Protein SDA1

Overview


Name	Protein SDA1
Smed ID	SMED30024098
Length (bp)	2131

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein SDA1 (SMED30024098) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein SDA1 (SMED30024098) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein SDA1 (SMED30024098) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein SDA1 (SMED30024098) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30024098

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30024098	h1SMcG0004051	SmedASXL_014288	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30024098	h1SMcG0004051	SmedASXL_014288	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
Smed sexual biotype	SMED30024098	h1SMcG0004051	Contig48869	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30024098	h1SMcG0004051	Contig48869	newmark_ests	PMID:29674431 Fincher et al., 2018
epidermis	SMED30024098	h1SMcG0004051	dd_Smed_v4_2857_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30024098	h1SMcG0004051	dd_Smed_v4_2857_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30024098	h1SMcG0004051	dd_Smed_v4_2857_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30024098	h1SMcG0004051	dd_Smed_v4_2857_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30024098	h1SMcG0004051	dd_Smed_v4_2857_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
testis	SMED30024098	h1SMcG0004051	KU852686	smed_ncbi_20240424	PMID:27330085 Iyer et al., 2016
male germ cell	SMED30024098	h1SMcG0004051	KU852686	smed_ncbi_20240424	PMID:27330085 Iyer et al., 2016

Note: Hover over icons to view figure legend

Homology

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BLAST of Protein SDA1 vs. Ensembl Human
Match: SDAD1 (SDA1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25537])

HSP 1 Score: 270.011 bits (689), Expect = 7.182e-80
Identity = 215/594 (36.20%), Postives = 340/594 (57.24%), Query Frame = 2

Query:  260 RIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAAR----IFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYE-DWVDIQQ-SDEEEMPDPKELRD-P-EERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            R+   K L+ L NKN++      E    L  C DK LR+ +   I+ ++K  N K      N K  ++LQ F+   + +    AA+    + + L+ +NIW D  ++NVI   C     K+ V AL FFL K    K DSDSESE +       R L + +  GKKS   +K L+K +  +K++ K KK +          N  AI  + DPQ FAE LL +++  K    ++MM++ L+SRL+G H+L L NFY ++  FL  H  +VT +L++AAQASH  V P+ IQ ++  +A+ F  D  S + + +G+N+I+EI  RCP AM +ELL  L ++  H+DKNV+ +AR+L+ L+R +NP ML K  +G+PTEA+++  VQ         +G L++  +IPGAE++E E+ E    +++ +ES S +S+EE+ + +W+D+Q  SDEE+    K+L   P EER+  A  +S S + T E+   I+   ++K+   A  K++KR      IEIDSD     +P    E ++ R I ++ KK K+ +E ++ +   G+ DR++F     + NP SS+TN+EK K+KN+MM+ +
Sbjct:   97 RMTFCKALILLRNKNLINPSSLLELFFELFRCHDKLLRKTLYTHIVTDIKNINAKHK----NNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEDEKQDSDSESEDDGPT---ARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVF--------NFSAIHLIHDPQDFAEKLLKQLECCKERFEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQ--------EYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTS-LSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKY----IEIDSDE----EPR--GELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRY 656

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BLAST of Protein SDA1 vs. Ensembl Human
Match: SDAD1 (SDA1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25537])

HSP 1 Score: 253.832 bits (647), Expect = 4.281e-74
Identity = 206/570 (36.14%), Postives = 329/570 (57.72%), Query Frame = 2

Query:  344 LVTCE----DKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAAR----IFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYE-DWVDIQQ-SDEEEMPDPKELRD-P-EERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            L++C     D +LR  +   I+ ++K  N K      N K  ++LQ F+   + +    AA+    + + L+ +NIW D  ++NVI   C     K+ V AL FFL K    K DSDSESE +       R L + +  GKKS   +K L+K +  +K++ K KK +          N  AI  + DPQ FAE LL +++  K    ++MM++ L+SRL+G H+L L NFY ++  FL  H  +VT +L++AAQASH  V P+ IQ ++  +A+ F  D  S + + +G+N+I+EI  RCP AM +ELL  L ++  H+DKNV+ +AR+L+ L+R +NP ML K  +G+PTEA+++  VQ         +G L++  +IPGAE++E E+ E    +++ +ES S +S+EE+ + +W+D+Q  SDEE+    K+L   P EER+  A  +S S + T E+   I+   ++K+   A  K++KR      IEIDSD     +P    E ++ R I ++ KK K+ +E ++ +   G+ DR++F     + NP SS+TN+EK K+KN+MM+ +
Sbjct:   84 LLSCNHTVLDPDLRMTLYTHIVTDIKNINAKHK----NNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEDEKQDSDSESEDDGPT---ARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEV--------FNFSAIHLIHDPQDFAEKLLKQLECCKERFEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQ--------EYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTS-LSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKY----IEIDSDE----EPR--GELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRY 619

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BLAST of Protein SDA1 vs. Ensembl Celegans
Match: pro-3 (pep chromosome:WBcel235:V:19101961:19118412:-1 gene:WBGene00012676.1 transcript:Y39B6A.14.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:pro-3)

HSP 1 Score: 207.994 bits (528), Expect = 5.720e-57
Identity = 142/419 (33.89%), Postives = 233/419 (55.61%), Query Frame = 2

Query:  131 VVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLK---LAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMKKAPI---HIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTE 1369
            V+FLS L K+    +    K+FS  + E++++           R+   K L+ L N++++  +   E    LV  EDK LR+ +++ I   LK+  +K   V++  K + L    +K+     A  A  + +  F +  W D  + NVIA  C H  AK++VT++KFFL    +  D  DS+     ++ D  + LK    + R  KK++ R+K++++      +K  SKKKK   +  S ECN++AIQ L DPQ F + L   ++   +    +R+  + L +R+IG H+L  ++FYSY+  FL     DVT +L+YAAQA HE V PD ++ ++++IA+ F  D  S + + +G+N+IREI   CP A  +ELL  L E+  +++KNV  AARSL+ L+R +NP +L +  +G+P E
Sbjct:   97 VLFLSGLAKHYPKES----KQFSDSLFELLREQG--AGLDPEVRMAFCKALVLLRNQDMIDPIILMETFFELVKVEDKVLRKFLLSSISAHLKRVYHKKKDVKMLGKIQNLCFSKMKDSRSIVARAAQLVCIDAFRRKFWRDARTANVIAQACFHKVAKIQVTSMKFFLGSENENGDAEDSDEMDSDAE-DNTKTLKEVMTSFRNVKKTRKREKNVER-----AKKMISKKKKAKKEGRSKECNLMAIQSLYDPQEFVDRLFGAVEAKKMDNFEVRLFKIALCARIIGIHRLHTLSFYSYLHRFLQPKQRDVTKILLYAAQACHEMVPPDTVEQLIRVIANNFVTDRNSPEAMTVGINAIREILSNCPFAATEELLRDLSEYKTYKNKNVSMAARSLITLFRAVNPKLLARKDRGKPQE 503

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BLAST of Protein SDA1 vs. Ensembl Fly
Match: Mys45A (gene:FBgn0033379 transcript:FBtr0088628)

HSP 1 Score: 217.624 bits (553), Expect = 7.788e-61
Identity = 146/431 (33.87%), Postives = 224/431 (51.97%), Query Frame = 2

Query:  125 EFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADC-CLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMKKAP--IHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAAR 1408
            + V+F++ + +      E   KR S ++       ++  V   + R    K L+ L NKN+VP+L+  E    L+ C DK LR  +   I+ ++K  N K   ++LN   +  +   +K+     A  +A I + L+ KNIW D  ++NVIA   C     KV VT+LKFFL    + +++              ++   +A+RV KK+K R K L +         K   K       +   N   I  + +PQ  AE L  +++       +++M L+++SRLIG H L L  FY YI  FL  H   VT +L +AAQASHE V  D I+P++K IA+ F  +  S   +A+GLN+ REIC+RCP AM ++LL  L  +  +++K+V+ AARSL+ LYRE  PA+L K  +GR TEA  +  V+    R
Sbjct:   58 DIVMFVAQVAQCYPAVCEEFPKRLSDLL------KNYATVLDPAMRNCFVKALILLRNKNLVPALDILELFFQLLRCPDKNLRTFLQTHIVTDIKNMNAKHKDMKLNSSLQAFMYSMLKDANPKAAKMSADIMIELYKKNIWNDSKTVNVIATVGCFSKVTKVLVTSLKFFLGHDEEDEEEDTDSENEV-----DLKGALMANRVNKKTKKRTKQLAQ-------IKKQAVKAQKKKKNAPAFNFSGIHLVHNPQGMAEGLFKQLQATNERFEVKLMHLDVISRLIGIHDLFLFGFYPYITRFLQPHQRQVTRVLQFAAQASHELVPGDIIEPILKTIANNFITERNSSDVMAIGLNATREICMRCPLAMGEDLLQDLAMYKTYKEKSVMMAARSLITLYREQLPALLHKKDRGRQTEAQAERKVRAYGER 470

HSP 2 Score: 56.6102 bits (135), Expect = 6.713e-8
Identity = 28/64 (43.75%), Postives = 41/64 (64.06%), Query Frame = 2

Query: 1811 SEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMV 2002
            +EFV    I  + KK K  +E ++E+++ GR DRE+FG+   R N + S TNREK K KN+ M+
Sbjct:  619 AEFVKLNSIEMIYKKRKHDKESRLETVQAGRQDRERFGWKDGRVNEHCSKTNREKRKTKNFGML 682

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BLAST of Protein SDA1 vs. Ensembl Zebrafish
Match: sdad1 (SDA1 domain containing 1 [Source:NCBI gene;Acc:286746])

HSP 1 Score: 259.996 bits (663), Expect = 2.397e-76
Identity = 203/636 (31.92%), Postives = 330/636 (51.89%), Query Frame = 2

