Dynamin-type G domain-containing protein

Overview


Name	Dynamin-type G domain-containing protein
Smed ID	SMED30023988
Length (bp)	1929

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Dynamin-type G domain-containing protein (SMED30023988) t-SNE clustered cells

Violin plots show distribution of expression levels for Dynamin-type G domain-containing protein (SMED30023988) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dynamin-type G domain-containing protein (SMED30023988) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dynamin-type G domain-containing protein (SMED30023988) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30023988

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30023988	SMESG000002973.1	dd_Smed_v4_9275_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30023988	SMESG000002973.1	dd_Smed_v4_9275_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30023988	SMESG000002973.1	dd_Smed_v4_9275_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30023988	SMESG000002973.1	dd_Smed_v4_9275_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30023988	SMESG000002973.1	dd_Smed_v4_9275_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262])

HSP 1 Score: 133.265 bits (334), Expect = 2.036e-33
Identity = 80/254 (31.50%), Postives = 141/254 (55.51%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDPL-----FKARNASFEQF 926
            +  ++ R+  K   FGRTSSGKSS+INA+L +++LP+  G  +N F+ ++ +   K Y+    ++E K+++++ +L  +L  +  +K G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD    + +  + VR+Q+ME     L +EL   N     NRIFF SA E       KA+ + +  +     F AR   F+ F
Sbjct:   67 IGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNF 320

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262])

HSP 1 Score: 134.035 bits (336), Expect = 4.676e-32
Identity = 104/362 (28.73%), Postives = 180/362 (49.72%), Query Frame = 3

Query:  204 IIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDPL-----FKAR--------------------NASFEQFLITLKDELATLEHKKESDCL---NELYSLILKLFNNSNAVDLIMNKRNLNHQILKESIIETDKILTLECVTKTFNEIYEEFINKGNCLFNE 1190
            ++ R+  K   FGRTSSGKSS+INA+L +++LP+  G  +N F+ ++ +   K Y+    ++E K+++++ +L  +L  +  +K G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD    + +  + VR+Q+ME     L +EL   N     NRIFF SA E       KA+ + +  +     F AR                       FEQ  I  K  LAT+++  +S  L   ++ +  + +  +  + +D I N+ NL               LTL+ V K   E+ EE  NK +C   +
Sbjct:   70 VLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNL---------------LTLD-VKKKIKEVTEEVANKVSCAMTD 415

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Query:  204 IIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDPL-----FKAR--------------------NASFEQFLITLKDELATLEHKKESDCL---NELYSLILKLFNNSNAVDLIMNKRNLNHQILKESIIETDKILTLECVTKTFNEIYEEFINKGNCLFNE 1190
            ++ R+  K   FGRTSSGKSS+INA+L +++LP+  G  +N F+ ++ +   K Y+    ++E K+++++ +L  +L  +  +K G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD    + +  + VR+Q+ME     L +EL   N     NRIFF SA E       KA+ + +  +     F AR                       FEQ  I  K  LAT+++  +S  L   ++ +  + +  +  + +D I N+ NL               LTL+ V K   E+ EE  NK +C   +
Sbjct:   70 VLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNL---------------LTLD-VKKKIKEVTEEVANKVSCAMTD 415

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN2 (mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877])

HSP 1 Score: 130.183 bits (326), Expect = 7.235e-31
Identity = 70/221 (31.67%), Postives = 130/221 (58.82%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEG-HIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNEN-VSNRIFFFSAFE 842
            +  ++ R+  K   FGRTS+GKS++INA+L +++LP+  G T+N F++++ +   + ++      E ++ +++ +L   L +   +  GS V + +   KC LLK+++ ++D+PGID  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + S+ ++ I+ N WD    + +  + VR+Q+ME  T  L DELG  + +   +RIFF SA E
Sbjct:   88 ISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKE 308

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Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEG-HIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNEN-VSNRIFFFSAFE 842
            +  ++ R+  K   FGRTS+GKS++INA+L +++LP+  G T+N F++++ +   + ++      E ++ +++ +L   L +   +  GS V + +   KC LLK+++ ++D+PGID  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + S+ ++ I+ N WD    + +  + VR+Q+ME  T  L DELG  + +   +RIFF SA E
Sbjct:   88 ISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKE 308

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
Match: fzo-1 (Transmembrane GTPase fzo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q23424])

HSP 1 Score: 114.775 bits (286), Expect = 2.472e-26
Identity = 80/282 (28.37%), Postives = 153/282 (54.26%), Query Frame = 3

Query:   48 IYRELCGTLVDDIKKFENSCKELKKIFYPIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDL----------FYDPEK-----CNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNEN-VSNRIFFFSAFE 842
            +  ++ G L D++ + E   K++K+  +   ++  + ++I +  +   D      R   K V FGRTS+GKS+ INA+L E++LP   G T+  F+Q++ S  +  ++++++  + I+ ++ L  +   GH     + DL           + P+K     C LL+ ++ I+D+PG+D   +FD+ + ++  D ++ +LV N+ S ++  EK F  +   K SK ++ I+ N WD    + +N + V+KQ++    + L DEL   +E  V++RIFF S+ E
Sbjct:   46 VLGDVYGELKDNVAELEGVYKDIKENDFVSSEQREEIEAIGDSIKTIMD---TFQRDNMKVVFFGRTSNGKSTTINAMLHEKVLPQGMGHTTCCFLQVEGSEGEVGHLQLDDNPQKID-MKMLGKI---GHALSDENSDLPAMGQDSLLKVFHPKKSESGECRLLQNDVVILDSPGVDLSPEFDSWIDKHCLDADVFVLVSNAESTLTQAEKNFFLRVAKKLSKPNVFILNNRWDASAAETENIEDVKKQHLTRFRQFLVDELEVCSEREVNDRIFFVSSRE 320

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070910)

HSP 1 Score: 140.198 bits (352), Expect = 2.489e-34
Identity = 75/234 (32.05%), Postives = 139/234 (59.40%), Query Frame = 3

Query:  183 QAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAK 872
            + A ++ ++ R   K   FGRTS+GKSS+INA+L E+ILP+  G T+N F Q++ S+  + Y+      E   + ++++L + LC+  + + S V +F+  E+C+LL++++  +D+PG+D  +  D+ +  +  + ++ +LV+N+ S ++  EK+F      K SK ++ I+ N WD   ++ + +++V+ Q+ E     LT EL  SNE   + R+FF SA E  +    +AK
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAK 358

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070909)

HSP 1 Score: 140.198 bits (352), Expect = 2.489e-34
Identity = 75/234 (32.05%), Postives = 139/234 (59.40%), Query Frame = 3

Query:  183 QAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAK 872
            + A ++ ++ R   K   FGRTS+GKSS+INA+L E+ILP+  G T+N F Q++ S+  + Y+      E   + ++++L + LC+  + + S V +F+  E+C+LL++++  +D+PG+D  +  D+ +  +  + ++ +LV+N+ S ++  EK+F      K SK ++ I+ N WD   ++ + +++V+ Q+ E     LT EL  SNE   + R+FF SA E  +    +AK
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAK 358

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: fzo (gene:FBgn0011596 transcript:FBtr0084399)

HSP 1 Score: 139.428 bits (350), Expect = 2.987e-34
Identity = 78/247 (31.58%), Postives = 143/247 (57.89%), Query Frame = 3

Query:  135 IMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSS-KKEYIRINNEVKTIE--SLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPD--KAKNRDAVRKQYMESATKLLTDELG-YSN-ENVSNRIFFFSAFERTKI 854
            ++K+ +  + +  F  +   + +++ R   K   FGRTS+GKS++INALL E+ILP++ G T++ F Q++A+ S + E++++  E + +E  +L +L S    G +K  + + +     +C++L  ++ ++DTPG+D  ++ D+ +  Y  D ++ ILV+N+ S +S +E++F +    K S+ +L I+ N WD     + +    V+ Q+ME    LL DELG YS  +    RI+  SA E   I
Sbjct:   58 LLKDRQMLEHLCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQEDEHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHI 304

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0343373)

HSP 1 Score: 136.732 bits (343), Expect = 3.411e-33
Identity = 77/238 (32.35%), Postives = 138/238 (57.98%), Query Frame = 3

Query:  183 QAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF----PDKAKNRDA-VRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAK 872
            + A ++ ++ R   K   FGRTS+GKSS+INA+L E+ILP+  G T+N F Q++ S+  + Y+      E   + ++++L + LC+  + + S V +F+  E+C+LL++++  +D+PG+D  +  D+ +  +  + ++ +LV+N+ S ++  EK+F      K SK ++ I+ N WD     P+  ++  A V+ Q+ E     LT EL  SNE   + R+FF SA E  +    +AK
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAK 362

