Innexin

Overview
NameInnexin
Smed IDSMED30024236
Length (bp)1649
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30024236) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30024236) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30024236) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30024236) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30024236

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30024236h1SMcG0001022 Contig5492GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30024236h1SMcG0001022 AY967558smed_ncbi_20240424PMID:17670787
Oviedo et al., 2007		whole organism asexual adult colorimetric in situ hybridization evidence
Smed sexual biotypeSMED30024236h1SMcG0001022 Contig39758newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30024236h1SMcG0001022 Contig39758uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30024236h1SMcG0001022 dd_Smed_v4_734_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30024236h1SMcG0001022 dd_Smed_v4_734_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30024236h1SMcG0001022 dd_Smed_v4_734_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30024236h1SMcG0001022 dd_Smed_v6_734_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393])

HSP 1 Score: 274.633 bits (701), Expect = 4.344e-87
Identity = 150/388 (38.66%), Postives = 235/388 (60.57%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWL-LRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKM 1514
            +N++YT+ ++ + AI +S KQY+   I CW+P  F++P  QY ENYCW+QNTY++P    +P ++  R   Q+ YYQWVP+VLAL+  LFY P   WRL++WQSGI++Q L+  A   C +   D++       N A +     ++E             A H++  + S +  K      + +L+ C   +R  G  +  LYI  K+LY +N+VGQ+FLLN+F+G   K +G Q+L +L  G +W+ +GHFPR+TLCDFE++ LG    +TVQCVL IN+FNEKI++F+WFW F++A  ++ SLF W+ + ++ S++  F+   L   ++ +   D+  L+RF+   L+ DGVFL+ ++  +AG+L   EL   +W  Y    E KM
Sbjct:   27 LNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMA---CDSRLLDLE-----SRNRALQTIATNVEE-------------ALHVKHQVMSGNRLK------LLNLIIC---TRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTG-IEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGKM 383
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 267.7 bits (683), Expect = 2.159e-84
Identity = 148/381 (38.85%), Postives = 227/381 (59.58%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWR-LMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSW-LLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRY 1490
            +N+ YTS ++   AI +S KQY+   I CW+P +F+  W QY ENYCW++NTYY+P  +  P  +G R   Q+SYYQWVP+VLAL+   FY P   WR L++W SGIN+Q L   A +          +    D   A+ +T     ED   E+ +E+ D++    + +Q                       +++  Y+  LY+F K+LY+ NVV Q+F+LNSF+GT    +GF +L +L  G +W+ +G+FPR+T+CDFE+R LG   ++TVQCVL IN+FNEKI++F+WFW F+VA +S  S+F W ++  +  Q  KFI+  L  R  + + TD   +K+F+ + L  DGVF + +I  +AGD++  EL+  +W+ +
Sbjct:   25 LNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDA---------RMMDADARAATVQTIAGHMED-ALEIQREVTDVS---GMCVQ-----------------------KRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYL--RATDLA-TDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF 366
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 267.7 bits (683), Expect = 2.159e-84
Identity = 148/381 (38.85%), Postives = 227/381 (59.58%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWR-LMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSW-LLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRY 1490
            +N+ YTS ++   AI +S KQY+   I CW+P +F+  W QY ENYCW++NTYY+P  +  P  +G R   Q+SYYQWVP+VLAL+   FY P   WR L++W SGIN+Q L   A +          +    D   A+ +T     ED   E+ +E+ D++    + +Q                       +++  Y+  LY+F K+LY+ NVV Q+F+LNSF+GT    +GF +L +L  G +W+ +G+FPR+T+CDFE+R LG   ++TVQCVL IN+FNEKI++F+WFW F+VA +S  S+F W ++  +  Q  KFI+  L  R  + + TD   +K+F+ + L  DGVF + +I  +AGD++  EL+  +W+ +
Sbjct:   25 LNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDA---------RMMDADARAATVQTIAGHMED-ALEIQREVTDVS---GMCVQ-----------------------KRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYL--RATDLA-TDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF 366
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 266.159 bits (679), Expect = 2.557e-83
Identity = 150/381 (39.37%), Postives = 227/381 (59.58%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWR-LMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSW-LLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRY 1490
            +N+ YTS ++   AI +S KQY+   I CW+P +F+  W QY ENYCW++NTYY+P  +  P  +G R   Q+SYYQWVP+VLAL+   FY P   WR L++W SGIN+Q L   A   C     D       D   A+ +T     ED   E+ +E+ D++    + +Q                       +++  Y+  LY+F K+LY+ NVV Q+F+LNSF+GT    +GF +L +L  G +W+ +G+FPR+T+CDFE+R LG   ++TVQCVL IN+FNEKI++F+WFW F+VA +S  S+F W ++  +  Q  KFI+  L  R  + + TD   +K+F+ + L  DGVF + +I  +AGD++  EL+  +W+ +
Sbjct:   25 LNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPLEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMA---CDARMMDA------DARAATVQTIAGHMED-ALEIQREVTDVS---GMCVQ-----------------------KRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYL--RATDLA-TDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF 366
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-13 (Innexin [Source:UniProtKB/TrEMBL;Acc:O44887])

