Mitogen-activated protein kinase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024187 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK14 (mitogen-activated protein kinase 14 [Source:HGNC Symbol;Acc:HGNC:6876]) HSP 1 Score: 333.183 bits (853), Expect = 2.941e-111 Identity = 166/347 (47.84%), Postives = 232/347 (66.86%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F +++ + W V RY+NL +G G+ GSVC+AFD++ + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ I+++ T +I +E +NY ++++ +P ++F F + A+DLL KMLVLD ++RI+A AL H Y YHD DE V PY + ES D+ I+ WK +D + +FVP
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNY-IQSLTQMPKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK14 (mitogen-activated protein kinase 14 [Source:HGNC Symbol;Acc:HGNC:6876]) HSP 1 Score: 332.413 bits (851), Expect = 6.711e-111 Identity = 166/347 (47.84%), Postives = 233/347 (67.15%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F +++ + W V RY+NL +G G+ GSVC+AFD++ + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E +NY ++++ +P ++F F + A+DLL KMLVLD ++RI+A AL H Y YHD DE V PY + ES D+ I+ WK +D + +FVP
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNY-IQSLTQMPKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK11 (mitogen-activated protein kinase 11 [Source:HGNC Symbol;Acc:HGNC:6873]) HSP 1 Score: 325.479 bits (833), Expect = 3.258e-108 Identity = 154/336 (45.83%), Postives = 228/336 (67.86%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKD 1134
F +++ + W V R + L+ +G G+ GSVCSA+D+ + VA+KKL+ PFQS A+RTYRE+++L H+ HENVI L+D+F+ + + +F++VY VT L+ DL+ I+ + + +E++ F +YQ+LRGLKYIHS G+IHRDL P N+AVNED ELRILDFGL+R+ D+ MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L + LF G+D DQL++IM++ T +I +E + Y ++++ +P D FR + AIDLL +MLVLD +QR+SA +AL H Y YHD DE PY +++E+ + +E WK+
Sbjct: 8 FYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTY-IQSLPPMPQKDLSSIFR--GANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAK-ERTLEEWKE 339
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK11 (mitogen-activated protein kinase 11 [Source:HGNC Symbol;Acc:HGNC:6873]) HSP 1 Score: 325.479 bits (833), Expect = 3.258e-108 Identity = 154/336 (45.83%), Postives = 228/336 (67.86%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKD 1134
F +++ + W V R + L+ +G G+ GSVCSA+D+ + VA+KKL+ PFQS A+RTYRE+++L H+ HENVI L+D+F+ + + +F++VY VT L+ DL+ I+ + + +E++ F +YQ+LRGLKYIHS G+IHRDL P N+AVNED ELRILDFGL+R+ D+ MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L + LF G+D DQL++IM++ T +I +E + Y ++++ +P D FR + AIDLL +MLVLD +QR+SA +AL H Y YHD DE PY +++E+ + +E WK+
Sbjct: 8 FYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTY-IQSLPPMPQKDLSSIFR--GANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAK-ERTLEEWKE 339
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Match: MAPK12 (mitogen-activated protein kinase 12 [Source:HGNC Symbol;Acc:HGNC:6874]) HSP 1 Score: 312.768 bits (800), Expect = 3.183e-103 Identity = 156/348 (44.83%), Postives = 222/348 (63.79%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLK-AIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F ++ + W V + Y +L+ +G G+ G+VCSA D VAIKKL PFQS+ AKR YRE+++L HM HENVI L+D+F+ +F D Y V P + DL K++ E + E+ I F +YQ+L+GL+YIH+ G+IHRDL P N+AVNED EL+ILDFGL+R+ D MTGYVV+R+YRAPE+I YT +D+WS GCIMAEM+ + LF+G+D DQL++IM++ T F ++ ++E KNY ++ LP ++ F T A++LL KMLVLD QR++A +AL HPY E HD DE Y D+ + + D ++ WK + + +F P
Sbjct: 11 FYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNY----MKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFESLHDTEDEPQVQKYDDSFD-DVDRTLDEWKRVTYKEVLSFKP 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: pmk-1 (Mitogen-activated protein kinase pmk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q17446]) HSP 1 Score: 309.301 bits (791), Expect = 4.447e-102 Identity = 163/344 (47.38%), Postives = 227/344 (65.99%), Query Frame = 1
Query: 139 KIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIET---WKDGIWDCMNTF 1161
+++ S W V + Y NL IG G+ G+VC+A + VAIKK PFQS A+RTYRE+++L M HEN+I L+D+F+ + N + DVYFV+ L+ DLS I+ + + +++I F +YQILRGLKYIHS +IHRDL P NIAVNED EL+ILDFGL+R+ D MTGYV +R+YRAPEI+ +YT +D+WS GCI+AE++ + LF G+D DQL +IM + T E F +I +EE +NY + + + DF + F Q T +AIDLL KML LDP++R +A +A+ H YL YHDETDE P + ++ N DV +T WK IW+ ++ F
Sbjct: 23 ELNRSVWVVPNYYINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILKIQRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNY-IRNLPKMTRRDFKRLFAQATP--QAIDLLEKMLHLDPDRRPTAKEAMEHEYLAAYHDETDE----PIAEEMDLNDDVRADTIDEWKKIIWEEISDF 359
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: pmk-2 (Mitogen-activated protein kinase pmk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MXI4]) HSP 1 Score: 271.937 bits (694), Expect = 2.515e-87 Identity = 150/345 (43.48%), Postives = 214/345 (62.03%), Query Frame = 1
Query: 139 KIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIET----WKDGIWDCMNTF 1161
+++ + W + Y +LK +G G+ G VC+A VAIKK PFQS AKRTYRE+K+L + H+NV+ +ID+F+ + + N+VYFV+ L+ DL I+ + + +E I IYQ+LRGLKYIHS G+IHRDL P NIAVNE E++ILDFGL+R +D MTGYV +R+YRAPEI+ +YT +D+WS GCI+AE++ R LF G+D DQL +IM + T E FW +I +EE +NY ++ DF F + A++LL ML+LDP++RIS + AL H YL Y DE V +DT+ + + T W++ IW+ + F
Sbjct: 37 ELNKTKWVLPQWYNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDEQIQLLIYQVLRGLKYIHSAGIIHRDLKPSNIAVNERCEVKILDFGLARAQDAEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNYIKNRSPIIRQ-DFVTLFPMASP--YALELLEMMLILDPDRRISVSSALRHDYLREYSVPNDEPVA---MDTVTIDPAEERATTLSDWRELIWNEIRLF 375
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: pmk-2 (Mitogen-activated protein kinase pmk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8MXI4]) HSP 1 Score: 271.552 bits (693), Expect = 4.030e-87 Identity = 153/351 (43.59%), Postives = 216/351 (61.54%), Query Frame = 1
Query: 139 KIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIET----------WKDGIWDCMNTF 1161
+++ + W + Y +LK +G G+ G VC+A VAIKK PFQS AKRTYRE+K+L + H+NV+ +ID+F+ + + N+VYFV+ L+ DL I+ + + +E I IYQ+LRGLKYIHS G+IHRDL P NIAVNE E++ILDFGL+R +D MTGYV +R+YRAPEI+ +YT +D+WS GCI+AE++ R LF G+D DQL +IM + T E FW +I +EE +NY ++ DF F + A++LL ML+LDP++RIS + AL H YL Y DE V +DT+ NS V I+ W++ IW+ + F
Sbjct: 37 ELNKTKWVLPQWYNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDEQIQLLIYQVLRGLKYIHSAGIIHRDLKPSNIAVNERCEVKILDFGLARAQDAEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNYIKNRSPIIRQ-DFVTLFPMASP--YALELLEMMLILDPDRRISVSSALRHDYLREYSVPNDEPVA---MDTV-INSIVTIDPAEERATTLSDWRELIWNEIRLF 380
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: jnk-1 (Stress-activated protein kinase jnk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8WQG9]) HSP 1 Score: 245.743 bits (626), Expect = 1.862e-77 Identity = 139/362 (38.40%), Postives = 213/362 (58.84%), Query Frame = 1
Query: 109 IKVMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDD--FMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDL-------------KAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVD--IETWKDGIW 1143
I V + + I + V+ RY+NL++IG G+QG VCSAFD+ VAIKKL+ PFQ+ AKR YRE+K++ ++H+N+I +++ F+ FND+Y V L+ +L ++I + + E + + +YQ+L G++++HS G+IHRDL P NI V D L+ILDFGL+R + MT YVV+RYYRAPE+I Y +D+WS GCI E++ R+LF G D DQ +I++ T F ++ +NY VE P F +++++ +A DLLS+MLV+DP +RIS DAL HPY+ + DE + V AP + N DV+ +++W++ I+
Sbjct: 6 IHVPENYYSVTIGEAQMVVLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQMD-LDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFMMTPYVVTRYYRAPEVIL-GMGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERL-QPTVRNY----VENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRHPYVNVWFDEIE--VYAPPPLPYDHNMDVEQNVDSWREHIF 358
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Match: jnk-1 (Stress-activated protein kinase jnk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8WQG9]) HSP 1 Score: 245.743 bits (626), Expect = 1.862e-77 Identity = 139/362 (38.40%), Postives = 213/362 (58.84%), Query Frame = 1
Query: 109 IKVMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDD--FMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDL-------------KAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVD--IETWKDGIW 1143
