slc22a-5
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppSub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024134 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of slc22a-5 vs. Ensembl Human
Match: SLC22A5 (solute carrier family 22 member 5 [Source:HGNC Symbol;Acc:HGNC:10969]) HSP 1 Score: 166.007 bits (419), Expect = 6.005e-44 Identity = 123/415 (29.64%), Postives = 210/415 (50.60%), Query Frame = 2
Query: 356 NWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-----SLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
W++++ +TI TE+NLVC L ++FFVG+ +G+FI+ D+ GR ++ + + + + F+ N + ++L L G+G Y L TEI+ R +++ I Y GYM++P AY +DWR L L +L ++ +PESPRWL G+F++A + AK NG + P FD L KQ+ NI D+ + +R+ + I + TISV YFGLS++ L +IF+N F+ ++E +AW++ L RR SM + L+ F + + + L +GKF +T A+ + +Y E++PT +RNM + + + + ++ +P + D F+PY +++ I + FLPE+ G PLP T+++
Sbjct: 116 GWEFSQDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLL---FMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAI----LTLFLPESFGTPLPDTIDQ 523
BLAST of slc22a-5 vs. Ensembl Human
Match: SLC22A5 (solute carrier family 22 member 5 [Source:HGNC Symbol;Acc:HGNC:10969]) HSP 1 Score: 156.377 bits (394), Expect = 2.148e-40 Identity = 118/403 (29.28%), Postives = 202/403 (50.12%), Query Frame = 2
Query: 392 ISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-----SLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
+ ++NLVC L ++FFVG+ +G+FI+ D+ GR ++ + + + + F+ N + ++L L G+G Y L TEI+ R +++ I Y GYM++P AY +DWR L L +L ++ +PESPRWL G+F++A + AK NG + P FD L KQ+ NI D+ + +R+ + I + TISV YFGLS++ L +IF+N F+ ++E +AW++ L RR SM + L+ F + + + L +GKF +T A+ + +Y E++PT +RNM + + + + ++ +P + D F+PY +++ I + FLPE+ G PLP T+++
Sbjct: 152 LPAQWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLL---FMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAI----LTLFLPESFGTPLPDTIDQ 547
BLAST of slc22a-5 vs. Ensembl Human
Match: SLC22A4 (solute carrier family 22 member 4 [Source:HGNC Symbol;Acc:HGNC:10968]) HSP 1 Score: 134.806 bits (338), Expect = 4.350e-33 Identity = 132/534 (24.72%), Postives = 243/534 (45.51%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWT-------VKECQAIARS-----------------ENGTNHTI------YCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDS---LIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNN---FYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELR 1579
+Y+E I+ + F L LS + + S+VF+ TP ++C P W +++ + + S E G + + C + W++++ +T+ TE+NLVC V L ++FFVG+ +G+F++ D+ GR ++ + + + F+ + + +L + G+G Y L TEI+ R +++ + +GYML+P AY +DWR L L +L ++ +PESPRWL +F++A + AK N P FDS L KQ+ I D+F ++ + + + + + SV YF LS++ L + +LN F+ L+E AW++ L RR ++I +V F + + L +GKF +T+A+ + ++ E++PT +RNM++ + + + ++ AP + + +PY +V+ G+L FF PE+ G LP+TLE+ +++
Sbjct: 3 DYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSSAWRNNSVPLRLRDGREVPHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRR------YIIAAVLFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLI---GILTLFF-PESLGMTLPETLEQMQKVK 526
BLAST of slc22a-5 vs. Ensembl Human
Match: SLC22A3 (solute carrier family 22 member 3 [Source:HGNC Symbol;Acc:HGNC:10967]) HSP 1 Score: 131.724 bits (330), Expect = 4.385e-32 Identity = 116/435 (26.67%), Postives = 218/435 (50.11%), Query Frame = 2
Query: 305 QAIARSENGTNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNF-IAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL--TEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNIT--DIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP----SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNEL 1576
+A N + + CR W+Y + +TI +EF+LVC + L + +G G F + D+ GR+ + L+ + + + + FA N + ++ RFL G+ GK CY+ TEIV K+R + + + LG +++PG+AY +W+ + + LF L Y+++PESPRWL K KA+ L IAK NGK N + + +T +++ N + D+ + MR +L+F T +V Y GL + + N++++ FI G++E + + +L RR+ + ++ V ++ +F ++ + +T+ ++G+ +T A+ I + +E++PT +RN + + G+ + AP + + +P + ++ I G L+ LPETKG LP+T+++ +L
Sbjct: 112 DPLAAFPNRSAPLVPCRGGWRYAQAH--STIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGV-FGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSN-YSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVT---AFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLI---IFGILASICGGLV-MLLPETKGIALPETVDDVEKL 535
BLAST of slc22a-5 vs. Ensembl Human
Match: SLC22A24 (solute carrier family 22 member 24 [Source:HGNC Symbol;Acc:HGNC:28542]) HSP 1 Score: 126.716 bits (317), Expect = 2.647e-30 Identity = 113/425 (26.59%), Postives = 206/425 (48.47%), Query Frame = 2
Query: 359 WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLT-EIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIIT---KQKLG------NITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGP-VAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNEN 1594
W Y+++ +TI TE++LVC + +++ ++F G +G I D++GR + L + I N C FA + +LRFL+G T I L+ E + RS+ Y +G ML+ GLA+ +DW L + ++ +L+ + + ES RWL I + + + L +A NGK E + ++ K++L +I +F + +R+++F L FV I+V ++GL +N L SN+ L + G + TFT V+ + + + RR+S ++ + +++N F I+ +V++TLG IG + + ++ NE+ PT +R+ I AP + + + P+ Y V +++ + + LPET+ PLP T+++ RK + N
Sbjct: 120 WVYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCFLQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTIMVLLCSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQLDEGLKELRRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVFGLCFVRFAITVPFYGLILNLQHLGSNVSLFQILCGAV-TFTARCVSLLTLNHMGRRISQILFTFPVGLFILVNTFLPQEMQILRVVLATLG-IGSVSAASNSAS--VHHNELVPTILRSTVAGINAVSGRTGAALAPLLMTLMAYSPHLPWISYGVFPILA-VPVILLLPETRDLPLPNTIQDVENDRKDSRN 539
BLAST of slc22a-5 vs. Ensembl Celegans
Match: oct-1 (Organic cation transporter 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U539]) HSP 1 Score: 130.954 bits (328), Expect = 3.336e-32 Identity = 117/462 (25.32%), Postives = 213/462 (46.10%), Query Frame = 2
Query: 266 FNQTQLTWTVKECQAIARSENGTNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGN-FIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQ-GLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXX-XXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGK--IFPENKFDSLIITK--------QKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSV----CLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENN 1597
+N+TQ+ A + + + C+N W Y+ + +++ TEFNLVC+++ ++ + T F+VG +GN DK GR R + + I+ FA +I I+LRF +GL ++Q E + R + + L+ +A + WR N P + + YF LPESPRW GK+ A L IAK NGK + + DS+ + ++ N+TD+F + +R K ++ ++ ++ Y GL++N S L + + + I G +E V W + RR ++ ++C + + + + Y + ++++ IGKF + + + + ++ E++PT +R + + + +A + AP I + + + +M L +G+L FFLPET G PLP T+E+ K E +
Sbjct: 80 YNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNGKSNVDVDELVDSMKNHQNAAEEKETKRSHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCVSAMFMPDGYPW-------LVASASFIGKFGVGSGFAVIYIFAGELYPTVVRAIGMGMSSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILT-FFLPETLGAPLPMTIEDAENFGKKPEPD 533
BLAST of slc22a-5 vs. Ensembl Celegans
Match: oct-1 (Organic cation transporter 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U539]) HSP 1 Score: 130.954 bits (328), Expect = 3.336e-32 Identity = 117/462 (25.32%), Postives = 213/462 (46.10%), Query Frame = 2
Query: 266 FNQTQLTWTVKECQAIARSENGTNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGN-FIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQ-GLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXX-XXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGK--IFPENKFDSLIITK--------QKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSV----CLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENN 1597
+N+TQ+ A + + + C+N W Y+ + +++ TEFNLVC+++ ++ + T F+VG +GN DK GR R + + I+ FA +I I+LRF +GL ++Q E + R + + L+ +A + WR N P + + YF LPESPRW GK+ A L IAK NGK + + DS+ + ++ N+TD+F + +R K ++ ++ ++ Y GL++N S L + + + I G +E V W + RR ++ ++C + + + + Y + ++++ IGKF + + + + ++ E++PT +R + + + +A + AP I + + + +M L +G+L FFLPET G PLP T+E+ K E +
Sbjct: 80 YNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNGKSNVDVDELVDSMKNHQNAAEEKETKRSHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCVSAMFMPDGYPW-------LVASASFIGKFGVGSGFAVIYIFAGELYPTVVRAIGMGMSSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILT-FFLPETLGAPLPMTIEDAENFGKKPEPD 533
BLAST of slc22a-5 vs. Ensembl Celegans
Match: oct-1 (Organic cation transporter 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U539]) HSP 1 Score: 130.954 bits (328), Expect = 4.166e-32 Identity = 117/462 (25.32%), Postives = 213/462 (46.10%), Query Frame = 2
Query: 266 FNQTQLTWTVKECQAIARSENGTNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGN-FIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQ-GLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXX-XXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGK--IFPENKFDSLIITK--------QKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSV----CLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENN 1597
+N+TQ+ A + + + C+N W Y+ + +++ TEFNLVC+++ ++ + T F+VG +GN DK GR R + + I+ FA +I I+LRF +GL ++Q E + R + + L+ +A + WR N P + + YF LPESPRW GK+ A L IAK NGK + + DS+ + ++ N+TD+F + +R K ++ ++ ++ Y GL++N S L + + + I G +E V W + RR ++ ++C + + + + Y + ++++ IGKF + + + + ++ E++PT +R + + + +A + AP I + + + +M L +G+L FFLPET G PLP T+E+ K E +
Sbjct: 97 YNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNGKSNVDVDELVDSMKNHQNAAEEKETKRSHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCVSAMFMPDGYPW-------LVASASFIGKFGVGSGFAVIYIFAGELYPTVVRAIGMGMSSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILT-FFLPETLGAPLPMTIEDAENFGKKPEPD 550
BLAST of slc22a-5 vs. Ensembl Celegans
Match: Y82E9BR.16 (pep chromosome:WBcel235:III:1419867:1427226:-1 gene:WBGene00022348.1 transcript:Y82E9BR.16a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y82E9BR.16) HSP 1 Score: 111.694 bits (278), Expect = 8.909e-26 Identity = 111/468 (23.72%), Postives = 201/468 (42.95%), Query Frame = 2
Query: 350 CRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNF-IAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLT-----EIVSIKRRSL---------------------YTNNYWILYVLGYMLIPGL---------AYGTKDWRLSRHLMNXXXXXXXXXXX--XXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSL-----------IITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSING--IDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQT---LEEGNELRKGNE 1591
C ++ + + T + + C++ + ++VG G+ + GD+IGR ++ LA++ +I + A WL L R GTG + G+ + E+V K R L Y NY IL+V+ + P L A K + L +F L + +PES RWL ++K+A L A NG + PEN ++ L +KL D+F + +R + V+ F+ IS+ Y+G+++ + L +I++N +E + +++ ++ RR+ + I CL++N + + + + T + K ++T Y Y E+FPT IRN ++ IA + + A I+ ++F F + M +++ ++ FLPET G PLP++ +EEG+ R +E
Sbjct: 105 CHEHIFDHSKVEYTAVQRWEITCDRSWIKATIQAAYYVGQMAGSTTFGMLGDRIGRKKVFFLAIVIQITCAYLIAIAPYWWLYALAR----AGTGFSHPGIFVIAVVIGMELVGPKYRKLASVITGLFFALGQIFLGIEAIYFTNYQILHVV--IASPALLFLSYCQKSAKNRKKIDFANFLADFLLKNRFFFSRWLVPESARWLVSQKRYKEADEVLQKAASVNGTVLPENWWEQLDDSTTGGGGAPGAPTKKLTG-ADLFRTPELRKRTLVVFFLWPVISMVYYGMAMKANVLGGDIYVNFIFAAFVEIPALFIVYLLIDRIGRRLILAGGLFIAGACLLVN--WLMGDNVQLWMAITQMAFTKGSITGVYAAIYTYSPELFPTVIRNTAMGFCSTIARVGAIAASYISMWIAEQFGKVFMIIPFGCMAVLAAVMTLLFLPETMGKPLPESIEEIEEGDSYRSSHE 563
BLAST of slc22a-5 vs. Ensembl Celegans
