Netrin-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30023928 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11Note: Hover over icons to view figure legend
Homology
BLAST of Netrin-1 vs. Ensembl Human
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]) HSP 1 Score: 338.191 bits (866), Expect = 2.538e-104 Identity = 208/616 (33.77%), Postives = 315/616 (51.14%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKY-----YSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+G C P F+N A + V+S+CG P +Y R C +C+ + LTD N N TCW S Y Q N V ++++ K FEV YV+LQFCS P+S+ IYKS D G+ W+P+Q+YS C+K +N P PI + E C D + + + G ++ FS+ GR + L W+T TD+R+ SR H G + + S + + +Y VSDL VGGRC+C GH+ +C+ + D ++VCDC+HNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C GYYRD KP++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + T S + + + +S CK K K K + +V + ++++ + G +F + I V++ Q S I + + LWI ++ C CP I + YL+L + + ++ D ++++QWR +W RRL+KFQ + + KC+K
Sbjct: 45 NGHPRRCIPDFVNAAFGKDVRVSSTCGR-------PPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQS-ENYLQFPHN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP--HRAPITKQNEQEA--VCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRL-----------------HTFGDENEDDSELARDS-----YFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKI--PVAPPTTAASSVE----EPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHILKADKA-GDWWKFTVNIISVYK------QGTSRIRRGDQS--LWIRSRDIACKCPKIKPLKKYLLLGNAE--DSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. Ensembl Human
Match: NTN3 (netrin 3 [Source:HGNC Symbol;Acc:HGNC:8030]) HSP 1 Score: 292.738 bits (748), Expect = 1.554e-87 Identity = 186/625 (29.76%), Postives = 284/625 (45.44%), Query Frame = 3
Query: 711 LLLGFSFYFSVAISVLYENKQTTC-EFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFN-LPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFS----STIGRKMNDTLI--KWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSY----LILMKYKIYHHRHREELLLDSRTVMLQWRPSW 2549
LLL F+ A+S C + G C P +N A ++ +S+CG CD +S LT P + CW S + LN V +++ K FE+ +V+L+FCS P S+ + KS D+G+ W P ++S +C + LP P G E CF Q DG+ +L FS S G ++ + + W+T TD+R+ L+R S+ D RD+ + +S Y +DL VGGRC+C GH+++C+++ G+++CDC+H TEG DC +CK + D W+RA+ +C C CN H++ C+F +Y +G++SGGVC C+HNTAG CH+C G+YRD + LS AC+ C CH VG+ +C++ GQC CK+GV G C++C G+ Q+RS + PCVKT I S + + D S CKP + K + +V + V E G RF + + V+R E + + LW+ + C CP + GR Y L+ +++L WR +W
Sbjct: 8 LLLTAGTLFA-ALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCGRPA------------------TRACDASDPRRAHSPALLTSPGGTASPLCWRSE-SLPRAPLN-VTLTVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEA----LCFPAPLAQPDGS-----GLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTR----PSTAGDP-----------RDMEAVVPYS----------YAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAG-KTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKT--PIPGPTEDSSPVQPQDCD-----SHCKPARGSYRISLKKFCKKDYAVQVAVGARGEARGAWTRFPVAVLAVFRS--------GEERARRGSSALWVPAGDAACGCPRLLPGRRYLLLGGGPGAAAGGAGGRGPGLIAARGSLVLPWRDAW 561
BLAST of Netrin-1 vs. Ensembl Human
Match: LAMC1 (laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:6492]) HSP 1 Score: 217.624 bits (553), Expect = 1.898e-57 Identity = 141/445 (31.69%), Postives = 214/445 (48.09%), Query Frame = 3
Query: 792 GKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNH---VNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQ-TRSMLKPC 2096
G+ C P F+N A + T++CG P++ C + + C +CD + + + LTD NQ + T W S + G+ + +N+++ K F++ YV L+F + P+S IYK WIP+QYYS +C+ ++ + +L F GN+ FS+ GR + L +W+T TD+R+TL+R + G ++ N + K + YY +SD +VGGRC+C GH+++C+ N +VC+CKHNT G DC+KC F+D W RA+ + C C CN SQ C F+ +Y TG GG C CQ NT G C C ++R L ++ AC C C VGS + CD G+C CK GV+G KCD+C+ G+ T + +PC
Sbjct: 45 GRPQRCMPEFVNAAFNVTVVATNTCG-TPPEEYCVQTGV--TGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTML--AGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVA-------FSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRL-----------------NTFGDEVFN------DPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGH--GGHCTNCQDNTDGAHCERCRENFFR-----LGNNEACSSCHCSPVGSLST-QCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPC 445 HSP 2 Score: 68.1662 bits (165), Expect = 7.092e-11 Identity = 51/175 (29.14%), Postives = 73/175 (41.71%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLA---CKKCKCHA-VGSTNVNSCDKKLGQCF-CKEGVIGRKCDKCKIGYLQTRSMLKPCVK 2102
C C GHS C + VC+C+ NT G C+KC +G++ S C+ C C S K + VC C T G +C CD+GY+ D PL + C+ C+C + V +C++ G+C C G CD+CK G+ P K
Sbjct: 724 CACNGHSETC---DPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSS----DCQPCPCPGGSSCAVVPKTKEV--------VCTNCPTGTTGKRCELCDDGYFGD---PLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADK 880 HSP 3 Score: 68.1662 bits (165), Expect = 7.918e-11 Identity = 54/183 (29.51%), Postives = 81/183 (44.26%), Query Frame = 3
Query: 1548 SKVYYGVSDLSVGGRCQ---CYGHSNKCIINNDGNIVC-DCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGST-NVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRS 2081
S YYG S CQ C G S+ ++ +VC +C T G C+ C +G+ R + C+ CQC+ + + N + +G C KC +NTAG C C +G++ + P D CK C C+ G+ +SC+ GQC C V G+ C C G+ +S
Sbjct: 755 SDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVR--LCRLCQCSDN-----IDPNAVGNCNRLTG-ECLKCIYNTAGFYCDRCKDGFFGNPLAPNPAD-KCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQS 928 HSP 4 Score: 63.5438 bits (153), Expect = 1.762e-9 Identity = 47/141 (33.33%), Postives = 59/141 (41.84%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYL 2069
C C G C+ C G+ L P+S C C CN HS+ C E GVC C+ NTAG C C +GYY D T S D C+ C C S V K++ C G G++C+ C GY
Sbjct: 690 CTCPVGYGGQFCEMCLSGYR----RETPNLGPYSPCVLCACNGHSETCDPET-----------GVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSD--CQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYF 812 HSP 5 Score: 63.5438 bits (153), Expect = 2.141e-9 Identity = 59/214 (27.57%), Postives = 83/214 (38.79%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCK---HNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFC-----------------------------------------------KEGVIGRKCDKCKIGYLQTRS 2081
CQC + + + N + +C +NT G CD+CK+GF + NP CK C CNL+ K + + TGQ C +C + G C CD G+Y L C++C CHA+GSTN CD + GQC C +EG +G +CD+C+ Y RS
Sbjct: 828 CQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF----FGNPLAPNPADKCKACNCNLYGTM-KQQSSCNPVTGQ-----C-ECLPHVTGQDCGACDPGFYN-----LQSGQGCERCDCHALGSTN-GQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRS 1024
BLAST of Netrin-1 vs. Ensembl Human
Match: LAMC3 (laminin subunit gamma 3 [Source:HGNC Symbol;Acc:HGNC:6494]) HSP 1 Score: 201.06 bits (510), Expect = 4.200e-52 Identity = 131/433 (30.25%), Postives = 197/433 (45.50%), Query Frame = 3
Query: 792 GKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGP--VYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGR------KMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGY 2066
G+ C P F N A + +CG P+D CPH + C CD ++ LTD + + + W+ P + VNI++ K +E+ YV L+F + P+S IYK W P+Q+YS +CQK + P Q E + + F GN+ FS+ GR + + L +W+T T+L I+L D+++++ D DI + K + YY VSD SVGGRC+C GH+++C + G + C C+HNT G DC++C F D W R + C C C+ S+ C F++ ++ TG GG C C+ +TAG C C +Y W + C+ C C + GS ++ CD G C CK V G KCD+C G+
Sbjct: 30 GRPQRCLPVFENAAFGRLAQASHTCGSP-PEDFCPHVGAAGAGAH--CQRCDAADPQRHHNASYLTD-FHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGNVA-------FSTLEGRPSAYNFEESPGLQEWVTSTELLISL----DRLNTFGD-------------DIFK------DPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGH--GGRCHHCRDHTAGPHCERCQENFYH-WDP----RMPCQPCDCQSAGSLHLQ-CDDT-GTCACKPTVTGWKCDRCLPGF 419 HSP 2 Score: 73.9442 bits (180), Expect = 1.344e-12 Identity = 53/166 (31.93%), Postives = 77/166 (46.39%), Query Frame = 3
Query: 1590 RCQCYGHSNKCIINN----DGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQ-CNLHSQHCKFEK-NVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYL 2069
+CQC G+ + + N G+ + C HNT G C+ C+EGF+ S L P +C C+ H Q E+ TGQ S C + C C G++ L C+ CKCH +GS + C K GQC C+ GV G+ CD+C++G+
Sbjct: 809 QCQCSGNVDPNAVGNCDPLSGHCL-RCLHNTTGDHCEHCQEGFY------GSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCS------CLPHVTARDCSRCYPGFFD-----LQPGRGCRSCKCHPLGSQE-DQCHPKTGQCTCRPGVTGQACDRCQLGFF 955 HSP 3 Score: 66.2402 bits (160), Expect = 3.009e-10 Identity = 47/179 (26.26%), Postives = 69/179 (38.55%), Query Frame = 3
Query: 1602 YGHSNKCIINNDGNI-----VCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFS-----CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHA-VGSTNVNSCDKKLGQCF-CKEGVIGRKCDKCKIGYLQTRSMLKPCVK 2102
Y C N G +C C H+TEG C++C GF+ NPF+ C+ C C S ++ + VC C G +C CD+G++ D H C +C+C V V +CD G C C G C+ C+ G+ + +P K
Sbjct: 701 YASCVPCTCNQHGTCDPNTGICVCSHHTEGPSCERCLPGFYG---------NPFAGQADDCQPCPCPGQSACTTIPESREV--------VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADK 862 HSP 4 Score: 57.3806 bits (137), Expect = 1.661e-7 Identity = 46/165 (27.88%), Postives = 70/165 (42.42%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCN-LHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTR--SMLKPCVKTYDIIESSQTK 2135
C C + DC +C GF DLQ R C+ C+C+ L SQ E + KTGQ + C+ G C C G++ K C+ C+C +G+ + C + G C C+ G G KCD+C + T + + C Y +++ K
Sbjct: 887 CSCLPHVTARDCSRCYPGFFDLQPGRG-------CRSCKCHPLGSQ----EDQCHPKTGQCT------CRPGVTGQACDRCQLGFFGFSIK------GCRACRCSPLGAASAQ-CHEN-GTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYALVKEEAAK 1026
BLAST of Netrin-1 vs. Ensembl Human
Match: NTN5 (netrin 5 [Source:HGNC Symbol;Acc:HGNC:25208]) HSP 1 Score: 184.882 bits (468), Expect = 1.214e-49 Identity = 99/338 (29.29%), Postives = 164/338 (48.52%), Query Frame = 3
Query: 1587 GRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCE 2600
GRCQC+GH+ +C C+H+T G C+ C+ D W A+ +P C C CN H++ C+F ++ +G +SGGVC +C+H+TAG CH+C G++RD ++P+ AC+ C+CH +G+T +C++ GQC CK GV G C++C GY Q+RS PC + I + T + Y P ++ C D + + + + V+ S+ R +++ V++ + +Q + Q+ W+ ++ C C + G YL+L L+LD + L WRP W R L++ Q + C
Sbjct: 155 GRCQCHGHAARCAARARPPRC-HCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATG-GTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQR----IPEATTTLATTPGAYSSDPQCQNYCNMSDTRVHMSLRRYCQQDHVLRAQVLASEAAGPAWQRLAVRVLAVYK---QRAQPVRRGDQDA-----WVPRADLTCGCLRLQPGTDYLLLG--SAVGDPDPTRLILDRHGLALPWRPRWARPLKRLQQEERAGGCR 476
BLAST of Netrin-1 vs. Ensembl Celegans
Match: unc-6 (Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34710]) HSP 1 Score: 332.413 bits (851), Expect = 1.822e-102 Identity = 196/653 (30.02%), Postives = 315/653 (48.24%), Query Frame = 3
Query: 696 LFNSILLLGFSFYFSVAIS--------VLYENKQTTCEFH-GKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKT---YDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFLQKK 2618
+ S+L + YF + I+ + C H G+ C P FIN A + + +CG PD C + C CD + LTD + N TCW S P + +V+++++ K FE+ YV++ FCS LPDS+ +YKS D GK W P+Q+YS C++ F P + I + E C + GN + S + + L W+T TD+++ SR + + + +N +D+ + +Y + +L+VGGRC+C GH+++CI + G CDCKHNT G +C+ CK +D W RA+ + SC C CN H++ C+F+ ++ +G +SGGVC C+HNTAG CH C G+ RD + P++H ACK C CH VGS SC++ GQC CK GV G C++C GY Q+RS + PC+K D I SS +++ D SK +P ++ K C D V+ S+E+ ++++ ++ V++ + + ++ LWIS + V C CP + +GR YL+L K H R+ L+++ +TV+++W ++ +F K +C + +
Sbjct: 1 MITSVLRYVLALYFCMGIAHGAYFSQFSMRAPDHDPCHDHTGRPVRCVPEFINAAFGKPVIASDTCGTNRPDKYCTVKEGPDGIIREQCDTCDARNHFQSHPASLLTDLNSIGNMTCWVSTPSLSPQ---NVSLTLSLGKKFELTYVSMHFCSRLPDSMALYKSADFGKTWTPFQFYSSECRRIFGRDP--DVSITKSNEQEA--VCTASHIMGPGGNRVAFPFLENRPSAQNFENSPVLQDWVTATDIKVVFSRLSPDQAELYGLS-----------NDVNSYGNETDDEVKQRYFYSMGELAVGGRCKCNGHASRCIFDKMGRYTCDCKHNTAGTECEMCKPFHYDRPWGRATANSANSCVACNCNQHAKRCRFDAELFRLSGNRSGGVCLNCRHNTAGRNCHLCKPGFVRDTSLPMTHRKACKSCGCHPVGSLG-KSCNQSSGQCVCKPGVTGTTCNRCAKGYQQSRSTVTPCIKIPTKADFIGSSHSEEQDQCSKCRIVPKRLNQKKFCKR-------------DHAVQMVVVSREMVDGWAKYKIVVESVFKRGTE--------NMQRGETSLWISPQGVICKCPKLRVGRRYLLLGKNDSDH--ERDGLMVNPQTVLVEWEDDIMDKVLRFSKKDKLGQCPEITSHR 611
BLAST of Netrin-1 vs. Ensembl Celegans
Match: unc-6 (Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34710]) HSP 1 Score: 332.413 bits (851), Expect = 1.822e-102 Identity = 196/653 (30.02%), Postives = 315/653 (48.24%), Query Frame = 3
Query: 696 LFNSILLLGFSFYFSVAIS--------VLYENKQTTCEFH-GKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKT---YDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFLQKK 2618
+ S+L + YF + I+ + C H G+ C P FIN A + + +CG PD C + C CD + LTD + N TCW S P + +V+++++ K FE+ YV++ FCS LPDS+ +YKS D GK W P+Q+YS C++ F P + I + E C + GN + S + + L W+T TD+++ SR + + + +N +D+ + +Y + +L+VGGRC+C GH+++CI + G CDCKHNT G +C+ CK +D W RA+ + SC C CN H++ C+F+ ++ +G +SGGVC C+HNTAG CH C G+ RD + P++H ACK C CH VGS SC++ GQC CK GV G C++C GY Q+RS + PC+K D I SS +++ D SK +P ++ K C D V+ S+E+ ++++ ++ V++ + + ++ LWIS + V C CP + +GR YL+L K H R+ L+++ +TV+++W ++ +F K +C + +
Sbjct: 1 MITSVLRYVLALYFCMGIAHGAYFSQFSMRAPDHDPCHDHTGRPVRCVPEFINAAFGKPVIASDTCGTNRPDKYCTVKEGPDGIIREQCDTCDARNHFQSHPASLLTDLNSIGNMTCWVSTPSLSPQ---NVSLTLSLGKKFELTYVSMHFCSRLPDSMALYKSADFGKTWTPFQFYSSECRRIFGRDP--DVSITKSNEQEA--VCTASHIMGPGGNRVAFPFLENRPSAQNFENSPVLQDWVTATDIKVVFSRLSPDQAELYGLS-----------NDVNSYGNETDDEVKQRYFYSMGELAVGGRCKCNGHASRCIFDKMGRYTCDCKHNTAGTECEMCKPFHYDRPWGRATANSANSCVACNCNQHAKRCRFDAELFRLSGNRSGGVCLNCRHNTAGRNCHLCKPGFVRDTSLPMTHRKACKSCGCHPVGSLG-KSCNQSSGQCVCKPGVTGTTCNRCAKGYQQSRSTVTPCIKIPTKADFIGSSHSEEQDQCSKCRIVPKRLNQKKFCKR-------------DHAVQMVVVSREMVDGWAKYKIVVESVFKRGTE--------NMQRGETSLWISPQGVICKCPKLRVGRRYLLLGKNDSDH--ERDGLMVNPQTVLVEWEDDIMDKVLRFSKKDKLGQCPEITSHR 611
BLAST of Netrin-1 vs. Ensembl Celegans
Match: lam-2 (Laminin-like protein lam-2 [Source:UniProtKB/Swiss-Prot;Acc:Q18823]) HSP 1 Score: 197.978 bits (502), Expect = 1.525e-51 Identity = 133/434 (30.65%), Postives = 210/434 (48.39%), Query Frame = 3
Query: 807 CTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNH---VNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTC-FDLNQKQKDGNLGQAESILPFSSTIGR------KMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCI----INNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGY 2066
C P F+N A ++ VT++CG P C + C CD+ + + K LTD N N+ W+ Q G + N+++ K+F++ YV L+F S P+S TIYK +W PWQ+YS +C+ + L + PI G E + T F GN+ FS+ GR + ++ L KW+T + +RI+L+R M+++ D F + + + YY +SD +VGGRC+C GH+++C+ ++ + +VC C+HNT+GADC++C ++D W + + C C C+ S C F++ ++ +TG GG C CQ NT G C C W +P + C C C+ +GS + CD + G+C CK GV GR CD+C G+
Sbjct: 51 CVPDFVNAAFNLEVQVTNTCGTKRPTKFCVQSGHTGQRSV--CETCDDRHEGFSHPAKYLTD-FNVGNNETWWQSDTM-QEGQQYPTTTNLTLVLGKSFDITYVRLKFISPRPESFTIYKKTHTDSEWEPWQFYSGSCRATYGL--SDRAPILPGNEATAQCTKEFSDISPITGGNIA-------FSTLEGRPSAHAFEESEVLQKWVTASAIRISLNR----MNTFGD------------------EVFK-DPQVLRSYYYAISDFAVGGRCKCNGHASECVGSSSVDGENRLVCRCEHNTQGADCNECLPFYNDRPWRSGTSVEANECIACNCSQLSNRCYFDQQLFEETGH--GGHCIDCQGNTQGVHCEQC---IANHWRRPGEN--YCVACGCNEIGSLST-QCDNE-GKCQCKPGVTGRFCDQCLDGF 439 HSP 2 Score: 73.1738 bits (178), Expect = 8.161e-13 Identity = 50/158 (31.65%), Postives = 73/158 (46.20%), Query Frame = 3
Query: 1590 RCQCYGHSNKCIINNDGNIVCDCKH---NTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKC 2054
C C G+++ I N I +CK NT G +C+ CK G+ W A +C+ C C ++ Q+ G C N G QC C +G+Y ++ L C++C C +GS N+CD GQC CK GV G++CD+C
Sbjct: 834 ECACSGNTDPNSIGNCDKITGECKKCIFNTHGFNCENCKPGY----WGDALIEPKGNCQSCGCFAAGTRRPNNDYTLLECNQQDGQC--DCLPNVIGIQCDQCAHGFYN-----ITSGLGCQECNCDPLGSEG-NTCDVNTGQCQCKPGVTGQRCDRC 979 HSP 3 Score: 65.855 bits (159), Expect = 1.501e-10 Identity = 50/153 (32.68%), Postives = 69/153 (45.10%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLN-PFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVK 2102
C+C G C+ C+ GF R +K PF+ C +C C+ HS C+ E G C C+HNTAG+ C C GYY D + D C+KC C G +++ D + C G GR+CD+C GY CV+
