SMED30024029

Overview
NameSMED30024029
Smed IDSMED30024029
Length (bp)490
Neoblast Clusters

Zeng et. al., 2018




 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30024029

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 24

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30024029h1SMcG0013360 SmedASXL_080944SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30024029h1SMcG0013360 SmedASXL_013101SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30024029h1SMcG0013360 SmedASXL_005273SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30024029h1SMcG0013360 SmedASXL_004889SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30024029h1SMcG0013360 SmedASXL_000149SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30024029h1SMcG0013360 SmedASXL_008576SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30024029h1SMcG0013360 dd_Smed_v4_20782_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30024029h1SMcG0013360 dd_Smed_v4_20782_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30024029h1SMcG0013360 dd_Smed_v4_20782_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30024029h1SMcG0013360 dd_Smed_v4_20782_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30024029h1SMcG0013360 dd_Smed_v4_26550_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30024029h1SMcG0013360 dd_Smed_v4_21124_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30024029h1SMcG0013360 dd_Smed_v4_21124_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30024029h1SMcG0013360 dd_Smed_v4_21124_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30024029h1SMcG0013360 dd_Smed_v4_32573_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30024029h1SMcG0013360 dd_Smed_v4_32573_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30024029h1SMcG0013360 dd_Smed_v4_32573_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30024029h1SMcG0013360 dd_Smed_v4_32573_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30024029h1SMcG0013360 dd_Smed_v6_32573_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30024029h1SMcG0013360 dd_Smed_v6_41749_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30024029h1SMcG0013360 dd_Smed_v6_20782_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30024029h1SMcG0013360 dd_Smed_v6_21124_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
neuronSMED30024029h1SMcG0013360 dd_Smed_v6_32573_0_1dd_Smed_v6PMID:30399335
Ross et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30024029h1SMcG0013360 OX_Smed_1.0.08391ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30024029 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.000411:15639..16128 -2450
Homology
BLAST of SMED30024029 vs. Ensembl Human
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:29])

HSP 1 Score: 107.071 bits (266), Expect = 8.031e-27
Identity = 48/128 (37.50%), Postives = 80/128 (62.50%), Query Frame = -1
Query:  107 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 490
              F +A++A+  GGI+YF  YLP+++ V  QD +   +   A+LL+ V+      + A +E+   G+Q+ NLF+S + +  F +   + MM  D+ +Y ++ WYIE VFPGQ+G+ +PW FP T++YW
Sbjct:  738 TLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCTKSYW 865          
BLAST of SMED30024029 vs. Ensembl Human
Match: ABCA3 (ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33])

HSP 1 Score: 104.76 bits (260), Expect = 4.335e-26
Identity = 50/133 (37.59%), Postives = 76/133 (57.14%), Query Frame = -1
Query:   89 FFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGK 487
            FF KA++A+  GG LYF  Y+P+       + MT+     + LL+ V+++     I  +E    GIQ+ +L     +D +F  G  + M+ +DSV+Y L+ WY+E VFPGQFG+ +PW F    +YW   CGK
Sbjct:  367 FFSKANMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCSCLLSNVAMAMGAQLIGKFEAKGMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYGLVTWYMEAVFPGQFGVPQPWYFFIMPSYW---CGK 496          
BLAST of SMED30024029 vs. Ensembl Human
Match: ABCA7 (ATP binding cassette subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:37])

HSP 1 Score: 102.449 bits (254), Expect = 2.920e-25
Identity = 47/132 (35.61%), Postives = 77/132 (58.33%), Query Frame = -1
Query:   92 FFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICG 487
            FF +A++A+  GG+ YF  YLP+++ V  +D +      AA+LL+ V+       +A  E+  +G Q+ N+      D+ F +     ++ +D+ +Y L  WY+E V PGQ+G+ +PWNFPF R+YW   CG
Sbjct:  649 FFSRANLAAACGGLAYFSLYLPYVLCVAWRDRLPAGGRVAASLLSPVAFGFGCESLALLEEQGEGAQWHNVGTRPTADV-FSLAQVSGLLLLDAALYGLATWYLEAVCPGQYGIPEPWNFPFRRSYW---CG 776          
BLAST of SMED30024029 vs. Ensembl Human
Match: ABCA4 (ATP binding cassette subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:34])

HSP 1 Score: 102.064 bits (253), Expect = 4.227e-25
Identity = 54/168 (32.14%), Postives = 88/168 (52.38%), Query Frame = -1
Query:    2 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSN-----LDEMESFSNPLNEPIPNESLNERGFEH 490
             FF KAS+A+   G++YF  YLP ++    QD MT  +  A +LL+ V+      ++  +E+   G+Q+SN+ +S      F     M MM +D+ +Y L+AWY++ VFPG +G   PW F    +YW+   G S      L++ E  +    +P   E +++  FE 
Sbjct:  753 TFFSKASLAAACSGVIYFTLYLPHILCFAWQDRMTAELKKAVSLLSPVAFGFGTEYLVRFEEQGLGLQWSNIGNSPTEGDEFSFLLSMQMMLLDAAVYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTEPLTEETEDPEHPEGIHDSFFER 920          
BLAST of SMED30024029 vs. Ensembl Human
Match: ABCA12 (ATP binding cassette subfamily A member 12 [Source:HGNC Symbol;Acc:HGNC:14637])

HSP 1 Score: 95.1301 bits (235), Expect = 1.223e-22
Identity = 41/128 (32.03%), Postives = 77/128 (60.16%), Query Frame = -1
Query:  107 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 490
            VFF+  ++A++ G ++Y + + PF++ V +++ ++  +    +LL+  + S +  +IA +E+   G+Q+ N++ S + D     G    ++  DS IY LIAWY+  VFPG +G++ PW FP   +YW
Sbjct: 1167 VFFNNTNIAALIGSLIYIIAFFPFIVLVTVENELSYVLKVFMSLLSPTAFSYASQYIARYEEQGIGLQWENMYTSPVQDDTTSFGWLCCLILADSFIYFLIAWYVRNVFPGTYGMAAPWYFPILPSYW 1294          
BLAST of SMED30024029 vs. Ensembl Celegans
Match: abt-2 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q1RS86])

HSP 1 Score: 71.2478 bits (173), Expect = 7.249e-15
Identity = 38/129 (29.46%), Postives = 72/129 (55.81%), Query Frame = -1
Query:  107 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAAL-LTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 490
              F  A++A+ +  +L+FVF++PF +     D ++ P +   +L L   ++ +    +  +  + +   +S+L++     L   V  CM+M+ +D+ ++L++AWYI  V PG FG+ +P  FPFT  YW
Sbjct:  730 TLFTNANIATAATCVLWFVFFIPFQLLRT--DRISSPTFNRISLILPPTAMGHCFKLLESF-NAMERATWSDLWEMNNPVLGISVELCMIMLVVDTAVFLILAWYISAVAPGDFGVRQPLWFPFTLKYW 855          
BLAST of SMED30024029 vs. Ensembl Celegans
Match: abt-2 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q1RS86])

HSP 1 Score: 71.2478 bits (173), Expect = 7.612e-15
Identity = 38/129 (29.46%), Postives = 72/129 (55.81%), Query Frame = -1
Query:  107 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAAL-LTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 490
              F  A++A+ +  +L+FVF++PF +     D ++ P +   +L L   ++ +    +  +  + +   +S+L++     L   V  CM+M+ +D+ ++L++AWYI  V PG FG+ +P  FPFT  YW
Sbjct:  767 TLFTNANIATAATCVLWFVFFIPFQLLRT--DRISSPTFNRISLILPPTAMGHCFKLLESF-NAMERATWSDLWEMNNPVLGISVELCMIMLVVDTAVFLILAWYISAVAPGDFGVRQPLWFPFTLKYW 892          
BLAST of SMED30024029 vs. Ensembl Celegans
Match: abt-4 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q9TXV8])

