Guanylate cyclase

Query: 1248 ATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITP---VAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-----EQKLSNLLWKVDFKDVTITDVLPEYDNNKPR-NYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            A+FH  D  +++ +A+        +  +G  I + ++++SF+ VTG  + +D  GD E +F++          W++ P       + N N T  +     GR+++W  G+PP   PKCGF NE+     + L+    + ++ + +L  ++ + ++I      E++L++ LW+V ++DV  + +     +   R       ++Y  L+  E +            + F K   YKG +V++K +N K IELTRK   E++  +D+  E+L R +G C DPPNICILT YC RGSL+DIL N+ I LD +F  SL  D++KGM++LH+  I  HGNL++S C++D R++L+IT +GL+S R   P+              Y K LW +PE L+   P  RGSQ GD+YSF II  E+  ++G +       +  EII ++   T  E    RP +        +   +  CW +  + RP F+ IR+ L+   +   SNI DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFT+LSA STPM+VV +LNDLYT FD++I  +DVYKVETIGDAYMVVSGLP+RN  LHA E+A ++L LL A++SF IRHRP E L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEALKIH SSETK +L+  GG+ L  RG++E+KGKG + TY+L  E
Sbjct:  351 ASFH--DGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGY-LKIDSSGDRETDFSL----------WDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQF-----------QVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQ---------GHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERV---TRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGE 1054          

Query: 1239 LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLE------LNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLK-EPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPG---NATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            L A  F  +D  +++ + ++   Q   +  +G +I++++  + +  VTGL V MDK+ D E +F + +  ++++G  +  P A++     +   K   + GR I W+ G PP   P C F  ++   +      L I+AL   +  I+ G    L+  R  + E++L+++LW++ ++++           N  R ++   +  +  L    + S        +I   F   G +KG +V+IK +N K IELTR+   E++  +D+   +L R IG C+DPPNICI+T YC RGSL+DIL N  I LD +F  SL+ DL+KGM +LH+S I+ HG+L++S C++DSR++L+IT +GL S R  +  D        D+   Y K LW +PE L   P P + G QK D+YSF II  E+  ++GP+   Y  G   +  EI++K++N    +    RP ID TQ+   +   +  CW      RPDF  I+  ++   K   ++I DN+LL ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFT+LSA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP RN   HA EIA ++L LL A+ SF IRHRP++ L+LRIG+H+GP  AGVVGLKMPRYCLFGDTVNTASRME+ G+ALKIH SS TK  LD LG + L  RG++E+KGKG M TY+L  E
Sbjct:  332 LIAGCF--YDGILLYAEVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGL-VVMDKNNDRETDFVLWAMGDLDSG--DFQPAAHY-----SGAEKQIWWTGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLI-FRKLMLEKELASMLWRIRWEELQF--------GNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQI---FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPD--------DSHALYAKKLWTAPELLSGNPLPTT-GMQKADVYSFGIILQEIALRSGPF---YLEGLDLSPKEIVQKVRN---GQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGE 1039          

Query: 1533 FPGRQISWISGHPPFHEPKCGFSNEN-CRLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWK------VDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPR----SSCKIRKTF--TKIGSYKGMIVSIK------FLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALG-GYCLIKRGNIEVKGKGDMITYFL 3431
            F G  I +  G PP  + KC F+    C   ++  A ++ VC+ +  AL  +    Y+I  +     L K      +  +DVT  +  P + +      R      SF +  E +S R PR    S      T+  + I  Y+G  V +K      F + KSI+   +     +  KD+  EN+N ++G   D     I+T +CSRGSL+DIL+N+D+ LD +F +SLL DLIKGM YLH  +   HG L++  C++D R++L++T +G   I               + E    +LLW +PE L+ P     GS  GD+YSFAII  E+  +  P+  +  P  A EII +LK         +         P      + +CW + +E+RP F  I    K   KG ++NI D+ML ++E+Y+ NLE L+ ERT +L  EK+K E+LL +MLP SV E LK G TV PE +  VT+YFSDIVGFT++SA S P+EVV +LNDLYTLFD+II  +DVYKVETIGDAYMV SGLP RN   HA EIA++SL +L ++ +F +RH P   +++RIG+HSGP VAGVVGL MPRYCLFGDTVNTASRME+TG   +IH S  T  +L  L  GY +  RG  E+KGKG   T++L
Sbjct:  433 FGGTPIHFPGGRPPRADAKCWFAEGKICHGGIDP-AFAMMVCLTLLIALLSINGFAYFIRRRINKIQLIKGPNRILLTLEDVTFIN--PHFGSK-----RGSRASVSFQITSEVQSGRSPRLSFSSGSLTPATYENSNIAIYEGDWVWLKKFSLGDFGDLKSIK--SRASDVFEMMKDLRHENINPLLGFFYDSGMFAIVTEFCSRGSLEDILTNQDVKLDWMFKSSLLLDLIKGMKYLHHREF-VHGRLKSRNCVVDGRFVLKVTDYGFNDIL--------EMLRLSEEESSMEELLWTAPELLRAPRGSRLGSFAGDVYSFAIIMQEVMVRGTPFCMMDLP--AQEIINRLKKPPPVYRPVVP----PEHAPPECLQLMKQCWAEAAEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQNLSEGYEVELRGRTELKGKGTEETFWL 1060          

Query: 1560 SGHPPFHEPKCGFSNENC---RLE--LNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTK------IGSYKGMIVSIK-FLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCL----DPP------NICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDAL-GGYCLIKRGNIEVKGKGDMITYFL 3431
             G  P  +P C F   N     LE  L  L   + V + +AGA FL   +R+ +   ++ +   K+     T+ D+           + +     S  VA    S    RS   IR   ++      IG Y+G  V +K F   + I +    +      +++  EN+   +G+ L    + P      N+ +++ +C+RGSL+D+L+ ++I LD +F +SLL DLIKG+ YLH   +  HG L++  C++D R++L+IT  G   +  A    P   P + D        LW +PE L++P    RG+  GD++S AII  E+  ++ P+  +       E+++++++         RP++   Q P      + +CW +  E RP       + K + KG ++NI D+ML ++E+Y+ NLE L+ ERT +L  EK+K +RLL +MLP SV E LK G  V PE++  VT+YFSDIVGFT++SA S P+EVV +LNDLYTLFD+II  +DVYKVETIGDAYMV SGLP RN   HA EIA++SL +L A+ +F +RH P   +++RIG+HSGPCVAGVVGL MPRYCLFGDTVNTASRME+TG   +IH +  T  +L AL  GY +  RG  E+KGKG   T++L
Sbjct:  439 GGSAPGPDPSCWFDPNNICGGGLEPGLVFLGFLLVVGMGLAGA-FLAHYVRHRLLHMQMVSGPNKIIL---TVDDI----------TFLHPHGGTSRKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDLLAQREIKLDWMFKSSLLLDLIKGIRYLHHRGVA-HGRLKSRNCIVDGRFVLKITDHGHGRLLEAQKVLPEP-PRAEDQ-------LWTAPELLRDPALERRGTLAGDVFSLAIIMQEVVCRSAPYAMLEL--TPEEVVQRVRSPPP----LCRPLVSMDQAPVECILLMKQCWAEQPELRPSMDHTFDLFKNINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELELEKQKTDRLLTQMLPPSVAEALKTGTPVEPEYFEQVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGTFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNLSTVGILRALDSGYQVELRGRTELKGKGAEDTFWL 1056          

Query: 1812 NIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGS--YKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSN-----KDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPII-------DETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGL-----RSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIK-RGNIEVKGKGDMITYFL 3431
            N  NH S  + D+           K R T  ++    Y    V +K L H     T K + E+     ++  NL +  G       I  +  YC RGSL+++L++        F+D  F  S+L+D+ KGM YLH S+   HG L+++ C++DSR +++IT FG  SI    PK                K LW +PEHL++    +  SQKGD+YS+ II  E+  +   + ++       +I R    E SN +   RP +        E +V   VK+C    W++  E+RPDFK I   L  +  GL       +  D ++  ++ Y++NLE LVEERT     E+ + +RL   +LP+ V + LK    V PE Y  VTIYFSDIVGFT++   STPMEVV MLND+Y  FD I+  +DVYKVETIGDAYMV SGLP RN + HA +IA ++L +L  + +F + H P   + +RIG+HSGPC AGVVG+KMPRYCLFGDTVNTASRME+TG  L+IH S  T  +L       L + RG   +KG+G+  TY+L
Sbjct:  482 NETNHVSLKIDDD-----------KRRDTIQRLRQCKYDKKRVILKDLKHNDGNFTEKQKIELNKLLQIDYYNLTKFYGTVKLDTMIFGVIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSSKTEVHGRLKSTNCVVDSRMVVKITDFGCNSI--LPPK----------------KDLWTAPEHLRQ----ANISQKGDVYSYGIIAQEIILRKETFYTLSCRDRNEKIFRV---ENSNGMKPFRPDLFLETAEEKELEVYLLVKNC----WEEDPEKRPDFKKIETTLAKIF-GLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADRLNFMLLPRLVVKSLKEKGFVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDHIVDHHDVYKVETIGDAYMVASGLPKRNGNRHAIDIAKMALEILSFMGTFELEHLPGLPIWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHVSGSTIAILKRTECQFLYEVRGETYLKGRGNETTYWL 1000          

Query:  543 CDYEAALSGALNVAFFATECSNVELS-DKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQW----------KLASDELKQVAHXXXXXXXXXXXXXXDNAS-----KSMKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKF--VNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTAT----PNPIILEA---------LGLAICHEGFNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRN------DSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTE----METGQWNITPV-------AYFIQNLN-NTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-------EQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVAD--EFESRRKPR-SSCKIRKTFTK-IGSYKGMIVSIKFL--NHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHL---------KEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIY----------RPGNATEIIRKLKNETSNELSS---MRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGL-RSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPM-RNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALG-GYCLIKRGNIEVKGKGDMITYFL 3431
            C  EAA++ + N+   +  C++ ++S D   + TFART PP  +  K+ ++LM +++W KF++V    +            ++   E K   HK +I+   +   ++ + S     +S++  I ST +  RIY+   +V      +++M  + +    +Y++I+V   +  +N +     +  R     L+ + +   ++ R ML  + +     P P+ L +          G  + H G     NLK                    + +D   ++ KAI  + +        D   +G  I+  I ++ ++S+ G ++ +D+ G+++GNF++ S+ +    M     +  P+       A F++  + + LP    F   +I W+ G PP  EP CGF  ENCR +     L+V V +++A  +F LV   + +N       E++LS ++WK+D            Y+  +     N ++  S + +D  +F   + P  S   ++ T  + + SYKG +V +K L    K  +LTR+ ++E++  + +   N+N  +G+ +   ++ ++  YCS+GSL DIL N+++ LD ++VAS + DL+KGM+Y+HDS++  HGNL+++ CLI SRW LQI  FGL+ +R     D S           +   LW +PE +           P P      K D YSF IIFHE+  + GP+  IY           P   +   R L  +T   + S    RP   + +V N+VK+ +  CW     +RP+FK I+  LKPL   + + NI D+M+L+MEKY   LE LV+ERT +L +E+++ + LL RMLP SV EQL  GQ VIPE +  VTIYFSDIVGFT++S  STPMEVV  LN LYTLFDSII  YDVYKVETIGDAYMVVSG+P  +  + HA +IA +++H+L A++SF I HR  E L +RIG+H+GPCVAGVVG  MPRY LFGDTVNTASRME+ GEAL+IH SS T+ +L ++  G+ L +RG++ +KGKG M TY+L
Sbjct:  200 CKTEAAMAASQNLPIISYRCNDQDISRDDYHYRTFARTVPPAGEIFKAFMSLMKQYNWRKFSVVYDVKKGQVKNELFETLKRMVETENKFEEHKFEIMNVSKLEFSKMDISSQQDIQSIENAIKSTMQTTRIYLTFDNVRLFRTMLSIMGEMGLTQQ-DYMLIYVDTNYDWLNVYHSMNNHFLRNTMTYLHHSWDANNSSDRKMLDYARSALSIIPTPVKLNSQRFYNFWKKAGDYMHHFGVQKADNLKG--------------NRIACYLYDAVYLYAKAIHELVEEYGNDDSYDPTADGKAIIDRIVNKKYRSIQGFDMRIDERGNSKGNFSLLSWQKVAPIMNKSDPSYYPLDHALDLTAIFVEAPDKDRLPNL-QFKSSRIQWLKGEPPPDEPVCGFHGENCRKKGIFSYLTVVVMILIA--VFSLVLTGFTLNYIRSRRFEKELS-MIWKID-----------PYEVRRVVGGVNNESTASLMQSDVMQFAKTKTPWWSKAPVQGTGMRGLASYKGTLVGLKDLMYGRKPKDLTREAKKELRAMRQLAHPNVNNFLGIIVCQYSVTVVREYCSKGSLHDILRNENLKLDHMYVASFVDDLVKGMVYIHDSELKMHGNLKSTNCLITSRWTLQIADFGLRELREGIMYDSS--------YNIWENFLWTAPEAMTINGSLAISNPPTP------KADAYSFGIIFHEIFTREGPY-KIYVQRGDVNGEAAPKKDSVECRALVEKTVRRVYSDPYFRPDTSDLEVQNYVKEVMAACWHHDPYQRPEFKTIKNKLKPLFHQIYKQNIMDHMVLMMEKYQTQLEDLVDERTIELKDEQRRSQHLLQRMLPSSVAEQLLAGQDVIPEAFPPVTIYFSDIVGFTTISGESTPMEVVTFLNKLYTLFDSIIRRYDVYKVETIGDAYMVVSGVPQYKTMEYHAEQIAMMAIHILSAVRSFSIPHRSCEPLMIRIGMHTGPCVAGVVGKTMPRYTLFGDTVNTASRMESNGEALRIHCSSSTQKVLTSIDQGFLLEERGSLAIKGKGQMTTYWL 1204          

Query: 1893 KTFTKIGSYKGMIVSIKFLN-----HKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDET---QVPNFVKDCL----TECWDDVSERRPDFKFIRVILKPLLK-GLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFL 3431
            + +TK   +KG++V+IK LN     +  ++L+R    E++  KD+  +++ R  G C+D P+ C++T YC +GSL+DIL N+ I LD++   SLL DL+KG+ +LH+S+I  HG L++S C++DSR++L++T FGL  +      +       +    YY K+LW +PE L++      G+QKGDIYSFAII HE+  + G +       +  EI+++++   S +   +RP + ET   +  + + D L      CW +    RP+   +R  ++ L +    SN+ DN+L  ME+YA NLE LVEERT +   EKKK+E LL ++LP ++ + L  G+ V  E Y CVTIYFSDIVGFTSLS+ STPM+VV +LNDLY  FD ++  + VYKVETIGDAYMVVSGLP R  D HA +IA +SL LL  +K+FVIRHRP+E LKLRIG+HSG  VAGVVG KMPRYCLFGDTVNT+SRME+ G  LKIH S +T  +L    G+ L  RG++E+KGKG   TY+L
Sbjct:  681 QIYTKTAIFKGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQHDHITRFTGACIDFPHYCVVTEYCPKGSLEDILENEKIELDKLMKYSLLHDLVKGLFFLHNSEIRSHGRLKSSNCVVDSRFVLKVTDFGLHRLHCLEEINL----EEIGEHAYYKKMLWTAPELLRDSNAPPMGTQKGDIYSFAIILHEMMFRKGVFALENEDLSPNEIVQRVRKPVSEDQEPLRPWVSETGEGEGDDALNDTLLSLMVACWSEDPHERPEVSSVRKAVRSLNRDNETSNLVDNLLKRMEQYANNLEGLVEERTQEYLAEKKKVEELLHQLLPPAIADTLIAGRAVQAESYDCVTIYFSDIVGFTSLSSQSTPMQVVTLLNDLYLAFDGVVDNFKVYKVETIGDAYMVVSGLPERRDD-HANQIAQMSLSLLHKVKNFVIRHRPHEQLKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGLPLKIHVSQQTYDILMQEAGFKLELRGSVEMKGKGMQTTYWL 1201          

Query: 1263 FDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENC----RLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDV 1757
            +D  +++  A++   Q      NG  I   ++ ++F  +TG NV +D +GD   ++   S  +++  Q     VAY+    +N L         Q+ W+ G PP   P CG+    C     L + +L  S  + +++ G LF+    RY + EQ+L+ + WK+ ++++
Sbjct:  356 YDAVLLYAIALNETIQSGLDPRNGHNITSRMWGRTFVGITG-NVSIDHNGDRYSDY---SLLDLDPVQNRFVEVAYY-SGASNQLKTVG-----QLHWVGGKPPTDLPICGYDKSKCPQGYPLHVYLLMGSFLLILVLVG-LFIFFWRRYKL-EQELAAMSWKIRWEEL 512          

Query: 1893 KTFTKIGSYKGMIVSIKFLN-----HKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDET---QVPNFVKDCL----TECWDDVSERRPDFKFIRVILKPLLK-GLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFL 3431
            + +TK   +KG++V+IK LN     +  ++L+R    E++  KD+  +++ R  G C+D P+ C++T YC +GSL+DIL N+ I LD++   SLL DL+KG+ +LH+S+I  HG L++S C++DSR++L++T FGL  +      +       +    YY K+LW +PE L++      G+QKGDIYSFAII HE+  + G +       +  EI+++++   S +   +RP + ET   +  + + D L      CW +    RP+   +R  ++ L +    SN+ DN+L  ME+YA NLE LVEERT +   EKKK+E LL ++LP ++ + L  G+ V  E Y CVTIYFSDIVGFTSLS+ STPM+VV +LNDLY  FD ++  + VYKVETIGDAYMVVSGLP R  D HA +IA +SL LL  +K+FVIRHRP+E LKLRIG+HSG  VAGVVG KMPRYCLFGDTVNT+SRME+ G  LKIH S +T  +L    G+ L  RG++E+KGKG   TY+L
Sbjct:  702 QIYTKTAIFKGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQHDHITRFTGACIDFPHYCVVTEYCPKGSLEDILENEKIELDKLMKYSLLHDLVKGLFFLHNSEIRSHGRLKSSNCVVDSRFVLKVTDFGLHRLHCLEEINL----EEIGEHAYYKKMLWTAPELLRDSNAPPMGTQKGDIYSFAIILHEMMFRKGVFALENEDLSPNEIVQRVRKPVSEDQEPLRPWVSETGEGEGDDALNDTLLSLMVACWSEDPHERPEVSSVRKAVRSLNRDNETSNLVDNLLKRMEQYANNLEGLVEERTQEYLAEKKKVEELLHQLLPPAIADTLIAGRAVQAESYDCVTIYFSDIVGFTSLSSQSTPMQVVTLLNDLYLAFDGVVDNFKVYKVETIGDAYMVVSGLPERRDD-HANQIAQMSLSLLHKVKNFVIRHRPHEQLKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGLPLKIHVSQQTYDILMQEAGFKLELRGSVEMKGKGMQTTYWL 1222          

Query: 1263 FDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENC----RLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDV 1757
            +D  +++  A++   Q      NG  I   ++ ++F  +TG NV +D +GD   ++   S  +++  Q     VAY+    +N L         Q+ W+ G PP   P CG+    C     L + +L  S  + +++ G LF+    RY + EQ+L+ + WK+ ++++
Sbjct:  377 YDAVLLYAIALNETIQSGLDPRNGHNITSRMWGRTFVGITG-NVSIDHNGDRYSDY---SLLDLDPVQNRFVEVAYY-SGASNQLKTVG-----QLHWVGGKPPTDLPICGYDKSKCPQGYPLHVYLLMGSFLLILVLVG-LFIFFWRRYKL-EQELAAMSWKIRWEEL 533          

Query: 1893 KTFTKIGSYKGMIVSIKFLN-----HKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDET---QVPNFVKDCL----TECWDDVSERRPDFKFIRVILKPLLK-GLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFL 3431
            + +TK   +KG++V+IK LN     +  ++L+R    E++  KD+  +++ R  G C+D P+ C++T YC +GSL+DIL N+ I LD++   SLL DL+KG+ +LH+S+I  HG L++S C++DSR++L++T FGL  +      +       +    YY K+LW +PE L++      G+QKGDIYSFAII HE+  + G +       +  EI+++++   S +   +RP + ET   +  + + D L      CW +    RP+   +R  ++ L +    SN+ DN+L  ME+YA NLE LVEERT +   EKKK+E LL ++LP ++ + L  G+ V  E Y CVTIYFSDIVGFTSLS+ STPM+VV +LNDLY  FD ++  + VYKVETIGDAYMVVSGLP R  D HA +IA +SL LL  +K+FVIRHRP+E LKLRIG+HSG  VAGVVG KMPRYCLFGDTVNT+SRME+ G  LKIH S +T  +L    G+ L  RG++E+KGKG   TY+L
Sbjct:  740 QIYTKTAIFKGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQHDHITRFTGACIDFPHYCVVTEYCPKGSLEDILENEKIELDKLMKYSLLHDLVKGLFFLHNSEIRSHGRLKSSNCVVDSRFVLKVTDFGLHRLHCLEEINL----EEIGEHAYYKKMLWTAPELLRDSNAPPMGTQKGDIYSFAIILHEMMFRKGVFALENEDLSPNEIVQRVRKPVSEDQEPLRPWVSETGEGEGDDALNDTLLSLMVACWSEDPHERPEVSSVRKAVRSLNRDNETSNLVDNLLKRMEQYANNLEGLVEERTQEYLAEKKKVEELLHQLLPPAIADTLIAGRAVQAESYDCVTIYFSDIVGFTSLSSQSTPMQVVTLLNDLYLAFDGVVDNFKVYKVETIGDAYMVVSGLPERRDD-HANQIAQMSLSLLHKVKNFVIRHRPHEQLKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGLPLKIHVSQQTYDILMQEAGFKLELRGSVEMKGKGMQTTYWL 1260          

