otopetrin-2

Overview
Nameotopetrin-2
Smed IDSMED30024125
Length (bp)3068
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of otopetrin-2 (SMED30024125) t-SNE clustered cells

Violin plots show distribution of expression levels for otopetrin-2 (SMED30024125) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of otopetrin-2 (SMED30024125) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for otopetrin-2 (SMED30024125) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30024125

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
muscle cellSMED30024125SMESG000031517.1 dd_Smed_v4_15458_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
body wall musculatureSMED30024125SMESG000031517.1 dd_Smed_v4_15458_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of otopetrin-2 vs. Ensembl Celegans
Match: otpl-8 (OToPetrin-Like [Source:UniProtKB/TrEMBL;Acc:G5EDX5])

HSP 1 Score: 120.553 bits (301), Expect = 7.161e-28
Identity = 146/615 (23.74%), Postives = 269/615 (43.74%), Query Frame = 1 
Query: 1153 NYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGL-LFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILK---IQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANI---VVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 2976
            N+   +I+++YA++L  IS+V+ V   T     + A   FYI +Y VGI+F  Y Y +++        + GP  ++ +  L     + N+++   +                                   S+H+ +  G L LRL  L  G V ++  GL LF  + + +         C+   +A + + ++++TFIQ++FIF NSKI  +  + I   G+MH+I+VNL   F+ V+     +Q     +   L +       +      E +++L        L       T+ P  +    L H GD+          ++  C V+Y LI AA++++ W+               SI +++       KR +    +CS S  G+F G++ +I ++V + ++ I     N     L      +++L   A  A ++  ++M+ L  Q R H+    + ++E LL+I ++ G  L+    I   +  R  ++   S       ++ ++Q  +Q+ F+ T  R         + KPG+E++ FLL++N  L+  H FE  K  + F    K   Q+ +  I +   PL++ +R  S   LA IWK  Y  +S+
Sbjct:   62 NFFVRLITSLYALILTIISLVVEV-SPTWRTDMWLAETIFYISMYGVGILFFAYCYIFII--------YPGPY-NQLISVLRKYKIIKNSEVWFIM----------------------------------QSQHNGEGAGTLYLRLGALFFGSVGIVLFGLELFLCIENVA---------CKKVAIA-KMIVAIVFTFIQMHFIFCNSKITVNSSRKIVAFGMMHLISVNLWTWFRFVLA----KQEAKAHKKAQLKQTFRKYYSSSSSSSSEEIHELISAVLNSTLNNTPATKTMEPVASRLFALEHFGDV--------ATFLTTCIVEYSLIGAAIMFILWK---------------SIGQNNHQQSNSGKRKVKMRIDCSSSSTGLFAGIIFLIGSLVSMGMYTIFESLRNSSGAQLVFGI-VDLSLFSIALGACIIGLWRMRHL--QYRLHAH--GEVIDEILLIIGLI-GEILYCAVGIDVFITCRRSADLTVSALPAFVFVIRMIQVVVQAAFILTTSRLRCLSKYSMKYKPGKEIITFLLVSNVTLFVFHTFEGMK--SSFGFSSKAATQYNY--IIYAVGPLLVFYRFHSSACLAEIWKHTYSTKSN 585
[Close]
BLAST of otopetrin-2 vs. Ensembl Celegans
Match: otpl-1 (OToPetrin-Like [Source:UniProtKB/TrEMBL;Acc:O45067])

HSP 1 Score: 111.309 bits (277), Expect = 7.465e-25
Identity = 113/469 (24.09%), Postives = 214/469 (45.63%), Query Frame = 1 
Query: 1570 GGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVI-KDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGG-DLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDL-LFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPS--PFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAY 2961
            G L LRL  +  GV  ++    L   V      PN S     S+ + V C  ++++ FIQ++FIF N K+      ++AR+G MH++A NL    + V+ ++ + E+ I   E+ N HRP     P   +++             +   +      ++++ K +  G    ++ ++ +    ++   V+Y LI AA++++ WRNI               ++   +++ +RK  I    +CS +  G+F+GL  +      +VV++        +  A   +++     ++S T+  + A ++M+ L  F  +   +   Q L + +LL   + G  ++SVA +V   L  EK  +   F+L+   +  L       F+    R V     H   +PG++ + FLL AN A++ ++LFE  K   V  +  + +G+ +W  +     PL + +R  S +  A IWK  Y
Sbjct:  180 GSLFLRLGSVVFGVTGVVYYAFL---VFLCELDPNCSAL---STSLDV-C--AILFIFIQMHFIFCNWKLSITGSHMVARVGTMHLVAANLWTWIRYVLMEEGVMEKEI--REVFN-HRP-----PGHNYMRSNSSDSSSSAENSMEQFLGDGSHEDEHFEKKIMPGSCQAVECILGSMSEIMFTSIVEYSLIAAAVMYIVWRNIG--------------RQDQGSTYVKRKHQI--RVDCSKTTTGLFLGLAFLAVTFTSMVVYYGFTMMNKSQSAAFVYAFTDMFQYVLS-TIGVLTAIYQMRALKYFNKKTKLQNSDQELLDQILLSIGLVGELIYSVAGLV--GLTGEKQWTNFSFILLFVHIFRLIQVGTQTFLLHVARSVRMGCEHREAQPGKQAITFLLTANLAIFFMNLFESEK-AGVSEMIIEYYGKRSWVFLVRSFSPLTIFYRFHSSVCFAEIWKNVY 611
[Close]
BLAST of otopetrin-2 vs. Ensembl Celegans
Match: otpl-1 (OToPetrin-Like [Source:UniProtKB/TrEMBL;Acc:O45067])

HSP 1 Score: 110.923 bits (276), Expect = 8.717e-25
Identity = 114/475 (24.00%), Postives = 215/475 (45.26%), Query Frame = 1 
Query: 1552 HHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVI-KDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGG-DLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDL-LFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPS--PFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAY 2961
            H     G L LRL  +  GV  ++    L   V      PN S     S+ + V C  ++++ FIQ++FIF N K+      ++AR+G MH++A NL    + V+ ++ + E+ I   E+ N HRP     P   +++             +   +      ++++ K +  G    ++ ++ +    ++   V+Y LI AA++++ WRNI               ++   +++ +RK  I    +CS +  G+F+GL  +      +VV++        +  A   +++     ++S T+  + A ++M+ L  F  +   +   Q L + +LL   + G  ++SVA +V   L  EK  +   F+L+   +  L       F+    R V     H   +PG++ + FLL AN A++ ++LFE  K   V  +  + +G+ +W  +     PL + +R  S +  A IWK  Y
Sbjct:  158 HSSPSAGSLFLRLGSVVFGVTGVVYYAFL---VFLCELDPNCSAL---STSLDV-C--AILFIFIQMHFIFCNWKLSITGSHMVARVGTMHLVAANLWTWIRYVLMEEGVMEKEI--REVFN-HRP-----PGHNYMRSNSSDSSSSAENSMEQFLGDGSHEDEHFEKKIMPGSCQAVECILGSMSEIMFTSIVEYSLIAAAVMYIVWRNIG--------------RQDQGSTYVKRKHQI--RVDCSKTTTGLFLGLAFLAVTFTSMVVYYGFTMMNKSQSAAFVYAFTDMFQYVLS-TIGVLTAIYQMRALKYFNKKTKLQNSDQELLDQILLSIGLVGELIYSVAGLV--GLTGEKQWTNFSFILLFVHIFRLIQVGTQTFLLHVARSVRMGCEHREAQPGKQAITFLLTANLAIFFMNLFESEK-AGVSEMIIEYYGKRSWVFLVRSFSPLTIFYRFHSSVCFAEIWKNVY 595
[Close]
BLAST of otopetrin-2 vs. Ensembl Celegans
Match: otpl-1 (OToPetrin-Like [Source:UniProtKB/TrEMBL;Acc:O45067])

HSP 1 Score: 110.923 bits (276), Expect = 1.570e-24
Identity = 114/475 (24.00%), Postives = 215/475 (45.26%), Query Frame = 1 
Query: 1552 HHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVI-KDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGG-DLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDL-LFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPS--PFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAY 2961
            H     G L LRL  +  GV  ++    L   V      PN S     S+ + V C  ++++ FIQ++FIF N K+      ++AR+G MH++A NL    + V+ ++ + E+ I   E+ N HRP     P   +++             +   +      ++++ K +  G    ++ ++ +    ++   V+Y LI AA++++ WRNI               ++   +++ +RK  I    +CS +  G+F+GL  +      +VV++        +  A   +++     ++S T+  + A ++M+ L  F  +   +   Q L + +LL   + G  ++SVA +V   L  EK  +   F+L+   +  L       F+    R V     H   +PG++ + FLL AN A++ ++LFE  K   V  +  + +G+ +W  +     PL + +R  S +  A IWK  Y
Sbjct:  295 HSSPSAGSLFLRLGSVVFGVTGVVYYAFL---VFLCELDPNCSAL---STSLDV-C--AILFIFIQMHFIFCNWKLSITGSHMVARVGTMHLVAANLWTWIRYVLMEEGVMEKEI--REVFN-HRP-----PGHNYMRSNSSDSSSSAENSMEQFLGDGSHEDEHFEKKIMPGSCQAVECILGSMSEIMFTSIVEYSLIAAAVMYIVWRNIG--------------RQDQGSTYVKRKHQI--RVDCSKTTTGLFLGLAFLAVTFTSMVVYYGFTMMNKSQSAAFVYAFTDMFQYVLS-TIGVLTAIYQMRALKYFNKKTKLQNSDQELLDQILLSIGLVGELIYSVAGLV--GLTGEKQWTNFSFILLFVHIFRLIQVGTQTFLLHVARSVRMGCEHREAQPGKQAITFLLTANLAIFFMNLFESEK-AGVSEMIIEYYGKRSWVFLVRSFSPLTIFYRFHSSVCFAEIWKNVY 732
[Close]
BLAST of otopetrin-2 vs. Ensembl Celegans
Match: otpl-5 (OToPetrin-Like [Source:UniProtKB/TrEMBL;Acc:G4SFC1])