HSP 1 Score: 65.855 bits (159), Expect = 6.400e-13
Identity = 37/147 (25.17%), Postives = 71/147 (48.30%), Query Frame = -1
Query:   56 FFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAA--ALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGL-SKPWNFPFTRNYWISICGKSNLDEMESFSN 487
            F + A+ A++   + + + Y  +  F ++  +   P+ Y     +   ++L+  +  +A +E   DG+++  LF     D N   GH ++ + +D +I +++ WYIE V PG  G+  KPW F    +YW    G   +D  + F  
Sbjct:  419 FMNSATSATLISVVFWMLLYFWYAFFSSIDQTNPYPLGYRLINCINPDIALNYGLQLLAAYETQADGLKWGELFTPPSPDNNLTFGHALIALIVDGIIMIILTWYIEAVIPGGEGVPQKPWFFVLP-SYWFPNSGSKTVDSSDQFQQ 564          
BLAST of SMED30024029 vs. Ensembl Fly
Match: ABCA (gene:FBgn0031170 transcript:FBtr0306679)

HSP 1 Score: 107.457 bits (267), Expect = 2.501e-27
Identity = 52/159 (32.70%), Postives = 88/159 (55.35%), Query Frame = -1
Query:   14 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNEPIPNESLNER 490
             FF +AS A+   G+++F+ Y+P+   +N  D +++      +L++  ++   I  I  +E + +G+Q+SN F    +D    +G  M+MM +  VIY++I  Y+E V PG FG+ +PWNFPFTR +W   CG+     +E         IPN  + +R
Sbjct:  375 TFFSRASTAAAVTGLIWFIAYIPYSFTINSYDDLSLSSKLGWSLISNTAMGFGIKLILGFEGTGEGLQWSNFFTPVSVDDTLTLGAVMIMMLVSCVIYMIICLYVEQVMPGSFGVPRPWNFPFTREFW---CGEREYTGVED--------IPNGHVEQR 522          
BLAST of SMED30024029 vs. Ensembl Fly
Match: ABCA (gene:FBgn0031170 transcript:FBtr0332489)

HSP 1 Score: 107.457 bits (267), Expect = 2.548e-27
Identity = 52/159 (32.70%), Postives = 88/159 (55.35%), Query Frame = -1
Query:   14 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNEPIPNESLNER 490
             FF +AS A+   G+++F+ Y+P+   +N  D +++      +L++  ++   I  I  +E + +G+Q+SN F    +D    +G  M+MM +  VIY++I  Y+E V PG FG+ +PWNFPFTR +W   CG+     +E         IPN  + +R
Sbjct:  353 TFFSRASTAAAVTGLIWFIAYIPYSFTINSYDDLSLSSKLGWSLISNTAMGFGIKLILGFEGTGEGLQWSNFFTPVSVDDTLTLGAVMIMMLVSCVIYMIICLYVEQVMPGSFGVPRPWNFPFTREFW---CGEREYTGVED--------IPNGHVEQR 500          
BLAST of SMED30024029 vs. Ensembl Fly
Match: ABCA (gene:FBgn0031170 transcript:FBtr0332488)

HSP 1 Score: 107.457 bits (267), Expect = 2.624e-27
Identity = 52/159 (32.70%), Postives = 88/159 (55.35%), Query Frame = -1
Query:   14 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNEPIPNESLNER 490
             FF +AS A+   G+++F+ Y+P+   +N  D +++      +L++  ++   I  I  +E + +G+Q+SN F    +D    +G  M+MM +  VIY++I  Y+E V PG FG+ +PWNFPFTR +W   CG+     +E         IPN  + +R
Sbjct:  353 TFFSRASTAAAVTGLIWFIAYIPYSFTINSYDDLSLSSKLGWSLISNTAMGFGIKLILGFEGTGEGLQWSNFFTPVSVDDTLTLGAVMIMMLVSCVIYMIICLYVEQVMPGSFGVPRPWNFPFTREFW---CGEREYTGVED--------IPNGHVEQR 500          
BLAST of SMED30024029 vs. Ensembl Fly
Match: CG6052 (gene:FBgn0036747 transcript:FBtr0075195)

HSP 1 Score: 72.0182 bits (175), Expect = 6.126e-15
Identity = 41/133 (30.83%), Postives = 71/133 (53.38%), Query Frame = -1
Query:  107 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNS-----INFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 490
            V F KAS AS    I +F+ Y+P+       + +++     + LL  +  SNS     I+ I  WE + +GI + N+F     D +  + + ++ M   S++++ I  Y+E VFPG++G+ + WNF   +NYW
Sbjct:  353 VLFSKASTASAVAAIFWFLTYIPYSFGYYYYERLSL----MSKLLISLIFSNSALGFGIHVIVMWEGTGEGITWRNMFHPVSTDDSLTLFYIIMTMSFGSIMFISICLYVEQVFPGEYGVPRRWNFMCHKNYW 481          
BLAST of SMED30024029 vs. Ensembl Fly
Match: CG31213 (gene:FBgn0051213 transcript:FBtr0335242)

HSP 1 Score: 56.6102 bits (135), Expect = 1.128e-9
Identity = 41/119 (34.45%), Postives = 67/119 (56.30%), Query Frame = -1
Query:  107 VSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFG-VGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 460
            V+  ++YF   LPFLI V  ++S +V    AA++    +L   ++ +A  E  + G Q+  + ++A        VG+ ++M+ I S I LLI  YIE V  G+F + +PW++PF R YW
Sbjct:  317 VATILMYFSTALPFLI-VGAENS-SVAAQTAASIGLNSALFYILDSVAVMEMQSVGAQWYTIDNTASSGYKLSIVGYMLIMISI-SWIELLICLYIEAVRTGEFEVPQPWSYPFQRRYW 432          
BLAST of SMED30024029 vs. Ensembl Zebrafish
Match: abca1b (ATP-binding cassette, sub-family A (ABC1), member 1B [Source:ZFIN;Acc:ZDB-GENE-030131-9826])

HSP 1 Score: 109.768 bits (273), Expect = 5.975e-28
Identity = 47/116 (40.52%), Postives = 78/116 (67.24%), Query Frame = -1
Query:  107 GGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 454
            GGI+YF  YLP+++ V  QD +       A+LL+ V+      + A +E+   GIQ++NLF S + + ++ +  C+++M+ D+ +Y ++ WYIETVFPGQ+G+ +PW FPFT++YW
Sbjct:  753 GGIIYFTLYLPYVLCVAWQDYVGFAAKVIASLLSPVAFGFGCEYFALFEEQGVGIQWNNLFSSPVEEDDYNLTTCLILMYFDAFLYGVMTWYIETVFPGQYGIPRPWYFPFTKSYW 868          
BLAST of SMED30024029 vs. Ensembl Zebrafish
Match: abca1b (ATP-binding cassette, sub-family A (ABC1), member 1B [Source:ZFIN;Acc:ZDB-GENE-030131-9826])

HSP 1 Score: 109.768 bits (273), Expect = 6.091e-28
Identity = 47/116 (40.52%), Postives = 78/116 (67.24%), Query Frame = -1
Query:  107 GGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 454
            GGI+YF  YLP+++ V  QD +       A+LL+ V+      + A +E+   GIQ++NLF S + + ++ +  C+++M+ D+ +Y ++ WYIETVFPGQ+G+ +PW FPFT++YW
Sbjct:  753 GGIIYFTLYLPYVLCVAWQDYVGFAAKVIASLLSPVAFGFGCEYFALFEEQGVGIQWNNLFSSPVEEDDYNLTTCLILMYFDAFLYGVMTWYIETVFPGQYGIPRPWYFPFTKSYW 868          
BLAST of SMED30024029 vs. Ensembl Zebrafish
Match: abca1a (ATP-binding cassette, sub-family A (ABC1), member 1A [Source:ZFIN;Acc:ZDB-GENE-031006-12])

HSP 1 Score: 108.997 bits (271), Expect = 1.088e-27
Identity = 50/135 (37.04%), Postives = 83/135 (61.48%), Query Frame = -1
Query:   86 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKS 490
              F +A++A+  GGI+YF  YLP+++ V  Q+ +        +LL+ V+      + A +E+   GIQ+SNL  S + + ++ +   + +M  DSV+Y ++ WYIE VFPGQ+G+ +PW FPFT++YW   CG+ 
Sbjct:  742 TLFSRANLAAACGGIIYFTLYLPYVLCVAWQNYVGFGAKIVVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLSSPMQEDSYNLTTSICLMLFDSVLYAVMTWYIEAVFPGQYGIPRPWYFPFTKSYW---CGEK 873          
BLAST of SMED30024029 vs. Ensembl Zebrafish
Match: abca1a (ATP-binding cassette, sub-family A (ABC1), member 1A [Source:ZFIN;Acc:ZDB-GENE-031006-12])

