Carbonic anhydrase

Overview
NameCarbonic anhydrase
Smed IDSMED30023854
Length (bp)1335
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Carbonic anhydrase (SMED30023854) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Carbonic anhydrase (SMED30023854) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30023854

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30023854h1SMcG0020756 dd_Smed_v4_9270_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30023854h1SMcG0020756 dd_Smed_v4_9270_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30023854h1SMcG0020756 dd_Smed_v4_9270_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023854h1SMcG0020756 dd_Smed_v4_9270_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30023854h1SMcG0020756 dd_Smed_v4_9270_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Carbonic anhydrase vs. Ensembl Human
Match: CA7 (carbonic anhydrase 7 [Source:HGNC Symbol;Acc:HGNC:1381])

HSP 1 Score: 150.984 bits (380), Expect = 6.121e-42
Identity = 99/269 (36.80%), Postives = 144/269 (53.53%), Query Frame = 2
Query:  266 NWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
             WGY  GQ   GPS W +L      G RQSPI+I+    +Y   L+   +S    ++ S+T   H   +  N +D+  +  GG   G  +    H+HWG  + +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +VNNFRP  P++       RVV ASF
Sbjct:    6 GWGY--GQD-DGPSHWHKL-YPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYM-VRFKGTKAQFSCFNPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKG------RVVKASF 262          
BLAST of Carbonic anhydrase vs. Ensembl Human
Match: CA7 (carbonic anhydrase 7 [Source:HGNC Symbol;Acc:HGNC:1381])

HSP 1 Score: 129.798 bits (325), Expect = 1.059e-34
Identity = 79/211 (37.44%), Postives = 116/211 (54.98%), Query Frame = 2
Query:  440 SVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            S+T   H   +  N +D+  +  GG   G  +    H+HWG  + +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +VNNFRP  P++       RVV ASF
Sbjct:    4 SITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYM-VRFKGTKAQFSCFNPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKG------RVVKASF 206          
BLAST of Carbonic anhydrase vs. Ensembl Human
Match: CA2 (carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373])

HSP 1 Score: 126.331 bits (316), Expect = 8.296e-33
Identity = 88/274 (32.12%), Postives = 139/274 (50.73%), Query Frame = 2
Query:  260 SDNWGYKEGQSFKGPSQWWQ-LPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF---GDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFN 1063
            S +WGY +     GP  W +  P     G+RQSP+DI      Y   LK   +S   + +  +    H  ++  + + +  +  GG  +G  + +  H+HWGS +  GSEH +   ++  E HLV ++   Y  F +A   P+GL V+G F +VG   P +  V   + S +K K  S + +   P+ +LP E ++Y+ Y GSLTTPP  + V W VL+    +S +Q+  FR L F   G+PE   +V+N+RP  P++       R + ASF 
Sbjct:    2 SHHWGYGK---HNGPEHWHKDFP--IAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDS-IKTKGKSADFTNFDPRGLLP-ESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPE-ELMVDNWRPAQPLKN------RQIKASFK 260          
BLAST of Carbonic anhydrase vs. Ensembl Human
Match: CA1 (carbonic anhydrase 1 [Source:HGNC Symbol;Acc:HGNC:1368])

HSP 1 Score: 122.094 bits (305), Expect = 3.050e-31
Identity = 89/275 (32.36%), Postives = 137/275 (49.82%), Query Frame = 2
Query:  257 SSDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNF--NDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNL---VFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            +S +WGY +     GP QW +L      G  QSP+DI    T +   LK   +S   +    +    H  S ++NF  NDN  +  GG  +   +    H+HWGS+N  GSEH + G ++  E H+  ++   YSS  +A+   +GL VIG   +VG  NP +  V  A+++ +K K      +   P  +LP  L +++ Y GSLT PP  ++V W + +    +S +QL+ FR+L   V GD     + +N RP  P++       R V ASF
Sbjct:    2 ASPDWGYDDKN---GPEQWSKL-YPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGH--SFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQA-IKTKGKRAPFTNFDPSTLLPSSL-DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV-PMQHNNRPTQPLKG------RTVRASF 261          
BLAST of Carbonic anhydrase vs. Ensembl Human
Match: CA1 (carbonic anhydrase 1 [Source:HGNC Symbol;Acc:HGNC:1368])

HSP 1 Score: 122.094 bits (305), Expect = 3.050e-31
Identity = 89/275 (32.36%), Postives = 137/275 (49.82%), Query Frame = 2
Query:  257 SSDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNF--NDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNL---VFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            +S +WGY +     GP QW +L      G  QSP+DI    T +   LK   +S   +    +    H  S ++NF  NDN  +  GG  +   +    H+HWGS+N  GSEH + G ++  E H+  ++   YSS  +A+   +GL VIG   +VG  NP +  V  A+++ +K K      +   P  +LP  L +++ Y GSLT PP  ++V W + +    +S +QL+ FR+L   V GD     + +N RP  P++       R V ASF
Sbjct:    2 ASPDWGYDDKN---GPEQWSKL-YPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGH--SFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQA-IKTKGKRAPFTNFDPSTLLPSSL-DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV-PMQHNNRPTQPLKG------RTVRASF 261          
BLAST of Carbonic anhydrase vs. Ensembl Celegans
Match: cah-5 (Putative carbonic anhydrase 5 [Source:UniProtKB/Swiss-Prot;Acc:Q10462])

HSP 1 Score: 110.923 bits (276), Expect = 4.031e-27
Identity = 85/267 (31.84%), Postives = 123/267 (46.07%), Query Frame = 2
Query:  257 SSDNWGYKEGQSFKGPSQWWQLPNTTCGGQ-RQSPIDIVPKFTIYWEDLKLPIISRINSINHSV--------TIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIP---PKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPI 1015
            S   WGY E     GP  W       C    +QSPIDI         D+   ++ R++ +N+ +        T    FA  + ++     +  GG      K    H HWG ++ +GSEH +    +P E HLV    GL  + ++A   P+GL V+G F  +   N  +    S I   +     S N +E+     K +LPL+   +YRYEGSLTTP C++ VIWTVL     IS  QL + R L   + E  K   N+RP+ P+
Sbjct:   24 SDHGWGYDENN---GPDTW----QGKCQNHLKQSPIDIRAP------DVDYALLHRMHFLNYDMDGKIELSNTGRTLFAGGFESWQHKQPMIQGGGLKHRYKLAQFHLHWGQNDAVGSEHAMGSLHYPAELHLVHVREGL--TLKEALSRPDGLAVVGVF--LAKTNDPVANKFSPISERLHDLRHSGNKTELKNFRTKYVLPLDTEAFYRYEGSLTTPDCSEAVIWTVLAEPMAISSHQLHLLRQL--HNKELVKSDKNYRPLQPL 271          
BLAST of Carbonic anhydrase vs. Ensembl Celegans
Match: cah-3 (Putative carbonic anhydrase 3 [Source:UniProtKB/Swiss-Prot;Acc:Q27504])

HSP 1 Score: 95.5153 bits (236), Expect = 2.910e-22
Identity = 75/236 (31.78%), Postives = 111/236 (47.03%), Query Frame = 2
Query:  323 PNTTCGGQRQSPIDI-----VPKFT---IYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG-NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRP 1003
            PN    GQ QSPI+I       K T   I + +   PI   I +  HSV +     S      ++ +I  GG +   + V  H+HWG ++  GSEH L G R+P E HLV           Q    P  L V+G F ++G    A++     +      +T +  V  +   + LP    +++RYEGSLTTPPC++ V WT+      ++ DQL +FR +   D E   +  N+RP
Sbjct:   15 PNRWPTGQHQSPINIDLGEVERKDTHDGIKFVNYDHPIQGDIVNNGHSVQMTPELRS------EHPEIYGGGLDQVYRLVQYHFHWGENDNEGSEHTLGGLRYPAELHLV----------HQGVEDPGKLAVVGVFLQLGKEGKALSNEERVLGKLCNPETVT-RVENVRLSEKLPANKRSFWRYEGSLTTPPCSEIVTWTIFTEPVTVTHDQLELFRQVQ--DIEKRPIKKNYRP 231          
BLAST of Carbonic anhydrase vs. Ensembl Celegans
Match: cah-1 (Putative carbonic anhydrase-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20781])

HSP 1 Score: 89.7373 bits (221), Expect = 8.779e-20
Identity = 73/279 (26.16%), Postives = 120/279 (43.01%), Query Frame = 2
Query:  215 FVIRSDSVLDVHESSSDNWGYKEGQSFKGP-------SQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLK------LPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPI 1006
             +I +  +  +  S +  W Y +   F GP         WW        G+ QSPIDI P   ++   +K      LP++S   +    V +   ++S   + N      +G    ++   + +H G  N  GSEH + G RFPME  LV+Y+  LY +F  AS SP+G+ ++      G       +  +   + +  K   V +++  P  +LP    +   YEGSLT+P C + V W +L     I ++    + +L       E   +  NFR I
Sbjct:   12 LIILTCHISPLKSSQNYQWSY-DSDVFGGPHFWGLVEKDWWMCKK----GRLQSPIDIQPDRLLFDASVKPVRLDKLPVVSEFVNTGQMVRVRIGYSSKKPSVNITSGPLYGYRYRVQ--RIDFHMGRKNENGSEHTINGRRFPMEVQLVAYNTDLYPNFTSASKSPHGIAILSVLVDFGPETNQELIKLTIATASISYKDQRVQLADFEPWRLLPFT-RDIITYEGSLTSPGCHETVTWIILNQPIFIKKEHFEEWSHLYLSMEGAEKVPVAPNFRKI 282          
BLAST of Carbonic anhydrase vs. Ensembl Celegans
Match: cah-4 (Carbonic AnHydrase [Source:UniProtKB/TrEMBL;Acc:Q21614])

HSP 1 Score: 78.9518 bits (193), Expect = 1.647e-16
Identity = 65/216 (30.09%), Postives = 93/216 (43.06%), Query Frame = 2
Query:  338 GGQRQSPIDIVPKFTIYWEDL----KLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGC----LKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPL-ELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLV 958
              QRQSPIDIVP+      D+     L I  +       +  E  F    +N   N       N            H HWGS++  GSEH L G +   E H V ++   Y SF  A   P+GL V+G F + G  N     +   ++      T      +   + +LP  +   +  Y GSLTTPP  + VIWT+     ++S  QL+V RN++
Sbjct:    3 AAQRQSPIDIVPQHVCCDTDVCKADALNIDYKSGDCCDVLVSEGGF---LVNVKRNCGTFLTANHLPSSKFALAQFHAHWGSNSKEGSEHFLDGKQLSGEVHFVFWNTS-YESFNVALSKPDGLAVVGVFLKEGKYNDNYHGLIDTVRKATGNATPIAMPKDFHIEHLLPSPDKREFVTYLGSLTTPPYNECVIWTLFTEPVEVSFGQLNVLRNII 214          
BLAST of Carbonic anhydrase vs. Ensembl Celegans
Match: cah-2 (Putative carbonic anhydrase-like protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q18932])

HSP 1 Score: 80.1073 bits (196), Expect = 2.229e-16
Identity = 71/284 (25.00%), Postives = 115/284 (40.49%), Query Frame = 2
Query:  263 DNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYL-NFNDNWKITFGGNGC------LKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGD---PEFGKLVNNFRPIFPIEKSTDYILRVVYASFNYSSKLMT 1084
            D WG   G         W++      GQ QSP++I P   +Y   L +PI    N +            + + +  +   I   G         L  ++VH+        GSEH +   RFP E  L++Y+  LY +F  A  SP GL  +     +G          +     +  K  + N+++  P  +LP +  +Y  YEGSLT P C + V W +L +   I+ D L ++  +   +   PE   +   +RP+  +        R+V  + N  SK  T
Sbjct:   18 DFWGLLHGD--------WRM---CTAGQMQSPVNIDPSQLLYDPHL-MPINIEGNIVEAVFENTGQLPVVTVKDLPNRPTINITGGPTMPYRYKLHQISVHFGRADEGEKGSEHTVDRVRFPAEIQLLAYNSALYPNFSVAMTSPRGLLAVSVIVDIGKTTSVELRRLTVASQSINYKGQTTNLTDFQPSALLP-KTSHYVTYEGSLTFPGCHETVTWVILNNPIYITNDDLQIWNEMQKTETKQPEPSYMTPAYRPLKSLNG------RLVRTNINVGSKQST 282          
BLAST of Carbonic anhydrase vs. Ensembl Fly
Match: CAH1 (gene:FBgn0027844 transcript:FBtr0080539)