Query: 1263 FDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENC---RLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDV 1757
            +D  +++  A++   Q      NG  I   ++ ++F  +TG NV +D +GD   ++   S  +++  Q     VAY+    +N L         Q+ W+ G PP   P CG+    C    L + +L  S  + +++ G LF+    RY + EQ+L+ + WK+ ++++
Sbjct:  403 YDAVLLYAIALNETIQSGLDPRNGHNITSRMWGRTFVGITG-NVSIDHNGDRYSDY---SLLDLDPVQNRFVEVAYY-SGASNQLKTVG-----QLHWVGGKPPTDLPICGYDKSKCPGYPLHVYLLMGSFLLILVLVG-LFIFFWRRYKL-EQELAAMSWKIRWEEL 558          

Query: 1263 FDLTMMFFKAIDNIFQRNDSELN-GTKILK-EIF-----DQSFKSVTGLNVYMDKHGDAEGNFTV-SSYTEMETGQWNITPVAYFIQN-LNNTLPKFTMFP-GRQISWISGHPPFHEPKCGFSNENCRLELN---ILALSVCVCVIVA---GALFLLVAIRY--------------WINEQKLSNLLWKVDFKDV------------TITD---VLPEYDNNKPRNYRNIDNHYSFLVADEF---ESRRKPRSSCKIRKTFT----KIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGS----QKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRP---IIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNV 3452
            +D   + F +I  +    +  LN G  I + +IF      +   SVTG+  ++D +G   G+  +   ++      +++ P A   Q+ L NT+   T +  G  I +++   P   P CGF  ENC    N   I+ +SV V V++     A FL    RY               I  +K +NL+ +   + +            T+ D    + +Y+N    N  +I N  S   A  F           + +  K        +G Y+G  V++K +    +E TR  R E+   ++    N+   +G+ +  P++ ++     RGSLKDIL N D+ LD++F + +  D+I G+ YLH S I  HG L+++ CLID+RW+++++ FGL+ +R         W    D ++   +L W SPE L+    +S+      QK D+YS AI+ +EL  + GPWG    P    EI+  +K E        RP   ++ E+  P  V++ +   W +    RP    I+  LKPL  GL+  I DNM+ ++EKY   LE  + ER  +L  EK K E LL  MLP+ V + LK+G  V  E +   T++FSD  GF  +SA+S P+++VQ LNDLYT+FD II ++DVYKVETI DAYMV SGLP+ N + HAGEIASL L LLKA++SF IRH PNE ++LRIG++SGPCVAGVVGLKMPRYCLFGDTVNTASRME+ G  L+I+ S   K +LD LGGY + +RG +E+KGKG  +TYF+  E+ ++
Sbjct:  244 WDRIKLLFDSIQYLADATNDALNIGANIYQSDIFYEYLISRKIDSVTGVTEFIDGYGAIVGSIQIYYHFSSSSHNSYSLFPCARLAQSSLLNTVWSLTDYSEGLSIDFVNKSAPKDTPVCGFYGENCGPPANNTFIIVISVGVAVLIGLAIAAAFLYKRYRYERRLHSLFFMIDRNQIILKKHTNLMSQQSLRSMASIHGSVVAASQTLRDSHFFIEDYNNASSINASSIFNTGSTARAGPFGPIPGFGGVTGASEDEKWHQIPDFGVGLYEGRTVALKRIYRSDVEFTRSIRLEIAKLQESVNSNVIEFVGMVVQSPDVFVVYELAQRGSLKDILDNDDMPLDDVFRSQMTKDIIAGLEYLHSSPIGCHGRLKSTNCLIDARWMVRLSSFGLRELR-----GEETWQQEDDVQEGKDQL-WTSPELLRWSTGLSQCGVLLVQKSDVYSLAIVLYELFGRLGPWGD--EPMEPREIVSLVKREALAGKKPFRPDMAVLKES--PRIVQETVVAAWTEDPLNRPSLHQIKRKLKPLTIGLKRTIMDNMVSMIEKYTDKLEKDIAERNEELEGEKAKSEALLKMMLPEVVADSLKLGSNVSAESFENCTVFFSDCPGFVEMSATSKPIDIVQFLNDLYTVFDRIIDQFDVYKVETIADAYMVASGLPVPNGNHHAGEIASLGLALLKAVESFKIRHLPNEKVRLRIGMNSGPCVAGVVGLKMPRYCLFGDTVNTASRMESNGIPLRINCSGTAKEILDQLGGYEIEERGIVEMKGKGKQMTYFVRGENSDM 1022          

Query:  453 KVTKYTSLPTIMRWVNENKLDGIFQLM--DDACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQW----KLASDELKQVAHXXXXXXXXXXXXXXDNASKS-MKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNF---------PTAAMRSMLFLSTATP-NPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSI-LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTV--------SSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPG-RQISWISGHPPFHEPKCGFSNENC-RLELN---ILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQ--VPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFL 3431
            K++ Y   P  +R + + +  G+   +  D++C  EA L+ A N    + +CS+  +S+K  F TFART  P SK  KS+I+L++ F W KF++V SS   W      A  EL +  +      K+         + S + +II+ T    RIYV +   + ++DF+  + + ++  SG+Y+++ V D      E+Y  N +RVN    N  D +            + RS++ +S   P NP I +     IC +          F  P    +  +I +     H +D  M++ +AI  + +      +G  ++  IF++S+ S+ G +VY+D +GDAEGN+TV        S  +     + ++ PV +F  + N+ +P+F      R I W++G PP  EP CGF  E C R +L+   +++  +C  V+V     L+   RY   EQ L+ LLWKVD KDVT+ + L EY+N   +N   I    S LV  E   R           +FT I  ++G IV++K ++ KS+++TR  R+E++  +++  EN+   IG   D  ++ I T YC+RGSL+D+L+N+D+ LD +F++SL+ D++KGMIYLHDS+I  HGNLR+S CLIDSRW+ QI+ FGL  ++ A  ++P+       +E    + L  +PE L++ Y   RGSQKGD+YSF I+ +E+  + GPWG      +  EII+ +K     +    RP +  T   +P++++ CL +CWD+  E RPD + +R+ LK L  GL+ NIFDNML IMEKYA NLE LV+ERT  L EEKKK + LL +MLP+ V E LK G  V  E + CVTI FSDIVGFT L  +STP EVV+MLND YT  DSII  YDVYKVETIGDAYMVVSGLP++N   HAGEIASL+LHLL+ + +  IRH+P ET++LRIG+HSGPC AGVVG KMPRYCLFGDTVNTASRME+TG++++IH S  T  LL  +G Y  I+RG   +KGKGDM TY+L
Sbjct:   91 KMSAYRVKP--LRAMTQMREAGVTAFIGPDESCTTEALLASAWNTPMLSFKCSDPIVSNKSTFHTFARTLAPASKVSKSVISLLNAFHWNKFSIVVSSKPIWGSDVARAIQELAEARNFTISHFKYISDYIPTTKTLSQIDKIIEETYATTRIYVFIGEHIAMVDFVRGLQNRRLLESGDYIVVSVDD------EIYDSN-RRVNIMERNYLDPYIRKEKSKSLDKISFRSVIKISMTYPQNPHIRD-----ICSK-IKDYARKTPFLVPYHQRVFDNISVPIYGLHLYDSVMIYVRAITEVLRLGGDIYDGNLVMSHIFNRSYHSIQGFDVYIDSNGDAEGNYTVITLQNDVGSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKNDRPIQWLNGRPPLAEPLCGFHGELCPRKKLDWRYLVSGPLCALVVVVAIALLIKHYRY---EQTLAGLLWKVDMKDVTVIN-LGEYNNPTNKNIFQICRQ-SILVVGEPNKR-----------SFTNIALFRGNIVAMKKIHKKSVDITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLANEDLHLDHMFISSLVSDILKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELK-AGQEEPNK------SELELKRALCMAPELLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAY--SKEEIIQFVKCPEMLQHGVFRPALTHTHLDIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNIFDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWL 1076          

Query:  453 KVTKYTSLPTIMRWVNENKLDGIFQLM--DDACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQW----KLASDELKQVAHXXXXXXXXXXXXXXDNASKS-MKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTV--------SSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPG-RQISWISGHPPFHEPKCGFSNENC-RLELN---ILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQ--VPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFL 3431
            K++ Y   P  +R + + +  G+   +  D++C  EA L+ A N    + +CS+  +S+K  F TFART  P SK  KS+I+L++ F W KF++V SS   W      A  EL +  +      K+         + S + +II+ T    RIYV +   + ++DF+  + + ++  SG+Y+++ V D      E+Y  N +RVN    N  D                   P I +    ++    F  +  +   T PQ   +   I      H +D  M++ +AI  + +      +G  ++  IF++S+ S+ G +VY+D +GDAEGN+TV        S  +     + ++ PV +F  + N+ +P+F      R I W++G PP  EP CGF  E C R +L+   +++  +C  V+V     L+   RY   EQ L+ LLWKVD KDVT+ + L EY+N   +N   I    S LV  E   R           +FT I  ++G IV++K ++ KS+++TR  R+E++  +++  EN+   IG   D  ++ I T YC+RGSL+D+L+N+D+ LD +F++SL+ D++KGMIYLHDS+I  HGNLR+S CLIDSRW+ QI+ FGL  ++ A  ++P+       +E    + L  +PE L++ Y   RGSQKGD+YSF I+ +E+  + GPWG      +  EII+ +K     +    RP +  T   +P++++ CL +CWD+  E RPD + +R+ LK L  GL+ NIFDNML IMEKYA NLE LV+ERT  L EEKKK + LL +MLP+ V E LK G  V  E + CVTI FSDIVGFT L  +STP EVV+MLND YT  DSII  YDVYKVETIGDAYMVVSGLP++N   HAGEIASL+LHLL+ + +  IRH+P ET++LRIG+HSGPC AGVVG KMPRYCLFGDTVNTASRME+TG++++IH S  T  LL  +G Y  I+RG   +KGKGDM TY+L
Sbjct:   91 KMSAYRVKP--LRAMTQMREAGVTAFIGPDESCTTEALLASAWNTPMLSFKCSDPIVSNKSTFHTFARTLAPASKVSKSVISLLNAFHWNKFSIVVSSKPIWGSDVARAIQELAEARNFTISHFKYISDYIPTTKTLSQIDKIIEETYATTRIYVFIGEHIAMVDFVRGLQNRRLLESGDYIVVSVDD------EIYDSN-RRVNIMERNYLD-------------------PYIRKEKSKSLDKISFRSVIKIS-MTYPQNPHIRVPIYG---LHLYDSVMIYVRAITEVLRLGGDIYDGNLVMSHIFNRSYHSIQGFDVYIDSNGDAEGNYTVITLQNDVGSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKNDRPIQWLNGRPPLAEPLCGFHGELCPRKKLDWRYLVSGPLCALVVVVAIALLIKHYRY---EQTLAGLLWKVDMKDVTVIN-LGEYNNPTNKNIFQICRQ-SILVVGEPNKR-----------SFTNIALFRGNIVAMKKIHKKSVDITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLANEDLHLDHMFISSLVSDILKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELK-AGQEEPNK------SELELKRALCMAPELLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAY--SKEEIIQFVKCPEMLQHGVFRPALTHTHLDIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNIFDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWL 1048          

Query:  453 KVTKYTSLPTIMRWVNENKLDGIFQLM--DDACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQW----KLASDELKQVAHXXXXXXXXXXXXXXDNASKS-MKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSI-LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTV--------SSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPG-RQISWISGHPPFHEPKCGFSNENC-RLELN---ILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQ--VPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFL 3431
            K++ Y   P  +R + + +  G+   +  D++C  EA L+ A N    + +CS+  +S+K  F TFART  P SK  KS+I+L++ F W KF++V SS   W      A  EL +  +      K+         + S + +II+ T    RIYV +   + ++DF+  + + ++  SG+Y+++ V D      E+Y  N +RVN                             I+E +   IC +          F  P    +  +I +     H +D  M++ +AI  + +      +G  ++  IF++S+ S+ G +VY+D +GDAEGN+TV        S  +     + ++ PV +F  + N+ +P+F      R I W++G PP  EP CGF  E C R +L+   +++  +C  V+V     L+   RY   EQ L+ LLWKVD KDVT+ + L EY+N   +N   I    S LV  E   R           +FT I  ++G IV++K ++ KS+++TR  R+E++  +++  EN+   IG   D  ++ I T YC+RGSL+D+L+N+D+ LD +F++SL+ D++KGMIYLHDS+I  HGNLR+S CLIDSRW+ QI+ FGL  ++ A  ++P+       +E    + L  +PE L++ Y   RGSQKGD+YSF I+ +E+  + GPWG      +  EII+ +K     +    RP +  T   +P++++ CL +CWD+  E RPD + +R+ LK L  GL+ NIFDNML IMEKYA NLE LV+ERT  L EEKKK + LL +MLP+ V E LK G  V  E + CVTI FSDIVGFT L  +STP EVV+MLND YT  DSII  YDVYKVETIGDAYMVVSGLP++N   HAGEIASL+LHLL+ + +  IRH+P ET++LRIG+HSGPC AGVVG KMPRYCLFGDTVNTASRME+TG++++IH S  T  LL  +G Y  I+RG   +KGKGDM TY+L
Sbjct:   91 KMSAYRVKP--LRAMTQMREAGVTAFIGPDESCTTEALLASAWNTPMLSFKCSDPIVSNKSTFHTFARTLAPASKVSKSVISLLNAFHWNKFSIVVSSKPIWGSDVARAIQELAEARNFTISHFKYISDYIPTTKTLSQIDKIIEETYATTRIYVFIGEHIAMVDFVRGLQNRRLLESGDYIVVSVDD------EIYDSN-RRVN-----------------------------IMERID--ICSK-IKDYARKTPFLVPYHQRVFDNISVPIYGLHLYDSVMIYVRAITEVLRLGGDIYDGNLVMSHIFNRSYHSIQGFDVYIDSNGDAEGNYTVITLQNDVGSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKNDRPIQWLNGRPPLAEPLCGFHGELCPRKKLDWRYLVSGPLCALVVVVAIALLIKHYRY---EQTLAGLLWKVDMKDVTVIN-LGEYNNPTNKNIFQICRQ-SILVVGEPNKR-----------SFTNIALFRGNIVAMKKIHKKSVDITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLANEDLHLDHMFISSLVSDILKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELK-AGQEEPNK------SELELKRALCMAPELLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAY--SKEEIIQFVKCPEMLQHGVFRPALTHTHLDIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNIFDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWL 1040          

Query:  537 DACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTK--FALVSSSSRQWKLASDE----LKQVAHXXXXXXXXXXXXXXDNASKSMKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVN--KFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSI--LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQ----WNITPVAYFIQ------NLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNH----------YSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKE-PYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSI-YRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKE------RKISG---ESQDTPIEMKLKYNLSEENLDADEFLRKISLSS 3602
            + C +E  ++ A N+   +  C++ + S+K  FPTFART PP ++  KS++AL+  F+WT+  F  +  +S Q++  ++     L       + I  +    +        + +++ T    RIY+I+    E +  +  +    I + G+Y ++ +  +  +  K E Y + +      +L   +     A +S L +       +   ++  A      N       F  P  +     +  ++A   + +D   ++ KA+  +        NG+ I+  I    ++S  G +VY+D++GDA GN+TV +   +  G+      + PV  FI       +++  LP   +F    I W+ G  P   P+CGF  E C      ++ ++    ++  +L  LV  R W  EQ+L +LLWK+DF++V I +   E +    +  R++ NH          +  +   +      P +  +    FT IG YKG + +IK +  KS+++TR+ ++E++  +D   +N+   IG C DPPNICI++ YC+RGSLKDIL N+D+ LD +F+AS++ D+I+G+IYLHDS I +HG L TS CL+DSRW++++T FGL + +       ++  H + A+    KLL+++PE L++ P  +  G+Q+GD YSF I+ +E+  + GP+G     P    + + + ++  +    S++P+  ET   + V +CL ECW +  E RPDFK IR  L+PL KG+R NIFDNM+ +MEKYA NLE LV++RT QL EEKKK + LL  MLP+ V +QLK G  V PEHY  V+IYFSDIVGFT++SA  TP++VV  LNDLYT FDSII  YDVYKVETIGDAYMVVSGLP+RN DLHA EIA++SLHLL A+  F IRHRP   L LRIGIHSGP  AGVVGLKMPRYCLFGDTVNTASRME++G  LKIH S + + LLD LGGY   +RG I +KGKGD  TY+L  ED   R  R  +   +       + I G   ++Q+   E  ++ +L ++NL  +   R  SL S
Sbjct:  122 ETCVHEGRMAAAFNLPMISYYCTHRDPSNKADFPTFARTRPPDTQISKSVVALLLAFNWTQVSFLYLDDASGQYQPVAETILSTLTDAGVSIRDIRTWNTIYHHGFMDNPFEALVEQTYANTRIYLILGHYYEHVGLMVSLQRRGILSKGDYFVVGIDIEQYDPAKPEKYLRGL------LLEDVEPLAVQAFQSYLGI-------VPTASVSFATFANEVNKYMERPPFNFPNPLGPFGGVKQISAEAAYLYDAVHLYAKALMEVLDSGGRPRNGSAIVAAIKGSRYRSAMGYHVYIDENGDAAGNYTVLARGSVRNGRNQTVLGLRPVGTFIHRNSSLSSISKALPNLKLF--SPIDWVGGTRPAAAPRCGFGGEKCVNYTGEISAAIAGGALLLLSLVSLVLYRNWRYEQELDSLLWKIDFREVQIHE--NEREQQSQKQTRHLLNHLPRRLPPQSTHPLIRTSQVSLSSNPDADFRYTTIFTPIGLYKGQLYAIKKVRKKSVDITREMKKELKLLRDARHDNICAFIGACTDPPNICIISEYCTRGSLKDILENEDVKLDNMFIASMVADIIRGVIYLHDSPIRFHGALCTSNCLVDSRWVVKLTDFGLFAFKQGIEDSSTDMQH-MSAK--CLKLLYRAPELLRQGPSSLVMGTQRGDAYSFGILLYEMHVRRGPFGETGLTPMQCLQKVLQPQDYLNPYRPSLQPL--ETAF-DCVSECLRECWAERPEDRPDFKTIRTKLRPLRKGMRPNIFDNMMAMMEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPRCVADQLKKGHKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIGDAYMVVSGLPLRNGDLHAAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMKGKGDQRTYWLLGEDEEARTRRTYERSQRRGSRALNKFIQGTIKQAQEQANEYGIRSSLKQKNLPRNSLTRSSSLES 1161          

Query:  537 DACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTK--FALVSSSSRQWKLASDE----LKQVAHXXXXXXXXXXXXXXDNASKSMKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVN--KFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSI--LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQ----WNITPVAYFIQ------NLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKE-PYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSI-YRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKE------RKISG---ESQDTPIEMKLKYNLSEENLDADEFLRKISLSS 3602
            + C +E  ++ A N+   +  C++ + S+K  FPTFART PP ++  KS++AL+  F+WT+  F  +  +S Q++  ++     L       + I  +    +        + +++ T    RIY+I+    E +  +  +    I + G+Y ++ +  +  +  K E Y + +      +L   +     A +S L +       +   ++  A      N       F  P  +     +  ++A   + +D   ++ KA+  +        NG+ I+  I    ++S  G +VY+D++GDA GN+TV +   +  G+      + PV  FI       +++  LP   +F    I W+ G  P   P+CGF  E C      ++ ++    ++  +L  LV  R W  EQ+L +LLWK+DF++V I +     +  + ++ +   + +  +   +      P +  +    FT IG YKG + +IK +  KS+++TR+ ++E++  +D   +N+   IG C DPPNICI++ YC+RGSLKDIL N+D+ LD +F+AS++ D+I+G+IYLHDS I +HG L TS CL+DSRW++++T FGL + +       ++  H + A+    KLL+++PE L++ P  +  G+Q+GD YSF I+ +E+  + GP+G     P    + + + ++  +    S++P+  ET   + V +CL ECW +  E RPDFK IR  L+PL KG+R NIFDNM+ +MEKYA NLE LV++RT QL EEKKK + LL  MLP+ V +QLK G  V PEHY  V+IYFSDIVGFT++SA  TP++VV  LNDLYT FDSII  YDVYKVETIGDAYMVVSGLP+RN DLHA EIA++SLHLL A+  F IRHRP   L LRIGIHSGP  AGVVGLKMPRYCLFGDTVNTASRME++G  LKIH S + + LLD LGGY   +RG I +KGKGD  TY+L  ED   R  R  +   +       + I G   ++Q+   E  ++ +L ++NL  +   R  SL S
Sbjct:  122 ETCVHEGRMAAAFNLPMISYYCTHRDPSNKADFPTFARTRPPDTQISKSVVALLLAFNWTQVSFLYLDDASGQYQPVAETILSTLTDAGVSIRDIRTWNTIYHHGFMDNPFEALVEQTYANTRIYLILGHYYEHVGLMVSLQRRGILSKGDYFVVGIDIEQYDPAKPEKYLRGL------LLEDVEPLAVQAFQSYLGI-------VPTASVSFATFANEVNKYMERPPFNFPNPLGPFGGVKQISAEAAYLYDAVHLYAKALMEVLDSGGRPRNGSAIVAAIKGSRYRSAMGYHVYIDENGDAAGNYTVLARGSVRNGRNQTVLGLRPVGTFIHRNSSLSSISKALPNLKLF--SPIDWVGGTRPAAAPRCGFGGEKCVNYTGEISAAIAGGALLLLSLVSLVLYRNWRYEQELDSLLWKIDFREVQIHE-----NEREQQSQKQTRSTHPLIRTSQVSLSSNPDADFRYTTIFTPIGLYKGQLYAIKKVRKKSVDITREMKKELKLLRDARHDNICAFIGACTDPPNICIISEYCTRGSLKDILENEDVKLDNMFIASMVADIIRGVIYLHDSPIRFHGALCTSNCLVDSRWVVKLTDFGLFAFKQGIEDSSTDMQH-MSAK--CLKLLYRAPELLRQGPSSLVMGTQRGDAYSFGILLYEMHVRRGPFGETGLTPMQCLQKVLQPQDYLNPYRPSLQPL--ETAF-DCVSECLRECWAERPEDRPDFKTIRTKLRPLRKGMRPNIFDNMMAMMEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPRCVADQLKKGHKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIGDAYMVVSGLPLRNGDLHAAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMKGKGDQRTYWLLGEDEEARTRRTYERSQRRGSRALNKFIQGTIKQAQEQANEYGIRSSLKQKNLPRNSLTRSSSLES 1148          