Sbjct: 702 CECLPGFVGQFCESCESGFR-----RETKFGGPFNHCIKCDCHNHSNSCEAES-----------GSC-ICEHNTAGDTCERCARGYYGDALQGTEED--CQKCPCPNDGPCILHA-DGDVICTECPNGYTGRRCDECSDGYFGNPKDGTECVE 834 HSP 4 Score: 62.003 bits (149), Expect = 2.148e-9 Identity = 59/217 (27.19%), Postives = 85/217 (39.17%), Query Frame = 3
Query: 1590 RCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCN------LHSQH---CKFEKNVYM---------------KTG--------------------QKSGGVCRKCQHNTAGNQCHFCDNGYYRD-WTKPLSHDLACKKCKCHAVGSTNVNS------CDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSML 2087
+C C+ HSN C + C C+HNT G C++C G++ + + C++C C LH+ C N Y K G K G C+KC NT G C C GY+ D +P + C+ C C A G+ N+ C+++ GQC C VIG +CD+C G+ S L
Sbjct: 735 KCDCHNHSNSCEAESGS---CICEHNTAGDTCERCARGYYGDALQGTEE----DCQKCPCPNDGPCILHADGDVICTECPNGYTGRRCDECSDGYFGNPKDGTECVECACSGNTDPNSIGNCDKITGECKKCIFNTHGFNCENCKPGYWGDALIEPKGN---CQSCGCFAAGTRRPNNDYTLLECNQQDGQCDCLPNVIGIQCDQCAHGFYNITSGL 941
BLAST of Netrin-1 vs. Ensembl Celegans
Match: lam-3 (LAMinin related. See also lmb; Laminin alpha chain [Source:UniProtKB/TrEMBL;Acc:G5ECE3]) HSP 1 Score: 163.31 bits (412), Expect = 1.900e-40 Identity = 128/457 (28.01%), Postives = 211/457 (46.17%), Query Frame = 3
Query: 813 PPFINIAQRAKITVTSSCGEILPDDICPHWKYY-----SSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFC-SELPDSITIYKSHDNGKKWIPWQYYS---KNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRK-MNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINN-DGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHC----KFEKNVYMKTGQ---KSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSH--DLACKKCKCHAVGSTNVNSC---------DKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPC 2096
P N+A + IT T +CG+ ++ C ++ ++ C ICD + + + I+ D ++ W S + N VNI+I ++ ++V Y+ L+ S P + + KS D G+ + PWQYY+ C + F +P T P + ++ K L E + S GR +T ++ T R R + D L+ I+N + S++ + +Y +SD+S+GG+C CYGH+ C + G C+C+HNT G C++C F+ L W+ + +P C++CQC H+ C + ++N + T + + GG C +C HNT G C C +GYYR LSH + AC+ C+C VGS + ++C +K G C CK G GR+C++C GY + +PC
Sbjct: 50 PNIFNLATNSLITATDTCGQYTAEEYCKLVEHVLLRKTTNTQSPQCDICDANNVHKRHPIEYAIDGTRRW----WQSPSLANGLRFEKVNITIDLRQEYQVAYIILKMGNSPRPGTWVLEKSLD-GEYYEPWQYYAMQDAECMRQFGIPATTGVP-----RFQKEDEVHCTSEYSKITPLENGE--IHTSLVNGRPGAENTSLELQKFTRARFVRLRLISPRTLNAD-----LM-------IINKKSDSLDKSVTMRYFYSISDISIGGQCICYGHAESCPSDPVTGQFKCECRHNTCGESCNRCCPLFNQLPWKPGTNSHPNVCQQCQCFNHAHSCVYDDELDRNKWSITPEGVYEGGGRCLECAHNTEGFNCERCKDGYYR--PSGLSHYREDACRTCECDPVGSVS-DACVRDDQSAENGQKPGDCICKPGFGGRRCERCAPGY-RNHPTCEPC 478 HSP 2 Score: 77.7962 bits (190), Expect = 3.167e-14 Identity = 54/155 (34.84%), Postives = 73/155 (47.10%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCK 2057
C C+GHS C N D ++ DC+HNT G C+ C G+ E + +C +C C L ++ + V + G+ G VC C+ G C C GYY D P C C CH GS + +C+ GQC CK GV GR C C+
Sbjct: 1540 CSCHGHSQTC--NPDTSVCTDCEHNTFGDFCEHCLPGYIGDAREGGAN----ACTKCACPL-VENSFSDSCVAVDHGR--GYVCNSCKPGYTGQYCETCVAGYYGD---PQHIGGTCSPCDCHPDGSLH-GACNPLSGQCECKPGVTGRTCSMCQ 1681 HSP 3 Score: 72.4034 bits (176), Expect = 1.718e-12 Identity = 53/182 (29.12%), Postives = 84/182 (46.15%), Query Frame = 3
Query: 1590 RCQCYGHSNKCIINND----------------GNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPF---SCKRCQCNLH---SQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYL 2069
+CQC+ H++ C+ +++ G +C HNTEG +C++CK+G++ R S L+ + +C+ C+C+ S C + + GQK G C+ G +C C GY T C+ C C+ GS N ++CD C CK V G CD+CK G +
Sbjct: 352 QCQCFNHAHSCVYDDELDRNKWSITPEGVYEGGGRCLECAHNTEGFNCERCKDGYY-----RPSGLSHYREDACRTCECDPVGSVSDAC-VRDDQSAENGQKPGDCI--CKPGFGGRRCERCAPGYRNHPT--------CEPCPCNRAGSVNFDTCDG--ASCQCKANVEGIYCDRCKAGTI 515 HSP 4 Score: 64.6994 bits (156), Expect = 3.883e-10 Identity = 50/175 (28.57%), Postives = 72/175 (41.14%), Query Frame = 3
Query: 1557 YYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRS 2081
++G + L C C+ ++ N C+CK N GA CD+CKE D++ C C CN + + G C C+ G QC C Y+ ++T D C+ C C+ GS CD+ G+C C+E V G C+KC GY S
Sbjct: 929 HWGNAQLHTCKPCGCHTQGAVNPQCSEENGECECKENYIGAQCDRCKENHGDVE---------NGCPACDCN--------DTGSIGSDCDQVSGQC-NCKQGVFGKQCDQCRPSYF-NFT-----DAGCQFCHCNIYGSIEDGKCDQTTGKCECRENVEGTMCEKCADGYFNITS 1079 HSP 5 Score: 63.929 bits (154), Expect = 6.077e-10 Identity = 41/137 (29.93%), Postives = 63/137 (45.99%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQ--KSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKC 2054
C+CK G CD+C+ + + C+ C CN++ ++ G+ ++ G C +C+ N G C C +GY+ ++ C+ C C GS +V SC+ GQC CK GV G KCD C
Sbjct: 1007 CNCKQGVFGKQCDQCRPSYFNF--------TDAGCQFCHCNIYGS---------IEDGKCDQTTGKC-ECRENVEGTMCEKCADGYFN-----ITSGDGCEDCGCDPTGSEDV-SCNLVTGQCVCKPGVTGLKCDSC 1119 HSP 6 Score: 62.003 bits (149), Expect = 2.196e-9 Identity = 51/178 (28.65%), Postives = 83/178 (46.63%), Query Frame = 3
Query: 1557 YYGVSDLSVGGRCQ---CYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQC-----NLHSQHCKFEKNVYMKTGQKSGG-VCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHA-VGSTNVNSCDKKLGQCF-CKEGVIGRKCDKCK 2057
Y V++ GGRC+ C+G+S +C + +C+HNT G+ C+ CK G H R +L +C++C+C N + + E V VC C GN+C +C +G++ D PL+ C +C C+ + + +CD + G+C C G C+ CK
Sbjct: 759 YRRVNNQLYGGRCEKCDCHGNSEEC--DPFTGECLNCRHNTTGSRCELCKPG-HVGNPSRGGELG--ACEQCECPSLDLNPNPECISTELAVLGSVASNEDNYVCINCPLGYEGNKCEYCSDGFFED---PLTG--KCIECTCNGNIDPMGIGNCDSETGKCLKCIGHTTGDSCESCK 926 HSP 7 Score: 52.7582 bits (125), Expect = 1.545e-6 Identity = 47/170 (27.65%), Postives = 68/170 (40.00%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASK---LNPFSCKRCQCNLHSQHCKFEKNV------------YMKTGQ---------KSGGVCRK------CQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYL 2069
C+C+ N EG C+KC +G+ ++ + +P + CNL + C + V Y T + G VC C NT G C C + D+ PL+ CK C C +GS + C+ GQC CK +G KCD C G+
Sbjct: 1056 CECRENVEGTMCEKCADGYFNITSGDGCEDCGCDPTGSEDVSCNLVTGQCVCKPGVTGLKCDSCLPNFYGLTSEGCTECEPCPAPGQVCDPIDGSCVCPPNTVGEMCENCTTNAW-DY-HPLN---GCKLCDCSDIGS-DGGMCNTFTGQCKCKAAYVGLKCDLCTHGFF 1219
BLAST of Netrin-1 vs. Ensembl Celegans
Match: lam-1 (LAMinin related. See also lmb [Source:UniProtKB/TrEMBL;Acc:V6CIX7]) HSP 1 Score: 162.54 bits (410), Expect = 2.642e-40 Identity = 111/378 (29.37%), Postives = 176/378 (46.56%), Query Frame = 3
Query: 1041 NQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKY---FLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCI----------INNDGNIV---CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKK--------LGQCFCKEGVIGRKCDKCKIGYLQ-TRSMLKPCV 2099
+++G +V+IS + F ++ + F S P ++ I +S D GK W ++Y++ +C +F P E P ++ + + Q + P ST G I + I+ +T + + D++S+ F H G D+L+ + K YY + ++ V G C CYGH+++CI + +IV C+C HNTEG +C+KCK ++DL W A C++C CN H+ C F++ VY +G SGGVC C HNT G C C +YRD + + C C+C GS N C+ + G+C+CK V G +CD+CK GY T + + CV
Sbjct: 118 SENGAQNVSISFDLEAEFHFTHLIMTFKSFRPAAMIIERSADFGKTWQVYRYFAYDCDSSF--PGIPEGPPKKHTDVICT---------------SQYSDVAP--STGGE------IVYKVISPHIVTENPYADEISTLLKITNLRFNFTKLHTLGDDLLDYRP-----EIDEKYYYAIYEIVVRGSCSCYGHASRCIPIDPHVSPNTVMERADIVHGRCECMHNTEGLNCEKCKAFYNDLPWRPAIGDEKNECRQCNCNRHALRCHFDRAVYESSGFVSGGVCDDCMHNTQGKNCEQCKPFFYRDPRRTIDDPHVCLPCECDKAGSQNKGICEGEEDAERGLVAGKCYCKTNVDGNRCDRCKNGYWNLTETNVDGCV 465 HSP 2 Score: 82.8037 bits (203), Expect = 1.007e-15 Identity = 58/181 (32.04%), Postives = 88/181 (48.62%), Query Frame = 3
Query: 1557 YYGVSDLSVGGRCQ----------CYGHSNKCIINNDGN----IVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNV-NSCDKKLGQCFCKEGVIGRKCDKC 2054
YYG L VG C+ Y H++ C + N GN IVC+CK +G C +C + W ++ +C+RC CN + E + TG+ C KC H+T G QC C +GYY D + C++C C+ +G+ + +CD+ GQC C + +IG +CD+C
Sbjct: 909 YYGDPRLGVGIPCKPCPCPGGPTSGYQHADTCYLRNSGNNTQDIVCNCKSGYQGERCGECAQN----HWGSPREVGG-TCERCDCNGNIDM-AMEGSCDAATGE-----CLKCLHHTEGAQCEHCVDGYYGD-----AKLKTCQRCVCNELGTNSTKGACDRVSGQCPCHDNIIGMQCDQC 1073 HSP 3 Score: 56.225 bits (134), Expect = 1.137e-7 Identity = 47/135 (34.81%), Postives = 62/135 (45.93%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTG-QKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLS-HDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCD 2048
C CK N +G CD+CK G+ +L ++ N C C CNL Y G K G+C C+ G C C +Y LS H CK C C GS + N+C+ GQC C+EG GR+C+
Sbjct: 435 CYCKTNVDGNRCDRCKNGYWNL-----TETNVDGCVACTCNLLG--------TYNNEGCDKYTGMC-TCKRLVTGENCDQCLPEHY-----GLSEHVDGCKACDCDIGGSYD-NTCEITTGQCKCREGFSGRRCE 549 HSP 4 Score: 53.9138 bits (128), Expect = 7.510e-7 Identity = 47/186 (25.27%), Postives = 78/186 (41.94%), Query Frame = 3
Query: 1557 YYGVSDLSVGGRCQC--YGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTY 2108
YYG + L RC C G ++ + + C C N G CD+C E +L + C+ C C+ + E +++ G +C+ G +C C++ Y+ D T P C +C+C+ GS ++ C + G C C+ G G C++C GY PC + +
Sbjct: 1026 YYGDAKLKTCQRCVCNELGTNSTKGACDRVSGQCPCHDNIIGMQCDQCAENHFNL-------ASGAGCEACGCDSNGVVLNHEGVPHLQCNIFDGQC--QCKPGRGGRKCDQCEDLYWGDPTTPD----GCHRCECNPTGSKSLQ-CHRNNGTCECQAGSGGALCNECARGYTGQWPYCNPCGECF 1197 HSP 5 Score: 51.2174 bits (121), Expect = 4.791e-6 Identity = 73/362 (20.17%), Postives = 130/362 (35.91%), Query Frame = 3
Query: 1077 AFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYY--------SKNCQKAFNLPPTQEFPI------------------QEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRI--TLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYY---GVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCF-CKEGVIGRKCDKCKIGY 2066
F + E + + E+ + HD + + W+ ++ + PP+ +F I + G++Y L N+K+ + + P + D+++ ++L I +R + ++ Y Y L L++S F + + Y + L+ C C + I N C+CK N G CD+C G + P CK+C C+ + ++GQ VCR + G QC+ C G+ W P C+ C+C+ + N CD+ G C C++ G CD+C+ GY
Sbjct: 595 GFAQAVEGTIITVNPIVEVSQKYNVIIRHDGARDPVGWENIQITVVRPEAEGDGSCSDAPPSDDFLIARIYPGSRYIEVQPAICLEAGVQYELR---IQFNEKRGNSH--------PQERAAANILIDSILLAPPTSELHIFQGSARAEQHLTEYNRYQCRHL--------ALSLSLFKDQRNEVCERYVCPIAAALLNKTSECNCDATGSVSGICNVQGGQCECKPNVVGRRCDQCAIGTY--------GFGPSGCKKCDCDAVG---SLGNDCDKQSGQ---CVCR--EKGIYGRQCNQCQPGF---WGFP-----ECRTCQCN----DHANICDQSSGACIECRDLTTGHYCDRCQDGY 909
BLAST of Netrin-1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0308337) HSP 1 Score: 283.108 bits (723), Expect = 1.903e-83 Identity = 161/452 (35.62%), Postives = 231/452 (51.11%), Query Frame = 3
Query: 807 CTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFC--SELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMN------DTLIKWITITDLRIT---LSRFDDQM--------SSYFDYGKYFL-LKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVK 2102
C P F+N A A + +S+CG C + +H R C CD + +SLTD N N TCW S PV ++V ++++ K FE+ YV LQ C + PDS+ IYKS D+G W P+Q++S C++ F P Q G C D+ + S + FS+ GR + L W+T TD+R+ L R D Q ++ GKY + L + + + + S S ++Y +SD SVGGRC+C GH++KC + G + C+C HNT G DC++CK D W RA+ CK C CN H++ C+F ++ + SGGVC+ C+H+T G CH C G+YRD TKPL+H CK C CH +GS+ C+ GQC CK+GV G C++C GY Q+RS + PC+K
Sbjct: 50 CIPDFVNAAYDAPVVASSTCGSSGAQRYCEY-----QDHERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGSG--DNVTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQS----TGRHNEHEARCSDVTRP--------LVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGSSG-KICNSTSGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIK 481
BLAST of Netrin-1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0073942) HSP 1 Score: 283.493 bits (724), Expect = 5.798e-83 Identity = 161/452 (35.62%), Postives = 231/452 (51.11%), Query Frame = 3
Query: 807 CTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFC--SELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMN------DTLIKWITITDLRIT---LSRFDDQM--------SSYFDYGKYFL-LKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVK 2102
C P F+N A A + +S+CG C + +H R C CD + +SLTD N N TCW S PV ++V ++++ K FE+ YV LQ C + PDS+ IYKS D+G W P+Q++S C++ F P Q G C D+ + S + FS+ GR + L W+T TD+R+ L R D Q ++ GKY + L + + + + S S ++Y +SD SVGGRC+C GH++KC + G + C+C HNT G DC++CK D W RA+ CK C CN H++ C+F ++ + SGGVC+ C+H+T G CH C G+YRD TKPL+H CK C CH +GS+ C+ GQC CK+GV G C++C GY Q+RS + PC+K
Sbjct: 50 CIPDFVNAAYDAPVVASSTCGSSGAQRYCEY-----QDHERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGSG--DNVTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQS----TGRHNEHEARCSDVTRP--------LVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGSSG-KICNSTSGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIK 481
BLAST of Netrin-1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0346088) HSP 1 Score: 283.493 bits (724), Expect = 5.798e-83 Identity = 161/452 (35.62%), Postives = 231/452 (51.11%), Query Frame = 3
Query: 807 CTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFC--SELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMN------DTLIKWITITDLRIT---LSRFDDQM--------SSYFDYGKYFL-LKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVK 2102
C P F+N A A + +S+CG C + +H R C CD + +SLTD N N TCW S PV ++V ++++ K FE+ YV LQ C + PDS+ IYKS D+G W P+Q++S C++ F P Q G C D+ + S + FS+ GR + L W+T TD+R+ L R D Q ++ GKY + L + + + + S S ++Y +SD SVGGRC+C GH++KC + G + C+C HNT G DC++CK D W RA+ CK C CN H++ C+F ++ + SGGVC+ C+H+T G CH C G+YRD TKPL+H CK C CH +GS+ C+ GQC CK+GV G C++C GY Q+RS + PC+K
Sbjct: 50 CIPDFVNAAYDAPVVASSTCGSSGAQRYCEY-----QDHERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGSG--DNVTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQS----TGRHNEHEARCSDVTRP--------LVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGSSG-KICNSTSGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIK 481
BLAST of Netrin-1 vs. Ensembl Fly
Match: LanB2 (gene:FBgn0267348 transcript:FBtr0345031) HSP 1 Score: 214.542 bits (545), Expect = 8.718e-57 Identity = 138/437 (31.58%), Postives = 225/437 (51.49%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYN--QHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSR---FDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCI----INNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQ 2072
+G+ C P FIN A + +I T++CGE + C + + NH ++C C + N + LTD + + T W S ++ QH N+VN+++ K++++ YV + F S P+S TIYK WIP+Q+YS C+ ++LP ++ EG ++L + + +DG + + ++ S I + + L +W+T TD+RITL R F D++ +G +LK +Y +SD++VG RC+C GH++KC+ ++ + +VC+C+HNT+G DCD+C ++DL+W+R++ CK C CN + C F+ N++ +TG GG C C+ N G C C +Y + D C C C VGS ++ C+ G+C CK GV G KCD+C Y Q
Sbjct: 61 YGRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFC--IQTMNQNH-KNCEFCKYNDHNPSF----LTDLHDPQSPTWWQSETMFEGIQH-PNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAHALCTSEYSDISPLRDGEIAFS-TLEGRPSGINFERSGELQEWVTATDIRITLDRLNTFGDEL-----FGDSQVLK---------------------SYFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRTGH--GGHCLDCRENRDGPNCERCKENFY------MRDDGYCVNCACDPVGSRSL-QCNSH-GKCQCKPGVTGDKCDRCDNNYYQ 452 HSP 2 Score: 82.8037 bits (203), Expect = 1.304e-15 Identity = 66/217 (30.41%), Postives = 98/217 (45.16%), Query Frame = 3
Query: 1464 YGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGG------RCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLA-CKKCKCHAVGST----NVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRS 2081
+G + GR I +T N +K +YG + +GG RC C IN D I +C G+ C++C +GF ++ +CK C CN + + N + ++ G C KC HNTAG C C +G++ D PL+ C +C C+ G+ ++ CD+ GQC CK VIGR C +C+ GY RS
Sbjct: 747 HGHADICDSETGRCICQHNTHGDNCDQCAKGFYGNA---LGGTPNDCKRCPCPNDGACLQINEDTVICTECPKGYFGSRCEQCSDGFFGDPTGLLGEVQ--TCKSCDCNGN-----VDPNA-VGNCNRTTGECLKCIHNTAGEHCDQCLSGHFGD---PLALPHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGECQPGYFNIRS 949 HSP 3 Score: 62.7734 bits (151), Expect = 1.494e-9 Identity = 46/158 (29.11%), Postives = 72/158 (45.57%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCK---HNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCK 2057
C C G+ + + N +C HNT G CD+C G + L C RC C + + ++ + Q +G +C+ N G C C GY+ + C+ C C VGS N ++CD+ GQC C+ GV+G++CD+C+
Sbjct: 847 CDCNGNVDPNAVGNCNRTTGECLKCIHNTAGEHCDQCLSG----HFGDPLALPHGRCDRCSC--YEAGTEQDEQSITRCDQVTGQC--QCKPNVIGRDCGECQPGYFN-----IRSGNGCENCLCDPVGSYN-STCDRYSGQCHCRPGVMGQRCDQCE 990 HSP 4 Score: 55.0694 bits (131), Expect = 3.351e-7 Identity = 43/159 (27.04%), Postives = 68/159 (42.77%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESS 2126