HSP 1 Score: 131.724 bits (330), Expect = 4.221e-35
Identity = 88/267 (32.96%), Postives = 140/267 (52.43%), Query Frame = 2
Query:  260 SDNWGYKEGQSFKGPSQWW-QLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTI--EKHFASIYLNFNDNWKITFG--GNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGD-------PEF-GKLVNNFRPIFPIEK 1021
            S +WGY E     GP+ W  + P  +  G RQSP+DI P       +L +  +       H+ ++    +   + +N  D+ ++T G  G+   K    H HWG ++  GSEH + G  +  E HLV ++   Y SF +A+ +P+GL V+G F + G ++  +  V S ++  +             P  +LP ++  Y+ YEGSLTTPPC+++VIW V ++  ++S+DQL+  RNL   D        EF GK++NNFRP  P+ K
Sbjct:    2 SHHWGYTEEN---GPAHWAKEYPQAS--GHRQSPVDITPSSAKKGSELNVAPLKWKYVPEHTKSLVNPGYCWRVDVNGADS-ELTGGPLGDQIFKLEQFHCHWGCTDSKGSEHTVDGVSYSGELHLVHWNTTKYKSFGEAAAAPDGLAVLGVFLKAGNHHAELDKVTSLLQFVLHKGDRVTLPQGCDPGQLLP-DVHTYWTYEGSLTTPPCSESVIWIVFKTPIEVSDDQLNAMRNLNAYDVKEECPCNEFNGKVINNFRPPLPLGK 261          
BLAST of Carbonic anhydrase vs. Ensembl Fly
Match: CAH2 (gene:FBgn0027843 transcript:FBtr0076001)

HSP 1 Score: 111.309 bits (277), Expect = 4.997e-27
Identity = 86/289 (29.76%), Postives = 141/289 (48.79%), Query Frame = 2
Query:  194 FGIIIASFVIRSDSVLDVHESSSDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIIS-RINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAV-------HWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSE-IPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDY 1033
            F I+IA  +I +  VL      + ++GY EG+   GP  W +     C G+ QSPI+I     +  +  KL   + ++   N  +T   H   + +++N++   +  G    +   +       H+HWG ++ IGSE  +    +P E H+V  +   Y  F  A    +G+ V+ FF++VG  +       + + S +  K  SVN++  +P  + +   + +Y+ Y GSLTTPPC++ V W    +  DI+E QL+ FR L   D     L NNFRPI P+   T Y
Sbjct:    9 FAIVIAPILICASLVL------AQDFGY-EGR--HGPEHWSE-DYARCSGKHQSPINIDQVSAVEKKFPKLEFFNFKVVPDNLQMTNNGHTVLVKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHVVLRNLE-YPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDRKGKSVNMTNPLPLGEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLTAND---DHLKNNFRPIQPLNDRTLY 283          
BLAST of Carbonic anhydrase vs. Ensembl Fly
Match: CAH9 (gene:FBgn0039486 transcript:FBtr0085133)

HSP 1 Score: 97.8265 bits (242), Expect = 1.782e-22
Identity = 83/274 (30.29%), Postives = 126/274 (45.99%), Query Frame = 2
Query:  257 SSDNWGYKEGQSFKGPSQW-WQLPNTTCGGQRQSPIDIVPKFTI-----------YWEDLKLPIISRINSINHSVTIEK----HFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKL-----KTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPI 1015
            SS  +GY E      P+Q  W   +  C G+ QSPI I    T            Y   L  P+    N    S+TI K         +L +    K+     G  +   +H+HWG  N  GSEH +   R+ ME H+V  +   Y++  +A   P+G  V+GFF+ +  +  A  +    I  H+ L     +  ++NV+      I  +++  +Y Y+GSLTTPPC++ V W +      IS  Q+S FR L   D + G LV+NFR + P+
Sbjct:   21 SSHVFGYSE------PNQRRWARHHGHCAGKTQSPIAITTSRTTAIHMPAVDMIGYHNLLPYPLKMINNGHTVSITIPKVNVTEVGEDFLPYIRGAKLP----GEFEVEGLHFHWGDKNNRGSEHVINDIRYTMEMHIVHRNKK-YATIGEALNHPDGAAVLGFFFNLDEDEGAGLVT---INRHLHLIADANQEATLNVTFSLSSLIAGVDVDKFYTYKGSLTTPPCSEAVTWILFPDPIPISPKQISRFRQL--SDTQDGALVDNFRTLQPV 278          
BLAST of Carbonic anhydrase vs. Ensembl Fly
Match: CAH2 (gene:FBgn0027843 transcript:FBtr0333381)

HSP 1 Score: 96.6709 bits (239), Expect = 1.843e-22
Identity = 58/165 (35.15%), Postives = 88/165 (53.33%), Query Frame = 2
Query:  542 HWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSE-IPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDY 1033
            H+HWG ++ IGSE  +    +P E H+V  +   Y  F  A    +G+ V+ FF++VG  +       + + S +  K  SVN++  +P  + +   + +Y+ Y GSLTTPPC++ V W    +  DI+E QL+ FR L   D     L NNFRPI P+   T Y
Sbjct:   41 HFHWGENDTIGSEDLINNRAYPAELHVVLRNLE-YPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDRKGKSVNMTNPLPLGEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLTAND---DHLKNNFRPIQPLNDRTLY 201          
BLAST of Carbonic anhydrase vs. Ensembl Fly
Match: CAH4 (gene:FBgn0039235 transcript:FBtr0084732)

HSP 1 Score: 90.1225 bits (222), Expect = 6.472e-20
Identity = 70/243 (28.81%), Postives = 112/243 (46.09%), Query Frame = 2
Query:  326 NTTCGGQRQSPIDI---------VPK--FTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYR----VGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILP-LELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPI 1006
            N  CG +RQSPI +         VPK  F  Y + L  P+    + IN+ +T+             +  I+  G    +   +H+HWGS+   GSEH L G  +  E H+V  +   Y S ++A + PNG  V+  F R      +  PA+ M+   + S  KL         +  +D+   ++   Y+ Y+GSLTTPPC + VIW V  +  D+ ++    F  L   D    +++N +R +
Sbjct:   31 NVKCG-ERQSPIALWSCNAITCNVPKLKFLNYHKSLCDPL----SVINNGLTVLMRIPKTVDGSRPSLCISTEGQQVFEADQLHFHWGSALSKGSEHCLDGNYYDGEVHIVHKNAS-YKSNKEAGLQPNGFAVLALFIRNLEDPNIETPAMNMICKQVSSITKLDDSCPLEDSMALQDLFASIDSQKYFTYQGSLTTPPCAEAVIWFVFPTPLDVPKELWKHFWQL--RDSRDQRVLNTYREL 265          
BLAST of Carbonic anhydrase vs. Ensembl Zebrafish
Match: cahz (carbonic anhydrase [Source:NCBI gene;Acc:30331])

HSP 1 Score: 139.813 bits (351), Expect = 5.345e-38
Identity = 95/270 (35.19%), Postives = 136/270 (50.37%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQ-LPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGK--LVNNFRPIFPIEKSTDYILRVVYASFN 1063
            WGY       GP  W +  P     G RQSPIDIVP    +   LK   +    +   S+    H   +    +DN     GG   G  +    H+HWGSS+  GSEH + GT+FP E HLV ++   Y +F +A+  P+GL V+G F ++G  NP +  V  A+   +K K      +   PK +LP  L +Y+ YEGSLTTPP  ++V W VL+    +S  Q++ FR+L+F         +V+N+RP  P++       R V ASF 
Sbjct:    5 WGYGPAD---GPESWAESFP--IANGPRQSPIDIVPTQAQHDPSLKHLKLKYDPATTKSILNNGHSFQVDFVDDDNSSTLAGGPITGIYRLRQFHFHWGSSDDKGSEHTIAGTKFPCELHLVHWNTK-YPNFGEAASKPDGLAVVGVFLKIGAANPRLQKVLDALDD-IKSKGRQTTFANFDPKTLLPASL-DYWTYEGSLTTPPLLESVTWIVLKEPISVSPAQMAKFRSLLFSSEGETPCCMVDNYRPPQPLKG------RKVRASFK 260          
BLAST of Carbonic anhydrase vs. Ensembl Zebrafish
Match: ca2 (carbonic anhydrase II [Source:ZFIN;Acc:ZDB-GENE-031219-5])

HSP 1 Score: 134.806 bits (338), Expect = 3.780e-36
Identity = 97/273 (35.53%), Postives = 142/273 (52.01%), Query Frame = 2
Query:  260 SDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFND--NWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF-GDPEFG-KLVNNFRPIFPIEKSTDYILRVVYASF 1060
            +D+WGY +     GP +W +       G RQSPIDI    T Y  D KL  +      + S+ I+ +  S  ++F D  N     GG   G  +    H+HWGS++  GSEH + G  +P E HLV ++   Y SF+ A   P+GL V+G F ++G +NP +  +  A+ + +K K          P  +LP  L +Y+ Y GSLTTPP  ++V W V +    +S  Q+  FR+L+F GD E    +VNN+RP  P++       RVV ASF
Sbjct:    2 ADHWGYDK---HNGPDKWGE-SYPIANGSRQSPIDIKSSTTTY--DEKLTPLKLKYDPSTSLDIQNNGHSFQVSFVDDQNSSTLTGGPVTGTFRLKQFHFHWGSADDKGSEHTVNGKCYPAELHLVHWNTK-YPSFKDAVDKPDGLAVVGVFLKIGADNPKLQKILDAMDA-IKSKGKQTPFPNFDPSVLLPSSL-DYWTYLGSLTTPPLLESVTWIVCKQSISVSSAQMKRFRSLLFSGDGEKACCMVNNYRPPQPLKG------RVVRASF 259          
BLAST of Carbonic anhydrase vs. Ensembl Zebrafish
Match: ca7 (carbonic anhydrase VII [Source:ZFIN;Acc:ZDB-GENE-040426-1786])

HSP 1 Score: 134.035 bits (336), Expect = 8.212e-36
Identity = 95/275 (34.55%), Postives = 139/275 (50.55%), Query Frame = 2
Query:  257 SSDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPV----AVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPE---FGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            +  +WGY E     GPS W +       G RQSPIDIVP   ++  D KL  IS   +   S++I  +  S+ + F D  + +    G L+ +      H+HWGS    GSEH + G  F  E HLV ++   Y SF +A+ +P+GL V+G F   G  + A+  +  A+   ++ K          PK +LP  L  Y+ Y GSLTTPP  ++V W VL+    +SE Q+  FR L+F   E     ++ NN+RP  P++       R+V ASF
Sbjct:    2 TGHHWGYGEDN---GPSAWHK-DYPIAEGNRQSPIDIVPSEAVF--DAKLSPISLSYNNCTSLSISNNGHSVVVEFVDTDERSVITGGPLENMYRLKQFHFHWGSKGCCGSEHTVAGKTFVSELHLVHWNANKYKSFSEAAAAPDGLAVLGIFLETGDEHRALHQITDALYM-VRFKGSLAEFKGFNPKCLLPNSL-EYWTYPGSLTTPPLYESVTWIVLKEPIYVSEKQMGKFRTLLFNGEEEEDRNRMENNYRPPQPLKG------RMVRASF 262          
BLAST of Carbonic anhydrase vs. Ensembl Zebrafish
Match: ca4b (carbonic anhydrase IV b [Source:ZFIN;Acc:ZDB-GENE-080815-5])

HSP 1 Score: 128.257 bits (321), Expect = 3.822e-33
Identity = 104/312 (33.33%), Postives = 143/312 (45.83%), Query Frame = 2
Query:  200 IIIASFVIRSDSVLDVHESSSDNWGYK-----EGQSFKGPSQWWQLPNTTCGGQRQSPIDIVP------------KFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCL-KPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYR----VGLNNPAITMVASAI---KSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPI-----FPIEKSTDYILRV 1045
            I+  +F+  S   +    +SS  W Y+        S  GP  W  +    CG  +QSPI+IV             +FT Y E L   I++      H+V I         N  D  KI     G   K   +H HWG +   GSEH + G +FPME H+V      Y+S +QA    +G+ V+GFFY        N  AI    + I   +S+  L   S+++  IP +D     L  Y+RYEGSLTTP C + V+WT+      +S++QLS F NL F D     +VN FRPI      P+  S  YI  V
Sbjct:   15 ILRMNFLCLSTLAILCRLASSAEWCYQTQVTCSNHSCIGPDDWATVA-AACGNNKQSPINIVTNKASTDSRLTPVQFTDYQERLNAVIVNN----GHTVQI---------NLPDRAKINGANLGSTYKAQQLHLHWGKNGGPGSEHTIDGEKFPMELHVVHIK-EEYNSLEQAVGDSSGVAVLGFFYEESENANKNYDAIINSLTNITHPESNAALGAISLDML-IPNED-----LDKYFRYEGSLTTPGCAEAVVWTIFEKTIPLSKEQLSAFSNLTFSDG--AAMVNTFRPIQLRYDRPVYYSRSYIFHV 303          
BLAST of Carbonic anhydrase vs. Ensembl Zebrafish
Match: ca4a (carbonic anhydrase IV a [Source:NCBI gene;Acc:555196])

HSP 1 Score: 127.102 bits (318), Expect = 6.940e-33
Identity = 105/305 (34.43%), Postives = 155/305 (50.82%), Query Frame = 2
Query:  239 LDVHESSSDNWGYKEGQSF----KGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGC--LKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVG-LNNPAITMVASAIKS------HMKLKTFSVNVSEIPPKDILP-LELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGK-LVNNFRPIFPIEKSTDYILRVVYASFNYSSKLMTNFVLPAFI 1108
            L +H  +  +W Y+   S     KGP +W ++ N  CG  RQSPI+IV K T   E L     +   ++    T++ +  S+ ++      I+ GGN     K V  H HWG S+  GSEH + G ++PME H+V      Y   + A   P+G+ V+GFFY V    N    + A A++S      +  L+  S+N      + ILP + + NYYRY+GSLTTP CT+ V+WTV      +  +QL  F +L F D   GK +V  FRP+ P         RVVY S +  + L++ F+L A +
Sbjct:   12 LILHACTGADWCYQTQVSCDSHCKGPEKWREV-NADCGKDRQSPINIVTKQTKLDERLTPFRFTGYQTVFDG-TLKNNGHSVQVSIPVPATIS-GGNLAEPYKAVQFHLHWGISSGPGSEHTIDGEQYPMELHIVHMK-QKYIRIEDALKDPSGVAVLGFFYEVSSTTNRKYDLFAHALRSVQNTNGNTTLRKISLN------QLILPEVNMTNYYRYDGSLTTPGCTEAVVWTVFEKPIPLDSEQLQAFSSLKFRD---GKPMVGTFRPVQPRNG------RVVYRS-SGGTLLVSVFLLMASV 296          
BLAST of Carbonic anhydrase vs. Ensembl Xenopus
Match: proca1 (protein interacting with cyclin A1 [Source:Xenbase;Acc:XB-GENE-1005546])

HSP 1 Score: 134.42 bits (337), Expect = 9.447e-36
Identity = 100/277 (36.10%), Postives = 138/277 (49.82%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQ-LPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIIS--RINSIN-----HSVTIEKHFASIYLNFNDNWKITFGG-NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRN--LVFGDPEFGK--LVNNFRPIFPIEKSTDYILRVVYASF 1060
            WGY E     GPS+W    P     G RQSPIDIV    ++   L   +IS     SIN     HSV +E      + +++D   IT G   G  +    H+HWG+    GSEH + G  +P E HLV ++   YSSF +A+ +P+GL VIG F   G  +  +  +  A+   +K K       +  PK +LP     Y+ Y GSLTTPP  ++V W VL+    +SE Q+  FR   L  G+ E  +  +VNNFRP  P++       R V ASF
Sbjct:    7 WGYGEED---GPSEWHHYFP--IAEGNRQSPIDIVSNQAVFNPSLNPLVISYDHCTSINLSNNGHSVMVE------FDDYDDKTVITGGPLEGSYRLKQFHFHWGTQRNSGSEHTVDGKSYPCELHLVHWNARAYSSFGEAAAAPDGLVVIGVFLETGGQHSGLNRLTDALYM-VKFKGTKTQFDDFNPKCLLPSSF-EYWTYPGSLTTPPLNESVTWIVLKEPIKVSEKQMERFRKTLLFSGEEEEQRIHMVNNFRPPQPLKG------RKVQASF 264          
BLAST of Carbonic anhydrase vs. Ensembl Xenopus
Match: proca1 (protein interacting with cyclin A1 [Source:Xenbase;Acc:XB-GENE-1005546])

HSP 1 Score: 128.257 bits (321), Expect = 1.169e-33
Identity = 95/266 (35.71%), Postives = 133/266 (50.00%), Query Frame = 2
Query:  302 PSQWWQ-LPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIIS--RINSIN-----HSVTIEKHFASIYLNFNDNWKITFGG-NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRN--LVFGDPEFGK--LVNNFRPIFPIEKSTDYILRVVYASF 1060
            PS+W    P     G RQSPIDIV    ++   L   +IS     SIN     HSV +E      + +++D   IT G   G  +    H+HWG+    GSEH + G  +P E HLV ++   YSSF +A+ +P+GL VIG F   G  +  +  +  A+   +K K       +  PK +LP     Y+ Y GSLTTPP  ++V W VL+    +SE Q+  FR   L  G+ E  +  +VNNFRP  P++       R V ASF
Sbjct:    7 PSEWHHYFP--IAEGNRQSPIDIVSNQAVFNPSLNPLVISYDHCTSINLSNNGHSVMVE------FDDYDDKTVITGGPLEGSYRLKQFHFHWGTQRNSGSEHTVDGKSYPCELHLVHWNARAYSSFGEAAAAPDGLVVIGVFLETGGQHSGLNRLTDALYM-VKFKGTKTQFDDFNPKCLLPSSF-EYWTYPGSLTTPPLNESVTWIVLKEPIKVSEKQMERFRKTLLFSGEEEEQRIHMVNNFRPPQPLKG------RKVQASF 256          
BLAST of Carbonic anhydrase vs. Ensembl Xenopus
Match: ca13 (carbonic anhydrase XIII [Source:NCBI gene;Acc:779902])

HSP 1 Score: 126.331 bits (316), Expect = 8.860e-33
Identity = 92/275 (33.45%), Postives = 141/275 (51.27%), Query Frame = 2
Query:  266 NWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEK-HFASIYLNFNDNWKITFGGN--GCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNN---PAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF----GDPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
             WGY++     GP  W  L      G RQSPI+I+ +  IY   L+ P+    +  +  V I   H  ++  +  D+  +  GG   G  +    H+HWGSS+  GSEH++ G  +  E H+V ++   +SSF +A+ +P+GL V+G F +VG  N     IT    AI+S  K   F    +   P  +LP   M+++ Y GSLT PP  ++V W VL+    IS +QL+ FR+L+F     + E   + +N RP+ P++       R V ASF
Sbjct:    4 QWGYED---HNGPEVWHDL-FPLANGDRQSPINIITRDAIYDPSLQ-PLQVNYDHDSAKVVINTGHTFTMEFDDGDDTSVLRGGPFIGSYRLRQFHFHWGSSDGHGSEHKVDGMDYAAELHIVHWNSEKFSSFVEAACAPDGLAVLGVFLKVGEPNRYIERITDTFGAIRSKGKQSPF----TNFDPSCLLPAS-MDFWTYPGSLTVPPLLESVTWVVLKEPISISHEQLARFRSLLFTKDTAEIEACCMKSNHRPVQPLKN------RKVRASF 262          
BLAST of Carbonic anhydrase vs. Ensembl Xenopus
Match: ca5b (carbonic anhydrase VB, mitochondrial [Source:NCBI gene;Acc:733981])

HSP 1 Score: 123.635 bits (309), Expect = 2.074e-31
Identity = 82/249 (32.93%), Postives = 138/249 (55.42%), Query Frame = 2
Query:  338 GGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNW-KITFGGNGCLKPVAV---HWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF---GDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFN 1063
            GG RQSPI+I  + +++   L  P+ ++ +  N  + I  +  S ++ ++D+  K T  G     P  +   H+HWG +N  GSEH +    FP E HLV ++C  Y +F++A + PNGL VIG F +VG ++  +  +   + S ++ K      +      +LP    +Y+ Y GSLTTPP T++V W +++   ++   QL+VFR+L+F   G+ E   +V+NFRP+ P+      + R V++SF 
Sbjct:   52 GGSRQSPINIRIRDSVFHPQLA-PLHTQYDP-NTCLYIWNNGYSFFVEYDDSTDKSTVSGGPLENPFRLKQFHFHWGRNNDWGSEHTVDSRVFPAELHLVHWNCSKYRTFEEAIMEPNGLAVIGVFLKVGKHHEKLQKLVDILPS-VRYKDALTEFNYFDSSCLLP-SCGDYWTYSGSLTTPPLTESVTWIIMKKPIEVDHSQLAVFRSLLFTAVGEEE-RYMVDNFRPLQPL------MNRTVHSSFE 289          
BLAST of Carbonic anhydrase vs. Ensembl Xenopus
Match: ca5b (carbonic anhydrase VB, mitochondrial [Source:NCBI gene;Acc:733981])

HSP 1 Score: 123.25 bits (308), Expect = 3.242e-31
Identity = 82/249 (32.93%), Postives = 138/249 (55.42%), Query Frame = 2
Query:  338 GGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNW-KITFGGNGCLKPVAV---HWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF---GDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFN 1063
            GG RQSPI+I  + +++   L  P+ ++ +  N  + I  +  S ++ ++D+  K T  G     P  +   H+HWG +N  GSEH +    FP E HLV ++C  Y +F++A + PNGL VIG F +VG ++  +  +   + S ++ K      +      +LP    +Y+ Y GSLTTPP T++V W +++   ++   QL+VFR+L+F   G+ E   +V+NFRP+ P+      + R V++SF 
Sbjct:   62 GGSRQSPINIRIRDSVFHPQLA-PLHTQYDP-NTCLYIWNNGYSFFVEYDDSTDKSTVSGGPLENPFRLKQFHFHWGRNNDWGSEHTVDSRVFPAELHLVHWNCSKYRTFEEAIMEPNGLAVIGVFLKVGKHHEKLQKLVDILPS-VRYKDALTEFNYFDSSCLLP-SCGDYWTYSGSLTTPPLTESVTWIIMKKPIEVDHSQLAVFRSLLFTAVGEEE-RYMVDNFRPLQPL------MNRTVHSSFE 299          
BLAST of Carbonic anhydrase vs. Ensembl Mouse
Match: Car7 (carbonic anhydrase 7 [Source:MGI Symbol;Acc:MGI:103100])

HSP 1 Score: 148.673 bits (374), Expect = 2.476e-41
Identity = 97/269 (36.06%), Postives = 143/269 (53.16%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASFN 1063
            WGY  GQ   GPS W +L      G RQSPI+I+    +Y   L+   +     ++ S+T   H   +  N +D+  +  GG   G  +   +H+HWG    +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +V+NFRP  P++       RVV ASF 
Sbjct:    7 WGY--GQD-DGPSNWHKL-YPIAQGDRQSPINIISSQAVYSPSLQPLELFYEACMSLSITNNGHSVQVDFNDSDDRTVVSGGPLEGPYRLKQLHFHWGKKRDMGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAAAAPDGLAVVGVFLETGDEHPSMNRLTDALYM-VRFKDTKAQFSCFNPKCLLPTS-RHYWTYPGSLTTPPLSESVTWIVLREPIRISERQMEKFRSLLFTSEDDERIHMVDNFRPPQPLKG------RVVKASFQ 263          
BLAST of Carbonic anhydrase vs. Ensembl Mouse
Match: Car7 (carbonic anhydrase 7 [Source:MGI Symbol;Acc:MGI:103100])

HSP 1 Score: 130.954 bits (328), Expect = 2.868e-35
Identity = 78/212 (36.79%), Postives = 116/212 (54.72%), Query Frame = 2
Query:  440 SVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASFN 1063
            S+T   H   +  N +D+  +  GG   G  +   +H+HWG    +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +V+NFRP  P++       RVV ASF 
Sbjct:    4 SITNNGHSVQVDFNDSDDRTVVSGGPLEGPYRLKQLHFHWGKKRDMGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAAAAPDGLAVVGVFLETGDEHPSMNRLTDALYM-VRFKDTKAQFSCFNPKCLLPTS-RHYWTYPGSLTTPPLSESVTWIVLREPIRISERQMEKFRSLLFTSEDDERIHMVDNFRPPQPLKG------RVVKASFQ 207          
BLAST of Carbonic anhydrase vs. Ensembl Mouse
Match: Car7 (carbonic anhydrase 7 [Source:MGI Symbol;Acc:MGI:103100])

HSP 1 Score: 130.954 bits (328), Expect = 2.868e-35
Identity = 78/212 (36.79%), Postives = 116/212 (54.72%), Query Frame = 2
Query:  440 SVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASFN 1063
            S+T   H   +  N +D+  +  GG   G  +   +H+HWG    +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +V+NFRP  P++       RVV ASF 
Sbjct:    4 SITNNGHSVQVDFNDSDDRTVVSGGPLEGPYRLKQLHFHWGKKRDMGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAAAAPDGLAVVGVFLETGDEHPSMNRLTDALYM-VRFKDTKAQFSCFNPKCLLPTS-RHYWTYPGSLTTPPLSESVTWIVLREPIRISERQMEKFRSLLFTSEDDERIHMVDNFRPPQPLKG------RVVKASFQ 207          
BLAST of Carbonic anhydrase vs. Ensembl Mouse
Match: Car12 (carbonic anhydrase 12 [Source:MGI Symbol;Acc:MGI:1923709])

HSP 1 Score: 127.487 bits (319), Expect = 1.604e-32
Identity = 92/283 (32.51%), Postives = 135/283 (47.70%), Query Frame = 2
Query:  290 SFKGPS--QWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRIN-SINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYI-GSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF----GDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFNYSSKLMTNFVLPAFILL 1114
            ++ GP+  + W     +CGG  QSPID+      Y   L        N S+   + +     S+ LN N +  I        +   +H HWG+ N   GSEH + G  F  E H+V Y+  LY  F  AS    GL V+     +G  NP+   + S ++ H+K K   V +     +++LP     YYRYEGSLTTPPC   V+WTV R+   IS++QL      ++     DP   +++NNFR +   ++      R+VY SF     L+TN  L   I+L
Sbjct:   33 TYVGPAGEKNWSKKYPSCGGLLQSPIDLHSDILQYDASLAPLQFQGYNVSVEKLLNLTNDGHSVRLNLNSDMYIQGLQPHHYRAEQLHLHWGNRNDPHGSEHTVSGKHFAAELHIVHYNSDLYPDFSTASDKSEGLAVLAVLIEIGSANPSYDKIFSHLQ-HVKYKGQQVLIPGFNIEELLPESPGEYYRYEGSLTTPPCYPTVLWTVFRNPVQISQEQLLALETALYFTHMDDPTPREMINNFRQVQKFDE------RLVYISFR--QGLLTNTGLSLGIIL 306          
BLAST of Carbonic anhydrase vs. Ensembl Mouse
Match: Car12 (carbonic anhydrase 12 [Source:MGI Symbol;Acc:MGI:1923709])

HSP 1 Score: 125.176 bits (313), Expect = 8.558e-32
Identity = 86/265 (32.45%), Postives = 127/265 (47.92%), Query Frame = 2
Query:  290 SFKGPS--QWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRIN-SINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYI-GSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF----GDPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            ++ GP+  + W     +CGG  QSPID+      Y   L        N S+   + +     S+ LN N +  I        +   +H HWG+ N   GSEH + G  F  E H+V Y+  LY  F  AS    GL V+     +G  NP+   + S ++ H+K K   V +     +++LP     YYRYEGSLTTPPC   V+WTV R+   IS++QL      ++     DP   +++NNFR +   ++      R+VY SF
Sbjct:   33 TYVGPAGEKNWSKKYPSCGGLLQSPIDLHSDILQYDASLAPLQFQGYNVSVEKLLNLTNDGHSVRLNLNSDMYIQGLQPHHYRAEQLHLHWGNRNDPHGSEHTVSGKHFAAELHIVHYNSDLYPDFSTASDKSEGLAVLAVLIEIGSANPSYDKIFSHLQ-HVKYKGQQVLIPGFNIEELLPESPGEYYRYEGSLTTPPCYPTVLWTVFRNPVQISQEQLLALETALYFTHMDDPTPREMINNFRQVQKFDE------RLVYISF 290          
BLAST of Carbonic anhydrase vs. UniProt/SwissProt
Match: sp|P43166|CAH7_HUMAN (Carbonic anhydrase 7 OS=Homo sapiens OX=9606 GN=CA7 PE=1 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 2.940e-41
Identity = 99/269 (36.80%), Postives = 144/269 (53.53%), Query Frame = 2
Query:  266 NWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
             WGY  GQ   GPS W +L      G RQSPI+I+    +Y   L+   +S    ++ S+T   H   +  N +D+  +  GG   G  +    H+HWG  + +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +VNNFRP  P++       RVV ASF
Sbjct:    6 GWGY--GQD-DGPSHWHKL-YPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYM-VRFKGTKAQFSCFNPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKG------RVVKASF 262          
BLAST of Carbonic anhydrase vs. UniProt/SwissProt
Match: sp|Q9ERQ8|CAH7_MOUSE (Carbonic anhydrase 7 OS=Mus musculus OX=10090 GN=Ca7 PE=1 SV=2)

HSP 1 Score: 148.673 bits (374), Expect = 1.732e-40
Identity = 97/269 (36.06%), Postives = 143/269 (53.16%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASFN 1063
            WGY  GQ   GPS W +L      G RQSPI+I+    +Y   L+   +     ++ S+T   H   +  N +D+  +  GG   G  +   +H+HWG    +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +V+NFRP  P++       RVV ASF 
Sbjct:    7 WGY--GQD-DGPSNWHKL-YPIAQGDRQSPINIISSQAVYSPSLQPLELFYEACMSLSITNNGHSVQVDFNDSDDRTVVSGGPLEGPYRLKQLHFHWGKKRDMGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAAAAPDGLAVVGVFLETGDEHPSMNRLTDALYM-VRFKDTKAQFSCFNPKCLLPTS-RHYWTYPGSLTTPPLSESVTWIVLREPIRISERQMEKFRSLLFTSEDDERIHMVDNFRPPQPLKG------RVVKASFQ 263          
BLAST of Carbonic anhydrase vs. UniProt/SwissProt
Match: sp|Q92051|CAHZ_DANRE (Carbonic anhydrase OS=Danio rerio OX=7955 GN=cahz PE=1 SV=2)

HSP 1 Score: 139.813 bits (351), Expect = 4.035e-37
Identity = 95/270 (35.19%), Postives = 136/270 (50.37%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQ-LPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGK--LVNNFRPIFPIEKSTDYILRVVYASFN 1063
            WGY       GP  W +  P     G RQSPIDIVP    +   LK   +    +   S+    H   +    +DN     GG   G  +    H+HWGSS+  GSEH + GT+FP E HLV ++   Y +F +A+  P+GL V+G F ++G  NP +  V  A+   +K K      +   PK +LP  L +Y+ YEGSLTTPP  ++V W VL+    +S  Q++ FR+L+F         +V+N+RP  P++       R V ASF 
Sbjct:    5 WGYGPAD---GPESWAESFP--IANGPRQSPIDIVPTQAQHDPSLKHLKLKYDPATTKSILNNGHSFQVDFVDDDNSSTLAGGPITGIYRLRQFHFHWGSSDDKGSEHTIAGTKFPCELHLVHWNTK-YPNFGEAASKPDGLAVVGVFLKIGAANPRLQKVLDALDD-IKSKGRQTTFANFDPKTLLPASL-DYWTYEGSLTTPPLLESVTWIVLKEPISVSPAQMAKFRSLLFSSEGETPCCMVDNYRPPQPLKG------RKVRASFK 260          
BLAST of Carbonic anhydrase vs. UniProt/SwissProt
Match: sp|Q8UWA5|CAH2_TRIHK (Carbonic anhydrase 2 OS=Tribolodon hakonensis OX=151740 GN=ca2 PE=2 SV=3)

HSP 1 Score: 130.954 bits (328), Expect = 8.615e-34
Identity = 92/272 (33.82%), Postives = 142/272 (52.21%), Query Frame = 2
Query:  260 SDNWGYKEGQSFKGPSQWWQ-LPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKH-FASIYLNFNDNWKITFGG-NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGK--LVNNFRPIFPIEKSTDYILRVVYASF 1060
            S  WGY +     GP +W +  P     G RQSPIDI  K   Y + LK   +    + +  +    H F   + + ND+  +T G  +G  +    H+HWG+S+  GSEH + G  +P E HLV ++   Y+SF +A+  P+GL V+G F ++G +NP +  +  A+ + +K K    + +   P  +LP  L  Y+ Y GSLTTPP  ++V W V +    +S +Q+  FR+L+F   E     +VNN+RP  P++       R V ASF
Sbjct:    2 SHGWGYAD---HNGPQKWCENFP--IANGPRQSPIDIQTKGASYDDTLKPLKLKYDPTTSLDILNNGHSFQVTFADDNDSSMLTEGPISGKYRLKQFHFHWGASDGKGSEHTVDGKCYPAELHLVHWNTK-YASFGEAANKPDGLAVVGVFLQIGEDNPKLQKILDAMDA-IKSKGKQTSFTNFDPTCLLPKSL-EYWTYPGSLTTPPLYESVTWIVCKQPISVSSEQMKKFRSLLFTAEEEKACCMVNNYRPPQPLKD------RKVCASF 259          
BLAST of Carbonic anhydrase vs. UniProt/SwissProt
Match: sp|P83299|CAH1_CHIHA (Carbonic anhydrase 1 OS=Chionodraco hamatus OX=36188 GN=ca1 PE=1 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 2.140e-33
Identity = 93/273 (34.07%), Postives = 144/273 (52.75%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQW-WQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPV----AVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF---GDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFN 1063
            WGY       GP +W    P     G RQSPIDI+P    Y   LK P+  + +  N  + I  +  S  + F D+   +    G +  V      H+HWG+SN  GSEH + GT++P E HLV ++   Y SF +A+  P+GL V+G F ++G  N ++  V  A    ++ K    + ++  P  +LP   ++Y+ Y+GSLTTPP  ++V W V +    +S +Q++ FR+L+F   G+PE   +V+N+RP  P++       R V ASF 
Sbjct:    4 WGYGPTD---GPDKWVSNFP--IADGPRQSPIDILPGGASYDSGLK-PLSLKYDPSN-CLEILNNGHSFQVTFADDSDSSTLKEGPISGVYRLKQFHFHWGASNDKGSEHTVAGTKYPAELHLVHWNTK-YPSFGEAASKPDGLAVVGVFLKIGDANASLQKVLDAFND-IRAKGKQTSFADFDPSTLLP-GCLDYWTYDGSLTTPPLLESVTWIVCKEPISVSCEQMAKFRSLLFSAEGEPECC-MVDNYRPPQPLKG------RHVRASFQ 259          
BLAST of Carbonic anhydrase vs. TrEMBL
Match: A0A452QQI4 (Carbonic anhydrase 7 OS=Ursus americanus OX=9643 GN=CA7 PE=3 SV=1)

HSP 1 Score: 158.303 bits (399), Expect = 1.170e-41
Identity = 99/266 (37.22%), Postives = 145/266 (54.51%), Query Frame = 2
Query:  278 KEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASFN 1063
            +EG+  +GPSQW +L      G RQSPI+IV    +Y   LK   +S    I+ S+    H   +  N +D+  +  GG  +G  +    H+HWG  + +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +VNNFRP  P++       RVV ASF 
Sbjct:    4 EEGRRGRGPSQWHKL-YPIAQGDRQSPINIVSSQAVYSPSLKPLELSYEACISLSIANNGHSVQVDFNDSDDRTVVTGGPLDGPYRLKQFHFHWGKKHSVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYM-VRFKGTRAQFSCFNPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPISISERQMEKFRSLLFTSEDDERIHMVNNFRPPQPLKG------RVVKASFR 260          
BLAST of Carbonic anhydrase vs. TrEMBL
Match: U6D7N1 (Carbonic anhydrase 7 (Fragment) OS=Neovison vison OX=452646 GN=CAH7 PE=2 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 1.588e-41
Identity = 103/268 (38.43%), Postives = 147/268 (54.85%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            WGY  GQ+  GPSQW +L      G RQSPI+IV    +Y   LK   +S    I+ S+T   H   +  N +D+  +  GG  +G  +    H+HWG  + +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +VNNFRP  P++       RVV ASF
Sbjct:    1 WGY--GQN-DGPSQWHKL-YPIAQGDRQSPINIVSSQAVYSPSLKPLELSYEACISLSITNNGHSVQVDFNDSDDRTVVTGGPLDGPYRLKQFHFHWGKKHSVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGNEHPSMNRLTDALYM-VRFKGTKAQFSCFNPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPISISERQMEKFRSLLFTSEDDERIHMVNNFRPPQPLKG------RVVKASF 256          
BLAST of Carbonic anhydrase vs. TrEMBL
Match: M3WHK2 (Carbonic anhydrase 7 OS=Felis catus OX=9685 GN=CA7 PE=3 SV=2)

HSP 1 Score: 157.918 bits (398), Expect = 1.668e-41
Identity = 103/269 (38.29%), Postives = 147/269 (54.65%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASFN 1063
            WGY  GQ+  GPSQW +L      G RQSPI+IV    +Y   LK   +S    I+ S+T   H   +  N +D+  +  GG  +G  +    H+HWG  + +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +VNNFRP  P++       RVV ASF 
Sbjct:    7 WGY--GQN-DGPSQWHKL-YPIAQGDRQSPINIVSSQAVYSPSLKPLELSYEACISLSITNNGHSVQVDFNDSDDRTVVTGGPLDGPYRLKQFHFHWGKKHSVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYM-VRFKGTKAQFSCFNPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPISISERQMEKFRSLLFTSEDDERIHMVNNFRPPQPLKG------RVVKASFQ 263          
BLAST of Carbonic anhydrase vs. TrEMBL
Match: A0A2U3VFI9 (carbonic anhydrase 7 OS=Odobenus rosmarus divergens OX=9708 GN=CA7 PE=3 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 1.795e-41
Identity = 102/268 (38.06%), Postives = 147/268 (54.85%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            WGY  GQ+  GPSQW +L      G RQSPI+IV    +Y   LK   +S    I+ S+    H   +  N +D+  +  GG  +G  +   +H+HWG  + +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +VNNFRP  P++       RVV ASF
Sbjct:    7 WGY--GQN-DGPSQWHKL-YPIAQGDRQSPINIVSSQAVYSPSLKPLELSYEACISLSIANNGHSVQVDFNDSDDRTVVTGGPLDGPYRLKQLHFHWGKKHSVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMHRLTDALYM-VRFKGTKAQFSCFNPKSLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPISISERQMEKFRSLLFTSEDDERIHMVNNFRPPQPLKG------RVVKASF 262          
BLAST of Carbonic anhydrase vs. TrEMBL
Match: A0A2Y9IBR8 (carbonic anhydrase 7 OS=Neomonachus schauinslandi OX=29088 GN=CA7 PE=3 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 2.788e-41
Identity = 100/268 (37.31%), Postives = 145/268 (54.10%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG--DPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            WGY +     GPSQW +L      G RQSPI+IV    +Y   LK   +S    I+ S+    H   +  N +D+  +  GG  +G  +   +H+HWG  + +GSEH + G  FP E HLV ++   YS+F +A+ +P+GL V+G F   G  +P++  +  A+   ++ K      S   PK +LP    +Y+ Y GSLTTPP +++V W VLR    ISE Q+  FR+L+F   D E   +VNNFRP  P++       RVV ASF
Sbjct:    7 WGYGQ---IDGPSQWHKL-YPIAQGDRQSPINIVSSQAVYSPSLKPLELSYEACISLSIANNGHSVQVDFNDSDDRTVVTGGPLDGPYRLKQLHFHWGKKHSVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYM-VRFKGTKAQFSCFNPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPISISERQMEKFRSLLFTSEDDERIHMVNNFRPPQPLKG------RVVKASF 262          
BLAST of Carbonic anhydrase vs. Ensembl Cavefish
Match: cahz (carbonic anhydrase-like [Source:NCBI gene;Acc:103030997])

HSP 1 Score: 142.895 bits (359), Expect = 2.900e-39
Identity = 96/258 (37.21%), Postives = 137/258 (53.10%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQ-LPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMV---ASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF-GDPEFGK-LVNNFRPIFPIE 1018
            WGY E     GPS W +  P     G RQSPIDI+P    +   LK   +    S +  +    H   +    +D+  +  GG   G  +    H+HWG ++  GSEH + GT+FP E HLV ++   Y +F +A   P+GL V+G F ++G  NP++  V     AIKS  K  TFS       PK +LP  L  Y+ YEGSLTTPP  ++V W VLR    +S  Q++ FR+L+F  D E  + +V+N+RP  P++
Sbjct:    5 WGYSE---HDGPSHWCENFP--VANGPRQSPIDIIPSQAQFDSKLKQLKLKYDPSTSKGILNNGHSFQVDFADDDDRSVLTGGPVTGTYRLKQFHFHWGGADDRGSEHTVGGTKFPCELHLVHWNTK-YPNFGEAVSKPDGLAVVGVFLKIGGANPSLQKVLDACDAIKSKGKQTTFS----NFDPKTLLPATLQ-YWTYEGSLTTPPLHESVTWIVLRDPISVSPAQMAKFRSLLFSADGETPRCMVDNYRPPQPLK 251          
BLAST of Carbonic anhydrase vs. Ensembl Cavefish
Match: ca7 (carbonic anhydrase 7 [Source:NCBI gene;Acc:103041882])

HSP 1 Score: 130.954 bits (328), Expect = 8.565e-35
Identity = 89/256 (34.77%), Postives = 128/256 (50.00%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFND--NWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPE---FGKLVNNFRPIFPI 1015
            WGY E     GPS W +       G RQSPI+IVP   +Y  D  LP IS       S+ I  +  S+ + F+D  +  +  GG  N   +    H+HWG     GSEH + G  +  E HLV ++   Y SF +A  + +GL V+G F  +G  +  +  +  A+   +K K    +  +  PK +LP  L  Y+ Y GSLTTPP  ++V W VL    ++SE Q+  FR L+F   E     ++ NNFRP  P+
Sbjct:    6 WGYGEDD---GPSAWSK-DYPIAEGPRQSPINIVPDEAVY--DANLPPISLNYDNCTSINISNNGHSVVVEFDDADDRSVIQGGPLNNAYRLKQFHFHWGGKGCHGSEHTVSGKTYTSELHLVHWNAARYGSFGEAVAASDGLAVLGVFLEIGDEHRGLHKITDALYM-VKFKGTVADFRDFNPKCLLPRSL-GYWTYPGSLTTPPLYESVTWIVLAEPIEVSEKQMGKFRTLLFSGEEEEVRKRMENNFRPPQPL 253          
BLAST of Carbonic anhydrase vs. Ensembl Cavefish
Match: ca5a (carbonic anhydrase 5B, mitochondrial [Source:NCBI gene;Acc:103039663])

HSP 1 Score: 130.183 bits (326), Expect = 2.807e-34
Identity = 82/255 (32.16%), Postives = 132/255 (51.76%), Query Frame = 2
Query:  284 GQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKP----VAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFG---KLVNNFRPIFPIEKST 1027
            G+  K     WQ P    GG+RQSPIDI  + +++   LK P++ + +       I  +  S  + ++D    +    G L+        H+HWG +N  G+EH +    +P E HLV ++   YS F++A +  NGL VIG F +VG  +  +  +  A+ + ++ K   V  +      +LP    +Y+ Y GSLTTPP T+ V W +++   ++S DQL+VFR+L+F   E      +VNNFR   P++  T
Sbjct:   10 GEWIKKMHPMWQEPLAIPGGERQSPIDISVRKSMFDPQLK-PLVMKYDP-RTCQQIWNNGYSFLVEYDDTTDKSTLQGGPLEDQFRLCQFHFHWGENNKWGAEHTVDHLLYPAELHLVHWNADRYSLFEEAVMEDNGLAVIGVFLKVGKRHEGLQKLVDALPA-VRHKDSVVEFTRFDASGLLPENTQDYWTYAGSLTTPPLTEAVTWIIMKQPIEVSHDQLAVFRSLLFTSAEEDVQKSMVNNFRVQQPLKGRT 261          
BLAST of Carbonic anhydrase vs. Ensembl Cavefish
Match: ca5a (carbonic anhydrase 5B, mitochondrial [Source:NCBI gene;Acc:103039663])

HSP 1 Score: 129.798 bits (325), Expect = 6.394e-34
Identity = 80/245 (32.65%), Postives = 129/245 (52.65%), Query Frame = 2
Query:  314 WQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKP----VAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFG---KLVNNFRPIFPIEKST 1027
            WQ P    GG+RQSPIDI  + +++   LK P++ + +       I  +  S  + ++D    +    G L+        H+HWG +N  G+EH +    +P E HLV ++   YS F++A +  NGL VIG F +VG  +  +  +  A+ + ++ K   V  +      +LP    +Y+ Y GSLTTPP T+ V W +++   ++S DQL+VFR+L+F   E      +VNNFR   P++  T
Sbjct:   53 WQEPLAIPGGERQSPIDISVRKSMFDPQLK-PLVMKYDP-RTCQQIWNNGYSFLVEYDDTTDKSTLQGGPLEDQFRLCQFHFHWGENNKWGAEHTVDHLLYPAELHLVHWNADRYSLFEEAVMEDNGLAVIGVFLKVGKRHEGLQKLVDALPA-VRHKDSVVEFTRFDASGLLPENTQDYWTYAGSLTTPPLTEAVTWIIMKQPIEVSHDQLAVFRSLLFTSAEEDVQKSMVNNFRVQQPLKGRT 294          
BLAST of Carbonic anhydrase vs. Ensembl Cavefish
Match: ca7 (carbonic anhydrase 7 [Source:NCBI gene;Acc:103041882])

HSP 1 Score: 128.642 bits (322), Expect = 7.047e-34
Identity = 86/248 (34.68%), Postives = 125/248 (50.40%), Query Frame = 2
Query:  293 FKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFND--NWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPE---FGKLVNNFRPIFPI 1015
            F GPS W +       G RQSPI+IVP   +Y  D  LP IS       S+ I  +  S+ + F+D  +  +  GG  N   +    H+HWG     GSEH + G  +  E HLV ++   Y SF +A  + +GL V+G F  +G  +  +  +  A+   +K K    +  +  PK +LP  L  Y+ Y GSLTTPP  ++V W VL    ++SE Q+  FR L+F   E     ++ NNFRP  P+
Sbjct:   15 FPGPSAWSK-DYPIAEGPRQSPINIVPDEAVY--DANLPPISLNYDNCTSINISNNGHSVVVEFDDADDRSVIQGGPLNNAYRLKQFHFHWGGKGCHGSEHTVSGKTYTSELHLVHWNAARYGSFGEAVAASDGLAVLGVFLEIGDEHRGLHKITDALYM-VKFKGTVADFRDFNPKCLLPRSL-GYWTYPGSLTTPPLYESVTWIVLAEPIEVSEKQMGKFRTLLFSGEEEEVRKRMENNFRPPQPL 257          
BLAST of Carbonic anhydrase vs. Ensembl Sea Lamprey
Match: CA2 (carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373])

HSP 1 Score: 137.117 bits (344), Expect = 9.768e-38
Identity = 90/257 (35.02%), Postives = 130/257 (50.58%), Query Frame = 2
Query:  299 GPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKH-FASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            GP  W +       G RQSPIDI P   +Y   L    +S   +   S++   H F+  Y +  D+  +  GG      K    H+HWG+S+  GSEH + G  +  E HLV ++   Y+SF +A    +GL V+G F +VG NN  +  V  A+ + +  K    +     P  +LP  L +++ Y GSLTTPP  ++ IW VL+     S++QL+ FR+L   D    KLV NFRP  P++       RVV ASF
Sbjct:   16 GPEVWGKH-FKNADGSRQSPIDIEPASAVYEAALGALSVSYSGADAKSISNSGHSFSVDYDDSGDSSAVLSGGPLANPYKLKQFHFHWGASDAKGSEHTVDGKSYSAELHLVHWNAAKYASFDEAKDKSDGLAVLGAFVKVGANNAGLQKVTDALNA-IADKGAKADFKNYDPSVLLPKSL-DFWSYLGSLTTPPLNESAIWIVLKDPISASKEQLAAFRSLKASDGS--KLVCNFRPTQPLKG------RVVQASF 261          
BLAST of Carbonic anhydrase vs. Ensembl Sea Lamprey
Match: ca4b (carbonic anhydrase IV b [Source:ZFIN;Acc:ZDB-GENE-080815-5])

HSP 1 Score: 116.316 bits (290), Expect = 1.506e-29
Identity = 90/282 (31.91%), Postives = 141/282 (50.00%), Query Frame = 2
Query:  251 ESSSDNWGYKEGQS----FKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVT--IEKHFASIYLNFNDNWKITFGG-NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKS-HMKLKTFSVNVSEIPPKDILP--LELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFG---DPEFGKLVNNFRPIFPIEKSTDYILRVVYAS 1057
            E S+ +W Y    S     +GP  W++  +  C G  QSPIDI          L+       +S    VT  I+ +  ++ ++      ++ GG  G    V +H+HWG+ +  GSEH + G +FP+E H+V Y+   Y +F  A    +GL V+GF Y VG  N     + +A+ S   ++ T +V +  +   ++LP  + +  YYRY GSLTTP C + V WTV      + E+Q+  F ++ F    DP+   +VNNFRP+  +        R+VYAS
Sbjct:   17 EYSTAHWCYDSQDSECAFCEGPRTWYK-NSPACSGTSQSPIDIHTGSVKRNATLQKLKFIGYDSTPAGVTWSIQNNGHTVQVDLQGEIAVSGGGLPGTFNAVQMHFHWGNPHGPGSEHTINGKQFPVELHIVHYNTK-YLTFDGAKNEKDGLAVLGFLYAVGPTNNNYNTIINALPSVANQVTTRTVYMFNL--DNLLPSYVNMSKYYRYSGSLTTPGCGEVVTWTVFEEPIIMDENQIKKFSSVFFSTKEDPQQILMVNNFRPVQKLNS------RIVYAS 288          
BLAST of Carbonic anhydrase vs. Ensembl Sea Lamprey
Match: ca8 (carbonic anhydrase VIII [Source:ZFIN;Acc:ZDB-GENE-050417-26])

HSP 1 Score: 100.523 bits (249), Expect = 1.716e-24
Identity = 80/266 (30.08%), Postives = 124/266 (46.62%), Query Frame = 2
Query:  314 WQLPNTTCGGQRQSPIDIVPKFTIYWEDL-KLPI-ISRINSINHSVTIEKHFASIYLNFNDNWKITFGG----NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVG---LNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELM-NYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNL-------VFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            W L      G+ QSPI+I  +   +   L   P+ +S +      V  + H   I++    +  +T GG        +   + +HWG  +  GSEH +    FPME HL+ ++  LY + + A    NG+ +I  F ++G   L    +T +   I+   K KT    +  + P  +LP  L+ +Y+ YEGSLTTPPC +NV+W + R    +S  Q+  FR L          D   G+L +NFRP   +        RV+ ASF
Sbjct:    5 WGLLFPDANGENQSPININSREATFDPSLLTAPLCLSYLTCRECEVLNDGHSLHIHIR---SKSVTTGGPFPIGQEFELSHICFHWGKEDQRGSEHTVNFKAFPMECHLIHWNATLYKNIEDAMGKENGIAIIALFVQIGREHLGLKGLTDILQEIQYKGKAKT----IPSLNPNTLLPDPLLRDYWVYEGSLTTPPCCENVLWLLFRYPLTLSHAQIEEFRRLRTHSKGVAPSDGCDGQLGDNFRPTQQLND------RVIRASF 257          
BLAST of Carbonic anhydrase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006943.1 (pep scaffold:Pmarinus_7.0:GL476401:102791:181294:1 gene:ENSPMAG00000006261.1 transcript:ENSPMAT00000006943.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 96.6709 bits (239), Expect = 1.388e-21
Identity = 72/253 (28.46%), Postives = 117/253 (46.25%), Query Frame = 2
Query:  335 CGGQRQSPIDIV---------PKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG-NGCLKPVAVHWHWGSSNYI-GSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGL-NNPAITMVASAIKSHMKLKTFSVNVSEIP--PKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQL-SVFRNLVFGDPEFGKLV----NNFRPIFPIEKSTDYI 1036
            C G+RQSPIDI          P   + +E   +P        + + TI+    ++ ++ + ++ +  GG  G  +   + +HWG SN   GSEHRL G  FP+E  +  Y    +SSF  A  +   +  +   + +   NN A   +  A+K   ++    ++V   P    D+LP     ++RY G+ TTPPC Q V WTV      IS  QL +++  L+     +  L+    +NFRP  P+    D +
Sbjct:    8 CRGERQSPIDIASEVQAEVLSPADGLEFEGWDVP--------STTTTIKHDGKTVIVHLSGDYHLRGGGLQGRYRMAWLTFHWGHSNGTEGSEHRLSGRSFPLEVQIYGYSQEHHSSFAAAMKAGGNMAALSILFEIAKDNNSAYIPLLEAVK---RVCQPGIHVHATPFCASDLLPESTDEFFRYSGTTTTPPCAQGVEWTVFPRTVHISAHQLEALYGVLIMVRAGYAMLLEYLQDNFRPPQPLPSGADLV 249          
BLAST of Carbonic anhydrase vs. Ensembl Sea Lamprey
Match: ca5a (carbonic anhydrase Va [Source:ZFIN;Acc:ZDB-GENE-080220-57])

HSP 1 Score: 75.485 bits (184), Expect = 9.726e-16
Identity = 70/243 (28.81%), Postives = 110/243 (45.27%), Query Frame = 2
Query:  314 WQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDN------WKITFGGNGCLKPVAVHWHWGSSNYI-GSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF--GDPEFGKLVNNFRPIFPI 1015
            W   ++T  G+RQSPIDI P   ++  D  L  +      +  + +  +  S    + DN      W  T  G   +  + +H    S +YI  +EH    +    + HLV +      SF +A VS  GL V+G F  VG  +  +  +  A+ + +  K     V    P  +LP   ++++ Y GSLTTPP  + V W +L+    IS +QL+ FR L          ++V+NFR   PI
Sbjct:    3 WDTKHSTISGRRQSPIDIQPAEGMF--DSGLGPLHTHYHRSGPMLLYNNGYSFLAEYPDNCSANGTWVGTRAGTTVIISIRLH---HSLDYITKNEHTNSMSYLCPQLHLVHWHESC-ESFNEALVSKKGLAVLGVFVEVGETHARLQELVEALPN-ITHKGMMHEVGTFDPSGLLP-PCLDFWTYPGSLTTPPPYETVTWFILKRSMSISGEQLASFRRLYVSAAGERAVRMVDNFRMPQPI 237          
BLAST of Carbonic anhydrase vs. Ensembl Nematostella
Match: EDO46081 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR00])

HSP 1 Score: 118.242 bits (295), Expect = 1.896e-30
Identity = 84/264 (31.82%), Postives = 126/264 (47.73%), Query Frame = 2
Query:  266 NWGYKEGQSFKGPSQWWQLPN--TTCGGQRQSPIDIVPKFTIYWE-----DLKLPIISRINSINH-------SVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIG-FFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGK---LVNNFRP 1003
            +W Y E     GPS W   PN    CGG+ QSPI+I  +   Y       D+K P  + +  +NH        +   + F +   + +  +++             H+H GSS+  GSEH + G ++P+E HLV Y+   Y +   A    +GL VI   F     +NPA+  +   +++    K   + V  +P   I+P +   +YRY GSLTTPPC + V W VL+    ISE QL  FR++     +  K   LV+NFRP
Sbjct:    3 DWSYDEA---TGPSTW---PNHFPHCGGKMQSPININTEEAKYDGSLTDLDIKYPNTTDVLLVNHHGHAIEADILSSEPFVATGADLSSRYRL----------AQFHFHVGSSDIQGSEHHIHGVKYPLEMHLVHYN-DKYPNASSAQGLLDGLAVISVLFESSSTDNPALNEIIDNLQN-ASYKDEEITVQNVPVGKIIPTDTEKFYRYNGSLTTPPCFETVKWIVLKKTASISEKQLRQFRSVFSTSRQATKPNSLVDNFRP 248          
BLAST of Carbonic anhydrase vs. Ensembl Nematostella
Match: EDO35860 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKA8])

HSP 1 Score: 112.849 bits (281), Expect = 9.275e-29
Identity = 79/249 (31.73%), Postives = 117/249 (46.99%), Query Frame = 2
Query:  299 GPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDL---------KLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCL-KPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPI 1015
            GPS+W     + C G  QSPIDI+     + + L          +P  S+I+  N+      H   + +     + ++ GG G     V  H HWGS N  GSEH + G  F    H+VSY+   Y +   A    +GL V+G   +VG  + A+      I S  K+ T           D+LP    N+YRY+GSLTTP C ++V W+V+ +   +SE QL++ R L   D     + +NFR   P+
Sbjct:    1 GPSKWSS-SFSQCNGSSQSPIDIITSSVAFDQSLGELQFVNFDTIPTGSKISLKNNG-----HAFQVNMLSAGTFTVSGGGLGATYSTVQFHLHWGSKNEQGSEHLIDGKAFAGAIHIVSYNT-KYPNISAAVDKSDGLAVVGILLKVGTESAALKKFMENIGSVTKVNTSDEFAQPAKLGDLLPSN-KNFYRYQGSLTTPGCQESVTWSVMANPITVSEAQLAILRGLKQKDG-VAVIQDNFRNTMPL 240          
BLAST of Carbonic anhydrase vs. Ensembl Nematostella
Match: EDO45955 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRH8])

HSP 1 Score: 101.293 bits (251), Expect = 1.680e-24
Identity = 74/248 (29.84%), Postives = 116/248 (46.77%), Query Frame = 2
Query:  299 GPSQWW-QLPNTTCGGQRQSPIDIVPKFTIYWEDL---------KLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGC-LKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIF 1009
            GP  W  + P   C G  QSPI+IV    +Y   L         ++P  ++I   N+    + +F +  L     + +  GG G        H H G  +  G+EH + G R     H+V+Y+   Y     A+   +GL VIG    VG  N  +  V   +++  K+   S    E     +LP    +++RY+GSLTTPPC ++V WTV+++   IS DQL   R+++  D    K+ +N+R I 
Sbjct:    1 GPDHWANRYP--ACNGSSQSPINIVTSSVMYDSSLGKLQFNNFDRIPSGAKIMVRNNGHAFQVNFMTPNL-----FYVHGGGLGANFTTAQFHMHLGEDDTRGAEHLIDGQRNAACIHIVNYNTK-YPDISTAANKSDGLAVIGVILEVGAENAGLAKVLKYVENVTKVGNVSDLAQEFSLGSLLPSN-TDFFRYKGSLTTPPCYESVTWTVMKTKTTISHDQLMKLRSIMEKDG-VHKITDNYRHIL 238          
BLAST of Carbonic anhydrase vs. Ensembl Nematostella
Match: EDO40438 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S762])

HSP 1 Score: 88.1965 bits (217), Expect = 7.325e-20
Identity = 67/230 (29.13%), Postives = 107/230 (46.52%), Query Frame = 2
Query:  350 QSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNY-IGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLN-NPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKST 1027
            QSPIDIV K     +D  L  +        + T+     ++ L F +N  +  GG      +   + +HW ++    GSEH +      +E  LV ++   Y +  +A     G+ ++  F++VG   N  + ++   +          V  + I PK   P E   Y+ YEGSLTTPP T+NV W + +S   +SEDQ++VFRN+     +   +  N RP+ PI   T
Sbjct:   17 QSPIDIVTKDVT--QDSSLGSLWNTYEPVANSTLTNDGRTLQLTFANNNNVLSGGPLTDEYQLAMIKFHWAATEESAGSEHMIDSQGHAIEVQLVHWNKTKYRNIGEAITGEQGICILAVFFQVGNEANEGLDVIVDLLSK----DEHKVVKAAIDPKIFFPAE-SEYWTYEGSLTTPPLTENVTWVICQSSLILSEDQMNVFRNIRNSHGDI--MAKNSRPVCPINGRT 237          
BLAST of Carbonic anhydrase vs. Ensembl Nematostella
Match: EDO42126 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2D8])

HSP 1 Score: 85.1149 bits (209), Expect = 6.003e-19
Identity = 81/266 (30.45%), Postives = 117/266 (43.98%), Query Frame = 2
Query:  302 PSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIIS---------RINSINHSVTIE-KHFASIYLNFNDNWKITFGG-NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPN--GLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            P +W         G+RQSPIDIV   T +  D  +P +          ++ +  HSV+   +  AS+         IT G  +   K    H+HWG     GSEHR+ G  +P E H+V Y+  LY     A  S N  GL V+G F  V  +   + +    I  H+    FS               ++  + Y GSLTTPP ++ V W VL++  +IS  QL +F  L     E   + +N+RP  P+        RVV A+F
Sbjct:    2 PGKWSVKFPIAASGKRQSPIDIVSNETKF--DSTIPPVKVHYDPFTKGKLTNTGHSVSFSGESDASV-----PTPDITSGPLSHKYKFAQFHFHWGKDEKEGSEHRVDGKMYPSEMHIVHYNSDLYKDAASAMSSDNKDGLCVLGVFLEVKEDAFLLNICTCTI--HL---FFSC--------------VLECWTYPGSLTTPPLSEIVNWIVLKNTIEISHHQLKLFHGLQNAKGEC--ITHNYRPPCPLHG------RVVKATF 233          
BLAST of Carbonic anhydrase vs. Ensembl Medaka
Match: ca5a (carbonic anhydrase 5A [Source:NCBI gene;Acc:101173143])

HSP 1 Score: 141.739 bits (356), Expect = 3.386e-38
Identity = 89/245 (36.33%), Postives = 132/245 (53.88%), Query Frame = 2
Query:  314 WQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKP----VAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFG---KLVNNFRPIFPIEKST 1027
            WQ P    GG RQSPIDIV + +I+  +LK P+++  +  +    I  +  S  + ++D    +    G LK        H+HWG +N  GSEH L    FP E HLV ++   YS F++A +  NGL VIG F +VG  +  +  +  A+ + ++ K   V  +   P  +LP    NY+ Y GSLTTPP T++V W ++R   ++S DQL+VFR+L+F   E      +VNNFR   P+   T
Sbjct:   52 WQGPLAVPGGDRQSPIDIVVRKSIFDGELK-PLVTSYDP-HTCQQIWNNGYSFLVEYDDTTDKSTLKGGPLKDKFRLCQFHFHWGETNAWGSEHTLDRKLFPAELHLVHWNSDKYSLFEEAVMEDNGLAVIGVFLKVGKRHEGLQKLVDALPA-IRHKDSVVEFNRFDPACLLPTNTDNYWTYHGSLTTPPLTESVTWIIMRQHIEVSHDQLAVFRSLLFTSAEEEVQRSMVNNFRVQQPLRGRT 293          
BLAST of Carbonic anhydrase vs. Ensembl Medaka
Match: cahz (carbonic anhydrase [Source:NCBI gene;Acc:101161087])

HSP 1 Score: 134.806 bits (338), Expect = 3.055e-36
Identity = 92/254 (36.22%), Postives = 139/254 (54.72%), Query Frame = 2
Query:  260 SDNWGYKEGQSFKGPSQWWQ-LPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEK--HFASIYLNFNDNWKITFGG-NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF-GDPE-FGKLVNNFRP 1003
            S  WGY       GP  W +  P     G RQSPI+IVPK   +   LK P+  R ++ +    +     F   +++  D+  +T G  +G  +    H+HWG+S+  GSEH + G  FP E HLV ++   Y+SF +A+  P+GL V+G F ++G  NP +  V  A+ + +K K      +   PK +LP  L +Y+ Y+GSLTTPP  ++V W VL+    +S  Q++ FR+L+F GD E    +V+NFRP
Sbjct:    2 SHAWGYGPSD---GPETWAENFP--LASGPRQSPINIVPKEAQFDPSLK-PLKIRYDARDAKGILNNGHSFQVDFVDDTDSSTLTGGPISGTYRLKQFHFHWGASDERGSEHTINGITFPCELHLVHWNTK-YASFGEAADKPDGLAVVGVFLKIGAANPKLQKVLDALDA-IKTKGKQNVFANFDPKTLLPGSL-DYWTYDGSLTTPPLLESVTWIVLKEQISVSPAQMAKFRSLLFTGDGEPLCNMVDNFRP 246          
BLAST of Carbonic anhydrase vs. Ensembl Medaka
Match: ca7 (carbonic anhydrase 7 [Source:NCBI gene;Acc:101170576])

HSP 1 Score: 129.798 bits (325), Expect = 2.517e-34
Identity = 86/259 (33.20%), Postives = 133/259 (51.35%), Query Frame = 2
Query:  257 SSDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGG--NGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFG---KLVNNFRPIFPIE 1018
            +  +WGY EG    GPS W +       G RQSPIDI+P   +    L   +++  +  + +++   H   +  + +D+  +  GG  +   +    H+HWG     GSEH + G  +  E HLV ++   Y SF +AS +P+GL V+G F   G ++  + M+  A+   +K K          PK +LP  L +Y+ Y GSLTTPP  ++VIW VL+    +SE QL  FR L+F   E     ++ NNFRP  P++
Sbjct:    2 TGHHWGYGEGD---GPSAWHK-NYPVAQGSRQSPIDIIPHQALQDRSLGPIVLNYDHCTSINISNNGHSVVVEFDDSDDRSVIQGGPLDNPYRLKQFHFHWGGKGCEGSEHTVDGYGYASELHLVHWNAVKYCSFGEASTAPDGLAVLGIFLETGDDHRWLHMITDALYM-VKFKGSGTEFKGFNPKCLLPSSL-HYWTYLGSLTTPPLHESVIWIVLKEPIAVSEKQLGKFRLLLFTGEEEDQRTRMENNFRPPQPLK 254          
BLAST of Carbonic anhydrase vs. Ensembl Medaka
Match: ENSORLT00000031470.1 (carbonic anhydrase 1 [Source:NCBI gene;Acc:101168081])

HSP 1 Score: 125.561 bits (314), Expect = 7.960e-33
Identity = 93/275 (33.82%), Postives = 145/275 (52.73%), Query Frame = 2
Query:  260 SDNWGYKEGQSFKGPSQWWQ-LPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPV----AVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVF---GDPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            S +WGY       GP +W +  P     G RQSPIDIVP    Y   LK P+  + +  +  + I  +  SI + F D+   +   NG +  V      H+HWG ++  GSEH + GT++  E HLV ++   Y++F +A+  P+GL V+G F +VG  NP +  +  A    +K K    + +   P  +LP   ++Y+ Y+GSLTTPP  ++V W V +    +S  Q++ FR+L+F   G+ E   +V+N+RP  P++       R V ASF
Sbjct:    2 SHSWGYAP---TNGPDKWGKNFP--IADGVRQSPIDIVPAAASYDGGLK-PLCLKYDP-STCLEILNNGHSIQVTFIDDSDKSTLTNGPISGVYRLKQFHFHWGGADDRGSEHTVNGTKYAAELHLVHWNT-KYANFGEAASKPDGLAVVGVFLKVGDANPNLQKLLDAFNG-IKTKGSQTSFAGFDPATLLP-GCLDYWTYDGSLTTPPLLESVTWIVCKEPISVSPGQMAKFRSLLFSAQGEAEC-CMVDNYRPPQPLKG------RRVRASF 259          
BLAST of Carbonic anhydrase vs. Ensembl Medaka
Match: ca6 (carbonic anhydrase 6 [Source:NCBI gene;Acc:101155193])

HSP 1 Score: 117.857 bits (294), Expect = 2.776e-28
Identity = 81/269 (30.11%), Postives = 134/269 (49.81%), Query Frame = 2
Query:  266 NWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNY--IGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVG--LNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            +W Y EG   +   Q W      C G++QSPIDI  +   +  ++    +S  ++      +  +  ++ +N      I+ G  G    V +H HWG S+    G+EH + G R+  E H+V Y+   Y SF +A    +GL V+ F Y  G   N      +A+  K  +K    S+N++ I  + +LP  L +++RYEGSLTTPPC +++IWTV  +   +S++Q+    + +  D +   L N++R   P+        RVV +SF
Sbjct:   23 HWTYTEGALDQ---QHWATEYPACAGKKQSPIDIQRRNVKHNPNMLQLELSNYDAQQGKFLMTNNGHTVQINLPPTMTISQGLPGIYTAVQMHLHWGGSHQEASGAEHTIDGVRYMAELHIVHYNSEKYRSFSEAKDKKDGLAVLAFVYDDGHFENTYYSDFIANLEK--IKYAGQSMNITSIDVRSMLPENLNHFFRYEGSLTTPPCFESIIWTVFDTPITLSQNQIRRLESTLM-DIDNKTLWNDYRIAQPLND------RVVESSF 279          
BLAST of Carbonic anhydrase vs. Planmine SMEST
Match: SMESG000017178.1 (SMESG000017178.1)

HSP 1 Score: 670.233 bits (1728), Expect = 0.000e+0
Identity = 324/324 (100.00%), Postives = 324/324 (100.00%), Query Frame = 2
Query:  176 MRIILCFGIIIASFVIRSDSVLDVHESSSDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFNYSSKLMTNFVLPAFILLLTPFFNNYLRK 1147
            MRIILCFGIIIASFVIRSDSVLDVHESSSDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFNYSSKLMTNFVLPAFILLLTPFFNNYLRK
Sbjct:    1 MRIILCFGIIIASFVIRSDSVLDVHESSSDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFNYSSKLMTNFVLPAFILLLTPFFNNYLRK 324          
BLAST of Carbonic anhydrase vs. Planmine SMEST
Match: SMESG000017182.1 (SMESG000017182.1)

HSP 1 Score: 275.018 bits (702), Expect = 1.936e-89
Identity = 136/301 (45.18%), Postives = 192/301 (63.79%), Query Frame = 2
Query:  188 LCFGIIIASFVIRSDSVLDVHESSSDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMV-ASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFNYSSKLMTN 1087
            L FG++I +F  RS       E+  + WGYK G+SFK PSQW  +  ++CGG+RQSPIDI  + T YW  L    +  I+S+N+  T+ K   ++ L+  + W+I+FG  GCL P  +HWHWGS +  GSEH +   ++P+EGHLVSYDC +Y+S+Q A   P+GLHVIGFFY +G N+  I +V  S + +   LK  SV++ E+     LP  L  Y+RYEGSLTTP C +NVIWTVL     + +DQL   R L +  PE G +V+N+RP+  + ++ DY+ R+VY+SFN S  L +N
Sbjct:   10 LVFGLLIFAF-DRS------READPNEWGYKTGKSFKDPSQWKTIKGSSCGGRRQSPIDIQTEATQYWPALSPIKLENISSLNNQSTVVKDPLALKLDLVEKWRISFGNEGCLTPFTIHWHWGSDDSQGSEHTVNNKKYPLEGHLVSYDCNIYNSYQNALSGPSGLHVIGFFYEIGSNDSTIDLVLKSQLLAPRPLK--SVSIPELNLTSFLPKNLEKYFRYEGSLTTPDCVENVIWTVLNEKLSVGKDQLRKLRTLKYDFPESGDMVDNYRPVVKLTENGDYVKRIVYSSFNISPGLKSN 301          
BLAST of Carbonic anhydrase vs. Planmine SMEST
Match: SMESG000017171.1 (SMESG000017171.1)

HSP 1 Score: 258.07 bits (658), Expect = 3.276e-83
Identity = 133/274 (48.54%), Postives = 171/274 (62.41%), Query Frame = 2
Query:  254 SSSDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIK-SHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFNYSS 1072
            S + NWGY      KGPS W  + N TC G RQSPIDIV + ++Y +DL+   I +I++ N   T+E+H  SIYL  N++W ITFGGN CL+P ++HWHWGS   +GSEH L G  +P+EGHLVSY+C  YSS  +A  SP GL+VIG FY++G  N  I  +  A++         SV ++EI  ++ILP  L  YY+Y+GSLTTPPCT+NV WTVL     I E QL VFR   F  P  GK+ NNFRPI     S     R +Y+SF   S
Sbjct:   23 SGTGNWGYTSTSDIKGPSDWKDI-NPTCDGARQSPIDIVTRSSLYLKDLQRIEIKKIDNFNKFSTLERHETSIYLKLNNSWGITFGGNQCLRPDSIHWHWGSKGALGSEHSLDGKHYPIEGHLVSYNCMKYSSLNEAKSSPEGLYVIGIFYKIGPKNVLIDKIIPAMQSLISSSDISSVIINEISVEEILPKNLDKYYQYDGSLTTPPCTENVRWTVLNEELTIDESQLEVFRQFDFESPNSGKMENNFRPIL----SKFNEKRTIYSSFKTGS 291          
BLAST of Carbonic anhydrase vs. Planmine SMEST
Match: SMESG000016838.1 (SMESG000016838.1)

HSP 1 Score: 228.024 bits (580), Expect = 2.674e-71
Identity = 116/267 (43.45%), Postives = 165/267 (61.80%), Query Frame = 2
Query:  260 SDNWGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASF 1060
            +D WGYK  +  K PS W  L   TCGG  QSP++I      Y ++LK  +I +   I     +EK   S+YL+FN  W IT G + C+KPV++HWHWGS N  G+EH +    +P+EGH+VSY+C LY+S + A  +PNGL+VIGFFY++G  N A+  + S I   +  K   VNV+E+    I+P  +  YY Y+GSLTTPPC +NV W +++    +S  QL++FR L F  P  G +++NFRP+F  + +     RV+YASF
Sbjct:   23 TDVWGYKASRGIKDPSGWKDL-FPTCGGSYQSPLNIQTNQVKYSQNLKPILIRKGVPIRSLKPLEKLARSLYLSFNGYWLITLGTDKCMKPVSIHWHWGSVNKQGAEHTINNYSYPVEGHIVSYNCELYNSMKAAESAPNGLYVIGFFYKLGKKNAALEKIFSGIGPILAKKESIVNVTEVGIDLIIPNNIEKYYVYDGSLTTPPCIENVKWIIIKDELTLSSYQLNIFRELEFESPLTGPMLDNFRPVFQNKNN-----RVIYASF 283          
BLAST of Carbonic anhydrase vs. Planmine SMEST
Match: SMESG000072395.1 (SMESG000072395.1)

HSP 1 Score: 133.65 bits (335), Expect = 6.088e-36
Identity = 86/262 (32.82%), Postives = 121/262 (46.18%), Query Frame = 2
Query:  269 WGYKEGQSFKGPSQWWQLPNTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIYLNFNDNWKITFGGNGCLK--PVAV---------HWHWGSSNYIGSEHRLQGTRFPMEGHLVSYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKS--HMKLKTFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDISEDQLSVFRNLVFGDPEFGKLVNNFRPIFPI 1015
            WGY    +  GP   W     + GG RQSPI+I        + LK  I   I  +  +   E+  +   +    N++I   G  C+   PV            +HWGS++Y GSEH + G +FP E H V Y+   Y  F++A   P+GL ++     +G  N  I  +   + S    +   F    S +   +ILP  L  YY Y GSLTTPPC ++V W +      I  DQL +FR +  GD   G   +NFRPI PI
Sbjct:    4 WGYG---ADDGP-HTWHASFPSAGGCRQSPINI------ELDKLKYDITLNIRPLAVAFEPERQLSQTLVYTGHNFRIDVAGGSCVSGGPVPTGQTCILSHFSFHWGSTDYSGSEHLINGHQFPGELHFVCYNASKYRCFEEAMGQPDGLLIVAVLLHIGSKNTTIERLVGPLTSIQFFRQHDFRQETSLLDLTEILPRNLCRYYTYPGSLTTPPCYESVTWLLFEETVGIDSDQLCMFRKIHMGDSCCGP--DNFRPICPI 253          
The following BLAST results are available for this feature:
BLAST of Carbonic anhydrase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CA76.121e-4236.80carbonic anhydrase 7 [Source:HGNC Symbol;Acc:HGNC:... [more]
CA71.059e-3437.44carbonic anhydrase 7 [Source:HGNC Symbol;Acc:HGNC:... [more]
CA28.296e-3332.12carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:... [more]
CA13.050e-3132.36carbonic anhydrase 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
CA13.050e-3132.36carbonic anhydrase 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
back to top
BLAST of Carbonic anhydrase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cah-54.031e-2731.84Putative carbonic anhydrase 5 [Source:UniProtKB/S... [more]
cah-32.910e-2231.78Putative carbonic anhydrase 3 [Source:UniProtKB/S... [more]
cah-18.779e-2026.16Putative carbonic anhydrase-like protein 1 [Sourc... [more]
cah-41.647e-1630.09Carbonic AnHydrase [Source:UniProtKB/TrEMBL;Acc:Q... [more]
cah-22.229e-1625.00Putative carbonic anhydrase-like protein 2 [Sourc... [more]
back to top
BLAST of Carbonic anhydrase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CAH14.221e-3532.96gene:FBgn0027844 transcript:FBtr0080539[more]
CAH24.997e-2729.76gene:FBgn0027843 transcript:FBtr0076001[more]
CAH91.782e-2230.29gene:FBgn0039486 transcript:FBtr0085133[more]
CAH21.843e-2235.15gene:FBgn0027843 transcript:FBtr0333381[more]
CAH46.472e-2028.81gene:FBgn0039235 transcript:FBtr0084732[more]
back to top
BLAST of Carbonic anhydrase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cahz5.345e-3835.19carbonic anhydrase [Source:NCBI gene;Acc:30331][more]
ca23.780e-3635.53carbonic anhydrase II [Source:ZFIN;Acc:ZDB-GENE-03... [more]
ca78.212e-3634.55carbonic anhydrase VII [Source:ZFIN;Acc:ZDB-GENE-0... [more]
ca4b3.822e-3333.33carbonic anhydrase IV b [Source:ZFIN;Acc:ZDB-GENE-... [more]
ca4a6.940e-3334.43carbonic anhydrase IV a [Source:NCBI gene;Acc:5551... [more]
back to top
BLAST of Carbonic anhydrase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
proca19.447e-3636.10protein interacting with cyclin A1 [Source:Xenbase... [more]
proca11.169e-3335.71protein interacting with cyclin A1 [Source:Xenbase... [more]
ca138.860e-3333.45carbonic anhydrase XIII [Source:NCBI gene;Acc:7799... [more]
ca5b2.074e-3132.93carbonic anhydrase VB, mitochondrial [Source:NCBI ... [more]
ca5b3.242e-3132.93carbonic anhydrase VB, mitochondrial [Source:NCBI ... [more]
back to top
BLAST of Carbonic anhydrase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Car72.476e-4136.06carbonic anhydrase 7 [Source:MGI Symbol;Acc:MGI:10... [more]
Car72.868e-3536.79carbonic anhydrase 7 [Source:MGI Symbol;Acc:MGI:10... [more]
Car72.868e-3536.79carbonic anhydrase 7 [Source:MGI Symbol;Acc:MGI:10... [more]
Car121.604e-3232.51carbonic anhydrase 12 [Source:MGI Symbol;Acc:MGI:1... [more]
Car128.558e-3232.45carbonic anhydrase 12 [Source:MGI Symbol;Acc:MGI:1... [more]
back to top
BLAST of Carbonic anhydrase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P43166|CAH7_HUMAN2.940e-4136.80Carbonic anhydrase 7 OS=Homo sapiens OX=9606 GN=CA... [more]
sp|Q9ERQ8|CAH7_MOUSE1.732e-4036.06Carbonic anhydrase 7 OS=Mus musculus OX=10090 GN=C... [more]
sp|Q92051|CAHZ_DANRE4.035e-3735.19Carbonic anhydrase OS=Danio rerio OX=7955 GN=cahz ... [more]
sp|Q8UWA5|CAH2_TRIHK8.615e-3433.82Carbonic anhydrase 2 OS=Tribolodon hakonensis OX=1... [more]
sp|P83299|CAH1_CHIHA2.140e-3334.07Carbonic anhydrase 1 OS=Chionodraco hamatus OX=361... [more]
back to top
BLAST of Carbonic anhydrase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A452QQI41.170e-4137.22Carbonic anhydrase 7 OS=Ursus americanus OX=9643 G... [more]
U6D7N11.588e-4138.43Carbonic anhydrase 7 (Fragment) OS=Neovison vison ... [more]
M3WHK21.668e-4138.29Carbonic anhydrase 7 OS=Felis catus OX=9685 GN=CA7... [more]
A0A2U3VFI91.795e-4138.06carbonic anhydrase 7 OS=Odobenus rosmarus divergen... [more]
A0A2Y9IBR82.788e-4137.31carbonic anhydrase 7 OS=Neomonachus schauinslandi ... [more]
back to top
BLAST of Carbonic anhydrase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cahz2.900e-3937.21carbonic anhydrase-like [Source:NCBI gene;Acc:1030... [more]
ca78.565e-3534.77carbonic anhydrase 7 [Source:NCBI gene;Acc:1030418... [more]
ca5a2.807e-3432.16carbonic anhydrase 5B, mitochondrial [Source:NCBI ... [more]
ca5a6.394e-3432.65carbonic anhydrase 5B, mitochondrial [Source:NCBI ... [more]
ca77.047e-3434.68carbonic anhydrase 7 [Source:NCBI gene;Acc:1030418... [more]
back to top
BLAST of Carbonic anhydrase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CA29.768e-3835.02carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:... [more]
ca4b1.506e-2931.91carbonic anhydrase IV b [Source:ZFIN;Acc:ZDB-GENE-... [more]
ca81.716e-2430.08carbonic anhydrase VIII [Source:ZFIN;Acc:ZDB-GENE-... [more]
ENSPMAT00000006943.11.388e-2128.46pep scaffold:Pmarinus_7.0:GL476401:102791:181294:1... [more]
ca5a9.726e-1628.81carbonic anhydrase Va [Source:ZFIN;Acc:ZDB-GENE-08... [more]
back to top
BLAST of Carbonic anhydrase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Carbonic anhydrase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO460811.896e-3031.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO358609.275e-2931.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459551.680e-2429.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO404387.325e-2029.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO421266.003e-1930.45Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Carbonic anhydrase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ca5a3.386e-3836.33carbonic anhydrase 5A [Source:NCBI gene;Acc:101173... [more]
cahz3.055e-3636.22carbonic anhydrase [Source:NCBI gene;Acc:101161087... [more]
ca72.517e-3433.20carbonic anhydrase 7 [Source:NCBI gene;Acc:1011705... [more]
ENSORLT00000031470.17.960e-3333.82carbonic anhydrase 1 [Source:NCBI gene;Acc:1011680... [more]
ca62.776e-2830.11carbonic anhydrase 6 [Source:NCBI gene;Acc:1011551... [more]
back to top
BLAST of Carbonic anhydrase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000017178.10.000e+0100.00SMESG000017178.1[more]
SMESG000017182.11.936e-8945.18SMESG000017182.1[more]
SMESG000017171.13.276e-8348.54SMESG000017171.1[more]
SMESG000016838.12.674e-7143.45SMESG000016838.1[more]
SMESG000072395.16.088e-3632.82SMESG000072395.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023854 ID=SMED30023854|Name=Carbonic anhydrase|organism=Schmidtea mediterranea sexual|type=transcript|length=1335bp
GTCCAATAAACTGATAACATATGGTACAAATGTGCCTCGAGGTGTTGTGC
AAATATACAAGCACATTTTCATCCAATCAAATCGATAATTAAAACAAATT
AAATAATATATACGCACAAAATTACTTGCTTATTATCGGTATCTCATTTT
AGTTTTTAATATATCGAAATTACTCATGAGAATAATTTTGTGTTTTGGAA
TAATAATTGCCAGTTTCGTGATCCGATCGGATTCGGTGCTGGACGTCCAC
GAGTCCTCCTCGGACAACTGGGGCTACAAAGAAGGCCAATCGTTCAAGGG
TCCCTCTCAATGGTGGCAGTTGCCAAATACAACATGTGGAGGCCAAAGAC
AGTCTCCAATCGACATCGTGCCGAAGTTCACAATATATTGGGAGGATTTG
AAGTTGCCCATCATTTCCCGAATAAACTCCATCAATCATTCTGTAACAAT
TGAAAAACATTTTGCCTCAATTTACCTCAATTTCAATGACAATTGGAAAA
TAACCTTCGGTGGAAACGGATGCTTGAAACCGGTTGCAGTCCACTGGCAT
TGGGGGTCAAGTAACTATATTGGATCGGAACATAGACTGCAGGGTACCCG
GTTCCCGATGGAAGGCCATTTAGTAAGCTATGATTGCGGCCTTTACTCTT
CCTTTCAGCAAGCATCCGTCTCACCAAATGGCCTCCATGTAATTGGCTTC
TTTTACCGGGTCGGGTTAAATAACCCTGCAATAACTATGGTAGCTAGCGC
CATTAAATCACACATGAAATTGAAAACGTTCTCTGTCAATGTCTCAGAAA
TTCCTCCTAAAGATATTTTGCCACTAGAACTGATGAACTATTATAGATAT
GAGGGCTCCCTTACCACCCCGCCATGTACTCAGAATGTGATTTGGACGGT
GCTGCGATCTGTGCAAGATATCAGCGAAGATCAATTGTCTGTTTTCCGAA
ATTTAGTCTTCGGAGATCCCGAATTTGGAAAGTTGGTAAACAATTTTCGG
CCGATTTTTCCAATCGAAAAGTCAACGGATTATATTCTCCGTGTCGTCTA
CGCATCCTTTAATTACAGTTCGAAACTCATGACCAATTTTGTGTTACCTG
CGTTTATTTTATTACTCACGCCTTTTTTCAACAATTATTTACGGAAGTAA
AGTCCCGTACAGACGGACTAGGACAGTACAGAGTGTAGTTTTTGTCTCTT
GGATGAAGTCAAGTTCAGAAATATTAATCATAGTTTTTTTTTCTAATAAA
CTTTTTATTTATATTTTTGTTTTATGTTATTATATTTGCAAAATAAAGTA
TAATGAGTTTTGGGTTATGTTTATTTTCATCGGAA
back to top

protein sequence of SMED30023854-orf-1

>SMED30023854-orf-1 ID=SMED30023854-orf-1|Name=SMED30023854-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=325bp
MRIILCFGIIIASFVIRSDSVLDVHESSSDNWGYKEGQSFKGPSQWWQLP
NTTCGGQRQSPIDIVPKFTIYWEDLKLPIISRINSINHSVTIEKHFASIY
LNFNDNWKITFGGNGCLKPVAVHWHWGSSNYIGSEHRLQGTRFPMEGHLV
SYDCGLYSSFQQASVSPNGLHVIGFFYRVGLNNPAITMVASAIKSHMKLK
TFSVNVSEIPPKDILPLELMNYYRYEGSLTTPPCTQNVIWTVLRSVQDIS
EDQLSVFRNLVFGDPEFGKLVNNFRPIFPIEKSTDYILRVVYASFNYSSK
LMTNFVLPAFILLLTPFFNNYLRK*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0016829lyase activity
GO:0008270zinc ion binding
GO:0004089carbonate dehydratase activity
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000034epidermis
Vocabulary: INTERPRO
TermDefinition
IPR036398CA_dom_sf
IPR023561Carbonic_anhydrase_a-class
IPR001148CA_dom
IPR018338Carbonic_anhydrase_a-class_CS
Vocabulary: biological process
TermDefinition
GO:0006730one-carbon metabolic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001148Alpha carbonic anhydrase domainSMARTSM01057Carb_anhydrase_2acoord: 32..295
e-value: 2.2E-58
score: 210.0
IPR001148Alpha carbonic anhydrase domainPFAMPF00194Carb_anhydrasecoord: 31..281
e-value: 3.9E-60
score: 203.5
IPR001148Alpha carbonic anhydrase domainPROSITEPS51144ALPHA_CA_2coord: 30..295
score: 49.877
IPR036398Alpha carbonic anhydrase domain superfamilyGENE3DG3DSA:3.10.200.10coord: 23..296
e-value: 6.8E-66
score: 224.4
IPR036398Alpha carbonic anhydrase domain superfamilySUPERFAMILYSSF51069Carbonic anhydrasecoord: 31..281
IPR023561Carbonic anhydrase, alpha-classPANTHERPTHR18952CARBONIC ANHYDRASEcoord: 11..291
NoneNo IPR availablePANTHERPTHR18952:SF197coord: 11..291
NoneNo IPR availableCDDcd00326alpha_CAcoord: 56..280
e-value: 5.33762E-63
score: 197.505
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..20
score: 0.683
NoneNo IPR availableTMHMMTMhelixcoord: 305..322
IPR018338Carbonic anhydrase, alpha-class, conserved sitePROSITEPS00162ALPHA_CA_1coord: 134..150