Query: 1239 LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-----EQKLSNLLWKVDFKDVTITD---VLPEYDNNKPRNYRNIDNHYSFLVAD-EFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPW---GSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            L + +FH  D  M++  A+++   R+ S   G  + K ++++++  VTGL V +D++GD E +F +   T+ +TG + I  V       N +  +  + PG ++ W+ G PP   P+CGF N+N       + +   + ++V     ++V +  +I      E +L+  LW+V ++D+ +++   VL    +    + R   N+ S L  D  F+              + K G YKG I +IK++N K IELTRK   E++  +D+  E+L R IG C+DPPNICILT YC RGSL+D++ ++ I LD +F  SL+ D++KGM +LH+S I  HGNL++S C++DSR++L+IT +GL+S    S  D        D   +Y + LW +PE L+   P + G+QKGD+YSF II  EL    G +   G    P    EII ++          +RP++        +   +  CW +    RPDF  I+V+L+    G  SNI DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+ V  E +  VTIYFSDIVGFT+LSA STPMEVV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LHA EIA +SL LL+A+ SF IRHRPN  L+LRIGIHSGP  AGVVGLKMPRYCLFGDTVNTASRME+ GEALKIH S  T+ +L     + L  RG++E+KGKG M TY+L  E
Sbjct:  353 LISGSFH--DGVMLYSHALNDTMDRSGSRPPGDVVNKRMWNRTYHGVTGL-VQLDENGDREIDFALWDMTDTKTGDYQIVSV------YNGSQKQMILEPGMKVHWLKGRPPPDIPECGFKNDNPACLAKTVTMHQMISIVVCFIFIIIVTVTVFIYRKLKLENELTAQLWRVHWEDIQMSNTEKVLRRACSKLTISLRG-SNYGSLLTMDGNFQ-------------IYAKTGYYKGNITAIKYVNKKRIELTRKVLFELKHMRDVQNEHLTRFIGACIDPPNICILTEYCPRGSLQDLMESEGITLDWMFRYSLINDIVKGMAFLHNSVIVSHGNLKSSNCVVDSRFVLKITDYGLESFHKDSNLD--------DVHAFYARQLWTAPELLRADNPPACGTQKGDVYSFGIILQELALLKGVFYLEGPCLSP---KEIIERV---VEGRWPYLRPLLCPQSHSEEMGQLMLRCWSEDVNERPDFSQIKVLLRKNNCGYGSNILDNLLSRMEQYANNLEELVEERTQAYHEEKRKAEALLYQILPHSVAEQLKRGEMVQAEAFDSVTIYFSDIVGFTALSAESTPMEVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIARMSLALLEAVHSFRIRHRPNLQLRLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHVSEATRAVLQEFNCFQLELRGDVEMKGKGRMRTYWLLGE 1061          

Query: 1239 LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-----EQKLSNLLWKVDFKDVTITD---VLPEYDNNKPRNYRNIDNHYSFLVAD-EFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPW---GSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            L + +FH  D  M++  A+++   R+ S   G  + K ++++++  VTGL V +D++GD E +F +   T+ +TG + I  V       N +  +  + PG ++ W+ G PP   P+CGF N+N       + +   + ++V     ++V +  +I      E +L+  LW+V ++D+ +++   VL    +    + R   N+ S L  D  F+              + K G YKG I +IK++N K IELTRK   E++  +D+  E+L R IG C+DPPNICILT YC RGSL+D++ ++ I LD +F  SL+ D++KGM +LH+S I  HGNL++S C++DSR++L+IT +GL+S    S  D        D   +Y + LW +PE L+   P + G+QKGD+YSF II  EL    G +   G    P    EII ++          +RP++        +   +  CW +    RPDF  I+V+L+    G  SNI DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+ V  E +  VTIYFSDIVGFT+LSA STPMEVV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LHA EIA +SL LL+A+ SF IRHRPN  L+LRIGIHSGP  AGVVGLKMPRYCLFGDTVNTASRME+ GEALKIH S  T+ +L     + L  RG++E+KGKG M TY+L  E
Sbjct:  353 LISGSFH--DGVMLYSHALNDTMDRSGSRPPGDVVNKRMWNRTYHGVTGL-VQLDENGDREIDFALWDMTDTKTGDYQIVSV------YNGSQKQMILEPGMKVHWLKGRPPPDIPECGFKNDNPACLAKTVTMHQMISIVVCFIFIIIVTVTVFIYRKLKLENELTAQLWRVHWEDIQMSNTEKVLRRACSKLTISLRG-SNYGSLLTMDGNFQ-------------IYAKTGYYKGNITAIKYVNKKRIELTRKVLFELKHMRDVQNEHLTRFIGACIDPPNICILTEYCPRGSLQDLMESEGITLDWMFRYSLINDIVKGMAFLHNSVIVSHGNLKSSNCVVDSRFVLKITDYGLESFHKDSNLD--------DVHAFYARQLWTAPELLRADNPPACGTQKGDVYSFGIILQELALLKGVFYLEGPCLSP---KEIIERV---VEGRWPYLRPLLCPQSHSEEMGQLMLRCWSEDVNERPDFSQIKVLLRKNNCGYGSNILDNLLSRMEQYANNLEELVEERTQAYHEEKRKAEALLYQILPHSVAEQLKRGEMVQAEAFDSVTIYFSDIVGFTALSAESTPMEVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIARMSLALLEAVHSFRIRHRPNLQLRLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHVSEATRAVLQEFNCFQLELRGDVEMKGKGRMRTYWLLGE 1061          

Query: 1221 TMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-----EQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNI--DNHYSFLVAD-EFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLK-EPYPMSRGSQKGDIYSFAIIFHELTHQTGPW---GSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            T+  S++   +   +D  M++  A++     +    +G  + K ++++++  VTGL V +D++GD E +F +    ++ TG + I  V       N T  +  + PG  I W  G  P   P CGF NEN       +A+   + +++   L ++  +  +I      E++L   LW++ + D+ ++ +     +   +   ++   N+ S L  D  F+              F K G +KG IV+IK++N + +ELTRK   E++  +D+  E+L R IG C+DPPNICI+T YC RGSL++IL N  I LD +F  SL+ D++KGM +LH+S I  HGNL++S C++D+R++L+IT +GL SIR  S  +        DA  YY + LW +PE  + E +P   G+QKGD+YSF II  E+  + G +   G +  P    EI+ ++      E   +RP ++       +   +  CW +    RP+F  I V+L+   +  RSNI DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTSLSA STP++VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LH  EIA +SL LL+A+K+F IRHRP+E LKLRIGIHSGP  AGVVGLKMPRYCLFGDTVNT+SRME+ GE LKIH SS T+ +L     + L  RG++E+KGKG M TY+L  E
Sbjct:   96 TVDDSLMNIISGGFYDGLMLYCHALNESLSDSHERPSGESVSKRMWNRTYYGVTGL-VQIDENGDRETDFALWDMADINTGDFQIVAV------YNGTQKEMNILPGMAIQWPGGKVPMDVPTCGFKNENPACRARTIAMHQMISIVLFLILIIIFTVTVFIYRKLKLEKELVAQLWRISWDDIQMSHLEKALRSTGSKLTLSLRGSNYGSLLTTDGNFQ-------------VFAKTGYFKGNIVAIKYINRRRVELTRKVLFELKHMRDVQNEHLTRFIGACIDPPNICIVTEYCPRGSLQNILENDSITLDWMFKYSLISDIVKGMAFLHNSVIVSHGNLKSSNCVVDNRFVLKITDYGLSSIRTESDTE--------DAHSYYARKLWLAPELSRMECFPPG-GTQKGDVYSFGIILQEVALRRGVFYLEGDLLSP---KEIVDRV---ALGEWPYLRPSLNPQAHSEELGQLMQRCWAEEPSDRPEFSHISVLLRKQNREHRSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSLSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREIARMSLALLEAVKTFKIRHRPDEQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVSSATRAVLQEFNCFQLELRGDVEMKGKGKMRTYWLLGE 812          

Query: 1245 AATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFS--NENCRLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNV 3452
            A  FH  D  +++ KA+        S+ +G  I   + ++    VTGL V +D+      +F++ + T +++GQ+ I      + + N T  +    P  +I W  G PP   P CGFS   E+    L I+A+   + +I+ G    L+  +  + E++L+ +LW++ ++++             P  Y          ++    S     ++    + F K G +KG +V+IK +N K IELTR+   E++  +D+   +L R IG C+DPPNICI+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM YLH+S I  HGNL++S C++DSR++L+IT +GL S R +   +        D+   Y K LW +PE L       +G+QKGD+YSF II  E+  + GP+       +  EII+K++N    +    RP  D ++    +   +  CW +    RPDF  I+V +    K  + + +  +L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTS+SA STP++VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LHA EIA +SL LL+ +K+F IRHRPN+ L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+TGEAL+IH SS TK +LD  G + L  RG++E+KGKG M TY+L  E  +V
Sbjct:  344 AGCFH--DGFVLYAKALSEALADGVSQNDGINITARMQNRRLWGVTGL-VSIDQKNARFTDFSLWAMTNLKSGQYAI------VGHYNGTSKEILWSPTEKIQWPKGCPPLDYPPCGFSPCKEDHLPVLGIVAVGSGLALIIFGISSFLIYRKLKL-EKELAGMLWRIRWEELQF---------ESPNKYHKRAGS-RLTLSQRGSSYGSLITAHGKYQLFAKTGYFKGNLVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENESINLDWMFRYSLINDIVKGMNYLHNSYIGSHGNLKSSNCVVDSRFVLKITDYGLASFRSSCENE--------DSHALYAKKLWTAPELLIYDRHPPQGTQKGDVYSFGIILQEIALRNGPFYVEGMDLSPKEIIQKVRN---GQKPYFRPTTDNSRHCEELTILMEGCWSEDPAERPDFSHIKVFIAKFNKQHQYSQY--LLSRMEQYANNLENLVEERTQAYLEEKRKAENLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSMSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIAGMSLALLEQVKTFKIRHRPNDQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESTGEALRIHMSSATKEVLDEFGYFELQLRGDVEMKGKGKMRTYWLLGEKTDV 1048          

Query: 1221 TMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-----EQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNI--DNHYSFLVAD-EFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLK-EPYPMSRGSQKGDIYSFAIIFHELTHQTGPW---GSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            T+  S++   +   +D  M++  A++     +    +G  + K ++++++  VTGL V +D++GD E +F +    ++ TG + I  V       N T  +  + PG  I W  G  P   P CGF NEN       +A+   + +++   L ++  +  +I      E++L   LW++ + D+ ++ +     +   +   ++   N+ S L  D  F+              F K G +KG IV+IK++N + +ELTRK   E++  +D+  E+L R IG C+DPPNICI+T YC RGSL++IL N  I LD +F  SL+ D++KGM +LH+S I  HGNL++S C++D+R++L+IT +GL SIR  S  +        DA  YY + LW +PE  + E +P   G+QKGD+YSF II  E+  + G +   G +  P    EI+ ++      E   +RP ++       +   +  CW +    RP+F  I V+L+   K  RS    +  +++ +YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTSLSA STP++VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LH  EIA +SL LL+A+K+F IRHRP+E LKLRIGIHSGP  AGVVGLKMPRYCLFGDTVNT+SRME+ GE LKIH SS T+ +L     + L  RG++E+KGKG M TY+L  E
Sbjct:  349 TVDDSLMNIISGGFYDGLMLYCHALNESLSDSHERPSGESVSKRMWNRTYYGVTGL-VQIDENGDRETDFALWDMADINTGDFQIVAV------YNGTQKEMNILPGMAIQWPGGKVPMDVPTCGFKNENPACRARTIAMHQMISIVLFLILIIIFTVTVFIYRKLKLEKELVAQLWRISWDDIQMSHLEKALRSTGSKLTLSLRGSNYGSLLTTDGNFQ-------------VFAKTGYFKGNIVAIKYINRRRVELTRKVLFELKHMRDVQNEHLTRFIGACIDPPNICIVTEYCPRGSLQNILENDSITLDWMFKYSLISDIVKGMAFLHNSVIVSHGNLKSSNCVVDNRFVLKITDYGLSSIRTESDTE--------DAHSYYARKLWLAPELSRMECFPPG-GTQKGDVYSFGIILQEVALRRGVFYLEGDLLSP---KEIVDRV---ALGEWPYLRPSLNPQAHSEELGQLMQRCWAEEPSDRPEFSHISVLLR---KQNRS--VPHYSIVLSQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSLSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREIARMSLALLEAVKTFKIRHRPDEQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVSSATRAVLQEFNCFQLELRGDVEMKGKGKMRTYWLLGE 1060          

Query: 1623 LNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPG---NATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMIT 3422
            L I+AL   + +++ G    L+ +R  + E++L+++LW++ ++++           N  R ++   +  +  L    + S        +I   F   G +KG +V+IK +N K IELTR+   E++  +D+   +L R +G C+DPPNICI+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM +LH S I  HGNL++S C++DSR++L+IT +GL S R +   D        DA   Y K LW +PE L+   P + G+QKGD+YSF II  E+  + G     Y  G   +  EI++K++N    +    RP +D +     +   +  CW +    RPDF  I+  +    K   ++I DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTS+SA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LH  EIA +SL LL+A+++F IRHRPN  L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEAL+IH SS TK +LD    + L  RG+IE+K K  +++
Sbjct:  105 LAIVALGAGLTLLIFGMSSFLI-LRKLMLEKELASMLWRIRWEELQF--------GNSERYHKTAGSRLTLSLRGSSYGSLMTAHGKYQI---FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFLGACIDPPNICIVTEYCPRGSLQDILENESINLDWMFRNSLINDIVKGMCFLHRSIIGSHGNLKSSNCVVDSRFVLKITDYGLASFRSSCEAD--------DAYALYAKKLWTAPELLRMTRPPAPGTQKGDVYSFGIILQEIALRNG---CFYIQGMDLSPKEIVQKVRN---GQRPYFRPTVDISCHSEELGILMDRCWAEEPLDRPDFNQIKAYICKFNKEGSTSILDNLLSRMEQYANNLEKLVEERTQAYLEEKRKAENLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSMSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHTREIARMSLALLEAVRTFKIRHRPNTQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALRIHISSATKEVLDEFSCFQLELRGDIEMKVKIPLVS 682          

Query: 1710 EQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGK 3407
            E++L+++LW++ ++++           N  R ++   +  +  L    + S        +I   F   G +KG +V+IK +N K IELTR+   E++  +D+   +L R +G C+DPPNICI+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM +LH S I  HGNL++S C++DSR++L+IT +GL S R +   D        DA   Y K LW +PE L+   P + G+QKGD+YSF II  E+  + G +       +  EI++K++N    +    RP +D +     +   +  CW +    RPDF  I+  +    K   ++I DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTS+SA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LH  EIA +SL LL+A+++F IRHRPN  L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEAL+IH SS TK +LD    + L  RG+IE+K K
Sbjct:    3 EKELASMLWRIRWEELQF--------GNSERYHKTAGSRLTLSLRGSSYGSLMTAHGKYQI---FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFLGACIDPPNICIVTEYCPRGSLQDILENESINLDWMFRNSLINDIVKGMCFLHRSIIGSHGNLKSSNCVVDSRFVLKITDYGLASFRSSCEAD--------DAYALYAKKLWTAPELLRMTRPPAPGTQKGDVYSFGIILQEIALRNGCFYIQGMDLSPKEIVQKVRN---GQRPYFRPTVDISCHSEELGILMDRCWAEEPLDRPDFNQIKAYICKFNKEGSTSILDNLLSRMEQYANNLEKLVEERTQAYLEEKRKAENLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSMSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHTREIARMSLALLEAVRTFKIRHRPNTQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALRIHISSATKEVLDEFSCFQLELRGDIEMKVK 547          

Query: 1623 LNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPG---NATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGK 3407
            L I+AL   + +++ G    L+ +R  + E++L+++LW++ ++++           N  R ++   +  +  L    + S        +I   F   G +KG +V+IK +N K IELTR+   E++  +D+   +L R +G C+DPPNICI+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM +LH S I  HGNL++S C++DSR++L+IT +GL S R +   D        DA   Y K LW +PE L+   P + G+QKGD+YSF II  E+  + G     Y  G   +  EI++K++N    +    RP +D +     +   +  CW +    RPDF  I+  +    K   ++I DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTS+SA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LH  EIA +SL LL+A+++F IRHRPN  L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEAL+IH SS TK +LD    + L  RG+IE+K K
Sbjct:  133 LAIVALGAGLTLLIFGMSSFLI-LRKLMLEKELASMLWRIRWEELQF--------GNSERYHKTAGSRLTLSLRGSSYGSLMTAHGKYQI---FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFLGACIDPPNICIVTEYCPRGSLQDILENESINLDWMFRNSLINDIVKGMCFLHRSIIGSHGNLKSSNCVVDSRFVLKITDYGLASFRSSCEAD--------DAYALYAKKLWTAPELLRMTRPPAPGTQKGDVYSFGIILQEIALRNG---CFYIQGMDLSPKEIVQKVRN---GQRPYFRPTVDISCHSEELGILMDRCWAEEPLDRPDFNQIKAYICKFNKEGSTSILDNLLSRMEQYANNLEKLVEERTQAYLEEKRKAENLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSMSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHTREIARMSLALLEAVRTFKIRHRPNTQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALRIHISSATKEVLDEFSCFQLELRGDIEMKVK 705          

Query: 1710 EQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMIT 3422
            E++L+++LW++ ++++           N  R ++   + Y  L+    +            + F   G +KG +V+IK +N K IELTR+   E++  +D+   +L R +G C+DPPNICI+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM +LH S I  HGNL++S C++DSR++L+IT +GL S R +   D        DA   Y K LW +PE L+   P + G+QKGD+YSF II  E+  + G +       +  EI++K++N    +    RP +D +     +   +  CW +    RPDF  I+  +    K   ++I DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTS+SA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LH  EIA +SL LL+A+++F IRHRPN  L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEAL+IH SS TK +LD    + L  RG+IE+K K  +++
Sbjct:   65 EKELASMLWRIRWEELQF--------GNSERYHKTRGSSYGSLMTAHGKY-----------QIFANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFLGACIDPPNICIVTEYCPRGSLQDILENESINLDWMFRNSLINDIVKGMCFLHRSIIGSHGNLKSSNCVVDSRFVLKITDYGLASFRSSCEAD--------DAYALYAKKLWTAPELLRMTRPPAPGTQKGDVYSFGIILQEIALRNGCFYIQGMDLSPKEIVQKVRN---GQRPYFRPTVDISCHSEELGILMDRCWAEEPLDRPDFNQIKAYICKFNKEGSTSILDNLLSRMEQYANNLEKLVEERTQAYLEEKRKAENLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSMSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHTREIARMSLALLEAVRTFKIRHRPNTQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALRIHISSATKEVLDEFSCFQLELRGDIEMKVKIPLVS 605          

Query: 1710 EQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNV 3452
            E++L+++LW++ ++++           N  R ++   +  +  L    + S        +I   F   G +KG +V+IK +N K IELTR+   E++  +D+   +L R +G C+DPPNICI+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM +LH S I  HGNL++S C++DSR++L+IT +GL S R +   D        DA   Y K LW +PE L+   P + G+QKGD+YSF II  E+  + G +       +  EI++K++N    +    RP +D +     +   +  CW +    RPDF  I+  +    K   ++I DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTS+SA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LH  EIA +SL LL+A+++F IRHRPN  L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEAL+IH SS TK +LD    + L  RG+IE+K K  ++    +S    V
Sbjct:   88 EKELASMLWRIRWEELQF--------GNSERYHKTAGSRLTLSLRGSSYGSLMTAHGKYQI---FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFLGACIDPPNICIVTEYCPRGSLQDILENESINLDWMFRNSLINDIVKGMCFLHRSIIGSHGNLKSSNCVVDSRFVLKITDYGLASFRSSCEAD--------DAYALYAKKLWTAPELLRMTRPPAPGTQKGDVYSFGIILQEIALRNGCFYIQGMDLSPKEIVQKVRN---GQRPYFRPTVDISCHSEELGILMDRCWAEEPLDRPDFNQIKAYICKFNKEGSTSILDNLLSRMEQYANNLEKLVEERTQAYLEEKRKAENLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSMSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHTREIARMSLALLEAVRTFKIRHRPNTQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALRIHISSATKEVLDEFSCFQLELRGDIEMKVKIPLVVTHTQSHRARV 647          

Query: 1239 LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLE------LNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLK-EPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPG---NATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            L A  F  +D  +++ + ++   Q   +  +G +I++++  + +  VTGL V MDK+ D E +F + +  ++++G  +  P A++     +   K   + GR I W+ G PP   P C F  ++   +      L I+AL   V  I+ G    L+  R  + E++L+++LW++ ++++           N  R ++   +  +  L    + S        +I   F   G +KG +V+IK +N K IELTR+   E++  +D+   +L R IG C+DPPNICI+T YC RGSL+DIL N  I LD +F  SL+ DL+KGM +LH+S I+ HG+L++S C++DSR++L+IT +GL S R  +  D        D+   Y K LW +PE L   P P + G QK D+YSFAII  E+  ++GP+   Y  G   +  EI++K++N    +    RP ID TQ+   +   +  CW      RPDF  I+  ++   K   ++I DN+LL ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFT+LSA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP RN   HA EIA ++L LL A+ SF IRHRP++ L+LRIG+H+GP  AGVVGLKMPRYCLFGDTVNTASRME+ G+ALKIH SS TK  LD LG + L  RG++E+KGKG M TY+L  E
Sbjct:  332 LIAGCF--YDGILLYAQVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGL-VVMDKNNDRETDFVLWAMGDLDSG--DFQPAAHY-----SGAEKQIWWTGRPIPWVKGAPPLDNPPCAFDLDDPSCDKTPLSTLAIVALGTGVTFIMFGVSSFLI-FRKLMLEKELASMLWRIRWEELQF--------GNSDRYHKGAGSRLTLSLRGSSYGSLMTAHGKYQI---FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPD--------DSHALYAKKLWTAPELLSGNPLPTT-GMQKADVYSFAIILQEIALRSGPF---YLEGLDLSPKEIVQKVRN---GQRPYFRPSIDRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGE 1039          

