Serine/Threonine kinase domain protein

Overview
NameSerine/Threonine kinase domain protein
Smed IDSMED30024035
Length (bp)2341
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Serine/Threonine kinase domain protein (SMED30024035) t-SNE clustered cells

Violin plots show distribution of expression levels for Serine/Threonine kinase domain protein (SMED30024035) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Serine/Threonine kinase domain protein (SMED30024035) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Serine/Threonine kinase domain protein (SMED30024035) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30024035

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30024035h1SMcG0002047 Contig4711newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30024035h1SMcG0002047 Contig4711uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30024035h1SMcG0007492 dd_Smed_v4_5501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30024035h1SMcG0007492 dd_Smed_v4_5501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30024035h1SMcG0007492 dd_Smed_v4_5501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30024035h1SMcG0007492 dd_Smed_v4_5501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30024035h1SMcG0007492 Contig4711newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30024035h1SMcG0007492 Contig4711uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30024035h1SMcG0007492 dd_Smed_v4_5501_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Human
Match: STK4 (serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408])

HSP 1 Score: 113.62 bits (283), Expect = 5.503e-26
Identity = 82/259 (31.66%), Postives = 123/259 (47.49%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            +L+KL EG++G+V+      + + V  +   P ES    I ++ SI    +    +  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+       DF+  CL   PE+R  A +LL   F+R
Sbjct:   32 VLEKLGEGSYGSVYKAIHKETGQIVA-IKQVPVESDLQEIIKEISIMQQCDSPHVVK-YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVR 282
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Human
Match: STK4 (serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408])

HSP 1 Score: 113.62 bits (283), Expect = 7.509e-26
Identity = 82/259 (31.66%), Postives = 123/259 (47.49%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            +L+KL EG++G+V+      + + V  +   P ES    I ++ SI    +    +  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+       DF+  CL   PE+R  A +LL   F+R
Sbjct:   32 VLEKLGEGSYGSVYKAIHKETGQIVA-IKQVPVESDLQEIIKEISIMQQCDSPHVV-KYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVR 282
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Human
Match: STK3 (serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:11406])

HSP 1 Score: 112.849 bits (281), Expect = 1.697e-25
Identity = 84/260 (32.31%), Postives = 126/260 (48.46%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L   EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI++
Sbjct:   57 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCD-SPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKN 308
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Human
Match: STK3 (serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:11406])

HSP 1 Score: 112.464 bits (280), Expect = 2.022e-25
Identity = 84/260 (32.31%), Postives = 126/260 (48.46%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L   EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI++
Sbjct:   29 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCD-SPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKN 280
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Human
Match: MAP3K5 (mitogen-activated protein kinase kinase kinase 5 [Source:HGNC Symbol;Acc:HGNC:6857])

HSP 1 Score: 112.079 bits (279), Expect = 1.526e-24
Identity = 81/262 (30.92%), Postives = 133/262 (50.76%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDILSK-RFVLK-VPNKPT---ESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGL---SIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNA--KIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQP--YTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            L +G +G V+   D+ ++ R  +K +P + +   + ++ + ++   ++    +  Y G +  N  I I M+ +  GSL   +  + G    + + I   + QILE L   H   I+HRDIK +N++++  Y+   KI DFG +K +     N   E       GTL YMA E+++  P  Y    DIWS G  +IEMATG  P+Y+     A    +   +V  ++P+S   E K FI  C E  P+KR  A +LLV +F++
Sbjct:  686 LGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQ-YLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLIN-TYSGVLKISDFGTSKRLA--GINPCTETFT----GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLK 939
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Celegans
Match: cst-2 (Caenorhabditis STE20-like kinase [Source:UniProtKB/TrEMBL;Acc:Q304D8])

HSP 1 Score: 114.39 bits (285), Expect = 8.619e-27
Identity = 86/269 (31.97%), Postives = 134/269 (49.81%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVF--ICEDILSKRFVLKVP-NKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE*MELI 2274
            I+ KL EG++G+V   I  +      + KVP +   + I ++ SI    +  +++  YYG Y  ++ + I M+    GS+   +  ++K LS +EI+ +    L+ L   H L  +HRDIK+ NI+L+ +  AK+ DFG+A  + D    +          GT  +MA E++    Y  K DIWS GI  IEMA G  PY    P  A   +  K    +K P+    E  DFI +CL   PE+R  A  L    FI++    + M+L+
Sbjct:   37 IVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKS-KYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFIKNAPGCDIMQLM 298
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31])

HSP 1 Score: 114.005 bits (284), Expect = 2.288e-26
Identity = 86/269 (31.97%), Postives = 134/269 (49.81%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVF--ICEDILSKRFVLKVP-NKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE*MELI 2274
            I+ KL EG++G+V   I  +      + KVP +   + I ++ SI    +  +++  YYG Y  ++ + I M+    GS+   +  ++K LS +EI+ +    L+ L   H L  +HRDIK+ NI+L+ +  AK+ DFG+A  + D    +          GT  +MA E++    Y  K DIWS GI  IEMA G  PY    P  A   +  K    +K P+    E  DFI +CL   PE+R  A  L    FI++    + M+L+
Sbjct:   37 IVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKS-KYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFIKNAPGCDIMQLM 298
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31])

HSP 1 Score: 114.005 bits (284), Expect = 2.350e-26
Identity = 86/269 (31.97%), Postives = 134/269 (49.81%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVF--ICEDILSKRFVLKVP-NKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE*MELI 2274
            I+ KL EG++G+V   I  +      + KVP +   + I ++ SI    +  +++  YYG Y  ++ + I M+    GS+   +  ++K LS +EI+ +    L+ L   H L  +HRDIK+ NI+L+ +  AK+ DFG+A  + D    +          GT  +MA E++    Y  K DIWS GI  IEMA G  PY    P  A   +  K    +K P+    E  DFI +CL   PE+R  A  L    FI++    + M+L+
Sbjct:   37 IVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKS-KYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFIKNAPGCDIMQLM 298
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Celegans
Match: air-1 (Aurora/Ipl1 Related kinase; Aurora/Ipl1-related protein kinase 1 [Source:UniProtKB/TrEMBL;Acc:G5EDL3])

HSP 1 Score: 107.457 bits (267), Expect = 4.129e-25
Identity = 76/290 (26.21%), Postives = 138/290 (47.59%), Query Frame = 1 
Query: 1432 IDMSFVELVLNIDGVKILDKLAEGAFGTVFICEDILSKRFV-LKVPNKP-------TESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEI--ANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE*MEL 2271
            +D +  E   ++D   +   L +G FG VFI  +  +KR + LKV  K        +  + R+  I+  +     +   YG +H +  + + +   S+G L   ++ Q G  + E+       Q+   L   H   ++HRDIK EN++LD   N K+ DFG +  V D S    +        GT+ Y+A E+++NQP+   +DIW+ GIL+ EM  G  P+   T     + + + KE +  +P          IN  ++  P++R+   +++   +I++   +E +E+
Sbjct:   30 VDQAREESCWSLDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNIL-TLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWS-VVADHSKRHTL-------CGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAPFANQT---GDKLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLVDIMAHPWIKEMKQREDIEV 307
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Celegans
Match: air-1 (Aurora/Ipl1 Related kinase; Aurora/Ipl1-related protein kinase 1 [Source:UniProtKB/TrEMBL;Acc:G5EDL3])

HSP 1 Score: 107.457 bits (267), Expect = 4.129e-25
Identity = 76/290 (26.21%), Postives = 138/290 (47.59%), Query Frame = 1 
Query: 1432 IDMSFVELVLNIDGVKILDKLAEGAFGTVFICEDILSKRFV-LKVPNKP-------TESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEI--ANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE*MEL 2271
            +D +  E   ++D   +   L +G FG VFI  +  +KR + LKV  K        +  + R+  I+  +     +   YG +H +  + + +   S+G L   ++ Q G  + E+       Q+   L   H   ++HRDIK EN++LD   N K+ DFG +  V D S    +        GT+ Y+A E+++NQP+   +DIW+ GIL+ EM  G  P+   T     + + + KE +  +P          IN  ++  P++R+   +++   +I++   +E +E+
Sbjct:   30 VDQAREESCWSLDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRHPNIL-TLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFGWS-VVADHSKRHTL-------CGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAPFANQT---GDKLIARIKECKIYIPSVVTDGAASLINAIIKKEPQERLPLVDIMAHPWIKEMKQREDIEV 307
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Fly
Match: hpo (gene:FBgn0261456 transcript:FBtr0331920)

HSP 1 Score: 106.686 bits (265), Expect = 1.948e-23
Identity = 83/260 (31.92%), Postives = 124/260 (47.69%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            I+ KL EG++G+V+      S   V  +   P ES    I ++ SI    +   ++  YYG Y     + I M+    GS+   +  ++K L+  EIA I    L+ L   H    +HRDIK+ NI+L+    AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  +EMA G  PY +  P  A   + +K    ++ P     E  DF++ CL   P+ R  A ELL  +FIR+
Sbjct:   44 IMYKLGEGSYGSVYKAVHKESSSIV-AIKLVPVESDLHEIIKEISIMQQCD-SPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFIRN 295
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Fly
Match: hpo (gene:FBgn0261456 transcript:FBtr0086500)

HSP 1 Score: 106.686 bits (265), Expect = 1.948e-23
Identity = 83/260 (31.92%), Postives = 124/260 (47.69%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            I+ KL EG++G+V+      S   V  +   P ES    I ++ SI    +   ++  YYG Y     + I M+    GS+   +  ++K L+  EIA I    L+ L   H    +HRDIK+ NI+L+    AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  +EMA G  PY +  P  A   + +K    ++ P     E  DF++ CL   P+ R  A ELL  +FIR+
Sbjct:   44 IMYKLGEGSYGSVYKAVHKESSSIV-AIKLVPVESDLHEIIKEISIMQQCD-SPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFIRN 295
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Fly
Match: grp (gene:FBgn0261278 transcript:FBtr0080886)

HSP 1 Score: 100.523 bits (249), Expect = 7.334e-22
Identity = 66/207 (31.88%), Postives = 104/207 (50.24%), Query Frame = 1 
Query: 1465 IDGVKILDKLAEGAFGTVFI------CEDILSKRFVLKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPY 2067
            ++G  +   L EGA+G V +       E +  K   LK       S+ ++  I+ M++ D+ I  ++G     +   I ++  + G L   IE   G+   E      Q+L  L+  HQ  I HRD+K EN++LDE+ N KI DFG+A     F C K  ERL +   GTL Y+A E+L    +    D+WS G++++ M  G +P+
Sbjct:   19 VEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKMLQ-DKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMATM---FRC-KGKERLLDKRCGTLPYVAPEVLQKAYHAQPADLWSCGVILVTMLAGELPW 220
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Fly
Match: grp (gene:FBgn0261278 transcript:FBtr0080885)

