Thioredoxin reductase

Overview
NameThioredoxin reductase
Smed IDSMED30023830
Length (bp)1937
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Thioredoxin reductase (SMED30023830) t-SNE clustered cells

Violin plots show distribution of expression levels for Thioredoxin reductase (SMED30023830) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Thioredoxin reductase (SMED30023830) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Thioredoxin reductase (SMED30023830) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023830

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30023830SMESG000063651.1 SmedASXL_015193SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30023830SMESG000063651.1 SmedASXL_015193SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30023830SMESG000063651.1 dd_Smed_v4_4969_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30023830SMESG000063651.1 dd_Smed_v4_4969_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30023830SMESG000063651.1 dd_Smed_v4_4969_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Human
Match: TXNRD2 (thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155])

HSP 1 Score: 504.212 bits (1297), Expect = 6.438e-173
Identity = 275/516 (53.29%), Postives = 345/516 (66.86%), Query Frame = 3 
Query:  195 TRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPD-IPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQ-RPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            T++ A GV+         + YDL+VVGGGSGGLACAKEAA  G++VAV+DYV PS +GT WGLGGTCVNVGCIPKKLMH  A +  +I+ A + GW      P     DW  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+      G E  + A + +IA GGRPRYP  I GA +YGITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTT+M+RSIPLRGFD+QM+ MV EHM      +F+ G  P  +     G+ +V ++      E +  +DT+L+AIGR P T  LNL    V     T+KI   S+      E T+ P+IYAIGDV++   ELTP+AI AG+LL +RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+ R G ++ EVYH  +KPLE    G     CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+ I+KRS +DP +TGC G
Sbjct:   19 TQAVAGGVRGAARGAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPH----DWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASH-GTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSR------EATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCUG 523
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Human
Match: TXNRD2 (thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155])

HSP 1 Score: 498.049 bits (1281), Expect = 6.810e-171
Identity = 271/496 (54.64%), Postives = 337/496 (67.94%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQ-RPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            YDL+VVGGGSGGLACAKEAA  G++VAV+DYV PS +GT WGLGGTCVNVGCIPKKLMH  A +  +I+ A + GW      P     DW  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+      G E  + A + +IA GGRPRYP  I GA +YGITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTT+M+RSIPLRGFD+QM+ MV EHM      +F+ G  P  +     G+ +V ++      E +  +DT+L+AIGR P T  LNL    V     T+KI   S+      E T+ P+IYAIGDV++   ELTP+AI AG+LL +RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+ R G ++ EVYH  +KPLE    G     CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+ I+KRS +DP +TGC G
Sbjct:   10 YDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPH----DWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHM-ASHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSR------EATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCUG 494
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Human
Match: TXNRD2 (thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155])

HSP 1 Score: 498.819 bits (1283), Expect = 7.571e-171
Identity = 271/496 (54.64%), Postives = 337/496 (67.94%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPD-IPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQ-RPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            YDL+VVGGGSGGLACAKEAA  G++VAV+DYV PS +GT WGLGGTCVNVGCIPKKLMH  A +  +I+ A + GW      P     DW  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+      G E  + A + +IA GGRPRYP  I GA +YGITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTT+M+RSIPLRGFD+QM+ MV EHM      +F+ G  P  +     G+ +V ++      E +  +DT+L+AIGR P T  LNL    V     T+KI   S+      E T+ P+IYAIGDV++   ELTP+AI AG+LL +RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+ R G ++ EVYH  +KPLE    G     CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+ I+KRS +DP +TGC G
Sbjct:   40 YDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPH----DWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASH-GTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSR------EATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCUG 524
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Human
Match: TXNRD2 (thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155])

HSP 1 Score: 484.952 bits (1247), Expect = 9.477e-166
Identity = 252/475 (53.05%), Postives = 317/475 (66.74%), Query Frame = 3 
Query:  318 FGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQ-RPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
             G++VAV+DYV PS +GT WGLGGTCVNVGCIPKKLMH  A +  +I+ A + GW      P     DW  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+      G E  + A + +IA GGRPRYP  I GA +YGITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTT+M+RSIPLRGFD+QM+ MV EHM      +F+ G  P  +     G+ +V ++      E +  +DT+L+AIGR P T  LNL    V     T+KI   S+      E T+ P+IYAIGDV++   ELTP+AI AG+LL +RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+ R G ++ EVYH  +KPLE    G     CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+ I+KRS +DP +TGC G
Sbjct:   38 LGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPH----DWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASH-GTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSR------EATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCUG 501
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Human
Match: TXNRD1 (thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437])

HSP 1 Score: 461.07 bits (1185), Expect = 2.207e-156
Identity = 249/482 (51.66%), Postives = 316/482 (65.56%), Query Frame = 3 
Query:  303 KEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ---GKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            KEAA +GK+V VLD+V+P+  GT WGLGGTCVNVGCIPKKLMH  A +   ++ + + GW       +++  DW  M   VQN++ SLNWG+RV+LRE KV Y NA  +F     I AT++KG EK   A+ F+IA G RPRY  IPG K+Y I+SDDLF L   PGKTLVVG SYVALECAGFL   G D TVMVRSI LRGFD+ MA  + EHME E  IKFI    P+ + + E    G+ RV  +   +   +   Y+T++ AIGRD CT  + L  V V ++E T KI         D E+T  P IYAIGD+L+D VELTPVAI+AG+LLA+RL+   T + +Y  +PTTVFTPLEY   G++EE+A+ + G++N EVYH +F PLE  I       CY K+IC+   +ERVVG H+LG NAGEV QGFAAA+K G+T KQL +T+GIHP  AE    + +TKRS       GC G
Sbjct:   29 KEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKV----EETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHME-EHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPV------TDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGCUG 499
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Celegans
Match: trxr-1 (Thioredoxin reductase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q17745])

HSP 1 Score: 410.994 bits (1055), Expect = 2.200e-135
Identity = 247/507 (48.72%), Postives = 318/507 (62.72%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ------GKFRVKY-KKEKNPGEMSDV---YDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRP-CYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRS-HVDPHLTGC*G 1736
            YDL+V+GGGSGGLA AKEA+  GK+VA LD+V PS +GTSWGLGGTCVNVGCIPKKLMH  + +   I  A   GW     K +     W  +   VQ+++ SLNWG+RV LRE  V YIN+  +F     I+AT+ K   +++ A  F+I+ G RP+YP+IPG K+Y ITSDDLF L  SPGKTL VG SYV+LECAGFLH FG D TVMVRSI LRGFD+ MAE + +HM     +KF  G  P  I + ++      GK+RV + KK +  GEM +V   Y+TIL AIGR+  T D+ L+ + V   +  K +    +S       TT P +YAIGDVL+   ELTPVAI+AG++L RR+F+       Y+ IPTTVFTPLEY C G++EE+A+ + G  N  +YH  F PLE  IS  + +  CY+KMIC     E+VVG HIL  NAGEV QGF  A+K           +GIHPT AE    + + K+    +   +GC G
Sbjct:  140 YDLIVIGGGSGGLAAAKEASRLGKKVACLDFVKPSPQGTSWGLGGTCVNVGCIPKKLMHQASLLGHSIHDAKKYGWKLPEGKVEH---QWNHLRDSVQDHIASLNWGYRVQLREKTVTYINSYGEFTGPFEISATNKKKKVEKLTADRFLISTGLRPKYPEIPGVKEYTITSDDLFQLPYSPGKTLCVGASYVSLECAGFLHGFGFDVTVMVRSILLRGFDQDMAERIRKHM-IAYGMKFEAGV-PTRIEQIDEKTDEKAGKYRVFWPKKNEETGEMQEVSEEYNTILMAIGREAVTDDVGLTTIGVERAKSKKVLGRREQS-------TTIPWVYAIGDVLEGTPELTPVAIQAGRVLMRRIFDGANELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDNIIIYHNVFNPLEYTISERMDKDHCYLKMICLRNEEEKVVGFHILTPNAGEVTQGFGIALKLAAKKADFDRLIGIHPTVAENFTTLTLEKKEGDEELQASGCUG 634
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Celegans
Match: trxr-1 (Thioredoxin reductase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q17745])

HSP 1 Score: 410.609 bits (1054), Expect = 6.953e-135
Identity = 247/507 (48.72%), Postives = 318/507 (62.72%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ------GKFRVKY-KKEKNPGEMSDV---YDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRP-CYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRS-HVDPHLTGC*G 1736
            YDL+V+GGGSGGLA AKEA+  GK+VA LD+V PS +GTSWGLGGTCVNVGCIPKKLMH  + +   I  A   GW     K +     W  +   VQ+++ SLNWG+RV LRE  V YIN+  +F     I+AT+ K   +++ A  F+I+ G RP+YP+IPG K+Y ITSDDLF L  SPGKTL VG SYV+LECAGFLH FG D TVMVRSI LRGFD+ MAE + +HM     +KF  G  P  I + ++      GK+RV + KK +  GEM +V   Y+TIL AIGR+  T D+ L+ + V   +  K +    +S       TT P +YAIGDVL+   ELTPVAI+AG++L RR+F+       Y+ IPTTVFTPLEY C G++EE+A+ + G  N  +YH  F PLE  IS  + +  CY+KMIC     E+VVG HIL  NAGEV QGF  A+K           +GIHPT AE    + + K+    +   +GC G
Sbjct:  173 YDLIVIGGGSGGLAAAKEASRLGKKVACLDFVKPSPQGTSWGLGGTCVNVGCIPKKLMHQASLLGHSIHDAKKYGWKLPEGKVEH---QWNHLRDSVQDHIASLNWGYRVQLREKTVTYINSYGEFTGPFEISATNKKKKVEKLTADRFLISTGLRPKYPEIPGVKEYTITSDDLFQLPYSPGKTLCVGASYVSLECAGFLHGFGFDVTVMVRSILLRGFDQDMAERIRKHM-IAYGMKFEAGV-PTRIEQIDEKTDEKAGKYRVFWPKKNEETGEMQEVSEEYNTILMAIGREAVTDDVGLTTIGVERAKSKKVLGRREQS-------TTIPWVYAIGDVLEGTPELTPVAIQAGRVLMRRIFDGANELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDNIIIYHNVFNPLEYTISERMDKDHCYLKMICLRNEEEKVVGFHILTPNAGEVTQGFGIALKLAAKKADFDRLIGIHPTVAENFTTLTLEKKEGDEELQASGCUG 667
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Celegans
Match: trxr-2 (Probable glutathione reductase 2 [Source:UniProtKB/Swiss-Prot;Acc:P30635])

HSP 1 Score: 403.29 bits (1035), Expect = 3.744e-134
Identity = 231/502 (46.02%), Postives = 315/502 (62.75%), Query Frame = 3 
Query:  243 SSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKF--KDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRP--CYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            SS  +DL+V+G GSGGL+C+K AA  G  VA++D V P+  G SWG+GGTC NVGCIPKKLMH  A +   ++ A   GWN I+   + +  DW +++  V + VK+ NW +RV L + K+ Y NA A+F  KD   IT TD    +  + A N VI+ G RP+YP+IPGA + GITSDDLF L   PGKTL+VGG YVALECAGFL AF  +  V+VRSIPL+GFDR     V EH+ K   +K     E V  +EA   K +V +       E    YDT+++A GR P    LNL    V  D+ + KI +       + ++ +   +YA+GD+++D  ELTP+AI++GKLLA RLF+N    + ++ + TTVFTPLE + VG+TEEEAI + G+ + EV+H  F P E +    +    CY+K +C    S++++GLH +G NA EV+QG+A A + GI+   L NT+ IHP S+EE VK+HITKRS  DP   GC G
Sbjct:   17 SSNKFDLIVIGAGSGGLSCSKRAADLGANVALIDAVEPTPHGHSWGIGGTCANVGCIPKKLMHQAAIVGKELKHADKYGWNGID--QEKIKHDWNVLSKNVNDRVKANNWIYRVQLNQKKINYFNAYAEFVDKDKIVITGTDKNKTKNFLSAPNVVISTGLRPKYPNIPGA-ELGITSDDLFTLASVPGKTLIVGGGYVALECAGFLSAFNQNVEVLVRSIPLKGFDRDCVHFVMEHL-KTTGVKVKEHVE-VERVEAVGSKKKVTFTGNGGVEE----YDTVIWAAGRVPNLKSLNLDNAGVRTDKRSGKILAD------EFDRASCNGVYAVGDIVQDRQELTPLAIQSGKLLADRLFSNSKQIVRFDGVATTVFTPLELSTVGLTEEEAIQKHGEDSIEVFHSHFTPFEYVVPQNKDSGFCYVKAVCTRDESQKILGLHFVGPNAAEVIQGYAVAFRVGISMSDLQNTIAIHPCSSEEFVKLHITKRSGQDPRTQGCCG 503
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Celegans
Match: gsr-1 (Glutathione reductase, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:Q93379])

HSP 1 Score: 238.039 bits (606), Expect = 4.456e-71
Identity = 188/512 (36.72%), Postives = 277/512 (54.10%), Query Frame = 3 
Query:  189 SATRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVR-SIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVS-IIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNET-GQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDP 1715
            S +RS  SGVK           +D +V+GGGSGG+A A+ A  FG  V +++         S  LGGTCVNVGC+PKK+M++ +   + I    D G++    K      DW ++      Y+K LN  +   L+ + VEYI  +A F +  T+    +K      + KN +IAVGG+P  P+I GA ++GI SD  F L+  P +T+VVG  Y+A+E AG L   G DT +++R    LR FD+ +++ +   M++E     ++    V+ +I+ + G   +K       G +  V  T+++AIGRDP T +LNL  V      G K   SG    + + + T+AP I ++GD     + LTPVAI AG+ L+ RLFN ET  ++ Y  I T VF+      VG+TE EA+ + G     +Y   F P+       +    MK++C +G  E+VVG+H+ G+ + E+LQGFA A+  G T KQ   TV IHPTSAEE+V    T R  V P
Sbjct:    9 STSRSIMSGVKE----------FDYLVIGGGSGGIASARRAREFGVSVGLIE---------SGRLGGTCVNVGCVPKKVMYNCSLHAEFIRDHADYGFDVTLNK-----FDWKVIKKSRDEYIKRLNGLYESGLKGSSVEYIRGRATFAEDGTVEVNGAK-----YRGKNTLIAVGGKPTIPNIKGA-EHGIDSDGFFDLEDLPSRTVVVGAGYIAVEIAGVLANLGSDTHLLIRYDKVLRTFDKMLSDELTADMDEETNPLHLHKNTQVTEVIKGDDGLLTIK----TTTGVIEKV-QTLIWAIGRDPLTKELNLERV------GVKTDKSGHIIVD-EYQNTSAPGILSVGDDTGKFL-LTPVAIAAGRRLSHRLFNGETDNKLTYENIATVVFSHPLIGTVGLTEAEAVEKYGKDEVTLYKSRFNPMLFAVTKHKEKAAMKLVC-VGKDEKVVGVHVFGVGSDEMLQGFAVAVTMGATKKQFDQTVAIHPTSAEELV----TMRGGVKP 472
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Celegans
Match: gsr-1 (Glutathione reductase, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:Q93379])

