+I F+ E +N D + P+H+AC GH+EVV+ L+ + A I++ P+ FAC N HK+++ ILI+ I++ QNK P+H AC GH E+V++ I+ + +IEA + P+H++C GH +V++LI+ NI+A + P+HW C G+ EV ++LI K ++D L +N TP++ A + + +V++++ E
Sbjct: 1316 GLKEAVEI-FLAEGVNICTNDYKYSTPLHLACLYGHKEVVQILLREKANIDASNNNSLTPLHFACQNGHKELVEILIRENANIDSEAQNKITPLHLACEKGHKEVVEIFIREKANIEALAENKFTPLHLACVNGHKEVVEILIKEKANIDALTHKNFTPLHWTCRNGHKEVVKILIRGKASIDALAENKFTPLHFACENGHKEVIEILIKE 1525 HSP 7 Score: 147.517 bits (371), Expect = 2.172e-33 Identity = 68/170 (40.00%), Postives = 103/170 (60.59%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIA 697
P+H AC NGH+EVV+ LI A I++ + + P+ FAC N HK+++ LI+ + I+AL + P+HWACR GH EIV++L++ +I+A H + P+H +CR GH +VK L+ NI+A P+HWAC G+ EV +LI K +D +N T ++ A
Sbjct: 1539 PLHWACRNGHKEVVEILIRGKANIDALAEKKFTPLHFACRNGHKEIVKKLIRKKANIDALTHENFTPLHWACRNGHREIVEILVRKNSNIDALTHRNFTPLHWACRNGHKEVVKTLLREKANIDALTHKNSTPLHWACRNGHKEVVEILIKEKANIDASAENKFTSLHKA 1708 HSP 8 Score: 137.887 bits (346), Expect = 3.563e-30 Identity = 67/228 (29.39%), Postives = 123/228 (53.95%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACR---------------------------------FGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
+N +D N P+H AC+NGH+++ + L+ K A I++ + P+ AC N HK + IL++ + +I ALD +W+P+H AC +GH E+V++L++ + +I+A ++ L P+H +C+ GH +V++LI N NI++ +K P+H AC G+ EV + I K ++ L +N TP+++A + +V++++ E
Sbjct: 1232 VNAVDTNKCTPLHFACQNGHKKIAEILLRKKANIDALNGWNCTPLLLACQNGHKKIAEILLREKAKIAALDHMRWRPLHLACMSGLKEAVEIFLAEGVNICTNDYKYSTPLHLACLYGHKEVVQILLREKANIDASNNNSLTPLHFACQNGHKELVEILIRENANIDSEAQNKITPLHLACEKGHKEVVEIFIREKANIEALAENKFTPLHLACVNGHKEVVEILIKE 1459 HSP 9 Score: 105.531 bits (262), Expect = 9.816e-20 Identity = 53/181 (29.28%), Postives = 98/181 (54.14%), Query Frame = 2
Query: 191 IHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
+H++ G+ VV+ L+ GA + + P+ FAC N HK + IL++ + I+AL+ P+ AC+ GH +I ++L++ + I A H RP+H++C G V++ + NI D P+H AC G+ EV ++L+ K +D N+ TP++ A Q + ++++++
Sbjct: 1210 LHLSSSKGYCLVVELLLSNGANVNAVDTNKCTPLHFACQNGHKKIAEILLRKKANIDALNGWNCTPLLLACQNGHKKIAEILLREKAKIAALDHMRWRPLHLACMSGLKEAVEIFLAEGVNICTNDYKYSTPLHLACLYGHKEVVQILLREKANIDASNNNSLTPLHFACQNGHKELVEIL 1390 HSP 10 Score: 94.7449 bits (234), Expect = 2.250e-16 Identity = 50/172 (29.07%), Postives = 93/172 (54.07%), Query Frame = 2
Query: 236 LIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLIT---NKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
LI+ GA + + G + + + V+ +L+ N +NA+D NK P+H+AC+ GH +I ++L++ + +I+A + P+ ++C+ GH I ++L+ I A D +WRP+H AC G E + + N CT D TP+++A Y + +V++++ E
Sbjct: 1192 LINDGANVNAPNSTGCTVLHLSSSKGYCLVVELLLSNGANVNAVDTNKCTPLHFACQNGHKKIAEILLRKKANIDALNGWNCTPLLLACQNGHKKIAEILLREKAKIAALDHMRWRPLHLACMSGLKEAVEIFLAEGVNICTNDY---KYSTPLHLACLYGHKEVVQILLRE 1360 HSP 11 Score: 74.7146 bits (182), Expect = 4.689e-10 Identity = 55/217 (25.35%), Postives = 97/217 (44.70%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRF-GHWEIVKLLIKNRCDIEACG-------------------------------HDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
+H+AC +G ++ + LI K A+ + G P+ A H +V++ILI+N E L K + W GH + K+LI+ + A G +H+S G+ +V+LL+ N N+ A D++K P+H+AC G+ ++A +L+ K +D L N TP+ +A Q + + +++ E
Sbjct: 1079 ALHIACNSGDADMTRMLIQKCARDDVTTNKGKTPLDLAAAGGHTEVVIILIENMIETFLLSW-KTDDVLWNVVINGHDSLKKMLIREYIKLPALGCFVDLDILAWEGIIKKLERLINDGANVNAPNSTGCTVLHLSSSKGYCLVVELLLSNGANVNAVDTNKCTPLHFACQNGHKKIAEILLRKKANIDALNGWNCTPLLLACQNGHKKIAEILLRE 1294 HSP 12 Score: 72.4034 bits (176), Expect = 2.604e-9 Identity = 38/125 (30.40%), Postives = 63/125 (50.40%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLR------PIHISCRYGHTNIVKLLIEN 544
P+H A GH +V+ L+ KGA I GW + +A N + +LI ++N++ + KW +H AC G ++ ++LI + C DD+ P+ ++ GHT +V +LIEN
Sbjct: 1013 PLHSAIIYGHINLVQLLLRKGADIHCRNTEGWSALHYAVHNKQITITKLLIDKGTDVNSITKKKWNALHIACNSGDADMTRMLI------QKCARDDVTTNKGKTPLDLAAAGGHTEVVIILIEN 1131 HSP 13 Score: 68.5514 bits (166), Expect = 4.048e-8 Identity = 36/117 (30.77%), Postives = 63/117 (53.85%), Query Frame = 2
Query: 386 PIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKN-NKTPINIAEQYRYTDVMKVI 733
P+H A +GH +V+LL++ DI + +H + I KLLI+ ++ + KW +H AC G+ ++ R+LI KC D +T N KTP+++A +T+V+ ++
Sbjct: 1013 PLHSAIIYGHINLVQLLLRKGADIHCRNTEGWSALHYAVHNKQITITKLLIDKGTDVNSITKKKWNALHIACNSGDADMTRMLI-QKCARDDVTTNKGKTPLDLAAAGGHTEVVIIL 1128
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000008518.2 (pep primary_assembly:Astyanax_mexicanus-2.0:19:14507502:14520436:1 gene:ENSAMXG00000008289.2 transcript:ENSAMXT00000008518.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 132.109 bits (331), Expect = 2.199e-33 Identity = 88/262 (33.59%), Postives = 138/262 (52.67%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSS---RRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
F K IG+GSFG+V +K + + + VV I+ +++ +I + I +L+ + YYG K K +I+MEY+ GS L+ +E + QI + ++I++G+E+LH + IHRDI +N+LL ++KL DFG + + DT + TF GT ++APE+I Y ADIWS+G T + G E +++ I KN P L + + V+ LN +PS RPTA LLKH+L +
Sbjct: 21 FTKLEKIGKGSFGEV--FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLLEPG-PLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKR--NTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKN-----NPPTLEGNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIV 272
