Tyrosine-protein kinase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024067 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:76]) HSP 1 Score: 553.132 bits (1424), Expect = 3.674e-180 Identity = 260/465 (55.91%), Postives = 337/465 (72.47%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M CWQW+P RPSFA+++
Sbjct: 84 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVADGLITTLHYPAPKRNKPT------------------VYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIH 509
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:76]) HSP 1 Score: 552.362 bits (1422), Expect = 4.018e-180 Identity = 260/465 (55.91%), Postives = 337/465 (72.47%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M CWQW+P RPSFA+++
Sbjct: 65 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVADGLITTLHYPAPKRNKPT------------------VYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIH 490
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:77]) HSP 1 Score: 527.324 bits (1357), Expect = 5.127e-178 Identity = 258/472 (54.66%), Postives = 333/472 (70.55%), Query Frame = 3
Query: 135 SQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
+ S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR+CN+ EVT +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D+YTA GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CW+W P RPSFA+ +
Sbjct: 83 ATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKV-YVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETH 515
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:77]) HSP 1 Score: 535.798 bits (1379), Expect = 1.459e-174 Identity = 258/469 (55.01%), Postives = 332/469 (70.79%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR+CN+ EVT +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D+YTA GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CW+W P RPSFA+ +
Sbjct: 86 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKV-YVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETH 515
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:77]) HSP 1 Score: 535.028 bits (1377), Expect = 1.842e-174 Identity = 258/469 (55.01%), Postives = 332/469 (70.79%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR+CN+ EVT +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D+YTA GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CW+W P RPSFA+ +
Sbjct: 71 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKV-YVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETH 500
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: abl-1 (Tyrosine-protein kinase abl-1 [Source:UniProtKB/Swiss-Prot;Acc:P03949]) HSP 1 Score: 513.072 bits (1320), Expect = 1.208e-164 Identity = 247/493 (50.10%), Postives = 330/493 (66.94%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNR-----------GWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQ 1601
L VALYDF+ E QLS++KGD ++++ YN +W E +++ GWVP+N+IA + L Y WYHG I+R + E +L SGI GS+LVR SE+ GQ ++++R+DGRV+HYRI D +K++ IT+ KF T+ L+ HHS DGLIC L+YP KK + S S P + WE+DRSEI+MH KLGGGQYGDVYE WKR++ IAVK LKED + + +FL EA +MK+L HKNLV+LLGVC E PFY+ITE++ GNLL +LR+ ++ + P IL+ MA+QIA GM+YLE +FIHRDLAARNCLV ++ ++K+ DFGLAR++ ++D+YTA GAKFPIKWTAPEGLAFN FSSKSD+WAFGV+LWE+ATYG++PYPG+EL +VY +LE G+RMD P+GCP VY +MLQCW W P RP F ++ L + S +++ Q
Sbjct: 104 LFVALYDFHGVGEEQLSLRKGDQVRILGYNKNNEWCEARLYSTRKNDASNQRRLGEIGWVPSNFIAPY----------------NSLDKYTWYHGKISRSDSEAILGSGITGSFLVRESETSIGQYTISVRHDGRVFHYRINVDNTEKMF-ITQEVKFRTLGELVHHHSVHADGLICLLMYPASKKDKGRG-----------LFSLSPNAP-----DEWELDRSEIIMHNKLGGGQYGDVYEGYWKRHDCTIAVKALKEDA-MPLHEFLAEAAIMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFM-KEDTYTAHAGAKFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENLISSNSLNDEVQ 561
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: abl-1 (Tyrosine-protein kinase abl-1 [Source:UniProtKB/Swiss-Prot;Acc:P03949]) HSP 1 Score: 513.072 bits (1320), Expect = 1.427e-164 Identity = 247/493 (50.10%), Postives = 330/493 (66.94%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNR-----------GWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQ 1601
L VALYDF+ E QLS++KGD ++++ YN +W E +++ GWVP+N+IA + L Y WYHG I+R + E +L SGI GS+LVR SE+ GQ ++++R+DGRV+HYRI D +K++ IT+ KF T+ L+ HHS DGLIC L+YP KK + S S P + WE+DRSEI+MH KLGGGQYGDVYE WKR++ IAVK LKED + + +FL EA +MK+L HKNLV+LLGVC E PFY+ITE++ GNLL +LR+ ++ + P IL+ MA+QIA GM+YLE +FIHRDLAARNCLV ++ ++K+ DFGLAR++ ++D+YTA GAKFPIKWTAPEGLAFN FSSKSD+WAFGV+LWE+ATYG++PYPG+EL +VY +LE G+RMD P+GCP VY +MLQCW W P RP F ++ L + S +++ Q
Sbjct: 109 LFVALYDFHGVGEEQLSLRKGDQVRILGYNKNNEWCEARLYSTRKNDASNQRRLGEIGWVPSNFIAPY----------------NSLDKYTWYHGKISRSDSEAILGSGITGSFLVRESETSIGQYTISVRHDGRVFHYRINVDNTEKMF-ITQEVKFRTLGELVHHHSVHADGLICLLMYPASKKDKGRG-----------LFSLSPNAP-----DEWELDRSEIIMHNKLGGGQYGDVYEGYWKRHDCTIAVKALKEDA-MPLHEFLAEAAIMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFM-KEDTYTAHAGAKFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENLISSNSLNDEVQ 566
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: abl-1 (Tyrosine-protein kinase abl-1 [Source:UniProtKB/Swiss-Prot;Acc:P03949]) HSP 1 Score: 513.072 bits (1320), Expect = 1.792e-164 Identity = 247/493 (50.10%), Postives = 330/493 (66.94%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNR-----------GWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQ 1601
L VALYDF+ E QLS++KGD ++++ YN +W E +++ GWVP+N+IA + L Y WYHG I+R + E +L SGI GS+LVR SE+ GQ ++++R+DGRV+HYRI D +K++ IT+ KF T+ L+ HHS DGLIC L+YP KK + S S P + WE+DRSEI+MH KLGGGQYGDVYE WKR++ IAVK LKED + + +FL EA +MK+L HKNLV+LLGVC E PFY+ITE++ GNLL +LR+ ++ + P IL+ MA+QIA GM+YLE +FIHRDLAARNCLV ++ ++K+ DFGLAR++ ++D+YTA GAKFPIKWTAPEGLAFN FSSKSD+WAFGV+LWE+ATYG++PYPG+EL +VY +LE G+RMD P+GCP VY +MLQCW W P RP F ++ L + S +++ Q
Sbjct: 119 LFVALYDFHGVGEEQLSLRKGDQVRILGYNKNNEWCEARLYSTRKNDASNQRRLGEIGWVPSNFIAPY----------------NSLDKYTWYHGKISRSDSEAILGSGITGSFLVRESETSIGQYTISVRHDGRVFHYRINVDNTEKMF-ITQEVKFRTLGELVHHHSVHADGLICLLMYPASKKDKGRG-----------LFSLSPNAP-----DEWELDRSEIIMHNKLGGGQYGDVYEGYWKRHDCTIAVKALKEDA-MPLHEFLAEAAIMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFM-KEDTYTAHAGAKFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENLISSNSLNDEVQ 576
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-2 (Tyrosine protein-kinase src-2 [Source:UniProtKB/Swiss-Prot;Acc:O45539]) HSP 1 Score: 328.946 bits (842), Expect = 1.325e-102 Identity = 182/481 (37.84%), Postives = 269/481 (55.93%), Query Frame = 3
Query: 123 VDKTSQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGIN--GSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
+DK S+S VAL+ ++A + LS KK D L++++ GDW + G++P+NY+AR + + + WY G + R + E L +N G++LVR SES+ LS+++R + V HYRI +D Y+I F T+ LI H+ DGL L P K + Q F + WE+DR + + +++G GQ+G+V+E W NV +AVK LK DFL EA +MK LRH L+ L VC ++ P ++TE + + NLL FL++ + P L+ ++ Q+A GM YLEE NFIHRDLAARN L+ ++ +K+ DFGLAR + +++ Y A+ GA+FPIKWTAPE +N+F++KSD+W+FG++L E+ T+G PYPG+ +V ++ GYRM P GCP +Y IM QCW+ DP RP+F L KL
Sbjct: 50 IDKNQNISQSANFVALFQYDARTDDDLSFKKDDILEILNDTQ-GDWWFARHKATGRTGYIPSNYVAR----------------EKSIESQPWYFGKMRRIDAEKCLLHTLNEHGAFLVRDSESRQHDLSLSVRENDSVKHYRIR-QLDHGGYFIARRRPFATLHDLIAHYQREADGLCVNLGAPCAKS-------------------EAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGRWN-VNVPVAVKKLKAG-TADPTDFLAEAQIMKKLRHPKLLSLYAVCTRDEPILIVTELMQE-NLLTFLQRRGRQCQMPQ-LVEISAQVAAGMAYLEEMNFIHRDLAARNILINNSLSVKIADFGLARILMKENEYEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTEIVTFGRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPDKRPTFETLQWKL 489
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56]) HSP 1 Score: 322.398 bits (825), Expect = 1.809e-100 Identity = 181/483 (37.47%), Postives = 269/483 (55.69%), Query Frame = 3
Query: 141 SSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSG--INGSYLVRASESQPGQLSVTLR------YDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNY----LLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVY-GIMLQCWQWDPLLRPSFAQLY 1550
+ E LVALY +++ + LS +KGD + L+ +++ DW V + G+VP N++A+ + + +WY G I R E L+ S G++L+R E+ + ++T+R G V HY+I + Y+IT F ++ L++++S PDGL C L +P P+ T + + +NWEI R+++ + +KLG G +G+V+ W R V +A+KT+K + E FL+EA +MK H NLV+L VC +E PFY+ITEY+ G+LL +LR + + L+ MA QIA+GM YLEE +HRDLAARN LVGD ++KV DFGLAR + +D Y A+ GAKFPIKWTAPE F+ KSD+W++G++L+E+ T G PYPG+ +V +E GYRM P GCPE +Y ++L+CW P RP+F LY
Sbjct: 14 AQERETLVALYPYDSRADGDLSFQKGDAMYLLDHSNC-DWWYVRHQRTGQTGYVPRNFVAK----------------QQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLS------------------HDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKW-RGIVEVAIKTMKPG-TMSPEAFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLR-TDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTLY 458