HSP 1 Score: 235.728 bits (600), Expect = 2.533e-70
Identity = 167/451 (37.03%), Postives = 247/451 (54.77%), Query Frame = 3 
Query:  372 SWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVR-SIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVS-IIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNET-GQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDP 1715
            S  LGGTCVNVGC+PKK+M++ +   + I    D G++    K      DW ++      Y+K LN  +   L+ + VEYI  +A F +  T+    +K      + KN +IAVGG+P  P+I GA ++GI SD  F L+  P +T+VVG  Y+A+E AG L   G DT +++R    LR FD+ +++ +   M++E     ++    V+ +I+ + G   +K       G +  V  T+++AIGRDP T +LNL  V      G K   SG    + + + T+AP I ++GD     + LTPVAI AG+ L+ RLFN ET  ++ Y  I T VF+      VG+TE EA+ + G     +Y   F P+       +    MK++C +G  E+VVG+H+ G+ + E+LQGFA A+  G T KQ   TV IHPTSAEE+V    T R  V P
Sbjct:   37 SGRLGGTCVNVGCVPKKVMYNCSLHAEFIRDHADYGFDVTLNK-----FDWKVIKKSRDEYIKRLNGLYESGLKGSSVEYIRGRATFAEDGTVEVNGAK-----YRGKNTLIAVGGKPTIPNIKGA-EHGIDSDGFFDLEDLPSRTVVVGAGYIAVEIAGVLANLGSDTHLLIRYDKVLRTFDKMLSDELTADMDEETNPLHLHKNTQVTEVIKGDDGLLTIK----TTTGVIEKV-QTLIWAIGRDPLTKELNLERV------GVKTDKSGHIIVD-EYQNTSAPGILSVGDDTGKFL-LTPVAIAAGRRLSHRLFNGETDNKLTYENIATVVFSHPLIGTVGLTEAEAVEKYGKDEVTLYKSRFNPMLFAVTKHKEKAAMKLVC-VGKDEKVVGVHVFGVGSDEMLQGFAVAVTMGATKKQFDQTVAIHPTSAEELV----TMRGGVKP 458
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Fly
Match: Trxr-1 (gene:FBgn0020653 transcript:FBtr0071169)

HSP 1 Score: 474.937 bits (1221), Expect = 5.562e-162
Identity = 267/500 (53.40%), Postives = 333/500 (66.60%), Query Frame = 3 
Query:  240 NSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSER-GTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWN-QINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            N S  YDL+V+GGGS GLACAKEA L G +VA LD+V P+   GT WG+GGTCVNVGCIPKKLMH  + + + +  A   GWN    +KP     DW  +   VQN++KS+NW  RV LR+ KVEYIN    F D+ T+ A    G E+ I A+ FVIAVGGRPRYPDIPGA +YGITSDDLF L + PGKTLVVG  Y+ LECAGFL   G + TVMVRSI LRGFD+QMAE+VA  ME ER I F+    P+S+ + + GK  VKYK  +   E  DVYDT+L+AIGR     DLNL    V+V +   KI   S+      E T   NIYA+GD++    ELTPVA+ AG+LLARRL+   T +M+Y  + TTVFTPLEYACVG++EE+A+ + G    EV+H ++KP E  I     R CY+K + +    +RV GLH +G  AGEV+QGFAAA+K G+T   L NTVGIHPT+AEE  ++ ITKRS +DP    C
Sbjct:   22 NGSYDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNVDEKIKP-----DWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLKSG-ERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASME-ERGIPFLRKTVPLSVEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQK--DKIPVDSQ------EATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSGLDPTPASC 506
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BLAST of Thioredoxin reductase vs. Ensembl Fly
Match: Trxr-1 (gene:FBgn0020653 transcript:FBtr0071167)

HSP 1 Score: 472.241 bits (1214), Expect = 3.451e-161
Identity = 265/495 (53.54%), Postives = 331/495 (66.87%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSER-GTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWN-QINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDL+V+GGGS GLACAKEA L G +VA LD+V P+   GT WG+GGTCVNVGCIPKKLMH  + + + +  A   GWN    +KP     DW  +   VQN++KS+NW  RV LR+ KVEYIN    F D+ T+ A    G E+ I A+ FVIAVGGRPRYPDIPGA +YGITSDDLF L + PGKTLVVG  Y+ LECAGFL   G + TVMVRSI LRGFD+QMAE+VA  ME ER I F+    P+S+ + + GK  VKYK  +   E  DVYDT+L+AIGR     DLNL    V+V +   KI   S+      E T   NIYA+GD++    ELTPVA+ AG+LLARRL+   T +M+Y  + TTVFTPLEYACVG++EE+A+ + G    EV+H ++KP E  I     R CY+K + +    +RV GLH +G  AGEV+QGFAAA+K G+T   L NTVGIHPT+AEE  ++ ITKRS +DP    C
Sbjct:   10 YDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNVDEKIKP-----DWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLKSG-ERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASME-ERGIPFLRKTVPLSVEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQK--DKIPVDSQ------EATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSGLDPTPASC 489
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BLAST of Thioredoxin reductase vs. Ensembl Fly
Match: Trxr-1 (gene:FBgn0020653 transcript:FBtr0071168)

HSP 1 Score: 472.626 bits (1215), Expect = 8.510e-160
Identity = 265/495 (53.54%), Postives = 331/495 (66.87%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSER-GTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWN-QINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDL+V+GGGS GLACAKEA L G +VA LD+V P+   GT WG+GGTCVNVGCIPKKLMH  + + + +  A   GWN    +KP     DW  +   VQN++KS+NW  RV LR+ KVEYIN    F D+ T+ A    G E+ I A+ FVIAVGGRPRYPDIPGA +YGITSDDLF L + PGKTLVVG  Y+ LECAGFL   G + TVMVRSI LRGFD+QMAE+VA  ME ER I F+    P+S+ + + GK  VKYK  +   E  DVYDT+L+AIGR     DLNL    V+V +   KI   S+      E T   NIYA+GD++    ELTPVA+ AG+LLARRL+   T +M+Y  + TTVFTPLEYACVG++EE+A+ + G    EV+H ++KP E  I     R CY+K + +    +RV GLH +G  AGEV+QGFAAA+K G+T   L NTVGIHPT+AEE  ++ ITKRS +DP    C
Sbjct:  115 YDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNVDEKIKP-----DWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLKSG-ERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASME-ERGIPFLRKTVPLSVEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQK--DKIPVDSQ------EATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSGLDPTPASC 594
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Fly
Match: Trxr-2 (gene:FBgn0037170 transcript:FBtr0078514)

HSP 1 Score: 452.981 bits (1164), Expect = 2.970e-153
Identity = 245/501 (48.90%), Postives = 325/501 (64.87%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWN--QINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVE-KEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDL-----EKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDLVV+GGGS GLACAKEAA  G +V   DYV P+  GT WG+GGTCVNVGCIPKKLMH  + + + +  A   GWN    N++P     DW  +   VQN++KS+NW  RV LR+ KVEY+N+ A F+D+ TI      G E +++ ++  V+AVGGRPRYPDIPGA + GITSDD+F  ++ PG+TLVVG  YV LECA FL   G + TVMVRSI LRGFDRQM+E++A  M  ER I F+    P ++     G+  V+Y+      + SDV+DT+L+AIGR               + E      +G K+++  +     E T+ P+I+A+GD++    ELTPVAI +G+LLARRLF   T  M+Y  + TTVFTPLEY+CVGM+EE AI   G  N EV+H ++KP E  I     R CY+K + ++   ++++GLH +G  AGEV+QGFAAA+K G+T K L NTVGIHPT+AEE  ++ ITKRS  DP    C
Sbjct:   33 YDLVVLGGGSAGLACAKEAAGCGARVLCFDYVKPTPVGTKWGIGGTCVNVGCIPKKLMHQASLLGEAVHEAVAYGWNVDDTNIRP-----DWRKLVRSVQNHIKSVNWVTRVDLRDKKVEYVNSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPRYPDIPGAVELGITSDDIFSYEREPGRTLVVGAGYVGLECACFLKGLGYEPTVMVRSIVLRGFDRQMSELLAAMM-TERGIPFLGTTIPKAVERQADGRLLVRYRNTTTQMDGSDVFDTVLWAIGR-------------KGLIEDLNLDAAGVKTHDDKIVVDAAEATSVPHIFAVGDIIYGRPELTPVAILSGRLLARRLFAGSTQLMDYADVATTVFTPLEYSCVGMSEETAIELRGADNIEVFHGYYKPTEFFIPQKSVRHCYLKAVAEVSGDQKILGLHYIGPVAGEVIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFTRLSITKRSGRDPTPASC 514
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Fly
Match: CG7430 (gene:FBgn0036762 transcript:FBtr0075140)

HSP 1 Score: 103.605 bits (257), Expect = 5.958e-23
Identity = 136/518 (26.25%), Postives = 223/518 (43.05%), Query Frame = 3 
Query:  147 FSMRFCRYAIIVTYSATRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLM---HHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGR-PRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVM--VRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVY-DTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQR---PCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAE 1670
            F++R    A+  T   T +   G  +N    +S+   D+VV+G G GG   A +AA  G     +  VS  +  T   LGGTC+NVGCIP K +    H   M      AH     +  +   S+ +D   +     N VK+L  G  +  ++NKV  +       +   +    S G  + +K KN +IA G     +P I   ++  ++S     L K P   +V+G   + LE        G + T +  + +I   G D ++++   + + K+  +KF  G + V+          V  +  K+ GE  ++  D +L ++GR P T  L L  V      G  K   G        + T  PNIYAIGD +  G  L   A   G L+     N     ++YN +P+ V+T  E A VG +EE+       +    Y     P    S          ++K++ D   +++++G HI+G  AGE++     A++ G   + ++     HPT +E
Sbjct:    3 FTLRHVVSAVAKTPLRTNAAILGA-LNARCYSSTHEADIVVIGSGPGGYVAAIKAAQMG-----MKTVSVEKEAT---LGGTCLNVGCIPSKALLNNSHYYHM------AHSGDLEKRGISCGSVSLDLEKLMGQKSNAVKALTGGIAMLFKKNKVTQLTGFGTIVNPNEVEVKKSDGSTETVKTKNILIATGSEVTPFPGIEIDEEVIVSSTGALKLAKVPKHLVVIGAGVIGLELGSVWSRLGAEVTAIEFMDTIGGVGIDNEVSKTFQKVLTKQ-GLKFKLGTK-VTAASRSGDNVTVSVENAKS-GEKEEIQCDALLVSVGRRPYTEGLGLEAV------GIVKDDRGRIPVNATFQ-TVVPNIYAIGDCIH-GPMLAHKAEDEG-LITIEGINGGHVHIDYNCVPSVVYTHPEVAWVGKSEEQL-----KQEGVAYKVGKFPFLANSRAKTNNDTDGFVKVLADQA-TDKILGTHIIGPGAGELINEAVLAMEYGAAAEDVARVCHAHPTCSE 487
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Zebrafish
Match: txnrd2.2 (thioredoxin reductase 2, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-040914-66])

HSP 1 Score: 488.804 bits (1257), Expect = 3.810e-167
Identity = 262/494 (53.04%), Postives = 340/494 (68.83%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPD-IPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDLVV+GGGSGGLAC+KEAA  G++VAVLDYV PS +GT WGLGGTCVNVGCIPKKLMH  A +   ++ A   GW QI   P++L  DWP MA  VQN+V+SLNWGHRV L++ KV+Y+N K    D  T+ A +++G E  + A+N ++A GGRP+YP  +PGA ++GITSDD+FWLK+SP KTL++G SYV+LECAGFL   G DT+VMVRSI LRGFD+QM+ +V ++ME     KF +   P S+ +   G  +V +       E  D ++++L+A+GR P T  LNL  V V +++ T KI   +       E T+ PNI+AIGD+ +   ELTP AIKAGKLLA RL    T  MNY  + TTVFTPLEY CVG++EEEA  R G    EVYH F+KPLE  ++      CY+K++C     +RV+GLH  G NAGEV QGFA   + G+T++ L NTVGIHPT AEE+ K++ITKRS +D  +TGC
Sbjct:   33 YDLVVIGGGSGGLACSKEAAQLGQKVAVLDYVEPSLKGTKWGLGGTCVNVGCIPKKLMHQAALLGTAVKDARKYGW-QI---PETLSHDWPTMAEAVQNHVRSLNWGHRVQLQDKKVKYLNMKGTLLDKHTVRAVNAQGKEMTVTARNILLATGGRPKYPTHVPGAMEFGITSDDIFWLKESPKKTLIIGASYVSLECAGFLTGIGLDTSVMVRSIALRGFDQQMSGLVTDYMET-YGTKFHWKCTPKSVEKLPSGHLQVTWMDLNTKEEHQDTFNSVLWAVGRAPETKTLNLEKVGVKINKETGKIIVAAD------EATSVPNIFAIGDIGEGRPELTPTAIKAGKLLAHRLAGRSTELMNYENVATTVFTPLEYGCVGLSEEEAERRHGKDQIEVYHAFYKPLEFTVAERDATQCYIKVVCLREGDQRVLGLHFTGPNAGEVTQGFALGFQCGLTYEHLRNTVGIHPTCAEELTKLNITKRSGLDATVTGC 515
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Zebrafish
Match: txnrd3 (thioredoxin reductase 3 [Source:ZFIN;Acc:ZDB-GENE-030327-3])

HSP 1 Score: 449.129 bits (1154), Expect = 1.850e-150
Identity = 253/498 (50.80%), Postives = 316/498 (63.45%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ---GKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGL-QRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            YDL+V+GGGSGGLAC+KEAA  GK+V VLDYV P+ +GT+WGLGGTCVNVGCIPKKLMH  A +   +E A   GW       + +  +W  M + V NY+ SLNWG+RVSLR+  V Y+NA A+F +   I AT+ +G E    A  FV+A G RPRY  IPG K++ ITSDDLF L   PGKTLVVG SYVALEC GFL   G D T+MVRSI LRGFD+ MA+   E+ME    +KF+    P  I + E    G+ +V  K  ++       Y+T+L A+GRD CT  + L    V ++E   K+         D E+T  P+IYAIGD+L+   ELTPVAI+AGKLLARRL+   T + +Y  +PTTVFTP+EY   G  EE+AI   G +N EVYH  F PLE    G     CY K+IC+   + RV+G H LG NAGEV QGF AA+K GIT  QL NT+GIHPT AE    + +TK S  D   +GC G
Sbjct:  116 YDLIVIGGGSGGLACSKEAATLGKKVMVLDYVVPTPQGTAWGLGGTCVNVGCIPKKLMHQTALLGTAMEDARKFGWEF----AEQVTHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNAYAEFVEPHKIKATNKRGKETFYTAAQFVLATGERPRYLGIPGDKEFCITSDDLFSLPYCPGKTLVVGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMADRAGEYMET-HGVKFLRKFVPTKIEQLEAGTPGRIKVTAKSTESEEVFEGEYNTVLIAVGRDACTGKIGLDKAGVKINEKNGKVPVN------DEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGATMKCDYVNVPTTVFTPMEYGSCGHPEEKAIQMYGQENLEVYHSLFWPLEFTVPGRDNNKCYAKIICNKLDNLRVIGFHYLGPNAGEVTQGFGAAMKCGITKDQLDNTIGIHPTCAEIFTTMEVTKSSGGDITQSGCUG 602
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Zebrafish
Match: txnrd3 (thioredoxin reductase 3 [Source:ZFIN;Acc:ZDB-GENE-030327-3])

HSP 1 Score: 448.743 bits (1153), Expect = 2.276e-150
Identity = 252/496 (50.81%), Postives = 315/496 (63.51%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ---GKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGL-QRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDL+V+GGGSGGLAC+KEAA  GK+V VLDYV P+ +GT+WGLGGTCVNVGCIPKKLMH  A +   +E A   GW       + +  +W  M + V NY+ SLNWG+RVSLR+  V Y+NA A+F +   I AT+ +G E    A  FV+A G RPRY  IPG K++ ITSDDLF L   PGKTLVVG SYVALEC GFL   G D T+MVRSI LRGFD+ MA+   E+ME    +KF+    P  I + E    G+ +V  K  ++       Y+T+L A+GRD CT  + L    V ++E   K+         D E+T  P+IYAIGD+L+   ELTPVAI+AGKLLARRL+   T + +Y  +PTTVFTP+EY   G  EE+AI   G +N EVYH  F PLE    G     CY K+IC+   + RV+G H LG NAGEV QGF AA+K GIT  QL NT+GIHPT AE    + +TK S  D   +GC
Sbjct:  116 YDLIVIGGGSGGLACSKEAATLGKKVMVLDYVVPTPQGTAWGLGGTCVNVGCIPKKLMHQTALLGTAMEDARKFGWEF----AEQVTHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNAYAEFVEPHKIKATNKRGKETFYTAAQFVLATGERPRYLGIPGDKEFCITSDDLFSLPYCPGKTLVVGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMADRAGEYMET-HGVKFLRKFVPTKIEQLEAGTPGRIKVTAKSTESEEVFEGEYNTVLIAVGRDACTGKIGLDKAGVKINEKNGKVPVN------DEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGATMKCDYVNVPTTVFTPMEYGSCGHPEEKAIQMYGQENLEVYHSLFWPLEFTVPGRDNNKCYAKIICNKLDNLRVIGFHYLGPNAGEVTQGFGAAMKCGITKDQLDNTIGIHPTCAEIFTTMEVTKSSGGDITQSGC 600
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Zebrafish
Match: txnrd2.2 (thioredoxin reductase 2, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-040914-66])