Query:  125 EFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMKKAP--IHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEEEMPDPKELRD--PEERRKLAEEM-SYSHIFT-DXXXXXXXXXXXXXXXXGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMV 2002
            E V+FL+     V H     +  F   + +++  +++  V  S  R+   K L+ L NK++V           L+ C DK LR+ +   I+ ++K  N K      N K    LQ F+   + +    AA+I     V L+ +NIW D  ++NVI   C     K+ V  LKFFL K    K D DSESE E S     R L + +  GKK+   +K L+K             KK          N  AI  + DPQ F+E LL +++ +     +++MM+EL+SRL+G H+L L NFY ++  FL  H  +VT +L+ AAQ+SH+ V P+ I+PV+  IA+ F  D  S + + +G+N+I+E+  RCP +M ++LL  L ++  H+DKNV+ +AR L++L+R++NP ML +  +GRPTE++ +  +          +G L +  +IP       E  +   +EDE+    + +SD++E  +WV++  S +E+  +  E     PEE RK    M S S + T D+        + K+      K +KR   D++ E   + GE++         + R I ++ KK K+ +E ++ +   GR DR++F     + NP +ST+N+EK +KKN+MM+
Sbjct:   58 ELVMFLA----QVGHCYLEELSDFPQQLTDLL--LNYHTVLESDLRMTFCKALIMLRNKDLVSPTSLLGLFFELLRCHDKLLRKTLYTHIVTDIKNINAKHK----NNKMNTTLQNFMYTMLRDSNPIAAKISLDVMVELYRRNIWNDAKTVNVITTACFSKVTKILVAGLKFFLGKDEDEKKDDDSESEDEGST---ARDLMMRYSTGKKTSKNKKKLEK--------AMKVLKKHKKKKKVEVFNFSAIHLIHDPQDFSEKLLKQLESSNERFEVKIMMMELISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLCAAQSSHQLVPPEIIEPVIMTIANNFVTDRNSGEVMTVGINAIKEVVARCPLSMSEDLLQDLTQYKSHKDKNVVMSARGLIQLFRDLNPKMLTRKDRGRPTESSKEAKIH--------KYGELEAKDYIP--GAEVLEAEKAEDEEDEDGWESASMSDDDEDGEWVNVHHSSDEDQAEVAEKLQSIPEEERKAKAAMVSTSRLLTQDDFKKIRVAQMAKEVGNAPGKGQKRKNVDSDEE---ERGELL---------SLRDIERLHKKPKSDKETRLATAMAGRTDRKEFTKKRGKLNPYASTSNKEKKRKKNFMMM 650

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BLAST of Protein SDA1 vs. Ensembl Zebrafish
Match: sdad1 (SDA1 domain containing 1 [Source:NCBI gene;Acc:286746])

HSP 1 Score: 66.2402 bits (160), Expect = 8.198e-12
Identity = 44/142 (30.99%), Postives = 66/142 (46.48%), Query Frame = 2

Query:  227 VSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLN 640
            +++  V  S  R+   K L+ L NK++V           L+ C DK LR+ +   I+ ++K  N K      N K    LQ F+   + +    AA+I     V L+ +NIW D  ++NVI   C     K+ V  LKFFL 
Sbjct:   61 LNYHTVLESDLRMTFCKALIMLRNKDLVSPTSLLGLFFELLRCHDKLLRKTLYTHIVTDIKNINAKHK----NNKMNTTLQNFMYTMLRDSNPIAAKISLDVMVELYRRNIWNDAKTVNVITTACFSKVTKILVAGLKFFLG 198

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BLAST of Protein SDA1 vs. Ensembl Xenopus
Match: sdad1 (SDA1 domain containing 1 [Source:NCBI gene;Acc:100124509])

HSP 1 Score: 257.299 bits (656), Expect = 3.647e-75
Identity = 205/607 (33.77%), Postives = 336/607 (55.35%), Query Frame = 2

Query:  230 SFIKVYHS----SYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEE---EMPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            S ++V+H+      R+ + K L+ L NKN++      E    L+ C+DK LR+ +   I+ ++K  N K      N K    LQ F+   + ++   AA+I     + L+ +NIW D  ++NVI+  C     K+ V ALKFFL K  + KD      +   +     R L + +  GKK+   +K L+K +  +K+  K K+ +          N  AI  + DPQ FAE LL +++  K    +++M ++L+SRL+G H+L L NFY ++  FL  H  +VT +L+YAAQA+H  V P+  Q V++ IA+ F  D  S + + +G+N+I+E+  RCP AM +ELL  L  +  H+DKNV  +ARSL++L+R +NP ML K  +G+PTEA+ +  +         A+G L++  +IPGAE++E EQ +    E+++    + +SD++E  +W+D+  S +E   E+ D  +    EER+  A  +S S + + E+   I+   L K+   A  K+ KR      IEIDSD  E        E ++ R I  + KK K+ +E ++ ++  GR DR++F    ++ NP++S+TN+EK K KN+MM+ +
Sbjct:   83 SLLRVHHTVMDPDQRMTLCKALILLRNKNLISPSVLLELFFELLRCQDKLLRKTLYTHIVTDIKNINAKHK----NNKVNTTLQNFMYTMVRDNNAIAAKISLDVMIELYRRNIWNDAKTVNVISTSCFSKVTKILVAALKFFLGKDEEKKDSDSESEDEGPT----ARDLMVRYSTGKKNTKNKKKLEKAMKVLKKHKKKKRPEV--------FNFSAIHLVHDPQEFAEKLLKQLEASKERFEVKLMHMDLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLYAAQATHHLVPPEISQSVLRTIANNFVTDRNSGEVMTVGINAIKELTARCPLAMTEELLQDLALYKTHKDKNVSMSARSLIQLFRSLNPEMLQKKFRGKPTEASKEARIH--------AYGELDAKDYIPGAEVLEVEQEKTEEPEEDDGWESASLSDDDENGEWIDVHHSSDEEQQEVADKIQAMPAEERKAKAATVSASRLLSQEDFKKIRLAQLAKEMNNAPGKSVKRKN----IEIDSDEEE-----RSGELLSLRDIEHLHKKPKSDKETRLATVMAGRTDRKEFVRKKSKMNPHASSTNKEKKKNKNFMMMRY 656

[Close]

BLAST of Protein SDA1 vs. Ensembl Xenopus
Match: sdad1 (SDA1 domain containing 1 [Source:NCBI gene;Acc:100124509])

HSP 1 Score: 244.202 bits (622), Expect = 4.047e-70
Identity = 204/635 (32.13%), Postives = 335/635 (52.76%), Query Frame = 2

Query:  230 SFIKVYHS----SYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALK----------------------------FFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEE---EMPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            S ++V+H+      R+ + K L+ L NKN++      E    L+ C+DK LR+ +   I+ ++K  N K      N K    LQ F+   + ++   AA+I     + L+ +NIW D  ++NVI+  C     K+ V ALK                            FF  K A+ K  +         +    R L + +  GKK+   +K L+K +  +K+  K K+ +          N  AI  + DPQ FAE LL +++  K    +++M ++L+SRL+G H+L L NFY ++  FL  H  +VT +L+YAAQA+H  V P+  Q V++ IA+ F  D  S + + +G+N+I+E+  RCP AM +ELL  L  +  H+DKNV  +ARSL++L+R +NP ML K  +G+PTEA+ +  +         A+G L++  +IPGAE++E EQ +    E+++    + +SD++E  +W+D+  S +E   E+ D  +    EER+  A  +S S + + E+   I+   L K+   A  K+ KR      IEIDSD  E        E ++ R I  + KK K+ +E ++ ++  GR DR++F    ++ NP++S+TN+EK K KN+MM+ +
Sbjct:   83 SLLRVHHTVMDPDQRMTLCKALILLRNKNLISPSVLLELFFELLRCQDKLLRKTLYTHIVTDIKNINAKHK----NNKVNTTLQNFMYTMVRDNNAIAAKISLDVMIELYRRNIWNDAKTVNVISTSCFSKVTKILVAALKFFLGKDEEKKDSDSESEVRLFSGVVLVIFFQCKIAETKKKNKLLIYFLKDEGPTARDLMVRYSTGKKNTKNKKKLEKAMKVLKKHKKKKRPEV--------FNFSAIHLVHDPQEFAEKLLKQLEASKERFEVKLMHMDLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLYAAQATHHLVPPEISQSVLRTIANNFVTDRNSGEVMTVGINAIKELTARCPLAMTEELLQDLALYKTHKDKNVSMSARSLIQLFRSLNPEMLQKKFRGKPTEASKEARIH--------AYGELDAKDYIPGAEVLEVEQEKTEEPEEDDGWESASLSDDDENGEWIDVHHSSDEEQQEVADKIQAMPAEERKAKAATVSASRLLSQEDFKKIRLAQLAKEMNNAPGKSVKRKN----IEIDSDEEE-----RSGELLSLRDIEHLHKKPKSDKETRLATVMAGRTDRKEFVRKKSKMNPHASSTNKEKKKNKNFMMMRY 688

[Close]

BLAST of Protein SDA1 vs. Ensembl Xenopus
Match: sdad1 (SDA1 domain containing 1 [Source:NCBI gene;Acc:100124509])

HSP 1 Score: 234.572 bits (597), Expect = 6.634e-67
Identity = 200/610 (32.79%), Postives = 331/610 (54.26%), Query Frame = 2

Query:  230 SFIKVYHS----SYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHK--LQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEEE----MPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            S ++V+H+      R+ + K L+ L NKN++      E    L+ C+DK LR+ +   I+ ++K  N K      N K    LQ F+   + ++   AA+I     + L+ +NIW D  ++NVI+  C     K+ V ALKFFL K  + KD      +   +     R L + +  GKK+   +K L+K +  +K+  K K+ +          N  AI  + DPQ FAE LL +++  K    +++M ++L+SRL+G H+    L+ FY           A+VT +L+YAAQA+H  V P+  Q V++ IA+ F  D  S + + +G+N+I+E+  RCP AM +ELL  L  +  H+DKNV  +ARSL++L+R +NP ML K  +G+PTEA+ +  +         A+G L++  +IPGAE++E EQ +    E+++    + +SD++E  +W+D+  S +EE    + +  +    EER+  A  +S S + + E+   I+   L K+   A  K+ KR      IEIDSD  E        E ++ R I  + KK K+ +E ++ ++  GR DR++F    ++ NP++S+TN+EK K KN+MM+ +
Sbjct:   83 SLLRVHHTVMDPDQRMTLCKALILLRNKNLISPSVLLELFFELLRCQDKLLRKTLYTHIVTDIKNINAKHK----NNKVNTTLQNFMYTMVRDNNAIAAKISLDVMIELYRRNIWNDAKTVNVISTSCFSKVTKILVAALKFFLGKDEEKKDSDSESEDEGPT----ARDLMVRYSTGKKNTKNKKKLEKAMKVLKKHKKKKRPEV--------FNFSAIHLVHDPQEFAEKLLKQLEASKERFEVKLMHMDLISRLVGIHEQTFTLIIFYH----------AEVTKILLYAAQATHHLVPPEISQSVLRTIANNFVTDRNSGEVMTVGINAIKELTARCPLAMTEELLQDLALYKTHKDKNVSMSARSLIQLFRSLNPEMLQKKFRGKPTEASKEARIH--------AYGELDAKDYIPGAEVLEVEQEKTEEPEEDDGWESASLSDDDENGEWIDVHHSSDEEQQEVVSNKIQAMPAEERKAKAATVSASRLLSQEDFKKIRLAQLAKEMNNAPGKSVKRKN----IEIDSDEEE-----RSGELLSLRDIEHLHKKPKSDKETRLATVMAGRTDRKEFVRKKSKMNPHASSTNKEKKKNKNFMMMRY 649