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: MFN1 (mitofusin 1a [Source:NCBI gene;Acc:100329462])

HSP 1 Score: 132.109 bits (331), Expect = 1.112e-32
Identity = 79/224 (35.27%), Postives = 129/224 (57.59%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEGHIKD-GSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF----PDKAKNRDAVRKQYMESATKLLTDELGYSNEN-VSNRIFFFSAFE 842
            +K ++ R+  K   FGRTS+GKS++INA+L E +LP+  G T+N F+ ++ +  ++ Y+   +  E K IE++  L   L     +D G  V +F+   KC LL++++ ++D+PGID  S+ D+ + ++  D ++ +LV NS S I   EK F  K   + SK ++ I+ N WD     P+  ++   VRKQ+M+     L DEL   + N   +RIFF SA E
Sbjct:   68 IKDVLDRRHMKVAFFGRTSNGKSTIINAMLRERVLPSGIGHTTNCFLSVEGTDGEQAYLTTEDSEERKGIETVNHLAHALHMNRNQDSGCLVRVFWPKTKCVLLRDDLVLMDSPGIDVTSELDSWIDKFCLDADVFVLVANSESTIMNTEKHFFHKVNERISKPNIFILNNRWDASVLEPEYLED---VRKQHMDRCVSFLVDELKVVDLNKAPDRIFFVSAKE 288

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44])

HSP 1 Score: 132.88 bits (333), Expect = 7.386e-32
Identity = 81/275 (29.45%), Postives = 154/275 (56.00%), Query Frame = 3

Query:  132 PIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELTSLLCEGHIKD-GSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDP-----LFKARNASFEQF 926
            P+  E  +   +  +  + A +  ++ R+  K V FGRTS+GKSS+INA+L +++LP+  G T+N F++++ +   + ++    ++E K+++++ +L   L +    D GS V + +   KC LL++++ ++D+PGID  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + S  ++ I+ N WD   ++ +  + VR+Q+M+  T  L DEL   +  +  +RIFF SA E  +    KA+ + +        F+AR   F+ F
Sbjct:   68 PVTTEE-QVAEVRGYLSKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNESFLLTEGSDERKSVKTVNQLAHALHQDEDLDAGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASANEPEYMEEVRRQHMDRCTSFLVDELRVVDRSHAGDRIFFVSAKEVLQARVQKAQGMPEAGGALAEGFQARMFEFQNF 341

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 125.561 bits (314), Expect = 2.666e-31
Identity = 76/252 (30.16%), Postives = 140/252 (55.56%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDPL---FKARNASFEQF 926
            ++ ++ R+  K   FGRTS+GKS++INA+L + +LP+  G T+N F+ ++ +   K +++     E K+I+++ +L  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   K SK ++ I+ N WD    + +  + VRKQ+ +     L +EL   +     NRIFF SA E   + +S+ +  +   L   F+ R   F+ F
Sbjct:   68 IQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKE---VLNSRMQRAQGGALAEGFQDRLKEFQNF 316

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 124.79 bits (312), Expect = 6.136e-31
Identity = 72/237 (30.38%), Postives = 134/237 (56.54%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDP 890
            ++ ++ R+  K   FGRTS+GKS++INA+L + +LP+  G T+N F+ ++ +   K +++     E K+I+++ +L  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   K SK ++ I+ N WD    + +  + VRKQ+ +     L +EL   +     NRIFF SA E   + +S+ +  +  P
Sbjct:   68 IQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKE---VLNSRMQRAQGMP 301

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 125.946 bits (315), Expect = 1.112e-29
Identity = 77/262 (29.39%), Postives = 146/262 (55.73%), Query Frame = 3

Query:  165 IYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDPL---FKARNASFEQF 926
            I ++  + + ++ ++ R+  K   FGRTS+GKS++INA+L + +LP+  G T+N F+ ++ +   K +++   + E K+I+++ +L  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   K SK ++ I+ N WD    + +  + VRKQ+ +     L +EL   +     NRIFF SA E   + +S+ +  +   L   F+ R   F+ F
Sbjct:   58 IESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKE---VLNSRMQRAQGGALAEGFQDRLKEFQNF 316

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 127.872 bits (320), Expect = 3.843e-30
Identity = 73/223 (32.74%), Postives = 128/223 (57.40%), Query Frame = 3

Query:  189 ADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFE 842
            A +  ++ R+  K   FGRTSSGKS++IN++L +++LP+  G T+N F+ ++ +   K Y+    + E K+++++ +L  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   K SK ++ I+ N WD    + +  + VRKQ+ME     L DEL   +      RIFF SA E
Sbjct:   81 AGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKE 303

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 127.872 bits (320), Expect = 4.026e-30
Identity = 73/223 (32.74%), Postives = 128/223 (57.40%), Query Frame = 3

Query:  189 ADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFE 842
            A +  ++ R+  K   FGRTSSGKS++IN++L +++LP+  G T+N F+ ++ +   K Y+    + E K+++++ +L  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   K SK ++ I+ N WD    + +  + VRKQ+ME     L DEL   +      RIFF SA E
Sbjct:   66 AGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKE 288

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 127.872 bits (320), Expect = 4.165e-30
Identity = 73/223 (32.74%), Postives = 128/223 (57.40%), Query Frame = 3

Query:  189 ADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFE 842
            A +  ++ R+  K   FGRTSSGKS++IN++L +++LP+  G T+N F+ ++ +   K Y+    + E K+++++ +L  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   K SK ++ I+ N WD    + +  + VRKQ+ME     L DEL   +      RIFF SA E
Sbjct:   76 AGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKE 298

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 127.487 bits (319), Expect = 4.890e-30
Identity = 73/223 (32.74%), Postives = 128/223 (57.40%), Query Frame = 3

Query:  189 ADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFE 842
            A +  ++ R+  K   FGRTSSGKS++IN++L +++LP+  G T+N F+ ++ +   K Y+    + E K+++++ +L  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   K SK ++ I+ N WD    + +  + VRKQ+ME     L DEL   +      RIFF SA E
Sbjct:   66 AGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKE 288

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 127.487 bits (319), Expect = 4.955e-30
Identity = 73/223 (32.74%), Postives = 128/223 (57.40%), Query Frame = 3

Query:  189 ADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFE 842
            A +  ++ R+  K   FGRTSSGKS++IN++L +++LP+  G T+N F+ ++ +   K Y+    + E K+++++ +L  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   K SK ++ I+ N WD    + +  + VRKQ+ME     L DEL   +      RIFF SA E
Sbjct:   81 AGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKE 303

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn1 (mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664])

HSP 1 Score: 135.961 bits (341), Expect = 6.995e-33
Identity = 106/367 (28.88%), Postives = 183/367 (49.86%), Query Frame = 3

Query:  165 IYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELG-YSNENVSNRIFFFSAFERTKIFSSKAKTVRKDP--------LFKARNASFEQFLITLKD-----------ELATLEHKKESDCLNELYSLILKLFNNSNAVDLIMNKRNLNHQILKESIIETD-KILTLECVTKTFNEIYEEFINKGNCLFNE 1190
            I  +  + A +  ++ R+  K   FGRTSSGKSS+INA+L +++LP+  G T+N F+ ++ +   K Y+    ++E K+++++ +L  +L  +  +K G  V +F+   KC LL++++ ++D+PG D  ++ D  + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD    + +  + VR+Q+ME     L +EL   S     NRIFF SA E   + +S+    +  P         F+AR   F+ F  T ++           E  T+  K+  D +      IL   N + A   + +      QI +   I     +LTL+ V K   E+ EE  NK +C   +
Sbjct:   57 IQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPSEARNRIFFVSAKE---VLNSRKHKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKN----ILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTLD-VKKKIKEVTEEVANKVSCAMTD 415

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Query:  165 IYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELG-YSNENVSNRIFFFSAFERTKIFSSKAKTVRKDP--------LFKARNASFEQFLITLKD-----------ELATLEHKKESDCLNELYSLILKLFNNSNAVDLIMNKRNLNHQILKESIIETD-KILTLECVTKTFNEIYEEFINKGNCLFNE 1190
            I  +  + A +  ++ R+  K   FGRTSSGKSS+INA+L +++LP+  G T+N F+ ++ +   K Y+    ++E K+++++ +L  +L  +  +K G  V +F+   KC LL++++ ++D+PG D  ++ D  + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD    + +  + VR+Q+ME     L +EL   S     NRIFF SA E   + +S+    +  P         F+AR   F+ F  T ++           E  T+  K+  D +      IL   N + A   + +      QI +   I     +LTL+ V K   E+ EE  NK +C   +
Sbjct:   57 IQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPSEARNRIFFVSAKE---VLNSRKHKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKN----ILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTLD-VKKKIKEVTEEVANKVSCAMTD 415