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Abl (gene:FBgn0000017 transcript:FBtr0330135) HSP 1 Score: 559.296 bits (1440), Expect = 2.484e-179 Identity = 267/473 (56.45%), Postives = 336/473 (71.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDG--LICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYI 1568
L VALYDF A E+QLS+KKG+ ++++SYN G+W E S S N GWVP+NY+ L + L + WYHG I+R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D D K++ +T+ KF T+A L+ HHS +G LI LLYP PK+ + T P+ + + WEI R++I+M KLGGGQYG+VYEAVWKRY +AVKTLKED + ++DFL+EA +MK ++H NLVQL+GVC +EPPFY+ITE++S GNLL FLR + + LLYMATQIA GM+YLE N+IHRDLAARNCLVGDN L+KV DFGLAR + RDD+YTA GAKFPIKWTAPEGLA+NKFS+KSD+WAFGV+LWE+ATYG+SPYP I+L DVYH L+KGYRM+RP GCP VY +M QCWQWD RP+F ++ L ++
Sbjct: 191 LFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHS-DSGNVGWVPSNYVTPL----------------NSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVF-VTQEAKFNTLAELVHHHSVPHEGHGLITPLLYPAPKQNKPT------------------VFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKED-TMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLM-RDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHM 625
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Abl (gene:FBgn0000017 transcript:FBtr0330134) HSP 1 Score: 558.14 bits (1437), Expect = 8.565e-179 Identity = 267/473 (56.45%), Postives = 336/473 (71.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDG--LICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYI 1568
L VALYDF A E+QLS+KKG+ ++++SYN G+W E S S N GWVP+NY+ L + L + WYHG I+R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D D K++ +T+ KF T+A L+ HHS +G LI LLYP PK+ + T P+ + + WEI R++I+M KLGGGQYG+VYEAVWKRY +AVKTLKED + ++DFL+EA +MK ++H NLVQL+GVC +EPPFY+ITE++S GNLL FLR + + LLYMATQIA GM+YLE N+IHRDLAARNCLVGDN L+KV DFGLAR + RDD+YTA GAKFPIKWTAPEGLA+NKFS+KSD+WAFGV+LWE+ATYG+SPYP I+L DVYH L+KGYRM+RP GCP VY +M QCWQWD RP+F ++ L ++
Sbjct: 209 LFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHS-DSGNVGWVPSNYVTPL----------------NSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVF-VTQEAKFNTLAELVHHHSVPHEGHGLITPLLYPAPKQNKPT------------------VFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKED-TMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLM-RDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHM 643
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Abl (gene:FBgn0000017 transcript:FBtr0330132) HSP 1 Score: 558.91 bits (1439), Expect = 2.046e-178 Identity = 267/473 (56.45%), Postives = 336/473 (71.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDG--LICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYI 1568
L VALYDF A E+QLS+KKG+ ++++SYN G+W E S S N GWVP+NY+ L + L + WYHG I+R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D D K++ +T+ KF T+A L+ HHS +G LI LLYP PK+ + T P+ + + WEI R++I+M KLGGGQYG+VYEAVWKRY +AVKTLKED + ++DFL+EA +MK ++H NLVQL+GVC +EPPFY+ITE++S GNLL FLR + + LLYMATQIA GM+YLE N+IHRDLAARNCLVGDN L+KV DFGLAR + RDD+YTA GAKFPIKWTAPEGLA+NKFS+KSD+WAFGV+LWE+ATYG+SPYP I+L DVYH L+KGYRM+RP GCP VY +M QCWQWD RP+F ++ L ++
Sbjct: 191 LFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHS-DSGNVGWVPSNYVTPL----------------NSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVF-VTQEAKFNTLAELVHHHSVPHEGHGLITPLLYPAPKQNKPT------------------VFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKED-TMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLM-RDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHM 625
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Abl (gene:FBgn0000017 transcript:FBtr0345369) HSP 1 Score: 559.296 bits (1440), Expect = 2.627e-178 Identity = 267/473 (56.45%), Postives = 336/473 (71.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDG--LICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYI 1568
L VALYDF A E+QLS+KKG+ ++++SYN G+W E S S N GWVP+NY+ L + L + WYHG I+R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D D K++ +T+ KF T+A L+ HHS +G LI LLYP PK+ + T P+ + + WEI R++I+M KLGGGQYG+VYEAVWKRY +AVKTLKED + ++DFL+EA +MK ++H NLVQL+GVC +EPPFY+ITE++S GNLL FLR + + LLYMATQIA GM+YLE N+IHRDLAARNCLVGDN L+KV DFGLAR + RDD+YTA GAKFPIKWTAPEGLA+NKFS+KSD+WAFGV+LWE+ATYG+SPYP I+L DVYH L+KGYRM+RP GCP VY +M QCWQWD RP+F ++ L ++
Sbjct: 191 LFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHS-DSGNVGWVPSNYVTPL----------------NSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVF-VTQEAKFNTLAELVHHHSVPHEGHGLITPLLYPAPKQNKPT------------------VFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKED-TMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLM-RDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHM 625
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Abl (gene:FBgn0000017 transcript:FBtr0075357) HSP 1 Score: 559.296 bits (1440), Expect = 2.627e-178 Identity = 267/473 (56.45%), Postives = 336/473 (71.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDG--LICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYI 1568
L VALYDF A E+QLS+KKG+ ++++SYN G+W E S S N GWVP+NY+ L + L + WYHG I+R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D D K++ +T+ KF T+A L+ HHS +G LI LLYP PK+ + T P+ + + WEI R++I+M KLGGGQYG+VYEAVWKRY +AVKTLKED + ++DFL+EA +MK ++H NLVQL+GVC +EPPFY+ITE++S GNLL FLR + + LLYMATQIA GM+YLE N+IHRDLAARNCLVGDN L+KV DFGLAR + RDD+YTA GAKFPIKWTAPEGLA+NKFS+KSD+WAFGV+LWE+ATYG+SPYP I+L DVYH L+KGYRM+RP GCP VY +M QCWQWD RP+F ++ L ++
Sbjct: 191 LFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHS-DSGNVGWVPSNYVTPL----------------NSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVF-VTQEAKFNTLAELVHHHSVPHEGHGLITPLLYPAPKQNKPT------------------VFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKED-TMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLM-RDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHM 625
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: abl1 (c-abl oncogene 1, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-100812-9]) HSP 1 Score: 550.436 bits (1417), Expect = 4.859e-180 Identity = 260/465 (55.91%), Postives = 335/465 (72.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRMDRPEGCPE VY +M CW+W+P RPSFA+ +
Sbjct: 79 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTHGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENNLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMDRPEGCPEKVYELMRACWRWNPAERPSFAETH 504
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: abl1 (c-abl oncogene 1, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-100812-9]) HSP 1 Score: 549.28 bits (1414), Expect = 6.195e-180 Identity = 260/465 (55.91%), Postives = 335/465 (72.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRMDRPEGCPE VY +M CW+W+P RPSFA+ +
Sbjct: 60 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTHGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENNLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMDRPEGCPEKVYELMRACWRWNPAERPSFAETH 485
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: abl2 (c-abl oncogene 2, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-020809-2]) HSP 1 Score: 528.094 bits (1359), Expect = 7.200e-178 Identity = 258/472 (54.66%), Postives = 333/472 (70.55%), Query Frame = 3
Query: 135 SQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
+ S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR+C + +V +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D+YTA GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CWQW PL RPSFA+++
Sbjct: 62 AAESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTASDGKV-YVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYNLTVAVKTLKED-TMEVEEFLKEASVMKEVKHPNLVQLLGVCTLEPPFYIVTEYMPHGNLLDYLRECERDQVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWQWSPLDRPSFAEIH 494
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: abl2 (c-abl oncogene 2, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-020809-2]) HSP 1 Score: 534.258 bits (1375), Expect = 2.488e-173 Identity = 258/469 (55.01%), Postives = 332/469 (70.79%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR+C + +V +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D+YTA GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CWQW PL RPSFA+++
Sbjct: 65 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTASDGKV-YVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYNLTVAVKTLKED-TMEVEEFLKEASVMKEVKHPNLVQLLGVCTLEPPFYIVTEYMPHGNLLDYLRECERDQVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWQWSPLDRPSFAEIH 494
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: abl2 (c-abl oncogene 2, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-020809-2]) HSP 1 Score: 534.258 bits (1375), Expect = 7.647e-173 Identity = 258/469 (55.01%), Postives = 332/469 (70.79%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR+C + +V +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D+YTA GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CWQW PL RPSFA+++