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140]) HSP 1 Score: 129.028 bits (323), Expect = 2.489e-33 Identity = 83/272 (30.51%), Postives = 137/272 (50.37%), Query Frame = 2
Query: 827 CSND---FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIE---NNINRYIDLL---NHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFG----FSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGR-ELFHEKSICEIVTFILKNKKIDFKPL--ELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
C +D +AKG +GRG++G V L G VK ++ S E + + R +DLL H IV + G I MEY+P GS+ + + + + K ++Q++EGV +LH N++IHRD+ +N++L +KL DFG +R+ + K+ GT ++APE+I++ + +D+WS+G T+F M G+ L H + + F + +K PL + S S + ++N K RP+AA LL+H
Sbjct: 9 CKDDTITWAKGEVLGRGAYGTVYC-GLTSQGQLIAVKQVLLDVSTSETAEKEYSRLEREVDLLKNLEHPNIVGFLGTALTDNVISIFMEYVPGGSISSVLNRFGPLPEKVFALYTRQVLEGVAYLHENRVIHRDLKGNNLMLMPTGVVKLIDFGCARRLNRLTHSGGNSDLLKSVHGTPYWMAPEVINETGHGKKSDVWSIGCTVFEMATGKPPLAHMGKMAAL--FYIGARKGLMPPLPDDFSEEAKSFVKACLINQK--QRPSAADLLRH 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: stk24b (serine/threonine-protein kinase 24-like [Source:NCBI gene;Acc:103028447]) HSP 1 Score: 132.494 bits (332), Expect = 2.733e-33 Identity = 90/272 (33.09%), Postives = 143/272 (52.57%), Query Frame = 2
Query: 809 QDIYSKCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELS---SRRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
Q++ + F K IG+GSFG+V +K + + + VV I+ +++ +I + I +L+ + YYG K K +I+MEY+ GS L+ +E ++ QI + ++I++G+E+LH + IHRDI +N+LL +KL DFG + + D TQ TF GT ++APE+I Y ADIWS+G T + G + +++ I KN P L S+ + V+ LN +PS RPTA LLKH+L +
Sbjct: 14 QNLKADPEQLFTKLERIGKGSFGEV--FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLLEPG-ALDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTD--TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKN-----NPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKLIV 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:103026704]) HSP 1 Score: 134.42 bits (337), Expect = 4.655e-33 Identity = 86/257 (33.46%), Postives = 129/257 (50.19%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIE--NNINRYIDLLN---HERIVSYYGVVQKA--KKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-KTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
G+ +G+G+FG+V L +G E VK + D + + + I LL HERIV YYG ++ + I MEYMP GS+ + ++ ++ ++QI+EGV +LH N I+HRDI +NIL D+ N+KL DFG SR ++ K+ GT +++PE+IS + Y ADIWSVG T+ ML R + E + I P +S + + + K RP A LL+H
Sbjct: 362 GKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVSALECEIQLLKNLFHERIVQYYGCLRDTHERTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICLSGTGIKSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTLRPPWAEFEAMAAIFKIATQPTNPALPAHVSDHCRDFLKRIFVETK--QRPAAEELLRH 616
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: stk24b (serine/threonine-protein kinase 24-like [Source:NCBI gene;Acc:103028447]) HSP 1 Score: 130.568 bits (327), Expect = 1.100e-32 Identity = 86/256 (33.59%), Postives = 137/256 (53.52%), Query Frame = 2
Query: 857 IGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELS---SRRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
IG+GSFG+V +K + + + VV I+ +++ +I + I +L+ + YYG K K +I+MEY+ GS L+ +E ++ QI + ++I++G+E+LH + IHRDI +N+LL +KL DFG + + DT + TF GT ++APE+I Y ADIWS+G T + G + +++ I KN P L S+ + V+ LN +PS RPTA LLKH+L +
Sbjct: 3 IGKGSFGEV--FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLLEPG-ALDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKR--NTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKN-----NPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKLIV 248
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 144.05 bits (362), Expect = 5.277e-37 Identity = 89/267 (33.33%), Postives = 144/267 (53.93%), Query Frame = 2
Query: 824 KCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIET---DDSRMIENNINRYIDLL---NHERIVSYYGVVQ--KAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-KTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFK-PLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
+ ++ +G+ +G+G+FG+V L +G E VK + + S+ + N + I LL HERIV Y+G ++ + K I MEYMP GS+ + + ++ ++QI+EGV FLHGN I+HRDI +NIL D+ N+KL DFG S+ ++ +Q A ++ GT +++PE+I+ + Y ADIWSVG T+ ML + + E + F + + D + PL S + + + K RP+A LL+H
Sbjct: 354 RAPTNWQRGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPGSVETSKEV-NALECEIQLLKNLQHERIVQYFGCLRDPQQKTLSIFMEYMPGGSIKDQLRAYGALTENVTRKYTRQILEGVSFLHGNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICSQGTAMRSVTGTPYWMSPEVINGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAI-FKIATQPTDPRLPLHASEHARDLLRRIFVEAK--LRPSAEDLLRH 616
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 124.02 bits (310), Expect = 6.799e-31 Identity = 87/262 (33.21%), Postives = 133/262 (50.76%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDI--TPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELS---SRRMSTIVKEMLNYKPSNRPTAASLLKHEL 1600
F K IG+GSFG+V +K + + + VV I+ +++ +I + I +L+ + Y+G K K +I+MEY+ GS L+ I K + QI + ++I++G+++LH + IHRDI +N+LL ++KL DFG + + DT + TF GT ++APE+I Y F ADIWS+G T + G E ++ I KN P L S+ V LN P RPTA LLKH+
