E3 ubiquitin-protein ligase RNF13

Overview
NameE3 ubiquitin-protein ligase RNF13
Smed IDSMED30024336
Length (bp)1324
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of E3 ubiquitin-protein ligase RNF13 (SMED30024336) t-SNE clustered cells

Violin plots show distribution of expression levels for E3 ubiquitin-protein ligase RNF13 (SMED30024336) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of E3 ubiquitin-protein ligase RNF13 (SMED30024336) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for E3 ubiquitin-protein ligase RNF13 (SMED30024336) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30024336

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30024336SMESG000027627.1 Contig4768GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30024336SMESG000013169.1 Contig4768GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
parenchymal cellSMED30024336SMESG000013170.1 SMESG000013169.1 dd_Smed_v4_1923_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30024336SMESG000013169.1 Contig48844newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30024336SMESG000013169.1 Contig48844uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
ovarySMED30024336SMESG000013169.1 SMED30024336smed_20140614PMID:279364
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testisSMED30024336SMESG000013169.1 SMED30024336smed_20140614PMID:279364
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Human
Match: RNF13 (ring finger protein 13 [Source:HGNC Symbol;Acc:HGNC:10057])

HSP 1 Score: 145.206 bits (365), Expect = 1.058e-38
Identity = 110/321 (34.27%), Postives = 174/321 (54.21%), Query Frame = 2 
Query:   80 FFSIKILQMKSN----ILLVVLF---DIVFCDFKIVDTDLNESYYGFKDMNPIFG---PYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLI 1003
              SI +L + +     IL V LF   +++  +  I+  +   +   F D+   FG   P   L  +G+L  +KP  AC   + PP+ + +    I LI R +C F  K++ A+ +GY   I++N + + +  M +++ +  K I IPS  +   + N L+ +FT+ +      L          + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CAICLD+++DGDKLRILPC+HAYH  C+DPWL K K+ CP+CK ++ +P + D     D + +   +   +EHTPL+
Sbjct:    2 LLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGL--KGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGH---LILVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKG-DEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKV-VPSQGDSDSDTDSSQE---ENEVTEHTPLL 312
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Human
Match: RNF13 (ring finger protein 13 [Source:HGNC Symbol;Acc:HGNC:10057])

HSP 1 Score: 145.206 bits (365), Expect = 1.058e-38
Identity = 110/321 (34.27%), Postives = 174/321 (54.21%), Query Frame = 2 
Query:   80 FFSIKILQMKSN----ILLVVLF---DIVFCDFKIVDTDLNESYYGFKDMNPIFG---PYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLI 1003
              SI +L + +     IL V LF   +++  +  I+  +   +   F D+   FG   P   L  +G+L  +KP  AC   + PP+ + +    I LI R +C F  K++ A+ +GY   I++N + + +  M +++ +  K I IPS  +   + N L+ +FT+ +      L          + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CAICLD+++DGDKLRILPC+HAYH  C+DPWL K K+ CP+CK ++ +P + D     D + +   +   +EHTPL+
Sbjct:    2 LLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGL--KGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGH---LILVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKG-DEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKV-VPSQGDSDSDTDSSQE---ENEVTEHTPLL 312
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Human
Match: RNF167 (ring finger protein 167 [Source:HGNC Symbol;Acc:HGNC:24544])

HSP 1 Score: 143.28 bits (360), Expect = 1.317e-38
Identity = 99/284 (34.86%), Postives = 149/284 (52.46%), Query Frame = 2 
Query:  197 FKDMNPIFGPYFSLHD-EGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNF-ENRIFHM--NADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI-KIPG-------RXXXXXXXXXTPQTVPQPLASEHTPLINTS 1012
            F D+  +FG   S    +G+L EA P  AC     PP         IAL+ R +C F  K++ A+ +GY   +++N   N + +M  N++E  + I+IPS  +   +   LR  F + +  +  VL   DN  F    Y+I F G V +    +G     +  +   + Q NRL K  LK+IP   + KG D ++ CAICLD+++DGDKLR+LPC HAYH+ C+DPWL + ++ CPICK  + + PG            +  +  P+  P   ASE TPL+ +S
Sbjct:    3 FADLPALFGATLSQEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGAR--VLLVPDNT-FPLGYYLIPFTGIVGLLVLAMGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKG-DQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPRDHP---ASERTPLLGSS 279
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Human
Match: RNF167 (ring finger protein 167 [Source:HGNC Symbol;Acc:HGNC:24544])

HSP 1 Score: 143.665 bits (361), Expect = 1.926e-38
Identity = 103/311 (33.12%), Postives = 158/311 (50.80%), Query Frame = 2 
Query:  116 ILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHD-EGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNF-ENRIFHM--NADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI-KIPG-------RXXXXXXXXXTPQTVPQPLASEHTPLINTS 1012
            ++  VL+        I  T  + +   F D+  +FG   S    +G+L EA P  AC     PP         IAL+ R +C F  K++ A+ +GY   +++N   N + +M  N++E  + I+IPS  +   +   LR  F + +  +  VL   DN  F    Y+I F G V +    +G     +  +   + Q NRL K  LK+IP   + KG D ++ CAICLD+++DGDKLR+LPC HAYH+ C+DPWL + ++ CPICK  + + PG            +  +  P+  P   ASE TPL+ +S
Sbjct:   11 VVAAVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGAR--VLLVPDNT-FPLGYYLIPFTGIVGLLVLAMGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKG-DQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPRDHP---ASERTPLLGSS 314
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Human
Match: RNF167 (ring finger protein 167 [Source:HGNC Symbol;Acc:HGNC:24544])

HSP 1 Score: 143.665 bits (361), Expect = 1.926e-38
Identity = 103/311 (33.12%), Postives = 158/311 (50.80%), Query Frame = 2 
Query:  116 ILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHD-EGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNF-ENRIFHM--NADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI-KIPG-------RXXXXXXXXXTPQTVPQPLASEHTPLINTS 1012
            ++  VL+        I  T  + +   F D+  +FG   S    +G+L EA P  AC     PP         IAL+ R +C F  K++ A+ +GY   +++N   N + +M  N++E  + I+IPS  +   +   LR  F + +  +  VL   DN  F    Y+I F G V +    +G     +  +   + Q NRL K  LK+IP   + KG D ++ CAICLD+++DGDKLR+LPC HAYH+ C+DPWL + ++ CPICK  + + PG            +  +  P+  P   ASE TPL+ +S
Sbjct:   11 VVAAVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGAR--VLLVPDNT-FPLGYYLIPFTGIVGLLVLAMGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKG-DQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPRDHP---ASERTPLLGSS 314
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Celegans
Match: C18B12.4 (pep chromosome:WBcel235:X:15036662:15040602:-1 gene:WBGene00007666.1 transcript:C18B12.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C18B12.4)

HSP 1 Score: 104.76 bits (260), Expect = 3.525e-24
Identity = 90/286 (31.47%), Postives = 140/286 (48.95%), Query Frame = 2 
Query:  113 NILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNP---IFGPYFSLHDEGYLFEAKPSLACGNRIEPP--------LFNTTKR--KLIALIERGN----CTFGHKIIVAELSGY--TGVIIYNFENRI-FHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            ++ L+VLF I  C+ + V   +  + +G +++       G  F +    ++  ++ +L CG  +EP           N T R   L A + R N    C F H+  + + S Y    VI YN+  +    M   E    + IP  M+S      + ++F+ T   +  V    D   ++   Y+I FL  +   F L  I   ++ C +  K    RL K +LKKIP+KK+  G DP +TCAICL+ F  G+KLR LPC H +H NCID WL + ++ CP+CK +I
Sbjct:   11 SVGLLVLFGIYQCNAQYVVDVMRMTSFGEEELVHKCLAKGGNFGMDVSDFII-SEENLGCGVGVEPVDACGPVRIAQNHTTRCHNLFAFVSRSNISHPCKFSHQAFMVQNSTYPFRLVIFYNYPGQEPISMEGTELRDKVNIPVLMISHACKEEIAKKFSDTAGYRLRVRI--DPGYYELFRYLIPFLVVIVFCFALFLITLCVRGCVERRKLNKRRLSKRNLKKIPVKKYRLGDDP-DTCAICLESFASGEKLRHLPCRHVFHCNCIDVWLTQTRKICPLCKRKI 292
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Celegans
Match: H10E21.5 (pep chromosome:WBcel235:III:20531:23962:-1 gene:WBGene00019185.1 transcript:H10E21.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:H10E21.5)

HSP 1 Score: 68.5514 bits (166), Expect = 3.017e-12
Identity = 34/77 (44.16%), Postives = 46/77 (59.74%), Query Frame = 2 
Query:  686 KRQANRLRKCHLKKIPLKKFVKG--RDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            +R  N  RK  L +IP      G  ++    CA+CLD ++  D +R+LPC H YH +CIDPWLL+  R CP+CK  I
Sbjct:  197 RRLFNAARKA-LTRIPTMTITPGMTQELQSDCAVCLDPYQLQDVIRLLPCKHIYHKSCIDPWLLEH-RTCPMCKNDI 271
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Celegans
Match: plr-1 (Probable E3 ubiquitin-protein ligase plr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U2B7])

HSP 1 Score: 66.2402 bits (160), Expect = 1.484e-11
Identity = 23/48 (47.92%), Postives = 36/48 (75.00%), Query Frame = 2 
Query:  767 ETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            E C ICL+++++G +LR+L C H +H  C+DPWLL  KR CP+C++ +
Sbjct:  315 ERCVICLEEYEEGTELRVLFCGHEFHPKCVDPWLL-SKRRCPLCQFDV 361
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Celegans
Match: C01G6.4 (pep chromosome:WBcel235:II:9271265:9273042:-1 gene:WBGene00007226.1 transcript:C01G6.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C01G6.4)

HSP 1 Score: 61.2326 bits (147), Expect = 6.075e-11
Identity = 29/67 (43.28%), Postives = 42/67 (62.69%), Query Frame = 2 
Query:  698 NRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPIC 898
            NR+R   L++IP   F +G      CAIC+ DF+ G+++R LPC H++H  C+D WL+K    CP C
Sbjct:   72 NRIRGL-LEQIPADVF-RGDMTSNECAICMIDFEPGERIRFLPCMHSFHQECVDEWLMK-SFTCPSC 135
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Celegans
Match: toe-4 (Target Of ERK kinase MPK-1 [Source:UniProtKB/TrEMBL;Acc:Q9XUM8])

HSP 1 Score: 57.3806 bits (137), Expect = 1.005e-8
Identity = 25/60 (41.67%), Postives = 35/60 (58.33%), Query Frame = 2 
Query:  740 KFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIP 919
            K   G +  +TC +CL  F+DG+ ++ L CNH +H  CI  WL   KR CP+C+  I  P
Sbjct:  422 KKTDGEEDEDTCTVCLSSFEDGESIQKLRCNHVFHPECIYKWLDINKR-CPMCREEIDRP 480
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Fly
Match: gzl (gene:FBgn0037442 transcript:FBtr0081721)