[Close]

BLAST of Protein SDA1 vs. Ensembl Xenopus
Match: sdad1 (SDA1 domain containing 1 [Source:NCBI gene;Acc:100124509])

HSP 1 Score: 218.394 bits (555), Expect = 3.971e-61
Identity = 193/607 (31.80%), Postives = 318/607 (52.39%), Query Frame = 2

Query:  230 SFIKVYHS----SYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEE---EMPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            S ++V+H+      R+ + K L+ L NKN++      E    L+ C+DK LR+ +   I+ ++K  N K      N K    LQ F+   + ++   AA+I     + L+ +NIW D  ++NVI+  C     K+ V ALKFFL K  + KD      +   +     R L + +  GKK+   +K L+K +  +K+  K K+ +          N  AI  + DPQ FAE LL +++  K    +++M ++L+SRL+G H+L L NFY ++  FL  H   +                     P    IA+ F  D  S + + +G+N+I+E+  RCP AM +ELL  L  +  H+DKNV  +ARSL++L+R +NP ML K  +G+PTEA+ +  +         A+G L++  +IPGAE++E EQ +    E+++    + +SD++E  +W+D+  S +E   E+ D  +    EER+  A  +S S + + E+   I+   L K+   A  K+ KR      IEIDSD  E        E ++ R I  + KK K+ +E ++ ++  GR DR++F    ++ NP++S+TN+EK K KN+MM+ +
Sbjct:   88 SLLRVHHTVMDPDQRMTLCKALILLRNKNLISPSVLLELFFELLRCQDKLLRKTLYTHIVTDIKNINAKHK----NNKVNTTLQNFMYTMVRDNNAIAAKISLDVMIELYRRNIWNDAKTVNVISTSCFSKVTKILVAALKFFLGKDEEKKDSDSESEDEGPT----ARDLMVRYSTGKKNTKNKKKLEKAMKVLKKHKKKKRPEV--------FNFSAIHLVHDPQEFAEKLLKQLEASKERFEVKLMHMDLISRLVGIHELFLFNFYPFVQRFLQPHQRGM---------------------PKRMTIANNFVTDRNSGEVMTVGINAIKELTARCPLAMTEELLQDLALYKTHKDKNVSMSARSLIQLFRSLNPEMLQKKFRGKPTEASKEARIH--------AYGELDAKDYIPGAEVLEVEQEKTEEPEEDDGWESASLSDDDENGEWIDVHHSSDEEQQEVADKIQAMPAEERKAKAATVSASRLLSQEDFKKIRLAQLAKEMNNAPGKSVKRKN----IEIDSDEEE-----RSGELLSLRDIEHLHKKPKSDKETRLATVMAGRTDRKEFVRKKSKMNPHASSTNKEKKKNKNFMMMRY 640

[Close]

BLAST of Protein SDA1 vs. Ensembl Xenopus
Match: sdad1 (SDA1 domain containing 1 [Source:NCBI gene;Acc:100124509])

HSP 1 Score: 218.394 bits (555), Expect = 4.629e-61
Identity = 193/607 (31.80%), Postives = 318/607 (52.39%), Query Frame = 2

Query:  230 SFIKVYHS----SYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEE---EMPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            S ++V+H+      R+ + K L+ L NKN++      E    L+ C+DK LR+ +   I+ ++K  N K      N K    LQ F+   + ++   AA+I     + L+ +NIW D  ++NVI+  C     K+ V ALKFFL K  + KD      +   +     R L + +  GKK+   +K L+K +  +K+  K K+ +          N  AI  + DPQ FAE LL +++  K    +++M ++L+SRL+G H+L L NFY ++  FL  H   +                     P    IA+ F  D  S + + +G+N+I+E+  RCP AM +ELL  L  +  H+DKNV  +ARSL++L+R +NP ML K  +G+PTEA+ +  +         A+G L++  +IPGAE++E EQ +    E+++    + +SD++E  +W+D+  S +E   E+ D  +    EER+  A  +S S + + E+   I+   L K+   A  K+ KR      IEIDSD  E        E ++ R I  + KK K+ +E ++ ++  GR DR++F    ++ NP++S+TN+EK K KN+MM+ +
Sbjct:   83 SLLRVHHTVMDPDQRMTLCKALILLRNKNLISPSVLLELFFELLRCQDKLLRKTLYTHIVTDIKNINAKHK----NNKVNTTLQNFMYTMVRDNNAIAAKISLDVMIELYRRNIWNDAKTVNVISTSCFSKVTKILVAALKFFLGKDEEKKDSDSESEDEGPT----ARDLMVRYSTGKKNTKNKKKLEKAMKVLKKHKKKKRPEV--------FNFSAIHLVHDPQEFAEKLLKQLEASKERFEVKLMHMDLISRLVGIHELFLFNFYPFVQRFLQPHQRGM---------------------PKRMTIANNFVTDRNSGEVMTVGINAIKELTARCPLAMTEELLQDLALYKTHKDKNVSMSARSLIQLFRSLNPEMLQKKFRGKPTEASKEARIH--------AYGELDAKDYIPGAEVLEVEQEKTEEPEEDDGWESASLSDDDENGEWIDVHHSSDEEQQEVADKIQAMPAEERKAKAATVSASRLLSQEDFKKIRLAQLAKEMNNAPGKSVKRKN----IEIDSDEEE-----RSGELLSLRDIEHLHKKPKSDKETRLATVMAGRTDRKEFVRKKSKMNPHASSTNKEKKKNKNFMMMRY 635

[Close]

BLAST of Protein SDA1 vs. Ensembl Mouse
Match: Sdad1 (SDA1 domain containing 1 [Source:MGI Symbol;Acc:MGI:2140779])

HSP 1 Score: 252.677 bits (644), Expect = 1.530e-73
Identity = 207/592 (34.97%), Postives = 328/592 (55.41%), Query Frame = 2

Query:  260 RIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAAR----IFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEEEMPDPKELRDP---EERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            R+   K L+ L NKN++      E    L+ C DK LR+ +   I+ ++K  N K      N K  ++LQ F+   + +    AA+    + + L+ +NIW D  ++NVI   C     K+ V AL FFL K  + K DSDSESE +       R L + +  GKK    +K L+K +  +K+K K K +           N  AI  + DPQ FAE LL +++  K    ++MM++ L+SRL+G H+L L NFY ++  FL  H  +VT +L++AAQASH  V P+ IQ ++  +A+ F  D  S + + +G+N+I+EI  RCP AM +ELL  L ++  H+DKNV+ +AR+L+ L+R +NP ML K  +G+PTEA+++  +Q         +G L++  +IPGAE++E E+ +    +++ +ES S   +EEE  +WVD+  S +EE        D    EER+  A  +S S + T ++   I+   +KK+   A     +AQ    +EIDSD           E ++ R I ++ KK K+ +E ++ +   GR DR++F     + NP SS+TN+EK K+KN+MM+ +
Sbjct:   97 RMTFCKALILLRNKNLINPSSLLELFFELLRCHDKLLRKTLYTHIVTDIKNINAKHK----NNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKITKILVAALTFFLGKDEEEKQDSDSESEEDGPT---ARDLLVQYATGKKGSKNKKKLEKAMKVLKQKKKKKPEV---------FNFSAIHLIHDPQDFAEKLLKQLESCKERFEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLVTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARIQ--------EYGELDAKDYIPGAEVLELEKGDNTEDDEDGWESASLSEEEEEDGEWVDVHHSSDEEQQAIATKLDSMPMEERKAKAAAISTSRVLTQDDFQKIRMAQMKKEMDAAP---GKAQKRKYLEIDSDE------ESRGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFVRKKTKINPFSSSTNKEKKKQKNFMMMRY 655

[Close]

BLAST of Protein SDA1 vs. Ensembl Mouse
Match: Sdad1 (SDA1 domain containing 1 [Source:MGI Symbol;Acc:MGI:2140779])

HSP 1 Score: 252.677 bits (644), Expect = 1.593e-73
Identity = 207/592 (34.97%), Postives = 329/592 (55.57%), Query Frame = 2

Query:  260 RIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAAR----IFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEEEMPDPKELRDP---EERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            R+   K L+ L NKN++      E    L+ C DK LR+ +   I+ ++K  N K      N K  ++LQ F+   + +    AA+    + + L+ +NIW D  ++NVI   C     K+ V AL FFL K  + K DSDSESE +       R L + +  GKK    +K L+K +  +K++ K KK +          N  AI  + DPQ FAE LL +++  K    ++MM++ L+SRL+G H+L L NFY ++  FL  H  +VT +L++AAQASH  V P+ IQ ++  +A+ F  D  S + + +G+N+I+EI  RCP AM +ELL  L ++  H+DKNV+ +AR+L+ L+R +NP ML K  +G+PTEA+++  +Q         +G L++  +IPGAE++E E+ +    +++ +ES S   +EEE  +WVD+  S +EE        D    EER+  A  +S S + T ++   I+   +KK+   A     +AQ    +EIDSD           E ++ R I ++ KK K+ +E ++ +   GR DR++F     + NP SS+TN+EK K+KN+MM+ +
Sbjct:   97 RMTFCKALILLRNKNLINPSSLLELFFELLRCHDKLLRKTLYTHIVTDIKNINAKHK----NNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKITKILVAALTFFLGKDEEEKQDSDSESEEDGPT---ARDLLVQYATGKKGSKNKKKLEKAMKVLKKQKKKKKPEV--------FNFSAIHLIHDPQDFAEKLLKQLESCKERFEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLVTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARIQ--------EYGELDAKDYIPGAEVLELEKGDNTEDDEDGWESASLSEEEEEDGEWVDVHHSSDEEQQAIATKLDSMPMEERKAKAAAISTSRVLTQDDFQKIRMAQMKKEMDAAP---GKAQKRKYLEIDSDE------ESRGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFVRKKTKINPFSSSTNKEKKKQKNFMMMRY 656

[Close]

BLAST of Protein SDA1 vs. UniProt/SwissProt
Match: sp|Q9NVU7|SDA1_HUMAN (Protein SDA1 homolog OS=Homo sapiens OX=9606 GN=SDAD1 PE=1 SV=3)

HSP 1 Score: 270.011 bits (689), Expect = 3.449e-79
Identity = 215/594 (36.20%), Postives = 340/594 (57.24%), Query Frame = 2

Query:  260 RIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAAR----IFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYE-DWVDIQQ-SDEEEMPDPKELRD-P-EERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            R+   K L+ L NKN++      E    L  C DK LR+ +   I+ ++K  N K      N K  ++LQ F+   + +    AA+    + + L+ +NIW D  ++NVI   C     K+ V AL FFL K    K DSDSESE +       R L + +  GKKS   +K L+K +  +K++ K KK +          N  AI  + DPQ FAE LL +++  K    ++MM++ L+SRL+G H+L L NFY ++  FL  H  +VT +L++AAQASH  V P+ IQ ++  +A+ F  D  S + + +G+N+I+EI  RCP AM +ELL  L ++  H+DKNV+ +AR+L+ L+R +NP ML K  +G+PTEA+++  VQ         +G L++  +IPGAE++E E+ E    +++ +ES S +S+EE+ + +W+D+Q  SDEE+    K+L   P EER+  A  +S S + T E+   I+   ++K+   A  K++KR      IEIDSD     +P    E ++ R I ++ KK K+ +E ++ +   G+ DR++F     + NP SS+TN+EK K+KN+MM+ +
Sbjct:   97 RMTFCKALILLRNKNLINPSSLLELFFELFRCHDKLLRKTLYTHIVTDIKNINAKHK----NNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEDEKQDSDSESEDDGPT---ARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVF--------NFSAIHLIHDPQDFAEKLLKQLECCKERFEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQ--------EYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTS-LSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKY----IEIDSDE----EPR--GELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRY 656

[Close]

BLAST of Protein SDA1 vs. UniProt/SwissProt
Match: sp|A5D7C2|SDA1_BOVIN (Protein SDA1 homolog OS=Bos taurus OX=9913 GN=SDAD1 PE=2 SV=1)

HSP 1 Score: 266.929 bits (681), Expect = 6.187e-78
Identity = 212/593 (35.75%), Postives = 332/593 (55.99%), Query Frame = 2

Query:  260 RIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYE-DWVDIQQSDEEEMPDPKELRDP---EERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            R+   K L+ L NKN++      E    L+ C DK LR+ +   I+ ++K  N K      N K  ++LQ F+   + +    AA+I     + L+ +NIW D  ++NVI   C     K+ V AL FFL K  + K DSDSESE E       R L + +  GKKS   +K L+K +  + +  K KK +          N  AI  + DPQ FAE LL +++  K    ++MM++ L+SRL+G H+L L NFY ++  FL  H  +VT +L++AAQASH  V P+ IQ ++  +A+ F  D  S + + +G+N+I+EI  RCP AM +ELL  L ++  H+DKNV+ +AR+L++L+R +NP ML K  +G+PTEA+++  VQ         +G L++  +IPGAEI+E E  EE A+ DE+    + +SDE + + +WVD+  S +EE  +  E  +    EER+  A  +S S + + E+   I+   ++K+   A     +AQ    IEIDSD           E ++ R I ++ KK K+ +E ++ +   G+ DR++F     + NP SS+TN+EK K+KN+MM+ +
Sbjct:   97 RMTFCKALILLRNKNLINPSSLLELFFELLRCHDKLLRKTLYTHIVTDIKNINAKHK----NNKVNIVLQNFMYTMLRDSNATAAKISLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEEEKQDSDSESEDEGPT---ARDLLVQYATGKKSSKNKKKLEKAMKVLTKHKKKKKPEV--------FNFSAIHLIHDPQDFAEKLLKQLESSKERFEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIQLFRTLNPQMLQKKFRGKPTEASIEARVQ--------EYGELDAKDYIPGAEILEVENEEENAEGDEDGWESASLSDEADSDGEWVDVHHSSDEEQKEISEKLNSMPLEERKAKAAAVSTSRVLSQEDFQKIRMAQMRKELDAAP---GKAQKRKYIEIDSDEER------RGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKMNPFSSSTNKEKKKQKNFMMMRY 657

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BLAST of Protein SDA1 vs. UniProt/SwissProt
Match: sp|Q6NV26|SDA1_DANRE (Protein SDA1 homolog OS=Danio rerio OX=7955 GN=sdad1 PE=2 SV=1)

HSP 1 Score: 258.455 bits (659), Expect = 6.140e-75
Identity = 202/636 (31.76%), Postives = 330/636 (51.89%), Query Frame = 2

Query:  125 EFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMKKAP--IHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEEEMPDPKELRD--PEERRKLAEEM-SYSHIFT-DXXXXXXXXXXXXXXXXGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMV 2002
            E V+FL+     V H     +  F   + +++  +++  V  S  R+   K L+ L NK++V           L+ C DK LR+ +   I+ ++K  N K      N K    LQ F+   + +    AA+I     V L+ +NIW D  ++NVI   C     K+ V  LKFFL K    K D DSESE E S     R L + +  GKK+   +K L+K             KK          N  AI  + DPQ F+E LL +++ +     +++MM+EL+SRL+G H+L L NFY ++  FL  H  +VT +L+ AAQ+SH+ V P+ I+PV+  IA+ F  D  S + + +G+N+I+E+  RCP +M ++LL  L ++  H+DKNV+ +AR L++L+R++NP ML +  +GRPTE++ +  +          +G L +  +IP       E  +   +EDE+    + +SD++E  +WV++  S +++  +  E     PEE RK    M S S + T D+        + K+      K +KR   D++ E   + GE++         + R I ++ KK K+ +E ++ +   GR DR++F     + NP +ST+N+EK +KKN+MM+
Sbjct:   58 ELVMFLA----QVGHCYLEELSDFPQQLTDLL--LNYHTVLESDLRMTFCKALIMLRNKDLVSPTSLLGLFFELLRCHDKLLRKTLYTHIVTDIKNINAKHK----NNKMNTTLQNFMYTMLRDSNPIAAKISLDVMVELYRRNIWNDAKTVNVITTACFSKVTKILVAGLKFFLGKDEDEKKDDDSESEDEGST---ARDLMMRYSTGKKTSKNKKKLEK--------AMKVLKKHKKKKKVEVFNFSAIHLIHDPQDFSEKLLKQLESSNERFEVKIMMMELISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLCAAQSSHQLVPPEIIEPVIMTIANNFVTDRNSGEVMTVGINAIKEVVARCPLSMSEDLLQDLTQYKSHKDKNVVMSARGLIQLFRDLNPKMLTRKDRGRPTESSKEAKIH--------KYGELEAKDYIP--GAEVLEAEKAEDEEDEDGWESASMSDDDEDGEWVNVHHSSDDDQAEVAEKLQSIPEEERKAKAAMVSTSRLLTQDDFKKIRVAQMAKEVGNAPGKGQKRKNVDSDEE---ERGELL---------SLRDIERLHKKPKSDKETRLATAMAGRTDRKEFTKKRGKLNPYASTSNKEKKRKKNFMMM 650

[Close]

BLAST of Protein SDA1 vs. UniProt/SwissProt
Match: sp|Q2VPG3|SDA1_XENLA (Protein SDA1 homolog OS=Xenopus laevis OX=8355 GN=sdad1 PE=2 SV=1)

HSP 1 Score: 256.914 bits (655), Expect = 2.939e-74
Identity = 212/593 (35.75%), Postives = 331/593 (55.82%), Query Frame = 2

Query:  260 RIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEE---EMPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            R+ + K L+ L NKN++      E    L+ C+DK LR+ +   I+ ++K  N K      N K    LQ F+   + ++   AA+I     + L+ +NIW D  ++NVI   C     K+ V ALKFFL K    K DSDSESE E       R L + +  GKK+   +K LDK +  +K+  K K+ +          N  AI  + DPQ FAE LL +++  K    +++M ++L+SRL+G H+L L NFY ++  FL  H  +VT +L+YAAQA+H  V P+  Q V+K IA+ F  D  S + + +G+N+I+E+  RCP AM +ELL  L ++  HRDKNV  +AR L++L+R +NP ML K  +G+PTEA+ +  +         A+G L++  +IPGAE++E EQ ++   E+++    + +SD++E  +W+D+  S +E   EM +  +    EER   A  +S S + T E+   I+   L K+   A  K+ KR      IEIDSD  E        E ++ R I  + KK K+ +E ++ ++  GR DR++F     + NP++S+TN+EK K KN+MM+ +
Sbjct:   97 RMTLCKALIMLRNKNLISPSVLLELFFELLRCQDKLLRKTLYTHIVTDIKNINAKHK----NNKVNTTLQNFMYTMLRDNNAIAAKISLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALKFFLGKDEDEKKDSDSESEDEGPT---ARDLMVRYSTGKKNTKNKKKLDKAMKVLKKHKKKKRPEV--------FNFSAIHLVHDPQEFAEKLLKQLEASKERFEVKLMHMDLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLYAAQATHHLVPPEISQSVLKTIANNFVTDRNSGEVMTVGINAIKEVTARCPLAMTEELLQDLAQYKTHRDKNVSMSARGLIQLFRSLNPDMLQKKFRGKPTEASKEARIH--------AYGELDAKDYIPGAEVLEVEQEKKEEPEEDDGWESASLSDDDEDGEWIDVHHSSDEEQQEMAEKIQAMPTEERIAKAATVSGSRLLTQEDFKKIRLAQLAKEMNNAPGKSMKRKN----IEIDSDEEE-----RSGELLSLRDIEHLHKKPKSDKETRLATVLAGRTDRKEFVRKKTKMNPHASSTNKEKKKNKNFMMMRY 657

[Close]

BLAST of Protein SDA1 vs. UniProt/SwissProt
Match: sp|A4IIB1|SDA1_XENTR (Protein SDA1 homolog OS=Xenopus tropicalis OX=8364 GN=sdad1 PE=2 SV=1)

HSP 1 Score: 256.914 bits (655), Expect = 3.031e-74
Identity = 212/607 (34.93%), Postives = 341/607 (56.18%), Query Frame = 2

Query:  230 SFIKVYHS----SYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEE---EMPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSF 2008
            S ++V+H+      R+ + K L+ L NKN++      E    L+ C+DK LR+ +   I+ ++K  N K      N K    LQ F+   + ++   AA+I     + L+ +NIW D  ++NVI+  C     K+ V ALKFFL K  + K DSDSESE E       R L + +  GKK+   +K L+K +  +K+  K K+ +          N  AI  + DPQ FAE LL +++  K    +++M ++L+SRL+G H+L L NFY ++  FL  H  +VT +L+YAAQA+H  V P+  Q V++ IA+ F  D  S + + +G+N+I+E+  RCP AM +ELL  L  +  H+DKNV  +ARSL++L+R +NP ML K  +G+PTEA+ +  +         A+G L++  +IPGAE++E EQ +    E+++    + +SD++E  +W+D+  S +E   E+ D  +    EER+  A  +S S + + E+   I+   L K+   A  K+ KR      IEIDSD  E        E ++ R I  + KK K+ +E ++ ++  GR DR++F    ++ NP++S+TN+EK K KN+MM+ +
Sbjct:   83 SLLRVHHTVMDPDQRMTLCKALILLRNKNLISPSVLLELFFELLRCQDKLLRKTLYTHIVTDIKNINAKHK----NNKVNTTLQNFMYTMVRDNNAIAAKISLDVMIELYRRNIWNDAKTVNVISTSCFSKVTKILVAALKFFLGKDEEEKKDSDSESEDEGPT---ARDLMVRYSTGKKNTKNKKKLEKAMKVLKKHKKKKRPEV--------FNFSAIHLVHDPQEFAEKLLKQLEASKERFEVKLMHMDLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLYAAQATHHLVPPEISQSVLRTIANNFVTDRNSGEVMTVGINAIKELTARCPLAMTEELLQDLALYKTHKDKNVSMSARSLIQLFRSLNPEMLQKKFRGKPTEASKEARIH--------AYGELDAKDYIPGAEVLEVEQEKTEEPEEDDGWESASLSDDDEDGEWIDVHHSSDEEQQEVADKIQAMPAEERKAKAATVSASRLLSQEDFKKIRLAQLAKEMNNAPGKSVKRKN----IEIDSDEEE-----RSGELLSLRDIEHLHKKPKSDKETRLATVMAGRTDRKEFVRKKSKMNPHASSTNKEKKKNKNFMMMRY 657

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BLAST of Protein SDA1 vs. TrEMBL
Match: A0A172RVY2 (Protein SDA1 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=SDAD1 PE=2 SV=2)

HSP 1 Score: 1193.72 bits (3087), Expect = 0.000e+0
Identity = 688/690 (99.71%), Postives = 689/690 (99.86%), Query Frame = 2

Query:   32 MKFQADLEKVEEDLNEFQTEVASIGTRSVKKEFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMKKAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEEEMPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSFXXXXXXXXXXXXXXXXXXXEHILKKAKFMRQ 2101
            MKFQADLEKVEEDLNEFQTEVASIGTRSVKKEFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNI+PSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKDDSDSESETETSKLDKIRKLKLAHRVGKKSKARQKHLDKELSNIKRKNKSKKKKDNIDILSLECNVLAIQQLRDPQLFAESLLAKMKKAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNI TADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPGAEIIEKEQAEEGAQEDEEYESCSDISDEEEYEDWVDIQQSDEEEMPDPKELRDPEERRKLAEEMSYSHIFTDEEHLAIKKHLLKKKEIGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSFKKKAKQQKLSLKQKNKLLQEHILKKAKFMRQ
Sbjct:    1 MKFQADLEKVEEDLNEFQTEVASIGTRSVKKEFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIIPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKDDSDSESETETSKLDKIRKLKLAHRVGKKSKARQKHLDKELSNIKRKNKSKKKKDNIDILSLECNVLAIQQLRDPQLFAESLLAKMKKAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIRTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPGAEIIEKEQAEEGAQEDEEYESCSDISDEEEYEDWVDIQQSDEEEMPDPKELRDPEERRKLAEEMSYSHIFTDEEHLAIKKHLLKKKEIGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSFKKKAKQQKLSLKQKNKLLQEHILKKAKFMRQ 690

[Close]

BLAST of Protein SDA1 vs. TrEMBL
Match: A0A3Q0KJP0 (Protein SDA1 OS=Schistosoma mansoni OX=6183 PE=3 SV=1)

HSP 1 Score: 346.28 bits (887), Expect = 1.314e-104
Identity = 241/729 (33.06%), Postives = 395/729 (54.18%), Query Frame = 2

Query:   17 LHQNIMKFQADLEKVEEDLNEFQTEVASIGTRSVKK--EFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMKKAP--IHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXX---------------------------------XSCSDISDEEEYEDWVDIQQSDEEE----------------MPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGASKNRKRAQ-----------ADTEIEIDSDTGEII---DPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMV 2002
            L ++ + ++ D E+  E+ +  +   +S  ++ + +  E + FLS      V      +  FST +++ +   SF    H   R+   +  M+L  KN++P+ +A +    L  C DK++R+ + +F+++++K+ N      + N      L K IK++    A  A  I + LF KN+W D  + NVIAD CL  + KV V A++FFL K+  + +   S      ++  KI++L+L HRVG K+K RQK L++ + ++ ++ + K KK          N  A+  L DPQ FAE L  K+++      IR+++L+L+SRLIG +KL L+NFY +I  FL     +VT+LL+++AQASH+ V PD ++P++++IAD F  +  S + IA+GLNS+REIC+RCP+A+  +LL+ L+++  +R+KNV++AARS++RLYR+INP +LP+   GR TE+ +DV        +   +G   + + IPGAEI+     +   ++ E                                   E+CSD   +E   +WV++  S EE+                +P  K   DP   ++ A E++ S IFT EE  A++K+   K++  AS +  R +            DT+ E  ++TG  I   D S+    V+   IT++ K+   T+ ++MESI++GRI REK+GF VNR N  +STTNREK K K + MV
Sbjct:   13 LTRDPLSYRTDFEEQLENFSTLKQSFSSAPSQYISRLEELLSFLS----QAVRYYPEHVADFSTSVIQTLLSRSF--GMHPEMRMGFLRAFMRLRTKNLIPATQAVDIAFKLYRCRDKQVRKTLRHFLVSDIKRMNKCQKQTKANAVILSFLSKMIKDNSSTVAREAVLILLCLFKKNVWNDARTANVIADSCLMGNKKVYVPAIQFFLGKSKALDEMETSSDSESDNEESKIKQLRLGHRVGVKTKGRQKRLERSIKHVNKEKERKIKKRTELT-----NFHALNMLHDPQTFAEKLFRKLERCSDRFEIRLLILDLISRLIGLNKLVLLNFYPFIQRFLRPQQREVTHLLLFSAQASHDQVPPDVMEPLIRVIADNFITERASSEAIAVGLNSVREICLRCPYAVTKDLLSDLIQYRSYRNKNVVAAARSIIRLYRQINPELLPRKECGRLTESQLDVIKYDLPQDVAINYGQCTTSSTIPGAEIVVLASEKLNNKKKESSEKSNQSLDCSEKYSNNEKNDSSESCSEIQEFEDETCSDSETDESDGEWVNLSNSSEEDDEQDNVDIEMDECNVNVPSKKTKIDPTVLKEKAFEIATSRIFTQEEFEAMRKYQQTKQKRFASYSSLRNKHQIDNSDSYFIVDTDDEDGTNTGVGIQNKDGSL-GNLVSMSAITRLVKRPHQTKADRMESIEEGRIGREKYGFKVNRLNAYASTTNREKLKNKTFQMV 729

[Close]

BLAST of Protein SDA1 vs. TrEMBL
Match: H2KR58 (Protein SDA1 (Fragment) OS=Clonorchis sinensis OX=79923 GN=CLF_105541 PE=3 SV=1)

HSP 1 Score: 336.65 bits (862), Expect = 8.412e-102
Identity = 230/669 (34.38%), Postives = 378/669 (56.50%), Query Frame = 2

Query:  161 VVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFL--NKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMKKAP--IHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDA-ARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSD----ISDEEEYE--------DWVDIQQSDEE----------------------EMP-----DPKELRD-------PEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA---SKNRKRAQADTE-IEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMV 2002
            VVH     ++ FS+ +L+ +   SF    + + R+   K  M+L  ++++P  +A +    L  C+DK++R+ + NF+++++K+ N +    ++N   +  L K +K++    A  A  + + LF KN+W D  + N+IA+ CL    KV   A++FFL  +KT   KD           K  KIR+L+L HRVG K+K RQK L++ + +I +    K  K          +  AI  L DPQ FAE L  K++       IR+++L+L++RLIG HKL ++N Y +I  FL  H  +VT LL++ AQASH+ V PD ++PV++ IAD F  +  S + IA+GLN++REIC RCP+ +  +LL+ L+++  +++KNV+++ARSL+RLYREINP+ LP+  +GRPTEA ++  ++G   + L  +FG   +  F+PGAE +   +        E+  +       I D++E +        + VD   +DE+                      ++P     D  E+ D       P E    A E++ S IFT EE  A++++ L K++  A   S+N+++A+ D+E +EIDS+  E       S+ VT   IT++ K+ + ++ E++E+I+DGR  REK+G+ VNR NP++STTNREK+K K + M+
Sbjct:    1 VVHFYPDYVEGFSSGVLQTLLSRSF--GMNPTMRMAFMKAFMRLKTRDLIPLDKAIDIAFKLHRCQDKQVRQTMRNFVVHDIKRLNLRQKMHKVNSLVQSHLAKLLKDNNPTVAREAVFVLLRLFRKNVWNDARTANLIAEACLAKRKKVYAPAVRFFLGQDKTNNEKDSDSESEPDTH-KETKIRQLRLGHRVGCKTKNRQKRLERSIEHINKVEARKAAKGTNL-----AHFAAINLLHDPQAFAERLFRKLEHCSDRFEIRLLLLDLVTRLIGLHKLLVLNLYPFIQRFLRPHQREVTRLLLFTAQASHDEVPPDVMEPVIRTIADNFVTERASSEAIAVGLNAVREICARCPYGISQDLLSDLVQYRTYKNKNVVASARSLIRLYREINPSALPRKERGRPTEAQLETMIEGQTFSGLALSFGQTTAAKFVPGAEALVLAETLAKQSRREDRNNSGSSKRMIKDDKETKNTEERLNAEGVDADANDEDSEACGEVNKSSRITQKKDDGWIDVPQSSDDDETEVSDTAKPKIDPSELASKALEIASSRIFTQEEFEAMRRYQLNKQKRFAAMGSRNKRKAEDDSEFLEIDSEEDEADGDKANSQLVTMSAITRLVKRPRQSKAERLEAIQDGRAGREKYGYKVNRMNPHASTTNREKSKGKTFQMI 661