HSP 1 Score: 108.612 bits (270), Expect = 3.374e-24
Identity = 108/428 (25.23%), Postives = 199/428 (46.50%), Query Frame = 1 
Query: 1693 RSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNL-SGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGV-IQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVA--NIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQ 2964
            R     V+ + ++I+TF+Q++FIF NSKI   +  +IA+ GLMH +AVNL + L   +IK SI                        +  K+E  Y  +    E   +I T +S +        H   L   + + +S   +  C V++ LI A + ++ W+N ++ S            E+ +   +R  R      +CSG+  GIF+ +   I + V + +  IL +        L + Y+ ++ L + A +A +LA F+M+ L ++   H   I +     +LLI  +AG  ++S A  ++ +     ++P S   ++   L + +  +Q+IF+    R   Y   +   +PG++++ FLL+ N  L+  H FE  +L+  F +        +++ + +I  P+++ +R  S   LA IWK  Y 
Sbjct:  174 RHGIYVVKYILAVIFTFMQMHFIFSNSKISLKRSNIIAKFGLMHSVAVNLWNWLSICLIKSSI------------------------KHAKKEIKYTYEGSDNETKTEILTEMSYDFTTDSFGPHDKQLRAIIKLGSSSSILLTCLVEFSLIAAVICFIIWKNDDSNS-----------GEALKKKKKRHFRF-----DCSGTTVGIFLAVAVHIISAVAVGMHGILSKSNRDSAANLLVGYT-DVFLFVVALLACILAFFQMRKLQYRLHAHGEVIDE-----ILLIVGLAGECVYSCAGMDLYINDKMIKEPASYITIVSFTLRITEVLVQTIFILIATRMRCYTQTNCYTEPGKQVITFLLVCNINLFIYHTFETTELNFGFPIKLPD----SYSAMLNIASPIVVFYRFHSSACLAEIWKHTYS 551
[Close]
BLAST of otopetrin-2 vs. Ensembl Fly
Match: OtopLc (gene:FBgn0259150 transcript:FBtr0331168)

HSP 1 Score: 222.246 bits (565), Expect = 5.305e-59
Identity = 153/615 (24.88%), Postives = 317/615 (51.54%), Query Frame = 1 
Query: 1153 NYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHE-MDMKRFSL--DYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINS-KICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMS-TLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIE--TTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 2976
            + L T+ SA+Y  LL+ + +  P+ E+ + +   + YE +Y++LY+  ++FL+++Y  L+  +                     + + +   SAT A  TD   +   + N +   +   + ++R SL       + HY   G   LR+  +  G+ SMI  GL FG+  + +  P++    C +  +A+     + + FIQ+YFIF+N+ +I  +++++IAR GLMHMI  NL+     +I+++       + EI+  + P + TL  + R       + +    P   L++   +  +  +    C   +++  ++Q + P+++PCT++Y LI AA+L++ WR+I    T T   P++  S  + S   +         + +C+ + KG+FVG++ ++  I+ L++F +L+ +P     A+      E+ +  +AT+AT++   +++ L +   + S  +     + +LL+    G +L+++  ++ G  ++ +     + I ++ S++Q + Q++F+    RR +    H R KPGRE+V F+L+ N A+W +   E+ + ++   +    +G W W +I+H+++PL + +R  S + L  IWK+AY+ + +
Sbjct:  890 DALATLFSALYGKLLVVMGIAFPMAEVISTYIPPSFYEVYYLYLYIGSMIFLLFMYATLIWGRP-----------------KLPVPIASPSKSATKASGTDSMDESDTDSNSVHHRLPPPIPVRRPSLLSPLGRRDAHY---GSFYLRMGAVAFGIGSMIYSGLEFGQYFELN--PDTK---CHNVLLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKIIARFGLMHMIGTNLAVWLNVLIQET-------KHEILTFYNPENRTLRISHRIPGHSRGHAIIQHDPTAHLRVPRGL--KGPYQIFECRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSISRPQTPTPQRPDMISSPMKRSPHHY---------SVDCARAHKGLFVGILILVLTIISLIIFFVLISRPEFVAMAVTEVTICELLIYGTATIATLVGMIQIRHLQYD-AYRSFSL-----DDILLVGAQTGSFLYNIFTVIAGH-FTLRSDDMLVPINALASIVQTACQTMFILDASRRQAVSPEHLRKKPGREIVTFMLVVNLAMWAISTLEKSRAES-HPIQLNFYGLWAWTIITHVSMPLAIFYRFHSTVCLCEIWKRAYKLKPT 1453
[Close]
BLAST of otopetrin-2 vs. Ensembl Fly
Match: OtopLc (gene:FBgn0259150 transcript:FBtr0346834)

HSP 1 Score: 222.631 bits (566), Expect = 5.538e-59
Identity = 153/615 (24.88%), Postives = 317/615 (51.54%), Query Frame = 1 
Query: 1153 NYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHE-MDMKRFSL--DYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINS-KICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMS-TLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIE--TTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 2976
            + L T+ SA+Y  LL+ + +  P+ E+ + +   + YE +Y++LY+  ++FL+++Y  L+  +                     + + +   SAT A  TD   +   + N +   +   + ++R SL       + HY   G   LR+  +  G+ SMI  GL FG+  + +  P++    C +  +A+     + + FIQ+YFIF+N+ +I  +++++IAR GLMHMI  NL+     +I+++       + EI+  + P + TL  + R       + +    P   L++   +  +  +    C   +++  ++Q + P+++PCT++Y LI AA+L++ WR+I    T T   P++  S  + S   +         + +C+ + KG+FVG++ ++  I+ L++F +L+ +P     A+      E+ +  +AT+AT++   +++ L +   + S  +     + +LL+    G +L+++  ++ G  ++ +     + I ++ S++Q + Q++F+    RR +    H R KPGRE+V F+L+ N A+W +   E+ + ++   +    +G W W +I+H+++PL + +R  S + L  IWK+AY+ + +
Sbjct:  890 DALATLFSALYGKLLVVMGIAFPMAEVISTYIPPSFYEVYYLYLYIGSMIFLLFMYATLIWGRP-----------------KLPVPIASPSKSATKASGTDSMDESDTDSNSVHHRLPPPIPVRRPSLLSPLGRRDAHY---GSFYLRMGAVAFGIGSMIYSGLEFGQYFELN--PDTK---CHNVLLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKIIARFGLMHMIGTNLAVWLNVLIQET-------KHEILTFYNPENRTLRISHRIPGHSRGHAIIQHDPTAHLRVPRGL--KGPYQIFECRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSISRPQTPTPQRPDMISSPMKRSPHHY---------SVDCARAHKGLFVGILILVLTIISLIIFFVLISRPEFVAMAVTEVTICELLIYGTATIATLVGMIQIRHLQYD-AYRSFSL-----DDILLVGAQTGSFLYNIFTVIAGH-FTLRSDDMLVPINALASIVQTACQTMFILDASRRQAVSPEHLRKKPGREIVTFMLVVNLAMWAISTLEKSRAES-HPIQLNFYGLWAWTIITHVSMPLAIFYRFHSTVCLCEIWKRAYKLKPT 1453
[Close]
BLAST of otopetrin-2 vs. Ensembl Fly
Match: OtopLc (gene:FBgn0259150 transcript:FBtr0331167)

HSP 1 Score: 222.246 bits (565), Expect = 6.292e-59
Identity = 153/615 (24.88%), Postives = 317/615 (51.54%), Query Frame = 1 
Query: 1153 NYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHE-MDMKRFSL--DYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINS-KICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMS-TLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIE--TTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 2976
            + L T+ SA+Y  LL+ + +  P+ E+ + +   + YE +Y++LY+  ++FL+++Y  L+  +                     + + +   SAT A  TD   +   + N +   +   + ++R SL       + HY   G   LR+  +  G+ SMI  GL FG+  + +  P++    C +  +A+     + + FIQ+YFIF+N+ +I  +++++IAR GLMHMI  NL+     +I+++       + EI+  + P + TL  + R       + +    P   L++   +  +  +    C   +++  ++Q + P+++PCT++Y LI AA+L++ WR+I    T T   P++  S  + S   +         + +C+ + KG+FVG++ ++  I+ L++F +L+ +P     A+      E+ +  +AT+AT++   +++ L +   + S  +     + +LL+    G +L+++  ++ G  ++ +     + I ++ S++Q + Q++F+    RR +    H R KPGRE+V F+L+ N A+W +   E+ + ++   +    +G W W +I+H+++PL + +R  S + L  IWK+AY+ + +
Sbjct:  890 DALATLFSALYGKLLVVMGIAFPMAEVISTYIPPSFYEVYYLYLYIGSMIFLLFMYATLIWGRP-----------------KLPVPIASPSKSATKASGTDSMDESDTDSNSVHHRLPPPIPVRRPSLLSPLGRRDAHY---GSFYLRMGAVAFGIGSMIYSGLEFGQYFELN--PDT---KCHNVLLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKIIARFGLMHMIGTNLAVWLNVLIQET-------KHEILTFYNPENRTLRISHRIPGHSRGHAIIQHDPTAHLRVPRGL--KGPYQIFECRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSISRPQTPTPQRPDMISSPMKRSPHHY---------SVDCARAHKGLFVGILILVLTIISLIIFFVLISRPEFVAMAVTEVTICELLIYGTATIATLVGMIQIRHLQYD-AYRSFSL-----DDILLVGAQTGSFLYNIFTVIAGH-FTLRSDDMLVPINALASIVQTACQTMFILDASRRQAVSPEHLRKKPGREIVTFMLVVNLAMWAISTLEKSRAES-HPIQLNFYGLWAWTIITHVSMPLAIFYRFHSTVCLCEIWKRAYKLKPT 1453
[Close]
BLAST of otopetrin-2 vs. Ensembl Fly
Match: OtopLb (gene:FBgn0031514 transcript:FBtr0077609)

