Rootletin-2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30023882 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 30Note: Hover over icons to view figure legend
Homology
BLAST of Rootletin-2 vs. Ensembl Human
Match: CROCC (ciliary rootlet coiled-coil, rootletin [Source:HGNC Symbol;Acc:HGNC:21299]) HSP 1 Score: 785.793 bits (2028), Expect = 0.000e+0 Identity = 694/2093 (33.16%), Postives = 1157/2093 (55.28%), Query Frame = 1
Query: 271 GIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNC--SQLENSLSKMKEEFRKTETQYQKQIES------LNEQFVHVNRSNESLTKELADKEKV-------LTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVD---QVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSS--RNSVEFNFSEDRKRVGRFGDVNQYS--------------ESVIPGS-DLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSAL--KSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMEL-TSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKK 6435
G+G DL+ + +P ++++I+ R+ +Q S + + S+ L+ EN L+ L VE+ L + + ERD LAIK+NA++E+L + R+ E L Q+++LR+QL ++ Y+RKL A + Q +QA+L++RLQ K+ Q + R S L+ L R ++ + L+ +T+ + DLES + L+EEQ +S SL Q+ A+LR+QLD+A +ANQ L+ED+++++ + + + ELE ++ W+ +E +F+ + E +R+ LW VV F+R +++K ERDL QL + +++++++ A L T RL++ + + EK +QLE L +++ + + Q+Q++S L+ + + + + L K+ +K++V L L LR L+ D + + Q LRD+AQ V++D + Q+ S D + G S+ L R+ SP R RS G R R SP ST A + SALHKR LQVQD+ + ++++ +++KQL DSE+ERR LE+Q LR + D + +D QRE +R+R +L +K L S + ++ + +Q+ EKL+ EL+R ++ L + +D ++ R +E+ER + +E E K S L +E+ ++E+L+RA L++++L+ E + + ++L K E + E E+ K + EEA L+D +L ++N L ++ + ++ Q E EK L G ++ EQE REE R+E + E + GL S++ E++ E L+ +L L +E+ QL+ L R+ + EL QARR+A+R A++++ ++KE LAKE L QL E E R ++ L+ EKE L+GSL+E Q+ ++QLEA+ E LE+ Q L + + E L+ + +K S KE + KL ++E+E LR ++ A EED++RL E+E E + +++ Q Q E ++L RL +KEEL++EI +Q+ERD+ LL AE KQ A++L E EK ++ EK+ L T ++ER + + + R +QD++T+ +L+ R Q E+ H +E++ LQ ++L Q+ +RE EEL++ L++ E+ RD LR++L E+ K+RE+++ RE R+E + +R+ E KE E ++ SN+ELR +K +E ++I ++ +D + KL++LEE + + KE + R LQ+ E++R++ RREL+ELR Q+K LD+E +L E++ LQ R+A E E E+RRE GL+Q++++ EA+ E + ++L + RK +E E ++E+ +E K + LE +LE EL LS E R LE ++ ++ +R+ AE +L + S LR+ +G GR S V + + D G +N S + P S DLDPEAVR ALR+ Q + S +RERD E++ + SAL + E + D A R QLQK E EE ++ +D RLS Q L +QEE++ R+ERER++ +D+V LER L E+E + QE++ KM+ E+ E ++R L + +D +E+R +LEL RR LEGELQR ++G +D+E + Q L+DRVD+L +Q++D E KA +LQLT++RL+ LA+ EE E +DKV L +L++ +L S +DK + LQ L + EHDR+VLQERL++ + LSEA+ Q+ +L ++++ + E+ + E ++ E EG++++L ++L QRQE E + + + E+ LL ERL SL +LA LE+E+R++E+ ++ EK++ +L++TLDK+E+EK RS E + ++ D E E RQ+Q+L+ Q+ EQ H+ +E+ + + E+ E++RL+SA TE+TL+ RER+HRQ+V+ LEEQ++ LK QL QEL++
Sbjct: 32 GLGARDLAQDAQITSLPALIREIVTRNL----------------------SQPESPVLLPATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQAL--------RLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKR-----------------CSELEQQL------LERSGELEQQRLR--DTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGL--RLAESRAEAALEKQALLQAQLEEQL---RDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETE--------------DGEGLQQTLRDLAQAVLSDSESGVQLSGSERTAD------ASNG------SLRGLSGQRTPSPPR---RSSPGRGRSPR----RGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGL--------------------------GRAPSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRERD--ELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKGQLQQELRR 2003
BLAST of Rootletin-2 vs. Ensembl Human
Match: CROCC (ciliary rootlet coiled-coil, rootletin [Source:HGNC Symbol;Acc:HGNC:21299]) HSP 1 Score: 482.641 bits (1241), Expect = 1.929e-142 Identity = 424/1317 (32.19%), Postives = 731/1317 (55.50%), Query Frame = 1
Query: 844 LNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNC--SQLENSLSKMKEEFRKTETQYQKQIES------LNEQFVHVNRSNESLTKELADKEKV-------LTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVD---QVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGF 4740
L ++N L+ E+SR+++ + ++ + + I N + +T+ + DLES + L+EEQ +S SL Q+ A+LR+QLD+A +ANQ L+ED+++++ + + + ELE ++ W+ +E +F+ + E +R+ LW VV F+R +++K ERDL QL + +++++++ A L T RL++ + + EK +QLE L +++ + + Q+Q++S L+ + + + + L K+ +K++V L L LR L+ D + + Q LRD+AQ V++D + Q+ S D + G S+ L R+ SP R RS G R R SP ST A + SALHKR LQVQD+ + ++++ +++KQL DSE+ERR LE+Q LR + D + +D QRE +R+R +L +K L S + ++ + +Q+ EKL+ EL+R ++ L + +D ++ R +E+ER + +E E K S L +E+ ++E+L+RA L++++L+ E + + ++L K E + E E+ K + EEA L+D +L ++N L ++ + ++ Q E EK L G ++ EQE REE R+E + E + GL S++ E++ E L+ +L L +E+ QL+ L R+ + EL QARR+A+R A++++ ++KE LAKE L QL E E R ++ L+ EKE L+GSL+E Q+ ++QLEA+ E LE+ Q L + + E L+ + +K S KE + KL ++E+E LR ++ A EED++RL E+E E + +++ Q Q E ++L RL +KEEL++EI +Q+ERD+ LL AE KQ A++L E EK ++ EK+ L T ++ER + + + R +QD++T+ +L+ R Q E+ H +E++ LQ ++L Q+ +RE EEL++ L++ E+ RD LR++L E+ K+RE+++ RE R+E + +R+ E KE E ++ SN+ELR +K +E ++I ++ +D + KL++LEE + + KE + R LQ+ E++R++ RREL+ELR Q+K LD+E +L E++ LQ R+A E E E+RRE GL+Q++++ EA+ E + ++L + RK +E E ++E+ +E K + LE +LE EL LS E R LE ++ ++ +R+ AE +L + S LR+ +G
Sbjct: 29 LQEENQLLQQELSRVEDLLAQSRAERDE-LAIKYNAVSERDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGL--RLAESRAEAALEKQALLQAQLEEQL---RDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETE--------------DGEGLQQTLRDLAQAVLSDSESGVQLSGSERTAD------ASNG------SLRGLSGQRTPSPPR---RSSPGRGRSPR----RGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGL 1306
BLAST of Rootletin-2 vs. Ensembl Human
Match: CROCC (ciliary rootlet coiled-coil, rootletin [Source:HGNC Symbol;Acc:HGNC:21299]) HSP 1 Score: 276.559 bits (706), Expect = 5.760e-77 Identity = 234/780 (30.00%), Postives = 407/780 (52.18%), Query Frame = 1
Query: 685 QTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNC--SQLENSLSKMKEEFRKTETQYQKQIES------LNEQFVHVNRSNESLTKELADKEKV-------LTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVD---QVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQL------ETANVTLQRERNALSTEL 2952
Q+++LR+QL ++ Y+RKL A + Q +QA+L++RLQ K+ Q + R S L+ L R ++ + L+ +T+ + DLES + L+EEQ +S SL Q+ A+LR+QLD+A +ANQ L+ED+++++ + + + ELE ++ W+ +E +F+ + E +R+ LW VV F+R +++K ERDL QL + +++++++ A L T RL++ + + EK +QLE L +++ + + Q+Q++S L+ + + + + L K+ +K++V L L LR L+ D + + Q LRD+AQ V++D + Q+ S D + G S+ L R+ SP R RS G R R SP ST A + SALHKR LQVQD+ + ++++ +++KQL DSE+ERR LE+Q LR + D + +D QRE +R+R +L +K L S + ++ + +Q+ EKL+ EL+R ++ L + +D ++ R +E+ER + +E E K S L +E+ ++E+L+RA L++++L+ E + + ++L K E + E E+ K + EEA L+D +L ++N L ++ + ++ Q E EK L G ++ EQE REE R+E + E + GL S++ E++ E L+ +L L +E+ QL E A L+ ER L ++L
Sbjct: 34 QSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKR-----------------CSELEQQL------LERSGELEQQRLR--DTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGL--RLAESRAEAALEKQALLQAQLEEQL---RDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETE--------------DGEGLQQTLRDLAQAVLSDSESGVQLSGSERTAD------ASNG------SLRGLSGQRTPSPPR---RSSPGRGRSPR----RGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQEAAWRELEAERAQLQSQL 750
BLAST of Rootletin-2 vs. Ensembl Human
Match: CROCC2 (ciliary rootlet coiled-coil, rootletin family member 2 [Source:HGNC Symbol;Acc:HGNC:51677]) HSP 1 Score: 254.603 bits (649), Expect = 3.246e-67 Identity = 395/1526 (25.88%), Postives = 701/1526 (45.94%), Query Frame = 1
Query: 886 LKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLAC----SNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERM-----RHTISMLEEDKLKLDKSRMNSYE-ECKSYKQDMEK--LKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLE--TANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIE--ALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAE--MGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTE-----------RGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSD----LDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERR---GLIK 5355
L + + + L R++ E L+ +E + ++DLE + L+ + +S L Q+ ALLR+QL+ AN L ++ ++ L+ ELE + W + T S L G+ + LW V +++ + ER L L+ + ++ + L AC SNL + + S L QL + QL+ + + K Q + L+EQ + V E LT++ K K + L DL N + D +L + + ++ + P + S R+ SP + + H S P ++ D A+R+A+ +R + Q+L ++ S++ S+++QL +S E +K + R+ + RE Q E +R+ R + +L +K L+ M E + K+ D EK L+ ELQR + ++L ER + +E ++ E K S L+EE++S++E+L+ A L+++V+E E L +L + E A+ E+ + K+E RD + ++ L ++ S + Q E E+ +L ++K LEQE+ E+L + E + + GL Q+ +E+ E L+ + + L EK QL+ VT Q++ AL +L Q+ +D E +Q++++ K+ L++E+ L+++ E + R A+ L+ E++ L+ SL E+QQ ++L+ ++E A + L R + E ++LQ +++V+ KL + LQ ++ + E+E + L S+ A E + +L E+E L + KE + Q ++E +L + ++E L EI ++++ERD+ LL+ E M + A++L E E+ + E++S+ + LER + E + + +Q Q TI +LK + QFE H RE L+ + ++L ++ RE E L++ L +A+E LRQ+L + E+ RE L RE + +R + +E + + L N ELR + +E +K +R ++ + KL ILEE + LQ+E R +L + E+A D R+EL EL QV+ L E + + EV L+ + A E K AR+E GL++K+ E EA E ++L + LR++ E+ L + E+ + L+E+ + + L + L +RI LE ++ + R+ AE +L + S LR+ +G ++Q + SP KG S +S + R ++ S PG +D V+ LRD Q + +RERDD I+ + + E + +A R+ QLQK E EE ++ ++ LSSA+ A +Q+E + R E E + + G+ EK+ LQE+++ +R EE RR GL K
Sbjct: 117 LASRCRVVSEQLQARLETTEAQLRRSELEHSVDLEEALGRLEAAEERSTGLCQVNALLREQLEHMKKANDALGRELAGMTGSVQRLQGELELRR--WAQRQ-TRSGGL-GQPRDLLLLWRQAVVLGTDLAELRVATERGLADLQADTARTARRLHTACLNLDSNLRLSASSTASTLGQQLRDKAGEMLQLQG-----RWDAEKVALQAR-----LSEQTLLV----EKLTEQNEQKAKTIAALRT-------DLQNLVAQEDARCL------------------ELAGSSITELGE-------------------PRRPLRS--PQRATSPHQGASPPHICS-------------PATL-DPALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELWAAQK-LQQERAREQAREREALRGQLEAQRLEVQQCRASCKLLGREKAALE---MVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQ--ALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGL-----ARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQE-KELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQVMALSLKETERSLLSEELSR-------ARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQEL-------QGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRESRGAEQTLRA----------ELHSVTRKLQEA-----------SGVADALQARLDQACHRIHSLEQELAQAEGARQDAEAQLGRLCSTLRRGLGLQRQ---------SPWASPEQPGSPTKG---SDSSQALPGQQGTSPPARPHSPLRWP-SPTPGGRSSELMDVATVQDILRDFVQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARAARALQKEALRRLELEHLASVRAAGQ----------EKRRLQEQLETLR---QALEESRRHSQGLAK 1491 HSP 2 Score: 63.5438 bits (153), Expect = 6.083e-9 Identity = 35/83 (42.17%), Postives = 57/83 (68.67%), Query Frame = 1
Query: 6193 RQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRE 6441
RQ Q+LQ Q+ E EQ H QR+ +LT++ + ++ +E +RL A + L+ +E +H+Q+VK LEEQ+ LK+QL QE++ R+
Sbjct: 1557 RQNQQLQAQMTEMEQAHTQRLQDLTAQHQRDLATEAERLHGARPQATQALESQEWTHQQQVKVLEEQVASLKEQLDQEVQWRQ 1639
BLAST of Rootletin-2 vs. Ensembl Human
Match: CEP250 (centrosomal protein 250 [Source:HGNC Symbol;Acc:HGNC:1859]) HSP 1 Score: 172.94 bits (437), Expect = 4.073e-42 Identity = 291/1208 (24.09%), Postives = 555/1208 (45.94%), Query Frame = 1
Query: 685 QTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNL-------DTNHVNRL-----SQLQF------QLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNE---SLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQ-------EIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELE------TIQLSNKELR----EKLKTSEMQKIDIQRQ-LQDLQNKLSILEEQKQVLQKEVKD 4191
Q + L++Q+ ++ RKL + Q +QA L+++LQ K+ Q RS L+ + T + +R + E + N+D ++ L+EEQ + SL ++ LR +++A N+ L EDV++L+ + S + EL +K+ W+ ++ F +L GE R+ SLW VV F+R F ++KS+ +RDL +L+ + + SL C L + N R+ +QL +L+ E + SQ L ++K + + + Q ++ L+ + NE + K L + ++L T H + ++ S +R + ++ Q ++DI Q+++ + D + ++ +G NSL + S+ S F+ Y++ AD VRS L +R VQDL ++ + N +++Q D E E + L ++ +L E D+ + D+Q E + L +++ L K+R ++ + +Q+ +L+ +N ELQ ++ ++ L +E ERL + + E+K S E+ +L+E+L + LE E+L QE + +T +L + E AE N KTE A LR +L ++N L + + Q E E + +A EQ + ++ +L E +E L + L +Q E++ LQ +L + EK +++ + ++ A +T+L Q ++A+R + +++++KE L +EK L +L E + ++ A+ + L KE L+ SL+E+QQ S +E LE +Q + + + +I E + L+ E D E + + +++ +L ++E+E L +K A E+++ +L K+++E + Q+E+ L R+K EL E+ IQ +R++ +AE E+E++S+ E + Q L + LER R + +++ ++Q T L++ + + ++ H ++ LQ L K ++ E+LKS L ++++ + Q++ E K+RET++ Y ++KELE T+ L KE R ++ + Q++ RQ +Q+ Q + L Q ++L++EVK+
Sbjct: 23 QVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQAKVLQY-----------------RSWCQELEKRLEATGGPIPQRWENVE--------EPNLD--ELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQ---ELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNH-----------TELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNI-------------AQGSGH------ENSLELDSSIF-------SQFD---------YQD------ADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGE-------VDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLRE----------KWEKE-RSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQE---KLRETQE---------------YNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKE 1112
BLAST of Rootletin-2 vs. Ensembl Celegans
Match: lfi-1 (Lin-5 (Five) Interacting protein [Source:UniProtKB/TrEMBL;Acc:H2L0I3]) HSP 1 Score: 116.316 bits (290), Expect = 2.326e-25 Identity = 242/1075 (22.51%), Postives = 481/1075 (44.74%), Query Frame = 1
Query: 3730 IQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQL---------------SNK---ELREKLKTSEMQK---IDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQ-----VKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLR-KNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKR----------KGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXX------------------------EKGR-------VSSRNSVEF----NFSEDRKRVGRFGD--VNQY--SESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTG-ESYHEEERRGLIKAVDDAENRCTXXX----XXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPT 6711
I + G +K + +++ D D+EI+ + + ++ N LK+ L+ A + D+L + +++ K+R+ Q L EL D K N + + +LE+ Q +NK EL L+ +++ K +++ L L+N+L E+ + L+ + + TEK R+ + ++ + DT+ KL NE+ ++ T + E A + EL K L Q L+ NE+++ + + T D++ ++ E+S+LN +LE + +L S L + E R++ L+ D +R + + NR+ H+ + G+ + P + E GR V+ SV F +FS R G +N + +V D + L+ + I +E ER+++ K+ ET ++Q R ++ N + EE+++ ++SRL SA+T L QEE + + + ER+ + K+ E Q E + ++L E++ +RT ++ H + I+++ D E + R + + + ++ E+E Q+L +++ L + +SK Q ++ D+L +L + E EN + + + + E+Q ++D+L+ Q+ L + + ++ L+ L +V+ + + K + H + +R+ Q++L ++ + K+ +E + ++++ + E +L+ ++ + EK + T+ L L LA LE+ERR+ ++ +KEK +L K ++ LE EK R++ +I ++ L+R ++ +E EN+ L++ +LQ Q+A+ E + RI+ELT++ + E ++ R++ EK ++ RER+HR ++K LE+QI IL+DQL E ++R +++S + NDI + S + N+ S D ++ +G S + P S SN L+ + S++PT
Sbjct: 1207 INSLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAK-----TEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSD-----------------TERNALRNELQK-LSQELKFGNEQIQRKSDEYQTTI----DDLAHSHRVSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSANRVINFHTFVDGGAGYVDGVPGGTSVIGGGPSAQRSGAYDPSSGGVIGSGISGGPGGSDFGREIEIGRGDSDQSDVAYPRSVPFPPSADFSSGRPGAASAGGRVINNLDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTD-----IRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQ----LLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHRNRIKQLEDQIAILRDQLDGERRRRREYVDRS---MVNDIGRLGSNVLGIRNSYGDNSIDAII--------------NGGSRSVGFY--------PRSTFASNPLT-PPLGSSTPT 2219
BLAST of Rootletin-2 vs. Ensembl Celegans
Match: lfi-1 (Lin-5 (Five) Interacting protein [Source:UniProtKB/TrEMBL;Acc:H2L0I3]) HSP 1 Score: 115.546 bits (288), Expect = 3.683e-25 Identity = 242/1075 (22.51%), Postives = 481/1075 (44.74%), Query Frame = 1
Query: 3730 IQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQL---------------SNK---ELREKLKTSEMQK---IDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQ-----VKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLR-KNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKR----------KGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXX------------------------EKGR-------VSSRNSVEF----NFSEDRKRVGRFGD--VNQY--SESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTG-ESYHEEERRGLIKAVDDAENRCTXXX----XXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPT 6711
I + G +K + +++ D D+EI+ + + ++ N LK+ L+ A + D+L + +++ K+R+ Q L EL D K N + + +LE+ Q +NK EL L+ +++ K +++ L L+N+L E+ + L+ + + TEK R+ + ++ + DT+ KL NE+ ++ T + E A + EL K L Q L+ NE+++ + + T D++ ++ E+S+LN +LE + +L S L + E R++ L+ D +R + + NR+ H+ + G+ + P + E GR V+ SV F +FS R G +N + +V D + L+ + I +E ER+++ K+ ET ++Q R ++ N + EE+++ ++SRL SA+T L QEE + + + ER+ + K+ E Q E + ++L E++ +RT ++ H + I+++ D E + R + + + ++ E+E Q+L +++ L + +SK Q ++ D+L +L + E EN + + + + E+Q ++D+L+ Q+ L + + ++ L+ L +V+ + + K + H + +R+ Q++L ++ + K+ +E + ++++ + E +L+ ++ + EK + T+ L L LA LE+ERR+ ++ +KEK +L K ++ LE EK R++ +I ++ L+R ++ +E EN+ L++ +LQ Q+A+ E + RI+ELT++ + E ++ R++ EK ++ RER+HR ++K LE+QI IL+DQL E ++R +++S + NDI + S + N+ S D ++ +G S + P S SN L+ + S++PT
Sbjct: 1280 INSLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAK-----TEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSD-----------------TERNALRNELQK-LSQELKFGNEQIQRKSDEYQTTI----DDLAHSHRVSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSANRVINFHTFVDGGAGYVDGVPGGTSVIGGGPSAQRSGAYDPSSGGVIGSGISGGPGGSDFGREIEIGRGDSDQSDVAYPRSVPFPPSADFSSGRPGAASAGGRVINNLDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTD-----IRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQ----LLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHRNRIKQLEDQIAILRDQLDGERRRRREYVDRS---MVNDIGRLGSNVLGIRNSYGDNSIDAII--------------NGGSRSVGFY--------PRSTFASNPLT-PPLGSSTPT 2292
BLAST of Rootletin-2 vs. Ensembl Celegans
Match: lfi-1 (Lin-5 (Five) Interacting protein [Source:UniProtKB/TrEMBL;Acc:H2L0I3]) HSP 1 Score: 115.546 bits (288), Expect = 3.683e-25 Identity = 242/1075 (22.51%), Postives = 481/1075 (44.74%), Query Frame = 1
Query: 3730 IQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQL---------------SNK---ELREKLKTSEMQK---IDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQ-----VKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLR-KNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKR----------KGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXX------------------------EKGR-------VSSRNSVEF----NFSEDRKRVGRFGD--VNQY--SESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTG-ESYHEEERRGLIKAVDDAENRCTXXX----XXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPT 6711
I + G +K + +++ D D+EI+ + + ++ N LK+ L+ A + D+L + +++ K+R+ Q L EL D K N + + +LE+ Q +NK EL L+ +++ K +++ L L+N+L E+ + L+ + + TEK R+ + ++ + DT+ KL NE+ ++ T + E A + EL K L Q L+ NE+++ + + T D++ ++ E+S+LN +LE + +L S L + E R++ L+ D +R + + NR+ H+ + G+ + P + E GR V+ SV F +FS R G +N + +V D + L+ + I +E ER+++ K+ ET ++Q R ++ N + EE+++ ++SRL SA+T L QEE + + + ER+ + K+ E Q E + ++L E++ +RT ++ H + I+++ D E + R + + + ++ E+E Q+L +++ L + +SK Q ++ D+L +L + E EN + + + + E+Q ++D+L+ Q+ L + + ++ L+ L +V+ + + K + H + +R+ Q++L ++ + K+ +E + ++++ + E +L+ ++ + EK + T+ L L LA LE+ERR+ ++ +KEK +L K ++ LE EK R++ +I ++ L+R ++ +E EN+ L++ +LQ Q+A+ E + RI+ELT++ + E ++ R++ EK ++ RER+HR ++K LE+QI IL+DQL E ++R +++S + NDI + S + N+ S D ++ +G S + P S SN L+ + S++PT