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230])

HSP 1 Score: 134.806 bits (338), Expect = 9.979e-33
Identity = 73/237 (30.80%), Postives = 137/237 (57.81%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEG-HIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDP 890
            +  ++ R+  K   FGRTS+GKS++INA+L +++LP+  G T+N F+++  +   + ++      E K+++++ +L   L +   +  GS V + +   KC LLK+++ ++D+PGID  ++ D+ + ++  D ++ +LV NS S +   EK+F  K   + S+ ++ I+ N WD    + +  + VR+Q+ME  T  L DELG  +     +RIFF SA E   + S++ +  +  P
Sbjct:   88 ISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKE---VLSARVQKAQGMP 321

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230])

HSP 1 Score: 134.806 bits (338), Expect = 1.858e-32
Identity = 73/237 (30.80%), Postives = 137/237 (57.81%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEG-HIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDP 890
            +  ++ R+  K   FGRTS+GKS++INA+L +++LP+  G T+N F+++  +   + ++      E K+++++ +L   L +   +  GS V + +   KC LLK+++ ++D+PGID  ++ D+ + ++  D ++ +LV NS S +   EK+F  K   + S+ ++ I+ N WD    + +  + VR+Q+ME  T  L DELG  +     +RIFF SA E   + S++ +  +  P
Sbjct:   88 ISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKE---VLSARVQKAQGMP 321

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230])

HSP 1 Score: 134.806 bits (338), Expect = 1.858e-32
Identity = 73/237 (30.80%), Postives = 137/237 (57.81%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEG-HIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDP 890
            +  ++ R+  K   FGRTS+GKS++INA+L +++LP+  G T+N F+++  +   + ++      E K+++++ +L   L +   +  GS V + +   KC LLK+++ ++D+PGID  ++ D+ + ++  D ++ +LV NS S +   EK+F  K   + S+ ++ I+ N WD    + +  + VR+Q+ME  T  L DELG  +     +RIFF SA E   + S++ +  +  P
Sbjct:   88 ISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKE---VLSARVQKAQGMP 321

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BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7YU24|MARF_DROME (Transmembrane GTPase Marf OS=Drosophila melanogaster OX=7227 GN=Marf PE=1 SV=1)

HSP 1 Score: 140.198 bits (352), Expect = 2.495e-33
Identity = 75/234 (32.05%), Postives = 139/234 (59.40%), Query Frame = 3

Query:  183 QAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAK 872
            + A ++ ++ R   K   FGRTS+GKSS+INA+L E+ILP+  G T+N F Q++ S+  + Y+      E   + ++++L + LC+  + + S V +F+  E+C+LL++++  +D+PG+D  +  D+ +  +  + ++ +LV+N+ S ++  EK+F      K SK ++ I+ N WD   ++ + +++V+ Q+ E     LT EL  SNE   + R+FF SA E  +    +AK
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAK 358

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BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|O18412|FZO_DROME (Transmembrane GTPase fzo OS=Drosophila melanogaster OX=7227 GN=fzo PE=1 SV=2)

HSP 1 Score: 139.428 bits (350), Expect = 2.995e-33
Identity = 78/247 (31.58%), Postives = 143/247 (57.89%), Query Frame = 3

Query:  135 IMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSS-KKEYIRINNEVKTIE--SLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPD--KAKNRDAVRKQYMESATKLLTDELG-YSN-ENVSNRIFFFSAFERTKI 854
            ++K+ +  + +  F  +   + +++ R   K   FGRTS+GKS++INALL E+ILP++ G T++ F Q++A+ S + E++++  E + +E  +L +L S    G +K  + + +     +C++L  ++ ++DTPG+D  ++ D+ +  Y  D ++ ILV+N+ S +S +E++F +    K S+ +L I+ N WD     + +    V+ Q+ME    LL DELG YS  +    RI+  SA E   I
Sbjct:   58 LLKDRQMLEHLCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQEDEHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHI 304

[Close]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q811U4|MFN1_MOUSE (Mitofusin-1 OS=Mus musculus OX=10090 GN=Mfn1 PE=1 SV=3)

HSP 1 Score: 135.961 bits (341), Expect = 4.893e-32
Identity = 106/367 (28.88%), Postives = 183/367 (49.86%), Query Frame = 3

Query:  165 IYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELG-YSNENVSNRIFFFSAFERTKIFSSKAKTVRKDP--------LFKARNASFEQFLITLKD-----------ELATLEHKKESDCLNELYSLILKLFNNSNAVDLIMNKRNLNHQILKESIIETD-KILTLECVTKTFNEIYEEFINKGNCLFNE 1190
            I  +  + A +  ++ R+  K   FGRTSSGKSS+INA+L +++LP+  G T+N F+ ++ +   K Y+    ++E K+++++ +L  +L  +  +K G  V +F+   KC LL++++ ++D+PG D  ++ D  + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD    + +  + VR+Q+ME     L +EL   S     NRIFF SA E   + +S+    +  P         F+AR   F+ F  T ++           E  T+  K+  D +      IL   N + A   + +      QI +   I     +LTL+ V K   E+ EE  NK +C   +
Sbjct:   57 IQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPSEARNRIFFVSAKE---VLNSRKHKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKN----ILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTLD-VKKKIKEVTEEVANKVSCAMTD 415

[Close]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q80U63|MFN2_MOUSE (Mitofusin-2 OS=Mus musculus OX=10090 GN=Mfn2 PE=1 SV=3)

HSP 1 Score: 134.806 bits (338), Expect = 1.300e-31
Identity = 73/237 (30.80%), Postives = 137/237 (57.81%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEG-HIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDP 890
            +  ++ R+  K   FGRTS+GKS++INA+L +++LP+  G T+N F+++  +   + ++      E K+++++ +L   L +   +  GS V + +   KC LLK+++ ++D+PGID  ++ D+ + ++  D ++ +LV NS S +   EK+F  K   + S+ ++ I+ N WD    + +  + VR+Q+ME  T  L DELG  +     +RIFF SA E   + S++ +  +  P
Sbjct:   88 ISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKE---VLSARVQKAQGMP 321

[Close]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8R4Z9|MFN1_RAT (Mitofusin-1 OS=Rattus norvegicus OX=10116 GN=Mfn1 PE=1 SV=1)

HSP 1 Score: 134.42 bits (337), Expect = 1.624e-31
Identity = 104/366 (28.42%), Postives = 179/366 (48.91%), Query Frame = 3

Query:  165 IYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELG-YSNENVSNRIFFFSAFERTKIFSSKAKTVRKDP--------LFKARNASFEQFLITLKD-----------ELATLEHKKESDCLNELYSLILKLFNNSNAVDLIMNKRNLNHQILKESIIETDKILTLECVTKTFNEIYEEFINKGNCLFNE 1190
            I  +  + A +  ++ R+  K   FGRTSSGKSS+INA+L +++LP+  G T+N F+ ++ +   K Y+    ++E K+++++ +L  +L  +  +K G  V +F+   KC LL++++ ++D+PG D  ++ D  + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD    + +  + VR+Q+ME     L +EL   S     NRIFF SA E   + +S+    +  P         F+AR   F+ F  T ++           E  T+  K+  D +      IL   N + A   + +      QI +   I     L    V K   E+ EE  NK +C   +
Sbjct:   57 IQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPLEARNRIFFVSAKE---VLNSRMNKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKN----ILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTMDVKKKIKEVTEEVANKVSCAMTD 415

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BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A1I8G8S1 (Dynamin-type G domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 155.992 bits (393), Expect = 3.416e-36
Identity = 87/255 (34.12%), Postives = 145/255 (56.86%), Query Frame = 3

Query:   90 KFENSCKELKKIFYPIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPD-KAKNRDAVRKQYMESATKLLTDEL-GYSNENVSNRIFFFSAFE 842
            K E +C    +I  P        QS+ +F  +   ++ +I R   KC  FGRTS+GKS++INA+L  ++LP+  G T+N F+Q++ +S +  Y++  N  E + IES+ +L S L    +   S V +F+  + C+LL+E++ ++D+PG+D     D  + Q+  D ++ ILV NS S +   EK+F  K G K SK ++ ++ N WD  D +  + + VRKQ+M+ +   L DEL   +     +R++F SA E
Sbjct:   95 KVEEAC--FARILTPAA-----VQSVTDFRAKVRGIREVISRNQMKCAFFGRTSNGKSTVINAMLGRKVLPSGIGHTTNCFLQVEGTSKQSAYLQTPNSSEEQPIESVSQLGSALSNEKMDCESLVRVFWPKQLCSLLREDVVLLDSPGVDVSPDLDTWIDQFCMDADVFILVCNSESTLMNTEKKFFHKVGSKLSKPNVFVLNNRWDCSDGELDSAELVRKQHMDKSVSFLADELKSCTRSEAESRVYFVSAKE 342

