PDZ domain-containing protein

Overview


Name	PDZ domain-containing protein
Smed ID	SMED30023885
Length (bp)	1647

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of PDZ domain-containing protein (SMED30023885) t-SNE clustered cells

Violin plots show distribution of expression levels for PDZ domain-containing protein (SMED30023885) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PDZ domain-containing protein (SMED30023885) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PDZ domain-containing protein (SMED30023885) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30023885

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
cephalic ganglia	SMED30023885	SMESG000012918.1	dd_Smed_v4_11887_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
anterior side	SMED30023885	SMESG000012918.1	dd_Smed_v4_11887_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30023885	SMESG000012918.1	dd_Smed_v4_11887_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30023885	SMESG000012918.1	Contig49165	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30023885	SMESG000012918.1	Contig49165	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
enteric muscle cell	SMED30023885	SMESG000012918.1	dd_Smed_v4_11887_0_1	dd_Smed_v4	PMID:30471994 Scimone et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: SYNPO2L (synaptopodin 2 like [Source:HGNC Symbol;Acc:HGNC:23532])

HSP 1 Score: 60.8474 bits (146), Expect = 5.400e-9
Identity = 32/78 (41.03%), Postives = 47/78 (60.26%), Query Frame = 1

Query:  304 IILRDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGR 531
            + L  G PWGFR++   ++ + L V +IR+ S A  A L+E D + AIN  S   LSH+ A+ LID +  +L+L V R
Sbjct:    9 VTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHASAMSLIDASGNQLVLTVQR 86

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: PDLIM3 (PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:20767])

HSP 1 Score: 53.9138 bits (128), Expect = 3.623e-8
Identity = 31/81 (38.27%), Postives = 44/81 (54.32%), Query Frame = 1

Query:  304 IILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            +IL    PWGFR+    D N+ L++ RI   S A  A L  GDVI AI+ F    ++H+DA + I     +L L + R E+
Sbjct:    1 VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGET 81

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: PDLIM3 (PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:20767])

HSP 1 Score: 55.4546 bits (132), Expect = 8.065e-8
Identity = 31/83 (37.35%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + +IL    PWGFR+    D N+ L++ RI   S A  A L  GDVI AI+ F    ++H+DA + I     +L L + R E+
Sbjct:    3 QTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: PDLIM3 (PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:20767])

HSP 1 Score: 56.225 bits (134), Expect = 8.489e-8
Identity = 31/83 (37.35%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + +IL    PWGFR+    D N+ L++ RI   S A  A L  GDVI AI+ F    ++H+DA + I     +L L + R E+
Sbjct:    3 QTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Human
Match: PDLIM3 (PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:20767])

HSP 1 Score: 55.4546 bits (132), Expect = 1.009e-7
Identity = 31/83 (37.35%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + +IL    PWGFR+    D N+ L++ RI   S A  A L  GDVI AI+ F    ++H+DA + I     +L L + R E+
Sbjct:    3 QTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: Zasp66 (gene:FBgn0035917 transcript:FBtr0089563)

HSP 1 Score: 57.7658 bits (138), Expect = 1.449e-8
Identity = 45/125 (36.00%), Postives = 62/125 (49.60%), Query Frame = 1

Query:  304 IILRDG--PPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQGTVQNNAVSKIFLNLTREPLTTPASPDLVP 666
            ++LRDG   PWG R+    D +  LI+ R++  SPA   +L  GD+IS I  + AR LSH+DA +L      E+ L+V R   +          QG  Q  A      N T  P+T    PDL+P
Sbjct:   11 VLLRDGQATPWGIRLVGGNDLDTPLIITRVQVGSPAH-GELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAYT-------QGATQ-EAGPGSRSNSTLPPVT----PDLMP 122

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: Zasp66 (gene:FBgn0035917 transcript:FBtr0301154)

HSP 1 Score: 57.3806 bits (137), Expect = 1.478e-8
Identity = 45/125 (36.00%), Postives = 62/125 (49.60%), Query Frame = 1

Query:  304 IILRDG--PPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQGTVQNNAVSKIFLNLTREPLTTPASPDLVP 666
            ++LRDG   PWG R+    D +  LI+ R++  SPA   +L  GD+IS I  + AR LSH+DA +L      E+ L+V R   +          QG  Q  A      N T  P+T    PDL+P
Sbjct:   11 VLLRDGQATPWGIRLVGGNDLDTPLIITRVQVGSPAH-GELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAYT-------QGATQ-EAGPGSRSNSTLPPVT----PDLMP 122

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: Zasp66 (gene:FBgn0035917 transcript:FBtr0301156)

HSP 1 Score: 56.9954 bits (136), Expect = 1.845e-8
Identity = 45/125 (36.00%), Postives = 62/125 (49.60%), Query Frame = 1

Query:  304 IILRDG--PPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQGTVQNNAVSKIFLNLTREPLTTPASPDLVP 666
            ++LRDG   PWG R+    D +  LI+ R++  SPA   +L  GD+IS I  + AR LSH+DA +L      E+ L+V R   +          QG  Q  A      N T  P+T    PDL+P
Sbjct:   11 VLLRDGQATPWGIRLVGGNDLDTPLIITRVQVGSPAH-GELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAYT-------QGATQ-EAGPGSRSNSTLPPVT----PDLMP 122

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Match: Zasp66 (gene:FBgn0035917 transcript:FBtr0089568)

HSP 1 Score: 56.6102 bits (135), Expect = 2.064e-8
Identity = 45/125 (36.00%), Postives = 62/125 (49.60%), Query Frame = 1

Query:  304 IILRDG--PPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQGTVQNNAVSKIFLNLTREPLTTPASPDLVP 666
            ++LRDG   PWG R+    D +  LI+ R++  SPA   +L  GD+IS I  + AR LSH+DA +L      E+ L+V R   +          QG  Q  A      N T  P+T    PDL+P
Sbjct:   11 VLLRDGQATPWGIRLVGGNDLDTPLIITRVQVGSPAH-GELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAYT-------QGATQ-EAGPGSRSNSTLPPVT----PDLMP 122

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: synpo2la (synaptopodin 2-like a [Source:ZFIN;Acc:ZDB-GENE-090828-4])

HSP 1 Score: 56.6102 bits (135), Expect = 6.235e-8
Identity = 39/116 (33.62%), Postives = 56/116 (48.28%), Query Frame = 1

Query:  304 IILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQGTVQNNAVSKIFLNLTREPLTTP 645
            I L  G PWGFR+    +  + L V ++R+ S A  A L+EGD + +IN  S   LSH+ A+ LID     L + V R  S  +       HQ +V+      +     R  LT+P
Sbjct:    8 ITLSGGAPWGFRLQGGIEHQKPLQVAKVRKRSKACRAGLREGDELMSINENSCGSLSHAQAMNLIDSMPGTLHIRVRRAMSPSSSR----PHQSSVRQIHRGTLMSPTGRSGLTSP 119

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: pdlim3a (PDZ and LIM domain 3a [Source:ZFIN;Acc:ZDB-GENE-050505-1])

HSP 1 Score: 52.7582 bits (125), Expect = 4.358e-7
Identity = 36/89 (40.45%), Postives = 48/89 (53.93%), Query Frame = 1

Query:  283 MPFIQKEIILRDGP-PWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            MPF     ++ DGP PWGFR+    D ++ L V +I   S A T  L  GD+I +I+  SA  L HS+A  LI     +L L V R E+
Sbjct:    1 MPFT----VVLDGPAPWGFRLIGGRDFSQPLTVAKISPGSKASTVNLSPGDIILSIDGVSAENLMHSEAQTLIKDASYQLTLTVERPET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: synpo2la (synaptopodin 2-like a [Source:ZFIN;Acc:ZDB-GENE-090828-4])

HSP 1 Score: 53.9138 bits (128), Expect = 4.629e-7
Identity = 31/78 (39.74%), Postives = 43/78 (55.13%), Query Frame = 1

Query:  304 IILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGR 531
            I L  G PWGFR+    +  + L V ++R+ S A  A L+EGD + +IN  S   LSH+ A+ LID     L + V R
Sbjct:    8 ITLSGGAPWGFRLQGGIEHQKPLQVAKVRKRSKACRAGLREGDELMSINENSCGSLSHAQAMNLIDSMPGTLHIRVRR 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Match: pdlim3a (PDZ and LIM domain 3a [Source:ZFIN;Acc:ZDB-GENE-050505-1])

HSP 1 Score: 52.7582 bits (125), Expect = 4.810e-7
Identity = 36/89 (40.45%), Postives = 48/89 (53.93%), Query Frame = 1

Query:  283 MPFIQKEIILRDGP-PWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            MPF     ++ DGP PWGFR+    D ++ L V +I   S A T  L  GD+I +I+  SA  L HS+A  LI     +L L V R E+
Sbjct:    1 MPFT----VVLDGPAPWGFRLIGGRDFSQPLTVAKISPGSKASTVNLSPGDIILSIDGVSAENLMHSEAQTLIKDASYQLTLTVERPET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
Match: foxi4.2 (forkhead box I4, gene 2 [Source:Xenbase;Acc:XB-GENE-487658])

HSP 1 Score: 51.9878 bits (123), Expect = 1.025e-6
Identity = 29/83 (34.94%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + ++L    PWGFR+    D N+ LI+ RI   S +  A L  GDVI AI+ F    ++H++A + I     +L L + R E+
Sbjct:    3 QNVVLPGPAPWGFRLTGGIDFNQPLIISRITPGSKSSLANLCPGDVILAIDGFGTENMTHAEAQDRIKAATDQLCLKIERAET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
Match: foxi4.2 (forkhead box I4, gene 2 [Source:Xenbase;Acc:XB-GENE-487658])

HSP 1 Score: 52.373 bits (124), Expect = 1.163e-6
Identity = 29/83 (34.94%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + ++L    PWGFR+    D N+ LI+ RI   S +  A L  GDVI AI+ F    ++H++A + I     +L L + R E+
Sbjct:    3 QNVVLPGPAPWGFRLTGGIDFNQPLIISRITPGSKSSLANLCPGDVILAIDGFGTENMTHAEAQDRIKAATDQLCLKIERAET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
Match: foxi4.2 (forkhead box I4, gene 2 [Source:Xenbase;Acc:XB-GENE-487658])

HSP 1 Score: 51.9878 bits (123), Expect = 1.210e-6
Identity = 29/83 (34.94%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + ++L    PWGFR+    D N+ LI+ RI   S +  A L  GDVI AI+ F    ++H++A + I     +L L + R E+
Sbjct:    3 QNVVLPGPAPWGFRLTGGIDFNQPLIISRITPGSKSSLANLCPGDVILAIDGFGTENMTHAEAQDRIKAATDQLCLKIERAET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
Match: foxi4.2 (forkhead box I4, gene 2 [Source:Xenbase;Acc:XB-GENE-487658])

HSP 1 Score: 51.2174 bits (121), Expect = 1.451e-6
Identity = 29/83 (34.94%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + ++L    PWGFR+    D N+ LI+ RI   S +  A L  GDVI AI+ F    ++H++A + I     +L L + R E+
Sbjct:    3 QNVVLPGPAPWGFRLTGGIDFNQPLIISRITPGSKSSLANLCPGDVILAIDGFGTENMTHAEAQDRIKAATDQLCLKIERAET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Synpo2l (synaptopodin 2-like [Source:MGI Symbol;Acc:MGI:1916010])

HSP 1 Score: 58.9214 bits (141), Expect = 1.458e-8
Identity = 31/79 (39.24%), Postives = 47/79 (59.49%), Query Frame = 1

Query:  301 EIILRDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGR 531
            ++ L  G PWGFR+    ++ + L V +IR+ S A  A L+E D + AIN  S    SH+ A+ LID + ++L+L V R
Sbjct:    8 QVTLAGGAPWGFRLQGGTEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNFSHASAMTLIDASGRQLVLTVRR 86

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Pdlim3 (PDZ and LIM domain 3 [Source:MGI Symbol;Acc:MGI:1859274])

HSP 1 Score: 55.0694 bits (131), Expect = 1.153e-7
Identity = 30/83 (36.14%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + ++L    PWGFR+    D N+ L++ RI   S A  A L  GDVI AI+ F    ++H+DA + I     +L L + R E+
Sbjct:    3 QNVVLPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAASYQLCLKIDRAET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Pdlim3 (PDZ and LIM domain 3 [Source:MGI Symbol;Acc:MGI:1859274])

HSP 1 Score: 54.6842 bits (130), Expect = 1.394e-7
Identity = 30/83 (36.14%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + ++L    PWGFR+    D N+ L++ RI   S A  A L  GDVI AI+ F    ++H+DA + I     +L L + R E+
Sbjct:    3 QNVVLPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAASYQLCLKIDRAET 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Synpo2l (synaptopodin 2-like [Source:MGI Symbol;Acc:MGI:1916010])

HSP 1 Score: 53.5286 bits (127), Expect = 6.913e-7
Identity = 31/78 (39.74%), Postives = 45/78 (57.69%), Query Frame = 1

Query:  301 EIILRDGPPWGFRIYED-ENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGR 531
            ++ L  G PWGFR+    E R  +  +IR+ S A  A L+E D + AIN  S    SH+ A+ LID + ++L+L V R
Sbjct:    8 QVTLAGGAPWGFRLQGGTEQRKPL--QIRRRSQAGRAGLRERDQLLAINGVSCTNFSHASAMTLIDASGRQLVLTVRR 83

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Match: Pdlim4 (PDZ and LIM domain 4 [Source:MGI Symbol;Acc:MGI:1353470])

HSP 1 Score: 50.447 bits (119), Expect = 2.130e-6
Identity = 48/159 (30.19%), Postives = 65/159 (40.88%), Query Frame = 1

Query:  292 IQKEIILRDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFI--------------EHQ----GTVQNNAVSKIFLNLTREPLTTP-ASPDLVPVPISKLMKEYDIP 705
            +   + LR   PWGFR+    D +  L + R+   S A  A L  GD+I AIN  S   ++H +A   I      L L V R E   NKN                  E Q     T + ++VS I L   R  L +P   P  +PVP +    E  +P
Sbjct:    1 MTHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPE---NKNWPSAPDDKAQAHRIHIDPESQDCSPATSRRSSVSGISLEDNRSGLGSPYGQPPRLPVPHNGSSNEATLP 156

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9H987|SYP2L_HUMAN (Synaptopodin 2-like protein OS=Homo sapiens OX=9606 GN=SYNPO2L PE=1 SV=3)

HSP 1 Score: 60.8474 bits (146), Expect = 2.593e-8
Identity = 32/78 (41.03%), Postives = 47/78 (60.26%), Query Frame = 1

Query:  304 IILRDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGR 531
            + L  G PWGFR++   ++ + L V +IR+ S A  A L+E D + AIN  S   LSH+ A+ LID +  +L+L V R
Sbjct:    9 VTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHASAMSLIDASGNQLVLTVQR 86

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9PU47|PDLI3_CHICK (PDZ and LIM domain protein 3 OS=Gallus gallus OX=9031 GN=PDLIM3 PE=1 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 4.016e-8
Identity = 34/83 (40.96%), Postives = 46/83 (55.42%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + +IL    PWGFR+    D N+ LI+ RI   S A TA L  GD+I AIN  S   ++H+DA E I     +L L + R E+
Sbjct:    3 QNVILPGPAPWGFRLSGGIDFNQPLIITRITPGSKASTANLCPGDIIVAINGLSTENMTHNDAQERIKAAAHQLSLRIERAET 85

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q66HS7|PDLI3_RAT (PDZ and LIM domain protein 3 OS=Rattus norvegicus OX=10116 GN=Pdlim3 PE=1 SV=2)

HSP 1 Score: 56.225 bits (134), Expect = 3.905e-7
Identity = 30/83 (36.14%), Postives = 46/83 (55.42%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + ++L    PWGFR+    D N+ L++ RI   S A+ A L  GDVI AI+ F    ++H+DA + I     +L L + R E+
Sbjct:    3 QNVVLPGPAPWGFRLSGGIDFNQPLVITRITPGSKAEAANLCPGDVILAIDGFGTESMTHADAQDRIKAASYQLCLKIDRAET 85

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q53GG5|PDLI3_HUMAN (PDZ and LIM domain protein 3 OS=Homo sapiens OX=9606 GN=PDLIM3 PE=1 SV=1)

HSP 1 Score: 56.225 bits (134), Expect = 4.077e-7
Identity = 31/83 (37.35%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + +IL    PWGFR+    D N+ L++ RI   S A  A L  GDVI AI+ F    ++H+DA + I     +L L + R E+
Sbjct:    3 QTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGET 85

[Close]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6QGC0|PDLI3_PIG (PDZ and LIM domain protein 3 OS=Sus scrofa OX=9823 GN=PDLIM3 PE=2 SV=1)

HSP 1 Score: 55.8398 bits (133), Expect = 5.062e-7
Identity = 31/83 (37.35%), Postives = 45/83 (54.22%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIYE--DENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            + +IL    PWGFR+    D N+ LI+ RI   S A  A L  GDVI AI+ +    ++H+DA + I     +L L + R E+
Sbjct:    3 QNVILPGPAPWGFRLSGGIDFNQPLIITRITPGSKAAAANLCPGDVILAIDGYGTESMTHADAQDRIKAAAHQLCLKIDRAET 85

[Close]

BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A158QV81 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS7422 PE=4 SV=1)

HSP 1 Score: 217.238 bits (552), Expect = 3.514e-61
Identity = 137/376 (36.44%), Postives = 215/376 (57.18%), Query Frame = 1

Query:  283 MPFIQKEIILRDGPPWGFRIYEDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFI----EHQGTVQNNAVSKIFLNLT----------------REPLTTPASPDLVPVPISKLMKEYDIPPRPENAAKRKRFANSEFFNDPNTYYPTLEEKIEMAKNLAESLTAPVNCKSKGANIFERQRQRIEKYVKEGPDPEPEKELLQIILQDGSVRTLDXXXXXXXXXXXXXXXXXX-GLPTDINKKEIRLPPPPGAPKTLKEYLERIKKYPTVKHDAIGPEKCFTIASALHYGHDRGSNIFQKIRVRSKKWEISSETIKESPVVIFSSKSVNQQKPASKL 1347
            M  ++  I +R GPPWGFR+ +  N GLIV +IR+ SPA+ A L+E DV+ AIN  S R L+ + AI +I+    +L L+V R E    + +TF       +G +    ++   L++T                  P   PA P++ PV   +LMK+YD+P +   + K++ FANS F+   N +YP++EE+IEMA+ +A+S+ APVN  S+GA IFE Q+QR EKYVKEGP+P P+        ++ + + L+      PPP  +P       L + I       PPPPG P++++E++E+I+++P   H  I P+ CF IA+ALH    RG ++F K + +++ WEI +  +   PV + +++ V + K  SKL
Sbjct:    1 MQTVEHVIRMRQGPPWGFRLADTFNGGLIVSQIRRQSPAEMAGLRENDVVVAINNISTRGLNRTYAINIINNADYQLDLIVQRQERRKPQMMTFFLDTSAARGQLVRQEMASRDLDITWRKEPSPPPPPPPPPPEPPRIVPADPNVTPVSFDRLMKKYDVP-QAAPSFKKRTFANSAFYAGTNVFYPSVEEQIEMARRVAKSIEAPVNQGSRGAQIFEAQQQRAEKYVKEGPEPVPDP------FENATAQQLEYMIPPAPPPPPAPTAPSFPSLTSSIPPAPPPPPPPPGQPRSVQEFIEKIRRFPKNTHMEISPQVCFDIAAALHTSGSRGGSMFAKRKAKAQNWEIENTGV---PVPVLTAQHVEKPKLVSKL 366

[Close]

BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A5K3EX68 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 216.853 bits (551), Expect = 1.690e-60
Identity = 136/376 (36.17%), Postives = 214/376 (56.91%), Query Frame = 1

Query:  283 MPFIQKEIILRDGPPWGFRIYEDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFI----EHQGTVQNNAVSKIFLNLTREPLT----------------TPASPDLVPVPISKLMKEYDIPPRPENAAKRKRFANSEFFNDPNTYYPTLEEKIEMAKNLAESLTAPVNCKSKGANIFERQRQRIEKYVKEGPDPEPEKELLQIILQDGSVRTLDXXXXXXXXXXXXXXXXXX-GLPTDINKKEIRLPPPPGAPKTLKEYLERIKKYPTVKHDAIGPEKCFTIASALHYGHDRGSNIFQKIRVRSKKWEISSETIKESPVVIFSSKSVNQQKPASKL 1347
            M  ++  I +R GPPWGFR+ +  N GLIV +IR+ SPA+ A L+E DV+ AIN  S R L+ + AI +I+    +L L+V R E    + +TF       +G +    ++   L++T                      PA P++ PV   +LMK+YD+P +   + K++ FANS F+   N +YP++EE+IEMA+ +A+S+ APVN  S+GA IFE Q+QR EKYVKEGP+P P+        ++ + + L+      PPP  +P       L + I       PPPPG P++++E++E+I+++P   H  I P+ CF IA+ALH    RG ++F K + +++ WEI +  +   PV + +++ V + K  SKL
Sbjct:    1 MQTVEHVIRMRQGPPWGFRLADTFNGGLIVSQIRRQSPAEMAGLRENDVVVAINNISTRGLNRTYAINIINNADYQLDLIVQRQERRKPQMMTFFLDTSAARGQLVRQEMASRDLDITWRKEPSPPPPPPPPPPEPPRIVPADPNVTPVSFDRLMKKYDVP-QAAPSFKKRTFANSAFYAGTNVFYPSVEEQIEMARRVAKSIEAPVNQGSRGAQIFEAQQQRAEKYVKEGPEPVPDP------FENATAQQLEYMIPPAPPPPPAPTAPSFPSLTSSIPPAPPPPPPPPGQPRSVQEFIEKIRRFPKNTHMEISPQVCFDIAAALHTSGSRGGSMFAKRKAKAQNWEIENTGV---PVPVLTAQHVEKPKLVSKL 366

[Close]

BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A068YDJ8 (Pdz domain containing protein OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000797800 PE=4 SV=1)

HSP 1 Score: 215.312 bits (547), Expect = 5.396e-60
Identity = 137/396 (34.60%), Postives = 220/396 (55.56%), Query Frame = 1

Query:  283 MPFIQKEIILRDGPPWGFRIYEDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFI------EHQGTVQNNAVSKIFLNLTREPL--------TTPASPDLVPVPISKLMKEYDIPPRPENAAKRKRFANSEFFNDPNTYYPTLEEKIEMAKNLAESLTAPVNCKSKGANIFERQRQRIEKYVKEGPDPEPEKELLQIILQDGSVRTLDXXXXXXXXXXXXXXXXXX-GLPTDINKKEIRLPPPPGAPKTLKEYLERIKKYPTVKHDAIGPEKCFTIASALHYGHDRGSNIFQKIRVRSKKWEISSETIKESPVVIFSSKSVNQQKPASKLLSSERKPLDNLNERNIRRNQIKEKSP 1425
            M  +++ I ++ GPPWGFR+ +  N  L+V +IR+ SPA+ A L+E DV+ AIN +S R L+ S AI++I+ +  EL L+V R E    + +TF         Q   Q  A   + ++  +E          T PA P + PV + +L++E++ P +     K++ FANS F+   N YYP++EE+IEMA+ +A+S+ APVN  S+GA +FE Q+QR EK+VKEGP+P P+       L++ + + L+      PPP   P       L + I       PPPPG P++++E++E+++++P   H  I P+ CF IA+ALH    RG  +F K R +++ WE+ S  +    V +   K  ++ K  SK        L+  ++  + R Q +  SP
Sbjct:    1 MQTVERVIHMQQGPPWGFRLADTFNGSLVVSQIRRQSPAEMAGLRENDVVLAINNYSTRGLNRSYAIDIINTSVYELDLVVQRQERRKPQMMTFFLDTSAARGQMVRQEMASRDLDISWRKETAPPPPEPRRTKPADPSVTPVSLDRLLREFEAP-KATPPIKKRTFANSAFYTGTNVYYPSVEEQIEMARRVAKSIEAPVNQGSRGARMFEAQQQRAEKFVKEGPEPIPDP------LENATAQQLEYMIPPAPPPQPPPAAPSFPTLTSTIPPPPPPPPPPPGQPRSIQEFIEKMRRFPKNTHTEISPQVCFDIATALHTSGSRGGAMFAKRRAKAQNWEVESTGVA---VPVLEPKQADRPKLISK--------LEQQHQHQVYRTQQQSTSP 378

[Close]

BLAST of PDZ domain-containing protein vs. TrEMBL
Match: W6V1R2 (Synaptopodin 2-like protein OS=Echinococcus granulosus OX=6210 GN=EGR_00156 PE=4 SV=1)

HSP 1 Score: 212.616 bits (540), Expect = 2.038e-59
Identity = 135/396 (34.09%), Postives = 219/396 (55.30%), Query Frame = 1

Query:  283 MPFIQKEIILRDGPPWGFRIYEDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFI----EHQGTVQNNAVSKIFLNLTREPLTTP----------ASPDLVPVPISKLMKEYDIPPRPENAAKRKRFANSEFFNDPNTYYPTLEEKIEMAKNLAESLTAPVNCKSKGANIFERQRQRIEKYVKEGPDPEPEKELLQIILQDGSVRTLDXXXXXXXXXXXXXXXXXX-GLPTDINKKEIRLPPPPGAPKTLKEYLERIKKYPTVKHDAIGPEKCFTIASALHYGHDRGSNIFQKIRVRSKKWEISSETIKESPVVIFSSKSVNQQKPASKLLSSERKPLDNLNERNIRRNQIKEKSP 1425
            M   ++ I ++ GPPWGFR+ +  N  L+V +IR+ SPA+ A L+E DV+ AIN +S R  + S AI++I+ +  EL L+V R E    + +TF       +G +    ++   L+++    T P          A P + PV + +L++E++ P +     K++ FANS F+   N YYP++EE+IEMA+ +A+S+ APVN  S+GA +FE Q+QR EKYVKEGP+P P+       L++ + + L+      PPP   P       L + I       PPPPG P++++E++E+++++P   H  I P+ CF IA+ALH    RG  +F K R +++ WE+ S  +    V +   K  ++ K  SK        L+  ++  + R Q +  SP
Sbjct:    1 MQTFERVIHMQQGPPWGFRLVDTFNGSLVVSQIRRQSPAEMAGLRENDVVLAINNYSTRGFNRSYAIDVINTSVYELDLVVQRQERRKPQMMTFFLDTSAARGQMVRQEMASRDLDISWRNETAPQPPEPRRIKPADPSVTPVSLDRLLREFEAP-KATPPIKKRTFANSAFYTGTNVYYPSVEEQIEMARRVAKSIEAPVNQGSRGARMFEAQQQRAEKYVKEGPEPIPDP------LENATAQQLEYMIPPAPPPPPPPAAPSFPTLTSTIPPPPPPPPPPPGQPRSIQEFIEKMRRFPKNTHTEISPQVCFDIAAALHTSGSRGGAMFAKRRAKAQSWEVESTGVT---VPVLEPKQADRPKLISK--------LEQQHQHQVYRTQQQSTSP 378

[Close]

BLAST of PDZ domain-containing protein vs. TrEMBL
Match: A0A068W818 (Pdz domain containing protein OS=Echinococcus granulosus OX=6210 GN=EgrG_000797800 PE=4 SV=1)

HSP 1 Score: 212.616 bits (540), Expect = 5.391e-59
Identity = 135/396 (34.09%), Postives = 217/396 (54.80%), Query Frame = 1

Query:  283 MPFIQKEIILRDGPPWGFRIYEDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQGTVQNNAVSKIF----LNLTREPLTTP----------ASPDLVPVPISKLMKEYDIPPRPENAAKRKRFANSEFFNDPNTYYPTLEEKIEMAKNLAESLTAPVNCKSKGANIFERQRQRIEKYVKEGPDPEPEKELLQIILQDGSVRTLDXXXXXXXXXXXXXXXXXX-GLPTDINKKEIRLPPPPGAPKTLKEYLERIKKYPTVKHDAIGPEKCFTIASALHYGHDRGSNIFQKIRVRSKKWEISSETIKESPVVIFSSKSVNQQKPASKLLSSERKPLDNLNERNIRRNQIKEKSP 1425
            M   ++ I ++ GPPWGFR+ +  N  L+V +IR+ SPA+ A L+E DV+ AIN +S R  + S AI++I+ +  EL L+V R E    + +TF       +   V +      L+++    T P          A P + PV + +L++E++ P +     K++ FANS F+   N YYP++EE+IEMA+ +A+S+ APVN  S+GA +FE Q+QR EKYVKEGP+P P+       L++ + + L+      PPP   P       L + I       PPPPG P++++E++E+++++P   H  I P+ CF IA+ALH    RG  +F K R +++ WE+ S  +    V +   K  ++ K  SK        L+  ++  + R Q +  SP
Sbjct:    1 MQTFERVIHMQQGPPWGFRLADTFNGSLVVSQIRRQSPAEMAGLRENDVVLAINNYSTRGFNRSYAIDIINTSVYELDLVVQRQERRKPQMMTFFLDTSAARGQMVRQEMASRDLDISWRKETAPQPPEPRRIKPADPSVTPVSLDRLLREFEAP-KATPPIKKRTFANSAFYTGTNVYYPSVEEQIEMARRVAKSIEAPVNQGSRGARMFEAQQQRAEKYVKEGPEPIPDP------LENATAQQLEYMIPPAPPPPPPPAAPSFPTLTSTIPPPPPPPPPPPGQPRSIQEFIEKMRRFPKNTHTEISPQVCFDIAAALHTSGSRGGAMFAKRRAKAQNWEVESTGVT---VPVLEPKQADRPKLISK--------LEQQHQHQVYRTQQQSTSP 378

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: synpo2lb (synaptopodin 2-like b [Source:ZFIN;Acc:ZDB-GENE-090828-5])

HSP 1 Score: 54.6842 bits (130), Expect = 1.987e-7
Identity = 65/260 (25.00%), Postives = 111/260 (42.69%), Query Frame = 1

Query:  304 IILRDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESM----------CNKNVTF----IEHQGTVQNNAVSKIFLNL-TREPLTTPASPDLVPVPISKLMKEYDIPPRPENAAKRKRFANSEFFNDPNTYYPTLEEK---------------------IEMAKNLAESLTAPVNCKSKGANIFERQRQRIEKY----VKEGPDPEPEKELLQIIL 957
            + L  G PWGFR+    ++ + L V ++R+ S A  A L+E D + +IN      LSHS+A+ LID     L L + R E +           + NV+F    +    +VQ+  V +      T   L T A     P P SK +  +      +   + K  +N+E   +  + +P  E +                     ++   + +  L+A      KGA +FE+QR+R EK+    V   P P P+++   +++
Sbjct:    8 VTLSGGAPWGFRLQGGAEQQKPLQVAKVRKRSKACRAGLREADELMSINDVCCGELSHSEAMNLIDSGRGILQLRIKRSEPVYDVPLNVKKNISLNVSFSSTELHRSESVQDKQVKEARTKCRTIASLLTDA-----PNPHSKGVLMFK-----KRRQRAKNLSNTEGETEDESLFPGSESELDEDCFSAAPDPTWDSGYLDILDRRTSGSPGLSA---TSGKGAQLFEQQRKRAEKHTSTPVTLTPAPMPQQQPNNMMM 254

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: synpo2lb (synaptopodin 2-like b [Source:ZFIN;Acc:ZDB-GENE-090828-5])

HSP 1 Score: 54.299 bits (129), Expect = 2.474e-7
Identity = 30/82 (36.59%), Postives = 45/82 (54.88%), Query Frame = 1

Query:  304 IILRDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESM 543
            + L  G PWGFR+    ++ + L V ++R+ S A  A L+E D + +IN      LSHS+A+ LID     L L + R E +
Sbjct:    8 VTLSGGAPWGFRLQGGAEQQKPLQVAKVRKRSKACRAGLREADELMSINDVCCGELSHSEAMNLIDSGRGILQLRIKRSEPL 89

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: synpo2lb (synaptopodin 2-like b [Source:ZFIN;Acc:ZDB-GENE-090828-5])

HSP 1 Score: 54.299 bits (129), Expect = 2.942e-7
Identity = 30/80 (37.50%), Postives = 44/80 (55.00%), Query Frame = 1

Query:  304 IILRDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHE 537
            + L  G PWGFR+    ++ + L V ++R+ S A  A L+E D + +IN      LSHS+A+ LID     L L + R E
Sbjct:    8 VTLSGGAPWGFRLQGGAEQQKPLQVAKVRKRSKACRAGLREADELMSINDVCCGELSHSEAMNLIDSGRGILQLRIKRSE 87

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Match: synpo2lb (synaptopodin 2-like b [Source:ZFIN;Acc:ZDB-GENE-090828-5])

HSP 1 Score: 53.9138 bits (128), Expect = 3.651e-7
Identity = 30/80 (37.50%), Postives = 44/80 (55.00%), Query Frame = 1

Query:  304 IILRDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHE 537
            + L  G PWGFR+    ++ + L V ++R+ S A  A L+E D + +IN      LSHS+A+ LID     L L + R E
Sbjct:    8 VTLSGGAPWGFRLQGGAEQQKPLQVAKVRKRSKACRAGLREADELMSINDVCCGELSHSEAMNLIDSGRGILQLRIKRSE 87

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002484.1 (pep scaffold:Pmarinus_7.0:GL476548:370238:411117:1 gene:ENSPMAG00000002245.1 transcript:ENSPMAT00000002484.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 47.3654 bits (111), Expect = 5.053e-6
Identity = 27/77 (35.06%), Postives = 41/77 (53.25%), Query Frame = 1

Query:  298 KEIILRDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLL 522
            +++IL    PWGFR+    D ++ L + R+   S A +A L  GDVI AI   +A  ++H++A E I       L L
Sbjct:    3 QQVILTGPAPWGFRLVGGRDLDQPLTISRVTPGSVASSANLSPGDVILAIEGENAEEMTHAEAQERIKACSTATLTL 79

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: synpo2lb (synaptopodin 2-like protein [Source:NCBI gene;Acc:101157330])

HSP 1 Score: 53.1434 bits (126), Expect = 6.589e-7
Identity = 30/79 (37.97%), Postives = 46/79 (58.23%), Query Frame = 1

Query:  301 EIILRDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGR 531
            E+ L  G PWGFR+    ++++ L V ++R+ S A  A LKE D + +I+  +   LSH+ A++LID     L L V R
Sbjct:    7 EVSLTGGAPWGFRLQGGAEQHKPLQVAKVRKRSKACRAGLKEQDELVSIDDHTCAELSHAQAMKLIDSESATLKLKVKR 85

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: pdlim3a (PDZ and LIM domain 3 [Source:NCBI gene;Acc:101158506])

HSP 1 Score: 51.2174 bits (121), Expect = 1.666e-6
Identity = 33/81 (40.74%), Postives = 45/81 (55.56%), Query Frame = 1

Query:  307 ILRDGP-PWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHES 540
            ++ DGP PWGFR+    D N+ L + RI   S A +A L  GDVI AI    A  + H +A   I  + K+L L V R++S
Sbjct:   38 VVLDGPAPWGFRLTGGRDFNQPLTISRITPGSKASSANLCPGDVILAIEGVPATDMLHCEAQNKIKESSKQLCLTVERNQS 118

[Close]

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Match: ldb3b (LIM domain-binding protein 3 [Source:NCBI gene;Acc:101168991])

HSP 1 Score: 48.9062 bits (115), Expect = 5.024e-6
Identity = 31/93 (33.33%), Postives = 48/93 (51.61%), Query Frame = 1

Query:  307 ILRDGP-PWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQ 576
            +  +GP PWGFR+   +D N  L + RI   S A    L +GD+I+AI+  S   L+H +A   I++T ++    V       +  +T I HQ
Sbjct:    6 VTLNGPAPWGFRLQGGKDFNMPLTISRITPASKAAGGSLAQGDIITAIDGVSTEGLTHLEAQNKINLTLQKFRTPVPTATPRMDSPMTVIAHQ 98

[Close]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Match: SMESG000012918.1 (SMESG000012918.1)

HSP 1 Score: 756.903 bits (1953), Expect = 0.000e+0
Identity = 391/395 (98.99%), Postives = 393/395 (99.49%), Query Frame = 1

Query:  283 MPFIQKEIILRDGPPWGFRIYEDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQGTVQNNAVSKIFLNLTREPLTTPASPDLVPVPISKLMKEYDIPPRPENAAKRKRFANSEFFNDPNTYYPTLEEKIEMAKNLAESLTAPVNCKSKGANIFERQRQRIEKYVKEGPDPEPEKELLQIILQDGSVRTLDXXXXXXXXXXXXXXXXXXGLPTDINKKEIRLPPPPGAPKTLKEYLERIKKYPTVKHDAIGPEKCFTIASALHYGHDRGSNIFQKIRVRSKKWEISSETIKESPVVIFSSKSVNQQKPASKLLSSERKPLDNLNERNIRRNQIKEKSPNQWRPVKFIVPSHM 1467
            MPFIQKEIILRDGPPWGFRIYEDENRGLIVHRIRQWSPAQTAKLKEGDVI AINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQGTVQNNAVSKIFLNLTREPLTTPASPDLVPVPISKLMKEYDIPPRPENAAKRKRFANSEFFNDPNTYYPTLEEKIEMAKNLAESLTAPVNCKSKGANIFERQRQRIEKYVKEGPDPEPEKELLQIILQDGSVRTLDPPEIEPPPPLNSPPVGFPGLPTDINKKEIRLPPPPGAPKTLKEYLERIKKYPTVKHDAIGPEKCFTIASALHYGHDRGSNIFQKIR+RSKKWEISSETIKESPVVIFSSK VNQQKPASKLLSSERKPLDNLNERNI+RNQIKEKSPNQWRPVKFIVPSHM
Sbjct:    1 MPFIQKEIILRDGPPWGFRIYEDENRGLIVHRIRQWSPAQTAKLKEGDVILAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQGTVQNNAVSKIFLNLTREPLTTPASPDLVPVPISKLMKEYDIPPRPENAAKRKRFANSEFFNDPNTYYPTLEEKIEMAKNLAESLTAPVNCKSKGANIFERQRQRIEKYVKEGPDPEPEKELLQIILQDGSVRTLDPPEIEPPPPLNSPPVGFPGLPTDINKKEIRLPPPPGAPKTLKEYLERIKKYPTVKHDAIGPEKCFTIASALHYGHDRGSNIFQKIRIRSKKWEISSETIKESPVVIFSSKYVNQQKPASKLLSSERKPLDNLNERNIQRNQIKEKSPNQWRPVKFIVPSHM 395

[Close]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Match: SMESG000051965.1 (SMESG000051965.1)

HSP 1 Score: 215.312 bits (547), Expect = 2.451e-63
Identity = 142/380 (37.37%), Postives = 207/380 (54.47%), Query Frame = 1

Query:  283 MPFIQKEIILRDGPPWGFRIYEDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFI-EHQGTVQNNAVSKIFLNLTR------------------------EP-----LTTPASPDLVPVPISKLMKEYDIPPRPEN-AAKRKRFANSEFFNDPNTYYPTLEEKIEMAKNLAESLTAPVNCKSKGANIFERQRQRIEKY-VKEGPDP-------EPEKELLQIILQDGSVRTLDXXXXXXXXXXXXXXXXXXGLPTDINKKEIRLPPPPGAPKTLKEYLERIKKYPTVKHDAIGPEKCFTIASALHYGHDRGSNIFQKIRVRSKKWEISS-ETIKESPVVI 1302
            MP ++K  IL  GPPWGFR+Y D N  L + +IR+ SPA++A L  GD I  +N  S   +SH++A+  ID T   L L + R ES+  K +T + + +  +     SK+ L+LTR                        EP     L  P+SPD+ P+ ISKL+K++     P N   K+K+FA+S F++DP   YPT+EEK++MA+ +A SLTAP N  SKGA+IFERQR+R EKY +K   D        EP+K  L+   Q    R   P  +      +   V  P  P      E          K+++E++E+++K+P  KH+ I P+ CF IA+ALH    RG+ IF + + RSKKWE+S+ E  +  PV++
Sbjct:    1 MPSVEKRFILTKGPPWGFRLYADNNGVLTISKIRRHSPAESANLHSGDQILKLNGKSTAGMSHAEAVNFIDTTIGTLDLQITRFESVSTKILTSVPKAEIDILETVKSKMNLDLTRSEKSPDIPKVPSCTPEVETKKEIEEPPVAKDLIIPSSPDVQPIEISKLIKDFTDSEEPYNYVPKKKQFADSAFYSDPQNLYPTMEEKVQMARRVATSLTAPDNKSSKGASIFERQRKRAEKYTLKNKEDSPVNSRPVEPQKYDLEHWPQVMEPREKSPSPMYRLGYSSKQCVPPPPPPPPPPPNET---------KSIQEFMEKVQKFPKTKHNEITPQTCFDIAAALHSSTSRGAQIFAQKKNRSKKWELSTPEPTQPQPVMV 371

[Close]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Match: SMESG000064215.1 (SMESG000064215.1)

HSP 1 Score: 62.003 bits (149), Expect = 4.849e-11
Identity = 35/82 (42.68%), Postives = 50/82 (60.98%), Query Frame = 1

Query:  301 EIIL---RDGPPWGFRIY--EDENRGLIVHRIRQWSPAQTAKLKEGDVISAINRFSARYLSHSDAIELIDVTFKELLLLVGR 531
            E+IL    +G PWGFRI    D +  L V +++  SP+ + KL+ GD I  IN F+   L HS+AIELI  + K+L L++ R
Sbjct:   75 EVILERNSEGEPWGFRIQGGHDYHLQLSVKKVKSGSPSDS-KLQSGDAIIKINGFATHNLCHSEAIELIKCSSKKLSLIIAR 155

The following BLAST results are available for this feature:

BLAST of PDZ domain-containing protein vs. Ensembl Human
BLAST of PDZ domain-containing protein vs. Ensembl Celegans
BLAST of PDZ domain-containing protein vs. Ensembl Fly
BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
BLAST of PDZ domain-containing protein vs. Ensembl Mouse
BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
BLAST of PDZ domain-containing protein vs. TrEMBL
BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
BLAST of PDZ domain-containing protein vs. Ensembl Sea Lamprey
BLAST of PDZ domain-containing protein vs. Ensembl Yeast
BLAST of PDZ domain-containing protein vs. Ensembl Nematostella
BLAST of PDZ domain-containing protein vs. Ensembl Medaka
BLAST of PDZ domain-containing protein vs. Planmine SMEST

BLAST of PDZ domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SYNPO2L	5.400e-9	41.03	synaptopodin 2 like [Source:HGNC Symbol;Acc:HGNC:2...	[more]
PDLIM3	3.623e-8	38.27	PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDLIM3	8.065e-8	37.35	PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDLIM3	8.489e-8	37.35	PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDLIM3	1.009e-7	37.35	PDZ and LIM domain 3 [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PDZ domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Zasp66	1.449e-8	36.00	gene:FBgn0035917 transcript:FBtr0089563	[more]
Zasp66	1.478e-8	36.00	gene:FBgn0035917 transcript:FBtr0301154	[more]
Zasp66	1.845e-8	36.00	gene:FBgn0035917 transcript:FBtr0301156	[more]
Zasp66	2.064e-8	36.00	gene:FBgn0035917 transcript:FBtr0089568	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
synpo2la	6.235e-8	33.62	synaptopodin 2-like a [Source:ZFIN;Acc:ZDB-GENE-09...	[more]
pdlim3a	4.358e-7	40.45	PDZ and LIM domain 3a [Source:ZFIN;Acc:ZDB-GENE-05...	[more]
synpo2la	4.629e-7	39.74	synaptopodin 2-like a [Source:ZFIN;Acc:ZDB-GENE-09...	[more]
pdlim3a	4.810e-7	40.45	PDZ and LIM domain 3a [Source:ZFIN;Acc:ZDB-GENE-05...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
foxi4.2	1.025e-6	34.94	forkhead box I4, gene 2 [Source:Xenbase;Acc:XB-GEN...	[more]
foxi4.2	1.163e-6	34.94	forkhead box I4, gene 2 [Source:Xenbase;Acc:XB-GEN...	[more]
foxi4.2	1.210e-6	34.94	forkhead box I4, gene 2 [Source:Xenbase;Acc:XB-GEN...	[more]
foxi4.2	1.451e-6	34.94	forkhead box I4, gene 2 [Source:Xenbase;Acc:XB-GEN...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Synpo2l	1.458e-8	39.24	synaptopodin 2-like [Source:MGI Symbol;Acc:MGI:191...	[more]
Pdlim3	1.153e-7	36.14	PDZ and LIM domain 3 [Source:MGI Symbol;Acc:MGI:18...	[more]
Pdlim3	1.394e-7	36.14	PDZ and LIM domain 3 [Source:MGI Symbol;Acc:MGI:18...	[more]
Synpo2l	6.913e-7	39.74	synaptopodin 2-like [Source:MGI Symbol;Acc:MGI:191...	[more]
Pdlim4	2.130e-6	30.19	PDZ and LIM domain 4 [Source:MGI Symbol;Acc:MGI:13...	[more]

BLAST of PDZ domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9H987\|SYP2L_HUMAN	2.593e-8	41.03	Synaptopodin 2-like protein OS=Homo sapiens OX=960...	[more]
sp\|Q9PU47\|PDLI3_CHICK	4.016e-8	40.96	PDZ and LIM domain protein 3 OS=Gallus gallus OX=9...	[more]
sp\|Q66HS7\|PDLI3_RAT	3.905e-7	36.14	PDZ and LIM domain protein 3 OS=Rattus norvegicus ...	[more]
sp\|Q53GG5\|PDLI3_HUMAN	4.077e-7	37.35	PDZ and LIM domain protein 3 OS=Homo sapiens OX=96...	[more]
sp\|Q6QGC0\|PDLI3_PIG	5.062e-7	37.35	PDZ and LIM domain protein 3 OS=Sus scrofa OX=9823...	[more]

BLAST of PDZ domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A158QV81	3.514e-61	36.44	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A5K3EX68	1.690e-60	36.17	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A068YDJ8	5.396e-60	34.60	Pdz domain containing protein OS=Echinococcus mult...	[more]
W6V1R2	2.038e-59	34.09	Synaptopodin 2-like protein OS=Echinococcus granul...	[more]
A0A068W818	5.391e-59	34.09	Pdz domain containing protein OS=Echinococcus gran...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
synpo2lb	1.987e-7	25.00	synaptopodin 2-like b [Source:ZFIN;Acc:ZDB-GENE-09...	[more]
synpo2lb	2.474e-7	36.59	synaptopodin 2-like b [Source:ZFIN;Acc:ZDB-GENE-09...	[more]
synpo2lb	2.942e-7	37.50	synaptopodin 2-like b [Source:ZFIN;Acc:ZDB-GENE-09...	[more]
synpo2lb	3.651e-7	37.50	synaptopodin 2-like b [Source:ZFIN;Acc:ZDB-GENE-09...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000002484.1	5.053e-6	35.06	pep scaffold:Pmarinus_7.0:GL476548:370238:411117:1...	[more]

BLAST of PDZ domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PDZ domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of PDZ domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
synpo2lb	6.589e-7	37.97	synaptopodin 2-like protein [Source:NCBI gene;Acc:...	[more]
pdlim3a	1.666e-6	40.74	PDZ and LIM domain 3 [Source:NCBI gene;Acc:1011585...	[more]
ldb3b	5.024e-6	33.33	LIM domain-binding protein 3 [Source:NCBI gene;Acc...	[more]

BLAST of PDZ domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000012918.1	0.000e+0	98.99	SMESG000012918.1	[more]
SMESG000051965.1	2.451e-63	37.37	SMESG000051965.1	[more]
SMESG000064215.1	4.849e-11	42.68	SMESG000064215.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30023885 ID=SMED30023885|Name=PDZ domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1647bp
AACTAATCGATTTCCCTCTTGCACGCAATTGTACTTTTATCCACAGCTCG
ATTGAAGCATGATGAAATGATATTTCAGCAACATTGGACCAATGCAATGT
CGAGTGTGCCGAGTGAACTGGATTTGGTCAATAGCAGCAAGAAATTGGTG
ATAAAATATACAATTGCATCAAATCGAAATAATTTTCCTTTTCAAAATAT
TCCAATCAAACAATTAATTTCCTAATTTGTTTTCGAGTACTAATTCACTT
CTTTTTCGATTTTAATTTTGTGGAATTTATAAATGCCTTTCATACAGAAA
GAGATAATTCTTCGCGATGGACCTCCATGGGGATTTAGAATTTATGAAGA
TGAAAACCGAGGATTAATTGTTCATAGAATTCGTCAATGGAGTCCGGCTC
AAACTGCAAAGTTAAAAGAAGGCGATGTTATCTCAGCCATTAATCGATTT
TCTGCTAGATATTTAAGCCATTCAGACGCCATTGAACTTATAGATGTCAC
TTTCAAAGAACTTCTACTCTTGGTCGGCAGACATGAATCAATGTGTAATA
AAAATGTAACGTTTATTGAACACCAAGGAACTGTACAAAATAATGCAGTA
TCGAAAATATTTTTGAATTTAACAAGAGAACCTTTGACAACACCCGCCTC
TCCCGATTTAGTTCCAGTGCCAATCAGTAAATTAATGAAAGAATACGATA
TTCCACCTCGGCCGGAAAATGCAGCAAAAAGAAAACGATTTGCGAATTCT
GAATTTTTTAATGATCCCAACACATATTATCCGACCTTGGAAGAGAAAAT
TGAAATGGCAAAGAACTTAGCTGAAAGTTTGACAGCTCCAGTAAATTGCA
AATCAAAAGGGGCAAATATATTTGAAAGGCAACGGCAAAGAATTGAAAAA
TATGTTAAAGAGGGTCCGGATCCAGAACCAGAAAAGGAACTTCTCCAAAT
TATTCTGCAAGATGGATCGGTAAGAACACTTGATCCACCTGAGATCGAAC
CTCCACCTCCACTTAATTCTCCGCCAGTCGGATTCCCTGGTTTACCAACA
GATATTAATAAAAAGGAAATTCGTCTTCCACCTCCACCTGGAGCCCCGAA
AACATTGAAAGAATACTTGGAAAGAATTAAAAAATATCCAACAGTAAAAC
ATGATGCAATCGGTCCAGAAAAATGTTTTACTATTGCCTCTGCATTACAT
TATGGTCACGATAGAGGGTCAAATATATTTCAAAAAATAAGAGTTCGATC
GAAAAAGTGGGAAATCTCTAGCGAAACCATTAAAGAAAGTCCTGTAGTTA
TATTTTCATCAAAATCCGTAAATCAACAAAAGCCAGCATCAAAACTATTG
TCTTCCGAAAGGAAACCTTTAGATAATTTAAATGAAAGAAATATCCGGCG
GAATCAAATAAAAGAAAAGTCTCCAAACCAATGGAGACCAGTGAAATTCA
TAGTTCCTTCACATATGTGAATAATACGAGATCAGTTGCAAAAAGATTGA
AACAACTTATTTGTCATTTGTACTATTTTCTTAAGTTTATTTAGAGGTTT
TATTCCCTAGCATTAGAATTATTTTACTAACTCCATTTAAGTTGTTCCAT
AGATAGTGTAGAAATAATTAAAACAAACTATCATTTTATTTGAAACG

protein sequence of SMED30023885-orf-1

>SMED30023885-orf-1 ID=SMED30023885-orf-1|Name=SMED30023885-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=396bp
MPFIQKEIILRDGPPWGFRIYEDENRGLIVHRIRQWSPAQTAKLKEGDVI
SAINRFSARYLSHSDAIELIDVTFKELLLLVGRHESMCNKNVTFIEHQGT
VQNNAVSKIFLNLTREPLTTPASPDLVPVPISKLMKEYDIPPRPENAAKR
KRFANSEFFNDPNTYYPTLEEKIEMAKNLAESLTAPVNCKSKGANIFERQ
RQRIEKYVKEGPDPEPEKELLQIILQDGSVRTLDPPEIEPPPPLNSPPVG
FPGLPTDINKKEIRLPPPPGAPKTLKEYLERIKKYPTVKHDAIGPEKCFT
IASALHYGHDRGSNIFQKIRVRSKKWEISSETIKESPVVIFSSKSVNQQK
PASKLLSSERKPLDNLNERNIRRNQIKEKSPNQWRPVKFIVPSHM*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell
PLANA:0000140	anterior region of the whole animal
PLANA:0003104	enteric muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036034	PDZ_sf
IPR004172	L27_dom
IPR001478	PDZ

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0003779	actin binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0015629	actin cytoskeleton
GO:0016607	nuclear speck
GO:0030018	Z disc

Vocabulary: **biological process**
Term	Definition
GO:0032233	positive regulation of actin filament bundle assembly

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001478	PDZ domain	SMART	SM00228	pdz_new	coord: 14..85 e-value: 4.2E-6 score: 36.3
IPR001478	PDZ domain	PFAM	PF00595	PDZ	coord: 15..81 e-value: 2.8E-8 score: 34.0
IPR001478	PDZ domain	PROSITE	PS50106	PDZ	coord: 13..85 score: 13.571
IPR036034	PDZ superfamily	GENE3D	G3DSA:2.30.42.10		coord: 4..97 e-value: 6.4E-17 score: 63.1
IPR036034	PDZ superfamily	SUPERFAMILY	SSF50156	PDZ domain-like	coord: 4..87
None	No IPR available	PANTHER	PTHR24217	FAMILY NOT NAMED	coord: 8..124
None	No IPR available	PANTHER	PTHR24217:SF10	SYNAPTOPODIN 2-LIKE PROTEIN	coord: 8..124
None	No IPR available	CDD	cd00992	PDZ_signaling	coord: 6..81 e-value: 3.4302E-15 score: 68.3622

Main menu

PDZ domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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