HSP 1 Score: 300.056 bits (767), Expect = 1.443e-96
Identity = 152/282 (53.90%), Postives = 202/282 (71.63%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAI 1097
            YDLVV+GGGSGGLAC+KEAA  G++VAVLDYV PS +GT WGLGGTCVNVGCIPKKLMH  A +   ++ A   GW QI   P++L  DWP MA  VQN+V+SLNWGHRV L++ KV+Y+N K    D  T+ A +++G E  + A+N ++A GGRP+YP  +PGA ++GITSDD+FWLK+SP KTL++G SYV+LECAGFL   G DT+VMVRSI LRGFD+QM+ +V ++ME     KF +   P S+ +   G  +V +       E  D ++++L+A+
Sbjct:   33 YDLVVIGGGSGGLACSKEAAQLGQKVAVLDYVEPSLKGTKWGLGGTCVNVGCIPKKLMHQAALLGTAVKDARKYGW-QI---PETLSHDWPTMAEAVQNHVRSLNWGHRVQLQDKKVKYLNMKGTLLDKHTVRAVNAQGKEMTVTARNILLATGGRPKYPTHVPGAMEFGITSDDIFWLKESPKKTLIIGASYVSLECAGFLTGIGLDTSVMVRSIALRGFDQQMSGLVTDYME-TYGTKFHWKCTPKSVEKLPSGHLQVTWMDLNTKEEHQDTFNSVLWAV 309
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Zebrafish
Match: gsr (glutathione reductase [Source:ZFIN;Acc:ZDB-GENE-050522-116])

HSP 1 Score: 227.639 bits (579), Expect = 1.116e-66
Identity = 176/507 (34.71%), Postives = 263/507 (51.87%), Query Frame = 3 
Query:  198 RSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRY---PDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIP-LRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTI------LFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNET-GQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKI 1685
            RS ASG         S   +D +VVGGGSGGLA A+ AA  G   AV++         S  LGGTCVNVGC+PKK+M + +   + +    D G+             W I+      YV  LN  +R +L + K+E+I+  A+F D    T   +    K+  A + +I+ GG P      D+PG+   GITSD  F L+  P ++++VG  Y+A+E AG L   G  T++++R    LR FD  ++    + ++    I      +  S+ +  +G       K+ +  +  + +DTI      L+AIGR+P T+ LNLS + V +DE    +         + + T+ P +YA+GDV    + LTPVAI AG+ LA RLF  +   +++YN IPT VF+      VG+TE+EA+   G    +VY   F P+       +  C MK++C  G +E+VVGLH+ G    E+LQGFA A+  G T      T+ IHPTS+EE+V +
Sbjct:   30 RSMASG---------SVSRFDFLVVGGGSGGLAGARRAAELGATTAVIE---------SHRLGGTCVNVGCVPKKVMWNTSTHAEYLHDHEDYGFEGAKAH-----FSWQIIKHKRDAYVSRLNQIYRSNLEKGKIEFIHGYARFTDDPEPTVEVNG---KKYTATHILISTGGHPSTVSEDDVPGS-SLGITSDGFFELESCPKRSVIVGAGYIAVEMAGILSTLGSKTSIIIRQGGVLRNFDALISSNCTKELQNN-GIDLRKNTQVKSVKKNGKGLSITLVTKDPDDKDSQEKFDTINDVDCLLWAIGREPNTAGLNLSQIGVKLDERGHIVVD-------EFQNTSRPGVYAVGDVCGRAL-LTPVAIAAGRKLAHRLFEGKADSKVDYNNIPTVVFSHPPIGTVGLTEDEAVKTYGKDKVKVYTTSFTPMYYAITTRKSQCIMKLVC-AGENEKVVGLHMQGFGCDEMLQGFAVAVNMGATKADFDRTIAIHPTSSEELVTL 499
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Xenopus
Match: dpep1 (dipeptidase 1 [Source:Xenbase;Acc:XB-GENE-6043566])

HSP 1 Score: 466.077 bits (1198), Expect = 4.231e-158
Identity = 258/500 (51.60%), Postives = 329/500 (65.80%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPD-IPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEE----EAINRLGDK--NTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDL+V+GGGSGGLACAK+AA FGK+VAV DYV PS RGT WG+GGTCVNVGCIPKKLMH  A +   ++ A   GW+     P  +  +W  MA  VQNYVKSLNWGHR+ L++ KV+Y N KA F D   I      G E  + A+N VIA GGRP+YP  +PGA +YGITSDDLFWLK+SPGKTLVVG SYV+LECAGFL   G DT  MVRSIPLRGFD+QMA +V ++ME     KF++   P ++ + + GK  V +K  ++  E +D+YDT+++A+GR   T  LNL  V V V   T KI   +       E T+ P+IYAIGD+ +   ELTP AI AGKLLA RLF+     M+Y+ +    F  +EY C  +       +  +   +   + +V+H F+KPLE I++      CY+K+IC     +R++GLH  G NAGEV+QGFA  IK G T+ QL  TVGIHPT AEEV K+HITKRS +DP +TGC
Sbjct:   27 YDLLVIGGGSGGLACAKQAAQFGKKVAVFDYVEPSPRGTKWGIGGTCVNVGCIPKKLMHQAALIGSTLKDAPHYGWDT----PNEIQHNWGKMAKAVQNYVKSLNWGHRIQLQDKKVKYFNMKASFVDEHCIRGVTKAGKETLVTAENIVIATGGRPKYPTHVPGALEYGITSDDLFWLKESPGKTLVVGASYVSLECAGFLTGIGLDTAAMVRSIPLRGFDQQMAYLVTDYMEL-HGTKFLWKCTPSNVEKLKNGKLEVTWKNTESGKEGADIYDTVMWAVGRAAETQYLNLEKVGVDVKSDTGKIIVNAS------EATSVPHIYAIGDITEGRPELTPTAIAAGKLLASRLFSGSAELMDYDSVSNVWFPLIEYGCRAIMTSIFSFQVFHAFYNSIFSFQVFHAFYKPLEFIVAERNGSQCYIKIICLRTQDQRILGLHFTGPNAGEVIQGFALGIKCGATYHQLMRTVGIHPTCAEEVTKLHITKRSGLDPTVTGC 515
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Xenopus
Match: nmt1 (N-myristoyltransferase 1 [Source:Xenbase;Acc:XB-GENE-953051])

HSP 1 Score: 465.307 bits (1196), Expect = 1.391e-157
Identity = 263/503 (52.29%), Postives = 335/503 (66.60%), Query Frame = 3 
Query:  231 NVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGK-FRVKYKKEKNPG-EMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            N + S   YDL+V+GGGSGGLA +KEAA +GK+V VLD+V+P+  GT WGLGGTCVNVGCIPKKLMH  A +R  ++ +   GW QI    Q    +W IM   V NY+ SLN+ +RVSL +N V+Y N   +F +  TI +T+S+G EK   A+ F+IA G RPRY  IPG K+Y ITSDDLF L   PGKTLVVG SYVALECAGFL   G D TVMVRSI LRGFD+QMA M+ E+ME E  +KFI    P  I + E G   R+K   + + G E ++ Y+T+L AIGRD CT ++ L +  V ++E T KI         D E+T  P IYAIGDVL+D +ELTPVAI+AG+LLARRL+ + T + +Y  +PTTVFTPLEY   G++EE AI +  ++N EVYH +F PLE  +       CY K+IC++    RVVG H+L  NAGE+ QGFA AIK G+T  QL NT+GIHP  AE    + +TKRS  +   +GC
Sbjct:   40 NPDRSGYDYDLIVIGGGSGGLAASKEAANYGKKVLVLDFVTPTPLGTKWGLGGTCVNVGCIPKKLMHQAALLRQALKDSQKYGW-QIEDNIQH---NWEIMTDSVLNYIGSLNFNYRVSLMQNNVKYENGYGEFVEPHTIKSTNSRGKEKYFTAEKFLIATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQQMANMIGEYME-EHGVKFIKQCVPTKIEQIEAGTPGRLKVTSQASDGAETTEEYNTVLLAIGRDACTRNIGLEIPGVKINEKTGKIPVN------DEEQTNVPYIYAIGDVLQDKLELTPVAIQAGRLLARRLYGDSTVKCDYVNVPTTVFTPLEYGACGLSEEHAIRQYEEENIEVYHSYFWPLEWTVPARDNNKCYAKIICNLKDKGRVVGFHVLSPNAGEITQGFAVAIKCGLTKDQLDNTIGIHPVCAEIFTTLTVTKRSGGNILQSGC 531
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Xenopus
Match: nmt1 (N-myristoyltransferase 1 [Source:Xenbase;Acc:XB-GENE-953051])

HSP 1 Score: 466.463 bits (1199), Expect = 2.640e-157
Identity = 263/503 (52.29%), Postives = 335/503 (66.60%), Query Frame = 3 
Query:  231 NVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGK-FRVKYKKEKNPG-EMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            N + S   YDL+V+GGGSGGLA +KEAA +GK+V VLD+V+P+  GT WGLGGTCVNVGCIPKKLMH  A +R  ++ +   GW QI    Q    +W IM   V NY+ SLN+ +RVSL +N V+Y N   +F +  TI +T+S+G EK   A+ F+IA G RPRY  IPG K+Y ITSDDLF L   PGKTLVVG SYVALECAGFL   G D TVMVRSI LRGFD+QMA M+ E+ME E  +KFI    P  I + E G   R+K   + + G E ++ Y+T+L AIGRD CT ++ L +  V ++E T KI         D E+T  P IYAIGDVL+D +ELTPVAI+AG+LLARRL+ + T + +Y  +PTTVFTPLEY   G++EE AI +  ++N EVYH +F PLE  +       CY K+IC++    RVVG H+L  NAGE+ QGFA AIK G+T  QL NT+GIHP  AE    + +TKRS  +   +GC
Sbjct:   96 NPDRSGYDYDLIVIGGGSGGLAASKEAANYGKKVLVLDFVTPTPLGTKWGLGGTCVNVGCIPKKLMHQAALLRQALKDSQKYGW-QIEDNIQH---NWEIMTDSVLNYIGSLNFNYRVSLMQNNVKYENGYGEFVEPHTIKSTNSRGKEKYFTAEKFLIATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQQMANMIGEYME-EHGVKFIKQCVPTKIEQIEAGTPGRLKVTSQASDGAETTEEYNTVLLAIGRDACTRNIGLEIPGVKINEKTGKIPVN------DEEQTNVPYIYAIGDVLQDKLELTPVAIQAGRLLARRLYGDSTVKCDYVNVPTTVFTPLEYGACGLSEEHAIRQYEEENIEVYHSYFWPLEWTVPARDNNKCYAKIICNLKDKGRVVGFHVLSPNAGEITQGFAVAIKCGLTKDQLDNTIGIHPVCAEIFTTLTVTKRSGGNILQSGC 587
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Xenopus
Match: dpep1 (dipeptidase 1 [Source:Xenbase;Acc:XB-GENE-6043566])

HSP 1 Score: 458.759 bits (1179), Expect = 1.276e-155
Identity = 256/494 (51.82%), Postives = 323/494 (65.38%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDL+V+GGGSGGLACAK+AA FGK+VAV DYV PS RGT WG+GGTCVNVGCIPKKLMH  A +   ++ A   GW+     P  +  +W  MA  VQNYVKSLNWGHR+ L++ KV+Y N KA F D   I      G E  + A+N VIA GGRP+YP  +PGA +YGITSDDLFWLK+SPGKTLVVG SYV+LECAGFL   G DT  MVRSIPLRGFD+QMA +V ++ME     KF++   P ++ + + GK  V +K  ++  E +D+YDT+++A+GR   T  LNL  V V V   T KI   +       E T+ P+IYAIGD+ +   ELTP AI AGKLLA RLF+     M+Y+ + + VF     +                  +V+H F+KPLE I++      CY+K+IC     +R++GLH  G NAGEV+QGFA  IK G T+ QL  TVGIHPT AEEV K+HITKRS +DP +TGC
Sbjct:   20 YDLLVIGGGSGGLACAKQAAQFGKKVAVFDYVEPSPRGTKWGIGGTCVNVGCIPKKLMHQAALIGSTLKDAPHYGWDT----PNEIQHNWGKMAKAVQNYVKSLNWGHRIQLQDKKVKYFNMKASFVDEHCIRGVTKAGKETLVTAENIVIATGGRPKYPTHVPGALEYGITSDDLFWLKESPGKTLVVGASYVSLECAGFLTGIGLDTAAMVRSIPLRGFDQQMAYLVTDYMEL-HGTKFLWKCTPSNVEKLKNGKLEVTWKNTESGKEGADIYDTVMWAVGRAAETQYLNLEKVGVDVKSDTGKIIVNAS------EATSVPHIYAIGDITEGRPELTPTAIAAGKLLASRLFSGSAELMDYDSV-SNVFHAFYNSIFSF--------------QVFHAFYKPLEFIVAERNGSQCYIKIICLRTQDQRILGLHFTGPNAGEVIQGFALGIKCGATYHQLMRTVGIHPTCAEEVTKLHITKRSGLDPTVTGC 487
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Xenopus
Match: nmt1 (N-myristoyltransferase 1 [Source:Xenbase;Acc:XB-GENE-953051])

HSP 1 Score: 457.603 bits (1176), Expect = 1.363e-154
Identity = 259/494 (52.43%), Postives = 329/494 (66.60%), Query Frame = 3 
Query:  231 NVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGK-FRVKYKKEKNPG-EMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRS 1703
            N + S   YDL+V+GGGSGGLA +KEAA +GK+V VLD+V+P+  GT WGLGGTCVNVGCIPKKLMH  A +R  ++ +   GW QI    Q    +W IM   V NY+ SLN+ +RVSL +N V+Y N   +F +  TI +T+S+G EK   A+ F+IA G RPRY  IPG K+Y ITSDDLF L   PGKTLVVG SYVALECAGFL   G D TVMVRSI LRGFD+QMA M+ E+ME E  +KFI    P  I + E G   R+K   + + G E ++ Y+T+L AIGRD CT ++ L +  V ++E T KI         D E+T  P IYAIGDVL+D +ELTPVAI+AG+LLARRL+ + T + +Y  +PTTVFTPLEY   G++EE AI +  ++N EVYH +F PLE  +       CY K+IC++    RVVG H+L  NAGE+ QGFA AIK G+T  QL NT+GIHP  AE      I+ +S
Sbjct:   40 NPDRSGYDYDLIVIGGGSGGLAASKEAANYGKKVLVLDFVTPTPLGTKWGLGGTCVNVGCIPKKLMHQAALLRQALKDSQKYGW-QIEDNIQH---NWEIMTDSVLNYIGSLNFNYRVSLMQNNVKYENGYGEFVEPHTIKSTNSRGKEKYFTAEKFLIATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQQMANMIGEYME-EHGVKFIKQCVPTKIEQIEAGTPGRLKVTSQASDGAETTEEYNTVLLAIGRDACTRNIGLEIPGVKINEKTGKIPVN------DEEQTNVPYIYAIGDVLQDKLELTPVAIQAGRLLARRLYGDSTVKCDYVNVPTTVFTPLEYGACGLSEEHAIRQYEEENIEVYHSYFWPLEWTVPARDNNKCYAKIICNLKDKGRVVGFHVLSPNAGEITQGFAVAIKCGLTKDQLDNTIGIHPVCAEVQTTSLISPKS 522
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Mouse
Match: Txnrd2 (thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI:1347023])