Match: K05F1.6 (pep chromosome:WBcel235:II:5782942:5787658:1 gene:WBGene00019408.1 transcript:K05F1.6c.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05F1.6) HSP 1 Score: 92.4337 bits (228), Expect = 2.243e-19 Identity = 112/461 (24.30%), Postives = 195/461 (42.30%), Query Frame = 2
Query: 350 CRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGL-GTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSR------HLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNIT------------------------DIFGSKIMRLKMFVLIFVHGTISVSYFGLSI---NESFLSSNIF-----LNVFIQGLLETFT-GPVAWIMSSKLNRRVSMLIN------FLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFI--------PYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEG 1567
C+ + + K M TI T+FNLVC+ + + +G +G + I DKIGR I I ++ + LPF + +L+R LS + EI K R++ + + LGY L+ +AY TK W+ + H M+ + +PESPRWL + + +A ++ FP N + T K GN+ D+F K +R + + V ++ Y+GL + ++S +F LN I G +E T W+M +L R+ ++++ F+I ++ M++ Y + GK A+ A+ I ++ +E++PT +RN ++ G+ S+ F +G+ +I P ++V L +G+L+ F LPET PLP+TL++
Sbjct: 330 CQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLGCVLGGIASDKIGRKPTIIGFGILSSMLGVFLPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMS-----IIFICSIPESPRWLMVQNRVSEA--EEVIRKACREPPFPFN-----MCTTSKCGNLPSDLELVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMM--QLGRKKALMLTLITSGLFIIVAMLSMVSGHYMLALAFMY--------FGKIAVQGAFNILYIFTSELYPTVVRNTAV----GVTSMVARFG---SGLSSYIALLSNISLPIVPMIIFAVFSLFAGMLV-FVLPETSEKPLPETLDDA 760
BLAST of slc22a-5 vs. Ensembl Fly
Match: Balat (gene:FBgn0033778 transcript:FBtr0087815) HSP 1 Score: 135.961 bits (341), Expect = 1.450e-33 Identity = 124/443 (27.99%), Postives = 208/443 (46.95%), Query Frame = 2
Query: 296 KECQAIARSENGTNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLT-EIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNG----KIFPENKFDSLIITKQKLGN--------ITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNEL 1576
++ + + + + T + C++ W Y+K+ ++T+ E+NLVC++ VTL +F VG +GN++ D GR + ++ EII FA N + + LRF+ GL I L E+V +RR T I Y LG +++ G+ Y +DWR LS + L+ + +F+LPESPRWL GK ++AI L ++A+ NG + F E L+IT+ I D+F MR K ++ + + Y GLS L + N F+ G +E T + W S RR + I+ L+ V + Y + L +GK +++++ + + +E++PT +R + + I+ + + P IN + + + + LI G LPET+ LPQTLEEG +
Sbjct: 107 QQAEDLLKLQPDTTQVVPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFLYP-------DITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVLPLIVMGAL-LILGGFASLLLPETRNRNLPQTLEEGEAV 541
BLAST of slc22a-5 vs. Ensembl Fly
Match: CG6126 (gene:FBgn0038407 transcript:FBtr0083278) HSP 1 Score: 130.954 bits (328), Expect = 4.546e-32 Identity = 117/520 (22.50%), Postives = 231/520 (44.42%), Query Frame = 2
Query: 116 EEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWT------------------VKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNF-IAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGL--GTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXX-XXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLG-------NITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGN 1588
E+ + ++ ++ L + + M + S+V + P ++C + + L+ T ++ C S GTN TI C + Y+ T + + ++N VC+++ ++ T+F +G+ G + DK+GR + + ++++II + + F + ++ R+L G+ G G E+V +R++ + ++ G ML+ G D + + + LF ++ L ESPRWL + G+ +A+ + + NG P +K + KQ+ ++D+F + +R+K + S+ Y+GLS++ L N +L +FI GL+E + + +L RR L +C ++ + + + + V+ GK + ++ + Y E+FPT +RN ++ + A + P I +D F P + V+ LISG + FLPET P+P+++E+G KG+
Sbjct: 8 EDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSAILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDRQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGSTTSTAVVMA----GKLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWV-MFLPETMNQPMPESIEDGENFGKGD 522
BLAST of slc22a-5 vs. Ensembl Fly
Match: CG7458 (gene:FBgn0037144 transcript:FBtr0078475) HSP 1 Score: 123.25 bits (308), Expect = 1.668e-29 Identity = 114/431 (26.45%), Postives = 199/431 (46.17%), Query Frame = 2
Query: 353 RNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTM----FFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLS-GLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIIT-KQKLGNITDIFGSKIMRLKMFVLI---------FVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENN 1597
R++K+ D TISTEF + C + ++++ T+ FVG+ +G + A D+ GR ++ +A ++ + ++N + ++ FL +G+ E+V KRR I Y LG + LA + WR L R L +L L ++LPES RWL G +KA L A+ N + PE + + L+ + +QKL + IMR +F + F H I++ GLS+N L N + N + G ++ + ++ ++ RR S+ + L+C++C+ + + L IGK A+T ++ I + +E+FPT +RN + + + I ++ AP + ++ Y ++ LISG L F PET LP T+EE +L + +
Sbjct: 151 RDFKFR--DEEKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFA---DRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLTSNRQKLSQANES-QYPIMRAVVFFSLRIANCCLCWFTHTLIAL---GLSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGAS---AAVPADNYAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAF-PETADKVLPTTIEEARDLNQAKRRS 568
BLAST of slc22a-5 vs. Ensembl Fly
Match: CG8654 (gene:FBgn0034479 transcript:FBtr0086340) HSP 1 Score: 122.094 bits (305), Expect = 2.359e-29 Identity = 112/438 (25.57%), Postives = 208/438 (47.49%), Query Frame = 2
Query: 317 RSENGTNH-TIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGT-GKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXX-XXXESPRWLGIGGKFKKAITNLLLIAKYNGK----IFPE--NKFDSLIITKQ-KLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENN 1597
++EN T+ + C +++ + +TI TE+NL C K+ +L ++ +G+ G+ + + D+ GR ++I + + + W L RFL + T G + L EIV K+R + Y I + +G+ + AY ++WR + + + ++ Y L+PESPRWL GK K+I L IAK N I PE + +L + K G + D+F + MR+K + + + Y+G + S L NIF++ I + + +M+ L R+ ++L++ ++ L+L S V T +IG F + + +Y E+FPT +R+ + + + I ++ AP I + + + + + + +++ +L FLPET+G PLP+TLE+G + ++
Sbjct: 68 KTENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPEIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYLGRKKTLLLSNGCSALGLILLACLS---TQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILA-MLGTIFLPETRGTPLPETLEDGETFGRKKKDQ 501
BLAST of slc22a-5 vs. Ensembl Fly
Match: CG8654 (gene:FBgn0034479 transcript:FBtr0305676) HSP 1 Score: 122.094 bits (305), Expect = 2.359e-29 Identity = 112/438 (25.57%), Postives = 208/438 (47.49%), Query Frame = 2
Query: 317 RSENGTNH-TIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGT-GKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXX-XXXESPRWLGIGGKFKKAITNLLLIAKYNGK----IFPE--NKFDSLIITKQ-KLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENN 1597
++EN T+ + C +++ + +TI TE+NL C K+ +L ++ +G+ G+ + + D+ GR ++I + + + W L RFL + T G + L EIV K+R + Y I + +G+ + AY ++WR + + + ++ Y L+PESPRWL GK K+I L IAK N I PE + +L + K G + D+F + MR+K + + + Y+G + S L NIF++ I + + +M+ L R+ ++L++ ++ L+L S V T +IG F + + +Y E+FPT +R+ + + + I ++ AP I + + + + + + +++ +L FLPET+G PLP+TLE+G + ++
Sbjct: 68 KTENVTDPCSDECSETEFDTSVFQSTIITEWNLTCESKQLASLSQSIVMLGILFGSILFGMFADRYGRRPAFLTCCFMQLITGLIVCVSPYYWFYCLFRFLVAVATAGTMTTSFVLLMEIVGPKKREMVAILYQIPFNIGHASLALFAYFIREWRWFQFSITIFSIVFVIYIWLVPESPRWLFTTGKLDKSIKILEKIAKCNKAPTETIRPEIEAAYGALAARQPVKKGTVVDLFRTPYMRIKTIFMANNWLVVCMVYYGTAQYVSALGGNIFISNAIAAGVGIPGTCLCALMTKYLGRKKTLLLSNGCSALGLILLACLS---TQAEAVRVTCATIGLFGASITFPNVYLYGGELFPTVVRSSGVGLCSMVGRIGSIVAPLIVDLAAYGLWVAPLIFGIFSILA-MLGTIFLPETRGTPLPETLEDGETFGRKKKDQ 501
BLAST of slc22a-5 vs. Ensembl Zebrafish
Match: slc22a13a (solute carrier family 22 member 13a [Source:ZFIN;Acc:ZDB-GENE-070912-473]) HSP 1 Score: 137.887 bits (346), Expect = 2.171e-34 Identity = 133/529 (25.14%), Postives = 232/529 (43.86%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKC-------VDP-IFNQTQLTWTVKE--------CQAI--------ARSENGTNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIY-QGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLM-NXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQ-KLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLN---RRVSMLIN------FLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRK 1582
N+ E + I F L L L I ++S+VF ++ C DP + + QL T+ CQ A E G N T C + W +N T TI T+F+LVC T+FF G+ VG + + GR R + ++ +I + + N ++ ++ +F++G+G G + +E + + +RS +L LG ++ + Y +DWRL + +M + + + LPES RWL G+ K A + A N + PE+ + ++ K + G I +FGS+++R + F ++++Y+ LS+N +IFL I GL E PV ++ L R+ S++++ + +V + N+ + + L + G+F + A +C++Y E+FPT IR + + A ++ +P +N ++ F S + L SG + F LPET+ LP + EE RK
Sbjct: 3 NFGEILEAIGDFGLFQKLLLFALCFPNLILPFQLSSLVFNHADTNHHCNTDWILKADPNLTKEEQLNLTLPRLSDGSFNPCQMYKPVDWNLSAIQEYGLNQTTTCTDGWVHNDTIYEATIVTDFDLVCENVNIFRGAQTVFFAGVLVGAILFGPFSESFGRKRATQIPMVLMLIFTVVTGLSPNFYVYLVSQFINGVGLGGFRINSIILASEWIGVAQRSYAACLSQVLAALGQVMFLAVVYFVRDWRLDQFIMAGPIGIVVIYIWFLPESARWLLDRGRTKDAKKLIQKAAAVNKRAVPESLVEEVLKEKPVEKGGIKILFGSRVLRKYFLAITFAWCALNLAYYSLSLNVGKFGLDIFLTQLIFGLSEI---PVHFLCMWSLEVVGRKPSLIVSLVLGGCLCLLTVAVPQNSSIAI---------AVLATCGRFLMNAAGSVCNVYFQELFPTSIRQTATGLGSTAARAGSMLSPVVNMLEIFHFSIPMVVISSLALASG-VTAFLLPETRRTELPASTEEAEGKRK 518
BLAST of slc22a-5 vs. Ensembl Zebrafish
Match: slc22a7b.1 (solute carrier family 22 member 7b, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1311]) HSP 1 Score: 135.191 bits (339), Expect = 1.985e-33 Identity = 141/537 (26.26%), Postives = 244/537 (45.44%), Query Frame = 2
Query: 107 MNYEEAISEIQG--NERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKC------VDPIFNQTQLTWTVKECQAIARSENGTNHT-----------------------IYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICG---DKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLG-TGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGK------IFPENKFDSLIITK--QKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRK 1582
M +E ++E+ G +F ++ALL + + +N+ FI PS+ C D IF LT + + E+GT + + C+N W+++ + +T++TEF+LVC+++ T+FF G+ +G AI G D+ GR R++ LA + I + FA + + ++RF +G+G TG + E I R++ + + L M++ G+AY DWR L + L +T+ LPES RWL GK ++A L A N + I PE + +I + + + + SK+ +L M I G ++ +Y+G+S N S N++L FI G +E + VA++ KL RR S + + VC+ + + VI+ LG F+ + C+ +Y E++PT +R + I + AP ++ +DE + + +++GLL LPET LP+T+E+ + RK
Sbjct: 1 MKFENLLAEVGGFGKYQFCLMALLVIPRVTLPCHFLLNN--FIAAIPSHHCDISSLSADGIFGN--LTQEERLTVGVPAQEDGTPASCHMFSHPQFQLLINSSSSSDLPVVECQNGWRFDNSTFKSTLATEFDLVCDRRGLNKATATIFFAGVMIGA--AIFGWLTDRFGRKRMLMLAYLISITFGVASAFAQSFIVFAIMRFFTGMGLTGISIISIVLCIEWADIAHRTIAGVMISLDWSLSCMILSGVAYLVNDWRALILTVTAPIALAMITWRWLPESARWLIANGKLEEAHFYLSKCASVNNRQHNLRDIKPETLANVIIADRGDRTYSYLDLVRSSKMRKLAMLTGITWFG-VAFTYYGISFNISGFGLNLYLTQFIYGAIELPSKLVAYVCLDKLGRRYSQVGTMITTGVCIGITVLIPRVLWVPCTVIAVLGK--GFSEASFTCVF-LYTTELYPTVLRQNGLGYSSFIGRVGVSLAPLVSLLDEVWLPLPQVLFCSVAIVAGLLA-LLLPETHNVRLPETIEDIEKTRK 526
BLAST of slc22a-5 vs. Ensembl Zebrafish
Match: slc22a7a (solute carrier family 22 member 7a [Source:ZFIN;Acc:ZDB-GENE-050506-52]) HSP 1 Score: 131.339 bits (329), Expect = 3.827e-32 Identity = 136/541 (25.14%), Postives = 238/541 (43.99%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFN-QTQLTWTVKECQA------IARSENGT---------------------------NHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLG-TGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLM----NXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-----SLIITKQKLGNITDIFGSKIMRLKMFVL---IFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRK 1582
M +E+ + EI G +F L L L + I + FI P + C P + + + KE A I R+ +G+ N ++ C+N W Y+++ T+T +TE++LVC+ KK + T FF+G+++G + DK GR +I ++ + + I F+++ + + R L G TG + E +K R+ + + +G ML+ LAY +DW RHL+ + L+ + ++ +PES RWL G+ ++A L+ AK NGK K D + I + N + + + +L+ VL IF ++ +Y+G+S N + NI+L FI G++E ++ ++ RR + +I + LN S + V + + IGK A+ I +Y +E++PT +R + IA I AP + ++ Y +S + SG ++ F LPET LP+ + + E R