C CK N G DC +C+ G+ +++ C+ C C+ Y T + G C C+ G +C C+N +Y ++ CK C+C GS CD+ GQC C + V GR+CD+CK C Y++++ +
Sbjct: 926 CQCKPNVIGRDCGECQPGYFNIRSGNG-------CENCLCD--------PVGSYNSTCDRYSGQCH-CRPGVMGQRCDQCENYFYGFSSE------GCKPCECDESGSKGF-QCDQN-GQCPCNDNVEGRRCDRCKENKYDRHRGCIDCPDCYNLVQDA 1060
BLAST of Netrin-1 vs. Ensembl Fly
Match: LanB2 (gene:FBgn0267348 transcript:FBtr0076382) HSP 1 Score: 214.542 bits (545), Expect = 8.718e-57 Identity = 138/437 (31.58%), Postives = 225/437 (51.49%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYN--QHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSR---FDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCI----INNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQ 2072
+G+ C P FIN A + +I T++CGE + C + + NH ++C C + N + LTD + + T W S ++ QH N+VN+++ K++++ YV + F S P+S TIYK WIP+Q+YS C+ ++LP ++ EG ++L + + +DG + + ++ S I + + L +W+T TD+RITL R F D++ +G +LK +Y +SD++VG RC+C GH++KC+ ++ + +VC+C+HNT+G DCD+C ++DL+W+R++ CK C CN + C F+ N++ +TG GG C C+ N G C C +Y + D C C C VGS ++ C+ G+C CK GV G KCD+C Y Q
Sbjct: 61 YGRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFC--IQTMNQNH-KNCEFCKYNDHNPSF----LTDLHDPQSPTWWQSETMFEGIQH-PNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAHALCTSEYSDISPLRDGEIAFS-TLEGRPSGINFERSGELQEWVTATDIRITLDRLNTFGDEL-----FGDSQVLK---------------------SYFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRTGH--GGHCLDCRENRDGPNCERCKENFY------MRDDGYCVNCACDPVGSRSL-QCNSH-GKCQCKPGVTGDKCDRCDNNYYQ 452 HSP 2 Score: 82.8037 bits (203), Expect = 1.304e-15 Identity = 66/217 (30.41%), Postives = 98/217 (45.16%), Query Frame = 3
Query: 1464 YGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGG------RCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLA-CKKCKCHAVGST----NVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRS 2081
+G + GR I +T N +K +YG + +GG RC C IN D I +C G+ C++C +GF ++ +CK C CN + + N + ++ G C KC HNTAG C C +G++ D PL+ C +C C+ G+ ++ CD+ GQC CK VIGR C +C+ GY RS
Sbjct: 747 HGHADICDSETGRCICQHNTHGDNCDQCAKGFYGNA---LGGTPNDCKRCPCPNDGACLQINEDTVICTECPKGYFGSRCEQCSDGFFGDPTGLLGEVQ--TCKSCDCNGN-----VDPNA-VGNCNRTTGECLKCIHNTAGEHCDQCLSGHFGD---PLALPHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGECQPGYFNIRS 949 HSP 3 Score: 62.7734 bits (151), Expect = 1.494e-9 Identity = 46/158 (29.11%), Postives = 72/158 (45.57%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCK---HNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCK 2057
C C G+ + + N +C HNT G CD+C G + L C RC C + + ++ + Q +G +C+ N G C C GY+ + C+ C C VGS N ++CD+ GQC C+ GV+G++CD+C+
Sbjct: 847 CDCNGNVDPNAVGNCNRTTGECLKCIHNTAGEHCDQCLSG----HFGDPLALPHGRCDRCSC--YEAGTEQDEQSITRCDQVTGQC--QCKPNVIGRDCGECQPGYFN-----IRSGNGCENCLCDPVGSYN-STCDRYSGQCHCRPGVMGQRCDQCE 990 HSP 4 Score: 55.0694 bits (131), Expect = 3.351e-7 Identity = 43/159 (27.04%), Postives = 68/159 (42.77%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESS 2126
C CK N G DC +C+ G+ +++ C+ C C+ Y T + G C C+ G +C C+N +Y ++ CK C+C GS CD+ GQC C + V GR+CD+CK C Y++++ +
Sbjct: 926 CQCKPNVIGRDCGECQPGYFNIRSGNG-------CENCLCD--------PVGSYNSTCDRYSGQCH-CRPGVMGQRCDQCENYFYGFSSE------GCKPCECDESGSKGF-QCDQN-GQCPCNDNVEGRRCDRCKENKYDRHRGCIDCPDCYNLVQDA 1060
BLAST of Netrin-1 vs. Ensembl Zebrafish
Match: ntn2 (netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2]) HSP 1 Score: 358.607 bits (919), Expect = 3.572e-112 Identity = 212/646 (32.82%), Postives = 322/646 (49.85%), Query Frame = 3
Query: 699 FNSILLLGFSFYFSVAISVLYENKQTTC-----EFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
F ++L + F S + Q T E G C P FIN A +++V+S CG + C + R C ICD + + LTD + N TCW S + Q +V ++++ K FE+ YV+LQFCS P+S+ IYKS D G+ W P+Q+YS C++ +N P Q E + DL + ++ FS+ GR + L W+T+TD+R+ SR + + + R D L S+ YY V D VGGRC+C GH+++C+ DG ++C+CKHNTEG +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD K ++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K I K + + S + + +S CKP K K + +V + V++ + V G +F + + V++ G + + LW+ +++ C CP I +G+ +LIL + + R L D ++++QWR W RRL+KFQ K + KC K
Sbjct: 4 FQTLLSMLTVFQASSHSPNPFSGPQVTPTDPCYEETGAARRCIPEFINAAFGQEVSVSSVCGRPV-SRSCSLVERDDRPAVRTCQICDASDPRNAHPASYLTDLNSAHNLTCWQSENL--QSSPLNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGRTWTPYQFYSSQCRRMYNRPNKAAITKQNEQEALCTDGHTDL--------YPLSGGLIAFSTLDGRPSGKDFDSSPVLQDWVTVTDIRVVFSRPQ--------HTRALPMSGRESEDALGAP------GSLPTYYYAVGDFQVGGRCKCNGHASRCVREKDGKLLCECKHNTEGPECDRCKPFHYDRPWQRATGKEANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGKAITHRRACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVI------KPTAVISTTEEPADCDSYCKPLKGNLKINMKKYCKKDYAVQVSVLDMETV-GDWAKFSVSLMSVYKSRGDPLKRGDHM--------LWVHMKDLACKCPRIHMGKRFLILGSTEGTANPERPGLQADKNSLVIQWRDIWTRRLRKFQRKEKKGKCSK 608
BLAST of Netrin-1 vs. Ensembl Zebrafish
Match: ntn2 (netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2]) HSP 1 Score: 358.221 bits (918), Expect = 3.955e-112 Identity = 206/613 (33.61%), Postives = 312/613 (50.90%), Query Frame = 3
Query: 783 EFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
E G C P FIN A +++V+S CG + C + R C ICD + + LTD + N TCW S + Q +V ++++ K FE+ YV+LQFCS P+S+ IYKS D G+ W P+Q+YS C++ +N P Q E + DL + ++ FS+ GR + L W+T+TD+R+ SR + + + R D L S+ YY V D VGGRC+C GH+++C+ DG ++C+CKHNTEG +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD K ++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K I K + + S + + +S CKP K K + +V + V++ + V G +F + + V++ G + + LW+ +++ C CP I +G+ +LIL + + R L D ++++QWR W RRL+KFQ K + KC K
Sbjct: 28 EETGAARRCIPEFINAAFGQEVSVSSVCGRPV-SRSCSLVERDDRPAVRTCQICDASDPRNAHPASYLTDLNSAHNLTCWQSENL--QSSPLNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGRTWTPYQFYSSQCRRMYNRPNKAAITKQNEQEALCTDGHTDL--------YPLSGGLIAFSTLDGRPSGKDFDSSPVLQDWVTVTDIRVVFSRPQ--------HTRALPMSGRESEDALGAPG------SLPTYYYAVGDFQVGGRCKCNGHASRCVREKDGKLLCECKHNTEGPECDRCKPFHYDRPWQRATGKEANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGKAITHRRACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVI------KPTAVISTTEEPADCDSYCKPLKGNLKINMKKYCKKDYAVQVSVLDMETV-GDWAKFSVSLMSVYKSRGDPLKRGDHM--------LWVHMKDLACKCPRIHMGKRFLILGSTEGTANPERPGLQADKNSLVIQWRDIWTRRLRKFQRKEKKGKCSK 599
BLAST of Netrin-1 vs. Ensembl Zebrafish
Match: ntn1b (netrin 1b [Source:ZFIN;Acc:ZDB-GENE-990415-168]) HSP 1 Score: 354.369 bits (908), Expect = 1.231e-110 Identity = 216/652 (33.13%), Postives = 332/652 (50.92%), Query Frame = 3
Query: 669 FIRVLMNCFLFNSI--LLLGFSFYFSVAISVLYENKQTTC-EFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKC 2597
IR+L+ C SI ++ G + +++ + C + +G C P F+N A + V+S+CG P C + RDC+ICD + LTD N N TCW S Y Q+ N V ++++ K FEV YV+LQFCS P+S+ I+KS D GK W+P+Q+YS C+K +N P Q E C D + + G ++ FS+ GR + L W+T TD+++T +R H G + + S + + +Y VSDL VGGRC+C GH++KC+ + +GN+VC+CKHNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G++SGGVC C+HNTAG CH+C GYYRD +K +SH ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K +S D + + +S CK K K K + +V + V++ + G+ +F + I V++ G + ++ LW+ ++V C CP I GR YL++ + R + ++ D ++++ W+ W RRL+KFQ + KC
Sbjct: 1 MIRILVTCVSMVSITSMVSGARGGYGMSMFAAQSSPPDPCYDENGNPRRCIPDFVNSAFGKDVRVSSTCGSP-PSRYCVVTEK-GEERSRDCNICDATDPKKTHPPAYLTDLNNPHNLTCWQS-ENYVQYPQN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKTWVPFQFYSTQCKKMYNKPSKAAITKQNEQEA----ICTDSHTDMQPLTGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFNRL-----------------HTFGDENEDDSELARDS-----YFYAVSDLQVGGRCKCNGHASKCVKDREGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKAISHRRACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAAPTSSYSSPDGPT------DCDSHCKAPKGKMKVTMKKYCKKDFAVQVHVLKGDKA-GEWWKFTINIISVYKQGGHRIRRGDQL--------LWVRAKDVACKCPKIKPGRKYLLMGSDEEEDSRGQSGVVADRGSLLIPWKDLWARRLRKFQQRDKRGKC 602
BLAST of Netrin-1 vs. Ensembl Zebrafish
Match: ntn1b (netrin 1b [Source:ZFIN;Acc:ZDB-GENE-990415-168]) HSP 1 Score: 354.369 bits (908), Expect = 1.231e-110 Identity = 216/652 (33.13%), Postives = 332/652 (50.92%), Query Frame = 3
Query: 669 FIRVLMNCFLFNSI--LLLGFSFYFSVAISVLYENKQTTC-EFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKC 2597
IR+L+ C SI ++ G + +++ + C + +G C P F+N A + V+S+CG P C + RDC+ICD + LTD N N TCW S Y Q+ N V ++++ K FEV YV+LQFCS P+S+ I+KS D GK W+P+Q+YS C+K +N P Q E C D + + G ++ FS+ GR + L W+T TD+++T +R H G + + S + + +Y VSDL VGGRC+C GH++KC+ + +GN+VC+CKHNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G++SGGVC C+HNTAG CH+C GYYRD +K +SH ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K +S D + + +S CK K K K + +V + V++ + G+ +F + I V++ G + ++ LW+ ++V C CP I GR YL++ + R + ++ D ++++ W+ W RRL+KFQ + KC
Sbjct: 1 MIRILVTCVSMVSITSMVSGARGGYGMSMFAAQSSPPDPCYDENGNPRRCIPDFVNSAFGKDVRVSSTCGSP-PSRYCVVTEK-GEERSRDCNICDATDPKKTHPPAYLTDLNNPHNLTCWQS-ENYVQYPQN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKTWVPFQFYSTQCKKMYNKPSKAAITKQNEQEA----ICTDSHTDMQPLTGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFNRL-----------------HTFGDENEDDSELARDS-----YFYAVSDLQVGGRCKCNGHASKCVKDREGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKAISHRRACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAAPTSSYSSPDGPT------DCDSHCKAPKGKMKVTMKKYCKKDFAVQVHVLKGDKA-GEWWKFTINIISVYKQGGHRIRRGDQL--------LWVRAKDVACKCPKIKPGRKYLLMGSDEEEDSRGQSGVVADRGSLLIPWKDLWARRLRKFQQRDKRGKC 602
BLAST of Netrin-1 vs. Ensembl Zebrafish
Match: ntn1a (netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169]) HSP 1 Score: 351.673 bits (901), Expect = 1.342e-109 Identity = 217/653 (33.23%), Postives = 337/653 (51.61%), Query Frame = 3
Query: 666 IFIRVLMNCFLFNSILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQ-EQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+ V + C L ++ G S + + + +G C P F+N A ++ +S+CG+ P C + H R+C CD + LTD N N TCW S Y Q+ N V ++++ K FEV YV+LQFCS P+S+ I+KS D GK W+P+QYYS C+K +N P Q E + + D++ + ++ FS+ GR + L W+T TD+++T SR H G + + S + + +Y VSDL VGGRC+C GH+++C+ + DGN+VC+CKHNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C GYYRD +KP+SH ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K ++ ++ S + ES CK K K K + +V + ++++ + G+ +F + I V++ Q S I + +Q+ LW+ ++V C CP I G+ YL+L + + ++ D ++++QWR +W RRL+KFQ + + KC+K
Sbjct: 8 LVTLVTLCCVLKGTVGGYGMSMF-----AAQTSPPDPCYDENGHPRRCIPDFVNAAFGKEVRASSTCGKT-PSRYCVVTEKGDERH-RNCHTCDASDPKKNHPPAYLTDLNNPHNLTCWQSD-NYLQYPQN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKSWVPFQYYSTQCRKMYNKPSKATITKQNEQEAICTDSHTDMHP--------LSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFSRL-----------------HTFGDENEDDSELARDS-----YFYAVSDLQVGGRCKCNGHASRCVKDRDGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKPISHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCANGYQQSRSPIAPCIKIPIAPPTTTASSTEEPS------DCESYCKASKGKLKINMKKYCKKDYAVQVHILKADKA-GEWWKFTVNIISVYK------QGESRIRRGDQF---LWVRAKDVACKCPKIKSGKKYLLLGNDE--DSPGQSGMVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 602
BLAST of Netrin-1 vs. Ensembl Xenopus
Match: rps16 (ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-5786511]) HSP 1 Score: 332.798 bits (852), Expect = 2.066e-102 Identity = 198/620 (31.94%), Postives = 301/620 (48.55%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAE------SILPFSSTIGRKM------NDTLIKWITITDLRITLSR---FDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
HG C P F+N A ++ +S+CG + ++ H CD Y LTD N TCW S + +H +V+++++ K FEV YV+LQFCS P+S+ I+KS D GK W+P+QYYS C+K + P Q N+++ GQ E ++ FS+ GR + L W+T TD+R+ SR ++ S D G F YY V + VGGRC+C GH+++C + + ++CDCKHNTEG +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD ++ ++ ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K ++ + ++ + + E CKP K K + V + V+E E+ G +F + I V++ + LWI +++ C CP I L R YL++ + R L D ++++QWR +W RRL+K Q + + KC K
Sbjct: 45 HGLPRRCVPEFVNAAFNKEVQASSTCGRL------------ATRH------CDTTDPRKSYPASYLTDLNTAGNMTCWRS-ETFPRHSSQNVSLTLSLGKKFEVTYVSLQFCSPRPESVAIFKSMDYGKSWVPYQYYSSQCRKVYGKPSRASVTKQ--------------NEQEALCTDGQTELYPLTGGLIAFSTLDGRPSAQDLDNSPVLQDWLTATDIRVFFSRPHLLGNKESEASDEGPGF--------------------------YYSVGEFQVGGRCKCNGHASRCGKDKEARLICDCKHNTEGPECDRCKPFHYDRPWQRATAREANECMACTCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDVSRAITDRRACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGLTCNRCAKGYQQSRSPIAPCIKIPAVVPTPALTSTE------EPADCEQYCKPPKGNYKINLKKYCKKDFVVQVNVLE-MEMVGSWAKFTVNILSVYKCRDDRIKRGDNF--------LWIHIKDLSCKCPKILLSRRYLVMGSSE--GPSERPGLTADKNSMVIQWRDAWTRRLRKLQRREKKGKCLK 587
BLAST of Netrin-1 vs. Ensembl Xenopus
Match: ntn1 (netrin 1 [Source:NCBI gene;Acc:779839]) HSP 1 Score: 332.028 bits (850), Expect = 4.721e-102 Identity = 197/607 (32.45%), Postives = 316/607 (52.06%), Query Frame = 3
Query: 804 YCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCW--FSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGR------KMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCE 2600
YC P FIN+A ++ +++CG P +C ++ ++ R C +CD R + Y +TD Q TCW SG + Q+ V +++ + FE+ Y +L+FCS PDS+ IYKS D GK WIP+Q+YS +C++ ++ T I + +++ TC D K G ++ F GR + + L W+T TD+R+ +R +GK ++ + +YGVS++ VGGRC+C GH+++C +G ++C+C+HNT G +CD CK ++D W+RA+ N C C+CNLHS C+F +Y +G+KSGGVC C+HNTAG CH+C GY RD +KP++ ACK C+CH +G+ N C++ GQC CK GV G C++C GY Q+RS PCV+ + + ++ + + + + +S CKP R + +K+C++D V + S E G+ +F + V+R + + PLW+ ++ CDC + +G+SYLI+ + R L+LD ++ L WR W +L++FQ + KC
Sbjct: 51 YCIPDFINVALGQEVITSNTCGRT-PQKLC-YFLDSTNVTSRRCQLCDQKRPENSYPPSYMTDTDAQ---TCWKSESGITFPQN----VTLTLPLGRRFELVYASLRFCSPRPDSMAIYKSMDYGKTWIPFQFYSTHCRRVYDQATTSA--ISKPMQHEA--TCTDFQTGVKPLTKG----LVAFMPLAGRPSARRFEYSPVLQDWVTATDIRVVFNRLH--------HGKKMGIRRK-------------------TAFYGVSEIQVGGRCKCNGHASRCTAGKEG-LMCECQHNTIGPECDACKPFYYDRPWQRATPSNAHECVACECNLHSHRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKQGYKRDLSKPITSRKACKPCQCHPIGAVNA-MCNQTTGQCQCKTGVTGPTCNRCAPGYQQSRSAHMPCVRIQEEMTTTASYPQEWKAG-TNGTECQSYCKP-SHSRVHMNLRKYCKKDYVLRAQLLSMEKSGEWWQFTATVLTVYRQ--------RRVPIRRGDQPLWVPDHDLACDCLRVQVGKSYLIIGNDEESPDPAR--LILDKNSLALPWRDVWGHKLRRFQQQERRGKCR 599
BLAST of Netrin-1 vs. Ensembl Xenopus
Match: rps16 (ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-5786511]) HSP 1 Score: 325.865 bits (834), Expect = 4.026e-100 Identity = 195/620 (31.45%), Postives = 294/620 (47.42%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAE------SILPFSSTIGRKM------NDTLIKWITITDLRITLSR---FDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
HG C P F+N A ++ +S+CG + ++ H CD Y LTD N TCW S + +H +V+++++ K FEV YV+LQFCS P+S+ I+KS D GK W+P+QYYS C+K + P Q N+++ GQ E ++ FS+ GR + L W+T TD+R+ SR ++ S D G F YY V + VGGRC+C GH+++C + + ++CDCKHNTEG +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD ++ ++ ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K ++ + P S +P V + V+E E+ G +F + I V++ + LWI +++ C CP I L R YL++ + R L D ++++QWR +W RRL+K Q + + KC K
Sbjct: 45 HGLPRRCVPEFVNAAFNKEVQASSTCGRL------------ATRH------CDTTDPRKSYPASYLTDLNTAGNMTCWRS-ETFPRHSSQNVSLTLSLGKKFEVTYVSLQFCSPRPESVAIFKSMDYGKSWVPYQYYSSQCRKVYGKPSRASVTKQ--------------NEQEALCTDGQTELYPLTGGLIAFSTLDGRPSAQDLDNSPVLQDWLTATDIRVFFSRPHLLGNKESEASDEGPGF--------------------------YYSVGEFQVGGRCKCNGHASRCGKDKEARLICDCKHNTEGPECDRCKPFHYDRPWQRATAREANECMACTCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDVSRAITDRRACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGLTCNRCAKGYQQSRSPIAPCIKIPAVVPT---------------PALTSTEEPA----------------VVQVNVLE-MEMVGSWAKFTVNILSVYKCRDDRIKRGDNF--------LWIHIKDLSCKCPKILLSRRYLVMGSSE--GPSERPGLTADKNSMVIQWRDAWTRRLRKLQRREKKGKCLK 562
BLAST of Netrin-1 vs. Ensembl Xenopus
Match: utp4 (UTP4 small subunit processome component [Source:Xenbase;Acc:XB-GENE-977755]) HSP 1 Score: 221.861 bits (564), Expect = 7.682e-59 Identity = 153/477 (32.08%), Postives = 230/477 (48.22%), Query Frame = 3