HSP 1 Score: 508.064 bits (1307), Expect = 1.926e-174
Identity = 274/516 (53.10%), Postives = 349/516 (67.64%), Query Frame = 3 
Query:  195 TRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            TR+   G +   +     + +DL+V+GGGSGGLACAKEAA  GK+VAV DYV PS RGT WGLGGTCVNVGCIPKKLMH  A +  +I  AH  GW       Q +  +W  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+   D  G    + A++ VIA GGRPRYP  + GA +YGITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTTVM+RSIPLRGFD+QM+ +V EHME     +F+ G  P  I +    + +V ++   +  E +  +DT+L+AIGR P T  LNL    +S +   +KI   ++      E T+ P+IYAIGDV +   ELTP AIKAGKLLA+RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+   G ++ EVYH ++KPLE  ++      CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+HI+KRS ++P +TGC G
Sbjct:   23 TRALTRGTRGAASAAGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAHHYGWEVA----QPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESH-GTQFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGISTNPKNQKIIVDAQ------EATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLEPTVTGCUG 527
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Mouse
Match: Txnrd2 (thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI:1347023])

HSP 1 Score: 508.064 bits (1307), Expect = 1.926e-174
Identity = 274/516 (53.10%), Postives = 349/516 (67.64%), Query Frame = 3 
Query:  195 TRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            TR+   G +   +     + +DL+V+GGGSGGLACAKEAA  GK+VAV DYV PS RGT WGLGGTCVNVGCIPKKLMH  A +  +I  AH  GW       Q +  +W  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+   D  G    + A++ VIA GGRPRYP  + GA +YGITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTTVM+RSIPLRGFD+QM+ +V EHME     +F+ G  P  I +    + +V ++   +  E +  +DT+L+AIGR P T  LNL    +S +   +KI   ++      E T+ P+IYAIGDV +   ELTP AIKAGKLLA+RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+   G ++ EVYH ++KPLE  ++      CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+HI+KRS ++P +TGC G
Sbjct:   23 TRALTRGTRGAASAAGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAHHYGWEVA----QPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESH-GTQFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGISTNPKNQKIIVDAQ------EATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLEPTVTGCUG 527
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Mouse
Match: Txnrd2 (thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI:1347023])

HSP 1 Score: 508.064 bits (1307), Expect = 1.926e-174
Identity = 274/516 (53.10%), Postives = 349/516 (67.64%), Query Frame = 3 
Query:  195 TRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            TR+   G +   +     + +DL+V+GGGSGGLACAKEAA  GK+VAV DYV PS RGT WGLGGTCVNVGCIPKKLMH  A +  +I  AH  GW       Q +  +W  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+   D  G    + A++ VIA GGRPRYP  + GA +YGITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTTVM+RSIPLRGFD+QM+ +V EHME     +F+ G  P  I +    + +V ++   +  E +  +DT+L+AIGR P T  LNL    +S +   +KI   ++      E T+ P+IYAIGDV +   ELTP AIKAGKLLA+RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+   G ++ EVYH ++KPLE  ++      CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+HI+KRS ++P +TGC G
Sbjct:   23 TRALTRGTRGAASAAGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAHHYGWEVA----QPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESH-GTQFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGISTNPKNQKIIVDAQ------EATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLEPTVTGCUG 527
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Mouse
Match: Txnrd2 (thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI:1347023])

HSP 1 Score: 508.064 bits (1307), Expect = 1.926e-174
Identity = 274/516 (53.10%), Postives = 349/516 (67.64%), Query Frame = 3 
Query:  195 TRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            TR+   G +   +     + +DL+V+GGGSGGLACAKEAA  GK+VAV DYV PS RGT WGLGGTCVNVGCIPKKLMH  A +  +I  AH  GW       Q +  +W  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+   D  G    + A++ VIA GGRPRYP  + GA +YGITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTTVM+RSIPLRGFD+QM+ +V EHME     +F+ G  P  I +    + +V ++   +  E +  +DT+L+AIGR P T  LNL    +S +   +KI   ++      E T+ P+IYAIGDV +   ELTP AIKAGKLLA+RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+   G ++ EVYH ++KPLE  ++      CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+HI+KRS ++P +TGC G
Sbjct:   23 TRALTRGTRGAASAAGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAHHYGWEVA----QPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESH-GTQFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGISTNPKNQKIIVDAQ------EATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLEPTVTGCUG 527
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Mouse
Match: Txnrd2 (thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI:1347023])

HSP 1 Score: 495.352 bits (1274), Expect = 1.452e-169
Identity = 268/514 (52.14%), Postives = 343/514 (66.73%), Query Frame = 3 
Query:  195 TRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            TR+   G +   +     + +DL+V+GGGSGGLACAKEAA  GK+VAV DYV PS RGT WGLGGTCVNVGCIPKKLMH  A +  +I  AH  GW       Q +  +W  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+   D  G    + A++ VIA GGRPRYP  + GA +YGITSDD+FWLK+SPGKT V     VALECAGFL   G DTTVM+RSIPLRGFD+QM+ +V EHME     +F+ G  P  I +    + +V ++   +  E +  +DT+L+AIGR P T  LNL    +S +   +KI   ++      E T+ P+IYAIGDV +   ELTP AIKAGKLLA+RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+   G ++ EVYH ++KPLE  ++      CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+HI+KRS ++P +TGC
Sbjct:   20 TRALTRGTRGAASAAGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAHHYGWEVA----QPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITSDDIFWLKESPGKTSVPAAEDVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESH-GTQFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGISTNPKNQKIIVDAQ------EATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLEPTVTGC 522
[Close]
BLAST of Thioredoxin reductase vs. UniProt/SwissProt
Match: sp|Q9JLT4|TRXR2_MOUSE (Thioredoxin reductase 2, mitochondrial OS=Mus musculus OX=10090 GN=Txnrd2 PE=1 SV=4)

HSP 1 Score: 508.834 bits (1309), Expect = 5.450e-174
Identity = 274/516 (53.10%), Postives = 349/516 (67.64%), Query Frame = 3 
Query:  195 TRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            TR+   G +   +     + +DL+V+GGGSGGLACAKEAA  GK+VAV DYV PS RGT WGLGGTCVNVGCIPKKLMH  A +  +I  AH  GW       Q +  +W  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+   D  G    + A++ VIA GGRPRYP  + GA +YGITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTTVM+RSIPLRGFD+QM+ +V EHME     +F+ G  P  I +    + +V ++   +  E +  +DT+L+AIGR P T  LNL    +S +   +KI   ++      E T+ P+IYAIGDV +   ELTP AIKAGKLLA+RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+   G ++ EVYH ++KPLE  ++      CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+HI+KRS ++P +TGC G
Sbjct:   20 TRALTRGTRGAASAAGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAHHYGWEVA----QPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHME-SHGTQFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGISTNPKNQKIIVDAQ------EATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLEPTVTGCUG 524
[Close]
BLAST of Thioredoxin reductase vs. UniProt/SwissProt
Match: sp|Q9NNW7|TRXR2_HUMAN (Thioredoxin reductase 2, mitochondrial OS=Homo sapiens OX=9606 GN=TXNRD2 PE=1 SV=3)

HSP 1 Score: 498.819 bits (1283), Expect = 3.636e-170
Identity = 271/496 (54.64%), Postives = 337/496 (67.94%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPD-IPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQ-RPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            YDL+VVGGGSGGLACAKEAA  G++VAV+DYV PS +GT WGLGGTCVNVGCIPKKLMH  A +  +I+ A + GW      P     DW  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F D  T+      G E  + A + +IA GGRPRYP  I GA +YGITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTT+M+RSIPLRGFD+QM+ MV EHM      +F+ G  P  +     G+ +V ++      E +  +DT+L+AIGR P T  LNL    V     T+KI   S+      E T+ P+IYAIGDV++   ELTP+AI AG+LL +RLF   +  M+Y+ +PTTVFTPLEY CVG++EEEA+ R G ++ EVYH  +KPLE    G     CY+KM+C     + V+GLH LG NAGEV QGFA  IK G ++ Q+  TVGIHPT +EEVVK+ I+KRS +DP +TGC G
Sbjct:   40 YDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPH----DWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASH-GTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSR------EATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCUG 524
[Close]
BLAST of Thioredoxin reductase vs. UniProt/SwissProt
Match: sp|Q9Z0J5|TRXR2_RAT (Thioredoxin reductase 2, mitochondrial OS=Rattus norvegicus OX=10116 GN=Txnrd2 PE=1 SV=3)

HSP 1 Score: 495.738 bits (1275), Expect = 6.754e-169
Identity = 268/496 (54.03%), Postives = 342/496 (68.95%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            +DL+V+GGGSGGLACAKEAA  G++VAV DYV PS RGT WGLGGTCVNVGCIPKKLMH  A +  +I  A   GW       Q +  +W  MA  VQN+VKSLNWGHRV L++ KV+Y N KA F +  T+   D  G   ++ AK+ VIA GGRP+YP  + GA ++GITSDD+FWLK+SPGKTLVVG SYVALECAGFL   G DTTVM+RS+PLRGFD+QMA +V EHME     +F+ G  P  I +    + +V ++   +  E    +DT+L+AIGR P T +LNL    V+ +   +KI   ++      E T+ P+IYAIGDV +   ELTP AIKAGKLLA+RLF   +  MNY+ +PTTVFTPLEY CVG++EEEA+   G ++ EVYH ++KPLE  ++      CY+KM+C     + V+GLH LG NAGEV QGFA  I+ G ++ Q+  TVGIHPT +EEVVK+HI+KRS +DP +TGC G
Sbjct:   42 FDLLVIGGGSGGLACAKEAAQLGRKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAQHYGWE----VAQPVQHNWKAMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVNEHTVHGVDKAGKVTQLSAKHIVIATGGRPKYPTQVKGALEHGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSVPLRGFDQQMASLVTEHME-SHGTRFLKGCVPSLIRKLPTNQLQVTWEDLASGKEDVGTFDTVLWAIGRVPETRNLNLEKAGVNTNPKNQKIIVDAQ------EATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMNYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHIEVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIQCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLDPTVTGCUG 526
[Close]
BLAST of Thioredoxin reductase vs. UniProt/SwissProt
Match: sp|Q9N2I8|TRXR2_BOVIN (Thioredoxin reductase 2, mitochondrial OS=Bos taurus OX=9913 GN=TXNRD2 PE=1 SV=2)

HSP 1 Score: 488.419 bits (1256), Expect = 3.262e-166
Identity = 267/498 (53.61%), Postives = 336/498 (67.47%), Query Frame = 3 
Query:  249 KIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPD-IPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC*G 1736
            + YDL+V+GGGSGGLACAKEAA  GK+VAVLDYV PS +GT WGLGGTCVNVGCIPKKLMH  A +  +I  A   GW  +   P S    W  +A  VQN+VKSLNWGHR+ L++ KV+Y N KA F D  T+      G E  + A++ VIA GGRPRYP  I GA +YGITSDDLFWLK+SPGKTLVVG SYVALECAG L   G DTTVM+RS+PLR FD+QMA +V EHM      + + G  P  + +    + RV +    +  + +  +DT+L+AIGR P T+ LNL    V  +  T KI   ++      E T+ P+IYAIGDV +   ELTP AI AG+LLA+RL    +  M+Y+ +PTTVFTPLEY CVG++EE A+ R G+++ EVYH F+KPLE  +       CY+KM+C     + V+GLH LG NAGEV+QGFA  IK G +++QL  TVGIHPT AEEV K+ I+KRS +DP +TGC G
Sbjct:   26 QCYDLLVIGGGSGGLACAKEAAQLGKKVAVLDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAPHYGWG-VAQAPHS----WATLADAVQNHVKSLNWGHRIQLQDRKVKYFNVKASFVDTHTVCGVSKGGEETLLSAEHIVIATGGRPRYPTHIEGALEYGITSDDLFWLKESPGKTLVVGASYVALECAGLLTGLGLDTTVMIRSVPLRAFDQQMASLVTEHMAGH-GTRILRGCAPEKVEKLPGQQLRVTWVDLTSDRKDAGTFDTVLWAIGRVPETASLNLEKAGVHTNPVTGKILVDAQ------ETTSVPHIYAIGDVAEGRPELTPTAIMAGRLLAQRLSGRTSDLMDYSSVPTTVFTPLEYGCVGLSEEAAVARHGEEHVEVYHAFYKPLEFTVPQRDASQCYIKMVCLREPPQLVLGLHFLGPNAGEVIQGFALGIKCGASYQQLMRTVGIHPTCAEEVAKLRISKRSGLDPTVTGCUG 511
[Close]
BLAST of Thioredoxin reductase vs. UniProt/SwissProt
Match: sp|P91938|TRXR1_DROME (Thioredoxin reductase 1, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Trxr-1 PE=1 SV=2)

HSP 1 Score: 472.626 bits (1215), Expect = 8.530e-159
Identity = 265/495 (53.54%), Postives = 331/495 (66.87%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSER-GTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWN-QINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDL+V+GGGS GLACAKEA L G +VA LD+V P+   GT WG+GGTCVNVGCIPKKLMH  + + + +  A   GWN    +KP     DW  +   VQN++KS+NW  RV LR+ KVEYIN    F D+ T+ A    G E+ I A+ FVIAVGGRPRYPDIPGA +YGITSDDLF L + PGKTLVVG  Y+ LECAGFL   G + TVMVRSI LRGFD+QMAE+VA  ME ER I F+    P+S+ + + GK  VKYK  +   E  DVYDT+L+AIGR     DLNL    V+V +   KI   S+      E T   NIYA+GD++    ELTPVA+ AG+LLARRL+   T +M+Y  + TTVFTPLEYACVG++EE+A+ + G    EV+H ++KP E  I     R CY+K + +    +RV GLH +G  AGEV+QGFAAA+K G+T   L NTVGIHPT+AEE  ++ ITKRS +DP    C
Sbjct:  115 YDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNVDEKIKP-----DWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLKSG-ERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASME-ERGIPFLRKTVPLSVEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQK--DKIPVDSQ------EATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSGLDPTPASC 594
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BLAST of Thioredoxin reductase vs. TrEMBL
Match: A0A068ASV4 (Thioredoxin reductase OS=Dugesia japonica OX=6161 GN=TrxR PE=2 SV=1)

HSP 1 Score: 862.448 bits (2227), Expect = 0.000e+0
Identity = 420/527 (79.70%), Postives = 479/527 (90.89%), Query Frame = 3 
Query:  153 MRFCRYAIIVTYSATRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLS-NTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            M+  RYAII+TYSA RSF++G+KMN N +NS+KIYDLVV+GGGSGGLACAKEAA+FGK+VAVLDYV P+ + TSWGLGGTCVNVGCIPKKLMHHI+QMRD+IE+AH+AGW Q++VKP+SL IDWP MA+ VQNYVKSLNWGHRV+LRENK+EYINAKAKFKD +TI ATD KG EKEIKAKNFVIAVGGRP+YPDIPGAK++GITSDDLFWLK +PGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSI LRGFDRQMAEMV EHMEKE+KIKFIYGAEP+ +I+ + GK+RVK+KKEKNPGEMSD++DT+LFAIGRDPCT +LNLS  NVSVD  TKKI SGS S   D+EKT+APNIYAIGDVL+ GVELTPVAIKAGKLLARRLF+ ET QMNY++I TTVFTPLEYACVGMTEEEA  +LG+ N EVYHC+FKPLEI++MG Q+ CYMKMICDI  SE+VVGLHILG+NAGE+LQGFAAAIK GIT+ Q+  NT+GIHPTSAEEVVK+HITKRS++DPHLTGC
Sbjct:    1 MKLGRYAIIITYSAVRSFSTGLKMNYNASNSAKIYDLVVIGGGSGGLACAKEAAIFGKEVAVLDYVVPTLKSTSWGLGGTCVNVGCIPKKLMHHISQMRDIIENAHEAGWKQVSVKPESLQIDWPTMATRVQNYVKSLNWGHRVALRENKIEYINAKAKFKDGETIVATDIKGGEKEIKAKNFVIAVGGRPKYPDIPGAKEFGITSDDLFWLKNTPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIALRGFDRQMAEMVTEHMEKEKKIKFIYGAEPIEVIQGDSGKYRVKWKKEKNPGEMSDLFDTVLFAIGRDPCTLELNLSAANVSVDPNTKKILSGSNSKTVDMEKTSAPNIYAIGDVLQGGVELTPVAIKAGKLLARRLFHKETAQMNYDLIATTVFTPLEYACVGMTEEEASCKLGENNVEVYHCYFKPLEIVAMGQQQSCYMKMICDINKSEKVVGLHILGLNAGEILQGFAAAIKHGITYSQICLNTIGIHPTSAEEVVKLHITKRSNIDPHLTGC 527
[Close]
BLAST of Thioredoxin reductase vs. TrEMBL
Match: A0A1S3JWR9 (thioredoxin reductase 2, mitochondrial OS=Lingula unguis OX=7574 GN=LOC106176776 PE=3 SV=1)

