Non-specific serine/threonine protein kinase

Overview
NameNon-specific serine/threonine protein kinase
Smed IDSMED30024109
Length (bp)2419
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Non-specific serine/threonine protein kinase (SMED30024109) t-SNE clustered cells

Violin plots show distribution of expression levels for Non-specific serine/threonine protein kinase (SMED30024109) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Non-specific serine/threonine protein kinase (SMED30024109) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Non-specific serine/threonine protein kinase (SMED30024109) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30024109

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30024109SMESG000074914.1 dd_Smed_v4_11891_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30024109SMESG000074914.1 dd_Smed_v4_11891_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30024109SMESG000074914.1 dd_Smed_v4_11891_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30024109SMESG000074914.1 dd_Smed_v4_11891_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30024109SMESG000074914.1 dd_Smed_v6_11891_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 15 [Source:HGNC Symbol;Acc:HGNC:31689])

HSP 1 Score: 117.472 bits (293), Expect = 3.832e-26
Identity = 69/207 (33.33%), Postives = 110/207 (53.14%), Query Frame = 3 
Query: 1638 FVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRN-VKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
             VQ +    +  ++   +E + GGS++  L+  W P+    IK ++ QIL+GLK+LH N+I+HR++   N+LV+     VK+  F TSK L G       + F G  +    Y+APE++++  + YGA ADIWS G  ++E+   KPP F    E    + K      +  + E + ++ + F+  C  PDP +RAT  EL    FL
Sbjct:  709 IVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAG--VNPCTETFTGTLQ----YMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPP-FHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFL 908
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Match: MAP3K5 (mitogen-activated protein kinase kinase kinase 5 [Source:HGNC Symbol;Acc:HGNC:6857])

HSP 1 Score: 112.849 bits (281), Expect = 1.097e-24
Identity = 66/210 (31.43%), Postives = 120/210 (57.14%), Query Frame = 3 
Query: 1641 VQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            VQ +    +  F+   +E + GGS++  L+  W PL +++  I  ++ QIL+GLK+LH N+I+HR++   N+L++    V K+  F TSK L G    +  + F G    + +Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + E + ++ K F+  C  PDP +RA   +L  ++FL +
Sbjct:  738 VQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTG----TLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKV-HPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKV 940
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Match: PAK1 (p21 (RAC1) activated kinase 1 [Source:HGNC Symbol;Acc:HGNC:8590])

HSP 1 Score: 104.76 bits (260), Expect = 8.683e-23
Identity = 82/270 (30.37%), Postives = 142/270 (52.59%), Query Frame = 3 
Query: 1473 KLDEGDFSELFKAKWGAKFEDVLIKKY---EKSSKNLGDNQDILNELITYQITKSQPRFVQLIR--ICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFL--SEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 2258
            K+ +G    ++ A   A  ++V IK+    ++  K L     I+NE++  +  K+ P  V  +   +  DE  L+ ++E + GGS+T  + +   +    I     + LQ L+FLH N++IHR++ + NIL+  + +VKL  F       G+  Q   ++    T   + Y +APEVV RK YG + DIWS G++ +E+I G+PPY    +E  +  +  I  +G   L   EK+ +  + F+  CL  D ++R + +EL +++FL I K
Sbjct:  275 KIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKEL-----IINEILVMRENKN-PNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETC-MDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDF-------GFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYL---NENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAK 525
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Match: PAK2 (p21 (RAC1) activated kinase 2 [Source:HGNC Symbol;Acc:HGNC:8591])

HSP 1 Score: 103.219 bits (256), Expect = 3.016e-22
Identity = 80/269 (29.74%), Postives = 139/269 (51.67%), Query Frame = 3 
Query: 1473 KLDEGDFSELFKAKWGAKFEDVLIKK--YEKSSKNLGDNQDILNELITYQITKSQPRFVQLIR--ICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFL--SEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 2258
            K+ +G    +F A   A  ++V IK+   +K  K     + I+NE++  +  K+ P  V  +   +  DE F+  ++E + GGS+T  + +   +    I     + LQ L+FLH N++IHR++ + N+L+    +VKL  F       G+  Q   ++    T   + Y +APEVV RK YG + DIWS G++ +E++ G+PPY    +E  +  +  I  +G   L   EK+    + F+  CL  D ++R + +EL ++ FL + K
Sbjct:  254 KIGQGASGTVFTATDVALGQEVAIKQINLQKQPKK----ELIINEILVMKELKN-PNIVNFLDSYLVGDELFV--VMEYLAGGSLTDVVTETC-MDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDF-------GFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYL---NENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAK 504
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404])

HSP 1 Score: 95.5153 bits (236), Expect = 5.896e-22
Identity = 61/187 (32.62%), Postives = 100/187 (53.48%), Query Frame = 3 
Query: 1689 LENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLN 2249
            +E + GGS    LK   PL    I     +IL+GL +LH  + IHR++  +N+L+    +VKL  F  +  L   +TQ     F+G    +  ++APEV+ +  Y  +ADIWS G+  +E+  G+PP   ++D   + ++  I ++    L  +     K FVE CL+ DP+ R T +EL ++KF+ 
Sbjct:    1 MEYLGGGSALDLLKPG-PLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQL--TDTQIKRNTFVG----TPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP---NSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFIT 177
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Match: nsy-1 (Mitogen-activated protein kinase kinase kinase nsy-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21029])

HSP 1 Score: 104.76 bits (260), Expect = 1.312e-22
Identity = 60/190 (31.58%), Postives = 111/190 (58.42%), Query Frame = 3 
Query: 1689 LENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQ--YGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            +E++ GGS+++ L+  W P+  + +  +  QIL+GLK+LH  KI+HR++   N+LV+    V K+  F T K L G    +  + F G  +    Y+APEV++  Q  YGA ADIWSFG  +VE+  G+PP+ +  + +A      + ++ +  +  +I  + ++F++ C  P+  +R + ++L ++ F+
Sbjct:  729 MEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVT--ETFTGTLQ----YMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKT-HPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI 911
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Match: nsy-1 (Mitogen-activated protein kinase kinase kinase nsy-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21029])

HSP 1 Score: 104.76 bits (260), Expect = 1.388e-22
Identity = 60/190 (31.58%), Postives = 111/190 (58.42%), Query Frame = 3 
Query: 1689 LENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQ--YGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            +E++ GGS+++ L+  W P+  + +  +  QIL+GLK+LH  KI+HR++   N+LV+    V K+  F T K L G    +  + F G  +    Y+APEV++  Q  YGA ADIWSFG  +VE+  G+PP+ +  + +A      + ++ +  +  +I  + ++F++ C  P+  +R + ++L ++ F+
Sbjct:  743 MEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVT--ETFTGTLQ----YMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKT-HPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI 925
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3])

HSP 1 Score: 92.8189 bits (229), Expect = 1.486e-20
Identity = 57/190 (30.00%), Postives = 103/190 (54.21%), Query Frame = 3 
Query: 1677 LYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            L+ +++ +EGG++T  +     L    I     + L+ L FLH + I+HR++ + N+L+  N  VKL          G+  Q            +  +++PE++N+KQY  + DIWS G++ +E+I+G+PPY + T  +AI +I +  +   K   +++ S+  +F++ CL  DP +RA   EL  + FL
Sbjct:   70 LWVVMDYLEGGNLTDVVVKT-ELDEGQIAAVLQECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDM-------GFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDGEPPYLRETPLKAIYLIAQNGKPEIK-QRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPFL 250
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Match: aak-1 (5'-AMP-activated protein kinase catalytic subunit alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:P45894])

HSP 1 Score: 93.2041 bits (230), Expect = 1.956e-19
Identity = 63/261 (24.14%), Postives = 122/261 (46.74%), Query Frame = 3 
Query: 1476 LDEGDFSELFKAKWGAKFEDVLIKKYEKSS-KNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQY-GAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            + +G F  + +        DV IK   +   K LG      NE+   Q   + P   +L R+      ++ ++E + GG + +++     L   + +++  QI+ G+ + H + I+HR+L   N+L+D N+N+K+  F  S Y+        D + +     S  Y APE+++ K Y G + D+WS G+IL  ++ G  P+    D++ +  +    +SG   +   +  Q    +   L  DP +RA ++ +  + +  I
Sbjct:   30 IGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQ-KLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYM-------TDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLCGTLPF----DDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTMLQVDPVKRADVKRIVNHSWFRI 278
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Match: aak-1 (5'-AMP-activated protein kinase catalytic subunit alpha-1 [Source:UniProtKB/Swiss-Prot;Acc:P45894])

HSP 1 Score: 93.2041 bits (230), Expect = 1.956e-19
Identity = 63/261 (24.14%), Postives = 122/261 (46.74%), Query Frame = 3 
Query: 1476 LDEGDFSELFKAKWGAKFEDVLIKKYEKSS-KNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQY-GAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            + +G F  + +        DV IK   +   K LG      NE+   Q   + P   +L R+      ++ ++E + GG + +++     L   + +++  QI+ G+ + H + I+HR+L   N+L+D N+N+K+  F  S Y+        D + +     S  Y APE+++ K Y G + D+WS G+IL  ++ G  P+    D++ +  +    +SG   +   +  Q    +   L  DP +RA ++ +  + +  I
Sbjct:   30 IGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQ-KLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYM-------TDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLCGTLPF----DDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTMLQVDPVKRADVKRIVNHSWFRI 278
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Match: Ask1 (gene:FBgn0014006 transcript:FBtr0083819)

HSP 1 Score: 103.605 bits (257), Expect = 3.164e-22
Identity = 80/266 (30.08%), Postives = 131/266 (49.25%), Query Frame = 3 
Query: 1476 LDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRI---CKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRN-VKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            L +G +  ++ A+   K   V I   E   KN  D Q +  E+  +    SQ R   ++R    C +  F    +E + GGS++  L+  W PL +++  +  +S QIL+GLK+LH   I+HR++   N+LV+     VK+  F TSK L         + F G  +    Y+APEV+++  + YG  ADIWSFG   VE+  GKPP+ +        + K      +  + E++ +  K+F+  C      +R +  +L E+ FL
Sbjct:  424 LGKGTYGTVYAAR--DKQTQVRIAIKEVPEKNSQDVQPLHEEIKLH----SQLRHRNIVRYLGSCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRL--ARINPMTETFTGTLQ----YMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIE-LGSAHAAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQLLEDPFL 676
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Match: Ask1 (gene:FBgn0014006 transcript:FBtr0300256)

HSP 1 Score: 103.605 bits (257), Expect = 3.782e-22
Identity = 80/266 (30.08%), Postives = 131/266 (49.25%), Query Frame = 3 
Query: 1476 LDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRI---CKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRN-VKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            L +G +  ++ A+   K   V I   E   KN  D Q +  E+  +    SQ R   ++R    C +  F    +E + GGS++  L+  W PL +++  +  +S QIL+GLK+LH   I+HR++   N+LV+     VK+  F TSK L         + F G  +    Y+APEV+++  + YG  ADIWSFG   VE+  GKPP+ +        + K      +  + E++ +  K+F+  C      +R +  +L E+ FL
Sbjct:  591 LGKGTYGTVYAAR--DKQTQVRIAIKEVPEKNSQDVQPLHEEIKLH----SQLRHRNIVRYLGSCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRL--ARINPMTETFTGTLQ----YMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIE-LGSAHAAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQLLEDPFL 843
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Match: Pak3 (gene:FBgn0044826 transcript:FBtr0330047)