[Close]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A1I8G586 (Dynamin-type G domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 155.992 bits (393), Expect = 3.577e-36
Identity = 87/255 (34.12%), Postives = 145/255 (56.86%), Query Frame = 3

Query:   90 KFENSCKELKKIFYPIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPD-KAKNRDAVRKQYMESATKLLTDEL-GYSNENVSNRIFFFSAFE 842
            K E +C    +I  P        QS+ +F  +   ++ +I R   KC  FGRTS+GKS++INA+L  ++LP+  G T+N F+Q++ +S +  Y++  N  E + IES+ +L S L    +   S V +F+  + C+LL+E++ ++D+PG+D     D  + Q+  D ++ ILV NS S +   EK+F  K G K SK ++ ++ N WD  D +  + + VRKQ+M+ +   L DEL   +     +R++F SA E
Sbjct:   95 KVEEAC--FSRILTPAA-----VQSVTDFRAKVRGIREVISRNQMKCAFFGRTSNGKSTVINAMLGRKVLPSGIGHTTNCFLQVEGTSKQSAYLQTPNSSEEQPIESVSQLGSALSNEKMDCESLVRVFWPKQLCSLLREDVVLLDSPGVDVSPDLDTWIDQFCMDADVFILVCNSESTLMNTEKKFFHKVGSKLSKPNVFVLNNRWDCSDGELDSAELVRKQHMDKSVSFLADELKSCTRSEAESRVYFVSAKE 342

[Close]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A267FVL4 (Dynamin-type G domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018288g1 PE=3 SV=1)

HSP 1 Score: 156.377 bits (394), Expect = 4.358e-36
Identity = 87/255 (34.12%), Postives = 145/255 (56.86%), Query Frame = 3

Query:   90 KFENSCKELKKIFYPIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPD-KAKNRDAVRKQYMESATKLLTDEL-GYSNENVSNRIFFFSAFE 842
            K E +C    +I  P        QS+ +F  +   ++ +I R   KC  FGRTS+GKS++INA+L  ++LP+  G T+N F+Q++ +S +  Y++  N  E + IES+ +L S L    +   S V +F+  + C+LL+E++ ++D+PG+D     D  + Q+  D ++ ILV NS S +   EK+F  K G K SK ++ ++ N WD  D +  + + VRKQ+M+ +   L DEL   +     +R++F SA E
Sbjct:   93 KVEEAC--FARILTPAA-----VQSVTDFRAKVRGIREVISRNQMKCAFFGRTSNGKSTVINAMLGRKVLPSGIGHTTNCFLQVEGTSKQSAYLQTPNSSEEQPIESVSQLGSALSNEKMDCESLVRVFWPKQLCSLLREDVVLLDSPGVDVSPDLDTWIDQFCMDADVFILVCNSESTLMNTEKKFFHKVGSKLSKPNVFVLNNRWDCSDGELDSAELVRKQHMDKSVSFLADELKSCTRSEAESRVYFVSAKE 340

[Close]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A267FP40 (Dynamin-type G domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig004622g1 PE=3 SV=1)

HSP 1 Score: 155.992 bits (393), Expect = 4.480e-36
Identity = 87/255 (34.12%), Postives = 145/255 (56.86%), Query Frame = 3

Query:   90 KFENSCKELKKIFYPIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPD-KAKNRDAVRKQYMESATKLLTDEL-GYSNENVSNRIFFFSAFE 842
            K E +C    +I  P        QS+ +F  +   ++ +I R   KC  FGRTS+GKS++INA+L  ++LP+  G T+N F+Q++ +S +  Y++  N  E + IES+ +L S L    +   S V +F+  + C+LL+E++ ++D+PG+D     D  + Q+  D ++ ILV NS S +   EK+F  K G K SK ++ ++ N WD  D +  + + VRKQ+M+ +   L DEL   +     +R++F SA E
Sbjct:   93 KVEEAC--FSRILTPAA-----VQSVTDFRAKVRGIREVISRNQMKCAFFGRTSNGKSTVINAMLGRKVLPSGIGHTTNCFLQVEGTSKQSAYLQTPNSSEEQPIESVSQLGSALSNEKMDCESLVRVFWPKQLCSLLREDVVLLDSPGVDVSPDLDTWIDQFCMDADVFILVCNSESTLMNTEKKFFHKVGSKLSKPNVFVLNNRWDCSDGELDSAELVRKQHMDKSVSFLADELKSCTRSEAESRVYFVSAKE 340

[Close]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A1I8HVZ8 (Dynamin-type G domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 4.551e-36
Identity = 87/255 (34.12%), Postives = 145/255 (56.86%), Query Frame = 3

Query:   90 KFENSCKELKKIFYPIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPD-KAKNRDAVRKQYMESATKLLTDEL-GYSNENVSNRIFFFSAFE 842
            K E +C    +I  P        QS+ +F  +   ++ +I R   KC  FGRTS+GKS++INA+L  ++LP+  G T+N F+Q++ +S +  Y++  N  E + IES+ +L S L    +   S V +F+  + C+LL+E++ ++D+PG+D     D  + Q+  D ++ ILV NS S +   EK+F  K G K SK ++ ++ N WD  D +  + + VRKQ+M+ +   L DEL   +     +R++F SA E
Sbjct:   93 KVEEAC--FSRILTPAA-----VQSVTDFRAKVRGIREVISRNQMKCAFFGRTSNGKSTVINAMLGRKVLPSGIGHTTNCFLQVEGTSKESAYLQTPNSSEERPIESVSQLGSALSNEKLDCESLVRVFWPKQLCSLLREDVVLLDSPGVDVSPDLDTWIDQFCMDADVFILVCNSESTLMNTEKKFFHKVGSKLSKPNVFVLNNRWDCSDGELDSAELVRKQHMDKSVSFLADELKSCTRSEAESRVYFVSAKE 340

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000043809.1 (mitofusin-1-like [Source:NCBI gene;Acc:103034819])

HSP 1 Score: 136.732 bits (343), Expect = 2.785e-33
Identity = 81/254 (31.89%), Postives = 141/254 (55.51%), Query Frame = 3

Query:   96 ENSCKELKKIFYPIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN--EVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPD-KAKNRDAVRKQYMESATKLLTDELG-YSNENVSNRIFFFSAFE 842
            E  C E++         +RK ++I+           ++ R+  K   FGRTS+GKS++INA+L E +LP+  G T+N F+ ++ +   + ++   N  E K+I+++ +L  +L  + ++  G  V +F+   KC LL++++ ++D+PG D  S+ D+ + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD  + + +  D VRKQ+M+     L DEL   S +   NRIFF SA E
Sbjct:   52 EEQCMEIQSC-------SRKLEAIWE----------VLARRQMKVAFFGRTSNGKSTVINAMLRERVLPSGIGHTTNCFISVEGTDGDQAFLTTENSEERKSIKTVNQLAHALHMDRNLDSGCLVRVFWPKTKCALLRDDLVLMDSPGTDVTSELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVSERISKPNIFILNNRWDASETEPEYLDGVRKQHMDRCVSFLVDELKVVSPDQAPNRIFFVSAKE 288

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239])

HSP 1 Score: 134.806 bits (338), Expect = 1.227e-32
Identity = 78/256 (30.47%), Postives = 146/256 (57.03%), Query Frame = 3

Query:  138 MKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSN-ENVSNRIFFFSAFERTKIFSSKAKTVRKDP 890
            + ++ + Q I ++ E+ A +K ++ R+  K   FGRTS+GKS++INA+L + +LP+  G T+N F+ ++ +   K Y++   + E K+I+++ +L  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD    + +  D VRKQ+ +     L +EL   + E   N IFF SA E   + +S+ +  +  P
Sbjct:   49 IADSTQLQEIESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHTDRCVNFLVEELKVVDREEAPNHIFFVSAKE---VLNSRMQRAQGMP 301

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239])

HSP 1 Score: 134.806 bits (338), Expect = 1.473e-32
Identity = 78/256 (30.47%), Postives = 146/256 (57.03%), Query Frame = 3