HSP 1 Score: 255.758 bits (652), Expect = 8.160e-80
Identity = 142/382 (37.17%), Postives = 223/382 (58.38%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLR-MIASQRFKFIQGLL--EKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRY 1490
            +N+++T ++LVI A+ +S KQY+   I CW+P +F+  W QY+ENYC++QNTY+I  D  +P S   R  +++ YYQWVP++L LQ  LFY P  FWRLMN+ SG+ ++ ++  A            +      N+A+K T   + E                  L++QS       FAK   +  +        G YL  LY+F K LY++ +V Q  +LN+F+GTSY  +G  +L ++  G +W+ +GHFPR+T+CDFE+R LG +  +TVQCVL IN+FNEK+Y+F+WFW+ IV + +  +L +W  + M  S R   I+  L  E    + ++ +   L +F+D  LK+DGVF+ +LI  N G + + +++  MW R+
Sbjct:   23 LNYYWTPMLLVIFALTLSAKQYVGQPIQCWIPAQFTGAWEQYSENYCFVQNTYFISPDKYIPDSEIDREGAEIGYYQWVPFILGLQAILFYLPSLFWRLMNFNSGVALKKMLFGA--------KKADRVDEKARNEAAKSTGAHLYE-----------------SLTLQSR------FAKYTSAFTYG-------GSYLTYLYLFVKFLYLVQIVFQFIILNNFLGTSYTFWGLGILSDILNGREWEESGHFPRVTMCDFEVRVLGNKHRHTVQCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHIKSYLQIEDNFSDDNSRNGQILDKFVDYKLKSDGVFITHLIDNNGGSVFSHDVIVDMWDRF 366
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860)

HSP 1 Score: 72.0182 bits (175), Expect = 2.688e-13
Identity = 93/383 (24.28%), Postives = 163/383 (42.56%), Query Frame = 3 
Query:  369 TSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPH--------DTELPK--SH--GYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQML-FNLAKGNDWKN--TGHFPRITLCDFEIRN-LGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELL 1469
            T I+L+  ++ ++++QY+ D I C +     +  +   + YCWI +T+ +P         D   P   SH  G        YYQWV +VL  Q  LFY PR  W+  +W+ G  ++ L+            D+  P  NDE    +                                        K +    F G  +R + FY    ++  + L  +NV+GQ++ ++ F+   +  +G  +L F   + ++  +     FP++T C F      G    +   CVLP+N+ NEKIY+F+WFW  I++I+S  SL  + + ++A  + + +  LL  R    S    ++    +         FL+Y +  N   L+ KE++
Sbjct:   31 TVIILIAFSLLVTSRQYIGDPIDCIV----DEIPLGVMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWK--SWEGG-RLKMLVM-----------DLNSPIVNDECKNDR----------------------------------------KKILVDYFIGNLNR-HNFYAFRFFV-CEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI-YRIAVVAGPKLRHL--LLRAR----SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVI 346
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005)

HSP 1 Score: 72.0182 bits (175), Expect = 2.688e-13
Identity = 93/383 (24.28%), Postives = 163/383 (42.56%), Query Frame = 3 
Query:  369 TSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPH--------DTELPK--SH--GYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQML-FNLAKGNDWKN--TGHFPRITLCDFEIRN-LGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELL 1469
            T I+L+  ++ ++++QY+ D I C +     +  +   + YCWI +T+ +P         D   P   SH  G        YYQWV +VL  Q  LFY PR  W+  +W+ G  ++ L+            D+  P  NDE    +                                        K +    F G  +R + FY    ++  + L  +NV+GQ++ ++ F+   +  +G  +L F   + ++  +     FP++T C F      G    +   CVLP+N+ NEKIY+F+WFW  I++I+S  SL  + + ++A  + + +  LL  R    S    ++    +         FL+Y +  N   L+ KE++
Sbjct:   31 TVIILIAFSLLVTSRQYIGDPIDCIV----DEIPLGVMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWK--SWEGG-RLKMLVM-----------DLNSPIVNDECKNDR----------------------------------------KKILVDYFIGNLNR-HNFYAFRFFV-CEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI-YRIAVVAGPKLRHL--LLRAR----SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVI 346
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0332314)

HSP 1 Score: 72.0182 bits (175), Expect = 2.688e-13
Identity = 93/383 (24.28%), Postives = 163/383 (42.56%), Query Frame = 3 
Query:  369 TSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPH--------DTELPK--SH--GYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQML-FNLAKGNDWKN--TGHFPRITLCDFEIRN-LGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELL 1469
            T I+L+  ++ ++++QY+ D I C +     +  +   + YCWI +T+ +P         D   P   SH  G        YYQWV +VL  Q  LFY PR  W+  +W+ G  ++ L+            D+  P  NDE    +                                        K +    F G  +R + FY    ++  + L  +NV+GQ++ ++ F+   +  +G  +L F   + ++  +     FP++T C F      G    +   CVLP+N+ NEKIY+F+WFW  I++I+S  SL  + + ++A  + + +  LL  R    S    ++    +         FL+Y +  N   L+ KE++
Sbjct:   31 TVIILIAFSLLVTSRQYIGDPIDCIV----DEIPLGVMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWK--SWEGG-RLKMLVM-----------DLNSPIVNDECKNDR----------------------------------------KKILVDYFIGNLNR-HNFYAFRFFV-CEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI-YRIAVVAGPKLRHL--LLRAR----SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVI 346
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071006)

