Epithelial discoidin domain-containing receptor

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILF-DDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITVS--NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD 1223
            AWCP+ PV  +   E+LQI+  +  FIT + TQGR  G +G EF P Y  +Y R+ ++ W  + +    +++  N++  +   +  E  +VA  +R +P++  + NVC+R+ LYGC + DG+  Y  P G        SI++ +D  YDG    + T    G+G+L D V     FT+ +  +    +  V W+ ++    +I ++F+F ++R F ++K++            K +   F  E +E   + I+  + +   NP+       ++ L    +  I  + +F   W+  +E+ F++D
Sbjct:   71 AWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTR-WISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMT---EGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSAR---FVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSD 367          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNS-MLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + YLS L  VH+D++ RNC +G+++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+FGVT+WE FT CQ +PYS L ++          +I N+     +    + LP                 P      +  +M  CW+ D   RPSFQ++H LL
Sbjct:  695 ASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDE---------QVIENTGEFFRDQGRQTYLP----------------QPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILF-DDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITVS--NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD 1223
            AWCP+ PV  +   E+LQI+  +  FIT + TQGR  G +G EF P Y  +Y R+ ++ W  + +    +++  N++  +   +  E  +VA  +R +P++  + NVC+R+ LYGC + DG+  Y  P G        SI++ +D  YDG    + T    G+G+L D V     FT+ +  +    +  V W+ ++    +I ++F+F ++R F ++K++            K +   F  E +E   + I+  + +   NP+       ++ L    +  I  + +F   W+  +E+ F++D
Sbjct:   71 AWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTR-WISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMT---EGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSAR---FVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSD 367          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNS-MLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + YLS L  VH+D++ RNC +G+++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+FGVT+WE FT CQ +PYS L ++          +I N+     +    + LP                 P      +  +M  CW+ D   RPSFQ++H LL
Sbjct:  695 ASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDE---------QVIENTGEFFRDQGRQTYLP----------------QPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILF-DDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITVS--NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD 1223
            AWCP+ PV  +   E+LQI+  +  FIT + TQGR  G +G EF P Y  +Y R+ ++ W  + +    +++  N++  +   +  E  +VA  +R +P++  + NVC+R+ LYGC + DG+  Y  P G        SI++ +D  YDG    + T    G+G+L D V     FT+ +  +    +  V W+ ++    +I ++F+F ++R F ++K++            K +   F  E +E   + I+  + +   NP+       ++ L    +  I  + +F   W+  +E+ F++D
Sbjct:   71 AWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTR-WISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMT---EGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSAR---FVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSD 367          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNS-MLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + YLS L  VH+D++ RNC +G+++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+FGVT+WE FT CQ +PYS L ++          +I N+     +    + LP                 P      +  +M  CW+ D   RPSFQ++H LL
Sbjct:  695 ASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDE---------QVIENTGEFFRDQGRQTYLP----------------QPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849          

Query: 2151 ILVARFKPNNFKIDSKSLFYRQCFAKLREDFS--SHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXX------XXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCN 3035
            + V   +P+  K  S SLF R  F K  +  S    PN+I ++G C+       +   ++  +    ++  FL    L  K  + +      +Q   +       V  Q+A  + YL+ L  VH+D++ RNC +GE+F + ++DF +    +  DY  ++                LP+ WM WE I+MG ++T SD+W+FGVT+WE+   C+ +P+  L ++          +I N+     +         R + L++        P    + + ++M  CW  +   RP F +LH  L  
Sbjct:  111 VAVKILRPDATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCV-----QDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDE---------QVIENAGEFFRD-------QGRQVYLSR--------PPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAE 372          

Query: 2151 ILVARFKPNNFKIDSKSLFYRQCFAKLREDFS--SHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXX------XXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCN 3035
            + V   +P+  K  S SLF R  F K  +  S    PN+I ++G C+       +   ++  +    ++  FL    L  K  + +      +Q   +       V  Q+A  + YL+ L  VH+D++ RNC +GE+F + ++DF +    +  DY  ++                LP+ WM WE I+MG ++T SD+W+FGVT+WE+   C+ +P+  L ++          +I N+     +         R + L++        P    + + ++M  CW  +   RP F +LH  L  
Sbjct:  111 VAVKILRPDATKNASFSLFSRNDFLKEVKIMSRLKDPNIIRLLGVCV-----QDDPLCMITDYMENGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDE---------QVIENAGEFFRD-------QGRQVYLSR--------PPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAE 372          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDL---FSLDLKRFRSKLIIIKLYF--KSDWIAINEVMFETD----DLPKDSSSIPDLYSTVNV 1277
            AWCP   +++   EWLQI FS    IT + TQGR D   G E+  ++   Y R S   W  Y D    E IPAN D  +A  +  +  ++A RIRIVP+S+    VC+R+ ++GC F D +  Y + +GD      + I + D +YDG   +N   L GG+G+L D  +      +N  +   V W+RK +   ++ L F+F ++R    + I+ +           S TV F   N K  S     +  +NP   + ++     + +    +K+  I+L F   SDW+ I+EV FE++    +L  D   IPD  S  +V
Sbjct:   37 AWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDDSLVFYNVDQGDL----QSGISYHDFSYDGN-LANSPHLTGGIGKLYDGEVGKNNVFVNHHK--WVGWRRKRN--GNVKLAFEFSELRNISGILIHTSNEFKKSAKAFSSATVLF-SINGKDFSDTI--VHFNNPEDTESEVPRWIRIPVNNRIAKVAKIRLNFGTDSDWLFISEVNFESNHTNIELLNDDVVIPDSVSYFSV 345          

Query: 2031 EKALSRIPEIDANQINLEALVTEGEIGAFVSGRLGKSNIEILVARFKPNNFKIDSKSLFYRQ--CFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTS 3050
            E   + +PEI  +++   + + +GE G     +L        VA  K +      +  F+R+      L+     HPN++ ++G C +           +  +    ++ +++ K   I  +  IS                QLA  L+YL     VH+D++ARNC +    ++ ++DF +    +  +Y  +       EG        LP+ WM WEA+++G +ST SD+W FGVTMWEIF+ C  KPYS + +          +++ N   +++           T  L Q++      P   SK   + +  CW  + + RPSF+ +H  L +L+ TS
Sbjct:  483 EVYCTTLPEIARDKLICVSRIGQGEFGEVDLCQLENRK----VAVKKLHGISQADEFSFHREIRVLGSLK-----HPNVVEVVGVCTI-----QKPILCIMEYMENGDLKSYILKNPTIQTSQCISIC-------------TQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYYKV-------EGK-----FVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDD---------DVVENLQSMSS-----------TGSLKQVLSRPRMCP---SKLYNEQILPCWNYESSRRPSFENVHLHLQSLVHTS 762          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDL---FSLDLKRFRSKLIIIKLYF--KSDWIAINEVMFETD----DLPKDSSSIPDLYSTVNV 1277
            AWCP   +++   EWLQI FS    IT + TQGR D   G E+  ++   Y R S   W  Y D    E IPAN D  +A  +  +  ++A RIRIVP+S+    VC+R+ ++GC F D +  Y + +GD      + I + D +YDG   +N   L GG+G+L D  +      +N  +   V W+RK +   ++ L F+F ++R    + I+ +           S TV F   N K  S     +  +NP   + ++     + +    +K+  I+L F   SDW+ I+EV FE++    +L  D   IPD  S  +V
Sbjct:   37 AWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDDSLVFYNVDQGDL----QSGISYHDFSYDGN-LANSPHLTGGIGKLYDGEVGKNNVFVNHHK--WVGWRRKRN--GNVKLAFEFSELRNISGILIHTSNEFKKSAKAFSSATVLF-SINGKDFSDTI--VHFNNPEDTESEVPRWIRIPVNNRIAKVAKIRLNFGTDSDWLFISEVNFESNHTNIELLNDDVVIPDSVSYFSV 345          

Query: 2031 EKALSRIPEIDANQINLEALVTEGEIGAFVSGRLGKSNIEILVARFKPNNFKIDSKSLFYRQ--CFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTS 3050
            E   + +PEI  +++   + + +GE G     +L        VA  K +      +  F+R+      L+     HPN++ ++G C +           +  +    ++ +++ K   I  +  IS                QLA  L+YL     VH+D++ARNC +    ++ ++DF +    +  +Y  +       EG        LP+ WM WEA+++G +ST SD+W FGVTMWEIF+ C  KPYS + +          +++ N   +++           T  L Q++      P   SK   + +  CW  + + RPSF+ +H  L +L+ TS
Sbjct:  483 EVYCTTLPEIARDKLICVSRIGQGEFGEVDLCQLENRK----VAVKKLHGISQADEFSFHREIRVLGSLK-----HPNVVEVVGVCTI-----QKPILCIMEYMENGDLKSYILKNPTIQTSQCISIC-------------TQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYYKV-------EGK-----FVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDD---------DVVENLQSMSS-----------TGSLKQVLSRPRMCP---SKLYNEQILPCWNYESSRRPSFENVHLHLQSLVHTS 762          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDL---FSLDLKRFRSKLIIIKLYF--KSDWIAINEVMFETD----DLPKDSSSIPDLYSTVNV 1277
            AWCP   +++   EWLQI FS    IT + TQGR D   G E+  ++   Y R S   W  Y D    E IPAN D  +A  +  +  ++A RIRIVP+S+    VC+R+ ++GC F D +  Y + +GD      + I + D +YDG   +N   L GG+G+L D  +      +N  +   V W+RK +   ++ L F+F ++R    + I+ +           S TV F   N K  S     +  +NP   + ++     + +    +K+  I+L F   SDW+ I+EV FE++    +L  D   IPD  S  +V
Sbjct:   67 AWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDDSLVFYNVDQGDL----QSGISYHDFSYDGN-LANSPHLTGGIGKLYDGEVGKNNVFVNHHK--WVGWRRKRN--GNVKLAFEFSELRNISGILIHTSNEFKKSAKAFSSATVLF-SINGKDFSDTI--VHFNNPEDTESEVPRWIRIPVNNRIAKVAKIRLNFGTDSDWLFISEVNFESNHTNIELLNDDVVIPDSVSYFSV 375          

Query: 2031 EKALSRIPEIDANQINLEALVTEGEIGAFVSGRLGKSNIEILVARFKPNNFKIDSKSLFYRQ--CFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTS 3050
            E   + +PEI  +++   + + +GE G     +L        VA  K +      +  F+R+      L+     HPN++ ++G C +           +  +    ++ +++ K   I  +  IS                QLA  L+YL     VH+D++ARNC +    ++ ++DF +    +  +Y  +       EG        LP+ WM WEA+++G +ST SD+W FGVTMWEIF+ C  KPYS + +          +++ N   +++           T  L Q++      P   SK   + +  CW  + + RPSF+ +H  L +L+ TS
Sbjct:  513 EVYCTTLPEIARDKLICVSRIGQGEFGEVDLCQLENRK----VAVKKLHGISQADEFSFHREIRVLGSLK-----HPNVVEVVGVCTI-----QKPILCIMEYMENGDLKSYILKNPTIQTSQCISIC-------------TQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYYKV-------EGK-----FVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDD---------DVVENLQSMSS-----------TGSLKQVLSRPRMCP---SKLYNEQILPCWNYESSRRPSFENVHLHLQSLVHTS 792          

Query:  141 ITIIFLSSQLSANTETSPRKDADGYCATGILQ-DSHSIRISASSVLRNDPDFGPESSRIVGLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPI--NKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            I ++ L+   +  T T  R D  G  A G+   D    +I+ASS   +    GP+++R   L   L   AWCP   +++   E+LQ+  + T  IT + TQGR  +G   EF   Y  DY R  SQ W RY +      +  N D      +  +  +VA+RIR VP S     VC+R  ++GC  +   +   +P G  +     ++ F D  ++  +   E+ ++ G+G L D  +  +A+P   N+M +  + W R T     I +LF+F +V  F  + +      +   D   S       K     SQI++S   S    +    F + L     + + I + F SDW+ + EV F
Sbjct:    3 IALVLLAIYGTTTTNTL-RIDQCGENALGMQNGDIADSQITASSSF-DKQSVGPQNAR---LHSELASGAWCPKPQINSKSYEFLQVTLNDTFLITSVETQGRYGNGTGREFASHYMIDYLRPGSQ-WIRYKNRTGHVYMDGNFDTTTPVIRVLDPPIVASRIRFVPSSKNTRTVCMRAEIHGCKHEGVTYYSTVPDGSRL----DTLDFKDSMFEDSQIYTESGIKRGLGLLTDGFV-AQASPFEKNQMNNSWIGWNRDTT-DGRITILFEFEEVHNFTDVVLATFGNRIDGIDVIFSQD----GKTFPLFSQISSSERQSLNNTSRRYDFRVPLHNRAGRKVRISIKFSSDWMFLTEVHF 348          

Query: 2463 ALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKL 3017
            A++YL  + IVH   +  N  +   FH  +                      +  G  H    H  L +   E+I+   ++ KSD W+   T++E+  +C+ +PY  L N+          I+ N+  + ++ P++++               P  P   + +I  ++T C++ D   RP+F++L
Sbjct:  625 AMAYLESIRIVHGHFTPNNILMDGEFHAKVC---------------------SPRGPSH----HAQLRYSAPESIVNNEFTHKSDAWAVATTVYEMAYQCRQRPYEELTNE---------QIVDNACALLDHQPNAVV---------------PLMPTVFNYEILQLLTRCFRVDQLERPTFERL 760          