Query: 705 SILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNH---VNISIAFKKNFEVFYVALQFCSELPDSITIYK-SHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYR-DWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQ-TRSMLKPCV 2099
++LLLG A+ YE G C P F+N A A + T++CG P++ C + + C ICD+ + + + + LTD NQ T W S + G+ + +N+++ K F++ YV L+F + P+S +YK +H++G WIP+QYYS +C+K + E + +L F GN+ FS+ GR + L +W+T TD+R+TL+R + F + K + YY +SD +VGGRC+C GH+++C+ N IVC+CKHNT G+DC+KC ++D W R++ +P C C CN SQ C F+ +Y TG GG C C NT G C C YYR D +P C C+C+ VGS + CD G+C CK GV+G KCD+C+ G+ T + +PC
Sbjct: 5 AVLLLG---TVRAAMDECYE--------EGSPQRCMPEFVNAAFNATVVATNTCG-TPPEEYCVQTGV--TGVTKSCHICDSGQFHLQHGAEYLTDYNNQAEITWWQSQTML--AGIQYPSTINLTLHLGKAFDITYVRLKFHTSRPESFALYKRTHEDGP-WIPYQYYSGSCEKTYQKFNRGFIRTGEDEQQALCTDEFSDISPLTGGNVA-------FSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFS-----------------------DPKVLKSYYYAISDFAVGGRCKCNGHASECVRNEFEKIVCNCKHNTFGSDCEKCLPFYNDRPWRRSTADSPNECLPCNCNGRSQECYFDPELYRSTGH--GGHCTGCADNTDGPNCERCRENYYRQDNNEP------CHACQCNPVGSLSTQ-CD-NYGRCSCKPGVMGEKCDRCQPGFHSLTEAGCRPCA 424 HSP 2 Score: 75.485 bits (184), Expect = 4.330e-13 Identity = 50/163 (30.67%), Postives = 78/163 (47.85%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLA---CKKCKC-HAVGSTNVNSCDKKLGQCF-CKEGVIGRKCDKCKIGY 2066
C C GHS+ C + + VCDC+HNT G C++C EG+ + ++ + C+ C C S + + VC C T G +C CD+GY+ D PL + A C+ C+C + + V +CD+ G+C C G CD+C+ G+
Sbjct: 702 CTCNGHSDTC---DPESGVCDCQHNTAGPHCERCSEGY----YGDSTTGSASDCQPCPCPGGSSCAVVPRTKEV--------VCTNCPLGTTGKRCELCDDGYFGD---PLGENGAPRPCRICECSNNIDPNAVGNCDRLTGECLKCIYNTGGFYCDRCRDGF 846 HSP 3 Score: 70.0922 bits (170), Expect = 1.677e-11 Identity = 56/181 (30.94%), Postives = 84/181 (46.41%), Query Frame = 3
Query: 1548 SKVYYGVSDLSVGGRCQ---CYGHSNKCIINNDGNIVC-DCKHNTEGADCDKCKEG-FHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSH--DLACKKCKCHAVGSTNVNS-CDKKLGQCFCKEGVIGRKCDKCKIGY 2066
S+ YYG S CQ C G S+ ++ +VC +C T G C+ C +G F D E + P C+ C+C+ + + N + +G C KC +NT G C C +G+Y + PL+ DL C+ C C+ G+ S C++ GQC C V R C C+ G+
Sbjct: 733 SEGYYGDSTTGSASDCQPCPCPGGSSCAVVPRTKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGA---PRPCRICECSNN-----IDPNAVGNCDRLTG-ECLKCIYNTGGFYCDRCRDGFYGN---PLAQNPDLKCRACSCNPYGTVKGQSGCNQVTGQCECLPHVTERDCSACEPGF 901 HSP 4 Score: 66.6254 bits (161), Expect = 1.895e-10 Identity = 52/155 (33.55%), Postives = 67/155 (43.23%), Query Frame = 3
Query: 1647 VCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGY----LQTRSMLKPC 2096
+C C G C++C G+ + E S+ P+S C C CN HS C E GVC CQHNTAG C C GYY D T + D C+ C C S V K++ C G G++C+ C GY L +PC
Sbjct: 667 ICSCPTGYIGQFCERCAPGY---RRENPSQ-GPYSPCVLCTCNGHSDTCDPES-----------GVC-DCQHNTAGPHCERCSEGYYGDSTTGSASD--CQPCPCPGGSSCAVVPRTKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRPC 803 HSP 5 Score: 55.4546 bits (132), Expect = 5.411e-7 Identity = 43/145 (29.66%), Postives = 69/145 (47.59%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQC-NLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRS 2081
C+C + DC C+ GF++L L+ C+RC C +L S + + ++TGQ C +C +G QC C+ ++ + CK C C GS ++ K+ G+C CK G +G +CD+C+ Y RS
Sbjct: 883 CECLPHVTERDCSACEPGFYNL-------LSGRGCERCDCHSLGSTSGQCD----VRTGQ-----C-ECHPGISGQQCQQCEPNHFGFGPE------GCKPCDCDPEGSGSLQC--KEDGRCECKSGFVGTRCDQCEENYFYNRS 1002
BLAST of Netrin-1 vs. Ensembl Xenopus
Match: utp4 (UTP4 small subunit processome component [Source:Xenbase;Acc:XB-GENE-977755]) HSP 1 Score: 221.476 bits (563), Expect = 8.338e-59 Identity = 153/477 (32.08%), Postives = 230/477 (48.22%), Query Frame = 3
Query: 705 SILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNH---VNISIAFKKNFEVFYVALQFCSELPDSITIYK-SHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYR-DWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQ-TRSMLKPCV 2099
++LLLG A+ YE G C P F+N A A + T++CG P++ C + + C ICD+ + + + + LTD NQ T W S + G+ + +N+++ K F++ YV L+F + P+S +YK +H++G WIP+QYYS +C+K + E + +L F GN+ FS+ GR + L +W+T TD+R+TL+R + F + K + YY +SD +VGGRC+C GH+++C+ N IVC+CKHNT G+DC+KC ++D W R++ +P C C CN SQ C F+ +Y TG GG C C NT G C C YYR D +P C C+C+ VGS + CD G+C CK GV+G KCD+C+ G+ T + +PC
Sbjct: 8 AVLLLG---TVRAAMDECYE--------EGSPQRCMPEFVNAAFNATVVATNTCG-TPPEEYCVQTGV--TGVTKSCHICDSGQFHLQHGAEYLTDYNNQAEITWWQSQTML--AGIQYPSTINLTLHLGKAFDITYVRLKFHTSRPESFALYKRTHEDGP-WIPYQYYSGSCEKTYQKFNRGFIRTGEDEQQALCTDEFSDISPLTGGNVA-------FSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFS-----------------------DPKVLKSYYYAISDFAVGGRCKCNGHASECVRNEFEKIVCNCKHNTFGSDCEKCLPFYNDRPWRRSTADSPNECLPCNCNGRSQECYFDPELYRSTGH--GGHCTGCADNTDGPNCERCRENYYRQDNNEP------CHACQCNPVGSLSTQ-CD-NYGRCSCKPGVMGEKCDRCQPGFHSLTEAGCRPCA 427 HSP 2 Score: 75.0998 bits (183), Expect = 5.133e-13 Identity = 50/163 (30.67%), Postives = 78/163 (47.85%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLA---CKKCKC-HAVGSTNVNSCDKKLGQCF-CKEGVIGRKCDKCKIGY 2066
C C GHS+ C + + VCDC+HNT G C++C EG+ + ++ + C+ C C S + + VC C T G +C CD+GY+ D PL + A C+ C+C + + V +CD+ G+C C G CD+C+ G+
Sbjct: 705 CTCNGHSDTC---DPESGVCDCQHNTAGPHCERCSEGY----YGDSTTGSASDCQPCPCPGGSSCAVVPRTKEV--------VCTNCPLGTTGKRCELCDDGYFGD---PLGENGAPRPCRICECSNNIDPNAVGNCDRLTGECLKCIYNTGGFYCDRCRDGF 849 HSP 3 Score: 69.707 bits (169), Expect = 2.315e-11 Identity = 56/181 (30.94%), Postives = 84/181 (46.41%), Query Frame = 3
Query: 1548 SKVYYGVSDLSVGGRCQ---CYGHSNKCIINNDGNIVC-DCKHNTEGADCDKCKEG-FHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSH--DLACKKCKCHAVGSTNVNS-CDKKLGQCFCKEGVIGRKCDKCKIGY 2066
S+ YYG S CQ C G S+ ++ +VC +C T G C+ C +G F D E + P C+ C+C+ + + N + +G C KC +NT G C C +G+Y + PL+ DL C+ C C+ G+ S C++ GQC C V R C C+ G+
Sbjct: 736 SEGYYGDSTTGSASDCQPCPCPGGSSCAVVPRTKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGA---PRPCRICECSNN-----IDPNAVGNCDRLTG-ECLKCIYNTGGFYCDRCRDGFYGN---PLAQNPDLKCRACSCNPYGTVKGQSGCNQVTGQCECLPHVTERDCSACEPGF 904 HSP 4 Score: 66.6254 bits (161), Expect = 2.208e-10 Identity = 52/155 (33.55%), Postives = 67/155 (43.23%), Query Frame = 3
Query: 1647 VCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGY----LQTRSMLKPC 2096
+C C G C++C G+ + E S+ P+S C C CN HS C E GVC CQHNTAG C C GYY D T + D C+ C C S V K++ C G G++C+ C GY L +PC
Sbjct: 670 ICSCPTGYIGQFCERCAPGY---RRENPSQ-GPYSPCVLCTCNGHSDTCDPES-----------GVC-DCQHNTAGPHCERCSEGYYGDSTTGSASD--CQPCPCPGGSSCAVVPRTKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRPC 806 HSP 5 Score: 55.0694 bits (131), Expect = 6.919e-7 Identity = 43/145 (29.66%), Postives = 69/145 (47.59%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQC-NLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRS 2081
C+C + DC C+ GF++L L+ C+RC C +L S + + ++TGQ C +C +G QC C+ ++ + CK C C GS ++ K+ G+C CK G +G +CD+C+ Y RS
Sbjct: 886 CECLPHVTERDCSACEPGFYNL-------LSGRGCERCDCHSLGSTSGQCD----VRTGQ-----C-ECHPGISGQQCQQCEPNHFGFGPE------GCKPCDCDPEGSGSLQC--KEDGRCECKSGFVGTRCDQCEENYFYNRS 1005
BLAST of Netrin-1 vs. Ensembl Mouse
Match: Ntn1 (netrin 1 [Source:MGI Symbol;Acc:MGI:105088]) HSP 1 Score: 339.347 bits (869), Expect = 6.527e-105 Identity = 208/616 (33.77%), Postives = 316/616 (51.30%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKY-----YSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+G C P F+N A + V+S+CG P +Y R C +C++ + LTD N N TCW S Y Q N V ++++ K FEV YV+LQFCS P+S+ IYKS D G+ W+P+Q+YS C+K +N P PI + E C D + + + G ++ FS+ GR + L W+T TD+R+ SR H G + + S + + YY VSDL VGGRC+C GH+ +C+ + D ++VCDC+HNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD KP++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + T S + + + +S CK K K K + +V + ++++ + G +F + I V++ Q S I + + LWI ++ C CP I + YL+L + + ++ D ++++QWR +W RRL+KFQ + + KC+K
Sbjct: 45 NGHPRRCIPDFVNAAFGKDVRVSSTCGR-------PPARYCVVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQS-ENYLQFPHN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP--HRAPITKQNEQEA--VCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRL-----------------HTFGDENEDDSELARDS-----YYYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKI--PVAPPTTAASSVE----EPEDCDSYCKASKGKLKMNMKKYCRKDYAVQIHILKADKA-GDWWKFTVNIISVYK------QGTSRIRRGDQS--LWIRSRDIACKCPKIKPLKKYLLLGNAE--DSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. Ensembl Mouse
Match: Ntn1 (netrin 1 [Source:MGI Symbol;Acc:MGI:105088]) HSP 1 Score: 339.347 bits (869), Expect = 6.527e-105 Identity = 208/616 (33.77%), Postives = 316/616 (51.30%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKY-----YSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+G C P F+N A + V+S+CG P +Y R C +C++ + LTD N N TCW S Y Q N V ++++ K FEV YV+LQFCS P+S+ IYKS D G+ W+P+Q+YS C+K +N P PI + E C D + + + G ++ FS+ GR + L W+T TD+R+ SR H G + + S + + YY VSDL VGGRC+C GH+ +C+ + D ++VCDC+HNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD KP++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + T S + + + +S CK K K K + +V + ++++ + G +F + I V++ Q S I + + LWI ++ C CP I + YL+L + + ++ D ++++QWR +W RRL+KFQ + + KC+K
Sbjct: 45 NGHPRRCIPDFVNAAFGKDVRVSSTCGR-------PPARYCVVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQS-ENYLQFPHN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP--HRAPITKQNEQEA--VCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRL-----------------HTFGDENEDDSELARDS-----YYYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKI--PVAPPTTAASSVE----EPEDCDSYCKASKGKLKMNMKKYCRKDYAVQIHILKADKA-GDWWKFTVNIISVYK------QGTSRIRRGDQS--LWIRSRDIACKCPKIKPLKKYLLLGNAE--DSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. Ensembl Mouse
Match: Ntn3 (netrin 3 [Source:MGI Symbol;Acc:MGI:1341188]) HSP 1 Score: 302.753 bits (774), Expect = 2.077e-91 Identity = 187/635 (29.45%), Postives = 292/635 (45.98%), Query Frame = 3
Query: 684 MNCFLFNSILLLGFSFYFSVAISVLYENKQTTCEFHGKD-YYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFN-LPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVY-YGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLIL----MKYKIYHHRHREELLLDSRTVMLQWRPSW 2549
M +L+ +L G S A+S C ++ C P +N A ++ +S+CG S+N +CD+ +S LT + CW S + Q N V +++ K FE+ +V+L+FCS P S+ + KS D+G+ W+P ++S +C + LP + P G E CF Q Q DG +L FS G + L W+T TD+RI L+R Q + D ++ Y Y ++L VGGRC+C GH+++C+++ G++VCDC+H TEG DC +CK + D W+RA+ +C C CN H++ C+F +Y +G++SGGVC C+HNTAG CH+C G+YRD + LS AC+ C CH VG+ +C++ GQC CK+GV G C++C G+ Q+RS + PCVKT + + S + + + ES C+P + K + +V + V E G RF + + V+R E + + LW+ + C CP + GR YL+L + L +++L WR +W
Sbjct: 1 MPTWLWGLLLTAG---TLSAALSPGLPASADPCYDEAREPRSCIPGLVNAALGREVLASSTCGR-------------SANR-----VCDSSDPQRAHSADLLTSAPGTASPLCWRSD-LLQQAPFN-VTLTVPLGKAFELVFVSLRFCSAPPTSVALLKSQDHGRSWVPLGFFSSSCTLDYGRLPAPADGPSGPGPEA----LCFPAPQAQPDGG-----GLLAFSVQDGSPQGLDLDNSPVLQDWVTATDIRIVLTRPAIQGDT--------------------------RDGGVTVPYSYSATELQVGGRCKCNGHASRCLLDTHGHLVCDCQHGTEGPDCSRCKPFYCDRPWQRATGQEAHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRVLSDRRACRACDCHPVGAAG-KTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKT--PVPGPTEESSPVEPQ-----DCESHCRPARGSYRISLKKFCRKDYAVQVAVGARGEARGSWTRFPVAVLAVFRS--------GEERARRGSSALWVPTLDAACGCPRLLPGRRYLLLGGGPGAAAGSTAGRGQGLSAARGSLVLPWRDAW 561
BLAST of Netrin-1 vs. Ensembl Mouse
Match: Lamc1 (laminin, gamma 1 [Source:MGI Symbol;Acc:MGI:99914]) HSP 1 Score: 216.468 bits (550), Expect = 2.734e-57 Identity = 139/443 (31.38%), Postives = 213/443 (48.08%), Query Frame = 3
Query: 792 GKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVY-NQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQ-TRSMLKPC 2096
G+ C P F+N A + T++CG P++ C + + C +CD +++ + LTD NQ + T W S + N +N+++ K F++ YV L+F + P+S IYK WIP+QYYS +C+ ++ + +L F GN+ FS+ GR + L +W+T TD+R+TL+R + G ++ N + K + YY +SD +VGGRC+C GH+++C+ N ++C+CKHNT G DC+KC F+D W RA+ + C C CN SQ C F+ +Y TG GG C C+ NT G +C C ++R L + AC C C VGS + CD G+C CK GV+G KCD+C+ G+ T + +PC
Sbjct: 43 GRPQRCMPEFVNAAFNVTVVATNTCG-TPPEEYCVQTGV--TGVTKSCHLCDAGQQHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVA-------FSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRL-----------------NTFGDEVFN------DPKVLKSYYYAISDFAVGGRCKCNGHASECVKNEFDKLMCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGH--GGHCTNCRDNTDGAKCERCRENFFR-----LGNTEACSPCHCSPVGSLSTQ-CD-SYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPC 443 HSP 2 Score: 71.633 bits (174), Expect = 4.162e-12 Identity = 59/184 (32.07%), Postives = 80/184 (43.48%), Query Frame = 3
Query: 1548 SKVYYGVSDLSVGGRCQ---CYGHSNKCIINNDGNIVCD-CKHNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGST-NVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRS 2081
S YYG S L CQ C G S+ I+ +VC C T G C+ C +G+ + P C+ CQCN + + N + +G C KC +NTAG C C G++ + P D CK C C+ G+ +SC+ GQC C V GR C C GY +S
Sbjct: 753 SDGYYGDSTLGTSSDCQPCPCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGYF---GDPLGSNGPVRLCRPCQCNDN-----IDPNAVGNCNRLTG-ECLKCIYNTAGFYCDRCKEGFFGNPLAPNPAD-KCKACACNPYGTVQQQSSCNPVTGQCQCLPHVSGRDCGTCDPGYYNLQS 926 HSP 3 Score: 71.633 bits (174), Expect = 4.569e-12 Identity = 53/173 (30.64%), Postives = 74/173 (42.77%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHA-VGSTNVNSCDKKLGQCF-CKEGVIGRKCDKCKIGYLQTRSMLKPCVK 2102
C C GHS C + VCDC+ NT G C+KC +G++ S L S C+ C C S K + VC C TAG +C CD+GY+ D C+ C+C+ + V +C++ G+C C G CD+CK G+ P K
Sbjct: 722 CTCNGHSETC---DPETGVCDCRDNTAGPHCEKCSDGYYG-----DSTLGTSSDCQPCPCPGGSSCAIVPKTKEV--------VCTHCPTGTAGKRCELCDDGYFGDPLGSNGPVRLCRPCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKEGFFGNPLAPNPADK 878 HSP 4 Score: 62.3882 bits (150), Expect = 2.944e-9 Identity = 46/141 (32.62%), Postives = 59/141 (41.84%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYL 2069
C C G C+ C G+ L P+S C C CN HS+ C E GVC C+ NTAG C C +GYY D T S D C+ C C S + K++ C G G++C+ C GY
Sbjct: 688 CTCPVGYGGQFCETCLPGYR----RETPSLGPYSPCVLCTCNGHSETCDPET-----------GVC-DCRDNTAGPHCEKCSDGYYGDSTLGTSSD--CQPCPCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGYF 810 HSP 5 Score: 62.003 bits (149), Expect = 4.311e-9 Identity = 59/214 (27.57%), Postives = 83/214 (38.79%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCK---HNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFC-----------------------------------------------KEGVIGRKCDKCKIGYLQTRS 2081
CQC + + + N + +C +NT G CD+CKEGF + NP CK C CN + + + + TGQ C +C + +G C CD GYY L C++C CHA+GSTN CD + GQC C +EG +G +CD+C+ Y RS
Sbjct: 826 CQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKEGF----FGNPLAPNPADKCKACACNPYGT-VQQQSSCNPVTGQ-----C-QCLPHVSGRDCGTCDPGYYN-----LQSGQGCERCDCHALGSTN-GQCDIRTGQCECQPGITGQHCERCETNHFGFGPEGCKPCDCHHEGSLSLQCKEDGRCECREGFVGNRCDQCEENYFYNRS 1022
BLAST of Netrin-1 vs. Ensembl Mouse
Match: Lamc3 (laminin gamma 3 [Source:MGI Symbol;Acc:MGI:1344394]) HSP 1 Score: 214.542 bits (545), Expect = 1.096e-56 Identity = 135/433 (31.18%), Postives = 203/433 (46.88%), Query Frame = 3
Query: 792 GKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGP--VYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGR------KMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGY 2066
G+ C P F N A + + +CG P+D CPH + C CD+ + LTD + + + W+ P + VN++++ K +E+ YV L+F + P+S IYK W P+QYYS +CQK + P E + + F GN+ FS+ GR + + L +W+T TD+ I+L D+++++ D DI + + + YY VSD SVGGRC+C GH+++C N G + C C+HNT G DC++C F D W R + + C C C+ HS+ C F++ +Y TG GG C++C+ +T G C C+ YYR W S C+ C CH GS ++ CD G C CK V G KCD+C G+
Sbjct: 39 GRAQRCLPEFENAAFGRRAEASHTCGRP-PEDFCPHVGAPGAG--LQCQRCDDADPGRRHDASYLTD-FHSPDDSTWWQSPSMAFGVQYPTSVNLTLSLGKAYEITYVRLKFHTSRPESFAIYKRTYASGPWEPYQYYSASCQKTYGRPEGHYLRPGEDERVAFCTSEFSDISPLNGGNVA-------FSTLEGRPSAYNFEESPVLQEWVTSTDILISL----DRLNTFGD-------------DIFK------DPRVLQSYYYAVSDFSVGGRCKCNGHASECEPNAAGQLACRCQHNTTGVDCERCLPFFQDRPWARGTAEDANECLPCNCSGHSEECTFDRELYRSTGH--GGHCQRCRDHTTGPHCERCEKNYYR-W----SPKTPCQPCDCHPAGSLSLQ-CDNS-GVCPCKPTVTGWKCDRCLPGF 428 HSP 2 Score: 81.6481 bits (200), Expect = 4.110e-15 Identity = 59/169 (34.91%), Postives = 78/169 (46.15%), Query Frame = 3