HSP 1 Score: 72.0182 bits (175), Expect = 2.688e-13
Identity = 93/383 (24.28%), Postives = 163/383 (42.56%), Query Frame = 3 
Query:  369 TSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPH--------DTELPK--SH--GYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQML-FNLAKGNDWKN--TGHFPRITLCDFEIRN-LGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELL 1469
            T I+L+  ++ ++++QY+ D I C +     +  +   + YCWI +T+ +P         D   P   SH  G        YYQWV +VL  Q  LFY PR  W+  +W+ G  ++ L+            D+  P  NDE    +                                        K +    F G  +R + FY    ++  + L  +NV+GQ++ ++ F+   +  +G  +L F   + ++  +     FP++T C F      G    +   CVLP+N+ NEKIY+F+WFW  I++I+S  SL  + + ++A  + + +  LL  R    S    ++    +         FL+Y +  N   L+ KE++
Sbjct:   31 TVIILIAFSLLVTSRQYIGDPIDCIV----DEIPLGVMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWK--SWEGG-RLKMLVM-----------DLNSPIVNDECKNDR----------------------------------------KKILVDYFIGNLNR-HNFYAFRFFV-CEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI-YRIAVVAGPKLRHL--LLRAR----SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVI 346
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0112570)

HSP 1 Score: 59.3066 bits (142), Expect = 3.520e-9
Identity = 35/128 (27.34%), Postives = 60/128 (46.88%), Query Frame = 3 
Query:  369 TSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYI------PHDTELP-------KSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCT 713
            T I+L+  +I ++T+QY+ + I C    +  +        YCWI +TY +         +E+P       +  G  T     YYQWV + L  Q  LFY PR  W+  +W+ G     +++  + +C+
Sbjct:   19 TVILLITFSIAVTTRQYVGNPIDCVHTRDIPE---DVLNTYCWIHSTYTVVDAFMKKQGSEVPFPGVHNSQGRGPLTIKHTKYYQWVAFTLFFQAILFYTPRWLWK--SWEGGKIHALIMDLDIGICS 141

HSP 2 Score: 51.2174 bits (121), Expect = 1.398e-6
Identity = 28/87 (32.18%), Postives = 48/87 (55.17%), Query Frame = 3 
Query:  960 YIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGH---FPRITLCD-FEIRNLGQRTNYTVQCVLPINLFNEK 1208
            Y   +LL +INV+GQ+FL+N F    +  FG +++  +    + +       FPR+T C  F+  + G+   +   C+LP+N+ NEK
Sbjct:  170 YYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEK 256
[Close]
BLAST of Innexin vs. Ensembl Zebrafish
Match: panx1b (pannexin 1b [Source:ZFIN;Acc:ZDB-GENE-070705-192])

HSP 1 Score: 48.9062 bits (115), Expect = 8.739e-6
Identity = 46/200 (23.00%), Postives = 83/200 (41.50%), Query Frame = 3 
Query:  381 LVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVC--TTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLL--FCGFGSRKYGFYLITLYIF 968
            L+++++  + +  +   ITC+ P  F+     YA+++CW    ++ P + E         ++ L  +++ PY+L L   L Y P  FWR     S  +    I + ++ C    IR         D++         I ED  P    E+ +  +   L  Q     + S+A   + LL     F +   G + +T YIF
Sbjct:   47 LLLISLAFAQEVSVGTQITCFPPTNFTMRQAAYADSFCWAAVEHH-PSENE-------TYSAPLHLHKFFPYILLLLAILMYIPALFWRFTAAPSLSSDLSFIMEELDRCYNRAIRLAKSITTKQDKD---------IAED--PHSGLELTEACFKYPLVEQYLKTKRSSWALAAKYLLCRVLTFLTLLLGCFYLTYYIF 227
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 274.633 bits (701), Expect = 5.526e-86
Identity = 150/388 (38.66%), Postives = 235/388 (60.57%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWL-LRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKM 1514
            +N++YT+ ++ + AI +S KQY+   I CW+P  F++P  QY ENYCW+QNTY++P    +P ++  R   Q+ YYQWVP+VLAL+  LFY P   WRL++WQSGI++Q L+  A   C +   D++       N A +     ++E             A H++  + S +  K      + +L+ C   +R  G  +  LYI  K+LY +N+VGQ+FLLN+F+G   K +G Q+L +L  G +W+ +GHFPR+TLCDFE++ LG    +TVQCVL IN+FNEKI++F+WFW F++A  ++ SLF W+ + ++ S++  F+   L   ++ +   D+  L+RF+   L+ DGVFL+ ++  +AG+L   EL   +W  Y    E KM
Sbjct:   27 LNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMA---CDSRLLDLE-----SRNRALQTIATNVEE-------------ALHVKHQVMSGNRLK------LLNLIIC---TRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTG-IEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGKM 383
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 241.891 bits (616), Expect = 7.304e-72
Identity = 140/390 (35.90%), Postives = 217/390 (55.64%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWR-LMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFG-SRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRM-IASQRFKFIQGLLEKRLKNWST--TDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSET 1508
            +N++YT+ +L   A+ +S KQY+   I CW+P  F+    QY ENYCW+QNTY++P   ++P+    R   Q+ YYQWVP++LA++  LFY P   WR L+ W SGIN+Q L+  A                 D      E K            + +  MA H++  +Q  +  +   +++  S L  G    R  G Y+  LYI  K+LY  NV+ Q FLLN  +G++   +GF +L +L    +W+ TG FPR+TLCDFE+R LG    +TVQCVL IN+FNEKI++F+WFW     I++V +   W+L M I SQ   F++  L     + +    D+  L++F +  L+ DGVF++ +I  +AG+L++ EL+  +W  +  +  +
Sbjct:  145 LNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMAC----------------DARLMDSEIKT-----------RTVYTMARHMQDEVQLTNIDRQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNNVDRS 507
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|A8WVX4|INX19_CAEBR (Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=inx-19 PE=3 SV=3)