HSP 1 Score: 538.495 bits (1386), Expect = 0.000e+0
Identity = 284/521 (54.51%), Postives = 368/521 (70.63%), Query Frame = 3 
Query:  192 ATRSFAS--GVK---MNCNVNNS--SKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            ++  FAS  GV+     C  +NS  +K YDLVVVGGGSGGLAC+KEAA +GK VAVLDYV PS +GT WGLGGTCVNVGCIPKKLMH  A + + ++ A   GW    V    +  +W  M+S VQNYV+SLNWGHRV L+   VEY+NAK  F D  T+ ATD+KG +K I A NFV+AVGGRP+Y +IPGA +  I+SDD+FWLK  PGKT+V+G SYVALECAGFL   G DT++M+RSIPLRGFD+QMA +V +HM        ++   P S+ +   GK +V +K  +     SD+Y+T+L A+GR P T+ + L    V +   + KI      +  DLE+++ P+IY IGD+L+   ELTPVAIKAGKLLA RL+ N T QM+Y+ +PTTVFTPLEY CVG++EEEA+++ G+ N EVYH F+KPL+  ++      CY+KMICD    ++V GLH LG +AGEVLQGFA AI+  +T + + +T+GIHPTSAEEVVK+HITKRS +DP +TGC
Sbjct:   29 SSHKFASFKGVQRLLTRCKSDNSIPTKKYDLVVVGGGSGGLACSKEAATYGKHVAVLDYVEPSPQGTKWGLGGTCVNVGCIPKKLMHQAALLGEAVQDARKYGWT---VPENGIHNNWETMSSAVQNYVRSLNWGHRVQLQSKNVEYLNAKGYFLDNHTLEATDAKGRKKRIVADNFVVAVGGRPKYTEIPGALECAISSDDIFWLKNKPGKTMVIGASYVALECAGFLTGLGFDTSLMIRSIPLRGFDQQMAHLVTDHM-ASHGTNMLWKCVPESMEKLSDGKIKVTWKNTETVEAGSDIYETVLMAVGRAPETTKIGLDNTEVQLHASSGKILG---EHGGDLERSSVPHIYGIGDILEGRPELTPVAIKAGKLLAHRLYGNSTVQMDYDKVPTTVFTPLEYGCVGLSEEEALDKYGEDNLEVYHAFYKPLQYSVAERDASQCYIKMICDKEGDQKVHGLHFLGPHAGEVLQGFAVAIRCNLTREIMDSTLGIHPTSAEEVVKMHITKRSGLDPTVTGC 542
[Close]
BLAST of Thioredoxin reductase vs. TrEMBL
Match: V4AUG6 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_159432 PE=3 SV=1)

HSP 1 Score: 525.783 bits (1353), Expect = 9.091e-179
Identity = 273/496 (55.04%), Postives = 351/496 (70.77%), Query Frame = 3 
Query:  252 IYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQR---PCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            +YD VV+GGGSGGLACAKEA+  G++VAVLD+V PS +GT WGLGGTCVNVGCIPKKL+H  A +   I+ A   GWN     P  +   W  M   VQNYV+SLNWGHRV L++  VEYINA     D  T+   D KG E+ +   N VIAVGGRPR PDIPGA QY ITSDDLFW+ K PGKTLVVG SY+ALEC GFL   G DTTVMVRSI LRGFD+QMA  + ++M      KF+    P  I +   G++ V Y  +KN    +D++DT+L A+GR+  T  +NL  + V +D  +KK+  G K+N    E+++  NIYAIGDVL +  ELTPVAIKAGKLLA+RLFNN+T  M+Y  +PTTVFTP+EY CVG++EE A+ + G++N E+YH F+KPLE  +M  +R    CY+K+IC+      V+GLH+LG NAGEV+QGF+ A++ GI+++ + NTVGIHPT AEE+VK++I+KRS +DP +TGC
Sbjct:    1 MYDFVVIGGGSGGLACAKEASQLGQKVAVLDFVKPSTQGTKWGLGGTCVNVGCIPKKLIHQAALLGHSIQDAKYYGWN----IPSDITHSWESMCDNVQNYVRSLNWGHRVQLKDKNVEYINAVGTLVDKHTVKTVDGKGKERLLSTDNIVIAVGGRPRLPDIPGALQYSITSDDLFWMTKPPGKTLVVGASYIALECGGFLTGLGFDTTVMVRSILLRGFDQQMANHIGDYMSN-NGTKFLRECIPTEIKKTSTGQYSVTY-SDKNKNTHNDMFDTVLMAVGRNAVTGSVNLENIGVELDTTSKKVIGGYKNNS---ERSSIDNIYAIGDVLYNKPELTPVAIKAGKLLAQRLFNNQTQAMDYQNVPTTVFTPIEYGCVGLSEESAVEKFGEENLEIYHAFYKPLE-YAMVTERDVSQCYIKLICERQSPHTVLGLHLLGPNAGEVIQGFSVAVRNGISYEGIINTVGIHPTCAEEIVKLNISKRSGLDPTVTGC 486
[Close]
BLAST of Thioredoxin reductase vs. TrEMBL
Match: Q7T0L5 (Txnrd2 protein OS=Xenopus laevis OX=8355 GN=txnrd2 PE=2 SV=1)

HSP 1 Score: 516.924 bits (1330), Expect = 4.186e-175
Identity = 277/494 (56.07%), Postives = 343/494 (69.43%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDL+V+GGGSGGLACAK+AA FGK+VAV DYV PS RGT WG+GGTCVNVGCIPKKLMH  A +   ++ A   GW      P  +  DW  MA  VQNYVKSLNWGHR+ L++ KV+Y N KA F D   I      G E  + A+N VIA GGRP+YP  +PGA +YGITSDDLFWLK+SPGKTLVVG SYV+LECAGFL   G +TT MVRSIPLRGFD+QMA +VA++ME     KF++   P  + + + GK +V +K  ++  E  D+YDT+++A+GR   T  LNL  V V +   T KI   +       E T+ P+IYAIGD+ +   ELTP AI AGKLLA RLF+     M+Y+ +PTTVFTPLEY CVG++EEEA  R GD N EV+H F+KPLE  ++      CY+K+IC   H +R++GLH+ G NAGEV+QGFA  IK G T+ QL  TVGIHPT AEEV K+HITKRS +DP +TGC
Sbjct:   20 YDLLVIGGGSGGLACAKQAAQFGKKVAVFDYVEPSPRGTKWGIGGTCVNVGCIPKKLMHQAALIGSTMKDAPHYGWGT----PYEIQHDWGKMAGAVQNYVKSLNWGHRIQLQDKKVKYFNLKANFVDEHCIRGVTKAGKETLVTAQNIVIATGGRPKYPTHVPGALEYGITSDDLFWLKESPGKTLVVGASYVSLECAGFLTGIGLNTTAMVRSIPLRGFDQQMAYLVADYME-SHGTKFLWKCTPSHVEKLKNGKLQVTWKNTQSGKEGVDIYDTVMWAVGRAAETQYLNLEKVGVKIKPETGKIIVDAS------EATSVPHIYAIGDITEGRPELTPTAIAAGKLLAIRLFSGSAELMDYDSVPTTVFTPLEYGCVGISEEEAKERYGDDNIEVFHAFYKPLEFTVAERDASQCYIKIICLRKHDQRILGLHLTGPNAGEVIQGFALGIKCGATYPQLMCTVGIHPTCAEEVTKLHITKRSGLDPTVTGC 502
[Close]
BLAST of Thioredoxin reductase vs. TrEMBL
Match: W4YIA6 (Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1)

HSP 1 Score: 515.768 bits (1327), Expect = 7.597e-175
Identity = 266/498 (53.41%), Postives = 347/498 (69.68%), Query Frame = 3 
Query:  243 SSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPD-IPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            SS  YDL V+GGGSGGLACAKEAA F K+V VLDYV PS +GT WGLGGTCVNVGCIPKKL+HH + +R+ +  A   GW      P  + + W  +   +Q +VKSLNWGHRV L++  VEY+N K  F D  T+      G E +  A N V+A GGRP+YPD +PGA +YGITSDD+F LK  PG++LV+GGSYVALECAGFLH  G  TTVMVRSI LRGFD+QM+ +VA+HME    I+F++   P S+ + + G   V+++ ++   E    +DT++FA+GR+P T+ L L    V + EG K + S         E+++ P+I+AIGD+L+ G+ELTPVAI+ GKLLA+RLF   T  MNY  + TTVFTPLEY+CVG++EE A  R G+ + EVYH F+KPLE ++       CY+K IC     +R++GLHI G  AGE++QGFA A+K G T++ LS+T+GIHPT AEEVVKIHITKRS +DP +TGC
Sbjct:    6 SSYDYDLAVIGGGSGGLACAKEAAGFDKKVIVLDYVDPSPQGTKWGLGGTCVNVGCIPKKLLHHASLLRESMHDAKHYGWQ----VPDDIGLSWSTLIGGIQGHVKSLNWGHRVQLQDKNVEYVNGKGSFIDEHTVKVKMKDGKETQFSAANIVLATGGRPKYPDKVPGAMEYGITSDDIFSLKTPPGRSLVIGGSYVALECAGFLHGLGFPTTVMVRSICLRGFDQQMSRLVADHMEAS-GIQFLWQQVPESVAKNQNGSLNVRWRSDQGQ-EGHGEFDTVMFAVGREPETAQLGLDNTGVQLSEGGKVMGSN--------EQSSVPHIHAIGDILESGIELTPVAIRTGKLLAQRLFGQGTEHMNYEQVATTVFTPLEYSCVGLSEETATERYGEDHIEVYHAFYKPLEYVVPNKPAEQCYIKAICLRDGDQRILGLHITGPGAGEIMQGFALAVKMGATYQHLSSTIGIHPTCAEEVVKIHITKRSGLDPMVTGC 489
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Cavefish
Match: txnrd3 (thioredoxin reductase 1, cytoplasmic [Source:NCBI gene;Acc:103047502])

HSP 1 Score: 442.195 bits (1136), Expect = 2.414e-149
Identity = 247/487 (50.72%), Postives = 307/487 (63.04%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ---GKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRS 1703
            YDL+V+GGGSGGLAC+KEAA  GK+V VLDYV P+ +GT+WGLGGTCVNVGCIPKKLMH  A M   ++ A   GW       + +  +W  M + V NY+ SLNWG+RVSLR+  V Y+N+ A+F +   I AT+ +G E    A  FV+A G RPRY  IPG K+Y ITSDDLF L   PGKTLV+G SYVALEC GFL   G D T+MVRSI LRGFD+ MA    +HME    +KF+    PV + E E    G+ +V  K  +        Y+T+L A+GRD CT  + L         G K      K    D E+T  P+IYAIGD+L+   ELTPVAI+AGKLLARRL+   + + +Y  +PTTVFTPLEY   G  EE A+   G +N EVYH  F PLE  +       CY K+IC+     RV+G H LG NAGEV QGF AA+K G+T +QL NT+GIHPT AE    + +TKRS
Sbjct:   13 YDLIVIGGGSGGLACSKEAANLGKKVMVLDYVVPTPKGTTWGLGGTCVNVGCIPKKLMHQTALMGTALQDARKFGWEF----SEQVSHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNSYAEFVEPHKIKATNRRGKETFHTAAKFVLATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMANRAGDHMET-HGVKFLRKFVPVKVEELEAGTPGRLKVTAKSTETDEIFEGEYNTVLIAVGRDACTEKIGLDQA------GVKVNPKNGKIPVNDEEQTNIPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGASLKCDYVNVPTTVFTPLEYGSCGHPEERAVELYGQENLEVYHSLFWPLEYTVPNRDNNRCYAKIICNKLDDNRVIGFHYLGPNAGEVTQGFGAAMKCGVTKEQLDNTIGIHPTCAEIFTTMEVTKRS 488
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Cavefish
Match: txnrd3 (thioredoxin reductase 1, cytoplasmic [Source:NCBI gene;Acc:103047502])

HSP 1 Score: 445.277 bits (1144), Expect = 4.564e-149
Identity = 250/496 (50.40%), Postives = 310/496 (62.50%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ---GKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDL+V+GGGSGGLAC+KEAA  GK+V VLDYV P+ +GT+WGLGGTCVNVGCIPKKLMH  A M   ++ A   GW       + +  +W  M + V NY+ SLNWG+RVSLR+  V Y+N+ A+F +   I AT+ +G E    A  FV+A G RPRY  IPG K+Y ITSDDLF L   PGKTLV+G SYVALEC GFL   G D T+MVRSI LRGFD+ MA    +HME    +KF+    PV + E E    G+ +V  K  +        Y+T+L A+GRD CT  + L         G K      K    D E+T  P+IYAIGD+L+   ELTPVAI+AGKLLARRL+   + + +Y  +PTTVFTPLEY   G  EE A+   G +N EVYH  F PLE  +       CY K+IC+     RV+G H LG NAGEV QGF AA+K G+T +QL NT+GIHPT AE    + +TKRS  D    GC
Sbjct:  116 YDLIVIGGGSGGLACSKEAANLGKKVMVLDYVVPTPKGTTWGLGGTCVNVGCIPKKLMHQTALMGTALQDARKFGWE----FSEQVSHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNSYAEFVEPHKIKATNRRGKETFHTAAKFVLATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMANRAGDHMET-HGVKFLRKFVPVKVEELEAGTPGRLKVTAKSTETDEIFEGEYNTVLIAVGRDACTEKIGLDQA------GVKVNPKNGKIPVNDEEQTNIPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGASLKCDYVNVPTTVFTPLEYGSCGHPEERAVELYGQENLEVYHSLFWPLEYTVPNRDNNRCYAKIICNKLDDNRVIGFHYLGPNAGEVTQGFGAAMKCGVTKEQLDNTIGIHPTCAEIFTTMEVTKRSGGDITQAGC 600
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Cavefish
Match: txnrd2.2 (thioredoxin reductase 2 [Source:NCBI gene;Acc:103037574])

HSP 1 Score: 413.305 bits (1061), Expect = 4.303e-139
Identity = 214/437 (48.97%), Postives = 290/437 (66.36%), Query Frame = 3 
Query:  426 MHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPD-IPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            MH  A +   ++ A   GW QI   PQ +  DW  +A  VQNYVKSLNWGHRV L++ KV+Y+N K    D  T+    S+G E  + A+N +IA GGRP+YP  +PGA ++GI+SDDLFWLK++PGKTLVVG SYV LECAGFL   G + TVMVRSI LRGFD+QM+ +V ++M+     +F +   P  + +   G  +V +   +   +  D ++++L+A+GR P T  LNL  V V +D  T+K+         D E+T+ PNIYAIGD+ +   ELTP AI AGKLLARRL    +  M+Y+ +PTTVFTPLEY CVG++EEEA  R G    EVYH F+KPLE  ++    R CY+K++C+    ++VVGLH  G NAGEV QGFA +++ G+++ QL ++VGIHPT AEE+ KI+ITKRS +D  +TGC
Sbjct:    1 MHQAALLGSAVKDAQKYGW-QI---PQPVSHDWATLAESVQNYVKSLNWGHRVQLQDRKVKYMNMKGSLVDDHTVRCLSSRGKEMTVTARNILIATGGRPKYPTHVPGALEFGISSDDLFWLKETPGKTLVVGASYVGLECAGFLTGIGLEATVMVRSIALRGFDQQMSRLVTDYMQG-YGTRFCWDCVPKKVEKLPSGLLQVTWTDSRTGQDHQDTFNSVLWAVGRAPETGTLNLQQVGVELDGDTRKVMVA------DDERTSVPNIYAIGDIAQGRPELTPTAIHAGKLLARRLAGLSSQLMDYSNVPTTVFTPLEYGCVGLSEEEAERRYGKDKVEVYHAFYKPLEFTVAERELRQCYIKVVCERDGDQKVVGLHFTGPNAGEVTQGFALSLRCGLSYAQLRDSVGIHPTCAEELTKIYITKRSGLDATVTGC 426
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Cavefish
Match: txnrd2.2 (thioredoxin reductase 2 [Source:NCBI gene;Acc:103037574])