Query: 2016 SQTWIEKALSRIPEIDANQINLEALVTEGEIGA-----FVSGRLGKSNIEILVARFKPNNFKIDSKSLFYRQCFAKLREDFSS-----HPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            SQ  I+    ++ EI  +Q+++   + EG+ G      + SG      + + V + + +    +          A+L ++  +     HPN+I +IG C +      N+   V+ +    ++   LK + + P  +D+       + +  LY+  Q+A  + YL+ +  VH+D++ RNC +G+   + ++DF +    +  DY  +    +            +P+ WM  EAI  G +S  SD+WSFGVT+WEI++  + +PY    NQ          +I    L+AN +            L +  H  PTN       I  +M +CW  +   RP+F ++ S L
Sbjct:  412 SQEPIDDNSYKVFEITPSQLSVREKIGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAER---------AQLEQEIRAVATFDHPNVIKLIGVCYM-----DNSLLAVFEYMVHGDLHELLK-VRVPPADHDM--GGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSYGSDYYKMLHRSW------------MPVRWMSKEAIEQGRFSEASDVWSFGVTLWEIWSFGR-QPYEGASNQ---------QVIE---LVANRH------------LLECPHNCPTN-------IYSLMVECWHENIERRPTFSEIRSRL 698          

Query:  129 CWFLITIIFLSSQLSANTET-SPRKDAD------------GYCATGILQDSHSI---RISASSVLRNDPDFGPESSRIVGLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKAN---PINKMQSHV--VAWKRKTDLMDHIVLLFKFRKVRQFQSLKIY 983
            CW  +T+I L+++    T   +P   A             G C   +  +S +I   +I+ASS   +  + GP+ +R+   +D     AWCP   V    TE+LQ++      ++ I TQGR   G   E+  +Y  +Y R   + W R+   +  E++P N +  +      +  + A+++R+ P S  +  VCLR  + GC +++G+  Y IP+G    +    I   D+ YDG +  +      G+G+L+D     K N    IN +      + W+  T L   + ++F+F  VR   ++ I+
Sbjct:   64 CWLTLTLILLANRFGMGTAVGTPETPAAVGSNGLLAEMPIGTCKQALGMESGAIADFQITASSA-HDMGNVGPQHARLK--IDN-NGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKKWIRWRSLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGCAWEEGIVSYSIPKG---MQRGMDIDLSDKTYDGYEEGDH--YVNGLGQLVDGQ-RGKDNFRADINGLGKGYEWIGWRNDTLLGRPVEIIFEFETVRNLSAVIIH 360          

Query:  129 CWFLITIIFLSSQLSANTET-SPRKDAD------------GYCATGILQDSHSI---RISASSVLRNDPDFGPESSRIVGLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNV-----IFTKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            CW  +T+I L+++    T   +P   A             G C   +  +S +I   +I+ASS   +  + GP+ +R+   +D     AWCP   V    TE+LQ++      ++ I TQGR   G   E+  +Y  +Y R   + W R+   +  E++P N +  +      +  + A+++R+ P S  +  VCLR  + GC +++G+  Y IP+G    +    I   D+ YDG  +        G+G+L+D            N + K     + W+  T L   + ++F+F  VR   ++ I+                V F         +      + +   +     ++ L     + + + LYF + W+ I+E+ F
Sbjct:   64 CWLTLTLILLANRFGMGTAVGTPETPAAVGSNGLLAEMPIGTCKQALGMESGAIADFQITASSA-HDMGNVGPQHARLK--IDN-NGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKKWIRWRSLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGCAWEEGIVSYSIPKG---MQRGMDIDLSDKTYDG--YEEGDHYVNGLGQLVDGQRGKDNFRADINGLGK-GYEWIGWRNDTLLGRPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFVHAKVFFSIGGRHFSGEPVQFSYMPDLVLDHARDVTIKLHHRLGRYVQLHLYFAARWMMISEITF 437          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFA--IGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + +L ++  VH+D++ R+C IG    + +      I    +  DY  +  F     G Q      +P+ WM WE++++G ++TKSD+WSF V +WEI T  + +PY  L +++         +I N  LI  +                 +HE    P +  ++I D+M +CW+ D + RPSF+++H  L
Sbjct:  877 ASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGF----TGRQSQP---MPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKS---------VIENIGLIYRDYK---------------MHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLYL 1038          

Query:  129 CWFLITIIFLSSQLSANTET-SPRKDAD------------GYCATGILQDSHSI---RISASSVLRNDPDFGPESSRIVGLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNV-----IFTKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            CW  +T+I L+++    T   +P   A             G C   +  +S +I   +I+ASS   +  + GP+ +R+   +D     AWCP   V    TE+LQ++      ++ I TQGR   G   E+  +Y  +Y R   + W R+   +  E++P N +  +      +  + A+++R+ P S  +  VCLR  + GC +++G+  Y IP+G    +    I   D+ YDG  +        G+G+L+D            N + K     + W+  T L   + ++F+F  VR   ++ I+                V F         +      + +   +     ++ L     + + + LYF + W+ I+E+ F
Sbjct:   64 CWLTLTLILLANRFGMGTAVGTPETPAAVGSNGLLAEMPIGTCKQALGMESGAIADFQITASSA-HDMGNVGPQHARLK--IDN-NGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKKWIRWRSLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGCAWEEGIVSYSIPKG---MQRGMDIDLSDKTYDG--YEEGDHYVNGLGQLVDGQRGKDNFRADINGLGK-GYEWIGWRNDTLLGRPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFVHAKVFFSIGGRHFSGEPVQFSYMPDLVLDHARDVTIKLHHRLGRYVQLHLYFAARWMMISEITF 437          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFA--IGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + +L ++  VH+D++ R+C IG    + +      I    +  DY  +  F     G Q      +P+ WM WE++++G ++TKSD+WSF V +WEI T  + +PY  L +++         +I N  LI  +                 +HE    P +  ++I D+M +CW+ D + RPSF+++H  L
Sbjct:  877 ASGMKHLEQMNFVHRDLATRSCIIGPELCVKVCSIGTVINRSAYASDYCQLEGF----TGRQSQP---MPIRWMAWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKS---------VIENIGLIYRDYK---------------MHELLPMPPNCPREIYDLMCECWQRDESSRPSFREIHLYL 1038          

Query:  138 LITIIFLSSQLSANTETSPRKDADGYCATGILQDSHSI---RISASSVLRNDPDF-GPESSRIVGLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQSHV-------VAWKRKTD--LMDHIVLLFKFRKVRQFQSLKIY----FTKYHLYRFDTAK---SLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            L T++  S  L  N  T+   D    C   +  +S  I   +I+ASS   +D  F GP+ +R+    D     AWCP   V N   E+LQ++   T  IT I TQGR   G   E+  +Y  +Y R     W R+ + +  E++P N +  +      +  + A++IRI P    +  VCLR  + GC +++G+  Y IP+G    +    +   D+ YDG +  +      G+G+L+D     K     +   H        + W+  T   L   + ++F+F  VR F ++ ++    FTK  +  F  AK   S+   +        S + ++I       +     ++ L     K + I LYF   WI ++E+ F
Sbjct:   53 LWTLVIASGCLMLNAPTTMAFDI-ATCNVPLGMESLLITDAQITASSA--HDMAFVGPQHARLKTDND---GGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYWRPGFDKWQRWKNIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVGCPWEEGIVSYSIPKG---VQRGMEVDLSDKTYDGNEQGDR--YVDGLGQLVDG---QKGKDNFRTDIHGFGKGYEWIGWRNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTK-DVQVFVHAKVFFSIGGRYFSGEPVQFSYMPDTI------MDHARDVTIKLHHRVGKYLKINLYFAVKWIMLSEISF 411          

Query:  138 LITIIFLSSQLSANTETSPRKDADGYCATGILQDSHSI---RISASSVLRNDPDF-GPESSRIVGLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQSHV-------VAWKRKTD--LMDHIVLLFKFRKVRQFQSLKIY----FTKYHLYRFDTAK---SLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            L T++  S  L  N  T+   D    C   +  +S  I   +I+ASS   +D  F GP+ +R+    D     AWCP   V N   E+LQ++   T  IT I TQGR   G   E+  +Y  +Y R     W R+ + +  E++P N +  +      +  + A++IRI P    +  VCLR  + GC +++G+  Y IP+G    +    +   D+ YDG +  +      G+G+L+D     K     +   H        + W+  T   L   + ++F+F  VR F ++ ++    FTK  +  F  AK   S+   +        S + ++I       +     ++ L     K + I LYF   WI ++E+ F
Sbjct:   53 LWTLVIASGCLMLNAPTTMAFDI-ATCNVPLGMESLLITDAQITASSA--HDMAFVGPQHARLKTDND---GGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYWRPGFDKWQRWKNIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRAEIVGCPWEEGIVSYSIPKG---VQRGMEVDLSDKTYDGNEQGDR--YVDGLGQLVDG---QKGKDNFRTDIHGFGKGYEWIGWRNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTK-DVQVFVHAKVFFSIGGRYFSGEPVQFSYMPDTI------MDHARDVTIKLHHRVGKYLKINLYFAVKWIMLSEISF 411          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            AWCP  PV  + +E+LQ++     F++ + TQGR +DG   EF  SY   Y R+    W  + D    E++  N +  +   +     ++A  +R  P++    +VCLR+ LYGC +KDG+  Y  P G  +    + + F+D  YDG K     +  GG+G+L D V+    F ++  +     +  V W R+T     + + F F K R F +++++    H         +  +F        ++   S+ VS+         SL L    ++++     F  +W+ I+E+ F
Sbjct:   76 AWCPAGPVFPSASEFLQVDLRKLHFLSLVGTQGRHADGLGREFARSYRLRYSRDGRH-WMTWKDRWGQEVVSGNENTYDIVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWKDGLKAYTAPLGHVMDLSGSLVNFNDSVYDGSKEGGVIF--GGLGQLCDGVLGGNDFMESKELRVWPGYDYVGWNRETLGQPTVDIEFHFEKTRIFHTMQVHSNNRHTQGVRVFSEVVCKFKASLLSPWAEPELSLQVSDLHDLSSRTISLPLGGRPAQILRCHFAFADNWLLISEISF 368          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHF----------HLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + +L+ L  VH+D++ RNC +G             H+ ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS + ++                 + +N         R + L++        P    + + ++M  CW  D  LRPSF  +HS L
Sbjct:  802 ASGMKFLASLNFVHRDLATRNCLVGGERGESEERGGERHIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSHMTDEQ----------------VIDNAGEFFRDQGRQVYLSR--------PAVCPQGLYELMLSCWNRDCKLRPSFAYIHSFL 966          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            AWCP  PV  + +E+LQ++     F++ + TQGR +DG   EF  SY   Y R+    W  + D    E++  N +  +   +     ++A  +R  P++    +VCLR+ LYGC +KDG+  Y  P G  +    + + F+D  YDG K     +  GG+G+L D V+    F ++  +     +  V W R+T     + + F F K R F +++++    H         +  +F        ++   S+ VS+         SL L    ++++     F  +W+ I+E+ F
Sbjct:   76 AWCPAGPVFPSASEFLQVDLRKLHFLSLVGTQGRHADGLGREFARSYRLRYSRDGRH-WMTWKDRWGQEVVSGNENTYDIVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWKDGLKAYTAPLGHVMDLSGSLVNFNDSVYDGSKEGGVIF--GGLGQLCDGVLGGNDFMESKELRVWPGYDYVGWNRETLGQPTVDIEFHFEKTRIFHTMQVHSNNRHTQGVRVFSEVVCKFKASLLSPWAEPELSLQVSDLHDLSSRTISLPLGGRPAQILRCHFAFADNWLLISEISF 368          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHF----------HLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + +L+ L  VH+D++ RNC +G             H+ ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS + ++                 + +N         R + L++        P    + + ++M  CW  D  LRPSF  +HS L
Sbjct:  802 ASGMKFLASLNFVHRDLATRNCLVGGERGESEERGGERHIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSHMTDEQ----------------VIDNAGEFFRDQGRQVYLSR--------PAVCPQGLYELMLSCWNRDCKLRPSFAYIHSFL 966          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            AWCP  PV  + +E+LQ++     F++ + TQGR +DG   EF  SY   Y R+    W  + D    E++  N +  +   +     ++A  +R  P++    +VCLR+ LYGC +KDG+  Y  P G  +    + + F+D  YDG K     +  GG+G+L D V+    F ++  +     +  V W R+T     + + F F K R F +++++    H         +  +F        ++   S+ VS+         SL L    ++++     F  +W+ I+E+ F
Sbjct:   76 AWCPAGPVFPSASEFLQVDLRKLHFLSLVGTQGRHADGLGREFARSYRLRYSRDGRH-WMTWKDRWGQEVVSGNENTYDIVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWKDGLKAYTAPLGHVMDLSGSLVNFNDSVYDGSKEGGVIF--GGLGQLCDGVLGGNDFMESKELRVWPGYDYVGWNRETLGQPTVDIEFHFEKTRIFHTMQVHSNNRHTQGVRVFSEVVCKFKASLLSPWAEPELSLQVSDLHDLSSRTISLPLGGRPAQILRCHFAFADNWLLISEISF 368          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHF----------HLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + +L+ L  VH+D++ RNC +G             H+ ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS + ++                 + +N         R + L++        P    + + ++M  CW  D  LRPSF  +HS L
Sbjct:  786 ASGMKFLASLNFVHRDLATRNCLVGGERGESEERGGERHIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSHMTDEQ----------------VIDNAGEFFRDQGRQVYLSR--------PAVCPQGLYELMLSCWNRDCKLRPSFAYIHSFL 950          