Sbjct: 1 MRFEDVLREIGGFNKFQFLVLYILWLPRVILPLHFLLHNFISGVPPHHCALPRLDGRFSASGAEKEELAQIVALGIPRNSDGSYSSCKMYTMPMDFDLNGDLSVLYGNRSNVSVPCQNGWVYDRSQFTSTTATEWDLVCDNKKLNQALATFFFIGVTMGAVVFGQLSDKFGRKPMIQVSFVSSAVFGIIEAFSSSYVMFAIARTLCGFALTGMSITTVALCVEWTDVKHRTFTGTIISLGWSVGNMLLALLAYLIRDW---RHLILVVTSPCLVGIIAWWWIPESARWLLANGRVEEAQKYLINCAKMNGKYSYTKKLDIENLKKITIAEDSNKNHSYLDLVRTPKLRKIVLCSGIFWFA-VAFTYYGISFNITGFGLNIYLTQFIYGVIEVPAKVGTYLTLDRIGRRNGQAWSLIIAGALIGLN---SVIPTEFAAVRTGIAVIGKGFSEAAFTIAFLYTSELYPTVLRQCGLGYTSFIARIGGSLAPMVILFEDIWHYGPPVVFSATAVFSGCVV-FLLPETTNVQLPENILDVEEGRH 533
BLAST of slc22a-5 vs. Ensembl Zebrafish
Match: oct2 (organic cation transporter 2 [Source:ZFIN;Acc:ZDB-GENE-080204-92]) HSP 1 Score: 129.028 bits (323), Expect = 2.166e-31 Identity = 122/442 (27.60%), Postives = 209/442 (47.29%), Query Frame = 2
Query: 326 NGTNHTIYC-RNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTM-----FFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGL-GTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-SLIITKQK---LGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSML-INFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP----SINGIDEFIPYFSCSCYSVMC-LISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENN 1597
N + H C W +N+ TI TEF+LVC + ++ +N + FF+G V ++A D+ GR ++ + C+ F+ L++ R L G G + E R + Y LG +L+P LAY WR L + +F + ++++PESPRWL K K+A++ + IAK N + PE+ + L+I KQ+ + D+F + MR F+LI+ T +V + GL + N+FL+ I ++E TG + + + ++ RR M +NF+ + CL + F + +S + T+ +G+ A+ + E++PTP+RN+ + + + I V AP + I + +P Y VM L SGL++ LPE KG LP+T+++ LR ++
Sbjct: 104 NNSTHLSACNEGWTFNEN--RTTIVTEFSLVC-EDSWLADLNQVSLAGGFFIGALVTGYLA---DRFGRKSCFIASIFGLGVSGTCIIFSPYYPLLLFFRCLQGFFAKGAWTATYVLIIEFFGSNNRKFVSVMSRTFYSLGLVLLPALAYYIPSWRNLQLAMTLPTFIFLIYHWVIPESPRWLLSQRKTKEALSIVKSIAKCNKRSLPEDFHEMDLLIEKQEEIMRPSYKDLFKTPKMRKHTFILIYAWFTGAVVFQGLVLRLGITGDNVFLDFLISAVVELPTGLIFYFLVDRIGRRPLMATVNFIGGAACLAV----PFISPNISWLRRTIAIVGRLAVAIGNETVNFANTELYPTPLRNLGVSVCSSASDIGAVVAPFILYRLASIWQELPLL---VYGVMSVLYSGLVM--LLPEMKGVDLPETVDDVENLRSRHKRK 530
BLAST of slc22a-5 vs. Ensembl Zebrafish
Match: slc22a6l (solute carrier family 22 member 6, like [Source:NCBI gene;Acc:404609]) HSP 1 Score: 128.257 bits (321), Expect = 5.375e-31 Identity = 112/467 (23.98%), Postives = 220/467 (47.11%), Query Frame = 2
Query: 236 TPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLG-TGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIIT---KQKLG------NITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENN 1597
TP ++ + N ++ W +++A +E T C + W YN T+M++TI TE++LVC+ + + T + G+ VG + D+ GR L+ ++ + I C+ F+T+ + + R G+ +G + + E + + R++ Y G +++ +AY +DWR L+ + + +L + ES RWL + K ++A+ NL +A+ NG+ +K D ++ K+++ + D+ + MR L V + S +Y+GLS++ +I+L I G ++ + I S L RR S ++ + +++N + ++ ++L IGK L ++ C +Y E++PT IR + + +A + AP + + + P+ Y ++SG+ FFLPET PLP T+++ ++ N+
Sbjct: 86 TPQWQILS--LNTSESLWD----ESMAETE-----TQSCEDGWFYNMTEMSSTIITEWDLVCDYRALKQMSQTTYMGGVLVGAIVFGGLSDRFGRRVLLLISNLMMAIGGTCVAFSTSFTMFCVFRVCCGMALSGLVLNSFSLIVEWIPTRVRTVVGTGTGYCYTTGQLILAAVAYCIRDWRWLTLAVSLPFYVSFLYSWWFLESARWLVLTKKPEQAVKNLKTVARINGRSAEGDKIDLEMLQESMKKEMACSKGSYSALDLLRTSTMRTITICLSAVWFSTSFAYYGLSMDLQKFGVSIYLIQIIFGAVDIPAKIIVTICMSMLGRRPSQCGALVLAGIMILINLLVP---SDLQMLRTSLAVIGKGCLAASFNCCYLYAGELYPTVIRQSGMGWVSMMARFGAMVAPMVLLLGDDYPWIPGFIYGGAPIVSGIFA-FFLPETLSQPLPDTIQDIDDRGLARTNS 537
BLAST of slc22a-5 vs. Ensembl Xenopus
Match: emc2 (ER membrane protein complex subunit 2 [Source:Xenbase;Acc:XB-GENE-484487]) HSP 1 Score: 153.295 bits (386), Expect = 1.499e-39 Identity = 139/530 (26.23%), Postives = 237/530 (44.72%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN---------------------------------WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKL-----GNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSI---FIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
+Y++A + + F V LS + S VF+ TP ++C P W +I R + + CR W Y+K+ +TI TE+NLVC L ++FFVG+ +G+F++ D+ GR +++ + + +I F+ N + L + G+G Y L EI+ R +++ I Y +GYML+P AY +DWR L L L ++++PESPRWL G+F++A + AK NG P++ F+ + +QK D+ ++ +R+ F+ I + ISV YFGLS+N L + ++N F+ ++E +AW++ RR S ++ V L+ F + I+ L +GKF +T+A+ + +Y E++PT +RNM + + + SI + + + D F+P+ +V+ + L LPE+ G PLP T+EE
Sbjct: 3 DYDQATAFLGEWGPFQVSVFFLLSASIIPNGFTGLSAVFLAATPEHRCHVPESANLSAAW---RNASIPRQDGQDSQ---CRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYSKSLYLSTIVTEWNLVCENDWKGPLTTSLFFVGVLIGSFVSGQMSDRFGRKKVLFATMAVQTGFSIIQVFSVNWEMFTALFIIVGMGQISNYVAAFILGAEILDKSVRIIFSTLGVCIFYAIGYMLLPLFAYFIRDWRTLLLALTIPGLFCIPLWWIIPESPRWLISQGRFQEAEDIIRKAAKKNGITPPDSIFNFTELQEQKELTHKSHTFLDLLKTRNIRIITFLSILLWMIISVGYFGLSLNTPNLHGDPYVNCFLSAIIEVPAYVIAWLLLRSFPRRYSTASTLVLGGVVLL---FIQLVPQELGILSIVLVMLGKFGITSAFSMVYVYTAELYPTVVRNMGVGASSMASRMGSILSPYFVYLGAYDRFLPFILMGSLTVLIGMFTLC----LPESHGMPLPDTIEE 519
BLAST of slc22a-5 vs. Ensembl Xenopus
Match: emc2 (ER membrane protein complex subunit 2 [Source:Xenbase;Acc:XB-GENE-484487]) HSP 1 Score: 153.295 bits (386), Expect = 1.539e-39 Identity = 139/530 (26.23%), Postives = 237/530 (44.72%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN---------------------------------WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKL-----GNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSI---FIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
+Y++A + + F V LS + S VF+ TP ++C P W +I R + + CR W Y+K+ +TI TE+NLVC L ++FFVG+ +G+F++ D+ GR +++ + + +I F+ N + L + G+G Y L EI+ R +++ I Y +GYML+P AY +DWR L L L ++++PESPRWL G+F++A + AK NG P++ F+ + +QK D+ ++ +R+ F+ I + ISV YFGLS+N L + ++N F+ ++E +AW++ RR S ++ V L+ F + I+ L +GKF +T+A+ + +Y E++PT +RNM + + + SI + + + D F+P+ +V+ + L LPE+ G PLP T+EE
Sbjct: 3 DYDQATAFLGEWGPFQVSVFFLLSASIIPNGFTGLSAVFLAATPEHRCHVPESANLSAAW---RNASIPRQDGQDSQ---CRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYSKSLYLSTIVTEWNLVCENDWKGPLTTSLFFVGVLIGSFVSGQMSDRFGRKKVLFATMAVQTGFSIIQVFSVNWEMFTALFIIVGMGQISNYVAAFILGAEILDKSVRIIFSTLGVCIFYAIGYMLLPLFAYFIRDWRTLLLALTIPGLFCIPLWWIIPESPRWLISQGRFQEAEDIIRKAAKKNGITPPDSIFNFTELQEQKELTHKSHTFLDLLKTRNIRIITFLSILLWMIISVGYFGLSLNTPNLHGDPYVNCFLSAIIEVPAYVIAWLLLRSFPRRYSTASTLVLGGVVLL---FIQLVPQELGILSIVLVMLGKFGITSAFSMVYVYTAELYPTVVRNMGVGASSMASRMGSILSPYFVYLGAYDRFLPFILMGSLTVLIGMFTLC----LPESHGMPLPDTIEE 519
BLAST of slc22a-5 vs. Ensembl Xenopus
Match: bub1b (BUB1B, mitotic checkpoint serine/threonine kinase [Source:Xenbase;Acc:XB-GENE-1010857]) HSP 1 Score: 142.124 bits (357), Expect = 1.204e-35 Identity = 138/536 (25.75%), Postives = 246/536 (45.90%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQT--QLTWTV--------------KECQAI-----ARSENGTNHTI---------YCRN-WKYNKTDMTNTISTEFNLVCNKKK----YVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSG-LGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQ----KLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSI----NGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRK 1582
++E + I + F + L ++ + S IVF+G P Y+CV + + WT+ +C + S N TN ++ C++ W YN T +++ TEFNLVC + + +N FF+G + +IA D+ GR + +++ I I + FA N L++ RF+ G + G G + E V ++ R Y + +G +L+ G+AY WR L + F Y+ +PESPRWL + +A + IAK NGK+ P+ +SL ++ ++ + D+ + +R +L+++ T +V Y G ++ + NI+ + FI L+E + + + ++ RR L+ +I + ++ +F S +I TL + + +T +Y + + E++PT IRN+ I + + + V P I I + +P ++V+ +SG+L+Y FLPETKG LP+T+EE L K
Sbjct: 3 TFDELLEHIGEFDAFQKQIFILLCFISVVFSPIYVGIVFLGFVPDYRCVSAGIPEPSNECEWTLNYTGPNGSTDSLYMSQCYQYDVDWNSTSLNCTNSSLNITSKLPITNCKDGWDYNTTG--SSLVTEFNLVCGDSWKLDFFQSCVNIGFFIGGLISGYIA---DRFGRKPFLISSILITGIFGILMAFAPNYPLVVTFRFIQGFVSKGCWLSGYILVAEFVGLEHRRTVGIVYQAAFTVGLLLLSGVAYVLPHWRWLQMTVTIPYFFFLAYYWCVPESPRWLISQNRKAEAKAIIHTIAKKNGKMVPDF-LESLTADEEAGEKQVPSFLDLVRTPQIRKHTLILMYIWFTCAVVYQGSIMHMGSTAENIYFDFFISALVEFPSAILIIVTVDRVGRRYPWLVCCIITGITCLIT---AFIPHGYSWLIITLSCVSRMGITVSYEMVCLVNAELYPTFIRNLGIMVCSSMCDLGGVITPFIVYRLAAIWQELPLI---VFAVLATVSGILVY-FLPETKGRALPETIEEAENLHK 525
BLAST of slc22a-5 vs. Ensembl Xenopus
Match: slc22a4 (solute carrier family 22 (organic cation/zwitterion transporter), member 4 [Source:NCBI gene;Acc:394948]) HSP 1 Score: 141.739 bits (356), Expect = 1.387e-35 Identity = 129/530 (24.34%), Postives = 238/530 (44.91%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN---------------------------------WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYN-----GKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSI---FIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
+Y+EA S + R+ + LS + + S++F+ P ++C P W +I R + + CR W Y+K+ +TI TE+++VC L ++FFVG+ +G+F++ D GR +++ + + + +I F+T+ + + + G+G Y L TEI+ R +++ I + +GYM++P AY +DWR L L L ++++PESP+WL G+ ++A + AK N IF + + L +++ + D+ + +R+ + +F+ ISV YFGLS+N L + ++N F+ ++E +AW++ RR S ++ V L+ F + I+ L +GKF +T+A+ + +Y E++PT +RNM + + + SI + + + D F+P+ +V+ + L LPE+ G PLP T+EE
Sbjct: 3 DYDEATSFLGEWGRYQFMIFFLLSASIIPNGFNGMSVMFLAGIPEHRCHIPESANLSAAW---RNASIPRQDGQDSQ---CRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYSKSLYLSTIVTEWDIVCENDWKGPLTTSLFFVGVLLGSFVSGQLSDSFGRKKILFVTMAIQTGFSIVQVFSTSWEMFAIFFLIVGMGQISNYVAAFILGTEILGKSARIIFSTLGTCIFFAIGYMMLPLFAYFIRDWRTLLLALTIPGLFCIPLWWIIPESPQWLICKGRIEEAEVIIRKAAKINRVPAPAVIFKTTELEDLAERQKRSYTLLDLVKTFNVRIITIMTVFLWMIISVGYFGLSLNTPNLHGDPYVNCFLSAIIEVPAYVIAWLLLRSFPRRYSTASTLVLGGVVLL---FIQLVPQELGILSIVLVMLGKFGITSAFSMVYVYTAELYPTVVRNMGVGASSMASRMGSILSPYFVYLGAYDRFLPFILMGSLTVLIGMFTLC----LPESHGMPLPDTIEE 519
BLAST of slc22a-5 vs. Ensembl Xenopus
Match: slc22a4 (solute carrier family 22 (organic cation/zwitterion transporter), member 4 [Source:NCBI gene;Acc:394948]) HSP 1 Score: 136.346 bits (342), Expect = 1.150e-33 Identity = 134/537 (24.95%), Postives = 246/537 (45.81%), Query Frame = 2
Query: 104 EMNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN---------------------------------WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYN-----GKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELR 1579
E +Y+EA S + R+ + LS + + S++F+ P ++C P W +I R + + CR W Y+K+ +TI TE+++VC L ++FFVG+ +G+F++ D GR +++ + + + +I F+T+ + + + G+G Y L TEI+ R +++ I + +GYM++P AY +DWR L L L ++++PESP+WL G+ ++A + AK N IF + + L +++ + D+ + +R+ + +F+ S+ YFG+S+N L + FLN F+ +E + AW++ ++RR SM + L+ V L+L + I+ + L +GKF +T A+ + +Y E++PT IRN + I + I +V +P + + +PY +V +G+L+ FF PET G PLP+T+E+ ++
Sbjct: 2 ERDYDEATSFLGEWGRYQFMIFFLLSASIIPNGFNGMSVMFLAGIPEHRCHIPESANLSAAW---RNASIPRQDGQDSQ---CRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYSKSLYLSTIVTEWDIVCENDWKGPLTTSLFFVGVLLGSFVSGQLSDSFGRKKILFVTMAIQTGFSIVQVFSTSWEMFAIFFLIVGMGQISNYVAAFILGTEILGKSARIIFSTLGTCIFFAIGYMMLPLFAYFIRDWRTLLLALTIPGLFCIPLWWIIPESPQWLICKGRIEEAEVIIRKAAKINRVPAPAVIFKTTELEDLAERQKRSYTLLDLVKTFNVRIITIMTVFLWLITSIGYFGISLNTPNLHGDPFLNCFLLAAIEVPSNIFAWLLLRYISRRYSMCGSLLLGGVVLLLIQLVPL---DLQILSTVLVMVGKFGVTAAFSMVYVYTAELYPTVIRNTGVGIGSVSSRIGSVISPYFVYLGAYNRLLPYILMGSLTVA---NGILVLFF-PETFGKPLPETIEQTQNIK 525
BLAST of slc22a-5 vs. Ensembl Mouse
Match: Slc22a5 (solute carrier family 22 (organic cation transporter), member 5 [Source:MGI Symbol;Acc:MGI:1329012]) HSP 1 Score: 167.162 bits (422), Expect = 1.487e-44 Identity = 142/530 (26.79%), Postives = 244/530 (46.04%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN---------------------------------WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLY-TNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-----SLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