Query: 1248 ATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNEN--CRLE----LNILALSVCVCVIVAGALFLLVAI---RYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPR-NYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPG---NATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            A+FH  D  +++ +A+     +  +  +G  I + ++++SF+ VTG  + +D++GD + +F++    + ETG + +      + N N T  +       ++ W  G+PP   PKCGF NE+  C  +    L +LAL   + ++     FL+V+    R    E++L + LW+V ++D+  + +     +   R       ++Y  L+  E +            + F K   YKG +V++K +N K IELTRK   E++  +D+  E+L R +G C DPPNICILT YC RGSL+DIL N+ I LD +F  SL  D++KGM++LH+  I  HGNL++S C++D R++L+IT +GL+S R   P+      H+L A+K     LW +PE L+   P +RGSQ GD+YSF II  E+  ++G     Y  G   +  EII ++   T  E    RP +D       +   +  CW +  + RP F+ IR+ L+   K   SNI DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFT+LSA STPM+VV +LNDLYT FD++I  +DVYKVETIGDAYMVVSGLP+RN  LHA E+A ++L LL A++SF IRHRP E L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEAL+IH SSETK +L+   G+ L  RG++E+KGKG + TY+L  E
Sbjct:  347 ASFH--DGLLLYVQAVTETLAQGGTVTDGENITQRMWNRSFQGVTGY-LKIDRNGDRDTDFSLWD-MDPETGAFRV------VLNFNGTSQELMAVSEHRLYWPLGYPPPDIPKCGFDNEDPACNQDHFSTLEVLALVGSLSLVS----FLIVSFFIYRKMQLEKELVSELWRVRWEDLQPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQF-----------QVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAIGSHGNLKSSNCVVDGRFVLKITDYGLESFRDPEPEQG----HTLFAKK-----LWTAPELLRMASPPARGSQAGDVYSFGIILQEIALRSG---VFYVEGLDLSPKEIIERV---TRGEQPPFRPSMDLQSHLEELGQLMQRCWAEDPQERPPFQQIRLALRKFNKENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGQLHAREVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALRIHLSSETKAVLEEFDGFELELRGDVEMKGKGKVRTYWLLGE 1050          

Query: 1623 LNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLK-EPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPG---NATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            L I+AL   V  I+ G    L+  R  + E++L+++LW++ ++++           N  R ++   +  +  L    + S        +I   F   G +KG +V+IK +N K IELTR+   E++  +D+   +L R IG C+DPPNICI+T YC RGSL+DIL N  I LD +F  SL+ DL+KGM +LH+S I+ HG+L++S C++DSR++L+IT +GL S R  +  D        D+   Y K LW +PE L   P P + G QK D+YSFAII  E+  ++GP+   Y  G   +  EI++K++N    +    RP ID TQ+   +   +  CW      RPDF  I+  ++   K   ++I DN+LL ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFT+LSA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP RN   HA EIA ++L LL A+ SF IRHRP++ L+LRIG+H+GP  AGVVGLKMPRYCLFGDTVNTASRME+ G+ALKIH SS TK  LD LG + L  RG++E+KGKG M TY+L  E
Sbjct:   22 LAIVALGTGVTFIMFGVSSFLI-FRKLMLEKELASMLWRIRWEELQF--------GNSDRYHKGAGSRLTLSLRGSSYGSLMTAHGKYQI---FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPD--------DSHALYAKKLWTAPELLSGNPLPTT-GMQKADVYSFAIILQEIALRSGPF---YLEGLDLSPKEIVQKVRN---GQRPYFRPSIDRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGE 605          

Query: 1239 LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLE------LNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLK-EPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPG---NATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSG 3212
            L A  F  +D  +++ + ++   Q   +  +G +I++++  + +  VTGL V MDK+ D E +F + +  ++++G  +  P A++     +   K   + GR I W+ G PP   P C F  ++   +      L I+AL   V  I+ G    L+  R  + E++L+++LW++ ++++           N  R ++   +  +  L    + S        +I   F   G +KG +V+IK +N K IELTR+   E++  +D+   +L R IG C+DPPNICI+T YC RGSL+DIL N  I LD +F  SL+ DL+KGM +LH+S I+ HG+L++S C++DSR++L+IT +GL S R  +  D        D+   Y K LW +PE L   P P + G QK D+YSFAII  E+  ++GP+   Y  G   +  EI++K++N    +    RP ID TQ+   +   +  CW      RPDF  I+  ++   K   ++I DN+LL ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFT+LSA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP RN   HA EIA ++L LL A+ SF IRHRP++ L+LRIG+H+G
Sbjct:  332 LIAGCF--YDGILLYAQVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGL-VVMDKNNDRETDFVLWAMGDLDSG--DFQPAAHY-----SGAEKQIWWTGRPIPWVKGAPPLDNPPCAFDLDDPSCDKTPLSTLAIVALGTGVTFIMFGVSSFLI-FRKLMLEKELASMLWRIRWEELQF--------GNSDRYHKGAGSRLTLSLRGSSYGSLMTAHGKYQI---FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPD--------DSHALYAKKLWTAPELLSGNPLPTT-GMQKADVYSFAIILQEIALRSGPF---YLEGLDLSPKEIVQKVRN---GQRPYFRPSIDRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTG 963          

Query: 1131 IILEALGLAICHEGFNGICNLKRFTKPQQITMV-KSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEI--FDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQ---ISWISGHPPFHEPKCGFSNENCRLELNILA-LSVCVCVIVAGALFLLVA-------IRYWINEQKL----SNLLWKVDFKDVTITDVLPEYD---NNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRK--FRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQT--GPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESED 3443
            I   A G  I  +GF    + +    P Q ++  +  ++  + +  D  +++ + ++ + +      +G +++  +     + + +TG  V +D  G    +++V  Y   E+G  ++     F+  L+    +  + P R     SW  G  P ++P CGF N+ C+ +   +A ++V V  ++    FL++A       +  W    K+     +  W++ +  +T+   LP++       P + RN+ +  +   + +  S  K     ++   F  +G Y+G  V++ ++  ++    +K   R+E+    ++  EN+    GVC +PPNICI+T YC +GSL+D++ N D  +D IF  S  +D++ G+++LH S +  HGNL+ S CL+DS   L+++GFGL   ++ S      W         + +L W +PE L+       G+ +GD+YSFAI+  +L HQ   GP+  +       EII ++K+  +     +RP + E +    +   + ECWD+  E RP F  I+  L+        +I D+M+  +E YA +LE +VEERT +L  EK+K+E+LL  MLP  V EQL  G++V PEH+  VTI+FSDIVGFT L + S+P++VV++LNDLY+LFD  I  +DVYKVETIGDAYMV SGLP+RN   HA EIA+++LHLL     F I H P E LKLRIG+H+GP VAGVVG+ MPRYCLFGDTVN ASRME++   L+IH S  T   L A GGY L KRG I VKGKG+  T++L+ +D
Sbjct:  307 IAPSAYGGGIGDDGFRKQVSQELRRPPFQSSITSEDQVSPYSAYLHDALLLYAQTVEEMRKAEKDFRDGRQLISTLRAGQVTLQGITG-PVLLDSQGKRHVDYSV--YALQESGNRSL-----FLPFLHYDSFQKVIRPWRNDSNTSWPHGSLPEYKPGCGFHNDLCKTKPPTVAGMTVTVTAVIPTVTFLVLASAAAITGLMLWRLRGKVQSHPGDTWWQIRYDSITL---LPQHKLSHRGTPVSRRNVSDTSTVKASADCGSLVKRHQDEEL--FFAPVGLYQGNQVALCYIGDEAEAWVKKPTVRREVCLMCELKHENIVPFFGVCTEPPNICIVTQYCKKGSLQDVMRNSDHEIDWIFKLSFAYDIVNGLLFLHGSPLRSHGNLKPSNCLVDSHMQLKLSGFGLWEFKHGS-----TWRSYNQEATDHSELYWTAPELLRLRESPCSGTPQGDVYSFAILLRDLIHQQAHGPFEDL--EAAPEEIISRIKDPRAP--VPLRPSLLEDKGDGRIVALVRECWDESPELRPIFPSIKKTLREASPRGHVSILDSMMGKLETYANHLEEVVEERTRELVAEKRKVEKLLSTMLPSFVGEQLIAGKSVEPEHFESVTIFFSDIVGFTKLCSLSSPLQVVKLLNDLYSLFDHTIQSHDVYKVETIGDAYMVASGLPIRNGAQHADEIATMALHLLSVTTHFQIGHMPEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESSSLPLRIHVSQSTAGALLAAGGYHLQKRGTISVKGKGEQTTFWLKGKD 1080          

Query:  453 KVTKYTSLPTIMRWVNENKLDGIFQLM--DDACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQW----KLASDELKQVAHXXXXXXXXXXXXXXDNASKS-MKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTV--------SSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPG-RQISWISGHPPFHEPKCGFSNENC-RLELN---ILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQ--VPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFL 3431
            K++ Y   P  +R + + +  G+   +  D++C  EA L+ A N    + +CS+  +S+K  F TFART  P SK  KS+I+L++ F W KF++V SS   W      A  EL +  +      K+         + S + +II+ T    RIYV +   + ++DF+  + + ++  SG+Y+++ V D      E+Y  N +RVN    N  D                   P I +    ++    F  +  +   T PQ   +   I      H +D  M++ +AI  + +      +G  ++  IF++S+ S+ G +VY+D +GDAEGN+TV        S  +     + ++ PV +F  + N+ +P+F      R I W++G PP  EP CGF  E C R +L+   +++  +C  V+V     L+   RY   EQ L+ LLWKVD KDVT+ + L EY+N   +N   I    S LV  E   R           +FT I  ++G IV++K ++ KS+++TR  R+E++  +++  EN+   IG   D  ++ I T YC+RGSL+D+L+N+D+ LD +F++SL+ D++KGMIYLHDS+I  HGNLR+S CLIDSRW+ QI+ FGL  ++ A  ++P+       +E    + L  +PE L++ Y   RGSQKGD+YSF I+ +E+  + GPWG      +  EII+ +K     +    RP +  T   +P++++ CL +CWD+  E RPD + +R+ LK L  GL+ NIFDNML IMEKYA NLE LV+ERT  L EEKKK + LL +MLP+ V E LK G  V  E + CVTI FSDIVGFT L  +STP EVV+MLND YT  DSII  YDVYKVETIGDAYMVVSGLP++N   HAGEIASL+LHLL+ + +  IRH+P ET++LRIG+HSGPC AGVVG KMPRYCLFGDTVNTASRME+TG++++IH S  T  LL  +G Y  I+RG   +KGKGDM TY+L
Sbjct:   91 KMSAYRVKP--LRAMTQMREAGVTAFIGPDESCTTEALLASAWNTPMLSFKCSDPIVSNKSTFHTFARTLAPASKVSKSVISLLNAFHWNKFSIVVSSKPIWGSDVARAIQELAEARNFTISHFKYISDYIPTTKTLSQIDKIIEETYATTRIYVFIGEHIAMVDFVRGLQNRRLLESGDYIVVSVDD------EIYDSN-RRVNIMERNYLD-------------------PYIRKEKSKSLDKISFRSVIKIS-MTYPQNPHIRVPIYG---LHLYDSVMIYVRAITEVLRLGGDIYDGNLVMSHIFNRSYHSIQGFDVYIDSNGDAEGNYTVITLQNDVGSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKNDRPIQWLNGRPPLAEPLCGFHGELCPRKKLDWRYLVSGPLCALVVVVAIALLIKHYRY---EQTLAGLLWKVDMKDVTVIN-LGEYNNPTNKNIFQICRQ-SILVVGEPNKR-----------SFTNIALFRGNIVAMKKIHKKSVDITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLANEDLHLDHMFISSLVSDILKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELK-AGQEEPNK------SELELKRALCMAPELLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAY--SKEEIIQFVKCPEMLQHGVFRPALTHTHLDIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNIFDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWL 1048          

Query:  390 ITALSANFVCIQTMTIE----MKVAKVTKYTSL-PTI---MRW-------------VNENKLDGIFQLM--DDACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQWKLASDELKQVAHXXXXXXXXXXXXXXDNASKSMKEIID------------STSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVN----DNFPTAAMRSMLFLSTATPNPIILEALGLAICHEG---FNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSEL----------NGTKILKEIF-DQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWN----------ITPVAYFIQNLNNTLPKFTMFPGRQISWISG-HPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAI------RYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNH-KSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSI-YRPGNATEIIRKLKNETSNELS-SMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDAL-GGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKM 3476
            +TAL+ +    Q + I     M + +V K  +L P +   +RW             + E   DGI  +   +  C  EA +S + N+   + +C+    S     PTFART PP ++ VKS++AL+  ++W KF+++      W   +D LK  A  ++ +    K    DN  K  ++++D            +T    RIYV + +   ++DF++ M +  +   GEY++I+V D  V       K ++RV++     N    +NF   A RS+L +++  P    ++       +     FN    + R       +   SI  A   + +D   ++  A+D + +     L          NGT+++  I  ++++ S+TG  + +D++GD+EGNF+V +Y   +  +WN          + PVAYF Q   +  P++ +  G  I W SG   P  EP CGF+NE C+ +      +  V  +V G L     +      R W  E ++  LLWK+D  ++        Y  N+     +  +  S + A  + SR          +  T  G  +G +V IK L   +  +++R+  +EM+  +++  +N+N  IG  ++P  I ++T YC++GSL DI+ N+DI LD++F+ASL+ DLIKGMIY+H+SQ+ YHGNL++S C++ SRW+LQ+T FGL  +R  +  +      S+   ++Y   LW++PE L+       GSQKGD+Y+FAII +E+  + GP+G I + P    + ++KL  +  +     +  II+    P++V  C+ +CW +  E RP+F  IR  LK +  G   NI D M+ +MEKYA NLE +V ERT  L EEK K E LL RMLP+SV E+L +GQ V P  Y  VTIYFSDIVGFT++SA STP++VV  LNDLYT+FD II  YDVYKVETIGDAYMVVSGLP++N D HAGEIAS++L LL A+K   I HRPNETLKLRIG+H+GP VAGVVGL MPRYCLFGDTVNTASRME+ GEALKIH S++ K  LD L GGY   KRG + +KGKGD++T++L   + N  Q++L+ M
Sbjct:   31 LTALTGDLKTRQGLAISGALTMALDEVNKDPNLLPNVYLDLRWNDTKGDTVLATKAITEMICDGIATIFGPEGPCYVEAIVSQSRNIPMISYKCAEYRAS---AIPTFARTEPPDTQVVKSLLALLRYYAWNKFSILYEDV--WSPVADLLKDQA-TKRNMTINHKQSFIDNRVKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFARGEYMVIFV-DMMVYSEREAEKYLRRVDQITFMSNCHSTENFNQMA-RSLLVVASTPPTKDYIQFTKQVQKYSSKPPFN--LEIPRLFVESNFSKFISIYAA---YLYDSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTIIKNRTYMSITGSKIKIDQYGDSEGNFSVLAY---KPHKWNNSNNMPCNYHMVPVAYFHQGEEH--PEYKLING-SIDWPSGGEKPADEPMCGFANELCKKDDT--HYTSTVAAVVLGVLLFCSGVITMSIYRKWKIELEIEGLLWKIDPNEIK------GYSGNE---IVSSPSKVSLMSAQSYGSRW-------TNQFVTSTGRLRGAVVRIKELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASVEPTRILLVTDYCAKGSLYDIIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHELRQCAENE------SIGEHQHYRNQLWRAPELLRNHI---HGSQKGDVYAFAIIMYEIFSRKGPFGQINFEPKEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEERPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQKKLVDM 1087          

Query:  540 ACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQWKLASDELK--------QVAHXXXXXXXXXXXXXXDNASKSMKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIW-VSDKFVNKFELY--FKNIKRVNKKMLNVNDNFPTAAMRSMLFLS---TATPNPIILEALGLAICHEGFNGIC--NLKRFT---------KPQQITM-VKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNIT-------PVAYFIQNLNNTLPKFTMFPGRQISWIS------GHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTI--TDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPM-SRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIID--ETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKERKISGES 3509
             C YE  L+ ALN+      C    +SDK  +PTF RT PP  + V++II  + ++   + ++V  +  +++   + +K        ++ H+E            D+      EII  T +  RIYV      ++  F        I +SG+YVI+  V D  V   + Y     I   ++ +  +N ++      + LF +   T + N   LEAL   I   G   +   N  RF+          P    + +++ +  A+ + FD TM   +A+D          +G +++  + + +++S T      D++GD    + +     +  G    T       P+  F  N  N    F        + +         PP   P CGF  E C      L  S+   +I+ G L      R    E  L +L+WKVD+ +V    TD                 N   F + +   S     S+ + ++ F  IG+Y+G + ++  ++   I+LTR  R E++  +DM  +N+   IG C+D P+I IL  YC++GSL+DIL N DI LD +F++SL+ DL+KG++YLH S+I  HG+L++S C++D+RW+LQIT +GL   +    +D     H+  A +     LW SPEHL++   M + GS +GDIYSFAII  EL  +  P+       +  +II ++K   S E+   RPI++      P+ V   +  CW +    RP+   +R +L PL KGL+ NI DNM+ IME+Y  NLE LV+ERT +L +EK K E+LL RMLP S+  QL  G  V+PE +  V+I+FSDIVGFT+LSA+STP++VV +LNDLYTLFD+II  YDVYKVETIGDAYM+VSGLP+RN D HAG+IAS + HLL+++K F++ H+P   LKLRIGIHSG CVAGVVGL MPRYCLFGDTVNTASRME+ G AL+IH S   K +LD LGGY L  RG + + GKG++ T++L  +DP+    ++ K+K   +K++ E+
Sbjct:  119 GCTYEGRLASALNIPMIDYVCDENPVSDKSIYPTFLRTIPPSIQVVEAIILTLQRYELDQVSVVVENITKYRNIFNTMKDKFDERDYEILHEEYYAGFDPWDYEMDD---PFSEIIQRTKETTRIYVFFGDASDLRQFAMTALDEGILDSGDYVILGAVVDLEVRDSQDYHSLDYILDTSEYLNQINPDY------ARLFKNREYTRSDNDRALEALKSVIIVTGAPVLKTRNWDRFSTFVIDNALDAPFNGELELRAEIDFASVYMFDATMQLLEALDRTHAAGGDIYDGEEVVSTLLNSTYRSKTDTFYQFDENGDGVKPYVLLHLIPIPKGDGGATKDSLGMYPIGTF--NRENGQWGFEEALDEDANVLKPVWHNRDEPPLDMPPCGFHGELCTNWALYLGASIPTFLIIFGGLIGFFIYRKRAYEAALDSLVWKVDWSEVQTKATDT----------------NSQGFSMKNMVMSAISVISNAEKQQIFATIGTYRGTVCALHAVHKNHIDLTRAVRTELKIMRDMRHDNICPFIGACIDRPHISILMHYCAKGSLQDILENDDIKLDSMFLSSLIADLVKGIVYLHSSEIKSHGHLKSSNCVVDNRWVLQITDYGLNEFKKGQKQDVDLGDHAKLARQ-----LWTSPEHLRQEGSMPTAGSPQGDIYSFAIILTELYSRQEPFHE--NEMDLADIIGRVK---SGEVPPYRPILNAVNAAAPDCVLSAIRACWPEDPADRPNIMAVRTMLAPLQKGLKPNILDNMIAIMERYTNNLEELVDERTQELQKEKTKTEQLLHRMLPPSIASQLIKGIAVLPETFEMVSIFFSDIVGFTALSAASTPIQVVNLLNDLYTLFDAIISNYDVYKVETIGDAYMLVSGLPLRNGDRHAGQIASTAHHLLESVKGFIVPHKPEVFLKLRIGIHSGSCVAGVVGLTMPRYCLFGDTVNTASRMESNGLALRIHVSPWCKQVLDKLGGYELEDRGLVPMNGKGEIHTFWLLGQDPSY---KITKVKPPPQKLTQEA 1112          

Query: 1248 ATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITP---VAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-----EQKLSNLLWKVDFKDVTITDVLPEYDNNKPR-NYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            A+FH  D  +++ +A+        +  +G  I + ++++SF+ VTG  + +D  GD E +F++          W++ P       + N N T  +     GR+++W  G+PP   PKCGF NE+     + L+    + ++ + +L  ++ + ++I      E++L++ LW+V ++DV  + +     +   R       ++Y  L+  E +            + F K   YKG +V++K +N K IELTRK   E++  +D+  E+L R +G C DPPNICILT YC RGSL+DIL N+ I LD +F  SL  D++KGM++LH+  I  HGNL++S C++D R++L+IT +GL+S R   P+              Y K LW +PE L+   P  RGSQ GD+YSF II  E+  ++G +       +  EII ++   T  E    RP +        +   +  CW +  + RP F+ IR+ L+   +   SNI DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFT+LSA STPM+VV +LNDLYT FD++I  +DVYKVETIGDAYMVVSGLP+RN  LHA E+A ++L LL A++SF IRHRP E L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEALKIH SSETK +L+  GG+ L  RG++E+KGKG + TY+L  E
Sbjct:  351 ASFH--DGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGY-LKIDSSGDRETDFSL----------WDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQF-----------QVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQ---------GHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERV---TRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGE 1054          