Query:  138 MKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSN-ENVSNRIFFFSAFERTKIFSSKAKTVRKDP 890
            + ++ + Q I ++ E+ A +K ++ R+  K   FGRTS+GKS++INA+L + +LP+  G T+N F+ ++ +   K Y++   + E K+I+++ +L  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD    + +  D VRKQ+ +     L +EL   + E   N IFF SA E   + +S+ +  +  P
Sbjct:   49 IADSTQLQEIESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHTDRCVNFLVEELKVVDREEAPNHIFFVSAKE---VLNSRMQRAQGMP 301

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44])

HSP 1 Score: 134.42 bits (337), Expect = 1.994e-32
Identity = 82/275 (29.82%), Postives = 152/275 (55.27%), Query Frame = 3

Query:  132 PIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELTSLLCEGHIKD-GSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDP-----LFKARNASFEQF 926
            P+  E  +   +  +  + A +  ++ R+  K V FGRTS+GKSS+INA+L +++LP+  G T+N F++++ +   + ++    + E K ++++ +L   L +    D GS V + +   KC LL++++ ++D+PGID  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + S  ++ I+ N WD    + +  + VR+Q+M+  +  L DELG  +    S+RIFF SA E  +    KA+ + +        F+AR   F+ F
Sbjct:   68 PVTTEE-QVAEVRGYLSKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNEAFLLTEGSEERKNVKTVNQLAHALHQDEDLDAGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMEEVRRQHMDRCSSFLVDELGVVDRAQASDRIFFVSAKEVLQARVQKAQGMPEAGGALAEGFQARMFEFQNF 341

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Yeast
Match: FZO1 (Mitofusin; integral membrane protein involved in mitochondrial outer membrane tethering and fusion; role in mitochondrial genome maintenance; efficient tethering and degradation of Fzo1p requires an intact N-terminal GTPase domain; targeted for destruction by the ubiquitin ligase SCF-Mdm30p and the cytosolic ubiquitin-proteasome system [Source:SGD;Acc:S000000383])

HSP 1 Score: 55.0694 bits (131), Expect = 3.080e-8
Identity = 54/217 (24.88%), Postives = 99/217 (45.62%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSF-----------------VQIKASSSKKEYIRI----NNEVKTIESLRELTSLLCEG--------HIKDGSHVDLFYDPEKCNLLKE---NIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQ 749
            LK+ +     K  + G  ++GKS+L N+LL + +LP      +N F                 + +  + + KE I +    N +   I +L+EL  L+ +         +IKD         P   +LL+    +I +ID+PG++ DS     V+   ++++L+I VVN+ + ++L  KEF+     +  KL   +V       DK + ++ + KQ
Sbjct:  179 LKKRVDDVSSKVFITGDVNTGKSALCNSLLKQRLLPEDQLPCTNVFSEILEARENDGIEEVHAIPLNIAPTLKEAIDMYSIQNPKTYEIHTLKELPDLVPQNGKYALLKIYIKDDKR------PASTSLLRNGTVDISLIDSPGLNMDSLQTAEVMSRQEEIDLVIFVVNAENQLTLSAKEFI-SLASREKKLMFFVVKKFDKIRDKQRCKELILKQ 388

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
Match: EDO42379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1L1])

HSP 1 Score: 129.413 bits (324), Expect = 3.075e-31
Identity = 74/233 (31.76%), Postives = 127/233 (54.51%), Query Frame = 3

Query:  165 IYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF----PDKAKNRDAVRKQYMESATKLLTDELG-YSNENVSNRIFFFSAFE 842
            +  F  Q A +  +I R   K   FGRTS+GKS+++NA+L + ILP   G T+N F+ +  S S   YI I  ++E + +++L ++   L E  +   S V +++   +C +L E++ ++D+PGID     D  + ++  D ++ +LV N+ S + + EK F  K   K SK ++ I+ N WD     PD  +  + V+KQ+++     L+ EL     +   +R+FF SA E
Sbjct:   77 VAGFLGQVASITEVIARDQMKVAFFGRTSNGKSTVVNAMLQDRILPMGIGHTTNCFLSVNGSDSADPYILIPESDERRNVKTLGQIAHALFEEKLDHSSLVQVYWPKSRCKMLSEDVVLVDSPGIDVSPDLDLWIDKHCLDADVFVLVCNAESTLMVTEKNFFHKVNQKLSKPNIFILNNRWDASAGEPD-VEMMELVKKQHLQRNVDFLSKELKCVDKKQAEDRVFFVSAKE 308

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn2 (mitofusin 2 [Source:NCBI gene;Acc:101170481])

HSP 1 Score: 139.043 bits (349), Expect = 6.628e-34
Identity = 84/278 (30.22%), Postives = 155/278 (55.76%), Query Frame = 3

Query:  132 PIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELTSLLCEGHIKD-GSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSNE-NVSNRIFFFSAFERTKIFSSKAKTVRKDP--------LFKARNASFEQF 926
            P+  E  + Q +  F  + A +  ++ R+  K V FGRTS+GKS++INA+L +++LP+  G T+N F++++ +   + ++    + E K+I+++ +L   L +    D GS V + +   KC LL++++ ++D+PGID  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + S  ++ I+ N WD    + +  D VR+Q+M+  +  L +ELG  +    S+RIFF SA E   +  ++ + V+  P         F+AR   F+ F
Sbjct:   68 PVTAEE-QVQEVRGFLSKVAGIGEVLARRHMKVVFFGRTSNGKSTVINAMLCDKVLPSGIGHTTNCFLRVEGTDGSEGFLLTEGSEEKKSIKTVNQLAHALHQDQDLDAGSLVCVMWPKVKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMDEVRRQHMDRCSNFLVEELGVVDRAQASDRIFFVSAKE---VLQARMQRVQGMPEAGGALAEGFQARMFEFQNF 341

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009])

HSP 1 Score: 131.339 bits (329), Expect = 2.041e-31
Identity = 74/247 (29.96%), Postives = 143/247 (57.89%), Query Frame = 3

Query:  165 IYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSN-ENVSNRIFFFSAFERTKIFSSKAKTVRKDP 890
            I  + ++ A +K ++ R+  K   FGRTS+GKS++INA+L + +LP+  G T+N F+ ++ +   + Y++   ++E K+I+++ ++  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD   ++ +  + VRKQ+ +     L +EL   + E   NRIFF SA E   + +S+ +  +  P
Sbjct:   69 IQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSDEEKSIKTVNQMAHALHMDESLDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQHTDRCVNFLVEELKVVDREQAPNRIFFISAKE---VLNSRMQRAQGMP 312

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009])

HSP 1 Score: 130.954 bits (328), Expect = 2.371e-31
Identity = 74/247 (29.96%), Postives = 143/247 (57.89%), Query Frame = 3

Query:  165 IYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRI--NNEVKTIESLRELT-SLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGYSN-ENVSNRIFFFSAFERTKIFSSKAKTVRKDP 890
            I  + ++ A +K ++ R+  K   FGRTS+GKS++INA+L + +LP+  G T+N F+ ++ +   + Y++   ++E K+I+++ ++  +L  +  +  G  V +F+   KC LL++++ ++D+PG D  ++ D+ + ++  D ++ +LV NS S +   EK F  K   + SK ++ I+ N WD   ++ +  + VRKQ+ +     L +EL   + E   NRIFF SA E   + +S+ +  +  P
Sbjct:   69 IQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSDEEKSIKTVNQMAHALHMDESLDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQHTDRCVNFLVEELKVVDREQAPNRIFFISAKE---VLNSRMQRAQGMP 312

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000009003.2 (pep primary_assembly:ASM223467v1:17:11595384:11602171:-1 gene:ENSORLG00000007178.2 transcript:ENSORLT00000009003.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 119.783 bits (299), Expect = 2.841e-29
Identity = 73/240 (30.42%), Postives = 130/240 (54.17%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYI--RINNEVKTIESLRELTSLLCEGHIKDGSH-VDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF----PDKAKNRDAVRKQYMESATKLLTDELGYSNEN-VSNRIFFFSAFERTKIFSSKAKTVRKDP 890
            ++ ++ R+  K   FGRTS+GKS++INA+L + +LP+  G T+N F+ ++ +   + Y+    + E ++I ++ +L   L      D S  V +F+   +C LL+ ++ ++D+PG D   + D+ + ++  D ++ +LV N+ S +   EK F  K   + SK ++ I+ N WD     PD  +    VRKQ+++     L +ELG    N    RIFF SA E   + SS+ +  +  P
Sbjct:   66 IRDVLLRRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDGDEAYLTSEASEERRSISTVNQLAHALHMDPTLDSSCLVKVFWPKSRCALLRNDLVLMDSPGTDVTLELDSWIDKFCLDADVFVLVGNAESTLMNTEKLFFHKVSERISKPNIFILHNRWDASVTEPDYIQE---VRKQHLDRCVGFLAEELGVVGPNEAPGRIFFISAKE---VLSSRMQRAQGMP 299