[Close]

BLAST of Protein SDA1 vs. TrEMBL
Match: G4LWB2 (Protein SDA1 OS=Schistosoma mansoni OX=6183 GN=Smp_098980 PE=3 SV=1)

HSP 1 Score: 337.421 bits (864), Expect = 4.175e-101
Identity = 241/733 (32.88%), Postives = 392/733 (53.48%), Query Frame = 2

Query:   17 LHQNIMKFQADLEKVEEDLNEFQTEVASIGTRSVKK--EFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKL----DKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMKKAP--IHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXX---------------------------------XSCSDISDEEEYEDWVDIQQSDEEE----------------MPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGASKNRKRAQ-----------ADTEIEIDSDTGEII---DPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMV 2002
            L ++ + ++ D E   E+ +  +   +S  ++ + +  E + FLS      V      +  FST +++ +   SF    H   R+   +  M+L  KN++P+ +A +    L  C DK++R+ + +F+++++K+ N      + N      L K IK++    A  A  I + LF KN+W D  + NVIAD CL  + KV V A++FFL K+  + +   S              KI++L+L HRVG K+K RQK L++ + ++ ++ + K KK          N  A+  L DPQ FAE L  K+++      IR+++L+L+SRLIG +KL L+NFY +I  FL     +VT+LL+++AQASH+ V PD ++P++++IAD F  +  S + IA+GLNS+REIC+RCP+A+  +LL+ L+++  +R+KNV++AARS++RLYR+INP +LP+   GR TE+ +DV        +   +G   + + IPGAEI+     +   ++ E                                   E+CSD   +E   +WV++  S EE+                +P  K   DP   ++ A E++ S IFT EE  A++K+   K++  AS +  R +            DT+ E  ++TG  I   D S+    V+   IT++ K+   T+ ++MESI++GRI REK+GF VNR N  +STTNREK K K + MV
Sbjct:   13 LTRDPLSYRTDFEGQLENFSTLKQSFSSAPSQYISRLEELLSFLS----QAVRYYPEHVADFSTSVIQTLLSRSF--GMHPEMRMGFLRAFMRLRTKNLIPATQAVDIAFKLYRCRDKQVRKTLRHFLVSDIKRMNKCQKQTKANAVILSFLSKMIKDNSSTVAREAVLILLCLFKKNVWNDARTANVIADSCLMGNKKVYVPAIQFFLGKSKALDEMETSSDSESDVSRVNEESKIKQLRLGHRVGVKTKGRQKRLERSIKHVNKEKERKIKKRTELT-----NFHALNMLHDPQTFAEKLFRKLERCSDRFEIRLLILDLISRLIGLNKLVLLNFYPFIQRFLRPQQREVTHLLLFSAQASHDQVPPD-MEPLIRVIADNFITERASSEAIAVGLNSVREICLRCPYAVTKDLLSDLIQYRSYRNKNVVAAARSIIRLYRQINPELLPRKECGRLTESQLDVIKYDLPQDVAINYGQCTTSSTIPGAEIVVLASEKLNNKKKESSEKSNQSLDCSEKYSNNEKNDSSESCSEIQEFEDETCSDSETDESDGEWVNLSNSSEEDDEQDNVDIEMDERNVNVPSKKTKIDPTVLKEKAFEIATSRIFTQEEFEAMRKYQQTKQKRFASYSSLRNKHQIDNSDSYFIVDTDDEDGTNTGVGIQNKDGSL-GNLVSMSAITRLVKRPHQTKADRMESIEEGRIGREKYGFKVNRLNAYASTTNREKLKNKTFQMV 732

[Close]

BLAST of Protein SDA1 vs. TrEMBL
Match: A0A4Z2D2C8 (Protein SDA1 OS=Schistosoma japonicum OX=6182 GN=EWB00_005191 PE=3 SV=1)

HSP 1 Score: 324.324 bits (830), Expect = 5.076e-97
Identity = 224/650 (34.46%), Postives = 361/650 (55.54%), Query Frame = 2

Query:  248 HSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMKKAP--IHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXX---------------------XXXSCSDISD-----------EEEYEDWVDIQQSDEE-----------------EMPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGASKN--RKRAQADTEIEI----DSDTGEII--------DPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMV 2002
            H   R+   +  M++  +N++ + +A +    L  C DK++R+ + +F+++++K+ N      + N      L K IK++    A  A    + LF KN+W D  + NVIAD CL ++ KV V A++FFL K+  + +   S      ++  KI++L+L HRVG K+K RQK LD+ + ++ ++ + K KK +        N  A+  L DPQ FAE L  K+++      IR+++L+L+SRLIG +KL L+NFY +I  FL     +VT+LL+++AQASH+ V PD ++P++++IAD F  +  S + IA+GLNS+REIC RCP+A+  +LL+ L+++  +R+KNV++AARS++RLYR+INP MLP+   GR TE+ +DV        +   FG   + + IPGAEI+     +  +++ E                       +SCSD  D           +E   +WVD+  S EE                 E+   K   DP   ++ A E++ S IFT EE  A++K+   K++   S +  R + ++D    I    D + GE I        D S+    V+   IT++ K+ + T+ E+ME+I++GR+ REK+GF VNR N ++STTNREK K K + M+
Sbjct:    2 HPEMRMAFLRAFMRIRTRNLISATQAVDVAFKLHRCRDKQVRKTLRHFLVSDIKRMNKSQKQTKANAIILSFLSKMIKDNSSTVAREAVVTLLCLFKKNVWNDARTANVIADSCLMSNKKVYVPAIQFFLGKSKALNEMETSSDSESENEETKIKQLRLRHRVGIKTKGRQKRLDRSIKHVNKEKERKIKKRSELT-----NFHALNMLHDPQSFAEKLFRKLERCSDRFEIRILILDLISRLIGLNKLILLNFYPFIQRFLRPQQREVTHLLLFSAQASHDQVPPDVMEPLIRVIADNFITERASSEAIAVGLNSVREICARCPYAVTKDLLSDLIQYRSYRNKNVVAAARSIIRLYRQINPEMLPRKECGRLTESQLDVLKYDLPQDVAINFGQSTTSSSIPGAEIVVLASEKLNSKKKESCKMLDKNSDNSKECNNEAIDTRKSCSDDEDSGEKICINNESDESDSEWVDLSHSSEEEDEQNNEDIVMDECNNIEITTKKISMDPSVLKEKALEIATSRIFTQEEFEAMRKYQQTKQKRFVSYSSLRNKHKSDDAYFIVNSDDDEDGENITGVGIQNKDGSL-GNLVSMSAITRLVKRPRQTKAERMENIEEGRVGREKYGFKVNRLNAHASTTNREKLKNKTFQMI 645

[Close]

BLAST of Protein SDA1 vs. Ensembl Cavefish
Match: sdad1 (SDA1 domain containing 1 [Source:NCBI gene;Acc:286746])

HSP 1 Score: 169.474 bits (428), Expect = 2.258e-44
Identity = 171/571 (29.95%), Postives = 283/571 (49.56%), Query Frame = 2

Query:  320 EAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQS---DEEEMPDPKELRDPEERRKLAEEMSYSHIFT-DXXXXXXXXXXXXXXXXGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMV 2002
            E  E LL   T  + +LR  +   I+ ++K  N K    +LN      LQ F+   + +    AA+I     V L+ +NIW D  ++NVI   C     K+ V ALKFFL K    K DSDS+SE E       R L + +  GKK+   +K L+K +  +K+  K KK +          N  AI  + DPQ FAE LL +++  K    +++M++EL+SRL+G H+L L NFY ++  FL  H                ++ +P  I P++  IA+ F  D  S + + +G+N+I+E+  RCP +M ++LL  L ++  H+DK                              +A+ +  +Q         +G L +  +IPGAE++E E+  +G ++++ +ES S +S++++  +WV++  S   D+EE+ +       EER+  A  +S S + T D+        + K  +    K +KR QAD E E +             E ++ R I ++ KK K+ +E ++ +   GR DR++F    ++ NP +ST+N+EK K KN+MM+
Sbjct:   80 ELTELLLNHHTVLESDLRMTLYTHIVTDIKNINAKHKNNKLN----TTLQNFMYTMLRDSNPIAAKISLDVMVELYQRNIWNDAKTVNVITTACFSKVTKILVAALKFFLGKDEDEKKDSDSDSEDEGP---SARDLMVRYSTGKKTSKNKKKLEKAMKVLKKHKKKKKAEV--------FNFSAIHLIHDPQDFAEKLLKQLESSKERFEVKIMLMELISRLVGIHELFLFNFYPFVQRFLQPHQRG-------------KYPTPAIISPMIMTIANNFVTDRNSGEVMTVGINAIKEVVARCPLSMTEDLLQDLTQYKSHKDK------------------------------KASTEAKIQ--------QYGELEAKDYIPGAEVLEVEEQPKGEEDEDGWESAS-MSEDDDDGEWVNVHHSSDEDQEEVAEKLNSIPAEERKSKAAAVSASRLLTQDDFKKIHLAQMAKDMKSAPGKGQKRKQADREEETER-----------GELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFVKKRSKLNPFASTSNKEKRKTKNFMMM 572

[Close]

BLAST of Protein SDA1 vs. Ensembl Cavefish
Match: sdad1 (SDA1 domain containing 1 [Source:NCBI gene;Acc:286746])

HSP 1 Score: 163.31 bits (412), Expect = 2.232e-41
Identity = 125/352 (35.51%), Postives = 192/352 (54.55%), Query Frame = 2

Query:  242 VYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARI----FVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMK--KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKN 1279
            V  S  R+   K L+ L NK+++      E    L+ C DK LR+ +   I+ ++K  N K      N K    LQ F+   + +    AA+I     V L+ +NIW D  ++NVI   C     K+ V ALKFFL K    K DSDS+SE E       R L + +  GKK+   +K L+K +  +K+  K KK +          N  AI  + DPQ FAE LL +++  K    +++M++EL+SRL+G H+L L NFY ++  FL  H  +VT +L+ +AQASH+ V P+ I P++  IA+ F  D  S + + +G+N+I+E+  RCP +M ++LL  L ++  H+DK+
Sbjct:   91 VLESDLRMTFCKALIMLRNKDLIDPASLLELFFELLRCHDKLLRQTLYTHIVTDIKNINAKHK----NNKLNTTLQNFMYTMLRDSNPIAAKISLDVMVELYQRNIWNDAKTVNVITTACFSKVTKILVAALKFFLGKDEDEKKDSDSDSEDEGPS---ARDLMVRYSTGKKTSKNKKKLEKAMKVLKKHKKKKKAEVF--------NFSAIHLIHDPQDFAEKLLKQLESSKERFEVKIMLMELISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLCSAQASHQLVPPEIISPMIMTIANNFVTDRNSGEVMTVGINAIKEVVARCPLSMTEDLLQDLTQYKSHKDKS 427