Sbjct: 112 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTASDGKV-YVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYNLTVAVKTLKED-TMEVEEFLKEASVMKEVKHPNLVQLLGVCTLEPPFYIVTEYMPHGNLLDYLRECERDQVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWQWSPLDRPSFAEIH 541
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:NCBI gene;Acc:100490771]) HSP 1 Score: 555.444 bits (1430), Expect = 0.000e+0 Identity = 262/465 (56.34%), Postives = 337/465 (72.47%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI +N + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY ++ + +F T+A L+ HHST DGLI L YP PK+ + T + + + WEI+R++I M KLGGGQYG+VYE VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR CN+ EVT +LL+MATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M +CWQW PL RPSFA+++
Sbjct: 84 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPVNSPEK----------------HSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY-VSSDSRFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEIERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEVKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRDCNRQEVTAVVLLHMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRECWQWSPLDRPSFAEIH 509
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:NCBI gene;Acc:100490771]) HSP 1 Score: 555.058 bits (1429), Expect = 0.000e+0 Identity = 262/465 (56.34%), Postives = 337/465 (72.47%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI +N + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY ++ + +F T+A L+ HHST DGLI L YP PK+ + T + + + WEI+R++I M KLGGGQYG+VYE VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR CN+ EVT +LL+MATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M +CWQW PL RPSFA+++
Sbjct: 92 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPVNSPEK----------------HSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY-VSSDSRFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEIERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEVKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRDCNRQEVTAVVLLHMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRECWQWSPLDRPSFAEIH 517
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:NCBI gene;Acc:100490771]) HSP 1 Score: 555.058 bits (1429), Expect = 0.000e+0 Identity = 262/465 (56.34%), Postives = 337/465 (72.47%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI +N + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY ++ + +F T+A L+ HHST DGLI L YP PK+ + T + + + WEI+R++I M KLGGGQYG+VYE VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR CN+ EVT +LL+MATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M +CWQW PL RPSFA+++
Sbjct: 84 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPVNSPEK----------------HSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY-VSSDSRFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEIERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEVKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRDCNRQEVTAVVLLHMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRECWQWSPLDRPSFAEIH 509
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:NCBI gene;Acc:100490771]) HSP 1 Score: 554.673 bits (1428), Expect = 0.000e+0 Identity = 262/465 (56.34%), Postives = 337/465 (72.47%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI +N + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY ++ + +F T+A L+ HHST DGLI L YP PK+ + T + + + WEI+R++I M KLGGGQYG+VYE VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR CN+ EVT +LL+MATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M +CWQW PL RPSFA+++
Sbjct: 84 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPVNSPEK----------------HSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY-VSSDSRFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEIERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEVKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRDCNRQEVTAVVLLHMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRECWQWSPLDRPSFAEIH 509
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:NCBI gene;Acc:100490771]) HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0 Identity = 262/465 (56.34%), Postives = 337/465 (72.47%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI +N + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY ++ + +F T+A L+ HHST DGLI L YP PK+ + T + + + WEI+R++I M KLGGGQYG+VYE VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR CN+ EVT +LL+MATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M +CWQW PL RPSFA+++
Sbjct: 84 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPVNSPEK----------------HSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY-VSSDSRFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEIERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEVKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRDCNRQEVTAVVLLHMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRECWQWSPLDRPSFAEIH 509
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Abl1 (c-abl oncogene 1, non-receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:87859]) HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0 Identity = 260/465 (55.91%), Postives = 338/465 (72.69%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV+ +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M CWQW+P RPSFA+++
Sbjct: 84 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVADGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIH 509
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Abl1 (c-abl oncogene 1, non-receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:87859]) HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0 Identity = 260/465 (55.91%), Postives = 338/465 (72.69%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV+ +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M CWQW+P RPSFA+++
Sbjct: 65 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVADGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIH 490
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Abl2 (v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) [Source:MGI Symbol;Acc:MGI:87860]) HSP 1 Score: 533.872 bits (1374), Expect = 1.097e-173 Identity = 257/469 (54.80%), Postives = 332/469 (70.79%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR+C++ EVT +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D+YTA GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CW+W P RPSFA+ +
Sbjct: 107 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKV-YVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETH 536
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Abl2 (v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) [Source:MGI Symbol;Acc:MGI:87860]) HSP 1 Score: 534.258 bits (1375), Expect = 8.610e-173 Identity = 257/469 (54.80%), Postives = 332/469 (70.79%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR+C++ EVT +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D+YTA GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CW+W P RPSFA+ +
Sbjct: 107 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKV-YVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETH 536
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Fyn (Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602]) HSP 1 Score: 327.405 bits (838), Expect = 2.419e-101 Identity = 186/480 (38.75%), Postives = 273/480 (56.88%), Query Frame = 3
Query: 129 KTSQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGIN--GSYLVRASESQPGQLSVTLR-----YDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQL 1547
+T + L VALYD+ A E LS KG+ ++++ + GDW E S T+ G++P+NY+A + + A +WY G + R++ E L S N G++L+R SE+ G S+++R V HY+I +D YYIT +F T+ L+QH+S GL C L+ P K + + V + +DV WEI R + + ++LG GQ+G+V+ W N +A+KTLK + E FL+EA +MK L+H LVQL V + E P Y++TEY+SKG+LL FL+ + L+ MA Q+A GM Y+E N+IHRDL + N LVG+ + K+ DFGLAR I+ D+ YTA+ GAKFPIKWTAPE + +F+ KSD+W+FG++L EL T G PYPG+ +V +E+GYRM P+ CP ++ +M+ CW+ DP RP+F L
Sbjct: 77 RTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSE-GDWWEARSLTTGETGYIPSNYVAPV----------------DSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKI-RKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKT----------------KDV--WEIPRESLQLIKRLGNGQFGEVWMGTWNG-NTKVAIKTLKPG-TMSPESFLEEAQIMKKLKHDKLVQLYAV-VSEEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYL 516