HSP 1 Score: 220.32 bits (560), Expect = 1.686e-64
Identity = 132/402 (32.84%), Postives = 212/402 (52.74%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTS-YKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLL-RMIASQRFKFIQGLLE-------KRLKNWSTTDNNQ------------LKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKK 1496
            +N++YT ++L +  + IS KQY    I CW+     +   +Y E+YCWIQNTY+IP    +P  H  R   Q+ YYQWVP++L  +  +F  P  FWRL ++QSG+NIQ LIN A +    +         +D   A +       ++++ + P                   ++G  A+    + F  F S   G  +  +Y FTKLLY +NVV Q F+LN+ + +S +  FGFQ+L ++  G  W  TGHFPR+TLCDFE+R L     YTVQC L IN+ NEK++ F+W W  I+AI++  S   W+    I S++  ++   ++       K+L+ +      +            L  F+ + LK+DG+ ++ +I  +AGD++  +L+  +W  Y++
Sbjct:   27 LNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYWIPMYENVPDDHTAREEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQTLINAACDAQALL-------DYSDRQKAVEAITCNFVDNLDLQSPN--------------GRIRARGWIAR----IKFSRFLS---GQCISIVYSFTKLLYSVNVVAQFFILNACLKSSEFVFFGFQVLSDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEYKKLQKFEKDATVERLYTVIAFAPHLLDSFVSDFLKSDGILMLRMISNHAGDMIVVQLVRNLWQEYRE 400
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O61715|INX19_CAEEL (Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=inx-19 PE=1 SV=2)

HSP 1 Score: 215.698 bits (548), Expect = 1.145e-62
Identity = 134/402 (33.33%), Postives = 210/402 (52.24%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTS-YKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWL----------------LRMIASQRFKFIQGLLE----KRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKK 1496
            +N++YT ++L +  + IS KQY    I CW+     +   +Y E+YCWIQNTY+IP    +P  H  R   Q+ YYQWVP++L  +  +F  P  FWRL ++QSG+NIQ LIN A +    +         +D   A +       ++++ + P                   ++G  A+    + F  F S   G  L  L+ FTKLLY +NVV Q  +LN+ + +S +  FGFQ+L ++  G  W  TGHFPR+TLCDFE+R L     YTVQC L IN+ NEK++ F+W W  I+AI++  S   W+                +++  S  FK +Q   +    +RL        + L  F+ + LK+DGV ++ +I  +AGD++  +L+  +W  +++
Sbjct:   43 LNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYWIPMYENVPDDHTAREEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQTLINAACDGQALL-------DASDRQKAVEAITTNFVDNLDLQSPN--------------GRIRARGWIAR----IKFSRFLS---GQCLSILHSFTKLLYSMNVVAQFLILNACLKSSDFLFFGFQVLNDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLWQEFRE 416
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2)

HSP 1 Score: 211.46 bits (537), Expect = 2.407e-61
Identity = 130/377 (34.48%), Postives = 201/377 (53.32%), Query Frame = 3 
Query:  369 TSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRM-IASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKK 1496
            T+ +L   +I +S KQY+  +I CWMP+EF   W QYAE+YC+IQNT++IP  +E+P     R  +++ YYQWVP VLA+Q F+FY P   W  +  Q G++   +I++A           +  +  D    +K            ++   I D+          ++ SK  + +      +C    +  G     LYI  KL+Y+ NV  Q  +LN F+G    L+GF    +L  G +W+++G FPR+TLCDF +R L     YTVQCVL IN+FNEKIY+FIWFW   V I +  +    + R+   S R  +I+ LL   + N+   +   +  F +  LK DGV L+  I  +AG +VTKE+ + ++ ++ +
Sbjct:   32 TATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFFIPERSEIPGDVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFPSVISEA-----------EALRSQDSETRTKGVN---------KLVDFIGDIL---------DTRSKNEYGR-----FYCYRFGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDSGVFPRVTLCDFSVRKLANVHRYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRSLLSGPVNNFK-DEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKHGE 373
[Close]
BLAST of Innexin vs. TrEMBL
Match: Q9NCL5 (Innexin OS=Girardia tigrina OX=6162 GN=Panx1 PE=2 SV=1)