Query:  138 LITIIFLSSQLSANTETSPRKDADGYCATGILQDSHSIRISASSVLRNDPDFGPESSRIVGLVDVLTP-KAWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVS--NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD 1223
            L+ +++LS  + +       +   G     IL +     ISASS       +   ++   G +D      AWCP+ P       E+LQI+  S  FIT + TQGR  G  G EF  +Y   Y R+ S+ W  + + +  E+I  N +  +   +  E  ++A  +R +P+   + NVC+R+ LYGC++ DG+  Y  P G  +  +   I  +D  YDG    + T    G+G+L D +     FT ++  N    +  V W  ++    ++ ++F+F + R F ++K++       R  T + +   F  + +   + ++ S  +   NP+       ++ L    +  I  + YF   W+  +E+ F++D
Sbjct:   19 LLILLYLSGAVQSQVNPGVCRSPLGMSRGQILDED----ISASS------QWSESTAAKYGRLDCEEGDGAWCPEIPAEPENMKEFLQIDLRSLHFITLVGTQGRHAGGIGNEFAQTYKIKYSRDGSR-WISWRNRQGKEVIEGNRNAYDIVLKDLEPPIIARFVRFMPVIDHSMNVCMRVELYGCEWLDGLVSYNSPLGQQMSLNGQHIYLNDSVYDGAMSYSMT---EGLGQLTDGMCGLDDFTLSHVYNVWPGYDYVGWTNESFPNGYVEIMFEFDRTRNFTTMKVHCNNMFSRRVKTFQKVVCYFRSELDWEATPVSFSPVMDDVNPSAR---FVTVSLYNHMASAIKCQYYFSDIWMMFSEITFQSD 373          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIP 3044
            A  + YLS L  VH+D++ RNC +G++F + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+FGVT+WE+ T C+ +PYS L ++                 +  N         R + L Q        P      +  +M  CW  +   RPSFQ++H  L    P
Sbjct:  709 ASGMKYLSSLNFVHRDLATRNCLVGKNFTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTSSDVWAFGVTLWEMLTFCKEQPYSQLSDEQ----------------VIENTGEFFRDQRRQIYLPQ--------PPMCPDPVYKLMLSCWHRNTKERPSFQEIHHTLLECKP 868          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            AWCP  PV  + +E+LQ++     F++ + TQGR +DG   EF  SY   Y R+    W  + D    E++  N +  +   +     ++A  +R  P++    +VCLR+ LYGC +KDG+  Y  P G  +    + + F+D  YDG K     +  GG+G+L D V+    F ++  +     +  V W R+T     + + F F K R F +++++    H         +  +F        ++   S+ VS+         SL L    ++++     F  +W+ I+E+ F
Sbjct:   76 AWCPAGPVFPSASEFLQVDLRKLHFLSLVGTQGRHADGLGREFARSYRLRYSRDGRH-WMTWKDRWGQEVVSGNENTYDIVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWKDGLKAYTAPLGHVMDLSGSLVNFNDSVYDGSKEGGVIF--GGLGQLCDGVLGGNDFMESKELRVWPGYDYVGWNRETLGQPTVDIEFHFEKTRIFHTMQVHSNNRHTQGVRVFSEVVCKFKASLLSPWAEPELSLQVSDLHDLSSRTISLPLGGRPAQILRCHFAFADNWLLISEISF 368          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHF----------HLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + +L+ L  VH+D++ RNC +G             H+ ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS + ++                 + +N         R + L++        P    + + ++M  CW  D  LRPSF  +HS L
Sbjct:  748 ASGMKFLASLNFVHRDLATRNCLVGGERGESEERGGERHIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSHMTDEQ----------------VIDNAGEFFRDQGRQVYLSR--------PAVCPQGLYELMLSCWNRDCKLRPSFAYIHSFL 912          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDS-IFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITV--SNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDL-------PKDSSSIPDLY 1262
            AWCP+ PV     TE+LQI+     FIT + TQGR  G +G EF   +  +Y R+ ++ W  + +    +++  N +  +   +  E  +VA  +R +P++  + NVCLR+ LYGC + DG+  Y  P G   +  +  +I  +D  YDG    + T    G+G+L D V     FT  +  +    +  V W  ++    ++ ++F+F ++R F ++K++            K +   F  + NE   + I++++ +  +NP+       ++ L    ++ I    YF   W+  +E+ F++D         P   +S+P  Y
Sbjct:   68 AWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDGTR-WISWRNRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSGQQFLLPEGYAIYLNDTIYDGAIGYSMT---EGLGQLTDGVSGLDDFTLTHEYHMWPGYDYVGWSNESFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEWEANSISSTLVLDDANPSAR---YVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSDAAMYNNSMNPPQPASVPTTY 384          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSI-LPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTSKPLDE 3065
            A  + YLS L  VH+D++ RNC +G ++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+F VT+WE  T C+ +PYS + ++          +I N+     +    + LP                 P    +++  +M  CW+ +   RPSFQ+    +C  + +   L E
Sbjct:  691 ASGMKYLSSLNFVHRDLATRNCLVGRNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFAVTLWETLTFCREQPYSEMSDE---------QVIENTGEFFRDQGKQVYLP----------------KPNICPERVYKLMLSCWRRETKDRPSFQE----ICQSLQSESGLHE 853          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDS-IFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITV--SNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDL-------PKDSSSIPDLY 1262
            AWCP+ PV     TE+LQI+     FIT + TQGR  G +G EF   +  +Y R+ ++ W  + +    +++  N +  +   +  E  +VA  +R +P++  + NVCLR+ LYGC + DG+  Y  P G   +  +  +I  +D  YDG    + T    G+G+L D V     FT  +  +    +  V W  ++    ++ ++F+F ++R F ++K++            K +   F  + NE   + I++++ +  +NP+       ++ L    ++ I    YF   W+  +E+ F++D         P   +S+P  Y
Sbjct:   36 AWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDGTR-WISWRNRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSGQQFLLPEGYAIYLNDTIYDGAIGYSMT---EGLGQLTDGVSGLDDFTLTHEYHMWPGYDYVGWSNESFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEWEANSISSTLVLDDANPSAR---YVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSDAAMYNNSMNPPQPASVPTTY 352          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSI-LPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKL 3017
            A  + YLS L  VH+D++ RNC +G ++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+F VT+WE  T C+ +PYS + ++          +I N+     +    + LP                 P    +++  +M  CW+ +   RPSFQ++
Sbjct:  656 ASGMKYLSSLNFVHRDLATRNCLVGRNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFAVTLWETLTFCREQPYSEMSDE---------QVIENTGEFFRDQGKQVYLP----------------KPNICPERVYKLMLSCWRRETKDRPSFQEI 806          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDS-IFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITV--SNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDL-------PKDSSSIPDLY 1262
            AWCP+ PV     TE+LQI+     FIT + TQGR  G +G EF   +  +Y R+ ++ W  + +    +++  N +  +   +  E  +VA  +R +P++  + NVCLR+ LYGC + DG+  Y  P G   +  +  +I  +D  YDG    + T    G+G+L D V     FT  +  +    +  V W  ++    ++ ++F+F ++R F ++K++            K +   F  + NE   + I++++ +  +NP+       ++ L    ++ I    YF   W+  +E+ F++D         P   +S+P  Y
Sbjct:   36 AWCPEMPVDPEELTEFLQIDLRVLHFITLVGTQGRHAGGHGNEFAQMFKINYSRDGTR-WISWRNRHGRQVLDGNVNPYDIVLKDLEPPIVARFLRFIPVTDHSMNVCLRVELYGCVWLDGLVSYNAPSGQQFLLPEGYAIYLNDTIYDGAIGYSMT---EGLGQLTDGVSGLDDFTLTHEYHMWPGYDYVGWSNESFSNGYVEIVFEFDRIRNFTTMKVHCNNMFSKGVKIFKDVQCFFRSDANEWEANSISSTLVLDDANPSAR---YVTVQLHNHMARAIKCHYYFADSWMMFSEITFQSDAAMYNNSMNPPQPASVPTTY 352          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSI-LPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTSKPLDE 3065
            A  + YLS L  VH+D++ RNC +G ++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+F VT+WE  T C+ +PYS + ++          +I N+     +    + LP                 P    +++  +M  CW+ +   RPSFQ+    +C  + +   L E
Sbjct:  662 ASGMKYLSSLNFVHRDLATRNCLVGRNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFAVTLWETLTFCREQPYSEMSDE---------QVIENTGEFFRDQGKQVYLP----------------KPNICPERVYKLMLSCWRRETKDRPSFQE----ICQSLQSESGLHE 824          

Query: 2247 SHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            S P++I ++G CL     D +   ++  +    ++  FL   HL       +     +S  SLL+V  Q+   + YLS L  VH+D+++RNC +GE+F + ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WEI   C+ +PY  L ++         ++I N+  I  ++   I            +   P  P    + + ++M  CW  D   RPSFQ +H+LL
Sbjct:  713 SDPHIIRLLGACL-----DEDPLCMITEYMENGDLNQFLSSHHLDEGEESGAQCLPAISYPSLLHVAVQICSGMKYLSSLNFVHRDLASRNCLVGENFTIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEILMLCKEQPYGELSDE---------DVIENAGEIFRDSKKQIF-----------LFRPPPCP----QPLYELMLQCWSRDCRERPSFQDIHALL 932          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQS-----HVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEK-----NEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDL 1229
            AWCP  PV     E+LQ++  +  F+T + TQGR  G  G EF   Y   Y R+  + W ++ D    E+I  N +  ++  +     ++A  +R  P++    +VCLR+ LYGC ++DG+  Y  P G+ +   +  I  +D  YDG  F+      GG+G+L D VI       +K Q        V W        ++ + F+F  +R F  ++++            + +   F        + + ++ ++ ++ V +P+       ++ L+   ++++    YF S W+ ++E+ F +D L
Sbjct:   74 AWCPLGPVFPNYEEFLQVDLRNLHFLTLVGTQGRDGGGLGKEFARHYQLRYSRDGFK-WSQWRDRWGNEVIEGNENTHDSVLKDLGPPIIARYVRFYPMADRVMSVCLRVELYGCIWQDGLRSYTSPPGNVMSLPSMLINLNDSTYDG--FTVGGLQYGGLGQLTDGVIGADDFLQHKEQGVWPGYDYVGWMTSNFPKGYLEMEFEFDALRSFIYMRVHCNNMGSGGIQIFRRVDCYFKRSLHTPWDPQPVT-LSLALDVRDPSARS---VTIALQGRAARILRCHYYFSSQWLLLSEISFLSDIL 372          