Sbjct: 1280 INSLYGQNQKIKDEWDDFRNDADKEIQKWKTDAYTVRSEAKALETTNTALKAQLQAANDRIDHLTKTVNDHTSKVRDLTSQVRHLEDELADTKGNLVQKEMDLESTQNRLRSLEDQHSTLQSDANKWRGELDAALRENDILKSNNTNMETDLTRLKNRLKSAEDALKELKNSLSHAK-----TEKERLQNAFREKTKQADHLNQLASQFDTKLTKLRNELQDTNDKLITSD-----------------TERNALRNELQK-LSQELKFGNEQIQRKSDEYQTTI----DDLAHSHRVSEDSRLNALQELEARKYEINDLTSRLDSTEQRLATLQQDYIKADSERDILSDALRRFQSSANRVINFHTFVDGGAGYVDGVPGGTSVIGGGPSAQRSGAYDPSSGGVIGSGISGGPGGSDFGREIEIGRGDSDQSDVAYPRSVPFPPSADFSSGRPGAASAGGRVINNLDGTTTVNMNGGFDIANLEGTLQSLLNKIEKLEMERNELRDTLARMKKKTTETHTTINQKETRYRNIEDNLQDAEEERRALESRLQSAKTLLRSQEEALKQRDEERRQMKSKMVAAELQARGKEAQLRHLNEQLKNLRTDLDNAHTD-----IRSLRDKEEQWDSSRFQLETKMRESDSDTNKYQLQIASFESERQILTEKIKELDGALRLSDSKVQDMKDDTDKLRRDLTKAESVENELRKTIDIQSKTSHEYQ----LLKDQLLNTQNELNGANNRKQQLENELLNVRSEVRDYKQRVHDVNNRVSELQRQLQDANTEKNRVEDRFLSVEKVVNTMRTTETDLRQQLETAKNEKRVATKELEDLKRRLAQLENERRNSSQLSDGWKKEKITLLKKIELLENEKRRTDAAIRETALQREAIEKSLNAMERENKELYKNCAQLQQQIAQLEMENGNRILELTNKQREEQERQLIRMRQEKGQIEKVIENRERTHRNRIKQLEDQIAILRDQLDGERRRRREYVDRS---MVNDIGRLGSNVLGIRNSYGDNSIDAII--------------NGGSRSVGFY--------PRSTFASNPLT-PPLGSSTPT 2292
BLAST of Rootletin-2 vs. Ensembl Celegans
Match: epi-1 (Laminin-like protein epi-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21313]) HSP 1 Score: 75.8702 bits (185), Expect = 5.024e-13 Identity = 107/506 (21.15%), Postives = 217/506 (42.89%), Query Frame = 1
Query: 1945 SIADSTCAAVRSALHKRALQ-VQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDS----------NHRE-LDDIQRECERMRHTISMLEEDKLKL---------DKSRMNSYEE------CKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRN---LERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRA-LLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIR--EELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDA----------ERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIY--VLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNE 3327
+I+ +T R A +K+ + ++T +N +N+ +V D ++ + + ++ + N E L ++ + +R R ++ L E L + D + EE S Q EK +T+ +L+ ++ + + + LD+ E Q K E L + +++ LKE S +S N A +L+ +E + +TD L + E K E++ L+DK E M H + N + + E+ K R+ ++K+++ + + E ++ ++ + KD Q+++ ++ NL D L K Q++ A L E E +Q RD + LS V + +K+ E L K+ + QLT +LR+ +A+ + + K LD S+ E Q + +L+A+I+A N+++ K S I + + + + + ++ + A+ + ++LN+
Sbjct: 2159 NISSATIVGARLARNKKEFNDINEITKMLNDEENSFGNVFGDAQDILTNSTQIQNKLVRTKTHSQNSVSSAKNITLNGTEFLQEVMKRAQRARQSVRSLAEIALAIGSSSKAVNVDPRLLKEAEETLMTLEAASADQYPEKAQTVPGKLEEIQKKIQEETEKLDKQKETFEAQKKRAEELAAYLNSAQ---QLLKESKSKADKSNNIAKMLQLTKVENLVAAITDDLERVEAAKGEFQKLNVAIGNITENLKDK---REEMTHAVTTLNETRNDVAEALEAAKKRVRRDEKSVDMQLVNAKAHELHLQATTLRQTFDNNKDNTDQAVE-AANAFSNLTDTLKN---AKAQIDNAYEALSAE--PAFAESVQNARDKPFPDETKEKIDALSKTVSQDLKETEKLKKQ----LEQLTELSEKLRKRKEAVKAGIPKYSKNTLD-SIDEKVQEVEKLKAEIDA---NIEETRAKISEIAGKAEEITEKANSAMEGIRLARRN-SVQLNK 2643
BLAST of Rootletin-2 vs. Ensembl Celegans
Match: epi-1 (Laminin-like protein epi-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21313]) HSP 1 Score: 75.8702 bits (185), Expect = 5.029e-13 Identity = 107/506 (21.15%), Postives = 217/506 (42.89%), Query Frame = 1
Query: 1945 SIADSTCAAVRSALHKRALQ-VQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDS----------NHRE-LDDIQRECERMRHTISMLEEDKLKL---------DKSRMNSYEE------CKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRN---LERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRA-LLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIR--EELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDA----------ERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIY--VLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNE 3327
+I+ +T R A +K+ + ++T +N +N+ +V D ++ + + ++ + N E L ++ + +R R ++ L E L + D + EE S Q EK +T+ +L+ ++ + + + LD+ E Q K E L + +++ LKE S +S N A +L+ +E + +TD L + E K E++ L+DK E M H + N + + E+ K R+ ++K+++ + + E ++ ++ + KD Q+++ ++ NL D L K Q++ A L E E +Q RD + LS V + +K+ E L K+ + QLT +LR+ +A+ + + K LD S+ E Q + +L+A+I+A N+++ K S I + + + + + ++ + A+ + ++LN+
Sbjct: 2159 NISSATIVGARLARNKKEFNDINEITKMLNDEENSFGNVFGDAQDILTNSTQIQNKLVRTKTHSQNSVSSAKNITLNGTEFLQEVMKRAQRARQSVRSLAEIALAIGSSSKAVNVDPRLLKEAEETLMTLEAASADQYPEKAQTVPGKLEEIQKKIQEETEKLDKQKETFEAQKKRAEELAAYLNSAQ---QLLKESKSKADKSNNIAKMLQLTKVENLVAAITDDLERVEAAKGEFQKLNVAIGNITENLKDK---REEMTHAVTTLNETRNDVAEALEAAKKRVRRDEKSVDMQLVNAKAHELHLQATTLRQTFDNNKDNTDQAVE-AANAFSNLTDTLKN---AKAQIDNAYEALSAE--PAFAESVQNARDKPFPDETKEKIDALSKTVSQDLKETEKLKKQ----LEQLTELSEKLRKRKEAVKAGIPKYSKNTLD-SIDEKVQEVEKLKAEIDA---NIEETRAKISEIAGKAEEITEKANSAMEGIRLARRN-SVQLNK 2643
BLAST of Rootletin-2 vs. Ensembl Fly
Match: Root (gene:FBgn0039152 transcript:FBtr0339245) HSP 1 Score: 277.33 bits (708), Expect = 2.327e-74 Identity = 476/2059 (23.12%), Postives = 961/2059 (46.67%), Query Frame = 1
Query: 685 QTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAE-------------------TDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIID-TDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVS--IADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAE-------RLSAAVQKSMKD---KEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQ-------RERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEA----TKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRN---SVEFNFSEDRKRVGRFGDVNQYSESVIPGS--DLDPEAVRIALRDITQHIVSIERERDDMEIK---AKNSALKSDETSVQLDQALQRINQLQKNFGE----VEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQE---------------IEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERR---DIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRR--LEDENEVLHRQVQKLQNQLAEAE----QCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRE---LNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNC 6615
Q +LR++L D+ Y+R+L Q QA L+ RLQ K++Q R +E+ + K + + T + + + ++ L + T + +L+EE + ++ + LR QL+E+ N+ LT D+Q+L+ + + L+ EL K+ ++K++E F + E NR+ +W VV KR F +++++ + ++ ++ I C D N N Q Q + + ++ +++ + Q Q+ +L Q+ ES E+ ++++ L +L N + D +A D + ++ ++R+IAQ V+ D + D +++ TG + + +H R + ++ RN + S A+ T +AV++ALHK L + D+ K + + K QL+ SE ++ L + +L + DS++ +L ++ +E E ++ + + K + + R + ++ D EK++ +LQ+ +++ ++ + ++ ++R K+ ++ + E +SSRL+EE SL+E LNR L +++LEQ+ + +N E K++ E +K E+ L++K +L + + E + + + + E+ +L + E +++EL ++ + EL + ++ ++ E + +L+ + ++G + + R++ AL+ EL++ R+ E RL+ +++ +KD K+V+ IDL + T H L E + L+ EKE L+ L+++ ++ E + LE +LQ+ + + + RLQ E + +K + K L +E ++N+ + + E ++ + ++ + Q+ + L+ + + E+L + + T+Q ++ ++ L+ AE KQ A+ + ++K ++ E++ ++ L+T + L+R+R E R ++ + I ++ + R + E+ I + I+ + L ++ R +EELK +++ E+ ++ +L +++ K +E E + LR+EL D +R + E + SNKELR+ +K E K + R +++ K+S LE+ K L+ E L++TE ++L ++Q++K E + LQ ++ + + A++E +K+++ + EA T++EL + Q N + E +++E+ Q +E K LE+ K NLE L +EL + L E RI L+ Q++ ++ ++ E +L+++ LR++ G Q+ G V+ + S FS R GD + S S P D+DP+ VR +R++ + +ERE+DD + + AK + + ++ D L ++ + +N E +E D+K ++S+ Q ++E+ HRN+ E + L +++ + E QLA E +ER++K R S + E+R L + + E R ++LEL R +EG+L RL+M +K+ + + +R++ + ++ LE + +L+ T+D+L L ++ E + ++ L LSE Q+ +DKL +Q +L ++E+++R+L ERL+S + NL+E + +D + Q+++ + E ++ +E +++ I QE E+EL ++ S EK+ L +L +L + LE +R+ + + EK + + E + NR + + F+ +E E L +V++L+ LAE E +C A+ M +++ + + + DR +SA EK L RE+SHRQ+V LE QI++L++QL+QE K+R+ L +K+NR +++ ++S L + N+S+ D L E E RR+ +S S ++C
Sbjct: 94 QNQELRQRLADESHSYRRRLDTYKQAQHNQANLVSRLQSKIQQYRQRCSDLEERMHETIKPTAGVGPKLTTGPTNQVLCSTSLTLGQSSLPCSSSLDSPPPSCSRDYVDDVLVTGGGAGAAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQAFKDYYNSEHNRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEIN---------CVGKDINGSNATVAFAVQ---------QAKRAADDELKQSQRSNDELQNQLATLKVQY-------ESARHEIMERDQRLL---ELMNQLKKLEDRCAQAESQAALASRYSDEIERLNNSMREIAQAVVQDAENADREA--------DAEVTGGV-----MQHMHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVV----IDLHEKDT---HRLNE---LLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKI-------ANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQ----NNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGI--QV---------------------DGSVNLSHRLLSPSRRFSPSRS----CGDYDNRSTSQCPDGPIDVDPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRK---MKISAIQA---LEEKLKHRND-ECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLR----IAKWNQESGGDKDLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKSKFSGGNAYDRAEKSNSFYGGAAESGEFDSNRYD--VGGGNAGGGSFNCGLDHSVIEQETRDLRLKVRRLETLLAEKESELARCKAR--MNDSAKCHDGL--DGDRYRSAQMHAEKLLDAREQSHRQQVLRLENQISMLREQLAQEAKRRQQYILRSSKANREMQH----LRSTLGDSLRNVSQHPVDPHLLESESRRLDSAVSMSLPPSSC 2042
BLAST of Rootletin-2 vs. Ensembl Fly
Match: Root (gene:FBgn0039152 transcript:FBtr0339244) HSP 1 Score: 277.33 bits (708), Expect = 2.327e-74 Identity = 476/2059 (23.12%), Postives = 961/2059 (46.67%), Query Frame = 1
Query: 685 QTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAE-------------------TDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIID-TDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVS--IADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAE-------RLSAAVQKSMKD---KEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQ-------RERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEA----TKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRN---SVEFNFSEDRKRVGRFGDVNQYSESVIPGS--DLDPEAVRIALRDITQHIVSIERERDDMEIK---AKNSALKSDETSVQLDQALQRINQLQKNFGE----VEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQE---------------IEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERR---DIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRR--LEDENEVLHRQVQKLQNQLAEAE----QCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRE---LNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNC 6615
Q +LR++L D+ Y+R+L Q QA L+ RLQ K++Q R +E+ + K + + T + + + ++ L + T + +L+EE + ++ + LR QL+E+ N+ LT D+Q+L+ + + L+ EL K+ ++K++E F + E NR+ +W VV KR F +++++ + ++ ++ I C D N N Q Q + + ++ +++ + Q Q+ +L Q+ ES E+ ++++ L +L N + D +A D + ++ ++R+IAQ V+ D + D +++ TG + + +H R + ++ RN + S A+ T +AV++ALHK L + D+ K + + K QL+ SE ++ L + +L + DS++ +L ++ +E E ++ + + K + + R + ++ D EK++ +LQ+ +++ ++ + ++ ++R K+ ++ + E +SSRL+EE SL+E LNR L +++LEQ+ + +N E K++ E +K E+ L++K +L + + E + + + + E+ +L + E +++EL ++ + EL + ++ ++ E + +L+ + ++G + + R++ AL+ EL++ R+ E RL+ +++ +KD K+V+ IDL + T H L E + L+ EKE L+ L+++ ++ E + LE +LQ+ + + + RLQ E + +K + K L +E ++N+ + + E ++ + ++ + Q+ + L+ + + E+L + + T+Q ++ ++ L+ AE KQ A+ + ++K ++ E++ ++ L+T + L+R+R E R ++ + I ++ + R + E+ I + I+ + L ++ R +EELK +++ E+ ++ +L +++ K +E E + LR+EL D +R + E + SNKELR+ +K E K + R +++ K+S LE+ K L+ E L++TE ++L ++Q++K E + LQ ++ + + A++E +K+++ + EA T++EL + Q N + E +++E+ Q +E K LE+ K NLE L +EL + L E RI L+ Q++ ++ ++ E +L+++ LR++ G Q+ G V+ + S FS R GD + S S P D+DP+ VR +R++ + +ERE+DD + + AK + + ++ D L ++ + +N E +E D+K ++S+ Q ++E+ HRN+ E + L +++ + E QLA E +ER++K R S + E+R L + + E R ++LEL R +EG+L RL+M +K+ + + +R++ + ++ LE + +L+ T+D+L L ++ E + ++ L LSE Q+ +DKL +Q +L ++E+++R+L ERL+S + NL+E + +D + Q+++ + E ++ +E +++ I QE E+EL ++ S EK+ L +L +L + LE +R+ + + EK + + E + NR + + F+ +E E L +V++L+ LAE E +C A+ M +++ + + + DR +SA EK L RE+SHRQ+V LE QI++L++QL+QE K+R+ L +K+NR +++ ++S L + N+S+ D L E E RR+ +S S ++C
Sbjct: 94 QNQELRQRLADESHSYRRRLDTYKQAQHNQANLVSRLQSKIQQYRQRCSDLEERMHETIKPTAGVGPKLTTGPTNQVLCSTSLTLGQSSLPCSSSLDSPPPSCSRDYVDDVLVTGGGAGAAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQAFKDYYNSEHNRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEIN---------CVGKDINGSNATVAFAVQ---------QAKRAADDELKQSQRSNDELQNQLATLKVQY-------ESARHEIMERDQRLL---ELMNQLKKLEDRCAQAESQAALASRYSDEIERLNNSMREIAQAVVQDAENADREA--------DAEVTGGV-----MQHMHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVV----IDLHEKDT---HRLNE---LLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKI-------ANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQ----NNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGI--QV---------------------DGSVNLSHRLLSPSRRFSPSRS----CGDYDNRSTSQCPDGPIDVDPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRK---MKISAIQA---LEEKLKHRND-ECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLR----IAKWNQESGGDKDLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKSKFSGGNAYDRAEKSNSFYGGAAESGEFDSNRYD--VGGGNAGGGSFNCGLDHSVIEQETRDLRLKVRRLETLLAEKESELARCKAR--MNDSAKCHDGL--DGDRYRSAQMHAEKLLDAREQSHRQQVLRLENQISMLREQLAQEAKRRQQYILRSSKANREMQH----LRSTLGDSLRNVSQHPVDPHLLESESRRLDSAVSMSLPPSSC 2042
BLAST of Rootletin-2 vs. Ensembl Fly
Match: Root (gene:FBgn0039152 transcript:FBtr0304161) HSP 1 Score: 277.33 bits (708), Expect = 2.327e-74 Identity = 476/2059 (23.12%), Postives = 961/2059 (46.67%), Query Frame = 1
Query: 685 QTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAE-------------------TDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIID-TDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVS--IADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAE-------RLSAAVQKSMKD---KEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQ-------RERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEA----TKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRN---SVEFNFSEDRKRVGRFGDVNQYSESVIPGS--DLDPEAVRIALRDITQHIVSIERERDDMEIK---AKNSALKSDETSVQLDQALQRINQLQKNFGE----VEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQE---------------IEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERR---DIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRR--LEDENEVLHRQVQKLQNQLAEAE----QCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRE---LNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNC 6615
Q +LR++L D+ Y+R+L Q QA L+ RLQ K++Q R +E+ + K + + T + + + ++ L + T + +L+EE + ++ + LR QL+E+ N+ LT D+Q+L+ + + L+ EL K+ ++K++E F + E NR+ +W VV KR F +++++ + ++ ++ I C D N N Q Q + + ++ +++ + Q Q+ +L Q+ ES E+ ++++ L +L N + D +A D + ++ ++R+IAQ V+ D + D +++ TG + + +H R + ++ RN + S A+ T +AV++ALHK L + D+ K + + K QL+ SE ++ L + +L + DS++ +L ++ +E E ++ + + K + + R + ++ D EK++ +LQ+ +++ ++ + ++ ++R K+ ++ + E +SSRL+EE SL+E LNR L +++LEQ+ + +N E K++ E +K E+ L++K +L + + E + + + + E+ +L + E +++EL ++ + EL + ++ ++ E + +L+ + ++G + + R++ AL+ EL++ R+ E RL+ +++ +KD K+V+ IDL + T H L E + L+ EKE L+ L+++ ++ E + LE +LQ+ + + + RLQ E + +K + K L +E ++N+ + + E ++ + ++ + Q+ + L+ + + E+L + + T+Q ++ ++ L+ AE KQ A+ + ++K ++ E++ ++ L+T + L+R+R E R ++ + I ++ + R + E+ I + I+ + L ++ R +EELK +++ E+ ++ +L +++ K +E E + LR+EL D +R + E + SNKELR+ +K E K + R +++ K+S LE+ K L+ E L++TE ++L ++Q++K E + LQ ++ + + A++E +K+++ + EA T++EL + Q N + E +++E+ Q +E K LE+ K NLE L +EL + L E RI L+ Q++ ++ ++ E +L+++ LR++ G Q+ G V+ + S FS R GD + S S P D+DP+ VR +R++ + +ERE+DD + + AK + + ++ D L ++ + +N E +E D+K ++S+ Q ++E+ HRN+ E + L +++ + E QLA E +ER++K R S + E+R L + + E R ++LEL R +EG+L RL+M +K+ + + +R++ + ++ LE + +L+ T+D+L L ++ E + ++ L LSE Q+ +DKL +Q +L ++E+++R+L ERL+S + NL+E + +D + Q+++ + E ++ +E +++ I QE E+EL ++ S EK+ L +L +L + LE +R+ + + EK + + E + NR + + F+ +E E L +V++L+ LAE E +C A+ M +++ + + + DR +SA EK L RE+SHRQ+V LE QI++L++QL+QE K+R+ L +K+NR +++ ++S L + N+S+ D L E E RR+ +S S ++C
Sbjct: 94 QNQELRQRLADESHSYRRRLDTYKQAQHNQANLVSRLQSKIQQYRQRCSDLEERMHETIKPTAGVGPKLTTGPTNQVLCSTSLTLGQSSLPCSSSLDSPPPSCSRDYVDDVLVTGGGAGAAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQAFKDYYNSEHNRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEIN---------CVGKDINGSNATVAFAVQ---------QAKRAADDELKQSQRSNDELQNQLATLKVQY-------ESARHEIMERDQRLL---ELMNQLKKLEDRCAQAESQAALASRYSDEIERLNNSMREIAQAVVQDAENADREA--------DAEVTGGV-----MQHMHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVV----IDLHEKDT---HRLNE---LLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKI-------ANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQ----NNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGI--QV---------------------DGSVNLSHRLLSPSRRFSPSRS----CGDYDNRSTSQCPDGPIDVDPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRK---MKISAIQA---LEEKLKHRND-ECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLR----IAKWNQESGGDKDLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKSKFSGGNAYDRAEKSNSFYGGAAESGEFDSNRYD--VGGGNAGGGSFNCGLDHSVIEQETRDLRLKVRRLETLLAEKESELARCKAR--MNDSAKCHDGL--DGDRYRSAQMHAEKLLDAREQSHRQQVLRLENQISMLREQLAQEAKRRQQYILRSSKANREMQH----LRSTLGDSLRNVSQHPVDPHLLESESRRLDSAVSMSLPPSSC 2042
BLAST of Rootletin-2 vs. Ensembl Zebrafish
Match: crocc2 (ciliary rootlet coiled-coil, rootletin family member 2 [Source:ZFIN;Acc:ZDB-GENE-131121-625]) HSP 1 Score: 496.123 bits (1276), Expect = 4.201e-143 Identity = 552/1919 (28.76%), Postives = 1014/1919 (52.84%), Query Frame = 1
Query: 715 DDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDD-EATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATR-QLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDK--SRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKD--YKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSS----RNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRE 6441
++ R Y+ KL A + Q +QA+L+++LQ KL Q + R G L QQ + SE +L+ Q+ +D + + L+ E + ++D+++ + L +EQ + L Q+ ALLR+QL++A NQ LTE +Q+ + E EQ+D + + E SR EQ R++SLW V + F +++ +R L L+ ++ LR+AC NL+ + + T N S LE L E + + ++ + L+ + + + + L + ++KE L L N M + ++D A R L + ++HQ L +I Q+V +V + +S H + S ++GS+ ++ + P+ AV+ AL +R Q +DL + + +++ +++KQL E++ R LEK+ EL+ E R +D R+ ER R+++ ++ +K +L++ S M EC +Q E L++ + ++QR ++ L +DL+R L R+ E ER ++E E++ S +++E+ +LKE+L++ L+KEVLE EN L +L+K E AE E+ K ++E+A L+D ++ +++ L K+ E ++ Q E+EK L ++ E E+ REEL R++ E +L K L S ++++ L E + L EK ++ + +++ A+ +L R+ E +A +QK+ K+++ LA++K +L QLT+ + + + A + L+ E+E L+ SL + Q+ S LEA + L+ L++ + E +Q E + ++ + + K++L++KL ++E+ ++L + +++ +E + +E + E +E+ + Q + E +LR + R ++L +++ +Q+ + LL+AE KQ ++ E EK ++ E+I L + + + +R R + + +QD++T +L R +FE+ + ++L +EL Q +E E LK L EE+RD R++L E+ ++RE ++ RRE +D KR + +E E I SN ELR LK E + ++R ++ +L++LEE K LQ+EV R N+++ EK+R+ RREL+ELR QVK L+ + + E+S +Q R+ +E +E E R+E F L+QKV+ESEA KE K+ R ELEE + +EK +Q D L+D K EE LE L+ + E +++ E R LE Q+ D KR+ E+RL ++S LR+ +G R+ R E+GR S R+ V+ D VG V S S +LD +AV++ L Q + ++ERD+ + + + + + +++ I L+++ E+EE K+ + L Q +L++++E + R E + + + +++ K+++ +ETE K LQ+++++ + E E ERR L + + + R +L+L RRGLEGELQR ++ + E E L++R++ L +++ D E +A L++ +RL+ LA E +E+ KDK+ L SL++ + + +D+ VQLQ L++SEH+++++QE+L+ + L+ ++ QNH L +R+++ Q+ E E + E++ + + L + + QRQ+ EQE Q + + L E++ +L + L+ E+ D+E+ ++ K+++SLK+TL+K+E + + E I +R + ++ R LE+E ++ LQ+Q++ E H+QR++E+++R K E+ E +R++ + TE+ L+ RE++HRQ+V LEEQ++ LK+QL QE+K+R+
Sbjct: 126 EEGRSYRLKLQAYQESQHRQAQLVQKLQAKLLQYKKRCG---NLEQQVLEKTSESEKLRLSLQS-------HLDSSAHRLQRFEQEHSLDVQNKLALLDDEQKRCSGLSQVNALLREQLEQANETNQALTESLQKA-------RDEAEQRDTRLRRELEMNTSRN-SREQVRVRSLWRQVAFLRSSFTQLRAFADRSLSDLQAEYAATSHRLRVACLNLEASKSQSCT-------TASNGVSALETQLRDKLREAMQLQARFDAEKVELSSRILELGEMVKQLRAQNSEKESNLIALRSNLNKMETN------RSEDRAERDALRSEISSLHQILHNINQVVSGEVSR-------------------------DCSSKHEH-----------SFISAGSISSSQ---REGPL-------IAVQKALLQRQTQTEDLQACLEASQEQVVTLQKQLHVEEDKTRTLEKRLQELQQENQLLERAEEDSTRDAERYRNSLGIITSEKGELERQLSAMQQQLECTQTEQ--EGLRSSSLDVQRQRDLLRQQREDLERQLARERSESERGRHTLEQLEARYSDVRKELVTLKEALSQLSLQKEVLEDENRSLAQALSKAEAQNAEQELALTKLRSEDAGLQDSLAKMGALSEGLAKDKVELNRLLLQAEAEKAELGERRREAELERMAAREELARLQQELLDLTAEKRALEASHNYLQEAKMTLDAEYNLLQREKSSVQEQHAQASKQKQAVQEQLNACHREMELSAALLQKTYKERDELARDKANLTVQLTSEQRKSKALAQDLAALRAERESLESSLLDRQELASSLEAIRDRLDGENASLQQANKSLTRELSSVQSELEQQMSRALQEKQALELKLAQAERNAQEMLITTQQSHQEQLHTERKHKERMHAELCAQREQAESQLRAECKELRIQSRRVLQQLQEDLAKLQQHCTESLLQAESHKQQVLSEKEAEKATLIERIITLERDMEAAALEKDRMRRDFLSKQEQDKDTASGLQAELHNLRSRFEESLSSREVSERSLNEQIRELSTQWQGAHQEAERLKRELSEVEESRDTGRKELIEAHRELRECLQDKDEQRREGLDLKRALGDAVREKEAINTSNHELRTALKRVEFENNSLKRVGEEKDQRLTVLEECKSSLQQEVLKLRTNMRELEKSRLQARRELQELRRQVKTLEGQCTQQGQELSDMQARLTQEEQREEEMRKETFTLRQKVLESEAGKEAALKEAAGLQRHIAELEEA-HQQEKELQQQRDASLQDSQLKQREEVA-RLEGALQESQAQLREFGLSVNLAEARAQGLEEQLAQNDAKRRDLEHRLNVLNSTLRRTLGSRR--------------GRQSPTPGERGRSPSPWRTRSPVKGEIISDETGVGGL-PVCSLSPSRREDGELDLDAVQMLLHSFQQELRDTQKERDESHAQVHSLSKQVENLQANQERSNTCIQMLRQSIRELEEGKRELAKHLEGMQASLVLRDEAVQRGETQNRIMNEELAKMKKSQLIIETEAKALQDKLERSQASEESLEAERRRLKETCEAVDARAARLDLKRRGLEGELQRAQLRTTEMEAEASSLQERLNNLRRELGDSEERAALLKVECERLATALAHKELQESQLKDKLQALTASLTDSNASAGTARDQAVQLQRALSASEHNQKMVQEKLDKTREALTHSRKQNHDLSERLQSLQRSQEECELKVSELDKQTRVLQETVRQRQQAEQEAQESCLLLQEQNSQLQEQVATLQTTAHRLQGEKSDLERTLLRLGKDRSSLKRTLEKVEHNRQKKEVEILHGEREREQQEQKIRNLEEELNETQAEIHTLQSQISILEHTHSQRLLEVSARHKQELDLESERMRDSQQQTERALEAREKAHRQRVHCLEEQVSTLKEQLEQEMKRRQ 1948
