PRELI domain-containing protein 1

Overview


Name	PRELI domain-containing protein 1
Smed ID	SMED30024181
Length (bp)	940

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of PRELI domain-containing protein 1 (SMED30024181) t-SNE clustered cells

Violin plots show distribution of expression levels for PRELI domain-containing protein 1 (SMED30024181) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PRELI domain-containing protein 1 (SMED30024181) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PRELI domain-containing protein 1 (SMED30024181) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30024181

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30024181	h1SMcG0012936	Contig1324	GPL15192	PMID:23079596 Forsthoefel et al., 2012
posterior side	SMED30024181	h1SMcG0012936	dd_Smed_v4_3507_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior muscle cell	SMED30024181	h1SMcG0012936	dd_Smed_v4_3507_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Human
Match: PRELID1 (PRELI domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30255])

HSP 1 Score: 111.694 bits (278), Expect = 5.728e-29
Identity = 59/170 (34.71%), Postives = 99/170 (58.24%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +   + L  +W+ V + FW+RYPNPY+KHVL+EDI+HRE+ PD  L ++RL TK +   +P   + LF     +  ++LE+SI+ P+ Q M T T+N+  ++   ++ E+C Y   S     T I +  W+ S +    SR V +  + ++KS   K+  G+E+++
Sbjct:    1 MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTPDQKLLSRRLLTKTN--RMPRWAERLFPANVAHSVYVLEDSIVDPQNQTMTTFTWNINHAR-LMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFG-VSRAVQEFGLARFKSNVTKTMKGFEYIL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Human
Match: PRELID1 (PRELI domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30255])

HSP 1 Score: 111.309 bits (277), Expect = 1.041e-28
Identity = 59/170 (34.71%), Postives = 99/170 (58.24%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +   + L  +W+ V + FW+RYPNPY+KHVL+EDI+HRE+ PD  L ++RL TK +   +P   + LF     +  ++LE+SI+ P+ Q M T T+N+  ++   ++ E+C Y   S     T I +  W+ S +    SR V +  + ++KS   K+  G+E+++
Sbjct:    1 MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTPDQKLLSRRLLTKTN--RMPRWAERLFPANVAHSVYVLEDSIVDPQNQTMTTFTWNINHAR-LMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFG-VSRAVQEFGLARFKSNVTKTMKGFEYIL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Human
Match: PRELID1 (PRELI domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30255])

HSP 1 Score: 91.6633 bits (226), Expect = 1.566e-22
Identity = 43/106 (40.57%), Postives = 68/106 (64.15%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESK 422
            M K +   + L  +W+ V + FW+RYPNPY+KHVL+EDI+HRE+ PD  L ++RL TK +   +P   + LF     +  ++LE+SI+ P+ Q M T T+N+  ++
Sbjct:    1 MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTPDQKLLSRRLLTKTN--RMPRWAERLFPANVAHSVYVLEDSIVDPQNQTMTTFTWNINHAR 104

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Human
Match: PRELID3B (PRELI domain containing 3B [Source:HGNC Symbol;Acc:HGNC:15892])

HSP 1 Score: 54.6842 bits (130), Expect = 2.468e-8
Identity = 32/128 (25.00%), Postives = 64/128 (50.00%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF---KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            K + +    ++ W  V +   ++YPNP    V+  D++ R I P G L++ RL + +    LP  +K L    + K ++ E S++ P ++ M+  + N+  + N   + E+  Y P    P++T + +
Sbjct:    2 KIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHIDPSGKLHSHRLLSTEW--GLPSIVKSLIGAARTKTYVQEHSVVDPVEKTMELKSTNISFT-NMVSVDERLIYKPHPQDPEKTVLTQ 126

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Human
Match: PRELID3A (PRELI domain containing 3A [Source:HGNC Symbol;Acc:HGNC:24639])

HSP 1 Score: 51.9878 bits (123), Expect = 1.650e-7
Identity = 32/127 (25.20%), Postives = 61/127 (48.03%), Query Frame = 3

Query:  120 TKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKR-LTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            TK    +   ++ W+ V     ++YPNP    VL  D++ R +   G L++ R L+T+    +L   I    +   +I E S++ P ++ M+  + N+  + N   + E+  YTP    P+ T + +
Sbjct:   22 TKGLPGAEACSHPWDTVIQAAMRKYPNPMNPSVLGVDVLQRRVDGRGRLHSLRLLSTEWGLPSLVRAILGTSRTLTYIREHSVVDPVEKKMELCSTNITLT-NLVSVNERLVYTPHPENPEMTVLTQ 147

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Celegans
Match: B0334.4 (pep chromosome:WBcel235:II:11495692:11496663:1 gene:WBGene00007144.1 transcript:B0334.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:B0334.4)

HSP 1 Score: 62.7734 bits (151), Expect = 2.108e-11
Identity = 37/119 (31.09%), Postives = 65/119 (54.62%), Query Frame = 3

Query:  138 STYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEF----ILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQ 482
            +T   Y+++ VAS FW RYPN +AKH++SED++ R+I  D ++ TK+L  K+    L    +++ +  +     ++EES+     + + T T NV     +  L+E+C Y  +    Q 
Sbjct:    8 NTSFPYSFDEVASAFWDRYPNSHAKHIISEDVLERQI-TDNTIVTKKLIVKQGSSILKRVPRWISRMTDIQVVPVIEESVYDKVSKKLVTYTRNVSHISLFQ-LHERCIYKSSEDNQQH 124

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Celegans
Match: F15D3.6 (pep chromosome:WBcel235:I:11572121:11577488:-1 gene:WBGene00008856.1 transcript:F15D3.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F15D3.6)

HSP 1 Score: 48.9062 bits (115), Expect = 9.635e-7
Identity = 38/159 (23.90%), Postives = 75/159 (47.17%), Query Frame = 3

Query:  147 LNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYL-FKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKN 620
             ++ W  VA   +++YPNP  + +   D++ ++ L  G + T+R+  + HF    +  K   F   ++  E ++I P ++     T N+  S ++  + EK +YTP    P +T + + + +   + A F+    K  +  Y   + K   G E VI +
Sbjct:   10 FDHEWETVAQAAFRKYPNPLNRSITGIDVV-KQTLEAGKILTERI-IQSHFSIPSWATKLTGFSGTQYSHEYTVIDPTRKEFSLTTRNLNGS-SFLRVDEKLTYTPAHEDPNKTILKQDVIVTITLPA-FADYCEKTFLSIYSQNANKGRQGVEWVIDH 164

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Fly
Match: prel (gene:FBgn0033413 transcript:FBtr0333003)

HSP 1 Score: 74.3294 bits (181), Expect = 2.752e-15
Identity = 50/167 (29.94%), Postives = 90/167 (53.89%), Query Frame = 3

Query:  132 KTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEF-ILEESIISPRKQLMDTLTYNVGESK----NYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIK 617
            +T T  +Y+W  V   +W RYPNP + HVL+ED I RE+  DG L+++RL +K +   +P      + N    I+E+S++ P K+   T T N+G +K    +  ++Y +     T +V       +  +I S++   FSR +    + ++K+   K+S G+ +V++
Sbjct:    9 RTETVFDYSWMNVVVAYWNRYPNPSSTHVLTEDTIQREVR-DGKLFSRRLLSKTN--PVPKWGARFYNNVPVKIVEDSVLDPVKKTFTTFTRNLGMTKIMKVDEIVVYSEQKDGSTLAV-------RRAYISSQVFG-FSRAIRAFGIERFKANGNKASNGFNYVLR 164

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Fly
Match: prel (gene:FBgn0033413 transcript:FBtr0300293)