Query: 2247 SHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            S P++I ++G CL     D +   ++  +    ++  FL   HL       +     +S  SLL+V  Q+   + YLS L  VH+D+++RNC +GE+F + ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WEI   C+ +PY  L ++         ++I N+  I  ++   I            +   P  P    + + ++M  CW  D   RPSFQ +H+LL
Sbjct:  679 SDPHIIRLLGACL-----DEDPLCMITEYMENGDLNQFLSSHHLDEGEESGAQCLPAISYPSLLHVAVQICSGMKYLSSLNFVHRDLASRNCLVGENFTIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEILMLCKEQPYGELSDE---------DVIENAGEIFRDSKKQIF-----------LFRPPPCP----QPLYELMLQCWSRDCRERPSFQDIHALL 898          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQS-----HVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEK-----NEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDL 1229
            AWCP  PV     E+LQ++  +  F+T + TQGR  G  G EF   Y   Y R+  + W ++ D    E+I  N +  ++  +     ++A  +R  P++    +VCLR+ LYGC ++DG+  Y  P G+ +   +  I  +D  YDG  F+      GG+G+L D VI       +K Q        V W        ++ + F+F  +R F  ++++            + +   F        + + ++ ++ ++ V +P+       ++ L+   ++++    YF S W+ ++E+ F +D L
Sbjct:   74 AWCPLGPVFPNYEEFLQVDLRNLHFLTLVGTQGRDGGGLGKEFARHYQLRYSRDGFK-WSQWRDRWGNEVIEGNENTHDSVLKDLGPPIIARYVRFYPMADRVMSVCLRVELYGCIWQDGLRSYTSPPGNVMSLPSMLINLNDSTYDG--FTVGGLQYGGLGQLTDGVIGADDFLQHKEQGVWPGYDYVGWMTSNFPKGYLEMEFEFDALRSFIYMRVHCNNMGSGGIQIFRRVDCYFKRSLHTPWDPQPVT-LSLALDVRDPSARS---VTIALQGRAARILRCHYYFSSQWLLLSEISFLSDIL 372          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILF-DDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITVS--NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD-DLPKDSSSIP 1253
            AWCP+ PV  +   E+LQI+  +  FIT + TQGR  G +G EF P Y  +Y R+ S+ W  + +    +++  N++  +   +  E  +VA  +R++P++  + NVC+R+ LYGC + DG+  Y  P G        SI++ +D  YDG    + T    G+G+L D V     FT+ +  +    +  V W+ ++     I ++F+F ++R F ++K++            K +   F  E +E   + +   + +   NP+       ++ L    +  I  + +F   W+  +E+ F++D  +  +S ++P
Sbjct:   71 AWCPEIPVQPDDLKEFLQIDLRTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGSR-WISWRNRHGKQVLDGNSNPYDVFLKDLEPPIVARFVRLIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMT---EGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGFIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPTAVYFPLVLDDVNPSAR---FVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSGALP 378          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + YLS L  VH+D++ RNC +G+++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+FGVT+WE FT CQ +PYS L ++                 +  N         R + L Q        P      +  +M  CW+ +   RPSFQ++H LL
Sbjct:  694 ASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ----------------VIENTGEFFRDQGRQIYLPQ--------PALCPDSVYKLMLSCWRRETKHRPSFQEIHLLL 848          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILF-DDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITVS--NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD-DLPKDSSSIP 1253
            AWCP+ PV  +   E+LQI+  +  FIT + TQGR  G +G EF P Y  +Y R+ S+ W  + +    +++  N++  +   +  E  +VA  +R++P++  + NVC+R+ LYGC + DG+  Y  P G        SI++ +D  YDG    + T    G+G+L D V     FT+ +  +    +  V W+ ++     I ++F+F ++R F ++K++            K +   F  E +E   + +   + +   NP+       ++ L    +  I  + +F   W+  +E+ F++D  +  +S ++P
Sbjct:   71 AWCPEIPVQPDDLKEFLQIDLRTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGSR-WISWRNRHGKQVLDGNSNPYDVFLKDLEPPIVARFVRLIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMT---EGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGFIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPTAVYFPLVLDDVNPSAR---FVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSGALP 378          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + YLS L  VH+D++ RNC +G+++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+FGVT+WE FT CQ +PYS L ++                 +  N         R + L Q        P      +  +M  CW+ +   RPSFQ++H LL
Sbjct:  694 ASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ----------------VIENTGEFFRDQGRQIYLPQ--------PALCPDSVYKLMLSCWRRETKHRPSFQEIHLLL 848          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILF-DDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITVS--NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD-DLPKDSSSIP 1253
            AWCP+ PV  +   E+LQI+  +  FIT + TQGR  G +G EF P Y  +Y R+ S+ W  + +    +++  N++  +   +  E  +VA  +R++P++  + NVC+R+ LYGC + DG+  Y  P G        SI++ +D  YDG    + T    G+G+L D V     FT+ +  +    +  V W+ ++     I ++F+F ++R F ++K++            K +   F  E +E   + +   + +   NP+       ++ L    +  I  + +F   W+  +E+ F++D  +  +S ++P
Sbjct:   71 AWCPEIPVQPDDLKEFLQIDLRTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGSR-WISWRNRHGKQVLDGNSNPYDVFLKDLEPPIVARFVRLIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMT---EGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGFIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPTAVYFPLVLDDVNPSAR---FVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSGALP 378          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + YLS L  VH+D++ RNC +G+++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+FGVT+WE FT CQ +PYS L ++                 +  N         R + L Q        P      +  +M  CW+ +   RPSFQ++H LL
Sbjct:  694 ASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ----------------VIENTGEFFRDQGRQIYLPQ--------PALCPDSVYKLMLSCWRRETKHRPSFQEIHLLL 848          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCN 3035
            A  + YL+ L  VH+D++ RNC +GE+F + ++DF +    +  DY  +              AV LP+ WM WE I+MG ++T SD+W+FGVT+WE+   C+ +P+  L ++          +I N+     +         R + L++        P    + + ++M  CW  +P  RP F +LH  L +
Sbjct:  712 ASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRV-----------QGRAV-LPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDE---------QVIENAGEFFRD-------QGRQVYLSR--------PPACPQTLYELMLRCWSREPEQRPPFAQLHRFLAD 868          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNP---TFND--EDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD 1223
            AWCP  PV     E+LQ++      +  + TQGR  G  G EF  SY   Y R+  + W  + D    E+I  N D      +     +VA  +R  P +    +VCLR+ LYGC ++DG+  Y  P G ++      +  +D  YDG  ++      GG+G+L D V+    F ++  +     +  V W  ++    ++ + F+F ++R FQ+++++    H         +   F    ++G +       V +    +  D      S+ L     + +  +  F   W+  +E+ F +D
Sbjct:   73 AWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRR-WMDWKDRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMQLSEVMVHLNDSTYDG--YTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWPGYDYVGWSNQSFPTGYVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRF----KRGPAMAWEGEPVRHALGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISD 369          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCN 3035
            A  + YL+ L  VH+D++ RNC +GE+F + ++DF +    +  DY  +              AV LP+ WM WE I+MG ++T SD+W+FGVT+WE+   C+ +P+  L ++          +I N+     +         R + L++        P    + + ++M  CW  +P  RP F +LH  L +
Sbjct:  749 ASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRV-----------QGRAV-LPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDE---------QVIENAGEFFRD-------QGRQVYLSR--------PPACPQTLYELMLRCWSREPEQRPPFAQLHRFLAD 905          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNP---TFND--EDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD 1223
            AWCP  PV     E+LQ++      +  + TQGR  G  G EF  SY   Y R+  + W  + D    E+I  N D      +     +VA  +R  P +    +VCLR+ LYGC ++DG+  Y  P G ++      +  +D  YDG  ++      GG+G+L D V+    F ++  +     +  V W  ++    ++ + F+F ++R FQ+++++    H         +   F    ++G +       V +    +  D      S+ L     + +  +  F   W+  +E+ F +D
Sbjct:   73 AWCPAGPVFPKEEEYLQVDLRRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRR-WMDWKDRWGQEVISGNEDPGGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMQLSEVMVHLNDSTYDG--YTAGGLQYGGLGQLADGVVGLDDFRQSQELRVWPGYDYVGWSNQSFPTGYVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPGGVECRF----KRGPAMAWEGEPVRHALGGSLGDPRARAISVPLGGHVGRFLQCRFLFAGPWLLFSEISFISD 369          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDL---FSLDLKRFRSKLIIIKLYF--KSDWIAINEVMFETD----DLPKDSSSIPDLYSTVNV 1277
            AWCP   +++   EWLQI FS    IT + TQGR D   G E+  ++   Y R S   W  Y D    E IPAN D  +A  +  +  ++A RIRIVP+S+    VC+R+ ++GC F D +  Y + +GD      + I + D +YDG   +N   L GG+G+L D  +      +N  +   V W+RK +   ++ L F+F ++R    + I+ +           S TV F   N K  S     +  +NP   + ++     + +    +K+  I+L F   SDW+ I+EV FE++    +L  D   IPD  S  +V
Sbjct:   67 AWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDDSLVFYNVDQGDL----QSGISYHDFSYDGN-LANSPHLTGGIGKLYDGEVGKNNVFVNHHK--WVGWRRKRN--GNVKLAFEFSELRNISGILIHTSNEFKKSAKAFSSATVLF-SINGKDFSDTI--VHFNNPEDTESEVPRWIRIPVNNRIAKVAKIRLNFGTDSDWLFISEVNFESNHTNIELLNDDVVIPDSVSYFSV 375          

Query: 2031 EKALSRIPEIDANQINLEALVTEGEIGAFVSGRLGKSNIEILVARFKPNNFKIDSKSLFYRQ--CFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTS 3050
            E   + +PEI  +++   + + +GE G     +L        VA  K +      +  F+R+      L+     HPN++ ++G C +           +  +    ++ +++ K   I  +  IS                QLA  L+YL     VH+D++ARNC +    ++ ++DF +    +  +Y  +       EG        LP+ WM WEA+++G +ST SD+W FGVTMWEIF+ C  KPYS + +          +++ N   +++           T  L Q++      P   SK   + +  CW  + + RPSF+ +H  L +L+ TS
Sbjct:  513 EVYCTTLPEIARDKLICVSRIGQGEFGEVDLCQLENRK----VAVKKLHGISQADEFSFHREIRVLGSLK-----HPNVVEVVGVCTI-----QKPILCIMEYMENGDLKSYILKNPTIQTSQCISIC-------------TQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYYKV-------EGK-----FVLPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDD---------DVVENLQSMSS-----------TGSLKQVLSRPRMCP---SKLYNEQILPCWNYESSRRPSFENVHLHLQSLVHTS 792          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILF-DDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITVS--NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD-DLPKDSSSIP 1253
            AWCP+ PV  +   E+LQI+  +  FIT + TQGR  G +G EF P Y  +Y R+ S+ W  + +    +++  N++  +   +  E  +VA  +R++P++  + NVC+R+ LYGC + DG+  Y  P G        SI++ +D  YDG    + T    G+G+L D V     FT+ +  +    +  V W+ ++     I ++F+F ++R F ++K++            K +   F  E +E   + +   + +   NP+       ++ L    +  I  + +F   W+  +E+ F++D  +  +S ++P
Sbjct:   71 AWCPEIPVQPDDLKEFLQIDLRTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGSR-WISWRNRHGKQVLDGNSNPYDVFLKDLEPPIVARFVRLIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMT---EGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGFIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPTAVYFPLVLDDVNPSAR---FVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSGALP 378          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + YLS L  VH+D++ RNC +G+++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+FGVT+WE FT CQ +PYS L ++                 +  N         R + L Q        P      +  +M  CW+ +   RPSFQ++H LL
Sbjct:  694 ASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQ----------------VIENTGEFFRDQGRQIYLPQ--------PALCPDSVYKLMLSCWRRETKHRPSFQEIHLLL 848          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILF-DDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFL-EKNEKGISQITNSITVS--NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETD 1223
            AWCP+ PV  +   E+LQI+  +  FIT + TQGR  G +G EF P Y  +Y R+ ++ W  + +    +++  N++  +   +  E  +VA  +R +P++  + NVC+R+ LYGC + DG+  Y  P G        SI++ +D  YDG    + T    G+G+L D V     FT+ +  +    +  V W+ ++    +I ++F+F ++R F ++K++            K +   F  E +E   + I+  + +   NP+       ++ L    +  I  + +F   W+  +E+ F++D
Sbjct:   71 AWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTR-WISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMT---EGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSAR---FVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSD 367          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNS-MLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            A  + YLS L  VH+D++ RNC +G+++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+FGVT+WE FT CQ +PYS L ++          +I N+     +    + LP                 P      +  +M  CW+ D   RPSFQ++H LL
Sbjct:  695 ASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDE---------QVIENTGEFFRDQGRQTYLP----------------QPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849          

Query:  141 ITIIFLSSQLSANTETSPRKDADGYCATGILQ-DSHSIRISASSVLRNDPDFGPESSRIVGLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPI--NKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            I ++ L+   +  T T  R D  G  A G+   D    +I+ASS   +    GP+++R   L   L   AWCP   +++   E+LQ+  + T  IT + TQGR  +G   EF   Y  DY R  SQ W RY +      +  N D      +  +  +VA+RIR VP S     VC+R  ++GC  +   +   +P G  +     ++ F D  ++  +   E+ ++ G+G L D  +  +A+P   N+M +  + W R T     I +LF+F +V  F  + +      +   D   S       K     SQI++S   S    +    F + L     + + I + F SDW+ + EV F
Sbjct:    3 IALVLLAIYGTTTTNTL-RIDQCGENALGMQNGDIADSQITASSSF-DKQSVGPQNAR---LHSELASGAWCPKPQINSKSYEFLQVTLNDTFLITSVETQGRYGNGTGREFASHYMIDYLRPGSQ-WIRYKNRTGHVYMDGNFDTTTPVIRVLDPPIVASRIRFVPSSKNTRTVCMRAEIHGCKHEGVTYYSTVPDGSRL----DTLDFKDSMFEDSQIYTESGIKRGLGLLTDGFV-AQASPFEKNQMNNSWIGWNRDTT-DGRITILFEFEEVHNFTDVVLATFGNRIDGIDVIFSQD----GKTFPLFSQISSSERQSLNNTSRRYDFRVPLHNRAGRKVRISIKFSSDWMFLTEVHF 348          

Query: 2058 IDANQINLEALVTEGEIGAFVSGRLGK---SNIEILVARFKPNNFKIDSKSLFYRQCFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLK--KLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPT 3047
            ID N ++L  ++ EGE G+ + GRL +   +  ++ V   K +NF       F  +  A   +DF  HPN+I ++G C+     + ++  I    P  + V+ F+K   LH     + +  A  +V    LL  +  +A  + YLS    +H+D++ARNC + +   + ++DF +  + +  DY             +      +P+ W+  E++    Y+TKSD+W+FGVTMWEI T   M PY                       + N+     L + + L       + P N LD   ++ DIM+ CW+++P  RP+F +L   L  L+ +
Sbjct:   40 IDRNALSLGKVLGEGEFGSVMEGRLSQPEGTPQKVAVKTMKLDNFSHREIEEFLSE--AACIKDFD-HPNVIKLLGVCI-----ELSSQQI----PKPMVVLPFMKYGDLHSFLLRSRLEMAPQFVPLQMLLKFMVDIALGMEYLSSRQFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYY------------RQGRIAKMPVKWIAIESLADRVYTTKSDVWAFGVTMWEIATR-GMTPYPG---------------------VQNHEIYEYLFHGQRL-------KKPENCLD---ELYDIMSSCWRAEPADRPTFSQLKVHLEKLLES 318          