Query: 1239 LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLE------LNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLK-EPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPG---NATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            L A  F  +D  +++ + ++   Q   +  +G +I++++  + +  VTGL V MDK+ D E +F + +  ++E+G  +  P A++     +   K   + GR I W+ G PP   P C F  ++   +      L I+AL   +  I+ G    L+  R  + E++L+++LW++ ++++           N  R ++   +  +  L    + S        +I   F   G +KG +V+IK +N K IELTR+   E++  +D+   +L R IG C+DPPNICI+T YC RGSL+DIL N  I LD +F  SL+ DL+KGM +LH+S I+ HG+L++S C++DSR++L+IT +GL S R  +  D        D+   Y K LW +PE L   P P + G QK D+YSFAII  E+  ++GP+   Y  G   +  EI++K++N    +    RP ID TQ+   +   +  CW      RPDF  I+  ++   K   ++I DN+LL ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFT+LSA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP RN   HA EIA ++L LL A+ SF IRHRP++ L+LRIG+H+GP  AGVVGLKMPRYCLFGDTVNTASRME+ G+ALKIH SS TK  LD LG + L  RG++E+KGKG M TY+L  E
Sbjct:  332 LIAGCF--YDGILLYAQVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGL-VVMDKNNDRETDFVLWAMGDLESG--DFQPAAHY-----SGAEKQIWWTGRPIPWVKGAPPLDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLI-FRKLMLEKELASMLWRIRWEELQF--------GNSDRYHKGAGSRLTLSLRGSSYGSLMTAHGKYQI---FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPD--------DSHALYAKKLWTAPELLSGNPLPTT-GMQKADVYSFAIILQEIALRSGPF---YLEGLDLSPKEIVQKVRN---GQRPYFRPSIDRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGE 1039          

Query:  534 DDACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVS----SSSRQWKLASDELKQVAHXXXXXXXXXXXXXXDNASKSMKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKN-----IKR------VNKKMLNVNDNFPTAAMRSMLFLSTATP-NPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSI-LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSY---TEMETG-QWNITPVAYF-----IQNLNNTLPKFTMF-PGRQISWISGHPPFHEPKCGFSNENC--RLELNILAL----SVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNAT--EIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERL 3467
            DD C +EA +S A N+     +CS   +SDKR F TFART PP SK  KS++AL+  F W KF LVS    +S  + + A +EL   AH   +                M  I+  T K  R+YV +   + ++DFI  +   ++ + G+YV+I V D      E+Y  N     +KR      +N+   N  D       RS+L L+ + P NP         IC E    +     F  P    +  SI +     + +D  M++ +A+  +FQ N+   NGT I+K + ++S+ SV G +VY+D +GDAEGNFTV +    TEM    + ++ PV YF       NL+  LP+F      R I W  G  P  EP CGF  E C  + +  ++A+    +V VCV +   LF+L   RY   EQKL+ LLWK+D KDVTI         N+ +N   I  H  F  A    S     SS K+   +T IG YKG IV+IK ++ KS++LTR  R+E++  +++  ENL   IG  ++  N+ ILT YC RGSL+D+L+N+D+ LD +F++SL+ D++KGMIYLHDS I  HGN R+S CLIDSRW+LQIT FGL   R     D   W     +EK   + LW++PE L+   P SRG+QKGD+YSFAI+ +E+  ++GPWG      N T  EI+  +K E  +     RP +D  +  ++VK C+ ECW +  ++RPD +F+R  LK +  GL+ NIFDNML IMEKYA NLE LV+ERT QL+EEKKK + LL RMLPKSV E LK G  V  E + CVTIYFSDIVGFT LSA STP++V+ +LN++Y+ FDSII  YDVYKVETIGDAYMVVSGLP+RN + HAGEIAS++LHLL  IK F ++HR  E L+LRIGIHSG CVAGVVG KMPRYCLFGDTVNTASRME++G A KIHTS  T  LL  LGGY   +RG I +KGKG+M TY+L +ED + R  R+
Sbjct:  153 DDTCSHEALVSAAWNLPMIGYKCSETRVSDKRVFYTFARTLPPSSKVSKSVVALLTAFGWRKFVLVSGYHPASGSEVREAIEEL-STAHGLTVTDVKLYSDYIPKNIDEMDAIVADTFKRTRVYVFVGEHIALIDFIRCLQRRKLLDKGDYVVISVDD------EIYDPNGKISIMKREYLDPFLNETWGNTED---VMGFRSVLKLTPSHPRNPNYKH-----IC-EQIKAMSAKPPFCVPYHHKIFDSISVPIQAAYLYDAVMIYARALTEVFQSNEDSRNGTAIIKRMLERSYHSVQGNDVYIDANGDAEGNFTVVALLDDTEMNGSIRLSMQPVGYFEYQSNGSNLSIALPEFKYLNAARPIQWQGGRVPLAEPFCGFYGEKCIYKTDWKLVAVVSFTTVAVCVAI---LFILKHYRY---EQKLACLLWKIDMKDVTIIPTESGESANRSKNMIQICRHSVFQSATRSASE-VVESSPKV--AYTTIGLYKGNIVAIKRIHKKSVDLTRSIRKELKQIREVRHENLITFIGASVEHGNVAILTAYCPRGSLEDVLNNEDLHLDNMFISSLVSDMLKGMIYLHDSDIISHGNFRSSNCLIDSRWVLQITDFGLHEFRVGEISD--QW-----SEKELRRSLWRAPELLRAECPPSRGTQKGDVYSFAIVLYEILGRSGPWGCT----NMTHFEILEAIKRECQD--FPFRPSLDNLEADDYVKRCMKECWAEDPDQRPDIRFVRSRLKEMQAGLKPNIFDNMLAIMEKYAYNLEGLVQERTNQLTEEKKKTDALLHRMLPKSVAEALKRGNNVEAETFDCVTIYFSDIVGFTELSALSTPLQVIDLLNEVYSCFDSIISHYDVYKVETIGDAYMVVSGLPIRNGNRHAGEIASMALHLLSKIKRFEVKHRAGELLQLRIGIHSGKCVAGVVGHKMPRYCLFGDTVNTASRMESSGCAFKIHTSHATFALLQDLGGYIFEERGLIPIKGKGEMRTYWLIAEDSSQRLARI 1127          

Query:  468 TSLPTI-MRWVNENKLDGIFQLM--DDACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQWK-LASDELKQVAHXXXXXXXXXXXXXXD-------NASKSMKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKR-------VNKKMLNVNDNFPTA-----AMRSMLFLSTATP-NPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSI-LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSY---TEMETGQWNIT--PVAYFIQNLNNT-LPKFTMFP-GRQISWISGHPPFHEPKCGFSNENC-----RLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERL 3467
            +SL T+ +R + E + +G    +  D  C  EA ++ A N+   +  C++  +SDKR + TFART  P +K  KS++AL+  FSW+ F +V      W     D +K +AH+  + +        D       N +K M  I+  T +  R+YV +   + ++DF+  +    +  +GEY++I V D      E+Y    +R       ++  +L  N++  ++     A RS+L L+ + P NP   E     IC E    I     F  P   T+  SI +     H +D   ++ +A+  +        NGT IL  I ++S+ SV G +VY+D +GDAEGNF+V +     E   G   ++  PV YF  + NNT LP+F  +   R I W+    P  EP CGF+   C     R+ + +  L     +++  A+F     RY   EQKL+ LLWK+D KDVTI     E D       RN   H   L          P  S K  + +TKIG YKG  V+IK ++ KSI+LTR  R+E++  ++M  EN+   IG C++  NICILT YC+RGSL+D+L+N+D+ LD +F++SL+ D+IKGMIYLHDS I  HGNLR+S CL+DSRW+LQI+ FGL   +    +        LD      + LW++PE L+ P    RG+QKGD+YSF I+ HE+  + GPWG+        EI+ ++K         +RP++   QV   V  C+  CWD+  E RPDF+F+RV LK +  GL+ NIFDNML IMEKYA NLE LV+ERT QL+EEKKK + LL RMLPK+V E LK G+ V  E + CVTIYFSD+VGFT LSA STP++VV++LNDLYT  DSII  YDVYKVETIGDAYMVVSGLP+RN D HAGE AS++LH+L +I+   IRHRP E LKLRIGIHSG CVAGVVGLKMPRYCLFGDTVNTASRME+TGEA KIH SS TK LLD LGGY   +RG + +KGKG+M+TY+L  ED  +R  RL
Sbjct:   41 SSLATVPIRVMTEMRDNGTVAFIGPDGTCSAEALVAAAWNLPIISYRCADKLVSDKRIYHTFARTLAPSTKISKSVVALLKAFSWSMFVVVFGQIPAWAPQVKDAIKDLAHEHGLTVTDICQFAGDYTDYIPKNIAK-MDRIVADTYQRTRVYVFVGEHIALVDFVKCLQKRGLLKNGEYIVISVDD------EIYHPERRRNIVQRDYLDPWILKRNNSSWSSEDHILAFRSVLKLTPSHPRNPKYKE-----IC-EKVRKISAEPPFCVPYHRTIFDSISVPIHAAHLYDAVTIYARALTEVLAVGQDPRNGTAILARILNRSYHSVQGHDVYIDSNGDAEGNFSVVALLHDKEEANGTLGLSMQPVGYFRYDENNTALPEFKYYDDSRPIQWVGNSRPLAEPLCGFTGHKCLKDKWRISVTLGGL---FALVLVAAIFAFKHYRY---EQKLACLLWKIDMKDVTIIST-AEAD-------RNSMLHPGQLCRQSILRSIVPEVSPK--RAYTKIGFYKGNTVAIKCIHKKSIDLTRNIRKELKQVREMRHENIITFIGACVEANNICILTAYCARGSLEDVLANEDLHLDNMFISSLIADIIKGMIYLHDSDIISHGNLRSSNCLVDSRWVLQISDFGLHEFKAGHEE--------LDESLEIKRRLWRAPELLRSPNSHPRGTQKGDVYSFGIVLHEVAGRAGPWGNTQL--TYHEIVERVKLG-----DGLRPVVIGLQVAPSVISCMQACWDEDPETRPDFRFVRVKLKEMQAGLKPNIFDNMLAIMEKYAYNLEGLVQERTNQLTEEKKKTDALLNRMLPKTVAESLKRGEPVEAESFECVTIYFSDVVGFTELSAVSTPLQVVELLNDLYTCCDSIISHYDVYKVETIGDAYMVVSGLPVRNGDRHAGETASMALHMLDSIRRLEIRHRPGEPLKLRIGIHSGQCVAGVVGLKMPRYCLFGDTVNTASRMESTGEAFKIHISSTTKELLDRLGGYTCEERGIVHIKGKGEMLTYWLIGEDRAMRLARL 1033          

Query:  534 DDACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQWKLASDELKQVAHXXXXXXXXXXXXXXDNASKSMKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSD---------KFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATP-NPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSI-LTAATFHTFDLTMMFFKAIDNIFQR-NDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMET--GQWNITPVAYFIQNLNNT-LPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSV-CVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPR---NYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERL 3467
            +  C  E  ++ A N+   A +C +  LS K  +PTFART P   K  KS+IALM  F WTK AL+  +   W   +  +K++A +  I I  E+    D  + +M +I+D T +  R+YVI+ +    ++F   +    +  +GEYV+I V +         ++V KF  Y    K  N   L   D F     R++L L+   P NP   E L      +      + K F  P ++   K   +     H +D   ++ +A+  +    N    +G  I  +I  ++FKS+ G +V++D++GD EGN+TV +     +    W I  V  F    N + +  F M     I W+ G  P  EP CGF NE C+ + +    SV CV   V   +  ++ +R+++ EQKL+ LLWK+DFK +     LPE D   P      R+  +    L+           S    R    +IG+YKGM+V++KF+N K +++ R+ ++E+Q  KD+N +N+NR +G CLD P +C+++ +CSRGSL DIL N ++ LD++F+ASL+ DLIKGMI++H+S+I  HGNL+++ CL+D+RW+LQI+ FGL S+   + +       S+D   YY  LLW +PE L+      +G+ KGD+YSFAII  E+  + GPWG    P    +II  +K+ TSN     RP          + +C+ +CW +  + RPDFK IR +LK + +GL SNIFDNM+ +MEKY+ +LE LV++RT QLSEEKKK E LLLRMLP+SV +QLK G+ V PE YS VTIYFSDIVGFT LSA S+PM++V MLNDLYTLFDSI   YDVYKVETIGDAYMVVSGLP+RN D HAGEIAS+SL LL AIK+F IRH+PNE LKLRIG+HSG CVAGVVGLKMPRYCLFGDTVNTASRME+TG ALKIH S   K +LD LGGY L +RGNI VKGKG+M TYFL SED   R  RL
Sbjct:  109 EGTCRTEGVVAAAWNLPMIAFKCPDSGLSYKVHYPTFARTQPSTFKVSKSVIALMKYFQWTKTALIVGNRTIWLETAAAVKELADQNDISITVERIFE-DKFTTAMNDIVDETHQHTRVYVILGNRFASINFARYLYDSGLQKNGEYVVISVQEQPFQPSNIKRYVAKFPYY----KSDNDLTLERIDAF-----RAVLTLALRPPSNPNYEEFL------DKTRNYSSEKPFNAPHKMIPGKKFPVPIYAAHLYDAVAIYGRALSEVLAMPNGKPDDGRAIFNQIRSRAFKSIQGHDVFIDENGDTEGNYTVLTVQRDPSFPRGWTIRSVGAFTSRDNKSAVLDFNMH--GSIQWLKGKVPVCEPPCGFRNEKCQSDFDWTVASVGCVFAAVFVVIVSVLGLRHYLYEQKLAKLLWKIDFKGLQ----LPESDLKSPGLKCERRDSTDSMDLLIPSSTPLAPFTESLTPFRNNI-QIGTYKGMVVAVKFINRKPVQVNREMKKELQHRKDINHDNINRFLGACLDGPRVCVVSQFCSRGSLHDILENNNMKLDDMFIASLVLDLIKGMIFIHESRIGSHGNLKSTNCLVDTRWVLQISDFGLYSLDSHTDRR-----QSVDGLNYYKDLLWTAPELLRSANRPPQGTPKGDVYSFAIILFEVHARNGPWGDAKMP--PQDIIEHVKS-TSNVTEPFRPETHLLSCKPHIVNCIKQCWTENPDDRPDFKSIRTMLKSMQQGLHSNIFDNMIAMMEKYSNHLEDLVDDRTMQLSEEKKKTELLLLRMLPRSVADQLKRGERVSPETYSSVTIYFSDIVGFTVLSAESSPMQIVDMLNDLYTLFDSITSHYDVYKVETIGDAYMVVSGLPLRNGDNHAGEIASMSLQLLSAIKTFKIRHKPNEMLKLRIGLHSGQCVAGVVGLKMPRYCLFGDTVNTASRMESTGVALKIHISMACKLILDKLGGYQLEERGNIHVKGKGEMTTYFLLSEDTAFRSRRL 1074          

Query:  534 DDACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQWKLASDELKQVA--HXXXXXXXXXXXXXXDNASKSMKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATP-NPIILEALGLAICHEGFNGICNLKR-------FTKPQQITMVKSI-LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETG----QWNITPVAYFIQNLNNT-LPKFTMF-PGRQISWISGHPPFHEPKCGFSNENC---RLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKP---RNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERL 3467
            D  C  EA ++ A N+   +  C+++ +SDKR + TFART PP     KS++AL+  F W KF +VS  +       D +K  A  H   +  +++         + +  I+  + ++ R+YV +   + ++DF+  +   ++ + G+Y++I V D+  +         +      LN+ DN      +S+L L+ + P NP              +N IC   R       F  P    +  S+ +  +  H +D  M++ +A+  +F   +   NGT +LK I ++S+ SV G +VY+D +GDAEGN++V +  +        + ++ PV YF  N +NT LP F  F   R+I W+ G PP  EP CGF+ + C   +  + +    + +  +VAG+     A +++  EQKL+ LLWK++ +DVTI   +P  +  K    R  +         +A E   +R           +T IG YKG  V+IK ++ +S++LTR  R+E++  ++M  EN+   IG C++  N+CILT YC+RGSL+D+L+N+D+ LD +FV+SL+ D+IKGMIYLHDS+I  HGNLR+S CL+DSRW+LQI+ FGL   + A  ++P       D E    + LW++PE L+  +   RG+QKGD+YSFAI+ HE+  + GPWG+I    +  EI R+++       S +RP   +  V   V  C+  CWD+  E RPDF+F+R+ LK +  GL+ NIFDNML IMEKYA NLE LV+ERT QL+EEKKK + LL RMLPK+V E LK G  V  E + CVTIYFSDIVGFT LSA STP++VV++LNDLYT  DSII  YDVYKVETIGDAYMVVSGLP+RN D HAGEIAS++LH+L +I+   IRHRP E LKLRIGIHSG CVAGVVGLKMPRYCLFGDTVNTASRME+TGEA ++H S  TK LLD LGGY   +RG +++KGKG+M+TY+L  ED  +R  RL
Sbjct:   10 DGTCVSEALVAAAWNLPIISYRCADMAVSDKRVYHTFARTLPPSKSVSKSVVALLKAFEWDKFVIVSGPTAWAVQVKDAVKSFAEEHSMTVTSEWQFTEYIPMLKQKIDRIVADSYEKTRVYVFIGEHVALVDFVKCLQERKLLDIGDYIVISVDDQIYDPANKGSIVQRGYIDPWLNLGDN-SLLPFQSVLKLTPSHPRNP-------------EYNAICEQVRNISIKPPFCVPYHKMIFDSLTVPISAAHLYDAVMIYARALTEVFAAGEDPRNGTAVLKRILNRSYHSVQGHDVYIDNNGDAEGNYSVVALLDDSEANGSLRMSMQPVGYFQYNESNTGLPIFKYFNESRKIQWVGGKPPLGEPICGFTGKKCQEDKWRIVVALGGLALLSLVAGSF----AFKHYRYEQKLACLLWKIELRDVTI---IPTTNTEKSVLLRPGQVCRQSILRSIAPEVSPKR----------AYTNIGFYKGNTVAIKAVHKRSVDLTRNIRKELKQIREMRHENIITFIGACVENGNVCILTAYCARGSLEDVLANEDLHLDGMFVSSLVADIIKGMIYLHDSEIISHGNLRSSNCLVDSRWVLQISDFGLHEFK-AGQEEP-------DPEMEAKRKLWRAPELLRSVH-HPRGTQKGDVYSFAIVLHEVVGRAGPWGNIQL--SYQEISREVQMG-----SGLRPDTKDLDVSPSVVSCMEACWDEDPETRPDFRFVRIKLKEMQAGLKPNIFDNMLAIMEKYAYNLEGLVQERTNQLTEEKKKTDALLNRMLPKTVAESLKKGDPVEAESFECVTIYFSDIVGFTELSAVSTPLQVVELLNDLYTCCDSIISHYDVYKVETIGDAYMVVSGLPLRNGDRHAGEIASMALHMLNSIRRLEIRHRPGEPLKLRIGIHSGHCVAGVVGLKMPRYCLFGDTVNTASRMESTGEAFRVHISKTTKDLLDRLGGYQCEERGQVQIKGKGEMLTYWLVGEDRAMRLARL 963          

Query:  486 MRWVNENKLDGIFQLM--DDACDYEAALSGALNVAFFATECSNVELSDKRQFPTFARTNPPISKAVKSIIALMHKFSWTKFALVS----SSSRQWKLASDELKQVAHXXXXXXXXXXXXXXDNASKSMKEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKR------VNKKMLNVNDNFPTAAMRSMLFLSTATP-NPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSI-LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEME----TGQWNITPVAYFI-----QNLNNTLPKFTMFP-GRQISWISGHPPFHEPKCGFSNENC--RLELNILA-LSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERL 3467
            +R + E + +G    +  DD C  EA ++ A N+   + +CS+  +SDK+ F TFART PP SK  KS++AL+  F W +F +VS    +S+ + + A +EL  + H   +    +      +  + M  I+  T  + R+YV +   + ++DFI  +   ++ ++G+YV+I V D+  +      K I+R      +N+   NV+D       RS+L L+ + P NP         +C E          F  P    +  SI +     + +D  M++ +A+  +FQ N+   NGT +L+ I ++S+ S+ G +V++D +GDAEGNFTV +  + +    T + ++ PV YF       N+ + LP+F      R I W+ G  P  EP+CGF+ E C  R++   LA +S+   +++ G LF +   RY   E KL+ LLWK+D +DVTI        +NK  +   +  H  F       S     +    ++ +T IG YKG IV+IK+L  +S++LTR  R+E++  +++  ENL   IG  +D  N+ ILT Y +RGSL+D+L+N+D+ LD +FV+SL+ D++KGMIYLHDS I  HGNLR+S CLIDSRW++QIT FGL   + A P+        L       + LW++PE L++P P +RG+QKGD+YSF I+ +E+  + GPWG        +EI+R++       L   RP ++     +++  C+  CW +  ++RPD +F+RV LK +  GL+ NIFDNML IMEKYA NLE LV+ERT QL+EEKKK E LL RMLPKSV E LK G  V  E + CVTIYFSDIVGFT LSA STP++V+ +LNDLYT FDSII  YDVYKVETIGDAYMVVSGLP+RN D HAGEIAS++LHLL  I+ F I+HR  E L+LRIGIHSG CVAGVVGLKMPRYCLFGDTVNTASRME++GEA KIH S  T  LL  LGGY   +RG I +KGKG+M TY+L  EDP  R  R+
Sbjct:  116 IRVMTEMRDNGTIAFIGPDDTCSSEALVAAAWNLPMISYKCSDTRVSDKKVFFTFARTLPPSSKVSKSVVALLRAFQWHRFVVVSGTHPASASEVQEAIEELS-IIHGLTVTDIKQYSDYIPHYIEQMDNIVADTYMKTRVYVFVGEHIALIDFIKCLQRRKLLDTGDYVVISVDDEIYDP-NRRIKIIRRDYLDPFLNETWGNVSD---VMGFRSVLKLTPSHPRNPKYK-----YVC-EKIKASSAKPPFCVPYHHKIFDSISVPIQAAYLYDAVMIYARALTEVFQNNEDPRNGTAVLRRIVNRSYHSIQGYDVFIDGNGDAEGNFTVVALLDDQEMNGTLRMSMQPVGYFQYKSNGSNVPSALPEFRYLDVDRPIQWVGGKLPRAEPRCGFNGEKCIYRIDWRFLASVSLMSLIVLIGILFCVKHYRY---EHKLACLLWKIDMRDVTIIPTETTELSNK--SMIQVCRHSVFQAP---SSSLAELAESSPKRAYTDIGLYKGNIVAIKYLKKRSVDLTRSIRKELKQIREVRHENLIPFIGASVDHGNVAILTAYSARGSLEDVLANEDLHLDNMFVSSLVTDILKGMIYLHDSDIISHGNLRSSNCLIDSRWVVQITDFGLHEFK-ACPEGAETQSKKLK------RSLWRAPELLRDPSPPARGTQKGDVYSFGIVLYEIIGRRGPWGDTNI--EPSEILRQVIEVKEVPL---RPPLENLGAADYIIKCMKACWHEEPDQRPDIRFVRVRLKEMQAGLKPNIFDNMLAIMEKYAYNLEGLVQERTNQLTEEKKKTEALLHRMLPKSVAEALKRGDRVEAESFDCVTIYFSDIVGFTELSAVSTPLQVIDLLNDLYTCFDSIISHYDVYKVETIGDAYMVVSGLPIRNGDRHAGEIASMALHLLSNIRKFEIKHRQGEVLQLRIGIHSGHCVAGVVGLKMPRYCLFGDTVNTASRMESSGEAFKIHISHATYNLLQNLGGYRCEERGVIPIKGKGEMRTYWLVGEDPAQRLARI 1105          