+Y+E + + F L LS + + SIVF+ TP ++C+ P + L+ + +++G CR W+Y+K +TI TE++LVC L ++FFVG+ +G+FI+ D+ GR ++ L + + + F+ N + +L L G+G Y L TEI+S R ++ T I Y G+M++P AY +DWR L L +L ++ +PESPRWL G+ K+A + AK NG + P FD L TK +L +I D+ ++ +R+ + I + TISV YFGLS++ L +I++N F+ +E +AW++ L RR S+ + L+ F + + + L +GKF +T+AY + +Y E++PT +RNM + + + + ++ +P + D F+PY +++ I + F PE+ G PLP T+++
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVP--HTVNLSSAWRNHSIPLETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQESCLDGWEYDKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSELQDLNSTKPQLHHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLL---FMQLVPSELFYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAI----LTLFFPESFGVPLPDTIDQ 523
BLAST of slc22a-5 vs. Ensembl Mouse
Match: Slc22a21 (solute carrier family 22 (organic cation transporter), member 21 [Source:MGI Symbol;Acc:MGI:1929481]) HSP 1 Score: 154.451 bits (389), Expect = 4.843e-40 Identity = 123/426 (28.87%), Postives = 211/426 (49.53%), Query Frame = 2
Query: 356 NWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLY-TNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXX---XXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPE--------NKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRK 1582
W+Y+K +TI TE++LVC L + F+VG+ +G+FI+ D+ GR ++ L + + F+ N + LL L G+G Y L TE++S R ++ T I + G+M++P AY ++WR R L+ L L L +PESPRWL G+ K+A + AK NG + P NK K + +I D+ + +R+ + I + TISV YFGLS++ L+ NI++N F+ +E +AW++ ++RR SM + + L+L + + +TL +GKF +T+AY + +Y E++PT +RNM + + + + ++ +P + D +PY +++ I I F PE+ G LP+T++E +++K
Sbjct: 116 GWEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIREWR--RLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLL---VQLVPSDLHYLSTTLVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILTAI----ITLFFPESSGVSLPETIDEMQKVKK 532
BLAST of slc22a-5 vs. Ensembl Mouse
Match: Slc22a4 (solute carrier family 22 (organic cation transporter), member 4 [Source:MGI Symbol;Acc:MGI:1353479]) HSP 1 Score: 144.436 bits (363), Expect = 1.352e-36 Identity = 139/542 (25.65%), Postives = 244/542 (45.02%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN---------------------------------WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXX-XXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIIT-----KQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSML-INFLICSVCLMLN------NFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELR 1579
+Y+E I+ + F L LS + + S+VF+ TP ++C+ P + L+ + + +++G CR W+Y+K +TI TE+NLVC L ++FFVG+ G+F++ D+ GR +++ + + + F+TN + +L + G+G Y L TEI+S R +++ + +GYM++P AY +DWR+ + P LF ++ +PESPRWL +F +A + AK N + P FD L + KQ+ I D+F ++ + + + + SV YF LS+N L +++LN F+ GL+E AW++ L RR + + F V L++ NF S L +GKF +T+A+ + ++ E++PT +RNM++ I + + ++ AP + + +PY +V+ I I F PE+ G LP+ LE+ ++R
Sbjct: 3 DYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVP--DTVNLSSSWRNHSIPLETKDGRQVPQSCRRYRLATIANFSAMGLEPGQDVDLEQLEQESCLDGWEYDKDIFLSTIVTEWNLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFSTNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRIIFSTLGVCTFFAIGYMVLPLFAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFAEAEQIIQKAAKMNSIVAPAGIFDPLELQELNSLKQQKVIILDLFRTRNIATITVMAVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLIQVVPEDYNFVSI----------GLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGI----ITLFFPESFGVTLPENLEQMQKVR 528
BLAST of slc22a-5 vs. Ensembl Mouse
Match: Slc22a3 (solute carrier family 22 (organic cation transporter), member 3 [Source:MGI Symbol;Acc:MGI:1333817]) HSP 1 Score: 136.732 bits (343), Expect = 6.244e-34 Identity = 114/435 (26.21%), Postives = 217/435 (49.89%), Query Frame = 2
Query: 302 CQAIARSENGTNHTIYCR-NWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNF-IAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGL-GTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNIT--DIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP----SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNEL 1576
C + N + + C +W+Y +T +TI ++F+LVC+ + L + +G G F + D+ GR+ + ++ I + + FA N + ++ RFL G+ G G +TEIV K+R + + + LG +++PG+AY T W+ + + LF L Y+++PESPRWL + +KA+ L +AK NGK N + + +T +++ N + D+ + MR +L+F T +V Y GL + + N++++ FI GL+E + + +L RR+ + ++ V ++ +F + + +T+ ++G+ +T A+ I + +E++PT +RN + + G+ + AP + I +P + ++ + G L+ LPETKG LP+T+E+ +L
Sbjct: 106 CDPLTAFPNRSAPLVSCSGDWRYVETH--STIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSN-YSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYIDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVT---AFLPEGIPWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLI---IFGILASVCGGLV-MLLPETKGIALPETVEDVEKL 530
BLAST of slc22a-5 vs. Ensembl Mouse
Match: Slc22a30 (solute carrier family 22, member 30 [Source:MGI Symbol;Acc:MGI:2442750]) HSP 1 Score: 125.946 bits (315), Expect = 2.542e-30 Identity = 131/558 (23.48%), Postives = 254/558 (45.52%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLT----------------------WTVKECQAIARSE------NGT------NHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICG---DKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKI-YQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXX-XXESPRWLGIGGKFKKAITNLLLIAKYNG----------KIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTT-AYCICDMYLNEVFPTPIR--NMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE-GNELRKGNENNYCNMILK 1618
M ++E ++++ RF +L + + + + I F P+++C PI + + + +C+ A+ + NGT T C + W Y++++ +TI TE++LVC + ++ F +G+ +G I CG D+ GR ++ A++ I C+ FA + ++ LLRFL+G+ I + E S K + +GYM++ GLA+ + WR + M+ P+ F+L + ES RWL + K +K + L +A NG ++ + + L K+K + D+F + I+R ++ VL F+ ++S FGLS++ LS+NI L F+ L + + + + RR++ L+ + + ++ F + I+++TL + AL++ C+ ++++NE+ PT +R M + + G + +F AP + + Y ++ G + F LPETK PLP ++ + GN+ ++ + + I+K
Sbjct: 1 MAFQELLNQVGSLGRFQILQISFVLFLVGLVVPHITMENFTAAIPNHRCWAPILDNDTASDNGSRILSQDDLLRISIPLDSNLRLDKCRRFAQPQWHLLHLNGTFSNETEPDTEPCVDGWVYDRSNFLSTIVTEWDLVCESQALNSVAKFSFMIGLFIGAII--CGHLSDRFGRKFILTCALLQFAITETCVAFAPSFFIYCLLRFLAGMSVEPISVNSHLLMLEWTSPKFLGMVAVLTSCAASIGYMILAGLAFLFRIWRHLQLAMSVPIFFFLILTRWMSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGNTLTMEVVEASMKNELEAAKRK-SSPRDLFHTPILRKRICVLSFMRYLFTISIFGLSLHLQHLSTNIILLQFLSSALGILISVIGHFVLNHMGRRITQLVLMSLRGIFMLTAVFVPQEMQTLRIIMATLAA----ALSSLCMCVSNLHINELLPTTLRATGMGVIAMFGNSGLF--LAPLFMLLATYSANLPWIFYGGFSILYGFSV-FLLPETKNQPLPDSIHDVGNDWKESRQAKEEDSIIK 548
BLAST of slc22a-5 vs. UniProt/SwissProt
Match: sp|Q9Z0E8|S22A5_MOUSE (Solute carrier family 22 member 5 OS=Mus musculus OX=10090 GN=Slc22a5 PE=1 SV=1) HSP 1 Score: 167.162 bits (422), Expect = 1.040e-43 Identity = 142/530 (26.79%), Postives = 244/530 (46.04%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN---------------------------------WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLY-TNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-----SLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
+Y+E + + F L LS + + SIVF+ TP ++C+ P + L+ + +++G CR W+Y+K +TI TE++LVC L ++FFVG+ +G+FI+ D+ GR ++ L + + + F+ N + +L L G+G Y L TEI+S R ++ T I Y G+M++P AY +DWR L L +L ++ +PESPRWL G+ K+A + AK NG + P FD L TK +L +I D+ ++ +R+ + I + TISV YFGLS++ L +I++N F+ +E +AW++ L RR S+ + L+ F + + + L +GKF +T+AY + +Y E++PT +RNM + + + + ++ +P + D F+PY +++ I + F PE+ G PLP T+++
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVP--HTVNLSSAWRNHSIPLETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQESCLDGWEYDKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSELQDLNSTKPQLHHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLL---FMQLVPSELFYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAI----LTLFFPESFGVPLPDTIDQ 523
BLAST of slc22a-5 vs. UniProt/SwissProt
Match: sp|O76082|S22A5_HUMAN (Solute carrier family 22 member 5 OS=Homo sapiens OX=9606 GN=SLC22A5 PE=1 SV=1) HSP 1 Score: 166.007 bits (419), Expect = 2.884e-43 Identity = 123/415 (29.64%), Postives = 210/415 (50.60%), Query Frame = 2
Query: 356 NWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-----SLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
W++++ +TI TE+NLVC L ++FFVG+ +G+FI+ D+ GR ++ + + + + F+ N + ++L L G+G Y L TEI+ R +++ I Y GYM++P AY +DWR L L +L ++ +PESPRWL G+F++A + AK NG + P FD L KQ+ NI D+ + +R+ + I + TISV YFGLS++ L +IF+N F+ ++E +AW++ L RR SM + L+ F + + + L +GKF +T A+ + +Y E++PT +RNM + + + + ++ +P + D F+PY +++ I + FLPE+ G PLP T+++
Sbjct: 116 GWEFSQDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLL---FMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAI----LTLFLPESFGTPLPDTIDQ 523
BLAST of slc22a-5 vs. UniProt/SwissProt
Match: sp|O70594|S22A5_RAT (Solute carrier family 22 member 5 OS=Rattus norvegicus OX=10116 GN=Slc22a5 PE=1 SV=1) HSP 1 Score: 160.999 bits (406), Expect = 1.421e-41 Identity = 141/530 (26.60%), Postives = 243/530 (45.85%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN---------------------------------WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLY-TNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-----SLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
+Y+E + + F L LS + + SIVF+ TP ++C+ P + L+ + +++G CR W+YNK +TI TE++LVC L ++FFVG+ +G+FI+ D+ GR ++ L + + + F+ N + +L L G+G Y L TEI+S R ++ T I Y G+M++P AY +DWR L L +L ++ +PESPRWL G+ K+A + AK+NG + P FD L K + +I D+ ++ +R+ + I + TISV YFGLS++ L +I++N F+ +E +AW++ L RR S+ + L+ F + + + L +GKF +T+AY + +Y E++PT +RNM + + + + ++ +P + D F+PY +++ I + F PE+ G PLP T+++
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVP--HTVNLSSAWRNHSIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGRDVDLEQLEQENCLDGWEYNKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFNGIVAPSTIFDPSELQDLNSKKPQSHHIYDLVRTRNIRIITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQHLPRRYSISAALFLGGSVLL---FIQLVPSELFYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAI----LTLFFPESFGAPLPDTIDQ 523
BLAST of slc22a-5 vs. UniProt/SwissProt
Match: sp|Q9WTN6|S22AL_MOUSE (Solute carrier family 22 member 21 OS=Mus musculus OX=10090 GN=Slc22a21 PE=2 SV=1) HSP 1 Score: 154.451 bits (389), Expect = 3.388e-39 Identity = 123/426 (28.87%), Postives = 211/426 (49.53%), Query Frame = 2
Query: 356 NWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLY-TNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXX---XXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPE--------NKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP---SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRK 1582
W+Y+K +TI TE++LVC L + F+VG+ +G+FI+ D+ GR ++ L + + F+ N + LL L G+G Y L TE++S R ++ T I + G+M++P AY ++WR R L+ L L L +PESPRWL G+ K+A + AK NG + P NK K + +I D+ + +R+ + I + TISV YFGLS++ L+ NI++N F+ +E +AW++ ++RR SM + + L+L + + +TL +GKF +T+AY + +Y E++PT +RNM + + + + ++ +P + D +PY +++ I I F PE+ G LP+T++E +++K
Sbjct: 116 GWEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIREWR--RLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLL---VQLVPSDLHYLSTTLVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILTAI----ITLFFPESSGVSLPETIDEMQKVKK 532
BLAST of slc22a-5 vs. UniProt/SwissProt