HSP 1 Score: 74.3294 bits (181), Expect = 2.752e-15
Identity = 50/167 (29.94%), Postives = 90/167 (53.89%), Query Frame = 3

Query:  132 KTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEF-ILEESIISPRKQLMDTLTYNVGESK----NYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIK 617
            +T T  +Y+W  V   +W RYPNP + HVL+ED I RE+  DG L+++RL +K +   +P      + N    I+E+S++ P K+   T T N+G +K    +  ++Y +     T +V       +  +I S++   FSR +    + ++K+   K+S G+ +V++
Sbjct:    9 RTETVFDYSWMNVVVAYWNRYPNPSSTHVLTEDTIQREVR-DGKLFSRRLLSKTN--PVPKWGARFYNNVPVKIVEDSVLDPVKKTFTTFTRNLGMTKIMKVDEIVVYSEQKDGSTLAV-------RRAYISSQVFG-FSRAIRAFGIERFKANGNKASNGFNYVLR 164

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Fly
Match: slmo (gene:FBgn0029161 transcript:FBtr0299810)

HSP 1 Score: 50.8322 bits (120), Expect = 3.530e-7
Identity = 35/130 (26.92%), Postives = 58/130 (44.62%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHF-----KALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            K + +    N+ W  V    W++YPNP    ++  D++ R ++ DG L+T RL   K +      AL  T K  F +     E S + P ++ M   T N+   +N  +  E   Y P  S   +T + +
Sbjct:    2 KIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRVV-DGVLHTHRLVQSKWYFPKWTHALIGTAKTCFAS-----ERSTVDPERKQMVLKTNNLTFCRNISV-DEVLYYEPHPSDASKTLLKQ 124

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Fly
Match: slmo (gene:FBgn0029161 transcript:FBtr0343130)

HSP 1 Score: 50.8322 bits (120), Expect = 3.530e-7
Identity = 35/130 (26.92%), Postives = 58/130 (44.62%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHF-----KALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            K + +    N+ W  V    W++YPNP    ++  D++ R ++ DG L+T RL   K +      AL  T K  F +     E S + P ++ M   T N+   +N  +  E   Y P  S   +T + +
Sbjct:    2 KIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRVV-DGVLHTHRLVQSKWYFPKWTHALIGTAKTCFAS-----ERSTVDPERKQMVLKTNNLTFCRNISV-DEVLYYEPHPSDASKTLLKQ 124

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Fly
Match: slmo (gene:FBgn0029161 transcript:FBtr0112945)

HSP 1 Score: 50.8322 bits (120), Expect = 3.530e-7
Identity = 35/130 (26.92%), Postives = 58/130 (44.62%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHF-----KALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            K + +    N+ W  V    W++YPNP    ++  D++ R ++ DG L+T RL   K +      AL  T K  F +     E S + P ++ M   T N+   +N  +  E   Y P  S   +T + +
Sbjct:    2 KIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRVV-DGVLHTHRLVQSKWYFPKWTHALIGTAKTCFAS-----ERSTVDPERKQMVLKTNNLTFCRNISV-DEVLYYEPHPSDASKTLLKQ 124

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Zebrafish
Match: prelid1a (PRELI domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-040426-1341])

HSP 1 Score: 108.997 bits (271), Expect = 4.831e-28
Identity = 59/169 (34.91%), Postives = 98/169 (57.99%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYL---FKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +    +L  +W+ V+S FW+RYPNPY+ HVL+EDII RE+ PD  L ++RL TK   +A  +  K+L      K +I+E+S++ P+ + + TLT+N+  ++   I  E+C Y         T I +  WI SK+    SR + +  + ++KS   K+  G+E+++
Sbjct:    1 MVKYFSCVGFLKSSWDQVSSAFWQRYPNPYSNHVLTEDIIFREVTPDNCLKSRRLLTKTS-RAPRWAEKFLPAHMAQKAYIIEDSVVDPQGKTLTTLTWNISHARVMSI-EERCVYKVNPENSSWTEIERQAWISSKLYG-LSRAIQEFGLARFKSNVTKTMKGFEYIL 166

[Close]

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYL---FKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +    +L  +W+ V+S FW+RYPNPY+ HVL+EDII RE+ PD  L ++RL TK   +A  +  K+L      K +I+E+S++ P+ + + TLT+N+  ++   I  E+C Y         T I +  WI SK+    SR + +  + ++KS   K+  G+E+++
Sbjct:    1 MVKYFSCVGFLKSSWDQVSSAFWQRYPNPYSNHVLTEDIIFREVTPDNCLKSRRLLTKTS-RAPRWAEKFLPAHMAQKAYIIEDSVVDPQGKTLTTLTWNISHARVMSI-EERCVYKVNPENSSWTEIERQAWISSKLYG-LSRAIQEFGLARFKSNVTKTMKGFEYIL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Zebrafish
Match: prelid1b (PRELI domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-050522-169])

HSP 1 Score: 101.679 bits (252), Expect = 2.078e-25
Identity = 53/170 (31.18%), Postives = 99/170 (58.24%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKE--FILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKN 620
            M K + + T +  +W++V + FW+RYPNP++ HVL+ED++ R++  +  L ++RL TK +   LP   + +F  +   +I+E+S++    + + T+T+NV  +K   ++ E+C +T     P  T I +  WI S +    SRP+ +  + +++S  +K+  G EH I N
Sbjct:    1 MGKYFFSETEIKNSWDLVLTAFWQRYPNPFSSHVLTEDVLFRKVTSENLLVSRRLFTKTN--RLPRWAERIFPGRRSVYIIEDSVVDLSNRSLTTMTWNVNHAKLMRVV-ERCVFTGEQDRPVWTHITRQAWISSGVFG-LSRPIQEFGLARFRSNQLKAMKGLEHAISN 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Zebrafish
Match: prelid3b (PRELI domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-031002-13])

HSP 1 Score: 53.5286 bits (127), Expect = 3.942e-8
Identity = 47/186 (25.27%), Postives = 84/186 (45.16%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKE---FILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSV-KSSIGYEHVIKNNLLLNVPINSKFIPAR 668
            K + +    N+ W  V     ++YPNP    V   D++ R +   G L++KRL + +    LP  ++ L  N     +I E+S++ P+++  +  + N+  + N   + E+  Y P    P++T + +   I  K  +  S   ++ LM    ST+  K     E VI+    LN  I    + AR
Sbjct:    2 KIWTSEHIFNHPWETVTKAAMQKYPNPMNPSVFGVDVLDRNVDQQGRLHSKRLLSTEW--GLPSIVRSLIGNTRTCTYIQEQSVVDPKEKTFELQSTNITFT-NMVSVDERLIYRPHPEDPEKTMLTQEAIISVKGVSLSS--YLEGLMASTISTNAGKGREAMEWVIRR---LNTEIEELAMTAR 179

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Zebrafish
Match: prelid3a (PRELI domain containing 3A [Source:ZFIN;Acc:ZDB-GENE-130530-654])

HSP 1 Score: 48.9062 bits (115), Expect = 1.276e-6
Identity = 31/128 (24.22%), Postives = 60/128 (46.88%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF---KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            K + T    +Y W  V     ++YPNP    V+  D++ R +   G L++ RL + +    LP  +K +    +   ++ E SI+ P ++ M+  + N+  + N   + E+  Y P    P+ T + +
Sbjct:    2 KIWSTEHIFSYPWETVIKAAMRKYPNPMNPSVVGVDVLDRNLDTHGRLHSHRLLSTEW--GLPGVVKAILGTSRTVTYVKEHSIVDPEEKKMELCSTNITLT-NLISVDERLVYRPHPDNPEVTVLTQ 126