BLAST of Rootletin-2 vs. Ensembl Zebrafish
Match: crocc2 (ciliary rootlet coiled-coil, rootletin family member 2 [Source:ZFIN;Acc:ZDB-GENE-131121-625]) HSP 1 Score: 225.328 bits (573), Expect = 1.910e-59 Identity = 282/984 (28.66%), Postives = 514/984 (52.24%), Query Frame = 1
Query: 2629 SMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKD--YKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSS----RNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLS 5562
+++ L K+ E ++ Q E+EK L ++ E E+ REEL R++ E +L K L S ++++ L E + L EK ++ + +++ A+ +L R+ E +A +QK+ K+++ LA++K +L QLT+ + + + A + L+ E+E L+ SL + Q+ S LEA + L+ L++ + E +Q E + ++ + + K++L++KL ++E+ ++L + +++ +E + +E + E +E+ + Q + E +LR + R ++L +++ +Q+ + LL+AE KQ ++ E EK ++ E+I L + + + +R R + + +QD++T +L R +FE+ + ++L +EL Q +E E LK L EE+RD R++L E+ ++RE ++ RRE +D KR + +E E I SN ELR LK E + ++R ++ +L++LEE K LQ+EV R N+++ EK+R+ RREL+ELR QVK L+ + + E+S +Q R+ +E +E E R+E F L+QKV+ESEA KE K+ R ELEE + +EK +Q D L+D K EE LE L+ + E +++ E R LE Q+ D KR+ E+RL ++S LR+ +G R+ R E+GR S R+ V+ D VG V S S +LD +AV++ L Q + ++ERD+ + + + + + +++ I L+++ E+EE K+ + L Q +L++++E + R E + + + +++ K+++ +ETE K LQ+++++ + E E ERR L + + + R +L+L RRGLEGELQR ++ + E E L++R++ L +++ D E +A L++ + LS
Sbjct: 3 ALSEGLAKDKVELNRLLLQAEAEKAELGERRREAELERMAAREELARLQQELLDLTAEKRALEASHNYLQEAKMTLDAEYNLLQREKSSVQEQHAQASKQKQAVQEQLNACHREMELSAALLQKTYKERDELARDKANLTVQLTSEQRKSKALAQDLAALRAERESLESSLLDRQELASSLEAIRDRLDGENASLQQANKSLTRELSSVQSELEQQMSRALQEKQALELKLAQAERNAQEMLITTQQSHQEQLHTERKHKERMHAELCAQREQAESQLRAECKELRIQSRRVLQQLQEDLAKLQQHCTESLLQAESHKQQVLSEKEAEKATLIERIITLERDMEAAALEKDRMRRDFLSKQEQDKDTASGLQAELHNLRSRFEESLSSREVSERSLNEQIRELSTQWQGAHQEAERLKRELSEVEESRDTGRKELIEAHRELRECLQDKDEQRREGLDLKRALGDAVREKEAINTSNHELRTALKRVEFENNSLKRVGEEKDQRLTVLEECKSSLQQEVLKLRTNMRELEKSRLQARRELQELRRQVKTLEGQCTQQGQELSDMQARLTQEEQREEEMRKETFTLRQKVLESEAGKEAALKEAAGLQRHIAELEEA-HQQEKELQQQRDASLQDSQLKQREEVA-RLEGALQESQAQLREFGLSVNLAEARAQGLEEQLAQNDAKRRDLEHRLNVLNSTLRRTLGSRR--------------GRQSPTPGERGRSPSPWRTRSPVKGEIISDETGVGGL-PVCSLSPSRREDGELDLDAVQMLLHSFQQELRDTQKERDESHAQVHSLSKQVENLQANQERSNTCIQMLRQSIRELEEGKRELAKHLEGMQASLVLRDEAVQRGETQNRIMNEELAKMKKSQLIIETEAKALQDKLERSQASEESLEAERRRLKETCEAVDARAARLDLKRRGLEGELQRAQLRTTEMEAEASSLQERLNNLRRELGDSEERAALLKVCVCVLS 969
BLAST of Rootletin-2 vs. Ensembl Zebrafish
Match: si:dkey-230p4.1 (si:dkey-230p4.1 [Source:ZFIN;Acc:ZDB-GENE-081104-380]) HSP 1 Score: 85.1149 bits (209), Expect = 1.410e-17 Identity = 68/269 (25.28%), Postives = 127/269 (47.21%), Query Frame = 1
Query: 487 ENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSN 1293
E A L+ L +++EL + ER+ L + A+ ++L++T R LD++ RE+++KL + + +QA LI +LQ K+ R + L QQ + + + R D LES + L+EEQ +S+ L +++ALLR QL ++T AN+ L +D+++L+ + S E+ QK++DW+ ++ + ++ E +R+ +LW VV +RQ + +K++
Sbjct: 12 ERAELRAELSRLQDELAESRAEREELDSRAQALTDRLSQTLDPSLSSSVR------------------------LDEEQREWRKKLREGREREARQALLIHKLQHKVLDYRAR---CQALEQQA------VGEERELRIRERILRDERSDT---------------LESTLIRLEEEQQRSLGLSEVSALLRSQLSQSTEANEALRDDLRKLTADWSKAVEEVVQKEIDWQKEKEVLTGYIGKEHSRLMTLWGRVVTLRRQCHSLKTAT 232
BLAST of Rootletin-2 vs. Ensembl Zebrafish
Match: si:dkey-230p4.1 (si:dkey-230p4.1 [Source:ZFIN;Acc:ZDB-GENE-081104-380]) HSP 1 Score: 90.5077 bits (223), Expect = 2.721e-17 Identity = 71/280 (25.36%), Postives = 135/280 (48.21%), Query Frame = 1
Query: 487 ENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNI 1326
E A L+ L +++EL + ER+ L + A+ ++L++T R LD++ RE+++KL + + +QA LI +LQ K+ R + L QQ + + + R D LES + L+EEQ +S+ L +++ALLR QL ++T AN+ L +D+++L+ + S E+ QK++DW+ ++ + ++ E +R+ +LW VV +RQ + +K++ ++DL +L+ +
Sbjct: 12 ERAELRAELSRLQDELAESRAEREELDSRAQALTDRLSQTLDPSLSSSVR------------------------LDEEQREWRKKLREGREREARQALLIHKLQHKVLDYRAR---CQALEQQA------VGEERELRIRERILRDERSDT---------------LESTLIRLEEEQQRSLGLSEVSALLRSQLSQSTEANEALRDDLRKLTADWSKAVEEVVQKEIDWQKEKEVLTGYIGKEHSRLMTLWGRVVTLRRQCHSLKTATDKDLWELKADF 243
BLAST of Rootletin-2 vs. Ensembl Xenopus
Match: pgm2 (phosphoglucomutase 2 [Source:Xenbase;Acc:XB-GENE-1006723]) HSP 1 Score: 535.798 bits (1379), Expect = 3.753e-156 Identity = 597/2072 (28.81%), Postives = 1095/2072 (52.85%), Query Frame = 1
Query: 307 PQKMPEVVK---DIILRDFGDTDEDE-------DSIKDLRMPKPN------SQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGR-NGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLII----DTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKG----QLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRM--KATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRE 6441
P K+ V++ D++L + G + ED + +D P P +QN + S + + L+ L+ EN +L+D L +E+ L ++ER++L+I+ A+NEKL + + + + G+ + LR++ ++ YKRKL+A + Q +QA+L++RLQ K+ Q + R L ++L ++ S+ SE RL L R+D AE L + + +++L + + L EEQ +S SL Q+ LR+Q+++ N+ LTE+++RL+ + +L+Q++ +W+ + ++ +L E + I +LW + QF D++ ER L +++ +I +S++ + AC NLD+N RLSQ + ++LE L + + ++Q+ + LN + ++ E L +E + KEK + I N T Q + + D++ Q L I Q+ DV SP D ES TG + N + +SVSP F+S + R R +SP ++ AV++ L + + ++L S++ +A+++ KKQ E + E EL+ E + L+ +++E +R +++I +L +K +++S ++ + + E+LK +N EL R +E L + ++L+R +R KE+ER + E E K S LK+++ +++ESL++ LE++VL+ E + +L+K E +AE E+ N+ +E A L D ++ ++N L ++ +I Q E E+ L +++A E ++E+ +E+E +L + GL + + E+ ++ +++L ++ E+G QL AN +Q L +L ++RR+ + +A+Q++ + E L + +L QL E E +E+ + L+ +KE L+ +LYE+Q+ +QLE + E LE + L + + E QR E + L L + K +++++L ++E+ L ++ + ++ ++RL E+E LR + K++ + ++E +DL K++L+ EI+ +Q ER++ LL+ E KQ A+ L E EK S+ EK+ L ++ ++ER R E +I+ +QD+ ++ +LK + FE H +E KNL+ K+L ++ +E EEL++ L++AE++RD+LR+D+ E +RE E+ E R+E ++ +R+ ++ +E ET+Q SN ELR +K E ++ +Q +++ Q ++S+L+E K ++E R L+D E++ ++ RR+L+ELR QVK L E + EV+ LQ R+ +E KE ++RRE+ L+Q++ ESE+ +E +++ + LE +EK +Q E + L+E+ +L+ QL+ + L E R+ LE +++ R+ AE+ + ++S LR+ IG R + R S + G S SP +GRV+ + S DR R P +L+PE V+ ALRD Q + +RERD+ I+ + + +++ ++ + +LQ+ +++E ++G + RL +A T + + ++ + +E ER++ +++ +LE L E E + Q+R+ + R E+ E E +GL + ++ +ENR T+LEL +R LEGEL+R +M ++E E Q L++R L +Q+ D E + SLQ + RL++ L+R ++ E ++K L +L E ++Q+ + +LQ L ++E DRRVLQERL+SV+ LS++K N L + + Q E M R+ + + + + + I Q++E EQ + +E + E+L L A +E ++++I+ + EK N+L+ TLDK+++E+ R E + +++ + L + RQ Q LQ Q+ E E+ H QR+ME++ R + E+ SE +R S E TL+ RERSHRQ+V+ LEEQIN L++QL QE+++R+
Sbjct: 8 PMKLETVIQHLEDVVL-NPGSSVEDRALSVRSGEGERDALTPVPARIREIVTQNLREDSAYMSPESHLN--LSLQEENRSLQDELLRMEDLLSLTRSEREDLSIRNQALNEKLEQ-YQSHRSGE----------------TEAVLDLRQRFHEEEMAYKRKLSAYQEGQQRQAQLVQRLQDKVLQYKRRCRELEQQLLEKTSE--SEQQRLA---------LQARLDSAETKLNRMDQNHSLELNNALTRLDEEQQRSSSLAQVNNTLREQMEQLKTTNEKLTEEIKRLTSDLHKSHEDLDQREAEWRKERQNYTFYLSNEHSGILTLWRKAAALRSQFLDMRGITERGLAEIKTDISRSSRRMHTACLNLDSNL--RLSQSAAGASL---HTARLEQQLRDKVRQMMQLQSQWDAEKVELNSRVSELSLQTEKLVRENSKKEK----------------EKQILENSGCDTLQELEGVREECDSLQQVLSSITQMCQTDV-----SP---DPTCVES--TG----VSATNEM--RQSVSPLFV-----FSSSPIRRRSPTRMRSPQR-SELALKAVQNVLQRHQDREKELHSELAAARDSLEQTKKQ---QEKNQHVSEAHTEELKKENKEINTILESVKQELQRCQNSIELLTREKEDMEESLQTIKQKAEGSLLETERLKAVNAELLRQREALEEQKEELNRERDRSQKELERGQRIQEQLEEKVSILKKDLVTVRESLSQTALERDVLQGEKEAVASALSKAESSRAELELALNQMHSERATLTDSLAKMGALNEGLAQDKVALNRVILQLEGERAALHEDRRAGEANCAALKEQQEALEHEVSQLQADRVGLERRCREAEEKHKRQEEQLLGVHKERGKLQDQLAQANTLVQ----TLQDQLKESRREMDLQGSALQRAAQRMEELTSQNAELGVQLAALEDERQEHEEEFAQLRAQKESLESTLYETQRRAAQLEDRREQLEGEIHTLTLVKQSLQVETQRQALEAEEALAGLRQQKVTVELQLAQTEQAAQLSLSNQSQQHQDTVDRLKREKESLRLTMIADKQDSVQRLEKEKEDLLFDRENVKQKLSAEILRLQEEREESLLKVESEKQKALLLKETEKNSLSEKLMNTQRELSDTKMEMERCRREAQIKQEQDKTSLDNVLSELKALQSDFEDAVSAHSKENKNLRDRMKQLSQERESLNKEVEELRTQLRLAEDSRDSLRRDIIEVQRLLREKEEICESQRKETLELRRDVGDLTRERETLQKSNTELRACIKKIESERSSLQVAMEEKQQRISVLQEGKSCAEREAAHLRATLRDVERSHIEARRQLQELRRQVKTLGGESSQKEQEVAELQARIQQEEQKEQQSRRESLELRQRITESESEREAARREILTLQQHLSALESSSRQREKELEQRLSESRAGEQRLQEACKSLQEQLQRCTSESGDSRLQLGAFEARVRALEAELSKSQASRREAESHVNGLYSALRRTIGVRGRSPSPRRALSSTKGLDSSHGSPMEGRVTPSSR---GVSPDRSRS--------------PYPELEPELVKQALRDFMQELRDTQRERDEAGIQVLSLRRQLEDSINSCERLQSQQQKLQRQLADLQEGQRGTEERLGTAHTEMRLLQDNLRHSEAERQASGERIMELEHSLRICEDENRDFQDRLSRARNAENRQELECKGLREVLEASENRGTELELRKRSLEGELERTRMSLAEREAEVQTLQERAHHLQEQLKDSEDREASLQTEVQRLNLALSRAQDGERQLQEKSQGLTQALGEATAGRGNLQEDVSRLQGALTAAEQDRRVLQERLDSVRQALSDSKRHNLRLSQTIQEQQQQLEEMHLNCRELQAQLQDLQQTLIKQQQREEEQ------GAALLE---VQEKLKMLQGDKAQVELDKQEIQHSAVLLEKGNNTLRATLDKVKREQLRIEGEAQRLSVEKEQLSHSVISLRKDLAEAQRQNQYLQEQMTEMERSHTQRLMEVSLRHRQELDSESNRAHSIQQQVESTLESRERSHRQRVRGLEEQINSLQEQLEQEVRRRQ 1972
BLAST of Rootletin-2 vs. Ensembl Xenopus
Match: pgm2 (phosphoglucomutase 2 [Source:Xenbase;Acc:XB-GENE-1006723]) HSP 1 Score: 533.102 bits (1372), Expect = 2.514e-155 Identity = 582/1999 (29.11%), Postives = 1066/1999 (53.33%), Query Frame = 1
Query: 478 LKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGR-NGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLII----DTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKG----QLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRM--KATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRE 6441
L+ EN +L+D L +E+ L ++ER++L+I+ A+NEKL + + + + G+ + LR++ ++ YKRKL+A + Q +QA+L++RLQ K+ Q + R L ++L ++ S+ SE RL L R+D AE L + + +++L + + L EEQ +S SL Q+ LR+Q+++ N+ LTE+++RL+ + +L+Q++ +W+ + ++ +L E + I +LW + QF D++ ER L +++ +I +S++ + AC NLD+N RLSQ + ++LE L + + ++Q+ + LN + ++ E L +E + KEK + I N T Q + + D++ Q L I Q+ DV SP D ES TG + N + +SVSP F+S + R R +SP ++ AV++ L + + ++L S++ +A+++ KKQ E + E EL+ E + L+ +++E +R +++I +L +K +++S ++ + + E+LK +N EL R +E L + ++L+R +R KE+ER + E E K S LK+++ +++ESL++ LE++VL+ E + +L+K E +AE E+ N+ +E A L D ++ ++N L ++ +I Q E E+ L +++A E ++E+ +E+E +L + GL + + E+ ++ +++L ++ E+G QL AN +Q L +L ++RR+ + +A+Q++ + E L + +L QL E E +E+ + L+ +KE L+ +LYE+Q+ +QLE + E LE + L + + E QR E + L L + K +++++L ++E+ L ++ + ++ ++RL E+E LR + K++ + ++E +DL K++L+ EI+ +Q ER++ LL+ E KQ A+ L E EK S+ EK+ L ++ ++ER R E +I+ +QD+ ++ +LK + FE H +E KNL+ K+L ++ +E EEL++ L++AE++RD+LR+D+ E +RE E+ E R+E ++ +R+ ++ +E ET+Q SN ELR +K E ++ +Q +++ Q ++S+L+E K ++E R L+D E++ ++ RR+L+ELR QVK L E + EV+ LQ R+ +E KE ++RRE+ L+Q++ ESE+ +E +++ + LE +EK +Q E + L+E+ +L+ QL+ + L E R+ LE +++ R+ AE+ + ++S LR+ IG R + R S + G S SP +GRV+ + S DR R P +L+PE V+ ALRD Q + +RERD+ I+ + + +++ ++ + +LQ+ +++E ++G + RL +A T + + ++ + +E ER++ +++ +LE L E E + Q+R+ + R E+ E E +GL + ++ +ENR T+LEL +R LEGEL+R +M ++E E Q L++R L +Q+ D E + SLQ + RL++ L+R ++ E ++K L +L E ++Q+ + +LQ L ++E DRRVLQERL+SV+ LS++K N L + + Q E M R+ + + + + + I Q++E EQ + +E + E+L L A +E ++++I+ + EK N+L+ TLDK+++E+ R E + +++ + L + RQ Q LQ Q+ E E+ H QR+ME++ R + E+ SE +R S E TL+ RERSHRQ+V+ LEEQIN L++QL QE+++R+
Sbjct: 73 LQEENRSLQDELLRMEDLLSLTRSEREDLSIRNQALNEKLEQ-YQSHRSGE----------------TEAVLDLRQRFHEEEMAYKRKLSAYQEGQQRQAQLVQRLQDKVLQYKRRCRELEQQLLEKTSE--SEQQRLA---------LQARLDSAETKLNRMDQNHSLELNNALTRLDEEQQRSSSLAQVNNTLREQMEQLKTTNEKLTEEIKRLTSDLHKSHEDLDQREAEWRKERQNYTFYLSNEHSGILTLWRKAAALRSQFLDMRGITERGLAEIKTDISRSSRRMHTACLNLDSNL--RLSQSAAGASL---HTARLEQQLRDKVRQMMQLQSQWDAEKVELNSRVSELSLQTEKLVRENSKKEK----------------EKQILENSGCDTLQELEGVREECDSLQQVLSSITQMCQTDV-----SP---DPTCVES--TG----VSATNEM--RQSVSPLFV-----FSSSPIRRRSPTRMRSPQR-SELALKAVQNVLQRHQDREKELHSELAAARDSLEQTKKQ---QEKNQHVSEAHTEELKKENKEINTILESVKQELQRCQNSIELLTREKEDMEESLQTIKQKAEGSLLETERLKAVNAELLRQREALEEQKEELNRERDRSQKELERGQRIQEQLEEKVSILKKDLVTVRESLSQTALERDVLQGEKEAVASALSKAESSRAELELALNQMHSERATLTDSLAKMGALNEGLAQDKVALNRVILQLEGERAALHEDRRAGEANCAALKEQQEALEHEVSQLQADRVGLERRCREAEEKHKRQEEQLLGVHKERGKLQDQLAQANTLVQ----TLQDQLKESRREMDLQGSALQRAAQRMEELTSQNAELGVQLAALEDERQEHEEEFAQLRAQKESLESTLYETQRRAAQLEDRREQLEGEIHTLTLVKQSLQVETQRQALEAEEALAGLRQQKVTVELQLAQTEQAAQLSLSNQSQQHQDTVDRLKREKESLRLTMIADKQDSVQRLEKEKEDLLFDRENVKQKLSAEILRLQEEREESLLKVESEKQKALLLKETEKNSLSEKLMNTQRELSDTKMEMERCRREAQIKQEQDKTSLDNVLSELKALQSDFEDAVSAHSKENKNLRDRMKQLSQERESLNKEVEELRTQLRLAEDSRDSLRRDIIEVQRLLREKEEICESQRKETLELRRDVGDLTRERETLQKSNTELRACIKKIESERSSLQVAMEEKQQRISVLQEGKSCAEREAAHLRATLRDVERSHIEARRQLQELRRQVKTLGGESSQKEQEVAELQARIQQEEQKEQQSRRESLELRQRITESESEREAARREILTLQQHLSALESSSRQREKELEQRLSESRAGEQRLQEACKSLQEQLQRCTSESGDSRLQLGAFEARVRALEAELSKSQASRREAESHVNGLYSALRRTIGVRGRSPSPRRALSSTKGLDSSHGSPMEGRVTPSSR---GVSPDRSRS--------------PYPELEPELVKQALRDFMQELRDTQRERDEAGIQVLSLRRQLEDSINSCERLQSQQQKLQRQLADLQEGQRGTEERLGTAHTEMRLLQDNLRHSEAERQASGERIMELEHSLRICEDENRDFQDRLSRARNAENRQELECKGLREVLEASENRGTELELRKRSLEGELERTRMSLAEREAEVQTLQERAHHLQEQLKDSEDREASLQTEVQRLNLALSRAQDGERQLQEKSQGLTQALGEATAGRGNLQEDVSRLQGALTAAEQDRRVLQERLDSVRQALSDSKRHNLRLSQTIQEQQQQLEEMHLNCRELQAQLQDLQQTLIKQQQREEEQ------GAALLE---VQEKLKMLQGDKAQVELDKQEIQHSAVLLEKGNNTLRATLDKVKREQLRIEGEAQRLSVEKEQLSHSVISLRKDLAEAQRQNQYLQEQMTEMERSHTQRLMEVSLRHRQELDSESNRAHSIQQQVESTLESRERSHRQRVRGLEEQINSLQEQLEQEVRRRQ 1967
BLAST of Rootletin-2 vs. Ensembl Xenopus
Match: pgm2 (phosphoglucomutase 2 [Source:Xenbase;Acc:XB-GENE-1006723]) HSP 1 Score: 527.324 bits (1357), Expect = 1.826e-153 Identity = 588/2071 (28.39%), Postives = 1080/2071 (52.15%), Query Frame = 1
Query: 307 PQKMPEVVK---DIILRDFGDTDEDE-------DSIKDLRMPKPN------SQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLII----DTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKG----QLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRM--KATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRE 6441
P K+ V++ D++L + G + ED + +D P P +QN + S + + L+ L+ EN +L+D L +E+ L ++ER++L+I+ A+NEKL + + + + G+ + LR++ ++ YKRKL+A + Q +QA+L++RLQ KL+ R+D AE L + + +++L + + L EEQ +S SL Q+ LR+Q+++ N+ LTE+++RL+ + +L+Q++ +W+ + ++ +L E + I +LW + QF D++ ER L +++ +I +S++ + AC NLD+N RLSQ + ++LE L + + ++Q+ + LN + ++ E L +E + KEK + I N T Q + + D++ Q L I Q+ DV SP D ES TG + N + +SVSP F+S + R R +SP ++ AV++ L + + ++L S++ +A+++ KKQ E + E EL+ E + L+ +++E +R +++I +L +K +++S ++ + + E+LK +N EL R +E L + ++L+R +R KE+ER + E E K S LK+++ +++ESL++ LE++VL+ E + +L+K E +AE E+ N+ +E A L D ++ ++N L ++ +I Q E E+ L +++A E ++E+ +E+E +L + GL + + E+ ++ +++L ++ E+G QL AN +Q L +L ++RR+ + +A+Q++ + E L + +L QL E E +E+ + L+ +KE L+ +LYE+Q+ +QLE + E LE + L + + E QR E + L L + K +++++L ++E+ L ++ + ++ ++RL E+E LR + K++ + ++E +DL K++L+ EI+ +Q ER++ LL+ E KQ A+ L E EK S+ EK+ L ++ ++ER R E +I+ +QD+ ++ +LK + FE H +E KNL+ K+L ++ +E EEL++ L++AE++RD+LR+D+ E +RE E+ E R+E ++ +R+ ++ +E ET+Q SN ELR +K E ++ +Q +++ Q ++S+L+E K ++E R L+D E++ ++ RR+L+ELR QVK L E + EV+ LQ R+ +E KE ++RRE+ L+Q++ ESE+ +E +++ + LE +EK +Q E + L+E+ +L+ QL+ + L E R+ LE +++ R+ AE+ + ++S LR+ IG R + R S + G S SP +GRV+ + S DR R P +L+PE V+ ALRD Q + +RERD+ I+ + + +++ ++ + +LQ+ +++E ++G + RL +A T + + ++ + +E ER++ +++ +LE L E E + Q+R+ + R E+ E E +GL + ++ +ENR T+LEL +R LEGEL+R +M ++E E Q L++R L +Q+ D E + SLQ + RL++ L+R ++ E ++K L +L E ++Q+ + +LQ L ++E DRRVLQERL+SV+ LS++K N L + + Q E M R+ + + + + + I Q++E EQ + +E + E+L L A +E ++++I+ + EK N+L+ TLDK+++E+ R E + +++ + L + RQ Q LQ Q+ E E+ H QR+ME++ R + E+ SE +R S E TL+ RERSHRQ+V+ LEEQIN L++QL QE+++R+
Sbjct: 8 PMKLETVIQHLEDVVL-NPGSSVEDRALSVRSGEGERDALTPVPARIREIVTQNLREDSAYMSPESHLN--LSLQEENRSLQDELLRMEDLLSLTRSEREDLSIRNQALNEKLEQ-YQSHRSGE----------------TEAVLDLRQRFHEEEMAYKRKLSAYQEGQQRQAQLVQRLQDKLQA--------------------------------------RLDSAETKLNRMDQNHSLELNNALTRLDEEQQRSSSLAQVNNTLREQMEQLKTTNEKLTEEIKRLTSDLHKSHEDLDQREAEWRKERQNYTFYLSNEHSGILTLWRKAAALRSQFLDMRGITERGLAEIKTDISRSSRRMHTACLNLDSNL--RLSQSAAGASL---HTARLEQQLRDKVRQMMQLQSQWDAEKVELNSRVSELSLQTEKLVRENSKKEK----------------EKQILENSGCDTLQELEGVREECDSLQQVLSSITQMCQTDV-----SP---DPTCVES--TG----VSATNEM--RQSVSPLFV-----FSSSPIRRRSPTRMRSP-QRSELALKAVQNVLQRHQDREKELHSELAAARDSLEQTKKQ---QEKNQHVSEAHTEELKKENKEINTILESVKQELQRCQNSIELLTREKEDMEESLQTIKQKAEGSLLETERLKAVNAELLRQREALEEQKEELNRERDRSQKELERGQRIQEQLEEKVSILKKDLVTVRESLSQTALERDVLQGEKEAVASALSKAESSRAELELALNQMHSERATLTDSLAKMGALNEGLAQDKVALNRVILQLEGERAALHEDRRAGEANCAALKEQQEALEHEVSQLQADRVGLERRCREAEEKHKRQEEQLLGVHKERGKLQDQLAQANTLVQ----TLQDQLKESRREMDLQGSALQRAAQRMEELTSQNAELGVQLAALEDERQEHEEEFAQLRAQKESLESTLYETQRRAAQLEDRREQLEGEIHTLTLVKQSLQVETQRQALEAEEALAGLRQQKVTVELQLAQTEQAAQLSLSNQSQQHQDTVDRLKREKESLRLTMIADKQDSVQRLEKEKEDLLFDRENVKQKLSAEILRLQEEREESLLKVESEKQKALLLKETEKNSLSEKLMNTQRELSDTKMEMERCRREAQIKQEQDKTSLDNVLSELKALQSDFEDAVSAHSKENKNLRDRMKQLSQERESLNKEVEELRTQLRLAEDSRDSLRRDIIEVQRLLREKEEICESQRKETLELRRDVGDLTRERETLQKSNTELRACIKKIESERSSLQVAMEEKQQRISVLQEGKSCAEREAAHLRATLRDVERSHIEARRQLQELRRQVKTLGGESSQKEQEVAELQARIQQEEQKEQQSRRESLELRQRITESESEREAARREILTLQQHLSALESSSRQREKELEQRLSESRAGEQRLQEACKSLQEQLQRCTSESGDSRLQLGAFEARVRALEAELSKSQASRREAESHVNGLYSALRRTIGVRGRSPSPRRALSSTKGLDSSHGSPMEGRVTPSSR---GVSPDRSRS--------------PYPELEPELVKQALRDFMQELRDTQRERDEAGIQVLSLRRQLEDSINSCERLQSQQQKLQRQLADLQEGQRGTEERLGTAHTEMRLLQDNLRHSEAERQASGERIMELEHSLRICEDENRDFQDRLSRARNAENRQELECKGLREVLEASENRGTELELRKRSLEGELERTRMSLAEREAEVQTLQERAHHLQEQLKDSEDREASLQTEVQRLNLALSRAQDGERQLQEKSQGLTQALGEATAGRGNLQEDVSRLQGALTAAEQDRRVLQERLDSVRQALSDSKRHNLRLSQTIQEQQQQLEEMHLNCRELQAQLQDLQQTLIKQQQREEEQ------GAALLE---VQEKLKMLQGDKAQVELDKQEIQHSAVLLEKGNNTLRATLDKVKREQLRIEGEAQRLSVEKEQLSHSVISLRKDLAEAQRQNQYLQEQMTEMERSHTQRLMEVSLRHRQELDSESNRAHSIQQQVESTLESRERSHRQRVRGLEEQINSLQEQLEQEVRRRQ 1944
BLAST of Rootletin-2 vs. Ensembl Xenopus
Match: CROCC (ciliary rootlet coiled-coil, rootletin [Source:NCBI gene;Acc:100486658]) HSP 1 Score: 417.542 bits (1072), Expect = 1.116e-119 Identity = 317/878 (36.10%), Postives = 504/878 (57.40%), Query Frame = 1
Query: 3487 HRLNRDKEELA-----------QEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKE-LENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPG--------SDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNS 6060
HRL +++EEL +EI +Q+ERD+ LL+AE KQ A+++ E EK S+ EK+S L +LER + + +IR +QD+ TI N +LK R Q E+ + HDRE+K L +E L E EELK+ L + E+ RD +R++L E+ ++RE ++ E ++E M+ +R + KE E +Q SN+ELR ++ +E ++I ++R ++ + +LS+LEE + +KEV D R +L+D E++R++ RREL++LR Q+K LD E K +++ +Q R++T E +E E+RR+NF LKQK++E+EA +E K+L RK E+E +E+ + DE + K L ++ NLE +L+ +L LS E R+ LE +++ L+ ++ E +L ++HS LR+ +G GR S + GR G + P +D+DPE VR ALRD Q + ERERD++ + S E + D A+ R+ QLQK E EE K+ +D +L QT L++QEET+ R ERERK +K LER L E E++ Q++++K++ E+ +E ERR L + +D +E+R T+LEL RRGLEGELQR K+ D+E E Q ++ R++AL +Q+SD E + +LQL ++RL+ LA+ +E E + K+KV L +LS+ S DKL QLQ L SEH+RR+LQERLE+ + ++E K QN L+++ + + E E E ++ E+EG+++++ +IL QRQE E + + E+ +L ERL L ++ LESE+R++E+ ++ EK+KN+