HSP 1 Score: 179.874 bits (455), Expect = 2.649e-46
Identity = 150/622 (24.12%), Postives = 287/622 (46.14%), Query Frame = 1 
Query: 1171 ISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINS---KICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQ-NIGQTEIINLHRPM---STLSPTQRFLKQEGLY----------KLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXX---XXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHH-KVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFES 2973
            +SA Y  LL+ + V LP+ E+ +       Y+GFY++LYV  I+F++++Y    R++++                               AL+         + ++  + VH              +H    +G   LR+  +   + +M+  GL FG+  + +  P      CR   VA+  +  ++    Q+ FIF+N+    +  HK  V +R GLMHM+A NL      +++++  E  +I Q E+   H  +   S++S T      E L+           L      +I+ +  T SP        C    +M  ++Q   P+++PCT++Y LI A +L+  W+ +++      P++  + + S + +  +       + +CS S KG+F G++ ++  I+ ++++ +L  +P   L A +    +E  +      A +     M+DL +         +  L+  LL+++   GVYL+ + +I+ G  +++    P  +      +  ++Q S+Q++F+     R    T   R KPGRE++ FLL+AN A+W ++   + +   VF   H + FG W W +I+HI++PL + +R  S I L  +WK  Y+ ++
Sbjct:  245 LSATYCKLLVLLGVCLPITEVISDQIPTYVYQGFYVYLYVGSILFVIFLYISAFRNRSLFN-----------------------------ALK---------DYHEKNSNVHL-------------KHKVTHFGSFYLRVGAIAFAIGTMVYSGLEFGQFFELNGHPG-----CRDVFVAITPICRMVLCIAQVQFIFLNTTYMDMARHK--VTSRFGLMHMVATNLCEWLYVLVEETKHEIFHISQHEVDPAHDLVIHNSSMSRTDWAAVNESLHQHHHHHALNNTLVANVSSVIVNMTITPSPTPAAFSG-CSRTTIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKSI-----PDIDKTRKNSVKPAAAKPAHHF--SVDCSQSHKGLFFGILIIVMTIISMIMYFVLYTQPGYELVATQEVTLWETFMYFMCAAAVITGMILMRDLRYIKNTSDEHHSMDLDNLLLIVAQT-GVYLYGMFSIL-GSYFAKWDTVPDRVEGIIAEVFGVVQTSLQTMFILHSSHRRCRGTNQVRRKPGREIITFLLVANIAIWFVNTLIKGRA--VFRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWKITYKAKA 796
[Close]
BLAST of otopetrin-2 vs. Ensembl Fly
Match: OtopLb (gene:FBgn0031514 transcript:FBtr0344796)

HSP 1 Score: 177.948 bits (450), Expect = 2.668e-46
Identity = 150/619 (24.23%), Postives = 285/619 (46.04%), Query Frame = 1 
Query: 1171 ISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINS---KICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQ-NIGQTEIINLHRPM---STLSPTQRFLKQEGLY----------KLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXX---XXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHH-KVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQ 2964
            +SA Y  LL+ + V LP+ E+ +       Y+GFY++LYV  I+F++++Y    R++++                               AL+         + ++  + VH              +H    +G   LR+  +   + +M+  GL FG+  + +  P      CR   VA+  +  ++    Q+ FIF+N+    +  HK  V +R GLMHM+A NL      +++++  E  +I Q E+   H  +   S++S T      E L+           L      +I+ +  T SP        C    +M  ++Q   P+++PCT++Y LI A +L+  W+ +++      P++  + + S + +  +       + +CS S KG+F G++ ++  I+ ++++ +L  +P   L A +    +E  +      A +     M+DL +         +  L+  LL+++   GVYL+ + +I+ G  +++    P  +      +  ++Q S+Q++F+     R    T   R KPGRE++ FLL+AN A+W ++   + +   VF   H + FG W W +I+HI++PL + +R  S I L  +WK  Y+
Sbjct:   95 LSATYCKLLVLLGVCLPITEVISDQIPTYVYQGFYVYLYVGSILFVIFLYISAFRNRSLFN-----------------------------ALK---------DYHEKNSNVHL-------------KHKVTHFGSFYLRVGAIAFAIGTMVYSGLEFGQFFELNGHPG-----CRDVFVAITPICRMVLCIAQVQFIFLNTTYMDMARHK--VTSRFGLMHMVATNLCEWLYVLVEETKHEIFHISQHEVDPAHDLVIHNSSMSRTDWAAVNESLHQHHHHHALNNTLVANVSSVIVNMTITPSPTPAAFSG-CSRTTIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKSI-----PDIDKTRKNSVKPAAAKPAHHF--SVDCSQSHKGLFFGILIIVMTIISMIMYFVLYTQPGYELVATQEVTLWETFMYFMCAAAVITGMILMRDLRYIKNTSDEHHSMDLDNLLLIVAQ-TGVYLYGMFSIL-GSYFAKWDTVPDRVEGIIAEVFGVVQTSLQTMFILHSSHRRCRGTNQVRRKPGREIITFLLVANIAIWFVNTLIKGRA--VFRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWKITYK 643
[Close]
BLAST of otopetrin-2 vs. UniProt/SwissProt
Match: sp|B7Z0W9|OTOP_DROME (Proton channel OtopLc OS=Drosophila melanogaster OX=7227 GN=OtopLc PE=3 SV=2)

HSP 1 Score: 222.246 bits (565), Expect = 6.307e-58
Identity = 153/615 (24.88%), Postives = 317/615 (51.54%), Query Frame = 1 
Query: 1153 NYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHE-MDMKRFSL--DYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINS-KICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMS-TLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIE--TTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 2976
            + L T+ SA+Y  LL+ + +  P+ E+ + +   + YE +Y++LY+  ++FL+++Y  L+  +                     + + +   SAT A  TD   +   + N +   +   + ++R SL       + HY   G   LR+  +  G+ SMI  GL FG+  + +  P++    C +  +A+     + + FIQ+YFIF+N+ +I  +++++IAR GLMHMI  NL+     +I+++       + EI+  + P + TL  + R       + +    P   L++   +  +  +    C   +++  ++Q + P+++PCT++Y LI AA+L++ WR+I    T T   P++  S  + S   +         + +C+ + KG+FVG++ ++  I+ L++F +L+ +P     A+      E+ +  +AT+AT++   +++ L +   + S  +     + +LL+    G +L+++  ++ G  ++ +     + I ++ S++Q + Q++F+    RR +    H R KPGRE+V F+L+ N A+W +   E+ + ++   +    +G W W +I+H+++PL + +R  S + L  IWK+AY+ + +
Sbjct:  890 DALATLFSALYGKLLVVMGIAFPMAEVISTYIPPSFYEVYYLYLYIGSMIFLLFMYATLIWGRP-----------------KLPVPIASPSKSATKASGTDSMDESDTDSNSVHHRLPPPIPVRRPSLLSPLGRRDAHY---GSFYLRMGAVAFGIGSMIYSGLEFGQYFELN--PDT---KCHNVLLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKIIARFGLMHMIGTNLAVWLNVLIQET-------KHEILTFYNPENRTLRISHRIPGHSRGHAIIQHDPTAHLRVPRGL--KGPYQIFECRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSISRPQTPTPQRPDMISSPMKRSPHHY---------SVDCARAHKGLFVGILILVLTIISLIIFFVLISRPEFVAMAVTEVTICELLIYGTATIATLVGMIQIRHLQYD-AYRSFSL-----DDILLVGAQTGSFLYNIFTVIAGH-FTLRSDDMLVPINALASIVQTACQTMFILDASRRQAVSPEHLRKKPGREIVTFMLVVNLAMWAISTLEKSRAES-HPIQLNFYGLWAWTIITHVSMPLAIFYRFHSTVCLCEIWKRAYKLKPT 1453
[Close]
BLAST of otopetrin-2 vs. TrEMBL
Match: A0A1S3HXZ4 (otopetrin-2 OS=Lingula unguis OX=7574 GN=LOC106159232 PE=4 SV=1)

HSP 1 Score: 324.324 bits (830), Expect = 4.168e-93
Identity = 232/708 (32.77%), Postives = 362/708 (51.13%), Query Frame = 1 
Query:  886 ADSGISNTSPETQSSTEFYQRKLHDTIISGKVSHSSSGRFSVPSIGITGTGMGPKLHHTPRLPSGQYPQSILKFSKDHFSLIQITADFKNYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFE-----QNIGQTEIINL-HRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTS---TRFDPNVTGSIQESSRASFQR----RKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFE 2970
             DSGI N SPETQS+ E Y             SH+     +  S+G         L +   L +G           D  +L  +   F++ LF I+S +Y++ ++ +  VLP+ EI       N +E FYI+LY V I+FL+Y+Y +LL++ T                                   ++    R  + N   T + E   ++ S+D   S H     G   LRL  +G G+ +M+ DGL FG   +   S   SP  C +  +AVR +  L++TF+QLYFIF+NSK+C HK++V+AR GLMHM A N+    + ++K+++ E      N   TE ++L H     L      LKQ      + P+  I   + T   P    T L C   D+M  V+  + PY+YPC VQY LI +A+L+  WRNI   +   + F   +  +    ++   QR     +R I+   +C GS KG+FVG++ ++  I+ ++ F +LV+KP+ +  A+ + ++ EI L +   V  + A F++QDL F  +   + I   L+ETLLLIS+  GVY+ S+ +IV G   +       +++   L LL++S+ +IFV  GLRR SYK  HE  KPGRELV FLL+ N A+W +++F+ R+ + V  +    +G   W +ISHI+ PL + FR  + + LA IW+ AY+ +
Sbjct:  179 GDSGIGNGSPETQSTVEHYP------------SHTEIRPATPGSMG--------SLEYRAGLCNG-----------DVQALRNMQEAFRSSLFNILSGLYSIFVIILGAVLPIAEIFAQPVAINFFEAFYIYLYGVSIIFLIYVYAFLLQNAT-----------------------------------SEYTRKRAQQANNAHTAILEKS-RKVSIDSSGSHHT----GSFYLRLGAVGFGIGNMLLDGLRFGEFFEMDLS---SP--CSNILLAVRPMVHLVFTFVQLYFIFLNSKMCIHKYKVLARFGLMHMFATNICVWLRNLMKETLRELQHKAVNTSLTEYLSLQHFTPVHLRDAAGVLKQGA---AEAPNYNISTNMTTRNPPI--LTLLDCQRRDIMGNVVDQAAPYLYPCAVQYSLIGSAILYTIWRNIGKRTSPLSTFYSTIQNNWSPKNKVQTQRPVCDNQRQIV---DCQGSTKGLFVGILLLVVTIISMIAFFVLVEKPSYQSIAVIVVHAAEITLHLITAVTVLAAFFRVQDLYFNIK---KDIG--LDETLLLISL-TGVYIFSIFSIVAGYYNTTTYGGTLIVVTGTLQLLESSLLTIFVLNGLRRRSYKPSHEESKPGRELVTFLLVCNIAMWGVNIFQTRRAE-VNPVQTDFYGNLLWVIISHISTPLNIFFRFHAAVCLANIWRNAYKVK 795
[Close]
BLAST of otopetrin-2 vs. TrEMBL
Match: A0A267EC74 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig019121g1 PE=4 SV=1)

HSP 1 Score: 321.627 bits (823), Expect = 6.843e-91
Identity = 244/766 (31.85%), Postives = 365/766 (47.65%), Query Frame = 1 
Query:  823 NRVDCSLSRGAAESIGLHSQA-ADSGISNTSPETQSSTEFYQRKLHDTIISGKVSHSSSGRFSVPSIGITGTGMGPKLHHTPRLPSGQY---PQSILKFSKD---HFSLIQITADFKNYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNI-ETTSTRFD-------PNVT--------------------------GSIQES-------SRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 2976
             R++ +L+   AESI L   A ADSGISNTSPETQSSTEF    +                    SI    + M P L              P  ILK  +D     +++Q  A FK  LF ++S +Y MLL  + +++P  E+       + +EGFYI+LY V ++FL+Y+Y +L+R++   R       S       + +  D A   +   L     G           G H    +RF +    S       G   LRL  +G G+VSMIRDGL     + T+    S  A C    +AVR +  +I+TF+QL F+F+N+K+C HK++ +AR GL H+IA NL    +TV K+S+        EI+          P +      G           I       S   +  +     G+++ G++  SDPY++P TVQY L+ AA+LW++WRN+    S RFD       P+ T                          GS++ +       + +   RR        +C+GS +G+F+GL  ++   V L+   +L+Q+P         SY  E+AL+ +     + A  +M D+L+      R   +RL+E L L ++ AG   H +  ++ G      PP P +   S   LLQAS+Q+ FVCT L+R+SYK +HER+KPGRELV FLL+ N AL+     E  +L          FG+  +AV  H+T PL  +FR  S++ALA +WK+AYQF+S+
Sbjct:  258 GRIETTLAENIAESIALQCAAVADSGISNTSPETQSSTEFQTNAMR-------------------SIETLASPMQPILAQNLLHLQHHQHLHPTGILKPGRDLAEQHNIMQ--AAFKASLFRLLSGIYVMLLCALGLLMPTAELLAKKVALHLFEGFYIYLYSVSLLFLIYVYAFLVREEAGRR-------SACGGGGGSGVGGDMAGDGSVAFL-----GGHSTARPSGGGGSHR---RRFLVRASLS----GGAGSFYLRLGAIGFGIVSMIRDGL----TVATAVQHGSRLAECSGLALAVRPILGIIFTFVQLNFLFLNAKMCIHKYKALARFGLAHLIATNLCVWLRTVAKESV-------AEIL--------AEPAKNSTSDSG----------SIGTAGGAASANVSSHRCASETGEVLKGLVARSDPYLFPTTVQYSLLAAAILWMTWRNVGRPGSRRFDSASLDSSPDGTLTSPAHQQQSQQQPPAPQSPPQARPSGSVEAADPVADTAASSRCHRRHGGSGGGLDCAGSHRGLFLGLAALVGGAVALLASGVLMQQPQYYSAGSLASYCGELALLAAGLATALAAFPRMADMLY---VSGR--DRRLDEALQLATL-AGSLAHWLLPLMAG-----PPPGPHVAACSAAQLLQASVQAAFVCTALKRMSYKALHEREKPGRELVTFLLVCNVALFAFAATEPLRLAEARL--GPAFGRVAFAVADHLTRPLHCLFRFHSVVALATVWKEAYQFKSA 941
[Close]
BLAST of otopetrin-2 vs. TrEMBL
Match: A0A1S3KEJ4 (otopetrin-1-like OS=Lingula unguis OX=7574 GN=LOC106181265 PE=4 SV=1)

HSP 1 Score: 311.612 bits (797), Expect = 1.020e-90
Identity = 210/618 (33.98%), Postives = 332/618 (53.72%), Query Frame = 1 
Query: 1150 KNYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFE-----QNIGQTEIINL-HRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNI-ETTS--TRFDPNVTGSIQESSRASFQR----RKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQ 2964
            ++ LF I+S +Y++ ++ +  VLP+ EI       N +E FYI+LY V I+FL+Y+Y +LL++ T                                   ++    R  + N   T + E   ++ S+D   S H     G   LRL  +G G+ +M+ DGL FG   +   S   SP  C +  +AVR +  L++TF+QLYFIF+NSK+C HK++V+AR GLMHM A N+    + ++K+++ E      N   TE ++L H   + L      LKQ      ++P+  I   + T   P    T L C   D+M  V+  + PY+YPC VQY LI +A+L+  WRNI + TS  + F   +  +    ++   QR     +R I+   +C GS KG+FVG++ ++  I+ ++ F +LV+KP+ +  A+ + ++ EI L +   V  + A F++QDL F  +         L+ETLLLIS+  GVY+ S+ +IV G   +       +++   L LL++S+ +IFV  GLRR SYK  HE  KPGRELV FLL+ N A+W +++F+ R+ + V  +    +G   W +ISHI+ PL + FR  + + LA IW+ AY+
Sbjct:   14 RSSLFNILSGLYSIFVIILGAVLPIAEIFAQPVAINFFEAFYIYLYGVSIIFLIYVYAFLLQNAT-----------------------------------SEYTRKRAQQANNAHTAILEKS-RKVSIDSSGSHHT----GSFYLRLGAVGFGIGNMLLDGLRFGEFFEMDLS---SP--CSNILLAVRPMVHLVFTFVQLYFIFLNSKMCIHKYKVLARFGLMHMFATNICVWLRNLMKETLRELQHKAVNTSLTEYLSLQHFTPAHLRDATGVLKQGA---AEVPNYNISTNMTTRNPPI--LTLLDCQRRDIMGNVVDQAAPYLYPCAVQYSLIGSAILYTIWRNIGKRTSPLSTFYSTIQNNWSPKNKVQTQRPVCDNQRQIV---DCQGSTKGLFVGILLLVVTIISMIAFFVLVEKPSYQSIAVIVVHAAEITLHLITAVTVLAAFFRVQDLYFNIK-----KDIGLDETLLLISL-TGVYIFSIFSIVAGYYNTTTYGGTLIVVTGTLQLLESSLLTIFVLNGLRRRSYKPSHEESKPGRELVTFLLVCNIAMWGVNIFQTRRAE-VNPVQTDFYGNLLWVIISHISTPLNIFFRFHAAVCLANIWRNAYK 571
[Close]
BLAST of otopetrin-2 vs. TrEMBL
Match: A0A210Q965 (Otopetrin-2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT12734 PE=4 SV=1)

HSP 1 Score: 282.722 bits (722), Expect = 6.887e-78
Identity = 188/609 (30.87%), Postives = 334/609 (54.84%), Query Frame = 1 
Query: 1159 LFTIISAMYAMLLLTISVVLPVIEI--TTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPN-SSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLY-KLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQR--LEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQ-RKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQ 2964
            LF I+S +YAML++ +  V+P+ +I  T P  +   +EGFYI+LY V I+FLVY Y YLL+++T+          ++VK      ++++ D + + + R                       +++S D   + +     G   LRL  +  GV SMI+ GLLFG+   + +  N S+P H       VR L  L +TFIQLYF+F+NSK+C H+++ +AR GLMHM+A NL    + ++++++              R + T +  QR   + G +    + + + + ++Q       +   L C+G  LM  V+++S PY+YPC+V+Y +I A +L++ W+NI      +D N    I+  ++A     +R+     +CSGS +G+F+G+  ++A ++ +++F +L+   +   TAL++ +  E+ + +  ++A +LA  +MQ L +        I ++  LEE+LLLI +V G +   + +I+   + S++     +++ S+L + QA++Q++F+   LR+ + K  HER KPGRE V FLL+ N ALW +  FE  R   N   L++  +G   W +++H++IPL + +R  S + L+ IWK A++
Sbjct:  280 LFIIVSGLYAMLVVVMGCVMPIADIFATKPMPYL--FEGFYIYLYSVSIVFLVYAYVYLLQNKTVR-------LRKKVKR-----RMNSPDSNGSTSSRK----------------------RKYSFDVSRTYNT----GSFYLRLGAVAFGVGSMIQSGLLFGQFFYSESFSNCSNPLH------GVRPLLQLSFTFIQLYFVFLNSKMCIHRYKSLARFGLMHMVATNLCVWVENIVRETL--------------REIETYNFRQR---EAGTWLGPNVSNNQSVHQVQN--GSMTSAGILRCNGNSLMKSVVESSGPYLYPCSVEYSIICAGILYVMWKNIGRFQMGYDGNEVLDIESKAKA-----QRI---NVDCSGSSRGLFIGIFVLVATVITMIIFFVLIGSMSYLDTALKLEHLSEVVIYVLTSIAVILAFHRMQSLRYS-------IEKQIDLEESLLLIGLV-GEFTFGLFSIIAAAMDSQESNGFLVILSSVLGMFQATLQTVFLLHALRKSAGKREHERQKPGREFVTFLLVCNIALWSITTFEVLRSQANPMQLNY--YGVVAWNIVNHVSIPLTIFYRFHSTVCLSNIWKNAWR 805
[Close]
BLAST of otopetrin-2 vs. TrEMBL
Match: R7T6T3 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_165173 PE=4 SV=1)

HSP 1 Score: 267.7 bits (683), Expect = 1.903e-75
Identity = 181/598 (30.27%), Postives = 307/598 (51.34%), Query Frame = 1 
Query: 1189 MLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTS-TRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLD-NVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 2976
            M+L+   + LP+ +I +       +EGFYI+L+VV ++FL+Y+Y Y+LR +        P  + + +    S+ +D  DL A                        +   +RFS+   S        G   LRL  +G GV +MI +GL+ GR L+    P      C      VR +  L +TF QLYFIF+NS++C HK++ +AR GLMHM+A N+    + VI++++ +          +HR         +F   +  +        + L    +++         C   ++M  V++ + PY+YPCT++Y LI A +L++ W NI  ++ T   P+  G +++  R S            +C+G+ +G+F G+ T++A I+ L++F +LV  P+L+ +A+ + +  E+ L   A +A ++A  K++ L F            L+  L+LIS + GVY++SV +IV GR   +     F +  + L +LQA++Q++F+  GLRR      HER KPGRE V FLL+ N  +W ++ FE  + D N   L++  +G   W++ISH+  PL + +R  S + L+ IWK AY+ + +
Sbjct:    1 MILIVFGLCLPLADIFSSQLEVFIFEGFYIYLHVVSVLFLLYVYCYILRQRK------NPTKNSRAENRQNSL-ID--DLPAP-----------------------KHPHQRFSMSCSSHT------GSFYLRLGAIGFGVGAMIHEGLMLGRTLEYKMVPE-----CIHVLTLVRPVIQLTFTFFQLYFIFLNSRMCIHKYRTLARFGLMHMVATNICVWLRVVIQETVHD----------IHRSQGHKGKVNKFYCLDFNF--------LFLAGNESVA---------CIEQEIMGKVVENASPYLYPCTIEYSLIAAGILYIMWLNISKSAPTPSTPSDCGHLKKHLRMS-----------VDCAGANRGLFFGIFTLVATIISLIIFFVLVDIPHLQGSAVMVVHVSELTLYCLALIAVIVASVKIRQLRFDTNH-----KDELDGILILISQM-GVYVYSVFSIVAGRYGDDLITGIFTMATNALIMLQATVQTVFILNGLRRSPRSCFHERKKPGREFVTFLLVCNIGMWGINTFEVLRADSNPLALNY--YGFLPWSIISHVATPLAIFYRFHSTVCLSAIWKNAYKMKGN 509
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BLAST of otopetrin-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000564.1 (pep scaffold:Pmarinus_7.0:GL476591:206565:219203:-1 gene:ENSPMAG00000000506.1 transcript:ENSPMAT00000000564.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.9878 bits (123), Expect = 6.858e-7
Identity = 50/226 (22.12%), Postives = 96/226 (42.48%), Query Frame = 1 
Query: 1510 MDMKRFSLDYDSSEHHYD-EW--GGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNI 2178
            + M+R        +HH   +W  GGL L        + ++I D    G          +   HC S  +A+  +   I++ I +  +++  K C  ++Q + RLG+MH +A ++   F TVI++SI        ++I  HR                +  +   S  II+K +     E   T  +       D V+     ++ P  +++ L ++A+L++ W+N+
Sbjct:   61 LHMRRVDTSSIPMDHHAGAKWLKGGLAL------FALATIILDAFRIGYY--------TGMTHCESVALAIFPVLQAIFSIILVLLLWVYGKYCVREWQTLHRLGMMHTLATSILIWFNTVIEESI--------KVIKEHR--------------FSIINMGNGSITIIMKYRHVTYNETECTCQMNFCQMFYDSVL-----FLDPFNIEFSLFSSAMLYVMWKNM 245
[Close]
BLAST of otopetrin-2 vs. Ensembl Nematostella
Match: EDO39144 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAV2])

HSP 1 Score: 50.447 bits (119), Expect = 3.751e-6
Identity = 72/333 (21.62%), Postives = 147/333 (44.14%), Query Frame = 1 
Query: 2059 CHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKK----------------------------GIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVG----RLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRV--SYKTIHERDKP-------GRELVAFLLLANTALWCLHLFEQ--RKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSI 2928
            C+    M+ +I+ ++ ++YP  ++Y ++++ LL+  W +++       P    S+ ESS A+ +     I S+  C  S                              G  +G++T++  +V ++   +  +K   R+      Y   I + +    A+++    +  + F P   S   +  + +T+LL+  ++G ++ +   IVVG    +   +K    F L+ ++ + +Q ++Q++FV   L R   SY     RD          R++ A L + N ALW ++ FE   ++++N       V     W+V+ HI  PL + FR+ S+
Sbjct:  375 CNATMAMENLIKKANYFLYPFEIEYSVMSSGLLFNLWYSLK------QPPDYNSV-ESSDANSETNGNGIFSSKFCGLSAACSTCCKCKPESSPQGHARTVAFWKNAICGFSIGIITLVGLLVLIIC--VYAEKDVARINPWNAYYGVRILIYIMMAFASLVGINCL--VHFHPSSSS---SHTIVDTVLLMIGISGAFILTGFQIVVGFTELKSKRDKTYVTFFLLDAVAATVQFTVQTLFVIRALLRSAESYDNEVYRDVSIRTLSWFIRQIAALLSIVNFALWAMNTFEINFKEMNNP---EISVIDSTVWSVVRHIAYPLCIFFRLHSV 690
[Close]
BLAST of otopetrin-2 vs. Ensembl Medaka
Match: otop2 (otopetrin 2 [Source:NCBI gene;Acc:101171833])

HSP 1 Score: 68.9366 bits (167), Expect = 1.835e-11
Identity = 91/451 (20.18%), Postives = 184/451 (40.80%), Query Frame = 1 
Query: 1687 HCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQ-----KPNLRLTALRISYSFEIALIMSATVATVLAC--FKMQDLLFQPRFHSRCITQRLEETLLLISMVAGV--------YLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPG------------------RELVAFLLLANTALWCLHLFEQR-KLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIAL 2937
            HC S+      +  L++  +Q YF++I+SK C    + I+  GLM  ++ NL+     V      E+++ QT + +    ++ LS    ++ + G                        +    C       GV + +  Y+YP  ++Y L  +A+ ++ W+N+   ++           E S+ +F+   + I+          G  VG++ +IA +   +V+ I ++       ++   A+ + +   I ++   +V+TV+ C  FK+         H   ++++     L + ++ G         Y   +A I  G   ++   +   L   +L + Q  +Q+ F+  GL R  +  + + +K                    RE+  FLLL N  LW +  F  R + D+   +    F    WA I ++ +P  + +RM S+ +L
Sbjct:  165 HCDSAVKVAFPVVQLVFVIVQTYFLWIHSKDCVQLQKNISCCGLMLTLSTNLALWMAAVT-----EESLHQTVLPDYEVNVTKLSARSLYISKAG------------------------YGDDSCKCSHTSCGVFKEAYYYLYPFNIEYSLFASAMSFVMWKNVGRVAS-----------EHSKHNFKFTLKDIV---------IGPVVGILLVIAGLATFIVYEIEMKTYRSDDDDINDHAVMMHFIMNIVIVTMMSVSTVIGCAIFKVD--------HREHVSEKNPTRSLDVGLLVGASMGQFIISYFSIIATIATG---AKGHLNRLNLAWGVLMVFQLGLQNFFIIEGLHREPFHEVEDNEKSEESCFEGHKHKLLWKRRVLREVCVFLLLGNIILWIMPAFGARPQFDHDTEVEFYKFNM--WAAIVNVGLPFGIFYRMHSVASL 553
[Close]
BLAST of otopetrin-2 vs. Ensembl Medaka
Match: otop2 (otopetrin 2 [Source:NCBI gene;Acc:101171833])

HSP 1 Score: 55.0694 bits (131), Expect = 3.928e-7
Identity = 55/265 (20.75%), Postives = 112/265 (42.26%), Query Frame = 1 
Query: 1687 HCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQ-----KPNLRLTALRISYSFEIALIMSATVATVLAC 2466
            HC S+      +  L++  +Q YF++I+SK C    + I+  GLM  ++ NL+     V ++S             LH+   TL      ++ + L KL             +  P   +    C       GV + +  Y+YP  ++Y L  +A+ ++ W+N+   ++           E S+ +F+   + I+          G  VG++ +IA +   +V+ I ++       ++   A+ + +   I ++   +V+TV+ C
Sbjct:  168 HCDSAVKVAFPVVQLVFVIVQTYFLWIHSKDCVQLQKNISCCGLMLTLSTNLALWMAAVTEES-------------LHQTPLTLQS----VRNQQLTKL------------FSCHPAAGYGDDSCKCSHTSCGVFKEAYYYLYPFNIEYSLFASAMSFVMWKNVGRVAS-----------EHSKHNFKFTLKDIV---------IGPVVGILLVIAGLATFIVYEIEMKTYRSDDDDINDHAVMMHFIMNIVIVTMMSVSTVIGC 383
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BLAST of otopetrin-2 vs. Planmine SMEST
Match: SMESG000031517.1 (SMESG000031517.1)

HSP 1 Score: 1815.43 bits (4701), Expect = 0.000e+0
Identity = 938/940 (99.79%), Postives = 939/940 (99.89%), Query Frame = 1 
Query:  157 HGNFPSVINLYAAGKKEESLSDMSDYAATNSSISSEIRYQPISYVEDLSQSNFLSPIPVALPKNQIYFPQDRMGNCGSPVXXXXXXXXXXXXXCNAEKERRXXXXXXXXXXXDEERLPKTVRTVRARASQASDAPYSTPNKSGIYHITNVGHPIVHHPLSKDMVQVNPDPLILAQXXXXXXXXXXXXXGKTVRLSGRRVVVGEGRDAQIIMGHIPQSCQYLQNRVDCSLSRGAAESIGLHSQAADSGISNTSPETQSSTEFYQRKLHDTIISGKVSHSSSGRFSVPSIGITGTGMGPKLHHTPRLPSGQYPQSILKFSKDHFSLIQITADFKNYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 2976
            HGNFPSVINLYAAGKKEESLSDMSDYAATNSSISSEIRYQPISYVEDLSQSNFLSPIPVALPKNQIYFPQDRMGNCGSPVSSSSDSDTDSDTTCNAEKERRNSTTSTSTNSSDEERLPKTVRTVRARASQASDAPYSTPNKSGIYHITNVGHPIVHHPLSKDMVQVNPDPLILAQSSPSSRTASSSNSGKTVRLSGRRVVVGEGRDAQIIMGHIPQSCQYLQNRVDCSLSRGAAESIGLHSQAADSGISNTSPETQSSTEFYQRKLHDTIISGKVSHSSSGRFSVPSIGITGTGMGPKLHHTPRLPSGQYPQSILKFSKDHFSLIQITADFKNYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALR DDQGDRFCEMNKMETGVHE+DMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFLLIGSILSLLQASIQSIFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS
Sbjct:   12 HGNFPSVINLYAAGKKEESLSDMSDYAATNSSISSEIRYQPISYVEDLSQSNFLSPIPVALPKNQIYFPQDRMGNCGSPVSSSSDSDTDSDTTCNAEKERRNSTTSTSTNSSDEERLPKTVRTVRARASQASDAPYSTPNKSGIYHITNVGHPIVHHPLSKDMVQVNPDPLILAQSSPSSRTASSSNSGKTVRLSGRRVVVGEGRDAQIIMGHIPQSCQYLQNRVDCSLSRGAAESIGLHSQAADSGISNTSPETQSSTEFYQRKLHDTIISGKVSHSSSGRFSVPSIGITGTGMGPKLHHTPRLPSGQYPQSILKFSKDHFSLIQITADFKNYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRNDDQGDRFCEMNKMETGVHEIDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFLLIGSILSLLQASIQSIFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 951
[Close]
BLAST of otopetrin-2 vs. Planmine SMEST
Match: SMESG000031517.1 (SMESG000031517.1)

HSP 1 Score: 1806.57 bits (4678), Expect = 0.000e+0
Identity = 938/950 (98.74%), Postives = 939/950 (98.84%), Query Frame = 1 
Query:  157 HGNFPSVINLYAAGKKEESLSDMSDYAATNSSISSEIRYQPISYVEDLSQSNFLSPIPVALPKNQIYFPQDRMGNCGSPVXXXXXXXXXXXXXCNAEKERRXXXXXXXXXXXDEERLPKTVRTVRARASQASDAPYSTPNKSGIYHITNVGHPIVHHPLSKDMVQVNPDPLILAQXXXXXXXXXXXXXGKTVRLSGRRVVVGEGRDAQIIMGHIPQSCQYLQNRVDCSLSRGAAESIGLHSQAADSG----------ISNTSPETQSSTEFYQRKLHDTIISGKVSHSSSGRFSVPSIGITGTGMGPKLHHTPRLPSGQYPQSILKFSKDHFSLIQITADFKNYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 2976
            HGNFPSVINLYAAGKKEESLSDMSDYAATNSSISSEIRYQPISYVEDLSQSNFLSPIPVALPKNQIYFPQDRMGNCGSPVSSSSDSDTDSDTTCNAEKERRNSTTSTSTNSSDEERLPKTVRTVRARASQASDAPYSTPNKSGIYHITNVGHPIVHHPLSKDMVQVNPDPLILAQSSPSSRTASSSNSGKTVRLSGRRVVVGEGRDAQIIMGHIPQSCQYLQNRVDCSLSRGAAESIGLHSQAADSG          ISNTSPETQSSTEFYQRKLHDTIISGKVSHSSSGRFSVPSIGITGTGMGPKLHHTPRLPSGQYPQSILKFSKDHFSLIQITADFKNYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALR DDQGDRFCEMNKMETGVHE+DMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFLLIGSILSLLQASIQSIFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS
Sbjct:   12 HGNFPSVINLYAAGKKEESLSDMSDYAATNSSISSEIRYQPISYVEDLSQSNFLSPIPVALPKNQIYFPQDRMGNCGSPVSSSSDSDTDSDTTCNAEKERRNSTTSTSTNSSDEERLPKTVRTVRARASQASDAPYSTPNKSGIYHITNVGHPIVHHPLSKDMVQVNPDPLILAQSSPSSRTASSSNSGKTVRLSGRRVVVGEGRDAQIIMGHIPQSCQYLQNRVDCSLSRGAAESIGLHSQAADSGSVVCIKEDRGISNTSPETQSSTEFYQRKLHDTIISGKVSHSSSGRFSVPSIGITGTGMGPKLHHTPRLPSGQYPQSILKFSKDHFSLIQITADFKNYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRNDDQGDRFCEMNKMETGVHEIDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFLLIGSILSLLQASIQSIFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFESS 961
[Close]
BLAST of otopetrin-2 vs. Planmine SMEST
Match: SMESG000028508.1 (SMESG000028508.1)

HSP 1 Score: 213.772 bits (543), Expect = 2.913e-56
Identity = 186/728 (25.55%), Postives = 344/728 (47.25%), Query Frame = 1 
Query:  871 LHSQAADSGISNTSPETQSSTEFYQRKLHDTIISGKVSHSSSGRFSVPSIGITGTGMGPKLHHTPRLPSGQYPQSILKFSK-DHFSLIQITADFKNYLFTIISAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLLRDQTISRFHLGPLCSRQVK----------------ALNTSIQVDNADLSA------TLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISP---EKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAA---LLWLSWRNIETTSTRFDPNVT-GSIQESSRASFQRRKRLI--LSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQD--LLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWK 2952
            L+SQAADSGISNTSP+T SSTEFYQR L D+    K +  +S   + P  G                  G  P SILK  + ++ SL    ++F+  +  I+S +Y  LL TI +VL + +        +  E F IF + V I+FL   +    + Q   RF +    + + +                 L      D++++++      +  +   D   R C++N +   + E                       L ++++L + ++SMIR+ +     ++ + +       C S  + VR   SL++T  Q YF+ ++ K    KF      G++HM A N++ +   ++                      +     +F+K +    L+ P  E +L  +  +SP   + N T   C   D+M+ +   S+ Y+YP ++QY  +T     LL  S  +++  +     N T  S++ESS  + + R      L+   C  S KG F+GL +++ +++ L++ +I  +K +L+L  ++ISY  E+ L +  T+ TV + + ++D  LL  P   +R   +     ++  S+  GVYL++++ I+  +     P +PF+++ S+ +++  ++Q+IFV   + R+S        KP +E V+F+L+ N A+W L +F + +      +   ++G   W +I  +++PL L++++ S+I+LAVIWK
Sbjct: 1234 LNSQAADSGISNTSPDTLSSTEFYQRNLEDSRFVSKCNRLTS---NFPWHG------------------GNIPPSILKHRRRNNQSLDYSVSNFRTLICQILSIIYIFLLSTIILVLAISDQNDVPGSKDLLESFQIFQFSVSILFLTVFHLSDCKGQP-KRFPISTFITHRFQDTEPEHCLIVSNPVSFELQEKTNRDSSEINSFPENIVSNEILNIDGSTRSCQINDLSRNLFES----------------------LFKVSILVVSIISMIRNAVELATEIEIAQANAERLQDCHSIFIIVRSFLSLLFTIFQTYFVLLDFKSIVTKFTHPIIFGVVHMTATNINSITHNIV----------------------SYKTLMKFIKTKSNL-LEAPVTESVLTTRNILSPNILKMNGTS--CFTADIMEQISSISETYLYPFSIQYSALTTVINLLLLSSMDSVQDVNFSLPVNSTFRSVRESSSETERLRSSNCRKLTAINCKNSNKGFFIGLFSLLVSVISLIMLYIFSKKSSLKLVGMKISYLTEMILTIITTLVTVTSLYHLRDISLLSYPNNINR--IESANRIVMFSSLFGGVYLYNISCILAWKTALNAPSAPFVMVSSLCTIIHGTLQTIFVLLTIARMSLSDPIPIKKPKKEFVSFILMNNVAIWGLKIFTELQHSTSETIPEIIYGPVHWVLIKRLSVPLTLLYQIDSVISLAVIWK 1890
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BLAST of otopetrin-2 vs. Planmine SMEST
Match: SMESG000018672.1 (SMESG000018672.1)

HSP 1 Score: 141.354 bits (355), Expect = 1.667e-34
Identity = 164/635 (25.83%), Postives = 287/635 (45.20%), Query Frame = 1 
Query: 1180 MYAMLLLTISVVLP-------VIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYGYLL-----------RDQ----TISRFHLGPLCSRQV----KALNTS-IQVDNADLSATLALRTDDQGDRFCEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGG--LLLRLTVLGMGVVSMIRDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASFQRRKRLILST---TECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSP-------FXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHE-RDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQ 2964
            ++AM  L   +V+P       + E  T HA++   E F I  YV  I  + ++ GY+            +D      I+R  L  L S++V       NT  ++++N     T  L T++  + F   N  +   H ++ K F+    ++ +   E  G  L LRL  +G G   M+ DG    +V D     NS    C +     +    L Y FIQ +FIF   +    K + + R  L H+   N+   FKTV+    +E N    E+++ H+  S                      +I +   +TI  E              D +  +  PY++PC ++Y LI+AA+ +           +    V G+  +   +S + + ++++     +EC  S KG+FVGL+  +  +V L +F +  +    +  A+ +    EI L++S+++A V A  KM+ L    RF      + L++ LLL+ + AGV+ +++   +     S K  +          L  S+  ++Q+ +Q +FV    R+ + ++ H+ R KPGR LV FL++ N ALW + +FE ++ D    +  K + +  W++I+H  +PLI+ FR  S I L  IW +AY+
Sbjct:   46 LFAMSQLFFGIVIPLSDSFVTISEKETEHAYY--LEAFLIIQYVTAIASVFFLQGYVYIHDCYLKKNNKKDDPCQDEITR-ELVDLDSQKVTFKLSHQNTEDVELENISNDDTTHLSTNNLSNAF---NTDDKSSH-LENKLFTSQQFNNYYVIKETNGINLYLRLGAVGFGFGVMVHDGF---KVADQVRLQNS---FCHNQLWTPKQCLHLAYIFIQTFFIFKYHRAIFLKHKAVIRFILYHLTISNICQWFKTVV----YEIN---HELLD-HKNTS----------------------QINIHGNSTIRHE---------NKTCTDQLSYSVSPYLFPCAIEYSLISAAIFY-----------KMLQRVGGNEHDEKHSSDKLQTQVVVKNIKYSECHRSHKGLFVGLLFFMVTLVGLAIFLLFKKTDKTQTLAVMVYQVSEIILLVSSSIALVCAFIKMRGL----RFCQLSEEEALDDNLLLVGL-AGVFAYNLFLFISTIDSSNKLDNSKHSLSIILFLCKSMTEIIQSLLQVLFVLESSRKCA-QSFHDVRVKPGRSLVTFLIVTNLALWTVSIFEAKRADE-HLIFTKYYQKTPWSIITHTLLPLIIFFRFHSSICLTDIWTKAYK 610
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BLAST of otopetrin-2 vs. Planmine SMEST
Match: SMESG000018671.1 (SMESG000018671.1)

HSP 1 Score: 137.887 bits (346), Expect = 2.222e-33
Identity = 163/641 (25.43%), Postives = 276/641 (43.06%), Query Frame = 1 
Query: 1180 MYAMLLLTISVVLPV----IEITTP---HAFFNAYEGFYIFLYVVGIMFLVYIYGYLL-----RDQTISR-FHLGPLCSRQVKALNTSIQVDNADLS----ATLALRTDDQG-DRFCEMNKMETGVHEMDMKRFSLDYDSSE--------------HHYDEWGGLLLRLTVLGMGVVSMIRDGLLFGRV--LDTSNSPNS--SPAHCRSSQVAVRCLFSLIYTFIQLYFIFINSKICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHRPMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGDLMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSIQESSRASF-QRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQKPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQRLEETLLLISMVAGVYLHSVANIVV---------GRLYSEKPPSPFXXXXXXXXXXXXXXXXXFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKLDNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQ 2964
            ++AM  L   +V+P+    + I+     HA++   E F I  Y   I+F+ Y+ GY+        Q I +    G L  ++ K     I  D  D+S     T  L+ + Q   R  E++       ++ +  F   + SSE                  E   L LRL  +G G   M+ DG        L+  N  N   +P HC            L Y F+Q +FIF   +I   K + I R  L +++  N+   FKTV+    +E N    E  N     S LS       Q+  Y               T+SP                        +++PC ++Y LI+AA+ +   + +                 S R  +  + +R+I   +EC  S +G+FVGL+  +  +V + +F +  +K   + +++ +    EI L++S+ +  V A  KM+ L F+         Q L++ LLLI + +GV+ +++   +          G  YS        +  S+  ++Q++IQ +FV  G R+ + K +H + KPGR LV FL++ N ALW + +FE ++ D    +  K + +  W++I+H  +PLI+ FR  S I L  IW ++Y+
Sbjct:   45 LFAMCQLFCGIVIPLSDSFVTISDSGMGHAYY--LEAFLIIQYFSAILFVFYLQGYIFMCERRNKQNIKQEIENGILDEKKKKKSVDVIAEDKLDISESPKVTFDLKAEVQNHQRSNEISITSMQEDDIFLTSFKNSHPSSEVSSIASQNAEKLSIMRDHEGINLYLRLGAVGFGFGVMVHDGFKIADKFRLEGENCHNELWTPKHC----------LHLSYIFVQTFFIFKYHRIIFLKHKPIVRFILYNLVTSNICQWFKTVV----YEINHELVEHRNKISMKSNLSENYSNCSQQLSY---------------TVSP------------------------FLFPCAIEYSLISAAIFYKMLQKVGRKHR----------DHSYREKYIAQGERIIAKYSECHRSHRGLFVGLLFFMVTLVGVAIFFLFKKKIATQSSSVIVYQLSEIMLLVSSIITLVWAFIKMRTLSFRQLTEE----QALDDNLLLIGL-SGVFSYNLFLFISTIDSFIRLPGHQYS--LIIILFICKSLTEMVQSTIQVLFVLEGSRKGTTKELHIKLKPGRSLVTFLIIINLALWIVSIFEAKRSDE-HLIFTKYYQKTPWSIITHTLLPLIIFFRFHSSICLMDIWSKSYR 612
The following BLAST results are available for this feature:
BLAST of otopetrin-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of otopetrin-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
otpl-87.161e-2823.74OToPetrin-Like [Source:UniProtKB/TrEMBL;Acc:G5EDX... [more]
otpl-17.465e-2524.09OToPetrin-Like [Source:UniProtKB/TrEMBL;Acc:O4506... [more]
otpl-18.717e-2524.00OToPetrin-Like [Source:UniProtKB/TrEMBL;Acc:O4506... [more]
otpl-11.570e-2424.00OToPetrin-Like [Source:UniProtKB/TrEMBL;Acc:O4506... [more]
otpl-53.374e-2425.23OToPetrin-Like [Source:UniProtKB/TrEMBL;Acc:G4SFC... [more]
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BLAST of otopetrin-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
OtopLc5.305e-5924.88gene:FBgn0259150 transcript:FBtr0331168[more]
OtopLc5.538e-5924.88gene:FBgn0259150 transcript:FBtr0346834[more]
OtopLc6.292e-5924.88gene:FBgn0259150 transcript:FBtr0331167[more]
OtopLb2.649e-4624.12gene:FBgn0031514 transcript:FBtr0077609[more]
OtopLb2.668e-4624.23gene:FBgn0031514 transcript:FBtr0344796[more]
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BLAST of otopetrin-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of otopetrin-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of otopetrin-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of otopetrin-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 1
Match NameE-valueIdentityDescription
sp|B7Z0W9|OTOP_DROME6.307e-5824.88Proton channel OtopLc OS=Drosophila melanogaster O... [more]
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BLAST of otopetrin-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3HXZ44.168e-9332.77otopetrin-2 OS=Lingula unguis OX=7574 GN=LOC106159... [more]
A0A267EC746.843e-9131.85Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1S3KEJ41.020e-9033.98otopetrin-1-like OS=Lingula unguis OX=7574 GN=LOC1... [more]
A0A210Q9656.887e-7830.87Otopetrin-2 OS=Mizuhopecten yessoensis OX=6573 GN=... [more]
R7T6T31.903e-7530.27Uncharacterized protein OS=Capitella teleta OX=283... [more]
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BLAST of otopetrin-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of otopetrin-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000000564.16.858e-722.12pep scaffold:Pmarinus_7.0:GL476591:206565:219203:-... [more]
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BLAST of otopetrin-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of otopetrin-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO391443.751e-621.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of otopetrin-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
otop21.835e-1120.18otopetrin 2 [Source:NCBI gene;Acc:101171833][more]
otop23.928e-720.75otopetrin 2 [Source:NCBI gene;Acc:101171833][more]
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BLAST of otopetrin-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000031517.10.000e+099.79SMESG000031517.1[more]
SMESG000031517.10.000e+098.74SMESG000031517.1[more]
SMESG000028508.12.913e-5625.55SMESG000028508.1[more]
SMESG000018672.11.667e-3425.83SMESG000018672.1[more]
SMESG000018671.12.222e-3325.43SMESG000018671.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024125 ID=SMED30024125|Name=otopetrin-2|organism=Schmidtea mediterranea sexual|type=transcript|length=3068bp
GTTTAAATTAATCAAATAAGTCAATTGATCATATAGGAAATTTTGAATTA
AAATTTAGTTTCTCGTATTATGAAATTAAATTATCGAATTTATAATTAAA
TAATTTCGAAAAAAAAATCTCTCATGTATGAAAGTAGCTCAGAATCATCT
ATTGAACATGGGAATTTTCCATCTGTCATCAATCTCTATGCTGCTGGGAA
AAAAGAGGAATCTTTGTCAGATATGAGCGATTATGCTGCAACGAATTCCA
GCATAAGTTCTGAAATAAGATATCAACCGATAAGTTATGTTGAAGATTTA
TCTCAAAGCAATTTTCTTTCACCGATTCCAGTAGCTTTGCCAAAAAATCA
AATTTATTTCCCCCAAGACAGAATGGGGAATTGTGGATCACCTGTGTCGT
CGTCCTCTGATTCCGATACAGACTCAGATACGACTTGTAATGCTGAAAAA
GAAAGACGAAATAGCACGACGAGCACCAGCACCAACAGCAGCGATGAAGA
AAGATTGCCTAAAACAGTACGTACAGTGCGTGCAAGAGCTTCACAAGCTT
CAGATGCTCCATATTCAACTCCAAACAAAAGTGGAATTTACCACATCACT
AATGTCGGACATCCAATAGTCCATCATCCGTTATCAAAGGATATGGTTCA
AGTAAACCCGGACCCTCTAATATTAGCTCAATCTTCCCCAAGTTCTAGAA
CAGCGAGTTCTAGTAATAGCGGTAAAACCGTCAGACTCAGTGGTCGGCGA
GTAGTTGTTGGAGAAGGACGAGATGCTCAAATAATCATGGGTCATATTCC
ACAATCCTGTCAATATCTACAAAACCGAGTCGACTGTTCGCTTTCTCGAG
GAGCAGCAGAAAGTATCGGACTTCATAGTCAGGCAGCTGATTCCGGCATC
AGCAATACAAGTCCGGAAACTCAAAGCTCAACGGAATTTTACCAGCGAAA
ACTGCACGACACCATTATTAGCGGCAAAGTCAGTCACTCATCGAGTGGCA
GATTTTCTGTCCCATCTATCGGAATTACTGGAACAGGAATGGGGCCAAAA
CTGCATCATACTCCCAGATTACCCAGCGGCCAATATCCTCAATCTATACT
CAAATTTTCCAAAGATCATTTTTCGCTCATTCAAATTACTGCTGATTTTA
AAAATTATCTTTTTACGATCATATCAGCCATGTACGCGATGTTACTTCTT
ACAATCAGCGTTGTGCTTCCAGTGATTGAAATCACTACTCCACATGCATT
TTTCAATGCTTATGAAGGATTCTACATATTTCTCTATGTGGTTGGTATCA
TGTTCCTGGTTTACATATATGGTTATCTACTACGCGATCAAACTATATCA
CGGTTTCATTTGGGCCCACTCTGTTCAAGGCAGGTAAAAGCACTTAACAC
ATCAATCCAGGTTGATAATGCAGATTTGTCTGCGACATTAGCGTTGCGAA
CTGACGATCAAGGTGATAGATTTTGTGAAATGAATAAAATGGAGACGGGC
GTGCACGAAATGGACATGAAGAGATTTTCTCTCGATTATGATTCGTCAGA
ACATCATTATGATGAATGGGGTGGCTTACTACTCAGGCTCACAGTATTGG
GCATGGGAGTAGTAAGCATGATCAGAGATGGTTTATTATTTGGAAGGGTT
TTGGATACAAGCAATTCCCCGAATTCAAGTCCAGCACATTGTCGCTCATC
CCAAGTGGCAGTTCGATGCTTATTCTCTTTGATATACACTTTCATTCAGT
TATATTTTATATTCATCAATTCAAAGATTTGTACACATAAATTCCAAGTC
ATTGCCAGATTAGGATTAATGCACATGATTGCAGTCAATTTATCAGGGTT
GTTTAAAACCGTCATAAAGGATTCTATATTCGAGCAAAATATCGGGCAAA
CGGAAATAATAAATTTACACAGACCAATGTCGACCCTCTCGCCGACACAG
CGGTTTCTCAAACAAGAAGGATTGTATAAATTGAAAATTCCTTCACCAGA
GATAATTCTCAAAATTCAGACGACAATTTCACCAGAAAAGAATTGGACAA
AATTGCTTTGTCATGGCGGAGATCTCATGGATGGAGTAATCCAAGCCTCG
GACCCTTACATCTATCCCTGTACAGTGCAATATTGTTTAATTACTGCTGC
ACTTCTATGGTTGTCATGGAGAAATATTGAAACCACAAGCACAAGATTCG
ATCCAAACGTGACCGGATCAATCCAAGAAAGTTCTAGAGCATCATTTCAA
AGACGCAAACGTCTTATTTTATCCACAACTGAATGTTCAGGGTCAAAAAA
GGGTATATTTGTGGGATTAGTAACAATGATTGCTGCAATTGTTGACCTAG
TCGTCTTTCATATTTTGGTTCAAAAACCAAACCTGCGTCTAACTGCTCTA
CGTATCAGTTATTCTTTTGAAATCGCTCTTATTATGTCAGCTACTGTCGC
TACTGTTTTGGCTTGTTTCAAAATGCAAGATTTATTATTCCAACCGAGAT
TTCATTCTCGATGTATAACTCAGAGATTAGAAGAGACACTATTGTTGATT
TCAATGGTAGCGGGCGTGTATTTGCATTCAGTGGCAAATATTGTCGTTGG
CCGCCTCTATTCAGAAAAGCCACCATCGCCATTCCTACTCATAGGATCAA
TTCTTTCACTTCTTCAAGCAAGCATACAAAGCATATTTGTCTGTACAGGC
CTTCGTAGAGTTTCTTATAAGACAATTCACGAACGAGACAAACCAGGTAG
AGAACTGGTGGCCTTTTTGCTGCTAGCAAACACCGCATTATGGTGCCTCC
ATTTATTTGAACAGCGTAAGTTAGACAATGTGTTCTTTCTCCATCACAAA
GTATTTGGTCAATGGACATGGGCCGTTATCAGCCATATAACTATCCCACT
AATTTTGATGTTCCGAATGGTCTCCATAATTGCCTTGGCAGTTATTTGGA
AGCAAGCCTATCAATTTGAATCTAGTTAAGTAAGGTTACCGTTTTTTTGT
GATACAGCCAGTATTATCCTTAGGCAAATCTCGTTAAATATCATTTAAGA
AATGTGCTTTTCGATGTT
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protein sequence of SMED30024125-orf-1

>SMED30024125-orf-1 ID=SMED30024125-orf-1|Name=SMED30024125-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=952bp
MYESSSESSIEHGNFPSVINLYAAGKKEESLSDMSDYAATNSSISSEIRY
QPISYVEDLSQSNFLSPIPVALPKNQIYFPQDRMGNCGSPVSSSSDSDTD
SDTTCNAEKERRNSTTSTSTNSSDEERLPKTVRTVRARASQASDAPYSTP
NKSGIYHITNVGHPIVHHPLSKDMVQVNPDPLILAQSSPSSRTASSSNSG
KTVRLSGRRVVVGEGRDAQIIMGHIPQSCQYLQNRVDCSLSRGAAESIGL
HSQAADSGISNTSPETQSSTEFYQRKLHDTIISGKVSHSSSGRFSVPSIG
ITGTGMGPKLHHTPRLPSGQYPQSILKFSKDHFSLIQITADFKNYLFTII
SAMYAMLLLTISVVLPVIEITTPHAFFNAYEGFYIFLYVVGIMFLVYIYG
YLLRDQTISRFHLGPLCSRQVKALNTSIQVDNADLSATLALRTDDQGDRF
CEMNKMETGVHEMDMKRFSLDYDSSEHHYDEWGGLLLRLTVLGMGVVSMI
RDGLLFGRVLDTSNSPNSSPAHCRSSQVAVRCLFSLIYTFIQLYFIFINS
KICTHKFQVIARLGLMHMIAVNLSGLFKTVIKDSIFEQNIGQTEIINLHR
PMSTLSPTQRFLKQEGLYKLKIPSPEIILKIQTTISPEKNWTKLLCHGGD
LMDGVIQASDPYIYPCTVQYCLITAALLWLSWRNIETTSTRFDPNVTGSI
QESSRASFQRRKRLILSTTECSGSKKGIFVGLVTMIAAIVDLVVFHILVQ
KPNLRLTALRISYSFEIALIMSATVATVLACFKMQDLLFQPRFHSRCITQ
RLEETLLLISMVAGVYLHSVANIVVGRLYSEKPPSPFLLIGSILSLLQAS
IQSIFVCTGLRRVSYKTIHERDKPGRELVAFLLLANTALWCLHLFEQRKL
DNVFFLHHKVFGQWTWAVISHITIPLILMFRMVSIIALAVIWKQAYQFES
S*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000240body wall musculature
PLANA:0002056medial muscle cell
PLANA:0003001lateral region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR014760Serum_albumin_N
IPR027417P-loop_NTPase
IPR004878Otopetrin
Vocabulary: cellular component
TermDefinition
GO:0005615extracellular space
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR004878OtopetrinPFAMPF03189Otopetrincoord: 487..931
e-value: 5.2E-87
score: 292.5
IPR004878OtopetrinPANTHERPTHR21522OTOPETRINcoord: 338..947
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 87..151
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 186..204
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 110..125
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 87..101
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 186..205
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 136..151
NoneNo IPR availableTMHMMTMhelixcoord: 383..403
NoneNo IPR availableTMHMMTMhelixcoord: 760..782
NoneNo IPR availableTMHMMTMhelixcoord: 346..368
NoneNo IPR availableTMHMMTMhelixcoord: 878..897
NoneNo IPR availableTMHMMTMhelixcoord: 728..750
NoneNo IPR availableTMHMMTMhelixcoord: 485..507
NoneNo IPR availableTMHMMTMhelixcoord: 835..857
NoneNo IPR availableTMHMMTMhelixcoord: 806..825
NoneNo IPR availableTMHMMTMhelixcoord: 917..939
NoneNo IPR availableTMHMMTMhelixcoord: 527..549