Query: 1221 TMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-----EQKLSNLLWKVDFKDVTITD---VLPEYDNNKPRNYRNIDNHYSFLVAD-EFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            T+  S++   +   +D  M++ +A++     +    +   I + ++++++  VTGL V +DKHGD E +F +   T+  +  + I  V       N T  +    PG    W  G  P   P CGF N+N       + +   V ++V   L ++  I  +I      E++L+  LW++ ++D+ +++   VL    +    + R   N+ S L AD  F+              F K   +KG IV+IK++N K IELTRK   E++  +D+  ++L R IG C+DPPN+ I+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM +LH+S I  HGNL++S C++D+R++L+IT +GL S R  S  DP       DA  YY + LW +P+ L+   P + G+QKGDIYSF II  E+  + G     Y  G++      +      E   +RP ++       +   +  CW +    RP+F  I+V+L+   + +  +I DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTSLSA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LHA EIA +SL LL A+K+F IRHRP++ LKLRIGIHSGP  AGVVGLKMPRYCLFGDTVNT+SRME+ GE LKIH SS +  +L     + L  RG++E+KGKG M TY+L  E
Sbjct:  351 TVDDSLMNIISGGFYDGLMLYVQALNESLAESHGRPSSKSITERMWNRTYYGVTGL-VQIDKHGDRETDFALWDMTDTNSSVFQIVAV------YNGTQKQMRTLPGMAFHWPGGFIPPDMPFCGFKNDNPACIARTITMHQMVSIVVFFILVIIFTITVFIYRKLKLEKELAAQLWRISWEDMQMSNLEKVLRSAGSKLTLSLRG-SNYGSLLTADGNFQ-------------VFAKTAYFKGNIVAIKYVNRKRIELTRKVLFELKHMRDVQNDHLTRFIGACIDPPNVSIVTEYCPRGSLQDILENESITLDWMFKYSLINDIVKGMAFLHNSVIVSHGNLKSSNCVVDNRFVLKITDYGLSSFRTES--DPE------DAHSYYARKLWMAPDLLRMSNPPACGTQKGDIYSFGIILQEVALRRG---VFYIEGDSLSPKEIVDRVALGEWPYLRPTVNTQAHSEELGQLMQRCWAEEPAERPEFSHIKVLLRKQNREVSRDILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSLSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIARMSLALLDAVKTFKIRHRPDQQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVSSASHDILQEFNCFQLELRGDVEMKGKGKMRTYWLLGE 1067          

Query: 1221 TMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-----EQKLSNLLWKVDFKDVTITD---VLPEYDNNKPRNYRNIDNHYSFLVAD-EFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            T+  S++   +   +D  M++ +A++     +    +   I + ++++++  VTGL V +DKHGD E +F +   T+  +  + I  V       N T  +    PG    W  G  P   P CGF N+N       + +   V ++V   L ++  I  +I      E++L+  LW++ ++D+ +++   VL    +    + R   N+ S L AD  F+              F K   +KG IV+IK++N K IELTRK   E++  +D+  ++L R IG C+DPPN+ I+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM +LH+S I  HGNL++S C++D+R++L+IT +GL S R  S  DP       DA  YY + LW +P+ L+   P + G+QKGDIYSF II  E+  + G     Y  G++      +      E   +RP ++       +   +  CW +    RP+F  I+V+L+   + +  +I DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTSLSA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LHA EIA +SL LL A+K+F IRHRP++ LKLRIGIHSGP  AGVVGLKMPRYCLFGDTVNT+SRME+ GE LKIH SS +  +L     + L  RG++E+KGKG M TY+L  E
Sbjct:  351 TVDDSLMNIISGGFYDGLMLYVQALNESLAESHGRPSSKSITERMWNRTYYGVTGL-VQIDKHGDRETDFALWDMTDTNSSVFQIVAV------YNGTQKQMRTLPGMAFHWPGGFIPPDMPFCGFKNDNPACIARTITMHQMVSIVVFFILVIIFTITVFIYRKLKLEKELAAQLWRISWEDMQMSNLEKVLRSAGSKLTLSLRG-SNYGSLLTADGNFQ-------------VFAKTAYFKGNIVAIKYVNRKRIELTRKVLFELKHMRDVQNDHLTRFIGACIDPPNVSIVTEYCPRGSLQDILENESITLDWMFKYSLINDIVKGMAFLHNSVIVSHGNLKSSNCVVDNRFVLKITDYGLSSFRTES--DPE------DAHSYYARKLWMAPDLLRMSNPPACGTQKGDIYSFGIILQEVALRRG---VFYIEGDSLSPKEIVDRVALGEWPYLRPTVNTQAHSEELGQLMQRCWAEEPAERPEFSHIKVLLRKQNREVSRDILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSLSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIARMSLALLDAVKTFKIRHRPDQQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVSSASHDILQEFNCFQLELRGDVEMKGKGKMRTYWLLGE 1067          

Query: 1221 TMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-----EQKLSNLLWKVDFKDVTITD---VLPEYDNNKPRNYRNIDNHYSFLVAD-EFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            T+  S++   +   +D  M++ +A++     +    +   I + ++++++  VTGL V +DKHGD E +F +   T+  +  + I  V       N T  +    PG    W  G  P   P CGF N+N       + +   V ++V   L ++  I  +I      E++L+  LW++ ++D+ +++   VL    +    + R   N+ S L AD  F+              F K   +KG IV+IK++N K IELTRK   E++  +D+  ++L R IG C+DPPN+ I+T YC RGSL                      ++ GM +LH+S I  HGNL++S C++D+R++L+IT +GL S R  S  DP       DA  YY + LW +P+ L+   P + G+QKGDIYSF II  E+  + G +   Y  G++      +      E   +RP ++       +   +  CW +    RP+F  I+V+L+   + +  +I DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTSLSA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LHA EIA +SL LL A+K+F IRHRP++ LKLRIGIHSGP  AGVVGLKMPRYCLFGDTVNT+SRME+ GE LKIH SS +  +L     + L  RG++E+KGKG M TY+L  E
Sbjct:  331 TVDDSLMNIISGGFYDGLMLYVQALNESLAESHGRPSSKSITERMWNRTYYGVTGL-VQIDKHGDRETDFALWDMTDTNSSVFQIVAV------YNGTQKQMRTLPGMAFHWPGGFIPPDMPFCGFKNDNPACIARTITMHQMVSIVVFFILVIIFTITVFIYRKLKLEKELAAQLWRISWEDMQMSNLEKVLRSAGSKLTLSLRG-SNYGSLLTADGNFQ-------------VFAKTAYFKGNIVAIKYVNRKRIELTRKVLFELKHMRDVQNDHLTRFIGACIDPPNVSIVTEYCPRGSL----------------------VLSGMAFLHNSVIVSHGNLKSSNCVVDNRFVLKITDYGLSSFRTES--DPE------DAHSYYARKLWMAPDLLRMSNPPACGTQKGDIYSFGIILQEVALRRGVF---YIEGDSLSPKEIVDRVALGEWPYLRPTVNTQAHSEELGQLMQRCWAEEPAERPEFSHIKVLLRKQNREVSRDILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSLSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIARMSLALLDAVKTFKIRHRPDQQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVSSASHDILQEFNCFQLELRGDVEMKGKGKMRTYWLLGE 1025          

Query: 1239 LTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALF-------LLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            L A  FH  D  +++  A++    ++     G  + K++++++F  VTGL V MD++GD E +F +   T+ E+G + +    +F            +      ++    P F  P   F + +  +    L+L V +  + + A          ++++R    E +L+  LW+V ++D+ I+        N  +  R   +  +  L    + S      + +I   + K   YKG I +IK++N K IELTRK   E++  +D+  E+LNR IG C+D PNICILT YC RGSL+D++  + I LD +F  SL+ D++KGM +LH+S I  HGNL++S CL+DSR++L+IT +GL S R  S        +  D   YY + LW +PE +++      G+QKGD+YSF II  EL    G +     P +  EI+  +          +RP++        +   +  CW +    RPDF  I+V+L    +G  SNI DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFT++SA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LH GEIA +SL LL+A+ SF IRHRP+  L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEALKIH S  T+ +L     + L  RG+IE+KGKG M TY+L  E
Sbjct:  331 LIAGGFH--DGVLLYSHALNESMDQSGLRPPGHVVTKKMWNRTFHGVTGL-VQMDENGDREIDFALWDMTDTESGVYEVFIYIHFYTVKKIIFNTTIILLPVCYTYAVCFPLFFSPLSTFISYSFLVLPFFLSLIVLLRFLFSFAFTGSVPLTPCVLSVRKVKLENELAAQLWRVYWEDIQIS--------NLDKALRRACSRLTLSLRGSNYGSLLTLEGNVQI---YAKTCYYKGNITAIKYVNKKRIELTRKVLFELKHMRDVQNEHLNRFIGACIDAPNICILTEYCPRGSLQDLMEIESITLDWMFRYSLINDIVKGMAFLHNSVIVSHGNLKSSNCLVDSRFVLKITDYGLASFRKES--------YLEDTHAYYARKLWTAPELMRDENRQPCGTQKGDVYSFGIILQELALLKGVFYLDSPPFSPKEIVEHV---AEGRWPYLRPLLCTQSHSEELGQLMQRCWSEDVNERPDFNQIKVMLHKNNRGYGSNILDNLLSRMEQYANNLEELVEERTQAYHEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTAMSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHTGEIARMSLALLEAVYSFRIRHRPDLQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHVSEATRAVLQEFNCFQLELRGDIEMKGKGRMRTYWLLGE 1047          

Query: 1221 TMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWIN-----EQKLSNLLWKVDFKDVTITD---VLPEYDNNKPRNYRNIDNHYSFLVAD-EFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            T+  S++   +   +D  M++ +A++     +    +   I + ++++++  VTGL V +DKHGD E +F +   T+  +  + I  V       N T  +    PG    W  G  P   P CGF N+N       + +   V ++V   L ++  I  +I      E++L+  LW++ ++D+ +++   VL    +    + R   N+ S L AD  F+              F K   +KG IV+IK++N K IELTRK   E++  +D+  ++L R IG C+DPPN+ I+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM +LH+S I  HGNL++S C++D+R++L+IT +GL S R  S  DP       DA  YY + LW +P+ L+   P + G+QKGDIYSF II  E+  + G     Y  G++      +      E   +RP ++       +   +  CW +    RP+F  I+V+L+   + +  +I DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTSLSA STPM+V                       ETIGDAYMVVSGLP+RN  LHA EIA +SL LL A+K+F IRHRP++ LKLRIGIHSGP  AGVVGLKMPRYCLFGDTVNT+SRME+ GE LKIH SS +  +L     + L  RG++E+KGKG M TY+L  E
Sbjct:  370 TVDDSLMNIISGGFYDGLMLYVQALNESLAESHGRPSSKSITERMWNRTYYGVTGL-VQIDKHGDRETDFALWDMTDTNSSVFQIVAV------YNGTQKQMRTLPGMAFHWPGGFIPPDMPFCGFKNDNPACIARTITMHQMVSIVVFFILVIIFTITVFIYRKLKLEKELAAQLWRISWEDMQMSNLEKVLRSAGSKLTLSLRG-SNYGSLLTADGNFQ-------------VFAKTAYFKGNIVAIKYVNRKRIELTRKVLFELKHMRDVQNDHLTRFIGACIDPPNVSIVTEYCPRGSLQDILENESITLDWMFKYSLINDIVKGMAFLHNSVIVSHGNLKSSNCVVDNRFVLKITDYGLSSFRTES--DPE------DAHSYYARKLWMAPDLLRMSNPPACGTQKGDIYSFGIILQEVALRRG---VFYIEGDSLSPKEIVDRVALGEWPYLRPTVNTQAHSEELGQLMQRCWAEEPAERPEFSHIKVLLRKQNREVSRDILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSLSAESTPMQV-----------------------ETIGDAYMVVSGLPVRNGKLHAREIARMSLALLDAVKTFKIRHRPDQQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVSSASHDILQEFNCFQLELRGDVEMKGKGKMRTYWLLGE 1063          

Query: 1182 ICNLKRFTKPQ-QITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENC------RLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKI-------RKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLK-DILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPG---NATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            +  LK+  K Q   T+  +++       +D  MM+  A++          +G  I K +++++++ VTG    +D++GD E +F++   T+M TG++N+      + + +    K    PG +I W  G  P   P CGF NE C       +E+ ++  S+ + +IVA + FL+   R    E++L+++LW++ ++++ ++ +       K R  R+  +  +        S R   SSC          + F K G Y+G +V+IK +N K IELTR+   E++  +D+  E+L R +G C+DPPNICI+T YC RGSL+ DIL N+ I LD +F  SL+ D++KGM++LH+S I  HG+L++S C++DSR++L+IT +GL S R  S  +        D    Y K LW +PE L+  +P  +G+QKGD+YS  II  E+  + G   + Y  G   +  EI++K+KN    +    RP  DE+     +   +  CW +    RPDF  I++++    K   +NI DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTSLSA STPM+VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  L+A EIA +SL LL A+K+F IRHR  + LKLRIGIH+GP  AGVVGLKMPR+CLFGDTVNTASRME+ GEALKIH S  TK +LD  G + L  RG++E+KGKG M TY+L  E
Sbjct:   91 VVKLKKRAKEQFNFTIEDTLMNLIAGSFYDAIMMYTAALNKTLSSGGGVHDGHAITKHMWNRTYRGVTG-EFTIDRNGDRETDFSLWDLTDMNTGEFNV------VLSYDGASSKLIEVPGLEIQWPGGSIPKDVPLCGFENEACISGGFSTMEVLMIVFSL-ILLIVAVSSFLIY--RKLKLEKELASMLWRLRWENIQVSSL------EKAR--RSAGSKLTL-------SMRG--SSCGSLLTTQGRNQMFAKTGYYRGNLVAIKPINKKKIELTREVLFELKHMRDVLNEHLTRFVGACIDPPNICIVTEYCPRGSLQQDILENESITLDWVFRYSLINDIVKGMLFLHNSVIGSHGSLKSSNCVVDSRFVLKITDYGLASFRSCSECE--------DMHSLYAKKLWTAPELLRLEHPPPQGTQKGDVYSLGIILQEIALRNG---TFYVEGMDLSPKEIVQKVKN---GQRPYFRPSTDESCHIEELGLLMQRCWAEDPAERPDFSQIKMLIHKFNKENSTNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAETLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSLSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLNAKEIARMSLALLDAVKTFKIRHRQEDKLKLRIGIHTGPVCAGVVGLKMPRFCLFGDTVNTASRMESNGEALKIHVSQTTKEVLDEFGCFRLELRGDVEMKGKGKMRTYWLLGE 820          

Query: 1920 KGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLK---GLRS----NIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPN 3449
            +G +V I F+N K IELTR+   E++  +D+  E+L R +G C+D PNICI+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM+YLH S I  HGNL++S C++DSR++L+IT +GL S+R  S  D S          Y+ K LW +PE L+      RG+QKGD+YSFAII  E+  ++GP+        A EI++++K     E   +RP +D       +   +  CW + S  RPDF  I+++L+       G  S     I DN+L  ME+YA NLE LVEERT    EEK K E LL ++LP SV EQLK G+TV  E +  VTIY SDIVGFT++SA STPM+VV  LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+ N   HA E+A ++L LL A++ F IRHRP + L LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRMEA GEA +IH SS TK +LD  GG+ +   G++++KGKG M TY+L  E+P 
Sbjct:    1 QGNLVEIPFINRKKIELTRQMLFELKHMRDVQNEHLTRFVGACIDVPNICIITEYCPRGSLQDILENESISLDWMFRYSLMHDIVKGMLYLHSSVIGSHGNLKSSNCVVDSRFVLKITDYGLSSVRAHSKADSS--------ANYFEKRLWTAPELLRLEEVAPRGTQKGDVYSFAIILQEIALRSGPFYLEANHLTAKEIVQRVK---LGEWPYLRPTVDPGGHSEELGHLMQRCWAEESTERPDFHQIKILLQKFSSQDDGPESPPAFTILDNLLSRMEQYANNLEELVEERTQAYLEEKGKAEALLYQILPHSVAEQLKRGETVPAEAFDSVTIYLSDIVGFTAMSAQSTPMQVVAFLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVHNGTRHAIEVARMALALLSAVRCFHIRHRPAQRLLLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMEAKGEAHRIHLSSTTKAILDEYGGFVVQLHGDVDIKGKGTMRTYWLLGENPT 506          

Query: 1245 AATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQS---FKSVTGLNVYMDKHGDAEGNFTVSSYTEMET--GQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCR--------LELNILA--LSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVL-PEYDNNKPRNYRNIDN-HYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFL--NHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAE---KYYYKLLWKSPEHLK-EPYPMSRGSQKGDIYSFAIIFHELTHQT--GPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            AA  H  D  +++  A+  + ++  +  +G  +++ I   +   F   +G  V +D +G+   ++ V    + +T  G+  I    YF     N  P++     +++ W  G PP   P+CGF+ E C+        L L ++   LS+ V   VA   +L+V  R    ++ +    WK++F+D+T+  ++   Y ++  +   N  N H+     D  E                 IG Y+G  V++KFL   H     + +F  +M   ++M  ENL    GVC++ PN+CI+T YC +GSLKD+L   D  LD +F  S   D++ GMI+LH S I  HGNL+ S CL+DSR  +++TGFG+   RY           +LD      ++ +L W +PE L+ E  P++ G+ KGD++SFAI+  E+ +    GP+  I+      +II ++++  +  +  +RP++ E   P  ++  + +CWD+ ++RRPDF  +  +L+        NI DNM+  +EKYA +LE +V++RT QL  EKKK +RLL  +LP  V +QLK G+TV PE Y  VTI+F DIVGFT++SA STP+EV+ +LNDLY L D II EYDVYKVETIGDAYMV SGLP+RN   H  EIA++SLH L +I +F IRH P E LKLRIGI+SGP VAGVVG  MPRYCLFGDTVN ASRME+TG  L IH S  T  LL  +GGY L++RG I +KGKG+ +TY+L+ +
Sbjct:    1 AAYLH--DAGILYAMAVRELLRQGGNPRDGRAVIRTIRGSNKIKFYGASG-QVSIDVNGERFLDYAVFDLQKKQTATGEMRIASKRYFTFQTINFTPEY-----QKMGWPDGRPPSDMPECGFTGELCQEAPISEPDLALVLVGSILSLIVIGTVAFLTYLVVQSRSL--QESMDTTWWKINFEDITLVPLVNGSYRSSSKQVSGNQSNVHHDVHGTDRVE---------------IPIGIYQGNQVALKFLERTHPPDLKSNRFALKM---REMLHENLVIFFGVCVELPNVCIVTQYCRKGSLKDVLKTSDFELDWMFKTSFAHDIVNGMIFLHKSPIKSHGNLKPSTCLLDSRLQIKLTGFGIWEFRYGKKG------KTLDINNLGSFFIELYWTAPELLRMEDLPVN-GTPKGDVFSFAILMREVIYHEDEGPYVGIHL--EPKDIIDQVRDGIA--VPPLRPLLTERCEPR-IQALIRQCWDESADRRPDFSSVSRMLRLASPEGDMNILDNMVSKLEKYANHLEEVVDDRTAQLESEKKKTDRLLSSLLPGIVVDQLKAGKTVQPEQYELVTIFFCDIVGFTAMSAISTPLEVINLLNDLYNLLDDIIKEYDVYKVETIGDAYMVASGLPVRNGVRHVEEIATMSLHFLSSIMNFRIRHLPQEQLKLRIGINSGPVVAGVVGNTMPRYCLFGDTVNVASRMESTGFPLHIHVSEATTNLLKQIGGYFLVERGTINLKGKGNQLTYWLKGK 717          