Sbjct: 470 HRLTQEREELVARHEMEREEMSEEIAALQQERDESLLQAEFEKQQALSVKESEKASLSEKLSHAQHGLSGLSLELERHKRDSQIRQEQDRGTILALNSELKGLRGQLEEALVLHDRELKGLNDKSREPLGLDLIGCCLEVEELKTQLCVVEDARDAVRRELIEAHRRVREGQELLEGHKKENMELRRALGDEAKEKEAVQKSNEELRGAVRRAESERISLKRSNEEKEQRLSVLEEARGASEKEVNDLRSSLRDVERSRLEARRELQDLRRQLKLLDDESIKRSRDMAEVQARLSTYEQREEESRRDNFTLKQKLMETEAGREAARKELSALQRKVAEVEGEFGVRERELQGSLDEARGNEKKLLDNTRNLEIKLQAAQEESGQLGLRLSASEGRVHGLEAELSRLEGLKREVEFKLGSLHSALRRTLGI--------------------------GRAGRTPSPAYR--------GRSGSPKSKTPERPPSPTRGEQLVADIDPEVVRAALRDFLQELRDTERERDELRTQLGTSNRHLAEMEAERDGAITRVQQLQKVLSECEEAKRNVDGKLGGLQTTLILQEETLRRYERERKLAQEKAASLERSLQAAEGEQRAAQDKMNKIKANEAKYENERRRLKEVLDASESRNTKLELSRRGLEGELQRHKLVLADREAEMQEMQQRMEALQRQLSDSEGRVGTLQLCVERLNSTLAKAQESETSLKEKVQSLTGALSDSNCTSASSHDKLNQLQKVLTGSEHERRILQERLEAARQAVAEGKKQNVALMEQNQVLRDEQAEGELQRAELEGQVRQMQEILRQRQESEGASLRNVQKLQEEREVLQERLCGLQRAVVQLESEKREVERSSMRLEKDKNA 1313 HSP 2 Score: 209.534 bits (532), Expect = 1.503e-53 Identity = 151/402 (37.56%), Postives = 242/402 (60.20%), Query Frame = 1
Query: 2014 LTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQL--ETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQL 3213
L ++++ + S++KQL D+ENERR LE++ +L+ E D +D +R+ R+R+ I L +K L+KS N EE +Q+ EKL+ N +LQR ++ L + +D+ R+ ER + V+R K+ E E K S L++E+ +KESL++ LE+EV E E ++ +L+K E AE E+ N+ +TEEA LRD ++ ++N L ++ +E II Q E E+ L G+K +EQEK IR+EL+R+E EK EL+ + GL S+Q +E++ E L E+ L E+GQL + V+L ++ +L+Q+RRD E S + ++ ++KE L K+K L+ QLT E E R A+ I VL+ EKE L+ +L+E+QQ + + ++ E LE Q L
Sbjct: 23 LRGRLDAGQETVGSLRKQLSDNENERRALEQKIQQLQQERDVMGGAKEDAERDVTRLRNHIEQLNGEKGALEKSLQNLQEELNGQRQENEKLQLANSDLQRQRDLLQEEKEDVCRDRERALQNVDRGHKAQEQLEVKLSALRKELVVVKESLHKCSLEREVSEAERVDVSQALSKAETRLAELELTLNRQRTEEASLRDALSKMSALNESLAQDKTELSRIIAQLEEERAHLQGQKHEVEQEKASIRDELVRLEQEKLELDTERFGLDNSLQAMEQNREKLLQEVQALRKERGQLQEQLGQVSLL----SIRDDLVQSRRDVELQSECLLRASREKEELMKDKGSLVVQLTASERESRALAEEIAVLRTEKEALETALFEAQQQLIHVTSRKEQLEVESQNL 420
BLAST of Rootletin-2 vs. Ensembl Xenopus
Match: ENSXETT00000012599.1 (centrosomal protein 250 [Source:NCBI gene;Acc:100498015]) HSP 1 Score: 82.4185 bits (202), Expect = 1.139e-14 Identity = 43/140 (30.71%), Postives = 80/140 (57.14%), Query Frame = 1
Query: 982 DLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQL 1401
+LE + +L+EEQ + +L + ALLR+ L AN+ L D+ +L+ + + EL+ K+ DW+ + ++ + GE +R+ +W VV F+R F ++KS+ ERDL +R + + ++ CS+L + ++ L L
Sbjct: 63 ELERALQKLEEEQQRCENLAAVNALLREDLGHTQEANKVLCNDMHKLTADWTSALQELKHKENDWEQEREHYNSLMKGEHSRLLRIWTEVVTFRRHFRELKSATERDLSSVRADWSRCLCLIQSCCSSLKSYKIHGLPVL 202
BLAST of Rootletin-2 vs. Ensembl Mouse
Match: Crocc (ciliary rootlet coiled-coil, rootletin [Source:MGI Symbol;Acc:MGI:3529431]) HSP 1 Score: 776.163 bits (2003), Expect = 0.000e+0 Identity = 674/2028 (33.23%), Postives = 1114/2028 (54.93%), Query Frame = 1
Query: 460 LDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSL-SKMKEEFRKTETQYQKQIES--LNEQFVHVNRSNESLTKELADKEKV-------LTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVD---QVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNK-SPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQ------EKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGD---------VNQYSESVIPG-------SDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKK 6435
+ S+ L+ EN L+ L VE+ L + + ERD LAIK+NA+NE+L + R+ E L Q+++LR+QL ++ Y+RKL A + Q +QA+L++RLQ K+ Q +Q S+L ++ ++R ++ + L+ +T+ + DL+S + L+EEQ +S SL Q+ A+LR+QLD+A ANQ L+ED+++++ + + ELEQ++ W+ +E +F+ + E +R+ LW V+ +RQ +++K ERDL QL + +++++++ L + S+ + L+ +K +QLE L +K+ E + Q Q ++ L+ + + S E L + ++K++V L L LR LD D + + Q LRD+AQ ++D + Q+ S D + G S+ R+ +P R S R R R SP ST + SALHKR LQVQD+ + +++ SV+KQL DSE ERR LE+Q LR + ++ + +D QRE +R+R +L +K L S + ++ K +Q++EKL+ EL+R L D +D + R +E+ER + +E E K S L +E+ ++E+L+ A+L+++VL+ E + + ++L K E +A+ E+ K + EEA LRD ++ ++N L ++ E +I Q E EK L G ++ E EK + E+L R+E E E + GL S+ E++ E L+ ++ L E+ L+ L R+ + EL QA R+++R A++++ ++KE +AKE+ L +L E E R ++ L+ EKE L+ SL++ Q+ ++QLEA+ E LE++ Q L + + E L+ + +K + KE + KL ++E+E LR ++ A EED++RL E+E E + +++ Q Q+E ++L R+ +KEEL++EI +Q+ERD+ LL AE KQ A++L E EK ++ EK+ L ++ER + + + R +QD+NT+ +L+ R Q E+ H + +K L+ L Q+ MRE EEL++ L++ E+TRD LR++L E+ K R+++D E R+E + +R+ E KE E ++ SN+ELR +K +E ++I ++ +D + KL++LEE + + KE + R +LQ+ E++R++ RREL+ELR Q+K LD++ G+L E++ LQ R+A E E E+RRE GL+Q++++ E++ E L ++L S RK +E E ++E+ +E K L +S +LE +LE EL LS E R LE ++ ++ +R+ AE +L + S LR+ +G GRVSS + E G GD + S+ PG DLDPEAVR ALRD Q + S +RERD+++++ + + E + D A R QLQK E EE + D RLS AQ L +QEE++ R++RE ++ +D++ LER L E+E + QE+V KM+ E+ E ++R L + +D +E+R +LEL RR LEGELQR ++G D+E Q L+DRVD+L +Q++D E KA +LQLT++RLS LA+ EE E + KV L +L++ +L S QDK + LQ L++ EHDR+VLQERL++ + LSEA+ Q+ +L ++++ + EL E ++ + EG++++L Q L QRQE E + + E+ LL ERL SL +LA LE+E+RD+E+ ++ +K++ +L+KTLDK+E+EK RS E + +R D E + +Q+Q L+ Q+ A + + + + E+ E++RL+SA TE+TL+ RER+HRQ+V LEEQ++ LK QL QEL++
Sbjct: 75 MASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVNERLEQAV--------RLETGELEAQEPRGLVRQSVELRRQLQEEQSSYRRKLQAYQEGQQRQAQLVQRLQAKILQY----------KKQCSELEKQL-------------MDRSTELEQQRLR--DTEHSQDLDSALLRLEEEQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFSSEHSRLLRLWRQVMGLRRQASEVKMGTERDLLQLGGELVRTSRAVQELGLGLSASLHRAESKAEAALEKQKLLQAQLEEQLQAKLLREKDLAQLQVQSDLDKADLSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRLQEQTTLDTE--------------DGEGLQQTLRDLAQAALSDTESGVQLSSSERTADT------SDG------SLRGFSGQRTPTPPRHSP---------GRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQL-RLEQEVE-----RQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGL--------------------------GRVSSSPAREAP-------AGGSGDGLSSPSPLEYSPRSQPPSPGLIASPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEEQVSTLKAQLHQELRR 1995
BLAST of Rootletin-2 vs. Ensembl Mouse
Match: Crocc (ciliary rootlet coiled-coil, rootletin [Source:MGI Symbol;Acc:MGI:3529431]) HSP 1 Score: 732.635 bits (1890), Expect = 0.000e+0 Identity = 634/1900 (33.37%), Postives = 1052/1900 (55.37%), Query Frame = 1
Query: 844 LNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSL-SKMKEEFRKTETQYQKQIES--LNEQFVHVNRSNESLTKELADKEKV-------LTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVD---QVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNK-SPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQ------EKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGD---------VNQYSESVIPG-------SDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKK 6435
L ++N L+ E+SR+++ + ++ + + I N + +T+ + DL+S + L+EEQ +S SL Q+ A+LR+QLD+A ANQ L+ED+++++ + + ELEQ++ W+ +E +F+ + E +R+ LW V+ +RQ +++K ERDL QL + +++++++ L + S+ + L+ +K +QLE L +K+ E + Q Q ++ L+ + + S E L + ++K++V L L LR LD D + + Q LRD+AQ ++D + Q+ S D + G S+ R+ +P R S R R R SP ST + SALHKR LQVQD+ + +++ SV+KQL DSE ERR LE+Q LR + ++ + +D QRE +R+R +L +K L S + ++ K +Q++EKL+ EL+R L D +D + R +E+ER + +E E K S L +E+ ++E+L+ A+L+++VL+ E + + ++L K E +A+ E+ K + EEA LRD ++ ++N L ++ E +I Q E EK L G ++ E EK + E+L R+E E E + GL S+ E++ E L+ ++ L E+ L+ L R+ + EL QA R+++R A++++ ++KE +AKE+ L +L E E R ++ L+ EKE L+ SL++ Q+ ++QLEA+ E LE++ Q L + + E L+ + +K + KE + KL ++E+E LR ++ A EED++RL E+E E + +++ Q Q+E ++L R+ +KEEL++EI +Q+ERD+ LL AE KQ A++L E EK ++ EK+ L ++ER + + + R +QD+NT+ +L+ R Q E+ H + +K L+ L Q+ MRE EEL++ L++ E+TRD LR++L E+ K R+++D E R+E + +R+ E KE E ++ SN+ELR +K +E ++I ++ +D + KL++LEE + + KE + R +LQ+ E++R++ RREL+ELR Q+K LD++ G+L E++ LQ R+A E E E+RRE GL+Q++++ E++ E L ++L S RK +E E ++E+ +E K L +S +LE +LE EL LS E R LE ++ ++ +R+ AE +L + S LR+ +G GRVSS + E G GD + S+ PG DLDPEAVR ALRD Q + S +RERD+++++ + + E + D A R QLQK E EE + D RLS AQ L +QEE++ R++RE ++ +D++ LER L E+E + QE+V KM+ E+ E ++R L + +D +E+R +LEL RR LEGELQR ++G D+E Q L+DRVD+L +Q++D E KA +LQLT++RLS LA+ EE E + KV L +L++ +L S QDK + LQ L++ EHDR+VLQERL++ + LSEA+ Q+ +L ++++ + EL E ++ + EG++++L Q L QRQE E + + E+ LL ERL SL +LA LE+E+RD+E+ ++ +K++ +L+KTLDK+E+EK RS E + +R D E + +Q+Q L+ Q+ A + + + + E+ E++RL+SA TE+TL+ RER+HRQ+V LEEQ++ LK QL QEL++
Sbjct: 7 LQEENQLLQQELSRVEDLLAQSRAERDE-LAIKYNAVNERDTEHSQDLDSALLRLEEEQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFSSEHSRLLRLWRQVMGLRRQASEVKMGTERDLLQLGGELVRTSRAVQELGLGLSASLHRAESKAEAALEKQKLLQAQLEEQLQAKLLREKDLAQLQVQSDLDKADLSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRLQEQTTLDTE--------------DGEGLQQTLRDLAQAALSDTESGVQLSSSERTADT------SDG------SLRGFSGQRTPTPPRHSP---------GRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQL-RLEQEVE-----RQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGL--------------------------GRVSSSPAREAP-------AGGSGDGLSSPSPLEYSPRSQPPSPGLIASPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEEQVSTLKAQLHQELRR 1831
BLAST of Rootletin-2 vs. Ensembl Mouse
Match: Crocc (ciliary rootlet coiled-coil, rootletin [Source:MGI Symbol;Acc:MGI:3529431]) HSP 1 Score: 732.635 bits (1890), Expect = 0.000e+0 Identity = 634/1900 (33.37%), Postives = 1052/1900 (55.37%), Query Frame = 1
Query: 844 LNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSL-SKMKEEFRKTETQYQKQIES--LNEQFVHVNRSNESLTKELADKEKV-------LTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVD---QVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNK-SPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQ------EKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGD---------VNQYSESVIPG-------SDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKK 6435
L ++N L+ E+SR+++ + ++ + + I N + +T+ + DL+S + L+EEQ +S SL Q+ A+LR+QLD+A ANQ L+ED+++++ + + ELEQ++ W+ +E +F+ + E +R+ LW V+ +RQ +++K ERDL QL + +++++++ L + S+ + L+ +K +QLE L +K+ E + Q Q ++ L+ + + S E L + ++K++V L L LR LD D + + Q LRD+AQ ++D + Q+ S D + G S+ R+ +P R S R R R SP ST + SALHKR LQVQD+ + +++ SV+KQL DSE ERR LE+Q LR + ++ + +D QRE +R+R +L +K L S + ++ K +Q++EKL+ EL+R L D +D + R +E+ER + +E E K S L +E+ ++E+L+ A+L+++VL+ E + + ++L K E +A+ E+ K + EEA LRD ++ ++N L ++ E +I Q E EK L G ++ E EK + E+L R+E E E + GL S+ E++ E L+ ++ L E+ L+ L R+ + EL QA R+++R A++++ ++KE +AKE+ L +L E E R ++ L+ EKE L+ SL++ Q+ ++QLEA+ E LE++ Q L + + E L+ + +K + KE + KL ++E+E LR ++ A EED++RL E+E E + +++ Q Q+E ++L R+ +KEEL++EI +Q+ERD+ LL AE KQ A++L E EK ++ EK+ L ++ER + + + R +QD+NT+ +L+ R Q E+ H + +K L+ L Q+ MRE EEL++ L++ E+TRD LR++L E+ K R+++D E R+E + +R+ E KE E ++ SN+ELR +K +E ++I ++ +D + KL++LEE + + KE + R +LQ+ E++R++ RREL+ELR Q+K LD++ G+L E++ LQ R+A E E E+RRE GL+Q++++ E++ E L ++L S RK +E E ++E+ +E K L +S +LE +LE EL LS E R LE ++ ++ +R+ AE +L + S LR+ +G GRVSS + E G GD + S+ PG DLDPEAVR ALRD Q + S +RERD+++++ + + E + D A R QLQK E EE + D RLS AQ L +QEE++ R++RE ++ +D++ LER L E+E + QE+V KM+ E+ E ++R L + +D +E+R +LEL RR LEGELQR ++G D+E Q L+DRVD+L +Q++D E KA +LQLT++RLS LA+ EE E + KV L +L++ +L S QDK + LQ L++ EHDR+VLQERL++ + LSEA+ Q+ +L ++++ + EL E ++ + EG++++L Q L QRQE E + + E+ LL ERL SL +LA LE+E+RD+E+ ++ +K++ +L+KTLDK+E+EK RS E + +R D E + +Q+Q L+ Q+ A + + + + E+ E++RL+SA TE+TL+ RER+HRQ+V LEEQ++ LK QL QEL++
Sbjct: 7 LQEENQLLQQELSRVEDLLAQSRAERDE-LAIKYNAVNERDTEHSQDLDSALLRLEEEQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFSSEHSRLLRLWRQVMGLRRQASEVKMGTERDLLQLGGELVRTSRAVQELGLGLSASLHRAESKAEAALEKQKLLQAQLEEQLQAKLLREKDLAQLQVQSDLDKADLSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRLQEQTTLDTE--------------DGEGLQQTLRDLAQAALSDTESGVQLSSSERTADT------SDG------SLRGFSGQRTPTPPRHSP---------GRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQL-RLEQEVE-----RQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGL--------------------------GRVSSSPAREAP-------AGGSGDGLSSPSPLEYSPRSQPPSPGLIASPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEEQVSTLKAQLHQELRR 1831
BLAST of Rootletin-2 vs. Ensembl Mouse
Match: Crocc (ciliary rootlet coiled-coil, rootletin [Source:MGI Symbol;Acc:MGI:3529431]) HSP 1 Score: 732.635 bits (1890), Expect = 0.000e+0 Identity = 634/1900 (33.37%), Postives = 1052/1900 (55.37%), Query Frame = 1
Query: 844 LNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSL-SKMKEEFRKTETQYQKQIES--LNEQFVHVNRSNESLTKELADKEKV-------LTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVD---QVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNK-SPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQ------EKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGD---------VNQYSESVIPG-------SDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKK 6435
L ++N L+ E+SR+++ + ++ + + I N + +T+ + DL+S + L+EEQ +S SL Q+ A+LR+QLD+A ANQ L+ED+++++ + + ELEQ++ W+ +E +F+ + E +R+ LW V+ +RQ +++K ERDL QL + +++++++ L + S+ + L+ +K +QLE L +K+ E + Q Q ++ L+ + + S E L + ++K++V L L LR LD D + + Q LRD+AQ ++D + Q+ S D + G S+ R+ +P R S R R R SP ST + SALHKR LQVQD+ + +++ SV+KQL DSE ERR LE+Q LR + ++ + +D QRE +R+R +L +K L S + ++ K +Q++EKL+ EL+R L D +D + R +E+ER + +E E K S L +E+ ++E+L+ A+L+++VL+ E + + ++L K E +A+ E+ K + EEA LRD ++ ++N L ++ E +I Q E EK L G ++ E EK + E+L R+E E E + GL S+ E++ E L+ ++ L E+ L+ L R+ + EL QA R+++R A++++ ++KE +AKE+ L +L E E R ++ L+ EKE L+ SL++ Q+ ++QLEA+ E LE++ Q L + + E L+ + +K + KE + KL ++E+E LR ++ A EED++RL E+E E + +++ Q Q+E ++L R+ +KEEL++EI +Q+ERD+ LL AE KQ A++L E EK ++ EK+ L ++ER + + + R +QD+NT+ +L+ R Q E+ H + +K L+ L Q+ MRE EEL++ L++ E+TRD LR++L E+ K R+++D E R+E + +R+ E KE E ++ SN+ELR +K +E ++I ++ +D + KL++LEE + + KE + R +LQ+ E++R++ RREL+ELR Q+K LD++ G+L E++ LQ R+A E E E+RRE GL+Q++++ E++ E L ++L S RK +E E ++E+ +E K L +S +LE +LE EL LS E R LE ++ ++ +R+ AE +L + S LR+ +G GRVSS + E G GD + S+ PG DLDPEAVR ALRD Q + S +RERD+++++ + + E + D A R QLQK E EE + D RLS AQ L +QEE++ R++RE ++ +D++ LER L E+E + QE+V KM+ E+ E ++R L + +D +E+R +LEL RR LEGELQR ++G D+E Q L+DRVD+L +Q++D E KA +LQLT++RLS LA+ EE E + KV L +L++ +L S QDK + LQ L++ EHDR+VLQERL++ + LSEA+ Q+ +L ++++ + EL E ++ + EG++++L Q L QRQE E + + E+ LL ERL SL +LA LE+E+RD+E+ ++ +K++ +L+KTLDK+E+EK RS E + +R D E + +Q+Q L+ Q+ A + + + + E+ E++RL+SA TE+TL+ RER+HRQ+V LEEQ++ LK QL QEL++
Sbjct: 7 LQEENQLLQQELSRVEDLLAQSRAERDE-LAIKYNAVNERDTEHSQDLDSALLRLEEEQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFSSEHSRLLRLWRQVMGLRRQASEVKMGTERDLLQLGGELVRTSRAVQELGLGLSASLHRAESKAEAALEKQKLLQAQLEEQLQAKLLREKDLAQLQVQSDLDKADLSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRLQEQTTLDTE--------------DGEGLQQTLRDLAQAALSDTESGVQLSSSERTADT------SDG------SLRGFSGQRTPTPPRHSP---------GRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQL-RLEQEVE-----RQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGL--------------------------GRVSSSPAREAP-------AGGSGDGLSSPSPLEYSPRSQPPSPGLIASPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEEQVSTLKAQLHQELRR 1831
BLAST of Rootletin-2 vs. Ensembl Mouse
Match: Crocc2 (ciliary rootlet coiled-coil, rootletin family member 2 [Source:MGI Symbol;Acc:MGI:3045962]) HSP 1 Score: 156.762 bits (395), Expect = 1.693e-37 Identity = 173/640 (27.03%), Postives = 310/640 (48.44%), Query Frame = 1
Query: 3445 EIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGR---FGDVNQYSESVIPGS-DLDPEA-------VRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQA------LQ-RINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMR 5310
E ++ E+ +L R D+E L EI +++ERD+ LL+ E Q A++L + EK + +++S + +LER R E + + Q + T+ T +L+ ++QFE+ H RE L+ +E+ ++ RE EEL++ L +A E LRQ+L S E+ RE L+RE + +R + +E + +Q SN ELR + +E +K ++R ++ + KL +L+E + QKE + R LQ+ E+A+ D RR+L+E QV+ L+ E + EVS LQ +V+ D + +E+ L+++V E++A + + K++ +K E+E ++ K + + E + ++L+ + +L+ ++ + L +L +R+ +LE ++ + R AE +L + S L +G + + S + + R GR YS + P +DP++ VR ALRD+ Q ++ ++ERD+ I+ N S QL +A LQ R+ QLQ++ + EE ++ +S L SAQ A +Q+E + R E E + G+ E++ LQE+VD +R
Sbjct: 919 EAAARWMEQQKELLTRSAADREALQGEIQNLKQERDESLLQLEHEMQQALSLKDAEKSLLSKELS-------GAHRELERARQEAQNQQVQAEATVTTMTKELRTLQVQFEEAISTHQREADTLREKLREIAAERSSVRREAEELQAQLNVAHERLAELRQELQAS-------EESREGLQREALGARRALEDEVQEKDVLQHSNTELRASIHRAEQEKASLKRSKEEQEQKLLLLQEAQVAAQKEAYELRTRLQELERAQRDTRRKLQERHRQVRTLEAENQRKRQEVSDLQAQVSRDAQHRQKNLQESLELQRQVAEAQAAHDGVQKEVLGLRQKLAEVEASGETRAKQLEGHLCESQRAEQTLQAELCRITRKLQEASNQADSLQRSLDNACSRVHVLEQELAKAEGARCNAEAQLGRLWSTLCSGLGQSRNLL-----------------------ASPKRPHSPTTGSSQTRPGRQRTSPPTRSYSPARWPSPVPVDPKSEVIDVAFVRDALRDLVQGLLEAQQERDNSGIQVAN-------LSSQLSEAERERLRLQSRVEQLQRDLADAEEGQRRAESALQSAQAARALQKEALQRLETEHLASARAAGQ----------ERRRLQEQVDTLR 1504 HSP 2 Score: 135.576 bits (340), Expect = 4.669e-31 Identity = 175/769 (22.76%), Postives = 353/769 (45.90%), Query Frame = 1
Query: 886 LKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTL----HKLRNGMNGDLDNSIYNNDDSATRQLIID-----TDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEH--EL--RENADAIYVLQEEKEQLDGSLYESQ 3153
L + + L R+D E L+ +E + +MDLE ++ L+ Q +SM L Q+ LLR QL+ AN L ++ R + L+ +LE ++ R + + I LW + ++++S ER L ++ ++ ++ Q L +AC NLD+ H+ RL T + S LE L + E + + Q+ + +L + E L+ + E+ + TL +L++ +G QL +D +++H L I ++ +D + W + E++ + P RSVSP + R R SP S+ AV++A+ +R + Q+L ++ S++ +++QL E R ++ + E++ +L+ ++E + + ++ +LE +K L+ + + + + +KL+ N EL+R + +L + ER +E+E +E E K S L++E+++ +E+L+ L++++LE E L +L + E A+ E+ + K E +D ++ ++ L ++ + Q E E+ +L ++K L+QE+ G+RE+L + + + + L ++ ++E+ ++L+ ++ L E QL + ++ AL +L Q+ +D E +Q+++ +K L++E+ L+++ E EL +E AD L+ E+ L+ SL+E+Q
Sbjct: 116 LASRCHMVSQRLQARLDTTEARLRKSELEHSMDLEEALSRLEASQQRSMGLSQVNTLLRQQLEHMQKANDTLARELTRATHSLVHLQRKLELQE---------SQRLSLRQPRDILPLWRQAKALQTHLAELRASTERGLTDVQADMTRTAQRLHMACLNLDS-HL-RL--------TASSMTSDLEQRLREQAREMLQLQGQWAAEKVALQARLSEQTLLVEKLSVQKEQGERAILTLKSDIQRLKSRRSGG--------------QLAVDELRDEVESLHHVLASIKEVAQSDA-MCPELAWSSSIEVREAQARLRSPP----------RSVSPHQ-------------RMSPARTSSPTSL-HPALQAVQAAIERRQQREQELRLRLESSQEEAAGLREQLSGYRQELRTSQRLLQDRAQEHEDLLGQLEAQRQEAQLSQASVHLLEREKEALETTMEELRAKADIREAETQKLEVTNAELRRSLLLRAEQKAELAQQSERSLRELEASQGRVEQLEEKVSGLRKELATSREALSSMQLQRDILETEKESLHGALAQAESGNADLELLVTRLKAEGMEQQDSLAKMAALLEGLSQDKGTLNHLALQLEQERDQLREQQKMLQQEQAGMREQLTQTGQQLGLIRAERRSLKETCGHLEQKQDHLEKQVVLLGQENAQLREQVGQVTNKKQALEKQLAQSLQDQEAQMDILQEALHEKNTLSEERAQLLAKQEALERHSELVTKEAAD----LRAERNSLENSLFEAQ 822
BLAST of Rootletin-2 vs. UniProt/SwissProt
Match: sp|Q5TZA2|CROCC_HUMAN (Rootletin OS=Homo sapiens OX=9606 GN=CROCC PE=1 SV=1) HSP 1 Score: 786.563 bits (2030), Expect = 0.000e+0 Identity = 694/2093 (33.16%), Postives = 1157/2093 (55.28%), Query Frame = 1
Query: 271 GIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNC--SQLENSLSKMKEEFRKTETQYQKQIES------LNEQFVHVNRSNESLTKELADKEKV-------LTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVD---QVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSS--RNSVEFNFSEDRKRVGRFGDVNQYS--------------ESVIPGS-DLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSAL--KSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMEL-TSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKK 6435