HSP 1 Score: 108.997 bits (271), Expect = 1.088e-27
Identity = 50/135 (37.04%), Postives = 83/135 (61.48%), Query Frame = -1
Query:   86 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKS 490
              F +A++A+  GGI+YF  YLP+++ V  Q+ +        +LL+ V+      + A +E+   GIQ+SNL  S + + ++ +   + +M  DSV+Y ++ WYIE VFPGQ+G+ +PW FPFT++YW   CG+ 
Sbjct:  742 TLFSRANLAAACGGIIYFTLYLPYVLCVAWQNYVGFGAKIVVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLSSPMQEDSYNLTTSICLMLFDSVLYAVMTWYIEAVFPGQYGIPRPWYFPFTKSYW---CGEK 873          
BLAST of SMED30024029 vs. Ensembl Zebrafish
Match: abca12 (ATP-binding cassette, sub-family A (ABC1), member 12 [Source:ZFIN;Acc:ZDB-GENE-030131-9790])

HSP 1 Score: 101.679 bits (252), Expect = 3.836e-25
Identity = 46/137 (33.58%), Postives = 86/137 (62.77%), Query Frame = -1
Query:   86 FFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWI---SICGKS 487
            FFDK ++A +SG ++Y + + PF++ ++L+D+++  +  A +L +    S +  +IA +E+  +GIQ+SN++ S +       G    ++ IDS++Y +I  YI  VFPG++G++ PW FP T+++W    S C K+
Sbjct:  382 FFDKTNIAGLSGSLIYVISFFPFIVLIHLEDNLSFSVKSALSLFSPTCFSYASQYIARYEKQEEGIQWSNMYISPLAGDTSSFGWLCWLLLIDSLVYFIIGIYIRMVFPGKYGIAVPWYFPVTKSFWTDMFSCCSKT 518          
BLAST of SMED30024029 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 105.531 bits (262), Expect = 2.577e-26
Identity = 50/146 (34.25%), Postives = 85/146 (58.22%), Query Frame = -1
Query:   53 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNP 490
              F +A++A+  GGI+YF  YLP+++ V  QD +   +   A+ L+ V+        A  E+   G+Q+ NL +S + +  + +     MM  D+++Y ++ WYIE VFPGQ+G+ +PW FPFT++YW   CG    +E + ++ P
Sbjct:  691 TIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGYTLKIFASFLSPVAFGFGCEVFALLEEQGVGVQWDNLLESPLEENGYNITTSGFMMLFDTLLYGIMTWYIEAVFPGQYGIPRPWYFPFTKSYW---CG----EECKEYNQP 829          
BLAST of SMED30024029 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 105.531 bits (262), Expect = 2.679e-26
Identity = 50/146 (34.25%), Postives = 85/146 (58.22%), Query Frame = -1
Query:   53 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNP 490
              F +A++A+  GGI+YF  YLP+++ V  QD +   +   A+ L+ V+        A  E+   G+Q+ NL +S + +  + +     MM  D+++Y ++ WYIE VFPGQ+G+ +PW FPFT++YW   CG    +E + ++ P
Sbjct:  708 TIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGYTLKIFASFLSPVAFGFGCEVFALLEEQGVGVQWDNLLESPLEENGYNITTSGFMMLFDTLLYGIMTWYIEAVFPGQYGIPRPWYFPFTKSYW---CG----EECKEYNQP 846          
BLAST of SMED30024029 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 105.145 bits (261), Expect = 2.710e-26
Identity = 50/146 (34.25%), Postives = 85/146 (58.22%), Query Frame = -1
Query:   53 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNP 490
              F +A++A+  GGI+YF  YLP+++ V  QD +   +   A+ L+ V+        A  E+   G+Q+ NL +S + +  + +     MM  D+++Y ++ WYIE VFPGQ+G+ +PW FPFT++YW   CG    +E + ++ P
Sbjct:  740 TIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGYTLKIFASFLSPVAFGFGCEVFALLEEQGVGVQWDNLLESPLEENGYNITTSGFMMLFDTLLYGIMTWYIEAVFPGQYGIPRPWYFPFTKSYW---CG----EECKEYNQP 878          
BLAST of SMED30024029 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 105.145 bits (261), Expect = 2.711e-26
Identity = 50/146 (34.25%), Postives = 85/146 (58.22%), Query Frame = -1
Query:   53 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNP 490
              F +A++A+  GGI+YF  YLP+++ V  QD +   +   A+ L+ V+        A  E+   G+Q+ NL +S + +  + +     MM  D+++Y ++ WYIE VFPGQ+G+ +PW FPFT++YW   CG    +E + ++ P
Sbjct:  742 TIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGYTLKIFASFLSPVAFGFGCEVFALLEEQGVGVQWDNLLESPLEENGYNITTSGFMMLFDTLLYGIMTWYIEAVFPGQYGIPRPWYFPFTKSYW---CG----EECKEYNQP 880          
BLAST of SMED30024029 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 105.145 bits (261), Expect = 2.763e-26
Identity = 50/146 (34.25%), Postives = 85/146 (58.22%), Query Frame = -1
Query:   53 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNP 490
              F +A++A+  GGI+YF  YLP+++ V  QD +   +   A+ L+ V+        A  E+   G+Q+ NL +S + +  + +     MM  D+++Y ++ WYIE VFPGQ+G+ +PW FPFT++YW   CG    +E + ++ P
Sbjct:  738 TIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGYTLKIFASFLSPVAFGFGCEVFALLEEQGVGVQWDNLLESPLEENGYNITTSGFMMLFDTLLYGIMTWYIEAVFPGQYGIPRPWYFPFTKSYW---CG----EECKEYNQP 876          
BLAST of SMED30024029 vs. Ensembl Mouse
Match: Abca1 (ATP-binding cassette, sub-family A (ABC1), member 1 [Source:MGI Symbol;Acc:MGI:99607])

HSP 1 Score: 107.071 bits (266), Expect = 4.723e-27
Identity = 51/146 (34.93%), Postives = 87/146 (59.59%), Query Frame = -1
Query:   53 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNP 490
              F +A++A+  GGI+YF  YLP+++ V  QD +   +   A+LL+ V+      + A +E+   G+Q+ NLF+S + +  F +   + MM  D+ +Y ++ WYIE VFPGQ+G+ +PW FP T++YW         +E++  S+P
Sbjct:  738 TLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFSIKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTAVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCTKSYWFG-------EEIDEKSHP 876          
BLAST of SMED30024029 vs. Ensembl Mouse
Match: Abca3 (ATP-binding cassette, sub-family A (ABC1), member 3 [Source:MGI Symbol;Acc:MGI:1351617])

HSP 1 Score: 105.531 bits (262), Expect = 1.634e-26
Identity = 52/147 (35.37%), Postives = 83/147 (56.46%), Query Frame = -1
Query:   53 FFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICG--KSNLDEMESFSNP 487
            FF KA++A+  GG LYF  Y P+       + MT+     + LL+ V+++     I  +E    GIQ+ +L +   +D NF  G  + M+ +DS +Y L+ WY+E VFPGQFG+ +PW+F    +YW   CG  ++ + + E  S+P
Sbjct:  367 FFSKANIAAAVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLSCLLSNVAMAMGAQLIGKFEAKGTGIQWRDLLNPVNVDDNFCFGQVLGMLLLDSALYGLVTWYVEAVFPGQFGVPQPWHFFLMPSYW---CGNPRTVVGKEEEGSDP 510          
BLAST of SMED30024029 vs. Ensembl Mouse
Match: Abca3 (ATP-binding cassette, sub-family A (ABC1), member 3 [Source:MGI Symbol;Acc:MGI:1351617])