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BLAST of Protein SDA1 vs. Ensembl Yeast
Match: SDA1 (Protein required for actin organization and passage through Start; highly conserved nuclear protein; required for actin cytoskeleton organization; plays a critical role in G1 events; binds Nap1p; involved in 60S ribosome biogenesis [Source:SGD;Acc:S000003477])

HSP 1 Score: 169.474 bits (428), Expect = 1.223e-44
Identity = 137/461 (29.72%), Postives = 224/461 (48.59%), Query Frame = 2

Query:  125 EFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPL------------VTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXX-KLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLL-----AKMK-KAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFI 1450
            E V F+S +                 ++LE  K + F        + +I   L  L NK+++ + E  ++L PL            V    KELR+I+   +I+ LK  N      +LNK ++ +    + +   +   +A ++   L+ + IW D  ++ ++    LH   K+ ++ + FFL+   + +++ +  SE E    LD +R      +V KK+  R K L+  +  +K+K K+              N  AI  LRDPQ FAE L       K K K  +  ++ +++LLSRLIG HKL ++  Y++ + +L     DVT ++   AQA H+ V P+ I  +V+ IAD+F  DG++ +  A G+N+IREIC R P A+ + LL  L+E+   + K V  AA+SL+ LYR++ P ML K  +G+     V    +G        FG  NSV  I
Sbjct:   89 ELVGFVSQVCSCFPRETANFPSELKQLLLEHHKSLPF------ELKEKILSCLTMLRNKDVITAEELIQSLFPLLVAYSSHGNSLGVNSHAKELRKIIYTNLISLLKSCNTNGKNQKLNKSTQAVCFNLL-DQPDSQGIWATKLTRELWRRGIWDDSRTVEIMTQAALHQDVKIVMSGVMFFLDADREREENFEENSEDEDGFDLDALRH---KMQVNKKTGRRGKKLENAIKTVKKKKKNGPGAPQGY-----LNFSAIHLLRDPQGFAEKLFKEHLSGKTKNKFDMEQKISLMQLLSRLIGTHKLIVLGIYTFFLKYLTPKQRDVTRIMSACAQACHDLVPPEVINVMVRKIADEFVSDGVANEVAAAGINTIREICSRAPLAIDEILLQDLVEYKGSKAKGVNMAAKSLIALYRDVAPEMLKKKDRGKNAAMEVQEAKKGGKDSKRPQFGADNSVQGI 534

[Close]

BLAST of Protein SDA1 vs. Ensembl Nematostella
Match: SDAD1 (Protein SDA1 homolog [Source:UniProtKB/Swiss-Prot;Acc:A7S6A5])

HSP 1 Score: 187.963 bits (476), Expect = 7.335e-51
Identity = 129/399 (32.33%), Postives = 212/399 (53.13%), Query Frame = 2

Query:  851 NVLAIQQLRDPQLFAESLLAKMKKAP--IHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXX-------XXXSCSDISDEEEYEDWVDIQQSDEEEM----PDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGA-SKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVN-RFNPNSSTTNREKAKKKNYMMV 2002
            N  A+  + DPQ F+E L  +++ +     +R+M++ L+SRLIG H+L + NFY ++  +L  H  +VT LL++ +QASH+ V P+ ++P V+ I + F  +  S + +A+GLN++RE+C RCP  M D LL  L ++   +DK+V+ A++SL++L+R +NP +L K  +G+PTE+  D          P  +  + +  +IPGAE+I    +                 E C D SDE   + W+D+Q S +EE     P  +     E+ +  A  +S   I TDE+   I+   L K+      K RKRA    E +              +E V    I  + KK K  +  ++E++  GR DR K+G     + N ++ T+N+EK +KKN+MM+
Sbjct:  278 NFSALHLINDPQGFSERLFKQLEASTGRFEVRIMLMNLISRLIGVHQLFVFNFYPFLQRYLQPHQREVTKLLMFFSQASHDLVPPEVVEPGVRTIVNNFVTERNSHEVMAVGLNAVREVCQRCPLVMTDTLLQDLAQYKTSKDKSVMMASQSLIQLFRSVNPNLLHKKDRGQPTESREDSK--------PLDYAAVEAKDYIPGAELINYANSTIILLYATLIPDGWETDEGCDDGSDE---DGWIDVQHSSDEEQEDEDPSGENQEGEEDGQTRAARISQMRILTDEDFKKIRMKQLTKEVQPKLGKKRKRATTTEEPQ-----------GSRNELVALENIEGIYKKRKHDKASRLETVIAGRQDRPKYGTKKKAKMNEHAGTSNKEKRRKKNFMMM 654

HSP 2 Score: 68.9366 bits (167), Expect = 4.543e-12
Identity = 41/137 (29.93%), Postives = 66/137 (48.18%), Query Frame = 2

Query:  242 VYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAAR----IFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLN 640
            V  S  R+ + + L+ L NK+++      E    L  C DK LR+++   I+ ++K  N K      N K    LQ F+   + +    AA+    + + L+ +N+W D  ++NVI   C     K+ V ALKFFL 
Sbjct:   97 VMDSDLRMTLCRALILLRNKDLISPTSILELFFELFRCNDKVLRQVLYTHIVTDIKNMNAKHK----NNKVNSTLQNFMYTMLKDSNAVAAKKSLDVLIELYKRNVWKDAKTVNVITTACFSPVPKILVAALKFFLG 229

[Close]

BLAST of Protein SDA1 vs. Planmine SMEST
Match: SMESG000046023.1 (SMESG000046023.1)

HSP 1 Score: 1194.87 bits (3090), Expect = 0.000e+0
Identity = 689/690 (99.86%), Postives = 689/690 (99.86%), Query Frame = 2

Query:   32 MKFQADLEKVEEDLNEFQTEVASIGTRSVKKEFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKXXXXXXXXXXXXKLDKIRKLKLAHRVGKKSKARQKHLDKEXXXXXXXXXXXXXXXXXXXXXXECNVLAIQQLRDPQLFAESLLAKMKKAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPXXXXXXXXXXXXXXXXXXXXXSCSDISDEEEYEDWVDIQQSDEEEMPDPKELRDPEERRKLAEEMSYSHIFTDXXXXXXXXXXXXXXXXGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSFXXXXXXXXXXXXXXXXXXXEHILKKAKFMRQ 2101
            MKFQADLEKVEEDLNEFQTEVASIGTRSVKKEFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKDDSDSESETETSKLDKIRKLKLAHRVGKKSKARQKHLDKELSNIKRKNKSKKKKDNIDILSLECNVLAIQQLRDPQLFAESLLAKMKKAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNI TADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPGAEIIEKEQAEEGAQEDEEYESCSDISDEEEYEDWVDIQQSDEEEMPDPKELRDPEERRKLAEEMSYSHIFTDEEHLAIKKHLLKKKEIGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSFKKKAKQQKLSLKQKNKLLQEHILKKAKFMRQ
Sbjct:    1 MKFQADLEKVEEDLNEFQTEVASIGTRSVKKEFVVFLSALFKNVVHSNETLIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFEALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIKEHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKFFLNKTAKVKDDSDSESETETSKLDKIRKLKLAHRVGKKSKARQKHLDKELSNIKRKNKSKKKKDNIDILSLECNVLAIQQLRDPQLFAESLLAKMKKAPIHIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIRTADVTNLLVYAAQASHEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPDELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVDVGVQGDAARLPTAFGVLNSVAFIPGAEIIEKEQAEEGAQEDEEYESCSDISDEEEYEDWVDIQQSDEEEMPDPKELRDPEERRKLAEEMSYSHIFTDEEHLAIKKHLLKKKEIGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTERVITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAKKKNYMMVSFKKKAKQQKLSLKQKNKLLQEHILKKAKFMRQ 690

The following BLAST results are available for this feature:

BLAST of Protein SDA1 vs. Ensembl Human
BLAST of Protein SDA1 vs. Ensembl Celegans
BLAST of Protein SDA1 vs. Ensembl Fly
BLAST of Protein SDA1 vs. Ensembl Zebrafish
BLAST of Protein SDA1 vs. Ensembl Xenopus
BLAST of Protein SDA1 vs. Ensembl Mouse
BLAST of Protein SDA1 vs. UniProt/SwissProt
BLAST of Protein SDA1 vs. TrEMBL
BLAST of Protein SDA1 vs. Ensembl Cavefish
BLAST of Protein SDA1 vs. Ensembl Sea Lamprey
BLAST of Protein SDA1 vs. Ensembl Yeast
BLAST of Protein SDA1 vs. Ensembl Nematostella
BLAST of Protein SDA1 vs. Ensembl Medaka
BLAST of Protein SDA1 vs. Planmine SMEST

BLAST of Protein SDA1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2


Match Name	E-value	Identity	Description
SDAD1	7.182e-80	36.20	SDA1 domain containing 1 [Source:HGNC Symbol;Acc:H...	[more]
SDAD1	4.281e-74	36.14	SDA1 domain containing 1 [Source:HGNC Symbol;Acc:H...	[more]

BLAST of Protein SDA1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
pro-3	5.720e-57	33.89	pep chromosome:WBcel235:V:19101961:19118412:-1 gen...	[more]

BLAST of Protein SDA1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Mys45A	7.788e-61	33.87	gene:FBgn0033379 transcript:FBtr0088628	[more]

BLAST of Protein SDA1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
sdad1	2.397e-76	31.92	SDA1 domain containing 1 [Source:NCBI gene;Acc:286...	[more]
sdad1	8.198e-12	30.99	SDA1 domain containing 1 [Source:NCBI gene;Acc:286...	[more]

BLAST of Protein SDA1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sdad1	3.647e-75	33.77	SDA1 domain containing 1 [Source:NCBI gene;Acc:100...	[more]
sdad1	4.047e-70	32.13	SDA1 domain containing 1 [Source:NCBI gene;Acc:100...	[more]
sdad1	6.634e-67	32.79	SDA1 domain containing 1 [Source:NCBI gene;Acc:100...	[more]
sdad1	3.971e-61	31.80	SDA1 domain containing 1 [Source:NCBI gene;Acc:100...	[more]
sdad1	4.629e-61	31.80	SDA1 domain containing 1 [Source:NCBI gene;Acc:100...	[more]