I V + + I + V+ RY+NL++IG G+QG VCSAFD+ VAIKKL+ PFQ+ AKR YRE+K++ ++H+N+I +++ F+ FND+Y V L+ +L ++I + + E + + +YQ+L G++++HS G+IHRDL P NI V D L+ILDFGL+R + MT YVV+RYYRAPE+I Y +D+WS GCI E++ R+LF G D DQ +I++ T F ++ +NY VE P F +++++ +A DLLS+MLV+DP +RIS DAL HPY+ + DE + V AP + N DV+ +++W++ I+
Sbjct: 6 IHVPENYYSVTIGEAQMVVLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQMD-LDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFMMTPYVVTRYYRAPEVIL-GMGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERL-QPTVRNY----VENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRHPYVNVWFDEIE--VYAPPPLPYDHNMDVEQNVDSWREHIF 358
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38b (gene:FBgn0024846 transcript:FBtr0080534) HSP 1 Score: 328.561 bits (841), Expect = 9.504e-110 Identity = 168/355 (47.32%), Postives = 228/355 (64.23%), Query Frame = 1
Query: 112 KVMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLF--SSSANRIN-FNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
+ M KF I+ ++W + Y+NL+ +G G+ G VC A VAIKKLA PFQS AKRTYRE+++L HMDHENVI L+D+F A+ ++ F VY VT L+ DL+ II + + ++++ F +YQILRGLKYIHS GVIHRDL P NIAVNED ELRILDFGL+R + MTGYV +R+YRAPEI+ +Y D+WS GCIMAE+L R LF G D QL IM++ T + F +I +E +NY + ++ ++P +F FR + AIDLL KML LD ++RI+A AL HPY+E YHD TDE A Y + E N ++ +E W++ ++ + F P
Sbjct: 3 RKMAKFYKLDINRTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNY-IRSLPVMPRRNFRDIFR--GANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAALYDQSFEEN-ELPVEKWREMVFSEVTAFKP 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38a (gene:FBgn0015765 transcript:FBtr0084580) HSP 1 Score: 313.153 bits (801), Expect = 1.202e-103 Identity = 161/357 (45.10%), Postives = 227/357 (63.59%), Query Frame = 1
Query: 109 IKVMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLF---SSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQY-TEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
+ + +KF I+ ++W + Y++L+ +G G+ G V A ++VAIKKLA PFQS AKRTYRE+++L HMDHENVI L+D+F ++ + NF VY VT L+ DL+ II + + ++++ F +YQILRGLKYIHS GVIHRDL P NIAVNED ELRILDFGL+R ++ MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE++ R LF G D QL IM++ T F +I +E ++Y ++ LPP+ F + + AIDLL KML LD +RI+A +AL HPYLE Y + + E PY + E + D+ ++ WK+ I+ + F P
Sbjct: 3 VSITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSY----IQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPPYDHSFE-DMDLPVDKWKELIYKEVTNFKP 354
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38a (gene:FBgn0015765 transcript:FBtr0300572) HSP 1 Score: 313.153 bits (801), Expect = 1.202e-103 Identity = 161/357 (45.10%), Postives = 227/357 (63.59%), Query Frame = 1
Query: 109 IKVMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLF---SSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQY-TEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
+ + +KF I+ ++W + Y++L+ +G G+ G V A ++VAIKKLA PFQS AKRTYRE+++L HMDHENVI L+D+F ++ + NF VY VT L+ DL+ II + + ++++ F +YQILRGLKYIHS GVIHRDL P NIAVNED ELRILDFGL+R ++ MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE++ R LF G D QL IM++ T F +I +E ++Y ++ LPP+ F + + AIDLL KML LD +RI+A +AL HPYLE Y + + E PY + E + D+ ++ WK+ I+ + F P
Sbjct: 3 VSITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSY----IQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPPYDHSFE-DMDLPVDKWKELIYKEVTNFKP 354
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38a (gene:FBgn0015765 transcript:FBtr0084581) HSP 1 Score: 313.153 bits (801), Expect = 1.202e-103 Identity = 161/357 (45.10%), Postives = 227/357 (63.59%), Query Frame = 1
Query: 109 IKVMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLF---SSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQY-TEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
+ + +KF I+ ++W + Y++L+ +G G+ G V A ++VAIKKLA PFQS AKRTYRE+++L HMDHENVI L+D+F ++ + NF VY VT L+ DL+ II + + ++++ F +YQILRGLKYIHS GVIHRDL P NIAVNED ELRILDFGL+R ++ MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE++ R LF G D QL IM++ T F +I +E ++Y ++ LPP+ F + + AIDLL KML LD +RI+A +AL HPYLE Y + + E PY + E + D+ ++ WK+ I+ + F P
Sbjct: 3 VSITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSY----IQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPPYDHSFE-DMDLPVDKWKELIYKEVTNFKP 354
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Match: p38c (gene:FBgn0267339 transcript:FBtr0084582) HSP 1 Score: 270.011 bits (689), Expect = 5.816e-87 Identity = 152/355 (42.82%), Postives = 209/355 (58.87%), Query Frame = 1
Query: 118 MRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSA-NRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYL----EFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
M +F I+ S W YE ++ +G GS G V + Y A+K+L PF+ ++ AK TYRE+++L HM+H NVI L+++F A N + F VY VT L+ DL + + M ++ I +YQILRGLKYIHS GV+HRDL P NIAVN ++E+RILDFGLSR D MT +V + +Y APEIIF YT ID+WS GCI+AE++ R+LFRG + Q+R ++ I T F I E +NY LE L DFH F Y D++AIDL+ KML + P +RI+A +A+LHPYL E +H D AP D N + ++ WK+ + + F P
Sbjct: 1 MPEFVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILRGLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQYTKAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNY-LEGYPLRQRCDFHHLFMGY--DVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDT---APVYDQNFENMVLPVKCWKELVSHEIRNFRP 349
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk11 (mitogen-activated protein kinase 11 [Source:ZFIN;Acc:ZDB-GENE-040625-75]) HSP 1 Score: 337.035 bits (863), Expect = 5.865e-113 Identity = 165/345 (47.83%), Postives = 234/345 (67.83%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTF 1161
F +++ + W V RY+NL +G G+ GSVCSA+D + VA+KKL+ PFQS ++RTYRE+++L HM HENVI L+D+F+ +A+ FN+VY VT L+ DL+ I+ + + +E++ F IYQ+LRGLKYIHS G+IHRDL P N+AVNED ELRILDFGL+R+ DD MTGYV +R+YRAPEI+ +Y +D+WS GCIM E+L ++LF GND DQL++IM++ T +I +E + Y ++++ +P D + FR + A+DLL KMLVLD + RISA++AL HPY YHD DE PY T ES D +E WK+ +++ ++ F
Sbjct: 7 FYRQELNKTVWEVPERYQNLTPVGSGAYGSVCSAYDVRLRQKVAVKKLSRPFQSLIHSRRTYRELRLLKHMKHENVIGLLDVFTPAASLEEFNEVYLVTNLMGADLNNIVKFQRLSDEHVQFLIYQLLRGLKYIHSAGLIHRDLKPSNVAVNEDCELRILDFGLARQTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMGELLKGKVLFPGNDYIDQLKRIMEVVGTPTPDVLKKISSEHAQKY-IQSLPHMPQQDLGKIFR--GANPLAVDLLKKMLVLDCDGRISASEALCHPYFSQYHDPEDEPEAPPYDQTPESK-DRTMEEWKELVFEEVSNF 347
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 332.798 bits (852), Expect = 2.707e-111 Identity = 166/349 (47.56%), Postives = 231/349 (66.19%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKI 1173
F +++ + W V +Y+NL +G G+ GSVCSAFD++ VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ IM + T G +I +E + Y + ++ +P +F F + +A+DLL KMLVLD ++RI+A +AL HPY YHD DE P+ + ES ++DIE WK ++ M +F P +
Sbjct: 9 FYRQEVNKTIWEVPVQYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELRLLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNVTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMLLVGTPGPGLLMKISSESARTY-ISSLPQMPKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEAEPFDQSFESR-ELDIEEWKRQTYEEMISFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 332.798 bits (852), Expect = 2.707e-111 Identity = 166/349 (47.56%), Postives = 231/349 (66.19%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKI 1173
F +++ + W V +Y+NL +G G+ GSVCSAFD++ VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ IM + T G +I +E + Y + ++ +P +F F + +A+DLL KMLVLD ++RI+A +AL HPY YHD DE P+ + ES ++DIE WK ++ M +F P +
Sbjct: 9 FYRQEVNKTIWEVPVQYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELRLLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNVTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMLLVGTPGPGLLMKISSESARTY-ISSLPQMPKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEAEPFDQSFESR-ELDIEEWKRQTYEEMISFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk14b (mitogen-activated protein kinase 14b [Source:NCBI gene;Acc:266756]) HSP 1 Score: 332.028 bits (850), Expect = 5.364e-111 Identity = 167/354 (47.18%), Postives = 232/354 (65.54%), Query Frame = 1
Query: 112 KVMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKI 1173
K F +++ + W V RY+NL +G G+ GSVCSAFD + + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+FS + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILR LKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E +NY + ++ +P +F F + A+DLL KMLVLD ++RI+A+ AL HPY YHD DE PY + ES D++IE WK ++ + +F P +