Query:  129 CWFLITIIFLSSQLSANTETSPR-----KDADGYCATGILQDSHSI---RISASSVLRNDPDFGPESSRIV---GLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSIN-TNVCLRIRLYGCDFKDGVFEYQIPRGD------SIFRDNTSI--LFDDENYDGQKFSNETWLQGGMGRLMDNVIF-------TKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIY 983
            CW  +  I  S  L+ NT  + +        D  CA  ++    +      S+SSV +N  DF P  +R+    G  +  +  AWCP+  V +   EW+Q EFS    I+ IFT GR DGN  E++P++   YQRE +  WY +  +    ++ AN D RN A    +S ++A RIRI P S  +   VCLR  LYGCDF DGV  Y +P+GD       +F    SI   F D  YDGQ   +E  L GG+G+LMDNV +       + ++P  +   H + W   +     + +LFKF +VR F  L+I+
Sbjct:    7 CWITLLFILCSFILTVNTYKAEQIIRRGPGQDPQCADPLINSIDTFPDTSFSSSSVWKNATDFQPFRARLTEVYGSSEHTSGYAWCPNTHVEDGLREWIQAEFSHLVIISVIFTAGRGDGNVKEYMPNFVLRYQREDNGVWYEHVKSDGTRVLKANNDPRNIARTTLDSVVIAKRIRIYPYSHRSKQQVCLRFALYGCDFPDGVISYSMPQGDIVTYGRQLFGSPYSIPQSFQDLTYDGQLIESENQLIGGIGQLMDNVAYLGNVSQHSDSHP-TQPGFHFIGWHIPS---KDLRILFKFDEVRNFIWLRIF 314          

Query:  258 SASSVLRNDPDFGPESSRIVGLV---DVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTN-VCLRIRLYGCDFKDGVFEYQIPRGDSIFRDN---TSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIY----------FTKYHLYRF--DTA------KSLT-------VEFLEKNEKGISQITNSITVS------NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            SASSV +N P+F P  +R+  L    D    +AWCP+  V     EW+Q++F     I  IFT GR DGN  E++P++   YQRE    WY +    +G +I  N D RN A   F+  +VA RIRI P S+ + + +CL+  L GC F DG+ EY    G      +    SI F D   D  K        GG+G+L+DN       T+    +   +H V W+R  +   H+ L FKF ++R F  L I+           + Y    F  D A      KSLT       V+  E+++       NS + S      NP ++   + S+ L+   ++ + +KL+   DW+ I+EV+F
Sbjct:   13 SASSVRQNLPEFRPYHARLTNLYPGKDHAGGRAWCPNSTVQTAMNEWIQVDFPHLNIIRTIFTTGRGDGNVAEYMPAFILHYQREDGGPWYEHTTRDSGRVIQGNIDPRNTARHTFDPAVVARRIRIYPYSAKSQHPICLQFALKGCPFPDGITEYLATEGSHGHLGSDRYQSIDFRDSTNDADKALGPRGAPGGLGKLVDNAAHLGNITQDVYDSPANNHFVGWERSKN--SHVWLDFKFDRLRNFSRLLIFTFESSRLQVGLSNYTTIDFAGDAALSSIEKKSLTVLLSLDKVDLEERSDASWRDAVNSRSSSRVTVFRNPLWDGAVVVSIPLQGHIAQEVSMKLFHSKDWLLISEVLF 371          

Query:  258 SASSVLRNDPDFGPESSRIVGLVDVLTPK------AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINT-NVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSIL---------------FDDENYDGQKFSNETWLQGGMGRLMDNVIF----TKANPINKMQS--HVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIY 983
            SASSVL+N  DF P  +R   L DV   K      AWCP+  V     EW+Q EFS    I  IFT GR DGN  EF+PS+ F YQRE   TWY +       ++ AN+D RN A    +S ++A R+RI P S   + +VCLR  LYGC F DGV  Y IP+G    R  TS                   D +YDGQ       L  G+G+LMDNV F    T+ + +   Q   H V W +       I L+FKF   R+F  ++++
Sbjct:   57 SASSVLQNKTDFQPYQAR---LTDVYGSKEHTSGYAWCPNSMVDEMLREWIQAEFSDLVIIKSIFTAGRGDGNVKEFMPSFVFKYQREDGGTWYEHVKRDGARILKANSDPRNLARATLDSVVIAKRVRIYPYSRKGSRDVCLRFALYGCKFPDGVVSYTIPQGG--LRTQTSFRSLALGDPLEPVVARHLKDLSYDGQIIPTTYQLTDGLGQLMDNVAFLGNLTRESDLYPSQPGFHFVGWPQGE--QSEIQLIFKFDTTRRFTWIRLF 319          

Query:  129 CWFLITIIFLSSQL-SANTETSPR-----KDADGYCATGILQDSHS---IRISASSVLRNDPDFGPESSRIV---GLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSIN-TNVCLRIRLYGCDFKDGVFEYQIPRGDSI-------FRDNTSIL---FDDENYDGQKFSNETWLQGGMGRLMDNVIF----TKANPINKMQS--HVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIY 983
            C   IT+IF+S  +  ANT  + +        D  CA  +++   +      S+SSV +N  DF P  +R+    G  +  +  AWCP+  V +   EW+Q EFS    I+ IFT GR DGN  E++P++   YQRE +  WY +  T    ++ AN D RN A    +S ++A RIRI P S  +   VCLR  LYGC+F DGV  Y +P+GD+I       F    S +   F D  YDGQ    E  L GG+G+LMDN+ +    T+ +  +  Q   H + W      +    +LFKF +VR F  L+I+
Sbjct:    5 CKGWITLIFMSLFIWRANTYKAEQIIRRGPGQDPQCADPLIKSVDTFPDTSFSSSSVWKNATDFQPFRARLTEVYGSNEHTSGYAWCPNTHVEDGLREWIQAEFSHLVIISVIFTAGRGDGNVKEYMPNFVLRYQREDNGVWYEHVKTDGTRVLKANNDPRNIARTTLDSVVIAKRIRIYPYSHRSRQQVCLRFALYGCNFPDGVISYSMPQGDTITYGRQLLFGSPYSTIPQNFQDLTYDGQLIELENQLVGGIGQLMDNIAYLGNVTQHSDSHPAQPGFHFIGWNVPNKSLR---ILFKFDEVRTFIWLRIF 315          

Query:  258 SASSVLRNDPDFGPESSRIVGLVDVLTPK------AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINT-NVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSIL---------------FDDENYDGQKFSNETWLQGGMGRLMDNVIF----TKANPINKMQS--HVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIY 983
            SASSVL+N  DF P  +R   L DV   K      AWCP+  V     EW+Q EFS    I  IFT GR DGN  EF+PS+ F YQRE   TWY +       ++ AN+D RN A    +S ++A R+RI P S   + +VCLR  LYGC F DGV  Y IP+G    R  TS                   D +YDGQ       L  G+G+LMDNV F    T+ + +   Q   H V W +       I L+FKF   R+F  ++++
Sbjct:   57 SASSVLQNKTDFQPYQAR---LTDVYGSKEHTSGYAWCPNSMVDEMLREWIQAEFSDLVIIKSIFTAGRGDGNVKEFMPSFVFKYQREDGGTWYEHVKRDGARILKANSDPRNLARATLDSVVIAKRVRIYPYSRKGSRDVCLRFALYGCKFPDGVVSYTIPQGG--LRSQTSFRSPALGDPLEPVVARHLKDLSYDGQIIPTTYQLTDGLGQLMDNVAFLGNLTRESDLYPSQPGFHFVGWPQGE--QSEIQLIFKFDTTRRFTWIRLF 319          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGRSDGNYG-EFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVS--NPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDLPKDSSSIP 1253
            AWCP+ P       E+LQI+  S  FIT + TQGR  G  G EF  +Y   Y R+ S+ W  + +    ++I  N +  +   Q  +  ++A  +R +P+   + NVC+R+ LYGC++ DG+  Y  P G  +   +  I  +D  YDG    + T    G+G+L D +     FT ++  N    +  V W  ++    ++ ++F+F + R F ++K++       R  T + +   F  +++   + ++ S  V   NP+       ++ L    +  I  + YF   W+  +E+ F++D    +++ IP
Sbjct:   79 AWCPEIPGEPENMKEFLQIDLRSLHFITLVGTQGRHAGGIGNEFAQTYKIKYSRDGSR-WISWRNRHGKQVIEGNRNAYDVVLQDLQPPIIARFVRFMPVIDHSMNVCMRVELYGCEWLDGLVSYNAPLGQKMILHSQPIYLNDSVYDGAMSYSMT---EGLGQLTDGMCGLDDFTFSHVYNVWPGYDYVGWTNESFPNGYVEIMFEFDRTRNFTTMKVHCNNMFSQRVKTFQKVVCYFRSESDWEPTPVSFSPVVDDVNPSAR---FVTVSLNNHMASAIKCQYYFSDMWMMFSEITFQSDTAMYNTTLIP 383          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSI-LPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIP 3044
            A  + YLS L  VH+D++ RNC +G+++ + ++DF +    +  DY  I+                LP+ WM WE+I++G ++T SD+W+FGVT+WE  T C+ +PYS L ++          +I N+     +    I LP            + P  P  + K    +M  CW  +   RPSFQ++H +L    P
Sbjct:  709 ASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETLTFCKEQPYSQLSDE---------QVIENTGEFFRDQRRQIYLP------------QPPLCPDPAYK----LMLSCWNRNAKERPSFQEIHQVLLECKP 868          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLY--FKSDWIAINEVMFETDDLPKDSSSI 1250
            AWCP   V  + +E+LQ+      F++ + TQGR +DG+  EF  SY   Y R+  Q W  + D    E+I  N +  +   +     ++A  +R  P++    +VCLR+ LYGC + DG+  Y  P G  +    + I  +D  YDG   +    L GG+G+L D V+    F ++  +     +  V W R+      + + F F K R F  ++++    H         +  EF        ++    + V      D    S+DL        I++ +  F   W+ I+E+ F ++  P + SS+
Sbjct:   76 AWCPAGAVFPSGSEFLQVNLHKLHFLSLVGTQGRHADGHGREFARSYRLRYSRDGRQ-WITWKDRWGQEVISGNENTYDVVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYAAPMGHVMHLSGSPIYLNDSIYDGSIEAGT--LFGGLGQLCDGVLGGDDFMESKELRVWPGYDYVGWSREALGQPTVDIEFHFEKTRIFHVMQVHSNNRHTQGVRVFSEVVCEFKASLLDHWTEPALKLRVPLEDLKDPSSRSVDLPLGGRPAQILRCHFAFADRWLLISEISFNSE--PFEGSSV 380          

Query: 2253 PNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHF----------HLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCN 3035
            PN+I ++G C+      S+   +V  +    ++  +L +  L+ KT  +    +    + +    +  +G + +L+ L  VH+D++ RNC +G             H+ ++DF +    +  DY  I+             AV LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS + ++                 + +N       + R + LT+        P    + + ++M  CW  D  LRPSF  +HS L  
Sbjct:  739 PNIIRLLGVCV-----SSDPLCMVTEYMESGDLNQYLSQRVLLDKTGPLHNTPTISYPALISMASQIASG-MKFLASLNFVHRDLATRNCLVGGERGDGEDRMGERHIKIADFGMSRNLYAGDYYRIQ-----------GRAV-LPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSHMTDEQ----------------VIDNAGEFFRDHGRQIYLTR--------PAVCPQGLYELMLSCWNRDCKLRPSFTHMHSFLAE 967          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLY--FKSDWIAINEVMFETDDLPKDSSSI 1250
            AWCP   V  + +E+LQ+      F++ + TQGR +DG+  EF  SY   Y R+  Q W  + D    E+I  N +  +   +     ++A  +R  P++    +VCLR+ LYGC + DG+  Y  P G  +    + I  +D  YDG   +    L GG+G+L D V+    F ++  +     +  V W R+      + + F F K R F  ++++    H         +  EF        ++    + V      D    S+DL        I++ +  F   W+ I+E+ F ++  P + SS+
Sbjct:   95 AWCPAGAVFPSGSEFLQVNLHKLHFLSLVGTQGRHADGHGREFARSYRLRYSRDGRQ-WITWKDRWGQEVISGNENTYDVVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYAAPMGHVMHLSGSPIYLNDSIYDGSIEAGT--LFGGLGQLCDGVLGGDDFMESKELRVWPGYDYVGWSREALGQPTVDIEFHFEKTRIFHVMQVHSNNRHTQGVRVFSEVVCEFKASLLDHWTEPALKLRVPLEDLKDPSSRSVDLPLGGRPAQILRCHFAFADRWLLISEISFNSE--PFEGSSV 399          