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Xenopus
Match: jak3 (Janus kinase 3 (a protein tyrosine kinase, leukocyte) [Source:Xenbase;Acc:XB-GENE-5904698])

HSP 1 Score: 102.064 bits (253), Expect = 2.893e-25
Identity = 60/179 (33.52%), Postives = 100/179 (55.87%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVP 641
            M K +     L  +W+ V++ FW+RYPNPY+KHVLSEDI++RE+ PD  L T+RL TK +   LP   + +F     +  +++E+SII P  + M T T+N+  +    +  E+C Y   S     T I +  W+ SK+    +R + +  + ++KS   K+  G+E ++   +  +VP
Sbjct:    1 MVKYFSGFNILKNSWDQVSAAFWQRYPNPYSKHVLSEDILYREVTPDHKLLTRRLLTKTN--RLPRWAERIFPANVAHAVYVVEDSIIDPFSKTMTTYTWNINHASIMSV-EERCVYCENSENSNWTEIKREAWVSSKVFG-LTRAIQEFGLARFKSNVTKAMKGFEFIL-GKMQGDVP 174

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Xenopus
Match: lcat (lecithin-cholesterol acyltransferase [Source:Xenbase;Acc:XB-GENE-980396])

HSP 1 Score: 50.8322 bits (120), Expect = 3.650e-7
Identity = 29/128 (22.66%), Postives = 62/128 (48.44%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKE---FILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            + + +    ++ W+ V     ++YPNP    V+  D++ R + P G L+++RL   +    LP  ++ +        +I E S++ P ++ M   + N+  + N   + E+  YTP    P++T + +
Sbjct:    2 RIWSSEHVFSHPWDTVIKAAMRKYPNPMNPCVVGVDVVDRNLDPQGRLHSQRLLCTEW--GLPSLVRAILGTNRTLTYIKEHSVVDPIEKKMVLCSTNISLT-NLVSVDERLVYTPHPENPEETVLTQ 126

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Xenopus
Match: lcat (lecithin-cholesterol acyltransferase [Source:Xenbase;Acc:XB-GENE-980396])

HSP 1 Score: 50.447 bits (119), Expect = 4.918e-7
Identity = 30/123 (24.39%), Postives = 60/123 (48.78%), Query Frame = 3

Query:  138 STYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKE---FILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            S +  + W+ V     ++YPNP    V+  D++ R + P G L+++RL   +    LP  ++ +        +I E S++ P ++ M   + N+  + N   + E+  YTP    P++T + +
Sbjct:    2 SVWSVHPWDTVIKAAMRKYPNPMNPCVVGVDVVDRNLDPQGRLHSQRLLCTEW--GLPSLVRAILGTNRTLTYIKEHSVVDPIEKKMVLCSTNISLT-NLVSVDERLVYTPHPENPEETVLTQ 121

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Xenopus
Match: lcat (lecithin-cholesterol acyltransferase [Source:Xenbase;Acc:XB-GENE-980396])

HSP 1 Score: 50.0618 bits (118), Expect = 1.236e-6
Identity = 29/118 (24.58%), Postives = 58/118 (49.15%), Query Frame = 3

Query:  153 YTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKE---FILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            + W+ V     ++YPNP    V+  D++ R + P G L+++RL   +    LP  ++ +        +I E S++ P ++ M   + N+  + N   + E+  YTP    P++T + +
Sbjct:   77 HPWDTVIKAAMRKYPNPMNPCVVGVDVVDRNLDPQGRLHSQRLLCTEW--GLPSLVRAILGTNRTLTYIKEHSVVDPIEKKMVLCSTNISLT-NLVSVDERLVYTPHPENPEETVLTQ 191

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Mouse
Match: Prelid1 (PRELI domain containing 1 [Source:MGI Symbol;Acc:MGI:1913744])

HSP 1 Score: 112.079 bits (279), Expect = 4.159e-29
Identity = 60/170 (35.29%), Postives = 99/170 (58.24%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +   + L  +W+ V + FW+RYPNPY+KHVL+EDI+HRE+ PD  L ++RL TK +   +P   + LF     +  +ILE+SI+ P+ Q M T T+N+  ++   ++ E+C Y   S     T I +  W+ S +    SR V +  + ++KS   K+  G+E+++
Sbjct:    1 MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTPDQKLLSRRLLTKTN--RMPRWAERLFPANVAHSVYILEDSIVDPQNQTMTTFTWNINHAR-LMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFG-VSRAVQEFGLARFKSNVTKTMKGFEYIL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Mouse
Match: Prelid3b (PRELI domain containing 3B [Source:MGI Symbol;Acc:MGI:1913640])

HSP 1 Score: 54.299 bits (129), Expect = 2.180e-8
Identity = 31/128 (24.22%), Postives = 64/128 (50.00%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF---KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            K + +    ++ W  V +   ++YPNP    V+  D++ R + P G L++ RL + +    LP  +K L    + K ++ E S++ P  + M+  + N+  + N   + E+ +Y P    P++T + +
Sbjct:    2 KIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHVDPSGKLHSHRLLSTEW--GLPSIVKSLIGAARTKTYVQEHSVVDPVTRTMELKSTNISFT-NMVSVDERLTYKPHLQDPEKTVLTQ 126

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Mouse
Match: Prelid3a (PRELI domain containing 3A [Source:MGI Symbol;Acc:MGI:2442865])

HSP 1 Score: 47.7506 bits (112), Expect = 3.024e-6
Identity = 30/126 (23.81%), Postives = 59/126 (46.83%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKR-LTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINK 497
            K + +     + W+ V     ++YPNP    V+  D++ R +   G L++ R L+T+     L   I    +   +I E S++ P  + M+  + N+  + N   + E+  YTP    P++T + +
Sbjct:    2 KIWSSEHVFGHPWDTVIKAAMRKYPNPMNPCVVGVDVLERSVDGCGRLHSLRLLSTEWGLPGLVRAILGANRTLTYIKERSVVDPAARKMELCSTNITLT-NLVSVNERLVYTPHPENPEKTVLTQ 126

[Close]

BLAST of PRELI domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q8R107|PRLD1_MOUSE (PRELI domain-containing protein 1, mitochondrial OS=Mus musculus OX=10090 GN=Prelid1 PE=1 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 2.909e-28
Identity = 60/170 (35.29%), Postives = 99/170 (58.24%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +   + L  +W+ V + FW+RYPNPY+KHVL+EDI+HRE+ PD  L ++RL TK +   +P   + LF     +  +ILE+SI+ P+ Q M T T+N+  ++   ++ E+C Y   S     T I +  W+ S +    SR V +  + ++KS   K+  G+E+++
Sbjct:    1 MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTPDQKLLSRRLLTKTN--RMPRWAERLFPANVAHSVYILEDSIVDPQNQTMTTFTWNINHAR-LMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFG-VSRAVQEFGLARFKSNVTKTMKGFEYIL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9Y255|PRLD1_HUMAN (PRELI domain-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PRELID1 PE=1 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 4.998e-28
Identity = 59/170 (34.71%), Postives = 99/170 (58.24%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +   + L  +W+ V + FW+RYPNPY+KHVL+EDI+HRE+ PD  L ++RL TK +   +P   + LF     +  ++LE+SI+ P+ Q M T T+N+  ++   ++ E+C Y   S     T I +  W+ S +    SR V +  + ++KS   K+  G+E+++
Sbjct:    1 MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTPDQKLLSRRLLTKTN--RMPRWAERLFPANVAHSVYVLEDSIVDPQNQTMTTFTWNINHAR-LMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFG-VSRAVQEFGLARFKSNVTKTMKGFEYIL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q32KN9|PRLD1_BOVIN (PRELI domain-containing protein 1, mitochondrial OS=Bos taurus OX=9913 GN=PRELID1 PE=2 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 6.081e-27
Identity = 59/170 (34.71%), Postives = 98/170 (57.65%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +   + L  +W+ V + FW+RYPNPY+KHVL+EDI+HRE+  D  L ++RL TK +   +P   + LF     +  +ILE+SI+ P+ Q M T T+N+  ++   ++ E+C Y   S     T I +  W+ S +    SR V +  + ++KS   K+  G+E+++
Sbjct:    1 MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTSDQKLLSRRLLTKTN--RMPRWAERLFPANVAHSVYILEDSIVDPQNQTMTTFTWNINHAR-LMVVEERCVYRVNSDNSGWTEIRREAWVSSSLFG-VSRAVQEFGLARFKSNVTKTMKGFEYIL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q90673|PRLD1_CHICK (PRELI domain-containing protein 1, mitochondrial OS=Gallus gallus OX=9031 GN=PRELID1 PE=2 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 9.189e-24
Identity = 54/160 (33.75%), Postives = 91/160 (56.88%), Query Frame = 3