Sbjct: 4 KARPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCSAFDGKAGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFSPATSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRALKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNY-ISSLPHMPKRNFADVF--IGANPLAVDLLEKMLVLDTDKRITASQALAHPYFAQYHDPDDEPEADPYDQSFESR-DLEIEEWKSLTYEEVMSFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 331.643 bits (849), Expect = 8.741e-111 Identity = 164/349 (46.99%), Postives = 232/349 (66.48%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKI 1173
F +++ + W V +Y+NL +G G+ GSVCSAFD++ VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E + Y + ++ +P +F F + +A+DLL KMLVLD ++RI+A +AL HPY YHD DE P+ + ES ++DIE WK ++ M +F P +
Sbjct: 9 FYRQEVNKTIWEVPVQYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELRLLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNVTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPSSLISRMPSHEARTY-ISSLPQMPKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEAEPFDQSFESR-ELDIEEWKRQTYEEMISFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: pde6a (phosphodiesterase 6A [Source:Xenbase;Acc:XB-GENE-988755]) HSP 1 Score: 342.043 bits (876), Expect = 1.039e-114 Identity = 166/337 (49.26%), Postives = 231/337 (68.55%), Query Frame = 1
Query: 157 WHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
W V RY+NL +G G+ GSVCSAFD+ ++ VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS G+IHRDL P N+AVNED EL+ILDFGL+R D+ MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ I+++ T +I +E +NY ++++ +P ++F F + +A+DLL KMLVLD ++RI+A +AL HPY YHD DE + PY + ES ++DIE WK ++ + FVP
Sbjct: 19 WEVPDRYQNLTPVGSGAYGSVCSAFDTRTELRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAKSFEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHTDEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPEPELLQKISSEAARNY-IQSLPYMPKMNFEDVF--LGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPIAEPYDQSFESR-ELDIEEWKRLTYEEVICFVP 351
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: pde6a (phosphodiesterase 6A [Source:Xenbase;Acc:XB-GENE-988755]) HSP 1 Score: 341.658 bits (875), Expect = 1.320e-114 Identity = 166/337 (49.26%), Postives = 232/337 (68.84%), Query Frame = 1
Query: 157 WHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
W V RY+NL +G G+ GSVCSAFD+ ++ VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS G+IHRDL P N+AVNED EL+ILDFGL+R D+ MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E +NY ++++ +P ++F F + +A+DLL KMLVLD ++RI+A +AL HPY YHD DE + PY + ES ++DIE WK ++ + FVP
Sbjct: 19 WEVPDRYQNLTPVGSGAYGSVCSAFDTRTELRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAKSFEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHTDEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPSYLINRMPSHEARNY-IQSLPYMPKMNFEDVF--LGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPIAEPYDQSFESR-ELDIEEWKRLTYEEVICFVP 351
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:100101766]) HSP 1 Score: 337.421 bits (864), Expect = 6.800e-113 Identity = 170/355 (47.89%), Postives = 243/355 (68.45%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP---KIENL 1182
F +++ + W V RY+ L +G G+ GSVCSA+D++ + VA+KKL+ PFQS A+RTYRE+++L HM HENVI L+D+F+ S + NFN+VY VT L+ DL+ I+ + + +++I F IYQ+LRGLKYIHS G+IHRDL P N+AVNED ELRILDFGL+R+ DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L + LF GND DQL++IM++ T + F +I +E + Y +E++ +P D + F + + AIDLL KML+LD ++RI+AT+AL HPY YHD DE PY ++ E N + I+ WK+ ++ + +F KI+NL
Sbjct: 7 FYKQELNKTVWEVPDRYQRLTPVGSGAFGSVCSAYDTKTRQKVAVKKLSRPFQSLVHARRTYRELRLLKHMKHENVIGLLDVFTPSTSGENFNEVYLVTNLMGADLNNIVKCQKLTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGTPNSEFLLKISSEHARRY-IESLPYMPQQDLKEVF--HGANPLAIDLLEKMLILDSDKRITATEALAHPYFVQYHDPDDEPEAEPYDESTE-NKERTIDEWKEITYEEVISFKSQDVKIDNL 357
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: mapk12 (mitogen-activated protein kinase 12 [Source:NCBI gene;Acc:549834]) HSP 1 Score: 333.569 bits (854), Expect = 1.825e-111 Identity = 167/344 (48.55%), Postives = 226/344 (65.70%), Query Frame = 1
Query: 157 WHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPI---DFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIEN 1179
W V RY +L +G G+ G+VCS+ D+ VAIKKL PFQS+ AKR YRE+++L HM HENVI L+D+F+ + NFND Y V P + DL KI+ E + E+ I F +YQILRGLKYIHS G+IHRDL P N+AVNED EL+ILDFGL+R D MTGYVV+R+YRAPE+I +YT +D+WS GCIMAEM R LF+GND DQL +IM+I T + F ++ + + KNY ++ LP + DF R Y L A+++L KMLVLD +RI+AT+AL HPY E +HD DE+ PY D+ + N ++ +E W+ + ++ P + +
Sbjct: 21 WEVKERYRDLVAVGSGAYGTVCSSLDTRTGTKVAIKKLYRPFQSELFAKRAYRELRLLKHMQHENVIGLLDVFTPDSTLENFNDFYLVMPFMGTDLGKIMKHEKLSEDRIQFLVYQILRGLKYIHSAGIIHRDLKPGNLAVNEDCELKILDFGLARHTDSEMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMYTGRPLFKGNDHLDQLTEIMKITGTPTQDFVQKLQSPDAKNY----IKSLPKVQKKDFGSLLR-YANPL-AVNILEKMLVLDAEKRITATEALAHPYFEQFHDIDDETEAEPYDDSFD-NVNLPLEEWRRLTHKELTSYKPLVAD 357
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:100101766]) HSP 1 Score: 325.094 bits (832), Expect = 5.655e-108 Identity = 164/339 (48.38%), Postives = 225/339 (66.37%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNY-FLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGI 1140
F +++ + W V RY+ L +G G+ GSVCSA+D++ + VA+KKL+ PFQS A+RTYRE+++L HM HENVI L+D+F+ S + NFN+VY VT L+ DL+ I+ + + +++I F IYQ+LRGLKYIHS G+IHRDL P N+AVNED ELRILDFGL+R+ DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L + LF GND DQL++IM++ T + F +I +E + FL LKAIDLL KML+LD ++RI+AT+AL HPY YHD DE PY ++ E N + I+ WK +
Sbjct: 7 FYKQELNKTVWEVPDRYQRLTPVGSGAFGSVCSAYDTKTRQKVAVKKLSRPFQSLVHARRTYRELRLLKHMKHENVIGLLDVFTPSTSGENFNEVYLVTNLMGADLNNIVKCQKLTDDHIQFLIYQLLRGLKYIHSAGIIHRDLKPSNLAVNEDCELRILDFGLARQADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLKGKALFPGNDYIDQLKRIMEVVGTPNSEFLLKISSEHVSRFSFL---------------------LKAIDLLEKMLILDSDKRITATEALAHPYFVQYHDPDDEPEAEPYDESTE-NKERTIDEWKGKV 323
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk14 (mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865]) HSP 1 Score: 330.872 bits (847), Expect = 1.623e-110 Identity = 166/347 (47.84%), Postives = 231/347 (66.57%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F +++ + W V RY+NL +G G+ GSVC+AFD++ VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ I+++ T +I +E +NY ++++ +P ++F F + A+DLL KMLVLD ++RI+A AL H Y YHD DE V PY + ES D+ I+ WK +D + +FVP
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNY-IQSLAQMPKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk14 (mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865]) HSP 1 Score: 330.487 bits (846), Expect = 2.560e-110 Identity = 166/347 (47.84%), Postives = 232/347 (66.86%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F +++ + W V RY+NL +G G+ GSVC+AFD++ VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E +NY ++++ +P ++F F + A+DLL KMLVLD ++RI+A AL H Y YHD DE V PY + ES D+ I+ WK +D + +FVP
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNY-IQSLAQMPKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk11 (mitogen-activated protein kinase 11 [Source:MGI Symbol;Acc:MGI:1338024]) HSP 1 Score: 327.02 bits (837), Expect = 5.228e-109 Identity = 156/347 (44.96%), Postives = 232/347 (66.86%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F +++ + W V R + L+ +G G+ GSVCSA+D+ + VA+KKL+ PFQS A+RTYRE+++L H+ HENVI L+D+F+ + + +F++VY VT L+ DL+ I+ + + +E++ F +YQ+LRGLKYIHS G+IHRDL P N+AVNED ELRILDFGL+R+ D+ MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L + LF GND DQL++IM++ T +I +E + Y ++++ +P D F + + AIDLL +MLVLD +QR+SA +AL H Y YHD DE PY +++E+ +E WK+ + + +F P
Sbjct: 8 FYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTY-IQSLPPMPQKDLSSVF--HGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAEPYDESVEAKERT-LEEWKELTYQEVLSFKP 350
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk12 (mitogen-activated protein kinase 12 [Source:MGI Symbol;Acc:MGI:1353438]) HSP 1 Score: 323.939 bits (829), Expect = 1.201e-107 Identity = 162/350 (46.29%), Postives = 226/350 (64.57%), Query Frame = 1
Query: 121 RKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTE-DLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