HSP 1 Score: 105.531 bits (262), Expect = 1.634e-26
Identity = 52/147 (35.37%), Postives = 83/147 (56.46%), Query Frame = -1
Query:   53 FFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICG--KSNLDEMESFSNP 487
            FF KA++A+  GG LYF  Y P+       + MT+     + LL+ V+++     I  +E    GIQ+ +L +   +D NF  G  + M+ +DS +Y L+ WY+E VFPGQFG+ +PW+F    +YW   CG  ++ + + E  S+P
Sbjct:  367 FFSKANIAAAVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLSCLLSNVAMAMGAQLIGKFEAKGTGIQWRDLLNPVNVDDNFCFGQVLGMLLLDSALYGLVTWYVEAVFPGQFGVPQPWHFFLMPSYW---CGNPRTVVGKEEEGSDP 510          
BLAST of SMED30024029 vs. Ensembl Mouse
Match: Abca3 (ATP-binding cassette, sub-family A (ABC1), member 3 [Source:MGI Symbol;Acc:MGI:1351617])

HSP 1 Score: 105.145 bits (261), Expect = 2.224e-26
Identity = 52/147 (35.37%), Postives = 83/147 (56.46%), Query Frame = -1
Query:   53 FFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICG--KSNLDEMESFSNP 487
            FF KA++A+  GG LYF  Y P+       + MT+     + LL+ V+++     I  +E    GIQ+ +L +   +D NF  G  + M+ +DS +Y L+ WY+E VFPGQFG+ +PW+F    +YW   CG  ++ + + E  S+P
Sbjct:  367 FFSKANIAAAVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLSCLLSNVAMAMGAQLIGKFEAKGTGIQWRDLLNPVNVDDNFCFGQVLGMLLLDSALYGLVTWYVEAVFPGQFGVPQPWHFFLMPSYW---CGNPRTVVGKEEEGSDP 510          
BLAST of SMED30024029 vs. Ensembl Mouse
Match: Abca4 (ATP-binding cassette, sub-family A (ABC1), member 4 [Source:MGI Symbol;Acc:MGI:109424])

HSP 1 Score: 101.679 bits (252), Expect = 4.193e-25
Identity = 53/168 (31.55%), Postives = 87/168 (51.79%), Query Frame = -1
Query:    2 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSN-----LDEMESFSNPLNEPIPNESLNERGFEH 490
              F KAS+A+   G++YF  YLP ++    QD MT  +    +LL+ V+      ++  +E+   G+Q+SN+  S +    F     M MM +D+ +Y L+AWY++ VFPG +G   PW F    +YW+   G S      L++ E  +  + +P   E +N+  FE 
Sbjct:  753 TLFSKASLAAACSGVIYFTLYLPHVLCFAWQDRMTADLKTTVSLLSSVAFGFGTEYLVRFEEQGLGLQWSNIGKSPLEGDEFSFLLSMKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLGGEGCSTREERALEKTEPLTEEMEDPEHPEGMNDSFFER 920          
BLAST of SMED30024029 vs. UniProt/SwissProt
Match: sp|P41233|ABCA1_MOUSE (Phospholipid-transporting ATPase ABCA1 OS=Mus musculus OX=10090 GN=Abca1 PE=1 SV=4)

HSP 1 Score: 107.071 bits (266), Expect = 3.304e-26
Identity = 51/146 (34.93%), Postives = 87/146 (59.59%), Query Frame = -1
Query:   53 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNP 490
              F +A++A+  GGI+YF  YLP+++ V  QD +   +   A+LL+ V+      + A +E+   G+Q+ NLF+S + +  F +   + MM  D+ +Y ++ WYIE VFPGQ+G+ +PW FP T++YW         +E++  S+P
Sbjct:  738 TLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFSIKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTAVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCTKSYWFG-------EEIDEKSHP 876          
BLAST of SMED30024029 vs. UniProt/SwissProt
Match: sp|O95477|ABCA1_HUMAN (Phospholipid-transporting ATPase ABCA1 OS=Homo sapiens OX=9606 GN=ABCA1 PE=1 SV=3)

HSP 1 Score: 107.071 bits (266), Expect = 3.857e-26
Identity = 48/128 (37.50%), Postives = 80/128 (62.50%), Query Frame = -1
Query:  107 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 490
              F +A++A+  GGI+YF  YLP+++ V  QD +   +   A+LL+ V+      + A +E+   G+Q+ NLF+S + +  F +   + MM  D+ +Y ++ WYIE VFPGQ+G+ +PW FP T++YW
Sbjct:  738 TLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPWYFPCTKSYW 865          
BLAST of SMED30024029 vs. UniProt/SwissProt
Match: sp|Q8R420|ABCA3_MOUSE (ATP-binding cassette sub-family A member 3 OS=Mus musculus OX=10090 GN=Abca3 PE=1 SV=3)

HSP 1 Score: 105.531 bits (262), Expect = 1.143e-25
Identity = 52/147 (35.37%), Postives = 83/147 (56.46%), Query Frame = -1
Query:   53 FFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICG--KSNLDEMESFSNP 487
            FF KA++A+  GG LYF  Y P+       + MT+     + LL+ V+++     I  +E    GIQ+ +L +   +D NF  G  + M+ +DS +Y L+ WY+E VFPGQFG+ +PW+F    +YW   CG  ++ + + E  S+P
Sbjct:  367 FFSKANIAAAVGGFLYFFTYTPYFFVAPRYNWMTLSQKLLSCLLSNVAMAMGAQLIGKFEAKGTGIQWRDLLNPVNVDDNFCFGQVLGMLLLDSALYGLVTWYVEAVFPGQFGVPQPWHFFLMPSYW---CGNPRTVVGKEEEGSDP 510          
BLAST of SMED30024029 vs. UniProt/SwissProt
Match: sp|Q7TNJ2|ABCA7_RAT (ATP-binding cassette sub-family A member 7 OS=Rattus norvegicus OX=10116 GN=Abca7 PE=1 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 1.594e-25
Identity = 49/132 (37.12%), Postives = 77/132 (58.33%), Query Frame = -1
Query:   92 FFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICG 487
            FF +A++A+  GG+ YF  YLP+++ V  ++ + +    A +LL+ V+       +A  E+  DG Q+ NL      D+ F +      + +D+VIY L  WY+E V PGQ+G+ +PWNFPF R+YW   CG
Sbjct:  647 FFSRANLAAACGGLAYFALYLPYVLCVAWRERLPLGGLLAVSLLSPVAFGFGCESLALLEEQGDGAQWHNLGTGPAEDV-FSLAQVSAFLLLDAVIYGLALWYLEAVCPGQYGIPEPWNFPFRRSYW---CG 774          
BLAST of SMED30024029 vs. UniProt/SwissProt
Match: sp|Q99758|ABCA3_HUMAN (ATP-binding cassette sub-family A member 3 OS=Homo sapiens OX=9606 GN=ABCA3 PE=1 SV=2)