Sbjct: 26 FTKQERIGKGSFGEV--FKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTHYFGSYLKGTKLWIIMEYLGGGSALDLI-KPGPLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDTQIKR--NTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKN-----NPPTLEGNYSKAFKEFVDSCLNKDPQFRPTAKELLKHKF 277
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: MARK3 (microtubule affinity regulating kinase 3 [Source:HGNC Symbol;Acc:HGNC:6897]) HSP 1 Score: 121.324 bits (303), Expect = 5.784e-30 Identity = 68/214 (31.78%), Postives = 115/214 (53.74%), Query Frame = 2
Query: 851 RCIGRGSFGKVILYKLLKSGHEFVVK---STYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFP-ADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNK 1480
+ IG+G+F KV L K +G E VK T + T + + + R + +LNH IV + V++ K Y++MEY G + + + + K+ +QI+ V++ H I+HRD+ N+LLDA+ NIK+ DFGFS + + TFCG+ Y APE+ ++Y P D+WS+G ++ ++ G F +++ E+ +L+ K
Sbjct: 72 KTIGKGNFAKVKLAKHTLTGQEVAVKIIDKTQLNTSSLQKLFREV-RIMKVLNHPNIVKLFEVIEMEKTLYLVMEYSSGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIVHRDLKAENLLLDADMNIKIADFGFS---NEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGK 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 120.168 bits (300), Expect = 1.302e-29 Identity = 77/257 (29.96%), Postives = 127/257 (49.42%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVK----STYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLEL---SSRRMSTIVKEMLNYKPSNRPTAAS 1582
+DF +G+GSFGKV+L K G + VK S ++ + + I N + + H +V + Q A K Y +M+Y+ G L +++ S + + +I + +LH I++RD+ P NILLD +I LTDFG + D + C TFCGT YLAPE++ Y D W +G ++ ML G F+ K++ ++ IL +PL+L ++ ++++ +L+ P R A S
Sbjct: 90 SDFDFLTVLGKGSFGKVLLAKHKSDGIFYAVKVMKKSIILQKKEEKHIMAERNVLVKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTC--TFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILH------QPLQLRPCTTNAAISVLEGLLHKDPHQRLGATS 338
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: pdpk1b (3-phosphoinositide dependent protein kinase 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1820]) HSP 1 Score: 120.939 bits (302), Expect = 1.405e-29 Identity = 72/251 (28.69%), Postives = 125/251 (49.80%), Query Frame = 2
Query: 824 KCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVK---STYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNR 1567
K DF G+ +G GSF V+L K + +G E+ +K +I + N + LNH V + Q +K Y + Y G +L I K S S QI+ +E LH IIHRD+ P NILL+ + +I++TDFG ++++ D + A +F GT Y++PE+++++ +D+W++G I+ ++ G F + I I+ K++++ E + +V+++L P R
Sbjct: 19 KRPEDFKFGKILGEGSFSTVVLAKEVATGKEYAIKILEKRHIIKEKKVPYVNREKEVLSRLNHPFFVKLFFTFQDEEKLYFGLSYAKNGEMLKYIRKHRSFDENCTRFYSAQIVSSLEHLHSLGIIHRDLKPENILLNEDMHIQITDFGTAKILSDNSKHARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAPNEYLIFQKII---KLEYEFPEKFFPKAKDLVEKLLVSDPMQR 266
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]) HSP 1 Score: 131.724 bits (330), Expect = 3.141e-34 Identity = 75/228 (32.89%), Postives = 124/228 (54.39%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEF---------VVKSTYIE-TDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKI 1486
+DF R +G GSFG+V L + + +G + VVK +E T+D R R + L+ H ++ +G Q A+ +++M+Y+ G L + + K+ + ++I +E+LH + II+RD+ P NILLD N +IK+TDFGF++ V Q T CGT +Y+APE+I+ + Y+ D WS+G I+ ML G F++ + + IL+ K +
Sbjct: 68 HDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDER-------RMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEV-----QTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVV 283
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: KCC4 (Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529]) HSP 1 Score: 133.65 bits (335), Expect = 2.732e-33 Identity = 88/266 (33.08%), Postives = 140/266 (52.63%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVK--STYI------ETDDSRMIENNINRYI---DLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQY-SFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFK-PLELS-SRRMSTIVKEMLNYKPSNRPTAASLLKHELF 1603
G +G GS GKV L + ++GH VK S I ++D ++ NI R I LL+H ++S Y V + Y+++EY +G L N + + ++ IN +QII G+ + H I+HRD+ P N+LLD+ +NIK+ DFG + + D + +T CG+ +Y APEI+S Y F +D+WS G +F +L GR F E++ + +LK +K F+ P + SR ++ ++L P R +L H L
Sbjct: 24 GETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDA---DLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEEN-GNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLL 285
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]) HSP 1 Score: 132.88 bits (333), Expect = 4.445e-33 Identity = 92/257 (35.80%), Postives = 138/257 (53.70%), Query Frame = 2
Query: 851 RCIGRGSFGKVILYKLLKSGHEFVV--KSTYIETDDSRMIENNINRYIDLL---NHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSK----QIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
+ IGRGS+G ++YK + + VV K E D+ N+I I LL NH IV Y+G ++K+ + YIL+EY GSL I ++ + L + N SK Q + G+++LHG +IHRDI +NILL A+ +KL DFG S +V +A T GT+N++APEI+ ++ S +DIWS+GAT+ ML +H + I + ++N + P S + + + RPTA LLKH
Sbjct: 29 QVIGRGSYG--VVYKAINKHTDQVVAIKEVVYENDEEL---NDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSE---NESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSAL-----TLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIY-YAVENDT--YYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKH 269