Query: 1563 GHPPFHEPKCGFSNENCRLELN-----ILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNY-RNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFF--KDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYK-LLWKSPEHLK-EPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILK-PLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            G PP   P+CGF+ E C+   +     +  LS+ V   VA   +L+V  R    ++ +    WK++F+D+T+     E  +     Y  ++ NH       E ES + P  +   R +  ++   +  +       H  +  T +    +  +  ++M  ENL    GVC++ PN+CI+T YC +GSLKD+L   D  LD +F  S   D++ GMI+LH S I  HGNL+ S CL+DSR  +++TGFG+   RY       +     DA     K L W +PE L+ E  P++ G+ KGD++SFAI+  E T +  P  +        +II ++++  +  +  +RP++ E   P  ++  + +CWD+ ++RRPDF  +  +L+    +GL  NI DNM+  +EKYA +LE +V++RT QL  EKKK +RLL  +LP  V +QLK G+TV PE Y  VTI+F DIVGFT++SA STP+EV+ +LNDLY L D II EYDVYKVETIGDAYMV SGLP+RN   H  EIA++SLH L +I +F IRH P E LKLRIGI+SGP VAGVVG  MPRYCLFGDTVN ASRME+TG  L IH S  T  LL  +GGY L++RG I +KGKG+ +TY+L+ +
Sbjct:   10 GRPPSDMPECGFTGELCQCNWSCFTGAVTILSLIVIGTVAFLTYLVVQSRSL--QESMDTTWWKINFEDITLVSTSKEGMHTTVYLYVLSMLNHIV-----ESESLQVPLVNGSYRSSSKQVSGNQSNV-------HHDVHGTDRVEIPIGIYQMREMLHENLVIFFGVCVELPNVCIVTQYCRKGSLKDVLKTSDFELDWMFKTSFAHDIVNGMIFLHKSPIKSHGNLKPSTCLLDSRLQIKLTGFGIWEFRYGKKGKTLDINKQEDAWALSSKELYWTAPELLRMEDLPVN-GTPKGDVFSFAILMRESTPREWPTATRANRVPFPDIIDQVRDGIA--VPPLRPLLTERCEPR-IQALIRQCWDESADRRPDFSSVSRMLRLASPEGLHMNILDNMVSKLEKYANHLEEVVDDRTAQLESEKKKTDRLLSSLLPGIVVDQLKAGKTVQPEQYELVTIFFCDIVGFTAMSAISTPLEVINLLNDLYNLLDDIIKEYDVYKVETIGDAYMVASGLPVRNGVRHVEEIATMSLHFLSSIMNFRIRHLPQEQLKLRIGINSGPVVAGVVGNTMPRYCLFGDTVNVASRMESTGFPLHIHVSEATTNLLKQIGGYFLVERGTINLKGKGNQLTYWLKGK 628          

Query:  648 RTNPPISKAVKSIIALMHKFSWTKFALVSSSSRQWKLAS-DEL-KQVAHXXXXXXXXXXXXXXDNASKSM--KEIIDSTSKEIRIYVIMTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNI--KRVNKKMLNVNDNFPTAAMRSMLFLSTA---TPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQS---FKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYF--IQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCR------------LELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSN-----LLWKVDFKDVTITDVLPEYDNNKPRNYRNI-----DNHYSFLVADEFESRRKPRSSCKIR-KTFTKIGSYKGMIVSIKFLNH-KSIELTRK-FRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLK-EPYPMSRGSQKGDIYSFAIIFHELTHQT--GPW-GSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFL 3431
            R   P+ +  + + A M  F WT+ A++  +++    A+ DEL   V  +    +     I  D + K +  + ++D ++K  RI +++    E  + +    SL +A +G+++ + V  +F + F   +K++  +R++ + L        A    MLF   A   +   + L+ +   +    F    +  +   P           AA  H  D  +++  A+  + +   +  +G  I++ I   +   F  V+G  V +D +G+   ++ V +  + +       PV  F   Q   +  P++     +++ W  G PP   P CGF  E C+            L+   LAL +   +     +  +V I Y I ++ L       + WK++ +++ +         +KP  +  +           L+      + K     ++R K FT +G Y+G  V++KFL   +  +L  K   +E+Q  +++  ENL    GVC++ PNICI+T YC +GSLKD+L   D  LD +F  S  +D++ GMI+LH S I  HGNL+ S CL+DSR  +++TGFG+   R+       +  +   AE     L W SPE L+ E +P++ G+ KGD++SF ++  E+ +    GP+ G    P    + +R+ K         +RP++ E   P  ++  +  CWD+  +RRPDF  I  +L+        +I DNM+  +EKYA +LE +VE+RT QL  EKKK +RLL  +LP  V EQLK G+TV PEH+  VTI+F DIVGFT++SA S+P+EV+ +LNDLY L D II EYDVYKVETIGDAYMV SGLP+RN   H  EI+ +SLH L +I +F IRH P E LK+RIG++SG  VAGVVG  MPRYCLFGDTVN ASRME+TG  L+IH S  T  LL ++GGY L++RG I++KGKG  +TY+L
Sbjct:  133 RIMSPLQRMGQMLEATMRHFGWTRAAMLGGTAQNSTWANIDELWASVERELARSVTITARIKYDTSDKVLHRQNLLDISTKA-RIVILICGSEEAREVLLEAQSLGLA-TGKFIFL-VVQQFEDSF---WKSVAAERLDTQTLQ-------ALEPVMLFTIKAYGSSDYELFLQEVRRRLLGPPFYSNLSSDKEVSPY----------AAYLH--DAAILYAMAVRELLRHGGNPRDGRAIVRTIKGSTKVKFYGVSG-QVNIDVNGERFLDYAVFNL-QKKGNSSQFLPVMVFDTFQGSISFTPEY-----QKMVWPEGGPPNDMPICGFLGELCQEIPYSGVVLKPALDEPDLALVLVGTISSVVIVGSVVYILYLIVQRHLLQGGKDFMWWKINIEEIVMVS------TSKPTKHTTVVSCIEPRECGILLTANSGGKWK----LQVREKMFTPLGIYQGNQVALKFLQRTRPPDLKSKTLLKELQMLRELRHENLVVFFGVCVEMPNICIVTQYCRKGSLKDVLKTSDFELDLMFKTSFAYDIVNGMIFLHKSPIKSHGNLKPSTCLLDSRLQIKLTGFGIWEFRHGKKGKIMDVNNQDIAE-----LFWTSPELLRMEIFPVN-GTPKGDVFSFGVLMREMIYHEDEGPYVGVDMEPKEIIDQVREGKCS-----PPLRPLLTERCEPR-IQALIQRCWDESPDRRPDFHSIARMLRSASPEGHRSILDNMVSKLEKYANHLEEVVEDRTAQLESEKKKTDRLLSSLLPSVVVEQLKAGKTVQPEHFEQVTIFFCDIVGFTAMSAISSPLEVITLLNDLYNLLDDIIKEYDVYKVETIGDAYMVASGLPVRNGVRHVEEISIMSLHFLSSIINFRIRHLPKEQLKIRIGVNSGSVVAGVVGNTMPRYCLFGDTVNVASRMESTGYPLRIHVSESTASLLKSIGGYELVERGAIQLKGKGSQLTYWL 1049          

Query: 1893 KTFTKIGSYKGMIVSIKFLN-HKSIELTRKF---RQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFG---------LQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKG-----DIYSFAIIFHELTHQTGPWGSI 2495
            + ++ I    G I+++K +  H +  + + F   ++EM   + +N  N+ +  GV +    + I   YC  GSL  +L +  I  DE+      F+L++G+ YLH S +  H +++    L+D   I++   FG          +++R A+ +D      SL+        +  +P ++  P  +S  + KG     D+++   +  E+     PW ++
Sbjct: 1047 QVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRI-EDEMVTQVYTFELLEGLAYLHQSGV-VHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNE-------MMGTPMYMA-PETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNL 1255          

Query: 1965 ELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPW 2486
            ++    + EM   K+++ EN+    G   +  N+ I   Y   GS+  +L+N   F +E  + +    ++ G+ YLH   I  H +++ +  LID +  ++IT FG+ S + +      N   SL        + W SPE +K+    +  + K DI+S   +  E+     P+
Sbjct:  496 KMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPF-EESLITNFTRQILIGVAYLHKKNI-IHRDIKGANILIDIKGCVKITDFGI-SKKLSPLNKKQNKRASLQGS-----VFWMSPEVVKQ----TATTAKADIWSTGCVVIEMFTGKHPF 657          

Query: 1899 FTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQK-GDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRP 2654
            +  I  +   +V+IK + +++ E       E+   K++N  N+ +  G       + IL  YC+ GSL+ ++S     L E    + +   + G+ YLH   +  H +++ +  L+ +   +++  FG+ +I  +S            A      L W +PE L      +RG+    DI+S      E+  +  P+ ++        I   ++N+T    SS    +         KD L++C+     +RP
Sbjct:   40 YKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGV-IHRDIKAANILLSADNTVKLADFGVSTIVNSS------------ALTLAGTLNWMAPEILG-----NRGASTLSDIWSLGATVVEMLTKNPPYHNL----TDANIYYAVENDTYYPPSSFSEPL---------KDFLSKCFVKNMYKRP 261          

Query: 1893 KTFTKIGSYKGMIVSIKFLNHKSIELTRKF----RQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFG 2282
            + ++ +    G I+++K +N +  +  +K     ++EM   + +N  N+    GV +    + I   YC  GSL  +L +  I  DE+        L++G+ YLH+S I  H +++    L+D   +++   FG
Sbjct: 1279 RVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRI-EDEMVTQVYTLQLLEGLAYLHESGI-VHRDVKPENILLDFNGVIKYVDFG 1410          

Query: 1890 RKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKY--YYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRP----IIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESED 3443
            R+ FT +G YK  +V+IK +N + IELTR+ + EM+  + +  ENL    G C++PPNICIL  YC +GSL+DIL N+DI LD +FV SLL D++KGM YLH ++I  HG L++  C++D RW+L+IT +GL   +       SN   S +  +Y  YY+ LW +PE L+   P  RG+QKGD+YSF II  EL  ++GP+   Y     ++II K+   T  E    RP    I+ E      + D    CW++  + RPDF+ IR  ++ L  G +SNI DNM+ ++EKYA NLE LVEERT QL++EK+K E LL RMLP SV + L  G+ V  E++  V+I+FSDIVGFTSLS+ STP++VV +LNDLYTLFD II  YDVYKVETIGDAYMVVSGLP+RN   HAGEIA+++LH+L+ I SF IRHRPN+ LKLRIGIHSG CVAGVVG KMPRYCLFGDTVNTASRME+ GEALKIH S  TK +LD LGGY + KRG + +KGKG  ITY+L   D
Sbjct:    5 RQIFTTVGIYKSNMVAIKRINKRQIELTREIKYEMKLMRTVRHENLVTFTGACVEPPNICILLQYCPKGSLQDILENEDIKLDSMFVNSLLTDIVKGMAYLHSTEIRSHGRLKSPNCVVDGRWVLKITDYGLNKFK-------SNQDISEEEGEYAMYYRKLWTAPELLRAADPRPRGTQKGDVYSFGIIVQELLTRSGPFDLSYYTNEPSDIIEKV---TRVESPPFRPKLSTIVLEGPTVAGIVDLAKWCWEENPDHRPDFEEIRKTVRKLPMGKQSNIMDNMVNLLEKYANNLESLVEERTSQLADEKRKTENLLNRMLPPSVAKDLVHGKQVTAENFDEVSIFFSDIVGFTSLSSESTPLQVVDLLNDLYTLFDEIINNYDVYKVETIGDAYMVVSGLPIRNGHQHAGEIATMALHMLREIDSFKIRHRPNDKLKLRIGIHSGSCVAGVVGKKMPRYCLFGDTVNTASRMESNGEALKIHISPSTKRILDELGGYHIQKRGKVFLKGKGTWITYWLVGSD 518          

Query: 1926 MIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDP--SNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIY-RPGNATEIIRKLKNETSNELSSMRPIIDE-TQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLL--KGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIK-SFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLES 3437
            M+V++  L  ++I+++R+   EM+  +D+  +NLN+ IG C+ PPN+CI+  YCSRGSL+DIL N D+ LD +F+ASLL D++KGM YLH+S I  HGNL++S CL+DSRW+L+IT +GL  +R  S K    +NW            LLW +PE L+ P    +G+ KGD+YSF+II  E   + GP+ + Y  P    E +RK      +E    RPI+         ++D + +CW +  + RPDF  I+  ++ ++   G++ NIFDNM+ +ME YA NLE LV +RT QL +EK+K + LL  +LP+ V EQLK G+ V  E ++ VTIYFSDIVGFTSLSA STPM+VV  LNDLYT+FD II EYDVYKVETIGDAYMV SGLP+RN   HAGEIA ++LHL+ A+  +F++RH+P   L+LR+G H+GP VAGVVG  M RYCLFGDTVNTASRME+ GE L+IH S +TK +LD LG + +  RG + +KGKG + T++L S
Sbjct:    1 MLVTVAALPKRTIDISRQLLLEMKQMRDIRHDNLNQFIGACVGPPNVCIVMQYCSRGSLQDILENDDVKLDLVFIASLLSDIVKGMEYLHNSDIRSHGNLKSSNCLVDSRWVLKITDYGLPLLRSRSKKSTIETNW----------RDLLWVAPEILRIPSRPPKGTHKGDVYSFSIILQEFHTRDGPYSANYMEPKAIIEKVRK------SEFPPYRPIVANLIDGAEELRDLMKQCWAEDPDLRPDFTEIKKTVRRIVDKSGMKKNIFDNMVNMMEIYADNLENLVAQRTDQLVDEKRKTDALLESILPRPVAEQLKKGKAVEAESFNEVTIYFSDIVGFTSLSAESTPMQVVTFLNDLYTIFDDIIQEYDVYKVETIGDAYMVASGLPIRNGRRHAGEIAKMALHLVDAVSHNFIVRHKPEYKLQLRVGCHTGPVVAGVVGNTMARYCLFGDTVNTASRMESNGEPLRIHISQQTKDVLDELGTFVVKSRGKVHLKGKGTVETFWLVS 495          

Query: 1920 KGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLK------EPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSI-YRPGNATEIIR-----KLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATG 3305
            K  +V++K L   S+ LTR    EM+  +D+   NL   IGVC  PPNICI++ YC RGSL++IL+N +I LD  F  S   D+  GM  +H S I+ HG+LR+SKCLIDSRW+ ++  FGL  ++     DP    H+      Y +L W++PE L+      +P P    +Q GD+YSF II +EL  +  P+ +  + P    E IR       + ET  E+ +             V   +T+CW+D  + RP F  I+  L+ LLKG +S+I DNML +ME Y + LE +V+ERT QL++EK K + LL +MLP+ + E LK G+ VI E YS VTI+FSDIVGFT L+A+STP++VV +LNDLYT FD+II ++DVYKVETIGDAYMVVSGLP+RN   HAGEIA+++L+LL ++ +F  RH PN  + LRIGIH+G CVAGVVGLKMPRYCLFGDTVN ASRME+TG
Sbjct:   66 KSYLVALKMLRKDSLTLTRDMLIEMKQVRDVQHTNLLHYIGVCTTPPNICIVSQYCHRGSLQEILANDEISLDWFFRESFANDIAMGMHVIHTSSIHVHGDLRSSKCLIDSRWVCKVADFGLNLLKANQRPDPEIGVHA-----QYSRLFWRAPELLQNEKSTNKPVP----TQMGDVYSFGIILNELLTREEPYATTEFAPIEVIERIRCHLNPPFRPETPFEIRNRS-----------VTKLMTQCWNDDPQARPTFSDIKRQLR-LLKGGKSSIVDNMLRLMENYTEQLETIVDERTRQLADEKAKTDELLYKMLPRYIAESLKRGEPVIAESYSSVTIFFSDIVGFTELAAASTPLQVVDLLNDLYTCFDTIIDKHDVYKVETIGDAYMVVSGLPVRNGHRHAGEIATMALNLLSSMGNFRARHLPNRPIHLRIGIHTGSCVAGVVGLKMPRYCLFGDTVNYASRMESTG 518          

Query: 2010 MNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYY----KLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLK-----------LRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESED 3443
            ++  N+N  IGVC+  PNICI++  C RGSL D+L N DI LD  F  S   D+  GM  LH S++++HGNL +S CL+D  W+ +I  +GLQ  R++         H+ + E+       K LW +PEH++     S GSQ GD+YSF +I  E+  +  P+ ++      T I+R++    S E   +RP ++       +   + +CW +    RP F+ I+  ++ +  G    + D+ML  M+ Y+ NLEVLVEERT QL  EK K ++LL  MLP+ V +QLK G++V  E +  VT++FSDIVGFT LS+SSTP++VV  LNDLYT FD+II  YDVYKVETIGDAYMVVSGLP +N D HAGEIA+++LHLL  I++F IRH P+  L            L   I SGP VAGVVG+K PRY +FGDTVN ASRME+ G   +IH S+E +  L  LGGY + +RG IE+KGKG +ITYFL  +D
Sbjct:    5 LSHVNINPYIGVCITAPNICIVSEACGRGSLADVLINDDIKLDWTFKMSFATDIAAGMEALHASEVSFHGNLTSSNCLVDRMWVCKIADYGLQ--RFSK--------HTYEPEEQLTGQTGKSLWMAPEHMRNAS--STGSQPGDVYSFGVILSEIVTRCEPFETLRA---TTSILRRI---MSTEFPPLRPTLNADDCDPTITKFIKQCWSEEPSARPTFRDIKKSMRKINGGRSLRLVDSMLGKMDIYSNNLEVLVEERTRQLEAEKAKTDQLLYEMLPRPVADQLKSGKSVEAELFDQVTVFFSDIVGFTKLSSSSTPIQVVTFLNDLYTYFDNIIPNYDVYKVETIGDAYMVVSGLPEKNRDRHAGEIATMALHLLCDIRTFKIRHVPDTRLVSSYSLLLIITCLFYLIFSGPAVAGVVGIKKPRYDVFGDTVNVASRMESNGVPNRIHISAECRKALLNLGGYHMERRGEIELKGKGKVITYFLNGKD 479          

Query: 1992 MQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRY-ASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRG-------SQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESED------PNVR 3455
            M+  +D++  NLNR +GVC++ PNIC+++ +C+RG+L+D+L N  I LD +F  S   D+  GM  +H+S I  HGNL++S CLIDSRW  +IT +GL  +R   +PKD   +         Y  L W +PE L    P++ G       +Q GD+YS+ I+ +E+  +  P+ +     ++ ++I  ++               E +  + +     +CWD+ +++RP F  I+  LK    G+ +     M     +Y  N   LV  R          ++RLL+  L + + ++LK G +V  E +  VTI+FSDIVGFTS++A STP++VV +LN LYT FD ++ E+DVYKVETIGDAYMVVSGLP+RN + HAGE+AS++L+LL  ++ F I H P+  ++LRIGIHSG CVAGVVGLKMPRYCLFGDTVN ASRME++G AL+IH S E K +LD LGGY L +RG + +KGKG ++TYFL  +D      P+VR
Sbjct:    1 MKMVRDLHHANLNRYLGVCVESPNICMVSRFCNRGTLQDLLGNDSIKLDWMFRQSFANDIATGMEAIHNSPIQAHGNLKSSNCLIDSRWACKITDYGLDLLRANQTPKDIGEFA-------VYKNLFWTAPELL----PLADGFKDRKNKTQAGDVYSYGIVLYEIITRDEPYSTNTDTLSSKDVIELVRKRQEPAFRPQFSKFMEEKSGHKMVQVTQDCWDNDAQKRPTFSAIKKKLKA--NGMGNGKISGMF---SRYYNNFSKLVISRMGVC----MALKRLLV--LSRPIADELKKGNSVSAESFQSVTIFFSDIVGFTSVAAQSTPLQVVDLLNQLYTRFDKVVDEHDVYKVETIGDAYMVVSGLPVRNGERHAGEVASMALNLLSEVRDFQIPHIPSRKVQLRIGIHSGSCVAGVVGLKMPRYCLFGDTVNYASRMESSGLALRIHVSPECKEVLDRLGGYHLDERGPVTMKGKGTIVTYFLTGKDGFDKPLPDVR 480          

Query: 1239 LTAATFHTFDLTMMFFKAIDNIFQRNDSELN------GTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAI-----RYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKL-KNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESED 3443
            L A  F  +D  M++ +A++    +    L       G  + + +++++F+ V G  V MDK GD E +F +   T++ +G++ +  V       N+++ +  +  G    W  G PP   P+CGF N+N     + + +   V +++     +++ I     R    E +L+  LW+V + D+ ++        N  +  R   +  +  +    + S      + +I   +TK G YKG +V+IK++N K IELTR    E++  +D++ E+L R IG C+DPPN+CI+T YC RGSL+D++ ++ + LD +F  SL+ D++KGM +LH+S I  HGNL++S C++DSR++L+IT +GLQS+R +S  D        D   YY + LW +PE L+   P   G+QKGD+YSF II  EL    G    ++     T I +++ +      +  +RP +        +   +  CW +    RPDF  I+++L+   +G  SNI DN+L  ME+YA NLE LVEERT   +EEK+K E LL ++LP SV +QLK G+TV  E +  VTIYFSDIVGFT+LSA STP++VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LH  E+A ++L LL A+KSF IRHRP++ L+LRIG+HSGP  AGVVGLKMPRYCLFGDTVNTASRME+TGEALKIH S  T+ +L     + L  RG IEVKGKG M TY+L+ ED
Sbjct:  336 LIAGGF--YDGVMLYSRALNETLSKRKPGLRPVQRPKGDMVTQRMWNRTFQGVMG-TVEMDKFGDREIDFALWDMTDINSGKFEVVCV------YNSSIKELVLQKGLNFQWPGGSPPLEVPECGFKNDNPACLTSTVTMHQMVAMVICFVFVIIITITIFIYRKLKLENELAAQLWRVSWVDIQMS--------NLDKVLRRACSRLTISMKGSNYGSLMTMEGNLQI---YTKTGYYKGNLVAIKYINKKRIELTRNVLFELKHMRDVHNEHLTRFIGACVDPPNMCIITEYCPRGSLQDLMESESMTLDWMFRYSLINDIVKGMTFLHNSVIFSHGNLKSSNCVVDSRFVLKITDYGLQSLRTSSCPD--------DTHAYYARKLWTAPELLRTEDPPLCGTQKGDVYSFGIILQELALLKG----VFYIDTHTLIPKEIIQGVIRGGVPLLRPSLCFHSHSEELGVLMQRCWCEEPGERPDFNTIKILLRKQHRGYGSNILDNLLSRMEQYANNLEELVEERTQAYNEEKRKAEALLYQILPHSVADQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREVARMALALLDAVKSFKIRHRPSQQLRLRIGVHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESTGEALKIHVSEATRQVLQEFNTFQLQPRGEIEVKGKGHMRTYWLQGED 1051          