HSP 1 Score: 100.523 bits (249), Expect = 7.334e-22
Identity = 66/207 (31.88%), Postives = 104/207 (50.24%), Query Frame = 1 
Query: 1465 IDGVKILDKLAEGAFGTVFI------CEDILSKRFVLKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPY 2067
            ++G  +   L EGA+G V +       E +  K   LK       S+ ++  I+ M++ D+ I  ++G     +   I ++  + G L   IE   G+   E      Q+L  L+  HQ  I HRD+K EN++LDE+ N KI DFG+A     F C K  ERL +   GTL Y+A E+L    +    D+WS G++++ M  G +P+
Sbjct:   19 VEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKMLQ-DKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMATM---FRC-KGKERLLDKRCGTLPYVAPEVLQKAYHAQPADLWSCGVILVTMLAGELPW 220
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Fly
Match: grp (gene:FBgn0261278 transcript:FBtr0080884)

HSP 1 Score: 100.523 bits (249), Expect = 7.334e-22
Identity = 66/207 (31.88%), Postives = 104/207 (50.24%), Query Frame = 1 
Query: 1465 IDGVKILDKLAEGAFGTVFI------CEDILSKRFVLKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPY 2067
            ++G  +   L EGA+G V +       E +  K   LK       S+ ++  I+ M++ D+ I  ++G     +   I ++  + G L   IE   G+   E      Q+L  L+  HQ  I HRD+K EN++LDE+ N KI DFG+A     F C K  ERL +   GTL Y+A E+L    +    D+WS G++++ M  G +P+
Sbjct:   19 VEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKMLQ-DKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMATM---FRC-KGKERLLDKRCGTLPYVAPEVLQKAYHAQPADLWSCGVILVTMLAGELPW 220
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Zebrafish
Match: stk3 (serine/threonine kinase 3 (STE20 homolog, yeast) [Source:NCBI gene;Acc:324125])

HSP 1 Score: 114.39 bits (285), Expect = 3.360e-26
Identity = 83/258 (32.17%), Postives = 125/258 (48.45%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA +    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI
Sbjct:   28 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPEHWSDDFTDFVKKCLVKNPEQRATATQLLQHPFI 277
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Zebrafish
Match: stk3 (serine/threonine kinase 3 (STE20 homolog, yeast) [Source:NCBI gene;Acc:324125])

HSP 1 Score: 114.39 bits (285), Expect = 3.360e-26
Identity = 83/258 (32.17%), Postives = 125/258 (48.45%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA +    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI
Sbjct:   28 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPEHWSDDFTDFVKKCLVKNPEQRATATQLLQHPFI 277
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Zebrafish
Match: stk24a (serine/threonine kinase 24a (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-070424-52])

HSP 1 Score: 107.457 bits (267), Expect = 2.790e-24
Identity = 87/283 (30.74%), Postives = 135/283 (47.70%), Query Frame = 1 
Query: 1483 LDKLAEGAFGTVFICEDILSKRFV------LKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSP--LE------LKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE--*MELISKF 2283
            L+++ +G+FG VF   D  +++ V      L+      E I ++ ++ S  +   FI  Y+G Y  +  + I M+ +  GS    +     L    IA I  +IL+ LD  H    +HRDIK+ N++L E  + K+ DFG+A  + D          +    GT  +MA E++    Y +K DIWS GI  IE+A G  P+    P           +V + +PK +P  LE      LK+F++ CL   P  R  A+ELL  K I  +  K    M+LI K+
Sbjct:   20 LERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEVEDIQQEITVLSQCDS-LFITKYFGSYLKDTKLWIIMEYLGGGSALDLL-GPGALDETHIATILREILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIK------RNTFVGTPFWMAPEVIKQSEYDSKADIWSLGITAIELAKGEPPHSDLHPM----------KVLFLIPKENPPTLEGNYNKALKEFVDACLNKDPNFRPTAKELLKHKLIVRYSKKTSYLMDLIDKY 284
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Zebrafish
Match: stk24b (serine/threonine kinase 24b (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-040426-2841])

HSP 1 Score: 104.76 bits (260), Expect = 1.944e-23
Identity = 88/283 (31.10%), Postives = 135/283 (47.70%), Query Frame = 1 
Query: 1483 LDKLAEGAFGTVFICEDILSKRFV------LKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSP--LE------LKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE--*MELISKF 2283
            L+++ +G+FG VF   D  +++ V      L+      E I ++ ++ S  +   F+  YYG Y  +  + I M+ +  GS    +E    L   +IA I  +IL+ L+  H    +HRDIK+ N++L E    K+ DFG+A  + D          +    GT  +MA E++    Y +K DIWS GI  IE+A G  P+    P           +V + +PK++P  LE      LK+F+  CL   P  R  A+ELL  K I  F  K     ELI K+
Sbjct:   15 LERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCD-SPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEP-GSLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIK------RNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPM----------KVLFLIPKNNPPTLEGNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIVRFAKKTSYLTELIDKY 279
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Zebrafish
Match: stk26 (serine/threonine protein kinase 26 [Source:ZFIN;Acc:ZDB-GENE-080516-5])

HSP 1 Score: 103.99 bits (258), Expect = 3.042e-23
Identity = 81/272 (29.78%), Postives = 128/272 (47.06%), Query Frame = 1 
Query: 1483 LDKLAEGAFGTVFICEDILSKRFV------LKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLEL--------KDFINNCLEFIPEKRMNARELLVTKFIRDFHSK 2256
            LD++ +G+FG VF   D  ++  V      L+      E I ++ ++ S  +    +  YYG Y   + + I M+ +  GS    + +       +IA +  +IL+ LD  H    +HRDIK+ N++L E+   K+ DFG+A  + D          +E   GT  +MA E++    Y +K DIWS GI  IE+A G  P     P            V + +PK++P  L        K+F+++CL   P  R  A+ELL  KFI  +  K
Sbjct:   27 LDRIGKGSFGEVFKGIDRQTQNVVAIKTIDLEEAEDEIEDIQQEITVLSQCDSPH-VTKYYGSYLKGSKLWIIMEYLGGGSALDLL-RAGPFDEYQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIK------RETFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPM----------RVLFHIPKNTPPTLNGDFSKIFKEFVDSCLNKDPAFRPTAKELLKHKFIVKYAKK 280
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Xenopus
Match: elp4 (elongator acetyltransferase complex subunit 4 [Source:Xenbase;Acc:XB-GENE-991975])

HSP 1 Score: 118.627 bits (296), Expect = 8.974e-28
Identity = 85/260 (32.69%), Postives = 128/260 (49.23%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+ +EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    E  DF+  CL   PE+R  A +LL   FI++
Sbjct:   30 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCD-SHYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEEEIATILRSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDEFTDFVKKCLVKNPEQRATATQLLQHPFIKN 281
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Xenopus
Match: elp4 (elongator acetyltransferase complex subunit 4 [Source:Xenbase;Acc:XB-GENE-991975])

HSP 1 Score: 117.472 bits (293), Expect = 3.624e-27
Identity = 85/260 (32.69%), Postives = 128/260 (49.23%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+ +EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    E  DF+  CL   PE+R  A +LL   FI++
Sbjct:   28 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCD-SHYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEEEIATILRSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDEFTDFVKKCLVKNPEQRATATQLLQHPFIKN 279
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Xenopus
Match: elp4 (elongator acetyltransferase complex subunit 4 [Source:Xenbase;Acc:XB-GENE-991975])

HSP 1 Score: 117.857 bits (294), Expect = 3.706e-27
Identity = 85/260 (32.69%), Postives = 128/260 (49.23%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+ +EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    E  DF+  CL   PE+R  A +LL   FI++
Sbjct:   33 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCD-SHYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEEEIATILRSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDEFTDFVKKCLVKNPEQRATATQLLQHPFIKN 284
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Xenopus
Match: elp4 (elongator acetyltransferase complex subunit 4 [Source:Xenbase;Acc:XB-GENE-991975])

HSP 1 Score: 117.472 bits (293), Expect = 3.926e-27
Identity = 85/260 (32.69%), Postives = 128/260 (49.23%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+ +EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    E  DF+  CL   PE+R  A +LL   FI++
Sbjct:   26 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCD-SHYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEEEIATILRSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDEFTDFVKKCLVKNPEQRATATQLLQHPFIKN 277
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Xenopus
Match: elp4 (elongator acetyltransferase complex subunit 4 [Source:Xenbase;Acc:XB-GENE-991975])

HSP 1 Score: 117.472 bits (293), Expect = 4.579e-27
Identity = 85/260 (32.69%), Postives = 128/260 (49.23%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+ +EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    E  DF+  CL   PE+R  A +LL   FI++
Sbjct:   25 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCD-SHYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEEEIATILRSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDEFTDFVKKCLVKNPEQRATATQLLQHPFIKN 276
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Mouse
Match: Stk3 (serine/threonine kinase 3 [Source:MGI Symbol;Acc:MGI:1928487])

HSP 1 Score: 115.546 bits (288), Expect = 1.362e-26
Identity = 84/260 (32.31%), Postives = 127/260 (48.85%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI++
Sbjct:   27 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQHPFIKN 278
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Mouse
Match: Stk3 (serine/threonine kinase 3 [Source:MGI Symbol;Acc:MGI:1928487])

HSP 1 Score: 115.161 bits (287), Expect = 1.710e-26
Identity = 84/260 (32.31%), Postives = 127/260 (48.85%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI++
Sbjct:   29 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQHPFIKN 280
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Mouse
Match: Stk4 (serine/threonine kinase 4 [Source:MGI Symbol;Acc:MGI:1929004])

HSP 1 Score: 111.694 bits (278), Expect = 2.390e-25
Identity = 81/259 (31.27%), Postives = 123/259 (47.49%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            +L+KL EG++G+V+      + + V  +   P ES    I ++ SI    +    +  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+       DF+  CL   PE+R  A +LL   F++
Sbjct:   32 VLEKLGEGSYGSVYKAIHKETGQIVA-IKQVPVESDLQEIIKEISIMQQCDSPHVVK-YYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFMDFVKQCLVKSPEQRATATQLLQHPFVK 282
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Mouse
Match: Map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:MGI Symbol;Acc:MGI:1346876])