Query: 1590 RCQCYGHSNKCIINNDGNIVCD--------CKHNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYL 2069
RCQC G+ + +N GN CD C +NT GA C+ C+EGF+ A P C C C+L +V KT G C C +G C C G+Y L C+ CKCH +GS N C K GQC C+ GV G+ CD+C++G+
Sbjct: 821 RCQCSGNVD---LNAVGN--CDPHSGHCLRCLYNTTGAHCEHCREGFYG----SAVATRPVDKCAPCSCDLRG-------SVSEKTCNPVTGQC-VCLPYVSGRDCSRCSPGFYD-----LQSGRGCQSCKCHPLGSLE-NKCHPKTGQCPCRPGVTGQACDRCQLGFF 966 HSP 3 Score: 75.8702 bits (185), Expect = 2.147e-13 Identity = 51/166 (30.72%), Postives = 72/166 (43.37%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCD-CKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDW--TKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRS 2081
C C G S I G++VC C G C+ C++GF + P C+RCQC+ + + N SG C +C +NT G C C G+Y T+P+ C C C GS + +C+ GQC C V GR C +C G+ +S
Sbjct: 767 CPCPGQSACATIPESGDVVCTHCPPGQRGRRCESCEDGFFGDPLGLSGAPQP--CRRCQCSGN-----VDLNAVGNCDPHSG-HCLRCLYNTTGAHCEHCREGFYGSAVATRPVDK---CAPCSCDLRGSVSEKTCNPVTGQCVCLPYVSGRDCSRCSPGFYDLQS 921 HSP 4 Score: 60.8474 bits (146), Expect = 8.254e-9 Identity = 46/172 (26.74%), Postives = 68/172 (39.53%), Query Frame = 3
Query: 1602 YGHSNKCIINNDGNI-----VCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGG-VCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHA-VGSTNVNSCDKKLGQCF-CKEGVIGRKCDKCKIGYLQTRSMLKP 2093
Y + C N G +C C H+TEG C++C GF+ N FS + C Q C T +SG VC C G +C C++G++ D C++C+C V V +CD G C C G C+ C+ G+ + +P
Sbjct: 713 YANCIPCTCNQHGTCDPNTGICLCGHHTEGPSCERCMPGFYG---------NAFSGRADDC----QPCPCPGQSACATIPESGDVVCTHCPPGQRGRRCESCEDGFFGDPLGLSGAPQPCRRCQCSGNVDLNAVGNCDPHSGHCLRCLYNTTGAHCEHCREGFYGSAVATRP 871 HSP 5 Score: 56.9954 bits (136), Expect = 1.318e-7 Identity = 45/175 (25.71%), Postives = 73/175 (41.71%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYL--QTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDM 2168
C C G DC +C GF+DLQ R C+ C+C+ E + KTGQ C+ G C C G++ K C+ C+C +G+ + + C + C C+ G +G KCD+C+ + + + C Y +++ K L ++ M M
Sbjct: 898 CVCLPYVSGRDCSRCSPGFYDLQSGRG-------CQSCKCHPLG---SLENKCHPKTGQC------PCRPGVTGQACDRCQLGFFGFSIK------GCRDCRCSPLGAAS-SQCHEN-STCVCRPGFVGYKCDRCQDNFFLADGDTGCQECPTCYALVKEEAAK---LKARLMLM 1045
BLAST of Netrin-1 vs. UniProt/SwissProt
Match: sp|Q90922|NET1_CHICK (Netrin-1 OS=Gallus gallus OX=9031 GN=NTN1 PE=1 SV=1) HSP 1 Score: 339.732 bits (870), Expect = 3.489e-104 Identity = 206/611 (33.72%), Postives = 318/611 (52.05%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
HG C P F+N A ++ V+S+CG+ P C + R C +C+ + LTD N N TCW S Y Q+ N V ++++ K FEV YV+LQFCS P+S+ IYKS D GK W+P+Q+YS C+K +N P Q E C D + + + G ++ FS+ GR + L W+T TD+++T SR H G + + S + + +Y VSDL VGGRC+C GH+++C+ + D N+VCDCKHNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD +KP+SH ACK+C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + ++ + + +S CK K K K + +V + ++++ E + +F + I V++ + S + Q LW+ +++ C CP + + YL+L + + ++ D ++++QWR +W RRL+KFQ + + KC K
Sbjct: 47 HGLPRRCIPDFVNSAFGKEVKVSSTCGKP-PSRYCVVTEK-GEEQVRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSD-SYVQYPHN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNKPSRAAITKQNEQEA----ICTDSHTDVRPLSGG----LIAFSTLDGRPTAHDFDNSPVLQDWVTATDIKVTFSRL-----------------HTFGDENEDDSELARDS-----YFYAVSDLQVGGRCKCNGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKECDCHPVGAAG-QTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPAAPPPTAASSTE------EPADCDSYCKASKGKLKINMKKYCKKDYAVQIHILKA-EKNADWWKFTVNIISVYK---QGSNRLRRGDQT-----LWVHAKDIACKCPKVKPMKKYLLLGSTE--DSPDQSGIIADKSSLVIQWRDTWARRLRKFQQREKKGKCRK 605
BLAST of Netrin-1 vs. UniProt/SwissProt
Match: sp|O09118|NET1_MOUSE (Netrin-1 OS=Mus musculus OX=10090 GN=Ntn1 PE=1 SV=3) HSP 1 Score: 339.347 bits (869), Expect = 4.565e-104 Identity = 208/616 (33.77%), Postives = 316/616 (51.30%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKY-----YSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+G C P F+N A + V+S+CG P +Y R C +C++ + LTD N N TCW S Y Q N V ++++ K FEV YV+LQFCS P+S+ IYKS D G+ W+P+Q+YS C+K +N P PI + E C D + + + G ++ FS+ GR + L W+T TD+R+ SR H G + + S + + YY VSDL VGGRC+C GH+ +C+ + D ++VCDC+HNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD KP++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + T S + + + +S CK K K K + +V + ++++ + G +F + I V++ Q S I + + LWI ++ C CP I + YL+L + + ++ D ++++QWR +W RRL+KFQ + + KC+K
Sbjct: 45 NGHPRRCIPDFVNAAFGKDVRVSSTCGR-------PPARYCVVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQS-ENYLQFPHN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP--HRAPITKQNEQEA--VCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRL-----------------HTFGDENEDDSELARDS-----YYYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKI--PVAPPTTAASSVE----EPEDCDSYCKASKGKLKMNMKKYCRKDYAVQIHILKADKA-GDWWKFTVNIISVYK------QGTSRIRRGDQS--LWIRSRDIACKCPKIKPLKKYLLLGNAE--DSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. UniProt/SwissProt
Match: sp|O95631|NET1_HUMAN (Netrin-1 OS=Homo sapiens OX=9606 GN=NTN1 PE=1 SV=2) HSP 1 Score: 338.191 bits (866), Expect = 1.219e-103 Identity = 208/616 (33.77%), Postives = 315/616 (51.14%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKY-----YSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+G C P F+N A + V+S+CG P +Y R C +C+ + LTD N N TCW S Y Q N V ++++ K FEV YV+LQFCS P+S+ IYKS D G+ W+P+Q+YS C+K +N P PI + E C D + + + G ++ FS+ GR + L W+T TD+R+ SR H G + + S + + +Y VSDL VGGRC+C GH+ +C+ + D ++VCDC+HNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C GYYRD KP++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + T S + + + +S CK K K K + +V + ++++ + G +F + I V++ Q S I + + LWI ++ C CP I + YL+L + + ++ D ++++QWR +W RRL+KFQ + + KC+K
Sbjct: 45 NGHPRRCIPDFVNAAFGKDVRVSSTCGR-------PPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQS-ENYLQFPHN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP--HRAPITKQNEQEA--VCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRL-----------------HTFGDENEDDSELARDS-----YFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKI--PVAPPTTAASSVE----EPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHILKADKA-GDWWKFTVNIISVYK------QGTSRIRRGDQS--LWIRSRDIACKCPKIKPLKKYLLLGNAE--DSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. UniProt/SwissProt
Match: sp|Q924Z9|NET1_RAT (Netrin-1 OS=Rattus norvegicus OX=10116 GN=Ntn1 PE=1 SV=1) HSP 1 Score: 333.183 bits (853), Expect = 1.166e-101 Identity = 206/616 (33.44%), Postives = 313/616 (50.81%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKY-----YSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+G C P F+N A + V+S+CG P +Y R C +C++ + LTD N N TCW S Y Q N V ++++ K FEV YV+LQFCS P+S+ IYKS D G+ W+P+Q+YS C+K +N P PI + E C D + + + G ++ FS+ GR + L W+T TD+R+ SR H G + + S + + YY VSDL VGGRC+C GH+ +C+ + D ++VCDC+HNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD KP++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + T S + + + +S CK K K K + +V + ++++ + G +F + I V++ Q S I + + LWI ++ CP I + YL+L + + ++ D +++QWR +W RR +KFQ + + KC+K
Sbjct: 45 NGHPRRCIPDFVNAAFGKDVRVSSTCGR-------PPARYCVVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQS-ENYLQFPHN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP--HRAPITKQNEQEA--VCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRL-----------------HTFGDENEDDSELARDS-----YYYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKI--PVAPPTTAASSME----EPEDCDSYCKASKGKLKMNMKKYCRKDYAVQIHILKADKA-GDWWKFTVNIISVYK------QGTSRIRRGDQS--LWIRSRDIAXKCPKIKPLKKYLLLGNAE--DSPDQSGIVADKSXLVIQWRDTWARRXRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. UniProt/SwissProt
Match: sp|Q2HXW4|NET1_PIG (Netrin-1 OS=Sus scrofa OX=9823 GN=NTN1 PE=2 SV=1) HSP 1 Score: 332.798 bits (852), Expect = 1.288e-101 Identity = 205/612 (33.50%), Postives = 311/612 (50.82%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKY-----YSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEE 2591
+G C P F+N A + V+S+CG P +Y R C +C+ + LTD N N TCW S Y Q N V ++++ K FEV YV+LQFCS P+S+ IYKS D G+ W+P+Q+YS C+K +N P PI + E C D + + + G ++ FS+ GR + L W+T TD+R+ SR H G + + S + + +Y VSDL VGGRC+C GH+ +C+ + D ++VCDC+HNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C GY+RD KP++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + T S + + + +S CK K K K + +V + ++++ + G +F + I V++ Q S I + LWI ++ C CP I + YL+L + + ++ D ++++QWR +W RRL+KFQ + +E
Sbjct: 45 NGHPRRCIPDFVNAAFGKDVRVSSTCGR-------PPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQS-ENYLQFPHN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP--HRAPITKQNEQEA--VCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRL-----------------HTFGDENEDDSELARD-----SYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYFRDLGKPITHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGVTCNRCAKGYQQSRSPIAPCIKI--PVAPPTTAASSVE----EPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHILKADKA-GDWWKFTVNIISVYK------QGASRIRRGDQN--LWIRSRDIACKCPKIKPLKKYLLLGNAE--DSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKE 599
BLAST of Netrin-1 vs. TrEMBL
Match: A0A4D6G2V3 (Netrin-4 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=netrin-4 PE=2 SV=1) HSP 1 Score: 543.888 bits (1400), Expect = 0.000e+0 Identity = 276/276 (100.00%), Postives = 276/276 (100.00%), Query Frame = 3
Query: 1707 HDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQ 2534
HDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEKRKRIRFKKFCRRDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQ
Sbjct: 1 HDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEKRKRIRFKKFCRRDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQ 276
BLAST of Netrin-1 vs. TrEMBL
Match: A0A3Q0KPX7 (Putative netrin OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 456.447 bits (1173), Expect = 2.484e-143 Identity = 264/686 (38.48%), Postives = 372/686 (54.23%), Query Frame = 3
Query: 747 ISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEI-LPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM----NDTLIKWITITDLRITLSRFDD-------------------------QMSSYFDYGKYFLLKHRRGRDILNMST--------FSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCI--------INNDGN---------IVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDII-----ESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQ---YAVPLWISHEEV-----RCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCE 2600
I V+YE ++ C G+ C+PPF NIA+ I TS+CG+ ++IC Y H + C C K + LTD N TCW SG V + VN++++ K FEV+Y++LQ C +LPDSI +YKS D G W PWQY+S +C +AF+LP + E Q L C L GN GQ+ +++ FS+TIGR + LI W+T+TDLRI+L RF + ++S G + L+MS +S KS + V++ SDLS+GGRC+C GH+N+CI I D N + CDC+HNTEGADC++C G+ D W R + + CKRC CNLHS C F +Y+ + + SGGVC+ CQHNT G +CH C GYYRDWTKP+SHD C +C+CH +GS CD+K GQC CK GV+G+ C++C+ GY QTR PC+K + E+ QT S + P T +C PC+ +KRIRFKKFCR ++VF G+++S+ +HG ++R E+ I+ WR++G + + + Y V L I + RC CPN+ +G+SYL + + + R ELLLD+ +V+L+WR SW RRL KF +A E C+
Sbjct: 43 IKVIYEATRSVCYTKGQAIECSPPFTNIAESVDIKATSTCGQFDQSEEIC----RYVMGHEK-CETCGKGEK---FGTHLLTDRHQMNNETCWVSGSVLPG---DTVNLTLSLGKRFEVYYISLQPCGQLPDSIALYKSSDFGVTWKPWQYFSTDCYRAFHLPTSNEHNAQISLANIQEVLCVALKSPDVHGNSGQSSNVIAFSTTIGRPSMQPWSSALIDWMTMTDLRISLMRFPEYRDEVQYDSNGLFLNPSFLKPTNVFRVSGSPSIGGFGTNPVLSEAGTLDMSQHLYQSDMHYSKTPKSKTPVHFSFSDLSIGGRCKCNGHANRCIRDRIVGTGITTDNNGQTKSQWGPLRCDCQHNTEGADCERCSPGYLDRPWARGTSESANDCKRCDCNLHSNSCVFSNQLYLMSMKVSGGVCQDCQHNTVGRKCHNCVTGYYRDWTKPVSHDQVCLECRCHPIGSIANQHCDRKTGQCPCKPGVVGQACNRCQEGYKQTRLPDAPCIKAMEHYAHRRKENDQTSHS--TKSQLSKPETNIDCPPCERSKKRIRFKKFCRNEAVFRGIVKSRTIHGDLMRLEVGIQNTWRITGAAEHLLPKTASPNLPAYRVWLRIKNNSADKRHSRCLCPNLQVGQSYLFITRSHQVPYGDRMELLLDTHSVVLKWRESWRRRLSKFVRRAARESCD 715
BLAST of Netrin-1 vs. TrEMBL
Match: A0A4Z2D9H4 (Netrin-A OS=Schistosoma japonicum OX=6182 GN=EWB00_003107 PE=4 SV=1) HSP 1 Score: 449.899 bits (1156), Expect = 8.210e-141 Identity = 261/684 (38.16%), Postives = 367/684 (53.65%), Query Frame = 3
Query: 747 ISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEI-LPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM----NDTLIKWITITDLRITLSRFD--------DQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDK-------------------------SMSKVYYGVSDLSVGGRCQCYGHSNKCIIN----------NDG-------NIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKT---YDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQ---YAVPLWISHEEVR-----CDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCE 2600
+ V+YE ++ C G+ C+PPF NIA+ I TS+CG+ ++IC +Y R C ICD+ K + LTD N TCW SG V + VN++++ K FEV+Y++LQ C +LPDSI +YKS D G W PWQY+S +C +AF LP + E Q L C L +G++ +I+ FS+TIGR + LI W+T+TDLRI+L RF D + + G K R N+ F +N S S V++ SDLS+GGRC+C GH+N+C+ + NDG + CDC+HNTEG DC++C G+ D W R + + CKRC CNLHS C F +Y+ + + SGGVC+ CQHNT G +CH C GYYRDWTKP+SHD C +C+CH +GS CD+K GQC CK GVIG+ C++C+ GY QTR PC+K Y + S M ++ C PC+ +KRIRFKKFCR ++VF G+I+S+ +HG ++R E+ I+ WR++G + + + Y V L I + C CPN+ +G+SYL + + + R ELLLDS++V+L+WR SW RRL KF +A E C+
Sbjct: 43 VKVIYEATRSVCYTKGQAIECSPPFTNIAESIDIKATSTCGQFGQSEEIC---RYVLGQ--RKCDICDSSEK---FGTHLLTDRHQMNNETCWISGSVLPG---DTVNLTLSLGKRFEVYYISLQPCGQLPDSIALYKSSDFGITWKPWQYFSTDCYRAFRLPTSNEHNAQISLANIQEVLCVALKSPDIHDAIGKSSNIIAFSTTIGRPSTQPWSSALIDWMTMTDLRISLMRFPEHREEVQHDSNGLFLNPGLLKPSKVFRVSGSPNIGGFGINPALSETGALDMSQHLYQSDMHYAKTPNSKSPVHFSFSDLSIGGRCKCNGHANRCVRDRIVSTSSTKENDGLAKSQWGPLRCDCQHNTEGTDCERCSSGYLDRPWARGTSESANECKRCDCNLHSNSCIFSNQLYLMSMKVSGGVCQDCQHNTVGRRCHNCATGYYRDWTKPVSHDQVCLECRCHPIGSIANQHCDRKTGQCPCKPGVIGQACNRCQDGYKQTRLPDAPCIKAMEHYAHRRKENDQTSHPTKSQMSRLEPDTNCPPCERSKKRIRFKKFCRCEAVFRGIIKSRTIHGDLMRLEVGIQNTWRITGAAEHLLPKTASPNLPAYRVWLRIKNNSADKRHSFCLCPNLLVGQSYLFITRSHQVPYGDRMELLLDSQSVILRWRESWRRRLSKFVRRAARESCD 715
BLAST of Netrin-1 vs. TrEMBL
Match: A0A4S2M819 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002075 PE=4 SV=1) HSP 1 Score: 436.417 bits (1121), Expect = 5.123e-136 Identity = 250/669 (37.37%), Postives = 355/669 (53.06%), Query Frame = 3
Query: 747 ISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEI-LPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMND----TLIKWITITDLRITLSRFDDQMSSYFDYGKYFLL-----------------KHRRGRDILNMSTFSVNDKSMS-----KVYYGVSDLSVGGRCQCYGHSNKCI-----------INNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYD-IIESSQTKKSDLNSKYMDMP-NTES--ECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFIS-EISQEQYAVPLWISHE---------EVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKC 2597
I V+YE+ ++ C G+ C PPF NIA+ A + TS+CG + C + C C ++ K + LTD N T W SG V +NI+++ K FEV+YV+LQ LPD+I +YKS D GK W PWQY+S +C +AF LP + E Q C L + + G++ ++ FS+TIGR + L+ W+T+TDLR++L+RF D LL K++ L MS + S +++ SDL++GGRC+C GHSN+C+ G + CDC+HNT G DC+KC G+ D W RA++ CKRC CNLHS C+F + +Y+ + + SGGVC+ CQHNT G +CH C +GYYRDWTKP+SH+ C +C+CH +GS CD+K GQC CK GVIG+ C++C+ GY QTR PCV+ + +T + + P NTE +C PC R+RIRFKKFCRR++VFMG +ES G RFE++I+E WRV G + + + S P+WI + +RC CP + G SYL + H +R EL+LD ++++ WR SW RRL KF +A + +C
Sbjct: 44 IRVVYEDVRSPCHSEGRASQCMPPFTNIAEGAPVVATSTCGASDKTEKFCKQQVDATGRIQWRCEQCTSEDK---FPTHHLTDRHQMVNETYWVSGAVLRGQT---INITLSMGKTFEVYYVSLQPYGRLPDAIALYKSSDFGKTWHPWQYFSTDCFRAFRLPTSNEHNAQISAANIQEVLCVALKSSEDNEPYGRSLKVIAFSTTIGRPSSQPWSAALVDWMTMTDLRVSLTRFSDLADMTQHDASGLLLTPNLLSPAEVFRVGEVEKNKMSAGTLGMSRHHFQSDAASFMPDKGIHFAFSDLAIGGRCKCNGHSNRCVRDRLVDAAGKETGEWGPLRCDCQHNTAGIDCEKCAPGYLDRPWARATRELANECKRCDCNLHSLTCEFSQQIYLMSSKTSGGVCQNCQHNTVGRRCHHCASGYYRDWTKPVSHEQVCLECRCHPIGSVANEPCDRKSGQCPCKPGVIGQACNRCEEGYKQTRLSDHPCVRVMEHFAYRRKTVPPPVAASSHHQPINTEPHLKCPPCKPHRRRIRFKKFCRREAVFMGKVESYRAEGDKTRFEIRIRETWRVDGAAGRLLPKKASHSLPPFPVWIQSQLIGGDNGNPAIRCLCPELKTGESYLFFTQPYQIPHGNRMELMLDPSSIIIPWRESWRRRLNKFVRRAAKNRC 706
BLAST of Netrin-1 vs. TrEMBL
Match: A0A5K3F9D3 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 435.261 bits (1118), Expect = 2.345e-135 Identity = 251/728 (34.48%), Postives = 376/728 (51.65%), Query Frame = 3
Query: 753 VLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEI-LPDDICPHWKYYSSNHFRD-CSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDT----LIKWITITDLRITLSRFDDQMSSYF---DYGKYFLLKHRRGRD-----------------------------------ILN------------MSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCI-------------INNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYD-IIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQ--FISEISQEQYA-VPLWIS---------HEEVRCDCPNISLGRSYLILMK-YKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFLQKKSKIKHNRINRVGKNKRSFLLTKN 2687
V+YE+ + C K Y CTPPF NIA+ + TS+CG+ + +C W + + C CD+ + + + LTD N TCW SG V + VN++++ K FE+FY++LQ C LPDSI +YKS D G+ W PWQY+S +C +AF LP + E Q C + K GQ +++ FS+TIGR + + LI W+T+TDL+I+LSRF + S G ++ HRR R LN ++T ++ VY+ SD++VGGRC+C GH+N+C+ I G + CDC+HNT GADC++C G+ D W RA+ + CK C+CNLHS C F + Y+ + + SGGVC C+H+T G +CH C G+YRDWTKP+SH + C KC+CH +GS CD+K GQC CK GV G+ C++C GY QTRS + PCVK D ++ + +S + + P + C PC++ KR RFKKFCRR +VF + S+E G++VR ++I +VWR G ++Q + + + Q +PLW+ C CP + +SYL + + Y+I H R ELLLD ++ +L W +W RRL +F + +C+ S ++++ ++R+ + +N
Sbjct: 36 VIYESPNSVCYADNKAYLCTPPFTNIAEGIPVVATSTCGQGGRAERVCKSWTSQNGQKRQTYCETCDSRKAATSRGAERLTDRHITSNQTCWVSGKVAPG---STVNLTLSLGKRFEIFYISLQPCGPLPDSIALYKSSDFGRTWKPWQYFSTDCYRAFGLPTSSEHNAQISSANIQEVLCVAIKPPVKYNAQGQVSNVIAFSTTIGRPTSQSWSPALIDWMTMTDLQISLSRFPARRKSRTVERSGGDNTVVLHRRDRSSGQRRVPQKAPVFRLGGGRLFHQGAELEEMQADGTTLNATASTATNARNEVNTHEIHHDEDDAVYFAFSDIAVGGRCKCNGHANRCVRDRIVEKNAAGEEIVTWGPLRCDCQHNTVGADCERCAPGYLDRPWARATNEDANECKACECNLHSNSCTFSQYFYLLSKKVSGGVCEDCRHHTTGEKCHQCMEGFYRDWTKPISHPMVCLKCQCHPIGSIGSRPCDRKTGQCHCKTGVTGQTCNRCLDGYKQTRSKITPCVKAVDALVFAGSATRSSPQTSIVGQPTADDACPPCEKNNKRFRFKKFCRRQAVFRATVISQEARGELVRLVIRIHDVWRNKGSLAQRYLPAHVRRNQAPIIPLWVPLTKKPSTSRESHAVCVCPRFKIDQSYLFISQVYEIPFH-ERNELLLDQKSTILPWVENWRRRLMRFAIRQERGRCDAV----SDDPYSQVRITPDHRRNLIRPRN 755
BLAST of Netrin-1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]) HSP 1 Score: 352.443 bits (903), Expect = 4.558e-110 Identity = 213/612 (34.80%), Postives = 314/612 (51.31%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINND-GNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
HG C P F+N A ++ +S+CG P C K R C CD + LTD N N TCW S Q +V ++++ K FEV YV++QFCS+ PDS+ I+KS D GK W+P+Q+YS C+K FN P Q E C D + + + G ++ FS+ GR + L W+T TD+R+T SR ++ D+ ++Y VSDL VGGRC+C GH+++C+ D G +VCDCKHNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C GYYRD +KP+SH ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K I + T + + D +S CK K K K + +V + +++S + G+ +F + I V++ Q S I + LW+ ++V C CP I G+ YL+L + + ++ D ++++QWR +W RRL+KFQ + + KC+K
Sbjct: 41 HGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQDK--GEEGARTCHTCDASDPKRAHPGSYLTDLNNPHNLTCWQS-ETGVQALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRPNRAAITKQNEQEA----VCTDAHADGRPLSGG----LVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSR---------------------------LTAPGEPDEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIK---IPVAPPTTTASSPEEPADC---DSYCKASKGKLKINMKKYCKKDYAVQVHILKSDKA-GEWWKFTVNIISVYK------QGESRIRRGDQL--LWVRAKDVACKCPKIKTGKKYLLLGNDE--DSPGQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 596
BLAST of Netrin-1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]) HSP 1 Score: 353.984 bits (907), Expect = 1.605e-108 Identity = 212/612 (34.64%), Postives = 314/612 (51.31%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINND-GNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
HG C P F+N A ++ +S+CG P C K R C CD + LTD N N TCW S Q +V ++++ K FEV YV++QFCS+ PDS+ I+KS D GK W+P+Q+YS C+K FN P Q E C D + + + G ++ FS+ GR + L W+T TD+R+T SR ++ D+ ++Y VSDL VGGRC+C GH+++C+ D G +VCDCKHNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C GYYRD +KP+SH ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + + T S + + +S CK K K K + +V + +++S + G+ +F + I V++ Q S I + LW+ ++V C CP I G+ YL+L + + ++ D ++++QWR +W RRL+KFQ + + KC+K
Sbjct: 218 HGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQDK--GEEGARTCHTCDASDPKRAHPGSYLTDLNNPHNLTCWQS-ETGVQALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRPNRAAITKQNEQEA----VCTDAHADGRPLSGG----LVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSR---------------------------LTAPGEPDEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIK-IPVAPPTTTASSP-----EEPADCDSYCKASKGKLKINMKKYCKKDYAVQVHILKSDKA-GEWWKFTVNIISVYK------QGESRIRRGDQL--LWVRAKDVACKCPKIKTGKKYLLLGNDE--DSPGQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 773
BLAST of Netrin-1 vs. Ensembl Cavefish
Match: ntn1b (netrin-1-like [Source:NCBI gene;Acc:111191060]) HSP 1 Score: 343.969 bits (881), Expect = 1.612e-106 Identity = 211/610 (34.59%), Postives = 311/610 (50.98%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINND-GNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKC 2597
+G+ C P F+N A ++ +S+CG C + R+C CD + LTD N N TCW S Y QH N V ++++ K FEV YV+LQFCS P+S+ IYKS D GK W+P+Q+YS C+K FN P Q E + + D+ A ++ FS+ GR + L W+T TD+R+T SR H G + + S + + +Y VSDL VGGRC+C GH++KC+ + D G +VC+CKHNT GA+CD+CK +D W+RA+ C C CNLH++ C+F +Y +G++SGGVC C+HNTAG CH+C GYYRD TK +SH ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K I +S T + D +S CK K K K + +V + V++ + G+ +F + I V++ + ++ LW+ ++V C CP I G+ YL+L R + ++ D ++++ W+ W RRL+KFQ + KC
Sbjct: 61 NGQPRRCIPDFVNAAFGKEVRASSTCGAQTAARYCVVTER-GEERSRECHTCDAADPKKAHPAAYLTDLNNPHNLTCWQS-ESYVQHPQN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCKKMFNRPSRAAITKQNEQEAVCTDSHTDMRP--------LAGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRL-----------------HTFGDENEDDSELARDS-----YFYAVSDLQVGGRCKCNGHASKCVKDRDGGGLVCECKHNTAGAECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMTKAISHRRACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIK---IPVASPTATYTSAEEPTDC---DSHCKASKGKMKVTMKKYCKKDFAVQVHVLKGDKA-GEWWKFTINIISVYKQGEHRIRRGDQL--------LWVRAKDVACKCPKIKPGKKYLLLGS-DDDDSRGQSGVVADKGSLLIPWKDLWARRLRKFQQRDKRGKC 620
BLAST of Netrin-1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]) HSP 1 Score: 264.233 bits (674), Expect = 3.199e-77 Identity = 146/393 (37.15%), Postives = 202/393 (51.40%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINND-GNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACK 1946
HG C P F+N A ++ +S+CG P C K R C CD + LTD N N TCW S Q +V ++++ K FEV YV++QFCS+ PDS+ I+KS D GK W+P+Q+YS C+K FN P Q E C D + + + G ++ FS+ GR + L W+T TD+R+T SR ++ D+ ++Y VSDL VGGRC+C GH+++C+ D G +VCDCKHNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C GYYRD +KP+SH ACK
Sbjct: 218 HGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQDK--GEEGARTCHTCDASDPKRAHPGSYLTDLNNPHNLTCWQS-ETGVQALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRPNRAAITKQNEQEA----VCTDAHADGRPLSGG----LVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSR---------------------------LTAPGEPDEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKACK 572
BLAST of Netrin-1 vs. Ensembl Cavefish
Match: ntn1b (netrin-1-like [Source:NCBI gene;Acc:111191060]) HSP 1 Score: 262.307 bits (669), Expect = 1.208e-76 Identity = 148/394 (37.56%), Postives = 207/394 (52.54%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINND-GNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKK 1949
+G+ C P F+N A ++ +S+CG C + R+C CD + LTD N N TCW S Y QH N V ++++ K FEV YV+LQFCS P+S+ IYKS D GK W+P+Q+YS C+K FN P Q E + + D+ A ++ FS+ GR + L W+T TD+R+T SR H G + + S + + +Y VSDL VGGRC+C GH++KC+ + D G +VC+CKHNT GA+CD+CK +D W+RA+ C C CNLH++ C+F +Y +G++SGGVC C+HNTAG CH+C GYYRD TK +SH ACK+
Sbjct: 61 NGQPRRCIPDFVNAAFGKEVRASSTCGAQTAARYCVVTER-GEERSRECHTCDAADPKKAHPAAYLTDLNNPHNLTCWQS-ESYVQHPQN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCKKMFNRPSRAAITKQNEQEAVCTDSHTDMRP--------LAGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRL-----------------HTFGDENEDDSELARD-----SYFYAVSDLQVGGRCKCNGHASKCVKDRDGGGLVCECKHNTAGAECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMTKAISHRRACKE 421 HSP 2 Score: 76.6406 bits (187), Expect = 5.532e-14 Identity = 73/290 (25.17%), Postives = 124/290 (42.76%), Query Frame = 3
Query: 1758 RCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYY-RDWTKPLSHDL-ACKKCKCHAVGST---NVN----SCDKKLGQCF-CKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKC 2597
RC+CN H+ C +++ GG+ +C+HNTAG +C C +Y R W + + + C C C+ N+ S + G C C+ GR C CK GY R M K E + + + + +S CK K K K + +V + V++ + G+ +F + I V++ + ++ LW+ ++V C CP I G+ YL+L R + ++ D ++++ W+ W RRL+KFQ + KC
Sbjct: 301 RCKCNGHASKCVKDRD--------GGGLVCECKHNTAGAECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYY--RDMTKAISHRRACKEIPVASPTATYTSAEEPTDCDSHCKASKGKMKVTMKKYCKKDFAVQVHVLKGDKA-GEWWKFTINIISVYKQGEHRIRRGDQL--------LWVRAKDVACKCPKIKPGKKYLLLGSDDD-DSRGQSGVVADKGSLLIPWKDLWARRLRKFQQRDKRGKC 570
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009682.1 (pep scaffold:Pmarinus_7.0:GL479835:738:11671:-1 gene:ENSPMAG00000008750.1 transcript:ENSPMAT00000009682.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 169.859 bits (429), Expect = 7.203e-47 Identity = 109/345 (31.59%), Postives = 163/345 (47.25%), Query Frame = 3
Query: 1086 KNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGY-LQTRSMLKPCV 2099
K F++ YV L+F + P+S IYK W P+QYYS +C+ + + + +P C D G + FS+ GR + L W+T T++R+TL+R + +G H K + YY +SD +VGGRC+C GH+++C+ N G + C C+HNT GADC+KC ++D W RA+ + C C CN + C F+ +Y TG GG C C+ NT G C C +YR S C C C+ VGS + CD++ G+C CK+GV+G +CD+C G+ + +PC
Sbjct: 2 KAFDITYVRLKFHTSRPESFAIYKRASMDGPWTPYQYYSGSCEPTYG---KRNRGFLRSGDDEQTPLCTDEFSDISPLTGGN----VAFSTLEGRPSAYNFDNSPVLQDWVTSTEIRVTLNRLNT-------FGDEVFNDH----------------KVLRSYYYAISDFAVGGRCKCNGHASECVKNELGALACKCRHNTMGADCEKCLPLYNDRPWHRATSESANECTLCDCNGRADECYFDPELYRATGH--GGHCTNCRDNTDGKTCERCLENFYR-----RSASEHCLPCNCNPVGSYS-RQCDEQ-GRCSCKQGVMGERCDQCLPGFHSMDEAGCRPCT 307
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004606.1 (pep scaffold:Pmarinus_7.0:GL477874:5526:15188:-1 gene:ENSPMAG00000004198.1 transcript:ENSPMAT00000004606.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 115.546 bits (288), Expect = 1.304e-29 Identity = 70/223 (31.39%), Postives = 104/223 (46.64%), Query Frame = 3
Query: 1086 KNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGR------KMNDTLIK-WITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERAS 1733
K F++ YV L+F + P+S IYK W P+Q+YS C++ F LP + +L F GN+ FS+ GR ND L + W+T TD+R++L R + F + K + YY VSDL+VGGRC+C+GH+++C +DG +VC C+HNT G DC++C + W +AS
Sbjct: 4 KAFQITYVRLRFHTSRPESFAIYKRTSPASPWQPYQFYSGTCERTFGLPSRGFLRAGDEERTALCSDEFSDISPLTGGNVA-------FSTLEGRPGALAFDGNDKLQQEWVTATDVRVSLRRLNTFGDEVFG-----------------------DPKVLRSYYYAVSDLAVGGRCKCHGHASECGRGSDGRLVCRCQHNTTGDDCERCLPSHNSRPWAQAS 196
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004614.1 (pep scaffold:Pmarinus_7.0:GL477874:5547:15173:-1 gene:ENSPMAG00000004198.1 transcript:ENSPMAT00000004614.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 112.079 bits (279), Expect = 1.546e-28 Identity = 64/213 (30.05%), Postives = 100/213 (46.95%), Query Frame = 3
Query: 1092 FEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERA 1730
F++ YV L+F + P+S IYK W P+Q+YS C++ F LP + +L F GN+ + F ST ++ +W+T TD+R++L R + F + K + YY VSDL+VGGRC+C+GH+++C +DG +VC C+HNT G DC++C + W +A
Sbjct: 1 FQITYVRLRFHTSRPESFAIYKRTSPASPWQPYQFYSGTCERTFGLPSRGFLRAGDEERTALCSDEFSDISPLTGGNVAFSTLEGLFHST--GPLSSATQEWVTATDVRVSLRRLNTFGDEVFG-----------------------DPKVLRSYYYAVSDLAVGGRCKCHGHASECGRGSDGRLVCRCQHNTTGDDCERCLPSHNSRPWAQA 188
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008925.1 (pep scaffold:Pmarinus_7.0:GL476496:30277:70426:-1 gene:ENSPMAG00000008054.1 transcript:ENSPMAT00000008925.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 117.472 bits (293), Expect = 5.810e-27 Identity = 98/363 (27.00%), Postives = 155/363 (42.70%), Query Frame = 3
Query: 1092 FEVFYVALQFC-SELPDSITIYKSHDNGKKWIPWQYYS---KNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDT----LIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGN-IVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKS-------GGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSC-----------DKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCV 2099
F+V YV ++ S P + + +S D G + PWQYYS C + + PT P+ + + + + + L A + S GR D L+ + + +R+ L R + L HR R++ + T + YY + D+SVGG C C GH++ C N D + C C+HNT G +C C G++ +W + N +C++C C+ ++ C ++ V S GGVC C NTAG C C +G+YR + C+ C+C GS + C D GQC C+ G G +C++C Y + KPC+
Sbjct: 3 FQVAYVIVKAANSPRPGNWILERSLD-GATYHPWQYYSVSDSECLTRYGITPTVGNPVYRRDDEVICTSYYVVL-------LMLARGKIHTSLINGRPSADDPSPKLLDFTSARYIRLRLQRIRTLNA------DLMTLSHRDPREVDPIVT--------RRYYYSIKDISVGGMCICSGHASTCPWNEDTQKMECQCEHNTCGENCQHCCPGYNQRRWRPGTINNGNTCEKCNCHGKTEDCYYDAEVDRTNRSLSVHGRFSGGGVCVNCSANTAGTNCETCRDGFYRPTGVLPNDPYPCRLCQCDPQGSLS-QVCIKDEKHADPEKDLSPGQCLCRPGFAGERCERCAFAY-RGYPDCKPCL 341 HSP 2 Score: 78.9518 bits (193), Expect = 3.402e-15 Identity = 50/147 (34.01%), Postives = 76/147 (51.70%), Query Frame = 3
Query: 1683 CDKCKEGFHDLQWERAS------KLNPF-SCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGY--LQTRSMLKPC 2096
CD+C G+ L+ ER + +P SC+RC+CN + + + +TGQ C +C+ TAG C C +G+Y D T C+ C+CH G+T CD+ GQC C+ V+GR C++C IG+ L + + PC
Sbjct: 704 CDQCLPGYIGLRCERCADDFFGEPSSPGGSCRRCECNGNEEAWGGGRVCDARTGQ-----CLRCRERTAGFHCERCADGFYGDATG----TGGCQPCQCHPEGAT-APQCDRINGQCPCRPSVVGRTCEQCAIGFYGLSSGAGCSPC 840 HSP 3 Score: 62.7734 bits (151), Expect = 3.959e-10 Identity = 51/184 (27.72%), Postives = 77/184 (41.85%), Query Frame = 3
Query: 1590 RCQCYGHSNKCIINND----------------GNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLH---SQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGY--YRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTR 2078
+C C+G + C + + G + +C NT G +C+ C++GF+ + +P+ C+ CQC+ SQ C ++ S G C C+ AG +C C Y Y D CK C C G TN + C + C CKE V G CD+C+ G+ R
Sbjct: 212 KCNCHGKTEDCYYDAEVDRTNRSLSVHGRFSGGGVCVNCSANTAGTNCETCRDGFYRPTGVLPN--DPYPCRLCQCDPQGSLSQVCIKDEKHADPEKDLSPGQC-LCRPGFAGERCERCAFAYRGYPD----------CKPCLCSMAGGTNDDPCSEP---CVCKERVEGEHCDRCRAGFYDLR 379 HSP 4 Score: 58.5362 bits (140), Expect = 6.297e-9 Identity = 48/167 (28.74%), Postives = 67/167 (40.12%), Query Frame = 3
Query: 1590 RCQCYGHSNKCIINNDGNIVCD--------CKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGY 2066
RC+C G+ G VCD C+ T G C++C +GF+ C+ CQC+ + + G C C+ + G C C G+Y LS C C CH VG+ V +C G+C C GV GR CD+C G+
Sbjct: 736 RCECNGNEEA----WGGGRVCDARTGQCLRCRERTAGFHCERCADGFY------GDATGTGGCQPCQCH--------PEGATAPQCDRINGQC-PCRPSVVGRTCEQCAIGFYG-----LSSGAGCSPCPCHPVGTAGV-ACSAD-GRCHCWPGVEGRSCDRCTSGH 876 HSP 5 Score: 55.0694 bits (131), Expect = 8.808e-8 Identity = 45/170 (26.47%), Postives = 67/170 (39.41%), Query Frame = 3
Query: 1557 YYGVSDLSVGGRCQCYGHSNKCII-NNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIG 2063
+YG+S + C C+ + + DG C C EG CD+C G + + C C C+ + HC E + C NT G +CH C + ++ ++ C+ C C A S CD+ GQC C +G GR C +C G
Sbjct: 828 FYGLSSGAGCSPCPCHPVGTAGVACSADGR--CHCWPGVEGRSCDRCTSGHYGFKEG--------GCTPCNCSHTNHHCDQETGRCL------------CPPNTEGTRCHRCIDDHWG-----VNPHAGCRACNCSAAHSRGAR-CDEASGQCSCLDGYGGRTCGECAQG 969 HSP 6 Score: 53.1434 bits (126), Expect = 3.170e-7 Identity = 47/150 (31.33%), Postives = 65/150 (43.33%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNL-HSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGS----------TNVNSCDKKLGQCFCKEGVIGRKCDKCKIG 2063
C C NTEG C +C D W +NP + C+ C C+ HS+ + ++ +GQ S C G C C G W P AC+ C+CH G+ ++ CD++ GQC CKE V G +CD C G
Sbjct: 903 CLCPPNTEGTRCHRCI----DDHW----GVNPHAGCRACNCSAAHSRGARCDE----ASGQCS------CLDGYGGRTCGECAQGR---WGYP-----ACRPCECHPEGTRANTCPAPPTGSLCGCDERTGQCACKENVGGTRCDACLPG 1026
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007784.1 (pep scaffold:Pmarinus_7.0:GL477336:382472:417638:1 gene:ENSPMAG00000007035.1 transcript:ENSPMAT00000007784.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 100.523 bits (249), Expect = 8.974e-22 Identity = 69/278 (24.82%), Postives = 124/278 (44.60%), Query Frame = 3
Query: 1062 VNISIAFKK-NFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSRF--DDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDG-NIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTG---QKSGGVCRKCQHNTAGN 1874
V +SI + +++VFYV +QF S P+ + I + G W+ WQ ++K+C +N+ ++ P LE S C ++ +P S + N T +LR + F + ++ + +L R + ++ + + Y+ VS++ V GRC+C+GH+ +C + +C + NTEG +C+ C+ F D W N +C+ C C + C++E + G + GGVC+ C NT G+
Sbjct: 107 VAVSIELRGGSYQVFYVIVQFLSPQPEGVRIQRRPAAGSPWVDWQVFAKDCVSMYNM--SKNGP----LEKPDSVNCLQFPRE------------VPLS-----RGNVTFSVLTPEPNLRPGYNAFYATPALQAFVLAAEVRVLLEGRLLGVAGVAGGPL------RPYHAVSEVIVSGRCECHGHAERCDSSTTPYRCLCSAQSNTEGPNCELCRPLFRDKPWRAGDTRNQNACRPCLCYGRALSCRYEAILDPHPGLHWRGGGGVCQDCTQNTTGS 355 HSP 2 Score: 63.5438 bits (153), Expect = 1.855e-10 Identity = 41/145 (28.28%), Postives = 60/145 (41.38%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLA-CKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRS 2081
C C G C C+ GF+ L+ + + C+ C C+ E+ + G C H G +CH C + YY + +L C++C C GS + SC GQC CK +GR+CD C G R+
Sbjct: 658 CACLPGWAGRRCSTCQAGFYRLEGDASG------CRPCDCH--------ERGSAHAACDGNSGQCACTSHTVGGRRCHRCAHSYYG-----FAQELGRCRECACSTAGSLD-TSCHPDTGQCSCKALAMGRRCDACTHGASHLRA 782
BLAST of Netrin-1 vs. Ensembl Nematostella
Match: EDO36836 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHI5]) HSP 1 Score: 293.893 bits (751), Expect = 5.999e-89 Identity = 186/597 (31.16%), Postives = 290/597 (48.58%), Query Frame = 3
Query: 807 CTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQA--ESILPFSSTIGR----KMNDTLI--KWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESE-CKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKF 2570
C P F ++A + V+ +CGE CP C CD + + K LTD N+ N TCW + PV ++ +V + ++F K +++ YV+LQFC PDS+ IYKS D GK W +Q+YS C+K + E E + +L DG+L + + FS+ GR KM+ + + +W+ TD+++ + + + R RD L YY VS+ +VGGRC C GH+++C+ + +G VCDCKHNT G DC C+ F+D W A+ + CK C CNLH++ C F ++ +G +SGGVC KC+HNTAG CH+C G+Y+D K ++H C++C CH GS C++ GQC CKEGV+GR CDKC GY T+S + PC++T +++ S ++ P + + C C +++ V K++ VR + I ++ K S+ + Y +WI + RC CP + GRSY I + + ++L+ R+V+L W +R+ +F
Sbjct: 15 CQPAFHDLAYNKDVYVSHTCGE-KSRRFCPPMSVRGRT---ACGFCDERNAKTSHPAKYLTDVHNENNVTCWQADPVQSRE---NVTLILSFGKTYDITYVSLQFCGIRPDSMGIYKSMDYGKSWQAYQFYSSRCEKMYGRVTNGEIS-PENEQVALC----------TDGHLLRPLYGGRIAFSTLEGRPSASKMDYSAVMQEWVMATDIKVEFN---------------MISRSARPRDSL---------------YYAVSEFNVGGRCHCNGHASECVSDRNGRQVCDCKHNTVGVDCGACRPFFNDRPWRPATHHSANECKMCNCNLHARTCVFSMELFKLSGGRSGGVCVKCRHNTAGRYCHYCREGFYKDPNKHITHIKVCRQCNCHPHGSRG-RVCNQSTGQCPCKEGVVGRSCDKCAPGYKSTKSNIVPCIETPNVVMSQES----------STPRSRDQGCSQCRRVPLKVKRFCRKDFALKVTVVRVEKKLPNSWVRATVNINTLF----KRSRTRRVRRGDGY---VWIKKRDFRCRCPKLKPGRSYFIAGNLR--GQSRKRSIVLNGRSVVLPWNEKLLKRIYRF 543
BLAST of Netrin-1 vs. Ensembl Nematostella
Match: EDO36523 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF3]) HSP 1 Score: 190.66 bits (483), Expect = 1.724e-49 Identity = 130/450 (28.89%), Postives = 213/450 (47.33%), Query Frame = 3
Query: 789 HGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRK------MNDTLIKWITITDLRITLSRFDDQMSSYFD--YGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKC----IINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWT-KPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQ-TRSMLKPC 2096
G+ C P F N A ++ ++CG+ P C ++C +C++ + +TD + N T W+ ++ V +++ K+++V Y+ ++F S P+S+ IYK KWIP+QY+S C+K + + T + +L F GN+ FS+ R + L +W+T +RI L R M+++ D +G +L+ YY + DLS+GGRC+C GH+++C + + + C C+H+TEG DC++CK ++D W RAS N C RC CN ++ C F++ +Y +TG GG C+ C+ NT G C C +YR + +P C C C+ VGS ++ C+ + GQC CK GV G KCDKC+ Y +++ +PC
Sbjct: 25 QGRAQRCMPQFGNAAFGKRVISNNTCGDP-PKKFCVQTGVLEVR--KECEMCNSSDPALEHPALKITDIKDDTNRT-WWQSETLLENPDKPVTLTLDLGKSYDVSYIRIRFRSPRPESMAIYKKTTPSSKWIPYQYFSATCEKTYGV-TTNGIVDPRNQQVALCTDAFSTITPLTGGNVA-------FSTLEDRPDAYNFDNSPALQEWVTAVAVRIHLRR----MNTFGDEVFGDPNVLR---------------------SYYYAIIDLSIGGRCKCNGHASECEETRLWDGQTRLQCKCQHDTEGVDCERCKPLYNDRPWARASSRNANECVRCNCNGLAESCVFDEALYRQTGH--GGRCQNCKQNTDGPNCERCKENFYRKTSLEP------CVACGCNPVGSVSLQ-CNSE-GQCRCKPGVTGIKCDKCQANYFGFSQTGCRPC 427 HSP 2 Score: 85.5001 bits (210), Expect = 6.458e-17 Identity = 54/164 (32.93%), Postives = 74/164 (45.12%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHA-VGSTNVNSCDKKLGQCF-----CKEGVIGRKCDKCKIGY 2066
CQCYGHS+ C + C+CKHNT G CDKC +G+ + ++ P CK+C C ++ + NV VC C GN C C +GYY D C+KC C + + SCD+ G C + G I +C+ C IGY
Sbjct: 704 CQCYGHSDTC---DPVTGKCNCKHNTTGIRCDKCIDGY----YGNPTQGTPDDCKKCPCKFGTRCIQIGANV----------VCTDCPEGHVGNLCDMCQDGYYGDPMGKRGAPTTCQKCNCSGNIDPNAIGSCDRLTGDCLKCIHNTRNGPIS-QCELCAIGY 849 HSP 3 Score: 60.4622 bits (145), Expect = 3.438e-9 Identity = 55/203 (27.09%), Postives = 78/203 (38.42%), Query Frame = 3
Query: 1638 GNIVC-DCKHNTEGADCDKCKEGFH-DLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAG---NQCHFCDNGYYRDWT------------------KPLSHDL-------------------------------------ACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGY 2066
N+VC DC G CD C++G++ D +R + P +C++C C+ + + N + + + G C KC HNT +QC C GYY + T P HD C+ C C GS N N+C GQC CK GV GR+CD+C I +
Sbjct: 766 ANVVCTDCPEGHVGNLCDMCQDGYYGDPMGKRGA---PTTCQKCNCSGN-----IDPNA-IGSCDRLTGDCLKCIHNTRNGPISQCELCAIGYYGNATHYPKPQCKACECYVQGTVSPPGHDPTLPFPCDDKGRCTCLPNVSGDKCDTCRPEYWNVASGKGCEPCNCDTTGSWN-NTCSVTTGQCHCKPGVTGRRCDQCSIDH 958 HSP 4 Score: 55.8398 bits (133), Expect = 8.818e-8 Identity = 52/184 (28.26%), Postives = 74/184 (40.22%), Query Frame = 3
Query: 1593 CQCY--------GHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIE 2120
C+CY GH D C C N G CD C+ + W AS C+ C C+ + + TGQ C C+ G +C C +Y +L C C C+ GS NV +CD++ G C C+ GV+G KCD C+ + + C YD+I+
Sbjct: 864 CECYVQGTVSPPGHDPTLPFPCDDKGRCTCLPNVSGDKCDTCRPEY----WNVASGK---GCEPCNCDTTG---SWNNTCSVTTGQ-----CH-CKPGVTGRRCDQCSIDHY------AFSELGCLACNCNLQGSLNV-TCDEQ-GVCQCRPGVLGIKCDSCQENFHNLTAGCIACPPCYDVIQ 1023 HSP 5 Score: 55.4546 bits (132), Expect = 1.081e-7 Identity = 47/146 (32.19%), Postives = 67/146 (45.89%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKC------KCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGY 2066
C C +G +C++CK+G+ +A + ++ C CQC HS C G C C+HNT G +C C +GYY + T+ D CKKC +C +G+ NV D C EG +G CD C+ GY
Sbjct: 670 CSCPKEYKGNNCEQCKDGYT----RQAGSTDRYAQCVPCQCYGHSDTC-----------DPVTGKC-NCKHNTTGIRCDKCIDGYYGNPTQGTPDD--CKKCPCKFGTRCIQIGA-NVVCTD-------CPEGHVGNLCDMCQDGY 789
BLAST of Netrin-1 vs. Ensembl Nematostella
Match: EDO39502 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9X8]) HSP 1 Score: 179.874 bits (455), Expect = 4.960e-46 Identity = 122/441 (27.66%), Postives = 200/441 (45.35%), Query Frame = 3
Query: 828 IAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYN----------QHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNL--GQAESILPFSSTIGRKMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIV-------CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKK--------LGQCFCKEGVIGRKCDKCKIGYL 2069
+ + KI +S+CG P++ C + + DC ICD S T+P QF+H + ++ ++G +V + + + F ++ ++F + P + I +S D GKKW ++Y+S +C K F P E + ++ + + + +G + +S +P + K+ + L IT++RI ++ H G D+L+ + K YY V DL + G C CYGH+ +C+ C+C HNT G +C++C++G+ D+ W A NP C++C CN H+ C+F+ VY +G SGGVC+ C+HNT G C C +Y+D +K S AC C C G N C+ K G+C CK V G +CD+CK G+
Sbjct: 32 VGRENKIYASSTCGLRGPEEYC---VVSNLQDYGDCHICD--------SRPYQTNP--QFSHVPKYMLSSFDGRKKDEWWQSENGRENVYLQLDLESEFHFTHLIMRFRTFRPAGMVIERSWDYGKKWQIYRYFSADCDKIFPGIPKGE---PKDIDDVICTNKYSTVEPSTNGEVIFRALKSQIPIKNAYSSKVQNLL----KITNIRINFTKL-----------------HTLGDDLLDPRP-----EIKRKYYYAVYDLVIRGSCSCYGHAEQCLPEPGQPTTPGMVYGRCNCTHNTTGKNCERCQDGYFDVPWRPADADNPNECRKCNCNGHAVKCRFDPAVYQASGNVSGGVCQDCEHNTVGRNCERCKPLHYQDPSKKFSDPDACIACNCDPTGGVNGGECEAKNDPAAGLVAGRCICKRNVGGVRCDRCKAGFF 430 HSP 2 Score: 81.2629 bits (199), Expect = 1.549e-15 Identity = 63/210 (30.00%), Postives = 86/210 (40.95%), Query Frame = 3
Query: 1593 CQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGV-CRKCQHNTAGNQCHFCDNGYYRDWTKPL---------------------------------SHDLACKKCKCHAVG---------------STNVN---SCDKKLGQCFCKEGVIGRKCDKCKIGY 2066
C+CYGH++ C N + DC+HNT G +C+ C GF+ + A+K P CKRCQC S KF ++ Y+ T V C KCQ G QC C +GYY + P + C++CK G TN SC+ K GQC C V G++CD+C G+
Sbjct: 850 CRCYGHASSC--NPKTGVCVDCQHNTVGKNCEACAVGFYGI----ATKGTPNDCKRCQCPGGSSGNKFSESCYVDTSTTPPSVLCDKCQVGYTGRQCEECADGYYGNPLVPGGSCKPCSCNNNIDPTVSGNCDRLTGSCLQCLYNTAGFNCERCKPGYFGDAIARNCTSCVCDKKGTNPGFHYSCNHKTGQCNCLPDVEGKQCDRCAEGF 1053 HSP 3 Score: 69.3218 bits (168), Expect = 6.683e-12 Identity = 46/138 (33.33%), Postives = 63/138 (45.65%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIG 2063
C CK N G CD+CK GF +L + NP CK C CN + + G C C+ G C C + Y+ + P C C C GS + N CDK+ GQC C++G+ GR+C++ K G
Sbjct: 411 CICKRNVGGVRCDRCKAGFFNLTTD-----NPDGCKACGCNPLGTIGECNPDT---------GRC-TCKRYVEGEDCDRCASEYWGLSSTPA----GCSNCACDVGGSYD-NQCDKQTGQCRCRKGITGRQCERVKTG 528 HSP 4 Score: 59.3066 bits (142), Expect = 6.888e-9 Identity = 41/135 (30.37%), Postives = 63/135 (46.67%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKC 2054
C+C + EG CD+C EGF +L + C++C C + E ++ Q +G +C+ G +C C++ + W P C C C+ GS ++ CD+ G+C CK G IG KCD C
Sbjct: 1035 CNCLPDVEGKQCDRCAEGFWNLSSGKG-------CQQCDCCI-------EGSLRSMCNQITGQC--QCKAGFGGPRCCECEDNF---WGSPPD---GCSACNCNPAGSVHL-QCDRDTGKCLCKVGHIGDKCDMC 1146 HSP 5 Score: 55.0694 bits (131), Expect = 1.606e-7 Identity = 66/249 (26.51%), Postives = 86/249 (34.54%), Query Frame = 3
Query: 1542 SMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCD-------CKHNTEGADCDKCKEGFHDLQ--------WERASKLNPFS------------------------------CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNS---------------CDKKLGQCFCKEGVIGRKCDKCKIGY----LQTRSMLKPC 2096
SMS V Y D +V C G + +G +VCD CK N G CD+C G +R ++ F C+ C+C H+ C + GVC CQHNT G C C G+Y TK +D CK+C+C S N S CDK C+ G GR+C++C GY L KPC
Sbjct: 739 SMSSVIY---DGAVACNCDPKGTQR----DANGTLVCDPIGGQCKCKSNVIGQRCDRCAPGSFGFSNKGCSACDCDRIGAIDNFCNILTGQCQCRNWASGRQCSLCPPNMWGFPLCRPCRCYGHASSCNPKT-----------GVCVDCQHNTVGKNCEACAVGFYGIATKGTPND--CKRCQCPGGSSGNKFSESCYVDTSTTPPSVLCDK------CQVGYTGRQCEECADGYYGNPLVPGGSCKPC 961 HSP 6 Score: 53.9138 bits (128), Expect = 3.651e-7 Identity = 52/175 (29.71%), Postives = 76/175 (43.43%), Query Frame = 3
Query: 1557 YYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCD--------CKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCK 2057
YYG + L GG C+ +N GN CD C +NT G +C++CK G+ R +C C C+ + F + KTGQ + C + G QC C G++ LS C++C C GS + C++ GQC CK G G +C +C+
Sbjct: 947 YYG-NPLVPGGSCKPCSCNNNIDPTVSGN--CDRLTGSCLQCLYNTAGFNCERCKPGYFGDAIAR-------NCTSCVCDKKGTNPGFHYSCNHKTGQCN------CLPDVEGKQCDRCAEGFWN-----LSSGKGCQQCDCCIEGSLR-SMCNQITGQCQCKAGFGGPRCCECE 1099
BLAST of Netrin-1 vs. Ensembl Nematostella
Match: EDO36501 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF6]) HSP 1 Score: 169.474 bits (428), Expect = 8.985e-43 Identity = 120/421 (28.50%), Postives = 187/421 (44.42%), Query Frame = 3
Query: 813 PPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLN-----HVNISIAFKKNFEVF-YVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERA-SKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKC 2054
P F + ++ TS+CG P +Y C C+ + I+ + D + T W S ++ + N VN+SI+F K +++ ++ F S P + KS D G+ W P QYYS NC+K F + T + G + + + Q++G + + R+ N S FD Q+ Y L G D L ++ V ++ + YY VSDL V RC+C+GH+ C ++ CDC HNT G DC++C F++ W A S+ P C+RC+C+ H+ C + + Q+ G C C HNT G+ C C + +YR+ + L+H C C C G TN +C++ GQC C+ V GR+CD C
Sbjct: 36 PRFAAKMKHRAVSSTSTCGS-------PPSEYCRVKPLNGCFKCNASSPTERHPIEYIADKSPGSDATFWQSETWWDWYQKNPRDDLKVNVSISFNKTYDITGHIMFTFESPRPSKAILEKSFDKGQTWDPLQYYSFNCRKDFGMENTDPTENRFGDFSAKCTEKYSSSSPQQNGKV---------TFDFLRRYNKA--------------SFFDTQVQQYLSATDLRLRMEYPGTDGLEVAKDEV---TLKQYYYAVSDLEVIARCKCHGHARWCDFPHETGKNCDCLHNTTGDDCERCLPLFNNKTWMPATSETEPNPCERCECHSHADSCTYSQ-------QEGYGTCDDCYHNTEGHFCERCKDKFYRNMSLSLNHPEICPDCNCFPQGITNNGTCNQTTGQCECRANVTGRQCDSC 416 HSP 2 Score: 55.0694 bits (131), Expect = 1.746e-7 Identity = 48/173 (27.75%), Postives = 67/173 (38.73%), Query Frame = 3
Query: 1650 CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQ-----CNLHSQHCKFEKNVYMKT---------GQKSGGVCRKCQHN---------------------TAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIG 2063
C CK G CDKCK GF++ +S P C CN S C + V +T G +G C +C+ N T G +C C G+Y ++T C+ C CH GS + C+ + G C CK +G KC+ C+ G
Sbjct: 754 CQCKPGVTGRTCDKCKPGFYNFT---SSGCAPCDCVSTGSHHLVCNAVSGQCPCKPGVITRTCSRCNDSFYGYTTGSGCVECRCNMSGSADAQCDDVTGNCTCKNSTDGAKCAECRFGFY-NFTSA-----GCQACNCHEGGSQS-QQCNLQTGICTCKSNALGEKCESCRPG 916
BLAST of Netrin-1 vs. Ensembl Nematostella
Match: EDO36500 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF5]) HSP 1 Score: 156.762 bits (395), Expect = 7.358e-39 Identity = 131/488 (26.84%), Postives = 215/488 (44.06%), Query Frame = 3
Query: 705 SILLLGFSFYFSVAISVLYENKQTTCEFH-------GKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNS--IYSIKSLTD-----PLNQFNHTCWFSGPVY--NQHGLNH------VNISIAFKKNFEVF-YVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPP-TQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLS-RFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIV---CDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSC------DKKLGQCFCKEGVIGRKCDKCKIGY 2066
++L V V+ N Q TC F G+ C P ++ +T +++CG KY C CD + NS + + +L D P +T W S + NQ GL+ VNI+++F K +++ ++ F S+ P ++ KS+D G W Y+ C + +N+ P + P Y C + + LG E I I N + ++++TD+R+ L D M + ++++++K+YY +S++ V GRC C GH+ C G I+ C+C+HNT G DC+ C+ F++ W RA++ + C+ C CN H+ C + + + G+C+ CQHNT G+ C C +YRD +KP++H AC +G TN SC +++GQC CK V GR+CD+C G+
Sbjct: 2 AVLKATLEILCVVGSLVVCLNSQNTCRFETCYERDTGRATPCMPFTSFMSLTRNVTTSNTCGTT-------RAKYCELPGPEPCYYCDANSSNSNEQHPVTNLVDNELVLPFYAQKYTWWQSQTWWETNQLGLSSIENPPKVNITLSFGKRYQLSGHIKATFYSKRPKAMCFDKSNDFGHTWETLLCYAWRCDRFYNMEPQSNPDPANPFKLY-----CTEEYSGHEPRKLGIVEFIASKRYEICDYFNPEVQDYLSVTDVRLRLEYPASDGMELLYQ-----------------------DEQTLNKLYYAISNVEVTGRCSCNGHAMGC----SGPIMSRRCECEHNTMGTDCEMCEPLFNNRPWMRANQTHGNECQECNCNNHATSCVYNETLGY-------GLCKGCQHNTQGDHCQNCTAKHYRDLSKPINHVNAC-------LGITNNGSCLTQATDTEQIGQCSCKPNVYGRRCDQCIPGH 436 HSP 2 Score: 55.4546 bits (132), Expect = 1.327e-7 Identity = 47/147 (31.97%), Postives = 63/147 (42.86%), Query Frame = 3
Query: 1653 DCKHNTEGADCDKCKEGFHDLQWERASKLNPFS-CKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDN---GYYRDWTKP----LSHDLACKKCKCHAVGS--TNVNSCDKKLGQCFCKEG--VIGRKCDKCK 2057
+C N G C+ C EG+ + PF C C CN S+ C E GVC C+ T G +C C N G KP LS D CK C C+ G+ +N + CD+ GQC C + G+ CD+C+
Sbjct: 1075 ECHRNYTGLSCEVCAEGY----TRQPMGGTPFDRCVLCSCNDRSRFCHPET-----------GVCTDCKIGTHGYRCELCTNNVQGPECVRCKPQYWGLSKD-GCKACDCNLPGTLYSNTSVCDQTTGQCSCNATLHIGGQLCDRCE 1205 HSP 3 Score: 51.2174 bits (121), Expect = 2.112e-6 Identity = 34/77 (44.16%), Postives = 39/77 (50.65%), Query Frame = 3
Query: 1833 GGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIG 2063
GG C C+ AG +C+ C GYY LS CKKC+C GS CD G+C CK V G KCD CK G
Sbjct: 780 GGQC-PCKPGVAGLKCNHCLPGYY-----ALSSS-GCKKCECSMSGSI-TPVCDNADGKCQCKANVEGAKCDACKYG 848
BLAST of Netrin-1 vs. Ensembl Medaka
Match: NTN1 (netrin-1 [Source:NCBI gene;Acc:101155405]) HSP 1 Score: 352.058 bits (902), Expect = 7.993e-110 Identity = 216/653 (33.08%), Postives = 334/653 (51.15%), Query Frame = 3