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000002973.1 (SMESG000002973.1)

HSP 1 Score: 1139.02 bits (2945), Expect = 0.000e+0
Identity = 585/613 (95.43%), Postives = 597/613 (97.39%), Query Frame = 3

Query:   30 MSDDDNIYRELCGTLVDDIKKFENSCKELKKIFYPIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNRIFFFSAFERTKIFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNELYSLILKLFNNSNAVDLIMNKRNLNHQILKESIIETDKILTLECVTKTFNEIYEEFINKGNCLFNEFLNNEKHIDVTKVKEEINSKLKALFHGIAKCHEEQLKLFINKQIGESQNKNSTSWILTKFYFPNYFNFSHEILDHSVELSFFYNEMEKINQTINSGKKLTTMLSTCTTVAHXXXXXXXXXXXXXXXXXXRMAVAGLVGYGLSNAVIENMKTPFEHFWKHDAKSIRDYLDKLKIKFIYNYTEFKKSLCENFDSEFYENGIGIQNKLNDMKVKIQKFENKTDLLSHKS 1868
            MSD DNIYRELCGTLVDDIKKFENSCKELKKIFYPI+KENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFG+TSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKC+LLKENIEI+DTPGIDSDSKFDNSVVQYFKDVNLIILVVNS+SGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNRIFF SAFERT IFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNEL+SLILKLFNNSNAVDLIMNKRNL HQ LKESIIETDKILTLECVTKTFNEIYEEFINKGN LFN+FLNNEK I+VT+VKEEINSKLKAL H IAKCHEEQLKLFINKQIGESQNKNSTSWILTKFYFPNYFNFSHEILDHSVE +FFYNEMEKINQ INSGK LTTMLSTC TVA FGFGVATGGVLGLTLAAGRMAVAGLVGYGLSNAVIENMKTPFEH WKHDAKSIRDYLDKLK+KFIYNY EF+KSLCENFDSEFYENGIGIQNKLNDMKVKIQKFENKTDLLSHKS
Sbjct:    1 MSDYDNIYRELCGTLVDDIKKFENSCKELKKIFYPIIKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGKTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCSLLKENIEIVDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSLSGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNRIFFLSAFERTNIFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNELHSLILKLFNNSNAVDLIMNKRNLYHQSLKESIIETDKILTLECVTKTFNEIYEEFINKGNFLFNDFLNNEKRINVTQVKEEINSKLKALLHSIAKCHEEQLKLFINKQIGESQNKNSTSWILTKFYFPNYFNFSHEILDHSVESNFFYNEMEKINQKINSGKNLTTMLSTCATVATFGFGVATGGVLGLTLAAGRMAVAGLVGYGLSNAVIENMKTPFEHLWKHDAKSIRDYLDKLKMKFIYNYMEFQKSLCENFDSEFYENGIGIQNKLNDMKVKIQKFENKTDLLSHKS 613

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000002973.1 (SMESG000002973.1)

HSP 1 Score: 1138.25 bits (2943), Expect = 0.000e+0
Identity = 585/613 (95.43%), Postives = 597/613 (97.39%), Query Frame = 3

Query:   30 MSDDDNIYRELCGTLVDDIKKFENSCKELKKIFYPIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNRIFFFSAFERTKIFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNELYSLILKLFNNSNAVDLIMNKRNLNHQILKESIIETDKILTLECVTKTFNEIYEEFINKGNCLFNEFLNNEKHIDVTKVKEEINSKLKALFHGIAKCHEEQLKLFINKQIGESQNKNSTSWILTKFYFPNYFNFSHEILDHSVELSFFYNEMEKINQTINSGKKLTTMLSTCTTVAHXXXXXXXXXXXXXXXXXXRMAVAGLVGYGLSNAVIENMKTPFEHFWKHDAKSIRDYLDKLKIKFIYNYTEFKKSLCENFDSEFYENGIGIQNKLNDMKVKIQKFENKTDLLSHKS 1868
            MSD DNIYRELCGTLVDDIKKFENSCKELKKIFYPI+KENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFG+TSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKC+LLKENIEI+DTPGIDSDSKFDNSVVQYFKDVNLIILVVNS+SGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNRIFF SAFERT IFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNEL+SLILKLFNNSNAVDLIMNKRNL HQ LKESIIETDKILTLECVTKTFNEIYEEFINKGN LFN+FLNNEK I+VT+VKEEINSKLKAL H IAKCHEEQLKLFINKQIGESQNKNSTSWILTKFYFPNYFNFSHEILDHSVE +FFYNEMEKINQ INSGK LTTMLSTC TVA FGFGVATGGVLGLTLAAGRMAVAGLVGYGLSNAVIENMKTPFEH WKHDAKSIRDYLDKLK+KFIYNY EF+KSLCENFDSEFYENGIGIQNKLNDMKVKIQKFENKTDLLSHKS
Sbjct:    1 MSDYDNIYRELCGTLVDDIKKFENSCKELKKIFYPIIKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGKTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCSLLKENIEIVDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSLSGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNRIFFLSAFERTNIFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNELHSLILKLFNNSNAVDLIMNKRNLYHQSLKESIIETDKILTLECVTKTFNEIYEEFINKGNFLFNDFLNNEKRINVTQVKEEINSKLKALLHSIAKCHEEQLKLFINKQIGESQNKNSTSWILTKFYFPNYFNFSHEILDHSVESNFFYNEMEKINQKINSGKNLTTMLSTCATVATFGFGVATGGVLGLTLAAGRMAVAGLVGYGLSNAVIENMKTPFEHLWKHDAKSIRDYLDKLKMKFIYNYMEFQKSLCENFDSEFYENGIGIQNKLNDMKVKIQKFENKTDLLSHKS 613

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000002973.1 (SMESG000002973.1)

HSP 1 Score: 1135.17 bits (2935), Expect = 0.000e+0
Identity = 585/613 (95.43%), Postives = 597/613 (97.39%), Query Frame = 3

Query:   30 MSDDDNIYRELCGTLVDDIKKFENSCKELKKIFYPIMKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNRIFFFSAFERTKIFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNELYSLILKLFNNSNAVDLIMNKRNLNHQILKESIIETDKILTLECVTKTFNEIYEEFINKGNCLFNEFLNNEKHIDVTKVKEEINSKLKALFHGIAKCHEEQLKLFINKQIGESQNKNSTSWILTKFYFPNYFNFSHEILDHSVELSFFYNEMEKINQTINSGKKLTTMLSTCTTVAHXXXXXXXXXXXXXXXXXXRMAVAGLVGYGLSNAVIENMKTPFEHFWKHDAKSIRDYLDKLKIKFIYNYTEFKKSLCENFDSEFYENGIGIQNKLNDMKVKIQKFENKTDLLSHKS 1868
            MSD DNIYRELCGTLVDDIKKFENSCKELKKIFYPI+KENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFG+TSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKC+LLKENIEI+DTPGIDSDSKFDNSVVQYFKDVNLIILVVNS+SGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNRIFF SAFERT IFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNEL+SLILKLFNNSNAVDLIMNKRNL HQ LKESIIETDKILTLECVTKTFNEIYEEFINKGN LFN+FLNNEK I+VT+VKEEINSKLKAL H IAKCHEEQLKLFINKQIGESQNKNSTSWILTKFYFPNYFNFSHEILDHSVE +FFYNEMEKINQ INSGK LTTMLSTC TVA FGFGVATGGVLGLTLAAGRMAVAGLVGYGLSNAVIENMKTPFEH WKHDAKSIRDYLDKLK+KFIYNY EF+KSLCENFDSEFYENGIGIQNKLNDMKVKIQKFENKTDLLSHKS
Sbjct:    1 MSDYDNIYRELCGTLVDDIKKFENSCKELKKIFYPIIKENRKYQSIYNFDEQAADLKRIIHRKLKKCVVFGKTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCSLLKENIEIVDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSLSGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNRIFFLSAFERTNIFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNELHSLILKLFNNSNAVDLIMNKRNLYHQSLKESIIETDKILTLECVTKTFNEIYEEFINKGNFLFNDFLNNEKRINVTQVKEEINSKLKALLHSIAKCHEEQLKLFINKQIGESQNKNSTSWILTKFYFPNYFNFSHEILDHSVESNFFYNEMEKINQKINSGKNLTTMLSTCATVATFGFGVATGGVLGLTLAAGRMAVAGLVGYGLSNAVIENMKTPFEHLWKHDAKSIRDYLDKLKMKFIYNYMEFQKSLCENFDSEFYENGIGIQNKLNDMKVKIQKFENKTDLLSHKS 613

