SMED30024248
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024248 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Alignments
SMED30024248 aligns in the following genomic locations:
Homology
BLAST of SMED30024248 vs. Ensembl Human
Match: LRRTM2 (leucine rich repeat transmembrane neuronal 2 [Source:HGNC Symbol;Acc:HGNC:19409]) HSP 1 Score: 65.855 bits (159), Expect = 8.446e-11 Identity = 46/123 (37.40%), Postives = 69/123 (56.10%), Query Frame = 2
Query: 641 LKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
L++ + ++ + F + QL L + NQIS + +F+GL L L LSSN+ F F ++ NL LDLSFN++++L ++F GL KLQ LHL +N L I F SL +L+L
Sbjct: 68 LRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI--FYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDL 188 HSP 2 Score: 55.4546 bits (132), Expect = 1.557e-7 Identity = 58/187 (31.02%), Postives = 92/187 (49.20%), Query Frame = 2
Query: 566 KIENIKLDSWSSEYLSVCQSVEIIILKN--LQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLC-LNPIKANLIKIFISADSIQCVEM 1117
+I +K D++ Y + E+I+ N L N F +N L+ L + FNQ+S + F GL+ L L L SN T F + +L LDLS NR+ +L+ F GL+KL++LHL +N L I+ F L SL L L N + +L C + L K+ ++ + I+ +++
Sbjct: 96 QISTVKEDAFQGLY----KLKELILSSNKIFYLPNTTFTQLIN---LQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLR--TIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNK---ISNLTCGMEWTWGTLEKLDLTGNEIKAIDL 270 HSP 3 Score: 53.9138 bits (128), Expect = 5.220e-7 Identity = 45/159 (28.30%), Postives = 75/159 (47.17%), Query Frame = 2
Query: 542 GLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
GL KL+ L + + L + C+S+E + L +L ++ F +L+ L + NQ+++I+ F L L L L N+ + T G L KLDL+ N I A+ + +F + L+ L ++NN L +D+ L SL + L N
Sbjct: 155 GLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEW--TWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGN 311
BLAST of SMED30024248 vs. Ensembl Human
Match: LRRTM3 (leucine rich repeat transmembrane neuronal 3 [Source:HGNC Symbol;Acc:HGNC:19410]) HSP 1 Score: 65.855 bits (159), Expect = 9.683e-11 Identity = 45/121 (37.19%), Postives = 65/121 (53.72%), Query Frame = 2
Query: 656 LENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L+ + + F QL L + N IS I +F G++ L L LSSN+ +F N FR + NL LDLS+N++ +L + F GL KL LHL +N L I F+ +L L+L +N
Sbjct: 73 LQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNT--FRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYN 191 HSP 2 Score: 61.2326 bits (147), Expect = 2.586e-9 Identity = 52/201 (25.87%), Postives = 93/201 (46.27%), Query Frame = 2
Query: 530 NFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLN-------PIKANLIKIFISADSIQCV 1111
N GLN+L L +++ + + + + ++ +IL + ++ F L+ L + +NQ+ + F+GL+ L L L SN T F++ NL LDL +NRI +L+ +F G+++L++LHL +N ++ F L+SL L L N ++ + + N I+ F QCV
Sbjct: 79 NQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLR--TIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCV 277
BLAST of SMED30024248 vs. Ensembl Human
Match: LINGO2 (leucine rich repeat and Ig domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21207]) HSP 1 Score: 65.4698 bits (158), Expect = 1.428e-10 Identity = 52/161 (32.30%), Postives = 81/161 (50.31%), Query Frame = 2
Query: 536 LSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
SGL L+QL +E L + +E LS +S+ + LK+L + N+ AF F LK L I + + + ++ L L SLS T F+ + L L+LS+N I+ + MF L++LQ+LH+ L I+ +F+GL L LN+ N
Sbjct: 173 FSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPL--LDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQN 331
BLAST of SMED30024248 vs. Ensembl Human
Match: LINGO2 (leucine rich repeat and Ig domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21207]) HSP 1 Score: 65.4698 bits (158), Expect = 1.428e-10 Identity = 52/161 (32.30%), Postives = 81/161 (50.31%), Query Frame = 2
Query: 536 LSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
SGL L+QL +E L + +E LS +S+ + LK+L + N+ AF F LK L I + + + ++ L L SLS T F+ + L L+LS+N I+ + MF L++LQ+LH+ L I+ +F+GL L LN+ N
Sbjct: 173 FSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPL--LDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQN 331
BLAST of SMED30024248 vs. Ensembl Human
Match: LINGO2 (leucine rich repeat and Ig domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21207]) HSP 1 Score: 65.4698 bits (158), Expect = 1.428e-10 Identity = 52/161 (32.30%), Postives = 81/161 (50.31%), Query Frame = 2
Query: 536 LSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
SGL L+QL +E L + +E LS +S+ + LK+L + N+ AF F LK L I + + + ++ L L SLS T F+ + L L+LS+N I+ + MF L++LQ+LH+ L I+ +F+GL L LN+ N
Sbjct: 173 FSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPL--LDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQN 331
BLAST of SMED30024248 vs. Ensembl Celegans
Match: lron-15 (ELRR (Extracellular Leucine-Rich Repeat) ONly [Source:UniProtKB/TrEMBL;Acc:Q18902]) HSP 1 Score: 66.6254 bits (161), Expect = 2.932e-11 Identity = 48/133 (36.09%), Postives = 74/133 (55.64%), Query Frame = 2
Query: 620 QSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+++E + L+N QL + F + +L+ L + NQI +I S L L HLSL+ NQ + T N G L L+L+ N+I ++S + F L LQQL L++N++ I +M F L +L YL+L HN
Sbjct: 510 KNLESLFLQNNQLAH--FPSLFRLDKLRHLMLDNNQIQKIDNFSLADLPKLQHLSLAGNQLDIITENMFGSSSSSELKSLNLAHNKIHSISSRSFSDLDNLQQLRLSHNNIRTITSMTFSNLRNLRYLDLSHN 640 HSP 2 Score: 55.0694 bits (131), Expect = 1.280e-7 Identity = 68/227 (29.96%), Postives = 97/227 (42.73%), Query Frame = 2
Query: 344 NLINFTYQRKLTFFNYCKVGILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAF--VNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
N+ ++ + Y V +I S + +KNLESL Q N L+ L L+KL+ L ++N ++ + L+ ++ + L QL+ I F + +LK L + N+I IS SF L L L LS N T F + NL LDLS NRI + L L LHL++N+L ID AF L L L HN
Sbjct: 475 NMSDYLIFEHMPLLTYVDVSFNRIRFISPRVFEKLKNLESL------FLQNNQLAHFP-----SLFRLDKLRHLMLDNNQIQKIDNFSLADLPKLQHLSLAGNQLDIITENMFGSSSSSELKSLNLAHNKIHSISSRSFSDLDNLQQLRLSHNNIR--TITSMTFSNLRNLRYLDLSHNRIIKILPSALYQLPALDVLHLDHNNLNEIDRDAFRSFSDLQSLKLSHN 688
BLAST of SMED30024248 vs. Ensembl Celegans
Match: sym-1 (SYM-1 protein [Source:UniProtKB/TrEMBL;Acc:G5EFP4]) HSP 1 Score: 56.6102 bits (135), Expect = 3.801e-8 Identity = 49/166 (29.52%), Postives = 83/166 (50.00%), Query Frame = 2
Query: 527 ENFLSGL-NKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKY-LTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
++ +GL N +++L + L + L+ + + I+ LK ++ENI +AFVN L + + NQI ++ +F +K L +L L +N F + R + NLI L + +N+I A+ F+ L L L LN N++ I A + +L YL L N
Sbjct: 100 DHAFTGLENVMQELSLSENNLKEVPTSALAGLRVLNILSLKCNKIENITTKAFVNMTSLIDVNLGCNQICSMAADTFANVKMSLQNLILDNNCMTEFPSKA--VRNMNNLIALHIKYNKINAIRQNDFVNLTSLSMLSLNGNNISEIKGGALQNTPNLHYLYLNEN 263
BLAST of SMED30024248 vs. Ensembl Celegans
Match: let-4 (Leucine-rich repeat-containing protein let-4 [Source:UniProtKB/Swiss-Prot;Acc:Q93373]) HSP 1 Score: 53.5286 bits (127), Expect = 2.891e-7 Identity = 47/189 (24.87%), Postives = 88/189 (46.56%), Query Frame = 2
Query: 437 KQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYL 1003
+Q N+ SL YL + G + L+ A + F +L+ L + N ++ + + LS + + + L + ++ NI AF N + +L + N++ ++ GL L +S NQ + T N N F + +L+ LDL+ N++ ++ F+ + L + L+ N L AF + V L
Sbjct: 249 RQAFLNVPSLRYLYLSGNKITKLT--AYQFQTF----EQLEMLDLTNNEIGAIPANSLSGLKQLRQLYLAHNKISNISSNAFTNS-SIVVLVLSSNELKTLTAGIISGLPNLQQVSFRDNQIK--TINRNAFYDAASLVMLDLAKNQLTEIAPTTFLAQLNLLLVDLSENKLPKTPYSAFNSRVGTVLL 428 HSP 2 Score: 50.0618 bits (118), Expect = 3.343e-6 Identity = 36/108 (33.33%), Postives = 57/108 (52.78%), Query Frame = 2
Query: 695 QLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
QL++L + N+I I S GLK L L L+ N+ + ++N F +++ L LS N + L+ + GL LQQ+ +N ++ I+ AF SLV L+L N
Sbjct: 281 QLEMLDLTNNEIGAIPANSLSGLKQLRQLYLAHNKISNISSNA--FTN-SSIVVLVLSSNELKTLTAGIISGLPNLQQVSFRDNQIKTINRNAFYDAASLVMLDLAKN 385
BLAST of SMED30024248 vs. Ensembl Celegans
Match: egg-6 (Leucine-rich repeat-containing protein egg-6 [Source:UniProtKB/Swiss-Prot;Acc:P90920]) HSP 1 Score: 48.9062 bits (115), Expect = 9.369e-6 Identity = 61/222 (27.48%), Postives = 99/222 (44.59%), Query Frame = 2
Query: 422 DSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENF-LSGLNKLKQLKIENIKLDSWSS---------EYL-------SVCQSVEIIILKNLQLENIDFEAFVNCFQLKILT------IIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
D+IP Q+++N +L YL + N++S +I NF L L L++L+++N L +YL S + KNL++ ++ A LK L + N I++I L+F L +S+ +N + N F + L+ L + N +A + MF G+ LQQL + NN L +D +F L L L+L HN
Sbjct: 188 DAIPA-QILRNAANLMYLDLG---SNNIS----EINNFELMNLPFLRELRVQNNTLRRIHPMAFMNVPQLQYLYLQDNIISTLDGNRLQGFKNLEVLDVSNNALYALPSLKDLPNLKQVRVDGNLITKIETLAFSNNPNLQLISVQNNNIVQISRNS--FESLDKLVVLLVGNNSLAKIERGMFDGMKNLQQLSIRNNTLTALDASSFAQLAHLTTLDLGHN 399
BLAST of SMED30024248 vs. Ensembl Fly