+ F ++ + W V + Y++L+ +G G+ G+VCSA DS VAIKKL PFQS+ AKR YRE+++L HM HENVI L+D+F+ + +F D Y V P + DL K++ E + E+ I F +YQ+L+GLKYIH+ GVIHRDL P N+AVNED EL+ILDFGL+R+ D MTGYVV+R+YRAPE+I YT +D+WS GCIMAEM+ +ILF+GND DQL++IM+I T F ++ + E KNY +E LP ++ F T +A++LL +MLVLD QR++A +AL HPY E D DE Y D+ + + D +E WK + + +F P
Sbjct: 9 KGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLMKHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKLQSAEAKNY----MEGLPELEKKDFASVLTNASPQAVNLLERMLVLDAEQRVTAAEALTHPYFESLRDTEDEPKAQKYDDSFD-DVDRTLEEWKRVTYKEVLSFKP 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Match: Mapk13 (mitogen-activated protein kinase 13 [Source:MGI Symbol;Acc:MGI:1346864]) HSP 1 Score: 301.212 bits (770), Expect = 7.456e-99 Identity = 153/350 (43.71%), Postives = 222/350 (63.43%), Query Frame = 1
Query: 121 RKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDES-VGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
R F I+ + W + Y +G G+ G+VCSA D VAIKKL+ PFQS+ AKR YRE+ +L HM HENVI L+D+F+ +++ +F+D Y V P + DL KI+ EF E+ + + +YQ+L+GLKYIHS G++HRDL P N+AVNED EL+ILDFGL+R D MTGYVV+R+YRAPE+I +Y +D+WS GCIMAEML + LF+G D DQL QI+++ F ++ + K+Y ++++ P DF Q F + + +A DLL KML LD ++R++A AL HP+ E + D +E+ P+ D LE + + ++ WK I+ ++ F P
Sbjct: 7 RGFYKQDINKTAWELPKTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHENVIGLLDVFTPASSLRSFHDFYLVMPFMQTDLQKIMGMEF-SEDKVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNEDCELKILDFGLARHTDTEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLKDKAAKSY-IQSLPQSPKKDFTQLFPRASP--QAADLLDKMLELDVDKRLTAAQALAHPFFEPFRDPEEETEAQQPFDDALE-HEKLSVDEWKQHIYKEISNFSP 351
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|P47812|MK14_XENLA (Mitogen-activated protein kinase 14 OS=Xenopus laevis OX=8355 GN=mapk14 PE=2 SV=1) HSP 1 Score: 338.191 bits (866), Expect = 1.544e-112 Identity = 164/337 (48.66%), Postives = 229/337 (67.95%), Query Frame = 1
Query: 157 WHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
W V RY+NL +G G+ GSVCS+FD+ + +A+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+FS + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS G+IHRDL P N+AVNED EL+ILDFGL+R D+ MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ I+++ T +I +E +NY ++++ +P ++F F + +A+DLL KMLVLD ++RI+A +AL H Y YHD DE + PY + ES ++DIE WK ++ + FVP
Sbjct: 19 WEVPDRYQNLTPVGSGAYGSVCSSFDTRTALRIAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFSPAKSFEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHTDEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPEPELLQKISSEAARNY-IQSLPYMPKMNFEDVF--LGANPQAVDLLEKMLVLDTDKRITAAEALAHSYFAQYHDPDDEPIAEPYDQSFESR-ELDIEEWKRLTYEEVTCFVP 351
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|Q9I958|MK14B_CYPCA (Mitogen-activated protein kinase 14B OS=Cyprinus carpio OX=7962 GN=mapk14b PE=1 SV=1) HSP 1 Score: 333.569 bits (854), Expect = 9.769e-111 Identity = 167/349 (47.85%), Postives = 230/349 (65.90%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKI 1173
F +++ + W V RY+NL +G G+ GSVCSA D++ + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D FS + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E +NY + ++ +P +F F + A+DLL KMLVLD ++RI+A+ AL HPY YHD DE PY + ES D+DIE WK ++ + +F P +
Sbjct: 9 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCSALDTKSGLRVAVKKLSRPFQSMIHAKRTYRELRLLKHMKHENVIGLLDAFSPATCLAGFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNY-INSLSYMPKRNFADVF--VGANPMAVDLLEKMLVLDTDKRITASQALAHPYFAQYHDPDDEPEADPYDQSFESR-DLDIEEWKRLTYEEVISFEPPV 353
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|O02812|MK14_CANLF (Mitogen-activated protein kinase 14 OS=Canis lupus familiaris OX=9615 GN=MAPK14 PE=2 SV=3) HSP 1 Score: 333.569 bits (854), Expect = 1.162e-110 Identity = 166/347 (47.84%), Postives = 232/347 (66.86%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F +++ + W V RY+NL +G G+ GSVC+AFD++ + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ I+++ T +I +E +NY ++++ +P ++F F + A+DLL KMLVLD ++RI+A AL H Y YHD DE V PY + ES D+ I+ WK +D + +FVP
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGADLLKKISSESARNY-IQSLTQMPKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVVSFVP 350
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|Q16539|MK14_HUMAN (Mitogen-activated protein kinase 14 OS=Homo sapiens OX=9606 GN=MAPK14 PE=1 SV=3) HSP 1 Score: 333.183 bits (853), Expect = 1.413e-110 Identity = 166/347 (47.84%), Postives = 232/347 (66.86%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F +++ + W V RY+NL +G G+ GSVC+AFD++ + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ I+++ T +I +E +NY ++++ +P ++F F + A+DLL KMLVLD ++RI+A AL H Y YHD DE V PY + ES D+ I+ WK +D + +FVP
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNY-IQSLTQMPKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Match: sp|Q95NE7|MK14_PANTR (Mitogen-activated protein kinase 14 OS=Pan troglodytes OX=9598 GN=MAPK14 PE=2 SV=3) HSP 1 Score: 332.413 bits (851), Expect = 3.223e-110 Identity = 166/347 (47.84%), Postives = 233/347 (67.15%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F +++ + W V RY+NL +G G+ GSVC+AFD++ + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E +NY ++++ +P ++F F + A+DLL KMLVLD ++RI+A AL H Y YHD DE V PY + ES D+ I+ WK +D + +FVP
Sbjct: 8 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNY-IQSLTQMPKMNFANVF--IGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR-DLLIDEWKSLTYDEVISFVP 350
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A4E0RTP7 (Mitogen-activated protein kinase OS=Fasciola hepatica OX=6192 GN=D915_005042 PE=4 SV=1) HSP 1 Score: 360.918 bits (925), Expect = 1.037e-118 Identity = 165/352 (46.88%), Postives = 242/352 (68.75%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL 1182
F +++ S W V RY++L ++GHG+ G VC+A+D+ + VAIKKL PF+ ++ AKRT+RE+KIL H+DHEN++CLID FS + F DVY VTPL+ DL +I + + + +I F +YQILR LKY+HS G++HRDL P NIAVNED EL+ILDFGL+R+KD+ MTGYV +R+YRAPEI+ +Y +D+WS CIMAE+ + LF G + DQ++ IM++ E +I ++ ++ F+ ++ + P D + +F ++ D AIDLL K+L LDP++R +AT AL HPY + YHD+ DE VG P++D LE +DV +E WK +W+ + FVPK+++L
Sbjct: 18 FVQTELNLSIWLVPERYQDLTLLGHGAYGVVCTAYDTRLQRRVAIKKLTKPFEDKEYAKRTHRELKILSHVDHENILCLIDAFSPQTSLEQFKDVYLVTPLMGADLEAVIRSQSLSDGHIRFLVYQILRALKYMHSAGLVHRDLKPVNIAVNEDCELKILDFGLARRKDEVMTGYVTTRWYRAPEIMLNWMHYNESVDIWSTACIMAELRTRKPLFTGKNHIDQIKMIMRVLGKPDEECMKKITSQNARD-FVASIAIEEPQDLYTYFAGFSPD--AIDLLQKLLHLDPDRRYTATQALAHPYFQGYHDDQDEPVGEPFIDPLEDRTDVSLEEWKKHVWNALENFVPKLDSL 366
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A4S2L8C7 (Mitogen-activated protein kinase OS=Opisthorchis felineus OX=147828 GN=CRM22_009273 PE=4 SV=1) HSP 1 Score: 346.28 bits (887), Expect = 4.972e-113 Identity = 160/352 (45.45%), Postives = 234/352 (66.48%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL 1182
F T +++ W V RY +L +IGHG G+VCSA+DS+ VAIKKL PF + AKRTYRE++IL H+ HEN++CLID FS ++ F D+Y VTP ++ DLS ++ + + + +I F IYQ+LR LKY+HS G+IHRDL P NI VNED EL++LDFGL+R++DD MTGYV +R+YRAPEI+ ++Y ++D+WS CIM+E+ + LF G + DQLR+I+ + E + ++ ++ F++ +E+ P D + +F + ED +DLL +L LDP++R +A+ AL H Y E YHDE DE G ++D LE DV ++ WK+ IW + FVPK+ +L
Sbjct: 20 FVTVDFNHTQWTVPERYRDLSLIGHGVYGAVCSAYDSQLHRRVAIKKLTKPFDDSEYAKRTYRELRILAHVSHENILCLIDAFSPQSSLDTFKDLYLVTPFMAADLSAVVRTQDLSDSHIRFLIYQLLRALKYLHSCGLIHRDLKPGNIGVNEDCELKLLDFGLARQRDDEMTGYVATRWYRAPEIMLNWTHYNEQVDIWSVACIMSELRTRKPLFPGRNHIDQLRRIICLLGKPDELYMEKVTGAGARS-FIDNLEVTDPSDLNVYFSDFPED--GVDLLRHLLQLDPDRRYTASQALAHRYFELYHDEQDEPTGDRFVDALEEAKDVSVQEWKEHIWKTLENFVPKLNSL 368
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A2U9K5Z7 (Mitogen-activated protein kinase OS=Bugula neritina OX=10212 PE=2 SV=1) HSP 1 Score: 344.739 bits (883), Expect = 1.166e-112 Identity = 164/342 (47.95%), Postives = 234/342 (68.42%), Query Frame = 1
Query: 157 WHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL 1182
W V RY+ L +G G+ G VCSA D+E + VAIKKL PFQS A+RT+RE+K+L HM+HEN+I L+ +F+ + + F+DVY VT L+ DL+ I+ + + +E++ F IYQILRGLKY+HS G+IHRDL P NIAVNED EL+ILDFGL+R+ DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE++ + LF GNDQ DQL +IM++ T F +I ++E + Y + +++++P DF ++F D A+DLL +ML LD ++RI+A +AL HPYL YHDE+DE P+ D+ E + + + W+ +W N F+P+ E L
Sbjct: 25 WEVPKRYQMLSPVGTGAYGQVCSALDTEKNMKVAIKKLTRPFQSPIHARRTFREIKMLKHMNHENIIGLLAIFTPATSIEKFSDVYLVTNLMGADLNNIVRTQKLTDEHVQFLIYQILRGLKYVHSAGIIHRDLKPSNIAVNEDCELKILDFGLARQADDSMTGYVATRWYRAPEIMLNWMHYNRTVDIWSVGCIMAELMTGKTLFPGNDQIDQLHKIMKLVGTPGPEFLKRITSDEARRY-IASLQVMPKRDFREYFLGSNPD--ALDLLERMLDLDADRRITAPEALRHPYLAQYHDESDEPEAEPFDDSFE-HVEKTVADWRLAVWGETNNFIPREEQL 362