G+G DL+ + +P ++++I+ R+ +Q S + + S+ L+ EN L+ L VE+ L + + ERD LAIK+NA++E+L + R+ E L Q+++LR+QL ++ Y+RKL A + Q +QA+L++RLQ K+ Q + R S L+ L R ++ + L+ +T+ + DLES + L+EEQ +S SL Q+ A+LR+QLD+A +ANQ L+ED+++++ + + + ELE ++ W+ +E +F+ + E +R+ LW VV F+R +++K ERDL QL + +++++++ A L T RL++ + + EK +QLE L +++ + + Q+Q++S L+ + + + + L K+ +K++V L L LR L+ D + + Q LRD+AQ V++D + Q+ S D + G S+ L R+ SP R RS G R R SP ST A + SALHKR LQVQD+ + ++++ +++KQL DSE+ERR LE+Q LR + D + +D QRE +R+R +L +K L S + ++ + +Q+ EKL+ EL+R ++ L + +D ++ R +E+ER + +E E K S L +E+ ++E+L+RA L++++L+ E + + ++L K E + E E+ K + EEA L+D +L ++N L ++ + ++ Q E EK L G ++ EQE REE R+E + E + GL S++ E++ E L+ +L L +E+ QL+ L R+ + EL QARR+A+R A++++ ++KE LAKE L QL E E R ++ L+ EKE L+GSL+E Q+ ++QLEA+ E LE+ Q L + + E L+ + +K S KE + KL ++E+E LR ++ A EED++RL E+E E + +++ Q Q E ++L RL +KEEL++EI +Q+ERD+ LL AE KQ A++L E EK ++ EK+ L T ++ER + + + R +QD++T+ +L+ R Q E+ H +E++ LQ ++L Q+ +RE EEL++ L++ E+ RD LR++L E+ K+RE+++ RE R+E + +R+ E KE E ++ SN+ELR +K +E ++I ++ +D + KL++LEE + + KE + R LQ+ E++R++ RREL+ELR Q+K LD+E +L E++ LQ R+A E E E+RRE GL+Q++++ EA+ E + ++L + RK +E E ++E+ +E K + LE +LE EL LS E R LE ++ ++ +R+ AE +L + S LR+ +G GR S V + + D G +N S + P S DLDPEAVR ALR+ Q + S +RERD E++ + SAL + E + D A R QLQK E EE ++ +D RLS Q L +QEE++ R+ERER++ +D+V LER L E+E + QE++ KM+ E+ E ++R L + +D +E+R +LEL RR LEGELQR ++G +D+E + Q L+DRVD+L +Q++D E KA +LQLT++RL+ LA+ EE E +DKV L +L++ +L S +DK + LQ L + EHDR+VLQERL++ + LSEA+ Q+ +L ++++ + E+ + E ++ E EG++++L ++L QRQE E + + + E+ LL ERL SL +LA LE+E+R++E+ ++ EK++ +L++TLDK+E+EK RS E + ++ D E E RQ+Q+L+ Q+ EQ H+ +E+ + + E+ E++RL+SA TE+TL+ RER+HRQ+V+ LEEQ++ LK QL QEL++
Sbjct: 32 GLGARDLAQDAQITSLPALIREIVTRNL----------------------SQPESPVLLPATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQAL--------RLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKR-----------------CSELEQQL------LERSGELEQQRLR--DTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGL--RLAESRAEAALEKQALLQAQLEEQL---RDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETE--------------DGEGLQQTLRDLAQAVLSDSESGVQLSGSERTAD------ASNG------SLRGLSGQRTPSPPR---RSSPGRGRSPR----RGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGL--------------------------GRAPSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRERD--ELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKGQLQQELRR 2003
BLAST of Rootletin-2 vs. UniProt/SwissProt
Match: sp|Q8CJ40|CROCC_MOUSE (Rootletin OS=Mus musculus OX=10090 GN=Crocc PE=1 SV=2) HSP 1 Score: 776.163 bits (2003), Expect = 0.000e+0 Identity = 674/2028 (33.23%), Postives = 1114/2028 (54.93%), Query Frame = 1
Query: 460 LDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSL-SKMKEEFRKTETQYQKQIES--LNEQFVHVNRSNESLTKELADKEKV-------LTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVD---QVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNK-SPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQ------EKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGD---------VNQYSESVIPG-------SDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKK 6435
+ S+ L+ EN L+ L VE+ L + + ERD LAIK+NA+NE+L + R+ E L Q+++LR+QL ++ Y+RKL A + Q +QA+L++RLQ K+ Q +Q S+L ++ ++R ++ + L+ +T+ + DL+S + L+EEQ +S SL Q+ A+LR+QLD+A ANQ L+ED+++++ + + ELEQ++ W+ +E +F+ + E +R+ LW V+ +RQ +++K ERDL QL + +++++++ L + S+ + L+ +K +QLE L +K+ E + Q Q ++ L+ + + S E L + ++K++V L L LR LD D + + Q LRD+AQ ++D + Q+ S D + G S+ R+ +P R S R R R SP ST + SALHKR LQVQD+ + +++ SV+KQL DSE ERR LE+Q LR + ++ + +D QRE +R+R +L +K L S + ++ K +Q++EKL+ EL+R L D +D + R +E+ER + +E E K S L +E+ ++E+L+ A+L+++VL+ E + + ++L K E +A+ E+ K + EEA LRD ++ ++N L ++ E +I Q E EK L G ++ E EK + E+L R+E E E + GL S+ E++ E L+ ++ L E+ L+ L R+ + EL QA R+++R A++++ ++KE +AKE+ L +L E E R ++ L+ EKE L+ SL++ Q+ ++QLEA+ E LE++ Q L + + E L+ + +K + KE + KL ++E+E LR ++ A EED++RL E+E E + +++ Q Q+E ++L R+ +KEEL++EI +Q+ERD+ LL AE KQ A++L E EK ++ EK+ L ++ER + + + R +QD+NT+ +L+ R Q E+ H + +K L+ L Q+ MRE EEL++ L++ E+TRD LR++L E+ K R+++D E R+E + +R+ E KE E ++ SN+ELR +K +E ++I ++ +D + KL++LEE + + KE + R +LQ+ E++R++ RREL+ELR Q+K LD++ G+L E++ LQ R+A E E E+RRE GL+Q++++ E++ E L ++L S RK +E E ++E+ +E K L +S +LE +LE EL LS E R LE ++ ++ +R+ AE +L + S LR+ +G GRVSS + E G GD + S+ PG DLDPEAVR ALRD Q + S +RERD+++++ + + E + D A R QLQK E EE + D RLS AQ L +QEE++ R++RE ++ +D++ LER L E+E + QE+V KM+ E+ E ++R L + +D +E+R +LEL RR LEGELQR ++G D+E Q L+DRVD+L +Q++D E KA +LQLT++RLS LA+ EE E + KV L +L++ +L S QDK + LQ L++ EHDR+VLQERL++ + LSEA+ Q+ +L ++++ + EL E ++ + EG++++L Q L QRQE E + + E+ LL ERL SL +LA LE+E+RD+E+ ++ +K++ +L+KTLDK+E+EK RS E + +R D E + +Q+Q L+ Q+ A + + + + E+ E++RL+SA TE+TL+ RER+HRQ+V LEEQ++ LK QL QEL++
Sbjct: 75 MASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVNERLEQAV--------RLETGELEAQEPRGLVRQSVELRRQLQEEQSSYRRKLQAYQEGQQRQAQLVQRLQAKILQY----------KKQCSELEKQL-------------MDRSTELEQQRLR--DTEHSQDLDSALLRLEEEQQRSASLAQVNAMLREQLDQANLANQALSEDIRKVTSDWTRSCKELEQREAVWRREEESFNTYFSSEHSRLLRLWRQVMGLRRQASEVKMGTERDLLQLGGELVRTSRAVQELGLGLSASLHRAESKAEAALEKQKLLQAQLEEQLQAKLLREKDLAQLQVQSDLDKADLSARVTELALSVEHLQNQNSEKDQVNRTLSDKLEALESLRLQEQTTLDTE--------------DGEGLQQTLRDLAQAALSDTESGVQLSSSERTADT------SDG------SLRGFSGQRTPTPPRHSP---------GRGRSPRRGLSPACSDSSTLTLIHSALHKRQLQVQDMRGRYEASQELLGSVRKQLSDSEGERRGLEEQLQRLRDQTAASAQAQEDAQREAQRLRSANELLSREKGNLTHSLQVTQQQAKELRQELEKLQAAQEELKRQHNQLEDAQEDSVQEGARARRELERSHRQLEQLEVKRSGLTKELVEVREALSCAILQRDVLQTEKAEVAEALTKAEAGRAQLELSLTKLRAEEASLRDSLSKMSALNESLAQDKLELNRLIAQLEEEKVALLGRQQQAEHATTMAVEKQELLEQL-RLEQEVE-----RQGLQGSLCVAEQAREALEQQILVLRSERSHLQEQLAQLSRQLSGRDQELEQALRESQRQVEALERAAREKEAMAKERAGLAVKLAAAEREGRTLSEEAIRLRLEKEALESSLFDVQRQLAQLEARREQLEADSQALLLAKETLTGELAGLRQQVTSTEEKAALDKELMTQKLVQAEREAQASLREQRAAHEEDLQRLQHEKEAAWRELQAERAQLQGQLQQEREELLARMEAEKEELSKEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAAISLEMERQKRDAQSRQEQDRNTLNALTSELRDLRAQLEEATAAHAQTVKELEERTGNLGRQREACMREAEELRTQLRVLEDTRDGLRRELLEAQRKGRDSQDSSEAHRQEASELRRSLSEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARVSVAKEAGELRASLQEVERSRLEARRELQELRRQMKTLDSDNGRLGRELADLQGRLALGERTEKESRREALGLRQRLLKGESSLEALKQELQGSQRKLQEQEAEFRARERGLLGSLEEARGAEKRLLDSARSLELRLEAVRAETSELGLRLSAAEGRAQGLEVELARVEAQRRVAEAQLGGLRSALRRGLGL--------------------------GRVSSSPAREAP-------AGGSGDGLSSPSPLEYSPRSQPPSPGLIASPAPPDLDPEAVRDALRDFLQELRSAQRERDELKVQTSTLSQQLVEMEAERDHAASRAKQLQKAVAESEEAWRSADRRLSGAQAELALQEESVRRSKRECRATLDQMAVLERSLQATESELRASQEKVSKMKATEAKLESDKRRLKEVLDASESRSIKLELQRRALEGELQRSRLGLGDREAHAQALQDRVDSLQRQVADSEVKAGTLQLTVERLSGALAKVEESEGNLRSKVQSLTDALTQSSASLSSTQDKNLHLQKALSTCEHDRQVLQERLDAARQALSEARRQSSSLGEQVQTLRGELASLELQRGDAEGQLQQLQQALRQRQEGEAMALRSVQKLQEERRLLQERLGSLQRALAQLEAEKRDLERSALQFDKDRVALRKTLDKVEREKLRSHEDTLRLNAERGRLDRTLTGAELDLAEAQQQIQHLEAQVDVALEGNHNPVQPEAGEQQLELQQEVERLRSAQVQTERTLEARERAHRQRVSGLEEQVSTLKAQLHQELRR 1995
BLAST of Rootletin-2 vs. UniProt/SwissProt
Match: sp|H7BZ55|CRCC2_HUMAN (Putative ciliary rootlet coiled-coil protein 2 OS=Homo sapiens OX=9606 GN=CROCC2 PE=5 SV=4) HSP 1 Score: 258.84 bits (660), Expect = 7.168e-68 Identity = 394/1524 (25.85%), Postives = 697/1524 (45.73%), Query Frame = 1
Query: 886 LKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLAC----SNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERM-----RHTISMLEEDKLKLDKSRMNSYE-ECKSYKQDMEK--LKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLE--TANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIE--ALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTE-----------RGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSD----LDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERR---GLIK 5355
L + + + L R++ E L+ +E + ++DLE + L+ + +S L Q+ ALLR+QL+ AN L ++ ++ L+ ELE + W + T S L G+ + LW V +++ + ER L L+ + ++ + L AC SNL + + S L QL + QL+ K + L+EQ + V E LT++ K K + L DL N + D +L + + ++ + P + S R+ SP + + H S P ++ D A+R+A+ +R + Q+L ++ S++ S+++QL +S E +K + R+ + RE Q E +R+ R + +L +K L+ M E + K+ D EK L+ ELQR + ++L ER + +E ++ E K S L+EE++S++E+L+ A L+++V+E E L +L + E A+ E+ + K+E RD + ++ L ++ S + Q E E+ +L ++K LEQE+ E+L + E + + GL Q+ +E+ E L+ + + L EK QL+ VT Q++ AL +L Q+ +D E +Q++++ K+ L++E+ L+++ E + R A+ L+ E++ L+ SL E+QQ ++L+ ++E A + L R + E ++LQ +++V+ KL + LQ ++ + E+E + L S+ A E + +L E+E L + KE + Q ++E +L + ++E L EI ++++ERD+ LL+ E Q A++L E E+ + E++S+ + LER + E + + +Q Q TI +LK + QFE H RE L+ + ++L ++ RE E L++ L +A+E LRQ+L + E+ RE L RE + +R + +E + + L N ELR + +E +K +R ++ + KL ILEE + LQ+E R +L + E+A D R+EL EL QV+ L E + + EV L+ + A E K AR+E GL++K+ E EA E ++L + LR++ E+ L + E+ + L+E+ + + L + L +RI LE ++ + R+ AE +L + S LR+ +G ++Q + SP KG S +S + R ++ S PG +D V+ LRD Q + +RERDD I+ + + E + +A R+ QLQK E EE ++ ++ LSSA+ A +Q+E + R E E + + G+ EK+ LQE+++ +R EE RR GL K
Sbjct: 117 LASRCRVVSEQLQARLETTEAQLRRSELEHSVDLEEALGRLEAAEERSTGLCQVNALLREQLEHMKKANDALGRELAGMTGSVQRLQGELELRR--WAQRQ-TRSGGL-GQPRDLLLLWRQAVVLGTDLAELRVATERGLADLQADTARTARRLHTACLNLDSNLRLSASSTASTLGQQLRDKAGEMLQLQGRWDAEKVALQA----------RLSEQTLLV----EKLTEQNEQKAKTIAALRT-------DLQNLVAQEDARCL------------------ELAGSSITELGE-------------------PRRPLRS--PQRATSPHQGASPPHICS-------------PATL-DPALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELWAAQK-LQQERAREQAREREALRGQLEAQRLEVQQCRASCKLLGREKAALE---MVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQ--ALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGL-----ARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQE-KELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSR-------ARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQEL-------QGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRESRGAEQTLRA----------ELHSVTRKLQEA-----------SGVADALQARLDQACHRIHSLEQELAQAEGARQDAEAQLGRLCSTLRRGLGLQRQ---------SPWASPEQPGSPTKG---SDSSQALPGQQGTSPPARPHSPLRWP-SPTPGGRSSELMDVATVQDILRDFVQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARAARALQKEALRRLELEHLASVRAAGQ----------EKRRLQEQLETLR---QALEESRRHSQGLAK 1489 HSP 2 Score: 63.5438 bits (153), Expect = 2.824e-8 Identity = 35/83 (42.17%), Postives = 57/83 (68.67%), Query Frame = 1
Query: 6193 RQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRE 6441
RQ Q+LQ Q+ E EQ H QR+ +LT++ + ++ +E +RL A + L+ +E +H+Q+VK LEEQ+ LK+QL QE++ R+
Sbjct: 1555 RQNQQLQAQMTEMEQAHTQRLQDLTAQHQRDLATEAERLHGARPQATQALESQEWTHQQQVKVLEEQVASLKEQLDQEVQWRQ 1637
BLAST of Rootletin-2 vs. UniProt/SwissProt
Match: sp|Q9BV73|CP250_HUMAN (Centrosome-associated protein CEP250 OS=Homo sapiens OX=9606 GN=CEP250 PE=1 SV=2) HSP 1 Score: 172.94 bits (437), Expect = 1.956e-41 Identity = 291/1208 (24.09%), Postives = 555/1208 (45.94%), Query Frame = 1
Query: 685 QTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNL-------DTNHVNRL-----SQLQF------QLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNE---SLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQ-------EIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELE------TIQLSNKELR----EKLKTSEMQKIDIQRQ-LQDLQNKLSILEEQKQVLQKEVKD 4191
Q + L++Q+ ++ RKL + Q +QA L+++LQ K+ Q RS L+ + T + +R + E + N+D ++ L+EEQ + SL ++ LR +++A N+ L EDV++L+ + S + EL +K+ W+ ++ F +L GE R+ SLW VV F+R F ++KS+ +RDL +L+ + + SL C L + N R+ +QL +L+ E + SQ L ++K + + + Q ++ L+ + NE + K L + ++L T H + ++ S +R + ++ Q ++DI Q+++ + D + ++ +G NSL + S+ S F+ Y++ AD VRS L +R VQDL ++ + N +++Q D E E + L ++ +L E D+ + D+Q E + L +++ L K+R ++ + +Q+ +L+ +N ELQ ++ ++ L +E ERL + + E+K S E+ +L+E+L + LE E+L QE + +T +L + E AE N KTE A LR +L ++N L + + Q E E + +A EQ + ++ +L E +E L + L +Q E++ LQ +L + EK +++ + ++ A +T+L Q ++A+R + +++++KE L +EK L +L E + ++ A+ + L KE L+ SL+E+QQ S +E LE +Q + + + +I E + L+ E D E + + +++ +L ++E+E L +K A E+++ +L K+++E + Q+E+ L R+K EL E+ IQ +R++ +AE E+E++S+ E + Q L + LER R + +++ ++Q T L++ + + ++ H ++ LQ L K ++ E+LKS L ++++ + Q++ E K+RET++ Y ++KELE T+ L KE R ++ + Q++ RQ +Q+ Q + L Q ++L++EVK+
Sbjct: 23 QVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQAKVLQY-----------------RSWCQELEKRLEATGGPIPQRWENVE--------EPNLD--ELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQ---ELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNH-----------TELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNI-------------AQGSGH------ENSLELDSSIF-------SQFD---------YQD------ADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGE-------VDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLRE----------KWEKE-RSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQE---KLRETQE---------------YNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKE 1112
BLAST of Rootletin-2 vs. UniProt/SwissProt
Match: sp|Q8IVE0|CROL2_HUMAN (Putative ciliary rootlet coiled-coil protein-like 2 protein OS=Homo sapiens OX=9606 GN=CROCCP3 PE=5 SV=1) HSP 1 Score: 84.7297 bits (208), Expect = 4.750e-16 Identity = 60/184 (32.61%), Postives = 107/184 (58.15%), Query Frame = 1
Query: 2050 NSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTE---VLKAEYEVKANKFKTE 2592
+++KQL DSE+ERR LE+Q LR + DS + +D QRE +R+R +L +K L S + ++ K +Q+ +KL+ EL+R + L + +D ++ R +E+ER + +E E K S L +E+ ++E+L+RA L++++L+ E + + ++L K E L A V+A + + E
Sbjct: 13 GTLRKQLSDSESERRALEEQLQRLRDKTDSTMQAHEDAQREVQRLRSAKELLRREKSNLAHSLQVAQQQAKELRQERKKLQAAQEELRRQRYWLGEEQEDAVQDGVRVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEGRGGLPAGLPVQAERPQRE 196
BLAST of Rootletin-2 vs. TrEMBL
Match: A0A481MTJ1 (Rootletin-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 4162.45 bits (10794), Expect = 0.000e+0 Identity = 2190/2203 (99.41%), Postives = 2191/2203 (99.46%), Query Frame = 1
Query: 109 MSSANRDERLEQVAQKLNKFTDIFYQRVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA 6717
MSSANRDERLEQVAQ RVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVSNASEELSNANSLASQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQ+KLNESEKEWNKILRSEKEAREEDIERLIAEREELRNEFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVRRELEELRSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLRNRSPSPGRRSRSVSPEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTQLELLRRGLEGELQRLKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSLKKTLDKLEKEKNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNN NVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA
Sbjct: 1 MSSANRDERLEQVAQ-----------RVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVSNASEELSNANSLASQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQMKLNESEKEWNKILRSEKEAREEDIERLIAEREELRNEFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVRRELEELRSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLRNRSPSPGRRSRSVSPEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTQLELLRRGLEGELQRLKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSLKKTLDKLEKEKNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNSNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA 2192
BLAST of Rootletin-2 vs. TrEMBL
Match: A0A267H6I3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018782g1 PE=4 SV=1) HSP 1 Score: 1256.89 bits (3251), Expect = 0.000e+0 Identity = 842/2042 (41.23%), Postives = 1283/2042 (62.83%), Query Frame = 1
Query: 691 IQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSA-ETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNS--------IYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGS-------------------------DLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISK-TSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPT 6711
+ LRK+LDD+ + YKRKLA + Q +QA+L+++LQ K+ + + V + + +N +L++++ F+ + ++D +E L+S + D + DLES + L+EEQ +S SL + A+LR+QLD+AT NQ LTED++RLSE+ +S+LE+++ +W+D+EA+FS + E NR+ SLW +V+F+RQFN++K++NERDL+ + + + ++ + AC NL+ N + +Q LD E++ + LE++L + E + + +++ L+ + ++ NE L +LA+K++ L+ L +LR+ G S DD+ATR LI +T+A+HQ+LRDIAQ V++D D D + D + RSVSP RS R++SP + ADST +AV++AL+KRALQVQ+L K+ SAK+ +++++QLD+SENERR LE Q + LR E D+ R D R+ ER++ ++ E+++ +L+K R E+ +S D+++L+ N ELQR ++ L D D ++L+RQ KE ER + I+ E K S LK ++ KE+LNRA LEKEVL+QE + ++D+L+++E+ KAE E++ NK K+EEA LRD +++S+N L + E I+ E+EK +LSGEK+ALEQEKYGIREEL+R E EK EL+ K GL+Q+++ E S E L+DEL +N E+ +L + R++ AL+ ELL +RR+ ER S V + K+KE L KEK +L+ QLT E E+R + L+ +K+QL+ +L+E+Q+ I QLE + LE Q+L K+ + E R+ EF+VE KL++ +E+LQ K+ + E++ L E+++ E+D+ERL E++ R E+ ++E Q E +++ R++E+L EI QRERD+ L+ AE KQ A++++EQEK ++ E++ L+T S+L+R R E + QQD+ TI + NG+LKKFR QFEQ +H+ E++ L EL Q+ RE ELK L++AE+ RDNLR++L ++ +IRE E+ + +RE+ + KR E + E ++ SN+ELR+K+K E ++I+ R + + + ++ +LEEQK L KEV D R NL++ EKARV+ +REL+ELR QVK LDTERGKL EV LQ RVA DE K+ E RRENFGLKQKV+E+EA++E L K+L S R+ +LEE L SK++ +E K+ + L++++ L+ +E + EL L E RI+ LE + D +K E +LA+IHS +R+LIGFRQ ++ R SP R S NS F + F + S IP S D+DPEAVR+ALRD Q +V+ ERERDD A++ + E + QR QL +N E EEDKKGID RL+SAQTALM+QEETI RNERE+K+L DK+ LERQ++ +ETEK+ LQE+++KM+ ++ EE+++ L +++DD ENRCTQLEL +R LEG++QR+++ DK+ ENQVL DRVD L KQI+DLESKAQSLQLTI+RLS++LA+TEE+ + QKD+V QLN S+S+ + S+Q+++ QLQ L SSEHDRRVLQERL++ L+EAK QNH L++R+++ Q EL ++E R++++EG ++ + +L+Q+QE EQEL K++++ E+ + ER+ SL +LAGLE+E+++IEK + EK+K +LKKTLDK+E+E+ R+EE+ ++S R E D RRLE+ENE L RQVQ LQ+ LAEAEQ H+QR+M+L ++ + E +E++RLK+ + E+TL+ RER HRQ+VK LEEQ+ LKDQL+QE+++R L+KS RG D+ DI++IL+ + +S+ D L++ E RR+ + L +N K++ P + R + S P
Sbjct: 31 MDLRKRLDDEQQSYKRKLATYQEGQQRQAQLVQKLQAKVLAYKKK---VSESDLENQRLKTQL----RSFKQSNDSYQFKLD-SETRLRSGGDEDHSSDLESALIRLEEEQQRSASLAHVNAMLREQLDQATQVNQSLTEDMKRLSEDFQRTRSDLERRESEWRDEEASFSEYFSSEHNRLLSLWRNLVSFRRQFNELKTANERDLNNFKNEMTRQSRGVHAACQNLNANLKSAETQGAVALDQERSGRANLESALRERTRELQDLQAKFEAHQADLSGRVNELSVQNEKLKFQLAEKDRTLSHLQRLRSSGGGGGGGSASRSQSAEPPGADDAATRALIEETEAMHQSLRDIAQAVISDADGYRD-------FSDAGR----------------GRSVSPVGRGGRSPAGR--------QRSRSP-AFADSTYSAVQAALNKRALQVQELRGKLASAKDAGDNIRRQLDESENERRRLEHQVLGLREELDTVQRAQTDSGRDYERLKSALTAREQERSQLEKVRSALNEQIESLHADLDRLQQANSELQRCRDCLEDQKADQKKDLDRQVKENERCQRCIDQLEEKLSNLKSDLVQTKENLNRACLEKEVLDQEKAEVSDALSRSELAKAELELELNKMKSEEAALRDALLKMQSLNEGLGHDKVELNKILMMYENEKAQLSGEKQALEQEKYGIREELLRCEQEKMELDNEKAGLYQTLELSEMSREKLEDELQSINRERLELAEQLNAIGRQKRALAEELLASRRETERASNTVLRVAKEKEDLTKEKGELVVQLTACEREIRRLGELASGLRADKDQLEDALHEAQELIVQLETRKGQLEGENQELIIKKENLTAEISRITKEFEVECDKLTRQRENLQQKMQQMERDLKHALAQEQQSHEDDLERLTKEKDNQRAEYENQRQETIHQNNMEREEMVSSFEREREQLHTEIAACQRERDESLMLAENDKQQALSIVEQEKSTILERLGNTHAELQTVASELDRARREAAAKQQQDKETINSLNGELKKFRDQFEQTVEEHEAEVRKLNEQINELTQQREAACREVAELKVQLRMAEDARDNLRRELIDANRRIREQEEALDAQKREIFELKRQLAEEGRAREAVEKSNEELRKKIKEMEAERIERDRSIAEQKQRIGVLEEQKAALGKEVADLRGNLREVEKARVEAKRELQELRRQVKMLDTERGKLCKEVCDLQSRVAHDEEKDEENRRENFGLKQKVVETEASREALRKELGNSKRREADLEEELRSKQRDFALAMEEARKELRRLDDARSELQLSVEAASAENNELRQALGGAEGRINALETTLARTDSVKKELEYKLASIHSSMRRLIGFRQDNPRS--------PSPMRGRSPSPARRSRPNSPTKGFDGSQP----FATTAEGRGSPIPRSGSPAARGRSPFRSGSPSRGDIANACDIDPEAVRLALRDFVQQLVNTERERDDALAAARSLEQRVAEMEEAAQRNEQRTQQLHRNLCETEEDKKGIDGRLASAQTALMLQEETIRRNEREKKALGDKMSGLERQISGLETEKRQLQEKLNKMKQHDARQEEDKKNLKRSLDDVENRCTQLELTKRALEGDMQRMRLALGDKDAENQVLHDRVDNLNKQIADLESKAQSLQLTIERLSVSLAKTEEDGSQQKDRVQQLNGSVSDMAATIDSLQERVGQLQKALTSSEHDRRVLQERLDNTHAALNEAKHQNHQLLERVQSLQGELTDNEHRRNDLEGSNRQTNSLLAQKQEAEQELTQKLNKANQERAAMQERVQSLQRALAGLENEKKEIEKSASRLEKDKTALKKTLDKVERERIRTEEAASKSAFARGELDSALRRLEEENEALQRQVQALQSHLAEAEQAHSQRLMDLGAKHREETDTELERLKAGQLAAERTLENRERLHRQRVKGLEEQVATLKDQLAQEVRRRNQFLSKSARGAAGDLSDIRTILDSSLGTVSRDPGLDAALFDAESRRLDEALD----LHNAFPGGAGKRAGSPSRLGGAGGALRSSTPSGRPA 2016
BLAST of Rootletin-2 vs. TrEMBL
Match: A0A1I8FWZ5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 1251.11 bits (3236), Expect = 0.000e+0 Identity = 875/2236 (39.13%), Postives = 1343/2236 (60.06%), Query Frame = 1
Query: 109 MSSANRDERLEQVAQKLNKFTDIFYQRVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSA-ETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNS--------IYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGS-------------------------DLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISK-TSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPT 6711