Match: rk (gene:FBgn0003255 transcript:FBtr0080610) HSP 1 Score: 68.5514 bits (166), Expect = 1.129e-11 Identity = 55/160 (34.38%), Postives = 82/160 (51.25%), Query Frame = 2
Query: 542 GLNKLKQLKIENIK-LDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
G++KL++L + +++ L S+ L C ++EI+ L ++ + +LK L + N + RI LS + L L LSSNQ E G F + L L LS+NRI AL F G+ KLQ L L N++ +I AF G +L LNL +N
Sbjct: 414 GMSKLRKLILSDVRTLRSFPE--LEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRIPNLS--SCRDLRLLDLSSNQIEKI--QGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEISYIHKEAFSGFTALEDLNLGNN 567
BLAST of SMED30024248 vs. Ensembl Fly
Match: CG7509 (gene:FBgn0035575 transcript:FBtr0073362) HSP 1 Score: 65.4698 bits (158), Expect = 6.674e-11 Identity = 73/256 (28.52%), Postives = 121/256 (47.27%), Query Frame = 2
Query: 383 FNYCKVGILKISSD------------SIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKANLIKIFISADSIQCVE 1114
+N+C G+ + + D S+P Q+I +N + ID +N LS + D GL LK+L I + LD + S+ ++ ++N QLE+ID F L IL + N+I + F + LT +++ NQ ++F N R+ L +LD+S N+I+ LS L KL+ L N + ID+ F GL SL L+ LHN ++ N + ANL+ + ++ + I ++
Sbjct: 146 WNHCTSGVCRCNPDTKSFTCWNTNLKSVPVTQVIP----MNMVNID-LSRNILSTLHKDT---FRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDHRTFWKLRNLNILDLSKNEIGMLPESIFYHAQRLTVINMCDNQIQNFPP--NLLRDQLMLEELDMSRNKISELSSGSIRYLTKLKTLDFGWNQIAKIDDDFFAGLRSLRTLS-LHNNRISSLSGTIFNNL-ANLVTLDLTTNRISHID 389 HSP 2 Score: 52.7582 bits (125), Expect = 6.067e-7 Identity = 37/108 (34.26%), Postives = 55/108 (50.93%), Query Frame = 2
Query: 695 QLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+LK L +NQI++I F GL+ L LSL +N+ + G F + NL+ LDL+ NRI+ + F+ L L +L L N + I F + +L L L N
Sbjct: 326 KLKTLDFGWNQIAKIDDDFFAGLRSLRTLSLHNNRISSLS--GTIFNNLANLVTLDLTTNRISHIDGNAFVELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSN 431
BLAST of SMED30024248 vs. Ensembl Fly
Match: Con (gene:FBgn0005775 transcript:FBtr0309972) HSP 1 Score: 62.003 bits (149), Expect = 9.866e-10 Identity = 56/191 (29.32%), Postives = 95/191 (49.74%), Query Frame = 2
Query: 512 VALDIENFLSGLNKLKQLKIEN---IKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKANLI 1075
+ALD + F + + +L++L +E+ ++D ++ L +C E + L N + + F + +L L + NQI+ ++ F+GL L L L+ N F E+ +L +L+L NRI +S + GL L+ L+L NN L+ IDN G +L+ +N+ N KL PI NL+
Sbjct: 220 MALDQDAFANHI-RLRELNLEHNQIFEMDRYAFRNLPLC---ERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFI--GDTVFAELWSLSELELDDNRIERISERALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQAN-KLETLTFYTFQPIMDNLV 403 HSP 2 Score: 52.7582 bits (125), Expect = 7.265e-7 Identity = 52/182 (28.57%), Postives = 82/182 (45.05%), Query Frame = 2
Query: 545 LNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGL------------------------KYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L L + IE +++ S + +E IIL N + +D +AF N +L+ L + NQI + +F+ L LT L+L+ NQ T+ FR +GNL L L+ N + + +F L L +L L++N +E I A +GL +L LNL +N
Sbjct: 182 LKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEI--FRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERISERALDGLNTLKTLNLRNN 361
BLAST of SMED30024248 vs. Ensembl Fly
Match: Con (gene:FBgn0005775 transcript:FBtr0073375) HSP 1 Score: 62.003 bits (149), Expect = 9.866e-10 Identity = 56/191 (29.32%), Postives = 95/191 (49.74%), Query Frame = 2
Query: 512 VALDIENFLSGLNKLKQLKIEN---IKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKANLI 1075
+ALD + F + + +L++L +E+ ++D ++ L +C E + L N + + F + +L L + NQI+ ++ F+GL L L L+ N F E+ +L +L+L NRI +S + GL L+ L+L NN L+ IDN G +L+ +N+ N KL PI NL+
Sbjct: 220 MALDQDAFANHI-RLRELNLEHNQIFEMDRYAFRNLPLC---ERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFI--GDTVFAELWSLSELELDDNRIERISERALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQAN-KLETLTFYTFQPIMDNLV 403 HSP 2 Score: 52.7582 bits (125), Expect = 7.265e-7 Identity = 52/182 (28.57%), Postives = 82/182 (45.05%), Query Frame = 2
Query: 545 LNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGL------------------------KYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L L + IE +++ S + +E IIL N + +D +AF N +L+ L + NQI + +F+ L LT L+L+ NQ T+ FR +GNL L L+ N + + +F L L +L L++N +E I A +GL +L LNL +N
Sbjct: 182 LKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIMALDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEI--FRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERISERALDGLNTLKTLNLRNN 361
BLAST of SMED30024248 vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330733) HSP 1 Score: 61.6178 bits (148), Expect = 1.376e-9 Identity = 64/230 (27.83%), Postives = 105/230 (45.65%), Query Frame = 2
Query: 626 VEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQC----EHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN-----PKLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPKSVQKVFYSSNDCQSPSEMTRH-----------TTTVSETLPLKAGSPN 1255
VE + L+ L I F +L++L + NQI I SF+ L L L L++N+ E+F T+ +L++LD+S N I + ++F G L+ L L+NN + +D AF+GL+ L L L +N P I L L + +S + C S LS F +S ++ + CQSPS++ + ++E P++ G+ N
Sbjct: 102 VERLELQGNNLTVIYETDFQRLTKLRMLQLTDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSS------ASLLRLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGL-------GRLRALRLSDNPFACDCHLSWLSRFLRSATRLAPYTR-CQSPSQLKGQNVADLHDQEFKCSGLTEHAPMECGAEN 317 HSP 2 Score: 51.9878 bits (123), Expect = 1.514e-6 Identity = 37/101 (36.63%), Postives = 53/101 (52.48%), Query Frame = 2
Query: 722 NQISRISILS-FKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNP 1021
N++ RIS F L +L L L NQ N F ++ +L L N+I +S KMF+GL +L+ L+L +N + + +FE L SL LNL NP
Sbjct: 580 NELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNA--FEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNP 678
BLAST of SMED30024248 vs. Ensembl Zebrafish
Match: lrig3 (leucine-rich repeats and immunoglobulin-like domains 3 [Source:NCBI gene;Acc:564554]) HSP 1 Score: 69.3218 bits (168), Expect = 5.937e-12 Identity = 52/152 (34.21%), Postives = 80/152 (52.63%), Query Frame = 2
Query: 677 AFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLN-PIKA--NLIKIFISADSIQCVEMKS 1123
AF +++L + FN ++ +S GL L L LS N + F + L +LDLS+N+++ L F+GL L+QLH+ NN + FI + AF GL +L L+L N I + + +N P A NL K+F+ + I+ V KS
Sbjct: 131 AFWGLNNMEVLQLEFNNLTEVSKGWLYGLLTLQQLHLSHNSISRIKPDAWEFCQ--KLAELDLSWNQLSRLEEGSFVGLSVLEQLHIGNNRISFIADGAFRGLTNLQTLDLKFNE--ISWTIEDMNGPFSALDNLRKLFLQGNRIRSVTRKS 278 HSP 2 Score: 66.6254 bits (161), Expect = 3.687e-11 Identity = 70/218 (32.11%), Postives = 106/218 (48.62%), Query Frame = 2
Query: 374 LTFFNYCKVGILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQL-----KIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNG-FREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
LTF + LK+ + I + M LN + + + N+L+ V+ + +L GL L+QL I IK D+W CQ + + L QL ++ +FV L+ L I N+IS I+ +F+GL L L L N+ + NG F + NL KL L NRI +++ K F GL L+QL L+NN + + AF + L L+L
Sbjct: 106 LTFQGLHGLRSLKMQRNGI-SRLMDGAFWGLNNMEVLQLEFNNLTEVS---KGWLYGLLTLQQLHLSHNSISRIKPDAWE-----FCQKLAELDLSWNQLSRLEEGSFVGLSVLEQLHIGNNRISFIADGAFRGLTNLQTLDLKFNEISWTIEDMNGPFSALDNLRKLFLQGNRIRSVTRKSFTGLEMLEQLDLSNNAIMSLQANAFSQMKKLSELHL 314
BLAST of SMED30024248 vs. Ensembl Zebrafish
Match: LRRTM4 (leucine rich repeat transmembrane neuronal 4 [Source:HGNC Symbol;Acc:HGNC:19411]) HSP 1 Score: 68.9366 bits (167), Expect = 7.188e-12 Identity = 82/298 (27.52%), Postives = 133/298 (44.63%), Query Frame = 2
Query: 164 LSAIITIELWRFT--LARIPCPQKLCRCDENGQPWKCEIRRDQD-----QIDCSQDLSLSEPINVNLNLINFTYQRKLTFFNYCKVGILKISSDSIPG--KQMIKNLESLNYLIIDGTQ----KNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L +I + W L + PCP+ CRCD G+ CE +D I C Q LSL VNL F +L + L + + I G KQ + + L LI+ + +NS ++ N NKL+ L+ +++ + + + + I N L+ + F +C L+ L + +N++ ++ +F GL LT L L NQ N + F + NL L L +NRI +++ + LQ+L L+ NDL+ +D+ F+ L +L LNL N
Sbjct: 16 LKGVIILSRWLMIPLLVQKPCPRS-CRCD--GKIVYCESNAFRDVPKNVSIGC-QGLSLRYNSLVNLRAGQFASLSQLVW--------LYLDHNYISGVDKQAFQGVRRLKELILSSNKITHLENSTFHSIPNLRNLDLSYNKLQILQ---------PNQFQGLRKLLSLHIRSN-SLKTVPMRVFQDCRNLEFLDLGYNRLRSLTRNAFAGLLKLTELHLEHNQFSKI--NFSHFPRLNNLRALYLQWNRIKSITQGITWTWTSLQKLDLSGNDLQVLDSSIFQCLPNLQTLNLDSN 289
BLAST of SMED30024248 vs. Ensembl Zebrafish
Match: lrig1 (leucine-rich repeats and immunoglobulin-like domains 1 [Source:ZFIN;Acc:ZDB-GENE-031113-23]) HSP 1 Score: 68.1662 bits (165), Expect = 1.807e-11 Identity = 50/158 (31.65%), Postives = 78/158 (49.37%), Query Frame = 2
Query: 545 LNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L KL QL++ +L S+E++ L+ + + AF ++++L + +N + ++ S GL+ L L L++N +F G GF E L +L+LS+N + LS F LV L L L +N + I AF GL SL L L HN
Sbjct: 201 LPKLTQLELSRNRLRLIEGLTFQGLSSLEVLKLQRNNISKLTDGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCE--RLRELNLSYNNLTKLSEGSFAKLVNLISLRLGHNSISHITEGAFRGLSSLRTLELDHN 356
BLAST of SMED30024248 vs. Ensembl Zebrafish
Match: lrig1 (leucine-rich repeats and immunoglobulin-like domains 1 [Source:ZFIN;Acc:ZDB-GENE-031113-23]) HSP 1 Score: 67.781 bits (164), Expect = 2.075e-11 Identity = 50/158 (31.65%), Postives = 78/158 (49.37%), Query Frame = 2
Query: 545 LNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L KL QL++ +L S+E++ L+ + + AF ++++L + +N + ++ S GL+ L L L++N +F G GF E L +L+LS+N + LS F LV L L L +N + I AF GL SL L L HN
Sbjct: 177 LPKLTQLELSRNRLRLIEGLTFQGLSSLEVLKLQRNNISKLTDGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCE--RLRELNLSYNNLTKLSEGSFAKLVNLISLRLGHNSISHITEGAFRGLSSLRTLELDHN 332 HSP 2 Score: 60.8474 bits (146), Expect = 2.950e-9 Identity = 53/191 (27.75%), Postives = 92/191 (48.17%), Query Frame = 2
Query: 455 LESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAAL---SMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+ L+ L + Q+N++S + + GL +++ L ++ L +S L +S+ + L N + N + E + C +L+ L + +N ++++S SF L L L L N H T FR + +L L+L N I+ + F GL L +L L N ++ + AF GL +L +LNL N
Sbjct: 198 FQGLSSLEVLKLQRNNISKLT---DGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCERLRELNLSYNNLTKLSEGSFAKLVNLISLRLGHNSISHITEGA--FRGLSSLRTLELDHNDISGTIEDTSGAFTGLENLNKLTLFGNKIKSVAKKAFSGLEALEHLNLGEN 383
BLAST of SMED30024248 vs. Ensembl Zebrafish
Match: lrig1 (leucine-rich repeats and immunoglobulin-like domains 1 [Source:ZFIN;Acc:ZDB-GENE-031113-23]) HSP 1 Score: 67.781 bits (164), Expect = 2.165e-11 Identity = 50/158 (31.65%), Postives = 78/158 (49.37%), Query Frame = 2
Query: 545 LNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L KL QL++ +L S+E++ L+ + + AF ++++L + +N + ++ S GL+ L L L++N +F G GF E L +L+LS+N + LS F LV L L L +N + I AF GL SL L L HN
Sbjct: 201 LPKLTQLELSRNRLRLIEGLTFQGLSSLEVLKLQRNNISKLTDGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCE--RLRELNLSYNNLTKLSEGSFAKLVNLISLRLGHNSISHITEGAFRGLSSLRTLELDHN 356 HSP 2 Score: 60.8474 bits (146), Expect = 3.022e-9 Identity = 53/191 (27.75%), Postives = 92/191 (48.17%), Query Frame = 2
Query: 455 LESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAAL---SMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+ L+ L + Q+N++S + + GL +++ L ++ L +S L +S+ + L N + N + E + C +L+ L + +N ++++S SF L L L L N H T FR + +L L+L N I+ + F GL L +L L N ++ + AF GL +L +LNL N
Sbjct: 222 FQGLSSLEVLKLQRNNISKLT---DGAFWGLARMRVLHLDYNSLREVNSGSLYGLESLLQLYLANNSISNFNPEGWGFCERLRELNLSYNNLTKLSEGSFAKLVNLISLRLGHNSISHITEGA--FRGLSSLRTLELDHNDISGTIEDTSGAFTGLENLNKLTLFGNKIKSVAKKAFSGLEALEHLNLGEN 407
BLAST of SMED30024248 vs. Ensembl Xenopus
Match: vasn (vasorin [Source:NCBI gene;Acc:448556]) HSP 1 Score: 63.1586 bits (152), Expect = 7.664e-10 Identity = 42/104 (40.38%), Postives = 57/104 (54.81%), Query Frame = 2
Query: 707 LTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L + N IS I SF GL L L LS NQ G FR + NL LDL+ N++ +S F GL +L++L+LN N + I AF+G+ SL+ L L +N
Sbjct: 67 LYVFENGISSIEESSFIGLNGLHLLDLSHNQLSSLP--GGVFRNLANLSNLDLTSNQLTEISADTFQGLSRLERLYLNGNRIRSIHPEAFKGIESLLELKLSNN 168
BLAST of SMED30024248 vs. Ensembl Xenopus
Match: vasn (vasorin [Source:NCBI gene;Acc:448556]) HSP 1 Score: 62.7734 bits (151), Expect = 8.420e-10 Identity = 42/104 (40.38%), Postives = 57/104 (54.81%), Query Frame = 2
Query: 707 LTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L + N IS I SF GL L L LS NQ G FR + NL LDL+ N++ +S F GL +L++L+LN N + I AF+G+ SL+ L L +N
Sbjct: 55 LYVFENGISSIEESSFIGLNGLHLLDLSHNQLSSLP--GGVFRNLANLSNLDLTSNQLTEISADTFQGLSRLERLYLNGNRIRSIHPEAFKGIESLLELKLSNN 156
BLAST of SMED30024248 vs. Ensembl Xenopus
Match: IGFALS (insulin like growth factor binding protein acid labile subunit [Source:NCBI gene;Acc:100489984]) HSP 1 Score: 62.003 bits (149), Expect = 1.460e-9 Identity = 63/219 (28.77%), Postives = 109/219 (49.77%), Query Frame = 2
Query: 305 QDLSLSEPINVNLNLINFTYQRKLTFFNYCKVGILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFI 961
+DL +N+ N I +R TF ++ +L ++ +++ + L LN +I+ N L +A E+ GL KL L +E+ L + + S+ + L+N ++ I+ +F + L L + N+++ ++ SF GLK L++L LSSNQ T + F + L LDLS N++ AL+ +F+ L L+ L L NN L+ I
Sbjct: 304 KDLQFLVELNLGQNKIKILLER--TFEGLAQLELLSLNHNNVQEIRPGSFLGLLNVAVIN-LSGNCLKSLA---EHCFKGLGKLHSLHMESSCLSHIKPQMFAGLSSIRRLFLQNNEIVAIENHSFTDLHGLLELDLRSNKLTHLTTRSFTGLKNLSYLLLSSNQI--LTISPEVFSPVQQLQWLDLSDNQLKALTEDIFLPLSSLRYLSLKNNCLKTI 514 HSP 2 Score: 55.4546 bits (132), Expect = 1.873e-7 Identity = 52/190 (27.37%), Postives = 88/190 (46.32%), Query Frame = 2
Query: 449 KNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+NL L++L + +Q SL AL GL L L +E + S + + Q++ + L N L I+ F L L + +N + + + F L L L L+ N+ + + F +G L +LDLS N + + +F K +L+LN+N + + AF G+ +L +L+L HN
Sbjct: 88 RNLSHLDFLNLQSSQVASLEQQALH------GLKALAHLHLERNMIKSLAPSTFTHTQNLVSLTLNNNFLTKIEDGLFSGLSNLWYLNLGWNLLVVLPDMVFHDLLNLRELVLAGNRLVYLQPSL--FLSLGELKELDLSGNSLKGIKANVFTRQQKTHKLYLNHNHISTVAPRAFSGMKNLRWLDLSHN 269 HSP 3 Score: 50.0618 bits (118), Expect = 7.755e-6 Identity = 44/159 (27.67%), Postives = 81/159 (50.94%), Query Frame = 2
Query: 533 FLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
FLS L +LK+L + L + + Q + L + + + AF L+ L + N+++ + +F GL L L LS+N + F+++ L++L+L N+I L + F GL +L+ L LN+N+++ I +F GL+++ +NL
Sbjct: 207 FLS-LGELKELDLSGNSLKGIKANVFTRQQKTHKLYLNHNHISTVAPRAFSGMKNLRWLDLSHNRLTALYEDTFFGLPSLNVLRLSNNSLT--SLRPRIFKDLQFLVELNLGQNKIKILLERTFEGLAQLELLSLNHNNVQEIRPGSFLGLLNVAVINL 362
BLAST of SMED30024248 vs. Ensembl Xenopus
Match: rorc (RAR related orphan receptor C [Source:Xenbase;Acc:XB-GENE-481075]) HSP 1 Score: 62.003 bits (149), Expect = 2.075e-9 Identity = 41/128 (32.03%), Postives = 68/128 (53.12%), Query Frame = 2
Query: 596 SSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNG-FREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAF 976
SS S CQ ++ ++L + L +D + + L +L + +N IS I+ +FKGLK L L L N+ + NG F + +L KL L N+I +++ + F G+ L+ L+L N L + + AF
Sbjct: 286 SSAGWSFCQKLQELVLSHNNLTRLDEGSLADLGVLDVLRLSYNSISHIAEGAFKGLKSLRILELDHNEISGTIEDTNGAFIGLESLNKLTLFGNKIKSVAKRAFSGIESLEHLNLGENALRSVHSEAF 413
BLAST of SMED30024248 vs. Ensembl Xenopus
Match: rorc (RAR related orphan receptor C [Source:Xenbase;Acc:XB-GENE-481075]) HSP 1 Score: 62.003 bits (149), Expect = 2.118e-9 Identity = 41/128 (32.03%), Postives = 68/128 (53.12%), Query Frame = 2
Query: 596 SSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNG-FREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAF 976
SS S CQ ++ ++L + L +D + + L +L + +N IS I+ +FKGLK L L L N+ + NG F + +L KL L N+I +++ + F G+ L+ L+L N L + + AF
Sbjct: 286 SSAGWSFCQKLQELVLSHNNLTRLDEGSLADLGVLDVLRLSYNSISHIAEGAFKGLKSLRILELDHNEISGTIEDTNGAFIGLESLNKLTLFGNKIKSVAKRAFSGIESLEHLNLGENALRSVHSEAF 413
BLAST of SMED30024248 vs. Ensembl Mouse
Match: Lgr6 (leucine-rich repeat-containing G protein-coupled receptor 6 [Source:MGI Symbol;Acc:MGI:2441805]) HSP 1 Score: 67.3958 bits (163), Expect = 2.725e-11 Identity = 75/294 (25.51%), Postives = 124/294 (42.18%), Query Frame = 2
Query: 206 ARIPCPQKLCRCDENGQPWKCEIRRDQDQIDCSQDLSLSEPINVNLNLI--NFTYQRKLTFFNYCKVGILKISSDS---IPGKQMIKNLESLNYLIIDGTQKNSLSGVALDI---------------------ENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
R CP C C E+G + D ++ S + +P+ L+L N T + F + + L++S + IPG Q L SL L++ Q N L G+ + E GL+ L+ L +++ L L+ +++ + L + +I AF N L +L + N+I + SF+GL L L L+ N+ + F R +G L +L N I A+ K F+G LQ +H +N ++F+ AF+ L L L+L
Sbjct: 31 GRPACPAP-CHCQEDG----IMLSADCSELGLSVVPADLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPG-QAFSGLHSLKILML---QSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNHIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLHNLETLDLNYNELQEFPL---AIRTLGRLQELGFHNNNIKAIPEKAFMGSPLLQTIHFYDNPIQFVGRSAFQYLSKLHTLSL 312 HSP 2 Score: 60.4622 bits (145), Expect = 4.568e-9 Identity = 50/161 (31.06%), Postives = 76/161 (47.20%), Query Frame = 2
Query: 545 LNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLD---LSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L L++L++ L + S S++I++L++ QL I EA L+ L + N IS + SF+GL L HL L N R + NL L L+ N I + F L L LHL+NN ++ + +FEGL +L L+L +N
Sbjct: 89 LRFLEELRLSGNHLSHIPGQAFSGLHSLKILMLQSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPV-----RALNNLPALQAMTLALNHIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLHNLETLDLNYN 244
BLAST of SMED30024248 vs. Ensembl Mouse
Match: Lrrtm3 (leucine rich repeat transmembrane neuronal 3 [Source:MGI Symbol;Acc:MGI:2389177]) HSP 1 Score: 65.855 bits (159), Expect = 6.100e-11 Identity = 45/121 (37.19%), Postives = 65/121 (53.72%), Query Frame = 2
Query: 656 LENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L+ + + F QL L + N IS I +F G++ L L LSSN+ +F N FR + NL LDLS+N++ +L + F GL KL LHL +N L I F+ +L L+L +N
Sbjct: 73 LQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNT--FRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYN 191 HSP 2 Score: 60.8474 bits (146), Expect = 2.390e-9 Identity = 51/201 (25.37%), Postives = 93/201 (46.27%), Query Frame = 2
Query: 530 NFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLN-------PIKANLIKIFISADSIQCV 1111
N GLN+L L +++ + + + + ++ +IL + ++ F L+ L + +NQ+ + F+GL+ L L L SN T F++ NL LDL +NRI +L+ +F G+++L++LHL +N ++ F L+SL L + N ++ + + N I+ F QCV
Sbjct: 79 NQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLR--TIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYMQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCV 277
BLAST of SMED30024248 vs. Ensembl Mouse
Match: Lrig2 (leucine-rich repeats and immunoglobulin-like domains 2 [Source:MGI Symbol;Acc:MGI:2443718]) HSP 1 Score: 66.2402 bits (160), Expect = 6.379e-11 Identity = 63/198 (31.82%), Postives = 94/198 (47.47%), Query Frame = 2
Query: 401 GILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQL-----KIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGN-GFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAF 976
GI K+ + G + N+E L + N+L+GV + +L GL L+QL IE I D+W CQ + + L QL +D AFV L+ L + N+++ I+ F+ L L L L +N + + F + +L KL L NRI +++ K FIGL L+ L LNNN + I AF
Sbjct: 249 GISKLKDGAFFG---LNNMEELEL------EHNNLTGVN---KGWLYGLRMLQQLYMSQNAIEKISPDAWE-----FCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDISWAIEDASEAFSGLKSLTKLILQGNRIKSVTQKAFIGLESLEYLDLNNNAIMSIQENAF 429
BLAST of SMED30024248 vs. Ensembl Mouse
Match: Lrrtm2 (leucine rich repeat transmembrane neuronal 2 [Source:MGI Symbol;Acc:MGI:2389174]) HSP 1 Score: 65.855 bits (159), Expect = 6.601e-11 Identity = 46/123 (37.40%), Postives = 69/123 (56.10%), Query Frame = 2
Query: 641 LKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
L++ + ++ + F + QL L + NQIS + +F+GL L L LSSN+ F F ++ NL LDLSFN++++L ++F GL KLQ LHL +N L I F SL +L+L
Sbjct: 68 LRHNHITALERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI--FYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDL 188 HSP 2 Score: 56.225 bits (134), Expect = 6.671e-8 Identity = 58/187 (31.02%), Postives = 94/187 (50.27%), Query Frame = 2
Query: 566 KIENIKLDSWSSEYLSVCQSVEIIILKN--LQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLC-LNPIKANLIKIFISADSIQCVEM 1117
+I +K D++ Y + E+I+ N L N F +N L+ L + FNQ+S + F GL+ L L L SN T F + +L LDLS NR+ +L+ F GL+KL++LHL +N L I+ F L SL L L N + +L C ++ + L K+ ++ + I+ +++
Sbjct: 96 QISTVKEDAFQGLY----KLKELILSSNKIFYLPNTTFTQLIN---LQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLR--TIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNK---ISNLTCGMDWTWSTLEKLDLTGNEIKAIDL 270 HSP 3 Score: 51.9878 bits (123), Expect = 1.556e-6 Identity = 44/159 (27.67%), Postives = 75/159 (47.17%), Query Frame = 2
Query: 542 GLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
GL KL+ L + + L + C+S+E + L +L ++ F +L+ L + NQ+++I+ F L L L L N+ + T + L KLDL+ N I A+ + +F + L+ L ++NN L +D+ L SL + L N
Sbjct: 155 GLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMDW--TWSTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLKSLTTVGLSGN 311
BLAST of SMED30024248 vs. Ensembl Mouse
Match: Lrig2 (leucine-rich repeats and immunoglobulin-like domains 2 [Source:MGI Symbol;Acc:MGI:2443718]) HSP 1 Score: 66.2402 bits (160), Expect = 6.647e-11 Identity = 63/198 (31.82%), Postives = 94/198 (47.47%), Query Frame = 2
Query: 401 GILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQL-----KIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGN-GFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAF 976
GI K+ + G + N+E L + N+L+GV + +L GL L+QL IE I D+W CQ + + L QL +D AFV L+ L + N+++ I+ F+ L L L L +N + + F + +L KL L NRI +++ K FIGL L+ L LNNN + I AF
Sbjct: 249 GISKLKDGAFFG---LNNMEELEL------EHNNLTGVN---KGWLYGLRMLQQLYMSQNAIEKISPDAWE-----FCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDISWAIEDASEAFSGLKSLTKLILQGNRIKSVTQKAFIGLESLEYLDLNNNAIMSIQENAF 429
BLAST of SMED30024248 vs. UniProt/SwissProt
Match: sp|Q3UVD5|LGR6_MOUSE (Leucine-rich repeat-containing G-protein coupled receptor 6 OS=Mus musculus OX=10090 GN=Lgr6 PE=2 SV=1) HSP 1 Score: 67.3958 bits (163), Expect = 1.906e-10 Identity = 75/294 (25.51%), Postives = 124/294 (42.18%), Query Frame = 2
Query: 206 ARIPCPQKLCRCDENGQPWKCEIRRDQDQIDCSQDLSLSEPINVNLNLI--NFTYQRKLTFFNYCKVGILKISSDS---IPGKQMIKNLESLNYLIIDGTQKNSLSGVALDI---------------------ENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
R CP C C E+G + D ++ S + +P+ L+L N T + F + + L++S + IPG Q L SL L++ Q N L G+ + E GL+ L+ L +++ L L+ +++ + L + +I AF N L +L + N+I + SF+GL L L L+ N+ + F R +G L +L N I A+ K F+G LQ +H +N ++F+ AF+ L L L+L
Sbjct: 31 GRPACPAP-CHCQEDG----IMLSADCSELGLSVVPADLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPG-QAFSGLHSLKILML---QSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNHIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLHNLETLDLNYNELQEFPL---AIRTLGRLQELGFHNNNIKAIPEKAFMGSPLLQTIHFYDNPIQFVGRSAFQYLSKLHTLSL 312 HSP 2 Score: 60.4622 bits (145), Expect = 3.195e-8 Identity = 50/161 (31.06%), Postives = 76/161 (47.20%), Query Frame = 2
Query: 545 LNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLD---LSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L L++L++ L + S S++I++L++ QL I EA L+ L + N IS + SF+GL L HL L N R + NL L L+ N I + F L L LHL+NN ++ + +FEGL +L L+L +N
Sbjct: 89 LRFLEELRLSGNHLSHIPGQAFSGLHSLKILMLQSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPV-----RALNNLPALQAMTLALNHIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLHNLETLDLNYN 244
BLAST of SMED30024248 vs. UniProt/SwissProt
Match: sp|O43300|LRRT2_HUMAN (Leucine-rich repeat transmembrane neuronal protein 2 OS=Homo sapiens OX=9606 GN=LRRTM2 PE=1 SV=3) HSP 1 Score: 65.855 bits (159), Expect = 4.056e-10 Identity = 46/123 (37.40%), Postives = 69/123 (56.10%), Query Frame = 2
Query: 641 LKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
L++ + ++ + F + QL L + NQIS + +F+GL L L LSSN+ F F ++ NL LDLSFN++++L ++F GL KLQ LHL +N L I F SL +L+L
Sbjct: 68 LRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI--FYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDL 188 HSP 2 Score: 55.4546 bits (132), Expect = 7.478e-7 Identity = 58/187 (31.02%), Postives = 92/187 (49.20%), Query Frame = 2
Query: 566 KIENIKLDSWSSEYLSVCQSVEIIILKN--LQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLC-LNPIKANLIKIFISADSIQCVEM 1117
+I +K D++ Y + E+I+ N L N F +N L+ L + FNQ+S + F GL+ L L L SN T F + +L LDLS NR+ +L+ F GL+KL++LHL +N L I+ F L SL L L N + +L C + L K+ ++ + I+ +++
Sbjct: 96 QISTVKEDAFQGLY----KLKELILSSNKIFYLPNTTFTQLIN---LQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLR--TIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNK---ISNLTCGMEWTWGTLEKLDLTGNEIKAIDL 270 HSP 3 Score: 53.9138 bits (128), Expect = 2.507e-6 Identity = 45/159 (28.30%), Postives = 75/159 (47.17%), Query Frame = 2
Query: 542 GLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
GL KL+ L + + L + C+S+E + L +L ++ F +L+ L + NQ+++I+ F L L L L N+ + T G L KLDL+ N I A+ + +F + L+ L ++NN L +D+ L SL + L N
Sbjct: 155 GLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEW--TWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGN 311
BLAST of SMED30024248 vs. UniProt/SwissProt
Match: sp|D3ZAL8|LRRT3_RAT (Leucine-rich repeat transmembrane neuronal protein 3 OS=Rattus norvegicus OX=10116 GN=Lrrtm3 PE=3 SV=1) HSP 1 Score: 66.2402 bits (160), Expect = 4.085e-10 Identity = 45/121 (37.19%), Postives = 65/121 (53.72%), Query Frame = 2
Query: 656 LENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L+ + + F QL L + N IS I +F G++ L L LSSN+ +F N FR + NL LDLS+N++ +L + F GL KL LHL +N L I F+ +L L+L +N
Sbjct: 73 LQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNT--FRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYN 191 HSP 2 Score: 61.2326 bits (147), Expect = 1.532e-8 Identity = 51/201 (25.37%), Postives = 93/201 (46.27%), Query Frame = 2
Query: 530 NFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLN-------PIKANLIKIFISADSIQCV 1111
N GLN+L L +++ + + + + ++ +IL + ++ F L+ L + +NQ+ + F+GL+ L L L SN T F++ NL LDL +NRI +L+ +F G+++L++LHL +N ++ F L+SL L + N ++ + + N I+ F QCV
Sbjct: 79 NQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLR--TIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYMQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCV 277
BLAST of SMED30024248 vs. UniProt/SwissProt
Match: sp|Q8BZ81|LRRT3_MOUSE (Leucine-rich repeat transmembrane neuronal protein 3 OS=Mus musculus OX=10090 GN=Lrrtm3 PE=2 SV=2) HSP 1 Score: 65.855 bits (159), Expect = 4.267e-10 Identity = 45/121 (37.19%), Postives = 65/121 (53.72%), Query Frame = 2
Query: 656 LENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L+ + + F QL L + N IS I +F G++ L L LSSN+ +F N FR + NL LDLS+N++ +L + F GL KL LHL +N L I F+ +L L+L +N
Sbjct: 73 LQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNT--FRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYN 191 HSP 2 Score: 60.8474 bits (146), Expect = 1.672e-8 Identity = 51/201 (25.37%), Postives = 93/201 (46.27%), Query Frame = 2
Query: 530 NFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLN-------PIKANLIKIFISADSIQCV 1111
N GLN+L L +++ + + + + ++ +IL + ++ F L+ L + +NQ+ + F+GL+ L L L SN T F++ NL LDL +NRI +L+ +F G+++L++LHL +N ++ F L+SL L + N ++ + + N I+ F QCV
Sbjct: 79 NQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLR--TIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYMQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCV 277
BLAST of SMED30024248 vs. UniProt/SwissProt
Match: sp|Q52KR2|LRIG2_MOUSE (Leucine-rich repeats and immunoglobulin-like domains protein 2 OS=Mus musculus OX=10090 GN=Lrig2 PE=1 SV=1) HSP 1 Score: 66.2402 bits (160), Expect = 4.462e-10 Identity = 63/198 (31.82%), Postives = 94/198 (47.47%), Query Frame = 2
Query: 401 GILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQL-----KIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGN-GFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAF 976
GI K+ + G + N+E L + N+L+GV + +L GL L+QL IE I D+W CQ + + L QL +D AFV L+ L + N+++ I+ F+ L L L L +N + + F + +L KL L NRI +++ K FIGL L+ L LNNN + I AF
Sbjct: 249 GISKLKDGAFFG---LNNMEELEL------EHNNLTGVN---KGWLYGLRMLQQLYMSQNAIEKISPDAWE-----FCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDISWAIEDASEAFSGLKSLTKLILQGNRIKSVTQKAFIGLESLEYLDLNNNAIMSIQENAF 429
BLAST of SMED30024248 vs. TrEMBL
Match: A0A0D2WM22 (Uncharacterized protein OS=Capsaspora owczarzaki (strain ATCC 30864) OX=595528 GN=CAOG_002281 PE=4 SV=1) HSP 1 Score: 85.1149 bits (209), Expect = 1.540e-13 Identity = 69/233 (29.61%), Postives = 109/233 (46.78%), Query Frame = 2
Query: 329 INVNLNLINFTYQRKLTFFNYCKVGILKISSD---SIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+++NL T F + K+ L ++++ S+P + L +L L +D Q S+S +A + L L L + N ++ S + ++ + L + Q+ +I AF + L L++ NQI+ IS +F GL L LSL+ NQ + N F + L LDL+ N+I +S F GL L L L+NN + I AF GL L YL L +N
Sbjct: 158 VSLNLEFTQITTISAAAFTSLAKLKNLYLNNNQITSVP-ESAFTGLTALVSLELDNNQITSISALAF------ANLTALSYLGLANNRITGISENTFTGLTALAALYLLDNQITSISANAFTDLTALTTLSLALNQITSISANAFTGLTTLAGLSLALNQITGIS--ANAFTGLTTLAGLDLALNQITGISTNAFTGLTTLAVLRLDNNQIASISANAFTGLTMLFYLTLHNN 381 HSP 2 Score: 67.781 bits (164), Expect = 3.704e-8 Identity = 44/126 (34.92%), Postives = 65/126 (51.59%), Query Frame = 2
Query: 641 LKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L++ Q+ I +AF L L + N I+ IS +F L L++L LS Q + N F + L+ L+L F +I +S F L KL+ L+LNNN + + AF GL +LV L L +N
Sbjct: 90 LQSNQITAISPDAFAGLTSLNSLYLSDNPITSISANAFSDLTELSYLHLSYTQLTDIS--ANAFTTLPALVSLNLEFTQITTISAAAFTSLAKLKNLYLNNNQITSVPESAFTGLTALVSLELDNN 213 HSP 3 Score: 67.3958 bits (163), Expect = 5.108e-8 Identity = 59/191 (30.89%), Postives = 95/191 (49.74%), Query Frame = 2
Query: 449 KNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNP 1021
NL +L+YL G N ++G++ EN +GL L L + + ++ S S+ + ++ + L Q+ +I AF L L++ NQI+ IS +F GL L L L+ NQ +TN F + L L L N+IA++S F GL L L L+NN + F+GL + + L++ +P
Sbjct: 224 ANLTALSYL---GLANNRITGIS---ENTFTGLTALAALYLLDNQITSISANAFTDLTALTTLSLALNQITSISANAFTGLTTLAGLSLALNQITGISANAFTGLTTLAGLDLALNQITGISTNA--FTGLTTLAVLRLDNNQIASISANAFTGLTMLFYLTLHNNSFTTLPPGLFKGLRNGLCLSMETSP 406
BLAST of SMED30024248 vs. TrEMBL
Match: A0A0D2X5D9 (TKL protein kinase OS=Capsaspora owczarzaki (strain ATCC 30864) OX=595528 GN=CAOG_009123 PE=4 SV=1) HSP 1 Score: 84.3445 bits (207), Expect = 3.310e-13 Identity = 61/188 (32.45%), Postives = 91/188 (48.40%), Query Frame = 2
Query: 455 LESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L L+ L + Q SL N SGL + QL + N L + S + +++ ++L N Q+ ++ AF L +L + NQI+ I +F GL L L L+SN+ T N F + L LD+S N+I +L F GL + QLHL NN + + AF GL +L L+L +N
Sbjct: 586 LTHLSLLELSNNQITSLPA------NAFSGLTAMTQLSLYNNSLSAVPSSAFTGLTALQALLLYNNQITSVAANAFTGLTALVLLHLYRNQITTIPASAFAGLSALVQLYLNSNRIT--TIFANAFPSLTKLTYLDISNNQITSLPANAFTGLTAMTQLHLYNNLFSTVPSSAFTGLTALQILSLFNN 765 HSP 2 Score: 82.0333 bits (201), Expect = 1.956e-12 Identity = 60/188 (31.91%), Postives = 91/188 (48.40%), Query Frame = 2
Query: 455 LESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L +L L + Q S+S N SGL+KL L++ N L + S + ++ ++L N Q+ + AF L+ L + NQI+ ++I +F GL L L L +NQ T N F + L L L N ++A+ F GL L QL L+ N + + AF GL +L+YL L +N
Sbjct: 202 LTALVQLYLYNNQITSISA------NAFSGLSKLNTLQLNNNWLSAIPSSAFTGLTALTQLLLYNNQITTVPSSAFTGLTALQFLYLYNNQIATVAINAFSGLTALVQLRLDTNQIT--TVPANAFSGLSKLNTLHLYNNWLSAIPSSAFTGLTALTQLRLDTNQITTVPANAFSGLTALIYLYLYNN 381 HSP 3 Score: 78.1814 bits (191), Expect = 3.127e-11 Identity = 61/205 (29.76%), Postives = 99/205 (48.29%), Query Frame = 2
Query: 404 ILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
I I+S + G ++ L+ N N ++ V N SGL+KL L + N L + S + ++ ++L N Q+ + AF L++L + NQI+ ++I +F GL L L L +NQ + + N F + L L L+ N ++A+ F GL L QL L NN + + + AF GL +L +L L +N
Sbjct: 95 ITNIASSAFSGLSVLNTLDLTN---------NQITTVP---ANAFSGLSKLNTLYLYNNWLSAIPSSAFTGLTALTQLLLHNNQITTVPSSAFTGLTALQLLYLYNNQIATVAIDAFSGLTALVQLYLYNNQIT--SISANAFSGLSKLNTLQLNNNWLSAIPSSAFTGLTALTQLLLYNNQITTVPSSAFTGLTALQFLYLYNN 285 HSP 4 Score: 75.0998 bits (183), Expect = 2.591e-10 Identity = 60/188 (31.91%), Postives = 91/188 (48.40%), Query Frame = 2
Query: 452 NLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSF--NRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
+L L YL I Q SL N +GL + QL + N + S + +++I+ L N Q+ ++ AF + L L + NQI+ I +F GL L+ L L++N T + F + L +L LS N+I +S F GL LQ L+LN+N + I AF GL +L +L+L
Sbjct: 705 SLTKLTYLDISNNQITSLPA------NAFTGLTAMTQLHLYNNLFSTVPSSAFTGLTALQILSLFNNQISSVAANAFTSLTALVQLQLYGNQITTIPASAFSGLSKLSLLQLNNNWLSAIPT--SAFTGLTALTQLQLSLYGNQITTISASAFAGLTALQALYLNDNTITTIAANAFAGLTALNWLDL 884 HSP 5 Score: 75.0998 bits (183), Expect = 3.054e-10 Identity = 61/174 (35.06%), Postives = 82/174 (47.13%), Query Frame = 2
Query: 497 NSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
N ++ VA+D SGL L QL + N ++ S S+ S + + L N L I AF L L + NQI+ + +F GL L L L +NQ T N F + L++L L N+I + F GL KL LHL NN L I + AF GL +L L L N
Sbjct: 189 NQIATVAIDA---FSGLTALVQLYLYNNQITSISANAFSGLSKLNTLQLNNNWLSAIPSSAFTGLTALTQLLLYNNQITTVPSSAFTGLTALQFLYLYNNQIA--TVAINAFSGLTALVQLRLDTNQITTVPANAFSGLSKLNTLHLYNNWLSAIPSSAFTGLTALTQLRLDTN 357 HSP 6 Score: 68.9366 bits (167), Expect = 2.637e-8 Identity = 61/188 (32.45%), Postives = 86/188 (45.74%), Query Frame = 2
Query: 455 LESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L L YL + Q S+ A SGL L QL + N L + S + ++ + L N Q+ + AF L L + NQI+ IS +F G+ L L L SN+ N F + +L L+LS N+I +L F GL + QL L NN L + + AF GL +L L L +N
Sbjct: 466 LTKLTYLDLSLNQLTSIPAGAF------SGLTALTQLLLYNNWLSAVPSSAFTGLTALLYLYLYNNQITTVAANAFTGLTALVQLQLYGNQITTISASAFAGMSSLVQLYLYSNRITAIFVNA--FTGLTHLSLLELSNNQITSLPANAFSGLTAMTQLSLYNNSLSAVPSSAFTGLTALQALLLYNN 645 HSP 7 Score: 67.0106 bits (162), Expect = 9.859e-8 Identity = 51/165 (30.91%), Postives = 81/165 (49.09%), Query Frame = 2
Query: 524 IENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+ N +GL KL L + +L S + S ++ ++L N L + AF L L + NQI+ ++ +F GL L L L NQ T + + F + +L++L L NRI A+ + F GL L L L+NN + + AF GL ++ L+L +N
Sbjct: 459 LANAFTGLTKLTYLDLSLNQLTSIPAGAFSGLTALTQLLLYNNWLSAVPSSAFTGLTALLYLYLYNNQITTVAANAFTGLTALVQLQLYGNQIT--TISASAFAGMSSLVQLYLYSNRITAIFVNAFTGLTHLSLLELSNNQITSLPANAFSGLTAMTQLSLYNN 621 HSP 8 Score: 62.3882 bits (150), Expect = 2.927e-6 Identity = 47/158 (29.75%), Postives = 73/158 (46.20%), Query Frame = 2
Query: 536 LSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
+GL+ L QL + + ++ + + + + + N Q+ ++ AF + L + N S + +F GL L LSL +NQ + N F + L++L L N+I + F GL KL L LNNN L I AF GL +L L L
Sbjct: 679 FAGLSALVQLYLNSNRITTIFANAFPSLTKLTYLDISNNQITSLPANAFTGLTAMTQLHLYNNLFSTVPSSAFTGLTALQILSLFNNQIS--SVAANAFTSLTALVQLQLYGNQITTIPASAFSGLSKLSLLQLNNNWLSAIPTSAFTGLTALTQLQL 834 HSP 9 Score: 61.2326 bits (147), Expect = 6.622e-6 Identity = 50/161 (31.06%), Postives = 75/161 (46.58%), Query Frame = 2
Query: 536 LSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+GL L+ L + N ++ + + S ++ + L Q+ + AF +L L + N +S I +F GL LT L L +NQ T N F + LI L L N+I + F GL L QL+L NN + I + A GL +L L L +N
Sbjct: 271 FTGLTALQFLYLYNNQIATVAINAFSGLTALVQLRLDTNQITTVPANAFSGLSKLNTLHLYNNWLSAIPSSAFTGLTALTQLRLDTNQIT--TVPANAFSGLTALIYLYLYNNQITTVPANAFSGLTALVQLYLYNNQITTIPSSALTGLSALTQLYLYNN 429 HSP 10 Score: 60.8474 bits (146), Expect = 8.569e-6 Identity = 45/132 (34.09%), Postives = 68/132 (51.52%), Query Frame = 2
Query: 623 SVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+ I+ L+N Q+ +I AF + L L++ N I+ I+ +F GL L L L++NQ T N F + L L L N ++A+ F GL L QL L+NN + + + AF GL +L L L +N
Sbjct: 60 TTTILYLQNNQITSISANAFSSLTLLTYLSLSSNPITNIASSAFSGLSVLNTLDLTNNQIT--TVPANAFSGLSKLNTLYLYNNWLSAIPSSAFTGLTALTQLLLHNNQITTVPSSAFTGLTALQLLYLYNN 189 HSP 11 Score: 60.4622 bits (145), Expect = 9.831e-6 Identity = 54/183 (29.51%), Postives = 81/183 (44.26%), Query Frame = 2
Query: 536 LSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNG----------------------NGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+GL L QL+++ ++ + + S ++ + L N Q+ + AF L L + NQI+ I + GL LT L L +NQ NG N F + L LDLS N++ ++ F GL L QL L NN L + + AF GL +L+YL L +N
Sbjct: 343 FTGLTALTQLRLDTNQITTVPANAFSGLTALIYLYLYNNQITTVPANAFSGLTALVQLYLYNNQITTIPSSALTGLSALTQLYLYNNQITSVPANGFSGLTALTDLRLFNNTITSILANAFTGLTKLTYLDLSLNQLTSIPAGAFSGLTALTQLLLYNNWLSAVPSSAFTGLTALLYLYLYNN 525
BLAST of SMED30024248 vs. TrEMBL
Match: A0A0D2U6J4 (LRRNT domain-containing protein OS=Capsaspora owczarzaki (strain ATCC 30864) OX=595528 GN=CAOG_002031 PE=4 SV=1) HSP 1 Score: 83.5741 bits (205), Expect = 4.461e-13 Identity = 68/224 (30.36%), Postives = 104/224 (46.43%), Query Frame = 2
Query: 356 FTYQRKLT--FFNYCKVGILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNP 1021
FT LT FF Y + I I +D+ G L SL YL + Q S+SG A +GL L L + ++ S ++ + ++ + L+N Q+ +I AF L L NQI+ I +F G+ LT+LSL N+ + N F + L L L N+I ++ + F GL L L+L+ N + I + +F L +L L L +NP
Sbjct: 126 FTGLTALTALFFAYNQ--ITSIPADTFTG------LTSLTYLSLQNNQVTSISGTAF------TGLTALTSLSLGPNQITSIPADTFTGLTALTTLSLQNNQITSISGTAFTGLTALTCLYFGSNQITSIPAGAFTGMTSLTYLSLYLNKITSI--SANAFAGLTALTYLSLFNNKITSIPVGAFTGLTGLTDLYLDGNQITSIPSSSFTNLTALTALALQNNP 333 HSP 2 Score: 70.8626 bits (172), Expect = 3.700e-9 Identity = 46/149 (30.87%), Postives = 68/149 (45.64%), Query Frame = 2
Query: 557 KQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYL 1003
QL ++ + S S+ + ++ + L+ Q+ I F L L +NQI+ I +F GL LT+LSL +NQ +G F + L L L N+I ++ F GL L L L NN + I AF GL +L L
Sbjct: 85 TQLTLDLNSITSISANAFTGLTALTYLSLQYNQITGIPAGTFTGLTALTALFFAYNQITSIPADTFTGLTSLTYLSLQNNQVTSI--SGTAFTGLTALTSLSLGPNQITSIPADTFTGLTALTTLSLQNNQITSISGTAFTGLTALTCL 231
BLAST of SMED30024248 vs. TrEMBL
Match: A0A0D2VQM3 (TKL protein kinase OS=Capsaspora owczarzaki (strain ATCC 30864) OX=595528 GN=CAOG_003855 PE=4 SV=1) HSP 1 Score: 83.1889 bits (204), Expect = 7.255e-13 Identity = 57/163 (34.97%), Postives = 84/163 (51.53%), Query Frame = 2
Query: 536 LSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPK 1024
+GLN L +L + N ++ S S+ + S++++ L N Q+ +I AF L L++ NQI+ IS +F GL LT LSL SN + + F + L L+L N+I +S F GL L+ L+LNNN + AF GL +L L L NP
Sbjct: 80 FTGLNALIRLDLSNNQITSISANAFTGAISLQVLYLYNNQIPSISASAFTGLTNLTQLSLQNNQITSISSSAFTGLTALTDLSLGSNWLSAIPS--SAFTGLTALTHLNLYNNQITTISANAFSGLAALRFLYLNNNQITTFSASAFAGLTALSRLALNANPA 240 HSP 2 Score: 69.3218 bits (168), Expect = 1.873e-8 Identity = 52/160 (32.50%), Postives = 81/160 (50.62%), Query Frame = 2
Query: 530 NFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
N +G L+ L + N ++ S S+ + ++ + L+N Q+ +I AF L L++ N +S I +F GL LTHL+L +NQ T + N F + L L L+ N+I S F GL L +L LN N + F+GL +L+YL+L
Sbjct: 102 NAFTGAISLQVLYLYNNQIPSISASAFTGLTNLTQLSLQNNQITSISSSAFTGLTALTDLSLGSNWLSAIPSSAFTGLTALTHLNLYNNQIT--TISANAFSGLAALRFLYLNNNQITTFSASAFAGLTALSRLALNANPATTLPPGLFKGLPNLMYLSL 259 HSP 3 Score: 61.2326 bits (147), Expect = 5.421e-6 Identity = 51/153 (33.33%), Postives = 72/153 (47.06%), Query Frame = 2
Query: 599 SEYLSVCQSVEI-------------IILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
SE L CQS + + L + Q+ +I AF L L + NQI+ IS +F G L L L +NQ + + F + NL +L L N+I ++S F GL L L L +N L I + AF GL +L +LNL +N
Sbjct: 40 SETLVSCQSKALTSIPTDIPVTTVSLFLYDNQITSIFSSAFTGLNALIRLDLSNNQITSISANAFTGAISLQVLYLYNNQIPSIS--ASAFTGLTNLTQLSLQNNQITSISSSAFTGLTALTDLSLGSNWLSAIPSSAFTGLTALTHLNLYNN 190
BLAST of SMED30024248 vs. TrEMBL
Match: A0A0D2VM23 (Uncharacterized protein OS=Capsaspora owczarzaki (strain ATCC 30864) OX=595528 GN=CAOG_002334 PE=4 SV=1) HSP 1 Score: 81.6481 bits (200), Expect = 8.736e-13 Identity = 55/158 (34.81%), Postives = 83/158 (52.53%), Query Frame = 2
Query: 545 LNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L KL QL ++N + S S+ + ++ + L Q+ +I AF + L+ L + N+I+ IS +F GL L +L LS NQ + N F ++ +L L L FN++++L+ F GL L QL L NN + I AF GL +L L LHN
Sbjct: 9 LTKLTQLSLDNTPITSISANAFAGLSALTQMFLYQTQITSISASAFADLRSLQKLYLYGNRITSISANAFTGLTKLAYLDLSYNQITSIS--ANAFADLSSLTDLRLYFNQMSSLAANTFTGLSALTQLSLLNNQITAISANAFTGLNALKLL-YLHN 163
BLAST of SMED30024248 vs. Ensembl Cavefish
Match: lrig2 (leucine rich repeats and immunoglobulin like domains 2 [Source:NCBI gene;Acc:103036991]) HSP 1 Score: 71.633 bits (174), Expect = 1.064e-12 Identity = 58/196 (29.59%), Postives = 99/196 (50.51%), Query Frame = 2
Query: 443 MIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNG-FREIGNLIKLDLSFNRIAAL---SMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
+ K LE+L L + Q+N G+ ++ L GL+ +++L++E+ L + +L + ++ + + I +A+ C +L+ L + FN +SR+ +F GL L L++ N+ H G G F + N+ LD+ N I+ S+ MF+G+ KL L L N + I AFEGL L L+L N
Sbjct: 193 IFKELEALKSLKM---QRN---GITKLMDGALFGLDNMEELELEHNNLTELNKGWLYGLHMLRVLRVSQNNIGLIRADAWEFCHRLEELDLSFNHLSRLEDWAFTGLGLLQTLNVGENRLTHL---GEGVFSGLANVHTLDIRNNDISLAIEDSVGMFVGMKKLNTLILQKNKIRTITKRAFEGLGELEQLDLSKN 379
BLAST of SMED30024248 vs. Ensembl Cavefish
Match: lrig3 (leucine rich repeats and immunoglobulin like domains 3 [Source:NCBI gene;Acc:103037077]) HSP 1 Score: 70.0922 bits (170), Expect = 3.303e-12 Identity = 68/216 (31.48%), Postives = 107/216 (49.54%), Query Frame = 2
Query: 374 LTFFNYCKVGILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQL-----KIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNG-FREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYL 1003
LTF ++ LK+ + I + M L+ + I + N+L+ V+ + +L GL L+QL I IK D+W CQ + + L + QL ++ +F+ L+ L+I N++S I+ +F+GL L L L N+ + NG F + NL KL L NRI +++ K F GL L+QL L+NN + I AF + L L
Sbjct: 218 LTFHGLHRLRSLKMQRNGIT-RLMDGAFWGLSNMEILQLEYNNLTEVS---KGWLYGLLTLQQLHLAHNAISRIKPDAWE-----FCQKLAELDLNSNQLARLEEGSFMGLSVLEQLSIGHNRVSFIADGAFRGLSLLNTLDLKYNEISWTIEDMNGPFSALNNLRKLFLQGNRIRSVTKKSFTGLDLLEQLDLSNNAIMSIQGNAFSQMKKLEEL 424 HSP 2 Score: 59.3066 bits (142), Expect = 8.877e-9 Identity = 49/152 (32.24%), Postives = 78/152 (51.32%), Query Frame = 2
Query: 677 AFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLN-PIKA--NLIKIFISADSIQCVEMKS 1123
AF ++IL + +N ++ +S GL L L L+ N + F + L +LDL+ N++A L F+GL L+QL + +N + FI + AF GL L L+L +N I + + +N P A NL K+F+ + I+ V KS
Sbjct: 243 AFWGLSNMEILQLEYNNLTEVSKGWLYGLLTLQQLHLAHNAISRIKPDAWEFCQ--KLAELDLNSNQLARLEEGSFMGLSVLEQLSIGHNRVSFIADGAFRGLSLLNTLDLKYNE--ISWTIEDMNGPFSALNNLRKLFLQGNRIRSVTKKS 390
BLAST of SMED30024248 vs. Ensembl Cavefish
Match: mxra5a (matrix-remodeling-associated protein 5 [Source:NCBI gene;Acc:103036656]) HSP 1 Score: 68.1662 bits (165), Expect = 1.594e-11 Identity = 53/174 (30.46%), Postives = 90/174 (51.72%), Query Frame = 2
Query: 695 QLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL-------LHNPKLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPKSVQKVFYSSN----DCQ 1183
Q++ + + FN ++RI+ SF G++ L L + N H NG FR++ +L + +S+N++ +S F GL L +LHL++N LEFI AF+GL SL L L LH +L P+ + L +++S + + + K L+ P ++ +F N DC+
Sbjct: 50 QVERMNLGFNTMNRITDSSFAGMRKLELLMMHGNDI-HNIPNG-AFRDLISLQMMKVSYNKLKIISRNTFQGLWNLARLHLDHNRLEFIHPDAFQGLTSLRLLQLEGNRLQQLHPATFATLSVLGHFPV-STLKHLYLSENGLTSLSQK-MLAGMPH-LENLFLHENPWVCDCR 218
BLAST of SMED30024248 vs. Ensembl Cavefish
Match: mxra5a (matrix-remodeling-associated protein 5 [Source:NCBI gene;Acc:103036656]) HSP 1 Score: 68.1662 bits (165), Expect = 1.598e-11 Identity = 53/174 (30.46%), Postives = 90/174 (51.72%), Query Frame = 2
Query: 695 QLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL-------LHNPKLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPKSVQKVFYSSN----DCQ 1183
Q++ + + FN ++RI+ SF G++ L L + N H NG FR++ +L + +S+N++ +S F GL L +LHL++N LEFI AF+GL SL L L LH +L P+ + L +++S + + + K L+ P ++ +F N DC+
Sbjct: 58 QVERMNLGFNTMNRITDSSFAGMRKLELLMMHGNDI-HNIPNG-AFRDLISLQMMKVSYNKLKIISRNTFQGLWNLARLHLDHNRLEFIHPDAFQGLTSLRLLQLEGNRLQQLHPATFATLSVLGHFPV-STLKHLYLSENGLTSLSQK-MLAGMPH-LENLFLHENPWVCDCR 226
BLAST of SMED30024248 vs. Ensembl Cavefish
Match: mxra5a (matrix-remodeling-associated protein 5 [Source:NCBI gene;Acc:103036656]) HSP 1 Score: 68.1662 bits (165), Expect = 1.610e-11 Identity = 53/174 (30.46%), Postives = 90/174 (51.72%), Query Frame = 2
Query: 695 QLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL-------LHNPKLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPKSVQKVFYSSN----DCQ 1183
Q++ + + FN ++RI+ SF G++ L L + N H NG FR++ +L + +S+N++ +S F GL L +LHL++N LEFI AF+GL SL L L LH +L P+ + L +++S + + + K L+ P ++ +F N DC+
Sbjct: 58 QVERMNLGFNTMNRITDSSFAGMRKLELLMMHGNDI-HNIPNG-AFRDLISLQMMKVSYNKLKIISRNTFQGLWNLARLHLDHNRLEFIHPDAFQGLTSLRLLQLEGNRLQQLHPATFATLSVLGHFPV-STLKHLYLSENGLTSLSQK-MLAGMPH-LENLFLHENPWVCDCR 226
BLAST of SMED30024248 vs. Ensembl Sea Lamprey
Match: lrig3 (leucine-rich repeats and immunoglobulin-like domains 3 [Source:NCBI gene;Acc:564554]) HSP 1 Score: 77.0258 bits (188), Expect = 2.906e-15 Identity = 68/218 (31.19%), Postives = 109/218 (50.00%), Query Frame = 2
Query: 374 LTFFNYCKVGILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLK-----IENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNG-FREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
L+FF + L++ ++I G+ M L L I N+L+ V + +L GL+ L+QL + I LD+W CQ ++ + L + L I+ FV L+ L + N +S I+ +FK L+ L L L+ N+ + +G F + NL KL LS N+I +++ K FIGL +L L L+NN L I + +F L +L + L
Sbjct: 106 LSFFGLESLQSLRLQRNNI-GRLMDGAFWRLEKLEILHLDFNALTNVT---KGWLYGLSSLQQLNMSHNNVSRIDLDAWE-----FCQKLDELDLSHNHLSRIEEGTFVGLGMLRSLLLAHNHLSNIADGAFKELRSLLTLDLAGNEISWTIEDMHGAFTGLENLNKLVLSENKIKSIAKKAFIGLERLHSLDLSNNALMSIQDGSFSSLKALTEMRL 314
BLAST of SMED30024248 vs. Ensembl Sea Lamprey
Match: lrig3 (leucine-rich repeats and immunoglobulin-like domains 3 [Source:NCBI gene;Acc:564554]) HSP 1 Score: 72.7886 bits (177), Expect = 5.831e-14 Identity = 60/187 (32.09%), Postives = 89/187 (47.59%), Query Frame = 2
Query: 491 QKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNG-FREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLC 1048
Q N L+ V+ +L GL L+ L + + + SE C+++ + L + L ++ AFV L+ L++ N IS I +F+GL L L L NQ + G F + L KL L N+I +++ K F+GL +L QL L N + I AF L LLH KL +LLC
Sbjct: 99 QHNRLTEVS---TGWLYGLQSLRHLHVSRNAITAMDSEAWKFCENLWELDLSHNGLTRLNEAAFVELGALQSLSLAHNAISHIVEGAFRGLSSLRILDLGGNQISWTVEDMQGAFTGLSALSKLSLHGNQIKSIAKKAFVGLERLGQLDLMGNAIVSIQANAFN------TLKLLHQMKLNTSELLC 276
BLAST of SMED30024248 vs. Ensembl Sea Lamprey
Match: LRRTM4 (leucine rich repeat transmembrane neuronal 4 [Source:HGNC Symbol;Acc:HGNC:19411]) HSP 1 Score: 66.2402 bits (160), Expect = 7.541e-12 Identity = 49/145 (33.79%), Postives = 72/145 (49.66%), Query Frame = 2
Query: 656 LENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNN--------------DLEFID----------NMAFEGLISLVYLNLLHN 1018
L+ +++ F + QL L + N + + +F+G++ L L LSSN+ + NG FR I NL LDLS+N++ L +F GL KLQ LHL +N +LEF+D AF GL L L++ HN
Sbjct: 76 LQELNYNQFASFRQLTWLYLDHNYVHTVDAHAFQGIRRLKELILSSNRISNLA-NGT-FRPISNLRNLDLSYNQLQILDPDLFRGLRKLQSLHLRSNTIKTMPVRIFQDCRNLEFLDLGYNRLRSLARNAFAGLTRLTELHMEHN 218 HSP 2 Score: 56.6102 bits (135), Expect = 7.435e-9 Identity = 53/211 (25.12%), Postives = 101/211 (47.87%), Query Frame = 2
Query: 392 CKVGILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENF--LSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
CK + + +S+ K + +N+ + GT SL +L N+ + +L L +++ + + + + ++ +IL + ++ N+ F L+ L + +NQ+ + F+GL+ L L L SN + T F++ NL LDL +NR+ +L+ F GL +L +LH+ +N ++ F L+SL +L L N
Sbjct: 41 CKCDVKIVYCESLGLKGLPRNISA-------GTLGLSLRYNSLQELNYNQFASFRQLTWLYLDHNYVHTVDAHAFQGIRRLKELILSSNRISNLANGTFRPISNLRNLDLSYNQLQILDPDLFRGLRKLQSLHLRSNTIK--TMPVRIFQDCRNLEFLDLGYNRLRSLARNAFAGLTRLTELHMEHNQFSKVNFAHFPRLMSLRHLYLQGN 242
BLAST of SMED30024248 vs. Ensembl Sea Lamprey
Match: LRRTM4 (leucine rich repeat transmembrane neuronal 4 [Source:HGNC Symbol;Acc:HGNC:19411]) HSP 1 Score: 65.0846 bits (157), Expect = 1.927e-11 Identity = 53/168 (31.55%), Postives = 86/168 (51.19%), Query Frame = 2
Query: 527 ENFLSGLNKLKQLKIEN--IKLDSWSSEYLSVCQSVEIIILKN--LQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
EN SGL +L L +++ I+L + ++ + E+ + N ++L N F VN ++ L I FNQ+ + F+GL+ L +L + SNQ T F++ ++ LDL +NR+ L+ F GL +L +LHL +N ++ F LISL L L N
Sbjct: 76 ENHFSGLKQLTWLYLDHNHIQLVA-EGAFVGARRLKELTLSSNKLIRLPNATFHPLVN---MRSLDISFNQLQMLEAGQFRGLRKLQYLHMRSNQLR--TVPVRIFQDCRSIELLDLGYNRLRVLARNAFTGLGRLTELHLEHNQFAKLNLAHFPRLISLRTLYLQWN 237 HSP 2 Score: 53.5286 bits (127), Expect = 8.899e-8 Identity = 48/190 (25.26%), Postives = 87/190 (45.79%), Query Frame = 2
Query: 620 QSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPKSVQKVFYSSNDCQSP 1189
+ ++ + +++ QL + F +C +++L + +N++ ++ +F GL LT L L NQ N F + +L L L +NRI+ L M LQ L L+ N+++ I F+GL L L L N +L ++ L + ++ +S QC + ++ + S Q C SP
Sbjct: 155 RKLQYLHMRSNQLRTVPVRIFQDCRSIELLDLGYNRLRVLARNAFTGLGRLTELHLEHNQFAKL--NLAHFPRLISLRTLYLQWNRISVLMQGMAWTWSSLQTLDLSGNEIQLIGPGFFQGLSKLHNLRLDSN-RLAAVSSETMSAWTG-LSSLNLAGNSWQCNQNICSIAIWLNSFQGTQEGVMRCGSP 340 HSP 3 Score: 51.9878 bits (123), Expect = 2.375e-7 Identity = 38/121 (31.40%), Postives = 60/121 (49.59%), Query Frame = 2
Query: 656 LENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
L+++ F QL L + N I ++ +F G + L L+LSSN+ F + N+ LD+SFN++ L F GL KLQ LH+ +N L + F+ S+ L+L +N
Sbjct: 71 LKSLPENHFSGLKQLTWLYLDHNHIQLVAEGAFVGARRLKELTLSSNKLIRLPNAT--FHPLVNMRSLDISFNQLQMLEAGQFRGLRKLQYLHMRSNQLRTVPVRIFQDCRSIELLDLGYN 189
BLAST of SMED30024248 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004554.1 (pep scaffold:Pmarinus_7.0:GL476584:51477:255513:-1 gene:ENSPMAG00000004069.1 transcript:ENSPMAT00000004554.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 58.151 bits (139), Expect = 4.247e-10 Identity = 44/117 (37.61%), Postives = 62/117 (52.99%), Query Frame = 2
Query: 671 FEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNP 1021
F+ VN L+ L + NQ+S + + F L LT+L L NQ + F +GNL +L L N++ AL +F LV LQ+L L NN L+ I AF+ L SL ++ L NP
Sbjct: 73 FDRLVN---LQKLYLWGNQLSALPVGVFDKLTQLTYLGLYVNQLKSVPRGL--FDGLGNLQQLYLRANQLTALPAGVFDRLVNLQELTLYNNQLKSIPRGAFDNLKSLTHIWLFGNP 184
BLAST of SMED30024248 vs. Ensembl Nematostella
Match: EDO48179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK32]) HSP 1 Score: 63.1586 bits (152), Expect = 1.874e-10 Identity = 55/183 (30.05%), Postives = 90/183 (49.18%), Query Frame = 2
Query: 494 KNSLSGVALDIENFLS-------GLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQ---LENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNG-FREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
+N L + LD NF + GL L+ L +++ ++ + + + +S ++ NL+ L +I F + LK+L + N+I IS SF L+ L L LS+N NG FR + NL L L NRI A++ F+GL ++ L+L+ N + I +F+G+ L L L
Sbjct: 294 QNKLQQLYLDRNNFTAIQTSSFFGLRDLQNLYLQSNQISTIITTKFADWRSFPVLRKLNLERNRLSHIQDTTFKHLLALKVLNLANNRIYHISQGSFSDLRSLEGLDLSNNDISWTVEEMNGPFRGLTNLASLRLDGNRITAIAATAFLGLENIKYLNLSANIITSIQENSFQGMDKLQKLWL 476 HSP 2 Score: 52.373 bits (124), Expect = 3.898e-7 Identity = 56/176 (31.82%), Postives = 84/176 (47.73%), Query Frame = 2
Query: 494 KNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEH-FTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
KN L+ V D LS L LK+L + S + + S+E++ L ++ I AF +L+ L + N + I SF GL+ L +L L SNQ TT +R L KL+L NR++ + F L+ L+ L+L NN + I +F L SL L+L +N
Sbjct: 233 KNRLTSVPSDA---LSQLQSLKRLDLSRNFFTSILASAFNRLSSLEVLKLSKNRISTIR-GAFWGQNKLQQLYLDRNNFTAIQTSSFFGLRDLQNLYLQSNQISTIITTKFADWRSFPVLRKLNLERNRLSHIQDTTFKHLLALKVLNLANNRIYHISQGSFSDLRSLEGLDLSNN 404
BLAST of SMED30024248 vs. Ensembl Nematostella
Match: EDO31669 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXA1]) HSP 1 Score: 53.5286 bits (127), Expect = 1.734e-7 Identity = 55/208 (26.44%), Postives = 91/208 (43.75%), Query Frame = 2
Query: 530 NFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISL----VYLNLLH---------NPKL--IVFDLLCL----NPIKANLIKIFISAD 1096
+F GLN ++ L + + ++ + L+ ++ I+F AF N L+ L + N++ R++ F L YL LSL N+ T + F + +L +L L N+I + F L L L+L++N L I GL ++ VY N L NP+L IV+D+ L P AN++ + D
Sbjct: 89 DFFLGLNNIRTLDLSGNRFSKIRFNTFGYLPGMKKLNLRRNGIKEIEFGAFRNLTALESLILSKNKLRRLTYAMFDTLSYLRLLSLVDNRLTGLTR--SMFSGLKSLRELYLQRNQIQDIEPWTFTSLKSLASLYLDSNQLTVISRDTLLGLTNVKDIHVYFNKLRYVARDAFKPNPQLTRIVWDVPALFRRTRPEFANMVGNMLHCD 294
BLAST of SMED30024248 vs. Ensembl Medaka
Match: lgr4 (leucine rich repeat containing G protein-coupled receptor 4 [Source:NCBI gene;Acc:101167435]) HSP 1 Score: 67.3958 bits (163), Expect = 2.671e-11 Identity = 57/180 (31.67%), Postives = 88/180 (48.89%), Query Frame = 2
Query: 530 NFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNG-FREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKA 1066
N +++L++ L E LS +++++L+N QL+++ A N L+ L + N I+ + SF+GL+ L HL L N H T G NL L L+ NRI + F L L LHL+NN + I + +F GL++L L+L N L+VF PI+A
Sbjct: 74 NVFKSFPYMEELRLAGNDLTFIHPEALSGLHQLKVLMLQNNQLKSVPSAALKNLQSLQSLRLDANHITTVPDESFQGLQQLRHLWLDDN---HLTQVPVGSLTHQANLQALTLALNRITYIPANAFANLTSLVVLHLHNNRIREIASNSFAGLVNLETLDLNFN-NLMVFP----KPIEA 245
BLAST of SMED30024248 vs. Ensembl Medaka
Match: lgr4 (leucine rich repeat containing G protein-coupled receptor 4 [Source:NCBI gene;Acc:101167435]) HSP 1 Score: 67.0106 bits (162), Expect = 2.970e-11 Identity = 57/181 (31.49%), Postives = 88/181 (48.62%), Query Frame = 2
Query: 527 ENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNG-FREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKA 1066
N +++L++ L E LS +++++L+N QL+++ A N L+ L + N I+ + SF+GL+ L HL L N H T G NL L L+ NRI + F L L LHL+NN + I + +F GL++L L+L N L+VF PI+A
Sbjct: 73 ANVFKSFPYMEELRLAGNDLTFIHPEALSGLHQLKVLMLQNNQLKSVPSAALKNLQSLQSLRLDANHITTVPDESFQGLQQLRHLWLDDN---HLTQVPVGSLTHQANLQALTLALNRITYIPANAFANLTSLVVLHLHNNRIREIASNSFAGLVNLETLDLNFN-NLMVFP----KPIEA 245
BLAST of SMED30024248 vs. Ensembl Medaka
Match: lrrtm4l1 (leucine-rich repeat transmembrane neuronal protein 4-like [Source:NCBI gene;Acc:101154965]) HSP 1 Score: 65.0846 bits (157), Expect = 9.584e-11 Identity = 69/226 (30.53%), Postives = 106/226 (46.90%), Query Frame = 2
Query: 596 SSEYLSVCQSVEI----IILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNN--------------DLEFID----------NMAFEGLISLVYLNLLHNP-KLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPKSVQKVFYSSNDCQS 1186
SS +L V +++ + + L+ +L + F + Q+ + + NQIS I +F+G++ L L LSSN+ + + + F I NL LDLSFN++ L F GL KLQ LHL +N LEF+D F GL L+ L+L HN I F L P ANL +++ + I+ V L ++QK+ S N+ Q+
Sbjct: 67 SSGFLEVPENISVGCQGLSLRYNELHTLLPYQFAHLSQILWIYLDHNQISAIDSRAFQGVRRLKELILSSNRIT--SLHNSTFHGIPNLRSLDLSFNKLEILQPGQFHGLRKLQNLHLRSNGLSNIPIRVFLECRSLEFLDLGYNRIKALTRTTFLGLQRLMELHLEHNQFTRINFFLF---PRLANLRSLYLQWNRIRVV--NQGLPWIWYTLQKLDLSGNEIQT 285 HSP 2 Score: 59.6918 bits (143), Expect = 4.784e-9 Identity = 57/182 (31.32%), Postives = 83/182 (45.60%), Query Frame = 2
Query: 635 IILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCE----------------HFTTNG------NGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKANLIKIFISADSIQCVE 1114
I L + Q+ ID AF +LK L + N+I+ + +F G+ L L LS N+ E H +NG F E +L LDL +NRI AL+ F+GL +L +LHL +N I+ F L +L L L N +V L I L K+ +S + IQ ++
Sbjct: 108 IYLDHNQISAIDSRAFQGVRRLKELILSSNRITSLHNSTFHGIPNLRSLDLSFNKLEILQPGQFHGLRKLQNLHLRSNGLSNIPIRVFLECRSLEFLDLGYNRIKALTRTTFLGLQRLMELHLEHNQFTRINFFLFPRLANLRSLYLQWNRIRVVNQGLPW--IWYTLQKLDLSGNEIQTLD 287
BLAST of SMED30024248 vs. Ensembl Medaka
Match: lrrtm4l1 (leucine-rich repeat transmembrane neuronal protein 4-like [Source:NCBI gene;Acc:101154965]) HSP 1 Score: 65.0846 bits (157), Expect = 1.093e-10 Identity = 67/225 (29.78%), Postives = 106/225 (47.11%), Query Frame = 2
Query: 596 SSEYLSVCQSVEI----IILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNN--------------DLEFID----------NMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPKSVQKVFYSSNDCQS 1186
SS +L V +++ + + L+ +L + F + Q+ + + NQIS I +F+G++ L L LSSN+ + + + F I NL LDLSFN++ L F GL KLQ LHL +N LEF+D F GL L+ L+L HN + + L P ANL +++ + I+ V L ++QK+ S N+ Q+
Sbjct: 67 SSGFLEVPENISVGCQGLSLRYNELHTLLPYQFAHLSQILWIYLDHNQISAIDSRAFQGVRRLKELILSSNRIT--SLHNSTFHGIPNLRSLDLSFNKLEILQPGQFHGLRKLQNLHLRSNGLSNIPIRVFLECRSLEFLDLGYNRIKALTRTTFLGLQRLMELHLEHN-QFTRINFF-LFPRLANLRSLYLQWNRIRVV--NQGLPWIWYTLQKLDLSGNEIQT 285 HSP 2 Score: 59.3066 bits (142), Expect = 5.994e-9 Identity = 57/182 (31.32%), Postives = 83/182 (45.60%), Query Frame = 2
Query: 635 IILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCE----------------HFTTNG------NGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKANLIKIFISADSIQCVE 1114
I L + Q+ ID AF +LK L + N+I+ + +F G+ L L LS N+ E H +NG F E +L LDL +NRI AL+ F+GL +L +LHL +N I+ F L +L L L N +V L I L K+ +S + IQ ++
Sbjct: 108 IYLDHNQISAIDSRAFQGVRRLKELILSSNRITSLHNSTFHGIPNLRSLDLSFNKLEILQPGQFHGLRKLQNLHLRSNGLSNIPIRVFLECRSLEFLDLGYNRIKALTRTTFLGLQRLMELHLEHNQFTRINFFLFPRLANLRSLYLQWNRIRVVNQGLPW--IWYTLQKLDLSGNEIQTLD 287
BLAST of SMED30024248 vs. Ensembl Medaka
Match: ENSORLT00000041850.1 (leucine rich repeat containing G protein-coupled receptor 5 [Source:NCBI gene;Acc:101157030]) HSP 1 Score: 65.0846 bits (157), Expect = 1.132e-10 Identity = 52/173 (30.06%), Postives = 83/173 (47.98%), Query Frame = 2
Query: 500 SLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHN 1018
S++ + L LS L+ L++L++ L + ++++++L+N QL ++ EAF N L+ L + N IS + SF GL+ L HL L N E+ L + L+ N I + F L +L LHLNNN + + F GL SL L+L +N
Sbjct: 85 SMNNMTLISAGALSSLHFLQELRLPGNDLSFIPKGAFAGLYNLKVLMLQNNQLRSVPAEAFNNLHNLQSLRLDANHISGVPAGSFSGLRSLRHLWLDDNALTEVPA--EALSELPALQAMTLALNHIRHVPDHAFSALGRLVVLHLNNNRIVSMGTNCFHGLHSLETLDLNYN 255 HSP 2 Score: 53.1434 bits (126), Expect = 6.992e-7 Identity = 52/195 (26.67%), Postives = 88/195 (45.13%), Query Frame = 2
Query: 425 SIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNL 1009
S+P + NL +L L +D N +SGV SGL L+ L +++ L +E LS +++ + L + ++ AF +L +L + N+I + F GL L L L+ NQ F T R + +L +L N+I ++ F G L + +N ++ + AF+ L L L+L
Sbjct: 139 SVPA-EAFNNLHNLQSLRLDA---NHISGVP---AGSFSGLRSLRHLWLDDNALTEVPAEALSELPALQAMTLALNHIRHVPDHAFSALGRLVVLHLNNNRIVSMGTNCFHGLHSLETLDLNYNQLMEFPT---AIRSLRHLKELGFHSNKIQSIPDHAFTGNPSLTTVFFYDNPIQSVGRTAFQNLPELRTLSL 323
BLAST of SMED30024248 vs. Planmine SMEST
Match: SMESG000055844.1 (SMESG000055844.1) HSP 1 Score: 850.507 bits (2196), Expect = 0.000e+0 Identity = 442/460 (96.09%), Postives = 444/460 (96.52%), Query Frame = 2
Query: 146 MYIVQFLSAIITIELWRFTLARIPCPQKLCRCDENGQPWKCEIRRDQDQIDCSQDLSLSEPINVNLNLINFTYQRKLTFFNYCKVGILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPKSVQKVFYSSNDCQSPSEMTRHTTTVSETLPLKAGSPNXXXXXXXXXXXXXXXXGIFVGVFTGCSMKKKIRKYKNSCSDRLTSHSNSLRNYDPYPGNHTIPNHLPLLNETPKLSPRYRSNPILSNTSV 1525
MYIVQFLSAIITIELWRFTLAR+PCPQKLCRCDENGQPWKCEIRRDQDQIDCSQDLSLSEPINVNLNLINFTYQRKLTFFNYCKVGILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAF ISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLS NRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLL+NPKLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPKSVQKVFYSSNDCQSPSEMTRHTTTVSETLPLKAGSPNMVLIVVVAVAVTLLMVGIFVGVFTGCSMKKKIRKYKNSCSDRLTSHSNSLRNYDPYPGNHTIPNHLPLLNETPKLSPRYRSNPILSNTSV
Sbjct: 1 MYIVQFLSAIITIELWRFTLARVPCPQKLCRCDENGQPWKCEIRRDQDQIDCSQDLSLSEPINVNLNLINFTYQRKLTFFNYCKVGILKISSDSIPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIENFLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAF---------------ISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSSNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLNNPKLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPKSVQKVFYSSNDCQSPSEMTRHTTTVSETLPLKAGSPNMVLIVVVAVAVTLLMVGIFVGVFTGCSMKKKIRKYKNSCSDRLTSHSNSLRNYDPYPGNHTIPNHLPLLNETPKLSPRYRSNPILSNTSV 445
BLAST of SMED30024248 vs. Planmine SMEST
Match: SMESG000052792.1 (SMESG000052792.1) HSP 1 Score: 57.3806 bits (137), Expect = 1.614e-8 Identity = 86/320 (26.88%), Postives = 140/320 (43.75%), Query Frame = 2
Query: 215 PCPQKLCRCDENGQPWKCEIRR-DQDQIDCSQDLSLSEPINVNLNLINFTYQRKLTF----FNYC-KVGILKISSDS---IPGKQMIKNLESLNYLIIDGTQKNSLSGVALDIEN-FLSGLNKLKQLKIENIKLDSWSSEYLSVCQSVEIIILKNLQLENIDFEAFVNCFQLKILTIIFNQISRISILSFKGLKYLTHLSLSSNQCEHFTTNGNGFREIGNLIKLDLSFNRIAALSMKMFIGLVKLQQLHLNNNDLEFIDNMAFEGLISLVYLNLLHNPKLIVFDLLCLNPIKANLIKIFISADSIQCVEMKSKLSDFPK 1144
PC QK CRC + K E+ D+ D ++ PI + +KL F C ++ L I+++S + QM K + L L++ + IEN FL LK L I +++ S S C E I L + ++ I + F +C ++ L + N+++ I L F L +L LS N+ F+ + + L+L+ N + + ++ GL LQ L L+ N +E I+ AF L SL Y+NL NP L +L L NL + + ++CV+ + SD+ K
Sbjct: 31 PC-QKKCRCKHKEKSSKIEVAHCTVDEKDTFVSCNVEWPILL-------MTVKKLRFNADLLAACQRISGLLITTESSLIVLMPQMFKLVSRLETLVVQAPIQT--------IENQFLKNFVSLKILHISETRIEHLSRGMFSDCPITERIRLSSNRISVIADKTFDSCNRVVNLDLGNNRLTVIRRLIFNEGHSLQNLDLSRNRITRI--EDFSFKNLKKMKVLNLNANLLMRIKPEILFGLESLQYLFLSKNSIETIEEDAFVNLKSLKYINLEKNPLLRPNMVLFL-----NLDNLTVLLTGVKCVD--EQYSDYSK 325 The following BLAST results are available for this feature:
BLAST of SMED30024248 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SMED30024248 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 4
BLAST of SMED30024248 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of SMED30024248 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SMED30024248 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SMED30024248 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SMED30024248 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SMED30024248 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SMED30024248 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SMED30024248 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of SMED30024248 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of SMED30024248 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of SMED30024248 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SMED30024248 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024248 ID=SMED30024248|Name=SMED30024248|organism=Schmidtea mediterranea sexual|type=transcript|length=1592bpback to top protein sequence of SMED30024248-orf-1 >SMED30024248-orf-1 ID=SMED30024248-orf-1|Name=SMED30024248-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=461bp MYIVQFLSAIITIELWRFTLARIPCPQKLCRCDENGQPWKCEIRRDQDQIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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