HSP 1 Score: 122.479 bits (306), Expect = 6.914e-30
Identity = 88/248 (35.48%), Postives = 130/248 (52.42%), Query Frame = 2 
Query:  197 FKDMNPIFGPYFSLHD-EGYLFEAK-PSLACGNRIEPP-LFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLC-RDAYKRQANRLRKCHLKKIPLKKFVK--GRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPG 922
            F D+   FGP    +  + Y+  A+ P   C +   PP L      K +AL+ RG C F  KI VA+ + Y+ VI+YN E       + E+   I IPS  V   TG  L   FT        VL   D   F+  + +I+    +    F+I + + I  C R+  + + +RL K  LKK+P+ ++ K    + ++TC ICL+DF + DKLR+LPC+H YH +CIDPWL + +R CPICK ++   G
Sbjct:   42 FNDLPAQFGPNLPSNGLKVYVVPARRPYYGCDSLDRPPHLKYPPSAKFVALVARGECVFERKIRVAQNASYSAVIVYNNEGDDLEQMSAENITGIRIPSVFVGHTTGKALATYFT-----TEVVLIINDELPFNINTQLILPFSILIGMCFIIMVIYMIYKCIREQRRLRRHRLPKSMLKKLPVLRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKRKVFTKG 284
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Fly
Match: gzl (gene:FBgn0037442 transcript:FBtr0081722)

HSP 1 Score: 122.479 bits (306), Expect = 6.914e-30
Identity = 88/248 (35.48%), Postives = 130/248 (52.42%), Query Frame = 2 
Query:  197 FKDMNPIFGPYFSLHD-EGYLFEAK-PSLACGNRIEPP-LFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLC-RDAYKRQANRLRKCHLKKIPLKKFVK--GRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPG 922
            F D+   FGP    +  + Y+  A+ P   C +   PP L      K +AL+ RG C F  KI VA+ + Y+ VI+YN E       + E+   I IPS  V   TG  L   FT        VL   D   F+  + +I+    +    F+I + + I  C R+  + + +RL K  LKK+P+ ++ K    + ++TC ICL+DF + DKLR+LPC+H YH +CIDPWL + +R CPICK ++   G
Sbjct:   42 FNDLPAQFGPNLPSNGLKVYVVPARRPYYGCDSLDRPPHLKYPPSAKFVALVARGECVFERKIRVAQNASYSAVIVYNNEGDDLEQMSAENITGIRIPSVFVGHTTGKALATYFT-----TEVVLIINDELPFNINTQLILPFSILIGMCFIIMVIYMIYKCIREQRRLRRHRLPKSMLKKLPVLRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKRKVFTKG 284
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Fly
Match: gzl (gene:FBgn0037442 transcript:FBtr0081720)

HSP 1 Score: 122.479 bits (306), Expect = 6.914e-30
Identity = 88/248 (35.48%), Postives = 130/248 (52.42%), Query Frame = 2 
Query:  197 FKDMNPIFGPYFSLHD-EGYLFEAK-PSLACGNRIEPP-LFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLC-RDAYKRQANRLRKCHLKKIPLKKFVK--GRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPG 922
            F D+   FGP    +  + Y+  A+ P   C +   PP L      K +AL+ RG C F  KI VA+ + Y+ VI+YN E       + E+   I IPS  V   TG  L   FT        VL   D   F+  + +I+    +    F+I + + I  C R+  + + +RL K  LKK+P+ ++ K    + ++TC ICL+DF + DKLR+LPC+H YH +CIDPWL + +R CPICK ++   G
Sbjct:   42 FNDLPAQFGPNLPSNGLKVYVVPARRPYYGCDSLDRPPHLKYPPSAKFVALVARGECVFERKIRVAQNASYSAVIVYNNEGDDLEQMSAENITGIRIPSVFVGHTTGKALATYFT-----TEVVLIINDELPFNINTQLILPFSILIGMCFIIMVIYMIYKCIREQRRLRRHRLPKSMLKKLPVLRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKRKVFTKG 284
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Fly
Match: gzl (gene:FBgn0037442 transcript:FBtr0113198)

HSP 1 Score: 122.479 bits (306), Expect = 6.914e-30
Identity = 88/248 (35.48%), Postives = 130/248 (52.42%), Query Frame = 2 
Query:  197 FKDMNPIFGPYFSLHD-EGYLFEAK-PSLACGNRIEPP-LFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLC-RDAYKRQANRLRKCHLKKIPLKKFVK--GRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPG 922
            F D+   FGP    +  + Y+  A+ P   C +   PP L      K +AL+ RG C F  KI VA+ + Y+ VI+YN E       + E+   I IPS  V   TG  L   FT        VL   D   F+  + +I+    +    F+I + + I  C R+  + + +RL K  LKK+P+ ++ K    + ++TC ICL+DF + DKLR+LPC+H YH +CIDPWL + +R CPICK ++   G
Sbjct:   42 FNDLPAQFGPNLPSNGLKVYVVPARRPYYGCDSLDRPPHLKYPPSAKFVALVARGECVFERKIRVAQNASYSAVIVYNNEGDDLEQMSAENITGIRIPSVFVGHTTGKALATYFT-----TEVVLIINDELPFNINTQLILPFSILIGMCFIIMVIYMIYKCIREQRRLRRHRLPKSMLKKLPVLRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKRKVFTKG 284
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Fly
Match: gol (gene:FBgn0004919 transcript:FBtr0300178)

HSP 1 Score: 76.6406 bits (187), Expect = 9.070e-15
Identity = 65/209 (31.10%), Postives = 97/209 (46.41%), Query Frame = 2 
Query:  332 IALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMNADESDKDIFIPSRMVSSV-TGNRLRQQFTFT------------ESRQNFVLFFFDNEG---FDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLK--KFVKGRD-PFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICK 901
            IAL+ RG CTF  K+         GVIIYN + ++  +   +    I   +R +++V T   + Q  + T            E R+        N     F S S+I++ +  +    F     F     +D   R    + K  + KIP K  KF   +D   + CAIC++ +K  D +RILPC H +H NCIDPWL++  R CP+CK
Sbjct:  142 IALVRRGRCTFEEKVKHVYQQNAAGVIIYN-DKQVMQLEKMQ----IKGKTRNIAAVITYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSDEKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEH-RTCPMCK 344
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Zebrafish
Match: rnf167 (ring finger protein 167 [Source:ZFIN;Acc:ZDB-GENE-110126-2])

HSP 1 Score: 132.494 bits (332), Expect = 4.485e-34
Identity = 97/285 (34.04%), Postives = 146/285 (51.23%), Query Frame = 2 
Query:  119 LLVVLFDIVFCDFK-------IVDTDLNESYYGFKDMNPIFGPYFSLHD-EGYLFEAKPSLACGNRIEPPLFNTT------KRKLIALIERGNCTFGHKIIVAELSGYTGVIIYN-FENRIFHMN-ADES-DKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKR-QANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIP 919
            L V +  I+FC          I     N +   F+D+  +FG         G L EA+P  AC   I+PP  + T        K I LI R +C F  K+  A+ +GY+  I++N + N + +M  ++E+  ++I IPS   S      L +       +  +V+     E     SY ++    V     ++ +   I  C    KR + NRL K  LKKIP+ KF KG D ++ CAICLD++++GDKLR+LPC+HAYH+ C+DPWL + K+ CP+CK R+  P
Sbjct:    8 LAVSVLLIIFCTLVPSPGQAYIYAHYSNMTSMLFEDLPALFGSALPKDGLMGVLIEARPQNAC-TPIDPPPASPTPADPNSTTKYIVLIRRYDCNFDVKVYHAQQAGYSAAIVHNMYSNSLLNMGYSNETIAEEISIPSVFTSFFASQMLHK---IIPEKGAYVVL--KPEFSFPLSYYLIPFTGVVCMIIIVMVIIMIVRCVQHRKRLRKNRLSKEQLKKIPIHKFNKG-DSYDVCAICLDEYEEGDKLRVLPCSHAYHSRCVDPWLTQTKKTCPVCKQRVTRP 285
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Zebrafish
Match: rnf13 (ring finger protein 13 [Source:ZFIN;Acc:ZDB-GENE-040426-772])

HSP 1 Score: 131.724 bits (330), Expect = 5.569e-34
Identity = 88/267 (32.96%), Postives = 145/267 (54.31%), Query Frame = 2 
Query:  245 EGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLINTSQPSNSTRY 1036
            +G+L  A+P  AC     PP         I LI R +C F  K++ A+ +GY   I++N + + +  M +++ D  K I IPS  +     N L++ + + +     ++  F       + Y+I FL  V I   LI +    K  +D ++ + +RLRK  LKK+P+ KF KG D ++ CAICLD++++G++LR+LPC+HAYH  C+DPWL K K+ CP+CK ++ +P   D     D           SE+TPL+ +   +++  +
Sbjct:   65 KGFLIGARPENACVPIEPPPQRENLSSAFIVLIRRFDCNFDIKVLHAQKAGYKAAIVHNVDSDDLISMGSEDLDILKQIDIPSVFIGEEAANSLKEDYIYEKGGHVILMPDF---SLPLEYYLIPFLIIVGICLILIVVFMITKFVQDRHRARRSRLRKDQLKKLPIHKFKKG-DSYDVCAICLDEYEEGERLRVLPCSHAYHCKCVDPWLTKTKKTCPVCKQKV-VPSDGDSESDSDSVDSGGEDNEVSENTPLLRSLASTSAHSF 326
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Zebrafish
Match: rnf13 (ring finger protein 13 [Source:ZFIN;Acc:ZDB-GENE-040426-772])

HSP 1 Score: 91.6633 bits (226), Expect = 1.570e-20
Identity = 67/201 (33.33%), Postives = 111/201 (55.22%), Query Frame = 2 
Query:  245 EGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHA 838
            +G+L  A+P  AC     PP         I LI R +C F  K++ A+ +GY   I++N + + +  M +++ D  K I IPS  +     N L++ + + +     ++  F       + Y+I FL  V I   LI +    K  +D ++ + +RLRK  LKK+P+ KF KG D ++ CAICLD++++G++LR+LPC+HA
Sbjct:   65 KGFLIGARPENACVPIEPPPQRENLSSAFIVLIRRFDCNFDIKVLHAQKAGYKAAIVHNVDSDDLISMGSEDLDILKQIDIPSVFIGEEAANSLKEDYIYEKGGHVILMPDF---SLPLEYYLIPFLIIVGICLILIVVFMITKFVQDRHRARRSRLRKDQLKKLPIHKFKKG-DSYDVCAICLDEYEEGERLRVLPCSHA 261
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Zebrafish
Match: rnf150a (ring finger protein 150a [Source:ZFIN;Acc:ZDB-GENE-060213-1])

HSP 1 Score: 83.1889 bits (204), Expect = 7.799e-17
Identity = 68/244 (27.87%), Postives = 108/244 (44.26%), Query Frame = 2 
Query:  248 GYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMNADESDKDIFIPSRMVSSVTGNRL-----RQQFTFTESRQNFVLFFFDNEG--------------FDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGR----DPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            G++F  +   AC      PL + +    IALI +GNCTF  KI  A     + V+I+N       + +  S+  I +P      V    +     R+     E  +N  +    + G              F S S+I++ +  ++   F     F     RD  +R+     K  + K+ ++   KG       F+ CA+C++D+K  D +RILPC H +H NC+DPW L+  R CP+CK  I
Sbjct:   77 GFVFMPQDRQACDGNTRFPLPHPSI-PWIALIAKGNCTFREKIRHAAALNASAVVIFN-------VGSSNSNDTITMPHHGTGDVVAIMIPEPKGREIMALLE--KNITVAMHISIGTRNLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRSQRRLGDAAKKAISKLQVRTIRKGDKETDSDFDNCAVCIEDYKPNDVVRILPCRHVFHRNCVDPW-LQDHRTCPMCKMNI 309
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Zebrafish
Match: rnf130 (ring finger protein 130 [Source:ZFIN;Acc:ZDB-GENE-050522-525])