HSP 1 Score: 104.76 bits (260), Expect = 2.082e-25
Identity = 50/133 (37.59%), Postives = 76/133 (57.14%), Query Frame = -1
Query:   89 FFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGK 487
            FF KA++A+  GG LYF  Y+P+       + MT+     + LL+ V+++     I  +E    GIQ+ +L     +D +F  G  + M+ +DSV+Y L+ WY+E VFPGQFG+ +PW F    +YW   CGK
Sbjct:  367 FFSKANMAAAFGGFLYFFTYIPYFFVAPRYNWMTLSQKLCSCLLSNVAMAMGAQLIGKFEAKGMGIQWRDLLSPVNVDDDFCFGQVLGMLLLDSVLYGLVTWYMEAVFPGQFGVPQPWYFFIMPSYW---CGK 496          
BLAST of SMED30024029 vs. TrEMBL
Match: A0A1I8G995 (ABC transporter domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 3.120e-32
Identity = 56/135 (41.48%), Postives = 84/135 (62.22%), Query Frame = -1
Query:   86 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKS 490
            +FF  +SVA+   G++YF+ Y+P+ +  +  DSMT P Y  + L+ Q++      FI  WE ++ G+Q  N +DS +    F     +VMMWIDS I +L+ WY+E VFPG +G+ KPW FPF+ +YW   CG+S
Sbjct: 1665 IFFSNSSVAAAFAGVIYFLGYVPYSVVDSFSDSMTRPQYLLSCLIPQLAFGVGCKFIGSWELASVGLQHKNFYDSPLATSEFTFNQVVVMMWIDSGILMLLTWYLEKVFPGAYGVPKPWYFPFSPSYW---CGQS 1796          
BLAST of SMED30024029 vs. TrEMBL
Match: A0A1I8GAM3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 5.856e-31
Identity = 54/134 (40.30%), Postives = 82/134 (61.19%), Query Frame = -1
Query:   89 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGK 490
            +FF  +SVA+    ++YF  YLPF +     +SMT   Y  + L+ Q++      FI+ WE ++ G+Q+ N FDS   +     G  ++M+WIDS I++L+ WY+E VFPG+FG+ KPW FPF  ++W   CGK
Sbjct: 3309 IFFSNSSVAAAFARVIYFAGYLPFNLLETFGNSMTRTHYILSCLIPQLAFGVGCKFISNWELASVGLQYDNFFDSPAANGELSFGLVILMLWIDSAIFMLLTWYLEKVFPGEFGVPKPWFFPFQPSFW---CGK 3439          
BLAST of SMED30024029 vs. TrEMBL
Match: A0A1I8FY36 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 9.235e-30
Identity = 56/136 (41.18%), Postives = 84/136 (61.76%), Query Frame = -1
Query:   83 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSN 490
            +FF  +SVA+   G++YF+ Y+P+ +  +  DSMT P Y  + L+ Q++      FI  WE ++ G+Q  N +DS +    F     +VMMWIDS I +L+ WY+E VFPG +G+ KPW FPF+ +YW   CG+S 
Sbjct:  874 IFFSNSSVAAAFAGVIYFLGYVPYSVVDSFSDSMTRPQYLLSCLIPQLAFGVGCKFIGSWELASVGLQHKNFYDSPLATSEFTFNQVVVMMWIDSGILMLLTWYLEKVFPGAYGVPKPWYFPFSPSYW---CGQSK 1006          
BLAST of SMED30024029 vs. TrEMBL
Match: A0A1I8GCG0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 9.770e-30
Identity = 56/136 (41.18%), Postives = 84/136 (61.76%), Query Frame = -1
Query:   83 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSN 490
            +FF  +SVA+   G++YF+ Y+P+ +  +  DSMT P Y  + L+ Q++      FI  WE ++ G+Q  N +DS +    F     +VMMWIDS I +L+ WY+E VFPG +G+ KPW FPF+ +YW   CG+S 
Sbjct:  873 IFFSNSSVAAAFAGVIYFLGYVPYSVVDSFSDSMTRPQYLLSCLIPQLAFGVGCKFIGSWELASVGLQHKNFYDSPLATSEFTFNQVVVMMWIDSGILMLLTWYLEKVFPGAYGVPKPWYFPFSPSYW---CGQSK 1005          
BLAST of SMED30024029 vs. TrEMBL
Match: A0A267E4U2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028120g1 PE=4 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 9.777e-30
Identity = 56/136 (41.18%), Postives = 84/136 (61.76%), Query Frame = -1
Query:   83 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSN 490
            +FF  +SVA+   G++YF+ Y+P+ +  +  DSMT P Y  + L+ Q++      FI  WE ++ G+Q  N +DS +    F     +VMMWIDS I +L+ WY+E VFPG +G+ KPW FPF+ +YW   CG+S 
Sbjct:  760 IFFSNSSVAAAFAGVIYFLGYVPYSVVDSFSDSMTRPQYLLSCLIPQLAFGVGCKFIGSWELASVGLQHKNFYDSPLATSEFTFNQVVVMMWIDSGILMLLTWYLEKVFPGAYGVPKPWYFPFSPSYW---CGQSK 892          
BLAST of SMED30024029 vs. Ensembl Cavefish
Match: ENSAMXT00000016919.2 (pep primary_assembly:Astyanax_mexicanus-2.0:8:9912642:9956080:1 gene:ENSAMXG00000016432.2 transcript:ENSAMXT00000016919.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 115.161 bits (287), Expect = 5.210e-30
Identity = 50/126 (39.68%), Postives = 84/126 (66.67%), Query Frame = -1
Query:  107 FDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 484
            F +A++A+  GGI+YF  YLP+++ V  QD + +P    A+LL+ V+      + A +E+   GIQ+ NLF S +   ++ +   +++M++D+ IY ++ WYIE VFPGQ+G+ +PW FPFT++YW
Sbjct:  635 FARANLAAACGGIIYFTLYLPYVLCVAWQDYIGLPAKVIASLLSPVAFGFGCEYFALFEEQGVGIQWKNLFSSPMEKDDYSLTTSIIIMYVDAFIYGVMTWYIEAVFPGQYGIPRPWYFPFTKSYW 760          
BLAST of SMED30024029 vs. Ensembl Cavefish
Match: ENSAMXT00000022236.2 (pep primary_assembly:Astyanax_mexicanus-2.0:21:13397857:13560117:1 gene:ENSAMXG00000021540.2 transcript:ENSAMXT00000022236.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 112.079 bits (279), Expect = 7.120e-29
Identity = 57/155 (36.77%), Postives = 92/155 (59.35%), Query Frame = -1
Query:   32 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWIS--ICGKSNLDEMESFSNPLNEPIPN 490
            VFF +A++A+  GG++YF+ YLP ++    +D +T     A +LL+ V+        A +E+   GIQ+SN+F S+  D  +     +VMM +D+++Y ++ WYIE VFPGQ+G+ KPW FPFT +YW    +   +  D ++  S  L +P P 
Sbjct:  502 VFFSRANLAAACGGLIYFLLYLPHVLCQAWRDVITFRAKLATSLLSCVAFGYGCENFARYEEQGVGIQWSNIFVSSQEDDPYSFFVSIVMMLVDTLMYWILTWYIENVFPGQYGIPKPWYFPFTSSYWCGTPVGSDTEPDALDGSSRYLEKPPPG 656          
BLAST of SMED30024029 vs. Ensembl Cavefish
Match: abca4a (retinal-specific ATP-binding cassette transporter-like [Source:NCBI gene;Acc:103024609])

HSP 1 Score: 110.538 bits (275), Expect = 2.271e-28
Identity = 54/159 (33.96%), Postives = 96/159 (60.38%), Query Frame = -1
Query:   14 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNEPIPNESLNER 490
            VFF+KA++A+   GILYF FYLP L     QD +T  M   A+L++QV+      +++ +E+   G+Q+ N+  S +    F     ++MM +D+V+Y ++AWY+++VFPGQ+G+ +P+ FP   +YW+++            +NP  + +P +S+ +R
Sbjct:  753 VFFNKANLAAACSGILYFSFYLPHLACFTWQDRITKDMKIMASLMSQVAFGFGTEYLSRYEEQGLGLQWDNIHTSPLEGDEFSFHTSIIMMLLDTVLYAVLAWYLDSVFPGQYGIGRPFYFPIQPSYWLNL------------TNP-TKAVPEKSVVKR 898          
BLAST of SMED30024029 vs. Ensembl Cavefish
Match: abca4a (retinal-specific ATP-binding cassette transporter-like [Source:NCBI gene;Acc:103024609])

HSP 1 Score: 110.538 bits (275), Expect = 2.408e-28
Identity = 54/159 (33.96%), Postives = 96/159 (60.38%), Query Frame = -1
Query:   14 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNEPIPNESLNER 490
            VFF+KA++A+   GILYF FYLP L     QD +T  M   A+L++QV+      +++ +E+   G+Q+ N+  S +    F     ++MM +D+V+Y ++AWY+++VFPGQ+G+ +P+ FP   +YW+++            +NP  + +P +S+ +R
Sbjct:  753 VFFNKANLAAACSGILYFSFYLPHLACFTWQDRITKDMKIMASLMSQVAFGFGTEYLSRYEEQGLGLQWDNIHTSPLEGDEFSFHTSIIMMLLDTVLYAVLAWYLDSVFPGQYGIGRPFYFPIQPSYWLNL------------TNP-TKAVPEKSVVKR 898          
BLAST of SMED30024029 vs. Ensembl Cavefish
Match: abca1a (ATP-binding cassette sub-family A member 1-like [Source:NCBI gene;Acc:103028164])