HSP 1 Score: 413.305 bits (1061), Expect = 4.303e-139
Identity = 214/437 (48.97%), Postives = 290/437 (66.36%), Query Frame = 3 
Query:  426 MHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPD-IPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            MH  A +   ++ A   GW QI   PQ +  DW  +A  VQNYVKSLNWGHRV L++ KV+Y+N K    D  T+    S+G E  + A+N +IA GGRP+YP  +PGA ++GI+SDDLFWLK++PGKTLVVG SYV LECAGFL   G + TVMVRSI LRGFD+QM+ +V ++M+     +F +   P  + +   G  +V +   +   +  D ++++L+A+GR P T  LNL  V V +D  T+K+         D E+T+ PNIYAIGD+ +   ELTP AI AGKLLARRL    +  M+Y+ +PTTVFTPLEY CVG++EEEA  R G    EVYH F+KPLE  ++    R CY+K++C+    ++VVGLH  G NAGEV QGFA +++ G+++ QL ++VGIHPT AEE+ KI+ITKRS +D  +TGC
Sbjct:    1 MHQAALLGSAVKDAQKYGW-QI---PQPVSHDWATLAESVQNYVKSLNWGHRVQLQDRKVKYMNMKGSLVDDHTVRCLSSRGKEMTVTARNILIATGGRPKYPTHVPGALEFGISSDDLFWLKETPGKTLVVGASYVGLECAGFLTGIGLEATVMVRSIALRGFDQQMSRLVTDYMQG-YGTRFCWDCVPKKVEKLPSGLLQVTWTDSRTGQDHQDTFNSVLWAVGRAPETGTLNLQQVGVELDGDTRKVMVA------DDERTSVPNIYAIGDIAQGRPELTPTAIHAGKLLARRLAGLSSQLMDYSNVPTTVFTPLEYGCVGLSEEEAERRYGKDKVEVYHAFYKPLEFTVAERELRQCYIKVVCERDGDQKVVGLHFTGPNAGEVTQGFALSLRCGLSYAQLRDSVGIHPTCAEELTKIYITKRSGLDATVTGC 426
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Cavefish
Match: ENSAMXT00000055472.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002185.1:27093:32744:-1 gene:ENSAMXG00000036332.1 transcript:ENSAMXT00000055472.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 406.371 bits (1043), Expect = 1.308e-135
Identity = 237/493 (48.07%), Postives = 295/493 (59.84%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDL+V+GGGSGGLAC+K       +V VLDYV P+ +GT+WGLGGTCVNVGCIPKKLMH  A M   ++ A   GW       + +  +W  M + V NY+ SLNWG+RVSLR+  V Y+N+ A+F +   I AT+ +G E    A  FV+A G RPRY  IPG K+Y ITSDDLF L   PGKTLV+G SYVALEC GFL   G D T+MVRSI LRGFD+ MA    +HME    +KF+             G+ +V  K  +        Y+T+L A+GRD CT  + L         G K      K    D E+T  P+IYAIGD+L+   ELTPVAI+AGKLLARRL+   + + +Y  +PTTVFTPLEY              G +N EVYH  F PLE  +       CY K+IC+     RV+G H LG NAGEV QGF AA+K G+T +QL NT+GIHPT AE    + +TKRS  D    GC
Sbjct:   13 YDLIVIGGGSGGLACSK-------KVMVLDYVVPTPKGTTWGLGGTCVNVGCIPKKLMHQTALMGTALQDARKFGWEF----SEQVSHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNSYAEFVEPHKIKATNRRGKETFHTAAKFVLATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMANRAGDHMET-HGVKFLRKF----CSSGTPGRLKVTAKSTETDEIFEGEYNTVLIAVGRDACTEKIGLDQA------GVKVNPKNGKIPVNDEEQTNIPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGASLKCDYVNVPTTVFTPLEYEL-----------YGQENLEVYHSLFWPLEYTVPNRDNNRCYAKIICNKLDDNRVIGFHYLGPNAGEVTQGFGAAMKCGVTKEQLDNTIGIHPTCAEIFTTMEVTKRSGGDITQAGC 472
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Sea Lamprey
Match: txnrd3 (thioredoxin reductase 3 [Source:ZFIN;Acc:ZDB-GENE-030327-3])

HSP 1 Score: 448.358 bits (1152), Expect = 1.200e-150
Identity = 248/492 (50.41%), Postives = 323/492 (65.65%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ---GKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPH 1718
            YDL+V+GGGSGGLA +KEAA  GK+V VLD+V P+  GTSWGLGGTCVNVGCIPKKLMH  A +   +  +   GW       Q +  +W  M   +QNY+ SLNWG+RV+LR++ V Y+NA   F DA  I AT+ +G E +  A+ F++A+G RPRY  IPG K++ ITSDDLF L   PGKTLVVG SYVALECAGFL   G D TVMVRSI LRGFD+QMAE+  ++MEK   +KFI    P  + + E    G+ +V  K  +        ++T+L A+GRD CTS++ L VV V VDE T K+         D+E+T  P++YAIGD+L+  +ELTP+AI+AG+LLA+RL+   T + +Y  + TTVFTPLEY C G++EE AI  LG  N EV+H  F PLE  ++ G    CY K++C+    +RVVG H+LG NAGE+ QGF  A+K G+T  QL +T+GIHPT AE         R+H   H
Sbjct:  129 YDLIVIGGGSGGLAASKEAAKLGKKVMVLDFVQPTPLGTSWGLGGTCVNVGCIPKKLMHQAALLGHALSDSRKFGWEY----DQQVTHNWSTMKEAIQNYIGSLNWGYRVALRDHAVSYVNAFGTFTDAHAIKATNKRGKETQHTAETFILAMGERPRYLGIPGDKEFCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQQMAELAGDYMEK-HGVKFIRQFVPTKVEQLEAGTPGRLKVHAKATEGSELYEGEFNTVLIAVGRDACTSNIGLDVVGVKVDERTGKVPVN------DVEQTNVPHVYAIGDILQGKLELTPIAIQAGRLLAQRLYGGGTTKCDYVNVCTTVFTPLEYGCCGLSEERAIELLGGDNIEVFHSNFWPLEWTVAGGDNNSCYAKILCNKADKDRVVGFHVLGPNAGEITQGFGVAMKCGLTKAQLDDTIGIHPTCAE-------VGRAHTATH 602
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Sea Lamprey
Match: dldh (dihydrolipoamide dehydrogenase [Source:ZFIN;Acc:ZDB-GENE-040120-4])

HSP 1 Score: 105.531 bits (262), Expect = 2.784e-24
Identity = 106/442 (23.98%), Postives = 191/442 (43.21%), Query Frame = 3 
Query:  381 LGGTCVNVGCIPKKLM------HHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGR-PRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVM--VRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFK-PLEIISMGLQRPCYMKMICDIGHSE--RVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAE 1670
            LGGTC+NVGCIP K +      +H+A  +D         +    ++ Q L ++   M       VK+L  G     ++NKV ++           +TA  + G ++ I  KN +IA G     +  I   ++  ++S     LK+ P K +V+G   + +E        G + T +  +  +   G D ++++     ++K+  +KF    + ++      GK  V+ +  K     +   D +L  +GR P T         + ++E    + +  +    +  +T+ PNIYAIGD +  G  L   A   G +    +       ++YN +P+ ++T  E A +G  EE+       K   V +   K P    S          ++  + H E  R++G HILG  AGE++   A A++ G + + ++     HPT +E
Sbjct:   75 LGGTCLNVGCIPSKALLNNSYFYHLAHGKD---------FASRGIEIQGLKLNLEKMMEQKSGAVKALTGGIAHLFKQNKVTHVKGHGMITGKNQVTAACADGSQQVINTKNILIATGSEVTPFQGIEVDEETVVSSTGALSLKQVPEKLVVIGAGVIGVELGSVWQRLGAEVTAVEFLGHVGGAGIDMEISKNFQRILQKQ-GMKFKLSTKVMAASRRADGKIDVQTEPAKGGAADTLTCDVLLVCVGRRPFT-------AGLGLEELGIALDNRGRVPINNRFQTSIPNIYAIGDAVA-GPMLAHKAEDEGIICVEGMAGGAV-HIDYNCVPSVIYTHPEVAWIGKNEEQL------KEEGVPYKIGKFPFAANSRAKTNADTDGLVKILAHKETDRMLGAHILGSGAGEMINEAALAMEYGASCEDVARVCHAHPTVSE 491
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Yeast
Match: GLR1 (Cytosolic and mitochondrial glutathione oxidoreductase; converts oxidized glutathione to reduced glutathione; cytosolic Glr1p is the main determinant of the glutathione redox state of the mitochondrial intermembrane space; mitochondrial Glr1p has a role in resistance to hyperoxia; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006012])

HSP 1 Score: 238.039 bits (606), Expect = 1.131e-71
Identity = 163/505 (32.28%), Postives = 269/505 (53.27%), Query Frame = 3 
Query:  189 SATRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAG-WNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPD-IPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVR-SIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNE---TGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKI 1685
            SAT+     +++   ++ ++K YD +V+GGGSGG+A A+ AA +G +  +++         +  LGGTCVNVGC+PKK+M + + +   +  A++ G +  + +  + L  +WP        YV  LN  ++ +L + KV+ +   A+F     +         +   A + ++A GG+  +P+ IPG  + G  SD  F L++ P K +VVG  Y+ +E AG  H  G +T +++R    LR FD  +   + +H  KE     I   +   I++ E+     K K   N  +  D  D +++ IGR       + +V          K+ S  +    + + T  PNIY++GDV+   VELTPVAI AG+ L+ RLF  E     +++Y  +P+ +F+  E   +G++E+EAI + G +N +VY+  F  +    +  + P   K++C  G +E+VVGLHI+G ++ E+LQGF  AIK G T     N V IHPTSAEE+V +
Sbjct:    3 SATKQTFRSLQIRT-MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGF-ELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG----INVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGI--------KLNSHDQIIADEYQNTNVPNIYSLGDVVGK-VELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVC-AGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482
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BLAST of Thioredoxin reductase vs. Ensembl Yeast
Match: LPD1 (Dihydrolipoamide dehydrogenase; the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes; PDH complex is concentrated in spots within the mitochondrial matrix, often near the ERMES complex and near peroxisomes; LPD1 has a paralog, IRC15, that arose from the whole genome duplication [Source:SGD;Acc:S000001876])

HSP 1 Score: 87.4261 bits (215), Expect = 1.149e-18
Identity = 132/511 (25.83%), Postives = 224/511 (43.84%), Query Frame = 3 
Query:  198 RSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKL----------MHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIK------AKNFVIAVGGR-PRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRG--FDRQMAEMVAEHMEKERKIKFIYGAEPVSIIE-AEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAE 1670
            R+F+S V+    +N S   +D+V++GGG  G   A +AA  G   A ++     +RG    LGGTC+NVGCIP K           MH  AQ R  I+   D   N  N +                + VK L  G  +  ++NKV Y      F+D   I  T   G+E  +K       KN ++A G     +P I   ++  ++S     LK+ P +  ++GG  + LE        G   TV V   P  G   D ++A+   + ++K+  + F    + +S     ++    +  +  K   + +   + +L A+GR P  + L    + + VD+  + +         D   +  P+I  +GDV   G  L   A + G + A  +     G +NYN IP+ +++  E A VG TEE+   +    + ++    F              ++K++ D   +ER++G HI+G NAGE++     A++ G + + ++     HPT +E
Sbjct:   12 RAFSSTVR-TLTINKS---HDVVIIGGGPAGYVAAIKAAQLGFNTACVE-----KRGK---LGGTCLNVGCIPSKALLNNSHLFHQMHTEAQKRG-IDVNGDIKINVANFQKAK------------DDAVKQLTGGIELLFKKNKVTYYKGNGSFEDETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTGALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTV-VEFQPQIGASMDGEVAKATQKFLKKQ-GLDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDKRGRLVID-------DQFNSKFPHIKVVGDVTF-GPMLAHKAEEEG-IAAVEMLKTGHGHVNYNNIPSVMYSHPEVAWVGKTEEQL--KEAGIDYKIGKFPFAANSRAKTNQDTEGFVKILID-SKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSE 483
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BLAST of Thioredoxin reductase vs. Ensembl Nematostella
Match: EDO38228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDH7])

HSP 1 Score: 469.159 bits (1206), Expect = 7.562e-159
Identity = 256/501 (51.10%), Postives = 339/501 (67.66%), Query Frame = 3 
Query:  240 NSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ---GKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            ++S  YDL+V+GGGSGGLACAKEAA  G++VAVLD+V P+ +GT+WGLGGTCVNVGCIPKKLMH  A + + ++ A   GW + + K +    +W  +   VQN++ SLNWG+RV LRE  V Y NA  +F D  TI ATD +G E  + A+ FV+A+G RPRYP+IPGAK+YGITSDDLF L   PG T+++G SYV+LECAGFL A G D TV+VRSI LRGFD+QMAE     ME    +KF   A P  + + E+   GK RV YK E       D  +T++FAIGRD CT+ + L  V V ++   +K+ +G      D E+++ PNIYAIGD+L   +ELTPVAI+AG+LL+RRL+ N+T   +Y  + TTVFTPLEY  +G +EE+AI + G +N EVYH  F+PLE  ++   +  CY K+IC+   SERVVG H+LG NAGE+ QG+A A K G T +   +T+GIHPT +E    + +TKRS      +GC
Sbjct:  105 SASYEYDLIVIGGGSGGLACAKEAAQLGRKVAVLDFVKPTPKGTTWGLGGTCVNVGCIPKKLMHQAALLGEALKDARLYGW-EFDEKVKH---NWESLREGVQNHIGSLNWGYRVQLREKSVTYKNAFGEFIDNHTIKATDKRGTETIMTAETFVLAMGLRPRYPNIPGAKEYGITSDDLFSLPYCPGTTVLIGASYVSLECAGFLAAMGLDVTVVVRSILLRGFDQQMAEKAGSFMET-HGVKFKRPAVPTKVEQLEEGSPGKLRVHYKLEGGEEGHLDC-NTVVFAIGRDACTTGIGLEKVGVKLNPKNQKVIAG------DNEQSSVPNIYAIGDILDGKLELTPVAIQAGRLLSRRLYRNDTKLCDYINVATTVFTPLEYGAIGYSEEDAIQKFGQENVEVYHTLFQPLEYTVAQRSKDDCYAKLICNKADSERVVGFHVLGPNAGEITQGYAVAFKCGATKEHFDDTIGIHPTCSETFTLLDVTKRSGASIVSSGC 593
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BLAST of Thioredoxin reductase vs. Ensembl Nematostella
Match: EDO46553 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPR5])