Query:  147 LNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            L   W+ V + FW+RYPNPY+KHVL+EDI+HRE+  D  L ++RL TK +   +P   +  F     +  +I+E+SI+ P+ + M T T+N+  ++   +  E+C Y         T + +  W+ S +    SR V +  + ++KS   KS+ G+E+V+
Sbjct:   11 LKGPWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTADHKLLSRRLLTKTN--RMPRWAERFFPANVAHNVYIVEDSIVDPKNRTMTTFTWNINHARLMAV-EERCVYRVNPENSSWTEVKREAWVSSSLFG-VSRAVQEFGLARFKSNVTKSTKGFEYVL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9UT07|UPS1_SCHPO (Protein ups1 homolog OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAP8A3.10 PE=3 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 3.188e-17
Identity = 54/169 (31.95%), Postives = 87/169 (51.48%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALP-FTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKN 620
            MT      T LN +WN V+S +  RYPNPY+ HV+S D++ R +  +G LYT+RL  K+    LP +    L  NK +ILE S+I P KQ + + T+N+   K   ++ E   +  +S    +T ++ +    S +     R V K  + +++     S  G  +VI+ 
Sbjct:    1 MTAICTDKTELNASWNTVSSAWLTRYPNPYSLHVVSADVLERYVDDEGRLYTERLLVKQG--RLPRWASDLLNVNKSYILERSVIDPSKQELKSETFNLDHVKILRVI-EYSRFIQSSENCSKTIVDTIAKFVSPLRFGLGRRVQKYSLKRFQEQLSSSRRGLLYVIQQ 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. TrEMBL
Match: A0A4S2LFP5 (PRELI/MSF1 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007490 PE=4 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 1.381e-37
Identity = 65/158 (41.14%), Postives = 100/158 (63.29%), Query Frame = 3

Query:  147 LNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALP-FTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIK 617
            LNY W  VAS FW RYPNPY+KHVL+ED++ R +LP   LYTKRL  K+     P +  +++   +E I+EES++  R + +D +T NVG    Y  + E C+Y P+ SVP  T +++ + I+S +NA     ++  L+ +Y+S+S  S +G+E+V K
Sbjct:   10 LNYPWEYVASLFWHRYPNPYSKHVLTEDVVERRVLPGRKLYTKRLIIKQGLGKFPDWLRRFISGARELIVEESVMDMRSKRIDVITRNVGSLGKYATVIESCAYNPSPSVPGTTLVSRNVSIQSNLNAVLRSALVTFLISRYRSSSKASFLGFEYVCK 167

[Close]

BLAST of PRELI domain-containing protein 1 vs. TrEMBL
Match: A0A1S8WL23 (PRELI-like family protein OS=Opisthorchis viverrini OX=6198 GN=X801_09169 PE=4 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 1.009e-34
Identity = 63/158 (39.87%), Postives = 98/158 (62.03%), Query Frame = 3

Query:  147 LNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALP-FTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIK 617
            L+Y W  VAS FW RYPNPY+ HVL+ED++ R +LP   LYTKRL  K+     P +  +++   +E I+EES++  R + +D +T NVG    Y  + E C+Y P+ SVP  T I + + I+S +NA     ++  L+ +Y+S+S  S +G+E++ K
Sbjct:   10 LHYPWEYVASLFWHRYPNPYSTHVLTEDVVERRVLPGRKLYTKRLVIKQGLGKFPDWLRRFISGARELIVEESVMDMRSKRIDVITRNVGSLGKYATVVESCAYNPSPSVPGTTLIKRNVSIQSNLNAVLRPALVTFLISRYRSSSKASFLGFEYICK 167

[Close]

BLAST of PRELI domain-containing protein 1 vs. TrEMBL
Match: A0A4E0S280 (PRELI domain-containing protein 1 mitochondrial OS=Fasciola hepatica OX=6192 GN=D915_001864 PE=4 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 2.452e-33
Identity = 62/156 (39.74%), Postives = 96/156 (61.54%), Query Frame = 3

Query:  147 LNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIK-YLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHV 611
            L + W+ V S FW+RYPNP++KHVL+ED++ R I+P   LYTKRL  K+     P  ++ +L   +E ++EES++  R + +D +T NVG    Y  + E CSYT  S     T I++ + +ESK+N     P+   L ++Y+S+S  S +GYE+V
Sbjct:   10 LGFPWDYVVSLFWERYPNPHSKHVLTEDVLERRIVPGRRLYTKRLIMKQGLGKFPGWLRRFLSGARELVIEESVLDMRSRQLDVVTRNVGSLGKYATVTEYCSYTAKSGSADITTISRALTVESKLNPALRSPLTYFLTHRYQSSSKSSLLGYEYV 165

[Close]

BLAST of PRELI domain-containing protein 1 vs. TrEMBL
Match: A0A504YUG6 (PRELI domain-containing protein 1 mitochondrial OS=Fasciola gigantica OX=46835 GN=FGIG_03696 PE=4 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 2.478e-33
Identity = 62/156 (39.74%), Postives = 96/156 (61.54%), Query Frame = 3

Query:  147 LNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIK-YLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHV 611
            L + W+ V S FW+RYPNP++KHVL+ED++ R I+P   LYTKRL  K+     P  ++ +L   +E ++EES++  R + +D +T NVG    Y  + E CSYT  S     T I++ + +ESK+N     P+   L ++Y+S+S  S +GYE+V
Sbjct:   10 LGFPWDYVVSLFWERYPNPHSKHVLTEDVLERRIVPGRRLYTKRLIMKQGLGKFPGWLRRFLSGARELVIEESVLDMRSRQLDVVTRNVGSLGKYATVTEYCSYTAKSGSADITTISRALTVESKLNPALRSPLTYFLTHRYQSSSKSSLLGYEYV 165

[Close]

BLAST of PRELI domain-containing protein 1 vs. TrEMBL
Match: A0A5J4NS29 (PRELI/MSF1 domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0004366 PE=4 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 2.275e-31
Identity = 64/156 (41.03%), Postives = 102/156 (65.38%), Query Frame = 3

Query:  147 LNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTI-KYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHV 611
            L +TW+ VAS FW RYPNP++KHVL+ED++ R ILP+  LYTKRL  K+     P  + ++L   +E ++EESI+  R++ ++ +T N+G    Y  + E C+YTP ++VP  T I + ++IES +++    P+   L ++Y+ST+  S  GYE+V
Sbjct:   10 LGFTWDYVASLFWHRYPNPFSKHVLTEDVLERRILPNARLYTKRLLLKQGLGKFPVWLQRFLSGTRELVIEESIMDMREKRVEIVTRNIGSLGKYATVIEYCAYTPGTTVPPTTLITRSLFIESNLSSTIRSPLTYFLSHRYRSTAKASLSGYEYV 165