HSP 1 Score: 107.842 bits (268), Expect = 2.424e-27
Identity = 49/135 (36.30%), Postives = 83/135 (61.48%), Query Frame = -1
Query:   86 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKS 490
              F +A++A+  GGI+YF  YLP+++ V  QD +        +LL+ V+      + A +E+   GIQ+SNL  S + + ++ +   + +M  D+++Y ++ WYIE VFPGQ+G+ +PW FPFT++YW   CG+ 
Sbjct:  741 TIFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFGAKVVVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLSSPLEEDSYSLTTSISLMLFDALLYAVMTWYIEAVFPGQYGIPRPWYFPFTKSYW---CGEK 872          
BLAST of SMED30024029 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002495.1 (pep scaffold:Pmarinus_7.0:GL480265:53:27909:1 gene:ENSPMAG00000002218.1 transcript:ENSPMAT00000002495.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 102.834 bits (255), Expect = 2.149e-26
Identity = 51/146 (34.93%), Postives = 85/146 (58.22%), Query Frame = -1
Query:   53 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNP 490
             FF +A++A+ +GGI+YF FYLP+++ V  Q+ +T  +  + ++ + V+ S    F + +E+   G+Q+ N+F S +   ++     + MM  D+ +Y L+  YIE VFPGQ+G+ KPW FP TR YW     +  L E  +   P
Sbjct:  195 TFFSRANLAAATGGIVYFSFYLPYVLCVAWQNQITYSVKISTSIFSTVAFSFGSEFFSLYEEQGVGMQWENVFSSPVEGEDYTFISSIFMMLFDAFVYGLLTVYIENVFPGQYGVPKPWYFPCTRAYWRGDTMEKELYETIAQKQP 340          
BLAST of SMED30024029 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004117.1 (pep scaffold:Pmarinus_7.0:GL489716:190:6182:-1 gene:ENSPMAG00000003765.1 transcript:ENSPMAT00000004117.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.1149 bits (209), Expect = 2.619e-20
Identity = 48/159 (30.19%), Postives = 86/159 (54.09%), Query Frame = -1
Query:   29 VFFDKASVASVSGGILYFVFYLPFLIFVNLQ-----DSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNEPIPNE 490
            V + KA +A+  GGI+YF+ Y+P++ +V ++     D +T      A+L++  +      + A +E +  GIQ+     S +   +F +   ++M+ +DSV+Y ++ WYIE V PG +GL +PW FP  R+YW+   G+++  E   +     E  P  
Sbjct:  188 VLYSKARMAAACGGIMYFLSYVPYM-YVAIREEVAHDKITAFEKCIASLMSTTAFGLGAKYFALYEVAGVGIQWHTFRQSPVEGDDFNLSLALLMLLLDSVVYGVLTWYIEAVHPGTYGLPRPWYFPLQRSYWLG-SGRADAWEWSGYEARGMEKEPTH 344          
BLAST of SMED30024029 vs. Ensembl Sea Lamprey
Match: abca12 (ATP-binding cassette, sub-family A (ABC1), member 12 [Source:ZFIN;Acc:ZDB-GENE-030131-9790])

HSP 1 Score: 66.2402 bits (160), Expect = 1.238e-13
Identity = 38/130 (29.23%), Postives = 66/130 (50.77%), Query Frame = -1
Query:  116 FDKASVASVSGGILYFVFYLPFLIFVNLQDSMT--VPMYYAAALLTQVSLSNSINFIAYWEQST-----DGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTR 484
            F   +VAS++   +Y + + PFL   +L   +T          LL+  + S + N I   +  T       +Q+SN++ S +   +    +   M+ ID+ IY ++ WYI  V+PG +GL++P+ F FTR
Sbjct:  191 FTHTNVASLTACFIYLLSFFPFLALSSLTLKLTRWQKSLIVRCLLSPTAFSYATNLIT--QHCTCIPMRALVQWSNMYHSPLFGDDVSFAYLCWMLIIDTAIYFILGWYIRNVYPGTYGLARPFYFLFTR 318          
BLAST of SMED30024029 vs. Ensembl Nematostella
Match: EDO46878 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNL9])

HSP 1 Score: 105.916 bits (263), Expect = 3.237e-27
Identity = 50/128 (39.06%), Postives = 78/128 (60.94%), Query Frame = -1
Query:  107 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 490
            VFF +A+V++  GGI++FV YLP+ +    +  M      AA L +  +   + N++A +E+   G Q++NL+ S I    F +G+ M MM ID V+Y L  +YIE V PGQ+G+ +PW FP  ++YW
Sbjct:  206 VFFSRANVSAACGGIIFFVTYLPYTMVRWFEAFMNSSQIAAACLSSTTAFGVACNYLARYEEQGVGAQWNNLYASPIAGDEFSLGYAMGMMMIDGVLYALATFYIEAVMPGQYGIPRPWYFPLQKSYW 333          
BLAST of SMED30024029 vs. Ensembl Nematostella
Match: EDO38879 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBQ0])

HSP 1 Score: 90.8929 bits (224), Expect = 6.122e-22
Identity = 44/133 (33.08%), Postives = 77/133 (57.89%), Query Frame = -1
Query:  107 VFFDKASVASVSGGILYFVFYLPFLIFVNLQD-----SMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 490
             FF KA +A+  GGI+YF+ Y+PF +FV++++     ++      A +LL+  +      + A +E+  +G+Q+SN+  S I   +F +   +  +  D+ +Y+++ WYIE V PG +GL +PW FP    YW
Sbjct:  426 AFFSKAKLAAACGGIIYFLTYMPF-VFVSIREGAAHATIESSEKMAISLLSTSAFGLGARYFALYEEQGEGVQWSNIGKSPIRGDDFNLLKVLYFLVFDTFLYVILVWYIEAVHPGSYGLPRPWYFPIQPTYW 557          
BLAST of SMED30024029 vs. Ensembl Nematostella
Match: EDO48951 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI12])

HSP 1 Score: 89.3521 bits (220), Expect = 2.123e-21
Identity = 54/161 (33.54%), Postives = 85/161 (52.80%), Query Frame = -1
Query:   29 VFFDKASVASVSGGILYFVFYLPFLIFVNLQ--DSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMES-----FSNPLNEPIPNE 490
            VFF   +++ + G +L++   LP+ +    +  D+++     +  LL    L      IA  E    G  FSNL  S   D +F +   + MM I S++YL++ WYI TVFPGQ+G+ KP+ FPF ++YW   CG S+ D +E+      +NP  E  P +
Sbjct:  337 VFFSNPTLSMLFGSVLWYAALLPYQLLAQNENYDTLSQSAKASMCLLPNTCLGIGATLIARLEGFKTGASFSNLASSPSADDHFSLAWVLGMMIISSLVYLILTWYISTVFPGQYGIPKPFYFPFMKSYW---CGFSHDDVVEAGLERVKNNPAIEDEPTD 494          
BLAST of SMED30024029 vs. Ensembl Medaka
Match: abca1a (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163147])

HSP 1 Score: 109.383 bits (272), Expect = 5.384e-28
Identity = 51/143 (35.66%), Postives = 86/143 (60.14%), Query Frame = -1
Query:   62 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESF 490
              F +A++A+  GGI+YF  YLP+++ V  QD +        +LL+ V+      + A +E+   GIQ+SNL  S + + ++ +   + +M  D+V+Y ++ WYIE+VFPGQ+G+ +PW FPFT++YW   CG+     M + 
Sbjct:  743 TLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFGAKVLVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLASPLEEDSYNLTTSICLMLFDAVLYGIMTWYIESVFPGQYGIPRPWYFPFTKSYW---CGEKENKNMSAL 882          
BLAST of SMED30024029 vs. Ensembl Medaka
Match: abca1a (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163147])

HSP 1 Score: 109.383 bits (272), Expect = 5.813e-28
Identity = 51/143 (35.66%), Postives = 86/143 (60.14%), Query Frame = -1
Query:   62 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESF 490
              F +A++A+  GGI+YF  YLP+++ V  QD +        +LL+ V+      + A +E+   GIQ+SNL  S + + ++ +   + +M  D+V+Y ++ WYIE+VFPGQ+G+ +PW FPFT++YW   CG+     M + 
Sbjct:  730 TLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFGAKVLVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLASPLEEDSYNLTTSICLMLFDAVLYGIMTWYIESVFPGQYGIPRPWYFPFTKSYW---CGEKENKNMSAL 869          
BLAST of SMED30024029 vs. Ensembl Medaka
Match: abca1a (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163147])