HSP 1 Score: 98.5969 bits (244), Expect = 4.531e-21
Identity = 62/192 (32.29%), Postives = 101/192 (52.60%), Query Frame = 3 
Query: 1677 LYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLN 2249
            L+ ++E M+GG +T  + +   +    I     + L  + FLH   IIHR++ + N+L+  + +VK+  F     + G E +        QT   + Y +APEVV RK+YG + DIWS G++ +E+I G+PPY   T   A+ +I        K   +K+   L+ F++ CL  +   RAT +EL  + FLN
Sbjct:  365 LWVVMEYMDGGPLTDVVTETV-MKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGDEKR--------QTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSW-DKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLN 546
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Match: Pak3 (gene:FBgn0044826 transcript:FBtr0083312)

HSP 1 Score: 98.5969 bits (244), Expect = 4.635e-21
Identity = 62/192 (32.29%), Postives = 101/192 (52.60%), Query Frame = 3 
Query: 1677 LYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLN 2249
            L+ ++E M+GG +T  + +   +    I     + L  + FLH   IIHR++ + N+L+  + +VK+  F     + G E +        QT   + Y +APEVV RK+YG + DIWS G++ +E+I G+PPY   T   A+ +I        K   +K+   L+ F++ CL  +   RAT +EL  + FLN
Sbjct:  365 LWVVMEYMDGGPLTDVVTETV-MKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGDEKR--------QTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSW-DKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLN 546
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Match: Pak3 (gene:FBgn0044826 transcript:FBtr0305003)

HSP 1 Score: 98.5969 bits (244), Expect = 4.635e-21
Identity = 62/192 (32.29%), Postives = 101/192 (52.60%), Query Frame = 3 
Query: 1677 LYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLN 2249
            L+ ++E M+GG +T  + +   +    I     + L  + FLH   IIHR++ + N+L+  + +VK+  F     + G E +        QT   + Y +APEVV RK+YG + DIWS G++ +E+I G+PPY   T   A+ +I        K   +K+   L+ F++ CL  +   RAT +EL  + FLN
Sbjct:  365 LWVVMEYMDGGPLTDVVTETV-MKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGDEKR--------QTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSW-DKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLN 546
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:ZFIN;Acc:ZDB-GENE-030827-3])

HSP 1 Score: 115.546 bits (288), Expect = 8.981e-26
Identity = 68/211 (32.23%), Postives = 118/211 (55.92%), Query Frame = 3 
Query: 1638 FVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
             VQ +    +  F+   +E + GGS++  L+  W PL N++  I  ++ QIL GLK+LH N+I+HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + + + S+ K F+  C  PDP  RAT  +L  ++FL +
Sbjct:  726 IVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILDGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKI-HPEIPDSMSSEAKAFILRCFEPDPDSRATANDLLTHEFLTV 929
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:ZFIN;Acc:ZDB-GENE-030827-3])

HSP 1 Score: 115.546 bits (288), Expect = 9.489e-26
Identity = 68/211 (32.23%), Postives = 118/211 (55.92%), Query Frame = 3 
Query: 1638 FVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
             VQ +    +  F+   +E + GGS++  L+  W PL N++  I  ++ QIL GLK+LH N+I+HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + + + S+ K F+  C  PDP  RAT  +L  ++FL +
Sbjct:  722 IVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILDGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKI-HPEIPDSMSSEAKAFILRCFEPDPDSRATANDLLTHEFLTV 925
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:ZFIN;Acc:ZDB-GENE-030827-3])

HSP 1 Score: 115.546 bits (288), Expect = 9.508e-26
Identity = 68/211 (32.23%), Postives = 118/211 (55.92%), Query Frame = 3 
Query: 1638 FVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
             VQ +    +  F+   +E + GGS++  L+  W PL N++  I  ++ QIL GLK+LH N+I+HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + + + S+ K F+  C  PDP  RAT  +L  ++FL +
Sbjct:  718 IVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILDGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKI-HPEIPDSMSSEAKAFILRCFEPDPDSRATANDLLTHEFLTV 921
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:ZFIN;Acc:ZDB-GENE-030827-3])

HSP 1 Score: 115.546 bits (288), Expect = 1.005e-25
Identity = 68/211 (32.23%), Postives = 118/211 (55.92%), Query Frame = 3 
Query: 1638 FVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
             VQ +    +  F+   +E + GGS++  L+  W PL N++  I  ++ QIL GLK+LH N+I+HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + + + S+ K F+  C  PDP  RAT  +L  ++FL +
Sbjct:  714 IVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILDGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKI-HPEIPDSMSSEAKAFILRCFEPDPDSRATANDLLTHEFLTV 917
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:ZFIN;Acc:ZDB-GENE-030827-3])

HSP 1 Score: 115.546 bits (288), Expect = 1.021e-25
Identity = 68/211 (32.23%), Postives = 118/211 (55.92%), Query Frame = 3 
Query: 1638 FVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
             VQ +    +  F+   +E + GGS++  L+  W PL N++  I  ++ QIL GLK+LH N+I+HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + + + S+ K F+  C  PDP  RAT  +L  ++FL +
Sbjct:  708 IVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILDGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKI-HPEIPDSMSSEAKAFILRCFEPDPDSRATANDLLTHEFLTV 911
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:549376])

HSP 1 Score: 125.176 bits (313), Expect = 1.308e-28
Identity = 93/329 (28.27%), Postives = 159/329 (48.33%), Query Frame = 3 
Query: 1344 FVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTK------LGQSTLFDGKLD------------EGDFSELFKAKWGAKFE------DVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            F+  H+N   D+   +F  E   +   +FC L K      +G +   +G+ D             GD   L +  +G  +        V I   E   K+   +Q +  E+  ++  K +   VQ +    ++ ++   +E + GGS++  L+  W PL    IK ++ QIL+GLK+LH N+I+HR++   N+LV+    V K+  F TSK L G       + F G  +    Y+APE++++  + YGA ADIWS G  ++E+  G+PP F    E    + K      +  + E + ++ + F+ +C  PDP +RAT+ +L  + FL
Sbjct:  592 FLYVHDNS--DDFQIYFSTE---DQCNRFCTLVKEIITDVVGNTVELEGEADGDTLEYEYDYDENGDRVVLGRGTYGVVYAGRDLSNQVRIAIKEIPEKDSRYSQPLHEEIALHKYLKHR-NIVQYLGSISEDGYIKIFMEQVPGGSLSVLLRSKWGPLKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAG--VNPCTETFTGTLQ----YMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGRPP-FHELGEPQAAMFKVGMFKIHPEIPESLSAEARAFILLCFEPDPAKRATVTDLLRDFFL 907
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:549376])

HSP 1 Score: 125.176 bits (313), Expect = 1.424e-28
Identity = 93/329 (28.27%), Postives = 159/329 (48.33%), Query Frame = 3 
Query: 1344 FVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTK------LGQSTLFDGKLD------------EGDFSELFKAKWGAKFE------DVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            F+  H+N   D+   +F  E   +   +FC L K      +G +   +G+ D             GD   L +  +G  +        V I   E   K+   +Q +  E+  ++  K +   VQ +    ++ ++   +E + GGS++  L+  W PL    IK ++ QIL+GLK+LH N+I+HR++   N+LV+    V K+  F TSK L G       + F G  +    Y+APE++++  + YGA ADIWS G  ++E+  G+PP F    E    + K      +  + E + ++ + F+ +C  PDP +RAT+ +L  + FL
Sbjct:  535 FLYVHDNS--DDFQIYFSTE---DQCNRFCTLVKEIITDVVGNTVELEGEADGDTLEYEYDYDENGDRVVLGRGTYGVVYAGRDLSNQVRIAIKEIPEKDSRYSQPLHEEIALHKYLKHR-NIVQYLGSISEDGYIKIFMEQVPGGSLSVLLRSKWGPLKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAG--VNPCTETFTGTLQ----YMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGRPP-FHELGEPQAAMFKVGMFKIHPEIPESLSAEARAFILLCFEPDPAKRATVTDLLRDFFL 850
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:549376])

HSP 1 Score: 125.176 bits (313), Expect = 1.427e-28
Identity = 93/329 (28.27%), Postives = 159/329 (48.33%), Query Frame = 3 
Query: 1344 FVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTK------LGQSTLFDGKLD------------EGDFSELFKAKWGAKFE------DVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            F+  H+N   D+   +F  E   +   +FC L K      +G +   +G+ D             GD   L +  +G  +        V I   E   K+   +Q +  E+  ++  K +   VQ +    ++ ++   +E + GGS++  L+  W PL    IK ++ QIL+GLK+LH N+I+HR++   N+LV+    V K+  F TSK L G       + F G  +    Y+APE++++  + YGA ADIWS G  ++E+  G+PP F    E    + K      +  + E + ++ + F+ +C  PDP +RAT+ +L  + FL
Sbjct:  584 FLYVHDNS--DDFQIYFSTE---DQCNRFCTLVKEIITDVVGNTVELEGEADGDTLEYEYDYDENGDRVVLGRGTYGVVYAGRDLSNQVRIAIKEIPEKDSRYSQPLHEEIALHKYLKHR-NIVQYLGSISEDGYIKIFMEQVPGGSLSVLLRSKWGPLKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAG--VNPCTETFTGTLQ----YMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGRPP-FHELGEPQAAMFKVGMFKIHPEIPESLSAEARAFILLCFEPDPAKRATVTDLLRDFFL 899
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:549376])

HSP 1 Score: 124.79 bits (312), Expect = 1.543e-28
Identity = 93/329 (28.27%), Postives = 159/329 (48.33%), Query Frame = 3 
Query: 1344 FVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTK------LGQSTLFDGKLD------------EGDFSELFKAKWGAKFE------DVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            F+  H+N   D+   +F  E   +   +FC L K      +G +   +G+ D             GD   L +  +G  +        V I   E   K+   +Q +  E+  ++  K +   VQ +    ++ ++   +E + GGS++  L+  W PL    IK ++ QIL+GLK+LH N+I+HR++   N+LV+    V K+  F TSK L G       + F G  +    Y+APE++++  + YGA ADIWS G  ++E+  G+PP F    E    + K      +  + E + ++ + F+ +C  PDP +RAT+ +L  + FL
Sbjct:  592 FLYVHDNS--DDFQIYFSTE---DQCNRFCTLVKEIITDVVGNTVELEGEADGDTLEYEYDYDENGDRVVLGRGTYGVVYAGRDLSNQVRIAIKEIPEKDSRYSQPLHEEIALHKYLKHR-NIVQYLGSISEDGYIKIFMEQVPGGSLSVLLRSKWGPLKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAG--VNPCTETFTGTLQ----YMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGRPP-FHELGEPQAAMFKVGMFKIHPEIPESLSAEARAFILLCFEPDPAKRATVTDLLRDFFL 907
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:549376])

HSP 1 Score: 124.79 bits (312), Expect = 1.616e-28
Identity = 93/329 (28.27%), Postives = 159/329 (48.33%), Query Frame = 3 
Query: 1344 FVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTK------LGQSTLFDGKLD------------EGDFSELFKAKWGAKFE------DVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            F+  H+N   D+   +F  E   +   +FC L K      +G +   +G+ D             GD   L +  +G  +        V I   E   K+   +Q +  E+  ++  K +   VQ +    ++ ++   +E + GGS++  L+  W PL    IK ++ QIL+GLK+LH N+I+HR++   N+LV+    V K+  F TSK L G       + F G  +    Y+APE++++  + YGA ADIWS G  ++E+  G+PP F    E    + K      +  + E + ++ + F+ +C  PDP +RAT+ +L  + FL
Sbjct:  574 FLYVHDNS--DDFQIYFSTE---DQCNRFCTLVKEIITDVVGNTVELEGEADGDTLEYEYDYDENGDRVVLGRGTYGVVYAGRDLSNQVRIAIKEIPEKDSRYSQPLHEEIALHKYLKHR-NIVQYLGSISEDGYIKIFMEQVPGGSLSVLLRSKWGPLKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAG--VNPCTETFTGTLQ----YMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGRPP-FHELGEPQAAMFKVGMFKIHPEIPESLSAEARAFILLCFEPDPAKRATVTDLLRDFFL 889
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Match: Map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:MGI Symbol;Acc:MGI:2448588])

HSP 1 Score: 117.472 bits (293), Expect = 2.768e-26
Identity = 89/329 (27.05%), Postives = 158/329 (48.02%), Query Frame = 3 
Query: 1344 FVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTK------LGQSTLFDGKLD------------EGDFSELFKAKWGAKFE------DVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRN-VKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            F+  H+N   D+   +F  E   +   +FC L K      +G +   +G+ D             G+   L K  +G  +        V I   E   +++  +Q +  E+  ++  K +   VQ +    +  ++   +E + GGS++  L+  W P+    IK ++ QIL+GLK+LH N+I+HR++   N+LV+     VK+  F TSK L G    +  + F G    + +Y+APE++++  + YGA ADIWS G  ++E+   +PP F    E    + K      +  + E + ++ + F+  C  PDP++R T  +L +  FL
Sbjct:  597 FLYVHDNS--DDFQIYFSTE---DQCNRFCSLVKEMLNNGVGSTVELEGEADGDTLEYEYDHDANGERVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQPLHEEIALHKYLKHR-NIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCT--ETFTG----TLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPP-FHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFL 912
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Match: Map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:MGI Symbol;Acc:MGI:1346876])

HSP 1 Score: 112.849 bits (281), Expect = 6.338e-25
Identity = 82/281 (29.18%), Postives = 147/281 (52.31%), Query Frame = 3 
Query: 1449 GQSTLFDGKLDE-GDFSELFKAKWGAKFE------DVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            G S  +D + DE GD   L K  +G  +        V I   E   ++   +Q +  E+  ++  K +   VQ +    +  F+   +E + GGS++  L+  W PL +++  I  ++ QIL+GLK+LH N+I+HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + E + ++ K F+  C  PDP +RA   +L  ++FL +
Sbjct:  667 GDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHK-NIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKV-HPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFLKV 939
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Match: Map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:MGI Symbol;Acc:MGI:1346876])

HSP 1 Score: 112.849 bits (281), Expect = 6.468e-25
Identity = 82/281 (29.18%), Postives = 147/281 (52.31%), Query Frame = 3 
Query: 1449 GQSTLFDGKLDE-GDFSELFKAKWGAKFE------DVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            G S  +D + DE GD   L K  +G  +        V I   E   ++   +Q +  E+  ++  K +   VQ +    +  F+   +E + GGS++  L+  W PL +++  I  ++ QIL+GLK+LH N+I+HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + E + ++ K F+  C  PDP +RA   +L  ++FL +
Sbjct:  675 GDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHK-NIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKV-HPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFLKV 947
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Match: Pak1 (p21 (RAC1) activated kinase 1 [Source:MGI Symbol;Acc:MGI:1339975])

HSP 1 Score: 105.145 bits (261), Expect = 4.703e-23
Identity = 82/270 (30.37%), Postives = 142/270 (52.59%), Query Frame = 3 
Query: 1473 KLDEGDFSELFKAKWGAKFEDVLIKKY---EKSSKNLGDNQDILNELITYQITKSQPRFVQLIR--ICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFL--SEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 2258
            K+ +G    ++ A   A  ++V IK+    ++  K L     I+NE++  +  K+ P  V  +   +  DE  L+ ++E + GGS+T  + +   +    I     + LQ L+FLH N++IHR++ + NIL+  + +VKL  F       G+  Q   ++    T   + Y +APEVV RK YG + DIWS G++ +E+I G+PPY    +E  +  +  I  +G   L   EK+ +  + F+  CL  D ++R + +EL +++FL I K
Sbjct:  274 KIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKEL-----IINEILVMRENKN-PNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETC-MDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDF-------GFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYL---NENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAK 524
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Match: Pak1 (p21 (RAC1) activated kinase 1 [Source:MGI Symbol;Acc:MGI:1339975])

HSP 1 Score: 105.145 bits (261), Expect = 4.703e-23
Identity = 82/270 (30.37%), Postives = 142/270 (52.59%), Query Frame = 3 
Query: 1473 KLDEGDFSELFKAKWGAKFEDVLIKKY---EKSSKNLGDNQDILNELITYQITKSQPRFVQLIR--ICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFL--SEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 2258
            K+ +G    ++ A   A  ++V IK+    ++  K L     I+NE++  +  K+ P  V  +   +  DE  L+ ++E + GGS+T  + +   +    I     + LQ L+FLH N++IHR++ + NIL+  + +VKL  F       G+  Q   ++    T   + Y +APEVV RK YG + DIWS G++ +E+I G+PPY    +E  +  +  I  +G   L   EK+ +  + F+  CL  D ++R + +EL +++FL I K
Sbjct:  274 KIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKEL-----IINEILVMRENKN-PNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETC-MDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDF-------GFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYL---NENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAK 524
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Match: sp|Q6ZN16|M3K15_HUMAN (Mitogen-activated protein kinase kinase kinase 15 OS=Homo sapiens OX=9606 GN=MAP3K15 PE=1 SV=2)

HSP 1 Score: 117.472 bits (293), Expect = 1.840e-25
Identity = 69/207 (33.33%), Postives = 110/207 (53.14%), Query Frame = 3 
Query: 1638 FVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRN-VKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
             VQ +    +  ++   +E + GGS++  L+  W P+    IK ++ QIL+GLK+LH N+I+HR++   N+LV+     VK+  F TSK L G       + F G  +    Y+APE++++  + YGA ADIWS G  ++E+   KPP F    E    + K      +  + E + ++ + F+  C  PDP +RAT  EL    FL
Sbjct:  709 IVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAG--VNPCTETFTGTLQ----YMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPP-FHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFL 908
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Match: sp|A2AQW0|M3K15_MOUSE (Mitogen-activated protein kinase kinase kinase 15 OS=Mus musculus OX=10090 GN=Map3k15 PE=1 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 1.936e-25
Identity = 89/329 (27.05%), Postives = 158/329 (48.02%), Query Frame = 3 
Query: 1344 FVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTK------LGQSTLFDGKLD------------EGDFSELFKAKWGAKFE------DVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRN-VKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            F+  H+N   D+   +F  E   +   +FC L K      +G +   +G+ D             G+   L K  +G  +        V I   E   +++  +Q +  E+  ++  K +   VQ +    +  ++   +E + GGS++  L+  W P+    IK ++ QIL+GLK+LH N+I+HR++   N+LV+     VK+  F TSK L G    +  + F G    + +Y+APE++++  + YGA ADIWS G  ++E+   +PP F    E    + K      +  + E + ++ + F+  C  PDP++R T  +L +  FL
Sbjct:  597 FLYVHDNS--DDFQIYFSTE---DQCNRFCSLVKEMLNNGVGSTVELEGEADGDTLEYEYDHDANGERVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQPLHEEIALHKYLKHR-NIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCT--ETFTG----TLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPP-FHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFL 912
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Match: sp|O35099|M3K5_MOUSE (Mitogen-activated protein kinase kinase kinase 5 OS=Mus musculus OX=10090 GN=Map3k5 PE=1 SV=3)

HSP 1 Score: 112.849 bits (281), Expect = 4.524e-24
Identity = 82/281 (29.18%), Postives = 147/281 (52.31%), Query Frame = 3 
Query: 1449 GQSTLFDGKLDE-GDFSELFKAKWGAKFE------DVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            G S  +D + DE GD   L K  +G  +        V I   E   ++   +Q +  E+  ++  K +   VQ +    +  F+   +E + GGS++  L+  W PL +++  I  ++ QIL+GLK+LH N+I+HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + E + ++ K F+  C  PDP +RA   +L  ++FL +
Sbjct:  675 GDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHK-NIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKV-HPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFLKV 947
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Match: sp|Q54R82|MKKA_DICDI (Mitogen-activated protein kinase kinase kinase A OS=Dictyostelium discoideum OX=44689 GN=mkkA PE=1 SV=2)

HSP 1 Score: 112.464 bits (280), Expect = 4.987e-24
Identity = 65/203 (32.02%), Postives = 104/203 (51.23%), Query Frame = 3 
Query: 1638 FVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
             V+ +    D+ FL   LE + GGSI++ L      + + IK ++ QILQGL FLH N IIHR++  +NIL+D    VKL  F  SK   G  +Q          + +  ++APEV+ +  +G  +DIWS G ++VE+   +PP+   T+  A+        S    +   +  +   F+ +C   DPKER    +L ++ F+
Sbjct:  234 IVRYLGTSLDQSFLSVFLEYIPGGSISSLLGKFGAFSENVIKVYTKQILQGLSFLHANSIIHRDIKGANILIDTKGIVKLSDFGCSKSFSGIVSQ------FKSMQGTPYWMAPEVIKQTGHGRSSDIWSLGCVIVEMATAQPPWSNITELAAVMYHIASSNS-IPNIPSHMSQEAFDFLNLCFKRDPKERPDANQLLKHPFI 429
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Match: sp|Q99683|M3K5_HUMAN (Mitogen-activated protein kinase kinase kinase 5 OS=Homo sapiens OX=9606 GN=MAP3K5 PE=1 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 5.269e-24
Identity = 66/210 (31.43%), Postives = 120/210 (57.14%), Query Frame = 3 
Query: 1641 VQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            VQ +    +  F+   +E + GGS++  L+  W PL +++  I  ++ QIL+GLK+LH N+I+HR++   N+L++    V K+  F TSK L G    +  + F G    + +Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + E + ++ K F+  C  PDP +RA   +L  ++FL +
Sbjct:  738 VQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTG----TLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKV-HPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKV 940
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Match: A0BC86 (Protein kinase domain-containing protein OS=Paramecium tetraurelia OX=5888 GN=GSPATT00004247001 PE=3 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 8.251e-29
Identity = 71/205 (34.63%), Postives = 111/205 (54.15%), Query Frame = 3 
Query: 1632 PRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            P  V+ +   +  +F+   LE + GGS+ + L+         IK +  QIL GL +LH   +IHR++   NIL+D +   KL  F +SK L       F  + +G    +  Y+APEV+N++QYG +ADIWS G  ++E+  G PP+ +  D  AI +             + I ++ +HFV +CL  DPK+RAT++EL  + FL
Sbjct:  122 PNIVRYLGCEQKNQFINIFLEYVSGGSVQSMLERFGCFKESLIKTYLRQILLGLSYLHAKNVIHRDIKGGNILIDNSGKCKLADFGSSKQLS-----DFAHDTLGSICGTPNYMAPEVINQEQYGKKADIWSLGCTIIEMATGLPPFSELKDAIAIMVRIGKSTKPPSIPPQLISAESRHFVSLCLQIDPKKRATVDELLNHPFL 321
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Match: A0EFT4 (Protein kinase domain-containing protein OS=Paramecium tetraurelia OX=5888 GN=GSPATT00026498001 PE=3 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 1.221e-26
Identity = 68/197 (34.52%), Postives = 112/197 (56.85%), Query Frame = 3 
Query: 1662 KDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKF--LSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            KD   +Y   E M  GSI+  L +  P+T   IK ++ QIL GL++LH   I+H +L +SNIL+D + ++K+  F  S+++     QS         + S  ++APEVV ++Q    ADIWSFG +++E++ GK P+F+  D + +           +   + E +  +LK F+++C   DP +RATI+EL ++ FL
Sbjct:  118 KDSLLIYQ--EYMPMGSISQLLNEFGPMTESTIKTYTHQILNGLEYLHNKGILHLDLKSSNILLDSSGDIKISDFGCSRHIKQNLCQSI-------LQGSVPWMAPEVVRQEQIDTPADIWSFGCLILEMLTGKHPWFEQLDFDNVASTLLAIAFNQESPRIPEGVSEELKRFLQMCFSQDPLQRATIQELRQSAFL 305
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Match: A0A060SKW9 (Protein kinase domain-containing protein OS=Pycnoporus cinnabarinus OX=5643 GN=BN946_scf184757.g5 PE=3 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 1.566e-26
Identity = 86/263 (32.70%), Postives = 145/263 (55.13%), Query Frame = 3 
Query: 1473 KLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIR--ICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFL--SEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            K+ +G    ++ AK  A  + V IK+ + S  N    + I+NE++  + ++  P  V  +   + K+   L+ ++E MEGG++T  +++N  L  D I     +  +GL  LH   IIHR++ + N+L+D   +VK+  F       G+  +  D++    T   + Y +APEVV +K+YGA+ DIWS G++ +E+I  +PPY    DEE ++ +  I  +G   L   E +  +LK F+ +CL  D K RAT EEL +++FL
Sbjct:   28 KVGQGASGHVYVAKTHATGKKVAIKEMDLS--NQPRKELIVNEILVMKESQ-HPNIVNFLDAYLVKNNE-LWVVMEYMEGGALTDIIENN-TLEEDQISSICLETCKGLNHLHNQSIIHRDIKSDNVLLDAQGHVKITDF-------GFCAKLTDQKSKRATMVGTPYWMAPEVVKQKEYGAKVDIWSLGIMAIEMIENEPPYL---DEEPLKALYLIATNGTPTLKKPETLSRELKSFLSVCLCVDVKSRATAEELLQHEFL 275
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Match: A0A1D2N3M8 (Mitogen-activated protein kinase kinase kinase 15 OS=Orchesella cincta OX=48709 GN=Ocin01_06825 PE=4 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 1.614e-26
Identity = 96/314 (30.57%), Postives = 155/314 (49.36%), Query Frame = 3 
Query: 1356 HNNKYLD------EDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQ--YGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQL----KHFVEICLHPDPKERATIEELFENKFLN 2249
             NN++ D      E+   ++YE D E T K                L +G +  ++ A+  +    + +K  E   KNLG+ Q +  E+  +   + +   VQ +    ++ +   ++E + GGS++  L+  W PL   +  I  ++ QIL+GLK+LH  KI+HR++   N+LV+    V K+  F TSK L G       K F G  +    Y+APEV+++ Q  YGA ADIWS G  +VE+  GKPP+ +            + + G+  +  +I S++    K F+  C  PDP +RAT  EL E+ FL 
Sbjct:  590 QNNRFTDLDAALSEEQIRYEYEFD-EQTKKVV--------------LGKGTYGTVYAARDLSTQVRIAVK--EIPEKNLGEVQPLHEEIRLHSQLRHR-NIVQYLGSVSEDSYFKILMEQVPGGSLSALLRSKWGPLKGSEPTIAYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAG--ISPLTKTFAGTLQ----YMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIE-----LGSPEAAMFKVGFYKMHPQIPSEMSERAKKFILKCFEPDPDKRATAAELLEDPFLT 874
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Match: A0A1B6HXA0 (Protein kinase domain-containing protein (Fragment) OS=Homalodisca liturata OX=320908 GN=g.40373 PE=4 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 1.973e-26
Identity = 99/323 (30.65%), Postives = 158/323 (48.92%), Query Frame = 3 
Query: 1317 MKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGY--ETQSFDKEFMGQTEKSSRYLAPEVVNRKQ--YGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQL----KHFVEICLHPDPKERATIEELFENKFLN 2249
            ++M  D E  V   +   L ED   F+YE+D+            G+  +    L +G +  +++A+       V I   E   +NLGD Q +  E+  +   + +   VQ +    ++ +    +E + GGS++  L+  W PL  ++  I  ++ QIL+GLK+LH  KI+HR++   N+LV+    V K+  F TSK L G    T++F            +Y+APEV+++ Q  YGA ADIWS G  +VE+  GKPP+ +            + + GY  +  +I S+L    K F+  C  PDP  RA   EL E+ FL 
Sbjct:  380 LEMTVDQEGMVTGLDQD-LTEDQIKFEYELDD-----------TGKRII----LGKGTYGVVYQAR--DLNTQVRIAVKEIPERNLGDVQPLHEEIKLHSQLRHR-NIVQYLGSVSEDGYFKIFMEQVPGGSLSALLRSKWGPLKENESTISYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLCPSTETFSGTL--------QYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIE-----LGSPQAAVFKVGYYKVHPEIPSELSEKAKSFILRCFEPDPAHRALAAELLEDSFLT 670
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Match: map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:ZFIN;Acc:ZDB-GENE-091204-246])

HSP 1 Score: 117.087 bits (292), Expect = 2.513e-26
Identity = 72/222 (32.43%), Postives = 118/222 (53.15%), Query Frame = 3 
Query: 1593 LNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            L+E I       Q   VQ +    ++ ++   +E + GGS++  L+  W PL    I  ++ QIL+GL++LH N+I+HR++   N+LV+    V K+  F TSK L G       + F G  +    Y+APE++++  + YGA ADIWS G  ++E+  GKPP F    E    + K      +  + E + ++ K F+  C  PDP +RAT  +L ++ F+
Sbjct:  683 LHEEIALHKYLKQRNIVQYLGSVSEDGYIKIFMEQVPGGSLSALLRSKWGPLKEATIIFYTRQILEGLRYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAG--VNPCTETFTGTLQ----YMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGKPP-FHELGEPQAAMFKVGMFKIHPEIPESLSTEAKSFILRCFEPDPNKRATAGDLLKDLFV 897
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:103033000])

HSP 1 Score: 114.775 bits (286), Expect = 1.226e-25
Identity = 69/210 (32.86%), Postives = 118/210 (56.19%), Query Frame = 3 
Query: 1641 VQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            VQ +    +  F+   +E + GGS++  L+  W PL N++  I  ++ QIL+GLK+LH N+I HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + + + S+ K F+  C  PDP  RAT  EL  ++FL +
Sbjct:  715 VQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILEGLKYLHDNQIAHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKI-HPEIPDSMSSEAKAFILRCFEPDPDLRATANELLTHEFLTV 917
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:103033000])

HSP 1 Score: 114.775 bits (286), Expect = 1.326e-25
Identity = 69/210 (32.86%), Postives = 118/210 (56.19%), Query Frame = 3 
Query: 1641 VQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            VQ +    +  F+   +E + GGS++  L+  W PL N++  I  ++ QIL+GLK+LH N+I HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + + + S+ K F+  C  PDP  RAT  EL  ++FL +
Sbjct:  707 VQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILEGLKYLHDNQIAHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKI-HPEIPDSMSSEAKAFILRCFEPDPDLRATANELLTHEFLTV 909
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:103033000])

HSP 1 Score: 114.775 bits (286), Expect = 1.387e-25
Identity = 69/210 (32.86%), Postives = 118/210 (56.19%), Query Frame = 3 
Query: 1641 VQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            VQ +    +  F+   +E + GGS++  L+  W PL N++  I  ++ QIL+GLK+LH N+I HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  GKPP+++  + +A      + +  +  + + + S+ K F+  C  PDP  RAT  EL  ++FL +
Sbjct:  704 VQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILEGLKYLHDNQIAHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKI-HPEIPDSMSSEAKAFILRCFEPDPDLRATANELLTHEFLTV 906
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Match: pak1 (p21 protein (Cdc42/Rac)-activated kinase 1 [Source:ZFIN;Acc:ZDB-GENE-030826-29])

HSP 1 Score: 104.76 bits (260), Expect = 3.747e-23
Identity = 81/268 (30.22%), Postives = 141/268 (52.61%), Query Frame = 3 
Query: 1473 KLDEGDFSELFKAKWGAKFEDVLIKKY---EKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFL--SEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 2258
            K+ +G    ++ A   A  ++V IK+    ++  K L     I+NE++  +  +++P  V       DE  L+ ++E + GGS+T  + +   +    I     + LQ L+FLH N++IHR++ + NIL+  + +VKL  F       G+  Q   ++    T   + Y +APEVV RK YG + DIWS G++ +E+I G+PPY    +E  +  +  I  +G   L   EK+ S  + F+  CL  D ++R + +EL +++FL + K
Sbjct:  236 KIGQGASGTVYTAIDIATGQEVAIKQMNLQQQPKKEL-----IINEILVMR--ENKPYLV------GDE--LWVVMEYLAGGSLTDVVTETC-MDEAQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDF-------GFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYL---NENPLRALYLIATNGTPELQNPEKLSSVFRDFLNRCLEMDVEKRGSAKELLQHQFLKVAK 477
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96])

HSP 1 Score: 102.064 bits (253), Expect = 1.184e-22
Identity = 57/148 (38.51%), Postives = 84/148 (56.76%), Query Frame = 3 
Query: 1635 RFVQLIRICKD--ERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPY 2072
            R VQ     +D  ++ L   +E M GGSI   L+    LT +  +K++ QIL+G+ FLH N I+HR++  +NIL D   NVKL  F  SK L    +Q      M     +  +++PEV+N + YG +ADIWS G  +VE++  KPP+
Sbjct:  420 RIVQYFGCLRDPQQKTLSIFMEYMPGGSIKDQLRAYGALTENVTRKYTRQILEGVSFLHGNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICSQG---TAMRSVTGTPYWMSPEVINGEGYGRKADIWSVGCTVVEMLTEKPPW 564
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Match: plk3 (polo-like kinase 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-6134])

HSP 1 Score: 99.3673 bits (246), Expect = 8.122e-22
Identity = 63/204 (30.88%), Postives = 99/204 (48.53%), Query Frame = 3 
Query: 1638 FVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLN 2249
             VQ I   KDE F+Y ILE   G S+   L+    LT  ++K +  Q++ GL++LH   ++HR+L   N  V  +  VK+     +  L   E     K  +  T     YLAPEV+N++ +G +ADIWS G  +  ++ G+PP F ++D   +        SG       +    +  +   L PDP  RA++ +L  + FL 
Sbjct:   87 IVQFISSFKDENFIYIILELCNGQSLAHMLRSRKVLTETEVKYYLRQLISGLRYLHQCGVVHRDLKLGNFFVTDSMEVKIGDLGLATTL---EPPEMRKRTVCGTPN---YLAPEVLNKRGHGPEADIWSLGCAVFTMLAGRPP-FSTSD---LANTYACIRSGRFNFPPSLSHAARDLLTSALTPDPDLRASLLDLQSHPFLT 280
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Match: pak4 (p21 protein (Cdc42/Rac)-activated kinase 4 [Source:ZFIN;Acc:ZDB-GENE-040704-69])

HSP 1 Score: 91.2781 bits (225), Expect = 3.038e-19
Identity = 55/191 (28.80%), Postives = 104/191 (54.45%), Query Frame = 3 
Query: 1677 LYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLN 2249
            L+ ++E +EGG++T  +     +  + I      +L+ L +LH   +IHR++ + +IL+  +  +KL  F     +    T+   K  +G    +  ++APEV++R  YG + D+WS G++++E+++G+PPYF     +A+  I++      K + +K    L+ F++  L  DP  RAT  EL ++ FL 
Sbjct:  489 LWVVMEFLEGGALTDIVTHTR-MNEEQIATVCVSVLRALAYLHGQGVIHRDIKSDSILLTADGRIKLSDFGFCAQVSKEVTRR--KSLVG----TPYWMAPEVISRLPYGPEVDVWSLGIMVIEMVDGEPPYFNEPPLQAMRRIRDNVPPKMKNI-QKASPLLRGFLDQMLVRDPALRATALELLQHPFLQ 671
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006670.1 (pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene:ENSPMAG00000006016.1 transcript:ENSPMAT00000006670.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 89.3521 bits (220), Expect = 3.085e-19
Identity = 69/258 (26.74%), Postives = 120/258 (46.51%), Query Frame = 3 
Query: 1473 KLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKS--QPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTND--DIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIIN-GKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEI-CLHPDPKERATIEEL 2228
            +L  G F E+++  W  K   V IK  ++ +    D  D L E    Q+ K    P+ +QL  +C  E  +Y I E M  GS+  +L+     + D  ++   + Q+  G+ +L     IHR+L+  NILV  +   K+  F  ++ +       ++      ++   ++ APE  N  ++  ++D+WSFG++L EII  GK PY   T+      +    + GY+      C Q  + + + C + D + R T E L
Sbjct:  119 RLGAGQFGEVWQGLWN-KTTPVAIKTLKQGTM---DRDDFLREA---QLMKRLRHPKLIQLYAVCTQEEPIYIITELMSNGSLANYLQTPEGRSLDLVELVDMAAQVAAGMAYLEAQNYIHRDLAARNILVAEHNACKVADFGLARVIKMSNEDEYEARV--GSKFPIKWTAPEAANYNRFSIKSDVWSFGVLLHEIITYGKLPYPGQTN----AEVLAAVDRGYRMPCPPGCPQAFYDLMLECWNVDDQARPTFETL 363
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92])

HSP 1 Score: 88.1965 bits (217), Expect = 1.170e-18
Identity = 60/193 (31.09%), Postives = 102/193 (52.85%), Query Frame = 3 
Query: 1677 LYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNL--STSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLN 2249
            L+ I+E + GGS    +K   PL    I     +IL+GL +LH  + IHR++    +N+L+    +VKL  F  +  L   +TQ     F+G    +  ++APEV+ +  Y  +ADIWS G+  +E+  G+PP   +++   + ++  I ++    L        K FV+ CL+ DP+ R T +EL ++KF+ 
Sbjct:   97 LWIIMEYLGGGSALDLIKPG-PLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQL--TDTQIKRNTFVG----TPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPP---NSELHPMRVLFLIPKNNPPTLEGNYSKAFKEFVDSCLNKDPQFRPTAKELLKHKFIQ 279
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999])

HSP 1 Score: 108.997 bits (271), Expect = 8.178e-25
Identity = 87/283 (30.74%), Postives = 142/283 (50.18%), Query Frame = 3 
Query: 1407 DNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKY--EKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            D + + K+  L K+GQ          G    ++ A        V IK+   EK  K     + I+NE++  + +K  P  V  I     +  L+ I+E MEGGS+T  +  +  LT   I     + L GL+FLH   ++HR++ + NIL+    ++KL  F       G+  Q  +      T   + Y +APEVV+RK+YG + DIWS G++++E+I G+PPY   T   A+ +I        K   E + S LK F++ CL  +P++RA+  EL  ++++
Sbjct:  613 DGDPSTKYANLVKIGQ----------GASGGVYTAYEIGTNVSVAIKQMNLEKQPKK----ELIINEILVMKGSK-HPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVT-HCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDF-------GFCAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKE-PENLSSSLKKFLDWCLCVEPEDRASATELLHDEYI 871
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Match: SKM1 (Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473])

HSP 1 Score: 103.219 bits (256), Expect = 3.282e-23
Identity = 71/233 (30.47%), Postives = 118/233 (50.64%), Query Frame = 3 
Query: 1584 QDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFL---------KDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            Q I+NEL+    ++ +     L     D+  L+ I+E MEGG +T  L         + + PL  + +     +  QGLKFLH  KIIHR++ + NIL++    VK+  F       G+  +  +K     T   + Y +APE+VN+K Y  + D+WS G++L+E+I G+PPY  + D      +     S      E +  Q K F++ CL  + + RA++ +L   +FL++
Sbjct:  417 QLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDF-------GFCVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYL-NEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFLSM 641
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Match: CLA4 (Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242])

HSP 1 Score: 102.449 bits (254), Expect = 7.383e-23
Identity = 65/200 (32.50%), Postives = 107/200 (53.50%), Query Frame = 3 
Query: 1677 LYGILENMEGGSITTFLKDNW-------PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            L+ ++E MEGGS+T  ++++        PLT   I     +  QGLKFLH   IIHR++ + N+L+D    VK+  F       G+  +  DK     T   + Y +APEVV +++Y  + D+WS G++ +E++ G+PPY      +A+ +I        K   E +  ++K F+ +CL  D + RA+ EEL  + F N+
Sbjct:  636 LWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDF-------GFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKH-PESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFFNM 827
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Match: PKH2 (Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh1p; PKH2 has a paralog, PKH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005460])

HSP 1 Score: 95.9005 bits (237), Expect = 1.009e-20
Identity = 56/161 (34.78%), Postives = 86/161 (53.42%), Query Frame = 3 
Query: 1632 PRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHG---------YETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTD 2087
            P  V+L    +DE  LY +LE    G   + +K    L     + ++ QI+  + +LH N IIHR++   NIL+DG   +KL  F T+K L+          Y+  +  K F+G  E    Y++PE++N      + DIW+FG IL ++I GKPP FK+T+
Sbjct:  238 PSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAE----YVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPP-FKATN 393
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603])

HSP 1 Score: 90.5077 bits (223), Expect = 3.993e-19
Identity = 86/307 (28.01%), Postives = 142/307 (46.25%), Query Frame = 3 
Query: 1353 FHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTL-FDGK-------LDEGDFSELFKAK--WGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGA--QADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEK-ICSQLKHFVEICLHPDPKERATIEELFE 2234
            F   K LD +N         +   K   L K   S +   GK       L EG F+  F+ K   G  F    + K   S K+    + +L+E+  ++ + S P  VQ I   +D+  +Y +LE    GS+   LK    LT  +++ ++ QI   +K++H  ++IHR+L   NI  D N N+K+  F  +  L     + +     G    +  Y+APEV+  K  G   + DIWS G++L  ++ GKPP F++ D   I    + ++  + F  +K I  + K  +   L  DP ER ++ E+ +
Sbjct:   39 FKQTKRLDPNNDHHHQPAQKKKREKLSALCKTPPSLIKTRGKDYHRGHFLGEGGFARCFQIKDDSGEIFAAKTVAK--ASIKSEKTRKKLLSEIQIHK-SMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYT--ICG----TPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPP-FQARDVNTIYERIKCRD--FSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMD 333
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7])

HSP 1 Score: 105.145 bits (261), Expect = 4.068e-25
Identity = 55/146 (37.67%), Postives = 86/146 (58.90%), Query Frame = 3 
Query: 1635 RFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPY 2072
            R VQ   I  D+  +Y  +E + GGSI   +K +  L     +K+S QIL+G+ +LH N+I+HR++  +NIL D   NVKL  F  SK L    +++  +   G    +  ++APEV+N + YG +AD+WS G  +VE++  KPP+
Sbjct:   65 RIVQYYGIETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYGNVKLADFGASKRLQTIRSKTGFRSVHG----TPYWMAPEVINGEGYGRKADVWSVGCTVVEMLTTKPPW 206
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Match: EDO36150 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJF2])

HSP 1 Score: 106.686 bits (265), Expect = 1.051e-23
Identity = 73/266 (27.44%), Postives = 131/266 (49.25%), Query Frame = 3 
Query: 1476 LDEGDFSELFKAKWGAKFEDVLIKK--YEKSSKNLGDN--QDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDG-NRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXS-GYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIM 2255
            L  G FS  + A+       + +K+  + ++SK+  D   Q I++E+      K  P  ++ +   +        LE M GGSI+  L    P     + ++  QILQG+ +LH N+++HR++  +NILVD   +++++  F  +  L    T +   EF GQ   +  ++APEV+  + YG   D+WS G +L+E+  GKPP+        + +I +I  + G   + E +   ++  V  CL   P++R    +L ++    IM
Sbjct:  583 LGTGAFSSCYGARDVMTGSLMAVKQVSFCRNSKSEQDKVCQTIMDEIAILARLK-HPHLIKCLGATRHTGHFNIFLEWMAGGSISMLLSKYGPFEEAILIRYLRQILQGVSYLHENQVVHRDIKGANILVDSTGQDIRIADFGAAARLATQITGA--GEFQGQLLGTIAFMAPEVLRGESYGRSCDVWSVGCVLIEMATGKPPWNAHEHSNHLALIFKIACAIGPPDIPEHLNPGVRDVVLRCLESKPEDRPAAVDLLQHPLFTIM 845
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Match: EDO27976 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7S3])

HSP 1 Score: 100.138 bits (248), Expect = 2.633e-23
Identity = 52/164 (31.71%), Postives = 88/164 (53.66%), Query Frame = 3 
Query: 1584 QDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDG-NRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPY 2072
            Q I++E+      K  P  ++ +   +        LE M GGSI+  L    P     + ++  QILQG+ +LH N+++HR++  +NILVD   +++++  F  +  L    T +   EF GQ   +  ++APEV+  + YG   D+WS G +L+E+  GKPP+
Sbjct:   85 QTIMDEIAILARLK-HPHLIKCLGATRHTGHFNIFLEWMAGGSISMLLSKYGPFEEAILIRYLRQILQGVSYLHENQVVHRDIKGANILVDSTGQDIRIADFGAAARLATQITGA--GEFQGQLLGTIAFMAPEVLRGESYGRSCDVWSVGCVLIEMATGKPPW 245
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9])

HSP 1 Score: 95.9005 bits (237), Expect = 1.581e-21
Identity = 79/263 (30.04%), Postives = 125/263 (47.53%), Query Frame = 3 
Query: 1473 KLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLK-DNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 2258
            KL EG +  +FKA      + V IK+    +    D Q+I+ E+   Q   S P  V+          L+ ++E    GS++  +K  N  LT ++IK      L+GL++LH  + IHR++   NIL++   + KL  F  +  L   +T +     +G    +  ++APEV+    Y   ADIWS G+  +E+  GKPPY       AI +I       ++   +      K FV  CL  +P+ERAT  EL ++ F+   K
Sbjct:   29 KLGEGSYGSVFKAMHKESGQVVAIKQVPVDT----DLQEIIKEISMMQQCDS-PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDLMKIRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILLNSEGHAKLADFGVAGQL--TDTMAKRNTVIG----TPFWMAPEVIQEVGYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPGQ-WSEDFKDFVSKCLVKNPEERATATELLQHSFIQGAK 279
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Match: EDO47821 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL88])

HSP 1 Score: 93.9745 bits (232), Expect = 2.901e-21
Identity = 71/272 (26.10%), Postives = 119/272 (43.75%), Query Frame = 3 
Query: 1437 LTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDER--FLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            L K    T+F G ++ G+   + + +      D   ++YEK  + +G    +L  L    I       VQ I  C D+    +   +E + GGSI   LK          ++++ QIL G+ +LH N +IHR++   NI++  N  +KL+ F  +K +            +     +  ++APEV+    +G ++DIWS G  + E+  G+PP+  S       I      S    L E   +    FV  C+  D   R + +EL  + FL
Sbjct:   11 LGKGAFGTVFLGLVNTGELIAVKQVELHPNNVDAAERQYEKLQEEVG----LLKSLKHKNI-------VQYIGTCMDDSQCTINIFMEFVPGGSIAQALKRFGAFVEPVFRRYTRQILDGVSYLHNNNVIHRDIKGGNIMLMPNGVIKLIDFGCAKKICMVGAHVSKSNILRSMRGTPYWMAPEVIRETGHGRKSDIWSIGCTVFEMATGQPPW--SNVPPLSAIFAIGNGSPVPRLDESFSAAAIDFVTSCMTRDQDTRPSADELLRHDFL 269
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:101175702])

HSP 1 Score: 113.235 bits (282), Expect = 3.630e-25
Identity = 67/210 (31.90%), Postives = 117/210 (55.71%), Query Frame = 3 
Query: 1641 VQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            VQ +    +  F+   +E + GGS++  L+  W PL N++  I  ++ QIL+GLK+LH N+I HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  G+PP+++  + +A      + +  +  + E +  + K F+  C  PDP  RAT  +L  ++FL +
Sbjct:  714 VQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTRQILEGLKYLHDNQIAHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGRPPFYELGEPQAAMFKVGMFKI-HPEIPESMSLEAKAFILRCFEPDPDRRATAFDLLTDEFLTV 916
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:101175702])

HSP 1 Score: 112.849 bits (281), Expect = 4.617e-25
Identity = 67/210 (31.90%), Postives = 117/210 (55.71%), Query Frame = 3 
Query: 1641 VQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDD--IKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNI 2252
            VQ +    +  F+   +E + GGS++  L+  W PL N++  I  ++ QIL+GLK+LH N+I HR++   N+L++    V K+  F TSK L G    +  + F G  +    Y+APE++++  + YG  ADIWS G  ++E+  G+PP+++  + +A      + +  +  + E +  + K F+  C  PDP  RAT  +L  ++FL +
Sbjct:  704 VQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTRQILEGLKYLHDNQIAHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT--ETFTGTLQ----YMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGRPPFYELGEPQAAMFKVGMFKI-HPEIPESMSLEAKAFILRCFEPDPDRRATAFDLLTDEFLTV 906
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Match: map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:NCBI gene;Acc:101156777])

HSP 1 Score: 111.694 bits (278), Expect = 1.083e-24
Identity = 67/207 (32.37%), Postives = 109/207 (52.66%), Query Frame = 3 
Query: 1638 FVQLIRICKDERFLYGILENMEGGSITTFLKDNW-PLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNV-KLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNR--KQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
             VQ +    +  F+   +E + GGS++  L+  W PL    I  ++ QIL+GL++LH N+I+HR++   N+LV+    V K+  F TSK L G       + F G  +    Y+APE++++  + YGA ADIWS G  ++E+  GKPP F    E    + K      +  + E +  + K F+  C  PDP +R    +L ++ F+
Sbjct:  675 IVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKEATIIFYTRQILEGLRYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAG--VNPCTETFTGTLQ----YMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGKPP-FHELGEPQAAMFKVGMFKIHPEIPESLSLEAKSFILRCFEPDPNKRPITTDLLKDPFI 874
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Match: ENSORLT00000015480.2 (serine/threonine-protein kinase PAK 2 [Source:NCBI gene;Acc:101169249])

HSP 1 Score: 105.531 bits (262), Expect = 1.909e-23
Identity = 72/228 (31.58%), Postives = 123/228 (53.95%), Query Frame = 3 
Query: 1590 ILNELITYQITKSQPRFVQLIR--ICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFL--SEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 2258
            I+NE++  +  K+ P  V  +   +  DE F+  ++E + GGS+T  + +   +    I     ++LQ L+FLH N++IHR++ + N+L+  + +VKL  F       G+  Q   ++    T   + Y +APEVV RK YG + DIWS G++ +E++ G+PPY    +E  +  +  I  +G   L   EK+    K F+  CL  D ++R + +EL ++ FL I K
Sbjct:  244 IINEILVMKELKN-PNIVNFVDSFLVGDELFV--VMEYLAGGSLTDVVTETC-MDEAQIAAVCREVLQALEFLHANQVIHRDIKSDNVLLGMDGSVKLTDF-------GFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYL---NENPLRALYLIATNGTPELQNPEKLSPVFKSFLSRCLEMDVEKRGSGKELLQHPFLKIAK 457
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Match: ENSORLT00000028689.1 (serine/threonine-protein kinase PAK 2 [Source:NCBI gene;Acc:101169249])

HSP 1 Score: 105.531 bits (262), Expect = 2.553e-23
Identity = 72/228 (31.58%), Postives = 123/228 (53.95%), Query Frame = 3 
Query: 1590 ILNELITYQITKSQPRFVQLIR--ICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRY-LAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFL--SEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 2258
            I+NE++  +  K+ P  V  +   +  DE F+  ++E + GGS+T  + +   +    I     ++LQ L+FLH N++IHR++ + N+L+  + +VKL  F       G+  Q   ++    T   + Y +APEVV RK YG + DIWS G++ +E++ G+PPY    +E  +  +  I  +G   L   EK+    K F+  CL  D ++R + +EL ++ FL I K
Sbjct:  281 IINEILVMKELKN-PNIVNFVDSFLVGDELFV--VMEYLAGGSLTDVVTETC-MDEAQIAAVCREVLQALEFLHANQVIHRDIKSDNVLLGMDGSVKLTDF-------GFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYL---NENPLRALYLIATNGTPELQNPEKLSPVFKSFLSRCLEMDVEKRGSGKELLQHPFLKIAK 494
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Match: SMESG000074914.1 (SMESG000074914.1)

HSP 1 Score: 1432.54 bits (3707), Expect = 0.000e+0
Identity = 715/718 (99.58%), Postives = 717/718 (99.86%), Query Frame = 3 
Query:  105 MILFIFIIATVSYGEVPRSFCQNPKPYKVMIGTCASYSEVCYKKDDKDCENLQNVCAQCPSVTEKLLNFLNKNKEDSHIFLYIIISMTAALFLYVIIEVRFKILTKCCCGFKGTASTRNHSILQSRKYIRGTQSKIDEKLTEITELLDFGIDFRIDSNCNVIDLVENSINLKIKSKLDNIAEMIKTTLDAKIDLKMDNIIVLIEKSLTFSNSKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEEKEPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 2258
            MILFIFIIATV+YGEVPRSFCQNPKPYKVM+GTCASYSEVCYKKDDKDCENLQNVCAQCPSVTEKLLNFLNKNKEDSHIFLYIIISMTAALFLYVIIEVRFKILTKCCCGFKGTASTRNHSILQSRKYIRGTQSKIDEKLTEITELLDFGIDFRIDSNCNVIDLVENSINLKIKSKLDNIAEMIKTTLDAKIDLKMDNIIVLIEKSLTFSNSKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEE EPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDEEAIEIIKEIKESGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK
Sbjct:    1 MILFIFIIATVTYGEVPRSFCQNPKPYKVMVGTCASYSEVCYKKDDKDCENLQNVCAQCPSVTEKLLNFLNKNKEDSHIFLYIIISMTAALFLYVIIEVRFKILTKCCCGFKGTASTRNHSILQSRKYIRGTQSKIDEKLTEITELLDFGIDFRIDSNCNVIDLVENSINLKIKSKLDNIAEMIKTTLDAKIDLKMDNIIVLIEKSLTFSNSKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEENEPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDEEAIEIIKEIKESGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 718
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Match: SMESG000074914.1 (SMESG000074914.1)

HSP 1 Score: 1370.91 bits (3547), Expect = 0.000e+0
Identity = 687/689 (99.71%), Postives = 688/689 (99.85%), Query Frame = 3 
Query:  192 MIGTCASYSEVCYKKDDKDCENLQNVCAQCPSVTEKLLNFLNKNKEDSHIFLYIIISMTAALFLYVIIEVRFKILTKCCCGFKGTASTRNHSILQSRKYIRGTQSKIDEKLTEITELLDFGIDFRIDSNCNVIDLVENSINLKIKSKLDNIAEMIKTTLDAKIDLKMDNIIVLIEKSLTFSNSKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEEKEPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 2258
            M+GTCASYSEVCYKKDDKDCENLQNVCAQCPSVTEKLLNFLNKNKEDSHIFLYIIISMTAALFLYVIIEVRFKILTKCCCGFKGTASTRNHSILQSRKYIRGTQSKIDEKLTEITELLDFGIDFRIDSNCNVIDLVENSINLKIKSKLDNIAEMIKTTLDAKIDLKMDNIIVLIEKSLTFSNSKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEE EPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDEEAIEIIKEIKESGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK
Sbjct:    1 MVGTCASYSEVCYKKDDKDCENLQNVCAQCPSVTEKLLNFLNKNKEDSHIFLYIIISMTAALFLYVIIEVRFKILTKCCCGFKGTASTRNHSILQSRKYIRGTQSKIDEKLTEITELLDFGIDFRIDSNCNVIDLVENSINLKIKSKLDNIAEMIKTTLDAKIDLKMDNIIVLIEKSLTFSNSKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEENEPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDEEAIEIIKEIKESGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLNIMK 689
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Match: SMESG000074921.1 (SMESG000074921.1)

HSP 1 Score: 397.512 bits (1020), Expect = 2.270e-127
Identity = 246/736 (33.42%), Postives = 399/736 (54.21%), Query Frame = 3 
Query:  108 ILFIFIIAT-VSYGEVPRSFCQNPKPYKVMIGTCASYSEVCYKKDDKDCENLQNVCAQCPSVTEKLLNFLNKNK--------ED------------SHIFLYIIISMTAALFLYVIIEVRFKILTKCCCGFKGTASTRNHSILQSRKYIRGTQSKIDEKLTEITELLDFGIDFRIDSNCNVIDLVENSINLKIKSKLDNIAEMIKTTLDAKIDLKMDNIIVLIEKSLTFSN-SKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEEKEPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSK-NLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            I+F FI +  +S  E+P S C   KP+K M  +CA++ +VC K  DK+C+N QNVC QCP+    +  FL+           ED            + + +Y I+ M   + + + +EVRFK+ TK         +  N+ IL+SRKY+                                        N  + SK + + + +   ++  ID +++ I   IEK LT      +KF ++GL KPIEL+VN  +NVIQIKR+IC++WP A+   YK M++    +YLDDN YLL  ++SI  T+ C ++  IN  + +V+ +  N+R+P++ Q+ K   + E+K +I+ I       + K+     +L D  T++  +L+DDDWI+II +E G L IKS+F++K    I YSN D + +LK+  A K+  D  + VLF N   L    + +DY+ID +S++ FC L +     +    +++  F +L   ++    E +LIKKY   S+ NL   +DI+ E+  +QI++   +FV+L+ I  DE  LY  +E +E  S+  F+K N PL  + I  W  QIL+GL++LHYN +IH N+  +NI+VD    +KLL F+ S  ++ YET   D  F+  +   +RY APE+ + +   + ADIWSFG +L+ I+ G  PY   ++ E +  I++     + F +  +  +LK F++ CL  +P++R T ++L EN+F+
Sbjct:    7 IIFTFIYSIKISREELPLSMCGIVKPFKTMNNSCANFVDVCVKTGDKECQNFQNVCQQCPAYNYSIQTFLDVRTINDRMSKIEDKMFQNQNIIINTTLVLVYCIMFMICLILVVLFVEVRFKLCTKIFKCLNCRQTQVNYQILKSRKYLE---------------------------------------NDNLFSKWNEVCQDMSRKME-DIDSRINGITGWIEKLLTMPTIVIIKFQVTGLSKPIELNVNLNENVIQIKRRICSRWPAAQRDSYKKMKVIDKGKYLDDNHYLLTQINSIASTLKCSIDDSINPEDFLVISLRSNRRIPDLFQVKKTSTVKEMKILISSINKFISDPVIKEMYEGKDLNDMNTLESYSLRDDDWIKIITRESGDLTIKSLFDDKIQYSISYSNFDSIENLKRNFAKKIQLDSVNLVLFLNELDLKNQKFVYDYDIDMDSSLSFCFLERWSGINITGNAIEKDYFFQLLPGEYNETREKILIKKYSLLSEINLESQKDIIKEMSVFQISQQSEQFVKLLGIYFDEAALYAKMEYIEAVSMLEFIKKNSPLKENKISLWCRQILEGLRYLHYNNMIHGNIRPTNIVVDNKGKLKLLFFNIS--VNIYET---DGLFINYSVFPARYSAPEIFDDEGCTSAADIWSFGSVLIYIVTGSQPYETLSESEVVIQIQKDHRISFSFPTSPVSDELKAFLQNCLIYNPEKRPTAQQLLENEFI 697
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Match: SMESG000074938.1 (SMESG000074938.1)