HSP 1 Score: 111.694 bits (278), Expect = 1.614e-24
Identity = 80/262 (30.53%), Postives = 133/262 (50.76%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDILSK-RFVLK-VPNKPT---ESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGL---SIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNA--KIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQP--YTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            L +G +G V+   D+ ++ R  +K +P + +   + ++ + ++   ++    +  Y G +  N  I I M+ +  GSL   +  + G    + + I   + QILE L   H   I+HRDIK +N++++  Y+   KI DFG +K +     N   E       GTL YMA E+++  P  Y    DIWS G  +IEMATG  P+Y+     A    +   +V  ++P+S   E K FI  C E  P+KR  A +LL+ +F++
Sbjct:  693 LGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQ-YLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLIN-TYSGVLKISDFGTSKRLAGI--NPCTETFT----GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFLK 946
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Mouse
Match: Map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:MGI Symbol;Acc:MGI:1346876])

HSP 1 Score: 111.309 bits (277), Expect = 1.832e-24
Identity = 80/262 (30.53%), Postives = 133/262 (50.76%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDILSK-RFVLK-VPNKPT---ESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGL---SIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNA--KIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQP--YTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            L +G +G V+   D+ ++ R  +K +P + +   + ++ + ++   ++    +  Y G +  N  I I M+ +  GSL   +  + G    + + I   + QILE L   H   I+HRDIK +N++++  Y+   KI DFG +K +     N   E       GTL YMA E+++  P  Y    DIWS G  +IEMATG  P+Y+     A    +   +V  ++P+S   E K FI  C E  P+KR  A +LL+ +F++
Sbjct:  685 LGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQ-YLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLIN-TYSGVLKISDFGTSKRLAGI--NPCTETFT----GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFLK 938
[Close]
BLAST of Serine/Threonine kinase domain protein vs. UniProt/SwissProt
Match: sp|Q802A6|STK4_SQUAC (Serine/threonine-protein kinase 3/4 OS=Squalus acanthias OX=7797 GN=STK4 PE=2 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 3.495e-26
Identity = 85/260 (32.69%), Postives = 126/260 (48.46%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +    +  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    E  DF+  CL   PE+R  A +LL   FI++
Sbjct:   34 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDSPHVVK-YYGSYFKNTDLWIVMEYCGAGSVSDLIRIRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGISAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWTDEFTDFVKQCLVKNPEQRAAATQLLQHPFIKN 285
[Close]
BLAST of Serine/Threonine kinase domain protein vs. UniProt/SwissProt
Match: sp|Q6IP06|STK3_XENLA (Serine/threonine-protein kinase 3 OS=Xenopus laevis OX=8355 GN=stk3 PE=2 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 4.516e-26
Identity = 85/260 (32.69%), Postives = 127/260 (48.85%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    E  DF+  CL   PE+R  A +LL   FI++
Sbjct:   28 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDS-HYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILRSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWTDEFTDFVKKCLVKNPEQRATATQLLQHPFIKN 279
[Close]
BLAST of Serine/Threonine kinase domain protein vs. UniProt/SwissProt
Match: sp|Q9JI10|STK3_MOUSE (Serine/threonine-protein kinase 3 OS=Mus musculus OX=10090 GN=Stk3 PE=1 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 1.196e-25
Identity = 84/260 (32.31%), Postives = 127/260 (48.85%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI++
Sbjct:   29 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQHPFIKN 280
[Close]
BLAST of Serine/Threonine kinase domain protein vs. UniProt/SwissProt
Match: sp|O54748|STK3_RAT (Serine/threonine-protein kinase 3 OS=Rattus norvegicus OX=10116 GN=Stk3 PE=1 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 1.796e-25
Identity = 84/260 (32.31%), Postives = 127/260 (48.85%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRD 2244
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI++
Sbjct:   29 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDVQEIIKEISIMQQCD-SPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQHPFIKN 280
[Close]
BLAST of Serine/Threonine kinase domain protein vs. UniProt/SwissProt
Match: sp|Q7ZUQ3|STK3_DANRE (Serine/threonine-protein kinase 3 OS=Danio rerio OX=7955 GN=stk3 PE=2 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 2.537e-25
Identity = 83/258 (32.17%), Postives = 125/258 (48.45%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA +    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI
Sbjct:   28 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPEHWSDDFTDFVKKCLVKNPEQRATATQLLQHPFI 277
[Close]
BLAST of Serine/Threonine kinase domain protein vs. TrEMBL
Match: T2M6M6 (Mitogen-activated protein kinase kinase kinase 3 OS=Hydra vulgaris OX=6087 GN=MAP3K3 PE=2 SV=1)

HSP 1 Score: 139.043 bits (349), Expect = 1.607e-30
Identity = 85/265 (32.08%), Postives = 134/265 (50.57%), Query Frame = 1 
Query: 1477 KILDKLAEGAFGTVFICEDI-LSKRFVLK---------VPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            K + ++  G FGTV++C D+   K   +K            K  E + R+ S+   +  ++ +  YYG    N +I I M+ M  GS+   I K   L  KE +   +QILE ++  H  NI+HRDIK  NI+LD + N K+ DFG +K +         + +     GT  +M+ E++N   Y  K DIWS G  V+EM T   P+++  P AA  ++  +  + + LP  S +  K F+++C +  P  R NA ELL   F++
Sbjct:  368 KQVRQIGSGGFGTVYLCVDLNTGKELAMKYIETGHINTAALKEVEILQREISLYKTLNHERIVE-YYGTIQANTSISIFMEYMEGGSIHDKISKIGALDEKETSCYCFQILEGINYLHSKNIIHRDIKGANILLDSSGNCKLADFGASKQIQTIRSQTGCKSVH----GTPYWMSPEVINGAGYGRKADIWSLGCTVLEMLTTKPPWFQFEPMAALFKIATQTTIPH-LPDDSSISCKRFVDDCFKRDPSLRPNALELLSYAFVK 626
[Close]
BLAST of Serine/Threonine kinase domain protein vs. TrEMBL
Match: T1G1N2 (Protein kinase domain-containing protein OS=Helobdella robusta OX=6412 GN=20214980 PE=4 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 5.680e-29
Identity = 86/266 (32.33%), Postives = 131/266 (49.25%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDI-LSKRFVLKVPNKPTESIYRDFSIRSMIEEDQF--------IPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYA-----PGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDF 2247
            L  G FG V++C D+       +K  N   +S      +R++  E +         I  YYG       + I M+ +  GS+K  I+    L+       + Q+LE L+  H L I+HRDIK  NI+ D   N K+ DFG AK ++    NK  +  K         GT  YM+ E++  + Y  K+DIWS G  V+EM TG+ P+++    AA  ++  +    YKLP  + L++KDF++ C E  PE+R +A+ L    FIR  
Sbjct:   11 LGAGGFGQVYLCYDVDTGVELAVKQVNVYCQSEDISKEVRALQSEIKLLQDLSNPRIVQYYGSQKEPHMLSIFMEFVPGGSVKDQIQDYGPLTESVTKRYTKQVLEGLEFLHSLMIVHRDIKGANILRDHEGNIKLTDFGAAKRLSSI-VNKTADVSKNLTGAKTMTGTPYYMSPEIIEGKRYGRKVDIWSLGCTVVEMLTGHPPWHEYEGVAAIFKIATQPHPSYKLPPDTSLQVKDFLSCCFERDPERRPSAKILYNHMFIRSL 275
[Close]
BLAST of Serine/Threonine kinase domain protein vs. TrEMBL
Match: H0ZXL3 (Protein kinase domain-containing protein OS=Taeniopygia guttata OX=59729 PE=4 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 3.304e-28
Identity = 73/200 (36.50%), Postives = 111/200 (55.50%), Query Frame = 1 
Query: 1642 YYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            Y G Y  +    + M+ M  G+L   I K   LS  EIA IS + L+ LD  H  ++++RD+KS+NI+L  + + K+ DFGL      F+     +R +    GT  +MA E+L  QPY  K+DIWSFGI+ IEM  G VP+   TP +AK  + + +  + + P      L DF++ CL+   E+R +A+ LL   F++
Sbjct:   35 YLGSYLVDNQFWLVMEFMDGGTLSDVISKTY-LSEDEIAAISRECLQGLDFLHWNHVIYRDVKSDNILLRTDGSVKLADFGL------FAQLTPEQRRRSSVAGTSGWMAPEVLTGQPYGPKVDIWSFGIVGIEMVEGEVPHRNETPVSAKLLISRGERPQLRKPNRFSPHLCDFLSCCLQTDEEQRWSAKRLLQHPFVK 227
[Close]
BLAST of Serine/Threonine kinase domain protein vs. TrEMBL
Match: T1EDA5 (Protein kinase domain-containing protein OS=Helobdella robusta OX=6412 GN=20194557 PE=4 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 5.053e-28
Identity = 82/260 (31.54%), Postives = 133/260 (51.15%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDI-LSKRFVLK---VPNKPTESIYRDFS-IRSMIE------EDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            L  G+FG VF+C D+   K + +K   + +K ++   R  S +R  I       +   I  Y+G         I M+ M  GS+K  I++   L+ +   + + Q+L  L+  H+ +I+HRD+K  NI+ D   N K+ DFG +K +   S N +M+       GT+ YM+ ELL+   Y  K DIWS G  V+EM TG+ P+++    AA  +++   E  Y LP S   + +DF++ C     E+R  + +LL   F+
Sbjct:   10 LGSGSFGQVFLCCDMETGKEYAMKQVHIFSKNSQHCSRVLSALREEINILKEGVKHPHIVQYFGCQDDGVVFSILMEYMPGGSVKDQIKQYGPLTERNTISYTKQVLLGLEYLHKKSIVHRDVKGANILRDNEGNVKLSDFGASKRLQTIS-NSIMQT----QTGTIYYMSPELLDGNGYGRKTDIWSLGCSVVEMLTGHPPWHQLENFAAIFKIVTSDEPGYSLPDSVSKQARDFVSECFTRSLERRPTSSQLLYHSFV 264
[Close]
BLAST of Serine/Threonine kinase domain protein vs. TrEMBL
Match: A0A444ES81 (Protein kinase domain-containing protein OS=Ensete ventricosum OX=4639 GN=GW17_00023075 PE=4 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 2.919e-27
Identity = 65/204 (31.86%), Postives = 108/204 (52.94%), Query Frame = 1 
Query: 1648 GLYHYNATICIGMKLMSKGSLKCYIEK--QKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHS 2253
            G +      CI  + +  GSL+ ++ K   K L ++ + +I+  I   ++  H   ++HRD+K ENI+ D++   KI+DFG+A    +  C+ L E      PGT  +MA E++ ++PY  K+D++SFG+L+ EM TG +PY   TP  A   ++ K  +   +P   P  L+  I  C   +PEKR    +  + K +  F S
Sbjct:   22 GAWKQPPVFCIITEYLPGGSLRAFLRKLEHKSLPLQRLISIALDIARGMEYIHSQGVIHRDLKPENILFDQDLCIKIVDFGIA--CEEAYCDALTED-----PGTYRWMAPEMIKHKPYGRKVDVYSFGLLLWEMVTGTIPYEDMTPIQAAFAVVNKN-LRPTIPTDCPAPLRALIEQCWGVLPEKRPEFWQ--IVKVLEQFES 215
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Cavefish
Match: stk3 (serine/threonine kinase 3 [Source:NCBI gene;Acc:103027492])