HSP 1 Score: 109.383 bits (272), Expect = 6.104e-28
Identity = 51/143 (35.66%), Postives = 86/143 (60.14%), Query Frame = -1
Query:   62 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESF 490
              F +A++A+  GGI+YF  YLP+++ V  QD +        +LL+ V+      + A +E+   GIQ+SNL  S + + ++ +   + +M  D+V+Y ++ WYIE+VFPGQ+G+ +PW FPFT++YW   CG+     M + 
Sbjct:  743 TLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFGAKVLVSLLSPVAFGFGCEYFALFEEQGVGIQWSNLLASPLEEDSYNLTTSICLMLFDAVLYGIMTWYIESVFPGQYGIPRPWYFPFTKSYW---CGEKENKNMSAL 882          
BLAST of SMED30024029 vs. Ensembl Medaka
Match: ENSORLT00000025407.2 (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163308])

HSP 1 Score: 103.99 bits (258), Expect = 4.780e-26
Identity = 47/116 (40.52%), Postives = 75/116 (64.66%), Query Frame = -1
Query:  107 GGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYW 454
            GGI+YF  YLP+++ V  QD +       A+LL+ V+      + A +E+   GIQ+SNL  S + + +F +   +++M+ DS +Y ++ WYIE VFPGQ+G+ +PW FPFT++YW
Sbjct:  756 GGIIYFTLYLPYVLCVAWQDYIGYGAKVMASLLSPVAFGFGCEYFALFEEQGVGIQWSNLLSSPLQEDDFSLRTTILVMYFDSFLYGVLTWYIEAVFPGQYGIPRPWYFPFTKSYW 871          
BLAST of SMED30024029 vs. Ensembl Medaka
Match: abca3b (ATP binding cassette subfamily A member 3 [Source:NCBI gene;Acc:101174998])

HSP 1 Score: 102.064 bits (253), Expect = 2.504e-25
Identity = 49/130 (37.69%), Postives = 79/130 (60.77%), Query Frame = -1
Query:  101 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWIS 490
             FF +A+VA+ +GG +YF+ YLP+L      D ++     +A L++ V+++     I  +E    GIQ+SNLFDS  +D +F +   + ++  DSV+Y L+AWY+E VFPG++G+  P  F    +YW S
Sbjct:  360 AFFSRANVAAAAGGFIYFLSYLPYLFLWPRYDLLSHGQKVSACLISNVAMAMGAQLIGMFEGKGTGIQWSNLFDSVTVDDDFSLAQVLCLLLFDSVLYGLVAWYVEAVFPGEYGVPLPSYFFLLPSYWCS 489          
BLAST of SMED30024029 vs. Planmine SMEST
Match: SMESG000068605.1 (SMESG000068605.1)

HSP 1 Score: 333.569 bits (854), Expect = 2.439e-106
Identity = 159/163 (97.55%), Postives = 160/163 (98.16%), Query Frame = -1
Query:    2 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNEPIPNESLNERGFEH 490
            VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWY+ETVFPGQFGLSKPWNFPFTRNYW SICGKSNLDE ESFSN LNEPIPNESLNERGFEH
Sbjct:  539 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYVETVFPGQFGLSKPWNFPFTRNYWNSICGKSNLDETESFSNSLNEPIPNESLNERGFEH 701          
BLAST of SMED30024029 vs. Planmine SMEST
Match: SMESG000032891.1 (SMESG000032891.1)

HSP 1 Score: 214.542 bits (545), Expect = 8.574e-65
Identity = 104/167 (62.28%), Postives = 128/167 (76.65%), Query Frame = -1
Query:    5 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNE---PIP--NESLNERGFE 490
            V FDKA+VASV+GGI+YF+ YLPF +F+NL D +T  MYY   LLTQV+  NSINFIA+WEQSTDG+QFSNLFDS +++LN GVGHCMVMMW+DSVIYLLIAWY+E+VFPGQ+G+ KPW F FTR+YW   C  S  D++    N  +    PIP  NE + + GFE
Sbjct:  501 VLFDKANVASVAGGIIYFISYLPFYVFLNLPDDVTDSMYYGVGLLTQVAFCNSINFIAFWEQSTDGVQFSNLFDSTVVNLNVGVGHCMVMMWVDSVIYLLIAWYVESVFPGQYGVGKPWYFLFTRHYW---CQNSASDKITLIDNHYSYESLPIPNINEGILKHGFE 664          
BLAST of SMED30024029 vs. Planmine SMEST
Match: SMESG000032861.1 (SMESG000032861.1)

HSP 1 Score: 213.001 bits (541), Expect = 3.108e-64
Identity = 98/164 (59.76%), Postives = 128/164 (78.05%), Query Frame = -1
Query:    5 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNEPIP--NESLNERGFE 490
            VFFDKA+VA+V+GGI+YF+ YLPF +F+ + D +T  MYY   LLTQV+ SNSINFIA+WEQSTDG+QFSNLFDS +++LN GVGHCMVMMW+DSVIYLLIAWY+E+VFPGQ+G+ KPW F FT++YW        +  ++++    + PIP  NE + + GFE
Sbjct:  511 VFFDKANVAAVAGGIIYFISYLPFYVFITIPDDVTDSMYYGVGLLTQVAFSNSINFIAFWEQSTDGVQFSNLFDSTVVNLNVGVGHCMVMMWVDSVIYLLIAWYVESVFPGQYGVGKPWYFLFTQHYWCQNSASYKITPIDNYYPYESSPIPNINEGILKHGFE 674          
BLAST of SMED30024029 vs. Planmine SMEST
Match: SMESG000032896.1 (SMESG000032896.1)

HSP 1 Score: 211.075 bits (536), Expect = 1.353e-63
Identity = 101/167 (60.48%), Postives = 127/167 (76.05%), Query Frame = -1
Query:    5 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNE---PIP--NESLNERGFE 490
            VFFDKA+VA+V+GGI+Y + YLPF +F+ + D +T  MYY   LLTQV+  NSINFIA+WEQSTDG+QFSNLFDS +++LN GVGHCMVMMW+DSVIYLLIAWY+E+VFPGQ+G+ KPW F FTR+YW   C  S  D++    N  +    PIP  NE + + GFE
Sbjct:  501 VFFDKANVAAVAGGIIYSILYLPFYVFITIPDDVTDSMYYGVGLLTQVAFCNSINFIAFWEQSTDGVQFSNLFDSTVVNLNVGVGHCMVMMWVDSVIYLLIAWYVESVFPGQYGVGKPWYFLFTRHYW---CQNSASDKITLIDNHYSYESLPIPNINEGILKHGFE 664          
BLAST of SMED30024029 vs. Planmine SMEST
Match: SMESG000032896.1 (SMESG000032896.1)