M+S RD++LE+V +L ++VL + + GYL+ G GG + ++ ++D I R+ D + D + D V +L+ E L +EE L + ERD L+I++NA++E+ ++ + G R + + LRK+LDD+ + YKRKLA + Q +QA+L+++LQ K+ + + V + + +N +L++++ F+ + ++D +E L+S + D + DLES + L+EEQ +S SL + A+LR+QLD+AT NQ LTED++RLSE+ +S+LE+++ +W+D+EA+FS + E NR+ SLW +V+F+RQFN++K++NERDL+ + + + ++ + AC NL+ N + +Q LD E++ + LE++L + E + + +++ L+ + ++ NE L +LA+K++ L+ L +LR+ G S DD+ATR LI +T+A+HQ+LRDIAQ V++D D D + D + RSVSP RS R++SP + ADST +AV++AL+KRALQVQ+L K+ SAK+ +++++QLD+SENERR LE Q + LR E D+ R D R+ ER++ ++ E+++ +L+K R E+ +S D+++L+ N ELQR ++ L D D ++L+RQ KE ER + I+ E K S LK ++ KE+LNRA LEKEVL+QE + ++D+L+++E+ KAE E++ NK K+EEA LRD +++S+N L + E I+ E+EK +LSGEK+ALEQEKYGIREEL+R E EK EL+ K GL+Q+++ E S E L+DEL +N E+ +L + R++ AL+ ELL +RR+ ER S V + K+KE L KEK +L+ QLT E E+R + L+ +K+QL+ +L+E+Q+ I QLE + LE Q+L K+ + E R+ EF+VE KL++ +E+LQ K+ + E++ L E+++ E+D+ERL E++ R E+ ++E+ Q E +++ R++E+L EI QRERD+ L+ AE KQ A++++EQEK ++ E++ L+T S+L+R R E + QQD+ TI + NG+LKKFR QFEQ +H+ E++ L EL Q+ RE ELK L++AE+ RDNLR++L ++ +IRE E+ + +RE+ + KR E + E ++ SN+ELR+K ++ +LEEQK L KEV D R NL++ EKARV+ +REL+ELR QVK LDTERGKL EV LQ RVA DE K+ E RRENFGLKQKV+E+EA++E L K+L S R+ +LEE L SK++ ++ K+ + L++++ L+ +E + EL L E RI+ LE + D +K E +LA+IHS +R+LIGFRQ ++ R SP R S NS F + F + S IP S D+DPEAVR+ALRD Q +V+ ERERDD A++ + E + QR QL +N E EEDKKGID RL+SAQTALM+QEETI RNERE+K+L DK+ LERQ++ +ETEK+ LQE+++KM+ ++ EE+++ L +++DD ENRCTQLEL +R LEG+LQR+++ DK+ ENQVL DRVD L KQI+DLESKAQSLQLTI+RLS++LA+TEE+ + QKD+V QLN S+S+ + S+Q+++ QLQ L SSEHDRRVLQERL++ ++EAK QNH L++R+++ Q EL ++E R++++E ++ + +L+Q+QE EQEL K++++ E+ + ER+ SL +LAGLE+E+++IEK + EK+K +LKKTLDK+E+E+ R+EE+ ++S R E D RRLE+ENE L RQVQ LQ+ LAEAEQ H+QR+M+L ++ + E +E++RLK+ + E+TL+ RER HRQ+VK LEEQ+ LKDQL+QE+++R L+KS RG D+ DI++IL+ + +S+ D L++ E RR+ + L +N K++ P + R + S P
Sbjct: 1 MTSGERDQKLEKVIHRLE----------QSVLKEGQSGGYLRT-----------GTGGRE--------RVSARIRDSITRNLDDPVGTGSGVADWSGVGGRVGSGGGVGSG-------DEVARLQRE-------LNRLEEALADTRAERDQLSIRYNALSERQHED-PGDDPGSRGLMQM-------------NMDLRKRLDDEQQSYKRKLATYQEGQQRQAQLVQKLQAKVLAYKKK---VSESDLENQRLKTQL----RSFKQSNDSYQFKLD-SETRLRSGGDEDHSSDLESALIRLEEEQQRSASLAHVNAMLREQLDQATQVNQSLTEDMKRLSEDFQRTRSDLERRESEWRDEEASFSEYFSSEHNRLLSLWRNLVSFRRQFNELKTANERDLNNFKNEMTRQSRGVHAACQNLNANLKSAETQGAVALDQERSGRANLESALRERTRELQDLQAKFEAHQADLSGRVNELSVQNEKLKFQLAEKDRTLSHLQRLRSSGGGGGGGSASRSQSAEPPGADDAATRALIEETEAMHQSLRDIAQAVISDADGYRD-------FSDAGR----------------GRSVSPVGRGGRSPAGR--------QRSRSP-AFADSTYSAVQAALNKRALQVQELRGKLASAKDAGDNIRRQLDESENERRRLEHQVLGLREELDTVQRAQTDSGRDYERLKSALTAREQERSQLEKVRSALNEQIESLHADLDRLQQANSELQRCRDCLEDQKADQKKDLDRQVKENERCQRCIDQLEEKLSNLKSDLVQTKENLNRACLEKEVLDQEKAEVSDALSRSELAKAELELELNKMKSEEAALRDALLKMQSLNEGLGHDKVELNKILMMYENEKAQLSGEKQALEQEKYGIREELLRCEQEKMELDNEKAGLYQTLELSEMSREKLEDELQSINRERLELAEQLNAIGRQKRALAEELLASRRETERASNTVLRVAKEKEDLTKEKGELVVQLTACEREIRRLGELASGLRADKDQLEDALHEAQELIVQLETRKGQLEGENQELIIKKENLNAEISRITKEFEVECDKLTRQRENLQQKMQQMERDLKHALAQEQQSHEDDLERLTKEKDNQRAEYENQRQEMIHQNNMEREEMVSSFEREREQLHTEIAACQRERDESLMLAENDKQQALSIVEQEKSTILERLGNTHAELQTVASELDRARREAAAKQQQDKETINSLNGELKKFRDQFEQTVEEHEAEVRKLNEQINELTQQREAACREVAELKVQLRMAEDARDNLRRELIDANRRIREQEEALDAQKREIFELKRQLAEEGRAREAVEKSNEELRKK--------------------RIGVLEEQKAALGKEVADLRGNLREVEKARVEAKRELQELRRQVKMLDTERGKLCKEVCDLQSRVAHDEEKDEENRRENFGLKQKVVETEASREALRKELGNSKRREADLEEELRSKQRDFALAMEDARKELRRLDDARSELQLSVEAASAENNELRQALGGAEGRINALETTLARTDSVKKELEYKLASIHSSMRRLIGFRQDNPRS--------PSPMRGRSPSPARRSRPNSPTKGFDGSQP----FATTAEGRGSPIPRSGSPAARGRSPFRSGSPSRGDIANACDIDPEAVRLALRDFVQQLVNTERERDDALAAARSLEQRVAEMEEAAQRNEQRTQQLHRNLCETEEDKKGIDGRLASAQTALMLQEETIRRNEREKKALGDKMSGLERQISGLETEKRQLQEKLNKMKQHDARQEEDKKNLKRSLDDVENRCTQLELTKRALEGDLQRMRLALGDKDAENQVLHDRVDNLNKQIADLESKAQSLQLTIERLSVSLAKTEEDGSQQKDRVQQLNGSVSDMAATIDSLQERVGQLQKALTSSEHDRRVLQERLDNTHAAMNEAKHQNHQLLERVQSLQGELTDNEHRRNDLEDSNRQTNSLLAQKQEAEQELTQKLNKANQERAAMQERVQSLQRALAGLENEKKEIEKSASRLEKDKTALKKTLDKVERERIRTEEAASKSAFARGELDSALRRLEEENEALQRQVQALQSHLAEAEQAHSQRLMDLGAKHREETDTELERLKAGQLAAERTLENRERLHRQRVKGLEEQVATLKDQLAQEVRRRNQFLSKSARGAAGDLSDIRTILDSSLGTVSRDPGLDAALFDAESRRLDEALD----LHNAFPGGAGKRAGSPSRLGGAGGALRSSTPSGRPA 2103
BLAST of Rootletin-2 vs. TrEMBL
Match: A0A267F2Q1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001435g3 PE=4 SV=1) HSP 1 Score: 1249.96 bits (3233), Expect = 0.000e+0 Identity = 840/2042 (41.14%), Postives = 1283/2042 (62.83%), Query Frame = 1
Query: 691 IQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSA-ETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNS--------IYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGS-------------------------DLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISK-TSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPT 6711
+ LRK+LDD+ + YKRKLA + Q +QA+L+++LQ K+ + + V + + +N +L++++ F+ + ++D +E L+S + D + DLES + L+EEQ +S SL + A+LR+QLD+AT NQ LTED++RLSE+ +S+LE+++ +W+D+EA+FS + E NR+ SLW +V+F+RQFN++K++NERDL+ + + + ++ + AC NL+ N + +Q LD E++ + LE++L + E + + +++ L+ + ++ NE L +LA+K++ L+ L +LR+ G S DD+ATR LI +T+A+HQ+LRDIAQ V++D D D + D + RSVSP RS R++SP + ADST +AV++AL+KRALQVQ+L K+ SAK+ +++++QLD+SENERR LE Q + LR E D+ R D R+ ER++ ++ E+++ +L+K R E+ +S D+++L+ N ELQR ++ L D D ++L+RQ KE ER + I+ E K S LK ++ KE+LNRA LEKEVL+QE + ++D+L+++E+ KAE E++ NK K+EEA LRD +++S+N L + E I+ E+EK +LSGEK+ALEQEKYGIREEL+R E EK EL+ K GL+Q+++ E S E L+DEL +N E+ +L + R++ AL+ ELL +RR+ ER S V + K+KE L KEK +L+ QLT E E+R + L+ +K+QL+ +L+E+Q+ I QLE + LE Q+L K+ + E R+ EF+VE KL++ +E+LQ K+ + E++ L E+++ E+D+ERL E++ R E+ ++E+ Q E +++ R++E+L EI QRERD+ L+ AE KQ A++++EQEK ++ E++ L+T S+L+R R E + QQD+ TI + NG+LKKFR QFEQ +H+ E++ L EL Q+ RE ELK L++AE+ RDNLR++L ++ +IRE E+ + +RE+ + KR E + E ++ SN+ELR+K+K E ++I+ R + + + ++ +LEEQK L KEV D R NL++ EKARV+ +REL+ELR QVK LDTERGKL EV LQ RVA DE K+ E RRENFGLKQKV+E+EA++E L K+L S R+ +LEE L SK++ ++ K+ + L++++ L+ +E + EL L E RI+ LE + D +K E +LA+IHS +R+LIGFRQ ++ R SP R S NS F + F + S IP S D+DPEAVR+ALRD Q +V+ ERERDD A++ + E + QR QL +N E EEDKKGID RL+SAQTALM+QEETI RNERE+K+L DK+ LERQ++ +ETEK+ LQE+++KM+ ++ EE+++ L +++DD ENRCTQLEL +R LEG+LQR+++ DK+ ENQVL DRVD L KQI+DLESKAQSLQLTI+RLS++LA+TEE+ + QKD+V QLN S+S+ + S+Q+++ QLQ L SSEHDRRVLQERL++ ++EAK QNH L++R+++ Q EL ++E R++++E ++ + +L+Q+QE EQEL K++++ E+ + ER+ SL +LAGLE+E+++IEK + EK+K +LKKTLDK+E+E+ R+EE+ ++S R E D RRLE+ENE L RQVQ LQ+ LAEAEQ H+QR+M+L ++ + E +E++RLK+ + E+TL+ RER HRQ+VK LEEQ+ LKDQL+QE+++R L+KS RG D+ DI++IL+ + +S+ D L++ E RR+ + L +N K++ P + R + S P
Sbjct: 31 MDLRKRLDDEQQSYKRKLATYQEGQQRQAQLVQKLQAKVLAYKKK---VSESDLENQRLKTQL----RSFKQSNDSYQFKLD-SETRLRSGGDEDHSSDLESALIRLEEEQQRSASLAHVNAMLREQLDQATQVNQSLTEDMKRLSEDFQRTRSDLERRESEWRDEEASFSEYFSSEHNRLLSLWRNLVSFRRQFNELKTANERDLNNFKNEMTRQSRGVHAACQNLNANLKSAETQGAVALDQERSGRANLESALRERTRELQDLQAKFEAHQADLSGRVNELSVQNEKLKFQLAEKDRTLSHLQRLRSSGGGGGGGSASRSQSAEPPGADDAATRALIEETEAMHQSLRDIAQAVISDADGYRD-------FSDAGR----------------GRSVSPVGRGGRSPAGR--------QRSRSP-AFADSTYSAVQAALNKRALQVQELRGKLASAKDAGDNIRRQLDESENERRRLEHQVLGLREELDTVQRAQTDSGRDYERLKSALTAREQERSQLEKVRSALNEQIESLHADLDRLQQANSELQRCRDCLEDQKADQKKDLDRQVKENERCQRCIDQLEEKLSNLKSDLVQTKENLNRACLEKEVLDQEKAEVSDALSRSELAKAELELELNKMKSEEAALRDALLKMQSLNEGLGHDKVELNKILMMYENEKAQLSGEKQALEQEKYGIREELLRCEQEKMELDNEKAGLYQTLELSEMSREKLEDELQSINRERLELAEQLNAIGRQKRALAEELLASRRETERASNTVLRVAKEKEDLTKEKGELVVQLTACEREIRRLGELASGLRADKDQLEDALHEAQELIVQLETRKGQLEGENQELIIKKENLNAEISRITKEFEVECDKLTRQRENLQQKMQQMERDLKHALAQEQQSHEDDLERLTKEKDNQRAEYENQRQEMIHQNNMEREEMVSSFEREREQLHTEIAACQRERDESLMLAENDKQQALSIVEQEKSTILERLGNTHAELQTVASELDRARREAAAKQQQDKETINSLNGELKKFRDQFEQTVEEHEAEVRKLNEQINELTQQREAACREVAELKVQLRMAEDARDNLRRELIDANRRIREQEEALDAQKREIFELKRQLAEEGRAREAVEKSNEELRKKIKEMEAERIERDRSIAEQKQRIGVLEEQKAALGKEVADLRGNLREVEKARVEAKRELQELRRQVKMLDTERGKLCKEVCDLQSRVAHDEEKDEENRRENFGLKQKVVETEASREALRKELGNSKRREADLEEELRSKQRDFALAMEDARKELRRLDDARSELQLSVEAASAENNELRQALGGAEGRINALETTLARTDSVKKELEYKLASIHSSMRRLIGFRQDNPRS--------PSPMRGRSPSPARRSRPNSPTKGFDGSQP----FATTAEGRGSPIPRSGSPAARGRSPFRSGSPSRGDIANACDIDPEAVRLALRDFVQQLVNTERERDDALAAARSLEQRVAEMEEAAQRNEQRTQQLHRNLCETEEDKKGIDGRLASAQTALMLQEETIRRNEREKKALGDKMSGLERQISGLETEKRQLQEKLNKMKQHDARQEEDKKNLKRSLDDVENRCTQLELTKRALEGDLQRMRLALGDKDAENQVLHDRVDNLNKQIADLESKAQSLQLTIERLSVSLAKTEEDGSQQKDRVQQLNGSVSDMAATIDSLQERVGQLQKALTSSEHDRRVLQERLDNTHAAMNEAKHQNHQLLERVQSLQGELTDNEHRRNDLEDSNRQTNSLLAQKQEAEQELTQKLNKANQERAAMQERVQSLQRALAGLENEKKEIEKSASRLEKDKTALKKTLDKVERERIRTEEAASKSAFARGELDSALRRLEEENEALQRQVQALQSHLAEAEQAHSQRLMDLGAKHREETDTELERLKAGQLAAERTLENRERLHRQRVKGLEEQVATLKDQLAQEVRRRNQFLSKSARGAAGDLSDIRTILDSSLGTVSRDPGLDAALFDAESRRLDEALD----LHNAFPGGAGKRAGSPSRLGGAGGALRSSTPSGRPA 2016
BLAST of Rootletin-2 vs. TrEMBL
Match: A0A1S3JC29 (rootletin-like isoform X4 OS=Lingula unguis OX=7574 GN=LOC106171578 PE=4 SV=1) HSP 1 Score: 1242.64 bits (3214), Expect = 0.000e+0 Identity = 851/2028 (41.96%), Postives = 1307/2028 (64.45%), Query Frame = 1
Query: 685 QTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDD---SATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTR-PSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXX---XXXXXXEKG-------RVSSRNS-VEFNFSEDRKR--VGRFGDVNQYS-ESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISK-TSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPT 6711
Q ++LR++L+++H YKRKL A D Q +QA+L+++LQ K+ Q + + G +L QNS+ +SE ++K Q+T L R++ E L+ AE D +MDLE+ + +L+EEQ +S SL + ++LR+QLD+AT+ANQ LT+D+ RL+ + + ELEQK+ +W+D+E +F+ + E +R+ SLW AVV F+RQF ++KS+ ERDL +R ++ ++++S+ AC NL N + +Q Q D ++++ + LEN L E + +T++ LN + + NE L +L +K+K ++TL + ++ + + A++ + +T+A+H ALRDIAQ V++D DQ DE +T +L RS+SP+R P R+ S S R SP + ADST +AV++AL+KR LQVQ++ +K N++K+ + +++KQLDD+ENERR +E+Q +E R E D+ R+ +D R+ +R ++ + + +K +L++ R E+ ++ + EKL+ N E+QR ++N+ D D+ ++ ERQ KE ER K IE E K S+L+E+ KE+L+++ L+K+VLE E + + ++L+K E+ AE E+ NK KTEEA LRD +++++N L ++ E II Q E+EK L GEK A+ EK GI+EEL+RVE EK +L+ K GL+Q+++ E++ ENLQ+E++ LN EK ++ ++ R+++AL+ ELLQ+R++ ER S V + K+KE L KEK LI QLT+ E E R+ ++ I + +KE L+ +LYE+QQ +QLE + E LE Q+L ++ + E RL+ E ++E++KL + KES+ KL ++E++ N L EK+A EEDIERL E+E R E+ +EEI E +++ R +KE+L QE+ IQRERDD +L AE KQ ++L+EQEK ++ EK++ L++ + ER + E R + D+N+I +LKKFR QFE+ + DRE+K+L +EL+ QK Q +RE ELK LK+ EETRD +R+DL E+ KIRE ++ +E +R+E+ D KR+ + +E E +Q +N+ELR K+K +E +KI++ R LQ+ + ++ ILEEQK +QKE D R +L++ EKAR+D RREL+ELR QVK LD+ER KL EV LQ RVA DE KE E+RRE +GLKQKV+E+EA++E L K+L R+ ELE+ KEK + ++ ++ + LEE + NLE LE N+ EL LS E R++ LE Q+ ++ ++ E +L++IHS LR+ IGFRQ + ++ + +R SP KG R S + S DR R R D++ + + +D+DPEAVRIALRD Q + ERERDD + ++ +++ E D+ R+ QLQK+ GE EEDK+GIDSRL+SAQTALM+QEETI RNERERK++ +K+ LER LA +E+EK+ LQERV KM+ E+ EE+++ L A+DD+E RCT+ EL +R +EG+LQRLK+ NDKETENQVL++R+D LT+Q+ DL+SK QSLQLTIDRLS L++TEEEE+ QKDKV LN+SLSE + +Q+++ QLQ L SSEHDRRVLQERL++ + +EAK QNH+L++R++A Q EL +SE R++E+EG++++ I+ QRQE EQEL ++ + EK L ER+ SL A LE+++R+IE+ I+TEK+K++LKKTLDK+E+EK ++EE ++S+ ++ + +RLE+EN L RQ+Q +Q Q+AE EQ H+QR+++LT+R ++E E +RL+SA E+TL+ RER+HRQ+VK LEEQIN LKDQL+QE++KR+ + +S R +DI DI++IL+ + +++ D LL + E ++ D + ++ + IS + S R S +S S R +++P
Sbjct: 44 QNVELRRKLEEEHASYKRKLQAYQDGQQRQAQLVQKLQAKVLQYKKKCG---ELEAQNSQFKSESQQVKRSLQSTQDVLQSRLETTEARLRMAEEDASMDLETALIKLEEEQQRSSSLAHVNSMLREQLDQATSANQQLTQDIHRLTTDWQRAREELEQKESEWRDEEQSFNEYFSAEHSRLLSLWRAVVAFRRQFGEMKSATERDLSHIRADLTRTSRSMHSACLNLSANLRSMDTQSQVSADRDRSDRNALENQLRDKVREVMELQTKFDIHTSELNSKVNELTMMNEKLKIQLIEKDKSISTLQANMDRVDAGRMEAARERESMEVEASQTMREETEALHAALRDIAQAVISDADQ--------SKLEDEGASTAELA-----------RSMSPSRSPRMRTRTRSASPSR-------SP-AFADSTFSAVQAALNKRQLQVQEMRAKFNASKDQNAALRKQLDDTENERRRIERQMMEYREELDNARRDKEDSFRDRDRFKNQLDLTGSEKSQLERMRQALNEQIEALNTENEKLQAANSEIQRQRDNIEDEKDDVIKDKERQIKENERCHKVIEQLEMKLSKLREDFVETKETLHKSQLDKDVLENEKAEMGEALSKAELRMAELELAVNKLKTEEAGLRDALLKMQALNEGLGQDKIELNKIIMQLEAEKASLFGEKHAIIAEKSGIQEELVRVEQEKMDLDTEKLGLNQTVEIHEQTVENLQEEITILNREKVEITEQLNSVSRQKSALAEELLQSRKECERQSDTVVRIAKEKEDLTKEKASLIVQLTSSERENRQQSEIIAGFKADKESLENALYEAQQLNAQLETRKEQLEGENQELILRKEALQAEIARLRKEMELEIEKLERQKESITAKLGQTERDLNVSLTQEKQAHEEDIERLTREKETQRIEYEANREEILHHNAMEKEEMIARAENEKEQLQQELAAIQRERDDSMLFAENEKQQVLSLMEQEKSTLAEKLNSTQKDLQSQIVENERLKRESMSRQESDKNSINGLQAELKKFRSQFEEATVAQDRELKDLNGRMQELQRQKEQALREVAELKVQLKMVEETRDTIRRDLIEANRKIREADETKELMRKEIGDLKRSVNDEVREKEAVQKANEELRNKIKRAEGEKIELSRNLQEAKQRIGILEEQKTGVQKEASDLRASLREVEKARLDARRELQELRRQVKMLDSERSKLGKEVGDLQNRVARDEEKEEESRREQYGLKQKVVETEASREALRKELANLQRRYAELEDESRVKEKDYQMALEDSRRNERKLEEIRRNLETNLEACNNEIGELKLALSGAEGRVNALEAQLARVEGAKRDVEFKLSSIHSTLRRTIGFRQDMPRSPSPTMRARSPSPRRTRPTSPAKGFDNTFTTTTDGRGSPIARTGSPDRARSPTRRERDMSPSRLDQSVSIADIDPEAVRIALRDFVQQLAGSERERDDCLSQVRSLSMQLKEMEEDRDRTEARLQQLQKSLGEAEEDKRGIDSRLASAQTALMLQEETIRRNERERKTMAEKINTLERGLAAMESEKRQLQERVGKMKQNEAKLEEDKKQLRMALDDSEQRCTKTELAKRSMEGDLQRLKLAMNDKETENQVLQERIDNLTRQMQDLDSKCQSLQLTIDRLSNALSKTEEEESVQKDKVQVLNMSLSEQSATIADLQERVQQLQRALTSSEHDRRVLQERLDTTRQAQNEAKKQNHSLMERVQAIQNELSDSEVRRNELEGQVRQAHGIIVQRQEQEQELNQRLQKLGTEKQGLQERVASLQRQYAQLETDKREIERNVIRTEKDKSALKKTLDKVEREKMKTEEVASRSMTEKGSMEGTLKRLEEENMDLQRQLQSMQAQMAEMEQAHSQRLIDLTTRHRSETEMETERLRSAQLQAERTLEARERAHRQRVKGLEEQINTLKDQLAQEMRKRQQFIQRSTRT-GDDIKDIRNILDSSLGTVARDPGLDTLLLDHETSKLGDTV------DHHSTISPTRLSPRRRSPTRSTSPVRLGRVTSTPA 2034
BLAST of Rootletin-2 vs. Ensembl Cavefish
Match: crocc2 (rootletin-like [Source:NCBI gene;Acc:103030367]) HSP 1 Score: 475.322 bits (1222), Expect = 2.688e-136 Identity = 471/1521 (30.97%), Postives = 847/1521 (55.69%), Query Frame = 1
Query: 1936 SPVSIA-----DSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKA---KESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEEL-KSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLE-ESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSD--LDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQ--ALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNK 6456
SPV D+T +V+ AL +R QDL + +++A + ++ +L DSE+E R LE++ +L+ E + +I R+ +R R ++ ++ +K +L+K + + + ++E+L++ + ++QR ++ L +DL+R L R+ E ER ++IE E+K S +++E+ +++E+L++ L+KEVLE E + L +L+K E AE E+ K ++EEA LRD F ++ ++ L K+ E ++ Q E+EK LS K+ E E+ REEL ++ E ++ K L S +++S L EL+ L EK + + ++ AL +L +R++E ++++Q++ +++E LA++K L QLT + + A + + E E L+ ++++ Q+ IS LEA + LE L++ + E R+Q E + Q++S+A +++L++KL ++E+ + L S +++ +E +E ++E +R +E+++ Q + E ++LR R D ++L +E+ Q+ D LL+AE KQ A++ E EK + E+I L + T+ + ER R + + +QD++T +L++ RL FE+ + K L +EL Q+++ +E E+L +S+L++ EE+RD +R++L E+ ++RE +RE RRE ++ +R +E E I SN+ELR +K +E + ++R L++ + +L++LEE K LQ+E R ++++ EK+ + RREL+ELR +VK L+ + G+ EV LQ R+ +E +E EAR+E+F LKQ+V+ES+A +E K++ R+ ELEE+ EK ++ D L+D + + E LE L+ E N L E R LE Q+ + D R E RL+ + S LR+ +G + R+ SPEKG S G G V S S + G D LD E+V+ ALR+ Q + +RERDD +A+ +LK + +Q Q + R QL+ + ++E+ K+ + RL + Q +L +QEE R +RER+ + +++ +L+ L + + LQER++++ E+ E R L + D AE R ++LEL R LEGELQR ++ + E E L++R+ +L +++ + E L++ +R + LAR E +E ++K+ +L E + + +++ QLQSTL +SE + R LQERLE ++ LS++K QN+ L +R++ Q+ E E R E++ L + L QR+++ +E ++ ++ L ER+ +L SL L+ +R ++K+ + K+K +LK+TL K+E+E+ R EE + ++ E ++ LE + H + L++QL+ EQ H+QR++E+T+R + E+ E +RL+ + E+ L+ RE++HRQ+V+ LEEQ+ LK+QL QE+++R+ +++
Sbjct: 472 SPVPTVSSPQRDNTLISVQRALSQRQKLTQDLQTCLDAALDQAAVLRDRLQDSESECRQLEQRIQQLQQENRHAEKAGVEISRDAQRYRTSLGLITSEKGELEKHLFVAQHQLNHDQAELERLRSSSLDVQRQRDILRQQREDLERQLARERSEAERGLRTIEQLEAKHSDVRKELVTVREALSQITLQKEVLEDEKASLEKALSKAEAQNAEQELALTKLQSEEAGLRDSFEKMAALCEGLAKDKVELNRVLLQVEAEKAELSERKREAELERAAAREELALIQQELMDVVAEKRALEASHVLLQESRAGLDTELTLLQREKSSVLEQLAQVSEQKQALMEQLSVCQRESELQTSSLQRTGREREELARDKAGLSVQLTAEQRRAKTLAQELAAARVEWESLESAVFDGQEQISALEADLSRLEGERGNLQQANEALTREVSRIQSELE---QQVSQALLERQALELKLTQAERNAQRSLASAQQSHQEQLEAERKDKESVRLALTAQREQVEEQLRVEYEELRLRSRTDLQQLQEELARAQQHCTDSLLQAESHKQQALSEKEAEKTVLTERILSLQRDIETTALETERMRRDFLNKQEQDKDTAAGLQSELQQLRLHFEESLSSREISEKRLNDQIRELSLQRHEAQQEVEQLRRSVLEV-EESRDGVRKELVEARAELRECVQEREAGRRESLELRRALGNESREKEAIHTSNQELRTSVKRAESENNGLKRTLEEREQRLTVLEECKSSLQQEALKVRNSMRELEKSHLQARRELQELRRKVKTLEGQCGQQEQEVGELQARLVQEEQREEEARKESFSLKQRVLESDAGREAALKEVAGLQRRVAELEEV-QRVEKECQRQRDASLQDSQRRQREETARLEGALQEVQAELREQNVELKLAEGRGRSLEEQLALADASRSDLEQRLSGLSSALRRTLGIGCRARSPTPRPRGRRPSPWRNRSPEKGSESVSG-------------GPMGSVQDPSVSPVHGEDGKLDVESVQAALRNFQQELRDAQRERDD--AQAQVMSLKRQLSELQAGQEKSSARAQQLKHSIKDLEQGKRDLAERLEAVQASLSLQEEAGRRGDRERRVMEEELSRLKNGLQASDAGARALQERLERVEQSEAGLGAECRRLKECWDAAEARASRLELSHRTLEGELQRSQIRSAELEAELSSLQERMSSLRRELGESEECTALLKVEGERAATALARAELQEAQLREKLQSTAAALKESCSSAGAAKEQTAQLQSTLTASELEGRTLQERLEKMREALSDSKKQNYALSERLQNLQRTQEEYELRVSELDKHTHSLQEALRQREQVVEEARADCTVLQKDRVELQERVTNLQTSLHSLQDDRTQLDKILTRLGKDKAALKRTLQKVEQERRRQEEEVLCVGRQKEELEQSLSSLEQQLSDTHAESHTLKSQLSHLEQAHSQRLLEVTARHRQELELETERLRGSQQQAERALEAREKAHRQRVRCLEEQVCTLKEQLEQEMRRRQTYMSQ 1972 HSP 2 Score: 94.3597 bits (233), Expect = 1.318e-18 Identity = 92/354 (25.99%), Postives = 163/354 (46.05%), Query Frame = 1
Query: 316 MPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTN 1377
+P ++ II R+ + P + L G+G + Q EN LKD L RL +RD L K A+ +L + A+ GD + +++L D+ R Y+ KL A D Q +QA+L+ +LQ K+ Q + R G ++ QQ + SE+ +L+ QT +D + + + +E + ++D +S + L+EE+ + L ++ ALLR+QL++A ANQ LTE + EE EQ+D+ + ++ + L EQ R+++LW + + F +++ +R+L +R + + L +AC NL +
Sbjct: 51 VPARIRQIITRNLAEG------------PAVSGAGV-----LGAVGSGGEQSVQ--EENRRLKDLLSQT-----RL--DRDQLLSKQTALTSRLEQMLAAQS-GDSDQDSVYGGE-------------QQRLRDESRAYRLKLQAYQDSQHRQAQLVHKLQTKVLQYKKRCG---EMEQQVLEKTSELEKLRLSLQT-------HLDSSAHRFQLSEQEHSLDAQSKLALLEEERRRCSGLTKVNALLREQLEQANEANQALTESLHEAQEEA-------EQRDIRLRREQEMSASRLGREQARVRALWRQAASLRSTFTQLRAFADRNLSDIRGEFANANRKLHVACLNLQSG 347
BLAST of Rootletin-2 vs. Ensembl Cavefish
Match: crocc2 (rootletin-like [Source:NCBI gene;Acc:103030367]) HSP 1 Score: 465.307 bits (1196), Expect = 3.790e-133 Identity = 460/1521 (30.24%), Postives = 823/1521 (54.11%), Query Frame = 1
Query: 1936 SPVSIA-----DSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKA---KESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEEL-KSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLE-ESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSD--LDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQ--ALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNK 6456
SPV D+T +V+ AL +R QDL + +++A + ++ +L DSE+E R LE++ +L+ E + +I R+ +R R ++ ++ +K +L+K + + + ++E+L++ + ++QR ++ L +DL+R L R+ E ER ++IE E+K S +++E+ +++E+L++ L+KEVLE E + L +L+K E AE E+ K ++EEA LRD F ++ ++ L K+ E ++ Q E+EK LS K+ E E+ REEL ++ E ++ K L S +++S L EL+ L EK + + ++ AL +L +R++E ++++Q++ +++E LA++K L QLT + + A + + E E L+ ++++ Q+ IS LEA + LE L++ + E R+Q E + Q++S+A +++L++KL ++E+ + L S +++ +E +E ++E +R +E+++ Q + E ++LR R D ++L +E+ Q+ D LL+AE KQ A++ E EK + E+I L + T+ + ER R + + +QD++T +L++ RL FE+ + K L +EL Q+++ +E E+L +S+L++ EE+RD +R++L E+ ++RE +RE RRE ++ +R +E E I SN+ELR +K +E + ++R L++ + +L++LEE K LQ+E R ++++ EK+ + RREL+ELR +VK L+ + G+ EV LQ R+ +E +E EAR+E+F LKQ+V+ES+A +E K++ R+ ELEE+ EK ++ D L+D + + E LE L+ E N L E R LE Q+ + D R E RL+ + S LR+ +G + R+ SPEKG S G G V S S + G D LD E+V+ ALR+ Q + +RERDD +A+ +LK + +Q Q + R QL+ + ++E+ K+ + RL + Q +L +QEE R +RER+ + +++ +L+ L + + LQER++++ E+ E R L + D AE R ++LEL R LEGELQR ++ + E E L++R+ +L +++ + E L++ +R + LAR E +E ++K+ +L E + + +++ QLQSTL +SE + R LQERLE ++ LS++K QN+ L +R++ Q+ E E R E++ L + L QR+++ +E ++ ++ L ER+ +L SL L+ +R ++ D+ RL + L R +QK +QL+ EQ H+QR++E+T+R + E+ E +RL+ + E+ L+ RE++HRQ+V+ LEEQ+ LK+QL QE+++R+ +++