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000003246.1 (SMESG000003246.1)

HSP 1 Score: 177.948 bits (450), Expect = 1.126e-47
Identity = 179/591 (30.29%), Postives = 284/591 (48.05%), Query Frame = 3

Query:  195 LKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKAS-SSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLTDELGYSNENVSNRIFFFSAFERTKIFSSKAKTVRKDPLFKARNASFEQFLITLKDELATLEHKKESDCLNELYSLILKLFNNSNA-VDLIMNKR---------------NLNHQILKE-SIIETDKILTLECVTKTFNEIYEEFINKGNCLFNE----FLNNEKHIDVTKVKEEIN---SKLKALFHGIAKCHEEQLKLFINKQIGE-SQNKNST-SWILTK---FYFPNYFNFSHEILDHSVELSFFYNEMEKINQTINSGKKLTTMLSTCTTVAHXXXXXXXXXXXXXXXXXXRMAVAGLVGY--------GLSNAVIENMKTPFEHFWKHDAKSIRDYLDKLKIKFIYNYTEFKKSLCENFD---SEFYENGIGIQNKLNDMKVKIQKFENK 1844
            LK  ++   KK VV G+TSSGKS+LINA LTE +LPT  GSTSN F++IK S  S + Y+ +NNE K I+ L     ++       GS + ++YD  KC LL +++ IID+PGID D+   N + QYF+D ++IILVV+S++GI++ E    ++   K +K ++ IV+N WD    +     ++ +Y++ A K+L D L   +  + ++IFF SA ER  IF+++   +   P +  RN  F      L+ +++     K+   LN  Y   L  FN     +D + +KR               + N +I  E S I  D  + L    K   +   + +NK N   NE     L  E   D T   E +    ++ + L H I     E   L + K+I E SQ+ N   S++L K    YF  Y N S + L H  ++    N + +IN+ I     +T  L+   T A    G A   ++GL  AA   A A   G         G +   ++ +K PF   WK +  +I++  +  +     +Y  F+ ++  N     +      + I+N LN +   +  F N+
Sbjct:   68 LKSKLNNNDKKFVVLGKTSSGKSTLINAFLTENLLPTEFGSTSNCFIEIKGSLESNRNYLVVNNEEKDIDEL----GVINGSQEMMGSLITMYYDRAKCPLLGDDVIIIDSPGIDFDNLSVNLIDQYFRDSDVIILVVSSVTGITISEINLFKRLQSKLTKFNVAIVYNFWDVICSSHKDVLIKPRYIQEAKKILCDILRLPDNEIESKIFFISANERMAIFTNEVTAISA-PKWDERNNEFASLFSYLQRKMSESADCKKFADLNNTYLEALANFNKCRCLIDEMKDKRIELAAKLKNELKKLEDFNSKINSEISAIFNDSYIDLLIKGKELLKKNPQLLNKNNS--NEEKYPLLERETIQDQTVYGERLRLSENEFEELLHQII----ENSILKLTKRIIELSQSANDMDSFMLNKIFDIYFSQYLNLSEQ-LSH-FDVGSLENNLIEINRKIKIASGVTIGLTAAVTAAGIATGGAAFAIIGLAEAAIVGAGAAGGGAVAGGVLGSGAAFGAVKAVKLPFHFAWKENDLAIKNMWNSFESVLTDSYDRFRDNMTSNITEIITTIEAKAMKIRNNLNSIAEDLNNFPNR 645

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000000387.1 (SMESG000000387.1)

HSP 1 Score: 140.198 bits (352), Expect = 1.517e-34
Identity = 95/315 (30.16%), Postives = 156/315 (49.52%), Query Frame = 3

Query:   93 FENSCKELKKIFYPI----MKENRKYQSIYNFD-------------------EQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNSFVQIKASSSKKEYIRINN------------EVKTIESLRELTSLLCEGHIKDGSHVDLFYDPEKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISLIEKEFLRKFGGKFSKLHLLIVFNLWDF-PDKAKNRDAVRKQYMESATKLLTDELGY-SNENVSNRIFFFSAFERTKIFSSKAKTVRKDPLFKARNASFEQF 926
            F+ S  E+ KIF+ I    M  N  +  IYN D                   ++   ++ +I R   KC  FGRTS+GKS+ INA+L  +ILPT  G T++ F++I+ +   + +I+I++            + K I+S+++L   +    +   S + +F+  EKC LL +++ I+D+PGID D   D  +  Y  D ++ +LV NS S ++  EK F      K SK ++ I+ N WD   D+ +    VR+Q+ E     L+ EL   S     +R+FF SA E   + S KA++   D +    + S  + 
Sbjct:   16 FKESKTEIIKIFHDIAIYVMDSNTFFNEIYNSDAMFQSLINVDNVKLLVNFVDKVNGIQNVISRNNMKCAFFGRTSNGKSTTINAMLGGKILPTGIGHTTSCFLEIQGTDDNQGFIKISSPENINDESADVVDSKPIDSVKDLARDVSLNKLSSDSLIKIFWPNEKCPLLSQDVVILDSPGIDVDPDIDKWIDMYCLDADVFVLVANSESTLNHTEKSFFHNVSNKLSKPNIFILNNRWDASADQVEYVKEVREQHTEKCVAFLSKELKVCSKTEAESRVFFVSASEALNMRSRKAESSGGDSIAAGESPSLPKM 330

The following BLAST results are available for this feature:

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Sea Lamprey
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Yeast
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MFN1	2.036e-33	31.50	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN1	4.676e-32	28.73	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN1	4.676e-32	28.73	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN2	7.235e-31	31.67	mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]	[more]
MFN2	7.235e-31	31.67	mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
fzo-1	2.472e-26	28.37	Transmembrane GTPase fzo-1 [Source:UniProtKB/Swis...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Marf	2.489e-34	32.05	gene:FBgn0029870 transcript:FBtr0070910	[more]
Marf	2.489e-34	32.05	gene:FBgn0029870 transcript:FBtr0070909	[more]
fzo	2.987e-34	31.58	gene:FBgn0011596 transcript:FBtr0084399	[more]
Marf	3.411e-33	32.35	gene:FBgn0029870 transcript:FBtr0343373	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MFN1	1.112e-32	35.27	mitofusin 1a [Source:NCBI gene;Acc:100329462]	[more]
mfn2	7.386e-32	29.45	mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]	[more]
mfn1b	2.666e-31	30.16	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn1b	6.136e-31	30.38	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn1b	1.112e-29	29.39	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mfn1	3.843e-30	32.74	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	4.026e-30	32.74	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	4.165e-30	32.74	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	4.890e-30	32.74	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	4.955e-30	32.74	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mfn1	6.995e-33	28.88	mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664]	[more]
Mfn1	6.995e-33	28.88	mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664]	[more]
Mfn2	9.979e-33	30.80	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]
Mfn2	1.858e-32	30.80	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]
Mfn2	1.858e-32	30.80	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q7YU24\|MARF_DROME	2.495e-33	32.05	Transmembrane GTPase Marf OS=Drosophila melanogast...	[more]
sp\|O18412\|FZO_DROME	2.995e-33	31.58	Transmembrane GTPase fzo OS=Drosophila melanogaste...	[more]
sp\|Q811U4\|MFN1_MOUSE	4.893e-32	28.88	Mitofusin-1 OS=Mus musculus OX=10090 GN=Mfn1 PE=1 ...	[more]
sp\|Q80U63\|MFN2_MOUSE	1.300e-31	30.80	Mitofusin-2 OS=Mus musculus OX=10090 GN=Mfn2 PE=1 ...	[more]
sp\|Q8R4Z9\|MFN1_RAT	1.624e-31	28.42	Mitofusin-1 OS=Rattus norvegicus OX=10116 GN=Mfn1 ...	[more]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1I8G8S1	3.416e-36	34.12	Dynamin-type G domain-containing protein OS=Macros...	[more]
A0A1I8G586	3.577e-36	34.12	Dynamin-type G domain-containing protein OS=Macros...	[more]
A0A267FVL4	4.358e-36	34.12	Dynamin-type G domain-containing protein (Fragment...	[more]
A0A267FP40	4.480e-36	34.12	Dynamin-type G domain-containing protein (Fragment...	[more]
A0A1I8HVZ8	4.551e-36	34.12	Dynamin-type G domain-containing protein OS=Macros...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ENSAMXT00000043809.1	2.785e-33	31.89	mitofusin-1-like [Source:NCBI gene;Acc:103034819]	[more]
mfn1b	1.227e-32	30.47	mitofusin-1 [Source:NCBI gene;Acc:103030239]	[more]
mfn1b	1.473e-32	30.47	mitofusin-1 [Source:NCBI gene;Acc:103030239]	[more]
mfn2	1.994e-32	29.82	mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
FZO1	3.080e-8	24.88	Mitofusin; integral membrane protein involved in m...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO42379	3.075e-31	31.76	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
mfn2	6.628e-34	30.22	mitofusin 2 [Source:NCBI gene;Acc:101170481]	[more]
mfn1b	2.041e-31	29.96	mitofusin 1 [Source:NCBI gene;Acc:101158009]	[more]
mfn1b	2.371e-31	29.96	mitofusin 1 [Source:NCBI gene;Acc:101158009]	[more]
ENSORLT00000009003.2	2.841e-29	30.42	pep primary_assembly:ASM223467v1:17:11595384:11602...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000002973.1	0.000e+0	95.43	SMESG000002973.1	[more]
SMESG000002973.1	0.000e+0	95.43	SMESG000002973.1	[more]
SMESG000002973.1	0.000e+0	95.43	SMESG000002973.1	[more]
SMESG000003246.1	1.126e-47	30.29	SMESG000003246.1	[more]
SMESG000000387.1	1.517e-34	30.16	SMESG000000387.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30023988 ID=SMED30023988|Name=Dynamin-type G domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1929bp
CTAAATTCAAATCTATTTAATATATAATAATGAGTGATGATGATAATATT
TATCGTGAATTGTGCGGTACTCTCGTAGATGACATTAAAAAATTTGAAAA
TTCATGTAAAGAATTGAAAAAAATTTTCTATCCAATAATGAAAGAAAATA
GAAAATATCAATCAATTTATAATTTTGATGAGCAAGCTGCTGATCTAAAG
AGGATAATTCATAGAAAATTGAAAAAATGCGTTGTATTTGGAAGAACATC
ATCTGGAAAATCAAGTTTGATAAATGCCTTGTTAACAGAGGAAATTTTAC
CTACCAGCTGCGGGTCCACCTCGAATAGTTTCGTACAGATCAAGGCTAGT
TCATCTAAGAAGGAATATATAAGAATTAATAATGAAGTAAAAACGATTGA
GTCTTTACGTGAACTTACTAGTTTGTTATGTGAAGGTCACATCAAGGATG
GATCTCACGTTGATTTGTTCTACGATCCGGAGAAATGCAACCTTTTAAAA
GAAAACATTGAAATCATCGACACCCCCGGTATTGATTCTGACAGTAAATT
CGATAACTCAGTTGTGCAATATTTCAAAGATGTTAACCTGATAATATTAG
TGGTTAATTCAATTAGTGGAATAAGTCTTATTGAAAAGGAATTTTTGAGA
AAATTTGGAGGAAAATTTTCTAAATTACATTTATTGATTGTGTTCAATTT
ATGGGATTTTCCAGATAAAGCTAAAAATCGCGATGCGGTTCGTAAGCAGT
ATATGGAAAGTGCCACTAAATTATTGACCGATGAATTGGGATATTCCAAT
GAAAATGTGAGTAACAGAATATTCTTCTTTTCGGCATTTGAAAGAACCAA
GATTTTTTCATCAAAAGCTAAAACAGTGAGAAAAGATCCTCTTTTTAAAG
CTCGGAACGCGAGTTTTGAACAGTTTCTTATCACTCTAAAAGATGAACTG
GCAACTCTAGAACATAAAAAGGAATCTGATTGTTTAAATGAATTGTATTC
ATTGATATTGAAATTATTCAATAACAGTAATGCTGTTGATTTGATAATGA
ATAAAAGAAATCTAAATCATCAAATTTTAAAAGAATCAATCATTGAAACA
GACAAAATTTTAACGTTGGAATGTGTTACTAAAACATTCAATGAAATATA
CGAAGAATTTATTAATAAAGGAAATTGTTTATTCAATGAGTTTTTGAACA
ATGAAAAACATATCGATGTTACAAAAGTCAAAGAGGAAATAAATAGTAAG
CTGAAAGCATTGTTTCACGGTATTGCTAAATGTCACGAGGAACAGTTAAA
ATTATTTATCAACAAGCAAATCGGTGAATCACAAAACAAAAATTCAACTT
CCTGGATTTTGACAAAATTTTATTTTCCAAATTATTTTAATTTTAGTCAC
GAAATTCTAGATCATTCAGTGGAATTGAGTTTTTTTTACAACGAAATGGA
AAAAATCAATCAAACGATAAACAGCGGAAAGAAATTGACAACCATGTTAT
CAACATGCACAACTGTCGCTCATTTTGGATTTGGAGTCGCAACTGGTGGA
GTTCTTGGACTGACATTAGCAGCAGGAAGAATGGCGGTTGCTGGTTTGGT
TGGTTATGGATTGTCAAATGCAGTTATAGAAAATATGAAAACTCCGTTCG
AACATTTTTGGAAACATGATGCCAAGTCCATTCGTGATTATTTAGATAAA
CTGAAAATAAAATTCATATACAATTATACGGAATTTAAAAAAAGTTTATG
TGAAAATTTTGACAGTGAATTTTATGAAAATGGAATTGGCATCCAGAACA
AATTGAATGATATGAAAGTAAAAATACAAAAGTTCGAAAACAAAACGGAT
CTTCTTTCACATAAATCGTAAATAGAAATGATTTTATTGAAATTTAATTA
TTTCTTAATTTGAAATTTAATTGATAAAA

protein sequence of SMED30023988-orf-1

>SMED30023988-orf-1 ID=SMED30023988-orf-1|Name=SMED30023988-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=614bp
MSDDDNIYRELCGTLVDDIKKFENSCKELKKIFYPIMKENRKYQSIYNFD
EQAADLKRIIHRKLKKCVVFGRTSSGKSSLINALLTEEILPTSCGSTSNS
FVQIKASSSKKEYIRINNEVKTIESLRELTSLLCEGHIKDGSHVDLFYDP
EKCNLLKENIEIIDTPGIDSDSKFDNSVVQYFKDVNLIILVVNSISGISL
IEKEFLRKFGGKFSKLHLLIVFNLWDFPDKAKNRDAVRKQYMESATKLLT
DELGYSNENVSNRIFFFSAFERTKIFSSKAKTVRKDPLFKARNASFEQFL
ITLKDELATLEHKKESDCLNELYSLILKLFNNSNAVDLIMNKRNLNHQIL
KESIIETDKILTLECVTKTFNEIYEEFINKGNCLFNEFLNNEKHIDVTKV
KEEINSKLKALFHGIAKCHEEQLKLFINKQIGESQNKNSTSWILTKFYFP
NYFNFSHEILDHSVELSFFYNEMEKINQTINSGKKLTTMLSTCTTVAHFG
FGVATGGVLGLTLAAGRMAVAGLVGYGLSNAVIENMKTPFEHFWKHDAKS
IRDYLDKLKIKFIYNYTEFKKSLCENFDSEFYENGIGIQNKLNDMKVKIQ
KFENKTDLLSHKS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000099	neuron

Vocabulary: **INTERPRO**
Term	Definition
IPR027094	Mitofusin_fam
IPR027088	Mitofusin-1
IPR011528	NERD
IPR027417	P-loop_NTPase
IPR022812	Dynamin_SF
IPR030381	G_DYNAMIN_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005525	GTP binding
GO:0003924	GTPase activity

Vocabulary: **cellular component**
Term	Definition
GO:0005741	mitochondrial outer membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **biological process**
Term	Definition
GO:0008053	mitochondrial fusion

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR022812	Dynamin superfamily	PFAM	PF00350	Dynamin_N	coord: 68..208 e-value: 2.8E-21 score: 76.3
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 67..325 e-value: 2.8E-26 score: 94.5
IPR027094	Mitofusin family	PANTHER	PTHR10465	TRANSMEMBRANE GTPASE FZO1	coord: 40..281
IPR027088	Mitofusin-1	PANTHER	PTHR10465:SF2	MITOFUSIN-1	coord: 40..281
IPR030381	Dynamin-type guanine nucleotide-binding (G) domain	PROSITE	PS51718	G_DYNAMIN_2	coord: 61..311 score: 18.522
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 46..280

Main menu

Dynamin-type G domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

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