HSP 1 Score: 431.795 bits (1109), Expect = 4.538e-144
Identity = 219/391 (56.01%), Postives = 299/391 (76.47%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIP-HD-TELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSL 1520
            ++H YT++ L+I +I IS+KQY+ D I CW+P EFS PW +YA NYCWI+NTY +P +D   +PK    R   +++YYQWVP VL +Q+ LFYFP   WR++NW  GINIQD+I KAM+VC+TIR   +K K +      ++ +    ++ EPEVP  I+D+A HLE+SI+    SK +F K +R+L  CGFGSRKYG YLITLY  TKLLYIINV+GQ+FLL   +    + FGF++L +L KG+DWK+TGHFPR+T+CDF+IRNLGQRTNY+VQCVLPINLFN+KIYIFIWFWIF+V+IL+VYS F W+ RM++ Q+ KFI+GLL K L  WS  DN+ L+ FI+++LK+DGVFL+YLIY+N+GD+VT +LL+V+W+R+K+ ++  + +
Sbjct:   31 LSHHYTALFLLITSILISSKQYVGDPIHCWVPKEFSDPWQKYANNYCWIKNTYTVPSYDFMSIPKPDE-RKKLEINYYQWVPIVLLIQSLLFYFPTIIWRILNWTVGINIQDMIGKAMDVCSTIRTVPEKEKNDKTESKDEKEEQSSSKEEEPEVPGIIRDIANHLEISIEFVEKSKSNFVKALRNLFVCGFGSRKYGSYLITLYFVTKLLYIINVIGQIFLLTHSLNVLVRFFGFKVLSDLGKGDDWKSTGHFPRVTMCDFQIRNLGQRTNYSVQCVLPINLFNKKIYIFIWFWIFLVSILTVYSFFHWIFRMLSFQKVKFIRGLLLKGLNKWSGGDNDLLRSFINDYLKSDGVFLMYLIYINSGDIVTTQLLEVLWFRFKQKNKDSLKI 420
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A1I8IYE0 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 292.738 bits (748), Expect = 3.930e-90
Identity = 155/407 (38.08%), Postives = 241/407 (59.21%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSK----GSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLR-MIASQRFKFIQGLLEK-----RLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSL-DSNYPEE 1541
            +NH+YT+IV+V+    IS KQY+   + CW+P +F+    QYAENYCWIQNTYY+P    +PK H +R   ++ YYQWVP++L  Q  LFY P   WRL+NW+SGIN      +A+N  T+   D Q   P+                      + I+ +A H+E +++ +   +    G   +     L C   SR++G +L  +Y   KLLYI N V Q FLLN+F+G+ Y+ FG+++L N+  G  W+ +G FPR+T+CDFEIR LG    +TVQCVL INLFNEKI++F+WFW+F+VA+ +V S F+WL +  +   R +F+   L       R  +      +QL+ F+ ++L+ DGVF++ ++ +NAG++++ E+   MW  Y+   +  +   ++N P++
Sbjct:   31 LNHYYTAIVIVVFTFIISAKQYVGQPLQCWVPAQFTTAMEQYAENYCWIQNTYYLPLRHTIPKEHSHRNDRKIGYYQWVPFMLVCQALLFYLPNIVWRLLNWESGINF-----RAINRMTS---DAQNVNPDSRG-------------------KTIRAIARHIEDALRYQKRERRDCLGQLRQAANKFLLC---SRRHGVFLSLMYFLVKLLYICNCVCQFFLLNAFLGSPYQFFGWELLINMISGVTWEESGQFPRVTMCDFEIRVLGNLHRHTVQCVLVINLFNEKIFVFLWFWLFLVAVATVMSFFTWLYKHALPPMRHQFVLSSLRMADSNVRRDSRDVAVRHQLENFVSQNLRCDGVFVLRMLAINAGEIISAEVAREMWLSYRGDCKRPLQTGNANGPDQ 407
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A267DW92 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 292.738 bits (748), Expect = 4.785e-90
Identity = 163/403 (40.45%), Postives = 239/403 (59.31%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYL-NDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSK-GSFAKTVR---SLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMS---LDSNYPE 1538
            IN +YT I+++ ++  I TK YL  D + CW+P EF   W Q+AENYCW++NTYY+P +  +P     R+  +L+YYQWVP+VLALQ  LFY P A W+L+NWQSGI+I DL++ A+N                             ED E +  +++  +  H+EL+I  +   K G   +T R    +LFCG+   K G YL  +Y+  KLL+I NVVGQ FLLNSF+GT YK +G+++L +L    DW +TGHFPR+TLCDF+IR LG     T+QCVL +NLFNEK YIF+WF    V+I+++    +W L  + S+R       ++K +      +   L+ F++EHL+ DG F++ +I  NAGD V  +++  +W  Y+     K S    D++Y +