HSP 1 Score: 113.62 bits (283), Expect = 4.021e-26
Identity = 84/258 (32.56%), Postives = 125/258 (48.45%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI
Sbjct:   28 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFI 277
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Cavefish
Match: STK4 (serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408])

HSP 1 Score: 111.309 bits (277), Expect = 1.678e-25
Identity = 81/253 (32.02%), Postives = 119/253 (47.04%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYI-EKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELL 2223
            +L+KL EG++G+VF      +   V  +   P ES    I ++ SI         +  YYG Y  N+ + I M+    GS+   I ++ K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+    AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P       +DF++ CL   PE R  A +LL
Sbjct:   35 VLEKLGEGSYGSVFKAHYKETGEIV-AIKQVPVESDLQEIIKEISIMQQCNSPHVV-RYYGSYFKNSDLWIVMEYCGAGSVSDIIRQRNKTLAEDEIAAILQSTLKGLEYLHFMRKIHRDIKAGNILLNSEGQAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRNPDQWSEPFRDFVSQCLVKNPENRATATQLL 279
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Cavefish
Match: map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:ZFIN;Acc:ZDB-GENE-091204-246])

HSP 1 Score: 108.227 bits (269), Expect = 1.129e-23
Identity = 83/271 (30.63%), Postives = 137/271 (50.55%), Query Frame = 1 
Query: 1462 NIDGVKILDKLAEGAFGTVFICEDILSK-RFVLK-VPNKPT---ESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISY--QILEQLDKFHQLNIMHRDIKSENIVLDENYNA--KIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQP--YTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            N +G +++  L  G +G V+   D+ ++ R  +K +P + +   + ++ + ++   +++   +  Y G    +  I I M+ +  GSL   +  + G  +KE   I Y  QILE L   H+  I+HRDIK +N++++  Y+   KI DFG +K +     N   E       GTL YMA E+++  P  Y    DIWS G  +IEMATG  P+++     A    +   ++  ++P+S   E K FI  C E  P KR  A +LL   F+R
Sbjct:  639 NENGDRVV--LGRGTYGVVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKQRNIVQ-YLGSVSEDGYIKIFMEQVPGGSLSALLRSKWG-PLKEATIIFYTRQILEGLRYLHENQIVHRDIKGDNVLVN-TYSGVLKISDFGTSKRLA--GVNPCTETFT----GTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGKPPFHELGEPQAAMFKVGMFKIHPEIPESLSTEAKSFILRCFEPDPNKRATAGDLLKDLFVR 898
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Cavefish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:103033000])

HSP 1 Score: 107.457 bits (267), Expect = 2.572e-23
Identity = 80/261 (30.65%), Postives = 125/261 (47.89%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDILSK-RFVLK-VPNKPT---ESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISY---QILEQLDKFHQLNIMHRDIKSENIVLDENYNA--KIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQP--YTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            L +G FG V+   D+ ++ R  +K +P + +   + ++ + ++   ++    +  Y G    N  I I M+ +  GSL   +  + G        I +   QILE L   H   I HRDIK +N++++  Y+   KI DFG +K +     N   E       GTL YMA E+++  P  Y    DIWS G  +IEMATG  P+Y+     A    +   ++  ++P S   E K FI  C E  P+ R  A ELL  +F+
Sbjct:  655 LGKGTFGVVYAGRDLSNQVRLAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQ-YLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILEGLKYLHDNQIAHRDIKGDNVLIN-TYSGVLKISDFGTSKRLAGI--NPCTETFT----GTLQYMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKIHPEIPDSMSSEAKAFILRCFEPDPDLRATANELLTHEFL 907
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Cavefish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:103033000])

HSP 1 Score: 107.457 bits (267), Expect = 2.612e-23
Identity = 80/261 (30.65%), Postives = 125/261 (47.89%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDILSK-RFVLK-VPNKPT---ESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISY---QILEQLDKFHQLNIMHRDIKSENIVLDENYNA--KIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQP--YTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            L +G FG V+   D+ ++ R  +K +P + +   + ++ + ++   ++    +  Y G    N  I I M+ +  GSL   +  + G        I +   QILE L   H   I HRDIK +N++++  Y+   KI DFG +K +     N   E       GTL YMA E+++  P  Y    DIWS G  +IEMATG  P+Y+     A    +   ++  ++P S   E K FI  C E  P+ R  A ELL  +F+
Sbjct:  663 LGKGTFGVVYAGRDLSNQVRLAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQ-YLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILEGLKYLHDNQIAHRDIKGDNVLIN-TYSGVLKISDFGTSKRLAGI--NPCTETFT----GTLQYMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKIHPEIPDSMSSEAKAFILRCFEPDPDLRATANELLTHEFL 915
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Sea Lamprey
Match: stk39 (serine threonine kinase 39 [Source:ZFIN;Acc:ZDB-GENE-140106-194])

HSP 1 Score: 97.4413 bits (241), Expect = 4.957e-22
Identity = 63/184 (34.24%), Postives = 98/184 (53.26%), Query Frame = 1 
Query: 1753 IANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYV---NDFSCNKLMERLKEYAPGTLSYMAIELLNN-QPYTNKIDIWSFGILVIEMATGNVPYYKATP-----------AAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE 2259
            IA+I  ++LE LD  H+   +HRD+K+ NI+L E+   +I DFG++ ++    D + NK+ +       GT  +MA E++   + Y  K DIWSFGI  +E+A+G  PY+K  P               +  ++ KE+  K  KS     +  I+ CL+  P KR  A ELL +KF +   +KE
Sbjct:    7 IASILKEVLEGLDYLHRNGQIHRDVKAGNILLGEDGTIQIADFGVSAFLATGGDVTRNKVRKTFV----GTPCWMAPEVMEQVRGYDFKADIWSFGITAMELASGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMVKKYGKS----FRKLISQCLQKDPAKRPTAAELLKSKFFQKAKNKE 182
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Sea Lamprey
Match: clul1 (clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GENE-031118-57])

HSP 1 Score: 97.0561 bits (240), Expect = 1.738e-21
Identity = 72/253 (28.46%), Postives = 126/253 (49.80%), Query Frame = 1 
Query: 1468 DGVKILDKLAEGAFGTVFICEDILSKRFVLKVPNKPT---ESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKG--LSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMAT-GNVPYYKATPAAAKQRMIKKKEVEYKL--PKSSPLELKDFINNCLEFIPEKR 2202
            D +K+  KL +G FG V+      + +  +K     T   E+   +  I   +  D+ +  Y  +      I I  + MSKGSL  ++++  G  L + ++ +++ QI   +    ++N +HRD+++ NI++ +N   KI DFGLA+ + D   N+   R     P  + + A E      +T K D+WSFGIL+ E+ T G VPY    P    + ++++ E  Y++  P S P  L + +  C +  PE+R
Sbjct:  205 DSLKLELKLGQGCFGEVWAGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSE--EPIYIVTEFMSKGSLLDFLKEGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLICKIADFGLARLIED---NEYTARQGAKFP--IKWTAPEAAMFGRFTIKSDVWSFGILLTELVTKGRVPY----PGMVNREVLEQVERGYRMPCPPSCPESLHELMMQCWKKDPEER 446
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008193.1 (pep scaffold:Pmarinus_7.0:GL476850:102262:127365:-1 gene:ENSPMAG00000007385.1 transcript:ENSPMAT00000008193.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 95.9005 bits (237), Expect = 1.946e-21
Identity = 65/248 (26.21%), Postives = 115/248 (46.37%), Query Frame = 1 
Query: 1483 LDKLAEGAFGTVFICEDILSKRFVLKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLV 2226
            L  L  GA G VF+ +       V KV  +    I     +R        I  + G+  +    CI M+  ++G L   +   + +S + +   +  I   +   H   I+HRD+KS N+++  +   KI DFG +K + + S             GT+++MA E++ N+P + K+DIWSFG+++ E+ TG +P Y+   ++A    +    +   +P S P   K  +  C    P  R + R++L+
Sbjct:   17 LQWLGSGAQGAVFLGKFRGEHVAVKKVREQKETDIKHLHKLR-----HPNIITFKGVCTHAPCYCIIMEYCAQGQLYEVLRAGRRISPELLVGWTRGIARGMSYLHLHKIIHRDLKSPNVLITHDDEVKISDFGTSKEMREKSTRMSF-------AGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP-YRDVDSSAIIWGVGSNSLHLPIPASCPEGFKILLTQCWNSKPRNRPSFRQILL 251
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92])

HSP 1 Score: 95.9005 bits (237), Expect = 3.704e-21
Identity = 81/268 (30.22%), Postives = 127/268 (47.39%), Query Frame = 1 
Query: 1486 DKLAEGAFGTVFICEDILSKRFV------LKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIK--SENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLEL--------KDFINNCLEFIPEKRMNARELLVTKFIR 2241
            +++ +G+FG VF   D  +K  V      L+      E I ++ ++ S  +   ++  Y+G Y     + I M+ +  GS    I K   L   +IA I  +IL+ LD  H    +HRDIK  + N++L E  + K+ DFG+A  + D    +          GT  +MA E++    Y  K DIWS GI  IE+A G  P  +  P            V + +PK++P  L        K+F+++CL   P+ R  A+ELL  KFI+
Sbjct:   30 ERIGKGSFGEVFKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCD-SPYVTHYFGSYLKGTKLWIIMEYLGGGSALDLI-KPGPLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDTQIKR------NTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSELHPM----------RVLFLIPKNNPPTLEGNYSKAFKEFVDSCLNKDPQFRPTAKELLKHKFIQ 279
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002088.1 (pep scaffold:Pmarinus_7.0:GL478600:446:35095:-1 gene:ENSPMAG00000001892.1 transcript:ENSPMAT00000002088.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 92.8189 bits (229), Expect = 4.644e-21
Identity = 55/197 (27.92%), Postives = 99/197 (50.25%), Query Frame = 1 
Query: 1636 PCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLV 2226
            PCY          CI M+  ++G L   +   + ++ + +   +  I   ++  H   I+HRD+KS N+++  +   KI DFG +K + D S        K    GT+++MA E++ N+P + K+DIWSFG+++ E+ TG +P Y+   ++A    +    +   +P S P   K  +  C    P  R + R++L+
Sbjct:    8 PCY----------CIIMEYCAQGQLYEVLRAGRKITPELLYRWTTGIASGMNYLHLHKIIHRDLKSPNVLITHDDLVKISDFGTSKELMDKST-------KMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP-YRDVDSSAIIWGVGSNSLHLPVPTSCPDGFKILLTQCWTGKPRNRPSFRQILL 186
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144])