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: G7YQ71 (Mitogen-activated protein kinase OS=Clonorchis sinensis OX=79923 GN=CLF_106854 PE=4 SV=1) HSP 1 Score: 344.739 bits (883), Expect = 2.924e-112 Identity = 160/352 (45.45%), Postives = 233/352 (66.19%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL 1182
F T +++ W V RY +L +IGHG G+VCSA+DS+ VAIKKL PF + AKRTYRE++IL H+ HEN++CLID FS ++ F D+Y VTP ++ DLS ++ + + + +I F IYQ+LR LKY+HS G+IHRDL P NI VNED EL++LDFGL+R++DD MTGYV +R+YRAPEI+ ++Y ++D+WS CIM+E+ + LF G + DQLR+I+ + E + ++ ++ F++ +E+ P D +F + ED +DLL +L LDP++R +A+ AL H Y E YHDE DE G ++D LE DV ++ WK+ IW + FVPK+ +L
Sbjct: 32 FVTVDFNHTQWTVPERYRDLSLIGHGVYGAVCSAYDSQLHRRVAIKKLTKPFDDSEYAKRTYRELRILAHVSHENILCLIDAFSPQSSLDTFKDLYLVTPFMAADLSAVVRTQDLSDSHIRFLIYQLLRALKYLHSCGLIHRDLKPGNIGVNEDCELKLLDFGLARQRDDEMTGYVATRWYRAPEIMLNWTHYNEQVDIWSVACIMSELRTRKPLFPGRNHIDQLRRIICLLGKPDELYMEKVTGAGARS-FIDNLEVTNPPDLSVYFSDFPED--GVDLLRHLLQLDPDRRYTASQALAHRYFELYHDEQDEPTGDRFVDALEEAKDVSVQEWKEHIWKTLEDFVPKLNSL 380
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Match: A0A2I4CR37 (Mitogen-activated protein kinase OS=Austrofundulus limnaeus OX=52670 GN=LOC106531214 PE=4 SV=1) HSP 1 Score: 343.199 bits (879), Expect = 5.509e-112 Identity = 164/345 (47.54%), Postives = 237/345 (68.70%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTF 1161
F +++ + W V RY+NL +G G+ GSVCSA+D + VA+KKL+ PFQS ++R+YRE+++L HM HENVI L+D+F+ +A+ +FN++Y VT L+ DL+ I+ + + +E++ F IYQ+LRGLKYIHS G+IHRDL P N+AVNED ELRILDFGL+R+ DD MTGYV +R+YRAPEI+ +Y +D+WS GCIM E+L ++LF G D DQL++IM++ T +IC+E + Y ++++ +PP D + FR + A+DLL +MLVLD ++RISA +AL HPY YHD DE PY TLES D +E WK+ +++ + +F
Sbjct: 7 FYRQELNKTVWEVPERYQNLTPVGSGAYGSVCSAYDVVLRQKVAVKKLSRPFQSLIHSRRSYRELRLLKHMKHENVIGLLDVFTPAASLEDFNELYLVTNLMGADLNNIVKFQRLSDEHVQFLIYQLLRGLKYIHSAGLIHRDLKPSNVAVNEDCELRILDFGLARQTDDEMTGYVATRWYRAPEIMLNWMHYNQNVDIWSVGCIMGELLKGKVLFPGTDYIDQLKRIMEVVGTPTPEMLKKICSEHAQKY-IQSLPFMPPQDLEKIFR--GANPLAVDLLKRMLVLDCDERISAGEALSHPYFSQYHDPEDEPEAPPYDQTLESK-DRTLEEWKELVFEEVKSF 347
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk11 (mitogen-activated protein kinase 11 [Source:NCBI gene;Acc:103035641]) HSP 1 Score: 340.502 bits (872), Expect = 2.086e-114 Identity = 165/345 (47.83%), Postives = 235/345 (68.12%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTF 1161
F +++ + W V RY+NL +G G+ GSVCSA+D + VA+KKL+ PFQS ++R+YRE+++L HM HENVI L+D+FS +A+ FN+VY VT L+ DL+ I+ + + +E++ F IYQ+LRGLKYIHS G+IHRDL P N+AVNED ELRILDFGL+R+ DD MTGYV +R+YRAPEI+ +Y +D+WS GCIM E+L ++LF GND DQL++IM++ T +I +E + Y ++++ +P D + FR + A+DLL KMLVLD ++RISA++AL HPY YHD DE AP D + D +E WKD +++ +N+F
Sbjct: 7 FYRQELNKTVWEVPERYQNLTPVGSGAYGSVCSAYDVRLRQKVAVKKLSRPFQSLIHSRRSYRELRLLKHMKHENVIGLLDVFSPAASLEEFNEVYLVTNLMGADLNNIVKFQRLSDEHVQFLIYQLLRGLKYIHSAGLIHRDLKPSNVAVNEDCELRILDFGLARQTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMGELLKGKVLFPGNDYIDQLKRIMEVVGTPTPDLLKKISSEHAQKY-IQSLPYMPQQDLGKIFR--GANPMAVDLLKKMLVLDCDRRISASEALCHPYFSQYHDPEDEP-EAPLYDQTPESKDCTLEEWKDLVFEEVNSF 347
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk14b (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:103028137]) HSP 1 Score: 331.643 bits (849), Expect = 6.646e-111 Identity = 165/349 (47.28%), Postives = 233/349 (66.76%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKI 1173
F +++ + W V RY+NL +G G+ GSVCSA+D + + +A+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + N FNDVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E +NY + ++ +P +F F + A+DLL KMLVLD ++RI+A++AL HPY YHD DE PY + ES ++DIE WK ++ + +F P +
Sbjct: 9 FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCSAYDIQSGLKIAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATNLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNY-INSLPHMPKRNFADVF--IGANPLAVDLLEKMLVLDTDKRITASEALAHPYFAQYHDPDDEPEADPYDQSFESR-ELDIEEWKRLTYEEVLSFEPPV 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk14a (mitogen-activated protein kinase 14A-like [Source:NCBI gene;Acc:103046996]) HSP 1 Score: 330.487 bits (846), Expect = 1.904e-110 Identity = 166/350 (47.43%), Postives = 231/350 (66.00%), Query Frame = 1
Query: 124 KFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKI 1173
KF +++ + W V RY+NL +G G+ GSVCSA D + + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQI+RGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E +NY + ++ +P +F F + +A+DLL KMLVLD ++RI+A +AL HPY YHD DE PY + ES ++DIE WK ++ + F P I
Sbjct: 8 KFYRQEVNKTIWEVPLRYQNLSPVGSGAYGSVCSAVDEKMGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDAFTPATSLEGFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQIIRGLKYIHSADIIHRDLKPGNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRALFPGTDHINQLQQIMRLTGTPPSSLISRMPSHEARNY-IHSLPNMPKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEADPYDQSFESR-ELDIEEWKRLTYEEVINFEPPI 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk14a (mitogen-activated protein kinase 14A-like [Source:NCBI gene;Acc:103046996]) HSP 1 Score: 328.176 bits (840), Expect = 1.372e-109 Identity = 166/350 (47.43%), Postives = 229/350 (65.43%), Query Frame = 1
Query: 124 KFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKI 1173
KF +++ + W V RY+NL +G G+ GSVCSA D + + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D F+ + + FNDVY VT L+ DL+ I+ + + ++++ F IYQI+RGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ IM + T +I ++ +NY + ++ +P +F F + +A+DLL KMLVLD ++RI+A +AL HPY YHD DE PY + ES ++DIE WK ++ + F P I
Sbjct: 8 KFYRQEVNKTIWEVPLRYQNLSPVGSGAYGSVCSAVDEKMGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDAFTPATSLEGFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQIIRGLKYIHSADIIHRDLKPGNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRALFPGTDHIDQLKLIMMLVGTPGPELLKKISSDSARNY-IHSLPNMPKRNFADVF--IGANPQAVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPDDEPEADPYDQSFESR-ELDIEEWKRLTYEEVINFEPPI 353
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Match: mapk12b (mitogen-activated protein kinase 12-like [Source:NCBI gene;Acc:103035956]) HSP 1 Score: 309.301 bits (791), Expect = 4.477e-102 Identity = 156/359 (43.45%), Postives = 236/359 (65.74%), Query Frame = 1
Query: 109 IKVMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQ-FFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL 1182
+++ F +++ + W V RY +L +G G+ G+V SA D + + VAIKKL PFQS+ AKR YRE+++L HM HENVI L+D+F+S + F D Y V P + DL K++ E + E+ + F +YQ+LRGLKYIHS G+IHRDL P N+AVN++ EL+ILDFGL+R+ D MTGYVV+R+YRAPE+I +Y+ +D+WS GCIMAEML+ R LF+GND DQLR+IM+I T + F ++ +++ KNY + ++ +P D H FF+ +E + A++ +ML+LDP+ R+SA AL P + + +E+ PY +++ N+D+ +E WK + + +F P + L
Sbjct: 3 LRIRAGFYRQEVNKTVWDVPERYRDLIQVGTGAYGTVSSAIDRKAGVRVAIKKLHRPFQSRLFAKRAYRELRLLKHMKHENVIGLLDVFTSEISLDRFQDFYLVMPFMGTDLGKLMKMERLCEDRVQFLVYQMLRGLKYIHSAGIIHRDLKPGNLAVNQNCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMHYSQTVDIWSVGCIMAEMLLGRPLFKGNDHLDQLREIMKITGTPGQDFILKLQSQDAKNY-IRSLPKVPKKDLHSIFFKASSEVVSAME---RMLLLDPDSRVSAAVALELPMFSEFREPEEETEALPYDHSMD-NADLSLEQWKRHTFTEILSFQPPLIEL 356
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: mapk14a (mitogen-activated protein kinase 14a [Source:NCBI gene;Acc:65237]) HSP 1 Score: 312.383 bits (799), Expect = 5.985e-104 Identity = 158/355 (44.51%), Postives = 232/355 (65.35%), Query Frame = 1
Query: 115 VMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQ----FDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
V F +++ + W V RY NL +G G+ GSVCS+ D++ + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ +++ F+D+Y VT L+ DL+ I+ + + ++++ F +YQILRGLKYIHS G+IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D+ +QL +I+Q+ T + ++ ++E +NY ++++ DF F + +DLL +MLVLD +QRI+A +AL+H Y YHD DE PY + E N + +E W+ ++ + +FVP
Sbjct: 5 VKEGFCRQELNKTVWEVPRRYVNLTSVGSGAYGSVCSSLDTKTGMKVAVKKLSRPFQSVIHAKRTYRELRLLKHMKHENVIGLMDVFTPNSSLEEFDDLYLVTDLMGADLNNIVKCQKLTDDHVQFLVYQILRGLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHADDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDRILSDINQLVKILQLTGTPPQYLIDRMQSKEARNY-IQSLPYTQKRDFKDVF--LGANPLVVDLLERMLVLDTDQRITAAEALVHQYFAQYHDPDDEPEAEPYDQSFE-NQEFPVEEWRRLTYEEVISFVP 355