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Cavefish
Match: prelid1a (PRELI domain containing 1 [Source:NCBI gene;Acc:103036730])

HSP 1 Score: 107.071 bits (266), Expect = 2.157e-27
Identity = 59/169 (34.91%), Postives = 96/169 (56.80%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYL---FKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +    +L  TW+ V + FW+RYPNPY+ HVL+EDI+ RE+ PD  L ++RL TK   +A  +  K+L      K +I+E+S++ P  + M TLT+N+  ++   +  E+C Y         T I +  WI S +    SR V +  + ++KS+  K+  G+E+V+
Sbjct:    1 MVKYFSCVGFLKGTWDQVFAAFWQRYPNPYSNHVLTEDIVFREVTPDNRLLSRRLLTKTS-RAPRWAEKFLPSHMARKAYIIEDSVVDPNNRTMVTLTWNISHARVMSV-EERCVYRVNPDNSNWTEIKREAWISSSLYG-LSRAVQEFGLARFKSSVTKTMKGFEYVL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Cavefish
Match: prelid1b (PRELI domain-containing protein 1, mitochondrial-like [Source:NCBI gene;Acc:103043151])

HSP 1 Score: 102.064 bits (253), Expect = 1.342e-25
Identity = 56/170 (32.94%), Postives = 93/170 (54.71%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNK----EFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +   T +   W  V + FW+RYPNPY+ HVL+ED++ RE+ PD  L ++RL TK +   LP   + +F        +I+E+SI+ P  + + TLT+N+  S    ++ E+C +      P  T + +  WI S +    SRP+ +  + ++KS  +K+  G EH +
Sbjct:    1 MGKYFFNETDIRSAWENVLTAFWQRYPNPYSTHVLTEDVVFREVTPDNCLLSRRLLTKTN--RLPRWAERIFPGNLARSVYIVEDSIVDPNNRRLTTLTWNLNHSTLMTVV-ERCVFHGERDRPVWTRLTREAWISSGVFG-LSRPIQEFGLSRFKSNQIKAMKGLEHAL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Cavefish
Match: ENSAMXT00000038061.1 (pep primary_assembly:Astyanax_mexicanus-2.0:4:24625387:24630498:1 gene:ENSAMXG00000031588.1 transcript:ENSAMXT00000038061.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.0182 bits (175), Expect = 4.629e-15
Identity = 34/90 (37.78%), Postives = 57/90 (63.33%), Query Frame = 3

Query:  156 TWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKN--KEFILEESIISPRKQLMDTLTYNVGES 419
            TWN V++ FW++YPNPY+ +VL+ED+I RE+ PD  L ++RL TK     +P   +  F +    +++E+S++ P  + M T T N+  +
Sbjct:   14 TWNQVSTAFWQKYPNPYSTNVLTEDVIFREVTPDNRLLSRRLLTKT--GPVPRWAESFFTSFTAYYVIEDSVVDPVNKTMVTFTRNISHT 101

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Cavefish
Match: prelid3b (PRELI domain containing 3B [Source:NCBI gene;Acc:103030743])

HSP 1 Score: 54.6842 bits (130), Expect = 1.515e-8
Identity = 47/186 (25.27%), Postives = 85/186 (45.70%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKE---FILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSV-KSSIGYEHVIKNNLLLNVPINSKFIPAR 668
            K + +    N+ W  V     ++YPNP    V   D++ R +   G L++KRL + +    LP  +K +  N     ++ E+S++ P+++  +  + N+  + N   + E+ +Y P    P++T + +   I  K  +  S   ++ LM    ST+  K     E VI+    LN  I    I AR
Sbjct:    2 KIWTSEHIFNHPWETVTKAAMQKYPNPMNPSVFGVDVLDRSVDHQGRLHSKRLLSTEW--GLPSIVKAIIGNTRTCTYVQEQSMVDPKEKTFELQSSNITFT-NMVSVDERLTYRPHPQDPEKTVLTQEAIISVKGVSLSS--YLEGLMASTISTNAGKGREAMEWVIRR---LNAEIEELAITAR 179

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Cavefish
Match: prelid3b (PRELI domain containing 3B [Source:NCBI gene;Acc:103030743])

HSP 1 Score: 51.9878 bits (123), Expect = 1.354e-7
Identity = 45/176 (25.57%), Postives = 81/176 (46.02%), Query Frame = 3

Query:  153 YTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKE---FILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSV-KSSIGYEHVIKNNLLLNVPINSKFIPAR 668
            + W  V     ++YPNP    V   D++ R +   G L++KRL + +    LP  +K +  N     ++ E+S++ P+++  +  + N+  + N   + E+ +Y P    P++T + +   I  K  +  S   ++ LM    ST+  K     E VI+    LN  I    I AR
Sbjct:   16 HPWETVTKAAMQKYPNPMNPSVFGVDVLDRSVDHQGRLHSKRLLSTEW--GLPSIVKAIIGNTRTCTYVQEQSMVDPKEKTFELQSSNITFT-NMVSVDERLTYRPHPQDPEKTVLTQEAIISVKGVSLSS--YLEGLMASTISTNAGKGREAMEWVIRR---LNAEIEELAITAR 183

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Yeast
Match: UPS1 (Phosphatidic acid transfer protein; plays a role in phospholipid metabolism by transporting phosphatidic acid from the outer to the inner mitochondrial membrane; localizes to the mitochondrial intermembrane space; null mutant has altered cardiolipin and phosphatidic acid levels; ortholog of human PRELI [Source:SGD;Acc:S000004183])

HSP 1 Score: 55.8398 bits (133), Expect = 5.871e-10
Identity = 46/153 (30.07%), Postives = 70/153 (45.75%), Query Frame = 3

Query:  168 VASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKN--KEFILEESIISPRKQLMDTLTYNVGESKNYGIL-YEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIK 617
            V+  F+ RYPNPY+ HVLS D I R +  +G+L T RL  K     LP  +K   +   + +I+E S+++P    M T T N+  +   GI+  E+ +     S    T  +  +   S  N      V      K+     KS +G   VI+
Sbjct:   18 VSRAFFNRYPNPYSPHVLSIDTISRNVDQEGNLRTTRLLKKS--GKLPTWVKPFLRGITETWIIEVSVVNPANSTMKTYTRNLDHT---GIMKVEEYTTYQFDSATSSTIADSRVKFSSGFNMGIKSKVEDWSRTKFDENVKKSRMGMAFVIQ 165

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Yeast
Match: UPS2 (Mitochondrial intermembrane space protein; involved in phospholipid metabolism; forms complex with Mdm35p that transfers phosphatidylserine from outer membrane to inner membrane for phosphatidylethanolamine synthesis; null mutant has defects in mitochondrial morphology; similar to Ups1p, Ups3p and to human PRELI; UPS2 has a paralog, UPS3, that arose from the whole genome duplication [Source:SGD;Acc:S000004158])

HSP 1 Score: 54.6842 bits (130), Expect = 2.366e-9
Identity = 48/176 (27.27%), Postives = 85/176 (48.30%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGS-LYTKRLTTKKHFKALPFTIKYLFK--NKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSV--------KSSIGYEHVIK 617
            K ++ S   NY W+ V +  WK+YPN  + HV++ D++ RE+   G  L T+RL T K  + +P  I  +    N   + E S++   K+ +   + N+    N   +YE  +Y+P    P  +    L   E+++ A+ S   I+ L  K +  SV        K  +G++ V++
Sbjct:    2 KLFQNSYDFNYPWDQVTAANWKKYPNEISTHVIAVDVLRRELKDQGKVLVTERLITVK--QGVPKWIMMMLGGTNMSHVREVSVVDLNKKSLTMRSCNLTMC-NLLKVYETVTYSPH---PDDSANKTLFQQEAQITAYGS---IRKLCNKMEDWSVQRFCENAKKGKMGFDAVLQ 168