HSP 1 Score: 113.235 bits (282), Expect = 3.901e-26
Identity = 90/274 (32.85%), Postives = 144/274 (52.55%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDILSKR-FVLKVPNKPTES-----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIE-LLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE*M---ELISKF 2283
            +  G FG V+   ++ + R + +KV N  ++S     + R+    + +++   I  YYG Y  + ++ I M+  + GSL+  +   K +  K I  I  ++L  L   H+ N++HRDIK+ N+++    N K+ DFG+A  VN  S      R +  A GT  +MA E ++    Y  K+DIWS GI   E+ATGN PY       A Q +IK K    +  +S    LK+FI  CL+  P++R++A +LL +KFIR   +       ELIS++
Sbjct:   29 IGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGK-IDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSL-----RRQTMA-GTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLED-RSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPTSILKELISRY 294
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Yeast
Match: MKK1 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757])

HSP 1 Score: 99.7525 bits (247), Expect = 2.265e-22
Identity = 85/282 (30.14%), Postives = 136/282 (48.23%), Query Frame = 1 
Query: 1468 DGVKILDKLAEGAFGTVFICE-DILSKRFVLKVPNK----P--TESIYRDFSIRSMIEEDQFIPCYYGLY--HYNATICIGMKLMSKGSL----KCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAA--AKQRMIK---------KKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            D ++ L  L EGA G+V  C+    SK F LKV N     P   + I+R+       +  ++I  YYG++    N++I I M+ M   SL    K  +E+   +S K +  I+  +L  L   H+  ++HRDIK +NI+L+EN   K+ DFG++         + +  L     GT  YMA E +  QPY+   D+WS G+ ++E+A G  P      AA  A   ++          K E E  +  S     K FI+ CL+    +R + R+++   +I+
Sbjct:  219 DRIETLGILGEGAGGSVSKCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQS-EYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVS--------GEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSP--SFKSFIDYCLKKDSRERPSPRQMINHPWIK 489
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124])

HSP 1 Score: 95.9005 bits (237), Expect = 1.153e-21
Identity = 63/223 (28.25%), Postives = 105/223 (47.09%), Query Frame = 1 
Query: 1477 KILDKLAEGAFGTVFICEDILSKRF----VLK----VPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEV 2121
            +I+  L  G+FG V +   + + R+    VLK    V  K  E    +  +  ++E   F+   +G +     I + M  +  G L   + K +          + +++  L+  H  NI++RD+K ENI+LD N + KI DFG AK V   +             GT  Y+A E++  +PY   +D WS G+L+ EM  G  P+Y  TP    +++++ K V
Sbjct:   71 QIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHP-FLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLC---------GTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVV 283
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 98.9821 bits (245), Expect = 1.425e-21
Identity = 78/265 (29.43%), Postives = 134/265 (50.57%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDILSKRFV----LKVP--NKPTESIYRDF-SIRSMIEE----DQF-IPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNN-QPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEV----EYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKF 2235
            + +G+FG V++C ++ +   +    ++VP  +   E+I     ++RS +      D   I  Y G  + N    + ++ ++ GS+   I          I +++ Q+L+ L   H   I+HRD+K++N++LD++   KI DFG+++   D   N  M        GT+ +MA E+++  Q Y+ K+DIWS G +V+EM  G  P+      AA  ++ K K      E  LP  S +  ++F++ C E  PEKR  A ELL   F
Sbjct: 1181 IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMR-----GTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIG-RNFLDACFEINPEKRPTANELLSHPF 1439
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Yeast
Match: SKM1 (Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473])

HSP 1 Score: 96.2857 bits (238), Expect = 4.487e-21
Identity = 80/316 (25.32%), Postives = 143/316 (45.25%), Query Frame = 1 
Query: 1399 LKENDLIDRHEIDMSFVELVLNIDG---VKILDKLAEGAFGTVFI------------------CEDILSKRFVLK---VPNKPTES-IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYI---------EKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAP--GTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            LK ND  D +EI M    + ++++     ++++K  +GA G V++                  C  ++ +R  +K   +  +P +  I  +  + +   ++  +         +  + + M+ M  G L   +         E    L+  ++A I  +  + L   H   I+HRDIKS+NI+L+     KI DFG         C +L E+  + A   GT  +MA E++N + Y  K+D+WS GI++IEM  G  PY    P  A   +      + + P+S   + K F++ CL+   E R + R+LL  +F+
Sbjct:  334 LKNND--DSNEIIMKMKTVAIDVNPRPYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILLNSQGLVKITDFGF--------CVELTEKRSKRATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL 639
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9])

HSP 1 Score: 112.849 bits (281), Expect = 2.809e-27
Identity = 81/258 (31.40%), Postives = 128/258 (49.61%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVL--KVP-NKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            +L+KL EG++G+VF      S + V   +VP +   + I ++ S+    +   ++  YYG Y  N  + I M+    GS+   ++ + K L+ +EI  +    L+ L+  H    +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  +EMA G  PY    P  A   +  K    ++ P     + KDF++ CL   PE+R  A ELL   FI+
Sbjct:   26 VLEKLGEGSYGSVFKAMHKESGQVVAIKQVPVDTDLQEIIKEISMMQQCD-SPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDLMKIRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILLNSEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEVGYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPGQWSEDFKDFVSKCLVKNPEERATATELLQHSFIQ 276
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Nematostella
Match: EDO45846 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL1])

HSP 1 Score: 106.686 bits (265), Expect = 2.273e-25
Identity = 79/271 (29.15%), Postives = 129/271 (47.60%), Query Frame = 1 
Query: 1489 KLAEGAFGTVFICEDILSKRFVL--KVPNKPTES---------IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE*ME 2268
            K+ EG+ G V +  D  + R V   K+  K  +          I RD+   +++E        YG +     + + M+ +  G+L   I     LS +++A +   +L+ L   H   ++HRDIKS++I+L  N   K+ DFG    V +      M R K    GT  +MA E+++ +PY  ++DIWS GI+V+EM  G  PY+   P  A +++   +    + P      L+ F++N L   P  R  A ELL   FIR+  +   M+
Sbjct:   34 KIGEGSTGIVCLATDKRTGRQVAVKKMDLKKQQRRELLFNEVVIMRDYPHPNIVE-------MYGSHLVGDELWVVMEFLEGGTL-TDIVTHTNLSEEQVACVCRAVLKALTFLHSQGVIHRDIKSDSILLTSNGTVKLSDFGFCAQVTED-----MPRRKSLV-GTPYWMAPEVISRKPYGTEVDIWSLGIMVLEMVDGEPPYFNEPPLQAMRKLRDLEPPTSRNPIQISPRLQSFLDNALIRDPLYRATAFELLNHPFIRNVGNSTAMQ 290
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7])

HSP 1 Score: 105.531 bits (262), Expect = 2.989e-25
Identity = 76/259 (29.34%), Postives = 124/259 (47.88%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDILSKR--FVLKVPNKPTESIYRDFSIRSMIEEDQFIPC--------YYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            L  GAFG V++C D+ + R   V ++      S  ++  ++++  E +F+          YYG+   +  I I M+ +  GS+  +I++   L+       S QILE +   H   I+HRDIK  NI+ D   N K+ DFG +K +           +     GT  +MA E++N + Y  K D+WS G  V+EM T   P+    P AA  + I  +  E +LP    ++  +F+ + L    + R +A ELL   F+
Sbjct:   10 LGAGAFGQVYMCHDLDTGRELAVKQIETGQLNSSTKN-EVKALEGEIEFMKAFRNERIVQYYGIETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYGNVKLADFGASKRLQTIRSKTGFRSVH----GTPYWMAPEVINGEGYGRKADVWSVGCTVVEMLTTKPPWADFEPMAALFK-IATQPTEPELPSDLSVDAVEFVRSTLRMNSKSRPSADELLRFSFV 262
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Nematostella
Match: EDO48026 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKQ3])

HSP 1 Score: 105.531 bits (262), Expect = 6.302e-25
Identity = 75/251 (29.88%), Postives = 116/251 (46.22%), Query Frame = 1 
Query: 1492 LAEGAFGTVFICEDI-LSKRFVLKV-------PNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVN-DFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARE 2217
            L EG++ TV++ ++I   K + +KV         K    + R+  + S +    F+  Y+  +     +  G+    KG L  YI +      K     S +I+  L+  H L I+HRD+K ENI+LDEN + KI DFG AK +N D   NK          GT  Y++ ELL ++      DIW+ G ++ ++ +G  PY         Q++IK    +Y  P   P   KD +   L   P KR+   E
Sbjct:   15 LGEGSYSTVYVAQEISTGKEYAIKVLEKRHIQKEKKVAQVSREKEVLSRLNHPFFVILYF-TFQDRDKLYFGLSYAKKGELLPYITRLGSFDEKCTQFYSAEIISALEHLHGLQIIHRDLKPENILLDENMHIKITDFGTAKILNKDEEKNKGRNSFV----GTAQYVSPELLTDKRACKSSDIWALGCIIYQLLSGLTPYRAGNEYQIFQKIIKN---DYSFPSGFPEIPKDLVEQLLILDPTKRLGCEE 257
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Nematostella
Match: EDO31934 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI4])