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: mapk12a (mitogen-activated protein kinase 12a [Source:NCBI gene;Acc:30681]) HSP 1 Score: 292.352 bits (747), Expect = 4.219e-96 Identity = 152/340 (44.71%), Postives = 210/340 (61.76%), Query Frame = 1
Query: 121 RKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTE-DLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIET--WK 1131
+ F +I+ W V RY L +G G+ G+VCS+ D VA+KKL PFQS+ AKR YRE+++L HM HENVI L+D+F+ + F D Y V P + DLSKI+ ++ + + IYQIL+GLKYIHS+G+IHRDL P N+AVNED EL+ILDFGL+R D MTGYVV+R+YRAPE+I +YT +D+WS GCIMAEM+ + LF GND DQL I+++ T + ++ E Y ++ LP ++ + + + AIDLL KML LDP QR +A++AL HP+ + +E+ PY T E V++ET WK
Sbjct: 9 KGFYRIEINKMVWEVPKRYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQSRVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQSDDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQEMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKPLFPGNDHMDQLMLILKLTGTPPQYLVDRMDENEAAKY----IKTLPKMEKRRISTVFPNANPIAIDLLEKMLALDPEQRPTASEALQHPFFSETREPLEETEAEPYDQTFEG---VELETSEWK 341
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000729.1 (pep scaffold:Pmarinus_7.0:GL477416:20288:37329:-1 gene:ENSPMAG00000000656.1 transcript:ENSPMAT00000000729.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 258.84 bits (660), Expect = 2.210e-82 Identity = 143/360 (39.72%), Postives = 213/360 (59.17%), Query Frame = 1
Query: 112 KVMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDD--FMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDL-------------KAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYL-DTLESNSDVDIETWKDGIW 1143
K+ +F + ++ S + V+ RY+NLK IG G+QG VC+A+D VAIKKL+ PFQ+Q AKR YRE+ ++ ++H+N+ICL ++F+ + F DVY V L+ +L ++I E + E + + IYQ+L G+K++HS G+IHRDL P NI V D L+ILDFGL+R + MT YVV+RYYRAPE+I YT +D+WS GC++ EM+ HRILF G D DQ +I++ T F ++ +NY VE P + F + + + L +A DLLSKMLV+DP +RI+ AL HPY+ ++D ++ P + D + I+ WK+ I+
Sbjct: 5 KLETQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDIMQNRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIICLFNVFTPQKSLEEFQDVYLVMELMDANLCQVIQME-LDHERMSYLIYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGNSFMMTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCVLGEMIRHRILFPGKDYIDQWNKIIEQLGTPMAEFMKKL-QPTVRNY----VENRPKYAGYSFEKLFPDVLFPADSENNRLKASQARDLLSKMLVIDPAKRINVDQALAHPYINIWYDPSEVEAPPPKIYDKQLDEREHSIDEWKELIY 357
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: mapk1 (mitogen-activated protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-030722-2]) HSP 1 Score: 254.603 bits (649), Expect = 2.102e-81 Identity = 146/349 (41.83%), Postives = 210/349 (60.17%), Query Frame = 1
Query: 163 VVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKD------DFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPP---IDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVG-APYLDTLESNSDVDIETWKDGIWDCMNTFVPKIEN 1179
V RY +L IG G+ G VC+AFD+ + VAIKK+ SPF+ Q +RT RE+KIL HEN+I + D+ +S DVY V L+ DL K++ + + ++IC+F+YQILRGLKYIHS V+HRDL P N+ +N +L+I DFGL+R D F+T YV +R+YRAPEI+ + YT ID+WS GCI+AEML +R LF G DQL I+ I + + I + +NY ++ LPP + +++ F + D KA+DLL KML +P++RI+ +AL HPYLE Y+D +DE V P+ +E + D+ E K+ I++ F P +
Sbjct: 32 VGPRYTSLSYIGEGAYGMVCAAFDNVKLVRVAIKKI-SPFEHQTYCQRTLREIKILLRFKHENIIGINDILRASTID-QMKDVYIVQDLMETDLYKLLKGQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPLFPGKHYLDQLNHILGILGSPSQEDLDCIINMKARNY----LQSLPPKAKVPWNRLFPK--ADSKALDLLDKMLTFNPHRRITVEEALAHPYLEQYYDPSDEPVAEEPFRFDMELD-DLPKERLKEMIFEETARFQPGFQQ 371
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004133.1 (pep scaffold:Pmarinus_7.0:GL479498:22366:34653:-1 gene:ENSPMAG00000003756.1 transcript:ENSPMAT00000004133.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 218.779 bits (556), Expect = 1.247e-67 Identity = 118/287 (41.11%), Postives = 175/287 (60.98%), Query Frame = 1
Query: 223 SAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDD--FMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFF----------RQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFY 1047
+A+D+ VAIKKL+ PFQ+Q AKR +RE+ ++ ++H+N+I L+++FS ++ +F DVY V L+ +L ++I E + E I + +YQ+L G+K++HS G+IHRDL P NI V D L+ILDFGL+R MT YVV+RYYRAPE+I YT +D+WS GCIM EM+ H+ILF G D DQ ++++ T F ++ +NY +ET P F + F + +A DLLS+MLV+DP +RI+ +AL HPY+ +
Sbjct: 1 AAYDTIIDRNVAIKKLSRPFQNQTHAKRAFRELVLMKCVNHKNIIKLLNVFSPQKSQEDFQDVYLVMDLMDANLCQVIRME-LDHERISYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCSLKILDFGLARTAATSFMMTPYVVTRYYRAPEVIL-GMGYTENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPVSEFMKRL-QPTVRNY-VETRPRYPGYSFEKLFPDALFPADSEHSKLKASQARDLLSRMLVIDPLKRITVDEALQHPYIHVW 283
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: HOG1 (Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]) HSP 1 Score: 285.034 bits (728), Expect = 1.455e-92 Identity = 151/339 (44.54%), Postives = 210/339 (61.95%), Query Frame = 1
Query: 124 KFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLP---PIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWK 1131
+F +I + + + +RY +L +G G+ G VCSA D+ VAIKK+ PF + AKRTYRE+K+L H+ HEN+ICL D+F S D+YFVT L DL +++ ++++ + +F+YQILRGLKY+HS GVIHRDL P NI +NE+ +L+I DFGL+R +D MTGYV +RYYRAPEI+ Y ++D+WSAGCI AEM+ + LF G D Q I + + + IC+E L+ V LP PI F + F+ D A+DLL KMLV DP +RI+A DAL HPY YHD TDE V D +++D+ ++TW+
Sbjct: 6 EFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSP-----LEDIYFVTELQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENT----LKFVTSLPHRDPIPFSERFKTVEPD--AVDLLEKMLVFDPKKRITAADALAHPYSAPYHDPTDEPVADAKFDWHFNDADLPVDTWR 333
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: FUS3 (Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]) HSP 1 Score: 227.254 bits (578), Expect = 2.849e-71 Identity = 119/321 (37.07%), Postives = 184/321 (57.32%), Query Frame = 1
Query: 157 WHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDF-------------MTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAP 1080
+++ S ++ ++G G+ G VCSA VAIKK+ PF A RT RE+KIL H HEN+I + ++ + NFN+VY + L+ DL ++I+ + + +++I +FIYQ LR +K +H + VIHRDL P N+ +N + +L++ DFGL+R D+ MT YV +R+YRAPE++ ++ Y+ +D+WS GCI+AE+ + R +F G D QL I I T H + +++++ + P + F + K IDLL +MLV DP +RI+A +AL HPYL+ YHD DE G P
Sbjct: 7 YNISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKI-EPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFE-NFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNP--KGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEP 323
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: SLT2 (Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway [Source:SGD;Acc:S000001072]) HSP 1 Score: 225.328 bits (573), Expect = 4.582e-69 Identity = 130/340 (38.24%), Postives = 199/340 (58.53%), Query Frame = 1
Query: 133 TYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFK--IYVAIKKLASPFQSQDSAKRTYREMKILHHM-DHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKII-AKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSR-------KKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLD-TLESNSDVD 1116
T+K+ D+ V R++ +K IGHG+ G VCSA +E VAIKK+ + F KR+ RE+K+L H H+N+ CL D+ + N +Y L+ D+ +II + + + + + F YQIL GLKYIHS V+HRDL P N+ VN D +L+I DFGL+R + F+T YV +R+YRAPEI+ YT ID+WSAGCI+AE L + +F+G D +QL QI+Q+ T + +I ++ ++Y + + +P + F + + +A+DLL +ML DP +RI+ +AL HPYL +HD DE V + + + ES +D++
Sbjct: 9 TFKVFNQDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDY-IHQLGFIPKVPFVNLYP--NANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADEPVCSEKFEFSFESVNDME 345
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: KSS1 (Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]) HSP 1 Score: 220.705 bits (561), Expect = 1.710e-68 Identity = 130/340 (38.24%), Postives = 196/340 (57.65%), Query Frame = 1
Query: 163 VVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHM-DHENVICLID-LFSSSANRINFNDVYFVTPLLSFDLSKIIAKE-----FMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSR----KKDD------FMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWK 1131
+ S+Y+ + +IG G+ G+VCSA I VAIKK+ PF + RT RE+K+L + +HEN+I ++D + S +++N VY V L+ DL K+I + + ++++ +F YQILR LK IHS VIHRD+ P N+ +N + +L++ DFGL+R D FMT YV +R+YRAPEI+ YT +D+WS GCI+AEM+ + LF G D QL I+++ T + QI ++ K Y + + + PP+ + + + + IDLL KML +P++RISA +AL HPYL YHD +DE P ++D E WK