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Yeast
Match: UPS3 (Mitochondrial protein of unknown function; similar to Ups1p and Ups2p which are involved in regulation of mitochondrial cardiolipin and phosphatidylethanolamine levels; null is viable but interacts synthetically with ups1 and ups2 mutations; UPS3 has a paralog, UPS2, that arose from the whole genome duplication [Source:SGD;Acc:S000002593])

HSP 1 Score: 47.7506 bits (112), Expect = 3.098e-7
Identity = 40/169 (23.67%), Postives = 73/169 (43.20%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGS-LYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGIL--YEKCSYTPTSSVPQQT--FINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            K+++ S   +Y W  V +  W +YPN  + HV++ D++ RE+   G  L T+RL T +       +I     N  ++ E S +  R + +   + N+       IL  YE   Y P    P     F     ++       FS  V    + ++   +VK  +G++ ++
Sbjct:    2 KSFQKSYEFDYPWEKVTTANWMKYPNKISTHVIAVDVLRRELKEHGDVLLTERLITIRQNTPHWMSILVGNTNLAYVREVSTVDRRDRSLTMRSCNMTFPH---ILKCYETVRYVPHPKNPSNVTLFKQDAKFLSGVPTKTFSEKVENWGVKRFSDNAVKGKVGFDSIL 167

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO37602 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFC7])

HSP 1 Score: 87.4261 bits (215), Expect = 5.307e-21
Identity = 52/158 (32.91%), Postives = 92/158 (58.23%), Query Frame = 3

Query:  147 LNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALP-FTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIK 617
            L Y W+ V++ +W+RYPNP++KHVLSED++ R ++ +  L TKRL TK +   LP +  +++      I+EES++ P  + + T T N+   K   ++ EKC YT +    + T   +  W+ S +   F+R +    + +YK+   K+S G E++++
Sbjct:    2 LRYAWDQVSAAYWRRYPNPWSKHVLSEDVVSR-VVEEDKLKTKRLLTKTN--RLPRWGERFVNSRVACIIEESVVDPVAKTLTTYTRNIT-FKTLMVVEEKCVYTVSPQNKEWTTCERQSWVTSGVYG-FARAIEAFGIERYKNNVKKTSKGLEYILE 154

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Medaka
Match: prelid1a (PRELI domain-containing protein 1, mitochondrial [Source:NCBI gene;Acc:101174272])

HSP 1 Score: 104.76 bits (260), Expect = 1.523e-26
Identity = 61/170 (35.88%), Postives = 100/170 (58.82%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFK---NKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAF-FSRPVIKCLMYKYKSTSVKSSIGYEHVI 614
            M K +  S  L  TW+ V + FW+RYPNPY+ HVL+EDII RE+ P+  L ++RL TK   ++  +  +YL K   +  +I+E+SI+ P+K+ M TLT+N+  ++   +  E+C Y         T I +  WI S  N F  SR + +  + ++K++  K+  G+E+V+
Sbjct:    1 MVKYFYCSGLLKSTWDQVCTAFWQRYPNPYSNHVLTEDIIFREVTPNNCLISRRLLTKTS-RSPRWMERYLPKHMASSAYIIEDSIVDPQKRTMTTLTWNISHARLMSV-EERCHYEVDPENGSWTEIKREAWISS--NVFGLSRAIQEFGLARFKTSVTKTMKGFEYVL 166

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Medaka
Match: ENSORLT00000008104.2 (PRELI domain-containing protein 1, mitochondrial [Source:NCBI gene;Acc:101164954])

HSP 1 Score: 95.9005 bits (237), Expect = 3.115e-23
Identity = 54/172 (31.40%), Postives = 97/172 (56.40%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKN 620
            M K + ++  +  TW+ V S FW+RYPNP++ HVL+ED+++RE+  D  L ++RL  K +   LP   + LF        +I+E+SI+ P ++ + T T+N+  +    +  E+C +  +   P  T + +  WI S +   FS+P+ +  + ++KS  VK+  G E+ + N
Sbjct:    1 MVKYFCSNIDIKSTWDHVVSAFWQRYPNPFSTHVLTEDVVYRELTADHRLLSRRLLMKTN--RLPRWAERLFPAGMSRSVYIVEDSIVDPVERSLTTYTWNLNHTTLMSV-EERCVFLESVEHPATTQLKREAWISSSIYG-FSKPIQEFGLARFKSNQVKALKGLEYALTN 168

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Medaka
Match: ENSORLT00000035710.1 (PRELI domain-containing protein 1, mitochondrial [Source:NCBI gene;Acc:101164954])

HSP 1 Score: 95.9005 bits (237), Expect = 4.125e-23
Identity = 54/172 (31.40%), Postives = 97/172 (56.40%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKN 620
            M K + ++  +  TW+ V S FW+RYPNP++ HVL+ED+++RE+  D  L ++RL  K +   LP   + LF        +I+E+SI+ P ++ + T T+N+  +    +  E+C +  +   P  T + +  WI S +   FS+P+ +  + ++KS  VK+  G E+ + N
Sbjct:    1 MVKYFCSNIDIKSTWDHVVSAFWQRYPNPFSTHVLTEDVVYRELTADHRLLSRRLLMKTN--RLPRWAERLFPAGMSRSVYIVEDSIVDPVERSLTTYTWNLNHTTLMSV-EERCVFLESVEHPATTQLKREAWISSSIYG-FSKPIQEFGLARFKSNQVKALKGLEYALTN 168

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Medaka
Match: prelid1b (PRELI domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-050522-169])

HSP 1 Score: 74.7146 bits (182), Expect = 2.112e-16
Identity = 36/106 (33.96%), Postives = 63/106 (59.43%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLF----KNKEFILEESIISPRKQLMDTLTYNVGESK 422
            M + + +  ++   W+ V + FW+RYPNPY+ HVL+ED+++RE+ P+  L ++RL TK     LP   + +F        ++LE+SI+ P+     T T+N+  +K
Sbjct:    1 MGRYFHSEVHILSPWDQVVAAFWQRYPNPYSTHVLTEDVLYRELTPNNHLLSRRLLTKT--NRLPGWAERVFPAHVARAVYVLEDSIVDPQTHTFTTKTWNLNHNK 104

[Close]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Medaka
Match: PRELID3B (PRELI domain containing protein 3B [Source:NCBI gene;Acc:101164398])

HSP 1 Score: 56.6102 bits (135), Expect = 2.691e-9
Identity = 33/133 (24.81%), Postives = 66/133 (49.62%), Query Frame = 3

Query:  123 KAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKR-LTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESK 518
            K + +    N+ W  V     ++YPNP    V   D++ R++ PDG L++ R L+T+    A+  +I  + +   ++ E S++ P ++  +  + N+  + N   + EK +Y P    P++T + +   I  K
Sbjct:    2 KIWASEHIFNHPWETVTKAAMQKYPNPMNPGVFGVDVLDRKVDPDGRLHSTRLLSTEWGLPAIAKSIIGVTRTCTYVQEHSVVDPNQRTFELQSTNISFT-NLVSVDEKLTYKPHPQDPEKTVLTQEALISVK 133

[Close]

BLAST of PRELI domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000023721.1 (SMESG000023721.1)