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 127.872 bits (320), Expect = 1.000e-32 Identity = 75/233 (32.19%), Postives = 123/233 (52.79%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGH---------EFVVKSTYIE-TDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPL 1501
DF R +G GSFG+V L + +G E VV+ +E T+D R++ + ++ H I+ +G Q A++ +++M+Y+ G L + + K+ + ++ +E+LH II+RD+ P NILLD N +IK+TDFGF++ V D T CGT +Y+APE++S + Y+ D WS G I+ ML G F++ + + IL N ++ F P
Sbjct: 85 QDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLM-------LSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD-----VTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKIL-NAELRFPPF 304
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 127.872 bits (320), Expect = 1.109e-32 Identity = 72/226 (31.86%), Postives = 123/226 (54.42%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIET-DDSRMIE--NNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPL 1501
+DF R +G GSFG+V L + +G + +K+ T + +E N+ R + +++H I+ +G Q +++ +++M+Y+ G L + + K+ + ++ +E+LH II+RD+ P NILLD N +IK+TDFGF++ V D T CGT +Y+APE++S + Y+ D WS G I+ ML G F+ + + IL N ++ F P
Sbjct: 86 SDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD-----VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENIL-NAELKFPPF 305
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7]) HSP 1 Score: 140.584 bits (353), Expect = 6.101e-38 Identity = 85/261 (32.57%), Postives = 139/261 (53.26%), Query Frame = 2
Query: 833 NDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIET--------DDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLK 1591
N++ KG+ +G G+FG+V + L +G E VK IET ++ + +E I ++ +ERIV YYG+ YI MEY+P GS+ I++ ++ S+QI+EG+ +LH N+I+HRDI +NIL D N+KL DFG S+ ++ ++ ++ GT ++APE+I+ + Y AD+WSVG T+ ML + + + + I P +LS + V+ L +RP+A LL+
Sbjct: 2 NNWRKGKLLGAGAFGQVYMCHDLDTGRELAVKQ--IETGQLNSSTKNEVKALEGEIE-FMKAFRNERIVQYYGIETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYGNVKLADFGASKRLQTIRSKTGFRSVHGTPYWMAPEVINGEGYGRKADVWSVGCTVVEMLTTKPPWADFEPMAALFKIATQPTEPELPSDLSVDAVE-FVRSTLRMNSKSRPSADELLR 258
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG02]) HSP 1 Score: 129.798 bits (325), Expect = 6.488e-34 Identity = 84/266 (31.58%), Postives = 140/266 (52.63%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDD--SRMIENNINRYIDLLNHERIVSYYGVVQKAKKF-YILMEYMPQGSLLNCI--EKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHE-------LFLE 1609
G+CIG+GS+G+V L K K ++V+K ++ R + + L H IVSY Q F YI M + G L + + +K + + QI+ QI ++++H I+HRD+ NI L + IK+ D G +RV++ ++ + A T GT Y++PE+ S++ Y+ +D+W++G ++ M R F+ K + +V ILK K P + S+ + +I+K ML+ P RP+A+ LL+H LFLE
Sbjct: 9 GKCIGKGSYGEVFLSKHKKDKKQYVLKKVDLQKASVRERKAAELEAKLLSQLRHPNIVSYRESFQDDTGFLYIAMNFCEGGDLYSRLKAQKGIPLDENQIVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKSKIIKVGDLGIARVLESSS--DMATTLIGTPYYMSPELFSNKPYNHKSDVWALGCCLYEMCTLRHAFNAKDMSSLVYKILKGKTPPL-PKQYST-DLCSIIKSMLDQDPDKRPSASRLLRHPYIKKQIALFLE 270
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO48026 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKQ3]) HSP 1 Score: 126.716 bits (317), Expect = 1.411e-32 Identity = 73/222 (32.88%), Postives = 118/222 (53.15%), Query Frame = 2
Query: 824 KCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVK---STYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVV-KDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKN 1477
K ++DF G+ +G GS+ V + + + +G E+ +K +I+ + + + LNH V Y Q K Y + Y +G LL I + S K S +II +E LHG QIIHRD+ P NILLD N +IK+TDFG ++++ KD +F GT Y++PE+++D++ +DIW++G I+ +L G + + +I I+KN
Sbjct: 4 KKTSDFRFGKLLGEGSYSTVYVAQEISTGKEYAIKVLEKRHIQKEKKVAQVSREKEVLSRLNHPFFVILYFTFQDRDKLYFGLSYAKKGELLPYITRLGSFDEKCTQFYSAEIISALEHLHGLQIIHRDLKPENILLDENMHIKITDFGTAKILNKDEEKNKGRNSFVGTAQYVSPELLTDKRACKSSDIWALGCIIYQLLSGLTPYRAGNEYQIFQKIIKN 225
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO40703 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6E0]) HSP 1 Score: 125.946 bits (315), Expect = 1.839e-32 Identity = 78/259 (30.12%), Postives = 132/259 (50.97%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDS---RMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILL-----DANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKP--LELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
G+ +GRGSFG V K +++G + +K+ E S +++E + + + HE ++ + + +K+ Y++ME G L +E+ K+ V KQ++ V +LH I+HRD+ NILL + N+K+TDFG S V + + ++ CGT Y+APE+I D YS D+WS+G ++ + GR F + E + I+K +DF E+ ++ ML P++R TA +L H
Sbjct: 30 GQVLGRGSFGVVNEAKHIETGTRWAIKAVNKEKAGSSAVKLLEREV-MIMKKIYHEHLIHLEEIYETSKRMYLVMELCDAGGLDKMLERKKRFTEKETWTVIKQLVSAVAYLHDLDIVHRDLKLENILLSHPTGNELLNVKITDFGLSIVKGGVGSDSMMQSVCGTPMYMAPEVIDDLGYSQQCDVWSIGVIMYTLFTGRPPFMADT-EEKLYEIIKKGIVDFSDPCWEVCHESAKNLLLGMLKVDPAHRRTAKEVLIH 286
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO36169 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJE6]) HSP 1 Score: 129.798 bits (325), Expect = 3.284e-32 Identity = 86/247 (34.82%), Postives = 123/247 (49.80%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYID---LLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFP-ADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFK-PLELSSRRMSTIVKEMLNYKPSNRPT 1573