Sbjct: 472 SPVPTVSSPQRDNTLISVQRALSQRQKLTQDLQTCLDAALDQAAVLRDRLQDSESECRQLEQRIQQLQQENRHAEKAGVEISRDAQRYRTSLGLITSEKGELEKHLFVAQHQLNHDQAELERLRSSSLDVQRQRDILRQQREDLERQLARERSEAERGLRTIEQLEAKHSDVRKELVTVREALSQITLQKEVLEDEKASLEKALSKAEAQNAEQELALTKLQSEEAGLRDSFEKMAALCEGLAKDKVELNRVLLQVEAEKAELSERKREAELERAAAREELALIQQELMDVVAEKRALEASHVLLQESRAGLDTELTLLQREKSSVLEQLAQVSEQKQALMEQLSVCQRESELQTSSLQRTGREREELARDKAGLSVQLTAEQRRAKTLAQELAAARVEWESLESAVFDGQEQISALEADLSRLEGERGNLQQANEALTREVSRIQSELE---QQVSQALLERQALELKLTQAERNAQRSLASAQQSHQEQLEAERKDKESVRLALTAQREQVEEQLRVEYEELRLRSRTDLQQLQEELARAQQHCTDSLLQAESHKQQALSEKEAEKTVLTERILSLQRDIETTALETERMRRDFLNKQEQDKDTAAGLQSELQQLRLHFEESLSSREISEKRLNDQIRELSLQRHEAQQEVEQLRRSVLEV-EESRDGVRKELVEARAELRECVQEREAGRRESLELRRALGNESREKEAIHTSNQELRTSVKRAESENNGLKRTLEEREQRLTVLEECKSSLQQEALKVRNSMRELEKSHLQARRELQELRRKVKTLEGQCGQQEQEVGELQARLVQEEQREEEARKESFSLKQRVLESDAGREAALKEVAGLQRRVAELEEV-QRVEKECQRQRDASLQDSQRRQREETARLEGALQEVQAELREQNVELKLAEGRGRSLEEQLALADASRSDLEQRLSGLSSALRRTLGIGCRARSPTPRPRGRRPSPWRNRSPEKGSESVSG-------------GPMGSVQDPSVSPVHGEDGKLDVESVQAALRNFQQELRDAQRERDD--AQAQVMSLKRQLSELQAGQEKSSARAQQLKHSIKDLEQGKRDLAERLEAVQASLSLQEEAGRRGDRERRVMEEELSRLKNGLQASDAGARALQERLERVEQSEAGLGAECRRLKECWDAAEARASRLELSHRTLEGELQRSQIRSAELEAELSSLQERMSSLRRELGESEECTALLKVEGERAATALARAELQEAQLREKLQSTAAALKESCSSAGAAKEQTAQLQSTLTASELEGRTLQERLEKMREALSDSKKQNYALSERLQNLQRTQEEYELRVSELDKHTHSLQEALRQREQVVEEARADCTVLQKDRVELQERVTNLQTSLHSLQDDR------------------------------------------TQLDKILTRLGKDKAALKRTLQK--SQLSHLEQAHSQRLLEVTARHRQELELETERLRGSQQQAERALEAREKAHRQRVRCLEEQVCTLKEQLEQEMRRRQTYMSQ 1928 HSP 2 Score: 93.9745 bits (232), Expect = 1.774e-18 Identity = 92/354 (25.99%), Postives = 163/354 (46.05%), Query Frame = 1
Query: 316 MPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTN 1377
+P ++ II R+ + P + L G+G + Q EN LKD L RL +RD L K A+ +L + A+ GD + +++L D+ R Y+ KL A D Q +QA+L+ +LQ K+ Q + R G ++ QQ + SE+ +L+ QT +D + + + +E + ++D +S + L+EE+ + L ++ ALLR+QL++A ANQ LTE + EE EQ+D+ + ++ + L EQ R+++LW + + F +++ +R+L +R + + L +AC NL +
Sbjct: 51 VPARIRQIITRNLAEG------------PAVSGAGV-----LGAVGSGGEQSVQ--EENRRLKDLLSQT-----RL--DRDQLLSKQTALTSRLEQMLAAQS-GDSDQDSVYGGE-------------QQRLRDESRAYRLKLQAYQDSQHRQAQLVHKLQTKVLQYKKRCG---EMEQQVLEKTSELEKLRLSLQT-------HLDSSAHRFQLSEQEHSLDAQSKLALLEEERRRCSGLTKVNALLREQLEQANEANQALTESLHEAQEEA-------EQRDIRLRREQEMSASRLGREQARVRALWRQAASLRSTFTQLRAFADRNLSDIRGEFANANRKLHVACLNLQSG 347
BLAST of Rootletin-2 vs. Ensembl Cavefish
Match: si:dkey-230p4.1 (trichohyalin-like [Source:NCBI gene;Acc:103036019]) HSP 1 Score: 78.1814 bits (191), Expect = 1.291e-13 Identity = 39/121 (32.23%), Postives = 76/121 (62.81%), Query Frame = 1
Query: 985 LESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSL 1347
LES + L+EEQ +S++L+++ ALLR QL ++ ANQ L +D+++L+ + S E Q+++DW+ ++ + E+ R+ LW V+ +RQ + +K++ ++DL +LR + + +L
Sbjct: 128 LESTLIRLEEEQQRSVALVEVNALLRSQLSQSAEANQTLQDDLRKLTADWSRAVEEAGQREIDWQKEKEVLVGCVSAERARLMMLWGKAVSLRRQCHTVKTATDKDLWELRAEFSRLSSTL 248
BLAST of Rootletin-2 vs. Ensembl Cavefish
Match: si:dkey-230p4.1 (trichohyalin-like [Source:NCBI gene;Acc:103036019]) HSP 1 Score: 78.1814 bits (191), Expect = 1.291e-13 Identity = 39/121 (32.23%), Postives = 76/121 (62.81%), Query Frame = 1
Query: 985 LESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSL 1347
LES + L+EEQ +S++L+++ ALLR QL ++ ANQ L +D+++L+ + S E Q+++DW+ ++ + E+ R+ LW V+ +RQ + +K++ ++DL +LR + + +L
Sbjct: 128 LESTLIRLEEEQQRSVALVEVNALLRSQLSQSAEANQTLQDDLRKLTADWSRAVEEAGQREIDWQKEKEVLVGCVSAERARLMMLWGKAVSLRRQCHTVKTATDKDLWELRAEFSRLSSTL 248
BLAST of Rootletin-2 vs. Ensembl Cavefish
Match: ENSAMXT00000053516.1 (pep primary_assembly:Astyanax_mexicanus-2.0:22:18273005:18276973:-1 gene:ENSAMXG00000035105.1 transcript:ENSAMXT00000053516.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 62.3882 bits (150), Expect = 2.070e-10 Identity = 49/168 (29.17%), Postives = 89/168 (52.98%), Query Frame = 1
Query: 685 QTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDE 1188
Q + LR++L+++ YKRKL A + Q +QA+L+++LQ K+ Q ++ L Q K H S R + E +++ + V S+S SL + A+LR+QL++A+ AN+ L++D++RL+ + + + ELEQ++ DW+ +E
Sbjct: 22 QNVDLRRRLEEEQAAYKRKLTAYQEGQQRQAQLVQKLQAKVFQ-----TFIKHLQHQ-----------KPH-----SHQQRNCSLYET--------QSVCVCVCV-------SRSSSLSAVNAMLREQLEQASLANEALSQDIRRLTADWTKAREELEQREADWRREE 153
BLAST of Rootletin-2 vs. Ensembl Nematostella
Match: EDO42343 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1K9]) HSP 1 Score: 321.242 bits (822), Expect = 2.376e-95 Identity = 241/604 (39.90%), Postives = 392/604 (64.90%), Query Frame = 1
Query: 4924 GSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKN--SALKS-DETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEI-----RRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPT 6711
++DPE VR+ALRD Q + ERERD+ +A N AL +E ++DQ +Q I QK+ GE EE+++G D RLSSAQTALM+QEETI R ERERK+L +K+ L+ LA E +++ L+++V ++ ES ++E+ + +++ E+R T++EL +R +EG+++RL+M ++ E E L++R+D + K +LES+A SLQLT+DRL++ LA+TEEEE K+KV +L++SL++ QS+Q+++ QLQ L +SEHDR+++QERLE++K+ EAK +N+ L DRM+ + E +++ R+ E+EG+I++L QIL Q++E E+EL ++I + EK L ERL S+A E E+R++E+ H++ EK+K +L+ TLDK+E+EK ++E+ + R D + E EN+ LHRQ+Q LQ QLAE EQ HA++++E+TSR + E+ E DR + + EKT RER+H+Q+VK LEEQ+ LKDQL++EL+K++ L ++ + ++I D++S LE + N +++ + +YEP + +++++ L + Y S RP S S ++++P
Sbjct: 2 SGEIDPETVRVALRDFAQSMKEAERERDEAVTRANNLQRALAELEEERTRMDQRMQSI---QKSLGESEEERRGADGRLSSAQTALMLQEETIRRLERERKALNEKITALDSSLAQAEGDRRQLRDKVANLQQSESKSDQEKEAMRAQIENTESRLTKVELKKRSVEGDIERLRMLNSENEAEKIALQERIDQMLKSQQELESRATSLQLTVDRLTLALAKTEEEEMAFKNKVTELSMSLNDSNSTSQSLQERIQQLQRALTNSEHDRKIMQERLEALKNAQQEAKGRNNMLQDRMQQMKNEQADADVRRMELEGQIRQLQQILRQQKEAEEELVARIGKLQEEKRELQERLAKFQRSVAAAEQEKRELERAHVRLEKDKKALRNTLDKIEREKLETDETNTRLRDDRERLDRSSANFEHENQELHRQIQILQQQLAETEQSHARKLVEVTSRHRQEIEMEGDRARQSQGQLEKTQMARERAHKQRVKGLEEQVATLKDQLAKELQKKQSYLTRTAQK-SDEIKDLRSKLEDSLNIVAR----DTIYEPTVLDRESQKLEESLVDGSYG-----------SIRPKSASPPPRYSADKFATSTPA 586
BLAST of Rootletin-2 vs. Ensembl Medaka
Match: CROCC (ciliary rootlet coiled-coil, rootletin [Source:NCBI gene;Acc:101159974]) HSP 1 Score: 400.208 bits (1027), Expect = 3.511e-113 Identity = 417/1308 (31.88%), Postives = 699/1308 (53.44%), Query Frame = 1
Query: 2557 EYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLE--TANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFD-EKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMREN---EELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGS--DLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQI--LSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNL 6450
E + +K + E+A LRD ++ ++N LV++ + I Q E EK L +K+ EQEK IR+EL+R E + EL + L QS+Q+ E S ++ EL L E+ +L+ A V +L +EL A+ + +R A++++ + + L K+K L+ QLT E E A+ + + E+E L+ SL+++QQ + Q E+ E LE+ Q L + D E Q Q E D Q L++A + Q+ E + ++R + M+++ ++ + ++E++D + R+KEEL + +Q ERD LL+AE KQ A++L E EK + EK+S L L + ERT E +Q+Q + +L++ R Q E H+R+I +L N+ D+R E+ ++ L AEE R+ LR+D E+ ++ +T++ E RRE + +R+ +V +E + + SN +LRE L+++E ++I ++RQ ++ + +L +LEE QKEV + R L++ E++R++ RREL+ELR Q+K LD +R + E++ LQ R++ +E +E E +E F LKQK+ E++ T K+L +S E S E+ E K L++ NL + + + L +T E ++ + ++ E RL+++ S L + +G GR S S + D +G + + +P + +LDP+ +R LRD Q + R+RDD + + + +E ++ + A R QLQ + E +E K+G+D RL+S Q L QE+ + R +RER++L D+V +LER L E EKK+ QE+++K R E+ E ER+ L +A++ AE R T++EL RR LEGELQRLK+G D+E E+Q ++R D L +Q+++ E++ LQ +DRLS L + +E E K KV L+ SL E + S Q +L LQ TL+ E D+R+LQE+++ + +++EAK L +R+++ Q EL +SE + E+E E+K ++ L QR E Q I ++ E+ + ERL +L ++A LE+E++D E+ + EK+K++L+ TLDK+E++K + EE + +++ D +E E + +Q+ LQ LAE EQ H+ E R ++E E ++L+++ E+TL RER+HR +VK LEEQ++ LK+QL QE+K+R+ L
Sbjct: 431 ELSLHLSKLQYEDAALRDSLTKMGNLNEGLVQDKVDLNKYILQLEEEKAVLQAQKREAEQEKLSIRDELVRQEQNRLELESSRVTLQQSLQDTEFSRVGVEAELQNLRAERLKLQEKVAQVA------SLDSELSLAKGEGQRSEMALEEAGRSRAELTKDKAALVVQLTASERENAMLAEELTAFRSERETLETSLFDAQQQLLQAESCREQLEAENQNLRVRCETATDAENQLAQAERDK--QALTQALSAAQL-----EAQQASLVR--------------------HSLQMEHETAVR-KLRQEVEDQLQKARREKEELQDGLRALQHERDQSLLQAETEKQQALSLKEAEKTVLLEKVSGLQADLSALSLEAERTAREAAQYKEQEQIRVGALTSELQELRSQMEDAAAGHERDILSL--------NETCADLRSRADLEQCRASLSAAEENREQLRRDFLETERRLTQTQEASENHRREGAELRRSLCDVTRERDALSQSNAQLREALRSAETERISVKRQCEEKEQRLVVLEESLSSSQKEVAELRSCLREVERSRLEARRELQELRRQLKVLDADREQKGRELAELQTRLSLEEQREEERGKEVFILKQKLAETQ-TLSMTQKRLVES-------ESGWRSCERELTAQLQEARGCEKKLQDEAKNLSVRAQAAQESAGRLTAT-----------EAELTRAEASKRDLEFRLSSLQSALTRTLGI-----------------------GASGRASRGRSPGGRSTPDNT-MGSGAVSPEGGGTPLPPAQPELDPDTLRSGLRDFLQELRDAHRQRDDAQCQLMTLQRELEEQKLERECAENRSTQLQNSLKECQEGKRGLDDRLTSTQILLQQQEDAVKRVDRERRALADRVRELERSLHTAEMEKKHTQEQLNKQRATEARLEAERKRLREALEAAEARATRVELGRRSLEGELQRLKLGLGDREAESQASQERHDCLLRQVAEGEAQVSLLQTEVDRLSQALLKAQEGEAALKQKVTTLSQSLQEAAADHSSTQTRLTALQKTLSLVEQDKRLLQEKMDEARTSVTEAKRSMFALTERVQSLQGELTQSELLREELEAELKNTQEVRALRQRSGSLAETQHSIQKAQTERAAVEERLLALQRAVALLETEKKDAERQAARLEKDKDALRNTLDKVERQKLKCEEGSMRLSAEKTRLDRSLNAVEQELQEAQQQMLMLQVTLAEMEQAHSG--CEGLLRQRDEAQQEAEKLRNSCKDLERTLSTRERAHRHRVKGLEEQVSTLKEQLQQEMKRRQPPL 1651 HSP 2 Score: 127.487 bits (319), Expect = 1.045e-28 Identity = 103/361 (28.53%), Postives = 178/361 (49.31%), Query Frame = 1
Query: 292 SNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDT 1374
S D P +P V++I+ ++ D SS + S+ L+ EN L+ L +E+ L + +RD LAIK+ AI+E+L + +E + + SLA Q ++LR++LD++ Y+RKL A + Q +QA+L+++LQ K+ Q + R G +E+ Q+ S SE+ + +D + LE + L+EEQ +S SL + A+LR+QL++A AN+ L+ D++RL+ + + + ELEQK+ DW+ +E +F + E R+ + W VV F+R ++KSS D+ ++ + S Q R S +D+
Sbjct: 25 SPDDPPACLPARVREIVTKNLSD-----------------------SSECSPQAGEMSSLMSLQEENRVLQGELARLEDLLAHSRADRDELAIKYGAISERLEQALRSE------TGEGEADSQASRSLAQQNVELRRRLDEEQAAYRRKLTAYQEGQQRQAQLVQKLQAKVLQYKKRCGDLEQKLQEKS---SELEKC--------------------------SDSSSSLEEALLHLEEEQQRSSSLSAVNAMLREQLEQAGLANEALSRDIRRLTADWTKAREELEQKESDWRREEESFHSYFSSEHGRLLTFWRQVVGFRRHVCEMKSS---DVRGRLLSAQSSAQKFRKQLSEIDS 324
BLAST of Rootletin-2 vs. Ensembl Medaka
Match: CROCC (ciliary rootlet coiled-coil, rootletin [Source:NCBI gene;Acc:101159974]) HSP 1 Score: 384.8 bits (987), Expect = 4.254e-108 Identity = 407/1308 (31.12%), Postives = 696/1308 (53.21%), Query Frame = 1
Query: 2557 EYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLE--TANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEK------QRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQI--LSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNL 6450
E + +K + E+A LRD ++ ++N LV++ + I Q E EK L +K+ EQEK IR+EL+R E + EL + L QS+Q+ E S ++ EL L E+ +L+ A V +L +EL A+ + +R A++++ + + L K+K L+ QLT E E A+ + + E+E L+ SL+++QQ + Q E+ E LE+ Q L + E Q Q E D Q L++A + Q+ E + ++R + M+++ ++ + ++E++D + R+KEEL + +Q ERD LL+AE KQ A++L E EK + EK+S L L + ERT E +Q+Q + +L++ R Q E H+R+I +L +L ++ ++E E+ ++ L AEE R+ LR+D E+ ++ +T++ E RRE + +R+ +V +E + + SN +LRE L+++E ++I ++RQ ++ + +L +LEE QKEV + R L++ E++R++ RREL+ELR Q+K LD +R + E++ LQ R++ +E +E E +E F LKQK+ E++ T K+L +S E S E+ E K L++ NL + + + + + LS + R++ E ++ + ++ E RL+++ S L + +G GR S S + + G +++ + +LDP+ +R LRD Q + R+RDD + + + +E ++ + A R QLQ + E +E K+G+D RL+S Q L QE+ + R +RER++L D+V +LER L E EKK+ QE+++K R E+ E ER+ L +A++ AE R T++EL RR LEGELQRLK+G D+E E+Q ++R D L +Q+++ E++ LQ +DRLS L + +E E K KV L+ SL E + S Q +L LQ TL+ E D+R+LQE+++ + +++EAK L +R+++ Q EL +SE + E+E E+K ++ L QR E Q I ++ E+ + ERL +L ++A LE+E++D E+ + EK+K++L+ TLDK+E++K + EE + +++ D +E E + +Q+ LQ A H+ ++ R ++E E ++L+++ E+TL RER+HR +VK LEEQ+ QL QE+K+R+ L
Sbjct: 438 ELSLHLSKLQYEDAALRDSLTKMGNLNEGLVQDKVDLNKYILQLEEEKAVLQAQKREAEQEKLSIRDELVRQEQNRLELESSRVTLQQSLQDTEFSRVGVEAELQNLRAERLKLQEKVAQVA------SLDSELSLAKGEGQRSEMALEEAGRSRAELTKDKAALVVQLTASERENAMLAEELTAFRSERETLETSLFDAQQQLLQAESCREQLEAENQNLRVRCETATGEGKTNAENQLAQAERDK--QALTQALSAAQL-----EAQQASLVR--------------------HSLQMEHETAVR-KLRQEVEDQLQKARREKEELQDGLRALQHERDQSLLQAETEKQQALSLKEAEKTVLLEKVSGLQADLSALSLEAERTAREAAQYKEQEQIRVGALTSELQELRSQMEDAAAGHERDILSLNETCADLRSRADVALKELEQCRASLSAAEENREQLRRDFLETERRLTQTQEASENHRREGAELRRSLCDVTRERDALSQSNAQLREALRSAETERISVKRQCEEKEQRLVVLEESLSSSQKEVAELRSCLREVERSRLEARRELQELRRQLKVLDADREQKGRELAELQTRLSLEEQREEERGKEVFILKQKLAETQ-TLSMTQKRLVES-------ESGWRSCERELTAQLQEARGCEKKLQDEAKNLSVRAQAAQESAAQCSLQLSEAQGRLTATEAELTRAEASKRDLEFRLSSLQSALTRTLGI-----------------------GASGRASRGRSPGGSSASP-------GSISRGTPLPPAQPELDPDTLRSGLRDFLQELRDAHRQRDDAQCQLMTLQRELEEQKLERECAENRSTQLQNSLKECQEGKRGLDDRLTSTQILLQQQEDAVKRVDRERRALADRVRELERSLHTAEMEKKHTQEQLNKQRATEARLEAERKRLREALEAAEARATRVELGRRSLEGELQRLKLGLGDREAESQASQERHDCLLRQVAEGEAQVSLLQTEVDRLSQALLKAQEGEAALKQKVTTLSQSLQEAAADHSSTQTRLTALQKTLSLVEQDKRLLQEKMDEARTSVTEAKRSMFALTERVQSLQGELTQSELLREELEAELKNTQEVRALRQRSGSLAETQHSIQKAQTERAAVEERLLALQRAVALLETEKKDAERQAARLEKDKDALRNTLDKVERQKLKCEEGSMRLSAEKTRLDRSLNAVEQELQEAQQQMLMLQV-TASNSSAHSTGLL----RQRDEAQQEAEKLRNSCKDLERTLSTRERAHRHRVKGLEEQVWFHDSQLQQEMKRRQPPL 1668 HSP 2 Score: 126.331 bits (316), Expect = 2.611e-28 Identity = 97/334 (29.04%), Postives = 167/334 (50.00%), Query Frame = 1
Query: 292 SNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSN 1293
S D P +P V++I+ ++ D SS + S+ L+ EN L+ L +E+ L + +RD LAIK+ AI+E+L + +E + + SLA Q ++LR++LD++ Y+RKL A + Q +QA+L+++LQ K+ Q + R G +E+ Q+ S SE+ + +D + LE + L+EEQ +S SL + A+LR+QL++A AN+ L+ D++RL+ + + + ELEQK+ DW+ +E +F + E R+ + W VV F+R ++KSS+
Sbjct: 35 SPDDPPACLPARVREIVTKNLSD-----------------------SSECSPQAGEMSSLMSLQEENRVLQGELARLEDLLAHSRADRDELAIKYGAISERLEQALRSE------TGEGEADSQASRSLAQQNVELRRRLDEEQAAYRRKLTAYQEGQQRQAQLVQKLQAKVLQYKKRCGDLEQKLQEKS---SELEKC--------------------------SDSSSSLEEALLHLEEEQQRSSSLSAVNAMLREQLEQAGLANEALSRDIRRLTADWTKAREELEQKESDWRREEESFHSYFSSEHGRLLTFWRQVVGFRRHVCEMKSSS 310
BLAST of Rootletin-2 vs. Ensembl Medaka
Match: CROCC (ciliary rootlet coiled-coil, rootletin [Source:NCBI gene;Acc:101159974]) HSP 1 Score: 361.688 bits (927), Expect = 3.464e-101 Identity = 372/1185 (31.39%), Postives = 641/1185 (54.09%), Query Frame = 1
Query: 2935 ALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEK------QRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMREN---EELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGS--DLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQI--LSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNL 6450
+L +EL A+ + +R A++++ + + L K+K L+ QLT E E A+ + + E+E L+ SL+++QQ + Q E+ E LE+ Q L + E Q Q E D Q L++A + Q+ E + ++R + M+++ ++ + ++E++D + R+KEEL + +Q ERD LL+AE KQ A++L E EK + EK+S L L + ERT E +Q+Q + +L++ R Q E H+R+I +L N+ D+R E+ ++ L AEE R+ LR+D E+ ++ +T++ E RRE + +R+ +V +E + + SN +LRE L+++E ++I ++RQ ++ + +L +LEE QKEV + R L++ E++R++ RREL+ELR Q+K LD +R + E++ LQ R++ +E +E E +E F LKQK+ E++ +E L ++L + ++ E E S E+ E K L++ NL + + + + + LS + R++ E ++ + ++ E RL+++ S L + +G + + R + N++ G + + +P + +LDP+ +R LRD Q + R+RDD + + + +E ++ + A R QLQ + E +E K+G+D RL+S Q L QE+ + R +RER++L D+V +LER L E EKK+ QE+++K R E+ E ER+ L +A++ AE R T++EL RR LEGELQRLK+G D+E E+Q ++R D L +Q+++ E++ LQ +DRLS L + +E E K KV L+ SL E + S Q +L LQ TL+ E D+R+LQE+++ + +++EAK L +R+++ Q EL +SE + E+E E+K ++ L QR E Q I ++ E+ + ERL +L ++A LE+E++D E+ + EK+K++L+ TLDK+E++K + EE + +++ D +E E + +Q+ LQ LAE EQ H+ E R ++E E ++L+++ E+TL RER+HR +VK LEEQ++ LK+QL QE+K+R+ L
Sbjct: 416 SLDSELSLAKGEGQRSEMALEEAGRSRAELTKDKAALVVQLTASERENAMLAEELTAFRSERETLETSLFDAQQQLLQAESCREQLEAENQNLRVRCETATGEGKTNAENQLAQAERDK--QALTQALSAAQL-----EAQQASLVR--------------------HSLQMEHETAVR-KLRQEVEDQLQKARREKEELQDGLRALQHERDQSLLQAETEKQQALSLKEAEKTVLLEKVSGLQADLSALSLEAERTAREAAQYKEQEQIRVGALTSELQELRSQMEDAAAGHERDILSL--------NETCADLRSRADLEQCRASLSAAEENREQLRRDFLETERRLTQTQEASENHRREGAELRRSLCDVTRERDALSQSNAQLREALRSAETERISVKRQCEEKEQRLVVLEESLSSSQKEVAELRSCLREVERSRLEARRELQELRRQLKVLDADREQKGRELAELQTRLSLEEQREEERGKEVFILKQKLAETQTARESLKRELSMTQKRLVESESGWRSCERELTAQLQEARGCEKKLQDEAKNLSVRAQAAQESAAQCSLQLSEAQGRLTATEAELTRAEASKRDLEFRLSSLQSALTRTLGI---------------------GASGRARSTPDNTM-----------GSGAVSPEGGGTPLPPAQPELDPDTLRSGLRDFLQELRDAHRQRDDAQCQLMTLQRELEEQKLERECAENRSTQLQNSLKECQEGKRGLDDRLTSTQILLQQQEDAVKRVDRERRALADRVRELERSLHTAEMEKKHTQEQLNKQRATEARLEAERKRLREALEAAEARATRVELGRRSLEGELQRLKLGLGDREAESQASQERHDCLLRQVAEGEAQVSLLQTEVDRLSQALLKAQEGEAALKQKVTTLSQSLQEAAADHSSTQTRLTALQKTLSLVEQDKRLLQEKMDEARTSVTEAKRSMFALTERVQSLQGELTQSELLREELEAELKNTQEVRALRQRSGSLAETQHSIQKAQTERAAVEERLLALQRAVALLETEKKDAERQAARLEKDKDALRNTLDKVERQKLKCEEGSMRLSAEKTRLDRSLNAVEQELQEAQQQMLMLQVTLAEMEQAHSG--CEGLLRQRDEAQQEAEKLRNSCKDLERTLSTRERAHRHRVKGLEEQVSTLKEQLQQEMKRRQPPL 1530 HSP 2 Score: 95.9005 bits (237), Expect = 4.796e-19 Identity = 58/177 (32.77%), Postives = 107/177 (60.45%), Query Frame = 1
Query: 844 LNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDT 1374
L ++N L+ E++RL++ + +D R ++A + +E D + LE + L+EEQ +S SL + A+LR+QL++A AN+ L+ D++RL+ + + + ELEQK+ DW+ +E +F + E R+ + W VV F+R ++KSS ERDL +R + + + ++++C+ L
Sbjct: 7 LQEENRVLQGELARLEDLLAHSRAD---RDELAIKYGAISERDSSSSLEEALLHLEEEQQRSSSLSAVNAMLREQLEQAGLANEALSRDIRRLTADWTKAREELEQKESDWRREEESFHSYFSSEHGRLLTFWRQVVGFRRHVCEMKSSAERDLSDMRGELVRMSHLVQVSCAGLSA 180
BLAST of Rootletin-2 vs. Ensembl Medaka
Match: CROCC (ciliary rootlet coiled-coil, rootletin [Source:NCBI gene;Acc:101159974]) HSP 1 Score: 348.206 bits (892), Expect = 1.482e-96 Identity = 401/1309 (30.63%), Postives = 690/1309 (52.71%), Query Frame = 1
Query: 2665 FKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQ--DELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQK------------------SMKDK--------EVLAKEKIDL-------ISQLTTFEHELREN---ADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMREN---EELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGS--DLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLA-EAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKS 6459
F+ + + +S K +AL+++K E + EKE+L Q +D N+EK+ + L +++ +++YEK QL A+ QRER+ E A D ER +Q+ +++D E L ++K+DL ++ F L+ A A + E+E L+ SL+++QQ + Q E+ E LE+ Q L + E +RL+ + + +L + + K++L L+ ++ E + R +E++ERL E+E +R+ E + ++E++D + R+KEEL + +Q ERD LL+AE KQ A++L E EK + EK+S L L + ERT E +Q+Q + +L++ R Q E H+R+I +L N+ D+R E+ ++ L AEE R+ LR+D E+ ++ +T++ E RRE + +R+ +V +E + + SN +LRE L+++E ++I ++RQ ++ + +L +LEE QKEV + R L++ E++R++ RREL+ELR Q+K LD +R + E++ LQ R++ +E +E E +E F LKQK+ E++ +E L ++L + ++ E E S E+ E K L++ NL + + + + + LS + R++ E ++ + ++ E RL+++ S L + +G + + R + N++ G + + +P + +LDP+ +R LRD Q + R+R + K + + +E ++ + A R QLQ + E +E K+G+D RL+S Q L QE+ + R +RER++L D+V +LER L E EKK+ QE+++K R E+ E ER+ L +A++ AE R T++EL RR LEGELQRLK+G D+E E+Q ++R D L +Q+++ E++ LQ +DRLS L + +E E K KV L+ SL E + S Q +L LQ TL+ E D+R+LQE+++ + +++EAK L +R+++ Q EL +SE + E+E E+K + L QR E Q I ++ E+ + ERL +L ++A LE+E++D E+ + EK+K++L+ TLDK+E++K + EE S+ +E R L N V + Q L + Q H+ E R ++E E ++L+++ E+TL RER+HR +VK LEEQ++ LK+QL QE+K+R+ L +
Sbjct: 394 FRKQLSEIDSAKRDADQRNQALQRDKDAALRERETAQREKEQLKQERDN---EKANLEKAVQALHSSNQMLQMDYEKLQLAVASA--QRERDREREEKEAAIHDGERWKTEIQRITNKELSLHLSKLQYEDAALRDSLTKMGNLNEGLVQDKVDLNKYILQVMAMCLHFSLVLKYRILVAFACLACRSERETLETSLFDAQQQLLQAESCREQLEAENQNLRVRCETATVELRRLRSDAENQLAQAERDKQALTQALSAAQLEAQQASRKATSEHQEEVERLALEKEVVRHSLQMEHETAVRKLRQEVEDQLQKARREKEELQDGLRALQHERDQSLLQAETEKQQALSLKEAEKTVLLEKVSGLQADLSALSLEAERTAREAAQYKEQEQIRVGALTSELQELRSQMEDAAAGHERDILSL--------NETCADLRSRADLEQCRASLSAAEENREQLRRDFLETERRLTQTQEASENHRREGAELRRSLCDVTRERDALSQSNAQLREALRSAETERISVKRQCEEKEQRLVVLEESLSSSQKEVAELRSCLREVERSRLEARRELQELRRQLKVLDADREQKGRELAELQTRLSLEEQREEERGKEVFILKQKLAETQTARESLKRELSMTQKRLVESESGWRSCERELTAQLQEARGCEKKLQDEAKNLSVRAQAAQESAAQCSLQLSEAQGRLTATEAELTRAEASKRDLEFRLSSLQSALTRTLGI---------------------GASGRARSTPDNTM-----------GSGAVSPEGGGTPLPPAQPELDPDTLRSGLRDFLQELRDAHRQRVNDCFKHETDTAQLEEQKLERECAENRSTQLQNSLKECQEGKRGLDDRLTSTQILLQQQEDAVKRVDRERRALADRVRELERSLHTAEMEKKHTQEQLNKQRATEARLEAERKRLREALEAAEARATRVELGRRSLEGELQRLKLGLGDREAESQASQERHDCLLRQVAEGEAQVSLLQTEVDRLSQALLKAQEGEAALKQKVTTLSQSLQEAAADHSSTQTRLTALQKTLSLVEQDKRLLQEKMDEARTSVTEAKRSMFALTERVQSLQGELTQSELLREELEAELKNTQEALRQRSGSLAETQHSIQKAQTERAAVEERLLALQRAVALLETEKKDAERQAARLEKDKDALRNTLDKVERQKLKCEEG---SMRLSAEKTRLDRSL---NAVEQELQEAQQQMLMLQVTQAHSG--CEGLLRQRDEAQQEAEKLRNSCKDLERTLSTRERAHRHRVKGLEEQVSTLKEQLQQEMKRRQPPLPST 1649 HSP 2 Score: 145.206 bits (365), Expect = 4.751e-34 Identity = 103/361 (28.53%), Postives = 179/361 (49.58%), Query Frame = 1
Query: 292 SNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDT 1374
S D P +P V++I+ ++ D SS + S+ L+ EN L+ L +E+ L + +RD LAIK+ AI+E+L + +E + + SLA Q ++LR++LD++ Y+RKL A + Q +QA+L+++LQ K+ Q + R G +E+ Q+ KS+E +K S + L+EEQ +S SL + A+LR+QL++A AN+ L+ D++RL+ + + + ELEQK+ DW+ +E +F + E R+ + W VV F+R ++KSS ERDL +R + + + ++++C+ L
Sbjct: 25 SPDDPPACLPARVREIVTKNLSD-----------------------SSECSPQAGEMSSLMSLQEENRVLQGELARLEDLLAHSRADRDELAIKYGAISERLEQALRSE------TGEGEADSQASRSLAQQNVELRRRLDEEQAAYRRKLTAYQEGQQRQAQLVQKLQAKVLQYKKRCGDLEQKLQE---------------------------------KSSELEKC----SALLHLEEEQQRSSSLSAVNAMLREQLEQAGLANEALSRDIRRLTADWTKAREELEQKESDWRREEESFHSYFSSEHGRLLTFWRQVVGFRRHVCEMKSSAERDLSDMRGELVRMSHLVQVSCAGLSA 319
BLAST of Rootletin-2 vs. Ensembl Medaka
Match: CROCC (ciliary rootlet coiled-coil, rootletin [Source:NCBI gene;Acc:101159974]) HSP 1 Score: 347.436 bits (890), Expect = 2.315e-96 Identity = 392/1308 (29.97%), Postives = 674/1308 (51.53%), Query Frame = 1
Query: 2557 EYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLE--TANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEK------QRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGS--DLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNL 6450
E + +K + E+A LRD ++ ++N LV++ + I Q E EK L +K+ EQEK IR+EL+R E + EL + L QS+Q+ E S ++ EL L E+ +L+ A V +L +EL A+ + +R A++++ + + L K+K L+ QLT E E A+ + + E+E L+ SL+++QQ + Q E+ E LE+ Q L + E Q Q E D Q L++A + Q+ E + ++R + M+++ ++ + ++E++D + R+KEEL + +Q ERD LL+AE KQ A++L E EK + EK+S L L + ERT E +Q+Q + +L++ R Q E H+R+I +L +L ++ ++E E+ ++ L AEE R+ LR+D E+ ++ +T++ E RRE + +R+ +V +E + + SN +LRE L+++E ++I ++RQ ++ + +L +LEE QKEV + R L++ E++R++ RREL+ELR Q+K LD +R + E++ LQ R++ +E +E E +E F LKQK+ E++ T K+L +S E S E+ E K L++ NL + + + + + LS + R++ E ++ + ++ E RL+++ S L + +G + + S N +G + + +P + +LDP+ +R LRD Q + R+RDD + + + +E ++ + A R QLQ + E +E K+G+D RL+S Q L QE+ + R +RER++L D+V +LER L E EKK+ QE+++K R E+ E ER+ L +A++ AE R T++EL RR LEGELQRLK+G D+E E+Q ++R D L +Q+++ E++ LQ +DRLS L + +E E K KV L+ SL E A+++H Q RL +++ LS L+E + R ++ G + + L+ E Q I ++ E+ + ERL +L ++A LE+E++D E+ + EK+K++L+ TLDK+E++K + EE + +++ D +E E + +Q+ LQ + EQ H+ E R ++E E ++L+++ E+TL RER+HR +VK LEEQ++ LK+QL QE+K+R+ L
Sbjct: 452 ELSLHLSKLQYEDAALRDSLTKMGNLNEGLVQDKVDLNKYILQLEEEKAVLQAQKREAEQEKLSIRDELVRQEQNRLELESSRVTLQQSLQDTEFSRVGVEAELQNLRAERLKLQEKVAQVA------SLDSELSLAKGEGQRSEMALEEAGRSRAELTKDKAALVVQLTASERENAMLAEELTAFRSERETLETSLFDAQQQLLQAESCREQLEAENQNLRVRCETATGEGKTNAENQLAQAERDK--QALTQALSAAQL-----EAQQASLVR--------------------HSLQMEHETAVR-KLRQEVEDQLQKARREKEELQDGLRALQHERDQSLLQAETEKQQALSLKEAEKTVLLEKVSGLQADLSALSLEAERTAREAAQYKEQEQIRVGALTSELQELRSQMEDAAAGHERDILSLNETCADLRSRADVALKELEQCRASLSAAEENREQLRRDFLETERRLTQTQEASENHRREGAELRRSLCDVTRERDALSQSNAQLREALRSAETERISVKRQCEEKEQRLVVLEESLSSSQKEVAELRSCLREVERSRLEARRELQELRRQLKVLDADREQKGRELAELQTRLSLEEQREEERGKEVFILKQKLAETQ-TLSMTQKRLVES-------ESGWRSCERELTAQLQEARGCEKKLQDEAKNLSVRAQAAQESAAQCSLQLSEAQGRLTATEAELTRAEASKRDLEFRLSSLQSALTRTLG-----------------------------IGASGSTPDNT------MGSGAVSPEGGGTPLPPAQPELDPDTLRSGLRDFLQELRDAHRQRDDAQCQLMTLQRELEEQKLERECAENRSTQLQNSLKECQEGKRGLDDRLTSTQILLQQQEDAVKRVDRERRALADRVRELERSLHTAEMEKKHTQEQLNKQRATEARLEAERKRLREALEAAEARATRVELGRRSLEGELQRLKLGLGDREAESQASQERHDCLLRQVAEGEAQVSLLQTEVDRLSQALLKAQEGEAALKQKVTTLSQSLQE-------------------AAADHS--STQTRLTALQKTLS-------------------LVEQDKRLLQVSGSTRGGWRSLA-------ETQHSIQKAQTERAAVEERLLALQRAVALLETEKKDAERQAARLEKDKDALRNTLDKVERQKLKCEEGSMRLSAEKTRLDRSLNAVEQELQEAQQQMLMLQVTM---EQAHSG--CEGLLRQRDEAQQEAEKLRNSCKDLERTLSTRERAHRHRVKGLEEQVSTLKEQLQQEMKRRQPPL 1630 HSP 2 Score: 127.102 bits (318), Expect = 1.491e-28 Identity = 103/361 (28.53%), Postives = 178/361 (49.31%), Query Frame = 1
Query: 292 SNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDT 1374
S D P +P V++I+ ++ D SS + S+ L+ EN L+ L +E+ L + +RD LAIK+ AI+E+L + +E + + SLA Q ++LR++LD++ Y+RKL A + Q +QA+L+++LQ K+ Q + R G +E+ Q+ S SE+ + +D + LE + L+EEQ +S SL + A+LR+QL++A AN+ L+ D++RL+ + + + ELEQK+ DW+ +E +F + E R+ + W VV F+R ++KSS D+ ++ + S Q R S +D+
Sbjct: 39 SPDDPPACLPARVREIVTKNLSD-----------------------SSECSPQAGEMSSLMSLQEENRVLQGELARLEDLLAHSRADRDELAIKYGAISERLEQALRSE------TGEGEADSQASRSLAQQNVELRRRLDEEQAAYRRKLTAYQEGQQRQAQLVQKLQAKVLQYKKRCGDLEQKLQEKS---SELEKC--------------------------SDSSSSLEEALLHLEEEQQRSSSLSAVNAMLREQLEQAGLANEALSRDIRRLTADWTKAREELEQKESDWRREEESFHSYFSSEHGRLLTFWRQVVGFRRHVCEMKSS---DVRGRLLSAQSSAQKFRKQLSEIDS 338
BLAST of Rootletin-2 vs. Planmine SMEST
Match: SMESG000081227.1 (SMESG000081227.1) HSP 1 Score: 4200.97 bits (10894), Expect = 0.000e+0 Identity = 2203/2203 (100.00%), Postives = 2203/2203 (100.00%), Query Frame = 1
Query: 109 MSSANRDERLEQVAQKLNKFTDIFYQRVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA 6717
MSSANRDERLEQVAQKLNKFTDIFYQRVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVSNASEELSNANSLASQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKEAREEDIERLIAEREELRNEFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVRRELEELRSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLRNRSPSPGRRSRSVSPEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTQLELLRRGLEGELQRLKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSLKKTLDKLEKEKNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA
Sbjct: 1 MSSANRDERLEQVAQKLNKFTDIFYQRVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVSNASEELSNANSLASQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKEAREEDIERLIAEREELRNEFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVRRELEELRSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLRNRSPSPGRRSRSVSPEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTQLELLRRGLEGELQRLKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSLKKTLDKLEKEKNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA 2203
BLAST of Rootletin-2 vs. Planmine SMEST
Match: SMESG000081227.1 (SMESG000081227.1) HSP 1 Score: 4165.15 bits (10801), Expect = 0.000e+0 Identity = 2192/2203 (99.50%), Postives = 2192/2203 (99.50%), Query Frame = 1
Query: 109 MSSANRDERLEQVAQKLNKFTDIFYQRVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA 6717
MSSANRDERLEQVAQ RVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVSNASEELSNANSLASQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKEAREEDIERLIAEREELRNEFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVRRELEELRSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLRNRSPSPGRRSRSVSPEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTQLELLRRGLEGELQRLKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSLKKTLDKLEKEKNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA
Sbjct: 1 MSSANRDERLEQVAQ-----------RVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVSNASEELSNANSLASQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKEAREEDIERLIAEREELRNEFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVRRELEELRSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLRNRSPSPGRRSRSVSPEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTQLELLRRGLEGELQRLKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSLKKTLDKLEKEKNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA 2192
BLAST of Rootletin-2 vs. Planmine SMEST
Match: SMESG000081227.1 (SMESG000081227.1) HSP 1 Score: 4091.19 bits (10609), Expect = 0.000e+0 Identity = 2161/2203 (98.09%), Postives = 2161/2203 (98.09%), Query Frame = 1
Query: 109 MSSANRDERLEQVAQKLNKFTDIFYQRVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA 6717
MSSANRDERLEQVAQ RVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVSNASEELSNANSLASQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQK FQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKEAREEDIERLIAEREELRNEFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVRRELEELRSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLRNRSPSPGRRSRSVSPEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTQLELLRRGLEGELQRLKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSLKKTLDKLEKEKNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA
Sbjct: 1 MSSANRDERLEQVAQ-----------RVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVSNASEELSNANSLASQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQK-------------------------------FQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKEAREEDIERLIAEREELRNEFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVRRELEELRSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLRNRSPSPGRRSRSVSPEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTQLELLRRGLEGELQRLKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSLKKTLDKLEKEKNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKRELNLNKSNRGLKNDICDIKSILEKNSNNISKTSFDNLLYEPEIRRMKDILSESGYSNNCNVISTMKQSQRPGSRLQSNSLSRQNISSASPTRA 2161
BLAST of Rootletin-2 vs. Planmine SMEST
Match: SMESG000081227.1 (SMESG000081227.1) HSP 1 Score: 3755.3 bits (9737), Expect = 0.000e+0 Identity = 1973/1984 (99.45%), Postives = 1973/1984 (99.45%), Query Frame = 1
Query: 109 MSSANRDERLEQVAQKLNKFTDIFYQRVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVXXXXXXXXXXXXXXXQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNS 6060
MSSANRDERLEQVAQ RVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVSNASEELSNANSLASQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKEAREEDIERLIAEREELRNEFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVRRELEELRSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLRNRSPSPGRRSRSVSPEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTQLELLRRGLEGELQRLKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNS
Sbjct: 1 MSSANRDERLEQVAQ-----------RVENVLADRDNQGYLKYNSGRIVSNTSPGIGGFDLSNGDKPQKMPEVVKDIILRDFGDTDEDEDSIKDLRMPKPNSQNTQSSSRLQTYGNGLDSVTQLKAENATLKDSLFNVEEELLRLKNERDNLAIKFNAINEKLNKTFTAEKCGDRRVSNASEELSNANSLASQTIQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLRSEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKEAREEDIERLIAEREELRNEFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVRRELEELRSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLRNRSPSPGRRSRSVSPEKGRVSSRNSVEFNFSEDRKRVGRFGDVNQYSESVIPGSDLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTQLELLRRGLEGELQRLKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNS 1973
BLAST of Rootletin-2 vs. Planmine SMEST
Match: SMESG000071494.1 (SMESG000071494.1) HSP 1 Score: 1085.86 bits (2807), Expect = 0.000e+0 Identity = 805/1998 (40.29%), Postives = 1246/1998 (62.36%), Query Frame = 1
Query: 691 IQLRKQLDDDHREYKRKLAAQHDHQIKQAELIKRLQQKLEQLEGRNGLVEKLNQQNSKLR-SEISRLKNHFQTTTSDLNRRIDIAENHLKSAETDKNMDLESVVNELKEEQSKSMSLLQMTALLRDQLDEATNANQGLTEDVQRLSEENSFLKSELEQKDMDWKDDEATFSRFLIGEQNRIKSLWNAVVNFKRQFNDIKSSNERDLHQLRVNIEQSTQSLRLACSNLDTNHVNRLSQLQFQLDTEKNNCSQLENSLSKMKEEFRKTETQYQKQIESLNEQFVHVNRSNESLTKELADKEKVLTTLHKLRNGMNGDLDNSIYNNDDSATRQLIIDTDAVHQALRDIAQLVMNDVDQVDDSPWMQDDYLDESKTTGQLKPTLSINSLHSNRSVSPTRPSKRSHFNSGSLDRNRVYRNKSPVSIADSTCAAVRSALHKRALQVQDLTSKINSAKNNHNSVKKQLDDSENERRNLEKQFIELRSEYDSNHRELDDIQRECERMRHTISMLEEDKLKLDKSRMNSYEECKSYKQDMEKLKTLNYELQRDKENLTDNCQDLDRNLERQTKEVERLTKSIENSESKSSRLKEEISSLKESLNRALLEKEVLEQENSVLTDSLNKTEVLKAEYEVKANKFKTEEARLRDKFHQLESMNHFLVKENSEFKTIIDQTESEKHRLSGEKKALEQEKYGIREELMRVENEKEELNQMKDGLHQSMQNVEKSYENLQDELSKLNYEKGQLETANVTLQRERNALSTELLQARRDAERLSAAVQKSMKDKEVLAKEKIDLISQLTTFEHELRENADAIYVLQEEKEQLDGSLYESQQNISQLEAKIEALESNLQQLERKRSIIFDEKQRLQHEFDVELQKLSKAKESLQIKLNESEKEWNKILRSEKXXXXXXXXXXXXXXXXXXXXFMKYKEEIKLQFQEEIDDLRHRLNRDKEELAQEIITIQRERDDCLLEAEMGKQHAINLLEQEKMSMYEKISQLTDLLRTSESDLERTRNECEIRAQQDQNTIQTFNGDLKKFRLQFEQIHIDHDREIKNLQCAYKELENQKYQDMRENEELKSLLKIAEETRDNLRQDLSESMGKIRETEDQRERLRRELMDEKRNYFEVKKELETIQLSNKELREKLKTSEMQKIDIQRQLQDLQNKLSILEEQKQVLQKEVKDTRYNLQDTEKARVDVXXXXXXXXSQVKKLDTERGKLVNEVSGLQVRVATDENKEVEARRENFGLKQKVIESEATKEELSKQLYQSLRKNEELEEILNSKEKTTKQYYDEVLKDYKSLEESKLNLENQLEITNHNFEELNSTLSTKENRISLLENQINILDQKRKGAENRLATIHSHLRKLIGFRQQICQTLXXXXXXXXXXXXXXXXEKGR---------VSSRNSVE--FNFSEDRK--RVGRFGDVN--QYSESVIPGS------DLDPEAVRIALRDITQHIVSIERERDDMEIKAKNSALKSDETSVQLDQALQRINQLQKNFGEVEEDKKGIDSRLSSAQTALMMQEETIHRNERERKSLIDKVGKLERQLAHVETEKKYLQERVDKMRTGESYHEEERRGLIKAVDDAENRCTXXXXXXXXXXXXXXXXKMGFNDKETENQVLRDRVDALTKQISDLESKAQSLQLTIDRLSMNLARTEEEENTQKDKVHQLNLSLSEHQGNLQSMQDKLVQLQSTLASSEHDRRVLQERLESVKHNLSEAKSQNHTLVDRMKATQQELMESESRKHEIEGEIKRLSQILSQRQEIEQELQSKIHRSAMEKNLLTERLNSLTASLAGLESERRDIEKVHIKTEKEKNSXXXXXXXXXXXXNRSEESINQSLLKRSEFDEFTRRLEDENEVLHRQVQKLQNQLAEAEQCHAQRIMELTSRIKNEMLSEIDRLKSALNSTEKTLQFRERSHRQKVKSLEEQINILKDQLSQELKKR-----ELNLNKSNRGLKNDICDIKSILEKNSNNISK-TSFDNLLYEPEIRRMKDILSESG 6600
++LRK+L+++H EY+RKL D Q KQA+L++RLQ+K+ Q + EK + SK++ + K + + T+ N +EN N+DLES + +L+EEQ K+ L + L++QL +AT +NQ LT D+ +LSEE + ELEQ++ W+++E +F+ +L E + +++L +NF+RQF ++K+S ER+++ L+ + + L+ ACSNL N + S+ Q + E + LEN L + E +T+Y+ ++ L + + ++ L + +K++ LT L +++NG D I N +D ATR LI DT+++HQALR+I+Q+V+ND DY D T + T+ N NRS P++ H + + D+T AAV+SA++K++LQ+Q+L SK+NS+K + + K+Q+DD+ENERR LE Q + +R E +S R+ DD RE +R ++ +++ ++ +L+K R + ++ + ++E+LK+ N+ELQR +E L D +D ++LERQ KE ER +SI+ E K SR KE++ + KE++N+ LEKEVL QE + D+L++ E+ KAE E++ NK +T E L + +L S L + +E I Q E E+ L EK+ LEQEK G+++EL+R E E L+ K Q ++ +E + E L++ELS+LN EK L LQR+++AL+ ELLQ RR+ ER + +V K+KE L KEK +L+ Q+T E E R+ ++ I L ++EQL+ +LY++QQ I QLE + E LE Q+L K+ + E RL+ EF +E +K+ ++E L + + +KE+ ++ E+++ ED+ERL E R+ +EE+ +F E DD+ ++K+E+AQEI+TIQRERDD LL AE KQ +++LLEQEK ++ EK+ + L++ ES+L+R + E R +QD+ I + +LK FR QFE +H+ E+K+L K+L K Q ++E +L + LKIAEETRDNLR+++ E K++E E+ +E L+RE+ + KR E ++E E + SN+ LR+K+K E ++ID+ RQ+ D + K+++ +EQ ++EV + R NL+D EKAR+DV+REL+ELR +K+LDTERGKL EV+ LQ RVA DE KE EARRENFGLKQKV+E+EA++E + K L + R +LE +L SK++ + +DY+ L +++ +L+ + + EL LS E R+S LE+ I ++ +K E +LA+IHS LR+LIGFRQ+ T+R+R+ S +GR VS + + + D K + R G + Q S P + D++PEAVR+ALR+ Q +V ER+RDD +A++ + E Q + A R+ QLQ+ + EEDKKGID RLSSAQTALMMQEETI RNER+RK++ +K+ +R A +E+EK+ L++R++K R ++ EEE + KA+++AENR TQL+L +R LEG+LQR+KM DKETE +VL DRV++L KQI DLE K+QSLQLTIDR+S+ LA+TEEE + KDK+ QLN+SLS H L+ +Q+K+ QLQ L SSE DRR+L+ERLES K L EAK QN+ L++R++ Q +L +SE+R+ E+EG ++ + ++ QRQE EQEL K + EKN L ER+NS+ +LA E+E+++I K H K EK++++LKK+L K+E++K ++EE ++++ +RSE D+ RRLEDEN L RQV LQNQLAEAEQ H +ME+ SR + EM E++ L+++ E+TL+ RER+HRQ+VK LEEQI+ LKDQL+ E+++R + KSN+ + D++ +L+ + ++K D +L E E RR+ + + G
Sbjct: 35 LELRKRLEEEHNEYRRKLIVFQDSQQKQAQLVQRLQKKVLQYK------EKCTELESKMQFGDYETRKTKYGSPTN--NGYGSRSENPYD------NLDLESTLIKLEEEQKKTNYLTEFNERLQEQLTQATQSNQNLTRDISKLSEEWQRSREELEQREKIWRNEEMSFNDYLASEHSNLQNLQRNTINFRRQFIELKASTEREINNLKNEFNRQARCLQTACSNLSCNMKSAESKQQLSTERESRDKLNLENQLREKNRELTDYQTRYECEMTELQHRVKELTVLSDKLKIQNLEKDRALTALQRIKNG---DTAGEI-NMEDKATRVLIEDTESMHQALRNISQVVLND-----------SDYFDAEDTGFE---TVRKN----NRS-----PNQLKHRH-----------------LPDATYAAVQSAINKKSLQIQELKSKLNSSKESCTNFKRQIDDNENERRRLENQVLAMRDEIESLRRDKDDSFREADRFKNALNITSNERSQLEKIRSSLNDQIEQQLTEIERLKSANHELQRLREALEDEQEDTKKDLERQIKESERCQRSIDVLEDKISRFKEDVVNYKEAINKYQLEKEVLVQEKDEIGDALSRCEISKAELEIEVNKRQTIEVNLEENISKLSSEIEELNDKRAENHRTIKQLEHERSSLLNEKRCLEQEKSGLKDELVRSEQEALGLSNEKAIQRQRIEQLEINTERLEEELSELNREKLDLTEQIGCLQRQKSALAEELLQCRRELERSNNSVNNLSKEKEYLTKEKGELVVQVTACERENRQQSEVIASLNSDREQLEATLYDAQQLIIQLETRKEQLEGENQELIVKKENLNGELVRLRQEFQLEYEKVVNSREQLNCRYQQMDKEYKMAIQQERDSHAEDVERLTKINESNRHGSENEREELIHRFNMERDDMIQNYEQEKQEMAQEIMTIQRERDDSLLMAENEKQQSLSLLEQEKCAINEKLIKTQFELQSVESELDRIKKESSNRQEQDKQNIAGLSSELKSFRSQFEDKCQNHEMEVKSLNNGIKDLTLMKDQALKEVHDLHTGLKIAEETRDNLRREIMEMNRKLKEAEEAKEHLKREINELKRGLCEEQREKENVINSNENLRKKIKDVETERIDLHRQVTDSKQKVAVQDEQLVNSKQEVNELRNNLKDVEKARLDVKRELQELRRHIKELDTERGKLTKEVNDLQTRVARDEEKEDEARRENFGLKQKVVETEASREAVRKDLANAQRHIVDLENVLQSKDRDFSSMVESSRRDYRKLADARNSLQQVYDTMVADNNELRIALSGAEGRVSALESHIARVEGAKKEIEFKLASIHSSLRRLIGFRQENVVTIRSRNNSKSPV-------RGRSVSPLRSRPVSPTKGFDNTYATTTDGKGSPIPRTGSPSSKQRQLSRSPSNCDFNPVDINPEAVRLALREFVQQLVDAERDRDDAFAQARSLESRLKEQEEQNEYAENRLQQLQQALCDAEEDKKGIDGRLSSAQTALMMQEETIRRNERDRKAMAEKLSNYDRTFASMESEKRQLEDRLNKFRHHDARLEEEHKQSKKAIENAENRITQLQLAKRSLEGDLQRMKMALTDKETETEVLDDRVNSLLKQIQDLEGKSQSLQLTIDRMSVALAKTEEEGSFHKDKMQQLNMSLSTHSQQLEQLQNKISQLQKALGSSEQDRRLLEERLESSKGALHEAKHQNNLLMERIQIIQSDLNDSENRRSELEGLNRQSNTLIVQRQEAEQELNQKYQKLNSEKNTLQERVNSMQRNLALAEAEKQEIIKNHGKLEKDRSALKKSLGKVERQKLKTEEIASKTVFERSELDQILRRLEDENCELQRQVGILQNQLAEAEQAHCHHLMEINSRHRQEMSMEMEHLRASNVQIERTLEGRERAHRQRVKGLEEQISTLKDQLTHEMQRRMDSGYYESTRKSNQ--YDSTGDLRHVLDSSLTRVAKDPQLDAMLLETEARRLDESIFMCG 1965 The following BLAST results are available for this feature:
BLAST of Rootletin-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Rootletin-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Rootletin-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of Rootletin-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 4
BLAST of Rootletin-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Rootletin-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Rootletin-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Rootletin-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Rootletin-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Rootletin-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Rootletin-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Rootletin-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Rootletin-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Rootletin-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30023882 ID=SMED30023882|Name=Rootletin-2|organism=Schmidtea mediterranea sexual|type=transcript|length=6811bpback to top protein sequence of SMED30023882-orf-1 >SMED30023882-orf-1 ID=SMED30023882-orf-1|Name=SMED30023882-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2208bp MSSANRDERLEQVAQKLNKFTDIFYQRVENVLADRDNQGYLKYNSGRIVSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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