Query: 2253 PNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHF----------HLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            PN+I ++G C+      S+   +V  +    ++  +L +  L+ KT  +    +    + +    +  +G + +L+ L  VH+D++ RNC +G             H+ ++DF +    +  DY  I+             AV LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS + ++                 + +N       + R + LT+        P    + + ++M  CW  D  LRPSF  +HS L
Sbjct:  758 PNIIRLLGVCV-----SSDPLCMVTEYMESGDLNQYLSQRVLLDKTGPLHNTPTISYPALISMASQIASG-MKFLASLNFVHRDLATRNCLVGGERGDGEDRMGERHIKIADFGMSRNLYAGDYYRIQ-----------GRAV-LPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSHMTDEQ----------------VIDNAGEFFRDHGRQIYLTR--------PAVCPQGLYELMLSCWNRDCKLRPSFTHMHSFL 984          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLY--FKSDWIAINEVMFETDDLPKDSSSI 1250
            AWCP   V  + +E+LQ+      F++ + TQGR +DG+  EF  SY   Y R+  Q W  + D    E+I  N +  +   +     ++A  +R  P++    +VCLR+ LYGC + DG+  Y  P G  +    + I  +D  YDG   +    L GG+G+L D V+    F ++  +     +  V W R+      + + F F K R F  ++++    H         +  EF        ++    + V      D    S+DL        I++ +  F   W+ I+E+ F ++  P + SS+
Sbjct:   76 AWCPAGAVFPSGSEFLQVNLHKLHFLSLVGTQGRHADGHGREFARSYRLRYSRDGRQ-WITWKDRWGQEVISGNENTYDVVLKDLGPPIIARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYAAPMGHVMHLSGSPIYLNDSIYDGSIEAGT--LFGGLGQLCDGVLGGDDFMESKELRVWPGYDYVGWSREALGQPTVDIEFHFEKTRIFHVMQVHSNNRHTQGVRVFSEVVCEFKASLLDHWTEPALKLRVPLEDLKDPSSRSVDLPLGGRPAQILRCHFAFADRWLLISEISFNSE--PFEGSSV 380          

Query: 2253 PNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHF----------HLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCN 3035
            PN+I ++G C+      S+   +V  +    ++  +L +  L+ KT  +    +    + +    +  +G + +L+ L  VH+D++ RNC +G             H+ ++DF +    +  DY  I+             AV LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS + ++                 + +N       + R + LT+        P    + + ++M  CW  D  LRPSF  +HS L  
Sbjct:  701 PNIIRLLGVCV-----SSDPLCMVTEYMESGDLNQYLSQRVLLDKTGPLHNTPTISYPALISMASQIASG-MKFLASLNFVHRDLATRNCLVGGERGDGEDRMGERHIKIADFGMSRNLYAGDYYRIQ-----------GRAV-LPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSHMTDEQ----------------VIDNAGEFFRDHGRQIYLTR--------PAVCPQGLYELMLSCWNRDCKLRPSFTHMHSFLAE 929          

Query:  345 AWCPDKPVH-NTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDLPKDSSSIP 1253
            AWCPD      +  E+LQI+  +  F+T + TQGR +DG   EF  SY   Y R+  + W  ++D   G++I  N +      +  E  ++A  +R +P+S  +  VC+R+ LYGC++ DG+  Y  P G  +   N  +  +D  YDG   + +  +  G+G+L D       FT++        +  V W   +     + ++F+F +VR F S+K++    +       +     F  +++     ++      N T       ++ L    +  I  +  F   W+  +E+ F++     ++S IP
Sbjct:   67 AWCPDVVAEAKSLKEFLQIDLRTLHFVTLVGTQGRHADGMGNEFAQSYRIKYSRDGVR-WVSWHDRNGGQVIDGNKNPYEVVLKDLEPPIIARFVRFMPVSDPSMTVCMRVELYGCEWLDGLVSYSAPVGQEMTFQNLHVYLNDTVYDG---TVDHSMTEGLGQLTDGSWGLDNFTQSQVYGVWPGYDYVGWTNASFPSGSVEMVFEFDRVRNFTSMKVHCNNMYTSGVRAFQQAVCYFRSESDWEARPVSFKPEADN-TNTSARFVTVALGHRMASAIKCRFAFSDAWMMFSEIAFQSGTAVYNTSLIP 371          

Query: 2253 PNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNS-MLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            PN+I ++  C+     +S+   ++  +    ++  FL +  L     +     S +S S+L+ +  Q+A  + YLS L  VH+D++ RNC +G ++ + ++DF +    ++ DY  I+                LP+ WM WE+I++G ++  SD+W+FGVT+WE  T C+ +PYS L +           +I N+     + N    LP                 P      +  +M  CW+ +   RPSFQ +HS L
Sbjct:  627 PNIIRLLAVCV-----ESDPLCMITEYMENGDLNKFLSRHKLQDSGEEQKDTSSTISYSTLIRMATQIASGMKYLSSLNFVHRDLATRNCLVGTNYTIKIADFGMSRNLYRGDYYRIQ------------GRAVLPIRWMSWESILLGKFTMASDVWAFGVTLWETLTLCKEQPYSQLSDD---------QVIENTGEFFRDQNKQVYLP----------------RPACCPDAVHSLMQSCWRRNAKERPSFQHIHSTL 844          

Query: 2463 ALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQ 2795
             ++YLS L  VH+D++ RNC +GEH  + ++DF +    +  DY  I+                LP+ WM WE+I++G ++  SD+W+FGVT+WE+ T C+ +PY AL ++
Sbjct:   95 GMAYLSSLNFVHRDLATRNCLVGEHHTIKIADFGMSRNLYSGDYYRIQ------------GRAVLPIRWMAWESILLGKFTPASDVWAFGVTLWEMLTLCREQPYGALTDE 193          

Query: 2190 DSKSLFYRQCFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLH------------LIPKTND---ISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNL 3038
            D ++ F+R+  A L  +F+ HPN++ ++G C +G         +++ F    ++  +L++                P ++    +S  C+     +        A  ++YL+E   VH+D++ RNC +G    + +SDF +    +  DY          + N++ A   +P+ WMP E+I    Y+++SD+W+FGV +WEIF+   ++PY  + ++       +   +R+  ++A        P+   LDL                   ++M  CW   P  RPSF  +  +L  +
Sbjct:    3 DMQANFHRE--AALMAEFT-HPNIVKLLGVCAVG-----KPFCLLFEFMPHGDLNEYLRRCSSEAGLAASSPPARAPTSSGSEPVSLCCADKLFVATQV-----AAGMAYLAERKFVHRDLATRNCLVGNRLVVKISDFGLSQSIYAADYY---------KANENDA---IPIRWMPPESIFYNRYTSESDVWAFGVVLWEIFSH-GLQPYFGMSHEE------VIYFVRDGNVLA-------CPDGCPLDLY------------------NLMRLCWAHAPADRPSFASVQHVLARM 243          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSF-QKLHSLLCNLIPT 3047
            A  ++YL+    VH+D++ARNC + E F + + DF +  + ++ DY             +      LP+ WM  E++  G ++T SD+WSFGV +WEI T+ + +PY  L N+      ++  ++   +L        +LP              P  P    +++++++  CW+ +P +RP+F + L  L  +L P+
Sbjct:  143 ADGMAYLNAKKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYY------------RKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATQAE-QPYQGLSNEQ-----VLKFVMDGGLL--------VLP--------------PACP----ERLQELIRKCWQYNPRMRPTFLEILDGLAPDLHPS 296          

Query: 2055 EIDANQINLEALVTEGEIGAFVSGRL---GKSNIEILVARFKPNNFKIDSKSLFYRQCFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQ 2795
            EID + I +E +V  GE G    GRL   GK    + +   K    +   +      C A +   F  HPN+I      L GV+  S    IV  +    ++ +FL+K       ND  F         L+ +++ +A  + YLS++  VH+D++ARN  +  +    +SDF +            R+   + E    +    +P+ W   EAI    +++ SD+WS+G+ MWE+ +  + +PY  + NQ
Sbjct:  581 EIDVSYIKIEGVVGAGEFGEVCRGRLRLPGKGEASVAIKTLKAGYTEEQRRDFL---CEASIMGQFD-HPNIIR-----LEGVITKSIPVMIVTEYMENGSLDSFLRK-------NDGQFT-----SIQLVGMLRGIAAGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLS-----------RVLEDDPEAAYTAKGGRIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGE-RPYWDMSNQ 797          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSF-QKLHSLLCNLIPT 3047
            A  ++YL+    VH+D++ARNC + E F + + DF +  + ++ DY             +      LP+ WM  E++  G ++T SD+WSFGV +WEI T+ + +PY  L N+      ++  ++   +L        +LP              P  P    +++++++  CW+ +P +RP+F + L  L  +L P+
Sbjct:  182 ADGMAYLNAKKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYY------------RKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATQAE-QPYQGLSNEQ-----VLKFVMDGGLL--------VLP--------------PACP----ERLQELIRKCWQYNPRMRPTFLEILDGLAPDLHPS 335          

Query: 2463 ALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFT 2756
             ++YL +  I+H+D+   N  I     + ++DF I            +L P N + N+  A++   +FWM  E +     + K+DIWS G  + E+FT
Sbjct:  566 GVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISK----------KLSPLNKKQNKR-ASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT 652          

Query: 2055 EIDANQINLEALVTEGEIGAFVSGRL---GKSNIEILVARFKPNNFKIDSKSLFYRQCFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNL 3038
            EI  +++ L+  + EGE G  + G L    ++  ++ +   K +  + D K +       K       H N++S+IG C LG+        I+  F +   ++  L++   I  +   +   S +S   LL +    A  + ++S    VH+D++ RN  + E     ++DF +  + + D          N +G +      LPL WM  E+++   Y+T+SDIWSFGV MWE+++   M PYSA          ++PN +  SML++    S                  P  P    ++I D+M  CW ++P +RPSF KL ++L +L
Sbjct:    2 EIPRDRVVLKDKLGEGEFGIVMEGELLIEEEAPRKVAIKMLKSDADRTDHKDMLRELDMFK---GIGQHENVVSLIGACTLGM-----PLYIITEFIAGGTLLELLRESRCITSSYVNANLVSKLSGKDLLKLALGAARGMRHISGNRFVHRDLATRNVLVTEDLTAKITDFGLSRDIYSDG------IYLNAKGGK------LPLKWMAPESLLDYVYTTQSDIWSFGVLMWEVWSFGAM-PYSA----------VVPNELL-SMLMSGFRLS----------------RPPLCP----EEIYDVMMSCWNAEPEVRPSFAKLCTVLESL 280          

Query: 2055 EIDANQINLEALVTEGEIG-AFVSGRLGKSNIEILVARFKPNNFKIDSKSLFYRQCFAKLR--EDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLI------PKTN--DISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENP--TNPLDSSKQIRDIMTDCWKSDPTLRPSFQKL 3017
            E   ++I L  +V  G  G  F++  +G SN +  V R      K ++    YR   ++L+       H N+++++G C  G   D     ++  +    N++ FL+K   +      P T   D +F       + L+    Q++ A+ +L+    VH+D++ARN  +GE++ + ++DF +  + +K+++               + A  LP+ WM  EA++   Y+  SD+WSFGV +WEIFT                                  +P   LP N   ++ Q + E      P D  +++ D+M  CW+ DP  RP+F +L
Sbjct:   10 EFPRDRIKLLDIVGTGAFGQVFLAEAVGISNKQ--VTRVACKGLKENATDSEYRDLLSELKILMHIGEHKNIVNLLGACTKGRECDL---LVIIEYCPHGNLLNFLRKRRDVFEATWSPPTEKPDETFT-----LTDLVITSFQVSRAMQFLASRRCVHRDLAARNVLVGENYVMKIADFGLARDIYKEEHYV------------KTTAGLLPVKWMAIEALVDQVYTHSSDVWSFGVLLWEIFT-------------------------------LGGSPYPGLPAN---EVYQYLMEGQRMAQPEDCPQEMYDLMLRCWQHDPAQRPTFTQL 287          

Query: 2229 LREDFSSHPNLISIIGH----CLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKT----NDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTSK 3053
            +++DF     +++ + H     LLGV  D     IV  +    ++  FLK+  L        N +++         L       A  + Y++    VH+D++ RNC +G  F + ++DF +    +   Y  I+              V LP+ WM  E I+ G +++ SD+W+FGVT+WEI T     PY  L ++          +I N  L+     S         D    +      P D   ++R     CW  +P+ RP F  +HS L N +  S+
Sbjct:   10 IKQDFFKEVKIMAGVRHENVVRLLGVCKDDPMCMIV-EYMENGDLNQFLKQRELASGNSADPNKVTYQALLYMALQL-------AAGMKYIASHQFVHRDLATRNCLVGHSFTVKIADFGMSRHLYSKHYYRIQ------------GRVILPIRWMAPECILQGKFTSASDVWAFGVTLWEILTLAAEYPYGDLTDE---------KVIENVQLMFFRPKS---------DAITFLSRPEICPPDVYAKMR----SCWAIEPSARPDFHDIHSFLENRVALSE 250          

Query: 2136 KSNIEILVARFKPNNFKIDSKSLFYRQCFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLI--------PKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLI 3041
            + NI++ +   K    + + K L       K+     SH N+++++G C     G      I+  F +  +++++LKK   I         + +D+ F      Q  L+    Q+A  + +L+    +H+D++ARN  I + + L ++DF +  + +K           N E  +H+  + +P+ W+  E++    YS KSD+WS+GV +WEIFT     PY  L                        +PS +      LD  ++       P+D +++I +IMTDCW   P  RP+F +L   L  +I
Sbjct:   50 RGNIKVAIKTLKGGATESEQKDLLSE---LKILIHVGSHKNIVNLLGAC---TKGPQRDLWIILEFCANGDLLSYLKKKRDIYDPAWCAPSEDHDVQFT-----QMELVSAAYQVARGMEFLASRRCIHRDLAARNVLIADDYVLKVADFGLARDVYK-----------NEEYVKHTPGL-VPIKWIAIESLTDKIYSQKSDVWSYGVLLWEIFT-LGGNPYPDL------------------------HPSDVF--EYLLDGKRM-----EKPVDCAQEIYNIMTDCWVLSPEDRPTFTELVKKLDKMI 304          