HSP 1 Score: 73.9442 bits (180), Expect = 7.800e-14
Identity = 59/210 (28.10%), Postives = 95/210 (45.24%), Query Frame = 2 
Query:  332 IALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMN-ADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFD---------NEG---FDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKG---RDP-FETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            +A+++RG CTF  KI+ A     + VIIYN   +   +  A E   DI   + M++   G  +     F E  Q  ++             N G   F S S+I++ +   +   F           RD  +R+     K  + K+  +   +G    +P F  CA+C++ ++  D +RILPC H +H  C+DPW L +   CP+CK  I
Sbjct:   78 VAIMQRGKCTFKEKILKAAAFNASAVIIYNNNTKEDTVTMAHEGTGDIV--AVMITESFGKEI---LGFLEKNQTVLVSVIVGSRGMPKNINRGSLVFVSISFIVLMIISSAWLIFYFIQKIRDTSARDRSQRRLGDAAKKAISKLTTRTVKRGDKETEPDFNHCAVCIEGYQLNDVVRILPCKHVFHKMCVDPW-LNEHCTCPMCKLNI 281
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Xenopus
Match: rnf13 (ring finger protein 13 [Source:NCBI gene;Acc:493377])

HSP 1 Score: 135.576 bits (340), Expect = 2.378e-35
Identity = 86/225 (38.22%), Postives = 134/225 (59.56%), Query Frame = 2 
Query:  248 GYLFEAKPSLACGNRIEPPLF-NTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            GY+  AKP  AC     PPL  + T    I LI+R  C F  K++ A+ +G+   ++YN + + +  M +++ D  K I IPS  +   +   L+++F++   +  +++   D      + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CA+CLD++++GDKLRILPC+HAYH  C+DPWL K K+ CP+CK ++
Sbjct:   39 GYIVTAKPENACQPISPPPLLRDNTSSVFIVLIKRLECNFDLKVLNAQKAGFKAAVVYNVDSDDLISMGSNDVDILKQIDIPSVFIGESSARFLKEEFSW--EKGGYIVLVPD-LTLPLEYYLIPFLIIVGICLVLIVIFMITKFVQDRHRARRNRLRKDQLKKLPIHKFKKG-DEYDVCAVCLDEYEEGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKV 259
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Xenopus
Match: rnf13 (ring finger protein 13 [Source:NCBI gene;Acc:493377])

HSP 1 Score: 135.576 bits (340), Expect = 3.598e-35
Identity = 86/226 (38.05%), Postives = 135/226 (59.73%), Query Frame = 2 
Query:  245 EGYLFEAKPSLACGNRIEPPLF-NTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            +GY+  AKP  AC     PPL  + T    I LI+R  C F  K++ A+ +G+   ++YN + + +  M +++ D  K I IPS  +   +   L+++F++   +  +++   D      + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CA+CLD++++GDKLRILPC+HAYH  C+DPWL K K+ CP+CK ++
Sbjct:   65 KGYIVTAKPENACQPISPPPLLRDNTSSVFIVLIKRLECNFDLKVLNAQKAGFKAAVVYNVDSDDLISMGSNDVDILKQIDIPSVFIGESSARFLKEEFSW--EKGGYIVLVPD-LTLPLEYYLIPFLIIVGICLVLIVIFMITKFVQDRHRARRNRLRKDQLKKLPIHKFKKG-DEYDVCAVCLDEYEEGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKV 286
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Xenopus
Match: rnf13 (ring finger protein 13 [Source:NCBI gene;Acc:493377])

HSP 1 Score: 135.961 bits (341), Expect = 3.721e-35
Identity = 86/226 (38.05%), Postives = 135/226 (59.73%), Query Frame = 2 
Query:  245 EGYLFEAKPSLACGNRIEPPLF-NTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            +GY+  AKP  AC     PPL  + T    I LI+R  C F  K++ A+ +G+   ++YN + + +  M +++ D  K I IPS  +   +   L+++F++   +  +++   D      + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CA+CLD++++GDKLRILPC+HAYH  C+DPWL K K+ CP+CK ++
Sbjct:   81 KGYIVTAKPENACQPISPPPLLRDNTSSVFIVLIKRLECNFDLKVLNAQKAGFKAAVVYNVDSDDLISMGSNDVDILKQIDIPSVFIGESSARFLKEEFSW--EKGGYIVLVPD-LTLPLEYYLIPFLIIVGICLVLIVIFMITKFVQDRHRARRNRLRKDQLKKLPIHKFKKG-DEYDVCAVCLDEYEEGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKV 302
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Xenopus
Match: RNF167 (ring finger protein 167 [Source:NCBI gene;Acc:100379947])

HSP 1 Score: 129.028 bits (323), Expect = 9.081e-34
Identity = 75/210 (35.71%), Postives = 116/210 (55.24%), Query Frame = 2 
Query:  299 PPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIF---HMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVL--FFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKR-QANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            PP  N T    I LI R +C F  K++ A+L+GY   I++N    +      N +   + I IPS      +G  L   F++  +   +++  ++F      S  Y ++    V     ++     +  C    KR + NRL K  LKKIP+ KF KG D ++ CAICL+++++GDKLR+LPC+HAYH +C+DPWL K K++CP+CK R+
Sbjct:    1 PPTDNGTS--FIVLIRRNDCNFDTKVLHAQLAGYNAAIVHNVGADLLLRMGWNDESIRRQIRIPSVFTGESSGRSLLANFSYYNNSHIYLVPDYYF------SLGYYLIPFIVVVSVVIVVMCIVMVVRCAQYRKRMRRNRLSKEQLKKIPIHKFKKG-DDYDVCAICLEEYEEGDKLRVLPCSHAYHCSCVDPWLTKTKKSCPVCKNRV 201
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Xenopus
Match: rnf130 (ring finger protein 130 [Source:NCBI gene;Acc:100124963])

HSP 1 Score: 83.1889 bits (204), Expect = 1.128e-16
Identity = 63/217 (29.03%), Postives = 99/217 (45.62%), Query Frame = 2 
Query:  323 RKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENR-----IFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTE------------SRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKG---RDP-FETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            +  IAL++RGNCTF  KI+ A     + V+IYN  ++     + H    E      I + M+S   G   R+  ++ E            SR     F   +  F S S+I++ +   +   F           RD  +R+     K  + K+  +   KG    DP F+ CA+C++ +K  D +R+LPC H +H  C+DPW L +   CP+CK  I
Sbjct:  102 KHWIALLQRGNCTFKEKILRAASHNASAVVIYNNNSKEETVTMTHQGTGE------IVAIMISEARG---REILSYVERNISVLMAIAVGSRNQHKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTSARDRNQRRLGDAAKKAIGKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDIVRVLPCKHVFHKVCVDPW-LSEHCTCPMCKLNI 308
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Mouse
Match: Rnf167 (ring finger protein 167 [Source:MGI Symbol;Acc:MGI:1917760])

HSP 1 Score: 150.984 bits (380), Expect = 2.720e-41
Identity = 95/268 (35.45%), Postives = 144/268 (53.73%), Query Frame = 2 
Query:  116 ILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHDEG---YLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNF-ENRIFHM--NADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICK 901
            ++  VL+        I  T  + +   F D+  +FG   +L DEG   +L EA P  ACG    PP         IAL+ R +C F  K++ A+ +GY   +++N   N + +M  N++E  + I+IPS  +   +   LR  F + +  +  VL   DN  F    Y+I F G V +    +G    ++  +   + Q NRL K  LK+IP   + KG D ++ CAICLD+++DGDKLR+LPC HAYH+ C+DPWL + ++ CPICK
Sbjct:   11 VVATVLWGAAPVRGLIRATSEHNASMDFADLPALFGA--TLSDEGLQGFLVEAHPENACGPIAPPPSAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSAEYLRALFVYEKGAR--VLLVPDNS-FPLGYYLIPFTGIVGLLVLAMGTVLIVRCIQHRKRLQRNRLTKEQLKQIPTHDYQKG-DEYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICK 272
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Mouse
Match: Rnf13 (ring finger protein 13 [Source:MGI Symbol;Acc:MGI:1346341])

HSP 1 Score: 149.058 bits (375), Expect = 2.819e-40
Identity = 115/331 (34.74%), Postives = 179/331 (54.08%), Query Frame = 2 
Query:   80 FFSIKILQMKSN----ILLVVLF---DIVFCDFKIVDTDLNESYYGFKDMNPIFG---PYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLINTSQPSNSTR 1033
              SI +L + +     IL V LF   +++  +  I+  +   +   F+D+   FG   P   L  +G+L  +KP  AC   + PPL + +    I LI R +C F  K++ A+ +GY   I++N + + +  M +++ D  K I IPS  +   + N L+ +FT+ +      +          + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CAICL++++DGDKLRILPC+HAYH  C+DPWL K K+ CP+CK ++ +P + D     D + +   +   SEHTPL+    PS S R
Sbjct:    2 LLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFEDLPARFGYRLPAEGL--KGFLINSKPENACEPIVPPPLKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIDTLKKIDIPSVFIGESSANSLKDEFTYEKGGH---IILVPELSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRNRRNRLRKDQLKKLPVHKFKKG-DEYDVCAICLEEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKV-VPSQGDSDSDTDSSQE---ENQVSEHTPLL---PPSASAR 319
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Mouse
Match: Rnf13 (ring finger protein 13 [Source:MGI Symbol;Acc:MGI:1346341])

HSP 1 Score: 102.834 bits (255), Expect = 1.859e-24
Identity = 86/270 (31.85%), Postives = 141/270 (52.22%), Query Frame = 2 
Query:   80 FFSIKILQMKSN----ILLVVLF---DIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHD-EGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCI 856
              SI +L + +     IL V LF   +++  +  I+  +   +   F+D+   FG        +G+L  +KP  AC   + PPL + +    I LI R +C F  K++ A+ +GY   I++N + + +  M +++ D  K I IPS  +   + N L+ +FT+ +      +          + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CAICL++++DGDKLRILPC+H    + +
Sbjct:    2 LLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFEDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPLKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIDTLKKIDIPSVFIGESSANSLKDEFTYEKGGH---IILVPELSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRNRRNRLRKDQLKKLPVHKFKKG-DEYDVCAICLEEYEDGDKLRILPCSHGMSTHTV 267
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Mouse
Match: Rnf13 (ring finger protein 13 [Source:MGI Symbol;Acc:MGI:1346341])

HSP 1 Score: 103.605 bits (257), Expect = 4.139e-24
Identity = 88/266 (33.08%), Postives = 141/266 (53.01%), Query Frame = 2 
Query:   80 FFSIKILQMKSN----ILLVVLF---DIVFCDFKIVDTDLNESYYGFKDMNPIFG---PYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHA 838
              SI +L + +     IL V LF   +++  +  I+  +   +   F+D+   FG   P   L  +G+L  +KP  AC   + PPL + +    I LI R +C F  K++ A+ +GY   I++N + + +  M +++ D  K I IPS  +   + N L+ +FT+ +      +          + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CAICL++++DGDKLRILPC+H 
Sbjct:    2 LLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFEDLPARFGYRLPAEGL--KGFLINSKPENACEPIVPPPLKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIDTLKKIDIPSVFIGESSANSLKDEFTYEKGGH---IILVPELSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRNRRNRLRKDQLKKLPVHKFKKG-DEYDVCAICLEEYEDGDKLRILPCSHG 261
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Mouse
Match: Rnf128 (ring finger protein 128 [Source:MGI Symbol;Acc:MGI:1914139])

HSP 1 Score: 86.2705 bits (212), Expect = 5.969e-18
Identity = 66/214 (30.84%), Postives = 97/214 (45.33%), Query Frame = 2 
Query:  308 FNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYN---FENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEG---------FDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPF----ETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICK 901
            F  T +  IALIERGNCTF  KI  A  S    V+IYN     N+   M A+    DI   + M+ ++ G ++ Q       +   V+      G         F S S+ I+    V    F           +   +RQ     K  + K+ L+   +G        ++CA+C++ +K  D +RIL CNH +H  C+DPWLL+  R CP+CK
Sbjct:   84 FTNTAKPWIALIERGNCTFSEKIQTASRSNANAVVIYNSPETGNQTIQM-ANFGAGDIV--AIMIGNLKGTKILQSIQ-RGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGKLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEH-RTCPMCK 292
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. UniProt/SwissProt
Match: sp|Q91XF4|RN167_MOUSE (E3 ubiquitin-protein ligase RNF167 OS=Mus musculus OX=10090 GN=Rnf167 PE=2 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 1.903e-40
Identity = 95/268 (35.45%), Postives = 144/268 (53.73%), Query Frame = 2 
Query:  116 ILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHDEG---YLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNF-ENRIFHM--NADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICK 901
            ++  VL+        I  T  + +   F D+  +FG   +L DEG   +L EA P  ACG    PP         IAL+ R +C F  K++ A+ +GY   +++N   N + +M  N++E  + I+IPS  +   +   LR  F + +  +  VL   DN  F    Y+I F G V +    +G    ++  +   + Q NRL K  LK+IP   + KG D ++ CAICLD+++DGDKLR+LPC HAYH+ C+DPWL + ++ CPICK
Sbjct:   11 VVATVLWGAAPVRGLIRATSEHNASMDFADLPALFGA--TLSDEGLQGFLVEAHPENACGPIAPPPSAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSAEYLRALFVYEKGAR--VLLVPDNS-FPLGYYLIPFTGIVGLLVLAMGTVLIVRCIQHRKRLQRNRLTKEQLKQIPTHDYQKG-DEYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICK 272
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. UniProt/SwissProt
Match: sp|O54965|RNF13_MOUSE (E3 ubiquitin-protein ligase RNF13 OS=Mus musculus OX=10090 GN=Rnf13 PE=1 SV=2)

HSP 1 Score: 149.058 bits (375), Expect = 1.972e-39
Identity = 115/331 (34.74%), Postives = 179/331 (54.08%), Query Frame = 2 
Query:   80 FFSIKILQMKSN----ILLVVLF---DIVFCDFKIVDTDLNESYYGFKDMNPIFG---PYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLINTSQPSNSTR 1033
              SI +L + +     IL V LF   +++  +  I+  +   +   F+D+   FG   P   L  +G+L  +KP  AC   + PPL + +    I LI R +C F  K++ A+ +GY   I++N + + +  M +++ D  K I IPS  +   + N L+ +FT+ +      +          + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CAICL++++DGDKLRILPC+HAYH  C+DPWL K K+ CP+CK ++ +P + D     D + +   +   SEHTPL+    PS S R
Sbjct:    2 LLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFEDLPARFGYRLPAEGL--KGFLINSKPENACEPIVPPPLKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIDTLKKIDIPSVFIGESSANSLKDEFTYEKGGH---IILVPELSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRNRRNRLRKDQLKKLPVHKFKKG-DEYDVCAICLEEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKV-VPSQGDSDSDTDSSQE---ENQVSEHTPLL---PPSASAR 319
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. UniProt/SwissProt
Match: sp|Q66HG0|RNF13_RAT (E3 ubiquitin-protein ligase RNF13 OS=Rattus norvegicus OX=10116 GN=Rnf13 PE=2 SV=1)

HSP 1 Score: 149.058 bits (375), Expect = 2.013e-39
Identity = 115/331 (34.74%), Postives = 179/331 (54.08%), Query Frame = 2 
Query:   80 FFSIKILQMKSN----ILLVVLF---DIVFCDFKIVDTDLNESYYGFKDMNPIFG---PYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLINTSQPSNSTR 1033
              SI +L + +     IL V LF   +++  +  I+  +   +   F+D+   FG   P   L  +G+L  +KP  AC   + PPL + +    I LI R +C F  K++ A+ +GY   I++N + + +  M +++ D  K I IPS  +   + N L+ +FT+ +      +          + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CAICL++++DGDKLRILPC+HAYH  C+DPWL K K+ CP+CK ++ +P + D     D + +   +   SEHTPL+    PS S R
Sbjct:    2 LLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFEDLPARFGYRLPAEGL--KGFLINSKPENACEPIVPPPLKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIDILKKIDIPSVFIGESSANSLKDEFTYEKGGH---VILVPELSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRNRRNRLRKDQLKKLPVHKFKKG-DEYDVCAICLEEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKV-VPSQGDSDSDTDSSQE---ENQVSEHTPLL---PPSASAR 319
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. UniProt/SwissProt
Match: sp|Q0VD51|RNF13_BOVIN (E3 ubiquitin-protein ligase RNF13 OS=Bos taurus OX=9913 GN=RNF13 PE=2 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 6.288e-39
Identity = 111/321 (34.58%), Postives = 176/321 (54.83%), Query Frame = 2 
Query:   80 FFSIKILQMKSN----ILLVVLF---DIVFCDFKIVDTDLNESYYGFKDMNPIFG---PYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLI 1003
              SI +L + +     IL V LF   +++  +  I+  +   +   F D+   FG   P   L  +G+L  +KP  AC   + PP+ + +    I LI R +C F  K++ A+ +GY   I++N + + +  M +++ +  K I IPS  +   + N L+ +FT+ +     ++  F       + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CAICLD+++DGDKLRILPC+HAYH  C+DPWL K K+ CP+CK ++ +P + D     D + +   +   SEHTPL+
Sbjct:    2 LLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGL--KGFLINSKPENACEPIVPPPVRDNSSGTFIVLIRRLDCNFDEKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHIILVPEF---SLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKG-DEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKV-VPSQGDSDSDTDSSQE---ENEVSEHTPLL 312
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. UniProt/SwissProt
Match: sp|Q5RCV8|RNF13_PONAB (E3 ubiquitin-protein ligase RNF13 OS=Pongo abelii OX=9601 GN=RNF13 PE=2 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 5.079e-38
Identity = 110/321 (34.27%), Postives = 174/321 (54.21%), Query Frame = 2 
Query:   80 FFSIKILQMKSN----ILLVVLF---DIVFCDFKIVDTDLNESYYGFKDMNPIFG---PYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLI 1003
              SI +L + +     IL V LF   +++  +  I+  +   +   F D+   FG   P   L  +G+L  +KP  AC   + PP+ + +    I LI R +C F  K++ A+ +GY   I++N + + +  M +++ +  K I IPS  +   + N L+ +FT+ +      L          + Y+I FL  V I   LI I    K  +D ++ + NRLRK  LKK+P+ KF KG D ++ CAICLD+++DGDKLRILPC+HAYH  C+DPWL K K+ CP+CK ++ +P + D     D + +   +   +EHTPL+
Sbjct:    2 LLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGL--KGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGH---LILVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKG-DEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKV-VPSQGDSDSDTDSSQE---ENEVTEHTPLL 312
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. TrEMBL
Match: A0A433ST64 (RING-type domain-containing protein OS=Elysia chlorotica OX=188477 GN=EGW08_019810 PE=4 SV=1)

HSP 1 Score: 165.236 bits (417), Expect = 1.565e-41
Identity = 95/284 (33.45%), Postives = 164/284 (57.75%), Query Frame = 2 
Query:   86 SIKILQMKSNILLVVLFDIVF---CDFKIVDTDLNESYYGFKDMNPIFGPYFSLHDEG---YLFEAKPSLACGNRIEPPLFNTTKRKLIALIERG-NCTFGHKIIVAELSGYTGVIIYNFENR--IFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            +++ + +  ++L+  L+ +      D  ++D++ N +   F DM   FG  F L  EG   ++  + P+ ACG    PP+        + ++ RG +C F  K++ AE  GY  VI++N+E    +  M  +E+   + IPS  V    G RL+ ++ +T   + + +   +++  + + Y+  F+  VS+ F ++ I   +KL ++  KR+ NRL K  LKKIP +KF KG D ++TCAICLD+++DG+++R+LPC+H YH  CIDPWL K ++ CP+CK R+
Sbjct:   11 ALRQINLGFHLLVASLWMLASPGNADILVIDSETNVTSPVFHDMTSAFGREFPL--EGLSCHVVYSSPADACGPVQAPPVPREDNIGWVLIVARGGHCGFADKVLAAEQQGYDAVIVHNYEGHEALVKMYGNENGSFVNIPSTFVGWQEGMRLKNEYNYT--YRKYYVKILEDQDINYRLYLWPFVVVVSVCFLMVMIFVVVKLIKEHAKRRGNRLSKRKLKKIPTRKFQKG-DYYDTCAICLDEYEDGERIRVLPCDHVYHTKCIDPWLTKNRKTCPVCKRRV 289
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. TrEMBL
Match: A0A0B7AC54 (RING-type domain-containing protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF109633 PE=4 SV=1)

HSP 1 Score: 162.155 bits (409), Expect = 3.723e-41
Identity = 105/271 (38.75%), Postives = 162/271 (59.78%), Query Frame = 2 
Query:  206 MNPIFGPYFSLHD-EGYLFEAKP-SLACGNRIEPPLFNTTKRKLIALIERG-NCTFGHKIIVAELSGYTGVIIYNFENR--IFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLI 1003
            M   FGP F     EG+L  A+P S ACG  ++PP     K   I LI RG NC F  K++ A+L  Y+  I++N++++  +  M  D +   + IPS  V    G  L++ +++  + + +++   ++E  D  SY+  FL  ++I   ++ I   +K  RD   R+ +RL   HLKKIP++K+ KG D ++TCAICL+++++G+K+R+LPC+H YH  CIDPWL K K+ CP+CK R+ IPGRD DS+S  D          SE+TPL+
Sbjct:    1 MQAKFGPDFPYDGLEGHLLYAEPDSQACGP-VKPPPSTNNKYFWILLIARGGNCQFSDKVLNAQLHNYSAAIVHNYDHKDGLIPMGGDGTR--VSIPSTFVGWKDGMELKRLYSYY-THKEYIIRILEDESIDYTSYLWPFLLVLAICILMVMIFLILKFLRDYASRRFSRLSNKHLKKIPIRKYKKG-DYYDTCAICLEEYEEGEKIRVLPCDHVYHRKCIDPWLTKNKKTCPVCKRRV-IPGRDADSESGSDADTGGTTAGGSENTPLL 265
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. TrEMBL
Match: A0A0B7ACF4 (RING-type domain-containing protein OS=Arion vulgaris OX=1028688 GN=ORF109629 PE=4 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 4.426e-41
Identity = 105/271 (38.75%), Postives = 162/271 (59.78%), Query Frame = 2 
Query:  206 MNPIFGPYFSLHD-EGYLFEAKP-SLACGNRIEPPLFNTTKRKLIALIERG-NCTFGHKIIVAELSGYTGVIIYNFENR--IFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLI 1003
            M   FGP F     EG+L  A+P S ACG  ++PP     K   I LI RG NC F  K++ A+L  Y+  I++N++++  +  M  D +   + IPS  V    G  L++ +++  + + +++   ++E  D  SY+  FL  ++I   ++ I   +K  RD   R+ +RL   HLKKIP++K+ KG D ++TCAICL+++++G+K+R+LPC+H YH  CIDPWL K K+ CP+CK R+ IPGRD DS+S  D          SE+TPL+
Sbjct:    1 MQAKFGPDFPYDGLEGHLLYAEPDSQACGP-VKPPPSTNNKYFWILLIARGGNCQFSDKVLNAQLHNYSAAIVHNYDHKDGLIPMGGDGTR--VSIPSTFVGWKDGMELKRLYSYY-THKEYIIRILEDESIDYTSYLWPFLLVLAICILMVMIFLILKFLRDYASRRFSRLSNKHLKKIPIRKYKKG-DYYDTCAICLEEYEEGEKIRVLPCDHVYHRKCIDPWLTKNKKTCPVCKRRV-IPGRDADSESGSDADTGGTTAGGSENTPLL 265
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. TrEMBL
Match: A0A4S2KYW3 (RING-type domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_010455 PE=4 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 4.903e-41
Identity = 97/284 (34.15%), Postives = 152/284 (53.52%), Query Frame = 2 
Query:  119 LLVVLFDIVFCDFKIVDTDL-NESYYGFKDMNPIFGPYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRK--------------LIALIERGNCTFGHKIIVAELSGYTGVIIYN-FENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPG 922
            LL+VL D+V     +++  + +     F+D    FGP    H +G+L  A P  AC      P+ N T+                 IALI+RG+C F  K+  A+++GY+  I+YN  ++ IF M  +     I IPS MV    G +L Q +  +   + +++          +  ++  L  V I   ++   F   LC    + +  RL K HL+++  K+FVKG+DP+ETC ICL+D+K+ +KLR+LPC+HA+H NCIDPWLL+ +R CP+C   + +PG
Sbjct:    7 LLLVLCDLVQSTVYVMNNGIFSVIITSFEDAVSQFGPEL-FHVDGFLLIASPPNACTKL--QPVHNRTRLNSSSFTVPTEISDVPFIALIQRGDCHFDTKVFNAQMAGYSAAIVYNDVDHVIFPMKGNMVADQIIIPSVMVDKSAGEQL-QSYALSNDSRKYLVSVVSFYSLPLKYVLLSLLVLVGISLLILIGCFAAHLCNLWRRIRRGRLSKRHLRRLETKRFVKGQDPYETCPICLEDYKEREKLRLLPCHHAFHINCIDPWLLQNRRRCPVCNRTVDLPG 286
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. TrEMBL
Match: A0A4S2KY99 (RING-type domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_010455 PE=4 SV=1)

HSP 1 Score: 161.384 bits (407), Expect = 9.038e-41
Identity = 97/284 (34.15%), Postives = 152/284 (53.52%), Query Frame = 2 
Query:  119 LLVVLFDIVFCDFKIVDTDL-NESYYGFKDMNPIFGPYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRK--------------LIALIERGNCTFGHKIIVAELSGYTGVIIYN-FENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPG 922
            LL+VL D+V     +++  + +     F+D    FGP    H +G+L  A P  AC      P+ N T+                 IALI+RG+C F  K+  A+++GY+  I+YN  ++ IF M  +     I IPS MV    G +L Q +  +   + +++          +  ++  L  V I   ++   F   LC    + +  RL K HL+++  K+FVKG+DP+ETC ICL+D+K+ +KLR+LPC+HA+H NCIDPWLL+ +R CP+C   + +PG
Sbjct:    7 LLLVLCDLVQSTVYVMNNGIFSVIITSFEDAVSQFGPEL-FHVDGFLLIASPPNACTKL--QPVHNRTRLNSSSFTVPTEISDVPFIALIQRGDCHFDTKVFNAQMAGYSAAIVYNDVDHVIFPMKGNMVADQIIIPSVMVDKSAGEQL-QSYALSNDSRKYLVSVVSFYSLPLKYVLLSLLVLVGISLLILIGCFAAHLCNLWRRIRRGRLSKRHLRRLETKRFVKGQDPYETCPICLEDYKEREKLRLLPCHHAFHINCIDPWLLQNRRRCPVCNRTVDLPG 286
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Cavefish
Match: rnf167 (ring finger protein 167 [Source:NCBI gene;Acc:103022714])

HSP 1 Score: 134.42 bits (337), Expect = 1.027e-34
Identity = 91/247 (36.84%), Postives = 137/247 (55.47%), Query Frame = 2 
Query:  197 FKDMNPIFGPYFSLHD-EGYLFEAKPSLACGNRIEPPLFNT-----TKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYN-FENRIFHMN-ADESDKDIF-IPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
             +D+  +FG   S     G L E++P  AC     PP   T     T  K I LI R +C F  K++ A+ +GY+  II+N + N + +MN ++E+  D+  IPS   S      LR   +F    +   +    +  F    Y+I F G V + F ++ I   ++  +   + + NRL K  LKKIP+ KF KG D ++ CAICLD++++GDKLR+LPC+HAYH  C+DPWL + K+ CP+CK R+
Sbjct:   45 LEDLPALFGSPLSKDGVMGLLVESRPLNACAPIDPPPASPTPSDPNTTTKYIVLIRRYDCNFDIKVLHAQQAGYSAAIIHNMYSNTLLNMNYSNETIADMIDIPSVFTSYYAYQILR---SFIIPEKGAYVILKPDFSFPLTYYLIPFTGVVGLIFIVMVIILAVRCVQYRKRMRKNRLSKEQLKKIPIHKFNKG-DEYDVCAICLDEYEEGDKLRVLPCSHAYHCKCVDPWLTQTKKTCPVCKQRV 287
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Cavefish
Match: rnf13 (ring finger protein 13 [Source:NCBI gene;Acc:103029118])

HSP 1 Score: 131.724 bits (330), Expect = 5.839e-34
Identity = 86/229 (37.55%), Postives = 137/229 (59.83%), Query Frame = 2 
Query:  245 EGYLFEAKPSLACGNRIEPPLFNTTKRK----LIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            +G+L  A+P  AC   IEPP   T  R+     I LI+R +C F  K++ A+ +GY   I++N + + +  M +++ D  K I IPS  +     N L++++T+ +     V+  F       + Y+I FL  V I   LI +    K  +D ++ + +RLRK  LKK+P+ K+ KG D ++ CAICLD++++G+KLR+LPC+HAYH  C+DPWL K K+ CP+CK ++
Sbjct:   65 KGFLVGARPENAC-EPIEPP--PTKGRENSSTFIVLIKRFDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIDIVKQIDIPSVFIGEDAANALKEEYTYEKGGHVIVMPDF---SLPLEYYLIPFLIIVGICLILIVVFMITKFVQDRHRARRSRLRKDQLKKLPIHKYKKG-DVYDVCAICLDEYEEGEKLRVLPCSHAYHCKCVDPWLTKTKKTCPVCKQKV 286
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Cavefish
Match: rnf150a (ring finger protein 150 [Source:NCBI gene;Acc:103037093])

HSP 1 Score: 84.3445 bits (207), Expect = 2.937e-17
Identity = 64/225 (28.44%), Postives = 102/225 (45.33%), Query Frame = 2 
Query:  278 ACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNF----ENRIFHMNADESDK--DIFIP---SRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEG-FDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKG----RDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            AC +    P+    +   IALI RGNCT+  KI +A     + V+I+N      N    M    +     I IP    R ++++    +      T   +N   +       F S S+I++ +  ++   F     F     RD  +R+     K  + K+ ++   KG       F+ CA+C++ +K  D +RILPC H +H NC+DPW L+  R CP+CK  I
Sbjct:   90 ACDSGTRFPVSREHQGPWIALIARGNCTYREKIRLAASLNASAVVIFNVGSSNSNETITMPHQGTGDIVAIMIPEPKGREIAALLEKNVSVIMHITIGTRNLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYASARDRNQRRLGDAAKKAISKLQVRTIRKGDKETESEFDNCAVCIETYKPNDVVRILPCRHVFHKNCVDPW-LQDHRTCPMCKMNI 313
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Cavefish
Match: rnf150a (ring finger protein 150 [Source:NCBI gene;Acc:103037093])

HSP 1 Score: 83.9593 bits (206), Expect = 2.951e-17
Identity = 64/225 (28.44%), Postives = 102/225 (45.33%), Query Frame = 2 
Query:  278 ACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNF----ENRIFHMNADESDK--DIFIP---SRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEG-FDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKG----RDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            AC +    P+    +   IALI RGNCT+  KI +A     + V+I+N      N    M    +     I IP    R ++++    +      T   +N   +       F S S+I++ +  ++   F     F     RD  +R+     K  + K+ ++   KG       F+ CA+C++ +K  D +RILPC H +H NC+DPW L+  R CP+CK  I
Sbjct:   90 ACDSGTRFPVSREHQGPWIALIARGNCTYREKIRLAASLNASAVVIFNVGSSNSNETITMPHQGTGDIVAIMIPEPKGREIAALLEKNVSVIMHITIGTRNLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYASARDRNQRRLGDAAKKAISKLQVRTIRKGDKETESEFDNCAVCIETYKPNDVVRILPCRHVFHKNCVDPW-LQDHRTCPMCKMNI 313
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Cavefish
Match: si:dkeyp-86f7.4 (RING finger protein 148-like [Source:NCBI gene;Acc:103037493])

HSP 1 Score: 81.6481 bits (200), Expect = 1.514e-16
Identity = 62/219 (28.31%), Postives = 101/219 (46.12%), Query Frame = 2 
Query:  308 FNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENR------IFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGR-------DPF-----ETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            F+  KR  IALI+RGNC++  KI  A     + V+IYN++        + H   DE      I +  +S+  G  +  Q         ++      +   S +++ +          +I   F I + +  Y+ +  R ++  +KK+  +   K +       DP       TCA+C+D FK GD +  LPC+H +H  CI+PWLL+    CP+CKY I
Sbjct:   90 FSVKKRPWIALIKRGNCSYADKIRAALRKKASAVVIYNYDGAGNATTPMSHPGVDE------IVAITISNNLGKEISSQVESGTMAYMYIEVGNRFKSMGSPTWVYIMSFTFFGITAVILGYFIIVVIKRIYRNRQLRRQQREMKKVAERAISKLQVRTLRRNDPEVEAEENTCAVCIDPFKRGDIVTNLPCSHLFHKTCIEPWLLEH-HTCPMCKYDI 301
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003771.1 (pep scaffold:Pmarinus_7.0:GL488469:4:5386:-1 gene:ENSPMAG00000003449.1 transcript:ENSPMAT00000003771.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.2629 bits (199), Expect = 2.644e-19
Identity = 26/51 (50.98%), Postives = 44/51 (86.27%), Query Frame = 2 
Query:  758 DPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            D ++ CAICL+++++G++LR+LPC HA+H  C+DPWL +Q++NCP+CK ++
Sbjct:    2 DSYDVCAICLEEYEEGERLRVLPCAHAFHCKCVDPWLTQQRKNCPVCKRKV 52
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Sea Lamprey
Match: rnf150a (ring finger protein 150a [Source:ZFIN;Acc:ZDB-GENE-060213-1])

HSP 1 Score: 82.0333 bits (201), Expect = 1.560e-17
Identity = 61/214 (28.50%), Postives = 98/214 (45.79%), Query Frame = 2 
Query:  332 IALIERGNCTFGHKIIVAELSGYTGVIIYN---FENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEG--------------FDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDP----FETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            +ALI + NC+   KI+ A     + V+I N     N    M+  ++ + + I   MV+ + G   R+  +  E  +N  +      G              F S S+I++ +  ++   F           RD ++R+     K  + K+PLK   KG       F+ CA+C++ +K  D +RILPC H +H  C+DPWLL   R CP+CK  I
Sbjct:  129 VALISKENCSVRDKILRAMAYNASAVVIANGPGTGNETTAMHHKDTGEIVVI---MVTELKG---REMMSLLE--RNITVMVHVTVGTRNVQKFVSRTSVVFVSISFIVLMIISLAWLVFYYVQRLRYASARDRHQRRLGDAAKKAMTKLPLKTIKKGDQETEPDFDNCAVCIEGYKPNDVVRILPCKHLFHKACVDPWLLDH-RTCPMCKLNI 333
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003380.1 (pep scaffold:Pmarinus_7.0:GL476517:4028:13530:1 gene:ENSPMAG00000003092.1 transcript:ENSPMAT00000003380.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.2326 bits (147), Expect = 4.229e-12
Identity = 27/55 (49.09%), Postives = 38/55 (69.09%), Query Frame = 2 
Query:  758 DPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPG 922
            D +ETCA+CL+DF   DKL I PC HA+H  C+  W L+ +++CP+C   I +PG
Sbjct:   28 DCYETCAVCLEDFTLKDKLGICPCRHAFHRKCLVRW-LEIRKSCPMCITPILLPG 81
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Sea Lamprey
Match: si:ch1073-392o20.1 (ring finger protein 122 [Source:HGNC Symbol;Acc:HGNC:21147])

HSP 1 Score: 54.299 bits (129), Expect = 3.671e-10
Identity = 20/44 (45.45%), Postives = 32/44 (72.73%), Query Frame = 2 
Query:  767 ETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPIC 898
            +TCA+CL+DF++ D+L + PC HA+H  C+  W L+ +  CP+C
Sbjct:   15 QTCAVCLEDFREKDELAVCPCKHAFHRKCLVKW-LEIRNACPMC 57
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Sea Lamprey
Match: rnf126 (ring finger protein 126 [Source:ZFIN;Acc:ZDB-GENE-070209-292])

HSP 1 Score: 56.9954 bits (136), Expect = 2.290e-9
Identity = 21/47 (44.68%), Postives = 31/47 (65.96%), Query Frame = 2 
Query:  773 CAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIK 913
            C++C +DF +G+K R LPC H YH +CI PW L+    CP+C+  + 
Sbjct:  225 CSVCKEDFDEGEKARQLPCKHIYHTDCIIPW-LEMHDTCPVCRTSLS 270
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Nematostella
Match: EDO36379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIX4])

HSP 1 Score: 115.546 bits (288), Expect = 8.081e-29
Identity = 94/312 (30.13%), Postives = 144/312 (46.15%), Query Frame = 2 
Query:  191 YGFKDMNPIFGPYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNF-ENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTE--SRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNH----------------------------AYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXX-TPQTVPQPLASEHTPLINTSQPSNST 1030
            YG  D    FG   S   +G+   A P  AC      P+ + +      +IE G C+FG K  +A+   Y   IIY+   ++I  M +DE  +       +V+   G    ++ T  +  +R N V+       ++ + YI+ F   V I F L+G+    +  R   +++ NRL   +L+KIP KKF KG + ++ CAICLD++K+GDKLRILPC+H                            AYH  C+DPWL + KR CP+CK  ++   +            Q   +   SE TPLI  S  +++ 
Sbjct:   50 YGLAD----FGQLLSRSIQGFGVLASPKNACSTV--QPIKSKSNMFWFLVIEDGGCSFGEKAYMAQKGEYDAAIIYSLTSDKIIDMESDEYGRK---ADDIVAIHIGKTAAKELTRIDVLARNNIVINPQYLLLWNLEVYILPFAVIVGICFVLMGLFMISRYYRHYLEKRRNRLSLTNLRKIPTKKFKKGDEYYDVCAICLDEYKEGDKLRILPCDHGDEYYDVCAICLDEYKEGDKLRILPCDHAYHCKCVDPWLTEGKRTCPVCKRPVETSKKKKQGIQGSADAEQGHHEHEPSETTPLIRPSTQTSTA 352
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Nematostella
Match: EDO41758 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3E3])

HSP 1 Score: 80.1073 bits (196), Expect = 6.631e-17
Identity = 61/211 (28.91%), Postives = 99/211 (46.92%), Query Frame = 2 
Query:  323 RKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENR---IFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEG-----------FDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDP-FETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            R  IAL+ RG+C F  KI  A     T +IIY+ ++    I  +NA   +      ++ +     ++LR       SR  +       +            F S S+I++ +  ++   F     F     RD  +++ +   K  + K+P +   K  +   ++C +CLD +K G+ +RILPCNH YH  CIDPWL++  R CP+CK  I
Sbjct:   66 RPWIALVRRGSCRFNTKIANAFKYNATAIIIYDSQDSDDVITMLNAGAPNLVSVSITKRLGEYLADKLRNN-----SRAIYAEILVGEKHSKWRVNPTSVLFVSVSFIVLMVISLAWLVFYYVQRFRYVHARDKTEKRLSSAAKKAIAKLPTRTVKKDEEEEIDSCPVCLDGYKSGEVIRILPCNHEYHKLCIDPWLVEH-RTCPMCKLNI 270
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Nematostella
Match: EDO40583 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6T4])

HSP 1 Score: 56.225 bits (134), Expect = 1.043e-9
Identity = 28/77 (36.36%), Postives = 41/77 (53.25%), Query Frame = 2 
Query:  668 LCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPIC 898
            L  +   R A RL    ++ +P+ ++   +     C IC+ DF  GD +R LPC H YH +CID WL++    CP C
Sbjct:   53 LSEEQQIRLAQRLGL--IQHLPVGEYDGSKGKKRECVICMYDFMVGDPIRFLPCMHIYHKDCIDDWLVR-SFTCPSC 126
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Nematostella
Match: EDO29210 (pep supercontig:ASM20922v1:NEMVEscaffold_1403:17060:20569:-1 gene:NEMVEDRAFT_v1g145359 transcript:EDO29210 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.5286 bits (127), Expect = 3.811e-9
Identity = 18/47 (38.30%), Postives = 33/47 (70.21%), Query Frame = 2 
Query:  770 TCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            +C ICL D++ G+  + +PC+H +H  CI PW L++  +CP+C++ +
Sbjct:   28 SCPICLGDYEKGESTKQMPCDHLFHPGCILPW-LEKTNSCPVCRHEL 73
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Nematostella
Match: EDO45479 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSU5])

HSP 1 Score: 53.1434 bits (126), Expect = 5.623e-9
Identity = 18/47 (38.30%), Postives = 33/47 (70.21%), Query Frame = 2 
Query:  770 TCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            +C ICL D++ G+  + +PC+H +H  CI PW L++  +CP+C++ +
Sbjct:   28 SCPICLGDYEKGESTKQMPCDHLFHPGCILPW-LEKTNSCPVCRHEL 73
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Medaka
Match: rnf13 (ring finger protein 13 [Source:NCBI gene;Acc:101161477])

HSP 1 Score: 149.828 bits (377), Expect = 9.368e-41
Identity = 104/277 (37.55%), Postives = 160/277 (57.76%), Query Frame = 2 
Query:  197 FKDMNPIFGPYFSLHDEG---YLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFE-NRIFHMNADESD--KDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLINT 1009
            F DM   FG  F L  +G   +L  A+P  AC   IEPP  +      I LI+R +C F  K++ A+ +GY   I++N + + +  M +++ D  K I IPS  VSS   N L+  + + +     ++  F       + Y++ FL  V+I   LI +    K  +D  K   +RLRK  LKK+P+ K+ KG D ++ CAICLD++++GDKLR+LPC+HAYH+ C+DPWL K K+ CP+CK ++ +P +  DSDS + +P+   +   SE TPL+ +
Sbjct:   48 FDDMPARFG--FRLPSDGLKGFLIGARPENAC-EPIEPPPSDNLTGAFIVLIKRFDCNFDVKVLNAQKAGYKAAIVHNVDSDDLISMGSNDLDVVKQIVIPSVFVSSEAANTLKGDYMYDKGGHVVLIPDF---SLPLEYYLLPFLLIVAICLILIAVFMITKAVQDCRKAWKSRLRKDQLKKLPIHKYQKG-DSYDVCAICLDEYEEGDKLRVLPCSHAYHSKCVDPWLTKTKKTCPVCKQKV-VPSQ-GDSDSEESSPEDNEE--VSESTPLLRS 313
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Medaka
Match: rnf167 (E3 ubiquitin-protein ligase RNF167 [Source:NCBI gene;Acc:101167225])

HSP 1 Score: 134.42 bits (337), Expect = 6.893e-35
Identity = 91/255 (35.69%), Postives = 133/255 (52.16%), Query Frame = 2 
Query:  179 NESYYGFKDMNPIFG---PYFSLHDEGYLFEAKPSLACGNRIEPP----LFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYN-FENRIFHMNA--DESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKR-QANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            N S   F+D+  +FG   P   L   G L  ++P+  C     PP     F+    K +ALI+R +C F  K+  A+ +GY+  II+N + + + +MN   D   + I IPS   S      LR  + F E   + V      E     SY ++    V     ++     I  C    KR + NRL K  LK+IP  +F KG D ++ CAICLD++++GDKLR+LPC+HAYH  C+DPWL + K+ CP+CK R+
Sbjct:   39 NMSSMLFEDLPALFGARVPTGGL--TGLLVPSQPANGCAAMNPPPPLPSSFDANTTKFVALIKRYDCNFDIKVFHAQQAGYSAAIIHNMYSDTLLNMNYSNDTIAEQIEIPSVFTSYYASEILRT-YLFPE---HVVYVTLKPEFAFPLSYYLIPFTGVVGMIIIVMCVIMIIRCVQYRKRIRKNRLTKEQLKRIPTHRFTKGDD-YDVCAICLDEYEEGDKLRVLPCSHAYHCKCVDPWLTQTKKTCPVCKQRV 286
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Medaka
Match: rnf167 (E3 ubiquitin-protein ligase RNF167 [Source:NCBI gene;Acc:101167225])

HSP 1 Score: 134.42 bits (337), Expect = 7.093e-35
Identity = 91/255 (35.69%), Postives = 133/255 (52.16%), Query Frame = 2 
Query:  179 NESYYGFKDMNPIFG---PYFSLHDEGYLFEAKPSLACGNRIEPP----LFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYN-FENRIFHMNA--DESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKR-QANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            N S   F+D+  +FG   P   L   G L  ++P+  C     PP     F+    K +ALI+R +C F  K+  A+ +GY+  II+N + + + +MN   D   + I IPS   S      LR  + F E   + V      E     SY ++    V     ++     I  C    KR + NRL K  LK+IP  +F KG D ++ CAICLD++++GDKLR+LPC+HAYH  C+DPWL + K+ CP+CK R+
Sbjct:   39 NMSSMLFEDLPALFGARVPTGGL--TGLLVPSQPANGCAAMNPPPPLPSSFDANTTKFVALIKRYDCNFDIKVFHAQQAGYSAAIIHNMYSDTLLNMNYSNDTIAEQIEIPSVFTSYYASEILRT-YLFPE---HVVYVTLKPEFAFPLSYYLIPFTGVVGMIIIVMCVIMIIRCVQYRKRIRKNRLTKEQLKRIPTHRFTKGDD-YDVCAICLDEYEEGDKLRVLPCSHAYHCKCVDPWLTQTKKTCPVCKQRV 286
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Medaka
Match: si:dkeyp-86f7.4 (E3 ubiquitin-protein ligase RNF128 [Source:NCBI gene;Acc:101174167])

HSP 1 Score: 85.8853 bits (211), Expect = 5.544e-18
Identity = 62/214 (28.97%), Postives = 100/214 (46.73%), Query Frame = 2 
Query:  332 IALIERGNCTFGHKIIVAELSGYTGVIIYNFE---NRIFHMNADESDKDIFIPSRMVSSVTGN---RLRQQFTFTE-----------SRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFET----CAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            IAL++RGNCTF  KI  A+  G   V++YN E   N   HM   E+D  + I   MV ++ G+   RL Q  T  +               + L+F     F   +  I +  F+S               R   ++  N  +K  + ++ ++   +G +   +    CA+C++ +K GD + +L C+H +H  CI+PWLL  +R CP+CK  I
Sbjct:   91 IALVKRGNCTFSEKINAAKRQGAAAVVVYNVEGSGNSTTHMAHAEADGIVAI---MVGNIQGSEIVRLVQNGTEVQLLIEVGSPHGPWMDTYWLYFLSIAFFIVTAASIAYFVFISANRLYNMNRQ-----RRTERKMKNEAKKA-IGRLQVRTLRRGDEEITSDSHLCAVCIESYKQGDVVTVLTCDHIFHKACIEPWLL-DRRTCPMCKSDI 294
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Medaka
Match: rnf130 (ring finger protein 130 [Source:NCBI gene;Acc:101165289])

HSP 1 Score: 83.9593 bits (206), Expect = 3.247e-17
Identity = 72/248 (29.03%), Postives = 103/248 (41.53%), Query Frame = 2 
Query:  332 IALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMNADESDKDIFIPSRMVSSVTGN----RLRQQFTFTESR--QNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKG---RDP-FETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI-KIPGRXXX-----XXXXXXTPQTVPQPLASEHTPLINTSQPSNS 1027
            +AL++RGNCTF  KI+ A     T V+IYN           E   +I   + M++   G      L + FT   S      + +F     F S                           RD  +R+     K  + K+  +   KG    DP F  CA+C++ ++  D +RILPC H +H  C+DPW L +   CP+CK  I K  G         S  +D     V QP  S+  PL ++ QPS S
Sbjct:  112 VALLQRGNCTFKEKILKAAAYNATAVLIYNNSTEKTVKMGHEGTGEIV--AVMITDAYGKEILAHLERNFTVLVSVVVAWLIFYFIQKIRFSS--------------------------ARDRSQRRLGDAAKKAIGKLTTRTVKKGDKETDPDFNHCAVCIEAYQLNDVVRILPCKHVFHKVCVDPW-LNEHCTCPMCKLNILKALGIMTTLPCMDSVVLDVERLGVSQPSGSQRAPLSDSMQPSIS 330
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Planmine SMEST
Match: SMESG000013169.1 (SMESG000013169.1)

HSP 1 Score: 698.353 bits (1801), Expect = 0.000e+0
Identity = 374/376 (99.47%), Postives = 375/376 (99.73%), Query Frame = 2 
Query:  104 MKSNILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLINTSQPSNSTRYLINGEREINFIPERNPTSPCCYDNLTCEFIESNVASSPVPPNDRPLSSSILHSDENKQTDLSKIV 1231
            MKSNILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHDEGYLFEAKPSLACGN IEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFEN+IFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYIIVFLGFVSIGFFLIGIGFGIKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRDDDSDSVDDTPQTVPQPLASEHTPLINTSQPSNSTRYLINGEREINFIPERNPTSPCCYDNLTCEFIESNVASSPVPPNDRPLSSSILHSDENKQTDLSKIV
Sbjct:    1 MKSNILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHDEGYLFEAKPSLACGNSIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENKIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYIIVFLGFVSIGFFLIGIGFGIKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRDDDSDSVDDTPQTVPQPLASEHTPLINTSQPSNSTRYLINGEREINFIPERNPTSPCCYDNLTCEFIESNVASSPVPPNDRPLSSSILHSDENKQTDLSKIV 376
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Planmine SMEST
Match: SMESG000013169.1 (SMESG000013169.1)

HSP 1 Score: 657.522 bits (1695), Expect = 0.000e+0
Identity = 359/376 (95.48%), Postives = 360/376 (95.74%), Query Frame = 2 
Query:  104 MKSNILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLINTSQPSNSTRYLINGEREINFIPERNPTSPCCYDNLTCEFIESNVASSPVPPNDRPLSSSILHSDENKQTDLSKIV 1231
            MKSNILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHDEGYLFEAKPSLACGN IEPPLFNTTKRKLIALIERG               YTGVIIYNFEN+IFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYIIVFLGFVSIGFFLIGIGFGIKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRDDDSDSVDDTPQTVPQPLASEHTPLINTSQPSNSTRYLINGEREINFIPERNPTSPCCYDNLTCEFIESNVASSPVPPNDRPLSSSILHSDENKQTDLSKIV
Sbjct:    1 MKSNILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHDEGYLFEAKPSLACGNSIEPPLFNTTKRKLIALIERG---------------YTGVIIYNFENKIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYIIVFLGFVSIGFFLIGIGFGIKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRDDDSDSVDDTPQTVPQPLASEHTPLINTSQPSNSTRYLINGEREINFIPERNPTSPCCYDNLTCEFIESNVASSPVPPNDRPLSSSILHSDENKQTDLSKIV 361
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Planmine SMEST
Match: SMESG000013169.1 (SMESG000013169.1)

HSP 1 Score: 629.402 bits (1622), Expect = 0.000e+0
Identity = 340/342 (99.42%), Postives = 341/342 (99.71%), Query Frame = 2 
Query:  206 MNPIFGPYFSLHDEGYLFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYXXXXXXXXXXXXXXXXXXXXXKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRXXXXXXXXXTPQTVPQPLASEHTPLINTSQPSNSTRYLINGEREINFIPERNPTSPCCYDNLTCEFIESNVASSPVPPNDRPLSSSILHSDENKQTDLSKIV 1231
            MNPIFGPYFSLHDEGYLFEAKPSLACGN IEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFEN+IFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYIIVFLGFVSIGFFLIGIGFGIKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRDDDSDSVDDTPQTVPQPLASEHTPLINTSQPSNSTRYLINGEREINFIPERNPTSPCCYDNLTCEFIESNVASSPVPPNDRPLSSSILHSDENKQTDLSKIV
Sbjct:    1 MNPIFGPYFSLHDEGYLFEAKPSLACGNSIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYTGVIIYNFENKIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQNFVLFFFDNEGFDSQSYIIVFLGFVSIGFFLIGIGFGIKLCRDAYKRQANRLRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIPGRDDDSDSVDDTPQTVPQPLASEHTPLINTSQPSNSTRYLINGEREINFIPERNPTSPCCYDNLTCEFIESNVASSPVPPNDRPLSSSILHSDENKQTDLSKIV 342
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Planmine SMEST
Match: SMESG000026513.1 (SMESG000026513.1)

HSP 1 Score: 78.1814 bits (191), Expect = 3.250e-15
Identity = 36/83 (43.37%), Postives = 54/83 (65.06%), Query Frame = 2 
Query:  674 RDAYKRQANRLRKCHLKKIPLKKFVKG---RDP-FETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            ++ + R+   + K  + KIP+K   +G    DP  + CAIC++ +K  D +RILPC H +H +CIDPWLL+Q R+CP+CK  I
Sbjct:  320 KEQFSRRLAHMAKKAVAKIPVKTLKQGDRETDPDLDNCAICIECYKPSDTVRILPCKHYFHKSCIDPWLLEQ-RSCPMCKLNI 401
[Close]
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Planmine SMEST
Match: SMESG000026513.1 (SMESG000026513.1)

HSP 1 Score: 78.1814 bits (191), Expect = 3.523e-15
Identity = 36/83 (43.37%), Postives = 54/83 (65.06%), Query Frame = 2 
Query:  674 RDAYKRQANRLRKCHLKKIPLKKFVKG---RDP-FETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRI 910
            ++ + R+   + K  + KIP+K   +G    DP  + CAIC++ +K  D +RILPC H +H +CIDPWLL+Q R+CP+CK  I
Sbjct:  326 KEQFSRRLAHMAKKAVAKIPVKTLKQGDRETDPDLDNCAICIECYKPSDTVRILPCKHYFHKSCIDPWLLEQ-RSCPMCKLNI 407
The following BLAST results are available for this feature:
BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RNF131.058e-3834.27ring finger protein 13 [Source:HGNC Symbol;Acc:HGN... [more]
RNF131.058e-3834.27ring finger protein 13 [Source:HGNC Symbol;Acc:HGN... [more]
RNF1671.317e-3834.86ring finger protein 167 [Source:HGNC Symbol;Acc:HG... [more]
RNF1671.926e-3833.12ring finger protein 167 [Source:HGNC Symbol;Acc:HG... [more]
RNF1671.926e-3833.12ring finger protein 167 [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
C18B12.43.525e-2431.47pep chromosome:WBcel235:X:15036662:15040602:-1 gen... [more]
H10E21.53.017e-1244.16pep chromosome:WBcel235:III:20531:23962:-1 gene:WB... [more]
plr-11.484e-1147.92Probable E3 ubiquitin-protein ligase plr-1 [Sourc... [more]
C01G6.46.075e-1143.28pep chromosome:WBcel235:II:9271265:9273042:-1 gene... [more]
toe-41.005e-841.67Target Of ERK kinase MPK-1 [Source:UniProtKB/TrEM... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gzl6.914e-3035.48gene:FBgn0037442 transcript:FBtr0081721[more]
gzl6.914e-3035.48gene:FBgn0037442 transcript:FBtr0081722[more]
gzl6.914e-3035.48gene:FBgn0037442 transcript:FBtr0081720[more]
gzl6.914e-3035.48gene:FBgn0037442 transcript:FBtr0113198[more]
gol9.070e-1531.10gene:FBgn0004919 transcript:FBtr0300178[more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf1674.485e-3434.04ring finger protein 167 [Source:ZFIN;Acc:ZDB-GENE-... [more]
rnf135.569e-3432.96ring finger protein 13 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
rnf131.570e-2033.33ring finger protein 13 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
rnf150a7.799e-1727.87ring finger protein 150a [Source:ZFIN;Acc:ZDB-GENE... [more]
rnf1307.800e-1428.10ring finger protein 130 [Source:ZFIN;Acc:ZDB-GENE-... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf132.378e-3538.22ring finger protein 13 [Source:NCBI gene;Acc:49337... [more]
rnf133.598e-3538.05ring finger protein 13 [Source:NCBI gene;Acc:49337... [more]
rnf133.721e-3538.05ring finger protein 13 [Source:NCBI gene;Acc:49337... [more]
RNF1679.081e-3435.71ring finger protein 167 [Source:NCBI gene;Acc:1003... [more]
rnf1301.128e-1629.03ring finger protein 130 [Source:NCBI gene;Acc:1001... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rnf1672.720e-4135.45ring finger protein 167 [Source:MGI Symbol;Acc:MGI... [more]
Rnf132.819e-4034.74ring finger protein 13 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf131.859e-2431.85ring finger protein 13 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf134.139e-2433.08ring finger protein 13 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf1285.969e-1830.84ring finger protein 128 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q91XF4|RN167_MOUSE1.903e-4035.45E3 ubiquitin-protein ligase RNF167 OS=Mus musculus... [more]
sp|O54965|RNF13_MOUSE1.972e-3934.74E3 ubiquitin-protein ligase RNF13 OS=Mus musculus ... [more]
sp|Q66HG0|RNF13_RAT2.013e-3934.74E3 ubiquitin-protein ligase RNF13 OS=Rattus norveg... [more]
sp|Q0VD51|RNF13_BOVIN6.288e-3934.58E3 ubiquitin-protein ligase RNF13 OS=Bos taurus OX... [more]
sp|Q5RCV8|RNF13_PONAB5.079e-3834.27E3 ubiquitin-protein ligase RNF13 OS=Pongo abelii ... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A433ST641.565e-4133.45RING-type domain-containing protein OS=Elysia chlo... [more]
A0A0B7AC543.723e-4138.75RING-type domain-containing protein (Fragment) OS=... [more]
A0A0B7ACF44.426e-4138.75RING-type domain-containing protein OS=Arion vulga... [more]
A0A4S2KYW34.903e-4134.15RING-type domain-containing protein OS=Opisthorchi... [more]
A0A4S2KY999.038e-4134.15RING-type domain-containing protein OS=Opisthorchi... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf1671.027e-3436.84ring finger protein 167 [Source:NCBI gene;Acc:1030... [more]
rnf135.839e-3437.55ring finger protein 13 [Source:NCBI gene;Acc:10302... [more]
rnf150a2.937e-1728.44ring finger protein 150 [Source:NCBI gene;Acc:1030... [more]
rnf150a2.951e-1728.44ring finger protein 150 [Source:NCBI gene;Acc:1030... [more]
si:dkeyp-86f7.41.514e-1628.31RING finger protein 148-like [Source:NCBI gene;Acc... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000003771.12.644e-1950.98pep scaffold:Pmarinus_7.0:GL488469:4:5386:-1 gene:... [more]
rnf150a1.560e-1728.50ring finger protein 150a [Source:ZFIN;Acc:ZDB-GENE... [more]
ENSPMAT00000003380.14.229e-1249.09pep scaffold:Pmarinus_7.0:GL476517:4028:13530:1 ge... [more]
si:ch1073-392o20.13.671e-1045.45ring finger protein 122 [Source:HGNC Symbol;Acc:HG... [more]
rnf1262.290e-944.68ring finger protein 126 [Source:ZFIN;Acc:ZDB-GENE-... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO363798.081e-2930.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO417586.631e-1728.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO405831.043e-936.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO292103.811e-938.30pep supercontig:ASM20922v1:NEMVEscaffold_1403:1706... [more]
EDO454795.623e-938.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf139.368e-4137.55ring finger protein 13 [Source:NCBI gene;Acc:10116... [more]
rnf1676.893e-3535.69E3 ubiquitin-protein ligase RNF167 [Source:NCBI ge... [more]
rnf1677.093e-3535.69E3 ubiquitin-protein ligase RNF167 [Source:NCBI ge... [more]
si:dkeyp-86f7.45.544e-1828.97E3 ubiquitin-protein ligase RNF128 [Source:NCBI ge... [more]
rnf1303.247e-1729.03ring finger protein 130 [Source:NCBI gene;Acc:1011... [more]
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BLAST of E3 ubiquitin-protein ligase RNF13 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000013169.10.000e+099.47SMESG000013169.1[more]
SMESG000013169.10.000e+095.48SMESG000013169.1[more]
SMESG000013169.10.000e+099.42SMESG000013169.1[more]
SMESG000026513.13.250e-1543.37SMESG000026513.1[more]
SMESG000026513.13.523e-1543.37SMESG000026513.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024336 ID=SMED30024336|Name=E3 ubiquitin-protein ligase RNF13|organism=Schmidtea mediterranea sexual|type=transcript|length=1324bp
TCTTCCGATCTGAAAATCTTTGAATAATGTTAATTTTTATTTAATATTTG
AGATTATTTATTTATGTAGTGAATAAAGTTTCTTTTCTATAAAAATCTTG
CAAATGAAATCAAATATTCTATTAGTTGTATTGTTTGATATTGTTTTTTG
CGACTTCAAAATTGTCGATACTGATTTAAATGAAAGTTATTATGGTTTCA
AGGACATGAATCCAATTTTTGGACCATACTTTAGTTTACATGATGAAGGT
TATCTATTTGAAGCTAAACCATCGTTAGCTTGTGGAAATAGAATTGAACC
TCCGTTGTTCAATACGACGAAGAGAAAATTAATTGCTTTAATTGAACGAG
GTAATTGCACATTTGGACACAAAATTATAGTAGCCGAATTATCAGGATAT
ACTGGTGTAATTATTTACAATTTTGAAAATAGAATTTTCCATATGAATGC
AGATGAATCTGACAAGGATATTTTTATTCCATCTCGAATGGTAAGTTCAG
TAACTGGTAATCGATTAAGACAGCAGTTCACATTCACAGAAAGTCGTCAA
AATTTTGTTTTATTTTTCTTCGATAATGAGGGGTTTGATTCACAATCATA
TATAATTGTGTTTCTTGGATTTGTTTCCATTGGTTTTTTTCTTATTGGCA
TTGGTTTTGGCATAAAACTTTGTCGCGATGCTTACAAAAGACAAGCAAAT
AGATTAAGAAAATGCCATTTGAAAAAAATACCCCTGAAAAAGTTTGTCAA
AGGTCGTGACCCGTTTGAAACATGTGCTATATGTCTTGATGACTTCAAAG
ATGGCGATAAGTTAAGAATTTTACCTTGCAACCATGCATATCATGCAAAT
TGCATTGATCCATGGTTATTAAAACAGAAACGAAACTGTCCAATTTGTAA
ATACCGAATTAAGATACCTGGAAGAGACGATGATTCTGACAGTGTTGACG
ATACACCACAAACAGTTCCTCAACCGCTAGCTAGTGAACATACTCCACTT
ATTAATACTTCGCAACCCTCAAATTCCACCAGATATTTAATTAATGGTGA
AAGAGAAATAAATTTCATTCCAGAACGCAATCCTACATCACCGTGTTGTT
ACGATAATTTAACCTGTGAATTCATTGAATCAAATGTGGCATCATCTCCA
GTACCACCAAATGACAGGCCATTATCATCCAGTATTCTTCATTCAGACGA
AAATAAACAAACAGATCTATCAAAAATTGTTTAATAAATACTTGATACTT
TGATAAATTCATCAGAAACTCATAAACTTTTTTATTTATATGAGCTTTAA
ATTTTTAATTATAATGCCCATGCC
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protein sequence of SMED30024336-orf-1

>SMED30024336-orf-1 ID=SMED30024336-orf-1|Name=SMED30024336-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=377bp
MKSNILLVVLFDIVFCDFKIVDTDLNESYYGFKDMNPIFGPYFSLHDEGY
LFEAKPSLACGNRIEPPLFNTTKRKLIALIERGNCTFGHKIIVAELSGYT
GVIIYNFENRIFHMNADESDKDIFIPSRMVSSVTGNRLRQQFTFTESRQN
FVLFFFDNEGFDSQSYIIVFLGFVSIGFFLIGIGFGIKLCRDAYKRQANR
LRKCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANC
IDPWLLKQKRNCPICKYRIKIPGRDDDSDSVDDTPQTVPQPLASEHTPLI
NTSQPSNSTRYLINGEREINFIPERNPTSPCCYDNLTCEFIESNVASSPV
PPNDRPLSSSILHSDENKQTDLSKIV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000101muscle cell
PLANA:0000204ovary
PLANA:0000208testis
PLANA:0003001lateral region of the whole animal
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR001841Znf_RING
IPR003137PA_domain
IPR013083Znf_RING/FYVE/PHD
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0005515protein binding
GO:0004842ubiquitin-protein transferase activity
GO:0016740transferase activity
GO:0046872metal ion binding
GO:0061630ubiquitin protein ligase activity
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005637nuclear inner membrane
GO:0005654nucleoplasm
GO:0005737cytoplasm
GO:0005764lysosome
GO:0005765lysosomal membrane
GO:0005768endosome
GO:0005829cytosol
GO:0016020membrane
GO:0016021integral component of membrane
GO:0031902late endosome membrane
GO:0043231intracellular membrane-bounded organelle
Vocabulary: biological process
TermDefinition
GO:0016567protein ubiquitination
GO:0051865protein autoubiquitination
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001841Zinc finger, RING-typeSMARTSM00184ring_2coord: 224..265
e-value: 6.8E-10
score: 48.9
IPR001841Zinc finger, RING-typePFAMPF13639zf-RING_2coord: 223..266
e-value: 2.9E-14
score: 53.1
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 224..266
score: 13.168
IPR003137PA domainPFAMPF02225PAcoord: 76..138
e-value: 3.8E-7
score: 30.0
NoneNo IPR availableGENE3DG3DSA:3.50.30.30coord: 31..149
e-value: 7.6E-18
score: 66.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 347..366
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 283..297
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 347..376
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 276..297
NoneNo IPR availablePANTHERPTHR22765RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAININGcoord: 48..303
NoneNo IPR availablePANTHERPTHR22765:SF34E3 UBIQUITIN-PROTEIN LIGASE RNF13coord: 48..303
NoneNo IPR availableCDDcd16665RING-H2_RNF13_likecoord: 222..266
e-value: 4.56041E-26
score: 96.7079
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..16
score: 0.617
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 210..272
NoneNo IPR availableSUPERFAMILYSSF52025PA domaincoord: 77..120
NoneNo IPR availableTMHMMTMhelixcoord: 165..187
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 196..274
e-value: 1.1E-19
score: 71.4