Query: 1263 FDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNEN--CRLELNILALSVCVCVIVAGALFLLVAI---RYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESE 3440
            +D  M++  A++       +   G  I  ++++++F  VTGL +++D  GD E +F +    +  +  + I  V       N+   + T  PG  + W+ G  P   PKCGF N+N  C  +   +   V + +     + L +AI   R    E++L   LW++ + D+ ++        N  +  R+       L    + S      + ++   F K G YKG IV+IK+ N K IEL RK   E++  +D+  E+L R IG C+DPPNICI+T YC RGSL+DIL N  I L+ +F  SL+ D++KGM++LH+S I  HG L++S C++D+R++L+IT +GL + R  S           D+  YY + LW +PE L+   P  +G+QKGD+YSF+II  E+  + G +     P +  EI+ ++      +   +RP ID       +   +  CW +    RPDF  IR++L+   K  R+NI DN+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  V+IYFSDIVGFT+LSA STPMEVV +LNDLYT FD++I  +DVYKVETIGDAYMVVSGLP+RN  LH  EIA ++L LL  +++F IRHRP + LKLRIGIHSGP  AGVVGLKMPRYCLFGDTVNT+SRME++GEALKIH S+ T+ +L     + L  RG+I++KGKG M TY+L  E
Sbjct:  357 YDGLMLYAHALNETALVPGARPPGKLISGKMWNRTFHGVTGL-LHLDVSGDRETDFALWDLVDTNSSSFQIVVV------YNSFEEQVTPVPGTSVRWLGGARPLDVPKCGFKNDNPACLTKTITIHQMVSITLFFIFTMTLTIAIFICRKMKLEKELVAQLWRISWDDIQMS--------NLDKVLRSGSRITLSLRGSNYGSLMTANGNLQV---FAKTGYYKGNIVAIKYTNKKRIELNRKVLFELKHMRDVQNEHLTRFIGACVDPPNICIITEYCPRGSLQDILENDSITLEWMFKFSLINDIVKGMVFLHNSVIFSHGKLKSSNCVVDNRFVLKITDYGLSTFRQESDVGS-------DSHSYYAQKLWMAPELLRMENPPPQGTQKGDVYSFSIILQEVALRRGAFYLDGDPLSPKEIVDRV---ILGDWPCLRPSIDPQSHSPELGQLMQRCWAEEPTERPDFNHIRLLLRKHNKESRTNILDNLLSRMEQYANNLEELVEERTQAYHEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVSIYFSDIVGFTALSAESTPMEVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREIARMALALLDTVRTFRIRHRPEQQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESSGEALKIHVSAATRDVLIEFNSFQLELRGDIDIKGKGKMTTYWLLGE 1059          

Query: 1245 AATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLE-----LNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNV 3452
            A +F  +D  +++  A+D       ++ NG  I +   ++SF  VTGL V +DK      +  + + T  ETG++ +  V+Y+    N +  +       +I W S  PP   P C FS ++         L I+A+   + +I+ G    L+  +  + E++L+ +LW+V ++D+             P  Y          ++    S     ++    + F K G +KG +V+IK +N K IELTR+   E++  +D+   +L R IG C+DPPNICI+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM +LH+S    HGNL++S C++DSR++L+IT +GL S R +   D        D+   Y K LW +PE L   +   +G+QKGD+YSF II  E+  + GP+       +  EI++K++N    +    RP  D       +   +  CW +    RPDF  I++ +  L K   ++I +N+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTS+SA STP++VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LHA EIAS+SL LL+ +K+F IRHRPN+ L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEALKIH SS TK +LD    + L  RG++E+KGKG M TY+L  E  +V
Sbjct:  343 AGSF--YDGFVLYAMALDETLAEGGAQNNGINITRRTQNRSFWGVTGL-VSIDKRNARNIDVDLWAMTNQETGEYGV--VSYY----NGSTKEIVWSQTEKIHWPSCGPPLDNPPCVFSTDDPSCNDGLPVLGIVAVGSGLALIIFGISSFLIYRKLKL-EKELAGMLWRVQWEDLQF---------ESPNKYHKRAGS-RLTLSQRGSSYGSLITAQGKYQLFAKTGYFKGNLVAIKHVNKKRIELTRQVLMELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENESINLDWMFRYSLINDIVKGMNFLHNSYFGCHGNLKSSNCVVDSRFVLKITDYGLASFRSSCEND--------DSHALYAKKLWTAPELLIYDHHPPQGTQKGDVYSFGIILQEIALRNGPFYVESMDLSPKEIVQKVRN---GQRPYFRPTTDSRFHSEELTILMEGCWAEDPAERPDFGHIKIYMAKLNKEGSTSILNNLLSRMEQYANNLENLVEERTQAYLEEKRKAENLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSMSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIASMSLALLEQVKTFKIRHRPNDQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHVSSATKEVLDEFCYFNLELRGDVEMKGKGKMRTYWLLGEKTDV 1052          

Query: 1245 AATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLE-----LNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNV 3452
            A +F  +D  +++  A+D       ++ NG  I +   ++SF  VTGL V +DK      +  + + T  ETG++ +  V+Y+    N +  +       +I W S  PP   P C FS ++         L I+A+   + +I+ G    L+  +  + E++L+ +LW+V ++D+             P  Y          ++    S     ++    + F K G +KG +V+IK +N K IELTR+   E++  +D+   +L R IG C+DPPNICI+T YC RGSL+DIL N+ I LD +F  SL+ D++KGM +LH+S    HGNL++S C++DSR++L+IT +GL S R +   D        D+   Y K LW +PE L   +   +G+QKGD+YSF II  E+  + GP+       +  EI++K++N    +    RP  D       +   +  CW +    RPDF  I++ +  L K   ++I +N+L  ME+YA NLE LVEERT    EEK+K E LL ++LP SV EQLK G+TV  E +  VTIYFSDIVGFTS+SA STP++VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LHA EIAS+SL LL+ +K+F IRHRPN+ L+LRIGIH+GP  AGVVGLKMPRYCLFGDTVNTASRME+ GEALKIH SS TK +LD    + L  RG++E+KGKG M TY+L  E  +V
Sbjct:  291 AGSF--YDGFVLYAMALDETLAEGGAQNNGINITRRTQNRSFWGVTGL-VSIDKRNARNIDVDLWAMTNQETGEYGV--VSYY----NGSTKEIVWSQTEKIHWPSCGPPLDNPPCVFSTDDPSCNDGLPVLGIVAVGSGLALIIFGISSFLIYRKLKL-EKELAGMLWRVQWEDLQF---------ESPNKYHKRAGS-RLTLSQRGSSYGSLITAQGKYQLFAKTGYFKGNLVAIKHVNKKRIELTRQVLMELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENESINLDWMFRYSLINDIVKGMNFLHNSYFGCHGNLKSSNCVVDSRFVLKITDYGLASFRSSCEND--------DSHALYAKKLWTAPELLIYDHHPPQGTQKGDVYSFGIILQEIALRNGPFYVESMDLSPKEIVQKVRN---GQRPYFRPTTDSRFHSEELTILMEGCWAEDPAERPDFGHIKIYMAKLNKEGSTSILNNLLSRMEQYANNLENLVEERTQAYLEEKRKAENLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSMSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIASMSLALLEQVKTFKIRHRPNDQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHVSSATKEVLDEFCYFNLELRGDVEMKGKGKMRTYWLLGEKTDV 1000          

Query: 1392 VYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAI-----RYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSF-LVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKL-KNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESED 3443
            V MDK GD E +F +   T++ +G++ +             LPK     G    W  G PP   P+CGF N+N     + + +   V +++     +++ I     R    E +L+  LW+V + D+ ++        N  +  R   +  +  +    + S      + +I   +TK G YKG +V+IK++N K IELTR    E++  +D++ E+L R IG C+DPPN+CI+T YC RGSL+D++ ++ + LD +F  SL+ D++KGM +LH+S I  HGNL++S C++DSR++L+IT +GLQS+R +S  D        D   YY + LW +PE L+   P   G+QKGD+YSF II  EL    G    ++     T I +++ +      +  +RP +        +   +  CW +    RPDF  I+++L+   +G  SNI DN+L  ME+YA NLE LVEERT   +EEK+K E LL ++LP SV +QLK G+TV  E +  VTIYFSDIVGFT+LSA STP++VV +LNDLYT FD+II  +DVYKVETIGDAYMVVSGLP+RN  LH  E+A ++L LL A+KSF IRHRP++ L+LRIG+HSGP  AGVVGLKMPRYCLFGDTVNTASRME+TGEALKIH S  T+ +L     + L  RG IEVKGKG M TY+L+ ED
Sbjct:  341 VEMDKFGDREIDFALWDMTDINSGKFEV-----------KHLPK-----GLNFQWPGGSPPLEVPECGFKNDNPACLTSTVTMHQMVAMVICFVFVIIITITIFIYRKLKLENELAAQLWRVSWVDIQMS--------NLDKVLRRACSRLTISMKGSNYGSLMTMEGNLQI---YTKTGYYKGNLVAIKYINKKRIELTRNVLFELKHMRDVHNEHLTRFIGACVDPPNMCIITEYCPRGSLQDLMESESMTLDWMFRYSLINDIVKGMTFLHNSVIFSHGNLKSSNCVVDSRFVLKITDYGLQSLRTSSCPD--------DTHAYYARKLWTAPELLRTEDPPLCGTQKGDVYSFGIILQELALLKG----VFYIDTHTLIPKEIIQGVIRGGVPLLRPSLCFHSHSEELGVLMQRCWCEEPGERPDFNTIKILLRKQHRGYGSNILDNLLSRMEQYANNLEELVEERTQAYNEEKRKAEALLYQILPHSVADQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREVARMALALLDAVKSFKIRHRPSQQLRLRIGVHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESTGEALKIHVSEATRQVLQEFNTFQLQPRGEIEVKGKGHMRTYWLQGED 992          

Query:  900 MTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKERKISGESQDTPIEMKLKYNLSEENLDADEFLRKISLSSHNSMNTNCNVNVLPTVDFKESFKSTRFSTHRATLHEYSSPWKNSSFSSQSEHINLYKKPSEVTNFPKNGSLKLMKESLNHVIGDIDATKSLLHES 3887
            MTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVI+AGALFLL AIRYWINEQKLSNLLWKVDFKDV ITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKERKISGESQDTPIEMKLKYNLSEENLDADEFLRKISLSSHNSMNTNCNVNVLPTVDFKESFKSTRFSTHRATLHEYSSPWKNSSFSSQSEHINLYKKPSEVTNFPKNGSLKLMKESLNHVIGDIDATKSLLHES
Sbjct:    1 MTSVMEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVILAGALFLLAAIRYWINEQKLSNLLWKVDFKDVMITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKERKISGESQDTPIEMKLKYNLSEENLDADEFLRKISLSSHNSMNTNCNVNVLPTVDFKESFKSTRFSTHRATLHEYSSPWKNSSFSSQSEHINLYKKPSEVTNFPKNGSLKLMKESLNHVIGDIDATKSLLHES 996          

Query:  912 MEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKERKISGESQDTPIEMKLKYNLSEENLDADEFLRKISLSSHNSMNTNCNVNVLPTVDFKESFKSTRFSTHRATLHEYSSPWKNSSFSSQSEHINLYKKPSEVTNFPKNGSLKLMKESLNHVIGDIDATKSLLHES 3887
            MEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVI+AGALFLL AIRYWINEQKLSNLLWKVDFKDV ITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKERKISGESQDTPIEMKLKYNLSEENLDADEFLRKISLSSHNSMNTNCNVNVLPTVDFKESFKSTRFSTHRATLHEYSSPWKNSSFSSQSEHINLYKKPSEVTNFPKNGSLKLMKESLNHVIGDIDATKSLLHES
Sbjct:    1 MEILDFINVMNSLQIANSGEYVIIWVSDKFVNKFELYFKNIKRVNKKMLNVNDNFPTAAMRSMLFLSTATPNPIILEALGLAICHEGFNGICNLKRFTKPQQITMVKSILTAATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVILAGALFLLAAIRYWINEQKLSNLLWKVDFKDVMITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKERKISGESQDTPIEMKLKYNLSEENLDADEFLRKISLSSHNSMNTNCNVNVLPTVDFKESFKSTRFSTHRATLHEYSSPWKNSSFSSQSEHINLYKKPSEVTNFPKNGSLKLMKESLNHVIGDIDATKSLLHES 992          

Query: 1398 MDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKERKISGESQDTPIEMKLKYNLSEENLDADEFLRKISLSSHNSMNTNCNVNVLPTVDFKESFKSTRFSTHRATLHEYSSPWKNSSFSSQSEHINLYKKPSEVTNFPKNGSLKLMKESLNHVIGDIDATKSLLHES 3887
            MDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVI+AGALFLL AIRYWINEQKLSNLLWKVDFKDV ITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKERKISGESQDTPIEMKLKYNLSEENLDADEFLRKISLSSHNSMNTNCNVNVLPTVDFKESFKSTRFSTHRATLHEYSSPWKNSSFSSQSEHINLYKKPSEVTNFPKNGSLKLMKESLNHVIGDIDATKSLLHES
Sbjct:    1 MDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWISGHPPFHEPKCGFSNENCRLELNILALSVCVCVILAGALFLLAAIRYWINEQKLSNLLWKVDFKDVMITDVLPEYDNNKPRNYRNIDNHYSFLVADEFESRRKPRSSCKIRKTFTKIGSYKGMIVSIKFLNHKSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKYYYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPWGSIYRPGNATEIIRKLKNETSNELSSMRPIIDETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLKGLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNVRQERLIKMKIKERKISGESQDTPIEMKLKYNLSEENLDADEFLRKISLSSHNSMNTNCNVNVLPTVDFKESFKSTRFSTHRATLHEYSSPWKNSSFSSQSEHINLYKKPSEVTNFPKNGSLKLMKESLNHVIGDIDATKSLLHES 830          

Query: 1245 AATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWIS--GHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITD---------------------VLPEYDNNK------PRNYRNIDNHY-------SFLVADEFESRRKPRS---------------SCKIRKTFTKIGSYKGMIVSIKFLNH-KSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKY--YYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPW--GSIYRPGNATEIIRKLKNETSNELSSMRPII--DETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLK-GLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNV 3452
               FH  D  +++  A+++   +N S+  G  I +++ ++S   ++G NV++D +GD   ++   S  +M+        VA     +N +  KF+     QI W++    PP   PKCGFSN +C     +   ++ + +++  A+  +V  R++    +L  + W + +  +  T+                     + PE + ++        N  N++NHY              F + R+  +               + +  + F+K G YK  IV+IK + H K IE+ +    +++  KD+N +++ R IG CL+P ++CIL+ YC +GSL+D+L N  I LD IF  SL+ D+ +GMIYLH S I  HGNL++S CLIDSR+++++T FGLQ +R    KD     H L+   Y  Y  LLW +PE L+    +  G+ KGDIYSFAII  E+ ++ G +  G    P    EI+ ++K          RP +  +     + +   + + W++   +RP+ + I+V+ +   K G   NI DN+L  ME+YA NLE LV +RT Q  EEK+K E LL  MLPKSV  QL   + V  E Y  VTIYFSDIVGFTSLSA STPM+V+++LN LYT FDSI+  YDVYKVETIGDAY+VVSGLP RN +LHA EI+ +SL  L+A+ +F I HR +  L +RIG+HSGP  AGVVGLKMPRYCLFGDTVNTASRME+ G+A+KIH S  T  +L   G + + +RG IE+KGKG   TY+L  E  ++
Sbjct:  314 VVAFH--DSVLIYAHALNDCLDKNVSD--GDHITEQMKNKSINGISG-NVHIDSNGDRNADY---SLLDMDPKTETFQVVAI----VNGSDKKFSPVANVQIDWVNVNNRPPLDTPKCGFSNTDCNFGFALTLSTILLVILIIAAVVSIVIYRHFKFHIELKAMNWLIMWDCIETTEKRKARYSDNKVKLKQENLNKLIYPECEESELMNKSFAENEFNMENHYLMTNKDVQLFQGGSFRNARRLSNWSENSLETLAGIQFENLRNHQMFSKTGVYKNGIVAIKPIMHTKKIEINKSLLIQVKKVKDLNNDHICRFIGACLEPQHMCILSEYCPKGSLQDVLENDQIKLDWIFKFSLIQDICRGMIYLH-SNIGPHGNLKSSNCLIDSRFVVKLTDFGLQKLR--GSKD-----HLLEENPYAFYRNLLWTAPEILRNSNSLVEGTVKGDIYSFAIILQEIIYRNGVFYLGEFETPIEPQEIVERVKQFRQ---IPFRPYLGKESENHGSEIDSIIKQMWEEFPLQRPEMRNIKVMFRKFNKAGDSGNILDNLLSRMEQYANNLEGLVTQRTEQYLEEKRKAEDLLYLMLPKSVARQLIRNEPVTAESYESVTIYFSDIVGFTSLSAESTPMQVIELLNHLYTTFDSILENYDVYKVETIGDAYVVVSGLPQRNGNLHAREISRMSLAFLRALFTFQIPHRQDRQLHVRIGMHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQAMKIHISRNTLDVLKTFGSFIITERGQIELKGKGFQTTYWLHGEGEDI 1085          

Query: 1245 AATFHTFDLTMMFFKAIDNIFQRNDSELNGTKILKEIFDQSFKSVTGLNVYMDKHGDAEGNFTVSSYTEMETGQWNITPVAYFIQNLNNTLPKFTMFPGRQISWIS--GHPPFHEPKCGFSNENCRLELNILALSVCVCVIVAGALFLLVAIRYWINEQKLSNLLWKVDFKDVTITD---------------------VLPEYDNNK------PRNYRNIDNHY-------SFLVADEFESRRKPRS---------------SCKIRKTFTKIGSYKGMIVSIKFLNH-KSIELTRKFRQEMQFFKDMNQENLNRIIGVCLDPPNICILTLYCSRGSLKDILSNKDIFLDEIFVASLLFDLIKGMIYLHDSQINYHGNLRTSKCLIDSRWILQITGFGLQSIRYASPKDPSNWPHSLDAEKY--YYKLLWKSPEHLKEPYPMSRGSQKGDIYSFAIIFHELTHQTGPW--GSIYRPGNATEIIRKLKNETSNELSSMRPII--DETQVPNFVKDCLTECWDDVSERRPDFKFIRVILKPLLK-GLRSNIFDNMLLIMEKYAKNLEVLVEERTWQLSEEKKKIERLLLRMLPKSVTEQLKVGQTVIPEHYSCVTIYFSDIVGFTSLSASSTPMEVVQMLNDLYTLFDSIIIEYDVYKVETIGDAYMVVSGLPMRNADLHAGEIASLSLHLLKAIKSFVIRHRPNETLKLRIGIHSGPCVAGVVGLKMPRYCLFGDTVNTASRMEATGEALKIHTSSETKFLLDALGGYCLIKRGNIEVKGKGDMITYFLESEDPNV 3452
               FH  D  +++  A+++   +N S+  G  I +++ ++S   ++G NV++D +GD   ++   S  +M+        VA     +N +  KF+     QI W++    PP   PKCGFSN +C     +   ++ + +++  A+  +V  R++    +L  + W + +  +  T+                     + PE + ++        N  N++NHY              F + R+  +               + +  + F+K G YK  IV+IK + H K IE+ +    +++  KD+N +++ R IG CL+P ++CIL+ YC +GSL+D+L N  I LD IF  SL+ D+ +GMIYLH S I  HGNL++S CLIDSR+++++T FGLQ +R    KD     H L+   Y  Y  LLW +PE L+    +  G+ KGDIYSFAII  E+ ++ G +  G    P    EI+ ++K          RP +  +     + +   + + W++   +RP+ + I+V+ +   K G   NI DN+L  ME+YA NLE LV +RT Q  EEK+K E LL  MLPKSV  QL   + V  E Y  VTIYFSDIVGFTSLSA STPM+V+++LN LYT FDSI+  YDVYKVETIGDAY+VVSGLP RN +LHA EI+ +SL  L+A+ +F I HR +  L +RIG+HSGP  AGVVGLKMPRYCLFGDTVNTASRME+ G+A+KIH S  T  +L   G + + +RG IE+KGKG   TY+L  E  ++
Sbjct:  337 VVAFH--DSVLIYAHALNDCLDKNVSD--GDHITEQMKNKSINGISG-NVHIDSNGDRNADY---SLLDMDPKTETFQVVAI----VNGSDKKFSPVANVQIDWVNVNNRPPLDTPKCGFSNTDCNFGFALTLSTILLVILIIAAVVSIVIYRHFKFHIELKAMNWLIMWDCIETTEKRKARYSDNKVKLKQENLNKLIYPECEESELMNKSFAENEFNMENHYLMTNKDVQLFQGGSFRNARRLSNWSENSLETLAGIQFENLRNHQMFSKTGVYKNGIVAIKPIMHTKKIEINKSLLIQVKKVKDLNNDHICRFIGACLEPQHMCILSEYCPKGSLQDVLENDQIKLDWIFKFSLIQDICRGMIYLH-SNIGPHGNLKSSNCLIDSRFVVKLTDFGLQKLR--GSKD-----HLLEENPYAFYRNLLWTAPEILRNSNSLVEGTVKGDIYSFAIILQEIIYRNGVFYLGEFETPIEPQEIVERVKQFRQ---IPFRPYLGKESENHGSEIDSIIKQMWEEFPLQRPEMRNIKVMFRKFNKAGDSGNILDNLLSRMEQYANNLEGLVTQRTEQYLEEKRKAEDLLYLMLPKSVARQLIRNEPVTAESYESVTIYFSDIVGFTSLSAESTPMQVIELLNHLYTTFDSILENYDVYKVETIGDAYVVVSGLPQRNGNLHAREISRMSLAFLRALFTFQIPHRQDRQLHVRIGMHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQAMKIHISRNTLDVLKTFGSFIITERGQIELKGKGFQTTYWLHGEGEDI 1108