Match: sp|Q9LHQ6|OCT4_ARATH (Organic cation/carnitine transporter 4 OS=Arabidopsis thaliana OX=3702 GN=OCT4 PE=2 SV=1) HSP 1 Score: 145.976 bits (367), Expect = 1.941e-36 Identity = 116/462 (25.11%), Postives = 210/462 (45.45%), Query Frame = 2
Query: 218 IVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVG--MSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKI-YQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR--LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPEN---KFDSLIITKQKL------GNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRR-VSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTL 1558
++F P ++CV +C+ N + +W++ ++T+S E+ L+C K V L+ +FF G + G F + K+GR + + I I I F+ N W ++LRFL+G TG + TE + +R + + + + G ++ G+AY + WR + L + + ESPRW + GK +A+ + IAK NG+ P D + G++ D+ S +MR+++ + + + T+S+ Y+GLS+N L +N++LNVF+ + E + ++ K R+ +S+ + C CL+ F + V G +G F + Y + +Y+ E+FPT +RN ++ A + + AP + + E +P+ ++V L+ G L F+LPET PL T+
Sbjct: 70 MIFADQEPEWRCVG------------SDCRV-----GSLNCELDPSSWEWTAGKGSSTVS-EWGLICGDKYKVGLVQALFFAGCMIGAGVFGHLSDSKLGRKGSLTVVCIINAIFGIATAFSPNYWTYVVLRFLTGFSTGGVGLTAFVLATEPIGPSKRGVAGMSTFYFFSAGIAVLSGIAYVFRSWRELFIVSSLPSLLFLLIVIPFISESPRWYLVRGKVDEAMKLMHSIAKTNGRHIPAGVTLALDDDVENNNGERNTAVEGSLKDVILSPLMRMRLVISVAISFTVSIVYYGLSLNVGNLKTNLYLNVFVNAVSEMPAFAITAVLLDKYGRKPLSIGTQWFSCVFCLV--GFSVWGAGPWKSVRMVSGVLGIFGMAGTYNLLFIYIAELFPTVVRNAALGCATQAAQMGAILAPFVVVLGEELPF---GVFAVCGLVGGGLA-FYLPETLNKPLYDTM 507
BLAST of slc22a-5 vs. TrEMBL
Match: A0A0H3YK93 (Slc22a-5 OS=Schmidtea mediterranea OX=79327 GN=slc22a-5 PE=2 SV=1) HSP 1 Score: 992.26 bits (2564), Expect = 0.000e+0 Identity = 515/515 (100.00%), Postives = 515/515 (100.00%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDELYNCKTKL 1651
MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNFPLLFYLTYFLLPESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFNNIIVSIVISTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDELYNCKTKL
Sbjct: 1 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNFPLLFYLTYFLLPESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFNNIIVSIVISTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDELYNCKTKL 515
BLAST of slc22a-5 vs. TrEMBL
Match: A0A5J4NMU2 (MFS transporter, OCT family, solute carrier family 22 (Organic cation transporter), member 4/5 OS=Paragonimus westermani OX=34504 GN=DEA37_0006863 PE=4 SV=1) HSP 1 Score: 264.233 bits (674), Expect = 4.926e-77 Identity = 169/577 (29.29%), Postives = 275/577 (47.66%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVD-PIFNQTQLTW--------------------------TVKECQAI-ARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLM-NXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDS----------------------LIITK----------------QKLGNITDIFGSKI----------MRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCN 1606
M +E + +I G F++L ++ S+ + I ++I +I+F+ +TP + C D P + +TW + +C + R++ C NW Y++T M NT+ T+FNLVC+++ +V+ M + +VG IA D IGR +W I+I + PFA + L+ LLR GL + Y G+ ++E+V + R+ + N YWIL+ GY+ G+AY +DW R +F +++ + ESPRWL + G+ K+A+ L IA +N P + FD L++ K +K N I GS +R + +L F+ +I++ YFGL + SF NIFLNV + GL+E T V W S L RR S I ++ V ++ + ++ S L GKF +T AYC+ D+Y++E++PT IRN+ +F ++ +A + + AP +N ++E Y C Y + +YFFLPETK CPL Q++++ E G E +C
Sbjct: 1 MEFESILVDIYGTGVFHMLYMVLCSISSFIGGLEIQTIIFMNYTPDFYCQDLPDVSNVTITWINKTLYDGLVNDRSVYSMNVNISNDTAIHQCWGMWKRTDTQEKVPFKCSNWTYDQTQMVNTVVTQFNLVCDQQFWVSWMEAAYLFFNAVGFVIAFVADIIGRRTTFLAFSVWGIVICLATPFANSPPLLFLLRCCRGLSSALSYIGINLVSELVPVTHRAAFGNVYWILWAFGYITCAGIAYLLQDWITIRLWSCSFLIVYLTYPIFIYESPRWLCMHGRNKEALVILKRIAWWNKAKLPADYFDRVDQFLHAEYAHHLGQATAEPEILVLEKDTETVNEIKTCVKLRPRKRANNDVIDGSSDKCFDMLRFPNLRNRTLILCFMQSSITIVYFGLVTDSSFALENIFLNVLMMGLMEVPTSFVGWWASEHLGRRSSTSILLILTGVTVLTTKLLG---PAIPVLRSILALSGKFFITVAYCVSDLYISELYPTTIRNIGLFTVIAVAGVASTVAPFVNKLNEINYYLPCLVYGTAAFVGTFSVYFFLPETKNCPLAQSVKQSEEFVHGKEKEWCE 574
BLAST of slc22a-5 vs. TrEMBL
Match: A0A504YHC0 (Uncharacterized protein OS=Fasciola gigantica OX=46835 GN=FGIG_02837 PE=4 SV=1) HSP 1 Score: 263.077 bits (671), Expect = 1.452e-76 Identity = 165/551 (29.95%), Postives = 274/551 (49.73%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDP---------------------IFNQTQLTWT----VKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXX-XXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLII--------TKQKLGNIT------------------DIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCN 1606
++E ++ I G + LA + S+ ++ +++ +++F+ + P + C D N+TQ+T ++C AI + H C NW ++ T M T+ ++FNLVC+++ ++ + + + ++G IA GD +GR R L V+ EII+ + PF + ++++R L GL +Y G+ ++E + RS Y N +W L+ +GY L G+AY T+DW R M LLFYL F+L ESPRWL + G+ ++A L +A +NG P+ FD + I TK+ + + D+F +R + V F H T++ Y+GL + SF + NIFLNVF+ GL E +G VAW + + RR S + ++ ++C+ N V + + + GKF L YC+ D+Y+ EVFPT IR S F+I+ +A +F AP +N + Y ++ + +L+ FLPET+GCPL QT+ E +L +G E +
Sbjct: 12 DFEIILNHIYGKGHYLRLAFIFCSITTLLAGLEVQTMIFMNYVPEHNCTDDRVVGDNATSRWVSKLSHHNGTDVNRTQMTKKQAELTEQCWAIISRQTEVTH-FPCTNWTFDTTVMLRTVVSQFNLVCDRQVWIPWLESSYLFANAIGYIIASFGDMVGRKRTFLLFVVLEIIVCLVTPFIRTVSWLLVMRILRGLSICLMYLGINLISEFAPVHLRSAYGNVFWSLWGVGYALCAGIAYLTRDWIQLRLWMCLFLLFYLPCPFVLSESPRWLCLRGQTEEAGRVLKRVAYWNGAHLPDEYFDKVDIFLHKQSYKTKENFSHSSLWKHPSDENDSGSRDTFRDLFTHPNLRFRCIVFCFAHTTVTFVYYGLITDNSFATENIFLNVFLMGLTEIPSGFVAWALCDYMGRRTSTSVLLVLTALCVGFTNLGDL---TYPDVRTVMATTGKFFLGVVYCVSDLYILEVFPTSIRTSSFFLIITVAGLFGAGAPFVNSLRRIARMLPTIIYCMLAVTGAILVLTFLPETRGCPLAQTVNESEQLVRGKERQWAE 558
BLAST of slc22a-5 vs. TrEMBL
Match: A0A183ATJ5 (MFS domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS10280 PE=4 SV=1) HSP 1 Score: 262.692 bits (670), Expect = 4.793e-76 Identity = 159/525 (30.29%), Postives = 273/525 (52.00%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVD---PIFNQTQLTW------------------------TVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXXXX-ESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNY 1600
N+E + I G + + + SM + I+ +++ S++F+ +TP + C D P+ N T + W + + C A+ + + C NW Y M T+ T+FNLVC ++ +V + ++F + +++G +A GD IGR +L +++I+ ++ PF + ++LR L GL G Y G+ L+E+V I RR+ Y N YW+L+ +GY+ G+AY T+DW R M Y+T+ + ESPRWL + G+ ++A L ++ + ++ + ++K + ++F + +RL++F+ FVH I+ +Y GL N +F + NIFLNV + GL E +G AW++S RR+S+ + + V + L +F I + + + GKF L+ AYC+ D+Y+ E+FPT R S F + +AS+F AP IN + F + Y + + +L++ LPET+ CPL QTL E L +GNE ++
Sbjct: 23 NFETILKHIYGKAYYIRVIFVFCSMTSLITGLEMQSLIFMHYTPEHNCTDRRIPL-NDTTVYWFSERPNIDLSRVNGTQLEAASGFDSREPCWAVFAGSSDEFIQLACSNWTYATRPMQQTVVTQFNLVCERRIWVPWLESVFLLSVAIGFLMASIGDTIGRKKLFLGLALFQIVTSLITPFTHTVEFHLILRCLRGLCPGLAYIGINILSELVPIHRRAAYGNVYWLLFSVGYVTCAGMAYLTRDWVQLRLWMCVFFTGYITFPFILCESPRWLCLQGRPEEATRILKRESEAMRRNLLSDQSNDQRSVRRK-DSFLNLFTYRNLRLRLFIFCFVHVAITTAYLGLITNNAFATDNIFLNVVLMGLSEMPSGIAAWLVSEYSGRRLSITLLLALTVVSVGLTELGAF---IHPVFRAVMAIGGKFFLSVAYCVIDLYVFEIFPTSTRTSSFFFVNTVASLFGALAPFINNLTRFSQFGPTLIYCAITALGAVLVFALLPETRDCPLAQTLAESERLVRGNERDW 542
BLAST of slc22a-5 vs. TrEMBL
Match: A0A2H1CK08 (Transporter, major facilitator family protein OS=Fasciola hepatica OX=6192 GN=D915_003087 PE=4 SV=1) HSP 1 Score: 261.151 bits (666), Expect = 7.565e-76 Identity = 164/551 (29.76%), Postives = 271/551 (49.18%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDP---------------------IFNQTQLT----WTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXX-XXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNIT--------------------------DIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCN 1606
++E ++ I G + L + S+ ++ +++ +++F+ + P + C D N+TQ T + ++C A+ + H C NW ++ T M T+ ++FNLVC+++ ++ + + + ++G IA GD +GR R L V+ EII+ + PF + ++++R L GL T +Y G+ ++E + RS Y N +W L+ +GY L G+AY T+DW R M LLFYL F+L ESPRWL + G ++A L +A +NG P+ FD + I K N T D+F +R + V F H T++ Y+GL + SF + NIFLNVF+ GL E +G VAW + + RR S + ++ ++C+ F + + V + + + GKF L YC+ D+Y+ EVFPT IR S F I+ +A +F AP +N + Y ++ + +L+ FLPET+ CPL QT+ E +L +G E +
Sbjct: 12 DFEIILNHIYGKGHYLRLVFIFCSITTLLAGLEVQTMIFMNYVPEHNCTDDRVVGDNATSRWVSKLSHHNGTDVNRTQTTKKQAESTEQCWAVINRQTEVTH-FPCTNWTFDTTVMLRTVVSQFNLVCDRRVWIPWLESSYLFANAIGYIIASFGDMVGRKRTFLLFVVLEIIVCLVTPFIRTVSWLLVMRILRGLSTCLMYLGINLISEFAPVHLRSAYGNVFWSLWGVGYALCAGIAYLTRDWIQLRLWMCLFLLFYLPCPFVLSESPRWLCLRGHTEEAGRVLKRVAYWNGAHLPDEYFDKVDIFLHKQTNKTKENFSHSSLWKHLSDENDSGSRDTIWDLFTHPNLRFRCIVFCFAHTTVTFVYYGLITDNSFATENIFLNVFLMGLTEIPSGFVAWALCDYMGRRTSTSVLLVLTALCV---GFTNLGELTYPDVRTVMATTGKFFLGVVYCVSDLYILEVFPTSIRTSSFFFIITVAGLFGAGAPFVNSLRRIARMLPTVIYCMLAVTGAILVLAFLPETRDCPLAQTVNESEQLVRGKERQWAE 558
BLAST of slc22a-5 vs. Ensembl Cavefish
Match: slc22a6l (solute carrier family 22 member 6-like [Source:NCBI gene;Acc:103025663]) HSP 1 Score: 150.214 bits (378), Expect = 1.003e-38 Identity = 104/416 (25.00%), Postives = 203/416 (48.80%), Query Frame = 2
Query: 356 NWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLG-TGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITK---------QKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEG 1567
W YN ++M++TI TE+++VC + + T++ G+ VG + D+ GR L+ ++ + + C FAT+ +L L RF G+ +G + + E + + R++ Y LG +L+ +AY +DWR L+ + + +L + ES RWL + + ++A+ NL +A++NG+ +K + ++ + QK N D+ + MR L V + S +Y+G++++ +I+L I G ++ + + + SKL RRVS ++ +C+++N + + ++L IGK L ++ C ++ E+FPT +R + + +A + + AP + + +P+ Y ++ G+ Y FLPET PLP T+++
Sbjct: 117 GWTYNMSEMSSTIITEWDMVCESRSLKPMGQTIYMAGVFVGAMVFGGLSDRFGRRNLLLISHLMMAVGGTCASFATSFYLFCLFRFFCGMALSGLVLNSFSLVVEWIPTRIRTVVGTFTGYCYTLGQLLLAAVAYTIRDWRWLTLAVSVPFYVSFLYSWWFVESARWLVLSNRPEQAVKNLKAVARFNGRREEGDKINIEVLQQSMKKEMACSQKSHNALDLIRTPTMRTITICLSAVWFSTSFAYYGIALDLQKFGVDIYLIQVIFGAVDIPSKVIITLSMSKLGRRVSQCSALIMAGICILVNLLVPY---EQQTLRTSLAVIGKGCLGASFNCCYLFSGELFPTVVRQSGMGWVSMMARVGAMVAPMVLLTGDSLPWLPGVIYGGTPILCGMFAY-FLPETLSAPLPDTIQDA 528
BLAST of slc22a-5 vs. Ensembl Cavefish
Match: si:dkey-119m7.4 (solute carrier family 22 member 13-like [Source:NCBI gene;Acc:103028301]) HSP 1 Score: 148.288 bits (373), Expect = 3.023e-38 Identity = 138/504 (27.38%), Postives = 233/504 (46.23%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNH------TIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLG-TGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLI---ITKQKLGN---ITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLN--RRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
MN++E ++ I G RF + + + + + + VF G P + C D + +T+ + + A TN T CR+ W+++K +T+ TEF+LVC+ + ++++ G+ VG + + D+ GR +I + + + + + FA N ++ +LLRF+ G +G I TE K R L + +GY+L+ G+AY +DWR L + +F ++LP+S RWL GK ++A+ + A N K N + + +QKL + D+ + MR + +L ++ + Y+GLS+N S NI+L I GL+E P I LN RR+S L + + +L F + +V + L +GKF +T + I +Y EVFPT +R I + A V AP I + P+ + +C + G L+ LPET PLP T+E+
Sbjct: 1 MNFDEVLARIGGFGRFQKILYVWICLPQIFLAFHMLVSVFTGAVPPHLCRDTKTHTHNFNFTLSQSASEACGSTHTNSSLSTHTTTACRDGWEFSKDVFLSTVVTEFDLVCDSATLNNIGSSIYMFGLLVGAVVFGVLADRYGRRIIILVGLALQAMFGVGAAFAPNFFIYVLLRFVVGTTVSGIIMNAFVLGTEWTGPKHRMLAGIITDYFFGVGYILLAGVAYLIRDWRKLQLAISAPGFIFIFYIWVLPKSARWLMANGKQEEAMDLICKAALINKKPLKGNDMEFQLNNCKVEQKLQRKHTVVDLVRTPQMRKQSLILFYLWFVNVLVYYGLSLNVSDFGMNIYLTQLIFGLVEM---PARTITLFTLNRSRRISQLSFLAVGGLACLLTIFIP---QNLPVVRTILAMLGKFGITASLSIVYVYSAEVFPTVVRQNGIGMGSMCARAGGVIAPIIYLLRRISPHAPMVVFG-LCPLVGALLTILLPETAHKPLPDTIED 497
BLAST of slc22a-5 vs. Ensembl Cavefish
Match: ENSAMXT00000002313.2 (solute carrier family 22 member 7-like [Source:NCBI gene;Acc:103025489]) HSP 1 Score: 139.428 bits (350), Expect = 5.888e-35 Identity = 149/541 (27.54%), Postives = 256/541 (47.32%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFN-VLALLT-LSMMACISSMDINSIVFIGHTPSYKC----VDPIFNQTQLTWTVKECQAIARSENGT-------------------NHT----IYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVG-NFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLG-TGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIFGSK------IMRL-KMFVLIFVHG----TISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLIS--GLLIYFFLPETKGCPLPQTLEEGNELRKGNE 1591
M +E+ + EI+G RF VL LL+ + +N+ +IG PS+ C +D LTW K +I R E+G+ N T I C N W ++ + +T+ST+++LVC+K++ + T+FF+G+ +G D+ GR ++ ++ + + + F+T+ + +LRF +GLG TG + + E V IK R L + + GYM++P +AYG +DW+ L+ + +L +T+ +PES RWL GK KKA L A N + K + + + L I GS+ +MR KM L F+ G ++ +Y+G+S N +++LN + G +E + + M ++ RR + L+ L++N F IV S +G +GK + A+ ++ +E++PT IR + + + AP I +DE + S ++C I+ G +I + LPET+G LP+T+E+ RK +
Sbjct: 1 MKFEDILGEIKGFGRFQKVLVLLSFIGRFTLPCHFLLNN--YIGAIPSHHCNIGYLDDEGLFENLTWEQKLTVSIPRQEDGSLASCHMFAEPQFQFLGAKSNFTDVPLIKCPNGWIFDNSTFLSTLSTQWDLVCDKREMNKAIATIFFIGVMLGAALFGSLSDRYGRKPMLLVSYVLGMSFAVASVFSTSFIMFAVLRFFTGLGITGIVIVSSVLIVEWVDIKSRKLVGMIDSMSWSFGYMVLPAMAYGVRDWKWLTITATSPLILAIITWRWIPESARWLIANGKIKKAQFYLERCAIIN-----KRKEATSSLKPEVLSCIVSEGGSRKYSYLDLMRTPKMRRLAFLTGLTWYAVASTYYGISFNIKGFGLDLYLNQLLYGFVEIPAKILIYHMLDRIGRRRTEAGVLLLAGCNLIIN---VFIPKDQWIVRSVIGVLGKGFASMAFSTLVLFSSELYPTVIRQNGMGWNSFMGRMGVAIAPLILLLDEIWGHMS---QIILCAIAVIGSVIAYQLPETRGRCLPETIEDVEGTRKDQD 528
BLAST of slc22a-5 vs. Ensembl Cavefish
Match: slc22a5 (solute carrier family 22 member 4-like [Source:NCBI gene;Acc:103026458]) HSP 1 Score: 136.346 bits (342), Expect = 7.371e-34 Identity = 137/555 (24.68%), Postives = 251/555 (45.23%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKC--------------------VDPIFNQTQLTW-----TVKECQAIARSENGTNHTIYCRN-----WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLI--ILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSL----IITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSI---NGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELR---KGN---ENNYCNMILKHDEL 1630
+YEE + + F ++ L L+ + + IVF G +PS+ C ++ Q++ W ++ A + + N T R WKY+ +TI +E++LVC ++ V ++ ++G +G+ ++ D+ GR +++ ++ E +I F+ + WL+ IL F+ TE++S R L+T ++ Y +GYM++P +A+ +DWR L R L +++ ++ +PESPRWL G+ K+A + AK N P+ F L I + ++ D+ + +R F+ + + I++ YFGLS+N S L + FLN F+ + E +A ++ RR +L FL +L + + L GKF T ++ + +Y E++PT +RN+ + + A I ++ AP I +++PY ++ I+ + FLPET G LP+T E+ + KG+ E + +++LK EL
Sbjct: 3 DYEEDTAFLGQKGPFFLIIFLLLNAIYISTGFHSFYIVFAGASPSHHCQVLDGNLSEEWIKASIPTEEINGKLEQSK-CWRYSLGAIQHFAAEGYNSSSVNFTDIARERCVEGWKYSTEVYHSTIVSEWDLVCEREWRVPFASSTIYMGYLLGSLVSGQLSDRFGRKKVLFASLALESVIIFAQSFSQS-WLVFCILYFFVGAFQISLYITAFVLGTEVLSTSLRVLFTTLGAFLHYCVGYMVLPWIAFVIRDWRTLLRVLSVLTVVYIPLWWFIPESPRWLISQGRVKEAEAIIKDAAKKNKVSAPDIIFRPLEGNKIPAPARKYSLIDVVKTSNIRFTTFMCLLLWMAINIGYFGLSLNTSNLIGDPFLNCFLSAVAEVPAYIIATLLLKSCPRR-PLLSGFLSIGGGFLL--LIQLIPERLHTLAVALEMAGKFGFTMSFTVVYIYTAEIYPTVLRNLGMGMCSSAARIGSITAPYIIFLGTYSKYLPYILMGSLTIGSSIANM----FLPETFGKVLPETCEQMQRCKWCQKGDVLMEEDRKHVVLKKQEL 548
BLAST of slc22a-5 vs. Ensembl Cavefish
Match: ENSAMXT00000010878.2 (pep primary_assembly:Astyanax_mexicanus-2.0:14:29265439:29284025:-1 gene:ENSAMXG00000010589.2 transcript:ENSAMXT00000010878.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 135.576 bits (340), Expect = 1.730e-33 Identity = 133/538 (24.72%), Postives = 238/538 (44.24%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFN-----------------QTQLTWTVKECQAIAR--SENGTN---------HTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFP--------ENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNN----FYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGN 1588
+YE+AI+ + + L L + S++F+ P++ C+ P N + +L+ + Q I R S G N C + W Y+K +TI TEF+LVC+ + ++++F+G+ G+F + D+ GR ++ ++ + I FA + + +L F+ GLG Y L TE++S R Y++ + + GYM++P +AY ++WR L L L++ ++ +PESPRWL G+ ++A + A+ NG + P E + ++ + NI D+ + +R +L V T+S+ YFGLS+N S L + ++N FI LE +W+ L R++S C V ++L F + + L GKF + + Y E++PT +RN ++ ++ + + AP + + Y +C+ S L FLPET PLP+T+++ + + N
Sbjct: 21 DYEQAIAFLGHWGPYQQLIFFLLCSSTIPNGFSAFSVIFLADIPAHHCLIPGANLSEEWIRASIPLNVVNGKHELSKCRRYNQEIIRNLSAQGFNPEDVNLTSVELEKCTDGWTYSKDVYQSTIVTEFDLVCDDEWKQPFTSSIYFIGVLCGSFFSGQISDRFGRKPVLFATMMVQTIFTFIQVFAPSWEVFSILFFIVGLGQISNYVAAFVLGTELLSGGVRVFYSSLGVCLFFAFGYMMLPLIAYLIRNWRMLLVALSVPGLIYIPLWWFIPESPRWLISQGRVEEAEAIVKNAARKNGVLPPDIIFKKSEEEEKNTKPQKTKPENNILDLMRTSNIRRTTLILFLVWLTLSMGYFGLSLNTSRLHGDSYVNCFISAALEVPAYITSWLSLRYLPRKLS-------CPVSMLLGGGVLYFIQLVPPDLPALSVALEMAGKFGMAIGTALMFAYTGELYPTVLRNTAVGSCAMVSRVGSAVAPYFIHLSVYHKYLPYILLGTLCIFSSLTT-LFLPETFRRPLPETIDQMQKRERIN 550
BLAST of slc22a-5 vs. Ensembl Sea Lamprey
Match: oct2 (organic cation transporter 2 [Source:ZFIN;Acc:ZDB-GENE-080204-92]) HSP 1 Score: 122.094 bits (305), Expect = 9.267e-30 Identity = 110/433 (25.40%), Postives = 201/433 (46.42%), Query Frame = 2
Query: 332 TNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGN-FIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGL-GTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPEN---KFDSLIITKQKLGN--ITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAP----SINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNE 1591
+ I C + W+++ T+ +EF+LVC + L + VG+ VG + D+ GR + ++++ + I + + FA N + +R L G+ G TE V +R + + + G +++ G+AY + WR L L ++ + Y+LLPESPRWL + ++A L IA NG+ +N F+ + +K GN I D+ S +R VL+ + V Y GL+++ + +++L + GL E + + ++ RR+ M + + + + + ++I + TLG +G LT AY + + NE++PT +RNM++ ++ I + AP + I +P + + +I G +I LPET G PLP+T E+ + K +
Sbjct: 121 SGRLIACDHGWEFDTEKTGLTLVSEFDLVCENAWLLDLSQALLNVGLLVGAILMGYVSDRYGRRWSLMVSIVMQTIFGVLVAFAPNYAAFVCMRTLQGIFNMGSWTTVFVTATEFVGSGQRRVVHMVLQMFFSFGVIMLSGIAYYLRTWRYLQLALTLPNVVLFSYYWLLPESPRWLISQNRKEQAFGVLKKIASVNGRELSDNIRKNFEEVTRADEKAGNPSIADLMRSAKIRKYTVVLMIYWFVVGVVYQGLAMSTGNIGDDVYLAFLMGGLAEIPGALMVIALIDRVGRRLPMCVAPGLSGLACLATALVPHDIGWLNITLVTLGRLG---LTMAYEMVTLVNNELYPTHLRNMAMSTCSSLSGIGGIVAPFVLYRLYTIWRHLPMV---IFGTLAIIGGFVI-LLLPETNGLPLPETTEDAENISKNQK 546
BLAST of slc22a-5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007122.1 (pep scaffold:Pmarinus_7.0:GL476962:153150:164773:-1 gene:ENSPMAG00000006444.1 transcript:ENSPMAT00000007122.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 83.9593 bits (206), Expect = 1.763e-18 Identity = 65/239 (27.20%), Postives = 112/239 (46.86%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACIS-SMDINSIVFIGHTPSYKCVDP------IFNQTQLTWTVKECQAIARSE--------NGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVG-NFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLG-TGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR 772
MN+++ + +I G +F ++ L T + IS +M + VF G TP++ C DP + + T T E A +E N + W Y+++ T+T+ TE++LVC + + +++F +G+ VG + DK GR +I +++ + + FA N + L RF+ G+ +G I TE I R L + +GYML+ +AY +DWR
Sbjct: 1 MNFDDVLKKIGGFGKFQMI-LYTWICLPHISIAMHMLVSVFAGATPAHFCRDPPGGHAPVPSATTAPPTAGESAAANGTERPRCGSRLNESGWQPCATGWDYDRSVFTSTVVTEWDLVCTRSYLNNVGSSIFMLGLMVGAPVLGTMADKYGRKSVILVSMAIQTAFGLGAAFAPNFVMYALARFMVGVAISGVIMNAFVLATEWTGIGERMLAGIATQQAFGVGYMLLAPVAYFIRDWR 238
BLAST of slc22a-5 vs. Ensembl Sea Lamprey
Match: slc22a6l (solute carrier family 22 member 6, like [Source:NCBI gene;Acc:404609]) HSP 1 Score: 83.1889 bits (204), Expect = 9.814e-18 Identity = 82/316 (25.95%), Postives = 144/316 (45.57%), Query Frame = 2
Query: 662 EIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXX-XXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDS-LIITKQKLGNIT---------DIFGSKIMRLKMFVLIFVH-GTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSV---CLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEE 1564
E +++K R+LY + Y G +++ LAY +DWR +H ++ + PES RWL + G +++A+ L +A NG+ + S L +++L T ++ +R + V+ V + Y G + + ++ FL I G ++ V ++ S L RR + + + S+ CL+ S + L +GK AL+ ++ +Y E+FPT IR + + +A + + AP + E +P S Y L++G L+Y FLPET PLP+T+EE
Sbjct: 2 EWIAMKDRTLYGMLSGVAYTTGQLVLVALAYYIRDWRHLQHSISAAFYVFFLCSWCTPESARWLVMRGHYERALHGLKRVAVINGRKREAAQLTSPLQYLRKELEEDTGPRRFYTMFNLLTIPALRRRTLVMSLVWCDDVFCWYAGFVVIVTRTCAHTFLLQVIYGAIDYPAKVVGLVVLSLLGRRATQAGSLAVASIASFCLLAIPAES------GTARTCLAVLGKGALSCSFNCAYLYTGEIFPTVIRQSGLGLCSTMARVGGMLAPLVIMAGESLPALPLSMYGSASLVAGSLVY-FLPETLNRPLPETIEE 310
BLAST of slc22a-5 vs. Ensembl Sea Lamprey
Match: SLC22A7 (solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971]) HSP 1 Score: 76.2554 bits (186), Expect = 1.766e-15 Identity = 78/319 (24.45%), Postives = 137/319 (42.95%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKC-------VDPIFNQT--------QLTWTVKECQAIA----RSENGTN----------HTIYC-RNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLG-TGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDW-RLSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQK 964
MN+EEA+S G RF + + L + + + FI TP ++C P+ N + Q W + + ++ R GTN + C W+Y++ T T+ T+++LVC K L T+F G+ +G+ + D+ GR + + + + +A + +RFL G+ +G I L E + R+ + + G M + LAY + W +L + + LT++ +PESPRWL + G+ ++A NL L A+ NG+ KF S + + +
Sbjct: 1 MNFEEALSAAGGFSRFQLWLTVLLLVPRLVLPWHLMVNNFISATPHHRCRLPDSPTAAPLDNGSGPAETWGGQPPWRDDDEEGLSACSLREAAGTNASESPLRNSSEAVPCPSGWEYDRRQFTETVVTQWDLVCEHKALNHLSLTLFMAGVMLGSLVFGYLSDRYGRRNALLGSYVLNAVTGTAAAWAPSFSSFTAMRFLLGVSLSGIIVNTLSLSVEWLDQGHRTFAGTSGGFAWSTGNMALGLLAYLLRGWQQLQLVVTSPIYFCILTWWFIPESPRWLLVRGRAREAHRNLSLCARINGRT----KFGSEVTVEAR 315
BLAST of slc22a-5 vs. Ensembl Sea Lamprey
Match: svopl (SVOP-like [Source:NCBI gene;Acc:492766]) HSP 1 Score: 61.2326 bits (147), Expect = 3.114e-10 Identity = 100/434 (23.04%), Postives = 172/434 (39.63%), Query Frame = 2
Query: 380 MTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICG---DKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSL---YTNNYWIL-----YVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFL---------------------------------SSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNE--VFPTPIRNMSIFIILGIASIFTVFAPSINGI--DEFIPYFSCSCYSVMCLISGLLIYFFLPETKG 1537
++ TI E+ L ++ V L+ TM F G + + CG D+ GR +++ L IW + F+ + LRFL G G G QG ++E + R + +W+L VL Y+++P L + W L R + + + +PES R+ K KA+ L IAK N P+ ++ GNI D+ + +R + GT +++Y+GL + S L S + + + E P + L RR SM ++ ++C + +Y N + ++ L + +T + I +Y E V+PT IR++ + A I + AP + + D IP C + +C+I +L + ET G
Sbjct: 71 ISPTIQCEWRL---QQWQVALVTTMVFFGFMLSS--GPCGFLADRYGRWKVLLLVTIWSSYWSGISSFSPTYGWFVFLRFLMGCGIGGQSQGFVLMSEFMPSTARGRVLPMSQVFWVLGSLLEVVLAYLILPTLGWA---W-LIRISTIPSFVLLIAFKFIPESARYQVSAAKPDKALLTLAKIAKMNKTTLPQGTLVE--PPAERRGNIWDLLDRQYLRTTLQTWPIWFGT-TLTYYGLILVSSELLERNQMCGDDSVTAIEEHIAFSEQESPCFCKQFKSEDYKTLLLSSFGEFLAIPFTTLTIDTLGRRRSMALSMILCGLL-----YYLLNICTTRMGLTVLLFFLRAVASTNFNIIYIYTVEVKVYPTNIRSLGLGSCSSTARIGAMIAPFVAQVILDISIPLALC-LFGTVCVICSVLAFTLPIETMG 486
BLAST of slc22a-5 vs. Ensembl Nematostella
Match: EDO46087 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR13]) HSP 1 Score: 133.65 bits (335), Expect = 1.100e-33 Identity = 126/497 (25.35%), Postives = 230/497 (46.28%), Query Frame = 2
Query: 140 GNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTG-KIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPEN--KFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLI-----CSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNY 1600
G + + LL LS++ +++ + +VF+ P + C++ N+T C + + C +Y T +I TE++LVC L+ ++ G +G + DK GR R+ H + ++ FA + LRFL+G G +I TE+V R + LG +++P +AY +DWR LS L +F L + +PES RWL I G+ +A LL IA NG P++ + + + G D+F ++ + + FVLIF+ ++ Y+GLS+N L+ +I++N F+ L+E F + + R L N+++ C C+ + S + + IGKF +T ++ + +Y E+FPT +RN+ + + + I + AP + + ++ + + ++GLL LPET PLP+T+++ ++ K N++++
Sbjct: 14 GPHQRRLYVLLCLSIVP--AAIQLLLLVFVAAQPHWICLNSSTNET--------CP---------KNKLQCTERQY--TSKYTSIITEWDLVCENAYKADLVQSLLMSGTLLGALMFGALADKYGRRRVWHTTLTGLVVFGFASSFAPTFKIYATLRFLTGFCIGGEILSAFVLATELVGPSYRGFAGIMAQCFFTLGLLILPMVAYLIQDWRTLSVVLSLPASVFILFFRYVPESARWLMIRGRVSEAENILLDIALKNGIAVPKSLLQVNHPFFVGSRYG-FFDLFCTRKIVKQTFVLIFIWFVNTLVYYGLSLNTKHLAGDIYMNFFLCSLME-FPAYLTCLFFVNWAGRRKTLFNYMVLAGLACMACMFVQPESS---PADRTLATVFAMIGKFGITASFALIYIYSAEIFPTVVRNVGLGVCSMSSRIGGICAPFVVFLGTYMRPLPMVIFGMCAFMAGLL-SLMLPETHKRPLPETMDD--KMFKANDSDF 481
BLAST of slc22a-5 vs. Ensembl Nematostella
Match: EDO45833 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRW4]) HSP 1 Score: 130.183 bits (326), Expect = 1.389e-32 Identity = 116/443 (26.19%), Postives = 206/443 (46.50%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQK---LGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNN---FYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRN-----MSIFIILG 1396
M+ ++ +S I G F L ++ I++ IVF+G P +KC Q T T+ + + ++ +W++ T +I +E++L+C K +L ++ F+G G FI D GR R++ ++ + ++ FA ++WL ++LR + G G +Y L L TE V RSL W+ + L + + GLAYG DWR ++ P L ++L+PES RW + + K+A L IAK NGK P + ++ +++ G I D+F + + +L F T ++ Y+G++++ L +++LN + L+E + L M + L+C +CL N F+S ++ +GKF ++ ++C + E+ PT IRN M++F LG
Sbjct: 1 MDIDKILSSIGGFGFFQKRNSFILGLVIFIATFQTVLIVFVGMEPPWKCA-----QDSTTCTLNGTFSSGDENYDSRCSMNRSDWEF--TSGFTSIVSEWDLICGKAAMASLAQSILFIGWIPGAFIIGKLSDMFGRTRMLFPSIAVVAVASLSCSFAQHLWLYLVLRAIIGFFEGGVYIVLYVLSTEFVGPAHRSLAGTLNWVFFTLSLITLDGLAYGLHDWRHLSIAVSVPALPLFFFWLVPESCRWQLVNNRCKEARQTLEHIAKLNGKNLPSDVMPAINNVEEEKSFRGGILDLFKPRQQLKQTLILWFSWLTNAMVYYGVTLSAGVLGGSLYLNFLLASLVE---------LPGNLFSIWFMNLLGLVCMLCLASANITLFFSQGPGHYQVIKIISAVLGKFCISISFCTIYVTSTELLPTVIRNIGMGSMAVFDQLG 427
BLAST of slc22a-5 vs. Ensembl Nematostella
Match: EDO27829 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T865]) HSP 1 Score: 128.642 bits (322), Expect = 1.810e-31 Identity = 129/503 (25.65%), Postives = 228/503 (45.33%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQ--GLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-----SLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRR----VSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNE 1573
+ ++A+ + G + + +S S + + F P ++CV + T T K A N + R+ W++ ++I TE++LVC+K Y T+ N++ F+ G +I GDK GR ++ VI+ + + FA W+ L R L G G G Y G + E + I+ RS+ W ++L ++ L Y WR LS LLF++ ++ P+S RW + GKF A L+ +AK G + + F+ + I ++LG+I D+F S+ M + V + + Y+G+S++ + + +++LN F+ L E + + + R+ SM + L V +L+ + + ++ I + I KF +T A+ +Y +E+FPT +RN ++ A I + AP + P ++ LI G+L LPETK PLP T+++ E
Sbjct: 3 LTADQAVEKAGGFGWYQLRVFAVISYAVIFCSCVLMVMTFSTAEPPWQCVAN--SSCNFTGTFKPGDA-----NYEKRCLMARDQWEFAIDAGFDSIVTEWDLVCSKSMYATIANSITFILWIFGAMAGSIIGDKFGRKIVVFPCVIFASLCGLASAFANKYWVFALFRALLGAGIGG-YSICGFVLVMEYIGIRHRSIVGFCVWYPWILALFMLALLGYLIPSWRTLSIITSAPGLLFFVFWWFTPDSLRWYLVKGKFDDAKKVLVDVAKGCGNNYTKQDFEFEEEHTFNIEHERLGDIRDLFHSRSMAHRTLVSWYCWLVSGLVYYGISLSSTTIGGDMYLNFFLSALFEGIGMAIGIPLLDRFGRKKTIVASMYVAALAAIVAALLSQYDDGSQAMLVGKIISAMVIAKFFVTIAFDGVYVYSSELFPTVVRNTAMGTSTSAARIGSFAAPFTVYSQKVHPMMPFGIMALNALICGILC-MTLPETKDKPLPDTVKQTEE 496
BLAST of slc22a-5 vs. Ensembl Nematostella
Match: EDO47316 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMR6]) HSP 1 Score: 125.176 bits (313), Expect = 7.828e-31 Identity = 124/499 (24.85%), Postives = 229/499 (45.89%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFV----GMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQ--GLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-----SLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGS--IGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTL 1558
+ ++A+ + G + + +S S + + F P ++CV + T T K A N + R+ W++ ++I TE++LVC+K Y T+ N++ F+ G G+ I+ DK GR ++ VI+ + + FA W+ L R L G G G Y G + E + I+ RS+ W ++L ++ L Y WR LS LLF++ ++ P+S RW + GKF A L+ +AK G + + F+ + I ++LG+I D+F S+ M + V + + Y+G+S++ + + +++LN F+ L E + + + R+ +++ + + ++ ++ S + +V + + I KF +T A+ +Y +E+FPT +RN ++ A I + AP + +P+ ++ LI G+L LPETK PLP T+
Sbjct: 3 LTADQAVEKAGGFGWYQLRVFAVISYAVIFCSCVLMVMTFSTAEPPWQCVAN--SSCNFTGTFKPGDA-----NYEKRCMMARDQWEFAIDAGFDSIVTEWDLVCSKSMYATIANSITFILWIFGAMAGSIIS---DKFGRKIVVFPCVIFASLCGLASAFANKYWVFALFRALLGAGIGG-YSICGFVLVMEYIGIRHRSIVGFCVWYPWILALFMLALLGYLIPSWRTLSIITSAPGLLFFVFWWFTPDSLRWYLVKGKFDDAKKVLVDVAKGCGNNYTKQDFEFEEEHTFNIEHERLGDIRDLFHSRSMAHRTLVSWYCWLVSGLVYYGISLSSTTIGGDMYLNFFLSALFEGIGMAIGIPLLDRFGRKKTIVASMYVAALAAIVAALLSQYDDGTMLVGKIISAMVIAKFFVTIAFDGVYVYSSELFPTVVRNTAMGTSTSAARIGSFAAPFTQKVHPMMPF---GIMALNALICGILC-MTLPETKDKPLPDTV 486
BLAST of slc22a-5 vs. Ensembl Nematostella
Match: EDO36597 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI67]) HSP 1 Score: 122.094 bits (305), Expect = 8.035e-30 Identity = 120/485 (24.74%), Postives = 224/485 (46.19%), Query Frame = 2
Query: 140 GNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLC---YLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFD-----SLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGS--IGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTL 1558
G + V A+++ + + C S + + F P ++CV + T T K A N + R+ W++ ++I TE++LVC+K Y T+ N++ F+ G +I GDK GR ++ VI+ + + FA W+ L R L G G G +C + E + I+ RS+ + ++L ++ L Y WR + + P L + ++ P+S RW + GKF A L+ +AK G + + F+ + I ++LG+I D+F S+ M + V + + Y+G+S++ + + +++LN F+ L E + + + R+ ++ + + ++ ++ S + +V + + I KF +T A+ +Y +E+FPT +RN ++ A I + AP + +P+ ++ LI G+L LPETK PLP T+
Sbjct: 16 GWYQLRVFAVISYAKIFC--SCVLMVMTFSTAEPPWQCVAN--SSCNFTGTFKPGDA-----NYEKRCLMARDQWEFAIDAGFDSIVTEWDLVCSKSMYATIANSITFILWIFGAMAGSIIGDKFGRKIVVFPCVIFASLCGLASAFANKYWVFALFRALLGAGIGG--YSICSFVLVMEYIGIRHRSIVGFCVFYPWILALFMLALLGYLIPSWRTLSIITSAPGLLFFVFWFTPDSLRWYLVKGKFDDAKKVLVDVAKGCGNNYTKQDFEFEEEHTFNIEHERLGDIRDLFHSRSMAHRTLVSWYCWLVSGLVYYGISLSSTTIGGDMYLNFFLSALFEGIGMAIGIPLLDRFGRKKTIAASMCVAALAAIVAALLSQYDDGTMLVGKIISAMVIAKFFVTIAFDGVYVYSSELFPTVVRNTAMGTSTSAARIGSFAAPFTQKVHPMMPF---GIMALNALICGILC-MTLPETKDKPLPDTV 485
BLAST of slc22a-5 vs. Ensembl Medaka
Match: si:dkey-166k12.1 (solute carrier family 22 member 13 [Source:NCBI gene;Acc:101165571]) HSP 1 Score: 147.132 bits (370), Expect = 9.344e-38 Identity = 138/510 (27.06%), Postives = 240/510 (47.06%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIF----NQT-QLTWTVKEC-QAIARSENGTNHTIYC-RNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLG-TGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPE----NKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSM----LINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFT----VFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGN 1570
MN+++ ++ I G ++ + + + + + + + +F G TP ++C D NQT L+ C A A + C R W Y+ ++ TE++LVCN+ +L ++++ G+ VG+ + D+ GR ++ L++ + + + + FA N + +LLRF G +G I TE KRR L + LGYML+ G+AY +DWR L + L +LP+S RWL + ++AI L A NG++ P K++ L +K+ + D+ + MR + +L ++ + Y+GLS+ S L +N+++ F+ GL+E + I +RR+S+ + L C + L + + V++ L +GKF +T ++ I +Y E+FPT +R I G++S+F V AP IN +D P + L+ L+ LPET PLP TLE+
Sbjct: 1 MNFDQILAAIGGFGKYQKILYIWICLPQILLAFHMMVSIFTGATPPHQCRDSFSTGAGNQTLNLSLPDASCFSADALPPGNRTERVPCGRGWVYSSEVFESSTVTEWDLVCNRAGLNSLGSSVYMSGLLVGSVVFGAMADRYGRRFVLLLSIALQTVFGVAVAFAPNFPVYVLLRFAVGTTISGVIINAFVLGTEWTCTKRRMLAGIITDYTFGLGYMLLAGVAYLIRDWRKLQLAISAPGFLLIFYIRVLPQSARWLLANDRTEEAIALLRKAALVNGRVLPPAVQVEKWEILGGSKRSHSAV-DLVRTPQMRKRTVILFYIWFVNVLVYYGLSLGVSRLGTNLYMTQFVFGLIEIPARSLVLIFL-PFSRRLSLSGFLAVGGLACLLMLTVPEDHP-------NVLTGLAMVGKFGITASFAIIYVYTAEIFPTVVRQTGI----GVSSMFARMGGVLAPIINMLDSHSPATPLIIFGTSPLLG-ALLALALPETADRPLPDTLEDAE 496
BLAST of slc22a-5 vs. Ensembl Medaka
Match: ENSORLT00000024218.2 (solute carrier family 22 member 7 [Source:NCBI gene;Acc:101170147]) HSP 1 Score: 144.05 bits (362), Expect = 1.223e-36 Identity = 137/533 (25.70%), Postives = 242/533 (45.40%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNV--LALLTLSMMACISSMDINSIVFIGHTPSYKC-VDPIFN-----------------QTQLTWTVKECQAIARSE-----NGTNHT----IYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFI-AICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLG-TGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGK------IFPENKFDSLIITKQ--KLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRK 1582
M +E ++E+ G RF + + LL + M +N+ FI PS+ C + P+ + Q + CQ A + NGTN T I C N W Y+ T +T++++++LVC+KK T+FF+G+ +G I D+ GR R + ++ I F+ N + + +RFL+G+G +G + E V IK R+ + + +++P LAY DWR L+ + L +T+ LPES RWL GK +A L A N + + PE +++ + K + + ++ RL + I G ++ +Y+G+S+N + NI+L FI G+ E +K+ RR++ + L+ +C+ N F +T+G++GK A+ +Y E++PT +R + +A I +P + ++E + + +S + I+GL FLPET+ LP+T+E+ + R+
Sbjct: 1 MKFENVLAEVNGFGRFQIRTILLLVIPRMTLPFHFLLNN--FIAAVPSHHCDISPLDDGDLFRNLSELEKLVVSIPAQQDGSSHSCQMFAEPQYHLVWNGTNSTDPLKIPCTNGWWYDNTTFKSTLASQWDLVCDKKSMNRATATIFFMGVMLGAAIFGYLSDRFGRKRTLLVSYIATTTFGFASAFSYNFPMFVAMRFLTGVGISGISIVSIVLCVEWVDIKHRTYVGVLMSLDWSFSTVVLPALAYFVNDWRSLTATVTAPLLAAMITWRWLPESARWLISTGKVDRAHFYLHQCATVNHREDFMADLKPEVLSKVILVEDENRKYSYVDLVKTPRMRRLALLTGIVWFG-VACTYYGISLNVTGFGVNIYLTQFIYGVTEVPAKAFIVFFLNKIGRRLTQVGTLLLTGLCIFCN---IFIPQDQVAARTTVGALGKMLAEAAFTTVFLYTTELYPTVMRQNGLGYSSFMARIGVSVSPLMMILEETWIHLPNTIFSAVAFIAGLSAS-FLPETRNIRLPETIEDVEQKRR 526
BLAST of slc22a-5 vs. Ensembl Medaka
Match: ENSORLT00000027238.1 (solute carrier family 22 member 5 [Source:NCBI gene;Acc:101164738]) HSP 1 Score: 144.05 bits (362), Expect = 1.229e-36 Identity = 147/535 (27.48%), Postives = 251/535 (46.92%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFN--VLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQ--LTWTV--------KECQAIARSENGTNHTIYCRN--------------------WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATN-IWLIILLRFLSGLGT-GKIYQGLCYLTEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLII----TKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIA---SIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRK 1582
NY +A++ + RF V LL S+M + ++VF+ PS+ C P N T+ LT + +E +R + R W Y+K +TI TEF+LVC ++ +T+FFVG+ +G+F + D+ GR ++ + + I F T IW IILL F++GLG L EI + R LY++ + +GYML+P AY +DW+ L L + + +++LPESPRWL G+ +A + + AK+N P N F+ + T+++ N+ D+ +R +L FV T+ Y+ LS N S L ++ +++ FI L+E ++I RR+S++++ + +V L L +S + TL + K++ TT + Y E++PT +RN + I+ S T F S++ +++PY + +V+ IS +FLPE+ PLP+T+E+ +E ++
Sbjct: 3 NYGDAVAFLGQWGRFQQAVFFLLCASIMP--NGFGAFTLVFMNDIPSHHCRVPESNLTEEWLTSVIPLTEVNGKQELSKCSRYRLDVVRNLSARGFIPHKDINLSDIELEGCVDGWVYSKDIYQSTIVTEFDLVCTEQWKQPFTSTIFFVGVLLGSFFSGPLSDRFGRKPVLFATMAAQTIFTFLSVFTTTWIWFIILL-FINGLGQISNFVAALVLGAEIFTGNVRVLYSSMGTCCGFAVGYMLLPLCAYFLRDWKSLLLALSVPCVAYIPLWWILPESPRWLLSQGRIAEAEAVVKMAAKWNKVQAPSNIFECNSVEKTDTQKEHYNVFDLLRHSRIRTTTLLLCFVLFTLITGYYCLSFNTSQLHTDPYISCFISALVEIPAYASSFIALRYFPRRLSIIVSLIAGAVPLYL---IPLVPEHLSSLSLTLEMVSKYSFTTGASLMFAYTTELYPTVLRNTATGTTTTISRMGSCITPFLLSLSVHYKYLPYVILATLAVVTAISA----YFLPESFKLPLPETIEQMHERQR 527
BLAST of slc22a-5 vs. Ensembl Medaka
Match: ENSORLT00000001522.2 (solute carrier family 22 member 5 [Source:NCBI gene;Acc:101164738]) HSP 1 Score: 142.895 bits (359), Expect = 2.659e-36 Identity = 147/532 (27.63%), Postives = 249/532 (46.80%), Query Frame = 2
Query: 110 NYEEAISEIQGNERFN--VLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQ--LTWTV--------KECQAIARSENGTNHTIYCRN--------------------WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATN-IWLIILLRFLSGLGT-GKIYQGLCYLTEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLII----TKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIA---SIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNE 1573
NY +A++ + RF V LL S+M + ++VF+ PS+ C P N T+ LT + +E +R + R W Y+K +TI TEF+LVC ++ +T+FFVG+ +G+F + D+ GR ++ + + I F T IW IILL F++GLG L EI + R LY++ + +GYML+P AY +DW+ L L + + +++LPESPRWL G+ +A + + AK+N P N F+ + T+++ N+ D+ +R +L FV T+ Y+ LS N S L ++ +++ FI L+E ++I RR+S++++ + +V L L +S + TL + K++ TT + Y E++PT +RN + I+ S T F S++ +++PY + +V+ IS +FLPE+ PLP+T+E+ +E
Sbjct: 3 NYGDAVAFLGQWGRFQQAVFFLLCASIMP--NGFGAFTLVFMNDIPSHHCRVPESNLTEEWLTSVIPLTEVNGKQELSKCSRYRLDVVRNLSARGFIPHKDINLSDIELEGCVDGWVYSKDIYQSTIVTEFDLVCTEQWKQPFTSTIFFVGVLLGSFFSGPLSDRFGRKPVLFATMAAQTIFTFLSVFTTTWIWFIILL-FINGLGQISNFVAALVLGAEIFTGNVRVLYSSMGTCCGFAVGYMLLPLCAYFLRDWKSLLLALSVPCVAYIPLWWILPESPRWLLSQGRIAEAEAVVKMAAKWNKVQAPSNIFECNSVEKTDTQKEHYNVFDLLRHSRIRTTTLLLCFVLFTLITGYYCLSFNTSQLHTDPYISCFISALVEIPAYASSFIALRYFPRRLSIIVSLIAGAVPLYL---IPLVPEHLSSLSLTLEMVSKYSFTTGASLMFAYTTELYPTVLRNTATGTTTTISRMGSCITPFLLSLSVHYKYLPYVILATLAVVTAISA----YFLPESFKLPLPETIEQMHE 524
BLAST of slc22a-5 vs. Ensembl Medaka
Match: slc22a5 (solute carrier family 22 member 5 [Source:NCBI gene;Acc:101165246]) HSP 1 Score: 132.88 bits (333), Expect = 1.023e-32 Identity = 137/522 (26.25%), Postives = 232/522 (44.44%), Query Frame = 2
Query: 218 IVFIGHTPSYKCVDPIFNQTQ------LTWTVKECQAI----------------------ARSENGTN-HTIYCRN-WKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIA-ICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYL-TEIVSIKRRSLYTN-NYWILYVLGYMLIPGLAYGTKDWR-LSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGN---ITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINF-LICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSI---NGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNE----LRKGNENNYCNMILKHDELYNCKTK 1648
I+F G TP + C+ P N T+ + +T + + I R N T+ C + W Y+K +TI TE+NLVC+ + V ++ FVG G+ I+ D+ GR +++ +++ + + + F+ + + ++ G IY L TE++S R L+T ++ Y +GYM +P +A+G +DWR L L +++ ++ + ESPRWL G+ +A + A+ N P F I + G + DI K +R + + + +I++ YFGLS+N S LS N F+N F+ + E A+I+S+ L R I + + + F V V L GKF T A+ I +Y E++PT +RN+ + + A I ++ AP I D+ +PY + IS ++ FLPET LP+T+E+ E R+ + H+ L + K
Sbjct: 39 IIFAGATPKHHCLIPDVNLTEEWRNAIIPFTEVDGEDIKSQCSRYKLDVVKNLSSEGYVPGRDVNLTSLQQEECLDGWTYSKEIYQSTIVTEWNLVCDNQWKVPFASSSLFVGYLFGSLISGQLSDRFGRKKVVFMSLAVQCLSVLLQSFSQSWKMFCIIFLFVGASQISIYISAFVLGTEVLSKTMRVLFTTLGAFLFYCIGYMTLPWIAFGIRDWRTLLAVLSATSVVYIPLWWFISESPRWLVTQGRVVEAEAIVRDAARRNKVAAPPVIFKESEIQEMPAGRKYTMLDILKFKKLRCITLMCLLLWMSINIGYFGLSLNTSNLSGNPFMNCFLSAISEV----PAYIVSTLLLRVSPRRILLSVFLFLGGGVLLLIQFIPESVQQVALALEMTGKFGFTMAFSIVYIYTAELYPTVLRNVGMGVCSSAARIGSITAPYIIYLGTYDKVLPYILMGSLT----ISSSMVNLFLPETLHKDLPETVEQMQECQGLCRRSKKRKCIQNGATHNSLSQLEAK 552
BLAST of slc22a-5 vs. Planmine SMEST
Match: SMESG000064528.1 (SMESG000064528.1) HSP 1 Score: 992.26 bits (2564), Expect = 0.000e+0 Identity = 515/515 (100.00%), Postives = 515/515 (100.00%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDELYNCKTKL 1651
MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNFPLLFYLTYFLLPESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFNNIIVSIVISTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDELYNCKTKL
Sbjct: 1 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNFPLLFYLTYFLLPESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFYSFNNIIVSIVISTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDELYNCKTKL 515
BLAST of slc22a-5 vs. Planmine SMEST
Match: SMESG000004219.1 (SMESG000004219.1) HSP 1 Score: 186.422 bits (472), Expect = 6.735e-52 Identity = 152/526 (28.90%), Postives = 261/526 (49.62%), Query Frame = 2
Query: 107 MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCV-----DPIFNQTQLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLT--EIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHL-MNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINFLICSVCLMLNNFY---SFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMS---IFIILGIASIFTVFAPSINGIDEFIPYFSCSCY---SVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNY-CNMILKHDEL 1630
M+YE ++I G F+ ++ +TLS+ ++ + F + P + C+ I N T L + +CQ + N C W + K M NT+ E NLVC++ Y L+ T FFVG +I D IG+ L+ +++ II I + IW ++L F+SG+ +Y L Y T EI+ + L N+W LY GYML+ AY + WR L + + + L ++ +PE+PRWL + + +A + IAK N + +F+ +Q G ++ K M + +L F S +Y G + + +F S NIF+ F+ GL+E TGP++ IM++KL R+ S+ + +CL++ F S ++ + L K ++A+ I D+ NE+ PT RN + ++I +G+ SI FAP I+ + + ++ + S++ LI+ +L++ F+PET P+PQT+E+ L E + +MI + ++L
Sbjct: 1 MDYEHLNAKIGGCGLFHYISFMTLSITTFKYVVEFQGLTFALYEPKFSCLVKNISSTIRNSTNLI-SKDQCQYRLSVNDSWNK---CDQWTFEKRFMRNTLINELNLVCDRAFYRELIFTTFFVGCLFSFPFSILSDSIGKRLLLIVSIFLSTIITIGQMVSYQIWQQLVLSFVSGV-CKSVYVSLAYTTLIEIIPVSHIDLAATNFWNLYSFGYMLVALFAYIFRSWRQIYILSLITSIFYVLYFWFVPETPRWLMLNKRRNEAFKTMSFIAKINKCTLNKEEFNKWKPIQQVTGKFWNLLKHKTMIYRFLILNFAGWAFSFAYIGSATDLTFASENIFITTFVMGLIELPTGPLSGIMANKLGRKKSVSALSGLGIICLIIMPFIEADSLKSVWQPWLKVCLAMGAKLGFSSAWLIFDIITNELIPTTDRNTAMSLVYITVGLGSI---FAPMIHSV--LLQFYFAGPFLLYSLLLLITVVLVFAFIPETHHLPVPQTIEQAVSLLIHKEQEWKMDMIQQAEKL 516
BLAST of slc22a-5 vs. Planmine SMEST
Match: SMESG000025822.1 (SMESG000025822.1) HSP 1 Score: 151.369 bits (381), Expect = 2.065e-39 Identity = 140/519 (26.97%), Postives = 253/519 (48.75%), Query Frame = 2
Query: 116 EEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQT--QLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQK-LGNITDIFGSKIMRLKM---FVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRR-VSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASI-------FTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDEL 1630
E+ + + F LA LS+ + S + +I+ +TP Y C ++N + +++ + +C I +G+ TI C W ++ + T+ ++F+LVCN K ++ +++ G + DK GR ++ + E I + F ++ I+ R L G+ Y +L E+V + R + W L YM+ P AY TKDWR+++ + P + Y L PESPRWL + + + I +L IA+ N KI ++ + + K K N K L+M F+L+F +I++ Y +++N LS+N+++++F+ GL+E F G + +S + RR S ++ I S+ ++++ F+S N + ++ G I K A+TT +Y++E+ PT R+ LG ASI FT A IN + + + Y ++ ++ +IY +LPETK P+P+TL + L+ E + + + K E+
Sbjct: 4 EDILKDYNKRNTFKFLAFFILSLPSFQFSSQMQNILISTYTPKYTC---LYNSSFSKISISADQCNMII---DGS--TIVCNKWNFSYEPVGRTMMSDFSLVCNYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEIN-KIDTNINYEQIFVPKTKDEHNTWKALKDKTFSLRMTLSFLLVF---SINLIYAAIAVNLQILSNNMYISMFLLGLME-FPGILFSYVSLRFFRRKTSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRS------LGFASIQLANLCSFTA-AIYINKLSTVLFFLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREM 502
BLAST of slc22a-5 vs. Planmine SMEST
Match: SMESG000025819.1 (SMESG000025819.1) HSP 1 Score: 148.673 bits (374), Expect = 2.293e-38 Identity = 139/519 (26.78%), Postives = 252/519 (48.55%), Query Frame = 2
Query: 116 EEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQT--QLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGRMRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIAKYNGKIFPENKFDSLIITKQK-LGNITDIFGSKIMRLKM---FVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRR-VSMLINFLICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASI-------FTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDEL 1630
E+ + + F LA LS+ + S + +I+ +TP Y C ++N + +++ + +C I +G+ TI C W + + T+ ++F+LVC+ K ++ +++ G + DK GR ++ + E I + F ++ I+ R L G+ Y +L E+V + R + W L YM+ P AY TKDWR+++ + P + Y L PESPRWL + + + I +L IA+ N KI ++ + + K K N K L+M F+L+F +I++ Y +++N LS+N+++++F+ GL+E F G + +S + RR S ++ I S+ ++++ F+S N + ++ G I K A+TT +Y++E+ PT R+ LG ASI FT A IN + + + Y ++ ++ +IY +LPETK P+P+TL + L+ E + + + K E+
Sbjct: 4 EDILKDYNKRNTFKFLAFFILSLPSFQFSSQMQNILISTYTPKYTC---LYNSSFSKISISADQCNMII---DGS--TIVCNKWNFLYEPVGRTMMSDFSLVCDYKNLGDIILIVWYSTSITGPIMGWFSDKFGRKKVAIFNLCLETISTFFVSFTPDVTSNIICRLLIGISANGFYTCYVWLMEMVDNEFREFSGSFIWTYGCLAYMVFPLTAYFTKDWRITQLISLIPNILYFLILLFPESPRWLCVTNRKSELIKSLNKIAEIN-KIDTNINYEQIFVPKTKDEHNTWKALKDKTFSLRMTLSFLLVF---SINLIYAAIAVNLQILSNNMYISMFLLGLME-FPGILFSYVSLRFFRRKTSFILIGGIGSIFILISVFFSRNILWQGVIRIIFGCIAKIAVTTCNQSTMVYVSELCPTSHRS------LGFASIQLANLCSFTA-AIYINKLSTVLFFLPMVIYFILMFLTSCIIYLYLPETKNLPIPETLLDQKMLKVNKEKEFLDYMNKKREM 502
BLAST of slc22a-5 vs. Planmine SMEST
Match: SMESG000025785.1 (SMESG000025785.1) HSP 1 Score: 134.42 bits (337), Expect = 1.717e-33 Identity = 132/520 (25.38%), Postives = 245/520 (47.12%), Query Frame = 2
Query: 116 EEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVDPIFNQT--QLTWTVKECQAIARSENGTNHTIYCRNWKYNKTDMTNTISTEFNLVCNKKKYVTLMNTMFFVGMSVGNFIAICGDKIGR--MRLIHLAVIWEIIINICLPFATNIWLIILLRFLSGLGTGKIYQGLCYLTEIVSIKRRSLYTNNYWILYVLGYMLIPGLAYGTKDWRLSRHLMNXXXXXXXXXXXXXESPRWLGIGGKFKKAITNLLLIA---KYNGKIFPEN-KFDSLIITKQKLGNITDIFGSKIMRLKMFVLIFVHGTISVSYFGLSINESFLSSNIFLNVFIQGLLETFTGPVAWIMSSKLNRRVSMLINF-LICSVCLMLNNFYSFXXXXXXXXXXTLGSIGKFALTTAYCICDMYLNEVFPTPIRNMSIFIILGIASIFTVFAPSINGIDEFIPYFSCSCYSVMCLISGLLIYFFLPETKGCPLPQTLEEGNELRKGNENNYCNMILKHDELYNCKTK 1648
E IS + F V+A L LS+ A +++ TP++ C +N+T Q+ + +C + NG+N + C++W ++ TI ++++LVC+ K L+ +++ + DK GR + +I L++ E + L F N++ I R G + +L E+V+ R++ + +W+ + + P Y T++WRL++ + P + Y+ +PESPRWL + K ++ + +L IA K + ++ PE K + K D+ + +F + + IS L++ LSSNI++++F+ GL+E F G + +S +R M+ F + S+ + L+ S + SI GSIGK + T+ +Y E+FPT R++ ++ I + A IN +++F + Y ++ +IS LI+ F+PETKG P+P+T+ + L K E Y + ++ N +
Sbjct: 4 ENVISFYNKKDTFKVIAFLILSLPAFQYGSQFQNLLVSIRTPNFTCQ---YNETSHQIQISKDQC---TMTINGSN--VKCQHWTFSSEPFGETIMSDYDLVCDYKYVGDLLVLLWYSTSLMAPVFGWLADKYGRKMISIIFLSI--ETVATFILAFTPNLYSHIFFRLCIGFSESAYHICYVWLMEMVNKDFRNVAGSFFWLYGSVAMTVFPLTVYVTRNWRLTQLISLTPSILYVLILFVPESPRWLCVKNKKQQLMESLQTIANINKMDLQLTPEEIKIEKTTKEWNKWNAFKDMNFLFLASTSLFAVFSISILISAILIDLNL----LSSNIYISMFVLGLME-FPGALLSYLSMYFFKRKRMITIFSMFGSIFIFLSVTLSKVDKWQSIFRMIFGSIGKVLVMTSSQGVLVYATELFPTTHRSLFFGMLQIILLMAMTAAVYINKLNQFYGFIPMLIYFLLNMISCCLIFVFMPETKGLPIPETIFDQRLLVKEREQEYLEYMYNRSDVVNSDRE 508 The following BLAST results are available for this feature:
BLAST of slc22a-5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slc22a-5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of slc22a-5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of slc22a-5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slc22a-5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slc22a-5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slc22a-5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slc22a-5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc22a-5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slc22a-5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of slc22a-5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of slc22a-5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of slc22a-5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slc22a-5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024134 ID=SMED30024134|Name=slc22a-5|organism=Schmidtea mediterranea sexual|type=transcript|length=1698bpback to top protein sequence of SMED30024134-orf-1 >SMED30024134-orf-1 ID=SMED30024134-orf-1|Name=SMED30024134-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=516bp MNYEEAISEIQGNERFNVLALLTLSMMACISSMDINSIVFIGHTPSYKCVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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