HSP 1 Score: 100.138 bits (248), Expect = 1.771e-22
Identity = 81/269 (30.11%), Postives = 132/269 (49.07%), Query Frame = 1 
Query: 1483 LDKLAEGAFGTVFICEDILSKRFV------LKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKE--IANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLEL--------KDFINNCLEFIPEKRMNARELLVTKFIR 2241
            L+++ +G+FG VF   D  +   V      L+      E I ++ ++ S  +   ++  Y+G Y     + I M+ +  GS    ++  K  +I+E  IA I  ++L+ LD  H    +HRDIK+ N+++ E  + K+ DFG+A  + D + NK     +    GT  +MA E++    Y +K DIWS GI  IE+A G  P     P            V + +PK++P EL        K+F++ CL   P  R  A+ELL  +FI+
Sbjct:   14 LERIGKGSFGEVFKGIDNRTNEVVAIKIIDLEEAEDEIEDIQQEITVLSQCD-SLYVTKYHGSYLKGTKLWIIMEYLGGGSA---LDLMKAGNIEEFYIATILREVLKGLDYLHTEKKLHRDIKAANVLMSETGDVKLADFGVAGQLTD-TLNK-----RNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPNSDLHPM----------RVLFLIPKNNPPELTGNFSKAFKEFVSLCLNKDPNDRPTAKELLKHRFIK 262
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Medaka
Match: ENSORLT00000044704.1 (serine/threonine-protein kinase 4 [Source:NCBI gene;Acc:101175466])

HSP 1 Score: 114.39 bits (285), Expect = 1.977e-26
Identity = 82/259 (31.66%), Postives = 123/259 (47.49%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            +L+KL EG++G VF   +      ++ +   P ES    I ++ SI         +  YYG Y  N+ + I M+    GS+   I  + K LS +EIA + +  L+ L+  H +  +HRDIK+ NI+L+    AK+ DFG+A  + D          +    GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P       +DF++ CL   PE R  A +LL   FI+
Sbjct:   35 VLEKLGEGSYGCVFKA-NYKETGEIVAIKQVPVESDLQEIIKEISIMQQCNSPHVVR-YYGSYFKNSDLWIVMEYCGAGSVSDIIRIRNKTLSEEEIATVVHSTLKGLEYLHFMRKIHRDIKAGNILLNAEGQAKLADFGVAGQLTDTMAK------RNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRNPDLWSENFRDFVSQCLVKNPENRATATQLLQHPFIK 285
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Medaka
Match: ENSORLT00000024938.2 (serine/threonine-protein kinase 4 [Source:NCBI gene;Acc:101175466])

HSP 1 Score: 114.005 bits (284), Expect = 3.129e-26
Identity = 82/259 (31.66%), Postives = 123/259 (47.49%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            +L+KL EG++G VF   +      ++ +   P ES    I ++ SI         +  YYG Y  N+ + I M+    GS+   I  + K LS +EIA + +  L+ L+  H +  +HRDIK+ NI+L+    AK+ DFG+A  + D          +    GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P       +DF++ CL   PE R  A +LL   FI+
Sbjct:   35 VLEKLGEGSYGCVFKA-NYKETGEIVAIKQVPVESDLQEIIKEISIMQQCNSPHVV-RYYGSYFKNSDLWIVMEYCGAGSVSDIIRIRNKTLSEEEIATVVHSTLKGLEYLHFMRKIHRDIKAGNILLNAEGQAKLADFGVAGQLTDTMAK------RNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRNPDLWSENFRDFVSQCLVKNPENRATATQLLQHPFIK 285
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Medaka
Match: stk3 (serine/threonine-protein kinase 3 [Source:NCBI gene;Acc:101155570])

HSP 1 Score: 114.005 bits (284), Expect = 3.218e-26
Identity = 84/258 (32.56%), Postives = 125/258 (48.45%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI
Sbjct:   32 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFI 281
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Medaka
Match: stk3 (serine/threonine-protein kinase 3 [Source:NCBI gene;Acc:101155570])

HSP 1 Score: 113.62 bits (283), Expect = 4.794e-26
Identity = 84/258 (32.56%), Postives = 125/258 (48.45%), Query Frame = 1 
Query: 1480 ILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTES----IYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIE-KQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFI 2238
            +L+KL EG++G+VF      S + V+ +   P ES    I ++ SI    +   ++  YYG Y  N  + I M+    GS+   I  + K L+  EIA I    L+ L+  H +  +HRDIK+ NI+L+   +AK+ DFG+A  + D    +          GT  +MA E++    Y    DIWS GI  IEMA G  PY    P  A   +       ++ P+    +  DF+  CL   PE+R  A +LL   FI
Sbjct:   29 VLEKLGEGSYGSVFKAIHKESGQ-VVAIKQVPVESDLQEIIKEISIMQQCDS-PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKR------NTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFI 278
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Medaka
Match: si:ch211-1i11.3 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:101167985])

HSP 1 Score: 111.694 bits (278), Expect = 1.135e-24
Identity = 93/298 (31.21%), Postives = 149/298 (50.00%), Query Frame = 1 
Query: 1399 LKENDLIDRHEIDMSFVELV--LNIDGVKILDKLAEGAFGTVFICEDILSK-RFVLK-VPNKPT---ESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKG-LSIKEIANISY--QILEQLDKFHQLNIMHRDIKSENIVLDENYNA--KIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQP--YTNKIDIWSFGILVIEMATGNVPYYK-ATPAAA--KQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            L EN   +R  +    +E V   N +G K++  L +G +G V+   D+ ++ R  +K +P K +   + ++ + ++   ++    +  Y G    +  I I M+ +  GSL   +  + G L   E   I Y  Q+LE L   H   I+HRDIK +N++++  Y+   KI DFG +K +        +    E   GTL YMA E+++  P  Y    DIWS G  +IEMATG  P+++  +P AA  K  M K   +  K+P+    E K FI +C E  P+ R  A ELL+  F++
Sbjct:  608 LAENPSQNREHLSGGVLEFVYETNENGDKVV--LGKGTYGVVYAGRDLSNQVRIAIKEIPEKDSTYSQPLHEEIALHKRLKHRNIVQ-YLGSVSQDGFIKIFMEEVPGGSLSSLLRSKWGPLKDNEPTIIFYTKQVLEGLKYLHDNQIVHRDIKGDNVLIN-TYSGVLKISDFGTSKRLAG------INPCTETFAGTLQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKTPFHELGSPQAAMFKVGMFK---IHPKVPECMSDEAKGFIMSCFEPNPDNRATAAELLMDTFLK 892
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Planmine SMEST
Match: SMESG000071539.1 (SMESG000071539.1)

HSP 1 Score: 1444.1 bits (3737), Expect = 0.000e+0
Identity = 706/717 (98.47%), Postives = 710/717 (99.02%), Query Frame = 1 
Query:  109 QYFSEVNIVNNSCSGKYLMKIYVTLEKNQDQKYVIYSDQYDAVKEIKKALCQFHKICEDVKQQYYRLIHGNIVLDEEKIIRYYNIKPNDVIWIGKLVNYVQSNDIIIEAFMIGLYTEFMFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYENLYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESMKNDIRYSILELLEFISLPKLIDTDLEYDFNKISEPFMRSRSLFYQDISNQLSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRVAQGSISLKDILTESLHLFLNILDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHGLVYHVTIPRESRTINEAKKALARQLYEPTDNLFWTQLGGDEILKENDLIDRHEIDMSFVELVLNIDGVKILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE 2259
            QY  EVNIVNNSCSGKYLMKIYVTLEKNQDQKYVIYSDQYDAVKEIKKALCQFHKICEDVKQQYYRLIHGNIVLDEEKIIRYYNIKPNDVIWIGKL NYVQSNDIIIEAFMIGLYTEFMFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYENLYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESMKNDI+YSILELLEFISLPKLIDTDLEYDFNKISEPFMRSRSLFYQDISNQLSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRVAQGSISLKDILTESL LFLN+LDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHG VYHVTIPRESRTINEAKKALARQLYEPTDNLFWT+LGGDEILKENDLIDRHEIDMSFVELVLNID VKILDKLAEGAFGTVF+CEDILSKRFVLKVP KPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE
Sbjct:   63 QYNIEVNIVNNSCSGKYLMKIYVTLEKNQDQKYVIYSDQYDAVKEIKKALCQFHKICEDVKQQYYRLIHGNIVLDEEKIIRYYNIKPNDVIWIGKLENYVQSNDIIIEAFMIGLYTEFMFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYENLYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESMKNDIKYSILELLEFISLPKLIDTDLEYDFNKISEPFMRSRSLFYQDISNQLSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRVAQGSISLKDILTESLQLFLNMLDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHGFVYHVTIPRESRTINEAKKALARQLYEPTDNLFWTELGGDEILKENDLIDRHEIDMSFVELVLNIDCVKILDKLAEGAFGTVFLCEDILSKRFVLKVPKKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE 779
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Planmine SMEST
Match: SMESG000071539.1 (SMESG000071539.1)

HSP 1 Score: 1409.43 bits (3647), Expect = 0.000e+0
Identity = 690/699 (98.71%), Postives = 694/699 (99.28%), Query Frame = 1 
Query:  163 MKIYVTLEKNQDQKYVIYSDQYDAVKEIKKALCQFHKICEDVKQQYYRLIHGNIVLDEEKIIRYYNIKPNDVIWIGKLVNYVQSNDIIIEAFMIGLYTEFMFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYENLYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESMKNDIRYSILELLEFISLPKLIDTDLEYDFNKISEPFMRSRSLFYQDISNQLSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRVAQGSISLKDILTESLHLFLNILDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHGLVYHVTIPRESRTINEAKKALARQLYEPTDNLFWTQLGGDEILKENDLIDRHEIDMSFVELVLNIDGVKILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE 2259
            MKIYVTLEKNQDQKYVIYSDQYDAVKEIKKALCQFHKICEDVKQQYYRLIHGNIVLDEEKIIRYYNIKPNDVIWIGKL NYVQSNDIIIEAFMIGLYTEFMFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYENLYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESMKNDI+YSILELLEFISLPKLIDTDLEYDFNKISEPFMRSRSLFYQDISNQLSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRVAQGSISLKDILTESL LFLN+LDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHG VYHVTIPRESRTINEAKKALARQLYEPTDNLFWT+LGGDEILKENDLIDRHEIDMSFVELVLNID VKILDKLAEGAFGTVF+CEDILSKRFVLKVP KPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE
Sbjct:    1 MKIYVTLEKNQDQKYVIYSDQYDAVKEIKKALCQFHKICEDVKQQYYRLIHGNIVLDEEKIIRYYNIKPNDVIWIGKLENYVQSNDIIIEAFMIGLYTEFMFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYENLYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESMKNDIKYSILELLEFISLPKLIDTDLEYDFNKISEPFMRSRSLFYQDISNQLSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRVAQGSISLKDILTESLQLFLNMLDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHGFVYHVTIPRESRTINEAKKALARQLYEPTDNLFWTELGGDEILKENDLIDRHEIDMSFVELVLNIDCVKILDKLAEGAFGTVFLCEDILSKRFVLKVPKKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE 699
[Close]
BLAST of Serine/Threonine kinase domain protein vs. Planmine SMEST
Match: SMESG000071539.1 (SMESG000071539.1)