G +G G+FGKV L +GH+ +K S + I R I L H I+ Y V+ +++MEY+ G L I K + K +QII GV++ H + ++HRD+ P N+LLD+ NIK+ DFG S ++ D +T CG+ NY APE+IS + Y+ P DIWS G ++ +L G F ++ I T K K F P LSS S ++ MLN P R T
Sbjct: 23 GETLGVGTFGKVKLAVHQLTGHKVAIKILNRNKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPTDIFMVMEYVSGGELFEYILKHGKLEEKDARRFFQQIISGVDYCHRHMVVHRDLKPENLLLDSQLNIKIADFGLSNIMTDG---EFLQTSCGSPNYAAPEVISGKLYAGPEVDIWSAGVILYALLCGTLPFDDE---HIPTLFRKIKGGVFHVPPHLSSGPAS-LLNAMLNVDPIKRAT 262
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: prkaa2 (protein kinase AMP-activated catalytic subunit alpha 2 [Source:NCBI gene;Acc:101173851]) HSP 1 Score: 132.494 bits (332), Expect = 1.306e-32 Identity = 82/256 (32.03%), Postives = 132/256 (51.56%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYID---LLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFP-ADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELF 1603
G +G G+FGKV + + +GH+ VK + S + I R I L H I+ Y V+ F+++MEY+ G L + I K + + + +QII V++ H + ++HRD+ P N+LLDAN N K+ DFG S ++ D +T CG+ NY APE+IS + Y+ P DIWS G ++ +L G F ++ + T K + F E +R +++++ ML P R T + +H+ F
Sbjct: 21 GDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQRIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKNGRVEDPEARRLFQQIISAVDYCHRHMVVHRDLKPENVLLDANKNAKIADFGLSNMMSDG---EFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDE---HVPTLFKKIRGGVFYMPEYLTRSVASLLMLMLQVDPLKRATIKDIREHDWF 270
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: stk24b (serine/threonine kinase 24 [Source:NCBI gene;Acc:101160144]) HSP 1 Score: 129.413 bits (324), Expect = 3.308e-32 Identity = 87/262 (33.21%), Postives = 137/262 (52.29%), Query Frame = 2
Query: 839 FAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNH---ERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSS---RRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
F K IG+GSFG+V +K + + + VV I+ +++ +I + I +L+ + YYG K K +I+MEY+ GS L+ +E + QI + ++I++G+E+LH + IHRDI +N+LL +KL DFG + + DT + TF GT ++APE+I Y ADIWS+G T + G + +++ I KN P L + + V+ LN +PS RPTA LLKH+L +
Sbjct: 24 FTKLERIGKGSFGEV--FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLMEPG-PLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKR--NTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKN-----NPPTLEGSYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIV 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:101160297]) HSP 1 Score: 132.109 bits (331), Expect = 3.846e-32 Identity = 85/257 (33.07%), Postives = 132/257 (51.36%), Query Frame = 2
Query: 848 GRCIGRGSFGKVILYKLLKSGHEFVVKSTYI--ETDDSRMIENNINRYIDLLN---HERIVSYYGVVQKA--KKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-KTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKH 1594
G+ +G+G+FG+V L +G E VK E+ ++ + + I LL HERIV YYG ++ + I ME+MP GS+ + ++ ++ ++QI+EGV +LH N I+HRDI +NIL D+ N+KL DFG SR ++ K+ GT +++PE+IS + Y ADIWSVG T+ ML R + E + I P+ +S + + + K RP+A LL+H
Sbjct: 392 GKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPESPETSKEVSALECEIQLLKNLCHERIVQYYGCLRDTMERTLSIFMEHMPGGSIKDQLKSYGALTENVTRRYTRQILEGVSYLHSNMIVHRDIKGANILRDSVGNVKLGDFGASRRLQTICLSGTGIKSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPELPVHVSDHCREFLRRIFVETK--QRPSADELLRH 646
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:101169290]) HSP 1 Score: 131.339 bits (329), Expect = 4.970e-32 Identity = 83/262 (31.68%), Postives = 136/262 (51.91%), Query Frame = 2
Query: 845 KGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRM------IENNINRYIDLLNHERIVSYYGVVQ--KAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-KTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLN---YKPSNRPTAASLLKH 1594
+G+ +G+G+FG V L + +G E K + D +E I + + L+HERIV YYG ++ K I MEYMP GS+ + ++ ++ ++QI+EG+ +LH N I+HRDI +NIL D+ N+KL DFG S+ ++ ++ GT +++PE+IS + Y AD+WS+G T+ ML + + E E + I K PL S S ++ ++ + +RP+A LL+H
Sbjct: 355 RGKLLGQGAFGLVYLCYDVDTGRELAAKQVQFDPDSPETSKEVSALECEI-QLLKNLHHERIVQYYGCLRDHSEKTLTIFMEYMPGGSVKDQLKAYGALTENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE---YEAMAAIFKIATQPTNPLLPS--HTSDQARDFIHCIFVEAKHRPSAEELLRH 610
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:NCBI gene;Acc:101156777]) HSP 1 Score: 132.88 bits (333), Expect = 5.066e-32 Identity = 92/293 (31.40%), Postives = 142/293 (48.46%), Query Frame = 2
Query: 740 ELKRQLFDRISRAFQVSNDFNLDQDIYSKCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMI-----ENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQ-IINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNI-KLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEII--SDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLK 1591
++K + D A ++ + + D Y +N+ +GRG++G V + L + +K I DSR E +++Y L H IV Y G + + I ME +P GSL + L++ II ++QI+EG+ +LH NQI+HRDI N+L++ + K++DFG S+ + C +TF GT+ Y+APEII + Y PADIWS+G TI M G+ FHE + F + KI + E S + + P+ RP LLK
Sbjct: 585 KVKEMISDSTGNAVELEGEGDGDTLEYEYDTNETGDRVVLGRGTYGVVYAGRDLSNQVRIAIKE--IPERDSRYSQPLHEEIALHKY---LKHRNIVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKEATIIFYTRQILEGLRYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRL--AGVNPCTETFTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGKPPFHELGEPQAAMFKVGMFKIHPEIPESLSLEAKSFILRCFEPDPNKRPITTDLLK 870
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000022974.1 (SMESG000022974.1) HSP 1 Score: 1052.35 bits (2720), Expect = 0.000e+0 Identity = 509/513 (99.22%), Postives = 509/513 (99.22%), Query Frame = 2
Query: 98 MSKVKLGIIDEVKISFMPEYLNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDRISRAFQVSNDFNLDQDIYSKCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFLELDYSISSFK 1636
MSKVKLGIIDEVKISFMPEYLNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARD SKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDRISRAFQVSNDFNLDQDIYSKCSNDFAK RCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDAN NIKLTDFGFSRVVKDT TQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFLELDYSISSFK
Sbjct: 1 MSKVKLGIIDEVKISFMPEYLNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDYSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDRISRAFQVSNDFNLDQDIYSKCSNDFAKVRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANLNIKLTDFGFSRVVKDTGTQNCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFLELDYSISSFK 513
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000026756.1 (SMESG000026756.1) HSP 1 Score: 380.948 bits (977), Expect = 7.720e-123 Identity = 199/491 (40.53%), Postives = 299/491 (60.90%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDRIS-----RAFQVSNDFNLDQDIYSKCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNC---AKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
L+ + PIH A GH+E+VK L+ + IE K R I +AC H +++ +L+ CEINA D+N +PIH AC+ GH EIVKLL+ +CD E + L PIH +C YG+ +++ +L+ NN +E D RPIH+AC+ G++ + ++LI+ C ++ TK N +P+++A Q ++ +++++ D L+R++ D + + F + + + SK F +G IG GSFG+ YKL ++ E V+K T I++ +S+ IE NIN+Y+ ++ H IV Y+G ++ K YI MEY+ GSL + I+K SI ++II SKQI++G+ FLH +IIHRDI P NIL++ IKL+DFG S+ +K T ++ AKTFCGT NY+APEI++++ Y FPADIWS GATI ML G FH + ++ I KKI+F P E S + + +ML P R +AASLL H LFL
Sbjct: 322 LDAESLTGSRPIHFASFYGHDEIVKILLSERCNIELQDKDSGRAIHYACCRGHLNIVEMLLAQSCEINAGDKNYRRPIHHACQNGHCEIVKLLVSYKCDKEVRDENKLTPIHYACFYGYFDVMTVLLINNFKVEVGDKDDGRPIHYACFFGHLHIVKILISQNCNIEACTKENWSPLDLASQKGFSQIVELLSDTLRRKIIDSLVEELGIQCFDGCSHYLCKSSLESK---QFQEGEFIGSGSFGRAFKYKLPQNNKEIVIKYTEIDS-ESKYIERNINKYVKIIRHINIVQYFGALEVCGKLYIYMEYLSGGSLEDQIKKLGSIAHEKIIFYSKQILQGLAFLHSKKIIHRDIKPGNILMNEEELIKLSDFGLSKSLKITTARDTIENAKTFCGTPNYIAPEIVNEEPYDFPADIWSTGATITEMLTGLAPFHGMNQFAVIYKIGNTKKIEFTPREPVSEQFQIFIDQMLKPNPKERASAASLLSHRLFL 808 HSP 2 Score: 159.844 bits (403), Expect = 2.490e-41 Identity = 81/208 (38.94%), Postives = 126/208 (60.58%), Query Frame = 2
Query: 119 IIDEVKISFMPEYLNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
+ID +I E L+K DM P+H A +NGH V++ L+ + + + + K PI +A N H D + +L+K+ I A D+ PIH+AC+ GH +V+LLI C IE C D +PIH +C+ H IVKLL+++ CN+EA D + RPIH+AC+ GNVE+ +LLI+++C LD + PI+ A Y + +++K++ E
Sbjct: 151 LIDRCQI----ESLDKHDM---MPLHYASQNGHCGVLELLLSRVSNVNAVDKRSQSPIHYAAQNGHVDAVSLLLKHNSAIEAPDKFDRCPIHYACQNGHLNVVRLLISEGCSIEICDKDKRKPIHFACQNDHVEIVKLLLKSKCNLEASDKNGLRPIHYACFHGNVEIVKLLISSQCCLDAESLTGSRPIHFASFYGHDEIVKILLSE 351 HSP 3 Score: 155.606 bits (392), Expect = 6.619e-40 Identity = 75/182 (41.21%), Postives = 115/182 (63.19%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
PIH AC+NGH VV+ LI +G IE K +PI FAC N H +++ +L+K++C + A D+N +PIH+AC G+ EIVKLLI ++C ++A RPIH + YGH IVK+L+ CNIE +D R IH+AC G++ + +L+ C ++ KN + PI+ A Q + +++K++
Sbjct: 233 PIHYACQNGHLNVVRLLISEGCSIEICDKDKRKPIHFACQNDHVEIVKLLLKSKCNLEASDKNGLRPIHYACFHGNVEIVKLLISSQCCLDAESLTGSRPIHFASFYGHDEIVKILLSERCNIELQDKDSGRAIHYACCRGHLNIVEMLLAQSCEINAGDKNYRRPIHHACQNGHCEIVKLL 414 HSP 4 Score: 151.754 bits (382), Expect = 1.140e-38 Identity = 71/180 (39.44%), Postives = 115/180 (63.89%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIA 697
+N +D PIH A +NGH + V L+ + IE+ KF PI +AC N H +V+ +LI C I D++K +PIH+AC+ H EIVKLL+K++C++EA + LRPIH +C +G+ IVKLLI + C ++A + RPIH+A + G+ E+ ++L++ +C +++ K++ I+ A
Sbjct: 190 VNAVDKRSQSPIHYAAQNGHVDAVSLLLKHNSAIEAPDKFDRCPIHYACQNGHLNVVRLLISEGCSIEICDKDKRKPIHFACQNDHVEIVKLLLKSKCNLEASDKNGLRPIHYACFHGNVEIVKLLISSQCCLDAESLTGSRPIHFASFYGHDEIVKILLSERCNIELQDKDSGRAIHYA 369 HSP 5 Score: 140.969 bits (354), Expect = 5.300e-35 Identity = 68/182 (37.36%), Postives = 114/182 (62.64%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
PIH AC+ G ++VK L+ +E K RPI +AC + D++ +L+ +C I D N +PIH+AC+ G+ +IV+LL+ N+ D EA ++ RP+H +CR GH N+V+LL+ C+IE D S RPIH+AC G+ ++ +LI ++C ++ L K++ P++ A Q + V++++
Sbjct: 3 PIHYACQYGQLDLVKMLLMGMCDVEVFCKNDKRPIHYACESGDYDIVKLLLSYKCNIEVCDINLMRPIHYACQNGYHKIVELLLSNQADKEAKDKNNGRPLHHACRSGHANVVELLLNYYCDIEVHDKSNLRPIHYACLSGSYQIVEMLI-DRCQIESLDKHDMMPLHYASQNGHCGVLELL 183 HSP 6 Score: 134.806 bits (338), Expect = 5.192e-33 Identity = 66/188 (35.11%), Postives = 113/188 (60.11%), Query Frame = 2
Query: 170 DMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
D N P+H AC +GH VV+ L++ IE H K RPI +AC + ++ +LI +RC+I +LD++ P+H+A + GH +++LL+ ++ A PIH + + GH + V LL+++N IEA D PIH+AC G++ V RLLI+ C++++ K+ + PI+ A Q + +++K++
Sbjct: 96 DKNNGRPLHHACRSGHANVVELLLNYYCDIEVHDKSNLRPIHYACLSGSYQIVEMLI-DRCQIESLDKHDMMPLHYASQNGHCGVLELLLSRVSNVNAVDKRSQSPIHYAAQNGHVDAVSLLLKHNSAIEAPDKFDRCPIHYACQNGHLNVVRLLISEGCSIEICDKDKRKPIHFACQNDHVEIVKLL 282 HSP 7 Score: 126.716 bits (317), Expect = 2.474e-30 Identity = 66/186 (35.48%), Postives = 106/186 (56.99%), Query Frame = 2
Query: 176 NFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
N PIH ACE+G ++VK L+ IE RPI +AC N + ++ +L+ N+ + A D+N +P+H ACR GH +V+LL+ CDIE +LRPIH +C G IV++LI+ C IE+ D P+H+A G+ V LL++ ++ + K +++PI+ A Q + D + ++
Sbjct: 32 NDKRPIHYACESGDYDIVKLLLSYKCNIEVCDINLMRPIHYACQNGYHKIVELLLSNQADKEAKDKNNGRPLHHACRSGHANVVELLLNYYCDIEVHDKSNLRPIHYACLSGSYQIVEMLID-RCQIESLDKHDMMPLHYASQNGHCGVLELLLSRVSNVNAVDKRSQSPIHYAAQNGHVDAVSLL 216 HSP 8 Score: 115.931 bits (289), Expect = 8.079e-27 Identity = 55/162 (33.95%), Postives = 96/162 (59.26%), Query Frame = 2
Query: 281 WRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDR 766
RPI +AC D++ +L+ C++ +N +PIH+AC G ++IVKLL+ +C+IE C + +RPIH +C+ G+ IV+LL+ N + EA+D + RP+H AC G+ V LL+ C +++ K+N PI+ A +++++ D + + D+
Sbjct: 1 MRPIHYACQYGQLDLVKMLLMGMCDVEVFCKNDKRPIHYACESGDYDIVKLLLSYKCNIEVCDINLMRPIHYACQNGYHKIVELLLSNQADKEAKDKNNGRPLHHACRSGHANVVELLLNYYCDIEVHDKSNLRPIHYACLSGSYQIVEMLIDRCQIESLDK 162
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000026756.1 (SMESG000026756.1) HSP 1 Score: 380.563 bits (976), Expect = 1.168e-122 Identity = 199/491 (40.53%), Postives = 299/491 (60.90%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDRIS-----RAFQVSNDFNLDQDIYSKCSNDFAKGRCIGRGSFGKVILYKLLKSGHEFVVKSTYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNC---AKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELFL 1606
L+ + PIH A GH+E+VK L+ + IE K R I +AC H +++ +L+ CEINA D+N +PIH AC+ GH EIVKLL+ +CD E + L PIH +C YG+ +++ +L+ NN +E D RPIH+AC+ G++ + ++LI+ C ++ TK N +P+++A Q ++ +++++ D L+R++ D + + F + + + SK F +G IG GSFG+ YKL ++ E V+K T I++ +S+ IE NIN+Y+ ++ H IV Y+G ++ K YI MEY+ GSL + I+K SI ++II SKQI++G+ FLH +IIHRDI P NIL++ IKL+DFG S+ +K T ++ AKTFCGT NY+APEI++++ Y FPADIWS GATI ML G FH + ++ I KKI+F P E S + + +ML P R +AASLL H LFL
Sbjct: 328 LDAESLTGSRPIHFASFYGHDEIVKILLSERCNIELQDKDSGRAIHYACCRGHLNIVEMLLAQSCEINAGDKNYRRPIHHACQNGHCEIVKLLVSYKCDKEVRDENKLTPIHYACFYGYFDVMTVLLINNFKVEVGDKDDGRPIHYACFFGHLHIVKILISQNCNIEACTKENWSPLDLASQKGFSQIVELLSDTLRRKIIDSLVEELGIQCFDGCSHYLCKSSLESK---QFQEGEFIGSGSFGRAFKYKLPQNNKEIVIKYTEIDS-ESKYIERNINKYVKIIRHINIVQYFGALEVCGKLYIYMEYLSGGSLEDQIKKLGSIAHEKIIFYSKQILQGLAFLHSKKIIHRDIKPGNILMNEEELIKLSDFGLSKSLKITTARDTIENAKTFCGTPNYIAPEIVNEEPYDFPADIWSTGATITEMLTGLAPFHGMNQFAVIYKIGNTKKIEFTPREPVSEQFQIFIDQMLKPNPKERASAASLLSHRLFL 814 HSP 2 Score: 159.844 bits (403), Expect = 2.902e-41 Identity = 81/208 (38.94%), Postives = 126/208 (60.58%), Query Frame = 2
Query: 119 IIDEVKISFMPEYLNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
+ID +I E L+K DM P+H A +NGH V++ L+ + + + + K PI +A N H D + +L+K+ I A D+ PIH+AC+ GH +V+LLI C IE C D +PIH +C+ H IVKLL+++ CN+EA D + RPIH+AC+ GNVE+ +LLI+++C LD + PI+ A Y + +++K++ E
Sbjct: 157 LIDRCQI----ESLDKHDM---MPLHYASQNGHCGVLELLLSRVSNVNAVDKRSQSPIHYAAQNGHVDAVSLLLKHNSAIEAPDKFDRCPIHYACQNGHLNVVRLLISEGCSIEICDKDKRKPIHFACQNDHVEIVKLLLKSKCNLEASDKNGLRPIHYACFHGNVEIVKLLISSQCCLDAESLTGSRPIHFASFYGHDEIVKILLSE 357 HSP 3 Score: 155.606 bits (392), Expect = 7.136e-40 Identity = 75/182 (41.21%), Postives = 115/182 (63.19%), Query Frame = 2
Query: 188 PIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
PIH AC+NGH VV+ LI +G IE K +PI FAC N H +++ +L+K++C + A D+N +PIH+AC G+ EIVKLLI ++C ++A RPIH + YGH IVK+L+ CNIE +D R IH+AC G++ + +L+ C ++ KN + PI+ A Q + +++K++
Sbjct: 239 PIHYACQNGHLNVVRLLISEGCSIEICDKDKRKPIHFACQNDHVEIVKLLLKSKCNLEASDKNGLRPIHYACFHGNVEIVKLLISSQCCLDAESLTGSRPIHFASFYGHDEIVKILLSERCNIELQDKDSGRAIHYACCRGHLNIVEMLLAQSCEINAGDKNYRRPIHHACQNGHCEIVKLL 420 HSP 4 Score: 151.754 bits (382), Expect = 1.272e-38 Identity = 71/180 (39.44%), Postives = 115/180 (63.89%), Query Frame = 2
Query: 158 LNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIA 697
+N +D PIH A +NGH + V L+ + IE+ KF PI +AC N H +V+ +LI C I D++K +PIH+AC+ H EIVKLL+K++C++EA + LRPIH +C +G+ IVKLLI + C ++A + RPIH+A + G+ E+ ++L++ +C +++ K++ I+ A
Sbjct: 196 VNAVDKRSQSPIHYAAQNGHVDAVSLLLKHNSAIEAPDKFDRCPIHYACQNGHLNVVRLLISEGCSIEICDKDKRKPIHFACQNDHVEIVKLLLKSKCNLEASDKNGLRPIHYACFHGNVEIVKLLISSQCCLDAESLTGSRPIHFASFYGHDEIVKILLSERCNIELQDKDSGRAIHYA 375 HSP 5 Score: 141.354 bits (355), Expect = 3.362e-35 Identity = 69/188 (36.70%), Postives = 116/188 (61.70%), Query Frame = 2
Query: 170 DMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
D + PIH AC+ G ++VK L+ +E K RPI +AC + D++ +L+ +C I D N +PIH+AC+ G+ +IV+LL+ N+ D EA ++ RP+H +CR GH N+V+LL+ C+IE D S RPIH+AC G+ ++ +LI ++C ++ L K++ P++ A Q + V++++
Sbjct: 3 DNDLMRPIHYACQYGQLDLVKMLLMGMCDVEVFCKNDKRPIHYACESGDYDIVKLLLSYKCNIEVCDINLMRPIHYACQNGYHKIVELLLSNQADKEAKDKNNGRPLHHACRSGHANVVELLLNYYCDIEVHDKSNLRPIHYACLSGSYQIVEMLI-DRCQIESLDKHDMMPLHYASQNGHCGVLELL 189 HSP 6 Score: 134.806 bits (338), Expect = 5.852e-33 Identity = 66/188 (35.11%), Postives = 113/188 (60.11%), Query Frame = 2
Query: 170 DMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVI 733
D N P+H AC +GH VV+ L++ IE H K RPI +AC + ++ +LI +RC+I +LD++ P+H+A + GH +++LL+ ++ A PIH + + GH + V LL+++N IEA D PIH+AC G++ V RLLI+ C++++ K+ + PI+ A Q + +++K++
Sbjct: 102 DKNNGRPLHHACRSGHANVVELLLNYYCDIEVHDKSNLRPIHYACLSGSYQIVEMLI-DRCQIESLDKHDMMPLHYASQNGHCGVLELLLSRVSNVNAVDKRSQSPIHYAAQNGHVDAVSLLLKHNSAIEAPDKFDRCPIHYACQNGHLNVVRLLISEGCSIEICDKDKRKPIHFACQNDHVEIVKLL 288 HSP 7 Score: 129.028 bits (323), Expect = 3.982e-31 Identity = 63/191 (32.98%), Postives = 113/191 (59.16%), Query Frame = 2
Query: 170 DMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE 742
D+N PIH AC+NG+ ++V+ L+ A E+ K RP+ AC + H +V+ +L+ C+I D++ +PIH+AC G ++IV++LI +RC IE+ D+ P+H + + GH +++LL+ N+ A D PIH+A G+V+ LL+ + ++ K ++ PI+ A Q + +V++++ E
Sbjct: 69 DINLMRPIHYACQNGYHKIVELLLSNQADKEAKDKNNGRPLHHACRSGHANVVELLLNYYCDIEVHDKSNLRPIHYACLSGSYQIVEMLI-DRCQIESLDKHDMMPLHYASQNGHCGVLELLLSRVSNVNAVDKRSQSPIHYAAQNGHVDAVSLLLKHNSAIEAPDKFDRCPIHYACQNGHLNVVRLLISE 258 HSP 8 Score: 115.931 bits (289), Expect = 8.666e-27 Identity = 55/162 (33.95%), Postives = 96/162 (59.26%), Query Frame = 2
Query: 281 WRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDR 766
RPI +AC D++ +L+ C++ +N +PIH+AC G ++IVKLL+ +C+IE C + +RPIH +C+ G+ IV+LL+ N + EA+D + RP+H AC G+ V LL+ C +++ K+N PI+ A +++++ D + + D+
Sbjct: 7 MRPIHYACQYGQLDLVKMLLMGMCDVEVFCKNDKRPIHYACESGDYDIVKLLLSYKCNIEVCDINLMRPIHYACQNGYHKIVELLLSNQADKEAKDKNNGRPLHHACRSGHANVVELLLNYYCDIEVHDKSNLRPIHYACLSGSYQIVEMLIDRCQIESLDK 168
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000017274.1 (SMESG000017274.1) HSP 1 Score: 366.696 bits (940), Expect = 1.404e-119 Identity = 215/561 (38.32%), Postives = 314/561 (55.97%), Query Frame = 2
Query: 59 QNLFLKMIDFDYFMSKVKLGIIDEVKISFMPEYLNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACY---------------------------------VGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE-----LKRQLFDRISRAFQVSNDFNLDQDIYSKCSND--FAKGRCIGRGSFGKVILYKLLKSG--HEFVVKSTYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-KTFCGTINYLAPEIIS---DQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELF 1603
+N+ ++ +F F++ +K G + + F E+L + D PIH AC GH E+VK LI+ IE+ RPI AC++ H + + +LI+++C+I ALD + W+PIH AC GH EIVKLLI+++CDIEA + RPIH++C +GH+ VKLLIEN C+IEA D K RPIH ACY G+ E +LLI NKC +D ++ +P+ A + T+++K++ + ++QL +IS+ ++ + D + D F KG IGRG+FGK+ YKL SG F +K E D + IE NI +++ L+H+RIV Y+G +Q K + MEY P+GSL I SI +I SKQI+EG++FLHGN+IIHRDI P NILLD NIKL DFG R + T ++ T GT N+ APE++ D Y ADIWSVGAT+ +M+ GR + ++ ++ KK+D +L + ++ + ++EMLN P R +AA LLK +LF
Sbjct: 63 RNIRIRNEEFKLFINAIKSGSAELFRRYFKEEFLERKDAGLRRPIHHACIAGHAEIVKLLIEHKCDIEALDWRNRRPIHLACYHGHSEAVKLLIEHKCDIEALDWDNWRPIHHACIAGHAEIVKLLIEHKCDIEALDWRNRRPIHLACYHGHSEAVKLLIENKCDIEALDEQKRRPIHLACYQGHSEAVKLLIEHNCDIEALDWWNQRPIHHACIQGHSEAVKLLIENKCDIDARDESGNSPMEFAMKSGNTEIIKILNEARLERQRQQQLERQISK-MGLTCESGCDHKLCPTSLRDKSFDKGSMIGRGAFGKI--YKLQGSGISSVFAIKRMNSEGVDEKYIEGNIYKFLPKLDHQRIVKYFGAIQTEKHLCLFMEYFPRGSLNTEISNKGSIETDNVIRYSKQILEGLKFLHGNKIIHRDIKPDNILLDEENNIKLADFGLGRSLMRTCGKSTRIDTTVGTANFTAPEVLEATDDAPYHESADIWSVGATVINMISGRPPYDNYPSFAVIFKVMTLKKLDLPKPQLMTAQIKSFIEEMLNPNPKKRSSAAQLLKLKLF 620
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000017274.1 (SMESG000017274.1) HSP 1 Score: 366.311 bits (939), Expect = 3.046e-119 Identity = 214/553 (38.70%), Postives = 309/553 (55.88%), Query Frame = 2
Query: 83 DFDYFMSKVKLGIIDEVKISFMPEYLNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQNKWQPIHWACRFGHWEIVKLLIKNRCDIEACGHDDLRPIHISCRYGHTNIVKLLIENNCNIEARDSSKWRPIHWACY---------------------------------VGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDE-----LKRQLFDRISRAFQVSNDFNLDQDIYSKCSND--FAKGRCIGRGSFGKVILYKLLKSG--HEFVVKSTYIETDDSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGSLLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANFNIKLTDFGFSRVVKDTATQNCA-KTFCGTINYLAPEIIS---DQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSRRMSTIVKEMLNYKPSNRPTAASLLKHELF 1603
+F F++ +K G + + F E+L + D PIH AC GH E+VK LI+ IE+ RPI AC++ H + + +LI+++C+I ALD + W+PIH AC GH EIVKLLI+++CDIEA + RPIH++C +GH+ VKLLIEN C+IEA D K RPIH ACY G+ E +LLI NKC +D ++ +P+ A + T+++K++ + ++QL +IS+ ++ + D + D F KG IGRG+FGK+ YKL SG F +K E D + IE NI +++ L+H+RIV Y+G +Q K + MEY P+GSL I SI +I SKQI+EG++FLHGN+IIHRDI P NILLD NIKL DFG R + T ++ T GT N+ APE++ D Y ADIWSVGAT+ +M+ GR + ++ ++ KK+D +L + ++ + ++EMLN P R +AA LLK +LF
Sbjct: 76 EFKLFINAIKSGSAELFRRYFKEEFLERKDAGLRRPIHHACIAGHAEIVKLLIEHKCDIEALDWRNRRPIHLACYHGHSEAVKLLIEHKCDIEALDWDNWRPIHHACIAGHAEIVKLLIEHKCDIEALDWRNRRPIHLACYHGHSEAVKLLIENKCDIEALDEQKRRPIHLACYQGHSEAVKLLIEHNCDIEALDWWNQRPIHHACIQGHSEAVKLLIENKCDIDARDESGNSPMEFAMKSGNTEIIKILNEARLERQRQQQLERQISK-MGLTCESGCDHKLCPTSLRDKSFDKGSMIGRGAFGKI--YKLQGSGISSVFAIKRMNSEGVDEKYIEGNIYKFLPKLDHQRIVKYFGAIQTEKHLCLFMEYFPRGSLNTEISNKGSIETDNVIRYSKQILEGLKFLHGNKIIHRDIKPDNILLDEENNIKLADFGLGRSLMRTCGKSTRIDTTVGTANFTAPEVLEATDDAPYHESADIWSVGATVINMISGRPPYDNYPSFAVIFKVMTLKKLDLPKPQLMTAQIKSFIEEMLNPNPKKRSSAAQLLKLKLF 625 The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024349 ID=SMED30024349|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1687bpback to top protein sequence of SMED30024349-orf-1 >SMED30024349-orf-1 ID=SMED30024349-orf-1|Name=SMED30024349-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=521bp MIDFDYFMSKVKLGIIDEVKISFMPEYLNKIDMNFDEPIHVACENGHEEVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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