Sbjct:   30 INSYYTPIIIIFISTIIGTKMYLVGDPVQCWIPPEFKDGWEQFAENYCWVKNTYYVPENESIPSDKLDRSREELTYYQWVPFVLALQALLFYLPSAIWKLLNWQSGIHISDLVSTALNCL---------------------------EDDEQKRQEKVALLTRHIELTIVKQRTQKYGLIVRTKRLIFRILFCGYT--KTGNYLTMMYLGIKLLFIANVVGQFFLLNSFLGTDYKFYGWEVLNDLINNRDWHHTGHFPRVTLCDFDIRVLGNMHPRTLQCVLVVNLFNEKAYIFLWFLFVFVSIITIVDAIAWFLWTVLSKRR---YATIKKYITPADQQERRMLRDFLEEHLRADGAFVLRIISKNAGDPVVSDVVKQLWDSYRASPSAKNSRPIRDNDYAD 400
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A267DF38 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 291.967 bits (746), Expect = 9.606e-90
Identity = 164/403 (40.69%), Postives = 240/403 (59.55%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYL-NDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSK-GSFAKTVR---SLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMS---LDSNYPE 1538
            IN +YT I+++ ++  I TK YL  D + CW+P EF   W Q+AENYCW++NTYY+P +  +P     R+  +L+YYQWVP+VLALQ  LFY P A W+L+NWQSGI+I DL++ A+N                E+D  K               +++  +  H+EL+I  +   K G   +T R    +LFCG+   K G YL  +Y+  KLL+I NVVGQ FLLNSF+GT YK +G+++L +L    DW +TGHFPR+TLCDF+IR LG     T+QCVL +NLFNEK YIF+WF    V+I+++    +W L  + S+R       ++K +      +   L+ F++EHL+ DG F++ +I  NAGD V  +++  +W  Y+    TK S    D++Y +
Sbjct:   30 INSYYTPIIIIFISTIIGTKMYLVGDPVQCWIPPEFKDGWEQFAENYCWVKNTYYVPENESIPSDKLDRSREELTYYQWVPFVLALQALLFYLPSAIWKLLNWQSGIHISDLVSTALNCL--------------EDDKQKRQ-------------EKVALLTRHIELTIVKQRTQKYGLIVRTKRLIFRILFCGYT--KTGNYLTMMYLGIKLLFIANVVGQFFLLNSFLGTDYKFYGWEVLNDLINNRDWHHTGHFPRVTLCDFDIRVLGNMHPRTLQCVLVVNLFNEKAYIFLWFLFVFVSIITIVDAIAWFLWTLLSKR---RYATIKKYITPADQQERRMLRDFLEEHLRADGAFVLRIISKNAGDPVVSDVVKQLWDSYRASPSTKNSRPIRDNDYAD 400
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A1I8J2L7 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 290.041 bits (741), Expect = 4.307e-89
Identity = 163/403 (40.45%), Postives = 239/403 (59.31%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYL-NDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSK-GSFAKTVR---SLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMS---LDSNYPE 1538
            IN +YT I+++ ++  I TK YL  D + CW+P EF   W Q+AENYCW++NTYY+P +  +P     R+  +L+YYQWVP+VLALQ  LFY P A W+L+NWQSGI+I DL++ A+N                E+D  K               +++  +  H+EL+I  +   K G   +T R    +LFCG+   K G YL  +Y+  KLL+I NVVGQ FLLNSF+GT YK +G+++L +L    DW +TGHFPR+TLCDF+IR LG     T+QCVL +NLFNEK YIF+WF    V+I+++    +W L  + S+R       ++K +      +   L+ F++EHL+ DG F++ +I  NAGD V  +++  +W  Y+     K S    D++Y +
Sbjct:   30 INSYYTPIIIIFISTIIGTKMYLVGDPVQCWIPPEFKDGWEQFAENYCWVKNTYYVPENESIPSDKLDRSREELTYYQWVPFVLALQALLFYLPSAIWKLLNWQSGIHISDLVSTALNCL--------------EDDKQKRQ-------------EKVALLTRHIELTIVKQRTQKYGLIVRTKRLIFRILFCGYT--KTGNYLTMMYLGIKLLFIANVVGQFFLLNSFLGTDYKFYGWEVLNDLINNRDWHHTGHFPRVTLCDFDIRVLGNMHPRTLQCVLVVNLFNEKAYIFLWFLFVFVSIITIVDAIAWFLWTLLSKR---RYATIKKYITPADQQERRMLRDFLEEHLRADGAFVLRIISKNAGDPVVSDVVKQLWDSYRASPSAKNSRPIRDNDYAD 400
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000056430.1 (SMESG000056430.1)

HSP 1 Score: 823.157 bits (2125), Expect = 0.000e+0
Identity = 425/426 (99.77%), Postives = 426/426 (100.00%), Query Frame = 3 
Query:  276 MDGLFAFSKSFDILYXXXXXXXXXXXINHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLDSNYPEEAQFL 1553
            MDGLFAFSKSFDILYRRGRDDDFFDRINHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLD+NYPEEAQFL
Sbjct:    1 MDGLFAFSKSFDILYRRGRDDDFFDRINHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLDNNYPEEAQFL 426
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000056430.1 (SMESG000056430.1)

HSP 1 Score: 676.011 bits (1743), Expect = 0.000e+0
Identity = 344/403 (85.36%), Postives = 365/403 (90.57%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIP---HDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLDSNYPEEAQFL 1553
            ++H +T++ L+I ++ IS+ QY+   I CW+P EFS  W +YA NYCWI+NTY +P    D  +PK    R   +++YYQWVP VL  Q  LFYFP   WR++NW  GINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLD+NYPEEAQFL
Sbjct:   31 LSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKP-SERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLDNNYPEEAQFL 432
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000035987.1 (SMESG000035987.1)

HSP 1 Score: 284.648 bits (727), Expect = 1.045e-89
Identity = 149/388 (38.40%), Postives = 233/388 (60.05%), Query Frame = 3 
Query:  357 NHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYI-PHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLL---FCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIAS-QRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSE 1505
            NH++T+I+LV  ++ +ST+QY+   I CW+P EF+    +YAE+ CW+ +TY+I P+   +P++   R   ++ YYQWVP++L LQ  LF FP   WRL+NWQSG+NI  +I+ A +  T +  D ++ K N                        +  +  H++ +++ +   +       R  L   FC +  R+YG YL+ +Y   K LYI+NV+GQ FL+N F+GT+Y  +G  +++ L+ GN+W  +G+FPR+T+CDF IR L  +  YTVQCVLPINLFNEKI+IF+WFW   +AI++V+S   W  + +   QR+ FI+  L  +       D  +L  FID  L+ DGVF++ L+ LN GDL+  E+ + +W R+K+ + 
Sbjct:   30 NHFFTTILLVCFSLVVSTRQYVGKPIACWVPTEFTSSQEEYAESICWVSSTYFINPYQGSIPENTQQREEKKILYYQWVPFILMLQAILFNFPCCVWRLLNWQSGLNISAIIDIAGD--TEMIKDYEQRKAN------------------------LDFITRHIDDTLRIQREYRNGCTVQCRHCLAQHFCMWFGRRYGNYLVCVYTICKSLYILNVIGQFFLMNRFLGTNYTFYGLDLIYQLSIGNEWTESGNFPRVTMCDFNIRKLANQHRYTVQCVLPINLFNEKIFIFLWFWFVFIAIITVHSFIHWTSKSVCRIQRYNFIRKFLVLKDALQEAGDRKKLYAFIDLFLQQDGVFILRLLALNCGDLIAAEITEYLWCRFKECAR 391
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000046667.1 (SMESG000046667.1)

HSP 1 Score: 276.174 bits (705), Expect = 1.019e-86
Identity = 156/395 (39.49%), Postives = 232/395 (58.73%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYI-PHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLL---FCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRM-IASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYK-KLSETKMSL 1520
            +NH +TS +LVI  + IS +QY+   I CW+P EFS+   +YAE+ CW+ +TY++ P    +P++   R   +L YYQWVP++L  Q FLF  P   WRL NWQSGIN+  ++  A +V   I  D +  K N                        +  +A+H++  + +   ++ +    +R+ +    C + S+ YG YLI LYI  K+LYI+NV+ Q F++N  +GT+Y  +GF ++  LA G  W  +GHFPRIT+CDFEIR L  +  YTVQCVLPIN+FNEKI+IF+WFW  +V+ ++V S  S   ++ +   R  F+   L+ R K   T   N+ + F+++HL+ DGVFL+ L+  NAGDL+  E+ D +W  Y    SETK  L
Sbjct:   29 LNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDV--EIIKDRECRKVN------------------------VSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKP-ETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDL 396
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000046667.1 (SMESG000046667.1)

HSP 1 Score: 276.559 bits (706), Expect = 1.442e-86
Identity = 156/395 (39.49%), Postives = 232/395 (58.73%), Query Frame = 3 
Query:  354 INHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYI-PHDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLL---FCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRM-IASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYK-KLSETKMSL 1520
            +NH +TS +LVI  + IS +QY+   I CW+P EFS+   +YAE+ CW+ +TY++ P    +P++   R   +L YYQWVP++L  Q FLF  P   WRL NWQSGIN+  ++  A +V   I  D +  K N                        +  +A+H++  + +   ++ +    +R+ +    C + S+ YG YLI LYI  K+LYI+NV+ Q F++N  +GT+Y  +GF ++  LA G  W  +GHFPRIT+CDFEIR L  +  YTVQCVLPIN+FNEKI+IF+WFW  +V+ ++V S  S   ++ +   R  F+   L+ R K   T   N+ + F+++HL+ DGVFL+ L+  NAGDL+  E+ D +W  Y    SETK  L
Sbjct:   43 LNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDV--EIIKDRECRKVN------------------------VSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKP-ETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDL 410
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-94.344e-8738.66Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O0... [more]
inx-12.159e-8438.85Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-12.159e-8438.85Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-12.557e-8339.37Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-138.160e-8037.17Innexin [Source:UniProtKB/TrEMBL;Acc:O44887][more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Inx22.688e-1324.28gene:FBgn0027108 transcript:FBtr0301860[more]
Inx22.688e-1324.28gene:FBgn0027108 transcript:FBtr0071005[more]
Inx22.688e-1324.28gene:FBgn0027108 transcript:FBtr0332314[more]
Inx22.688e-1324.28gene:FBgn0027108 transcript:FBtr0071006[more]
shakB3.520e-927.34gene:FBgn0085387 transcript:FBtr0112570[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
panx1b8.739e-623.00pannexin 1b [Source:ZFIN;Acc:ZDB-GENE-070705-192][more]
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O01393|UNC9_CAEEL5.526e-8638.66Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q03412|UNC7_CAEEL7.304e-7235.90Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|A8WVX4|INX19_CAEBR1.686e-6432.84Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=i... [more]
sp|O61715|INX19_CAEEL1.145e-6233.33Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
sp|Q19746|INX3_CAEEL2.407e-6134.48Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
Q9NCL54.538e-14456.01Innexin OS=Girardia tigrina OX=6162 GN=Panx1 PE=2 ... [more]
A0A1I8IYE03.930e-9038.08Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A267DW924.785e-9040.45Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A267DF389.606e-9040.69Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A1I8J2L74.307e-8940.45Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000056430.10.000e+099.77SMESG000056430.1[more]
SMESG000056430.10.000e+085.36SMESG000056430.1[more]
SMESG000035987.11.045e-8938.40SMESG000035987.1[more]
SMESG000046667.11.019e-8639.49SMESG000046667.1[more]
SMESG000046667.11.442e-8639.49SMESG000046667.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024236 ID=SMED30024236|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1649bp
AGAATGTTAAACTGGACATTGGGTAATTAAATTAATTAAATTATTTATTA
AAAAAAAATCGATTATTAAAACTAGTGCGTGTTATTTTTTAATCGACATG
CGATCTAATTTATTATTTTGAACGTCAACTGTGATCTACATGAACATTGA
CAGTTGTGTATCATTTGAAAGTTGAGTTGAATGTCTCAGGGGTTTTATTG
AGATAAGAAAGTTCAAGGGTTAATTATATACTTGTGTAAATGTTATCATA
AAAAATAGTCAATTTTTTTTCAACTATGGATGGCTTGTTTGCATTTTCCA
AATCCTTCGATATTCTATATAGAAGAGGCAGAGATGATGATTTCTTCGAT
AGAATTAACCATTGGTATACGAGTATTGTTTTGGTGATCATGGCGATCTT
TATAAGCACAAAGCAATATCTGAATGATTCAATCACTTGCTGGATGCCTG
TTGAATTCAGTAAACCCTGGGTACAATATGCGGAGAATTATTGCTGGATA
CAGAACACGTATTACATTCCTCATGATACTGAATTACCAAAGAGTCATGG
ATATCGAACTACTTCTCAATTGTCATACTATCAATGGGTTCCATATGTTT
TAGCTTTACAAACATTTTTGTTTTACTTTCCCAGAGCTTTCTGGAGATTA
ATGAATTGGCAAAGCGGAATCAACATTCAAGATTTGATCAACAAGGCGAT
GAATGTTTGCACGACAATCAGACCAGACGTACAGAAACCAAAACCTAATG
ACGAAAATGATGCTAGTAAAGAAACTAAAGTACCGATACAAGAAGACATT
GAGCCAGAAGTCCCACAAGAAATCAAGGACATGGCTTATCACTTAGAGCT
TTCAATTCAGTCAGAATCTAATTCAAAAGGAAGCTTTGCCAAAACTGTTA
GGAGTTTATTATTTTGTGGGTTTGGCAGTCGTAAATATGGGTTTTATTTA
ATAACGCTTTATATCTTTACGAAACTGCTATATATTATTAATGTCGTAGG
TCAGTTATTTTTATTGAACAGTTTTATTGGAACCTCATACAAATTGTTTG
GATTTCAAATGCTTTTTAATCTAGCCAAAGGAAATGACTGGAAAAACACA
GGACATTTTCCTCGGATTACTTTGTGTGATTTTGAAATTAGGAATCTTGG
ACAACGAACTAACTACACGGTTCAATGCGTTTTACCAATCAACCTTTTCA
ATGAGAAGATTTATATTTTCATTTGGTTTTGGATTTTCATTGTTGCAATT
CTGTCTGTTTACAGTTTATTCAGCTGGCTATTACGAATGATTGCCAGTCA
GAGATTTAAATTCATTCAAGGTTTATTAGAAAAACGACTGAAAAACTGGT
CGACTACTGACAATAACCAACTGAAAAGATTTATAGATGAACACTTGAAA
ACCGACGGAGTATTTTTGATTTATCTGATCTATCTTAATGCCGGCGACCT
TGTGACCAAGGAATTGTTAGACGTTATGTGGTATCGGTACAAAAAGCTTT
CAGAAACAAAGATGTCACTTGATAGCAACTACCCAGAAGAGGCTCAATTT
TTATAAAAAAACACTGACATAATATTGTATTTTTTGACATTTTAATGTTA
ATTATATTTCATTCATAAACTATCAAATAAAACTGAAATTAAAAAAAAA
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protein sequence of SMED30024236-orf-1

>SMED30024236-orf-1 ID=SMED30024236-orf-1|Name=SMED30024236-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=427bp
MDGLFAFSKSFDILYRRGRDDDFFDRINHWYTSIVLVIMAIFISTKQYLN
DSITCWMPVEFSKPWVQYAENYCWIQNTYYIPHDTELPKSHGYRTTSQLS
YYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRP
DVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNS
KGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSF
IGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQ
CVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGL
LEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDV
MWYRYKKLSETKMSLDSNYPEEAQFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: cellular component
TermDefinition
GO:0005921gap junction
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000990InnexinPRINTSPR01262INNEXINcoord: 101..123
score: 55.48
coord: 301..317
score: 63.76
coord: 44..55
score: 38.33
coord: 277..286
score: 69.6
coord: 72..81
score: 58.0
coord: 229..243
score: 48.8
IPR000990InnexinPFAMPF00876Innexincoord: 21..405
e-value: 2.6E-111
score: 372.3
IPR000990InnexinPANTHERPTHR11893INNEXINcoord: 14..416
IPR000990InnexinPROSITEPS51013PANNEXINcoord: 16..411
score: 36.83
NoneNo IPR availableTMHMMTMhelixcoord: 27..49
NoneNo IPR availableTMHMMTMhelixcoord: 225..247
NoneNo IPR availableTMHMMTMhelixcoord: 314..336
NoneNo IPR availableTMHMMTMhelixcoord: 101..123