HSP 1 Score: 1360.13 bits (3519), Expect = 0.000e+0
Identity = 662/671 (98.66%), Postives = 666/671 (99.25%), Query Frame = 1 
Query:  247 KKALCQFHKICEDVKQQYYRLIHGNIVLDEEKIIRYYNIKPNDVIWIGKLVNYVQSNDIIIEAFMIGLYTEFMFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYENLYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESMKNDIRYSILELLEFISLPKLIDTDLEYDFNKISEPFMRSRSLFYQDISNQLSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRVAQGSISLKDILTESLHLFLNILDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHGLVYHVTIPRESRTINEAKKALARQLYEPTDNLFWTQLGGDEILKENDLIDRHEIDMSFVELVLNIDGVKILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE 2259
            KKALCQFHKICEDVKQQYYRLIHGNIVLDEEKIIRYYNIKPNDVIWIGKL NYVQSNDIIIEAFMIGLYTEFMFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYENLYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESMKNDI+YSILELLEFISLPKLIDTDLEYDFNKISEPFMRSRSLFYQDISNQLSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRVAQGSISLKDILTESL LFLN+LDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHG VYHVTIPRESRTINEAKKALARQLYEPTDNLFWT+LGGDEILKENDLIDRHEIDMSFVELVLNID VKILDKLAEGAFGTVF+CEDILSKRFVLKVP KPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE
Sbjct:  283 KKALCQFHKICEDVKQQYYRLIHGNIVLDEEKIIRYYNIKPNDVIWIGKLENYVQSNDIIIEAFMIGLYTEFMFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYENLYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESMKNDIKYSILELLEFISLPKLIDTDLEYDFNKISEPFMRSRSLFYQDISNQLSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRVAQGSISLKDILTESLQLFLNMLDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHGFVYHVTIPRESRTINEAKKALARQLYEPTDNLFWTELGGDEILKENDLIDRHEIDMSFVELVLNIDCVKILDKLAEGAFGTVFLCEDILSKRFVLKVPKKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE 953
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BLAST of Serine/Threonine kinase domain protein vs. Planmine SMEST
Match: SMESG000071539.1 (SMESG000071539.1)

HSP 1 Score: 786.949 bits (2031), Expect = 0.000e+0
Identity = 381/388 (98.20%), Postives = 384/388 (98.97%), Query Frame = 1 
Query: 1096 TESLHLFLNILDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHGLVYHVTIPRESRTINEAKKALARQLYEPTDNLFWTQLGGDEILKENDLIDRHEIDMSFVELVLNIDGVKILDKLAEGAFGTVFICEDILSKRFVLKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE 2259
            TESL LFLN+LDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHG VYHVTIPRESRTINEAKKALARQLYEPTDNLFWT+LGGDEILKENDLIDRHEIDMSFVELVLNID VKILDKLAEGAFGTVF+CEDILSKRFVLKVP KPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE
Sbjct:    5 TESLQLFLNMLDYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHGFVYHVTIPRESRTINEAKKALARQLYEPTDNLFWTELGGDEILKENDLIDRHEIDMSFVELVLNIDCVKILDKLAEGAFGTVFLCEDILSKRFVLKVPKKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE 392
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BLAST of Serine/Threonine kinase domain protein vs. Planmine SMEST
Match: SMESG000003013.1 (SMESG000003013.1)