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P10447|ABL_FSVHY (Tyrosine-protein kinase transforming protein Abl OS=Feline sarcoma virus (strain Hardy-Zuckerman 2) OX=11776 GN=ABL PE=2 SV=1) HSP 1 Score: 536.954 bits (1382), Expect = 0.000e+0 Identity = 257/465 (55.27%), Postives = 335/465 (72.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY ++ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA G KFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M CWQW+P RP+FA+++
Sbjct: 14 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY-VSPESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPT------------------VYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAHAGTKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAFAEIH 439
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P00520|ABL1_MOUSE (Tyrosine-protein kinase ABL1 OS=Mus musculus OX=10090 GN=Abl1 PE=1 SV=3) HSP 1 Score: 553.903 bits (1426), Expect = 5.220e-180 Identity = 260/465 (55.91%), Postives = 338/465 (72.69%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV+ +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M CWQW+P RPSFA+++
Sbjct: 65 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVADGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIH 490
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P00519|ABL1_HUMAN (Tyrosine-protein kinase ABL1 OS=Homo sapiens OX=9606 GN=ABL1 PE=1 SV=4) HSP 1 Score: 552.362 bits (1422), Expect = 1.930e-179 Identity = 260/465 (55.91%), Postives = 337/465 (72.47%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRM+RPEGCPE VY +M CWQW+P RPSFA+++
Sbjct: 65 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVADGLITTLHYPAPKRNKPT------------------VYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIH 490
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P00522|ABL_DROME (Tyrosine-protein kinase Abl OS=Drosophila melanogaster OX=7227 GN=Abl PE=1 SV=3) HSP 1 Score: 559.296 bits (1440), Expect = 2.634e-177 Identity = 267/473 (56.45%), Postives = 336/473 (71.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDG--LICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYI 1568
L VALYDF A E+QLS+KKG+ ++++SYN G+W E S S N GWVP+NY+ L + L + WYHG I+R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D D K++ +T+ KF T+A L+ HHS +G LI LLYP PK+ + T P+ + + WEI R++I+M KLGGGQYG+VYEAVWKRY +AVKTLKED + ++DFL+EA +MK ++H NLVQL+GVC +EPPFY+ITE++S GNLL FLR + + LLYMATQIA GM+YLE N+IHRDLAARNCLVGDN L+KV DFGLAR + RDD+YTA GAKFPIKWTAPEGLA+NKFS+KSD+WAFGV+LWE+ATYG+SPYP I+L DVYH L+KGYRM+RP GCP VY +M QCWQWD RP+F ++ L ++
Sbjct: 191 LFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHS-DSGNVGWVPSNYVTPL----------------NSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVF-VTQEAKFNTLAELVHHHSVPHEGHGLITPLLYPAPKQNKPT------------------VFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKED-TMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLM-RDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHM 625
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P42684|ABL2_HUMAN (Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1) HSP 1 Score: 535.798 bits (1379), Expect = 1.859e-172 Identity = 258/469 (55.01%), Postives = 332/469 (70.79%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+Y++ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR+CN+ EVT +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D+YTA GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CW+W P RPSFA+ +
Sbjct: 107 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKV-YVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETH 536
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A1S6KMF5 (Tyrosine-protein kinase OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 1619.36 bits (4192), Expect = 0.000e+0 Identity = 884/886 (99.77%), Postives = 884/886 (99.77%), Query Frame = 3
Query: 54 MGSIQTXXXXXXXXXXXXXXEDYVDKTSQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQVSNSLSMDKSQFKTSKGNINDYKNDNAKMINKQFDQNSIMMMQKSYQVCDPTSVMSPKKKALIKSKLANDSALTGSRNKVEFEESTPDXXXXXXXXXXXXXXXXXXXQQTNTYKTSNCTSFQXXXXXXXXXXXXXXXXXXXXXXHKKALIQNPDIEQFSTLPPKDRIDMYLESLDELXXXXXXXXXETDEYDDGVESNTEEIITNADNYSVASDSPPLNRHQ-NNDKLEMYCKHFKDDGSSSQVYQSPYISSSTNNKQIISKESLCDCLNDLILQTEFMFATFPKSISDLMNLSAQLKVCQTHIELLFKCKEVSNQNDLMQAYTNLKNSINSLDCCNDTDNATFINNILKFVQESLNTLKERINYIFKND 2708
MGSIQTKQSASNSSISKNNKED VDKTSQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLNPIINQNNIKNKPANDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVISKKSDFNISSSSQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQVSNSLSMDKSQFKTSKGNINDYKNDNAKMINKQFDQNSIMMMQKSYQVCDPTSVMSPKKKALIKSKLANDSALTGSRNKVEFEESTPDESGVGESVLSSESTTGSLTQQTNTYKTSNCTSFQMNNYLERNNYYLSSSSLVSMMMHKKALIQNPDIEQFSTLPPKDRIDMYLESLDELNTNNKNNVNETDEYDDGVESNTEEIITNADNYSVASDSPPLNRHQ NNDKLEMYCKHFKDDGSSSQVYQSPYISSSTNNKQIISKESLCDCLNDLILQTEFMFATFPKSISDLMNLSAQLKVCQTHIELLFKCKEVSNQNDLMQAYTNLKNSINSLDCCNDTDNATFINNILKFVQESLNTLKERINYIFKND
Sbjct: 1 MGSIQTKQSASNSSISKNNKEDNVDKTSQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLNPIINQNNIKNKPANDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVISKKSDFNISSSSQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQVSNSLSMDKSQFKTSKGNINDYKNDNAKMINKQFDQNSIMMMQKSYQVCDPTSVMSPKKKALIKSKLANDSALTGSRNKVEFEESTPDESGVGESVLSSESTTGSLTQQTNTYKTSNCTSFQMNNYLERNNYYLSSSSLVSMMMHKKALIQNPDIEQFSTLPPKDRIDMYLESLDELNTNNKNNVNETDEYDDGVESNTEEIITNADNYSVASDSPPLNRHQNNNDKLEMYCKHFKDDGSSSQVYQSPYISSSTNNKQIISKESLCDCLNDLILQTEFMFATFPKSISDLMNLSAQLKVCQTHIELLFKCKEVSNQNDLMQAYTNLKNSINSLDCCNDTDNATFINNILKFVQESLNTLKERINYIFKND 886
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: I4ENX0 (Tyrosine-protein kinase OS=Echinococcus multilocularis OX=6211 GN=abl1 PE=2 SV=1) HSP 1 Score: 582.408 bits (1500), Expect = 0.000e+0 Identity = 286/513 (55.75%), Postives = 356/513 (69.40%), Query Frame = 3
Query: 129 KTSQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSH----------------NRGWVPTNY------------IARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVR-------TTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQ-RDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
+TS E +++ LYDF+AT++SQL++K+G+ ++L+SY+ GDWSEVE+ SH RGWVPT+Y I + + + + MAY WYHG ++RQ E LLRSGI GSYLVR SES PGQLSVT+R GRVYHYRI D Y+ITE H+FPTV LI HHS DGLIC LLYP ++ + TN+ V + ++WEIDRSEI+M KLG GQYGDVYEA+WKRYN ++AVKTLK+D++L + DFL EA +MKNL+HKNLV+ LGVC +EPP+Y++ EY+ GNLL++LR+ + E+TP ILLYMA QIA GM YLE NNFIHRDLAARNCLVGD Y +KV DFGLARY+Q +D+YTA+ GAKFPIKWTAPEGLA+ +FSSKSD+WAFGVVLWELATYGLSPYPG+ELH VY +LEKGYRM RP GCPE VY IML+CW W+ RP+F + ++L
Sbjct: 55 ETSGLVEQCIMIVLYDFSATLDSQLTVKRGEIVRLLSYSPAGDWSEVEA-PSHLPNRTPRVPWAGAGGWVRGWVPTSYLTEHVRPPRVGGIGSGTNGWRRVGDEEEAGAAAATMAYPWYHGAVSRQAAEQLLRSGITGSYLVRESESAPGQLSVTVRNLGRVYHYRISRD-SCGWYFITETHRFPTVVQLIHHHSQAADGLICPLLYPAARREQPSVMRGAATNSGAVEGCADSKGGGG------YVGFDDWEIDRSEIMMRNKLGWGQYGDVYEALWKRYNSIVAVKTLKQDVDLNLNDFLAEASIMKNLQHKNLVRFLGVCTREPPYYIVAEYMPHGNLLNYLRQRSPGELTPPILLYMAVQIASGMAYLEANNFIHRDLAARNCLVGDQYTIKVADFGLARYMQLHEDTYTARNGAKFPIKWTAPEGLAYFRFSSKSDVWAFGVVLWELATYGLSPYPGVELHGVYQLLEKGYRMQRPHGCPESVYSIMLRCWSWEAADRPTFLSIKAEL 559
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A5K3EYM5 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 580.867 bits (1496), Expect = 0.000e+0 Identity = 277/487 (56.88%), Postives = 348/487 (71.46%), Query Frame = 3
Query: 147 ESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVES---------------FTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQ-RDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
E +++ LYDF AT+ESQL++K+G+ ++L+ Y+ GDWSEVE+ S RGWVPT+Y+ +AY WYHG ++R E LLRSGI GSYLVR SES PGQLSVT+R GRVYHYRI D ++ITE H+FPTV LI HHS DGLIC LLYP K+ + + + N +++WEIDRSEI+M KLG GQYGDVYEA+W+R+N ++AVKTLK+D+NL + DFL EA +MKNL+HKNLV+LLGVC +EPP+Y++TEY+ GNLL++LR+ + E+TP +LLYMA QIA GM YLE NNFIHRDLAARNCLVG+ + +KV DFGLARY++ +D+YTA+ GAKFPIKWTAPEGLA+ +FSSKSD+WAFGVVLWELATYGLSPYPG+ELH VY +LEKGYRM RP GCPE VY IML+CW W+ RPSFA++ ++L
Sbjct: 61 EQCIMIVLYDFTATLESQLTVKRGELVRLLGYSPAGDWSEVEAPYRLPNRTPRVAWGGVGSWVRGWVPTSYLTE----HVAPCGGGVGDYQRDEVAYPWYHGAVSRHAAEQLLRSGITGSYLVRESESAPGQLSVTVRNLGRVYHYRISRD-SSGWFFITETHRFPTVVQLIHHHSQAADGLICPLLYPAAKREQPALRGTIQASSGLDNCGV--------GLDDWEIDRSEIMMRNKLGWGQYGDVYEALWRRHNSIVAVKTLKQDVNLNLNDFLAEASIMKNLQHKNLVRLLGVCTREPPYYIVTEYMPHGNLLNYLRQRSPGELTPPVLLYMAVQIASGMAYLEANNFIHRDLAARNCLVGEQHTIKVADFGLARYMRLHEDTYTARNGAKFPIKWTAPEGLAYFRFSSKSDVWAFGVVLWELATYGLSPYPGVELHGVYQLLEKGYRMQRPHGCPEPVYNIMLRCWSWEAADRPSFAEVRAEL 534
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A5K3EWG1 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0 Identity = 277/487 (56.88%), Postives = 348/487 (71.46%), Query Frame = 3
Query: 147 ESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVES---------------FTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQ-RDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
E +++ LYDF AT+ESQL++K+G+ ++L+ Y+ GDWSEVE+ S RGWVPT+Y+ +AY WYHG ++R E LLRSGI GSYLVR SES PGQLSVT+R GRVYHYRI D ++ITE H+FPTV LI HHS DGLIC LLYP K+ + + + N +++WEIDRSEI+M KLG GQYGDVYEA+W+R+N ++AVKTLK+D+NL + DFL EA +MKNL+HKNLV+LLGVC +EPP+Y++TEY+ GNLL++LR+ + E+TP +LLYMA QIA GM YLE NNFIHRDLAARNCLVG+ + +KV DFGLARY++ +D+YTA+ GAKFPIKWTAPEGLA+ +FSSKSD+WAFGVVLWELATYGLSPYPG+ELH VY +LEKGYRM RP GCPE VY IML+CW W+ RPSFA++ ++L
Sbjct: 37 EQCIMIVLYDFTATLESQLTVKRGELVRLLGYSPAGDWSEVEAPYRLPNRTPRVAWGGVGSWVRGWVPTSYLTE----HVAPCGGGVGDYQRDEVAYPWYHGAVSRHAAEQLLRSGITGSYLVRESESAPGQLSVTVRNLGRVYHYRISRD-SSGWFFITETHRFPTVVQLIHHHSQAADGLICPLLYPAAKREQPALRGTIQASSGLDNCGV--------GLDDWEIDRSEIMMRNKLGWGQYGDVYEALWRRHNSIVAVKTLKQDVNLNLNDFLAEASIMKNLQHKNLVRLLGVCTREPPYYIVTEYMPHGNLLNYLRQRSPGELTPPVLLYMAVQIASGMAYLEANNFIHRDLAARNCLVGEQHTIKVADFGLARYMRLHEDTYTARNGAKFPIKWTAPEGLAYFRFSSKSDVWAFGVVLWELATYGLSPYPGVELHGVYQLLEKGYRMQRPHGCPEPVYNIMLRCWSWEAADRPSFAEVRAEL 510
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A0C9PHZ8 (Abl_0 protein OS=Fopius arisanus OX=64838 GN=Abl_3 PE=3 SV=1) HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0 Identity = 278/509 (54.62%), Postives = 359/509 (70.53%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYI----CFSQNVDWSYQVSN---SLSMDKSQFKTSKGNIN 1661
L VALYDF A E+QLS+KKG+ ++++SYN G+W E S T GWVP+NY+ + + L + WYHG I R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D D K++ TE+ KF T+A L+ HHS DGLI LLYP PK + T P+ + + WEI+R++I+M KLGGGQYGDVYEAVWKRYN+ +AVKTLKED + ++DFL+EA +MK ++H+NLVQLLGVC +EPPFY+ITE++SKGNLL +LR ++ ++ +L++MATQIA GM+YLE NFIHRDLAARNCLVG+N+L+KV DFGLAR + RDD+YTA GAKFPIKWTAPEGLA+NKFS+KSD+WAFG++LWE+ATYG+SPYPG++L DVYH+LEKGYRM+ P GCP VY +M QCWQW + RP+F +++ L + S+ V+ Q +LS KSQ S GNI+
Sbjct: 111 LFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHSSTGQ-VGWVPSNYVTPV----------------NSLEKHSWYHGRIARNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDSDGKMFVTTES-KFNTLAELVHHHSMLADGLITQLLYPAPKHNKPT------------------VFPLSPEPDEWEINRTDIVMRHKLGGGQYGDVYEAVWKRYNMTVAVKTLKED-TMALKDFLEEAAIMKEMKHRNLVQLLGVCTREPPFYIITEFMSKGNLLDYLRNESKHQINAVVLMHMATQIASGMSYLESRNFIHRDLAARNCLVGENHLVKVADFGLARLM-RDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGILLWEIATYGMSPYPGVDLTDVYHMLEKGYRMECPPGCPPKVYELMRQCWQWSAVERPTFKEIHHSLENMFQDSSISEEVEKQLQGGGDTPTLSYKKSQ-TGSTGNIH 580
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: abl1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:NCBI gene;Acc:103046185]) HSP 1 Score: 555.058 bits (1429), Expect = 0.000e+0 Identity = 261/465 (56.13%), Postives = 336/465 (72.26%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRMDRPEGCPE VY +M CW+W+P RPSFA+ +
Sbjct: 81 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVADGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTHGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMDRPEGCPEKVYELMRACWKWNPAERPSFAETH 506
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: abl1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:NCBI gene;Acc:103046185]) HSP 1 Score: 554.673 bits (1428), Expect = 0.000e+0 Identity = 261/465 (56.13%), Postives = 336/465 (72.26%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEK YRMDRPEGCPE VY +M CW+W+P RPSFA+ +
Sbjct: 64 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVADGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTHGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMDRPEGCPEKVYELMRACWKWNPAERPSFAETH 489
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: abl2 (ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:NCBI gene;Acc:103022317]) HSP 1 Score: 528.48 bits (1360), Expect = 2.722e-171 Identity = 275/563 (48.85%), Postives = 362/563 (64.30%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQVSNSLSMDKSQFKTSKGNINDYKNDNAKMINKQFDQNSIMMMQKSYQVCD-PTSVMSPKKKALIKSKLANDSALTGS 1829
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR C + EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D Y A GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CWQW PL RPSFA+ + + ++ S +V+ L S K G ++ + +D + K Q +++ + + P + L S LA D +GS
Sbjct: 35 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTASDGKV-YVTSESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEVKHPNLVQLLGVCTLEPPFYIVTEYMLHGNLLDYLRDCEREEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDIYKAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWQWSPLDRPSFAETHQAFETMFHDSSI--SEEVAEELCKTASSGKG--GVVHAFGHDQPLLPCKARPQKKHSDNKENMEGLEGPQEPGAHGPAGLAASLLAGDCRSSGS 554
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: abl2 (ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:NCBI gene;Acc:103022317]) HSP 1 Score: 528.094 bits (1359), Expect = 3.844e-171 Identity = 275/563 (48.85%), Postives = 362/563 (64.30%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQVSNSLSMDKSQFKTSKGNINDYKNDNAKMINKQFDQNSIMMMQKSYQVCD-PTSVMSPKKKALIKSKLANDSALTGS 1829
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR C + EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D Y A GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CWQW PL RPSFA+ + + ++ S +V+ L S K G ++ + +D + K Q +++ + + P + L S LA D +GS
Sbjct: 45 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTASDGKV-YVTSESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEVKHPNLVQLLGVCTLEPPFYIVTEYMLHGNLLDYLRDCEREEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDIYKAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWQWSPLDRPSFAETHQAFETMFHDSSI--SEEVAEELCKTASSGK--GGVVHAFGHDQPLLPCKARPQKKHSDNKENMEGLEGPQEPGAHGPAGLAASLLAGDCRSSGS 564
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: abl2 (ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:NCBI gene;Acc:103022317]) HSP 1 Score: 528.094 bits (1359), Expect = 7.867e-171 Identity = 275/563 (48.85%), Postives = 362/563 (64.30%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQVSNSLSMDKSQFKTSKGNINDYKNDNAKMINKQFDQNSIMMMQKSYQVCD-PTSVMSPKKKALIKSKLANDSALTGS 1829
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+ Y+T +F T+A L+ HHST DGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR C + EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D Y A GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM++PEGCP VY +M CWQW PL RPSFA+ + + ++ S +V+ L S K G ++ + +D + K Q +++ + + P + L S LA D +GS
Sbjct: 68 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTASDGKV-YVTSESRFSTLAELVHHHSTVADGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEVKHPNLVQLLGVCTLEPPFYIVTEYMLHGNLLDYLRDCEREEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDIYKAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWQWSPLDRPSFAETHQAFETMFHDSSI--SEEVAEELCKTASSGKG--GVVHAFGHDQPLLPCKARPQKKHSDNKENMEGLEGPQEPGAHGPAGLAASLLAGDCRSSGS 587
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: abl1 (c-abl oncogene 1, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-100812-9]) HSP 1 Score: 511.531 bits (1316), Expect = 4.998e-166 Identity = 249/507 (49.11%), Postives = 340/507 (67.06%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTL--KEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYI----CFSQNVDWSYQVSNSLSMDKSQFKTSKGNI 1658
L VALYDF A+ ++ LSI KG+ L+++ YN G+W EV S + +GWVP+NYI + + L + WYHG I+R E+LL SGINGS+L+R SES PGQLS++LR +GRVYHYRI D K Y+++ +F T+A L+ HHS+ DGLI L YP PK+ + T P ++ WEI+R++I M KLGGGQYG+VYE + K+Y+ +AVKTL +ED +++E+FLKEA +MK ++H NLVQLLGVC +EPPFY++TE+++ GNLL +LR+CN+ EVT +LL+MATQI+ M YLE+ NFIHRDLAARNCLV +++++KV DFGL+R + D+YTA+ GAKFPIKWTAPE LA+NKF + AFGV+LWE+ATYG+SPYPG++L VY LE+GYRM++PEGCP VY +M CWQW+ RPSFA+++ + S+ V+ + S M + KG+I
Sbjct: 40 LFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWCEVHS--RNGQGWVPSNYITPV----------------NSLEKHSWYHGPISRNAAEYLLSSGINGSFLLRESESSPGQLSISLRCEGRVYHYRINTASDGK-YFVSSESRFSTLAELVHHHSSVADGLIVPLHYPAPKRTKPT---------------VYGVSPTYD---RWEIERTDITMKHKLGGGQYGEVYEGLKKKYSRTVAVKTLNPRED-TMEVEEFLKEAAMMKEIKHPNLVQLLGVCTREPPFYIVTEFMTHGNLLDYLRECNRDEVTAVVLLHMATQISSAMEYLEKKNFIHRDLAARNCLVAESHMVKVADFGLSRLMT-GDTYTARAGAKFPIKWTAPESLAYNKFCAPVSCSAFGVLLWEIATYGMSPYPGVDLSQVYERLERGYRMEQPEGCPPRVYQLMQACWQWNAADRPSFAEIHQTFETMFHDSSISEEVEKELGRNGSSCMQAPKLPAKKGSI 507
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: clul1 (clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GENE-031118-57]) HSP 1 Score: 328.946 bits (842), Expect = 1.348e-103 Identity = 194/492 (39.43%), Postives = 279/492 (56.71%), Query Frame = 3
Query: 129 KTSQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHI--------GDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGIN--GSYLVRASESQPGQLSVTLR-----YDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