Sbjct: 9 IPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKI-QPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLN--AVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEY-IANLPMRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPSDEPEYPPL--------NLDDEFWK 336
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Match: KDX1 (Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication [Source:SGD;Acc:S000001644]) HSP 1 Score: 201.445 bits (511), Expect = 1.819e-60 Identity = 117/302 (38.74%), Postives = 173/302 (57.28%), Query Frame = 1
Query: 193 IGHGSQGSVCSAF--DSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHM-DHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKII-AKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLS-------RKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDE 1065
IG GS +CS+ +S + +VAI+K+ + F ++ S KRT RE+K+L H+ H N++ L D N VY L+ DLS+II +++ +++ + FIYQIL LKYIHS V+H DL PKN+ VN D +L+I +FGLS + D F+ GY+ S +Y+APEI+ T +D+WS GCI+AE+L + +F G D D L I+QI T E +I +++ NY + +P F + +A++LL KML DP +RI+ DAL HPYL +HD +E
Sbjct: 29 IGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGN-IPGRSFESILP--GANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEE 327
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO46881 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNM4]) HSP 1 Score: 297.745 bits (761), Expect = 7.947e-98 Identity = 156/332 (46.99%), Postives = 213/332 (64.16%), Query Frame = 1
Query: 157 WHVVSRYENLKIIGHGSQGSVCSAFDSEFKIY-------VAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWK 1131
+ V +Y+ L IG G+ G VCS+ +E VAIKKL+ PFQS AKRTYRE+K+L HM HENVI L+D+F++++ +F DVY VT L+ DL+ I+ + + +E++ F +YQILRGLKYIHS GVIHRDL P NIAVNED EL+ILDFGL+R D MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L + LF GND DQL +IMQ+ + F +I +E +NY + + F ++F + A+DLL KML LD + RI+A +AL HPYL Y D DE + + D+ + ++ IE W+
Sbjct: 18 YEVPRKYQELSPIGTGAYGQVCSSTITEPDPTNPDGPNTVAIKKLSRPFQSTMHAKRTYRELKLLRHMRHENVISLLDVFTTASAFEHFQDVYMVTELMGSDLNGILRFQKLSDEHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELKILDFGLARMTDAEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTSKTLFPGNDHIDQLTKIMQLVGKPSDDFLQKIDSESARNYIAQMPDYR-KTPFDEYF--VGANPLAVDLLEKMLNLDTDHRITAVEALSHPYLASYADPNDEPTCSTFDDSFDEK-ELSIEGWR 345
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO40573 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6R5]) HSP 1 Score: 267.314 bits (682), Expect = 6.840e-86 Identity = 138/317 (43.53%), Postives = 201/317 (63.41%), Query Frame = 1
Query: 163 VVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKII-AKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSR-------KKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLD 1089
V +RY+ ++ IG+G+ G VCSA D+ VA+KK++ F +A+RT+RE+KIL H H+N+IC+ D+ N F+DVY V L+ DL +II + + E++ +F+YQILRGLKYIHS V+HRDL P N+ VNE+ EL+I DFG++R ++ FMT YV +R+YRAPE++ + Y+ IDMWS GCI+AEM+ R LF G + +QL+ I+ + T + F ++ AE K Y L + P+ F +FF + + AI+LLS+ML LDP +RI+ +AL HP+L+ YH E DE LD
Sbjct: 19 VDARYKLIETIGNGAYGVVCSAMDTRTGAKVAVKKISRAFDVLTTARRTHRELKILRHFKHDNIICIRDILKPPVNLDEFDDVYVVLDLMESDLHRIIHTDQPLTTEHVRYFLYQILRGLKYIHSAKVLHRDLKPSNLLVNENAELKIGDFGMARGLCSSPLEQKRFMTEYVATRWYRAPELMLSLNEYSEAIDMWSVGCILAEMIGRRPLFPGANYLNQLQMILSVTGTPSQNFIERMGAERVKTY-LNQLPHKDPVPFEKFFPKAHPE--AINLLSQMLQLDPKERITVENALQHPFLKEYHSEEDEPTCYSPLD 332
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO37435 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFQ0]) HSP 1 Score: 248.825 bits (634), Expect = 3.550e-79 Identity = 129/311 (41.48%), Postives = 187/311 (60.13%), Query Frame = 1
Query: 163 VVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKD------DFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEK-NYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVG 1074
V RY NL IG G+ G V + D+ +AIKK+ SPF+ Q +RT RE+KIL HEN+I ++D+ + + D+Y V PL+ D+ K++ + + ++IC+F+YQILRGLKYIHS V+HRDL P N+ +N +L+I DFGL+R D F+T YV +R+YRAPEI+ + Y+ ID+WS GCI+AEML +R LF G DQL I+ + + +C + EK +L+++ P F + F D KA+DL+ +L +PN+RI+ +AL HPYLE Y+D DE V
Sbjct: 17 VAPRYTNLNYIGEGAYGMVVAGVDNTTGERIAIKKI-SPFEHQTYCQRTLREIKILSRFKHENIIGILDIIRAPRAE-DMKDIYIVQPLMETDMYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYSKAIDIWSVGCILAEMLANRPLFPGKHYLDQLNLILNVLGSPIAD--DLLCIKNEKARSYLQSLPYKPKTPFIKLFSN--ADAKALDLIENLLAFNPNKRITVEEALAHPYLEQYYDPADEPVA 321
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO45525 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSV5]) HSP 1 Score: 204.142 bits (518), Expect = 5.712e-62 Identity = 100/245 (40.82%), Postives = 153/245 (62.45%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDD--FMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQI 855
F T ++ + + V+ RY+NL+ IG G+QG VC+A D+ VAIKKL+ PFQ+ AKR +RE+ ++ ++H+N+I L+++F+ FND+Y V L+ L ++I + + E + + +YQ+L G+K++H +IHRDL P NI V D L+ILDFGL+R MT YVV+RYYRAPE+I Y + +D+WS GCI+AEM+ ++F G D DQ ++ + T E F Q+
Sbjct: 2 FYTAQVGDTIFIVLKRYQNLQPIGSGAQGMVCAAIDTVTGEKVAIKKLSRPFQNVTHAKRAFRELVLMRMVNHKNIIGLLNVFTPDRTLEQFNDLYLVMELMDASLCQVIHMD-LDHERLSYLLYQMLCGVKHLHDADIIHRDLKPSNIVVKSDCSLKILDFGLARTAGSAFMMTPYVVTRYYRAPEVIL-GMGYCDNVDVWSIGCILAEMIRGHVMFPGTDHIDQWNKVTEQLGTPSESFLNQL 244
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Match: EDO30527 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0K0]) HSP 1 Score: 199.519 bits (506), Expect = 2.902e-59 Identity = 112/292 (38.36%), Postives = 174/292 (59.59%), Query Frame = 1
Query: 187 KIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKII-AKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDD----FMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSH-EGFWGQICAEEEKNYFLETVELLPPI-DFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLE 1041
+ IG+G+ G V S D VA+KK+ FQ+ S++R YRE+++L + H+NVI ID+ + F+++Y V+ L+ DL KII + + + +++ F+YQILRGLKY+ S ++HRD+ P N+ VN + L+I DFGL+R ++ MT VV++YYR+PE++ +++YT +D+WS GCI AE+L +ILF+ QL QI+ + T E +E Y L+ P + + Q T + A+ LL +MLV +PN+RIS DAL HPYL+
Sbjct: 43 RPIGYGAFGVVWSVTDPRNGKRVALKKMPKVFQNITSSRRAYRELRMLCTLKHDNVISAIDIVHPGHIDL-FHEIYVVSELMQSDLHKIIVSPQPLTADHVKVFLYQILRGLKYLDSAKILHRDIKPGNLLVNSNCLLKICDFGLARLEEPDESVIMTQEVVTQYYRSPELLTGSTHYTQAVDIWSVGCIFAELLSRKILFQAQSPVQQLNQIIDLLGTPCLEDLSKAGSSEGATKYILQRPHKPPALASLYNLSNQATHE--AVHLLCRMLVFNPNKRISCIDALSHPYLD 331
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14b (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101162042]) HSP 1 Score: 329.717 bits (844), Expect = 4.089e-110 Identity = 163/347 (46.97%), Postives = 234/347 (67.44%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F +++ + W V RY+NL +G G+ GSVCS++D + + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + F+DVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS G++HRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E +NY + ++ +P +F F + A+DLL KMLVLD ++RI+A++AL HPY YHD DE PY + ES +++IE W+ I+D + +F P
Sbjct: 9 FYLQELNKTVWEVPERYQNLSPVGSGAYGSVCSSYDVKTCLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLDEFSDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSAGIVHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPASLISRMPSHEARNY-INSLPHMPKRNFADVF--IGANPLAVDLLEKMLVLDTDKRITASEALAHPYFAQYHDPDDEPEAEPYDQSFESR-ELEIEEWRSLIYDEVLSFEP 351
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14b (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101162042]) HSP 1 Score: 328.946 bits (842), Expect = 8.931e-110 Identity = 164/347 (47.26%), Postives = 232/347 (66.86%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
F +++ + W V RY+NL +G G+ GSVCS++D + + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + F+DVY VT L+ DL+ I+ + + ++++ F IYQILRGLKYIHS G++HRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ IM + T +I +E +NY + ++ +P +F F + A+DLL KMLVLD ++RI+A++AL HPY YHD DE PY + ES +++IE W+ I+D + +F P
Sbjct: 9 FYLQELNKTVWEVPERYQNLSPVGSGAYGSVCSSYDVKTCLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLDEFSDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSAGIVHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMMLVGTPGPELLMKISSEPARNY-INSLPHMPKRNFADVF--IGANPLAVDLLEKMLVLDTDKRITASEALAHPYFAQYHDPDDEPEAEPYDQSFESR-ELEIEEWRSLIYDEVLSFEP 351