HSP 1 Score: 327.02 bits (837), Expect = 5.326e-101
Identity = 226/650 (34.77%), Postives = 355/650 (54.62%), Query Frame = 1 
Query:  301 YRLIHGNIVLDEEKIIRYYNIKPNDVIWIGKLVNYVQSNDIIIEAFMIGLYTEFMFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYENLYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESMKNDIRYSILELLEFISLPKL-IDTDLEYDFNKISEPFMRSRSLFYQDISNQLSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRVAQGSISLKDILTESLHLFLNIL-DYETDYREFIHSFLNEFVLNQYNNSEINGIIQNLWHDWYPRIKVKIHGLVYHVTIPRESRTINEAKKALARQLYEPTDNLFWTQLGGDEILKENDLIDRHEIDMSFVELVLNIDGVKILDKLAEGAFGTVFICEDILSKR-FVLKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHYNATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNIMHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLSYMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKKKEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIR 2241
            Y LI+ +I+L++ ++I YY I PN  I+  KL NY+Q + I++E F++    + + +I K  D I+ ++  + NI  +   +WN+ G LL  NQ + +         +I+   +  +   +   ++ D++ +  Y+ +      W+   +  S + DI  ++++  + I L    ID  LE +F      F+ SR L  + +S  +  IC + YL  LV  ++  D     R          I +++++RT    A    S++ ILT  +   +N + D   + R ++  +++EF+    N  ++N I      D Y  +K+ I    Y +T+P    T+ + K A++     P+D ++  + GGD    +ND ID   I   FVE++ + D ++    L +G+FGTVF   D  +K   +LK  +   E +YRD SI+S+IE  +       L   N  IC  M  MS GSLK  +E +K     +IA ISYQIL+Q++  H+  I+HRDIKSENIVLDE+YNAK+IDFGL+K+    S   L ERLK YAPGT+ YMA ELL ++PYTNKIDIWSFGI+++EMATGNVP Y   P     R IK K ++YK       EL +FI+  L+  P +R +A++L+ TKFI+
Sbjct:   30 YFLIYNDIILNDNRVIEYYKINPNKKIFAAKLENYLQRDHIVVEIFIMRFNPDRIHLIVKPCDTIAHIKLLLENIVADISNIWNMNGQLLAGNQSVADTANNGIDLKLIILCGDQIDIEFDKFCKIHDQFILYNYWRKYIFYDGWIRGDLFNSDR-DILMALVDKWKLILLSDFTIDCKLEKNFLHFPVGFLNSRWLACEYLSEYIYGIC-DDYLK-LVKQDIRLDGNSGFRDFIFDAIQCSILNSIKFRTA-DTAGIDKSIRTILTNGIDYLMNFINDPSFNGRYWMKLYVDEFMFAPSNTVDMNDIT----FDTYSDVKIHIDQCKYDITVPSTVETVIQLKNAISMLTGFPSDQMYLVKRGGDVKPDDNDRID--GIYNYFVEIINSFDCLQDETSLGKGSFGTVFKYVDKETKSSIILKEQHLSNEDLYRDISIQSLIERSERFINRNRLIDKNGHICFTMDYMSLGSLKSLLETKKYFPEDQIAKISYQILKQIEYIHKRYIIHRDIKSENIVLDEHYNAKLIDFGLSKFTVGLSQTSLEERLKIYAPGTVLYMAPELLMDKPYTNKIDIWSFGIVMVEMATGNVP-YSDLPQPVFIRNIKTKPIKYKASFHLSEELTNFIDCALKKDPNERFSAKQLIETKFIQ 668
The following BLAST results are available for this feature:
BLAST of Serine/Threonine kinase domain protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
STK45.503e-2631.66serine/threonine kinase 4 [Source:HGNC Symbol;Acc:... [more]
STK47.509e-2631.66serine/threonine kinase 4 [Source:HGNC Symbol;Acc:... [more]
STK31.697e-2532.31serine/threonine kinase 3 [Source:HGNC Symbol;Acc:... [more]
STK32.022e-2532.31serine/threonine kinase 3 [Source:HGNC Symbol;Acc:... [more]
MAP3K51.526e-2430.92mitogen-activated protein kinase kinase kinase 5 [... [more]
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cst-28.619e-2731.97Caenorhabditis STE20-like kinase [Source:UniProtK... [more]
cst-12.288e-2631.97Serine/threonine-protein kinase cst-1 Serine/threo... [more]
cst-12.350e-2631.97Serine/threonine-protein kinase cst-1 Serine/threo... [more]
air-14.129e-2526.21Aurora/Ipl1 Related kinase; Aurora/Ipl1-related pr... [more]
air-14.129e-2526.21Aurora/Ipl1 Related kinase; Aurora/Ipl1-related pr... [more]
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hpo1.948e-2331.92gene:FBgn0261456 transcript:FBtr0331920[more]
hpo1.948e-2331.92gene:FBgn0261456 transcript:FBtr0086500[more]
grp7.334e-2231.88gene:FBgn0261278 transcript:FBtr0080886[more]
grp7.334e-2231.88gene:FBgn0261278 transcript:FBtr0080885[more]
grp7.334e-2231.88gene:FBgn0261278 transcript:FBtr0080884[more]
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk33.360e-2632.17serine/threonine kinase 3 (STE20 homolog, yeast) [... [more]
stk33.360e-2632.17serine/threonine kinase 3 (STE20 homolog, yeast) [... [more]
stk24a2.790e-2430.74serine/threonine kinase 24a (STE20 homolog, yeast)... [more]
stk24b1.944e-2331.10serine/threonine kinase 24b (STE20 homolog, yeast)... [more]
stk263.042e-2329.78serine/threonine protein kinase 26 [Source:ZFIN;Ac... [more]
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
elp48.974e-2832.69elongator acetyltransferase complex subunit 4 [Sou... [more]
elp43.624e-2732.69elongator acetyltransferase complex subunit 4 [Sou... [more]
elp43.706e-2732.69elongator acetyltransferase complex subunit 4 [Sou... [more]
elp43.926e-2732.69elongator acetyltransferase complex subunit 4 [Sou... [more]
elp44.579e-2732.69elongator acetyltransferase complex subunit 4 [Sou... [more]
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Stk31.362e-2632.31serine/threonine kinase 3 [Source:MGI Symbol;Acc:M... [more]
Stk31.710e-2632.31serine/threonine kinase 3 [Source:MGI Symbol;Acc:M... [more]
Stk42.390e-2531.27serine/threonine kinase 4 [Source:MGI Symbol;Acc:M... [more]
Map3k51.614e-2430.53mitogen-activated protein kinase kinase kinase 5 [... [more]
Map3k51.832e-2430.53mitogen-activated protein kinase kinase kinase 5 [... [more]
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BLAST of Serine/Threonine kinase domain protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q802A6|STK4_SQUAC3.495e-2632.69Serine/threonine-protein kinase 3/4 OS=Squalus aca... [more]
sp|Q6IP06|STK3_XENLA4.516e-2632.69Serine/threonine-protein kinase 3 OS=Xenopus laevi... [more]
sp|Q9JI10|STK3_MOUSE1.196e-2532.31Serine/threonine-protein kinase 3 OS=Mus musculus ... [more]
sp|O54748|STK3_RAT1.796e-2532.31Serine/threonine-protein kinase 3 OS=Rattus norveg... [more]
sp|Q7ZUQ3|STK3_DANRE2.537e-2532.17Serine/threonine-protein kinase 3 OS=Danio rerio O... [more]
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BLAST of Serine/Threonine kinase domain protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T2M6M61.607e-3032.08Mitogen-activated protein kinase kinase kinase 3 O... [more]
T1G1N25.680e-2932.33Protein kinase domain-containing protein OS=Helobd... [more]
H0ZXL33.304e-2836.50Protein kinase domain-containing protein OS=Taenio... [more]
T1EDA55.053e-2831.54Protein kinase domain-containing protein OS=Helobd... [more]
A0A444ES812.919e-2731.86Protein kinase domain-containing protein OS=Ensete... [more]
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk34.021e-2632.56serine/threonine kinase 3 [Source:NCBI gene;Acc:10... [more]
STK41.678e-2532.02serine/threonine kinase 4 [Source:HGNC Symbol;Acc:... [more]
map3k151.129e-2330.63mitogen-activated protein kinase kinase kinase 15 ... [more]
map3k52.572e-2330.65mitogen-activated protein kinase kinase kinase 5 [... [more]
map3k52.612e-2330.65mitogen-activated protein kinase kinase kinase 5 [... [more]
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk394.957e-2234.24serine threonine kinase 39 [Source:ZFIN;Acc:ZDB-GE... [more]
clul11.738e-2128.46clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GE... [more]
ENSPMAT00000008193.11.946e-2126.21pep scaffold:Pmarinus_7.0:GL476850:102262:127365:-... [more]
stk25a3.704e-2130.22serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-G... [more]
ENSPMAT00000002088.14.644e-2127.92pep scaffold:Pmarinus_7.0:GL478600:446:35095:-1 ge... [more]
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
KIC13.901e-2632.85Protein kinase of the PAK/Ste20 family, required f... [more]
MKK12.265e-2230.14MAPKK involved in the protein kinase C signaling p... [more]
TPK21.153e-2128.25cAMP-dependent protein kinase catalytic subunit; p... [more]
BCK11.425e-2129.43MAPKKK acting in the protein kinase C signaling pa... [more]
SKM14.487e-2125.32Member of the PAK family of serine/threonine prote... [more]
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO428452.809e-2731.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO458462.273e-2529.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO414102.989e-2529.34Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO480266.302e-2529.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO319341.771e-2230.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Serine/Threonine kinase domain protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000044704.11.977e-2631.66serine/threonine-protein kinase 4 [Source:NCBI gen... [more]
ENSORLT00000024938.23.129e-2631.66serine/threonine-protein kinase 4 [Source:NCBI gen... [more]
stk33.218e-2632.56serine/threonine-protein kinase 3 [Source:NCBI gen... [more]
stk34.794e-2632.56serine/threonine-protein kinase 3 [Source:NCBI gen... [more]
si:ch211-1i11.31.135e-2431.21mitogen-activated protein kinase kinase kinase 5 [... [more]
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BLAST of Serine/Threonine kinase domain protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000071539.10.000e+098.47SMESG000071539.1[more]
SMESG000071539.10.000e+098.71SMESG000071539.1[more]
SMESG000071539.10.000e+098.66SMESG000071539.1[more]
SMESG000071539.10.000e+098.20SMESG000071539.1[more]
SMESG000003013.15.326e-10134.77SMESG000003013.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024035 ID=SMED30024035|Name=Serine/Threonine kinase domain protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2341bp
TTAAACGACGTCAATATTTTGCCATAACGACACTACTGACTACTTATAAA
ATTTATAAATAATCAGATAATATGTGAATTCACCAAAATGATTTAATGAA
TTTTTAATCAATATTTTAGTGAAGTCAACATTGTCAATAATAGTTGTAGC
GGAAAATATTTAATGAAAATTTATGTGACATTAGAGAAAAACCAGGATCA
AAAGTACGTCATTTATTCTGATCAGTATGATGCTGTTAAAGAAATCAAGA
AAGCATTATGTCAATTCCACAAAATCTGTGAAGATGTCAAACAACAATAT
TATCGATTGATTCATGGAAATATTGTGCTAGACGAGGAGAAAATTATTAG
ATATTATAATATTAAACCAAATGACGTGATCTGGATCGGAAAATTGGTAA
ACTATGTTCAAAGCAACGATATAATAATAGAAGCGTTTATGATCGGATTG
TATACTGAATTTATGTTTGTCATCTTCAAGGACTCTGATTTGATATCACA
GCTGAGATCAGCAATTCGCAATATTACCAATGAACCAATCAGAATGTGGA
ATCTTTTCGGTGATCTGCTGGAAGACAATCAATTATTAATCGAGATCGAT
AAATACGAGAATCTATATAATATAATTGTCGGATTTGAAGAATCAAACAA
TGAGAATATAGAAGATACTTATCAACTTCGTGATAGATACTTCATAAGCG
AGTATTTTTGGAGGAATCAGTTGCTCCAATGTTGGTTACATCCGATAATT
GAGGAATCAATGAAGAATGATATCAGATATTCAATCCTAGAATTATTAGA
ATTTATATCGTTACCGAAACTCATAGACACAGATCTGGAATACGATTTCA
ATAAAATCTCGGAACCTTTCATGCGTTCACGGTCTTTATTTTATCAAGAT
ATTTCCAATCAGTTATCCTTTATTTGTTACAATAAATATTTGGGAATATT
GGTTGATGATGAACTTTCAAAAGATAAAGAATTGAGAATTCGCCAAGTGT
TCAGCAGTTACTTTCTCTTAATGATACAATCTACAGTGCAATGGCGCACC
TGCTATCGCGTGGCACAAGGGTCAATTAGCTTGAAGGATATCTTAACTGA
GTCTTTGCATTTGTTTCTTAATATCCTTGATTATGAAACAGACTACCGAG
AATTTATCCATTCGTTTTTGAATGAATTTGTATTAAATCAATATAATAAC
TCTGAAATAAATGGAATTATCCAAAATCTATGGCACGATTGGTATCCGCG
TATCAAAGTAAAGATTCACGGATTAGTGTATCATGTCACAATTCCCCGAG
AGTCCCGTACAATTAATGAAGCAAAAAAAGCTTTGGCCAGGCAGCTATAT
GAGCCCACAGATAATTTGTTTTGGACTCAACTCGGCGGAGATGAAATACT
AAAAGAGAATGATTTAATAGATCGACATGAAATTGACATGTCTTTTGTGG
AACTTGTTTTGAACATAGATGGCGTAAAAATACTTGACAAACTTGCGGAA
GGTGCATTTGGTACCGTCTTTATTTGTGAAGATATTTTATCTAAAAGATT
CGTGCTGAAAGTGCCGAATAAACCAACGGAAAGCATTTATAGAGATTTCA
GTATTCGATCTATGATCGAAGAAGATCAGTTCATTCCTTGTTATTATGGG
TTATATCATTATAATGCAACAATTTGTATTGGAATGAAGTTAATGTCGAA
GGGATCATTAAAATGTTATATTGAGAAGCAAAAGGGGCTTTCTATAAAAG
AAATCGCAAATATTTCCTATCAAATTCTTGAACAGCTCGACAAATTCCAC
CAGCTGAACATCATGCATCGGGACATCAAAAGTGAAAATATCGTTCTGGA
TGAAAATTATAATGCGAAAATAATAGATTTTGGACTGGCAAAATATGTGA
ATGATTTTTCGTGTAACAAATTAATGGAACGATTAAAAGAGTATGCTCCG
GGAACCCTTAGTTACATGGCTATAGAACTGTTGAATAATCAACCATATAC
AAACAAAATTGACATTTGGTCATTTGGAATATTGGTCATTGAAATGGCTA
CAGGAAATGTTCCATATTACAAAGCCACGCCAGCAGCTGCCAAACAAAGA
ATGATAAAGAAAAAAGAGGTCGAATATAAGTTACCCAAGTCTTCGCCTTT
GGAATTAAAAGACTTTATAAATAATTGTTTGGAATTTATTCCAGAAAAAA
GAATGAATGCTAGAGAATTATTGGTGACAAAATTTATTCGTGACTTCCAT
TCCAAAGAGTAAATGGAATTAATTTCCAAATTTTGTACTTCGGCATTCAT
GATTACCTTTTAATAAAAAATTTCAATGACAGTCTAAAAAA
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protein sequence of SMED30024035-orf-1

>SMED30024035-orf-1 ID=SMED30024035-orf-1|Name=SMED30024035-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=700bp
MKIYVTLEKNQDQKYVIYSDQYDAVKEIKKALCQFHKICEDVKQQYYRLI
HGNIVLDEEKIIRYYNIKPNDVIWIGKLVNYVQSNDIIIEAFMIGLYTEF
MFVIFKDSDLISQLRSAIRNITNEPIRMWNLFGDLLEDNQLLIEIDKYEN
LYNIIVGFEESNNENIEDTYQLRDRYFISEYFWRNQLLQCWLHPIIEESM
KNDIRYSILELLEFISLPKLIDTDLEYDFNKISEPFMRSRSLFYQDISNQ
LSFICYNKYLGILVDDELSKDKELRIRQVFSSYFLLMIQSTVQWRTCYRV
AQGSISLKDILTESLHLFLNILDYETDYREFIHSFLNEFVLNQYNNSEIN
GIIQNLWHDWYPRIKVKIHGLVYHVTIPRESRTINEAKKALARQLYEPTD
NLFWTQLGGDEILKENDLIDRHEIDMSFVELVLNIDGVKILDKLAEGAFG
TVFICEDILSKRFVLKVPNKPTESIYRDFSIRSMIEEDQFIPCYYGLYHY
NATICIGMKLMSKGSLKCYIEKQKGLSIKEIANISYQILEQLDKFHQLNI
MHRDIKSENIVLDENYNAKIIDFGLAKYVNDFSCNKLMERLKEYAPGTLS
YMAIELLNNQPYTNKIDIWSFGILVIEMATGNVPYYKATPAAAKQRMIKK
KEVEYKLPKSSPLELKDFINNCLEFIPEKRMNARELLVTKFIRDFHSKE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
IPR029071Ubiquitin-like_domsf
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0004674protein serine/threonine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation