Symplekin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30023927 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Symplekin vs. Ensembl Human
Match: SYMPK (symplekin [Source:HGNC Symbol;Acc:HGNC:22935]) HSP 1 Score: 639.802 bits (1649), Expect = 0.000e+0 Identity = 397/1112 (35.70%), Postives = 628/1112 (56.47%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSS-KRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSL--ESKEKRETFQDES--NSNSILEDFPMSGYANQ----KSKNQMTLLKKH-PFSTQKPFNLESVT--KTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
+RVVDL N + + K + Q++ELI+ K+P+LLDNF ++I+ +++ VR VI FIE ACK D +L+ K + L L+ DE+ NV+K+ M +Y ++L +K + S E + C +V A+ + DS N G+ IK +E +++ S R DSEIP+ +E+D+SLD+IP D P +Q +L + G L+K + SS ++ T L SL NIA+QRP FMS VI+++E H N+P L + QV+S+RK LK LLS+LKHP+ LEF +Q+TTLL+DLG Q+EI R +P + + RKR +++ S+ K+ + N D D PS K+ + ++ E L L T NV +LVL+SM+ LPE MP +FQ+ YTP+ +AGT+ QI HL+RL++ Q+ +AG ++K+ +E ++E + S+L +S S + M+ L++ P + ++P + VT + ++IF S ++ PL + +++ + + + R IL SL + G L E++ + ++DV+ R D+ + L +EY +Y A + ++ Y+ L+ +L L D K+ F +++LEAPLIT AL ++R YC + G +R+L RP + + L ++LD SS + +VRS AL K + E E + FA L L+ P + + T + WT+E V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +H LTDK PSP +V++++++YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P ELL+A+H ++ ++K +I+A+ +CF E+ ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+LSRLI KQVWK +W+GFI+CC + QSF V+LQLP +L +VF+ PE R + ++ + T Q+ H N+I++++ +
Sbjct: 34 ERVVDLLNQAA-LITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVIS----ELQEACWDMVSAMAGDIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEIPRRQEHDISLDRIPRDH--PYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDT----RKRPRDDSDSTLKKMKLEPNLGEDDEDKDLE-------PGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKTESVLIKRRLSAQGQAISVVGSLSSMSPLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSD---VLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQV-RIKILASLVTQFNSG--LKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGAS-------------GSLDKYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVVRKYCEDESRTYLGMSTLRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKR-MYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEGNSALSPLNPGELLIALHNIDSVKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMTILEASG 1102
BLAST of Symplekin vs. Ensembl Human
Match: SYMPK (symplekin [Source:HGNC Symbol;Acc:HGNC:22935]) HSP 1 Score: 500.745 bits (1288), Expect = 2.704e-157 Identity = 337/978 (34.46%), Postives = 533/978 (54.50%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSS-KRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSL--ESKEKRETFQDES--NSNSILEDFPMSGYANQ----KSKNQMTLLKKH-PFSTQKPFNLESVT--KTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKM 2958
+RVVDL N + + K + Q++ELI+ K+P+LLDNF ++I+ +++ VR VI FIE ACK D +L+ K + L L+ DE+ NV+K+ M +Y ++L +K + S E + C +V A+ + DS N G+ IK +E +++ S R DSEIP+ +E+D+SLD+IP D P +Q +L + G L+K + SS ++ T L SL NIA+QRP FMS VI+++E H N+P L + QV+S+RK LK LLS+LKHP+ LEF +Q+TTLL+DLG Q+EI R +P + + RKR +++ S+ K+ + N D D PS K+ + ++ E L L T NV +LVL+SM+ LPE MP +FQ+ YTP+ +AGT+ QI HL+RL++ Q+ +AG ++K+ +E ++E + S+L +S S + M+ L++ P + ++P + VT + ++IF S ++ PL + +++ + + + R IL SL + G L E++ + ++DV+ R D+ + L +EY +Y A + ++ Y+ L+ +L L D K+ F +++LEAPLIT AL ++R YC + G +R+L RP + + L ++LD SS + +VRS AL K + E E + FA L L+ P + + T + WT+E V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +H LTDK PSP +V++++++YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P ELL+A+H ++ ++K +I+ +
Sbjct: 34 ERVVDLLNQAA-LITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVIS----ELQEACWDMVSAMAGDIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEIPRRQEHDISLDRIPRDH--PYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDT----RKRPRDDSDSTLKKMKLEPNLGEDDEDKDLE-------PGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKTESVLIKRRLSAQGQAISVVGSLSSMSPLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSD---VLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQV-RIKILASLVTQFNSG--LKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGAS-------------GSLDKYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVVRKYCEDESRTYLGMSTLRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKR-MYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEGNSALSPLNPGELLIALHNIDSVKCDMKSIIKGEAL 968
BLAST of Symplekin vs. Ensembl Human
Match: SYMPK (symplekin [Source:HGNC Symbol;Acc:HGNC:22935]) HSP 1 Score: 500.745 bits (1288), Expect = 2.704e-157 Identity = 337/978 (34.46%), Postives = 533/978 (54.50%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSS-KRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSL--ESKEKRETFQDES--NSNSILEDFPMSGYANQ----KSKNQMTLLKKH-PFSTQKPFNLESVT--KTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKM 2958
+RVVDL N + + K + Q++ELI+ K+P+LLDNF ++I+ +++ VR VI FIE ACK D +L+ K + L L+ DE+ NV+K+ M +Y ++L +K + S E + C +V A+ + DS N G+ IK +E +++ S R DSEIP+ +E+D+SLD+IP D P +Q +L + G L+K + SS ++ T L SL NIA+QRP FMS VI+++E H N+P L + QV+S+RK LK LLS+LKHP+ LEF +Q+TTLL+DLG Q+EI R +P + + RKR +++ S+ K+ + N D D PS K+ + ++ E L L T NV +LVL+SM+ LPE MP +FQ+ YTP+ +AGT+ QI HL+RL++ Q+ +AG ++K+ +E ++E + S+L +S S + M+ L++ P + ++P + VT + ++IF S ++ PL + +++ + + + R IL SL + G L E++ + ++DV+ R D+ + L +EY +Y A + ++ Y+ L+ +L L D K+ F +++LEAPLIT AL ++R YC + G +R+L RP + + L ++LD SS + +VRS AL K + E E + FA L L+ P + + T + WT+E V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +H LTDK PSP +V++++++YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P ELL+A+H ++ ++K +I+ +
Sbjct: 34 ERVVDLLNQAA-LITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVIS----ELQEACWDMVSAMAGDIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEIPRRQEHDISLDRIPRDH--PYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDT----RKRPRDDSDSTLKKMKLEPNLGEDDEDKDLE-------PGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKTESVLIKRRLSAQGQAISVVGSLSSMSPLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSD---VLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQV-RIKILASLVTQFNSG--LKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGAS-------------GSLDKYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVVRKYCEDESRTYLGMSTLRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKR-MYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEGNSALSPLNPGELLIALHNIDSVKCDMKSIIKGEAL 968
BLAST of Symplekin vs. Ensembl Human
Match: SYMPK (symplekin [Source:HGNC Symbol;Acc:HGNC:22935]) HSP 1 Score: 278.485 bits (711), Expect = 8.362e-80 Identity = 211/641 (32.92%), Postives = 332/641 (51.79%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSS-KRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSL--ESKEKRETFQDES--NSNSILEDFPMSGYANQ----KSKNQMTLLKKH-PFSTQKP--------------------FNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKA 1896
+RVVDL N + + K + Q++ELI+ K+P+LLDNF ++I+ +++ VR VI FIE ACK D +L+ K + L L+ DE+ NV+K+ M +Y ++L +K + S E + C +V A+ + DS N G+ IK +E +++ S R DSEIP+ +E+D+SLD+IP D P +Q +L + G L+K + SS ++ T L SL NIA+QRP FMS VI+++E H N+P L + QV+S+RK LK LLS+LKHP+ LEF +Q+TTLL+DLG Q+EI R +P + + RKR +++ S+ K+ + N D D PS K+ + ++ E L L T NV +LVL+SM+ LPE MP +FQ+ YTP+ +AGT+ QI HL+RL++ Q+ +AG ++K+ +E ++E + S+L +S S + M+ L++ P + ++P F L V K L ++ + + KRIL RA + + R IL SL + G L E++ + ++DV+ R D+ + L +EY +Y A
Sbjct: 34 ERVVDLLNQA-ALITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVIS----ELQEACWDMVSAMAGDIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEIPRRQEHDISLDRIPRDH--PYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDT----RKRPRDDSDSTLKKMKLEPNLGEDDEDKDLE-------PGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKTESVLIKRRLSAQGQAISVVGSLSSMSPLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLKPLTDAQVEAMKLGAVKRIL------------RAEKAVACSGAAQV----------RIKILASLVTQFNSG--LKAEVLSFILEDVRARLDLAFAWLYQEYNAYLA 632
BLAST of Symplekin vs. Ensembl Human
Match: SYMPK (symplekin [Source:HGNC Symbol;Acc:HGNC:22935]) HSP 1 Score: 83.1889 bits (204), Expect = 1.605e-18 Identity = 37/77 (48.05%), Postives = 53/77 (68.83%), Query Frame = 1
Query: 3082 PRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQ 3312
PR+ G+V+N+LSRLI KQVWK +W+GFI+CC + QSF V+LQLP +L +VF+ PE R + ++ + T Q
Sbjct: 2 PRLGGFVMNILSRLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQ 78
BLAST of Symplekin vs. Ensembl Celegans
Match: symk-1 (SYMpleKin cleavage and polyadenylation factor [Source:UniProtKB/TrEMBL;Acc:O16929]) HSP 1 Score: 236.498 bits (602), Expect = 2.497e-63 Identity = 265/1081 (24.51%), Postives = 506/1081 (46.81%), Query Frame = 1
Query: 181 SLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRF-LIEDESF----NVMKRLATAMMTIYPLSLSQAIKLKSSSADDI-EAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQR----FPDSEIPKGKE-----NDLSLDKIPAD---LTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQF---MSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLID-LGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLN--TVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQL----VSAGYLSLESKEKRETFQDESNSNSILEDFPMSGYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAEL-YRELV-------------------KYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLAT----ISDYDAVLVGVLKELITSDV-KETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVD-WTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLND--KLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFAN-VELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLW-DGFIRCCVKLGQQSF-AVLLQLPVDKLESV 3246
S+LDNF ++L ++ + ++DF+ A D L NK+VER F LI ++S +V+KR+ A +YP+ L AI K+ +A+ +AF ++ + V + G+ + +K +E +++ QS + S I +E N +SL +P L+ Q+E E F+ L+K ++S ++ T++ SL I + RPQ+ + RV + + H N+P L + QV +RK+ K +LL LK P+ + ++TT+L + LG + E+ +++P + + ++ R ++ R + + + +D A PS + + ++ +K ++ LN TV+N LV +S+ LP MP AF S+YTPIA AGT+ LS L++ Q+ + GY L+ + K+E A K++++ + Q P + +++ +P + I +S + I +P++ K +A F D + + ++L + + GGA L Y++LV ++ + D K R D+ L L + Y Y+ Y +E A T + YD + +L ++ ++ KE F ++LLE PL+T A+ L+ C AK N ++G ++REL R R +LL + + E+RS+ L K + + D A+ ++ LQ P P+ + D WTDE+ + L ++ LMP + L+ LA V+ ++ + KR +++ ++ +++ + E ++ L+E+C L+ R++ +LT++ PS +++KLK ++ + D+R ++PI+ GL + E++ ++P + + K V+ +FR+L V DP G+ V P E++ H++E N E ++++ + F + + + S I + +P LF+ +L F + +V N+ ++ +K++++ S W F +C +L +++ AV+ L ++ E +
Sbjct: 53 SILDNFLTEMLEFAELNDSRILCLLVDFLLKASAKDFTLCNKTVERYSFYLIPNKSIKRYESVIKRVVVASTNLYPIVLEFAIMDKNDNAESCWDAFN---LLKNRICMLVSDDHEGVRTVTVKFLEALILCQSPKPRELATGSNISWAREANTRFNRISLSDVPRSHRFLSYHKTQLEAEEN-----FSALLKQTTVAEATSQNLITVIESLCMITRCRPQWENALPRVFDVIKALHSNVPPMLSKGQVKFLRKSFKYNLLRFLKLPASVPLQQKITTMLTNYLGASPREVQQSIP-PELIQKIAPPRPPQHPAEPVAKRPKIQ-----NQIFEDDDDDDDEAGPSTSTVNAKDARTEAIDMTAKFIMECLNHETVMN---LVKISLYTLPSEMPAAFASSYTPIANAGTEPNRQELSELMAVQMTNKEIGPGYEWLQQQRKKEY------------------EARNKARSEGMAI------AQTPIHEPNMSNRVPAQ----IVKQSLQEINTLPVIQ---KAKKAFNLVEEAVVFDDKEAAEMFELAYESVLQAERRVVAGGARLMYQKLVVRLTTRFWEDCTPFEEKLIEFVLADHKKRNDLALLWLCELYAQYQGYSNCALFMKEMIAGQEGLTQAQRLDRYDQAMCKMLDAMLERNMEKEALFYKVLLETPLLTPNAIERLKQVCLAKEN-EHGMAMLRELIMTRNRQRPQLLQFLFGLFFMERPELRSSCLEVVKELCYLP-FIRSSLSDQARMQIHDCLQESP-----PMYMRSSEDSDQWTDEMYKNSLAVYSTLMPSDPLLLIPLASVYAQSTNVFKRVVLRSLEPVFRQL--SQEMVISLIEDCPYGAETLVARLVVLLTERITPSTDLIQKLKILHDERKMDIRALLPIIGGLEREEVVRLIPTFIFRAEYQKSVNVLFRKLYTVR--DPQTGNLVFD-----PIEVIKEYHKIEPKNDNEAELLVNNLEFLF-DPALLKPDTASQAIEAVFKWENVPFLFLHSLYTLFHKFKTFESFVANLFYKVTEKKMYQQSDRWKQAFFKCIKELKTKAYPAVITFLSFEEYEEL 1068
BLAST of Symplekin vs. Ensembl Fly
Match: Sym (gene:FBgn0037371 transcript:FBtr0078723) HSP 1 Score: 424.861 bits (1091), Expect = 2.164e-128 Identity = 320/1136 (28.17%), Postives = 562/1136 (49.47%), Query Frame = 1
Query: 79 RVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLS---SKRARTSVNAHSDYS---DLTYNDSIIKKFAAPSLEQK--SPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLV------SAGYLSLESKEKRETFQ-----------DESNSNSILED-FPMSGYANQK-------SKNQMTLLKKHPFSTQKPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITSDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSI--HPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSL-IHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPL--MVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSN---AILSLINSDSV 3363
+VVD CN + K + +++E ++ L + F E +L L + N VR V+ F+E CKV +L+ + + L+ D S V+KR+ A +IY L L +A+ +I ++ +D+ N G+ IK +E +V+LQS F D + K ++ D SL +P T+ + E L++ G + ++L++ H SS ++ +SL IAK RP FM V+E+F+ + N+P L + QV+S+RK+LK L +LLK+ EF S + +L+DLG + +EI + +PK D+ +R+++ N + +KRAR + +L + +K + + +K + R P V L E LP L P +P F YTPI Q Q+ ++SR QL A S E + + Q DE + E+ F A +K +K + T+++K K L+ +TK LP ++ ++ +RIL N ++C + S+ L ++ +A F Y ++++ ++D+K R D+ S L +EY+ + + EN P A + ++ G+ + D K R+ LEAP++ ++ L + +G ++I++L RP + + ++L+FS + +++R A + + + I +FA L ++ Q P ++ T P DW ++ + C L L+P + + + +VFV +KRTI++ +DIPIK+MG+ S +L+L+E+C L+IR+I+ILT++ +PSP +V +++++Y NK DVR++IP+L GLT++E+I +LPKL+ LN +V EVF RLL + A +F +T + P ++LVA+H ++ + ++K +++A+ +C E+ ++TQE L V+ QL+++ LPTL MRT +QS ++YPR+ +V+N+L RLI KQVW+ +W+GF++ +L QS +LL LP +L P+ R + Y ++ Q + ++ S +L +I+ SV
Sbjct: 29 KVVDWCNELV-IASPSTKCELLAKVQETVLGSCAELAEEFLESVLSLAHDSNMEVRKQVVAFVEQVCKVKVELLPHVINVVSMLLRDNSAQVIKRVIQACGSIYKNGLQYLCSLMEPGDSAEQAWNILSLIKAQILDMIDNENDGIRTNAIKFLEGVVVLQS--FADEDSLK-RDGDFSLADVPDHCTL--FRREKLQEEGNNILDILLQFHGTTHISSVNLIACTSSLCTIAKMRPIFMGAVVEAFKQLNANLPPTLTDSQVSSVRKSLKMQLQTLLKNRGAFEFASTIRGMLVDLGSSTNEIQKLIPKMDKQEMARRQKRILENAAQSLAKRARLACEQQDQQQREMELDTEELERQKQKSTRVNEKFLAEHFRNPETVVTLVLEFLPSL-----------------PTEVPQKFLQEYTPIREMSIQQQVTNISRFFGEQLSEKRLGPGAATFSREPPMRVKKVQAIESTLTAMEVDEDAVQKLSEEEFQRKEEATKKLRETMERAKGEQTVIEKMK-ERAKTLKLQEITKPLPRNLKEKFLTDAVRRIL------NSERQC-----------------IKGGVSSKRRKLVTVIAATFPDNVRYG-IMEFILEDIKQRIDLAFSWLFEEYSLLQGFTRHTYVKTENR--PDHAYNELLNKLIFGIGERCDHKD-KIILIRRVYLEAPILPEVSIGHLVQLSLDDEFSQHGLELIKDLAVLRPPRKNRFVRVLLNFSVHERLDLRDLAQAHLVSLYHVHKILPARIDEFALEWLKFIEQESPPAAVFSQDFGRPTEEP-DWREDTTKVCFGLAFTLLPYKPEVYLQQICQVFVSTSAELKRTILRSLDIPIKKMGVESPTLLQLIEDCPKGMETLVIRIIYILTER-VPSPHEELVRRVRDLYQNKVKDVRVMIPVLSGLTRSELISVLPKLIKLNPAVVKEVFNRLLGIGA------EFAHQTMAMTPTDILVALHTIDTSVCDIKAIVKATSLCLAERDLYTQEVLMAVLQQLVEVTPLPTLMMRTTIQSLTLYPRLANFVMNLLQRLIIKQVWRQKVIWEGFLKTVQRLKPQSMPILLHLPPAQLVDALQQCPDLRPALSEYAES-MQDEPMNGSGITQQVLDIISGKSV 1104
BLAST of Symplekin vs. Ensembl Zebrafish
Match: sympk (symplekin [Source:ZFIN;Acc:ZDB-GENE-060526-361]) HSP 1 Score: 610.527 bits (1573), Expect = 0.000e+0 Identity = 380/1108 (34.30%), Postives = 621/1108 (56.05%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGY-------LSLESKEKRETFQDESNSNS--ILEDFPMSGYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLPTETMQEIFHESFKRI-----LVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELIT-SDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINS 3354
+RVVDL N + EEK + + Q++EL++ K+PSLLDNF ++I+ +++ VR VI FIE ACK D++L+ + + L L+ DES NV+K+ + +Y ++L ++ KS + + + +++ +DS N G+ IK E ++I S R PDS+ PK +E D+SLDKIP D T ++ + L + G + L+K + SS ++ T L SL +A+QRP FMS V++++E+ H N+P L + QV+S+RK LK L+++LKHPS ++FH Q++TLL DLGM+ SEI R P A Q +++ E + KR + + A D D K+ AP + K S L+ E L L T NV +LVL+SM+ LPE MP +FQ+ YTP+ +AGT QI HL+RL++ Q+ +AG + + + K E ES+S I+ S + K P + P + LP+ ++ K++ +V P ++++ AN + + R +L L + G + +L+++ ++D+++R ++ SLL EY Y +S+ + Y+ L +L L + ++ F +++LEAP+IT AL +++ YC + G ++EL RP + + L ++L+ +S + +VRS ALS K + E+ + I FA T + +L+ P + + T + WT+E VR CLYL+L+L+P+NH L+H LA V+ +A +KR+++++I+ PI+ MGMNS ++L LVENC L+ R +HILTDK PSP +VE+++++YH + DVR +IP++ GL K E+I+ LPKL+ LN +V EVF RLL + SP+ P ELL+A+H ++ + ++K +I+A+ +CF EK ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+L+RLI KQVWK +W+GF++CC + QS+ VLLQLP +L SVF PE R + +++ + T Q+ H +I++++ +
Sbjct: 29 ERVVDLLNQAA-LISTEEKLIVLKQVQELVINKDPSLLDNFLDEIIAFQTDKSIEVRKFVIGFIEEACKRDNELLLRLIANLNMLMRDESVNVVKKAILTLTQLYKVALQWLVRTKSVTDMQEACWDMVTQMKGDVLALLDSDNDGVRTHAIKFTESLIITLSPRTPDSDTPKKQEGDISLDKIPKDHTY--IRYDTLCEEGKTALDQLLKFMVHPAISSINLTTALGSLATLARQRPMFMSEVVQAYEMLHANLPPTLAKSQVSSVRKNLKLHLVAVLKHPSSVDFHVQISTLLQDLGMSPSEITRCTPVA---VQPRKRLHHEPYVEGKRIK--MEAVEDDED--------KEEPAPVVTPKPSSSIGTQSAIDLTAEFLLPLLTSDNVANLVLISMVYLPEVMPASFQATYTPVESAGTDAQIKHLARLMATQMTAAGLGPGLEQCKARDEEVKEEGAAGESSSKDPLIIRKLSAVSLGQAISVVGASAAYKSPIIEEAPQIKKLPEPILPSTQLKAPGASGRKKVFKLADVVQPFSEVQIEKL-ANMAIKRILYSEKAIAQTGMSHVRVKLLARLVTQFEGTKK--NDLLQFVLEDMRSRSELAFSLLYHEYNEY------LSQEPS-------GCLDSYEHCLFTLLSGLQERPEQRDGLFTKIVLEAPIITDSALEVIQRYCEDESRVYLGMSTLKELIFKRPSRQYQYLNVLLNLTSHEKEKVRSTALSFIKR-MYEKEHLKDCIEKFALTYMQFLVHPNPPSLLFGAGEDTEVAAPWTEETVRQCLYLYLSLLPLNHRLVHELAAVYTEAIADIKRSVLRVIEQPIRGMGMNSPDLLLLVENCPKGAETLVTRCLHILTDKVPPSPELVERVRDLYHKRVPDVRFLIPVINGLEKNEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HSEGSSSMSPLTPGELLIALHNIDSSKCDMKSIIKATNLCFGEKNVYTSEVLAVVMQQLMEQTPLPILLMRTVIQSLTMYPRLAGFVMNILARLILKQVWKYPKVWEGFVKCCQRTKPQSYNVLLQLPPPQLASVFERCPEMREPLLQHVHSFTPHQQAHIPTSIMTVLEA 1098
BLAST of Symplekin vs. Ensembl Zebrafish
Match: sympk (symplekin [Source:ZFIN;Acc:ZDB-GENE-060526-361]) HSP 1 Score: 610.142 bits (1572), Expect = 0.000e+0 Identity = 380/1108 (34.30%), Postives = 621/1108 (56.05%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGY-------LSLESKEKRETFQDESNSNS--ILEDFPMSGYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLPTETMQEIFHESFKRI-----LVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELIT-SDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINS 3354
+RVVDL N + EEK + + Q++EL++ K+PSLLDNF ++I+ +++ VR VI FIE ACK D++L+ + + L L+ DES NV+K+ + +Y ++L ++ KS + + + +++ +DS N G+ IK E ++I S R PDS+ PK +E D+SLDKIP D T ++ + L + G + L+K + SS ++ T L SL +A+QRP FMS V++++E+ H N+P L + QV+S+RK LK L+++LKHPS ++FH Q++TLL DLGM+ SEI R P A Q +++ E + KR + + A D D K+ AP + K S L+ E L L T NV +LVL+SM+ LPE MP +FQ+ YTP+ +AGT QI HL+RL++ Q+ +AG + + + K E ES+S I+ S + K P + P + LP+ ++ K++ +V P ++++ AN + + R +L L + G + +L+++ ++D+++R ++ SLL EY Y +S+ + Y+ L +L L + ++ F +++LEAP+IT AL +++ YC + G ++EL RP + + L ++L+ +S + +VRS ALS K + E+ + I FA T + +L+ P + + T + WT+E VR CLYL+L+L+P+NH L+H LA V+ +A +KR+++++I+ PI+ MGMNS ++L LVENC L+ R +HILTDK PSP +VE+++++YH + DVR +IP++ GL K E+I+ LPKL+ LN +V EVF RLL + SP+ P ELL+A+H ++ + ++K +I+A+ +CF EK ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+L+RLI KQVWK +W+GF++CC + QS+ VLLQLP +L SVF PE R + +++ + T Q+ H +I++++ +
Sbjct: 29 ERVVDLLNQAA-LISTEEKLIVLKQVQELVINKDPSLLDNFLDEIIAFQTDKSIEVRKFVIGFIEEACKRDNELLLRLIANLNMLMRDESVNVVKKAILTLTQLYKVALQWLVRTKSVTDMQEACWDMVTQMKGDVLALLDSDNDGVRTHAIKFTESLIITLSPRTPDSDTPKKQEGDISLDKIPKDHTY--IRYDTLCEEGKTALDQLLKFMVHPAISSINLTTALGSLATLARQRPMFMSEVVQAYEMLHANLPPTLAKSQVSSVRKNLKLHLVAVLKHPSSVDFHVQISTLLQDLGMSPSEITRCTPVA---VQPRKRLHHEPYVEGKRIK--MEAVEDDED--------KEEPAPVVTPKPSSSIGTQSAIDLTAEFLLPLLTSDNVANLVLISMVYLPEVMPASFQATYTPVESAGTDAQIKHLARLMATQMTAAGLGPGLEQCKARDEEVKEEGAAGESSSKDPLIIRKLSAVSLGQAISVVGASAAYKSPIIEEAPQIKKLPEPILPSTQLKAPGASGRKKVFKLADVVQPFSEVQIEKL-ANMAIKRILYSEKAIAQTGMSHVRVKLLARLVTQFEGTKK--NDLLQFVLEDMRSRSELAFSLLYHEYNEY------LSQEPS-------GCLDSYEHCLFTLLSGLQERPEQRDGLFTKIVLEAPIITDSALEVIQRYCEDESRVYLGMSTLKELIFKRPSRQYQYLNVLLNLTSHEKEKVRSTALSFIKR-MYEKEHLKDCIEKFALTYMQFLVHPNPPSLLFGAGEDTEVAAPWTEETVRQCLYLYLSLLPLNHRLVHELAAVYTEAIADIKRSVLRVIEQPIRGMGMNSPDLLLLVENCPKGAETLVTRCLHILTDKVPPSPELVERVRDLYHKRVPDVRFLIPVINGLEKNEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HSEGSSSMSPLTPGELLIALHNIDSSKCDMKSIIKATNLCFGEKNVYTSEVLAVVMQQLMEQTPLPILLMRTVIQSLTMYPRLAGFVMNILARLILKQVWKYPKVWEGFVKCCQRTKPQSYNVLLQLPPPQLASVFERCPEMREPLLQHVHSFTPHQQAHIPTSIMTVLEA 1098
BLAST of Symplekin vs. Ensembl Xenopus
Match: vps8 (VPS8, CORVET complex subunit [Source:Xenbase;Acc:XB-GENE-988494]) HSP 1 Score: 585.874 bits (1509), Expect = 0.000e+0 Identity = 377/1130 (33.36%), Postives = 619/1130 (54.78%), Query Frame = 1
Query: 67 SIFDRVVDLCN-STIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGY-------------LSLESKEKRETFQDESNSNSILEDFPMS--GYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLP---------------TETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELIT-SDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
S +RVV+L N + + T D+ K + Q++ELI+ K+P+LLDNF ++I+ +++ VR V++FIE ACK+D++L+ K + L L++DE+ NV+K+ M +Y ++L + + S + + ++ ++S N G+ +K +E +++ S R PDSE+PK +E D+SL++IP+D L+ L G + L+K + SS ++ L SL +IA+QRP FM+ VI+++E H N+P L + QV+S+RK LK LLS+L+HPS E+ ++TLL+DLG +Q EI R LP + S KR R E+ K++RT + L +D P++ +PS + ++ E L L + NV +LVL+SM+ LP++MP +FQ+ YTP+ +AGT QI HL+RL++ Q+ S G + E K E + +++ + +S G ++K+K + + P + ++P + T+ P TE + E+ +S K V +L E + + R +L L + L + E++ + + D + R D+ L+ L +EY Y++ A Y L+G+L L D ++ F +++LEAPL+T AL++LR YC + + G +R+L RP + + L ++LD SS + ++R +L K + E+ I FA L L+ P + + T + WT++ V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +HILTDK PSP +V++++ +YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P +LLVA+H ++ + ++K VI+A+ +CF + ++T E L++V+ QL+D LP L MRT++Q+ MYPR+ G+++N+L+RLI KQVWK +W+GFI+CC + QSF+VLLQLP +L SV + P+ R + ++ T Q H ++I++++ ++S
Sbjct: 30 STSERVVELLNMAALATNDS--KITMLKQVQELIINKDPTLLDNFLDEIIAFQADKSVEVRKFVVNFIEEACKLDNELLIKLIANLHMLLKDENVNVVKKSILTMTQLYKVALQWVARSRPPSEQQESCWDLVTEMAADILLLLESDNDGIRTHAVKFVESLIVTLSPRTPDSEVPKRQEGDISLEQIPSDHAF--LKYNTLRDVGKQAVKELLKFMAHPAISSINLTAALGSLASIARQRPMFMAEVIQAYETLHANLPPTLAKSQVSSVRKNLKLQLLSVLRHPSSYEYQGPISTLLLDLGTSQGEITRHLPPPRD-SNRKRAR-EDGEGGQKKSRTDI-------PLPDDDDDKDTIQLPTIPAPAPSTQS---ATDITAEFLRPLLSPENVANLVLISMVYLPDSMPASFQATYTPVESAGTDAQIRHLARLMATQMTSVGIGPGVEQTKDVPVDVVEEENTKPEGLVIKRRISALTKGQAISVLGCQSEKAKEEEEEEEDAPLAKKRPEPILPATQIRPSGVGGRKKVFRLKEVTEPLTEVQMKSLKLGAVQRILQAERTVGSSGASQM-----------------RVKVLARLVTQL--DISVKAEVLSHFLSDPRMRLDLALAWLYQEYCEYQSG----------------AGEEAYQECLIGILTGLQERPDQRDGVFTKVVLEAPLLTDSALDVLRKYCEDEGRSYLGMSTLRDLILTRPARQFQYLHLLLDLSSHEKDKIRQQSLHFIKR-MYEKESLRPYIEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEDTVKQCLYLYLALLPQNHKLIHELASVYTEATADIKRTVLRVIETPIRGMGMNSPELLLLVENCPKGAETLVTRCLHILTDKVPPSPELVKRVRELYHKRLPDVRFLIPVLNGLDKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEVSSSMSPLTPGDLLVALHNIDSSKCDMKSVIKATNLCFSARSVYTSEVLAVVLQQLMDTTPLPMLLMRTVIQALGMYPRLGGFIMNILTRLIYKQVWKYPKVWEGFIKCCQRTKPQSFSVLLQLPPPQLLSVLQTSPDLRDPLLVHVRAFTPHQLAHVPHSIMAILEAES 1102
BLAST of Symplekin vs. Ensembl Xenopus
Match: vps8 (VPS8, CORVET complex subunit [Source:Xenbase;Acc:XB-GENE-988494]) HSP 1 Score: 585.104 bits (1507), Expect = 0.000e+0 Identity = 377/1130 (33.36%), Postives = 619/1130 (54.78%), Query Frame = 1
Query: 67 SIFDRVVDLCN-STIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGY-------------LSLESKEKRETFQDESNSNSILEDFPMS--GYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLP---------------TETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
S +RVV+L N + + T D+ K + Q++ELI+ K+P+LLDNF ++I+ +++ VR V++FIE ACK+D++L+ K + L L++DE+ NV+K+ M +Y ++L + + S + + ++ ++S N G+ +K +E +++ S R PDSE+PK +E D+SL++IP+D L+ L G + L+K + SS ++ L SL +IA+QRP FM+ VI+++E H N+P L + QV+S+RK LK LLS+L+HPS E+ ++TLL+DLG +Q EI R LP + S KR R E+ K++RT + L +D P++ +PS + ++ E L L + NV +LVL+SM+ LP++MP +FQ+ YTP+ +AGT QI HL+RL++ Q+ S G + E K E + +++ + +S G ++K+K + + P + ++P + T+ P TE + E+ +S K V +L E + + R +L L + L + E++ + + D + R D+ L+ L +EY Y++ A Y L+G+L L D ++ F +++LEAPL+T AL++LR YC + + G +R+L RP + + L ++LD SS + ++R +L K + E+ I FA L L+ P + + T + WT++ V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +HILTDK PSP +V++++ +YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P +LLVA+H ++ + ++K VI+A+ +CF + ++T E L++V+ QL+D LP L MRT++Q+ MYPR+ G+++N+L+RLI KQVWK +W+GFI+CC + QSF+VLLQLP +L SV + P+ R + ++ T Q H ++I++++ ++S
Sbjct: 21 STSERVVELLNMAALATNDS--KITMLKQVQELIINKDPTLLDNFLDEIIAFQADKSVEVRKFVVNFIEEACKLDNELLIKLIANLHMLLKDENVNVVKKSILTMTQLYKVALQWVARSRPPSEQQESCWDLVTEMAADILLLLESDNDGIRTHAVKFVESLIVTLSPRTPDSEVPKRQEGDISLEQIPSDHAF--LKYNTLRDVGKQAVKELLKFMAHPAISSINLTAALGSLASIARQRPMFMAEVIQAYETLHANLPPTLAKSQVSSVRKNLKLQLLSVLRHPSSYEYQGPISTLLLDLGTSQGEITRHLPPPRD-SNRKRAR-EDGEGGQKKSRTDI-------PLPDDDDDKDTIQLPTIPAPAPSTQS---ATDITAEFLRPLLSPENVANLVLISMVYLPDSMPASFQATYTPVESAGTDAQIRHLARLMATQMTSVGIGPGVEQTKDVPVDVVEEENTKPEGLVIKRRISALTKGQAISVLGCQSEKAKEEEEEEEDAPLAKKRPEPILPATQIRPSGVGGRKKVFRLKEVTEPLTEVQMKSLKLGAVQRILQAERTVGSSGASQM-----------------RVKVLARLVTQL--DISVKAEVLSHFLSDPRMRLDLALAWLYQEYCEYQSG----------------AGEEAYQECLIGILTGLQERPDQRDGVFTKVVLEAPLLTDSALDVLRKYCEDEGRSYLGMSTLRDLILTRPARQFQYLHLLLDLSSHEKDKIRQQSLHFIKR-MYEKESLRPYIEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEDTVKQCLYLYLALLPQNHKLIHELASVYTEATADIKRTVLRVIETPIRGMGMNSPELLLLVENCPKGAETLVTRCLHILTDKVPPSPELVKRVRELYHKRLPDVRFLIPVLNGLDKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEVSSSMSPLTPGDLLVALHNIDSSKCDMKSVIKATNLCFSARSVYTSEVLAVVLQQLMDTTPLPMLLMRTVIQALGMYPRLGGFIMNILTRLIYKQVWKYPKVWEGFIKCCQRTKPQSFSVLLQLPPPQLLSVLQTSPDLRDPLLVHVRAFTPHQLAHVPHSIMAILEAES 1093
BLAST of Symplekin vs. Ensembl Xenopus
Match: vps8 (VPS8, CORVET complex subunit [Source:Xenbase;Acc:XB-GENE-988494]) HSP 1 Score: 575.859 bits (1483), Expect = 0.000e+0 Identity = 365/1110 (32.88%), Postives = 604/1110 (54.41%), Query Frame = 1
Query: 124 EEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGY-------------LSLESKEKRETFQDESNSNSILEDFPMS--GYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLP---------------TETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELIT-SDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
+ K + Q++ELI+ K+P+LLDNF ++I+ +++ VR V++FIE ACK+D++L+ K + L L++DE+ NV+K+ M +Y ++L + + S + + ++ ++S N G+ +K +E +++ S R PDSE+PK +E D+SL++IP+D L+ L G + L+K + SS ++ L SL +IA+QRP FM+ VI+++E H N+P L + QV+S+RK LK LLS+L+HPS E+ ++TLL+DLG +Q EI R LP + + RKR E+ ++ + L +D P++ +PS + ++ E L L + NV +LVL+SM+ LP++MP +FQ+ YTP+ +AGT QI HL+RL++ Q+ S G + E K E + +++ + +S G ++K+K + + P + ++P + T+ P TE + E+ +S K V +L E + + R +L L + L + E++ + + D + R D+ L+ L +EY Y++ A Y L+G+L L D ++ F +++LEAPL+T AL++LR YC + + G +R+L RP + + L ++LD SS + ++R +L K + E+ I FA L L+ P + + T + WT++ V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +HILTDK PSP +V++++ +YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P +LLVA+H ++ + ++K VI+A+ +CF + ++T E L++V+ QL+D LP L MRT++Q+ MYPR+ G+++N+L+RLI KQVWK +W+GFI+CC + QSF+VLLQLP +L SV + P+ R + ++ T Q H ++I++++ ++S
Sbjct: 8 DSKITMLKQVQELIINKDPTLLDNFLDEIIAFQADKSVEVRKFVVNFIEEACKLDNELLIKLIANLHMLLKDENVNVVKKSILTMTQLYKVALQWVARSRPPSEQQESCWDLVTEMAADILLLLESDNDGIRTHAVKFVESLIVTLSPRTPDSEVPKRQEGDISLEQIPSDHAF--LKYNTLRDVGKQAVKELLKFMAHPAISSINLTAALGSLASIARQRPMFMAEVIQAYETLHANLPPTLAKSQVSSVRKNLKLQLLSVLRHPSSYEYQGPISTLLLDLGTSQGEITRHLPPPRDSN---RKRAREDGEGGQK--------KSHIPLPDDDDDKDTIQLPTIPAPAPSTQS---ATDITAEFLRPLLSPENVANLVLISMVYLPDSMPASFQATYTPVESAGTDAQIRHLARLMATQMTSVGIGPGVEQTKDVPVDVVEEENTKPEGLVIKRRISALTKGQAISVLGCQSEKAKEEEEEEEDAPLAKKRPEPILPATQIRPSGVGGRKKVFRLKEVTEPLTEVQMKSLKLGAVQRILQAERTVGSSGASQM-----------------RVKVLARLVTQL--DISVKAEVLSHFLSDPRMRLDLALAWLYQEYCEYQSG----------------AGEEAYQECLIGILTGLQERPDQRDGVFTKVVLEAPLLTDSALDVLRKYCEDEGRSYLGMSTLRDLILTRPARQFQYLHLLLDLSSHEKDKIRQQSLHFIKR-MYEKESLRPYIEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEDTVKQCLYLYLALLPQNHKLIHELASVYTEATADIKRTVLRVIETPIRGMGMNSPELLLLVENCPKGAETLVTRCLHILTDKVPPSPELVKRVRELYHKRLPDVRFLIPVLNGLDKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEVSSSMSPLTPGDLLVALHNIDSSKCDMKSVIKATNLCFSARSVYTSEVLAVVLQQLMDTTPLPMLLMRTVIQALGMYPRLGGFIMNILTRLIYKQVWKYPKVWEGFIKCCQRTKPQSFSVLLQLPPPQLLSVLQTSPDLRDPLLVHVRAFTPHQLAHVPHSIMAILEAES 1060
BLAST of Symplekin vs. Ensembl Xenopus
Match: vps8 (VPS8, CORVET complex subunit [Source:Xenbase;Acc:XB-GENE-988494]) HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0 Identity = 371/1125 (32.98%), Postives = 612/1125 (54.40%), Query Frame = 1
Query: 82 VVDLCN-STIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGY-------------LSLESKEKRETFQDESNSNSILEDFPMS--GYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLP---------------TETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELIT-SDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
VV+L N + + T D+ K + Q++ELI+ K+P+LLDNF ++I+ +++ VR V++FIE ACK+D++L+ K + L L++DE+ NV+K+ M +Y ++L + + S + + ++ ++S N G+ +K +E +++ S R PDSE+PK +E D+SL++IP+D L+ L G + L+K + SS ++ L SL +IA+QRP FM+ VI+++E H N+P L + QV+S+RK LK LLS+L+HPS E+ ++TLL+DLG +Q EI R LP + + RKR E+ ++ L +D P++ +PS + ++ E L L + NV +LVL+SM+ LP++MP +FQ+ YTP+ +AGT QI HL+RL++ Q+ S G + E K E + +++ + +S G ++K+K + + P + ++P + T+ P TE + E+ +S K V +L E + + R +L L + L + E++ + + D + R D+ L+ L +EY Y++ A Y L+G+L L D ++ F +++LEAPL+T AL++LR YC + + G +R+L RP + + L ++LD SS + ++R +L K + E+ I FA L L+ P + + T + WT++ V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +HILTDK PSP +V++++ +YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P +LLVA+H ++ + ++K VI+A+ +CF + ++T E L++V+ QL+D LP L MRT++Q+ MYPR+ G+++N+L+RLI KQVWK +W+GFI+CC + QSF+VLLQLP +L SV + P+ R + ++ T Q H ++I++++ ++S
Sbjct: 19 VVELLNMAALATNDS--KITMLKQVQELIINKDPTLLDNFLDEIIAFQADKSVEVRKFVVNFIEEACKLDNELLIKLIANLHMLLKDENVNVVKKSILTMTQLYKVALQWVARSRPPSEQQESCWDLVTEMAADILLLLESDNDGIRTHAVKFVESLIVTLSPRTPDSEVPKRQEGDISLEQIPSDHAF--LKYNTLRDVGKQAVKELLKFMAHPAISSINLTAALGSLASIARQRPMFMAEVIQAYETLHANLPPTLAKSQVSSVRKNLKLQLLSVLRHPSSYEYQGPISTLLLDLGTSQGEITRHLPPPRDSN---RKRAREDGEGGQKKNIP---------LPDDDDDKDTIQLPTIPAPAPSTQS---ATDITAEFLRPLLSPENVANLVLISMVYLPDSMPASFQATYTPVESAGTDAQIRHLARLMATQMTSVGIGPGVEQTKDVPVDVVEEENTKPEGLVIKRRISALTKGQAISVLGCQSEKAKEEEEEEEDAPLAKKRPEPILPATQIRPSGVGGRKKVFRLKEVTEPLTEVQMKSLKLGAVQRILQAERTVGSSGASQV---------------IMRVKVLARLVTQL--DISVKAEVLSHFLSDPRMRLDLALAWLYQEYCEYQSG----------------AGEEAYQECLIGILTGLQERPDQRDGVFTKVVLEAPLLTDSALDVLRKYCEDEGRSYLGMSTLRDLILTRPARQFQYLHLLLDLSSHEKDKIRQQSLHFIKR-MYEKESLRPYIEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEDTVKQCLYLYLALLPQNHKLIHELASVYTEATADIKRTVLRVIETPIRGMGMNSPELLLLVENCPKGAETLVTRCLHILTDKVPPSPELVKRVRELYHKRLPDVRFLIPVLNGLDKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEVSSSMSPLTPGDLLVALHNIDSSKCDMKSVIKATNLCFSARSVYTSEVLAVVLQQLMDTTPLPMLLMRTVIQALGMYPRLGGFIMNILTRLIYKQVWKYPKVWEGFIKCCQRTKPQSFSVLLQLPPPQLLSVLQTSPDLRDPLLVHVRAFTPHQLAHVPHSIMAILEAES 1085
BLAST of Symplekin vs. Ensembl Xenopus
Match: vps8 (VPS8, CORVET complex subunit [Source:Xenbase;Acc:XB-GENE-988494]) HSP 1 Score: 571.237 bits (1471), Expect = 0.000e+0 Identity = 371/1125 (32.98%), Postives = 611/1125 (54.31%), Query Frame = 1
Query: 82 VVDLCN-STIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGY-------------LSLESKEKRETFQDESNSNSILEDFPMS--GYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLP---------------TETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELIT-SDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
VV+L N + + T D+ K + Q++ELI+ K+P+LLDNF ++I+ +++ VR V++FIE ACK+D++L+ K + L L++DE+ NV+K+ M +Y ++L + + S + + ++ ++S N G+ +K +E +++ S R PDSE+PK +E D+SL++IP+D L+ L G + L+K + SS ++ L SL +IA+QRP FM+ VI+++E H N+P L + QV+S+RK LK LLS+L+HPS E+ ++TLL+DLG +Q EI R LP + ++ KRAR +D+I P++ +PS + ++ E L L + NV +LVL+SM+ LP++MP +FQ+ YTP+ +AGT QI HL+RL++ Q+ S G + E K E + +++ + +S G ++K+K + + P + ++P + T+ P TE + E+ +S K V +L E + + R +L L + L + E++ + + D + R D+ L+ L +EY Y++ A Y L+G+L L D ++ F +++LEAPL+T AL++LR YC + + G +R+L RP + + L ++LD SS + ++R +L K + E+ I FA L L+ P + + T + WT++ V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +HILTDK PSP +V++++ +YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P +LLVA+H ++ + ++K VI+A+ +CF + ++T E L++V+ QL+D LP L MRT++Q+ MYPR+ G+++N+L+RLI KQVWK +W+GFI+CC + QSF+VLLQLP +L SV + P+ R + ++ T Q H ++I++++ ++S
Sbjct: 3 VVELLNMAALATNDS--KITMLKQVQELIINKDPTLLDNFLDEIIAFQADKSVEVRKFVVNFIEEACKLDNELLIKLIANLHMLLKDENVNVVKKSILTMTQLYKVALQWVARSRPPSEQQESCWDLVTEMAADILLLLESDNDGIRTHAVKFVESLIVTLSPRTPDSEVPKRQEGDISLEQIPSDHAF--LKYNTLRDVGKQAVKELLKFMAHPAISSINLTAALGSLASIARQRPMFMAEVIQAYETLHANLPPTLAKSQVSSVRKNLKLQLLSVLRHPSSYEYQGPISTLLLDLGTSQGEITRHLPPPRDSNR-------------KRARE-------------DDTI----QLPTIPAPAPSTQS---ATDITAEFLRPLLSPENVANLVLISMVYLPDSMPASFQATYTPVESAGTDAQIRHLARLMATQMTSVGIGPGVEQTKDVPVDVVEEENTKPEGLVIKRRISALTKGQAISVLGCQSEKAKEEEEEEEDAPLAKKRPEPILPATQIRPSGVGGRKKVFRLKEVTEPLTEVQMKSLKLGAVQRILQAERTVGSSGASQV---------------IMRVKVLARLVTQL--DISVKAEVLSHFLSDPRMRLDLALAWLYQEYCEYQSG----------------AGEEAYQECLIGILTGLQERPDQRDGVFTKVVLEAPLLTDSALDVLRKYCEDEGRSYLGMSTLRDLILTRPARQFQYLHLLLDLSSHEKDKIRQQSLHFIKR-MYEKESLRPYIEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEDTVKQCLYLYLALLPQNHKLIHELASVYTEATADIKRTVLRVIETPIRGMGMNSPELLLLVENCPKGAETLVTRCLHILTDKVPPSPELVKRVRELYHKRLPDVRFLIPVLNGLDKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEVSSSMSPLTPGDLLVALHNIDSSKCDMKSVIKATNLCFSARSVYTSEVLAVVLQQLMDTTPLPMLLMRTVIQALGMYPRLGGFIMNILTRLIYKQVWKYPKVWEGFIKCCQRTKPQSFSVLLQLPPPQLLSVLQTSPDLRDPLLVHVRAFTPHQLAHVPHSIMAILEAES 1051
BLAST of Symplekin vs. Ensembl Mouse
Match: Sympk (symplekin [Source:MGI Symbol;Acc:MGI:1915438]) HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0 Identity = 401/1128 (35.55%), Postives = 621/1128 (55.05%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSS-KRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSL--ESKEKRETFQDES----NSNSILEDFPMSGYANQKSKNQMTL---------LKKHP--------------FSTQKPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINS 3354
+RVVDL N + + K + Q++ELI+ K+P+LLDNF ++I+ +++ VR VI FIE ACK D +L+ K + L L+ DE+ NV+K+ M +Y ++L +K S D++ + C +V ++ ++ DS N G+ IK +E +++ S R DSE+P+ +E+D+SLD+IP D P +Q +L + G L+K + SS ++ T L SL NIA+QRP FMS VI+++E H N+P L + QV+S+RK LK LLS+LKHP+ LEF +Q+TTLL+DLG Q+EI R +P S+ RKR ++ S+ K+ + N D D PS K+ + ++ E L L T NV +LVL+SM+ LPETMP +FQ+ YTP+ +AGT+ QI HL+RL++ Q+ +AG ++K+ +E ++E S I + G A +Q T+ K+ P +K F L V K L ++ + + KRIL RA + + R IL SL + G E++ + ++DV+ R D+ + L +EY +Y A + T+ Y+ L+ +L L D K+ F +++LEAPLIT AL ++R YC + A G + +L RP + + L ++LD SS + VRS AL K + E E + FA L L+ P + + T + WT+E V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +H LTDK PSP +V++++++YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P ELL+A+H ++ ++K +I+A+ +CF E+ ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+L+RLI KQVWK +W+GFI+CC + QSF V+LQLP +L +VF+ PE R + ++ + T Q+ H N+I++++ +
Sbjct: 34 ERVVDLLNQAA-LITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVK--SRVISDLQ--EACWDMVSSMAGEIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEVPRRQEHDISLDRIPRDH--PYIQYNVLWEEGKAAVEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPS----SKDSRKRPRDDTDSTLKKMKLEPNLGEDDEDKDLE-------PGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPETMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKPESVLIKRRLSVQGQAISVVGSQSTMSPLEEEVPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLKPLTDAQVEAMKLGAVKRIL------------RAEKAVACSGAAQV----------RIKILASLVTQFDSG--FKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGTS-------------GTLDKYEDCLICLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVIRKYCEDESRAYLGMSTLGDLIFKRPSRQFQYLHVLLDLSSHEKDRVRSQALLFIKR-MYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEGNSALSPLNPGELLIALHNIDSVKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILARLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMTILEA 1100
BLAST of Symplekin vs. Ensembl Mouse
Match: Sympk (symplekin [Source:MGI Symbol;Acc:MGI:1915438]) HSP 1 Score: 113.62 bits (283), Expect = 1.210e-28 Identity = 51/108 (47.22%), Postives = 76/108 (70.37%), Query Frame = 1
Query: 2989 ERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQ 3312
E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+L+RLI KQVWK +W+GFI+CC + QSF V+LQLP +L +VF+ PE R + ++ + T Q
Sbjct: 3 EVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILARLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQ 110
BLAST of Symplekin vs. Ensembl Mouse
Match: Sympk (symplekin [Source:MGI Symbol;Acc:MGI:1915438]) HSP 1 Score: 115.546 bits (288), Expect = 2.552e-28 Identity = 68/191 (35.60%), Postives = 113/191 (59.16%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPAD 636
+RVVDL N + + K + Q++ELI+ K+P+LLDNF ++I+ +++ VR VI FIE ACK D +L+ K + L L+ DE+ NV+K+ M +Y ++L + KS D++ + C +V ++ ++ DS N G+ IK +E +++ S R DSE+P+ +E+D+SLD+IP D
Sbjct: 34 ERVVDLLNQA-ALITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMV--KSRVISDLQ--EACWDMVSSMAGEIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEVPRRQEHDISLDRIPRD 219
BLAST of Symplekin vs. Ensembl Mouse
Match: Sympk (symplekin [Source:MGI Symbol;Acc:MGI:1915438]) HSP 1 Score: 87.0409 bits (214), Expect = 8.197e-19 Identity = 56/170 (32.94%), Postives = 95/170 (55.88%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRF 573
+RVVDL N + + K + Q++ELI+ K+P+LLDNF ++I+ +++ VR VI FIE ACK D +L+ K + L L+ DE+ NV+K+ M +Y ++L + KS D++ + C +V ++ ++ DS N G+ IK +E +++ S R
Sbjct: 34 ERVVDLLNQA-ALITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMV--KSRVISDLQ--EACWDMVSSMAGEIILLLDSDNDGIRTHAIKFVEGLIVTLSPRM 198
BLAST of Symplekin vs. UniProt/SwissProt
Match: sp|Q92797|SYMPK_HUMAN (Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2) HSP 1 Score: 639.802 bits (1649), Expect = 0.000e+0 Identity = 397/1112 (35.70%), Postives = 628/1112 (56.47%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSS-KRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSL--ESKEKRETFQDES--NSNSILEDFPMSGYANQ----KSKNQMTLLKKH-PFSTQKPFNLESVT--KTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
+RVVDL N + + K + Q++ELI+ K+P+LLDNF ++I+ +++ VR VI FIE ACK D +L+ K + L L+ DE+ NV+K+ M +Y ++L +K + S E + C +V A+ + DS N G+ IK +E +++ S R DSEIP+ +E+D+SLD+IP D P +Q +L + G L+K + SS ++ T L SL NIA+QRP FMS VI+++E H N+P L + QV+S+RK LK LLS+LKHP+ LEF +Q+TTLL+DLG Q+EI R +P + + RKR +++ S+ K+ + N D D PS K+ + ++ E L L T NV +LVL+SM+ LPE MP +FQ+ YTP+ +AGT+ QI HL+RL++ Q+ +AG ++K+ +E ++E + S+L +S S + M+ L++ P + ++P + VT + ++IF S ++ PL + +++ + + + R IL SL + G L E++ + ++DV+ R D+ + L +EY +Y A + ++ Y+ L+ +L L D K+ F +++LEAPLIT AL ++R YC + G +R+L RP + + L ++LD SS + +VRS AL K + E E + FA L L+ P + + T + WT+E V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +H LTDK PSP +V++++++YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P ELL+A+H ++ ++K +I+A+ +CF E+ ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+LSRLI KQVWK +W+GFI+CC + QSF V+LQLP +L +VF+ PE R + ++ + T Q+ H N+I++++ +
Sbjct: 34 ERVVDLLNQAA-LITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVIS----ELQEACWDMVSAMAGDIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEIPRRQEHDISLDRIPRDH--PYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDT----RKRPRDDSDSTLKKMKLEPNLGEDDEDKDLE-------PGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPEAMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKTESVLIKRRLSAQGQAISVVGSLSSMSPLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSD---VLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQV-RIKILASLVTQFNSG--LKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGAS-------------GSLDKYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVVRKYCEDESRTYLGMSTLRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKR-MYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEGNSALSPLNPGELLIALHNIDSVKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMTILEASG 1102
BLAST of Symplekin vs. UniProt/SwissProt
Match: sp|Q80X82|SYMPK_MOUSE (Symplekin OS=Mus musculus OX=10090 GN=Sympk PE=1 SV=2) HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0 Identity = 401/1128 (35.55%), Postives = 621/1128 (55.05%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSS-KRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSL--ESKEKRETFQDES----NSNSILEDFPMSGYANQKSKNQMTL---------LKKHP--------------FSTQKPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINS 3354
+RVVDL N + + K + Q++ELI+ K+P+LLDNF ++I+ +++ VR VI FIE ACK D +L+ K + L L+ DE+ NV+K+ M +Y ++L +K S D++ + C +V ++ ++ DS N G+ IK +E +++ S R DSE+P+ +E+D+SLD+IP D P +Q +L + G L+K + SS ++ T L SL NIA+QRP FMS VI+++E H N+P L + QV+S+RK LK LLS+LKHP+ LEF +Q+TTLL+DLG Q+EI R +P S+ RKR ++ S+ K+ + N D D PS K+ + ++ E L L T NV +LVL+SM+ LPETMP +FQ+ YTP+ +AGT+ QI HL+RL++ Q+ +AG ++K+ +E ++E S I + G A +Q T+ K+ P +K F L V K L ++ + + KRIL RA + + R IL SL + G E++ + ++DV+ R D+ + L +EY +Y A + T+ Y+ L+ +L L D K+ F +++LEAPLIT AL ++R YC + A G + +L RP + + L ++LD SS + VRS AL K + E E + FA L L+ P + + T + WT+E V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +H LTDK PSP +V++++++YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P ELL+A+H ++ ++K +I+A+ +CF E+ ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+L+RLI KQVWK +W+GFI+CC + QSF V+LQLP +L +VF+ PE R + ++ + T Q+ H N+I++++ +
Sbjct: 34 ERVVDLLNQAA-LITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVK--SRVISDLQ--EACWDMVSSMAGEIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEVPRRQEHDISLDRIPRDH--PYIQYNVLWEEGKAAVEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPS----SKDSRKRPRDDTDSTLKKMKLEPNLGEDDEDKDLE-------PGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPETMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKPESVLIKRRLSVQGQAISVVGSQSTMSPLEEEVPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLKPLTDAQVEAMKLGAVKRIL------------RAEKAVACSGAAQV----------RIKILASLVTQFDSG--FKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGTS-------------GTLDKYEDCLICLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVIRKYCEDESRAYLGMSTLGDLIFKRPSRQFQYLHVLLDLSSHEKDRVRSQALLFIKR-MYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEGNSALSPLNPGELLIALHNIDSVKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILARLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMTILEA 1100
BLAST of Symplekin vs. UniProt/SwissProt
Match: sp|Q8MSU4|SYMPK_DROME (Symplekin OS=Drosophila melanogaster OX=7227 GN=Sym PE=1 SV=1) HSP 1 Score: 424.861 bits (1091), Expect = 2.169e-127 Identity = 320/1136 (28.17%), Postives = 562/1136 (49.47%), Query Frame = 1
Query: 79 RVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLS---SKRARTSVNAHSDYS---DLTYNDSIIKKFAAPSLEQK--SPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLV------SAGYLSLESKEKRETFQ-----------DESNSNSILED-FPMSGYANQK-------SKNQMTLLKKHPFSTQKPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITSDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSI--HPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSL-IHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPL--MVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSN---AILSLINSDSV 3363
+VVD CN + K + +++E ++ L + F E +L L + N VR V+ F+E CKV +L+ + + L+ D S V+KR+ A +IY L L +A+ +I ++ +D+ N G+ IK +E +V+LQS F D + K ++ D SL +P T+ + E L++ G + ++L++ H SS ++ +SL IAK RP FM V+E+F+ + N+P L + QV+S+RK+LK L +LLK+ EF S + +L+DLG + +EI + +PK D+ +R+++ N + +KRAR + +L + +K + + +K + R P V L E LP L P +P F YTPI Q Q+ ++SR QL A S E + + Q DE + E+ F A +K +K + T+++K K L+ +TK LP ++ ++ +RIL N ++C + S+ L ++ +A F Y ++++ ++D+K R D+ S L +EY+ + + EN P A + ++ G+ + D K R+ LEAP++ ++ L + +G ++I++L RP + + ++L+FS + +++R A + + + I +FA L ++ Q P ++ T P DW ++ + C L L+P + + + +VFV +KRTI++ +DIPIK+MG+ S +L+L+E+C L+IR+I+ILT++ +PSP +V +++++Y NK DVR++IP+L GLT++E+I +LPKL+ LN +V EVF RLL + A +F +T + P ++LVA+H ++ + ++K +++A+ +C E+ ++TQE L V+ QL+++ LPTL MRT +QS ++YPR+ +V+N+L RLI KQVW+ +W+GF++ +L QS +LL LP +L P+ R + Y ++ Q + ++ S +L +I+ SV
Sbjct: 29 KVVDWCNELV-IASPSTKCELLAKVQETVLGSCAELAEEFLESVLSLAHDSNMEVRKQVVAFVEQVCKVKVELLPHVINVVSMLLRDNSAQVIKRVIQACGSIYKNGLQYLCSLMEPGDSAEQAWNILSLIKAQILDMIDNENDGIRTNAIKFLEGVVVLQS--FADEDSLK-RDGDFSLADVPDHCTL--FRREKLQEEGNNILDILLQFHGTTHISSVNLIACTSSLCTIAKMRPIFMGAVVEAFKQLNANLPPTLTDSQVSSVRKSLKMQLQTLLKNRGAFEFASTIRGMLVDLGSSTNEIQKLIPKMDKQEMARRQKRILENAAQSLAKRARLACEQQDQQQREMELDTEELERQKQKSTRVNEKFLAEHFRNPETVVTLVLEFLPSL-----------------PTEVPQKFLQEYTPIREMSIQQQVTNISRFFGEQLSEKRLGPGAATFSREPPMRVKKVQAIESTLTAMEVDEDAVQKLSEEEFQRKEEATKKLRETMERAKGEQTVIEKMK-ERAKTLKLQEITKPLPRNLKEKFLTDAVRRIL------NSERQC-----------------IKGGVSSKRRKLVTVIAATFPDNVRYG-IMEFILEDIKQRIDLAFSWLFEEYSLLQGFTRHTYVKTENR--PDHAYNELLNKLIFGIGERCDHKD-KIILIRRVYLEAPILPEVSIGHLVQLSLDDEFSQHGLELIKDLAVLRPPRKNRFVRVLLNFSVHERLDLRDLAQAHLVSLYHVHKILPARIDEFALEWLKFIEQESPPAAVFSQDFGRPTEEP-DWREDTTKVCFGLAFTLLPYKPEVYLQQICQVFVSTSAELKRTILRSLDIPIKKMGVESPTLLQLIEDCPKGMETLVIRIIYILTER-VPSPHEELVRRVRDLYQNKVKDVRVMIPVLSGLTRSELISVLPKLIKLNPAVVKEVFNRLLGIGA------EFAHQTMAMTPTDILVALHTIDTSVCDIKAIVKATSLCLAERDLYTQEVLMAVLQQLVEVTPLPTLMMRTTIQSLTLYPRLANFVMNLLQRLIIKQVWRQKVIWEGFLKTVQRLKPQSMPILLHLPPAQLVDALQQCPDLRPALSEYAES-MQDEPMNGSGITQQVLDIISGKSV 1104
BLAST of Symplekin vs. UniProt/SwissProt
Match: sp|Q7ZYV9|SYMPK_XENLA (Symplekin OS=Xenopus laevis OX=8355 GN=sympk PE=1 SV=1) HSP 1 Score: 355.525 bits (911), Expect = 3.884e-102 Identity = 195/519 (37.57%), Postives = 310/519 (59.73%), Query Frame = 1
Query: 1807 ELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELIT-SDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
E++ + + D + R D+ L+ L +EY Y++ A Y L+G+L L D ++ F +++LEAPL+T AL++LR YC + + G +R+L RP + + L ++LD SS + ++R +L K + E+ I FA L L+ P + + T + WT++ V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +HILTDK PSP +V++++ +YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P +LLVA+H ++ + ++K VI+A+ +CF + ++T E L++V+ QL+D LP L MRT++Q+ MYPR+ G+++N+L+RLI KQVWK +W+GFI+CC + QSF+VLLQLP +L SV + P+ R + ++ T Q H ++I++++ ++S
Sbjct: 597 EVLSHFLNDPRMRLDLALAWLYQEYCEYQSG----------------AGEEGYQECLIGILTGLQERPDQRDGVFTKVVLEAPLLTDSALDVLRKYCEDEGRSYLGMSTLRDLILTRPARQFQYLHLLLDLSSHEKDKIRQQSLHFIKR-MYEKESLRPYIEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEDTVKQCLYLYLALLPQNHKLIHELASVYTEATADIKRTVLRVIETPIRGMGMNSPELLLLVENCPKGAETLVTRCLHILTDKVPPSPELVKRVRELYHKRLPDVRFLIPVLNGLDKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEVSSSLSPLTPGDLLVALHNIDSSKCDMKSVIKATNLCFSARSVYTSEVLAVVLQQLMDTTPLPMLLMRTVIQALGMYPRLGGFIMNILTRLIYKQVWKYPKVWEGFIKCCQRTKPQSFSVLLQLPPPQLLSVLQTSPDLRDPLLAHVRAFTPHQLAHVPHSIMAILEAES 1093 HSP 2 Score: 251.906 bits (642), Expect = 4.769e-67 Identity = 157/445 (35.28%), Postives = 259/445 (58.20%), Query Frame = 1
Query: 67 SIFDRVVDLCN-STIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAG 1398
S +RVV+L N + + T D K + Q++ELI+ K+P+LLDNF ++I+ +++ VR V++FIE ACK+D++L+ K + L L++DE+ NV+K+ M +Y ++L + + S + + ++ ++S N GM +K +E +++ S R DSE+PK ++ D+SL++IP D L+ L G + L+K + SS ++ L SL +IA+QRP FM+ VI+++E H N+P L + QV+S+RK LK LLS+L+HPS E+ ++TLL+DLG +Q EI R LP + S KR R E+ K++RT + L +D P++ +PS + ++ + + L + NV +LVL+SM+ LP++MP +FQS YTP+ +AGT +QI HL+RL++ Q+ +AG
Sbjct: 21 STSERVVELLNMAALATNDT--KITMLKQVQELIINKDPTLLDNFLDEIIAFQADKSVEVRKIVVNFIEEACKLDNELLIKLIANLHMLLKDENVNVVKKSILTMTQLYKVALQWVARSRPPSEQQESCWDLVTEMAADILLLLESDNDGMRTHAVKFVESLIVTLSPRTADSEVPKRQDGDISLEQIPPDHQF--LKYNTLRDLGKQAVKELLKFMAHPAISSINLTAALGSLASIARQRPMFMAEVIQAYETLHANLPPTLAKSQVSSVRKNLKLQLLSVLRHPSSYEYQGPISTLLLDLGTSQGEITRHLPPPRD-SNRKRAR-EDGEGGQKKSRTDI-------PLPDDDDDKDTMQLPTIPAPAPSTQS---ATDITADFVRPLLSPENVANLVLISMVYLPDSMPASFQSTYTPVESAGTDSQIRHLARLMATQMSAAG 449
BLAST of Symplekin vs. TrEMBL
Match: A0A2T7PFV1 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_07725 PE=4 SV=1) HSP 1 Score: 673.7 bits (1737), Expect = 0.000e+0 Identity = 420/1137 (36.94%), Postives = 658/1137 (57.87%), Query Frame = 1
Query: 79 RVVDLCN-STIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTS-----VNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGY------LSLES-------KEKRET--FQDES---NSNS---ILEDFPM-------SGYANQKSKNQMTLLKKHPF--STQKP--------FNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTAT--PRLATISDYDAVLVGVLKELIT-SDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLI 3348
+VVDL N +++ T D E+ L + Q++ELI++K+P LLDNF ++++ +R+ +V+ +I F+E ACK D + + + + L L DE+ NV K++ + TIY +L K KS ++ +++ I ++ +DS N G+ ++K +E + + S++ P+SE+PK +E DLSLD++ + + ++++ LE+ G F L++ H SS ++ T++ +LTNIA+QRPQF +V++ FE HVN+P L + QV+S+RK LK +L LL+HP +F Q+TTLL DLG TQSEI +ALPK + KRK +E + K+A+T ++ D + D K+ P+ SL++ ++ +++LLP+L +V +V DLVLLSM+MLPE MP FQS YTPIAAAGT QI H+SRLL+ QL AG L L++ K+ ET + D S NS+S ++ P+ G ++ + + +K+ F T P F LESVTK L +ET+ + FKRIL + + N +R IL+ L S FGG L L Y D++NRYD+ S L +EYT+ + Y N+A+ + A +S YD L +LK L D K+ F R++LEAP+IT A+ I+R +C+ + + + G + +R+L RP +R + + ++L F++ + E+R+ A+ A+ L ++ I +A L LL+ +P S + W +E ++ LYL+L L+P NH+LIH LA ++ +KRTI+++++ P+K MGM+S E+LRLVENC L++RVIHILTDKA+PSP +V+ ++++YH + DVR +IP+L GL+K E+I LPKL+ LN +V EVF RL+ A +V SP+ P+ELLVA+H ++ ++K +I+A+ MCF E+ I+TQE L+IV+ +L++ LPTL MRT++QS SMYPR++G+V+N+L RLI KQVW +W+GFI+CC + QSF VLLQLP +L +VF P+ R + ++ + T Q H I+ ++
Sbjct: 7 QVVDLLNRASVLTKDNEKTGL-LKQVQELIIHKDPELLDNFLDEMIAFQTDRSVDVKKCIIGFMEEACKKDPECLPRVMPSLAHLFADENINVQKKVILSFATIYRSALQWVSKAKSVRSEMTAVWEHVNQIKSRMVEMLDSDNDGVRTHIVKFLEGLTLALSKKSPESEMPKKQEGDLSLDQVMENNRL--IRLKKLEEEGQTSFLTLLQFQGSLHISSINLMTVMGALTNIARQRPQFFDQVVQGFEALHVNLPPTLAKSQVSSVRKNLKMQMLMLLRHPMSADFVPQITTLLTDLGATQSEINKALPKEE---SRKRKTEEPGPSALKKAKTEPLLPEIDDDDDIGMTPWTDRTRKQ---PT------SLQRQTAIDITAEDLLPRL-SVQHVADLVLLSMVMLPEAMPAQFQSTYTPIAAAGTDAQIKHISRLLATQLTMAGMGKGVGELKLQAMKKVDDQKDGGETPAYDDGSTSPNSSSRLWLILFLPVDMFITVTGGLTAREEEERAEHMKRTDFLPPTSAPLPRKGLRQFKLESVTKPLDSETLDAMTVAIFKRIL------DSERMASVNHIQG----------------ARTKILSCLTSQ-FGGC-LKDILEGYIFDDLRNRYDLAFSWLYQEYTNCQNY---------NSASIPGKAADMSSYDECLTRLLKGLSEMPDQKDGLFHRLILEAPVITDNAMQIIRKFCANEAHTEAGMKTLRDLIMMRPKNRLDFMDVMLTFTASERPEIRNPAIQTAQ-KLYENKQLRPSIEFYAIKQLKQLLETRPETSADQKRWQGGNAESWGEESIKAHLYLYLGLLPANHALIHELANIYTATSADIKRTILRVLEGPVKGMGMDSPELLRLVENCPKGSETLVMRVIHILTDKAVPSPELVDHIRDLYHKRVPDVRFLIPVLNGLSKKEVIAALPKLIKLNPMVVKEVFNRLM--GAHITANASYV---SPLTPDELLVALHNIDPLKCDMKTIIKAANMCFSERSIYTQEVLAIVMQRLMEQTPLPTLLMRTVIQSLSMYPRLIGFVLNILQRLILKQVWNQKKVWEGFIKCCQRTKPQSFQVLLQLPPAQLSNVFQISPDLRIPLLTHVRSFTPLQLAHIPPEIMHVL 1088
BLAST of Symplekin vs. TrEMBL
Match: A0A210PW07 (Symplekin OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT09900 PE=4 SV=1) HSP 1 Score: 672.929 bits (1735), Expect = 0.000e+0 Identity = 413/1121 (36.84%), Postives = 637/1121 (56.82%), Query Frame = 1
Query: 67 SIFDRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKG--KENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLT-YNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSLESKEKRETFQDESNSN-------------------SILEDFPMSGYANQKSKNQMTLLKKHPFSTQ-KPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSD 3357
S +DRVVDL N +K + Q++ELI++KEP+LLDNF +++L +R +VR VI F+E ACK D +L+ K + L+ L+EDE+ N+ K++ M +Y L K + + + ++ + L+ DS N G+ ++K +E +V++ S +SE PK E+D++L +P D L+++ LE G +F ++ H SS ++ T++ S+T IAKQRP F +V+++FE VN+P L + QV+S+RK LK +LSLL+H ++ +Q+TTLL DLG T SE+++A+PK DE KRK +E ++ K V D + +T + D K +AP+++Q+S + V+ S++L +LN NV DLVL+SM+MLP+TMP FQS YTPIAAAGT+ QI H++RLLS QL +AG ++ + ++ ++E + +D P A S ++ P K F L SVT+ L + + ++ + RIL N E + N +P +R +L L S FGG EL L +Y +D+++R+D+ + L +EY + + + K + P LA+ YD L +L L+ D+KE +F R+L+EAP +T A+ IL+ YC + G ++EL RP HR L ++L+ S D EVRS A+ K L + I ++A L YLL KP + + P +P W +++++ CLYL+L L+P NH LI LA V+ A +KRTI+++++ P+K MGM S E+L LVENC L+ RVIHILTDKA PS +VE+++++YH + DVR +IP+L GL K E+I LPKL+ LN +V EVF RLL + F +SP+ P ELL+++H ++ ++K +I+A+ +CF EK ++TQE L++V+ L++ LPTLFMRT++QS SMYPR++G+V+N+L RLI KQVWK +W+GFI+CC + QSF VLLQLP +L+SVF S PE R + ++ + T+ Q H AI++++ D
Sbjct: 26 STYDRVVDLINKASLMQKDAQKINNLKQVQELIIHKEPNLLDNFLDEMLAFQSDRTVDVRKFVISFMEEACKKDMELLPKILPCLQLLLEDENVNIQKKVILIMSQVYKCVLQWMCSAKGVNDEKMYVWEMVKSMKIKLLEMADSENDGVRTHVVKFLEGMVMILSHSTSESEFPKNFKPESDINLSIVPEDSDNKYLKLKRLEDEGKNIFETMLHFQASPHISSINLMTVMGSITAIAKQRPAFFGKVVQAFESLQVNLPPTLAKSQVSSVRKNLKMHMLSLLRHRCSADYMTQITTLLTDLGATNSEVMKAMPKIDESK--KRKAEESTQVAKKAKIEEVELDDDDAGMTPFVDRTTTK-SAPTVKQQSTA------VDITSEDLESRLNAQ-NVADLVLISMVMLPDTMPAHFQSTYTPIAAAGTEGQIKHIARLLSTQLTTAGMGKGVAETQAQSEENEGAGGESPAYQPSSPKQLIQTVVGGLTDDLP----ALPSSSKAQSMQPPAPVRRGIKQFKLSSVTQELNRDDLDQMTISAVGRIL-----NAEKSATQGNV-------------LP----ARTKLLAGLTSQ-FGG-ELRDLLEEYIFEDLRSRFDLAFAWLYQEYANCMGFCAPLMKLEK----PSLAS---YDECLTRLLAGLLGRVDLKEGFFQRVLIEAPAVTDNAILILKKYCLDENRVVAGMSTLKELILTRPVHRHRFLNVMLESCSHDKPEVRSTAIRFTKK-LYEKPQIAPHIEEYASKMLKYLLLPKPPSEMFPRSRSGDLPQSWIEDIIKMCLYLYLGLLPSNHKLIQELAVVYTSATADIKRTILRVLENPVKGMGMQSPELLLLVENCPKGAETLVTRVIHILTDKAAPSQELVERVRDLYHKRVPDVRFLIPVLTGLHKREVILALPKLIKLNPVVVKEVFNRLLGGHG----ETSF---SSPLTPAELLISLHNIDPNKCDMKTIIKATNLCFSEKNVYTQEALAVVMKSLMEQAPLPTLFMRTVLQSLSMYPRLLGFVLNILQRLITKQVWKQKRVWEGFIKCCQRTKPQSFQVLLQLPSLQLKSVFESCPELREPLLNHVKSFTEHQITHIPKAIMAVLEKD 1093
BLAST of Symplekin vs. TrEMBL
Match: A0A433U5Q7 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_003086 PE=4 SV=1) HSP 1 Score: 669.848 bits (1727), Expect = 0.000e+0 Identity = 401/1107 (36.22%), Postives = 641/1107 (57.90%), Query Frame = 1
Query: 67 SIFDRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSLESKEKRETFQDESNSNS---ILEDFPMSGYANQKSKNQ-------MTLLKKHPFSTQ-KPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITSDVK--ETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLI 3348
S +D VV+L N + EK + + +ELI++K LLDNF +++L +++ +V+ ++ F+E ACK D + + K + + L+ D+ NV K++ + +++ L+L+ K K + A+ + + + + + ++S N G+ +K +E + + S+R DSE+PK E D S++++P + I + I LE+ G + F +++ H SS ++ T++ SL NIAKQRP+F +V++SFE HVN+P L + QV+S+RK LK ++ LL+H + L+F Q++TLL DLG +QSEI + PK D S+ ++ KE + K+AR ++ D Y D KK + K+ ++ ++++LP+LN NVTDLVLLSM+MLP MP F+S YTP+AAAGTQ QI+H++RLL+ QL A E +D+ +S I++ + G ++ Q M+ L P + K F L TK L E M+ + + + +RIL E C R +L +L S+LFG + + + L+ + + D++ R D+L + L +EY + + Y A + + ++ + AT+ Y L VL EL+ + ++ F R+LLEAPL+T A+ I+R YC+ + + G + + +L NNRP HR L I+LD+++ + E+R+ A+ AAK L S EEI +A L LL +KP + P L +P WT++ ++ LYL L L+P NH LIH LA V+ +KRTI+++++ P+K MGM+S E+L LVENC L++RVIHILTDKA+PSP +VE+++++YH + DVR +IP+L GL+KTE++E LPKL+ LN +V EVF RL+ + + SP+ P ELLVA+H ++ ++K I+A+ +CF EK +TQE L+IV+ QL++ LPTL MRT++QS SMYPR++G+V+N+L RLI K+VW+ +W+GFIRCC + QSF VLLQLP +L+ VF P+ R + ++ T+ QK H + A+++L+
Sbjct: 63 STYDTVVELLNQAAVMTKSAEKISSLRKAQELIIHKSSDLLDNFLDEMLAFQSDQSKDVKRFIVGFMEEACKKDFECLPKVMPSMVMLLGDDDVNVQKKVILTVSSMFRLTLAWISKAKQTRAEMKDVWVHLNELKNLMYDFLESINDGIRTHAVKFLEGLTLTLSKRTADSEVPKKNEEDFSVEQMPENNGI--VDIASLEEEGRKAFTTMLQFQGSPHISSINLMTVMNSLANIAKQRPEFFDQVVQSFEALHVNLPPTLAKSQVSSVRKNLKTQMMGLLRHSASLDFLPQISTLLTDLGASQSEIAKNTPK-DLESRKRKAFKEPSGFGPKKARIELDEDDDGM-TPYVDRTTKKSKPEPAQNKT-------AIDVTAEDILPRLN-AQNVTDLVLLSMVMLPNNMPALFESTYTPVAAAGTQAQISHIARLLATQLTMAAIA--------EGIKDDEQPSSPKQIIQ--TVVGLKTEEQTEQPPDKKLKMSQLPMPPGIRKIKQFQLSHATKPLQEEEMESMVNMALQRIL-----KAEKAACTGQVEQ-----------------HRTKLLAAL-SSLFGQS-VKKNLLAFILGDLRCRQDLLFAWLYQEYANCQGYSSAAAGGK---SSLQGATVGSYSNCLTSVLTELLEMEDHHADSLFHRVLLEAPLLTDNAVIIVRKYCNIPEHTEAGMKTLSQLINNRPAHRIRFLEIMLDYTAHEKQEIRNLAIQAAK-TLHVSGKMKEEIEQYANQQLKKLLLSKPPSP--PGVKLEDLPEAWTEDAIKAHLYLHLGLLPSNHKLIHELANVYTATNADIKRTILRVLEPPVKGMGMDSPELLTLVENCPKGSETLVMRVIHILTDKAVPSPQLVERIRDLYHKRVPDVRFLIPVLNGLSKTEVMEALPKLIKLNPMVVKEVFNRLMGSHV-----NNESMYQSPLTPVELLVALHNIDPNKCDIKTTIKAANLCFAEKATYTQEVLAIVMQQLMEQEPLPTLLMRTVLQSLSMYPRLLGFVLNILQRLIVKKVWRQKKVWEGFIRCCQRAKPQSFQVLLQLPASQLKDVFEVCPDLREPLFNHVQTFTENQKAHINKAVMTLL 1112
BLAST of Symplekin vs. TrEMBL
Match: V4AJ75 (Uncharacterized protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_215976 PE=4 SV=1) HSP 1 Score: 659.833 bits (1701), Expect = 0.000e+0 Identity = 409/1116 (36.65%), Postives = 649/1116 (58.15%), Query Frame = 1
Query: 127 EKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLT-YNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYL----SLESKEKRETFQDESNSN-----------------------SILEDFPMSGYANQKSKNQMT------LLKKHPFSTQK--PFNLESVTKTLPTETMQEIFHESFKRILVMPLL--NNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSD 3357
+K Y+ Q++ELI++K+P+LLDNF +++L + +R+ +V+ +I F+E ACK D +++ K++ + L+ D++ NV K++ ++ +I+ SL K K+ S++ ++ + + ++ ++S N G+ ++K +E +V++ S+R DS IPK E D++LD+IP T L++ LE+ G + F +L++ H SS ++ T++ +LTNIAKQRP F+ +V++ E HVN+P L + QV+S+RK LK +L+LLKHP+ ++ +Q+TTLL DLG +QSEI + +PK DE KRK ++ + +SK+A+ ++ D +T + IK+ APS+ Q+ + ++ ++++LPKLN+ NV DLVLLSM+MLP+TMP F+S YTPIAAAGT+ QIAHL+RLL+ QL AG+ L+ K E +D+ ++ + LED SG N+ S + T L P + +K F L ++T L + E+ + KR+L + NN + R IL +L +A FGG L L + +D+K R DI + L +EY + + +I + + ++ YD L +L L+ D ++ F R++LEAP++T A+ +LR Y + + G + +R+L RP+ R L ++L+F+ D EVR+ A+ K L+ + I +A NL LL KP + +WT+E ++ LYL+L L+P NHSLIH L+ V+ VKR I++M++ P+K MGM+S E+L +VENC L++RVIHILTDK+ PSP +VEK++++YH + DVR +IP+L GLTK E+ LPKL+ LN +V EVF RL+ V TSP+ P ELLVA+H ++ + ++K VI+A+ +CF EK I+T E L+I + QL+++ LPTL MRT++QS SMYPR++G+V+N+L RLI KQVWK +W+GFI+CC K QSF VLLQLP +L+ VF P+ R+ + ++ + T Q+ H S A+LS + +D
Sbjct: 6 DKIKYLRQVQELIIHKDPTLLDNFLDEMLAFISDRSVDVKKLLIGFLEEACKKDKEILPKALPGVTILLADDNANVKKKVILSLTSIFKYSLQWIAKAKTPSSEMTSVWENMMKTKKQVLELLESENDGIRTHVVKFLEGVVLVLSKRSTDSMIPKNMEGDITLDQIPESNTY--LKVNKLEEDGKKSFILLLQFQASPHISSINLMTVMGALTNIAKQRPIFLDQVVQGLEALHVNLPPTLAKSQVSSVRKNLKMQMLALLKHPASVDHLTQITTLLTDLGASQSEINKNMPKMDE--NRKRKLEQTSTSTSKKAKVEIDLDDDEVQMTPFVPQGIKR--APSVSQRQTA------IDITAEDILPKLNSQ-NVADLVLLSMVMLPDTMPAQFESTYTPIAAAGTEAQIAHLARLLATQLTMAGFGRGLGELQRKFLEEGVKDDGSTTPASPMDASYPSPKQLIQTLVGGTTNLED---SGTDNKPSSSSSTGVPGSFLQPSMPAAPRKLRQFKLSTITNPLDAGKIDEMTIATMKRVLTAETIAQNNNITSVRVK------------------------ILATL-TAQFGGG-LKDMLQTFIFEDLKTRSDIAFAWLYQEYANCQGFISVADPQTDKNS------LASYDECLTRLLSMLLDRPDQRDGLFSRLILEAPVVTDNAVEMLRRYSANESQTQNGMETLRKLILMRPNRRLHFLDVLLEFTGHDQPEVRNKAIEITK-TLLEKYQLNSPIETYALNNLKKLLLPKPLPEFFTGAKAKDVQEEWTEECIKMHLYLYLGLLPTNHSLIHELSNVYTATSADVKRAILRMLESPVKGMGMDSPELLTMVENCPKGAETLVMRVIHILTDKSAPSPELVEKIRDLYHKRVPDVRFLIPVLTGLTKKEVTGALPKLIKLNPVVVKEVFHRLMGGHG-----ESSVAYTSPLTPAELLVALHNIDPSKCDMKTVIKAANLCFSEKTIYTTEVLAIAMQQLMEINPLPTLLMRTVLQSLSMYPRLIGFVLNILHRLITKQVWKQQKVWEGFIKCCQKTKPQSFQVLLQLPPQQLQGVFEIAPDLRSPLYTHVQSLTPHQQAHISKAVLSTLEND 1067
BLAST of Symplekin vs. TrEMBL
Match: K9J0G0 (Putative mrna cleavage and polyadenylation factor ii complex subunit pta1 OS=Desmodus rotundus OX=9430 PE=2 SV=1) HSP 1 Score: 654.825 bits (1688), Expect = 0.000e+0 Identity = 400/1112 (35.97%), Postives = 629/1112 (56.56%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSS-KRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSL--ESKEKRETFQDE--SNSNSILEDFPMSGYANQKS-----KNQMTLLKKHPFSTQKPFNLESVT--KTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
+RVVDL N + ++ K + Q++ELI+ K+P+LLDNF ++I+ ++++ VR VI FIE ACK D +L+ K + L L+ DE+ NV+KR M +Y ++L +K + S E + C +V A+ + DS N G+ IK +E ++ S R DSE+P+ E+D+SLD++P D P +Q +L + G L+K + SS ++ T L SL NIA+QRP FMS VI+++E H N+P L + QV+S+RK LK LLS+LKHP+ LEF +Q+TTLL+DLG Q+EI R +P + RKR +++ SS K+ + N D D PS K+ + ++ E L L T NV +LVL+SM+ LPETMP +FQ+ YTP+ +AGT+ QI HL+RL++ Q+ +AG ++K+ +E ++E + S+L +S S + TL ++ P + ++P + VT + ++IF S ++ PL + +++ + + + +R IL SL + G L E++ + ++DV+ R D+ + L +EY +Y A + T+ Y+ L+ +L L D K+ F +++LEAPLIT AL ++R YC + G +R+L RP + + L ++LD SS + +VRS AL K + E E + FA L L+ P + + T + WTDE V+ CLYL+LAL+P NH LIH LA V+ +A +KRT++++I+ PI+ MGMNS E+L LVENC L+ R +H LTDK PSP +V++++++YH + DVR +IP+L GL K E+I+ LPKL+ LN +V EVF RLL G+ SP+ P ELL+A+H ++ + ++K +I+A+ +CF E+ ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+LSRLI KQVWK +W+GFI+CC + QSF V+LQLP +L +VF+ PE R + ++ + T Q+ H N+I++++ +
Sbjct: 34 ERVVDLLNQAA-LITSDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQVDKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKRAILTMTQLYKVALQWMVKSRVIS----ELQEACWDMVSAMAGDIILMLDSDNDGVRTHAIKFVEAFIVTLSPRMADSEVPRRHEHDVSLDRVPRDH--PYIQYNVLWEEGKAALEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPNNKDA----RKRPRDDSDSSLKKMKLEPNLGEDDEDKDLE-------PGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPETMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQSKEEPKEEKVAKPESVLIKRRLSAQGQAISVVGSLSSMSTLEEEAPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSD---VLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQQARVKILASLVTQFDSG--LKAEVLAFVLEDVRARLDLAFAWLYQEYNAYLAAGAS-------------GTLDKYEDCLIRLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVIRKYCEDESRTYLGMSTLRDLIFKRPSRQFQYLHVLLDLSSHEKDKVRSQALLFIKR-MYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTDETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HGEGNSALSPLNPGELLIALHNIDSSKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMTILEASG 1103
BLAST of Symplekin vs. Ensembl Cavefish
Match: sympk (symplekin [Source:ZFIN;Acc:ZDB-GENE-060526-361]) HSP 1 Score: 533.872 bits (1374), Expect = 1.671e-168 Identity = 358/1073 (33.36%), Postives = 583/1073 (54.33%), Query Frame = 1
Query: 178 PSLLDNFYE-DILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLS--LESKEKRETFQDESNSNSILEDFPMSGYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVK--------NRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELIT-SDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
P L + +E ++ +++ VR VI FIE ACK D++L+ K + L L++DES NV+K+ + +Y +SL ++ KS S + + E +++ +DS N G+ IK E ++I S R PDS++PK +E D+SLDKIP D + ++ ++L + G L+K + SS ++ T L SL +A+QRP FMS V++++E H N+P L + QV+S+RK LK L+S+L+HPS ++FHSQ++TLL DLGM QSEI R +P A +Q +++ + E KR + D D K+ AP + K + L+ + + L T NV +LVL+SM+ LPE MP +FQ+ YTP+ +AGT QI HL+RL+ A ++A L LE + R E + +E+ SK+ + + K S + ++ K+ P E + + L P+L + + +A ++ F + + S+ LT++ AE + + + M V+ + D+ SLL +EY Y + + + ++ Y+ L +L L + ++ F +++LEAPLIT AL ++R + L+ + S D +VRS AL+ K + ++ E I FA + L+ P + + + T + WT+E VR CLYL+L+L+P+NH L+H LA V+ +A +KR+++++I+ PI+ MGMNS ++L LVENC L+ R +HILTDK PSP +VE+++++YH + DVR +IP++ GL K E+I+ LPKL+ LN +V EVF RLL + SP+ P ELL+A+H ++ ++K +I+A+ +CF EK ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+LSRLI KQVWK +W+GF++CC + QS++VLLQLP +L SVF PE R + +++ + T Q+ H ++I++++ + S
Sbjct: 76 PFLHNQMFELHMIAFQTDKSIEVRKFVIGFIEEACKRDNELLLKLIANLNMLLKDESVNVVKKAILTLTHLYKVSLQWLVQSKSVSEMQEACWNMVTQMKEEVLALLDSDNDGVRTHAIKFTESLIIALSPRKPDSDVPKKQEGDISLDKIPKDHSY--IRYDVLCEEGKSALEQLLKFMVHPAISSINLTTALGSLATLARQRPMFMSEVVQAYETLHANLPPTLAKSQVSSVRKNLKLHLVSVLRHPSSVDFHSQISTLLQDLGMAQSEIARCVPAA---AQPRKRSRHEPYSEGKRIKIEPALIEDDED--------KEEPAPVVAPKPSTTTGTQSAIDLTADFIRPLLTPENVANLVLISMVYLPEVMPASFQATYTPVESAGTDAQIKHLARLM-ATQMTAAGLGPGLEQCKARGEEGKEGEGEASMEE--------SSSKDPLIIRKVSAVSLGQAISVVGAYKSQPAEETPQ------AKKLPEPILPS--TQSKAPGSSGRKKVFRLADVVQPLSDSQLEKLTNMAVKRILQAE--KAIARSGMSHVRVKLLARLMTQSDLAFSLLYQEYNQYLSQLPS-------------GSLDSYEHCLFSLLSGLQERPEQRDGLFTKLVLEAPLITESALEVIR---------------------------RTFLLQTCEHYSHDKEKVRSTALTFIKR-MYEKDHLREYIEKFALNYMQLLVHPNPPSLLFGVGEDTEVASPWTEETVRQCLYLYLSLLPLNHRLVHELAAVYTEAIADIKRSVLRVIEQPIRGMGMNSPDLLLLVENCPKGAETLVTRCLHILTDKVPPSPDLVERVRDLYHKRVPDVRFLIPVINGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HSEGSPSMSPLTPGELLIALHNIDSTKCDMKSIIKATNLCFGEKNVYTSEVLAVVMQQLMEQNPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLILKQVWKYPKVWEGFVKCCQRTKPQSYSVLLQLPPAQLISVFERCPEMREPLLQHVRSFTPHQQAHIPSSIMAILEASS 1070
BLAST of Symplekin vs. Ensembl Cavefish
Match: sympk (symplekin [Source:ZFIN;Acc:ZDB-GENE-060526-361]) HSP 1 Score: 371.318 bits (952), Expect = 1.309e-108 Identity = 195/518 (37.64%), Postives = 319/518 (61.58%), Query Frame = 1
Query: 1810 LVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDS 3360
++++ ++D++ R D+ SLL +EY Y + + + ++ Y+ L +L L + ++ F +++LEAPLIT AL ++R YC + G ++EL RP + + L ++LD SS D +VRS AL+ K + ++ E I FA + L+ P + + + T + WT+E VR CLYL+L+L+P+NH L+H LA V+ +A +KR+++++I+ PI+ MGMNS ++L LVENC L+ R +HILTDK PSP +VE+++++YH + DVR +IP++ GL K E+I+ LPKL+ LN +V EVF RLL + SP+ P ELL+A+H ++ ++K +I+A+ +CF EK ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+LSRLI KQVWK +W+GF++CC + QS++VLLQLP +L SVF PE R + +++ + T Q+ H ++I++++ + S
Sbjct: 618 MLRFILEDMRTRSDLAFSLLYQEYNQYLSQLPS-------------GSLDSYEHCLFSLLSGLQERPEQRDGLFTKLVLEAPLITESALEVIRRYCEDESRVYLGMTTLKELILKRPSRQFQYLHVLLDLSSHDKEKVRSTALTFIKR-MYEKDHLREYIEKFALNYMQLLVHPNPPSLLFGVGEDTEVASPWTEETVRQCLYLYLSLLPLNHRLVHELAAVYTEAIADIKRSVLRVIEQPIRGMGMNSPDLLLLVENCPKGAETLVTRCLHILTDKVPPSPDLVERVRDLYHKRVPDVRFLIPVINGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HSEGSPSMSPLTPGELLIALHNIDSTKCDMKSIIKATNLCFGEKNVYTSEVLAVVMQQLMEQNPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLILKQVWKYPKVWEGFVKCCQRTKPQSYSVLLQLPPAQLISVFERCPEMREPLLQHVRSFTPHQQAHIPSSIMAILEASS 1116 HSP 2 Score: 275.789 bits (704), Expect = 9.301e-76 Identity = 166/441 (37.64%), Postives = 261/441 (59.18%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAG 1398
++VVDL N + ++K + Q++ELI+ K+PSLLDNF ++++ +++ VR VI FIE ACK D++L+ K + L L++DES NV+K+ + +Y +SL ++ KS S + + E +++ +DS N G+ IK E ++I S R PDS++PK +E D+SLDKIP D + ++ ++L + G L+K + SS ++ T L SL +A+QRP FMS V++++E H N+P L + QV+S+RK LK L+S+L+HPS ++FHSQ++TLL DLGM QSEI R +P A +Q +++ + E KR + D D K+ AP + K + L+ + + L T NV +LVL+SM+ LPE MP +FQ+ YTP+ +AGT QI HL+RL++ Q+ +AG
Sbjct: 53 EKVVDLLNQAA-FMSTDDKLTALKQVQELIINKDPSLLDNFLDEMIAFQTDKSIEVRKFVIGFIEEACKRDNELLLKLIANLNMLLKDESVNVVKKAILTLTHLYKVSLQWLVQSKSVSEMQEACWNMVTQMKEEVLALLDSDNDGVRTHAIKFTESLIIALSPRKPDSDVPKKQEGDISLDKIPKDHSY--IRYDVLCEEGKSALEQLLKFMVHPAISSINLTTALGSLATLARQRPMFMSEVVQAYETLHANLPPTLAKSQVSSVRKNLKLHLVSVLRHPSSVDFHSQISTLLQDLGMAQSEIARCVPAA---AQPRKRSRHEPYSEGKRIKIEPALIEDDED--------KEEPAPVVAPKPSTTTGTQSAIDLTADFIRPLLTPENVANLVLISMVYLPEVMPASFQATYTPVESAGTDAQIKHLARLMATQMTAAG 479
BLAST of Symplekin vs. Ensembl Sea Lamprey
Match: sympk (symplekin [Source:ZFIN;Acc:ZDB-GENE-060526-361]) HSP 1 Score: 387.111 bits (993), Expect = 2.905e-116 Identity = 221/608 (36.35%), Postives = 341/608 (56.09%), Query Frame = 1
Query: 1534 HPFSTQKPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELI-TSDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPV--DWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLI 3348
P +K F + V + L +E M+ + H + RIL + R A RN +L L +A FGG E+ +L++ + D++ + D+ + L +EY +Y + + + + +YD L G+L L+ D ++ F R++LEAP +T AL +LR YC + G +REL RP + + ++L+ S D +VRS AL K L E I FA L L+ P + T V WTD+ +R CLY++L+L+P+NH+LIH LA V+ +A +KRTI+++I+ PI+ MGMNS E+L LVE+C L+ R +HILT+KA PSP +V++++++Y + SDVR +IP+L GL K E+I LPKL+ LN +V EVF RLL G+ V SP+ P ELLVA+H ++ ++K +I+A+ +CF E+ +++ E L++V+ QL++ LP L MRT++QS SMYPRM +V+N+L RLI KQVWK +W+GFI+CC + QSF VLLQLP +L VF+ PE R + ++ + T Q+ H S + ++++
Sbjct: 477 QPGIRRKVFRVADVLQPLSSEEMERMSHAAVGRILQA---DRTCMRGGAG-------------------HVRNQLLARL-AARFGG-EMRAQLLECVLADMRTQGDLAFTWLFQEYATY-------------LESEQPSALENYDNCLTGLLSGLLEKGDQRDGLFSRIVLEAPRMTGRALEVLRRYCEDETRVYLGMSTLRELVLKRPSQKMLYMHVLLELCSHDKDKVRSQALMFVKR-LYEKEELRNCIETFALNMLQCLVHPNPPSVCFADDRDTDAEVASSWTDDSIRQCLYVYLSLLPLNHTLIHELAAVYTEAIADIKRTILRIIEQPIRGMGMNSPELLLLVESCPKGAETLVTRSLHILTEKAPPSPELVKRVRDLYQKRVSDVRFLIPVLNGLEKKEVIAALPKLIKLNPIVVKEVFNRLLGTQ-----HGEGGVAMSPLTPGELLVALHNIDTTKCDMKSIIKATSLCFAERWVYSSEVLAVVMQQLMEQNPLPVLLMRTVIQSLSMYPRMGAFVMNILQRLIIKQVWKYPKVWEGFIKCCQRTKPQSFGVLLQLPPTQLAVVFDKCPEIREPLLMHVRSLTLQQQNHISKSTIAVL 1041 HSP 2 Score: 199.904 bits (507), Expect = 1.586e-52 Identity = 135/391 (34.53%), Postives = 220/391 (56.27%), Query Frame = 1
Query: 226 ERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAG 1398
+R +R +I F+E ACK D++L+ K + + L+ DE+ NV+KR ++ +Y + L + S + ++ + ++ +DS N G+ IK +E +V+ S R DSE+ K +E + +++IP D P L+ L + G L+ + SS ++ L SL IA+QRP FM+RV++++E H N+P L + QV+S+RK LK LL LLK PS +EFH Q++TLL DLG + E+ R +P A E+ +R +++ SK+ + V D D D + AP + +P + ++ ++ +LP L T V +LVL+SM++LP+TMP +FQ+ YTPI +AGT QI HL+RL++ Q+ +AG
Sbjct: 8 DRLLEIRKFIIGFMEEACKKDNELLLKLIANINMLLHDENVNVVKRAILSLTQLYRVMLQWLAGHRKVSEEQEAVWEMMSAMRNDIMQLLDSENDGVRTHAIKFVEMLVVAMSPRTQDSEVTKRQEGEACMERIPRDH--PLLKQSQLREMGEAALERLLSFMVHPAISSINLTAALGSLATIARQRPVFMARVVQAYETLHANLPPTLAKSQVSSVRKNLKLHLLGLLKLPSSIEFHPQMSTLLYDLGTSPQELQRNMPSARELR--RRMHRDDTEQHSKKMKM-VETMQDEDD----DKEAEAVPAPR-PKAAPLPSVLSAIDVTAQHILPML-TPDKVANLVLVSMVLLPDTMPASFQATYTPIESAGTHAQIQHLARLMATQISNAG 387
BLAST of Symplekin vs. Ensembl Nematostella
Match: EDO46859 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP74]) HSP 1 Score: 254.218 bits (648), Expect = 1.239e-76 Identity = 124/281 (44.13%), Postives = 189/281 (67.26%), Query Frame = 1
Query: 2539 MGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDSVVTVQTA 3381
+GM S E+L+LVENC + LI R+++I+TDKA PS +V ++K++YH + SDVR +IP+L GL K E+I +LPKL+ + +V EVF RLL V G TSP+ P ELLVA+H +E ++K V++A +CF EK I+TQE L+IV+ QL+++ LPTLFMRT++QS S+ PR++G+V+++L++LI KQVWK +W GF++CC QSF+VLLQLP +LES F PE R + ++ + T Q+ H ++L +++ + + + +
Sbjct: 1 IGMASPELLQLVENCPTGAETLIARILNIITDKAAPSSDLVRRVKDLYHKRVSDVRFLIPVLTGLEKQEIIAVLPKLIKQSPSVVKEVFNRLLGCFHSSKVSG-----TSPLSPSELLVALHSIE-GKSDMKAVMKAISLCFAEKAIYTQEVLAIVLQQLMEINPLPTLFMRTVIQSLSICPRLIGFVMSILAKLITKQVWKQPKVWQGFVKCCQMTKPQSFSVLLQLPPRQLESAFEICPELRDNLVAHVQSFTPHQRAHIPRSVLLILDKEKKIKTEKS 275
BLAST of Symplekin vs. Ensembl Nematostella
Match: EDO33007 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STE5]) HSP 1 Score: 222.631 bits (566), Expect = 1.294e-63 Identity = 159/439 (36.22%), Postives = 251/439 (57.18%), Query Frame = 1
Query: 79 RVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSA 1395
+V+DL N ++ E K + Q++E IV K+PSLLDNF +++L +R+A VR V+ FIE ACK D +L+ K + L + D++ V KR+ + +Y +L K + S + + ++ + +I + S N G+ IK ME +V++QS + DSE K E D+SLD +P P ++++ L + G L+ L+ SS ++ L +L+NIA+QRP FMS V+++FE H N+P L + QV+S+RK LK L+SLL+HPS EF Q+TTLL DLG +Q+E+ + +PKA S +K K + + ++K+A+ L ND I ++ ++ + +L+P+L+ VT+LVL+SM+ LP+ MP F YTPIAAAG Q Q+AHL+RLL++Q+ +A
Sbjct: 1 QVIDLLNQA--QLEKEGKLNCLKQVQEFIVNKDPSLLDNFLDEMLVFQQDRSAEVRKFVVGFIEEACKKDIELLGKVLSSLAVALGDDNVAVQKRVMLCVTQLYKFALQHVCKKRVISEELEQMWELLTQMKNQIIGMLASDNDGIRTHAIKFMEMLVLVQSTKSQDSESSKKGEADISLDVVPR--AHPLVKMQELREEGGTTLEALLSLIASPTISSVNLMAGLGTLSNIARQRPVFMSTVVQTFESLHANLPTSLSKSQVSSVRKNLKLHLMSLLRHPSSFEFLPQITTLLTDLGASQAELEKNMPKATPES-LKLKAESDTAAANKKAK-----------LLDNDDI-----------DMITMSNAEAIDLTANDLIPRLDKEA-VTNLVLISMLTLPDRMPSHFNDTYTPIAAAGGQAQVAHLARLLASQMTTA 411
BLAST of Symplekin vs. Ensembl Medaka
Match: sympk (symplekin [Source:NCBI gene;Acc:101158983]) HSP 1 Score: 592.808 bits (1527), Expect = 0.000e+0 Identity = 374/1113 (33.60%), Postives = 625/1113 (56.15%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKR-KEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYL-SLESKE-------KRETFQDESNSNSILEDFPMSGYANQKSKNQMTLLKKHPFSTQKPFNL----ESVTKTLPTETMQEIFHESFKRI--LVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINS 3354
++VV+L N + +EK + Q++ELI+ K+PSLLDNF ++I+ +++ V+ VI FIE ACK D++L+ + + L L++DES NV+K+ + +Y ++L + K+ S E + C ++ + +V DS N G+ IK E ++I S R PDS++PK ++ D+SLDK+P D + + L + G L+K + SS ++ T L SL IA+QRP FMS V++++E H N+P L + QV+S+RK LK L+++LKHP +EF Q++TLL+DLGM Q+EI R P V + RKR + E K+ + D D K+ AP K ++ L+ E L L T NV +LVL+SM+ LP+ MP +FQ+ YTP+ +AGT QI HL+R+++ Q+ +AG LE + K E +++S + IL + ++ + + + P +T+ P E + + PT+ M + R+ +V PL + + ++ ++ + + + R +L+ L + G + +++++ ++D+++R D+ SLL +EY +Y + + + + YD L +L L + ++ F +++LEAP+IT AL ++R YC + G ++EL RP + + L ++LD SS + +VR+ AL+ K + + + I FA L L+ P + + T + WT+E VR CL+L+L+L+P+NH L+H LA V+ +A +KR++++ I+ PI+ MGMNS E+L LVENC L+ R +HILTDK PSP +VE+++++YH + DVR +IP++ GL K E+I+ LPKL+ LN +V EVF RLL + SP+ P +LL+A+H ++ ++K +I+A+ +CF E+ ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+LSRLI KQVWK +W+GF++CC + QS++VLLQLP +L SVF PE R + +++ + T Q+ H ++I++++ +
Sbjct: 20 EKVVELLNQA-SLIPTDEKLTALKQVQELIINKDPSLLDNFLDEIIAFQTDKSIEVKKFVIGFIEEACKRDNELLVRLIANLNMLLKDESVNVVKKAILTLTQLYKVTLQWLVSSKTLS----EMQEACWDLITQMKGEVLALLDSDNDGVRTHSIKFTESLIITLSPRTPDSDVPKRQDADISLDKVPKDHSY--IHYGTLCEEGKSALEKLLKFMVHPAISSINLTTALGSLATIARQRPMFMSEVVQAYETLHANLPPTLAKSQVSSVRKNLKLHLVAVLKHPCSVEFQGQISTLLLDLGMPQTEITRNTP----VPREPRKRPRYEQYTEGKKVKIEPALMEDDED--------KEEPAPLAAPKPAAVPAVQSALDLTAEFLHPLLTPENVANLVLISMVYLPDVMPASFQATYTPVESAGTDAQIKHLARMMATQMTAAGIGPGLEQSKAKGDEACKEEQSEEDSTAKDILIKRKVPAVILGQAISVVGGYSEKPSATEPPAAPKRLPEPILPSAPTKLMGASGRKKVFRLSDVVQPLSDTQNEKLTSSAVKRILHSEKAIAQSGMSHI-RVKLLSRLVTQFEGM--MKEDVLQFILEDIRSRSDLAFSLLYQEYNTYLSQLPS-------------GLLDSYDQCLFTLLSGLQEKPEQRDGLFTKLVLEAPIITESALEVIRRYCEDESRVYLGMTTLKELIVKRPSRQFQYLHVLLDLSSNEKEKVRTTALAFLKR-MYEKDQLRDYIEKFALNYLQLLVHPNPPSLLFGADKDTEVAAPWTEETVRQCLFLYLSLLPLNHRLVHELASVYTEAIADIKRSVLRAIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHILTDKVPPSPELVERVRDLYHKRVPDVRFLIPVINGLEKNEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HSEGSSSVSPLTPGDLLIALHNIDSVKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQNPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLIVKQVWKYPKVWEGFVKCCQRTKPQSYSVLLQLPPAQLASVFERCPEMRAPLLQHVHSFTPHQQAHIPSSIMAVLEA 1091
BLAST of Symplekin vs. Ensembl Medaka
Match: sympk (symplekin [Source:NCBI gene;Acc:101158983]) HSP 1 Score: 561.992 bits (1447), Expect = 1.341e-179 Identity = 355/1077 (32.96%), Postives = 597/1077 (55.43%), Query Frame = 1
Query: 184 LLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKR-KEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYL-SLESKE-------KRETFQDESNSNSILEDFPMSGYANQKSKNQMTLLKKHPFSTQKPFNL----ESVTKTLPTETMQEIFHESFKRI--LVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINS 3354
L ++ ++I+ +++ V+ VI FIE ACK D++L+ + + L L++DES NV+K+ + +Y ++L + K+ S E + C ++ + +V DS N G+ IK E ++I S R PDS++PK ++ D+SLDK+P D + + L + G L+K + SS ++ T L SL IA+QRP FMS V++++E H N+P L + QV+S+RK LK L+++LKHP +EF Q++TLL+DLGM Q+EI R P V + RKR + E K+ + D D + A +S L+ E L L T NV +LVL+SM+ LP+ MP +FQ+ YTP+ +AGT QI HL+R+++ Q+ +AG LE + K E +++S + IL + ++ + + + P +T+ P E + + PT+ M + R+ +V PL + + ++ ++ + + + R +L+ L + G + +++++ ++D+++R D+ SLL +EY +Y + + + + YD L +L L + ++ F +++LEAP+IT AL ++R YC + G ++EL RP + + L ++LD SS + +VR+ AL+ K + + + I FA L L+ P + + T + WT+E VR CL+L+L+L+P+NH L+H LA V+ +A +KR++++ I+ PI+ MGMNS E+L LVENC L+ R +HILTDK PSP +VE+++++YH + DVR +IP++ GL K E+I+ LPKL+ LN +V EVF RLL + SP+ P +LL+A+H ++ ++K +I+A+ +CF E+ ++T E L++V+ QL++ LP L MRT++QS +MYPR+ G+V+N+LSRLI KQVWK +W+GF++CC + QS++VLLQLP +L SVF PE R + +++ + T Q+ H ++I++++ +
Sbjct: 5 LANSILQEIIAFQTDKSIEVKKFVIGFIEEACKRDNELLVRLIANLNMLLKDESVNVVKKAILTLTQLYKVTLQWLVSSKTLS----EMQEACWDLITQMKGEVLALLDSDNDGVRTHSIKFTESLIITLSPRTPDSDVPKRQDADISLDKVPKDHSY--IHYGTLCEEGKSALEKLLKFMVHPAISSINLTTALGSLATIARQRPMFMSEVVQAYETLHANLPPTLAKSQVSSVRKNLKLHLVAVLKHPCSVEFQGQISTLLLDLGMPQTEITRNTP----VPREPRKRPRYEQYTEGKKVKIEPALMEDDEDKEEPAPLAAPKPAAVPAVQS--------ALDLTAEFLHPLLTPENVANLVLISMVYLPDVMPASFQATYTPVESAGTDAQIKHLARMMATQMTAAGIGPGLEQSKAKGDEACKEEQSEEDSTAKDILIKRKVPAVILGQAISVVGGYSEKPSATEPPAAPKRLPEPILPSAPTKLMGASGRKKVFRLSDVVQPLSDTQNEKLTSSAVKRILHSEKAIAQSGMSHI-RVKLLSRLVTQFEGM--MKEDVLQFILEDIRSRSDLAFSLLYQEYNTYLSQLPS-------------GLLDSYDQCLFTLLSGLQEKPEQRDGLFTKLVLEAPIITESALEVIRRYCEDESRVYLGMTTLKELIVKRPSRQFQYLHVLLDLSSNEKEKVRTTALAFLKR-MYEKDQLRDYIEKFALNYLQLLVHPNPPSLLFGADKDTEVAAPWTEETVRQCLFLYLSLLPLNHRLVHELASVYTEAIADIKRSVLRAIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHILTDKVPPSPELVERVRDLYHKRVPDVRFLIPVINGLEKNEVIQALPKLIKLNPIVVKEVFNRLLGTQ-----HSEGSSSVSPLTPGDLLIALHNIDSVKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQNPLPMLLMRTVIQSLTMYPRLGGFVMNILSRLIVKQVWKYPKVWEGFVKCCQRTKPQSYSVLLQLPPAQLASVFERCPEMRAPLLQHVHSFTPHQQAHIPSSIMAVLEA 1041
BLAST of Symplekin vs. Ensembl Medaka
Match: sympk (symplekin [Source:NCBI gene;Acc:101158983]) HSP 1 Score: 458.373 bits (1178), Expect = 1.500e-142 Identity = 320/973 (32.89%), Postives = 530/973 (54.47%), Query Frame = 1
Query: 76 DRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKV----DSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKR-KEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSLESKE---KRETFQDESNSNSILEDFPMSGYANQKSKNQMTLLKKHPFSTQKPFN----LESVTKTLPTETMQEIFHESFKRI--LVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITS-DVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEA 2949
++VV+L N + +EK + Q++ELI+ K+PSLLDNF ++I+ +++ V+ VI FIE ACK D++L+ + + L L++DES NV+K+ + +Y ++L + K+ S E + C ++ + +V DS N G+ IK E ++I S R PDS++PK ++ D+SLDK+P D + + L + G L+K + SS ++ T L SL IA+QRP FMS V++++E H N+P L + QV+S+RK LK L+++LKHP +EF Q++TLL+DLGM Q+EI R P V + RKR + E K+ + D D K+ AP K ++ L+ E L L T NV +LVL+SM+ LP+ MP +FQ+ YTP+ +AGT QI HL+R+++ Q+ +AG E + K E +++S + IL + ++ + + + P +T+ P E + + PT+ M + R+ +V PL + + ++ T+++V + + S L S F G + +++++ ++D+++R D+ SLL +EY +Y + + + + YD L +L L + ++ F +++LEAP+IT AL ++R YC + G ++EL RP + + L ++LD SS + +VR+ AL+ K + + + I FA L L+ P + + T + WT+E VR CL+L+L+L+P+NH L+H LA V+ +A +KR++++ I+ PI+ MGMNS E+L LVENC L+ R +HILTDK PSP +VE+++++YH + DVR +IP++ GL K E+I+ LPKL+ LN +V EVF RLL + G V SP+ P +LL+A+H ++ ++K +I+A
Sbjct: 20 EKVVELLNQA-SLIPTDEKLTALKQVQELIINKDPSLLDNFLDEIIAFQTDKSIEVKKFVIGFIEEACKRDNELLVRLIANLNMLLKDESVNVVKKAILTLTQLYKVTLQWLVSSKTLS----EMQEACWDLITQMKGEVLALLDSDNDGVRTHSIKFTESLIITLSPRTPDSDVPKRQDADISLDKVPKDHSY--IHYGTLCEEGKSALEKLLKFMVHPAISSINLTTALGSLATIARQRPMFMSEVVQAYETLHANLPPTLAKSQVSSVRKNLKLHLVAVLKHPCSVEFQGQISTLLLDLGMPQTEITRNTP----VPREPRKRPRYEQYTEGKKVKIEPALMEDDED--------KEEPAPLAAPKPAAVPAVQSALDLTAEFLHPLLTPENVANLVLISMVYLPDVMPASFQATYTPVESAGTDAQIKHLARMMATQMTAAGIGPGEHHKRACKEEQSEEDSTAKDILIKRKVPAVILGQAISVVGGYSEKPSATEPPAAPKRLPEPILPSAPTKLMGASGRKKVFRLSDVVQPLSDTQNEKL---TSSAVKRILHSEKAIAQSGMSHVIKLLSRLVTQFEGM-MKEDVLQFILEDIRSRSDLAFSLLYQEYNTYLSQLPS-------------GLLDSYDQCLFTLLSGLQEKPEQRDGLFTKLVLEAPIITESALEVIRRYCEDESRVYLGMTTLKELIVKRPSRQFQYLHVLLDLSSNEKEKVRTTALAFLKR-MYEKDQLRDYIEKFALNYLQLLVHPNPPSLLFGADKDTEVAAPWTEETVRQCLFLYLSLLPLNHRLVHELASVYTEAIADIKRSVLRAIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHILTDKVPPSPELVERVRDLYHKRVPDVRFLIPVINGLEKNEVIQALPKLIKLNPIVVKEVFNRLLGTQHSE---GSSSV--SPLTPGDLLIALHNIDSVKCDMKSIIKA 950
BLAST of Symplekin vs. Planmine SMEST
Match: SMESG000046152.1 (SMESG000046152.1) HSP 1 Score: 2358.56 bits (6111), Expect = 0.000e+0 Identity = 1203/1204 (99.92%), Postives = 1203/1204 (99.92%), Query Frame = 1
Query: 58 MPHSIFDRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKAXXXXXXXXXXHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSLESKEKRETFQDESNSNSILEDFPMSGYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTXXXXXXXXXXXXXMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITSDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDSVVTVQTATVENVVPNGNGAQNPANSDTVPIPNESITTETVVAFVTPKIEKFTSSSLAKAAMXXXXXXXXXXXXXXXXXXXXXGGNKISFFPLKPSDSSNKEAK 3669
MPHSIFDRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKALKGSLLSLLKHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSLESKEKRETFQDESNSNSILEDFPMSGYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTNNSVNSFFVDSSNMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITSDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDSVVTVQTATVENVVPNGN AQNPANSDTVPIPNESITTETVVAFVTPKIEKFTSSSLAKAAMDKEKLDEDRKKKEKAKQLLEKGGNKISFFPLKPSDSSNKEAK
Sbjct: 1 MPHSIFDRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDILGLLIERNANVRVTVIDFIENACKVDSDLVNKSVERLRFLIEDESFNVMKRLATAMMTIYPLSLSQAIKLKSSSADDIEAFQYCLVIVEALISKVDSPNGGMLLMLIKLMECIVILQSQRFPDSEIPKGKENDLSLDKIPADLTIPCLQIEILEKSGLRLFNVLIKLLNREHSSSSHIHTLLASLTNIAKQRPQFMSRVIESFELTHVNMPDKLGEIQVNSIRKALKGSLLSLLKHPSCLEFHSQVTTLLIDLGMTQSEIVRALPKADEVSQMKRKRKEENNLSSKRARTSVNAHSDYSDLTYNDSIIKKFAAPSLEQKSPSLRKPNYVEQLSKELLPKLNTVINVTDLVLLSMMMLPETMPPAFQSAYTPIAAAGTQTQIAHLSRLLSAQLVSAGYLSLESKEKRETFQDESNSNSILEDFPMSGYANQKSKNQMTLLKKHPFSTQKPFNLESVTKTLPTETMQEIFHESFKRILVMPLLNNELKRCRANTNNSVNSFFVDSSNMPKWYFSRNTILTSLPSALFGGAELYRELVKYCMKDVKNRYDILLSLLIKEYTSYKAYILAISKHRENTATPRLATISDYDAVLVGVLKELITSDVKETYFGRMLLEAPLITTGALNILRSYCSAKVNADYGFQIIRELFNNRPDHRKELLMIILDFSSEDNMEVRSAALSAAKWILMTSENFSEEILDFAKTNLNYLLQAKPSNSIHPLQHLTVMPVDWTDEVVRPCLYLFLALMPVNHSLIHLLAEVFVKACQIVKRTIIKMIDIPIKEMGMNSEEILRLVENCDSNQVVLIIRVIHILTDKAMPSPLMVEKLKNIYHNKYSDVRLIIPILKGLTKTEMIEILPKLVVLNDKLVSEVFRRLLDVSAFDPVKGDFVVKTSPILPEELLVAVHQLEFANVELKVVIEASKMCFREKQIFTQERLSIVIGQLLDLPVLPTLFMRTLMQSFSMYPRMVGYVVNVLSRLIKKQVWKNSSLWDGFIRCCVKLGQQSFAVLLQLPVDKLESVFNSVPEFRTQMRRYIDNCTQAQKLHFSNAILSLINSDSVVTVQTATVENVVPNGNSAQNPANSDTVPIPNESITTETVVAFVTPKIEKFTSSSLAKAAMDKEKLDEDRKKKEKAKQLLEKGGNKISFFPLKPSDSSNKEAK 1204 The following BLAST results are available for this feature:
BLAST of Symplekin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Symplekin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Symplekin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Symplekin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of Symplekin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Symplekin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of Symplekin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of Symplekin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Symplekin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Symplekin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Symplekin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Symplekin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Symplekin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 3
BLAST of Symplekin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30023927 ID=SMED30023927|Name=Symplekin|organism=Schmidtea mediterranea sexual|type=transcript|length=3753bpback to top protein sequence of SMED30023927-orf-1 >SMED30023927-orf-1 ID=SMED30023927-orf-1|Name=SMED30023927-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1205bp MPHSIFDRVVDLCNSTIETVDAEEKALYINQIKELIVYKEPSLLDNFYEDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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