HSP 1 Score: 407.912 bits (1047), Expect = 1.594e-145
Identity = 198/199 (99.50%), Postives = 198/199 (99.50%), Query Frame = 3

Query:   87 MSPMKETDDCMTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVPINSKFIPARKPEVS 683
            MSPMKETDDCMTK YKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVPINSKFIPARKPEVS
Sbjct:    1 MSPMKETDDCMTKGYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVPINSKFIPARKPEVS 199

[Close]

BLAST of PRELI domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000023721.1 (SMESG000023721.1)

HSP 1 Score: 401.749 bits (1031), Expect = 4.506e-143
Identity = 195/196 (99.49%), Postives = 195/196 (99.49%), Query Frame = 3

Query:   96 MKETDDCMTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVPINSKFIPARKPEVS 683
            MKETDDCMTK YKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVPINSKFIPARKPEVS
Sbjct:    1 MKETDDCMTKGYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVPINSKFIPARKPEVS 196

[Close]

BLAST of PRELI domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000023721.1 (SMESG000023721.1)

HSP 1 Score: 384.8 bits (987), Expect = 1.793e-136
Identity = 188/189 (99.47%), Postives = 188/189 (99.47%), Query Frame = 3

Query:  117 MTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVPINSKFIPARKPEVS 683
            MTK YKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVPINSKFIPARKPEVS
Sbjct:    1 MTKGYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVPINSKFIPARKPEVS 189

[Close]

BLAST of PRELI domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000023723.1 (SMESG000023723.1)

HSP 1 Score: 159.073 bits (401), Expect = 7.819e-48
Identity = 84/180 (46.67%), Postives = 121/180 (67.22%), Query Frame = 3

Query:   87 MSPMKETDDCMTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDIIHREILPDGSLYTKRLTTKKHFKALPFTIKYLFKN-KEFILEESIISPRKQLMDTLTYNVGESKNYGILYEKCSYTPTSSVPQ-QTFINKLMWIESKMNAFFSRPVIKCLMYKYKSTSVKSSIGYEHVIKN 620
            M+   E+D  +  +YKT  YLNY+W IVA +FWKRYPNP+AKHVLSEDII R+ L +G++Y++RL  K+  K++P  I Y     KE+ILEESII+P  + + TL++N GE++ Y I YE C Y     + Q +T INK  W+ES   + F   +I  L+Y+YKST++ S+ G  +VI++
Sbjct:    1 MTYSNESD--LINSYKTVAYLNYSWKIVALYFWKRYPNPFAKHVLSEDIISRKFLMNGNMYSQRLIVKQ-MKSVPRWISYFTDQFKEYILEESIIAPDNERIFTLSWNFGENRKYAICYESCEYQSDVFMNQARTKINKQAWVESSWESEFRSTLISFLIYRYKSTNIASTAGLNYVIES 177

The following BLAST results are available for this feature:

BLAST of PRELI domain-containing protein 1 vs. Ensembl Human
BLAST of PRELI domain-containing protein 1 vs. Ensembl Celegans
BLAST of PRELI domain-containing protein 1 vs. Ensembl Fly
BLAST of PRELI domain-containing protein 1 vs. Ensembl Zebrafish
BLAST of PRELI domain-containing protein 1 vs. Ensembl Xenopus
BLAST of PRELI domain-containing protein 1 vs. Ensembl Mouse
BLAST of PRELI domain-containing protein 1 vs. UniProt/SwissProt
BLAST of PRELI domain-containing protein 1 vs. TrEMBL
BLAST of PRELI domain-containing protein 1 vs. Ensembl Cavefish
BLAST of PRELI domain-containing protein 1 vs. Ensembl Sea Lamprey
BLAST of PRELI domain-containing protein 1 vs. Ensembl Yeast
BLAST of PRELI domain-containing protein 1 vs. Ensembl Nematostella
BLAST of PRELI domain-containing protein 1 vs. Ensembl Medaka
BLAST of PRELI domain-containing protein 1 vs. Planmine SMEST

BLAST of PRELI domain-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PRELID1	5.728e-29	34.71	PRELI domain containing 1 [Source:HGNC Symbol;Acc:...	[more]
PRELID1	1.041e-28	34.71	PRELI domain containing 1 [Source:HGNC Symbol;Acc:...	[more]
PRELID1	1.566e-22	40.57	PRELI domain containing 1 [Source:HGNC Symbol;Acc:...	[more]
PRELID3B	2.468e-8	25.00	PRELI domain containing 3B [Source:HGNC Symbol;Acc...	[more]
PRELID3A	1.650e-7	25.20	PRELI domain containing 3A [Source:HGNC Symbol;Acc...	[more]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
B0334.4	2.108e-11	31.09	pep chromosome:WBcel235:II:11495692:11496663:1 gen...	[more]
F15D3.6	9.635e-7	23.90	pep chromosome:WBcel235:I:11572121:11577488:-1 gen...	[more]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
prel	2.752e-15	29.94	gene:FBgn0033413 transcript:FBtr0333003	[more]
prel	2.752e-15	29.94	gene:FBgn0033413 transcript:FBtr0300293	[more]
slmo	3.530e-7	26.92	gene:FBgn0029161 transcript:FBtr0299810	[more]
slmo	3.530e-7	26.92	gene:FBgn0029161 transcript:FBtr0343130	[more]
slmo	3.530e-7	26.92	gene:FBgn0029161 transcript:FBtr0112945	[more]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
prelid1a	4.831e-28	34.91	PRELI domain containing 1a [Source:ZFIN;Acc:ZDB-GE...	[more]
prelid1a	4.831e-28	34.91	PRELI domain containing 1a [Source:ZFIN;Acc:ZDB-GE...	[more]
prelid1b	2.078e-25	31.18	PRELI domain containing 1b [Source:ZFIN;Acc:ZDB-GE...	[more]
prelid3b	3.942e-8	25.27	PRELI domain containing 3 [Source:ZFIN;Acc:ZDB-GEN...	[more]
prelid3a	1.276e-6	24.22	PRELI domain containing 3A [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
jak3	2.893e-25	33.52	Janus kinase 3 (a protein tyrosine kinase, leukocy...	[more]
lcat	3.650e-7	22.66	lecithin-cholesterol acyltransferase [Source:Xenba...	[more]
lcat	4.918e-7	24.39	lecithin-cholesterol acyltransferase [Source:Xenba...	[more]
lcat	1.236e-6	24.58	lecithin-cholesterol acyltransferase [Source:Xenba...	[more]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Prelid1	4.159e-29	35.29	PRELI domain containing 1 [Source:MGI Symbol;Acc:M...	[more]
Prelid3b	2.180e-8	24.22	PRELI domain containing 3B [Source:MGI Symbol;Acc:...	[more]
Prelid3a	3.024e-6	23.81	PRELI domain containing 3A [Source:MGI Symbol;Acc:...	[more]

BLAST of PRELI domain-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8R107\|PRLD1_MOUSE	2.909e-28	35.29	PRELI domain-containing protein 1, mitochondrial O...	[more]
sp\|Q9Y255\|PRLD1_HUMAN	4.998e-28	34.71	PRELI domain-containing protein 1, mitochondrial O...	[more]
sp\|Q32KN9\|PRLD1_BOVIN	6.081e-27	34.71	PRELI domain-containing protein 1, mitochondrial O...	[more]
sp\|Q90673\|PRLD1_CHICK	9.189e-24	33.75	PRELI domain-containing protein 1, mitochondrial O...	[more]
sp\|Q9UT07\|UPS1_SCHPO	3.188e-17	31.95	Protein ups1 homolog OS=Schizosaccharomyces pombe ...	[more]