HSP 1 Score: 395.586 bits (1015), Expect = 3.688e-126
Identity = 256/746 (34.32%), Postives = 410/746 (54.96%), Query Frame = 3 
Query:  111 LFIFIIATVSYGEVPRSFCQNPKPYKVMIGTCASYSEVCYKKDDKDCENLQNVCAQCPSVTEKLLNF--LNKNKEDS---------------------------HIFLYIIISMTAALFLYVIIEVRFKILTKCCCGFKGTASTRNHSILQSRKYIRGTQSKIDEKLTEITELLDFGIDFRIDSNCNVIDLVENSINLKIKSKLDNIAEMIKTTLDAKIDLKMDNIIVLIEKSLTFSNSKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEEKEPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKY-EKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMG-QTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPY--FKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLN 2249
            + +F+I+ V++ E P S C   +P+K M  TC +++E+C KK+D +C N ++VC QCP V    + F  LN+  ED                            +  L  +I +   LF+ ++  +R   L+      K   S         +  I   Q   +E+  ++ + L   I  ++  N    D+++  I  +   K+D   +  K  LD K++     +    +      N   KF +     PIEL+++  +N++QIKR+I +K P  +   YK+M+L YN + LDDNQY    VS  +V + CE+N  ++ + IIVL V+  +R+P+++Q+ K Q ++E+K+II+KI+    FVIF++ + LI   D+  I E  L D DWI++I K   ++ ++S+F+E+E  V+++ + D VS LK   A  +   P+++ LF+ N+YLD+    FDY I+  S VKF C+  L    + + ++D G +S L KAK  +K +D+++KKY E    +L  N  +L EL  +Q  KS  RF++L  I K+E + Y  +ENM+GGSI T +K N PL    I  WS QIL+GLK+LH  + ++R+L TSNIL+D   +VKL S S SKYLH Y  +    E MG Q     RY+APE++ +  YG +AD+WSFG I+VE++ G  PY     TD     I + I++   K+ +  I   LK F+ +CL  +P+ER++ ++L  + FLN
Sbjct:   11 ILLFLIS-VTHQEQPLSICHIDRPFKTMDNTCMNFNELCVKKEDPECNNFKSVCTQCPPVNYTFIMFQKLNRLIEDQKRVEIKTKEINEAVEKLSLKKEIKSVLNSILAFVIILPVLLFIGLLYLIRKNKLSIKVRSRKVKISENEEQGDMLKPLIISQQVSENEEQGDMLKPL--IISQQVSENEEQGDMLKPLIINQQDLKIDERFKEFKLFLDLKLEENFQKLQAF-QGIFANQNKDTKFQLKAAAHPIELNIHIDENIVQIKRKIVSKCPTLRKGCYKIMKLHYNGKVLDDNQYFFSCVSCRDVIISCEVNQSLDPNEIIVLNVHSKERMPDLLQIKKTQAVSELKEIISKIIQRKNFVIFQESKELI---DSELINESKLVDFDWIKVIIKNHEEIFLRSIFDERENLVVEFESSDMVSTLKSNLANNVNSSPDNYALFYYNEYLDDTKLLFDYGINQHSEVKFVCIRNLHDVEVIE-EIDRGYYSVLLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKP---EQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETD----AIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 741
[Close]
BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Match: SMESG000074921.1 (SMESG000074921.1)