HSP 1 Score: 211.075 bits (536), Expect = 1.448e-63
Identity = 101/167 (60.48%), Postives = 127/167 (76.05%), Query Frame = -1
Query:    5 VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSLSNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLLIAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNE---PIP--NESLNERGFE 490
            VFFDKA+VA+V+GGI+Y + YLPF +F+ + D +T  MYY   LLTQV+  NSINFIA+WEQSTDG+QFSNLFDS +++LN GVGHCMVMMW+DSVIYLLIAWY+E+VFPGQ+G+ KPW F FTR+YW   C  S  D++    N  +    PIP  NE + + GFE
Sbjct:  498 VFFDKANVAAVAGGIIYSILYLPFYVFITIPDDVTDSMYYGVGLLTQVAFCNSINFIAFWEQSTDGVQFSNLFDSTVVNLNVGVGHCMVMMWVDSVIYLLIAWYVESVFPGQYGVGKPWYFLFTRHYW---CQNSASDKITLIDNHYSYESLPIPNINEGILKHGFE 661          
The following BLAST results are available for this feature:
BLAST of SMED30024029 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ABCA18.031e-2737.50ATP binding cassette subfamily A member 1 [Source:... [more]
ABCA34.335e-2637.59ATP binding cassette subfamily A member 3 [Source:... [more]
ABCA72.920e-2535.61ATP binding cassette subfamily A member 7 [Source:... [more]
ABCA44.227e-2532.14ATP binding cassette subfamily A member 4 [Source:... [more]
ABCA121.223e-2232.03ATP binding cassette subfamily A member 12 [Source... [more]
back to top
BLAST of SMED30024029 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
abt-27.249e-1529.46ABC Transporter family [Source:UniProtKB/TrEMBL;A... [more]
abt-27.612e-1529.46ABC Transporter family [Source:UniProtKB/TrEMBL;A... [more]
abt-46.400e-1325.17ABC Transporter family [Source:UniProtKB/TrEMBL;A... [more]
back to top
BLAST of SMED30024029 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ABCA2.501e-2732.70gene:FBgn0031170 transcript:FBtr0306679[more]
ABCA2.548e-2732.70gene:FBgn0031170 transcript:FBtr0332489[more]
ABCA2.624e-2732.70gene:FBgn0031170 transcript:FBtr0332488[more]
CG60526.126e-1530.83gene:FBgn0036747 transcript:FBtr0075195[more]
CG312131.128e-934.45gene:FBgn0051213 transcript:FBtr0335242[more]
back to top
BLAST of SMED30024029 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abca1b5.975e-2840.52ATP-binding cassette, sub-family A (ABC1), member ... [more]
abca1b6.091e-2840.52ATP-binding cassette, sub-family A (ABC1), member ... [more]
abca1a1.088e-2737.04ATP-binding cassette, sub-family A (ABC1), member ... [more]
abca1a1.088e-2737.04ATP-binding cassette, sub-family A (ABC1), member ... [more]
abca123.836e-2533.58ATP-binding cassette, sub-family A (ABC1), member ... [more]
back to top
BLAST of SMED30024029 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ABCA12.577e-2634.25ATP binding cassette subfamily A member 1 [Source:... [more]
ABCA12.679e-2634.25ATP binding cassette subfamily A member 1 [Source:... [more]
ABCA12.710e-2634.25ATP binding cassette subfamily A member 1 [Source:... [more]
ABCA12.711e-2634.25ATP binding cassette subfamily A member 1 [Source:... [more]
ABCA12.763e-2634.25ATP binding cassette subfamily A member 1 [Source:... [more]
back to top
BLAST of SMED30024029 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Abca14.723e-2734.93ATP-binding cassette, sub-family A (ABC1), member ... [more]
Abca31.634e-2635.37ATP-binding cassette, sub-family A (ABC1), member ... [more]
Abca31.634e-2635.37ATP-binding cassette, sub-family A (ABC1), member ... [more]
Abca32.224e-2635.37ATP-binding cassette, sub-family A (ABC1), member ... [more]
Abca44.193e-2531.55ATP-binding cassette, sub-family A (ABC1), member ... [more]
back to top
BLAST of SMED30024029 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P41233|ABCA1_MOUSE3.304e-2634.93Phospholipid-transporting ATPase ABCA1 OS=Mus musc... [more]
sp|O95477|ABCA1_HUMAN3.857e-2637.50Phospholipid-transporting ATPase ABCA1 OS=Homo sap... [more]
sp|Q8R420|ABCA3_MOUSE1.143e-2535.37ATP-binding cassette sub-family A member 3 OS=Mus ... [more]
sp|Q7TNJ2|ABCA7_RAT1.594e-2537.12ATP-binding cassette sub-family A member 7 OS=Ratt... [more]
sp|Q99758|ABCA3_HUMAN2.082e-2537.59ATP-binding cassette sub-family A member 3 OS=Homo... [more]
back to top
BLAST of SMED30024029 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8G9953.120e-3241.48ABC transporter domain-containing protein OS=Macro... [more]
A0A1I8GAM35.856e-3140.30Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8FY369.235e-3041.18Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8GCG09.770e-3041.18Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267E4U29.777e-3041.18Uncharacterized protein OS=Macrostomum lignano OX=... [more]
back to top
BLAST of SMED30024029 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000016919.25.210e-3039.68pep primary_assembly:Astyanax_mexicanus-2.0:8:9912... [more]
ENSAMXT00000022236.27.120e-2936.77pep primary_assembly:Astyanax_mexicanus-2.0:21:133... [more]
abca4a2.271e-2833.96retinal-specific ATP-binding cassette transporter-... [more]
abca4a2.408e-2833.96retinal-specific ATP-binding cassette transporter-... [more]
abca1a2.424e-2736.30ATP-binding cassette sub-family A member 1-like [S... [more]
back to top
BLAST of SMED30024029 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000002495.12.149e-2634.93pep scaffold:Pmarinus_7.0:GL480265:53:27909:1 gene... [more]
ENSPMAT00000004117.12.619e-2030.19pep scaffold:Pmarinus_7.0:GL489716:190:6182:-1 gen... [more]
abca121.238e-1329.23ATP-binding cassette, sub-family A (ABC1), member ... [more]
back to top
BLAST of SMED30024029 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of SMED30024029 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO468783.237e-2739.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO388796.122e-2233.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO489512.123e-2133.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of SMED30024029 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
abca1a5.384e-2835.66ATP-binding cassette sub-family A member 1 [Source... [more]
abca1a5.813e-2835.66ATP-binding cassette sub-family A member 1 [Source... [more]
abca1a6.104e-2835.66ATP-binding cassette sub-family A member 1 [Source... [more]
ENSORLT00000025407.24.780e-2640.52ATP-binding cassette sub-family A member 1 [Source... [more]
abca3b2.504e-2537.69ATP binding cassette subfamily A member 3 [Source:... [more]
back to top
BLAST of SMED30024029 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000068605.12.439e-10697.55SMESG000068605.1[more]
SMESG000032891.18.574e-6562.28SMESG000032891.1[more]
SMESG000032861.13.108e-6459.76SMESG000032861.1[more]
SMESG000032896.11.353e-6360.48SMESG000032896.1[more]
SMESG000032896.11.448e-6360.48SMESG000032896.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024029 ID=SMED30024029|Name=SMED30024029|organism=Schmidtea mediterranea sexual|type=transcript|length=490bp
CGTGTTCAAATCCTCGCTCATTCAGAGATTCGTTTGGAATCGGCTCATTT
AAAGGATTAGAAAACGATTCCATCTCATCCAAGTTGGATTTTCCACAAAT
CGAAATCCAATAGTTACGAGTGAAAGGAAAATTCCACGGTTTCGATAGGC
CAAATTGGCCGGGAAATACAGTTTCAATGTACCAAGCTATTAATAAATAA
ATCACACTATCAATCCACATCATCACCATGCAATGGCCGACTCCAAAATT
CAGATCCATTATTGCACTGTCAAACAGGTTGCTAAATTGTATCCCATCTG
TCGACTGTTCCCAATATGCAATGAAATTAATAGAATTACTCAACGAAACC
TGAGTCAACAATGCCGCAGCGTAATACATCGGCACGGTCATGCTGTCCTG
CAAGTTGACAAATATCAAAAACGGCAAATAAAATACAAAGTAAAGAATTC
CCCCAGAAACAGATGCAACACTTGCTTTATCAAAAAACAC
back to top

protein sequence of SMED30024029-orf-1

>SMED30024029-orf-1 ID=SMED30024029-orf-1|Name=SMED30024029-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=163bp
VFFDKASVASVSGGILYFVFYLPFLIFVNLQDSMTVPMYYAAALLTQVSL
SNSINFIAYWEQSTDGIQFSNLFDSAIMDLNFGVGHCMVMMWIDSVIYLL
IAWYIETVFPGQFGLSKPWNFPFTRNYWISICGKSNLDEMESFSNPLNEP
IPNESLNERGFEH
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR026082ABCA
Vocabulary: molecular function
TermDefinition
GO:0042626ATPase activity, coupled to transmembrane movement of substances
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR026082ABC transporter APANTHERPTHR19229ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCAcoord: 1..141
NoneNo IPR availablePANTHERPTHR19229:SF216ATP-BINDING CASSETTE, SUB-FAMILY A (ABC1), MEMBER 1Acoord: 1..141
NoneNo IPR availableTMHMMTMhelixcoord: 82..104
NoneNo IPR availableTMHMMTMhelixcoord: 39..61
NoneNo IPR availableTMHMMTMhelixcoord: 7..29