BLAST of Protein SDA1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Sdad1	1.530e-73	34.97	SDA1 domain containing 1 [Source:MGI Symbol;Acc:MG...	[more]
Sdad1	1.593e-73	34.97	SDA1 domain containing 1 [Source:MGI Symbol;Acc:MG...	[more]

BLAST of Protein SDA1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9NVU7\|SDA1_HUMAN	3.449e-79	36.20	Protein SDA1 homolog OS=Homo sapiens OX=9606 GN=SD...	[more]
sp\|A5D7C2\|SDA1_BOVIN	6.187e-78	35.75	Protein SDA1 homolog OS=Bos taurus OX=9913 GN=SDAD...	[more]
sp\|Q6NV26\|SDA1_DANRE	6.140e-75	31.76	Protein SDA1 homolog OS=Danio rerio OX=7955 GN=sda...	[more]
sp\|Q2VPG3\|SDA1_XENLA	2.939e-74	35.75	Protein SDA1 homolog OS=Xenopus laevis OX=8355 GN=...	[more]
sp\|A4IIB1\|SDA1_XENTR	3.031e-74	34.93	Protein SDA1 homolog OS=Xenopus tropicalis OX=8364...	[more]

BLAST of Protein SDA1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A172RVY2	0.000e+0	99.71	Protein SDA1 (Fragment) OS=Schmidtea mediterranea ...	[more]
A0A3Q0KJP0	1.314e-104	33.06	Protein SDA1 OS=Schistosoma mansoni OX=6183 PE=3 S...	[more]
H2KR58	8.412e-102	34.38	Protein SDA1 (Fragment) OS=Clonorchis sinensis OX=...	[more]
G4LWB2	4.175e-101	32.88	Protein SDA1 OS=Schistosoma mansoni OX=6183 GN=Smp...	[more]
A0A4Z2D2C8	5.076e-97	34.46	Protein SDA1 OS=Schistosoma japonicum OX=6182 GN=E...	[more]

BLAST of Protein SDA1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
sdad1	2.258e-44	29.95	SDA1 domain containing 1 [Source:NCBI gene;Acc:286...	[more]
sdad1	2.232e-41	35.51	SDA1 domain containing 1 [Source:NCBI gene;Acc:286...	[more]

BLAST of Protein SDA1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Protein SDA1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
SDA1	1.223e-44	29.72	Protein required for actin organization and passag...	[more]

BLAST of Protein SDA1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
SDAD1	7.335e-51	32.33	Protein SDA1 homolog [Source:UniProtKB/Swiss-Prot...	[more]

BLAST of Protein SDA1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Protein SDA1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000046023.1	0.000e+0	99.86	SMESG000046023.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30024098 ID=SMED30024098|Name=Protein SDA1|organism=Schmidtea mediterranea sexual|type=transcript|length=2131bp
GTTTTAATATTAGTTTTTACATCAAAATATCATGAAATTTCAGGCGGATT
TGGAAAAAGTCGAAGAGGATTTAAATGAATTTCAAACTGAAGTTGCATCT
ATAGGTACTCGGTCGGTTAAAAAAGAATTTGTTGTGTTTTTGAGCGCTTT
ATTCAAGAATGTGGTGCACTCCAACGAAACTCTGATTAAAAGATTTTCTA
CAATGATTTTAGAAATAATTAAGCAAGTATCTTTTATAAAAGTTTATCAT
TCGTCCTACAGAATTGAAATTGCTAAAATTCTTATGAAACTTTCCAATAA
AAATATTGTACCATCACTTGAAGCGTTTGAAGCGCTTCTTCCACTTGTTA
CCTGTGAAGATAAGGAATTAAGACGAATCGTAATTAATTTTATAATAAAC
GAACTGAAAAAGAAAAACAATAAATCTAATCCTGTTGAATTAAATAAAAA
ATCGAAGTTGCTTTTACAAAAATTCATAAAAGAACATATAGGAAATCATG
CAAATTTCGCCGCAAGGATATTTGTTTTGTTATTTATAAAAAACATTTGG
ACAGATCAATATTCACTTAACGTTATTGCCGATTGTTGTTTACACAATTC
AGCAAAAGTTAAGGTGACTGCTTTGAAGTTCTTTCTTAATAAAACAGCTA
AAGTAAAAGATGATTCCGATAGTGAATCCGAGACCGAAACGTCGAAGCTC
GACAAAATCAGAAAACTGAAATTAGCCCATCGAGTCGGTAAGAAAAGTAA
AGCTCGACAGAAGCATTTGGATAAAGAGCTGAGTAACATAAAACGAAAGA
ACAAAAGCAAAAAGAAAAAAGACAATATCGATATTCTGTCGCTGGAATGC
AACGTTTTGGCAATCCAACAGCTTCGAGATCCGCAACTATTCGCTGAATC
GTTGCTGGCAAAGATGAAAAAGGCGCCGATCCACATCCGAATGATGATGC
TGGAGTTGCTGTCGAGATTGATCGGCTATCACAAATTGCAATTGGTTAAT
TTCTATTCCTATATCGTTGGGTTTCTCAACATCCACACGGCCGACGTGAC
AAACTTGCTGGTATATGCCGCCCAGGCGAGCCATGAATTCGTGTCACCCG
ATGACATTCAGCCGGTCGTCAAGATGATTGCCGATCAATTCGCGATTGAC
GGGATATCCGAGCAGGGAATCGCGTTGGGATTGAACTCGATCCGTGAGAT
CTGCGTACGGTGTCCCCATGCAATGCCAGATGAGCTGCTGGCACCGTTGC
TAGAGTTCATTAAGCATCGAGACAAAAATGTCATTTCTGCTGCCAGATCT
CTGCTGAGACTGTATCGAGAGATCAATCCCGCTATGTTACCGAAATCATT
GCAAGGCCGACCGACCGAAGCTACAGTTGATGTTGGTGTTCAAGGAGATG
CGGCTCGGTTGCCAACGGCTTTCGGTGTGTTGAATTCGGTGGCGTTCATT
CCCGGGGCAGAAATCATTGAGAAGGAACAAGCAGAGGAAGGGGCCCAGGA
GGACGAGGAATATGAGTCCTGCAGTGACATCAGCGACGAAGAGGAATACG
AAGATTGGGTTGATATTCAGCAGTCGGATGAGGAAGAAATGCCCGACCCG
AAGGAGTTGCGAGACCCGGAAGAAAGACGGAAACTCGCCGAAGAGATGTC
GTATAGCCACATTTTCACTGACGAGGAGCATTTGGCTATCAAAAAGCATC
TACTAAAGAAAAAAGAAATAGGAGCAAGCAAAAACCGAAAGCGGGCACAG
GCGGACACAGAAATCGAGATCGATTCCGATACCGGGGAAATCATCGATCC
GTCTGTACCGTCGGAATTCGTCACGGAACGAGTGATAACGAAAATGTCAA
AGAAACTAAAAGCGACCCGTGAAGAAAAGATGGAAAGCATCAAGGATGGC
CGAATCGATCGAGAGAAATTCGGGTTCAATGTCAACCGGTTCAATCCGAA
TTCCAGCACGACAAATAGAGAAAAGGCGAAGAAAAAGAATTACATGATGG
TCAGTTTTAAAAAGAAAGCCAAACAGCAGAAATTGAGCTTGAAACAGAAA
AATAAACTACTGCAGGAGCATATTTTGAAAAAAGCCAAATTTATGCGTCA
ATAAATATAAATTTGTCTGTAACTCTGCGTT

protein sequence of SMED30024098-orf-1

>SMED30024098-orf-1 ID=SMED30024098-orf-1|Name=SMED30024098-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=691bp
MKFQADLEKVEEDLNEFQTEVASIGTRSVKKEFVVFLSALFKNVVHSNET
LIKRFSTMILEIIKQVSFIKVYHSSYRIEIAKILMKLSNKNIVPSLEAFE
ALLPLVTCEDKELRRIVINFIINELKKKNNKSNPVELNKKSKLLLQKFIK
EHIGNHANFAARIFVLLFIKNIWTDQYSLNVIADCCLHNSAKVKVTALKF
FLNKTAKVKDDSDSESETETSKLDKIRKLKLAHRVGKKSKARQKHLDKEL
SNIKRKNKSKKKKDNIDILSLECNVLAIQQLRDPQLFAESLLAKMKKAPI
HIRMMMLELLSRLIGYHKLQLVNFYSYIVGFLNIHTADVTNLLVYAAQAS
HEFVSPDDIQPVVKMIADQFAIDGISEQGIALGLNSIREICVRCPHAMPD
ELLAPLLEFIKHRDKNVISAARSLLRLYREINPAMLPKSLQGRPTEATVD
VGVQGDAARLPTAFGVLNSVAFIPGAEIIEKEQAEEGAQEDEEYESCSDI
SDEEEYEDWVDIQQSDEEEMPDPKELRDPEERRKLAEEMSYSHIFTDEEH
LAIKKHLLKKKEIGASKNRKRAQADTEIEIDSDTGEIIDPSVPSEFVTER
VITKMSKKLKATREEKMESIKDGRIDREKFGFNVNRFNPNSSTTNREKAK
KKNYMMVSFKKKAKQQKLSLKQKNKLLQEHILKKAKFMRQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000208	testis
PLANA:0000228	male germ cell
PLANA:0000429	neoblast
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR027312	Sda1
IPR007949	SDA1_dom
IPR016024	ARM-type_fold

Vocabulary: **molecular function**
Term	Definition
GO:0005488	binding

Vocabulary: **biological process**
Term	Definition
GO:0000055	ribosomal large subunit export from nucleus
GO:0006810	transport
GO:0015031	protein transport
GO:0030036	actin cytoskeleton organization
GO:0042254	ribosome biogenesis
GO:0042273	ribosomal large subunit biogenesis

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005730	nucleolus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 7..27
None	No IPR available	COILS	Coil	Coil	coord: 243..263
None	No IPR available	COILS	Coil	Coil	coord: 660..680
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 484..516
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 483..529
IPR007949	SDA1 domain	PFAM	PF05285	SDA1	coord: 528..686 e-value: 4.7E-24 score: 85.5 coord: 398..522 e-value: 1.3E-26 score: 93.9
IPR027312	Sda1	PANTHER	PTHR12730	HSDA/SDA1-RELATED	coord: 31..686
IPR016024	Armadillo-type fold	SUPERFAMILY	SSF48371	ARM repeat	coord: 73..440

Main menu

Protein SDA1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Owlery

blazegraph-runner