HSP 1 Score: 393.275 bits (1009), Expect = 1.615e-125
Identity = 249/754 (33.02%), Postives = 402/754 (53.32%), Query Frame = 3 
Query:  108 ILFIFIIAT-VSYGEVPRSFCQNPKPYKVMIGTCASYSEVCYKKDDKDCENLQNVCAQCPSVTEKLLNFL----------------NKNK----------ED------------SHIFLYIIISMTAALFLYVIIEVRFKILTKCCCGFKGTASTRNHSILQSRKYIRGTQSKIDEKLTEITELLDFGIDFRIDSNCNVIDLVENSINLKIKSKLDNIAEMIKTTLDAKIDLKMDNIIVLIEKSLTFSN-SKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEEKEPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSK-NLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPYFKSTDXXXXXXXXXXXXSGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFL 2246
            I+F FI +  +S  E+P S C   KP+K M  +CA++ +VC K  DK+C+N QNVC QCP+    +  FL                NKN+          ED            + + +Y I+ M   + + + +EVRFK+ TK         +  N+ IL+SRKY+                                        N  + SK + + + +   ++  ID +++ I   IEK LT      +KF ++GL KPIEL+VN  +NVIQIKR+IC++WP A+   YK M++    +YLDDN YLL  ++SI  T+ C ++  IN  + +V+ +  N+R+P++ Q+ K   + E+K +I+ I       + K+     +L D  T++  +L+DDDWI+II +E G L IKS+F++K    I YSN D + +LK+  A K+  D  + VLF N   L    + +DY+ID +S++ FC L +     +    +++  F +L   ++    E +LIKKY   S+ NL   +DI+ E+  +QI++   +FV+L+ I  DE  LY  +E +E  S+  F+K N PL  + I  W  QIL+GL++LHYN +IH N+  +NI+VD    +KLL F+ S  ++ YET   D  F+  +   +RY APE+ + +   + ADIWSFG +L+ I+ G  PY   ++ E +  I++     + F +  +  +LK F++ CL  +P++R T ++L EN+F+
Sbjct:    7 IIFTFIYSIKISREELPLSMCGIVKPFKTMNNSCANFVDVCVKTGDKECQNFQNVCQQCPAYNYSIQTFLDVRTINDRMSKIEEKINKNQNIITYRMSKIEDKMFQNQNIIINTTLVLVYCIMFMICLILVVLFVEVRFKLCTKIFKCLNCRQTQVNYQILKSRKYLE---------------------------------------NDNLFSKWNEVCQDMSRKME-DIDSRINGITGWIEKLLTMPTIVIIKFQVTGLSKPIELNVNLNENVIQIKRRICSRWPAAQRDSYKKMKVIDKGKYLDDNHYLLTQINSIASTLKCSIDDSINPEDFLVISLRSNRRIPDLFQVKKTSTVKEMKILISSINKFISDPVIKEMYEGKDLNDMNTLESYSLRDDDWIKIITRESGDLTIKSLFDDKIQYSISYSNFDSIENLKRNFAKKIQLDSVNLVLFLNELDLKNQKFVYDYDIDMDSSLSFCFLERWSGINITGNAIEKDYFFQLLPGEYNETREKILIKKYSLLSEINLESQKDIIKEMSVFQISQQSEQFVKLLGIYFDEAALYAKMEYIEAVSMLEFIKKNSPLKENKISLWCRQILEGLRYLHYNNMIHGNIRPTNIVVDNKGKLKLLFFNIS--VNIYET---DGLFINYSVFPARYSAPEIFDDEGCTSAADIWSFGSVLIYIVTGSQPYETLSESEVVIQIQKDHRISFSFPTSPVSDELKAFLQNCLIYNPEKRPTAQQLLENEFI 715
The following BLAST results are available for this feature:
BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MAP3K153.832e-2633.33mitogen-activated protein kinase kinase kinase 15 ... [more]
MAP3K51.097e-2431.43mitogen-activated protein kinase kinase kinase 5 [... [more]
PAK18.683e-2330.37p21 (RAC1) activated kinase 1 [Source:HGNC Symbol;... [more]
PAK23.016e-2229.74p21 (RAC1) activated kinase 2 [Source:HGNC Symbol;... [more]
STK255.896e-2232.62serine/threonine kinase 25 [Source:HGNC Symbol;Acc... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nsy-11.312e-2231.58Mitogen-activated protein kinase kinase kinase nsy... [more]
nsy-11.388e-2231.58Mitogen-activated protein kinase kinase kinase nsy... [more]
max-21.486e-2030.00Serine/threonine-protein kinase max-2 [Source:Uni... [more]
aak-11.956e-1924.145'-AMP-activated protein kinase catalytic subunit ... [more]
aak-11.956e-1924.145'-AMP-activated protein kinase catalytic subunit ... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ask13.164e-2230.08gene:FBgn0014006 transcript:FBtr0083819[more]
Ask13.782e-2230.08gene:FBgn0014006 transcript:FBtr0300256[more]
Pak34.531e-2132.29gene:FBgn0044826 transcript:FBtr0330047[more]
Pak34.635e-2132.29gene:FBgn0044826 transcript:FBtr0083312[more]
Pak34.635e-2132.29gene:FBgn0044826 transcript:FBtr0305003[more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
map3k58.981e-2632.23mitogen-activated protein kinase kinase kinase 5 [... [more]
map3k59.489e-2632.23mitogen-activated protein kinase kinase kinase 5 [... [more]
map3k59.508e-2632.23mitogen-activated protein kinase kinase kinase 5 [... [more]
map3k51.005e-2532.23mitogen-activated protein kinase kinase kinase 5 [... [more]
map3k51.021e-2532.23mitogen-activated protein kinase kinase kinase 5 [... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MAP3K151.308e-2828.27mitogen-activated protein kinase kinase kinase 5 [... [more]
MAP3K151.424e-2828.27mitogen-activated protein kinase kinase kinase 5 [... [more]
MAP3K151.427e-2828.27mitogen-activated protein kinase kinase kinase 5 [... [more]
MAP3K151.543e-2828.27mitogen-activated protein kinase kinase kinase 5 [... [more]
MAP3K151.616e-2828.27mitogen-activated protein kinase kinase kinase 5 [... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Map3k152.768e-2627.05mitogen-activated protein kinase kinase kinase 15 ... [more]
Map3k56.338e-2529.18mitogen-activated protein kinase kinase kinase 5 [... [more]
Map3k56.468e-2529.18mitogen-activated protein kinase kinase kinase 5 [... [more]
Pak14.703e-2330.37p21 (RAC1) activated kinase 1 [Source:MGI Symbol;A... [more]
Pak14.703e-2330.37p21 (RAC1) activated kinase 1 [Source:MGI Symbol;A... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6ZN16|M3K15_HUMAN1.840e-2533.33Mitogen-activated protein kinase kinase kinase 15 ... [more]
sp|A2AQW0|M3K15_MOUSE1.936e-2527.05Mitogen-activated protein kinase kinase kinase 15 ... [more]
sp|O35099|M3K5_MOUSE4.524e-2429.18Mitogen-activated protein kinase kinase kinase 5 O... [more]
sp|Q54R82|MKKA_DICDI4.987e-2432.02Mitogen-activated protein kinase kinase kinase A O... [more]
sp|Q99683|M3K5_HUMAN5.269e-2431.43Mitogen-activated protein kinase kinase kinase 5 O... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0BC868.251e-2934.63Protein kinase domain-containing protein OS=Parame... [more]
A0EFT41.221e-2634.52Protein kinase domain-containing protein OS=Parame... [more]
A0A060SKW91.566e-2632.70Protein kinase domain-containing protein OS=Pycnop... [more]
A0A1D2N3M81.614e-2630.57Mitogen-activated protein kinase kinase kinase 15 ... [more]
A0A1B6HXA01.973e-2630.65Protein kinase domain-containing protein (Fragment... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
map3k152.513e-2632.43mitogen-activated protein kinase kinase kinase 15 ... [more]
map3k51.226e-2532.86mitogen-activated protein kinase kinase kinase 5 [... [more]
map3k51.326e-2532.86mitogen-activated protein kinase kinase kinase 5 [... [more]
map3k51.387e-2532.86mitogen-activated protein kinase kinase kinase 5 [... [more]
pak13.747e-2330.22p21 protein (Cdc42/Rac)-activated kinase 1 [Source... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
map3k21.184e-2238.51mitogen-activated protein kinase kinase kinase 2 [... [more]
plk38.122e-2230.88polo-like kinase 3 (Drosophila) [Source:ZFIN;Acc:Z... [more]
pak43.038e-1928.80p21 protein (Cdc42/Rac)-activated kinase 4 [Source... [more]
ENSPMAT00000006670.13.085e-1926.74pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene... [more]
stk25a1.170e-1831.09serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-G... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
STE208.178e-2530.74Cdc42p-activated signal transducing kinase; involv... [more]
SKM13.282e-2330.47Member of the PAK family of serine/threonine prote... [more]
CLA47.383e-2332.50Cdc42p-activated signal transducing kinase; member... [more]
PKH21.009e-2034.78Serine/threonine protein kinase; involved in sphin... [more]
CDC53.993e-1928.01Polo-like kinase; controls targeting and activatio... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO414104.068e-2537.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO361501.051e-2327.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO279762.633e-2331.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO428451.581e-2130.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO478212.901e-2126.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
map3k53.630e-2531.90mitogen-activated protein kinase kinase kinase 5 [... [more]
map3k54.617e-2531.90mitogen-activated protein kinase kinase kinase 5 [... [more]
map3k151.083e-2432.37mitogen-activated protein kinase kinase kinase 15 ... [more]
ENSORLT00000015480.21.909e-2331.58serine/threonine-protein kinase PAK 2 [Source:NCBI... [more]
ENSORLT00000028689.12.553e-2331.58serine/threonine-protein kinase PAK 2 [Source:NCBI... [more]
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BLAST of Non-specific serine/threonine protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000074914.10.000e+099.58SMESG000074914.1[more]
SMESG000074914.10.000e+099.71SMESG000074914.1[more]
SMESG000074921.12.270e-12733.42SMESG000074921.1[more]
SMESG000074938.13.688e-12634.32SMESG000074938.1[more]
SMESG000074921.11.615e-12533.02SMESG000074921.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024109 ID=SMED30024109|Name=Non-specific serine/threonine protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=2419bp
TTTTCAATTTTATTTTTGTCTCGGGATATAAATAAAACAATCTTATTATC
CAATCAAATGACAGATTATTATTTGGTTCTTATTTGAATTTTACTATCGA
TCATATGATTTTATTTATTTTTATAATTGCGACAGTTTCCTATGGGGAGG
TGCCCCGGTCTTTTTGCCAAAATCCAAAACCTTATAAGGTAATGATAGGA
ACATGTGCAAGTTACTCCGAAGTATGCTATAAAAAAGATGATAAAGATTG
CGAGAATCTGCAAAACGTTTGCGCACAGTGCCCAAGTGTCACGGAAAAAC
TATTAAATTTTCTAAATAAAAATAAAGAAGATTCACACATATTCTTGTAT
ATAATTATAAGTATGACTGCTGCATTGTTCTTATATGTAATAATAGAAGT
AAGATTCAAAATTTTGACCAAATGCTGCTGTGGTTTCAAAGGGACAGCTT
CTACAAGAAATCACAGTATTCTTCAAAGCCGAAAATATATAAGAGGGACT
CAGTCAAAGATTGACGAAAAACTTACGGAGATAACGGAGCTCTTGGATTT
CGGAATTGATTTTAGAATCGACTCAAATTGCAATGTGATTGATTTGGTAG
AGAATTCTATCAATTTGAAAATTAAATCAAAATTGGATAATATTGCTGAA
ATGATAAAGACTACGCTGGATGCAAAAATTGATTTGAAAATGGACAATAT
TATTGTTTTAATAGAGAAATCATTGACGTTTTCTAATTCGAAATTGAAAT
TTCTGATTTCCGGATTGGAAAAACCAATTGAGTTGCATGTGAATGAAAAG
GATAACGTCATTCAGATCAAAAGACAAATTTGTGCCAAATGGCCGAAAGC
TAAGCCTCATTATTACAAGTTAATGAGGCTTAGATATAATGAAAGGTATC
TCGATGACAACCAATACCTCTTACTCAGTGTTTCTTCCATAAATGTCACT
GTTGTCTGTGAGATGAATCACAAAATCAATCACAGCAACATAATTGTATT
GAAAGTAAACGGAAATAAACGACTACCGGAAATGATACAACTCCATAAAG
ATCAGAAAATTAACGAGATTAAACAAATAATTGCGAAAATTGTCTATTCG
GCCGAATTTGTCATATTTAAAGATGGACAGAATTTAATTGAATTAAAAGA
CAACTTAACAATTAAAGAATGTAATCTGAAAGATGATGATTGGATACGAA
TAATTGCAAAAGAAAAAGGGAAATTAGTTATTAAATCTGTTTTCGAAGAA
AAAGAACCCTGTGTGATAGATTACTCGAATCTTGATCATGTGAGTGATTT
GAAGAAAAAGGCTGCTATGAAAATGATCTGCGACCCGGAAGATTTTGTTT
TATTCCATAACAATAAATATTTGGACGAAGATAATTACTTTTTCGATTAT
GAAATAGACAATGAATCTACAGTGAAGTTTTGTTGTTTGACAAAATTAGG
TCAGTCGACTTTATTTGACGGAAAACTCGACGAAGGAGATTTCTCGGAAT
TGTTCAAAGCTAAATGGGGTGCCAAATTTGAAGATGTATTAATAAAAAAG
TACGAGAAATCCAGCAAAAATTTAGGCGATAATCAGGATATTTTGAATGA
GCTCATCACATACCAAATCACAAAGTCTCAACCGAGATTTGTTCAACTCA
TCAGAATATGTAAAGATGAGAGGTTTTTGTATGGTATTTTAGAAAATATG
GAAGGAGGTTCTATTACAACGTTTCTAAAAGATAATTGGCCTTTAACAAA
CGATGATATTAAGAAGTGGTCGTTTCAGATTTTACAGGGCCTGAAGTTTC
TGCATTATAATAAGATAATCCACCGAAATCTAAGTACTTCAAATATTTTG
GTTGACGGAAATAGAAATGTAAAATTACTCAGTTTTTCCACCTCGAAATA
CTTACATGGATATGAAACGCAATCTTTTGACAAGGAGTTCATGGGACAGA
CGGAGAAATCATCGCGATATCTCGCTCCTGAAGTAGTAAACCGAAAGCAA
TACGGTGCACAAGCTGACATTTGGTCATTTGGTATGATATTAGTTGAGAT
CATAAACGGAAAACCTCCATATTTTAAAAGCACTGACGAAGAAGCAATAG
AAATCATTAAAGAAATCAAAGAGTCGGGATATAAATTTTTGTCAGAGAAA
ATTTGTTCACAACTAAAACATTTTGTGGAGATCTGTTTACATCCAGATCC
AAAAGAAAGAGCAACTATTGAAGAGCTGTTTGAGAATAAATTCTTGAATA
TCATGAAATAAATCTACCAAACCTTTATGATCCAATATTCGTAAAAAGTA
AAACAGATGAGGAATGATTGTGTTAATAATATGTGATAAATGTTGGGCAA
TTATTTGTGAGTTTTAGAGGATGTTCAATTATTCATTTTAAAACACATTT
AAGTTGAGAATATGAAAAC
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protein sequence of SMED30024109-orf-1

>SMED30024109-orf-1 ID=SMED30024109-orf-1|Name=SMED30024109-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=719bp
MILFIFIIATVSYGEVPRSFCQNPKPYKVMIGTCASYSEVCYKKDDKDCE
NLQNVCAQCPSVTEKLLNFLNKNKEDSHIFLYIIISMTAALFLYVIIEVR
FKILTKCCCGFKGTASTRNHSILQSRKYIRGTQSKIDEKLTEITELLDFG
IDFRIDSNCNVIDLVENSINLKIKSKLDNIAEMIKTTLDAKIDLKMDNII
VLIEKSLTFSNSKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAK
PHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLK
VNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDN
LTIKECNLKDDDWIRIIAKEKGKLVIKSVFEEKEPCVIDYSNLDHVSDLK
KKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQ
STLFDGKLDEGDFSELFKAKWGAKFEDVLIKKYEKSSKNLGDNQDILNEL
ITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTND
DIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYL
HGYETQSFDKEFMGQTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEII
NGKPPYFKSTDEEAIEIIKEIKESGYKFLSEKICSQLKHFVEICLHPDPK
ERATIEELFENKFLNIMK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR029071Ubiquitin-like_domsf
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0045296cadherin binding
GO:0046872metal ion binding
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0004702signal transducer, downstream of receptor, with serine/threonine kinase activity
GO:0005515protein binding
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0030336negative regulation of cell migration
GO:0042542response to hydrogen peroxide
GO:0046777protein autophosphorylation
GO:0048679regulation of axon regeneration
GO:0097194execution phase of apoptosis
GO:0006915apoptotic process
GO:0007165signal transduction
GO:0008631intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0016310phosphorylation
GO:0023014signal transduction by protein phosphorylation
Vocabulary: cellular component
TermDefinition
GO:0070062extracellular exosome
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005730nucleolus
GO:0005737cytoplasm
GO:0005829cytosol
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 452..714
e-value: 3.8E-40
score: 149.4
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 457..714
e-value: 7.5E-48
score: 163.2
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 452..714
score: 37.177
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 453..718
e-value: 8.0E-56
score: 191.2
NoneNo IPR availableGENE3DG3DSA:3.10.20.90coord: 373..443
e-value: 5.1E-6
score: 28.1
NoneNo IPR availablePANTHERPTHR24347:SF412CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE Icoord: 441..714
NoneNo IPR availablePANTHERPTHR24347SERINE/THREONINE-PROTEIN KINASEcoord: 441..714
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..14
score: 0.704
NoneNo IPR availableTMHMMTMhelixcoord: 78..97
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 455..715
IPR029071Ubiquitin-like domain superfamilySUPERFAMILYSSF54236Ubiquitin-likecoord: 288..367
IPR029071Ubiquitin-like domain superfamilySUPERFAMILYSSF54236Ubiquitin-likecoord: 374..441
IPR029071Ubiquitin-like domain superfamilySUPERFAMILYSSF54236Ubiquitin-likecoord: 222..272