Query: 669 FIRVLMNCFLFNSILLLGFSFYFSVAISVLYENKQTTC-EFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQ-EQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+R + L S+ + + + + C + HG C P F+N A ++ V+S+CG+ R+C CD + LTD N N TCW S + Q+ N V ++++ K FEV YV+LQFCS P+S+ IYKS DNGK W+P+Q+YS C+K +N P Q E + + D+ ++ FS+ GR + L W+T TD+++ SR H G + + S + + +Y VSDL VGGRC+C GH+++C+ + DG++VCDCKHNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD +KP+SH ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K I S T + + D ES CK K K K + +V + ++++ ++ G+ +F + I V++ Q S I + +Q+ LW+ ++V C CP I G+ YL+L ++ + ++ D ++++QWR +W RRL+KFQ + + KC+K
Sbjct: 1 MMRAVHAVLLAASLWCRSAFGGYGIGLFAAQTSPPDPCYDEHGNPRRCIPDFVNAAFGKEVKVSSTCGKTPSRYCVVTSAEKGEERTRNCHSCDASDPKKYHPPAYLTDLNNPHNLTCWQS-ENFIQYPQN-VTLTLSLGKKFEVTYVSLQFCSPRPESMVIYKSMDNGKTWVPFQFYSTQCRKMYNKPNRAVITKQNEQEAVCTDSHTDM--------YPLTGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVVFSRL-----------------HTFGDENEDDSELARDS-----YFYAVSDLQVGGRCKCNGHASRCVKDRDGSLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIK---IPVSPPTTPASSTEEASDC---ESYCKASKGKLKINMKKYCKKDYAVQVHILKADKM-GEWWKFTVNIISVYK------QGESRIRRGDQF---LWVRAKDVACKCPKIKPGKKYLLLGNDEV--SPSQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 602
BLAST of Netrin-1 vs. Ensembl Medaka
Match: ntn2 (netrin-3 [Source:NCBI gene;Acc:101160359]) HSP 1 Score: 352.443 bits (903), Expect = 1.264e-109 Identity = 211/664 (31.78%), Postives = 330/664 (49.70%), Query Frame = 3
Query: 672 IRVLMNCFLFNSILLLGFSFYFSVAISVLYENKQTTC-EFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMN------DTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHR-------------HREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+RV C L +L+ S + + + C + G C P FIN A ++ V+S CG + R C ICD + LTD + N TCW S + ++V ++++ K FE+ YV+LQFCS P+S+ IYKS D GK W+P+Q+YS C++ +N P Q E + DL + ++ FS+ GR + L W+T+TD+R+ R Q+S F G + GRD ++ S ++S +Y V D VGGRC+C GH+++C+ + +G +VCDCKHNTEG +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD +P++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + ++ ++ + + ES CKP K K + +V + V++ + V G +F + + V++ G+ + I LW+ +++ C CP I + + +L++ + R L+ D ++++QWR W RRL+KFQ K + KC K
Sbjct: 1 MRVPWRCLLGLFLLVKSVSPHSPTSPFAGQQTPLDPCYDETGTARRCIPEFINAAFGKEVMVSSVCGRPPSRSCSVVERGDERPSVRTCQICDAADPRRAHPASYLTDLNSAHNLTCWQSENLNTSP--HNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGKTWMPYQFYSSQCRRMYNKPNKATITKQNEQEALCTDGHTDL--------YPLSGGLIAFSTLDGRPSSKDFDNSPVLQDWVTVTDIRVVFGR--PQLSREFVLGAG---SNNGGRDDDPVAVTS----TLSTYFYAVGDFQVGGRCKCNGHASRCLKDKEGKLVCDCKHNTEGPECDRCKPFHYDRPWQRANAREANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGRPITHRRACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVVNPTAVVSSTE------EPADCESYCKPVKGNLKINMKKYCKKDYAVQVNVLDMETV-GDWAKFSVSLVSVYKSRGEPLKRGDNI--------LWVHMKDLACKCPKIQMSKKFLVMGGSEGGTGPAAGPGVGATSPGAERVGLVADKNSLVIQWRDVWSRRLRKFQRKEKKGKCSK 629
BLAST of Netrin-1 vs. Ensembl Medaka
Match: ntn2 (netrin-3 [Source:NCBI gene;Acc:101160359]) HSP 1 Score: 352.443 bits (903), Expect = 1.264e-109 Identity = 211/664 (31.78%), Postives = 330/664 (49.70%), Query Frame = 3
Query: 672 IRVLMNCFLFNSILLLGFSFYFSVAISVLYENKQTTC-EFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMN------DTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHR-------------HREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+RV C L +L+ S + + + C + G C P FIN A ++ V+S CG + R C ICD + LTD + N TCW S + ++V ++++ K FE+ YV+LQFCS P+S+ IYKS D GK W+P+Q+YS C++ +N P Q E + DL + ++ FS+ GR + L W+T+TD+R+ R Q+S F G + GRD ++ S ++S +Y V D VGGRC+C GH+++C+ + +G +VCDCKHNTEG +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD +P++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + ++ ++ + + ES CKP K K + +V + V++ + V G +F + + V++ G+ + I LW+ +++ C CP I + + +L++ + R L+ D ++++QWR W RRL+KFQ K + KC K
Sbjct: 1 MRVPWRCLLGLFLLVKSVSPHSPTSPFAGQQTPLDPCYDETGTARRCIPEFINAAFGKEVMVSSVCGRPPSRSCSVVERGDERPSVRTCQICDAADPRRAHPASYLTDLNSAHNLTCWQSENLNTSP--HNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGKTWMPYQFYSSQCRRMYNKPNKATITKQNEQEALCTDGHTDL--------YPLSGGLIAFSTLDGRPSSKDFDNSPVLQDWVTVTDIRVVFGR--PQLSREFVLGAG---SNNGGRDDDPVAVTS----TLSTYFYAVGDFQVGGRCKCNGHASRCLKDKEGKLVCDCKHNTEGPECDRCKPFHYDRPWQRANAREANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGRPITHRRACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVVNPTAVVSSTE------EPADCESYCKPVKGNLKINMKKYCKKDYAVQVNVLDMETV-GDWAKFSVSLVSVYKSRGEPLKRGDNI--------LWVHMKDLACKCPKIQMSKKFLVMGGSEGGTGPAAGPGVGATSPGAERVGLVADKNSLVIQWRDVWSRRLRKFQRKEKKGKCSK 629
BLAST of Netrin-1 vs. Ensembl Medaka
Match: ntn2 (netrin-3 [Source:NCBI gene;Acc:101160359]) HSP 1 Score: 352.443 bits (903), Expect = 1.264e-109 Identity = 211/664 (31.78%), Postives = 330/664 (49.70%), Query Frame = 3
Query: 672 IRVLMNCFLFNSILLLGFSFYFSVAISVLYENKQTTC-EFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMN------DTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHR-------------HREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+RV C L +L+ S + + + C + G C P FIN A ++ V+S CG + R C ICD + LTD + N TCW S + ++V ++++ K FE+ YV+LQFCS P+S+ IYKS D GK W+P+Q+YS C++ +N P Q E + DL + ++ FS+ GR + L W+T+TD+R+ R Q+S F G + GRD ++ S ++S +Y V D VGGRC+C GH+++C+ + +G +VCDCKHNTEG +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD +P++H ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K + ++ ++ + + ES CKP K K + +V + V++ + V G +F + + V++ G+ + I LW+ +++ C CP I + + +L++ + R L+ D ++++QWR W RRL+KFQ K + KC K
Sbjct: 1 MRVPWRCLLGLFLLVKSVSPHSPTSPFAGQQTPLDPCYDETGTARRCIPEFINAAFGKEVMVSSVCGRPPSRSCSVVERGDERPSVRTCQICDAADPRRAHPASYLTDLNSAHNLTCWQSENLNTSP--HNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGKTWMPYQFYSSQCRRMYNKPNKATITKQNEQEALCTDGHTDL--------YPLSGGLIAFSTLDGRPSSKDFDNSPVLQDWVTVTDIRVVFGR--PQLSREFVLGAG---SNNGGRDDDPVAVTS----TLSTYFYAVGDFQVGGRCKCNGHASRCLKDKEGKLVCDCKHNTEGPECDRCKPFHYDRPWQRANAREANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGRPITHRRACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVVNPTAVVSSTE------EPADCESYCKPVKGNLKINMKKYCKKDYAVQVNVLDMETV-GDWAKFSVSLVSVYKSRGEPLKRGDNI--------LWVHMKDLACKCPKIQMSKKFLVMGGSEGGTGPAAGPGVGATSPGAERVGLVADKNSLVIQWRDVWSRRLRKFQRKEKKGKCSK 629
BLAST of Netrin-1 vs. Ensembl Medaka
Match: NTN1 (netrin-1 [Source:NCBI gene;Acc:101155405]) HSP 1 Score: 344.739 bits (883), Expect = 2.364e-107 Identity = 214/653 (32.77%), Postives = 331/653 (50.69%), Query Frame = 3
Query: 669 FIRVLMNCFLFNSILLLGFSFYFSVAISVLYENKQTTC-EFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM------NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQ-EQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEK 2603
+R + L S+ + + + + C + HG C P F+N A ++ V+S+CG+ CD + LTD N N TCW S + Q+ N V ++++ K FEV YV+LQFCS P+S+ IYKS DNGK W+P+Q+YS C+K +N P Q E + + D+ ++ FS+ GR + L W+T TD+++ SR H G + + S + + +Y VSDL VGGRC+C GH+++C+ + DG++VCDCKHNT G +CD+CK +D W+RA+ C C CNLH++ C+F +Y +G+KSGGVC C+HNTAG CH+C G+YRD +KP+SH ACK C CH VG+ +C++ GQC CK+GV G C++C GY Q+RS + PC+K I S T + + D ES CK K K K + +V + ++++ ++ G+ +F + I V++ Q S I + +Q+ LW+ ++V C CP I G+ YL+L ++ + ++ D ++++QWR +W RRL+KFQ + + KC+K
Sbjct: 1 MMRAVHAVLLAASLWCRSAFGGYGIGLFAAQTSPPDPCYDEHGNPRRCIPDFVNAAFGKEVKVSSTCGKT----------------------CDASDPKKYHPPAYLTDLNNPHNLTCWQS-ENFIQYPQN-VTLTLSLGKKFEVTYVSLQFCSPRPESMVIYKSMDNGKTWVPFQFYSTQCRKMYNKPNRAVITKQNEQEAVCTDSHTDM--------YPLTGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVVFSRL-----------------HTFGDENEDDSELARDS-----YFYAVSDLQVGGRCKCNGHASRCVKDRDGSLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKACDCHPVGAAG-KTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIK---IPVSPPTTPASSTEEASD---CESYCKASKGKLKINMKKYCKKDYAVQVHILKADKM-GEWWKFTVNIISVYK------QGESRIRRGDQF---LWVRAKDVACKCPKIKPGKKYLLLGNDEV--SPSQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 580
BLAST of Netrin-1 vs. Planmine SMEST
Match: SMESG000076695.1 (SMESG000076695.1) HSP 1 Score: 1375.15 bits (3558), Expect = 0.000e+0 Identity = 676/676 (100.00%), Postives = 676/676 (100.00%), Query Frame = 3
Query: 684 MNCFLFNSILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFLQKKSKIKHNRINRVGKNKRSFLLTKNPFSPEFIS 2711
MNCFLFNSILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEKRKRIRFKKFCRRDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFLQKKSKIKHNRINRVGKNKRSFLLTKNPFSPEFIS
Sbjct: 1 MNCFLFNSILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEKRKRIRFKKFCRRDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFLQKKSKIKHNRINRVGKNKRSFLLTKNPFSPEFIS 676
BLAST of Netrin-1 vs. Planmine SMEST
Match: SMESG000050895.1 (SMESG000050895.1) HSP 1 Score: 544.658 bits (1402), Expect = 0.000e+0 Identity = 284/660 (43.03%), Postives = 402/660 (60.91%), Query Frame = 3
Query: 663 FIFIRVLMNCFLFNSILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRD-CSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRK----MNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFLQKKSKI 2627
IFIR +I +L S + ++ V++E++ + C +G+ C P F NI + K TS+CG P+ IC +W ++ R CSICD K+ Y +TD N TCWFSGP+ G N VNI+++ KK+FEV+Y+ALQ C LPDSI IYKS D G W PWQ++S++C +AF +P T E Q C +L ++ + GQAE++LPFS+ GR + L++W+T+TDLRI+L RF + S+ + + + + N+ VN K+ V++G+SDL+VGGRC+C GH+N+C+I+++ I CDC HNTEG +C++CK + D W+RA++ N CK C CNLHS C F +Y++ +GGVC C+H+T GN C C+NG++R+WTKP H AC CKCH +GS N CDKK GQC+C++GV G+ CD+CK GY Q+ S ++PC+ + S DM NT CK C+EKRKRI FKKFCRR SVF SKE+HG M+R+EL+I E+WRV + +F+ + + WI+ E+VRC+CP + LG+SYLIL + K Y + +EL +DSR+VML W SWERRLQKFQ + KCE++ +KK KI
Sbjct: 1 MIFIR---------TIAILNLSVWIH-SVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICD--AKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNL----VNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPS---------------SGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYFKKKMKI 629
BLAST of Netrin-1 vs. Planmine SMEST
Match: SMESG000050895.1 (SMESG000050895.1) HSP 1 Score: 532.717 bits (1371), Expect = 3.393e-178 Identity = 283/660 (42.88%), Postives = 400/660 (60.61%), Query Frame = 3
Query: 663 FIFIRVLMNCFLFNSILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRD-CSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRK----MNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFLQKKSKI 2627
IFIR +I +L S + ++ V++E++ + C +G+ C P F NI + K TS+CG P+ IC +W ++ R CSICD K+ Y +TD N TCWFSGP+ G N VNI+++ KK+FEV+Y+ALQ C LPDSI IYKS D G W PWQ++S++C +AF +P T E Q C +L ++ + GQAE++LPFS+ GR + L++W+T+TDLRI+L RF + S+ + + + + N+ VN K+ V++G+SDL+VGGRC+C GH+N+C+I+++ I CDC HNTEG +C++CK + D W+RA++ N CK CQC HS C F +Y +T + GGVC +C+HNT G+ C C +YRD TKP++H AC CKCH +GS N CDKK GQC+C++GV G+ CD+CK GY Q+ S ++PC+ + S DM NT CK C+EKRKRI FKKFCRR SVF SKE+HG M+R+EL+I E+WRV + +F+ + + WI+ E+VRC+CP + LG+SYLIL + K Y + +EL +DSR+VML W SWERRLQKFQ + KCE++ +KK KI
Sbjct: 1 MIFIR---------TIAILNLSVWIH-SVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICD--AKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNL----VNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPS---------------SGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYFKKKMKI 629
BLAST of Netrin-1 vs. Planmine SMEST
Match: SMESG000069610.1 (SMESG000069610.1) HSP 1 Score: 391.734 bits (1005), Expect = 4.350e-125 Identity = 233/638 (36.52%), Postives = 347/638 (54.39%), Query Frame = 3
Query: 774 TTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFC-SELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPT-------QEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKM----NDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGN-IVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQ-----FISEISQ--------EQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDS-RTVMLQWRPSWERRLQKFQTKANEEKCEKF 2606
+ C HG Y C PPF NI + + + C + ++CP + R N I TD N TCW S P+ NHVNI+ +F K FEV+Y++L C S +P++I YKS++ G W PW Y + NC FN+ T +F IQ + + CF L D E ++ F++ + + +LI W++ +D+RITL +FD+ K ++ N+ F+ N K +SD+S+GGRC+C GH+N C N N I C C+HNTEG DC+KCK+ + DL W RA+ +P CK+C+CNLHS +C F +++Y+ Q +GGVC CQHNTAG +CH+C++GYYRDWTKPL H CKKC CH +G+ + CDK+ GQC CK GV G C++C G+ Q+ S PCV KY+ M + E++CK CD KR RIRF+KFCR+D+VF ++S+E+ G +RF++ + +W I FI I + + P+W+ +++C+C + LG++YL ++K YH+++R ELL+ S R+++L W P+W+RRL +F+ K + +C KF
Sbjct: 7 SPCYAHGSAYQCMPPFTNIVENMIPKIETLCKK---KEVCP---------------IKSPRDNLI------TDYHLTHNQTCWKSVPL----QANHVNITFSFAKRFEVYYISLTPCESGIPNAIAFYKSNNFGITWKPWHYLATNCLSMFNMKETTIPSLQFNDFRIQRREQ---AARCFPLKLSLTDN-----EPVVAFNTVLEGAYENVGDSSLIDWMSASDIRITLFKFDNP-------------KPKKS----NIFRFARNS---PKKILSISDISIGGRCKCNGHANACNKNPITNKIECVCQHNTEGQDCEKCKKNYLDLPWARATVNSPAQCKKCECNLHSSNCYFSQDLYILRKQITGGVCTNCQHNTAGVRCHYCNDGYYRDWTKPLDHKFVCKKCTCHIIGAKFPDRCDKRTGQCLCKSGVTGEMCNRCASGFRQSNSTETPCV------------------KYIQMESAENKCKACDSKRTRIRFRKFCRKDAVFSVTLQSQEIIGDFIRFDVTVDNIWHSKNSIKDLYPGIFIESIMRPSSKSRLNNRPTNPIWLKLRDLKCNCVQLQLGQTYLFIIKSTTYHYQNRAELLIKSPRSIILIWNPTWKRRLNRFKQKKEKGECSKF 570
BLAST of Netrin-1 vs. Planmine SMEST
Match: SMESG000006806.1 (SMESG000006806.1) HSP 1 Score: 382.104 bits (980), Expect = 1.663e-120 Identity = 240/658 (36.47%), Postives = 370/658 (56.23%), Query Frame = 3
Query: 756 LYENKQTTCEFHGKDYYCTPPFINIAQRA-KITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSEL-PDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPT--QEFPIQEGLEYSL--SPTCFDLNQKQKDGNLGQAESILPFSST---IGRKMNDTLIKWITITDLRITLSRFDDQ-MSSYFD-------YGKYFLLKHRRGR--DIL----NMSTFSVNDKSMSKV--YYGVSDLSVGGRCQCYGHSNKCIINN-DGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEXXXXXXXXXXXXXDSVFMGVIESKEVHGKMVRFELQIKEVWRV-SGKISQF-------ISEISQEQY---AVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFLQKK 2618
L+ + C GK + C PPF NI + +TS+CG+ IC +H +C C D +SI LTD N T W S V HG N VNI+ +F K FE++Y++L L PDSI I KS DNG W W Y+SK+C ++F + P + + E ++ S TC + K GNL + S+L F++ +D W++ T++RITL + + ++S+ D +YF +R+ IL + N S+ K+ ++ ++D+S+GGRCQCYGH+ +C+ N D CDC+HNT G DC+ C+EGF D +W A+ + CKRC CNLHS+ C+F + +Y+ + ++SGGVC C+HNT G CH C+ GY+RDW+KPLSH C KC+CH +GS + CD++ QC CK GV G C++C+ G+ QT+S + PCV D+ + + E+ C+ C+ KRKRIRFKK+CR+D+V + ++S+E HG+M RFE+++ V+R+ + K ++ ++ I Q+ P+WI +++C CP++ LG +YL+++K + R ELLLD ++V L W+ +WERR++KF K ++ CEK+ K+
Sbjct: 27 LHGGSNSLCYSEGKAFRCVPPFTNIIENMIPDEITSTCGQNKKQRIC-------VDHI-NCHSCMKD----THSINYLTDQHLNNNITFWASDFV--NHGDN-VNITFSFGKLFEIYYISLVLIPLLEPDSIIISKSIDNGTSWTEWHYFSKDCYRSFGIQPMDFNHYSDSKITESTVDQSLTCTSI-PDSKLGNLVNSPSVLAFTTNNPNFFSHASDQYNSWMSATNIRITLRKSETNFLNSHLDGFTYPPHLKQYFNRIYRKNNYSSILPVNRKLKQKKRNSPSVLKISDFFALADISIGGRCQCYGHAGRCLKNPVDNTYHCDCQHNTAGKDCEMCREGFVDKRWSVATVNSAAECKRCNCNLHSKKCEFNEKLYIVSNKQSGGVCVGCEHNTDGRYCHQCNKGYHRDWSKPLSHHHVCIKCRCHPIGSIYPDVCDQRNSQCTCKTGVGGLSCNRCQKGFQQTKSPITPCVDVIDLHKIPMAQAP------------ENRCQHCNNKRKRIRFKKYCRKDAVLLVTMQSREQHGEMARFEMKVNYVYRIDTSKFTEMHPDFLASMNGIMSNQFIHSTFPMWIKETDLKCKCPSLQLGMTYLVILKLHAIKYLERSELLLDQKSVALPWQKTWERRMKKFSNKEHQGLCEKWKLKR 656 The following BLAST results are available for this feature:
BLAST of Netrin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Netrin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Netrin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Netrin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Netrin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30023928 ID=SMED30023928|Name=Netrin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2794bpback to top protein sequence of SMED30023928-orf-1 >SMED30023928-orf-1 ID=SMED30023928-orf-1|Name=SMED30023928-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=677bp MNCFLFNSILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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