+T + L VALYD++A + LS +KG+ ++I+ N I GDW E S ++ N+G++P+NY+A DS + A +WY G ++R++ E L N G++L+R SE+ G S+++R V HY+I +D YYIT +F T+ L+QH+S DGL L P NEK ++ + WE+ R + + KLG G +G+V+ W +A+KTLK + E FL+EA +MK LRH LVQL V + E P Y++TE++SKG+LL FL++ + + L+ MA QIA GM Y+E N+IHRDL A N LVGDN + K+ DFGLAR I+ D+ YTA+ GAKFPIKWTAPE F +F+ KSD+W+FG++L EL T G PYPG+ +V +E+GYRM P CPE ++ +M+QCW+ DP RP+F L + L
Sbjct: 8 RTHLTGGVTLFVALYDYDARTQDDLSFRKGEKFQIIN-NTIEVAVVYREGDWWEARSLSTGNKGYIPSNYVA---------------PADS-VQAEEWYFGKVSRKDAERQLLCPGNPRGTFLIRESETTKGAYSLSIRDWDEVKGDNVKHYKIR-KLDNGGYYITTRAQFDTLQKLVQHYSEHADGLCYKLTLVCP-------NEKPQTQGLAR--------------DAWEMPRDSLKLELKLGQGCFGEVWAGTWNG-TTKVAIKTLKPG-TMSPEAFLEEAQIMKKLRHDKLVQLYAV-VSEEPIYIVTEFMSKGSLLDFLKEGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLICKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAAMFGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPPSCPESLHELMMQCWKKDPEERPTFEYLQAFL 456
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: frk (fyn-related Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-110411-7]) HSP 1 Score: 321.242 bits (822), Expect = 7.421e-101 Identity = 184/485 (37.94%), Postives = 269/485 (55.46%), Query Frame = 3
Query: 162 VALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTS-------HNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGIN--GSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYP-----VPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYI--QRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYI 1568
VALYD++ LS K+G+ L++ + DW + T+ + RG++P NY+A L A W+ G+I R + E L + +N G++L+R SES+ S+++R V HYRI + ++I+ F + L+Q++ + DGL AL P P + + N V+ WEI R+ I + ++LG G +G+V++ +W + ++AVKTLK +K E+F+ EA +MK LRH NL+QL VC +E P Y+ITE + G+LL +LR ++ L+ MA QIA GM YLE N+IHRDLAARN LVG+ + KV DFGLAR I + +D Y K GAK PIKWTAPE + F++FS KSD+W+FG++L+EL TYG PYP + +V L++GYRM +P+ CP + Y IML+CW RP+F L +L Y
Sbjct: 2 VALYDYDGRTNEDLSFKEGELLEVTDKTN-SDWWYAQKKTASTSNERYNTRGYIPANYVAEY----------------QSLDAEPWFFGDIKRADAEKYLLADVNTTGAFLIRQSESRKTDYSLSVRDGSTVKHYRIRQLDENGGFFISRRVTFQNLIELVQYYKSNSDGLCMALQKPCVVIEAPTTIGLSYN----------------------TVDKWEIPRASIQLQKRLGAGMFGEVWQGLWNN-STLVAVKTLKPGA-MKKEEFIGEAQIMKQLRHANLIQLYAVCSQEEPIYIITELMRHGSLLDYLRGPLGKQLKAPELVDMARQIAAGMAYLESQNYIHRDLAARNILVGEGKVCKVADFGLARIIKVRYEDEYEGKAGAKVPIKWTAPEAVNFHRFSVKSDVWSFGILLYELITYGRMPYPEMGNMEVLKQLDRGYRMPQPDNCPPLFYSIMLECWNKKEEERPTFETLQWRLDYF 445
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72]) HSP 1 Score: 310.457 bits (794), Expect = 7.399e-97 Identity = 179/475 (37.68%), Postives = 265/475 (55.79%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGIN--GSYLVRASESQPGQLSVTLR-YD----GRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
L+VALYDF + KKGD +++I G+W E ++G++P+NY+A+ + L +W+ ++R+EGE LL + N G+YL+R SES G S+++R YD V HY+I +D Y+I+ FP + LIQH++ DGL LL P K EK + WEI R + + ++LG GQ+G+V+ ++ +A+KT+K ++ E FL EA +MK L+H LV+L V +EP Y++TE++ G+LL +L+ + ++ MA QIA+GM ++E N+IHRDL A N LV + K+ DFGLAR I+ D+ YTA+ GAKFPIKWTAPE + + FS KSD+W+FG++L E+ T+G PYPG+ DV LE+GYRM PE P+ +YG+M+ CW+ P RP+F L L
Sbjct: 2 LVVALYDFEQLNPDDMGFKKGDKMRII--QERGEWWMAELMDGSHKGYIPSNYVAKA----------------NSLETEEWFFSGVSRKEGERLLLAPGNSIGAYLLRDSESNKGSYSLSVRDYDITNGDVVRHYKIR-TLDNGGYFISARLTFPDLFALIQHYTAHSDGLCQKLLRPCVSKKPQQLWEK----------------------DAWEIPRDSLKLSKRLGAGQFGEVWMGIYNN-RTKVAIKTMKPG-SMSPEAFLDEANLMKTLQHPRLVRLYAVVTQEP-IYIVTEFMENGSLLDYLKSTEGSTLPMPKMIDMAAQIAEGMAFIERKNYIHRDLRAANILVNEQLASKIADFGLARIIE-DNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEIITFGRIPYPGMSNSDVIRQLERGYRMPCPEQAPKQLYGVMMDCWKERPEERPTFEYLQGVL 431
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006670.1 (pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene:ENSPMAG00000006016.1 transcript:ENSPMAT00000006670.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 297.36 bits (760), Expect = 7.721e-93 Identity = 160/390 (41.03%), Postives = 236/390 (60.51%), Query Frame = 3
Query: 414 TRQEGEHLLRSG-INGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDV-----ENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQ--RDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
T Q+ L++SG ++GS+LVR SE+ S+++R V HY+I ++K ++IT ++F T+ L+Q +S +GL L P KK ++P E + + WEI RS + + ++LG GQ+G+V++ +W + +A+KTLK+ + +DFL+EA +MK LRH L+QL VC +E P Y+ITE +S G+L ++L+ + L+ MA Q+A GM YLE N+IHRDLAARN LV ++ KV DFGLAR I+ +D Y A++G+KFPIKWTAPE +N+FS KSD+W+FGV+L E+ TYG PYPG +V +++GYRM P GCP+ Y +ML+CW D RP+F L +L
Sbjct: 3 TDQQLLQLMKSGNVHGSFLVRQSETSGHGYSLSVRDGDTVKHYKIRV-LEKGSFFITRRNQFATLRDLVQSYSRDANGLCVTLNQPCLKK----------------------EMPQTEGLSSDMADKWEIPRSSVQLVKRLGAGQFGEVWQGLWNK-TTPVAIKTLKQG-TMDRDDFLREAQLMKRLRHPKLIQLYAVCTQEEPIYIITELMSNGSLANYLQTPEGRSLDLVELVDMAAQVAAGMAYLEAQNYIHRDLAARNILVAEHNACKVADFGLARVIKMSNEDEYEARVGSKFPIKWTAPEAANYNRFSIKSDVWSFGVLLHEIITYGKLPYPGQTNAEVLAAVDRGYRMPCPPGCPQAFYDLMLECWNVDDQARPTFETLQWQL 367
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]) HSP 1 Score: 103.219 bits (256), Expect = 6.648e-23 Identity = 72/261 (27.59%), Postives = 128/261 (49.04%), Query Frame = 3
Query: 804 MHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNV 1586
+ Q +G G YG VY+A+ K + V+A+K + + + ++ D + E ++KNL H N+V+ G K Y++ EY + G+L + + + Y+ TQ G+ YL IHRD+ A N L+ + +K+ DFG++ + ++ + + W APE L S+ SDIW+ G + E+ T PY + ++Y+ +E P E + + +C+ + RP+ QL K +I ++NV
Sbjct: 27 LKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYV-TQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVN-----SSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKN-PPYHNLTDANIYYAVENDTYYP-PSSFSEPLKDFLSKCFVKNMYKRPTADQLL-KHVWINSTENV 278
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]) HSP 1 Score: 94.7449 bits (234), Expect = 3.540e-20 Identity = 68/263 (25.86%), Postives = 127/263 (48.29%), Query Frame = 3
Query: 816 LGGGQYGDVYEAVWKRYNVVIAVKTLK--------EDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNK-FSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQ--------CWQWDPLLRPSFAQLYS 1553
+G G +G VY + ++AVK ++ E + +E E +K+L H N+VQ LG K + L EY++ G++ +R + + ++ ++ TQ+ G+ YL +HRD+ A N L+ + + K+ DFG++R +D + + + + W APE + + +S+K DIW+ G ++ E+ G P+ +E+ V + + G P PE ++ Q C++ +P RP+ +L S
Sbjct: 1181 IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDE--PLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRK-SKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFA-GKRPWSNLEV--VAAMFKIGKSKSAPP-IPEDTLPLISQIGRNFLDACFEINPEKRPTANELLS 1436
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]) HSP 1 Score: 91.2781 bits (225), Expect = 3.397e-19 Identity = 67/253 (26.48%), Postives = 114/253 (45.06%), Query Frame = 3
Query: 813 KLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQR-DDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPG-IELHDVYHILEKGY-RMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLY 1562
K+G G G VY A NV +A+K + + K E + E LVMK +H N+V + + + ++I EY+ G+L + C +T + + + G+ +L +HRD+ + N L+ +K+ DFG I + T +G + W APE ++ ++ K DIW+ G+++ E+ G PY L +Y I G ++ PE + + C +P R S +L Y
Sbjct: 625 KIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHC---ILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPY---WMAPEVVSRKEYGPKVDIWSLGIMIIEM-IEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEY 870
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: SPS1 (Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]) HSP 1 Score: 88.5817 bits (218), Expect = 9.243e-19 Identity = 51/197 (25.89%), Postives = 101/197 (51.27%), Query Frame = 3
Query: 816 LGGGQYGDVYEAVWKRYNVVIAVKTLK-EDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLA--FNKFSSKSDIWAFGVVLWELATYGLSP 1397
+G G +GDVY+AV + ++A+K + E + IE +E + L+ + + +++ +++ EY G+ L++ + + ++ ++ G+ YL E IHRD+ A N L+ + ++K+GDFG++ +I+ +G + W APE + + ++ K+DIW+ G+ +EL GL P
Sbjct: 24 IGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPY---WMAPEVVCCEVDGYNEKADIWSLGITTYELLK-GLPP 216
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]) HSP 1 Score: 85.5001 bits (210), Expect = 1.792e-18 Identity = 63/207 (30.43%), Postives = 108/207 (52.17%), Query Frame = 3
Query: 810 QKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIED-FLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTP-----SILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRD-DSYTAKIGAKFPIKWTAPEGLAFNK-FSSKSDIWAFGVVLWELATYGLSPYPG 1406
+KLG G Y VY+ + K V +A+K +K D ++E +MK L+H+N+V+L V E L+ E++ N L + TP +++ Y Q+ G+ + EN +HRDL +N L+ LK+GDFGLAR +++++++ + + AP+ L ++ +S+ DIW+ G +L E+ T G +PG
Sbjct: 11 EKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMD--NDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEV---VTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMIT-GKPLFPG 211
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO47195 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN18]) HSP 1 Score: 360.147 bits (923), Expect = 9.071e-118 Identity = 168/273 (61.54%), Postives = 209/273 (76.56%), Query Frame = 3