HSP 1 Score: 392.119 bits (1006), Expect = 7.624e-131
Identity = 239/495 (48.28%), Postives = 308/495 (62.22%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIIS-MGLQRPCYMKMICDIGHSERVVGLH-ILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDLVV+GGGSGGLAC+KEAA  GK+VAVLD+V+PS +G++WG+GGTCVNVGCIPKKLMHH + + D I+ A   GW   +     +  DW  + + VQNY+KSLNWG+RV L +  V YI   A F D  TI A    G E+ + ++  VIAVGGRPR+P D+PGAK+Y ITSDDLF L+K PGKTLV+G SYVALECAGFL  FG +T++M+RSIPLRGFD+QMA +V E+M +    +FI    PVS+ +   GK  V++    +     + +DT+L AIGRDP T+ L L         G +   SG      + E+T+A NIYA+GDVL+D  ELTPVAI AGKLLARRLF   T QM+Y+ +       L +         +IN+              P+ + S M L  P +    C  G       L+ +LGM             + G+T + LS+TVGIHPT AEEVVK+HITKRS  DP +TGC
Sbjct:    1 YDLVVIGGGSGGLACSKEAASLGKKVAVLDFVAPSPQGSTWGIGGTCVNVGCIPKKLMHHASLLGDGIKDAKKYGWQLSD----QMTFDWGNLVTGVQNYIKSLNWGYRVQLHDKSVRYIPGMASFVDRHTIKAVLKSGKEELLTSEKVVIAVGGRPRFPSDVPGAKEYCITSDDLFSLQKPPGKTLVIGASYVALECAGFLAGFGYNTSLMMRSIPLRGFDQQMASLVTEYMSRH-GTRFINQCVPVSVDKRPDGKLHVQWTNPSSGERGEEEFDTVLMAIGRDPSTAALELDKA------GVQVDKSGFIIG-MENEQTSAKNIYALGDVLQDRPELTPVAIMAGKLLARRLFAGSTIQMDYDNVRILSLRRLLH---------SINKAAKAEEHA------PVRLYSMMSLLTPYWG---CTTGDLYTRPSLNPLLGMY-----------YRCGLTMRMLSSTVGIHPTCAEEVVKLHITKRSGEDPTVTGC 454
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Nematostella
Match: EDO43495 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYC0])

HSP 1 Score: 226.868 bits (577), Expect = 2.968e-67
Identity = 170/483 (35.20%), Postives = 258/483 (53.42%), Query Frame = 3 
Query:  249 KIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVR-SIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDV--YDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETG-QMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKI 1685
            K YD VV+GGGSGG+A A+ AA FG +  V+++           LGGTCVNVGC+PKK+M + A   + +    D G++ I  K       W  +      +V  LN  +  +L +  V+++   A+F     +   D     +    K+ +IA GG P  P IPG  ++GITSD  F L+  P K  VVG  Y+A+E AG L+A G   ++++R +  +R FD  ++ M+ E + K+  I           +  +     +     KN  E  D+  YD +L+A+GR+P T++L L  + + +D+G   I         + + TT  N+YA+GDV    + LTPVAI AG+ LA RLF+ +T  +++Y  IPT VF+      +G+TEE+A  + G    ++Y   F  +       +   +MK+I  +   E+V+GLHILG+ A E+LQGFA AIK G T     N V IHPTS+EE+V +
Sbjct:    5 KAYDYVVIGGGSGGIASARRAAEFGVKAVVIEHAR---------LGGTCVNVGCVPKKIMFNAAMCAETLPYYKDYGFDVILNK-----FTWKNIKEKRDAHVSKLNTIYENNLGKAHVDFVAGHAQFTPDGNVKVGD-----QLFSGKHILIATGGVPSLPSIPGF-EHGITSDGFFELEDLPKKVAVVGAGYIAVELAGILNALGSRVSLLIRYNNVIRNFDSMLSGMLTEEI-KDSGIDLCTNT-TTEQVSKDSNTGLLTLHTLKNKTEKVDLSGYDCLLWAMGRNPNTNNLGLEHMGIEMDKGGHIIVD-------EFQNTTRKNVYALGDVCGKAL-LTPVAISAGRKLAHRLFDGQTNLKLDYVNIPTVVFSHPTIGTIGLTEEQAAQQYGKDKLKIYKSTFVNMYYAVTDKKHKTHMKLITLLP-EEKVIGLHILGLGADEMLQGFAVAIKMGATKADFDNAVAIHPTSSEELVTM 456
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Nematostella
Match: EDO46554 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPR6])

HSP 1 Score: 192.586 bits (488), Expect = 5.523e-58
Identity = 98/163 (60.12%), Postives = 124/163 (76.07%), Query Frame = 3 
Query: 1245 VLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            +L+D  ELTPVAI AGKLLARRLF   T QM+Y+ I TTVFTPLEY+ VG++EE+AI + G++N EVYH F+KPLE  ++   +   Y+K +C     + V+GLH LG NAGEV+QGFA AI+ G+T + LS+TVGIHPT AEEVVK+HITKRS  DP +TGC
Sbjct:   15 LLQDRPELTPVAIMAGKLLARRLFAGSTIQMDYDNIATTVFTPLEYSTVGLSEEDAIRQYGEENLEVYHAFYKPLEFRVTEREEDVGYIKAVCLREGEQSVIGLHYLGPNAGEVMQGFAVAIRCGLTMRMLSSTVGIHPTCAEEVVKLHITKRSGEDPTVTGC 177
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Nematostella
Match: EDO49659 (Dihydrolipoyl dehydrogenase [Source:UniProtKB/TrEMBL;Acc:A7RFT6])

HSP 1 Score: 103.219 bits (256), Expect = 3.507e-23
Identity = 125/477 (26.21%), Postives = 206/477 (43.19%), Query Frame = 3 
Query:  291 LACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGR-PRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVM--VRSIPLRGFDRQMAEMVAEHMEKERKIKF-----IYGAEPVS---IIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKK--ITSGSKSNECDLEK--TTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSE--RVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAE 1670
            +A  K A L  K V+V   +S         LGGTC+NVGCIP K + + + +      A  A +    ++   + ++   M S  +N VK+L  G     ++NKV  ++ +    D   +T        + IK KN +IA G     +P I   +++ I+S     L   P   +++G   + +E        G + T +  +  I   G D ++++     ++K+  +KF     + GAE  S   ++  E  K   K ++ +         D +L  IGR P T+ L           G +K  I   S+      EK  T  PNIYAIGD +  G  L   A   G ++     N     ++YN +P  V+T  E A VG TEE     L ++  E Y     P+   S          M+  +G  E  R++G+H++   AGE++   A A++ G + + ++     HPT +E
Sbjct:   57 VAAIKAAQLGMKTVSVEKNMS---------LGGTCLNVGCIPSKALLNNSHL---YHQASGADFKNRGIEMSGVTLNLDQMMSQKENAVKALTNGIAHLFKQNKVTQVHGRGTITDTNEVTVYKDDLSTEVIKTKNILIATGSEVTPFPGIEIDEKHIISSTGALSLSTVPKNLVLIGAGVIGVELGSVWSRLGANVTAVEFLGHIGGIGIDMEISKNFQRILQKQ-GMKFKLNTKVTGAERTSDGVVVSVESAKDGSKKEELE--------ADVLLVCIGRRPYTTRL-----------GLEKVGIPLDSRGRVVVNEKFQTNVPNIYAIGDCIH-GPMLAHKAEDEG-IICVEGMNGGAVHIDYNCVPNVVYTHPEVAWVGKTEE----MLKEEGVE-YKVGKFPMSANSRARTNAEIDGMVKVLGDKETDRLLGVHMICPGAGELINEAALAMEYGASCEDIARVCHAHPTVSE 494
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Medaka
Match: txnrd2.1 (thioredoxin reductase 2 [Source:NCBI gene;Acc:101163827])

HSP 1 Score: 507.294 bits (1305), Expect = 1.441e-174
Identity = 270/494 (54.66%), Postives = 342/494 (69.23%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDLVV+GGGSGGLAC+KEAA  G++VAVLDYV PS +GT WGLGGTCVNVGCIPKKLMH  A +   ++ A   GW QI+    ++  DW  MA  VQNYVKSLNWGHRV L++ KV Y+N K    D  TI      G E  + AKN V+A GGRP+YP ++PGA ++GITSDD+FWLKKSPGKTLVVG SYVALECAGFL   G DTTVMVR+I LRGFD+QMA +V +H+E     +F + + P  + +   G  +V +   +   E SD +D++L+A+GR P T  L L  + V + + T KI  G        E ++ PNIYA GD+ +   ELTP AIKAG+LLA RL    +  MNY+ + TTVFTPLEY CVG++EEEA  R G    EVYH F+KPLE  ++      CY+K+IC+    ++++GLH LG NAGEVLQGF+ A++ G T++QL  TVGIHPTSAEE+VKI+ITKRS +DP +TGC
Sbjct:   30 YDLVVIGGGSGGLACSKEAAQLGQKVAVLDYVDPSAKGTKWGLGGTCVNVGCIPKKLMHQAALLGTAVKDAQRYGW-QIS---GTVSHDWATMAEAVQNYVKSLNWGHRVQLQDKKVTYLNLKGTLVDKHTIRGLSKAGKETILTAKNIVLATGGRPKYPSNVPGAMEHGITSDDIFWLKKSPGKTLVVGASYVALECAGFLTGIGLDTTVMVRTIALRGFDQQMAGLVTDHLE-SYGTRFEWKSVPTRVEKLSSGALKVTWTNTQTGCEHSDTFDSLLWAVGRAPETKALGLDKLGVQISKETGKIIVGPD------ESSSLPNIYAFGDIGEGRPELTPTAIKAGRLLAHRLAGRSSELMNYDNVATTVFTPLEYGCVGLSEEEAEKRHGKDGIEVYHAFYKPLEFTVAQRDSSQCYIKVICERAGHQKILGLHFLGPNAGEVLQGFSLALQCGATYRQLMQTVGIHPTSAEELVKINITKRSGLDPTVTGC 512
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Medaka
Match: txnrd3 (thioredoxin reductase 1, cytoplasmic [Source:NCBI gene;Acc:101169850])

HSP 1 Score: 447.203 bits (1149), Expect = 5.433e-150
Identity = 252/504 (50.00%), Postives = 320/504 (63.49%), Query Frame = 3 
Query:  231 NVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ---GKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            N  + +  YDL+V+GGGSGGLAC+KEAA  GK+V VLD+V P+ +GT+WGLGGTCVNVGCIPKKLMH  A +   ++ A   GW       +S+  +W  M + V NY+ SLNWG+RV+L++  V Y+NA A+F +   I AT+ +  E    A  FV+A G RPRY DIPG ++Y ITSDDLF L   PGKTLV+G SYVALEC GFL   G D TVMVRSI LRGFD+ MA    +HME E  +KFI    PV I E E    G+ +V  K  +    +   Y+T+L A+GR+ CT  + L    V V+    KI         D E+T  P+IYAIGD+L+   ELTPVAI+AGKLLARRL+ N T + +Y  +PTTVFTP+EY   G+ EE A+   G +N EVYH  F PLE  ++      CY K+I +   +ERV+G H LG NAGEV QGF AA+K GIT +QL  T+GIHPT AE    + +TK S  D    GC
Sbjct:   90 NQEDQTYDYDLIVIGGGSGGLACSKEAANLGKKVMVLDFVEPTPKGTTWGLGGTCVNVGCIPKKLMHQTALLGTALQDARKFGWEF----DESVKHNWETMKTAVNNYIGSLNWGYRVALKDKNVNYVNAYAEFVEPHKIKATNKRKKETFYTAAKFVLATGERPRYLDIPGDREYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTVMVRSILLRGFDQDMANRAGDHME-EHGVKFIRKFVPVKIEELEAGSPGRLKVTAKSTETDEIIEGEYNTVLIAVGRNACTERIGLDKAGVRVNPKNGKIPVN------DEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYGNSTLKCDYINVPTTVFTPMEYGSCGLPEERAVELYGLENIEVYHSLFWPLEFTVANRDNNKCYSKIIVNKLDNERVIGFHYLGPNAGEVTQGFGAAMKCGITKEQLDGTIGIHPTCAEIFTTLQVTKSSGGDIKQAGC 582
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Medaka
Match: txnrd3 (thioredoxin reductase 1, cytoplasmic [Source:NCBI gene;Acc:101169850])

HSP 1 Score: 446.047 bits (1146), Expect = 2.515e-149
Identity = 252/504 (50.00%), Postives = 320/504 (63.49%), Query Frame = 3 
Query:  231 NVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQ---GKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            N  + +  YDL+V+GGGSGGLAC+KEAA  GK+V VLD+V P+ +GT+WGLGGTCVNVGCIPKKLMH  A +   ++ A   GW       +S+  +W  M + V NY+ SLNWG+RV+L++  V Y+NA A+F +   I AT+ +  E    A  FV+A G RPRY DIPG ++Y ITSDDLF L   PGKTLV+G SYVALEC GFL   G D TVMVRSI LRGFD+ MA    +HME E  +KFI    PV I E E    G+ +V  K  +    +   Y+T+L A+GR+ CT  + L    V V+    KI         D E+T  P+IYAIGD+L+   ELTPVAI+AGKLLARRL+ N T + +Y  +PTTVFTP+EY   G+ EE A+   G +N EVYH  F PLE  ++      CY K+I +   +ERV+G H LG NAGEV QGF AA+K GIT +QL  T+GIHPT AE    + +TK S  D    GC
Sbjct:  114 NQEDQTYDYDLIVIGGGSGGLACSKEAANLGKKVMVLDFVEPTPKGTTWGLGGTCVNVGCIPKKLMHQTALLGTALQDARKFGWEF----DESVKHNWETMKTAVNNYIGSLNWGYRVALKDKNVNYVNAYAEFVEPHKIKATNKRKKETFYTAAKFVLATGERPRYLDIPGDREYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTVMVRSILLRGFDQDMANRAGDHME-EHGVKFIRKFVPVKIEELEAGSPGRLKVTAKSTETDEIIEGEYNTVLIAVGRNACTERIGLDKAGVRVNPKNGKIPVN------DEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYGNSTLKCDYINVPTTVFTPMEYGSCGLPEERAVELYGLENIEVYHSLFWPLEFTVANRDNNKCYSKIIVNKLDNERVIGFHYLGPNAGEVTQGFGAAMKCGITKEQLDGTIGIHPTCAEIFTTLQVTKSSGGDIKQAGC 606
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Medaka
Match: txnrd2.1 (thioredoxin reductase 2 [Source:NCBI gene;Acc:101163827])

HSP 1 Score: 419.853 bits (1078), Expect = 4.149e-141
Identity = 240/494 (48.58%), Postives = 309/494 (62.55%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYP-DIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEI-ISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDLVV+GGGSGGLAC+KE                   GT WGLGGTCVNVGCIPKKLMH  A +   ++ A   GW QI+    ++  DW  MA  VQNYVKSLNWGHRV L++ KV Y+N K    D  TI      G E  + AKN V+A GGRP+YP ++PGA ++GIT+                  S VALECAGFL   G DTTVMVR+I LRGFD+QMA +V +H+E     +F + + P  + +   G  +V +   +   E SD +D++L+A+GR P T  L L  + V + + T KI  G        E ++ PNIYA GD+ +   ELTP AIKAG+LLA RL    +  MNY+ + TTVFTPLEY CVG++EEEA  R G    EVYH F+KPLE  ++      CY+K+IC+    ++++GLH LG NAGEVLQGF+ A++ G T++QL  TVGIHPTSAEE+VKI+ITKRS +DP +TGC
Sbjct:    7 YDLVVIGGGSGGLACSKE-------------------GTKWGLGGTCVNVGCIPKKLMHQAALLGTAVKDAQRYGW-QIS---GTVSHDWATMAEAVQNYVKSLNWGHRVQLQDKKVTYLNLKGTLVDKHTIRGLSKAGKETILTAKNIVLATGGRPKYPSNVPGAMEHGITT---------------CSHSDVALECAGFLTGIGLDTTVMVRTIALRGFDQQMAGLVTDHLE-SYGTRFEWKSVPTRVEKLSSGALKVTWTNTQTGCEHSDTFDSLLWAVGRAPETKALGLDKLGVQISKETGKIIVGPD------ESSSLPNIYAFGDIGEGRPELTPTAIKAGRLLAHRLAGRSSELMNYDNVATTVFTPLEYGCVGLSEEEAEKRHGKDGIEVYHAFYKPLEFTVAQRDSSQCYIKVICERAGHQKILGLHFLGPNAGEVLQGFSLALQCGATYRQLMQTVGIHPTSAEELVKINITKRSGLDPTVTGC 455
[Close]
BLAST of Thioredoxin reductase vs. Ensembl Medaka
Match: gsr (glutathione-disulfide reductase [Source:NCBI gene;Acc:101174600])