BLAST of PRELI domain-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4S2LFP5	1.381e-37	41.14	PRELI/MSF1 domain-containing protein OS=Opisthorch...	[more]
A0A1S8WL23	1.009e-34	39.87	PRELI-like family protein OS=Opisthorchis viverrin...	[more]
A0A4E0S280	2.452e-33	39.74	PRELI domain-containing protein 1 mitochondrial OS...	[more]
A0A504YUG6	2.478e-33	39.74	PRELI domain-containing protein 1 mitochondrial OS...	[more]
A0A5J4NS29	2.275e-31	41.03	PRELI/MSF1 domain-containing protein OS=Paragonimu...	[more]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
prelid1a	2.157e-27	34.91	PRELI domain containing 1 [Source:NCBI gene;Acc:10...	[more]
prelid1b	1.342e-25	32.94	PRELI domain-containing protein 1, mitochondrial-l...	[more]
ENSAMXT00000038061.1	4.629e-15	37.78	pep primary_assembly:Astyanax_mexicanus-2.0:4:2462...	[more]
prelid3b	1.515e-8	25.27	PRELI domain containing 3B [Source:NCBI gene;Acc:1...	[more]
prelid3b	1.354e-7	25.57	PRELI domain containing 3B [Source:NCBI gene;Acc:1...	[more]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PRELI domain-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
UPS1	5.871e-10	30.07	Phosphatidic acid transfer protein; plays a role i...	[more]
UPS2	2.366e-9	27.27	Mitochondrial intermembrane space protein; involve...	[more]
UPS3	3.098e-7	23.67	Mitochondrial protein of unknown function; similar...	[more]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO37602	5.307e-21	32.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of PRELI domain-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
prelid1a	1.523e-26	35.88	PRELI domain-containing protein 1, mitochondrial [...	[more]
ENSORLT00000008104.2	3.115e-23	31.40	PRELI domain-containing protein 1, mitochondrial [...	[more]
ENSORLT00000035710.1	4.125e-23	31.40	PRELI domain-containing protein 1, mitochondrial [...	[more]
prelid1b	2.112e-16	33.96	PRELI domain containing 1b [Source:ZFIN;Acc:ZDB-GE...	[more]
PRELID3B	2.691e-9	24.81	PRELI domain containing protein 3B [Source:NCBI ge...	[more]

BLAST of PRELI domain-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4


Match Name	E-value	Identity	Description
SMESG000023721.1	1.594e-145	99.50	SMESG000023721.1	[more]
SMESG000023721.1	4.506e-143	99.49	SMESG000023721.1	[more]
SMESG000023721.1	1.793e-136	99.47	SMESG000023721.1	[more]
SMESG000023723.1	7.819e-48	46.67	SMESG000023723.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30024181 ID=SMED30024181|Name=PRELI domain-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=940bp
GAAAATAATTAATTTAAAGCATTATAACAGTATAATTTTAAAGTTTAAAA
TATTAGTTTATAGATTCGAAATATTTTGTTTCTAATATGTCGCCTATGAA
GGAAACAGATGATTGTATGACCAAAGCTTATAAAACTTCAACGTATCTAA
ATTACACTTGGAATATTGTTGCCTCATTTTTTTGGAAGAGATATCCAAAT
CCCTATGCAAAACATGTGCTGTCTGAAGATATCATACATAGAGAAATATT
GCCAGATGGTAGTCTCTATACAAAGCGGCTTACAACTAAAAAACATTTTA
AAGCATTACCATTTACCATTAAATACTTATTTAAAAATAAAGAATTTATT
TTAGAAGAAAGTATAATATCTCCTCGTAAACAATTAATGGATACATTGAC
TTATAATGTTGGAGAATCGAAAAATTATGGCATACTTTATGAGAAATGCT
CCTATACTCCAACGAGTTCTGTTCCACAGCAAACATTTATTAATAAACTA
ATGTGGATTGAGTCGAAAATGAATGCATTCTTTTCACGTCCAGTTATTAA
ATGTTTGATGTATAAATATAAGTCGACCAGTGTGAAAAGTAGTATTGGAT
ATGAACACGTAATCAAGAATAACCTACTGTTAAATGTTCCAATCAATTCC
AAATTTATTCCAGCTCGTAAACCAGAAGTCAGTTGAGGCTGATTCGAATT
TCTTTTCCCTAACAATTACAACTCCAATTATTATATTAGAACTGTTTTCT
TTAATAAATAGATGTTGCTGTAATCTACTGGTTATTCAATTTATTTATCC
CTACTACTTTGATTTGGCAATTTTATTCTATTTTTTTTTATTGGTAAGTC
AAATGCATTTTTATATTTATAGTTTCATAGATATTTTTATATCTAATGTT
GCTGGCAATATCAATATTCATAACAATATATTTTTAGCAG

protein sequence of SMED30024181-orf-1

>SMED30024181-orf-1 ID=SMED30024181-orf-1|Name=SMED30024181-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=200bp
MSPMKETDDCMTKAYKTSTYLNYTWNIVASFFWKRYPNPYAKHVLSEDII
HREILPDGSLYTKRLTTKKHFKALPFTIKYLFKNKEFILEESIISPRKQL
MDTLTYNVGESKNYGILYEKCSYTPTSSVPQQTFINKLMWIESKMNAFFS
RPVIKCLMYKYKSTSVKSSIGYEHVIKNNLLLNVPINSKFIPARKPEVS*

protein sequence of SMED30024181-orf-2

>SMED30024181-orf-2 ID=SMED30024181-orf-2|Name=SMED30024181-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=102bp
MFQSIPNLFQLVNQKSVEADSNFFSLTITTPIIILELFSLINRCCCNLLV
IQFIYPYYFDLAILFYFFLLVSQMHFYIYSFIDIFISNVAGNINIHNNIF
LA

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000070	intestinal phagocyte
PLANA:0000101	muscle cell
PLANA:0000142	posterior region of the whole animal
PLANA:0002056	medial muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR037365	Slowmo/Ups
IPR006797	PRELI/MSF1_dom

Vocabulary: **cellular component**
Term	Definition
GO:0005654	nucleoplasm
GO:0005739	mitochondrion
GO:0005758	mitochondrial intermembrane space
GO:0043234	protein complex

Vocabulary: **biological process**
Term	Definition
GO:0006810	transport
GO:0006869	lipid transport
GO:0006915	apoptotic process
GO:0010917	negative regulation of mitochondrial membrane potential
GO:0010950	positive regulation of endopeptidase activity
GO:0015914	phospholipid transport
GO:0043066	negative regulation of apoptotic process
GO:0045580	regulation of T cell differentiation
GO:0051881	regulation of mitochondrial membrane potential
GO:0070234	positive regulation of T cell apoptotic process
GO:0090201	negative regulation of release of cytochrome c from mitochondria
GO:0097035	regulation of membrane lipid distribution
GO:1901857	positive regulation of cellular respiration
GO:2001140	positive regulation of phospholipid transport

Vocabulary: **molecular function**
Term	Definition
GO:1990050	phosphatidic acid transporter activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006797	PRELI/MSF1 domain	PFAM	PF04707	PRELI	coord: 28..178 e-value: 1.5E-28 score: 99.6
IPR006797	PRELI/MSF1 domain	PROSITE	PS50904	PRELI_MSF1	coord: 12..184 score: 25.346
None	No IPR available	PANTHER	PTHR11158:SF29	PRELI DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL	coord: 11..177
IPR037365	Slowmo/Ups family	PANTHER	PTHR11158	MSF1/PX19 RELATED	coord: 11..177

Main menu

PRELI domain-containing protein 1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

blazegraph-runner