Query: 2055 EIDANQINLEALVTEGEIGAFVSGRLGKSNIEILVARFKPNNFKIDSKSLFYRQCFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTS 3050
            EI+  +I ++  +  G+ G    G   K N  + V   +    +++    F ++  A + +    H NL+      LLGV        I+  F    N++ +L+     PK  D+          +L+Y+  Q+  A+SYL  +  +H+D++ARNC +G++  + ++DF +     +D Y              H  A   P+ W   EA+    +S KSD+W+FG+ +WE+ T   M PY  +     DLS                         +  D     +  P  P     ++  +M  CW  DP  RPSF+++H  L  + P+S
Sbjct:    8 EIERTEIAMKHKLGGGQYGEVYEGTWKKYNKTVAVKTLREETMEVEE---FLKE--ASVMKGIK-HQNLVQ-----LLGVCTREPPFYIITEFMMNGNLLDYLRS----PKGKDLD-------AVTLMYMATQVGSAMSYLESMNFIHRDLAARNCLVGDNNLVKVADFGLSRLVSEDIY------------TAHQGA-KFPIKWTAPEALAHNTFSIKSDVWAFGILLWELAT-YGMSPYPGI-----DLS-------------------------QVYDKLDGGYRMPC-PEGCPPEVYSLMQTCWCWDPNSRPSFKEIHEKLNTMFPSS 272          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQ-GGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDED----LFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDLPKDSSSIPDLYSTVNVNIKPFDPVTTTIRPT 1322
            AWCP  PV  + +E+LQI+     F+  + TQGR +DG+  EF  SY   Y R+  + W  + D    E++  NT+      +     +VA  +R  P++    +VCLR+ LYGC + DG+  Y  P G  +      +  +D  YDG   S E  +Q GG+G+L D V+    FT+   +     +  V W R+      + + F F K R F +++++    H           VE L K    +   +  +T+  P  + +D      S+ L R  +++++ K YF   W+ I+E+ F ++   +D+ +    Y        P DP TT+  P 
Sbjct:   76 AWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDGVK-WITWKDRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYTSPVGHVMNLPGLPVYLNDSIYDG---STEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALGQGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSK--VECLFKLGILLPWSSPPLTLPVPLEDLKDPSSRPISIPLGRRPAQILLCKFYFADRWLLISEISFLSEPYEEDTDAESFSYHL------PKDPGTTSSAPV 400          

Query: 2253 PNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGE-----------HFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            PN+I ++G C+      S+   +V  +    ++  +L    L+ KT   S     +S  +L+ +  Q+A  + +LS L  VH+D++ RNC +G               + ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS L ++                 + +N         R + L +        P    + + ++M  CW  D  LRPSF  +HS L
Sbjct:  744 PNIIQLLGVCV-----SSDPLCMVTEYMECGDLNQYLSHRVLLDKTGP-SHNAPTISYPALISIASQIASGMKFLSSLNFVHRDLATRNCLVGGDRGENGEDRGGERQIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSNLTDEQ----------------VIDNAGEFFRDQGRQVYLGK--------PAVCPQGLYELMLSCWNRDCKLRPSFAHIHSFL 971          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQ-GGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDED----LFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDLPKDSSSIPDLYSTVNVNIKPFDPVTTTIRPT 1322
            AWCP  PV  + +E+LQI+     F+  + TQGR +DG+  EF  SY   Y R+  + W  + D    E++  NT+      +     +VA  +R  P++    +VCLR+ LYGC + DG+  Y  P G  +      +  +D  YDG   S E  +Q GG+G+L D V+    FT+   +     +  V W R+      + + F F K R F +++++    H           VE L K    +   +  +T+  P  + +D      S+ L R  +++++ K YF   W+ I+E+ F ++   +D+ +    Y        P DP TT+  P 
Sbjct:   76 AWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDGVK-WITWKDRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYTSPVGHVMNLPGLPVYLNDSIYDG---STEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALGQGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSK--VECLFKLGILLPWSSPPLTLPVPLEDLKDPSSRPISIPLGRRPAQILLCKFYFADRWLLISEISFLSEPYEEDTDAESFSYHL------PKDPGTTSSAPV 400          

Query: 2253 PNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGE-----------HFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            PN+I ++G C+      S+   +V  +    ++  +L    L+ KT   S     +S  +L+ +  Q+A  + +LS L  VH+D++ RNC +G               + ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS L ++                 + +N         R + L +        P    + + ++M  CW  D  LRPSF  +HS L
Sbjct:  765 PNIIQLLGVCV-----SSDPLCMVTEYMECGDLNQYLSHRVLLDKTGP-SHNAPTISYPALISIASQIASGMKFLSSLNFVHRDLATRNCLVGGDRGENGEDRGGERQIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSNLTDEQ----------------VIDNAGEFFRDQGRQVYLGK--------PAVCPQGLYELMLSCWNRDCKLRPSFAHIHSFL 992          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQ-GGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDED----LFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDLPKDSSSIPDLYSTVNVNIKPFDPVTTTIRPT 1322
            AWCP  PV  + +E+LQI+     F+  + TQGR +DG+  EF  SY   Y R+  + W  + D    E++  NT+      +     +VA  +R  P++    +VCLR+ LYGC + DG+  Y  P G  +      +  +D  YDG   S E  +Q GG+G+L D V+    FT+   +     +  V W R+      + + F F K R F +++++    H           VE L K    +   +  +T+  P  + +D      S+ L R  +++++ K YF   W+ I+E+ F ++   +D+ +    Y        P DP TT+  P 
Sbjct:   76 AWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDGVK-WITWKDRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYTSPVGHVMNLPGLPVYLNDSIYDG---STEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALGQGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSK--VECLFKLGILLPWSSPPLTLPVPLEDLKDPSSRPISIPLGRRPAQILLCKFYFADRWLLISEISFLSEPYEEDTDAESFSYHL------PKDPGTTSSAPV 400          

Query: 2253 PNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGE-----------HFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            PN+I ++G C+      S+   +V  +    ++  +L    L+ KT   S     +S  +L+ +  Q+A  + +LS L  VH+D++ RNC +G               + ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS L ++                 + +N         R + L +        P    + + ++M  CW  D  LRPSF  +HS L
Sbjct:  765 PNIIQLLGVCV-----SSDPLCMVTEYMECGDLNQYLSHRVLLDKTGP-SHNAPTISYPALISIASQIASGMKFLSSLNFVHRDLATRNCLVGGDRGENGEDRGGERQIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSNLTDEQ----------------VIDNAGEFFRDQGRQVYLGK--------PAVCPQGLYELMLSCWNRDCKLRPSFAHIHSFL 992          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQ-GGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDED----LFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDLPKDSSSIPDLYSTVNVNIKPFDPVTTTIRPT 1322
            AWCP  PV  + +E+LQI+     F+  + TQGR +DG+  EF  SY   Y R+  + W  + D    E++  NT+      +     +VA  +R  P++    +VCLR+ LYGC + DG+  Y  P G  +      +  +D  YDG   S E  +Q GG+G+L D V+    FT+   +     +  V W R+      + + F F K R F +++++    H           VE L K    +   +  +T+  P  + +D      S+ L R  +++++ K YF   W+ I+E+ F ++   +D+ +    Y        P DP TT+  P 
Sbjct:   76 AWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDGVK-WITWKDRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYTSPVGHVMNLPGLPVYLNDSIYDG---STEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALGQGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSK--VECLFKLGILLPWSSPPLTLPVPLEDLKDPSSRPISIPLGRRPAQILLCKFYFADRWLLISEISFLSEPYEEDTDAESFSYHL------PKDPGTTSSAPV 400          

Query: 2253 PNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGE-----------HFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            PN+I ++G C+      S+   +V  +    ++  +L    L+ KT   S     +S  +L+ +  Q+A  + +LS L  VH+D++ RNC +G               + ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS L ++                 + +N         R + L +        P    + + ++M  CW  D  LRPSF  +HS L
Sbjct:  725 PNIIQLLGVCV-----SSDPLCMVTEYMECGDLNQYLSHRVLLDKTGP-SHNAPTISYPALISIASQIASGMKFLSSLNFVHRDLATRNCLVGGDRGENGEDRGGERQIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSNLTDEQ----------------VIDNAGEFFRDQGRQVYLGK--------PAVCPQGLYELMLSCWNRDCKLRPSFAHIHSFL 952          

Query:  345 AWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGR-SDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQ-GGMGRLMDNVI----FTKANPINKMQSH-VVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDED----LFSLDLKRFRSKLIIIKLYFKSDWIAINEVMF 1214
            AWCP  PV  + +E+LQI+     F+  + TQGR +DG+  EF  SY   Y R+  + W  + D    E++  NT+      +     +VA  +R  P++    +VCLR+ LYGC + DG+  Y  P G  +      +  +D  YDG   S E  +Q GG+G+L D V+    FT+   +     +  V W R+      + + F F K R F +++++    H           VE L K    +   +  +T+  P  + +D      S+ L R  +++++ K YF   W+ I+E+ F
Sbjct:   66 AWCPLGPVFPSGSEYLQIDLHKLHFLALVGTQGRHADGHGQEFTRSYRLRYSRDGVK-WITWKDRWGQEVVSGNTNTHEVVLKDLGPPIVARMVRFYPLADRVMSVCLRVELYGCVWNDGLKAYTSPVGHVMNLPGLPVYLNDSIYDG---STEQRMQFGGLGQLCDGVLGGDDFTQTKELRVWPGYDYVGWSREALGQGSVDIEFHFEKPRLFINMQVHSNNRHTQGVRVFSK--VECLFKLGILLPWSSPPLTLPVPLEDLKDPSSRPISIPLGRRPAQILLCKFYFADRWLLISEISF 360          

Query: 2253 PNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGE-----------HFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLL 3029
            PN+I ++G C+      S+   +V  +    ++  +L    L+ KT   S     +S  +L+ +  Q+A  + +LS L  VH+D++ RNC +G               + ++DF +    +  DY  I+                LP+ WM WE I+MG ++T SD+W+FGVT+WE+ + CQ +PYS L ++                 + +N         R + L +        P    + + ++M  CW  D  LRPSF  +HS L
Sbjct:  519 PNIIQLLGVCV-----SSDPLCMVTEYMECGDLNQYLSHRVLLDKTGP-SHNAPTISYPALISIASQIASGMKFLSSLNFVHRDLATRNCLVGGDRGENGEDRGGERQIKIADFGMSRNLYAGDYYRIQ------------GRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLSVCQEQPYSNLTDEQ----------------VIDNAGEFFRDQGRQVYLGK--------PAVCPQGLYELMLSCWNRDCKLRPSFAHIHSFL 746          

Query:  102 MQFSSNEFDCWFLITIIFLSSQLSANTETSPRKDADGYCATGILQDSHSIRISASSVLRNDPDFGPESSRIVGLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDLPKDSSSIPDLYSTVNVNIKPFDPVTTTIRPTIYVSQNFXXXXXXXXXXXXXXXXXXVALFLCIHWMKQREKRRYKNKFFDHRSMIFNDPYTSTCGLRTISGNNPLVYRPLTPHSYVPSMPNNSQNGGFRFVHSQYPSCPDYFPNPINSEYEAIDSSWPKTVSQSMTFSDNKMENQDRQTFINNPAPDITCTNKNGVIXXXXXXXXXXXXXQPDNEINFPAPDLLPPNALTQESLNGIYKIHFNNPLKGPLGSTISNFQLAPASQTWIEKALSRIPEIDANQINLEALVTEGEIGAFVSGRLGKSNIEILVARFKPNNFKIDSKSLFYRQCFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACXXXXXXXXXXXXXXXAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTSKPLDEYGALYQLIC 3092
            MQFSSNEFDCWFLITIIFLSSQLSANTETSPRKDADGYCATGILQDSHSIRISASSVLRNDPDFGPESSRIVGLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESF+VANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDLPKDSSSIPDLYSTVNVNIKPFDPVTTTIRPTIYVSQNFIYYIILITCIIGSIILLGVALFLCIHWMKQREKRRYKNKFFDHRSMIFNDPYTSTCGLRTISGNNPLVYRPLTPHSYVPSMPNNSQNGGFRFVHSQYPSCPDYFPNPINSEYEAIDSSWPKTVSQSMTFSDNKMENQDRQTFINNPAPDITCTNKNGVIYCSASSYSSNVYSQPDNEINFPAPDLLPPNALTQESLNGIYKIHFNNPLKGPLGSTISNFQLAPASQTWIEKALSRIPEIDANQINLEALVTEGEIGAFVSGRLGKSNIEILVARFKPNNFKIDSKSLFYRQCFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACSYVSQSSLLYVVKQLAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTSKPLDEYGALYQLIC
Sbjct:    1 MQFSSNEFDCWFLITIIFLSSQLSANTETSPRKDADGYCATGILQDSHSIRISASSVLRNDPDFGPESSRIVGLVDVLTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFIVANRIRIVPISSINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFDDENYDGQKFSNETWLQGGMGRLMDNVIFTKANPINKMQSHVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLFSLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDDLPKDSSSIPDLYSTVNVNIKPFDPVTTTIRPTIYVSQNFIYYIILITCIIGSIILLGVALFLCIHWMKQREKRRYKNKFFDHRSMIFNDPYTSTCGLRTISGNNPLVYRPLTPHSYVPSMPNNSQNGGFRFVHSQYPSCPDYFPNPINSEYEAIDSSWPKTVSQSMTFSDNKMENQDRQTFINNPAPDITCTNKNGVIYCSASSYSSNVYSQPDNEINFPAPDLLPPNALTQESLNGIYKIHFNNPLKGPLGSTISNFQLAPASQTWIEKALSRIPEIDANQINLEALVTEGEIGAFVSGRLGKSNIEILVARFKPNNFKIDSKSLFYRQCFAKLREDFSSHPNLISIIGHCLLGVVGDSNTSSIVYAFPSQVNVVTFLKKLHLIPKTNDISFACSYVSQSSLLYVVKQLAGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFNNEGNQHSAAVHLPLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALCNQAQDLSLIIPNIIRNSMLIANNNPSSILPNNRTLDLTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTSKPLDEYGALYQLIC 997          

Query:  261 ASSVLRNDPDFGPESSRIVGLVDV-LTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPIS-SINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFD--DENYDG----QKFSNETWLQGGMGRLMDNVIFTKA---NPINKMQS-HVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLF-----SLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDD----LPKDSSSI----PDLYSTVNVNIKPFDPVTTTIRP 1319
            ASSV +   +F P  +R+  + D  L   AWCP + + ++P EW++I+    K I  + T GR DGN+ E+ P +Y DYQR S + W RY + +  +L+  NTD RN A   FES ++A RIRI PIS       C+RI +YGCDF DGV EY + +G      N +  +D  D  YDG     K + +  L+ G+G+LMDNVI+      +  NK++  H V W RK    + + ++ KF ++R  + ++ Y             S  + F   +  G+     S      T  D  ++     ++ L+   ++ + I L+F+ DWI ++E++  ++     +PK+S SI    P  ++  +V   P D   T + P
Sbjct:   59 ASSVWKEIVEFEPHQARMKQMDDPNLLGHAWCPKQMIKSSPEEWIEIDLGDLKMIKNLATAGRGDGNFAEYAPHFYLDYQRVSGK-WIRYRNQRKEQLLNGNTDARNVAMTNFESMIIARRIRIYPISKEKQIRACMRIIIYGCDFDDGVVEYSVSQGHYYTARNGNEKYDLRDLTYDGVISIDKSNPKGLLEEGLGQLMDNVIYNGVISEDHNNKIRGYHFVGWNRKFLDSNKVEIVMKFDQMRSVKQIRFYAMNMIPEDIGVFSSAIIHF---SRGGVYYDRISPAYQFKTVIDTRVYYPRWINITLQNVLARFLKIDLFFEVDWIILSEIVIISEKYNEIIPKESESIQTNYPITHNITSVKYIPTDSTATVLIP 432          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFN-NEGNQHSAAVHL-----PLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALC-------NQAQDLSLIIPN-IIRNSMLIANNNPSSILPNNRTLD-LTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTSKPLDEYGALYQLI 3089
            A  +SYL    I+H+D++ARNC IG++  + ++D A+ +++FK+ YI   +     NE    ++++ +     PL WM +E+I+   YS K+DIWSFGVTMWEI   CQ  PY           + A +LS+   + +  N  L  + + S+  P+    +  + I+HE+    L  S+   D++ +CW  +P  RP+F+ + S+L   I   +  +++  L+  I
Sbjct:  951 ARGMSYLESRQIIHRDLAARNCLIGQNLKIKITDIAMSIQKFKEHYIECAVVGIQKNEDCDSNSSISVVKRFYPLQWMAFESILQATYSCKTDIWSFGVTMWEILHRCQQTPYGGFAISFDRIRDNAYNLSIGNSSAVFPNENLYPHQSQSNFRPSQHMANPSSSILHED----LGLSRDFSDLIQECWNRNPHQRPTFKLISSILEQKITNFEFANDHSNLFSTI 1172          

Query:  261 ASSVLRNDPDFGPESSRIVGLVDV-LTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPIS-SINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFD--DENYDG----QKFSNETWLQGGMGRLMDNVIFTKA---NPINKMQS-HVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLF-----SLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDD----LPKDSSSI----PDLYSTVNVNIKPFDPVTTTIRP 1319
            ASSV +   +F P  +R+  + D  L   AWCP + + ++P EW++I+    K I  + T GR DGN+ E+ P +Y DYQR S + W RY + +  +L+  NTD RN A   FES ++A RIRI PIS       C+RI +YGCDF DGV EY + +G      N +  +D  D  YDG     K + +  L+ G+G+LMDNVI+      +  NK++  H V W RK    + + ++ KF ++R  + ++ Y             S  + F   +  G+     S      T  D  ++     ++ L+   ++ + I L+F+ DWI ++E++  ++     +PK+S SI    P  ++  +V   P D   T + P
Sbjct:   76 ASSVWKEIVEFEPHQARMKQMDDPNLLGHAWCPKQMIKSSPEEWIEIDLGDLKMIKNLATAGRGDGNFAEYAPHFYLDYQRVSGK-WIRYRNQRKEQLLNGNTDARNVAMTNFESMIIARRIRIYPISKEKQIRACMRIIIYGCDFDDGVVEYSVSQGHYYTARNGNEKYDLRDLTYDGVISIDKSNPKGLLEEGLGQLMDNVIYNGVISEDHNNKIRGYHFVGWNRKFLDSNKVEIVMKFDQMRSVKQIRFYAMNMIPEDIGVFSSAIIHF---SRGGVYYDRISPAYQFKTVIDTRVYYPRWINITLQNVLARFLKIDLFFEVDWIILSEIVIISEKYNEIIPKESESIQTNYPITHNITSVKYIPTDSTATVLIP 449          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFN-NEGNQHSAAVHL-----PLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALC-------NQAQDLSLIIPN-IIRNSMLIANNNPSSILPNNRTLD-LTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTSKPLDEYGALYQLI 3089
            A  +SYL    I+H+D++ARNC IG++  + ++D A+ +++FK+ YI   +     NE    ++++ +     PL WM +E+I+   YS K+DIWSFGVTMWEI   CQ  PY           + A +LS+   + +  N  L  + + S+  P+    +  + I+HE+    L  S+   D++ +CW  +P  RP+F+ + S+L   I   +  +++  L+  I
Sbjct:  968 ARGMSYLESRQIIHRDLAARNCLIGQNLKIKITDIAMSIQKFKEHYIECAVVGIQKNEDCDSNSSISVVKRFYPLQWMAFESILQATYSCKTDIWSFGVTMWEILHRCQQTPYGGFAISFDRIRDNAYNLSIGNSSAVFPNENLYPHQSQSNFRPSQHMANPSSSILHED----LGLSRDFSDLIQECWNRNPHQRPTFKLISSILEQKITNFEFANDHSNLFSTI 1189          

Query:  261 ASSVLRNDPDFGPESSRIVGLVDV-LTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPIS-SINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFD--DENYDG----QKFSNETWLQGGMGRLMDNVIFTKA---NPINKMQS-HVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLF-----SLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDD----LPKDSSSI----PDLYSTVNVNIKPFDPVTTTIRP 1319
            ASSV +   +F P  +R+  + D  L   AWCP + + ++P EW++I+    K I  + T GR DGN+ E+ P +Y DYQR S + W RY + +  +L+  NTD RN A   FES ++A RIRI PIS       C+RI +YGCDF DGV EY + +G      N +  +D  D  YDG     K + +  L+ G+G+LMDNVI+      +  NK++  H V W RK    + + ++ KF ++R  + ++ Y             S  + F   +  G+     S      T  D  ++     ++ L+   ++ + I L+F+ DWI ++E++  ++     +PK+S SI    P  ++  +V   P D   T + P
Sbjct:   61 ASSVWKEIVEFEPHQARMKQMDDPNLLGHAWCPKQMIKSSPEEWIEIDLGDLKMIKNLATAGRGDGNFAEYAPHFYLDYQRVSGK-WIRYRNQRKEQLLNGNTDARNVAMTNFESMIIARRIRIYPISKEKQIRACMRIIIYGCDFDDGVVEYSVSQGHYYTARNGNEKYDLRDLTYDGVISIDKSNPKGLLEEGLGQLMDNVIYNGVISEDHNNKIRGYHFVGWNRKFLDSNKVEIVMKFDQMRSVKQIRFYAMNMIPEDIGVFSSAIIHF---SRGGVYYDRISPAYQFKTVIDTRVYYPRWINITLQNVLARFLKIDLFFEVDWIILSEIVIISEKYNEIIPKESESIQTNYPITHNITSVKYIPTDSTATVLIP 434          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFN-NEGNQHSAAVHL-----PLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALC-------NQAQDLSLIIPN-IIRNSMLIANNNPSSILPNNRTLD-LTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTSKPLDEYGALYQLI 3089
            A  +SYL    I+H+D++ARNC IG++  + ++D A+ +++FK+ YI   +     NE    ++++ +     PL WM +E+I+   YS K+DIWSFGVTMWEI   CQ  PY           + A +LS+   + +  N  L  + + S+  P+    +  + I+HE+    L  S+   D++ +CW  +P  RP+F+ + S+L   I   +  +++  L+  I
Sbjct:  953 ARGMSYLESRQIIHRDLAARNCLIGQNLKIKITDIAMSIQKFKEHYIECAVVGIQKNEDCDSNSSISVVKRFYPLQWMAFESILQATYSCKTDIWSFGVTMWEILHRCQQTPYGGFAISFDRIRDNAYNLSIGNSSAVFPNENLYPHQSQSNFRPSQHMANPSSSILHED----LGLSRDFSDLIQECWNRNPHQRPTFKLISSILEQKITNFEFANDHSNLFSTI 1174          

Query:  261 ASSVLRNDPDFGPESSRIVGLVDV-LTPKAWCPDKPVHNTPTEWLQIEFSSTKFITCIFTQGRSDGNYGEFVPSYYFDYQRESSQTWYRYNDTKNGELIPANTDYRNAAYQKFESFLVANRIRIVPIS-SINTNVCLRIRLYGCDFKDGVFEYQIPRGDSIFRDNTSILFD--DENYDG----QKFSNETWLQGGMGRLMDNVIFTKA---NPINKMQS-HVVAWKRKTDLMDHIVLLFKFRKVRQFQSLKIYFTKYHLYRFDTAKSLTVEFLEKNEKGISQITNSITVSNPTFNDEDLF-----SLDLKRFRSKLIIIKLYFKSDWIAINEVMFETDD----LPKDSSSI----PDLYSTVNVNIKPFDPVTTTIRP 1319
            ASSV +   +F P  +R+  + D  L   AWCP + + ++P EW++I+    K I  + T GR DGN+ E+ P +Y DYQR S + W RY + +  +L+  NTD RN A   FES ++A RIRI PIS       C+RI +YGCDF DGV EY + +G      N +  +D  D  YDG     K + +  L+ G+G+LMDNVI+      +  NK++  H V W RK    + + ++ KF ++R  + ++ Y             S  + F   +  G+     S      T  D  ++     ++ L+   ++ + I L+F+ DWI ++E++  ++     +PK+S SI    P  ++  +V   P D   T + P
Sbjct:   59 ASSVWKEIVEFEPHQARMKQMDDPNLLGHAWCPKQMIKSSPEEWIEIDLGDLKMIKNLATAGRGDGNFAEYAPHFYLDYQRVSGK-WIRYRNQRKEQLLNGNTDARNVAMTNFESMIIARRIRIYPISKEKQIRACMRIIIYGCDFDDGVVEYSVSQGHYYTARNGNEKYDLRDLTYDGVISIDKSNPKGLLEEGLGQLMDNVIYNGVISEDHNNKIRGYHFVGWNRKFLDSNKVEIVMKFDQMRSVKQIRFYAMNMIPEDIGVFSSAIIHF---SRGGVYYDRISPAYQFKTVIDTRVYYPRWINITLQNVLARFLKIDLFFEVDWIILSEIVIISEKYNEIIPKESESIQTNYPITHNITSVKYIPTDSTATVLIP 432          

Query: 2457 AGALSYLSELGIVHKDVSARNCSIGEHFHLILSDFAIGMEEFKDDYIPIRLFPFN-NEGNQHSAAVHL-----PLFWMPWEAIIMGNYSTKSDIWSFGVTMWEIFTECQMKPYSALC-------NQAQDLSLIIPN-IIRNSMLIANNNPSSILPNNRTLD-LTQIVHENPTNPLDSSKQIRDIMTDCWKSDPTLRPSFQKLHSLLCNLIPTSKPLDEYGALYQLI 3089
            A  +SYL    I+H+D++ARNC IG++  + ++D A+ +++FK+ YI   +     NE    ++++ +     PL WM +E+I+   YS K+DIWSFGVTMWEI   CQ  PY           + A +LS+   + +  N  L  + + S+  P+    +  + I+HE+    L  S+   D++ +CW  +P  RP+F+ + S+L   I   +  +++  L+  I
Sbjct:  951 ARGMSYLESRQIIHRDLAARNCLIGQNLKIKITDIAMSIQKFKEHYIECAVVGIQKNEDCDSNSSISVVKRFYPLQWMAFESILQATYSCKTDIWSFGVTMWEILHRCQQTPYGGFAISFDRIRDNAYNLSIGNSSAVFPNENLYPHQSQSNFRPSQHMANPSSSILHED----LGLSRDFSDLIQECWNRNPHQRPTFKLISSILEQKITNFEFANDHSNLFSTI 1172