Query: 771 ENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVD 1589
+ WEI+R+EI M KLGGGQYG+VYE WK+YN +AVKTL+E+ +++E+FLKEA VMK ++H+NLVQLLGVC +EPPFY+ITE++ GNLL +LR ++ L+YMATQ+ M+YLE NFIHRDLAARNCLVGDN L+KV DFGL+R + +D YTA GAKFPIKWTAPE LA N FS KSD+WAFG++LWELATYG+SPYPGI+L VY L+ GYRM PEGCP VY +M CW WDP RPSF +++ KL + S NV+
Sbjct: 5 DEWEIERTEIAMKHKLGGGQYGEVYEGTWKKYNKTVAVKTLREE-TMEVEEFLKEASVMKGIKHQNLVQLLGVCTREPPFYIITEFMMNGNLLDYLRSPKGKDLDAVTLMYMATQVGSAMSYLESMNFIHRDLAARNCLVGDNNLVKVADFGLSRLVS-EDIYTAHQGAKFPIKWTAPEALAHNTFSIKSDVWAFGILLWELATYGMSPYPGIDLSQVYDKLDGGYRMPCPEGCPPEVYSLMQTCWCWDPNSRPSFKEIHEKLNTMFPSSNVN 275
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO49804 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFY7]) HSP 1 Score: 229.95 bits (585), Expect = 1.128e-69 Identity = 111/217 (51.15%), Postives = 147/217 (67.74%), Query Frame = 3
Query: 861 RYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQ 1511
R + +AVK +K D + EDF++EA VMK +H NLVQL G+C E P Y+I E + G LLH+LRK +Q ++ + + M Q+A M YLE +NFIHRDLAARNCL+G+N +KV DFGLARY+ DD YTA G KFPIKW APE + ++KFSSKSD+WAFG++ WE+ T G PYP DV ++ GYR+++P CP+ Y M +CW
Sbjct: 3 RGTIPVAVKMMK-DGAMSEEDFIEEAKVMKQFQHGNLVQLYGIC-SEKPIYIIQELMKGGCLLHYLRK-SQFKLQSAEMTEMVRQVAAAMKYLESHNFIHRDLAARNCLIGENRTVKVADFGLARYVI-DDEYTASEGTKFPIKWAAPEVILYSKFSSKSDVWAFGILAWEVYTGGKQPYPATNNTDVVQMVINGYRLEKPLRCPDAAYSTMRKCWH 215
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO43236 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ71]) HSP 1 Score: 227.639 bits (579), Expect = 3.641e-64 Identity = 120/293 (40.96%), Postives = 172/293 (58.70%), Query Frame = 3
Query: 747 QLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEA-----VWKRYNVVIAVKTLKEDLNL-KIEDFLKEALVMKNL-RHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKC-----------NQLEVTPSIL----LYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
+LP+ ED WEIDRS+I + ++LG G +G V +A Y +AVK LK D ++ D L E MKN+ HKN++ L+G C + P Y++ E+ GNL FLR+ + PS++ + A QIA GM YL IHRDLAARN LVG++Y++K+ DFGLAR ++ D Y + PIKW A E L ++++SD+W FG++LWE+ T G SPYPGI + ++ +L+ GYRM P+ CP+ +Y IML CW +P RPSF +L ++
Sbjct: 320 ELPIDED---WEIDRSQITIKEQLGEGAFGLVMKAEALGLTDMPYRHTVAVKMLKADATENELADLLSEMDTMKNIGSHKNIINLIGACTQNGPLYVVVEFAPHGNLRQFLRERRPSDYHRSRSDSSTHSQPSLIVRDFISFAFQIARGMEYLSFKKCIHRDLAARNILVGEDYVMKIADFGLARNVRDMDYYRKATDGRLPIKWLAIEALFDRVYTTQSDVWTFGILLWEIFTLGGSPYPGIPVEKLFELLKSGYRMQMPQKCPDKMYDIMLSCWNENPNARPSFTELRAEF 609
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO49191 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHA4]) HSP 1 Score: 225.713 bits (574), Expect = 1.505e-63 Identity = 117/291 (40.21%), Postives = 176/291 (60.48%), Query Frame = 3
Query: 747 QLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVW-----KRYNVVIAVKTLKEDLNL-KIEDFLKEALVMKNL-RHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRK-------CNQLEVTPSI------LLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
+LP+ E+ WE+DRS+I + LG G +G V +A Y +AVK LKED ++ D + E VMK + +H N++ L+G C ++ P +++ EY S+GNL FLR N L P L+ + Q+A GM YLE IHRDLAARN LV DN+++K+ DFGLAR I D Y + P+KW A E L ++++SD+WA+G+++WE+ T+G SPYPGI L ++ +L++GYRM++P C + VY +ML+CW +P RP+FA++ ++
Sbjct: 309 ELPLDEE---WELDRSQISLLGILGEGAFGRVVKADAIGLPNMPYRCNVAVKMLKEDATEHELADLVSEMEVMKTIGQHVNIINLIGACTQKGPLFVVVEYASQGNLRQFLRARRPIPEYANPLTEPPREKLKLVDLVSFSYQVARGMEYLESKKCIHRDLAARNVLVSDNHVIKIADFGLARDIHDIDYYRKTTDGRLPVKWMALEALFDRVYTAQSDVWAYGILMWEIVTFGGSPYPGIPLWKLFELLKEGYRMEQPVNCQDDVYALMLRCWHENPNQRPTFAEIVKEM 596
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO43234 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ69]) HSP 1 Score: 216.083 bits (549), Expect = 1.711e-63 Identity = 114/286 (39.86%), Postives = 164/286 (57.34%), Query Frame = 3
Query: 771 ENWEIDRSEILMHQKLGGGQYGDVYEAVW-----KRYNVVIAVKTLKEDLNLK-IEDFLKEALVMKNL-RHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRK----------CNQLEVTPSI------LLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
E WEI R I++ +K+G G +G V + + K + +AVKT+KED +++ DF+ E MK++ H N++ ++GVC + P LI E+ GNL FLRK N L +TP LL MA Q A GM YL IHRDLAARN L+ D+Y+LK+ DFGL+R ++ D Y + P+ W + E L K++ SD+W+FGV+LWE+ T G PYPGI + ++ +L+ GYRM P CP +Y +MLQCW +P RP+ + +L
Sbjct: 7 EEWEIARENIVLREKIGEGAFGLVVKGIVYGLPDKPSSCTVAVKTIKEDASIEEFNDFVSEIETMKSIGNHTNIINMVGVCSVDGPLLLIVEHAMHGNLRDFLRKHRGTHKDASQNNNLYMTPGNSLIIKNLLPMAYQAAKGMQYLASKKCIHRDLAARNVLLADDYVLKIADFGLSRNLRETDYYRKTTHGRLPVMWLSIEALFDQKYTLMSDVWSFGVLLWEIYTLGCMPYPGIPVERLFELLKTGYRMSAPTECPPEIYTLMLQCWSENPADRPTMELVAKEL 292
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: abl1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:NCBI gene;Acc:101155287]) HSP 1 Score: 550.436 bits (1417), Expect = 6.030e-180 Identity = 260/465 (55.91%), Postives = 335/465 (72.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY LEK YRM+RPEGCPE VY +M CW+W+P RPSFA+ +
Sbjct: 92 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTHGNLLDYLRECNREEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLTQVYERLEKDYRMERPEGCPEKVYELMKACWRWNPAERPSFAETH 517
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: abl1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:NCBI gene;Acc:101155287]) HSP 1 Score: 550.051 bits (1416), Expect = 6.590e-180 Identity = 260/465 (55.91%), Postives = 335/465 (72.04%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY LEK YRM+RPEGCPE VY +M CW+W+P RPSFA+ +
Sbjct: 75 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTHGNLLDYLRECNREEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLTQVYERLEKDYRMERPEGCPEKVYELMKACWRWNPAERPSFAETH 500
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: abl2 (ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:NCBI gene;Acc:101167766]) HSP 1 Score: 541.576 bits (1394), Expect = 1.242e-175 Identity = 268/519 (51.64%), Postives = 356/519 (68.59%), Query Frame = 3
Query: 144 SESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQVSNSLSMDKSQFKTSKGN-INDYKNDNAKMINK 1697
S+ L VALYDF A+ ++ LSI KG+ L+++ YN G+WSEV S + +GWVP+NYI + + L + WYHG ++R E+LL S INGS+LVR SES PGQLS++LRY+GRVYHYRI D K+Y +E+ +F T+A L+ HHST PDGL+ L YP PK N V P+ + WE++R++I M KLGGGQYG+VY VWK+YN+ +AVKTLKED +++E+FLKEA VMK ++H NLVQLLGVC EPPFY++TEY+ GNLL +LR C++ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+++KV DFGL+R + D+YTA GAKFPIKWTAPE LA+N FS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY +LEKGYRM +PEGCP VY +M CWQW+PL RPSFA+++ + ++ S +V+ L K++ + S G ++ + +D + +K
Sbjct: 95 SDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS--KNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTATDGKVYVTSES-RFATLAELVHHHSTVPDGLVTTLHYPAPK----CNKPTVYGVS-----------PIH---DKWEMERTDITMKHKLGGGQYGEVYVGVWKKYNLTVAVKTLKED-TMEVEEFLKEAAVMKEVKHPNLVQLLGVCTLEPPFYIVTEYMPHGNLLDYLRDCDKAEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMGQPEGCPPKVYELMRACWQWNPLERPSFAEIHQAFETMFHDSSI--SEEVAEELC--KTESRQSHGAPVHSFGHDTPLLPSK 570
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: abl1 (ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:NCBI gene;Acc:101155287]) HSP 1 Score: 508.834 bits (1309), Expect = 3.136e-164 Identity = 245/465 (52.69%), Postives = 321/465 (69.03%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLY 1550
L VALYDF A+ ++ LSI KG+ L+++ YNH G+W E + T + +GWVP+NYI + + L + WYHG ++R E+LL SGINGS+LVR SES PGQ S++LRY+GRVYHYRI D KLY +E+ +F T+A L+ HHST DGLI L YP PK+ + T + + + WE++R++I M KLGGGQYG+VYE VWK+YN+ +AVKTLK + M+++++ L +LGVC +EPPFY+ITE+++ GNLL +LR+CN+ EV +LLYMATQI+ M YLE+ NFIHRDLAARNCLVG+N+L+KV DFGL+R + D+YTA GAKFPIKWTAPE LA+NKFS KSD+WAFGV+LWE+ATYG+SPYPGI+L VY LEK YRM+RPEGCPE VY +M CW+W+P RPSFA+ +
Sbjct: 75 LFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ--TKNGQGWVPSNYITPV----------------NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSES-RFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPT------------------IYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKVHRH------------MEDVKNPYLFLVLGVCTREPPFYIITEFMTHGNLLDYLRECNREEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLTQVYERLEKDYRMERPEGCPEKVYELMKACWRWNPAERPSFAETH 489
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: fyna (tyrosine-protein kinase fyna [Source:NCBI gene;Acc:101157019]) HSP 1 Score: 332.798 bits (852), Expect = 1.560e-103 Identity = 190/475 (40.00%), Postives = 272/475 (57.26%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGE-HLLRSG-INGSYLVRASESQPGQLSVTLR-----YDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
L VALYD+ A E LS +KG+ ++++ GDW E S T+ G++P+NY+A + + A WY G + R++ E LL SG G++L+R SE+ G S++++ V HY+I +D YYIT +F T+ L+QH+S GL C L+ P K + + V + +DV WEI R + + ++LG GQ+G+V+ W +AVKTLK + E FL+EA +MK LRH LVQL V + E P Y++TEY+SKG+LL FL+ + L+ MA Q+A GM Y+E N+IHRDL + N LVGD + K+ DFGLAR I+ D+ YTA+ GAKFPIKWTAPE + KF+ KSD+W+FG++L EL T G PYPG+ +V +E+GYRM P+ CP ++ +M+QCW+ DP RP+F L + L
Sbjct: 86 LFVALYDYEARTEDDLSFRKGERFQILNSTE-GDWWEARSLTTGGTGYIPSNYVAPV----------------DSIQAEDWYFGKLGRKDAERQLLSSGNARGTFLIRESETTKGAYSLSIQDWDDIKGDHVKHYKI-RKLDNGGYYITTRAQFETLQQLVQHYSARAAGLCCRLIAPCHKGMPRLTDLSVKT----------------KDV--WEIPRESLQLIKRLGNGQFGEVWMGTWNG-TTKVAVKTLKPG-TMSPESFLEEAQIMKKLRHDKLVQLYAV-VSEEPIYIVTEYMSKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDGLVCKIADFGLARLIE-DNEYTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPTSLHELMVQCWKKDPEERPTFEYLQAFL 520
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000056885.1 (SMESG000056885.1) HSP 1 Score: 1621.68 bits (4198), Expect = 0.000e+0 Identity = 885/886 (99.89%), Postives = 885/886 (99.89%), Query Frame = 3
Query: 54 MGSIQTXXXXXXXXXXXXXXEDYVDKTSQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQVSNSLSMDKSQFKTSKGNINDYKNDNAKMINKQFDQNSIMMMQKSYQVCDPTSVMSPKKKALIKSKLANDSALTGSRNKVEFEESTPDXXXXXXXXXXXXXXXXXXXQQTNTYKTSNCTSFQXXXXXXXXXXXXXXXXXXXXXXHKKALIQNPDIEQFSTLPPKDRIDMYLESLDELXXXXXXXXXETDEYDDGVESNTEEIITNADNYSVASDSPPLNRHQ-NNDKLEMYCKHFKDDGSSSQVYQSPYISSSTNNKQIISKESLCDCLNDLILQTEFMFATFPKSISDLMNLSAQLKVCQTHIELLFKCKEVSNQNDLMQAYTNLKNSINSLDCCNDTDNATFINNILKFVQESLNTLKERINYIFKND 2708
MGSIQTKQSASNSSISKNNKEDYVDKTSQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLNPIINQNNIKNKPANDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVISKKSDFNISSSSQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQVSNSLSMDKSQFKTSKGNINDYKNDNAKMINKQFDQNSIMMMQKSYQVCDPTSVMSPKKKALIKSKLANDSALTGSRNKVEFEESTPDESGVGESVLSSESTTGSLTQQTNTYKTSNCTSFQMNNYLERNNYYLSSSSLVSMMMHKKALIQNPDIEQFSTLPPKDRIDMYLESLDELNTNNKNNVNETDEYDDGVESNTEEIITNADNYSVASDSPPLNRHQ NNDKLEMYCKHFKDDGSSSQVYQSPYISSSTNNKQIISKESLCDCLNDLILQTEFMFATFPKSISDLMNLSAQLKVCQTHIELLFKCKEVSNQNDLMQAYTNLKNSINSLDCCNDTDNATFINNILKFVQESLNTLKERINYIFKND
Sbjct: 1 MGSIQTKQSASNSSISKNNKEDYVDKTSQSSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLNPIINQNNIKNKPANDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVISKKSDFNISSSSQLPMFEDVENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKLYYICFSQNVDWSYQVSNSLSMDKSQFKTSKGNINDYKNDNAKMINKQFDQNSIMMMQKSYQVCDPTSVMSPKKKALIKSKLANDSALTGSRNKVEFEESTPDESGVGESVLSSESTTGSLTQQTNTYKTSNCTSFQMNNYLERNNYYLSSSSLVSMMMHKKALIQNPDIEQFSTLPPKDRIDMYLESLDELNTNNKNNVNETDEYDDGVESNTEEIITNADNYSVASDSPPLNRHQNNNDKLEMYCKHFKDDGSSSQVYQSPYISSSTNNKQIISKESLCDCLNDLILQTEFMFATFPKSISDLMNLSAQLKVCQTHIELLFKCKEVSNQNDLMQAYTNLKNSINSLDCCNDTDNATFINNILKFVQESLNTLKERINYIFKND 886
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000042606.1 (SMESG000042606.1) HSP 1 Score: 513.072 bits (1320), Expect = 2.626e-167 Identity = 249/482 (51.66%), Postives = 329/482 (68.26%), Query Frame = 3
Query: 132 TSQSSESLLLVALYDFNATM-ESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLLRSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDVEN-----WEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQLYSKL 1559
TS + VA DF+ T +S +S+KKG+ LK Y+ W +E S GW+P+N I+ DS L ++WYHG I R E+LL SGI GS+LVR SES S++LRY+G+++H+RI D + K YY+TEN +F T++ LI +HS F DGL C LL+P PK+ + T +F EN WEIDR+EI+M +LG GQYG VYEA WK+Y++ +AVKT+K D+ + +DFL+EA +MK+L+H NLV+LLGVC +EPP Y+I E++ GNLL +LR ++ ++ P +LLYMA QIA GM YLE++NFIHRDLAARNCLVG + ++KV DFGLAR ++RDD+YTA +GAKFPIKWTAPEGLA+N+FS+KSD+WAFGV+LWELATYG++PYPGIEL DVY LEKG M+RP GCP+ +Y IM QCWQW P RPSF L+++L
Sbjct: 57 TSTEVKQTYTVAQSDFSQTQSQSPISVKKGEKLKFKGYSPDRQWVIIEKLDSSEIGWIPSNIISDFIEESQDC--------DSYLQQFKWYHGAIPRSFAEYLLNSGITGSFLVRESESNRRLRSISLRYEGKIWHFRISKDYNNK-YYVTENQRFDTISKLIDYHSKFADGLPCQLLFPAPKRAQAT---------------------VFGVGENDSADIWEIDRTEIMMKNQLGSGQYGIVYEAFWKKYSITVAVKTVKTDITV-ADDFLEEARLMKSLQHPNLVRLLGVCTQEPPNYIIAEFMENGNLLEYLRTRSKEDLPPPVLLYMAIQIAAGMEYLEQHNFIHRDLAARNCLVGQDNIVKVADFGLARCMERDDTYTAHVGAKFPIKWTAPEGLAYNQFSTKSDVWAFGVLLWELATYGMTPYPGIELQDVYVYLEKGNIMNRPAGCPDNIYDIMKQCWQWFPESRPSFKDLHNEL 507
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000016930.1 (SMESG000016930.1) HSP 1 Score: 335.88 bits (860), Expect = 9.474e-104 Identity = 187/481 (38.88%), Postives = 279/481 (58.00%), Query Frame = 3
Query: 141 SSESLLLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEHLL--RSGINGSYLVRASESQPGQLSVTLRYDGRVYHYRIGF----DIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDV-----ENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQ-RDDSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQL 1547
S E+ + VAL+D+NA E ++SI+K D LK+I + + DW VE +G++P +YIA + + A W+ NI+R++ E LL + I G++L+R SE+ P QLS+++ Y+G V HYR+ + ++ + IT F + L+ +ST +GL C L P+ P+ D+ + WEI+R+ I + +KLG G +G+VY+ +W + +AVKTLK K E+FLKEA +MK L H NLV+L VC EP Y++TE ++KG+LL +LR+ + L+ M +QIA+GM YLE+ +IHRDLAARN L+G+N + K+ DFGL R IQ D+Y A+ GAKFPIKWTAPE KF+ KSD+W++G+VL+E+ T+G +P+P + +EKGYRM +P CP+ +Y +ML CW+ P RP+F L
Sbjct: 170 SVETDVFVALFDYNARDEEEISIRKADYLKVIDDSDL-DWWFVEHIGHGVKGYIPKSYIA----------------SKGSVEAEDWFFYNISRKDSERLLLLKGNIQGTFLIRGSETMPDQLSLSVNYNGTVNHYRVRKRRFPESMEEGFCITSRKMFFALPELVDFYSTEANGLCCKLTRACPRPP-----------------------PVISDLSRNTRDRWEINRNSIELLKKLGSGNFGEVYQGIWNK-TTDVAVKTLKPGTMAK-EEFLKEARIMKRLNHSNLVRLYAVCSDEP-IYIVTELMTKGSLLEYLREEGK-HTELKELMDMMSQIANGMAYLEKEGYIHRDLAARNILIGENNICKIADFGLTRVIQGSSDTYNARQGAKFPIKWTAPEAALMGKFTVKSDVWSYGIVLYEIITHGQTPFPAMNNTQTLQQVEKGYRMPKPSNCPQELYKVMLYCWEALPENRPTFKYL 606
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000020289.1 (SMESG000020289.1) HSP 1 Score: 314.694 bits (805), Expect = 5.515e-97 Identity = 185/477 (38.78%), Postives = 267/477 (55.97%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEH-LLRSG-INGSYLVRASESQPGQ--LSV---TLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDV-----ENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRD-DSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQL 1547
L+A++D+ A ++ +KKGD + L+ N DW VE + NRG+VP++++A + + WY ITR++ E LL+ G G +L+RASE+ G LSV + V HY+I ++ YIT FP++ LI ++S P+GL C+L +P K P+ D+ + WEIDRS + + +KLG GQ+G+V+ +W +AVKTLK K EDFLKEA VMK+L H NLV+L +C EP Y++TE +SKG+LL +LR + L+ +QIA+GM YLE + ++HRDLAARN LVG+ + K+ DFGLAR I + Y A G++FP+KWTAPE + KFS+KSD+W+FGV+++E+ T G P+P + + +E GYRM P+ CP +Y IMLQCW P RP+FA L
Sbjct: 66 FLIAIFDYKARTIDEIYLKKGDRVILLESND-PDWWLVEQRATGNRGYVPSSFLA----------------VEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIK-KTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPT-----------------------PIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNG-TTPVAVKTLKPGTMTK-EDFLKEAKVMKSLCHINLVRLYAICSDEP-IYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASL 498
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000020289.1 (SMESG000020289.1) HSP 1 Score: 316.62 bits (810), Expect = 7.201e-97 Identity = 185/477 (38.78%), Postives = 267/477 (55.97%), Query Frame = 3
Query: 156 LLVALYDFNATMESQLSIKKGDCLKLISYNHIGDWSEVESFTSHNRGWVPTNYIARLXXXXXXXXXXXXXXXDSQLMAYQWYHGNITRQEGEH-LLRSG-INGSYLVRASESQPGQ--LSV---TLRYDGRVYHYRIGFDIDKKLYYITENHKFPTVAFLIQHHSTFPDGLICALLYPVPKKVRTTNNEKVXXXXXXXXXXXXXQLPMFEDV-----ENWEIDRSEILMHQKLGGGQYGDVYEAVWKRYNVVIAVKTLKEDLNLKIEDFLKEALVMKNLRHKNLVQLLGVCIKEPPFYLITEYISKGNLLHFLRKCNQLEVTPSILLYMATQIADGMTYLEENNFIHRDLAARNCLVGDNYLLKVGDFGLARYIQRD-DSYTAKIGAKFPIKWTAPEGLAFNKFSSKSDIWAFGVVLWELATYGLSPYPGIELHDVYHILEKGYRMDRPEGCPEIVYGIMLQCWQWDPLLRPSFAQL 1547
L+A++D+ A ++ +KKGD + L+ N DW VE + NRG+VP++++A + + WY ITR++ E LL+ G G +L+RASE+ G LSV + V HY+I ++ YIT FP++ LI ++S P+GL C+L +P K P+ D+ + WEIDRS + + +KLG GQ+G+V+ +W +AVKTLK K EDFLKEA VMK+L H NLV+L +C EP Y++TE +SKG+LL +LR + L+ +QIA+GM YLE + ++HRDLAARN LVG+ + K+ DFGLAR I + Y A G++FP+KWTAPE + KFS+KSD+W+FGV+++E+ T G P+P + + +E GYRM P+ CP +Y IMLQCW P RP+FA L
Sbjct: 134 FLIAIFDYKARTIDEIYLKKGDRVILLESND-PDWWLVEQRATGNRGYVPSSFLA----------------VEYSFESQDWYFPFITRKDAERSLLQPGNARGCFLIRASETTQGAQCLSVLDHPVNSGYVVNHYKIK-KTNQGAVYITTKKIFPSLTQLILYYSNAPNGLCCSLSHPCSKPT-----------------------PIISDLSYKTKDKWEIDRSSLQLSEKLGAGQFGEVWRGLWNG-TTPVAVKTLKPGTMTK-EDFLKEAKVMKSLCHINLVRLYAICSDEP-IYIVTELMSKGSLLQYLRSETGQAMILKQLIDFISQIANGMAYLENSGYVHRDLAARNILVGEGEICKIADFGLARLIDAGCEMYEASQGSRFPVKWTAPEAALWGKFSTKSDVWSFGVLIYEIITRGQVPFPSMSNSEALQNIETGYRMPSPKQCPSYIYEIMLQCWNLRPEHRPTFASL 566 The following BLAST results are available for this feature:
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Tyrosine-protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024067 ID=SMED30024067|Name=Tyrosine-protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=2737bpback to top protein sequence of SMED30024067-orf-1 >SMED30024067-orf-1 ID=SMED30024067-orf-1|Name=SMED30024067-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=886bp MGSIQTKQSASNSSISKNNKEDYVDKTSQSSESLLLVALYDFNATMESQLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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