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14a (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101160731]) HSP 1 Score: 323.168 bits (827), Expect = 1.312e-107 Identity = 163/352 (46.31%), Postives = 230/352 (65.34%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYT-EDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIEN 1179
F +++ + W V RY+NL +G G+ GSVCSA+D++ + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + F DVYFV L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D +QL+QIM++ T ++ + E + Y + LP + F + + A+DLL KMLVLD ++RI+A +AL HPY YHD DE PY + ES D++I+ WK ++ + +F P + N
Sbjct: 9 FYRQEVNKTIWEVPDRYQNLSPVGSGAYGSVCSAYDTKTGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLKEFTDVYFVNHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAALISRMPSHEARTY----ISSLPHMAKRNFADVFIGANPLAVDLLEKMLVLDTDRRITAAEALEHPYFAQYHDPDDEPEAEPYDQSFESR-DLNIKEWKRLTYEELCSFEPPVFN 355
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk14a (mitogen-activated protein kinase 14A [Source:NCBI gene;Acc:101160731]) HSP 1 Score: 322.013 bits (824), Expect = 4.326e-107 Identity = 164/352 (46.59%), Postives = 228/352 (64.77%), Query Frame = 1
Query: 127 FKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYT-EDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIEN 1179
F +++ + W V RY+NL +G G+ GSVCSA+D++ + VA+KKL+ PFQS AKRTYRE+++L HM HENVI L+D+F+ + + F DVYFV L+ DL+ I+ + + ++++ F IYQILRGLKYIHS +IHRDL P N+AVNED EL+ILDFGL+R DD MTGYV +R+YRAPEI+ +Y +D+WS GCIMAE+L R LF G D DQL+ IM + T +I +E + Y + LP + F + + A+DLL KMLVLD ++RI+A +AL HPY YHD DE PY + ES D++I+ WK ++ + +F P + N
Sbjct: 9 FYRQEVNKTIWEVPDRYQNLSPVGSGAYGSVCSAYDTKTGLKVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLKEFTDVYFVNHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARLTDDEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLIMMLVGTPGPELLMKISSESARTY----ISSLPHMAKRNFADVFIGANPLAVDLLEKMLVLDTDRRITAAEALEHPYFAQYHDPDDEPEAEPYDQSFESR-DLNIKEWKRLTYEELCSFEPPVFN 355
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Match: mapk12a (mitogen-activated protein kinase 12 [Source:NCBI gene;Acc:101159668]) HSP 1 Score: 318.931 bits (816), Expect = 5.411e-106 Identity = 154/353 (43.63%), Postives = 228/353 (64.59%), Query Frame = 1
Query: 109 IKVMRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVP 1167
++V + +++ + W V RY +LK +G G+ G+VCSA DS VAIKKL PFQS+ AKR YRE+++L HM HENVI L+D+F++ + F D Y V P + DL K++ + E+ I + +YQ+L+GLKYIHS G+IHRDL P N+ +N+D EL+ILDFGL+R+ D MTGYVV+R+YRAPE+I +YT +D+WS GCIMAEML + LF+GND DQL +IM+I T F ++ +EE K Y L+++ D + F + D+ A+ ++ KML+LDP +R++A +AL PY + D +E PY +L+ N+++ ++ WK + + TF P
Sbjct: 3 LRVRPGYSRQEVNKTSWEVPDRYRDLKQVGSGAYGTVCSATDSRTGAKVAIKKLYRPFQSEIFAKRAYRELRLLKHMKHENVIGLLDVFTADLSLDRFLDFYLVMPFMGTDLGKLMKMHKLSEDKIQYLVYQMLKGLKYIHSAGIIHRDLKPGNLGINQDCELKILDFGLARQTDSEMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLQGKPLFKGNDHLDQLTEIMKITGTPSPEFLSKLVSEEAKKY-LKSLPKQEKKDLQKVFP--SSDVHAVSMMEKMLLLDPEKRVTAAEALTLPYFTEFRDSEEEKEAQPYDHSLD-NAELSVDQWKRHTFTEILTFKP 351
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000075539.1 (SMESG000075539.1) HSP 1 Score: 740.339 bits (1910), Expect = 0.000e+0 Identity = 354/355 (99.72%), Postives = 355/355 (100.00%), Query Frame = 1
Query: 118 MRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL 1182
MRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSA+RINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL
Sbjct: 1 MRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSADRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL 355
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000075533.1 (SMESG000075533.1) HSP 1 Score: 424.476 bits (1090), Expect = 2.026e-147 Identity = 193/353 (54.67%), Postives = 262/353 (74.22%), Query Frame = 1
Query: 124 KFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL 1182
+F+ + I +SDW V +RYENL IGHG+ GSVC+AFD + + VAIKKLA PF S + AKRTYRE+KI+HHMDHEN++CLID ++ + R +F+DVY +TPL+ DL+ II + + E++ F +YQILRGLKY+HS+ +IHRDL P NIAVNED EL+ILDFGL+R+ D+ MTGYV +R+YRAPEI+ +YTN++D+WS GCIMAE+ + LF GND DQL++IM++A T + F +I +E+ + + E ++ P DF+ FF QYT+D AIDLL +MLVLDP++RISA DAL HPYL YHDE DE ++D +E +DVD+ETWKD +WD + F P+I +L
Sbjct: 4 EFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSL 356
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000075533.1 (SMESG000075533.1) HSP 1 Score: 423.705 bits (1088), Expect = 8.199e-147 Identity = 193/353 (54.67%), Postives = 262/353 (74.22%), Query Frame = 1
Query: 124 KFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDDFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFVPKIENL 1182
+F+ + I +SDW V +RYENL IGHG+ GSVC+AFD + + VAIKKLA PF S + AKRTYRE+KI+HHMDHEN++CLID ++ + R +F+DVY +TPL+ DL+ II + + E++ F +YQILRGLKY+HS+ +IHRDL P NIAVNED EL+ILDFGL+R+ D+ MTGYV +R+YRAPEI+ +YTN++D+WS GCIMAE+ + LF GND DQL++IM++A T + F +I +E+ + + E ++ P DF+ FF QYT+D AIDLL +MLVLDP++RISA DAL HPYL YHDE DE ++D +E +DVD+ETWKD +WD + F P+I +L
Sbjct: 28 EFQLHNIAHSDWTVPTRYENLNPIGHGAYGSVCAAFDHKLQRQVAIKKLARPFHSPEYAKRTYRELKIIHHMDHENIVCLIDAYTPQSTRESFSDVYLITPLMGADLNAIIRTQELLNEHVQFLVYQILRGLKYMHSSEIIHRDLKPSNIAVNEDCELKILDFGLARQTDEEMTGYVATRWYRAPEIMLSWMHYTNRVDIWSVGCIMAELFTRKPLFPGNDHIDQLKKIMELAGTPDKEFMNKIVSEDARAFIREKIQTSPRKDFNSFFWQYTKDENAIDLLDRMLVLDPDRRISAKDALAHPYLADYHDEHDEPTAPLFVDVMEGKTDVDLETWKDTVWDFIQNFTPRISSL 380
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000012868.1 (SMESG000012868.1) HSP 1 Score: 242.276 bits (617), Expect = 3.019e-76 Identity = 131/342 (38.30%), Postives = 206/342 (60.23%), Query Frame = 1
Query: 157 WHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRINFNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKDD------FMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGAPYLDTLESNSDVDIETWKDGIWDCMNTFV 1164
++V SRY NL+ IG G+ G V SA D+ VAIK++ SPF+ Q +RTYRE+KIL H HENVI + +L + ++ + D+Y V L+ D+ K+I + + E+IC+F+YQILRG+KYIHS V+HRDL P N+ VN + +L+I DFGL+R D +T YV +R+YRAPE++ + Y+ +DMWS GCI+AEML + LF G QL+ I + + I E+ +N F+E + +P + + F + +D+L ++L +P++R++A AL HPYL+ Y++ TDE ++ ++ + T K IW+ ++++V
Sbjct: 15 FYVGSRYTNLRFIGEGAYGIVVSATDNVTHEDVAIKRI-SPFEHQTFCQRTYREIKILLHFKHENVIDIKNLLTPASKIEDIKDIYIVQSLMDTDMYKLIKDQKLSNEHICYFLYQILRGVKYIHSANVLHRDLKPSNLLVNSNCDLKICDFGLARVNDPVQDHNGMLTEYVATRWYRAPEVMLNSKGYSKAMDMWSIGCILAEMLGCKPLFPGKHYVQQLKLIFDVLGSPDYEDKSWIVNEKARN-FVEKLIDIPKRPWEELFP--NSEPFCLDILDQLLAFNPSKRLTADKALQHPYLQQYYEPTDEPESDSPFNSEHELDNLSLNTLKQMIWEQVSSYV 352
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Match: SMESG000001435.1 (SMESG000001435.1) HSP 1 Score: 240.35 bits (612), Expect = 7.996e-76 Identity = 135/322 (41.93%), Postives = 193/322 (59.94%), Query Frame = 1
Query: 157 WHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKLASPFQSQDSAKRTYREMKILHHMDHENVICLIDLFSSSANRIN-FNDVYFVTPLLSFDLSKIIAKEFMKEENICFFIYQILRGLKYIHSTGVIHRDLAPKNIAVNEDNELRILDFGLSRKKD------DFMTGYVVSRYYRAPEIIFKNSNYTNKIDMWSAGCIMAEMLIHRILFRGNDQFDQLRQIMQIADTSHEGFWGQICAEEEKNYFLETVELLPPIDFHQFFRQYTEDLKAIDLLSKMLVLDPNQRISATDALLHPYLEFYHDETDESVGA-PYLDTLE 1098
+ V RY +L IG G+ G V SA+D+ K VAIKK+ SPF+ Q +RT RE+KIL HEN+I + D+ + AN IN DVY V L+ DL K++ + + ++ C+F+YQILRGLKYIHS V+HRDL P N+ +N +L+I DFGL+R D +T YV +R+YRAPEI+ + YT ID+WS GCI+AEML ++ LF G DQL I+ + + ++ I + + Y L+ + P + + + D +A+DL+ K+L +P RI DAL HPYL+ Y+D DE V A P+ + LE
Sbjct: 13 FEVKPRYIDLNYIGEGAYGMVASAYDNIKKEKVAIKKI-SPFEYQTYCQRTLREIKILTRFKHENIIDIRDIIT--ANSINEMKDVYIVQCLMETDLFKLLKTQQLSNDHTCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPEHDHTGLLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLNNKPLFPGKHYIDQLNLILGVLGSPNQEDLDSIVNLKARGY-LQQLPYKPKVSWKSLYP--NADDQALDLIEKLLTFNPVNRIGVEDALAHPYLKQYYDPADEPVAAKPFTNDLE 328 The following BLAST results are available for this feature:
BLAST of Mitogen-activated protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Mitogen-activated protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024187 ID=SMED30024187|Name=Mitogen-activated protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1324bpback to top protein sequence of SMED30024187-orf-1 >SMED30024187-orf-1 ID=SMED30024187-orf-1|Name=SMED30024187-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=356bp MRKFKTYKIHYSDWHVVSRYENLKIIGHGSQGSVCSAFDSEFKIYVAIKKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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