HSP 1 Score: 226.098 bits (575), Expect = 3.249e-66
Identity = 162/472 (34.32%), Postives = 247/472 (52.33%), Query Frame = 3 
Query:  303 KEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRY---PDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIP-LRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQG---KFRVKYKKEKNPGEMSDV--YDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFN-NETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIH 1688
            + AA  G   AV++         S  LGGTCVNVGC+PKK+M + A   + +    D G+   +V+       W  + +    Y+  LN  +R +L + KV +I   A+F D    T  +  G  K+  A + +I+ GG+P      ++PGA   GI SD  F L+  P ++++VG  Y+A+E AG L   G  T++++R    LR FD  ++    + ++    I     ++  S+ + E+G       K   + N  ++S +   D +L+AIGR P T+ LN+  + V  D+    I         D + TT   IYA+GDV    + LTPVAI AG+ LA RLF   +  +++Y+ IPT VF+      VG+TEEEA+   G +N ++Y   F P+       +  C MK++C +G  E+VVGLH+ G+   E+LQGFA AIK G T +    TV IHPTS+EE V + 
Sbjct:   53 RRAAELGANAAVIE---------SHKLGGTCVNVGCVPKKVMWNAAVHAEYLHDHCDYGFETGSVR-----FSWEALKAKRDAYIAHLNRIYRNNLDKAKVTFIQGYARFTDDAEPTV-EVNG--KKYTAPHILISTGGQPSVLSDEEVPGA-SLGINSDGFFELETLPKRSVIVGAGYIAVEMAGILSTLGSKTSLIIRQTGVLRNFDALISANCTKEIQNN-GIDLWKNSQVKSVCKTEKGLEVTIVTKDPDKTNDEKISVIEEVDCLLWAIGRQPNTAGLNIGAMGVDTDDRGHIIVD-------DFQNTTRSGIYAVGDVCGKAL-LTPVAIAAGRKLAHRLFEGKKDSKLDYSCIPTVVFSHPPIGTVGLTEEEAVKTKGKENVKIYKTSFTPMYHAITRRKSQCIMKLVC-VGKEEKVVGLHMQGLGCDEMLQGFAVAIKMGATKEDFDKTVAIHPTSSEEFVTMR 496
[Close]
BLAST of Thioredoxin reductase vs. Planmine SMEST
Match: SMESG000063651.1 (SMESG000063651.1)

HSP 1 Score: 1041.57 bits (2692), Expect = 0.000e+0
Identity = 523/526 (99.43%), Postives = 524/526 (99.62%), Query Frame = 3 
Query:  153 MRFCRYAIIVTYSATRSFASGVKMNCNVNNSSKIYDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            MRFCRYAIIVTYSATRSFASGVKMNCNVNNSSKIYDLVVVGGGSGGLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQIN KPQSLIIDWPIMAS VQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVS+IEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTSDLNLSVVNVSVDEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC
Sbjct:    1 MRFCRYAIIVTYSATRSFASGVKMNCNVNNSSKIYDLVVVGGGSGGLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINAKPQSLIIDWPIMASRVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSVIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTSDLNLSVVNVSVDEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 526
[Close]
BLAST of Thioredoxin reductase vs. Planmine SMEST
Match: SMESG000020047.1 (SMESG000020047.1)

HSP 1 Score: 468.003 bits (1203), Expect = 4.251e-158
Identity = 256/498 (51.41%), Postives = 332/498 (66.67%), Query Frame = 3 
Query:  255 YDLXXXXXXXXXLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVK-----YKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 1730
            YDLVV+GGGSGGLA +KEAA FG +VAVLD+V P+ +GT+WGLGGTCVNVGCIPKKLMH  A ++   E A   GWN     P+++   W  M   +QN+++SLNWG+R SLR   V+YINA   F D  TI  TD    E+ I + NF+IA G RPRYP+IPG K+YGITSDDLF L   PGKTLV+G SYVALECAGFL + G   TVMVRSI LRGFD+QMA  + ++ME E  + FI    P  II  E+G    K     Y K+K   E  D ++T+LFAIGRDPCT  + L  V + +D+  + I +       + E++T  NIYAIGD++  G++LTPVAI+AGK L+RRLF  E    +Y  +PTTVFTPLEY  +G+TEE+AI + G ++ EV+H  FKPLE  ++      CY K+IC+   + RVVG H+L  NAGE+ QG+A A++ G T +   +T+GIHPT +E    ++ITK S  DP  +GC
Sbjct:  109 YDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNV----PETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYME-EHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKT--EYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVN-------EEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLTEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 592
[Close]
BLAST of Thioredoxin reductase vs. Planmine SMEST
Match: SMESG000069912.1 (SMESG000069912.1)

HSP 1 Score: 268.47 bits (685), Expect = 1.161e-82
Identity = 161/442 (36.43%), Postives = 253/442 (57.24%), Query Frame = 3 
Query:  381 LGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVR-SIPLRGFDRQMAEMVAEHMEKERKIKFIYGAE----PVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNET-GQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIH 1688
            +GGTCVNVGC+PKK+M++ A +R+++    + G+     K      +W I+     NY+K+LN  +  +L++N V+++  +A     +T++  +     K   A + +IA GGRP  PDIPGA + GITSD  F LK  P KT++VG  Y+ +E AG L + G +  ++ R  + LR FD+ +   V E++     +K  Y  +      SI++    +  +K    ++   +S+V D +++A+GR P T  LNL  +      G K   SG  S + D + T+ P  YA+GDV    + LTPVAI AG+ L+ RLFN++   +++Y  IPT +F+      +GMTE+EA+++ G    ++Y  FFKPL       +  C MK++C +   E+++GLH+ GM   E+LQGF+ AIK G T  Q  +TV IHPTSAEE+V + 
Sbjct:   40 MGGTCVNVGCVPKKIMYNTAMIREILRDVKNYGF-----KISYDSFNWEIIKQKRDNYIKNLNNIYESNLKQNSVKFVYGEAVTNSNKTVSVNN-----KSYTADHILIATGGRPIIPDIPGA-ELGITSDGFFELKALPKKTVIVGVGYIGIELAGILSSLGSEVILIARGDVVLRNFDKIIQTSVEENLHLS-GVKIFYKTDVEMVEYSIMDPGVLEISIKNNTNESVNTISNV-DCLIWAVGRTPNTQTLNLDKL------GIKTDKSGHISVD-DCQNTSVPGFYAVGDVCGKAL-LTPVAIAAGRRLSDRLFNDQVNSKLDYTNIPTVIFSHPPCGVIGMTEQEAVDKYGSVKVKIYRTFFKPLYFAVTERKEKCQMKLVC-LLPDEKIIGLHMCGMGCDEMLQGFSVAIKLGATKAQFDDTVAIHPTSAEELVTMR 459
[Close]
BLAST of Thioredoxin reductase vs. Planmine SMEST
Match: SMESG000047749.1 (SMESG000047749.1)

HSP 1 Score: 114.39 bits (285), Expect = 6.408e-27
Identity = 118/442 (26.70%), Postives = 207/442 (46.83%), Query Frame = 3 
Query:  381 LGGTCVNVGCIPKKLM------HHIAQMRDVIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGR-PRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVM--VRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKNPGEMSDVYDTILFAIGRDPCTXXXXXXXXXXXXXEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFK-PLEIISMGLQRPCYMKMICDIGH--SERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAE 1670
            LGGTC+NVGCIP K +      +H+A+  ++     D     +N++          M S+    V  L  G ++  + NKV ++           +T T++ G ++++  KN +IA G     +PDI   ++  ++S     LKK P K +V+G   + +E        G   T++  +  +   G D ++++ + + + K+  + F    + V+  + + GK  V     K+    +   DT+L  IGR P T +LNLS V +S D+   +I   +K       +T  PNIYAIGDV+  G  L   A   G +    +  +    ++Y  +P+ ++T  E A VG +EE+       K  ++ +   K PL   S          M+  I H  ++R++G +I+G  AGE++   A A++ G + + ++     HPT AE
Sbjct:   12 LGGTCLNVGCIPSKALLNNSHYYHMAKSNELAARGIDCSGVSLNLEK---------MMSVKNKAVSGLTGGIKMLFKSNKVTHMEGVGSITGTNEVTVTNNSGNKEKVSTKNILIATGSEVTPFPDIEIDEESIVSSTGALSLKKVPEKMIVIGAGVIGVELGSVWSRLGAQVTLVEFLGHVGGMGIDMEISKSIQKILTKQ-GLNFKLNTK-VTGAQKQGGKILVNISGTKDNKSETIDCDTLLVCIGRRPFTGNLNLSSVGLSTDD-KGRIPVNNKF------QTAVPNIYAIGDVIA-GPMLAHKAEDEGIICVEGMCGSSV-HIDYLCVPSVIYTHPEVAWVGRSEEQC------KEEKIPYKIGKFPLVANSRAKTNDDTDGMVKVIAHKDTDRLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAE 427
The following BLAST results are available for this feature:
BLAST of Thioredoxin reductase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TXNRD26.438e-17353.29thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HG... [more]
TXNRD26.810e-17154.64thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HG... [more]
TXNRD27.571e-17154.64thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HG... [more]
TXNRD29.477e-16653.05thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HG... [more]
TXNRD12.207e-15651.66thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of Thioredoxin reductase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trxr-12.200e-13548.72Thioredoxin reductase 1 [Source:UniProtKB/Swiss-P... [more]
trxr-16.953e-13548.72Thioredoxin reductase 1 [Source:UniProtKB/Swiss-P... [more]
trxr-23.744e-13446.02Probable glutathione reductase 2 [Source:UniProtK... [more]
gsr-14.456e-7136.72Glutathione reductase, mitochondrial [Source:UniP... [more]
gsr-12.533e-7037.03Glutathione reductase, mitochondrial [Source:UniP... [more]
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BLAST of Thioredoxin reductase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Trxr-15.562e-16253.40gene:FBgn0020653 transcript:FBtr0071169[more]
Trxr-13.451e-16153.54gene:FBgn0020653 transcript:FBtr0071167[more]
Trxr-18.510e-16053.54gene:FBgn0020653 transcript:FBtr0071168[more]
Trxr-22.970e-15348.90gene:FBgn0037170 transcript:FBtr0078514[more]
CG74305.958e-2326.25gene:FBgn0036762 transcript:FBtr0075140[more]
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BLAST of Thioredoxin reductase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
txnrd2.23.810e-16753.04thioredoxin reductase 2, tandem duplicate 2 [Sourc... [more]
txnrd31.850e-15050.80thioredoxin reductase 3 [Source:ZFIN;Acc:ZDB-GENE-... [more]
txnrd32.276e-15050.81thioredoxin reductase 3 [Source:ZFIN;Acc:ZDB-GENE-... [more]
txnrd2.21.443e-9653.90thioredoxin reductase 2, tandem duplicate 2 [Sourc... [more]
gsr1.116e-6634.71glutathione reductase [Source:ZFIN;Acc:ZDB-GENE-05... [more]
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BLAST of Thioredoxin reductase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpep14.231e-15851.60dipeptidase 1 [Source:Xenbase;Acc:XB-GENE-6043566][more]
nmt11.391e-15752.29N-myristoyltransferase 1 [Source:Xenbase;Acc:XB-GE... [more]
nmt12.640e-15752.29N-myristoyltransferase 1 [Source:Xenbase;Acc:XB-GE... [more]
dpep11.276e-15551.82dipeptidase 1 [Source:Xenbase;Acc:XB-GENE-6043566][more]
nmt11.363e-15452.43N-myristoyltransferase 1 [Source:Xenbase;Acc:XB-GE... [more]
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BLAST of Thioredoxin reductase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Txnrd21.926e-17453.10thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI... [more]
Txnrd21.926e-17453.10thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI... [more]
Txnrd21.926e-17453.10thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI... [more]
Txnrd21.926e-17453.10thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI... [more]
Txnrd21.452e-16952.14thioredoxin reductase 2 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of Thioredoxin reductase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9JLT4|TRXR2_MOUSE5.450e-17453.10Thioredoxin reductase 2, mitochondrial OS=Mus musc... [more]
sp|Q9NNW7|TRXR2_HUMAN3.636e-17054.64Thioredoxin reductase 2, mitochondrial OS=Homo sap... [more]
sp|Q9Z0J5|TRXR2_RAT6.754e-16954.03Thioredoxin reductase 2, mitochondrial OS=Rattus n... [more]
sp|Q9N2I8|TRXR2_BOVIN3.262e-16653.61Thioredoxin reductase 2, mitochondrial OS=Bos taur... [more]
sp|P91938|TRXR1_DROME8.530e-15953.54Thioredoxin reductase 1, mitochondrial OS=Drosophi... [more]
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BLAST of Thioredoxin reductase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A068ASV40.000e+079.70Thioredoxin reductase OS=Dugesia japonica OX=6161 ... [more]
A0A1S3JWR90.000e+054.51thioredoxin reductase 2, mitochondrial OS=Lingula ... [more]
V4AUG69.091e-17955.04Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
Q7T0L54.186e-17556.07Txnrd2 protein OS=Xenopus laevis OX=8355 GN=txnrd2... [more]
W4YIA67.597e-17553.41Uncharacterized protein OS=Strongylocentrotus purp... [more]
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BLAST of Thioredoxin reductase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
txnrd32.414e-14950.72thioredoxin reductase 1, cytoplasmic [Source:NCBI ... [more]
txnrd34.564e-14950.40thioredoxin reductase 1, cytoplasmic [Source:NCBI ... [more]
txnrd2.24.303e-13948.97thioredoxin reductase 2 [Source:NCBI gene;Acc:1030... [more]
txnrd2.24.303e-13948.97thioredoxin reductase 2 [Source:NCBI gene;Acc:1030... [more]
ENSAMXT00000055472.11.308e-13548.07pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of Thioredoxin reductase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
txnrd31.200e-15050.41thioredoxin reductase 3 [Source:ZFIN;Acc:ZDB-GENE-... [more]
dldh2.784e-2423.98dihydrolipoamide dehydrogenase [Source:ZFIN;Acc:ZD... [more]
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BLAST of Thioredoxin reductase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
GLR11.131e-7132.28Cytosolic and mitochondrial glutathione oxidoreduc... [more]
LPD11.149e-1825.83Dihydrolipoamide dehydrogenase; the lipoamide dehy... [more]
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BLAST of Thioredoxin reductase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO382287.562e-15951.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO465537.624e-13148.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO434952.968e-6735.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO465545.523e-5860.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO496593.507e-2326.21Dihydrolipoyl dehydrogenase [Source:UniProtKB/TrE... [more]
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BLAST of Thioredoxin reductase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
txnrd2.11.441e-17454.66thioredoxin reductase 2 [Source:NCBI gene;Acc:1011... [more]
txnrd35.433e-15050.00thioredoxin reductase 1, cytoplasmic [Source:NCBI ... [more]
txnrd32.515e-14950.00thioredoxin reductase 1, cytoplasmic [Source:NCBI ... [more]
txnrd2.14.149e-14148.58thioredoxin reductase 2 [Source:NCBI gene;Acc:1011... [more]
gsr3.249e-6634.32glutathione-disulfide reductase [Source:NCBI gene;... [more]
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BLAST of Thioredoxin reductase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000063651.10.000e+099.43SMESG000063651.1[more]
SMESG000020047.14.251e-15851.41SMESG000020047.1[more]
SMESG000069912.11.161e-8236.43SMESG000069912.1[more]
SMESG000047749.16.408e-2726.70SMESG000047749.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023830 ID=SMED30023830|Name=Thioredoxin reductase|organism=Schmidtea mediterranea sexual|type=transcript|length=1937bp
AATGTTTTAAAATATTGGTAATTAATAAAATTTAAAATTGGTTTTGTTAT
TGTTAAATTAAAGTTATTTCTTGATTTAAATTTTAGTTCTATTATTTTTT
GACATACTAAATTTTAAAATATAACTATTGTCTCATATTGTTGGGTTTCA
GCATGAGATTTTGTCGCTATGCTATTATTGTGACTTATAGTGCAACACGA
TCATTCGCATCAGGAGTTAAAATGAATTGTAATGTTAATAATTCTTCTAA
AATTTATGATTTAGTCGTTGTGGGAGGTGGTTCAGGAGGCTTGGCATGTG
CCAAAGAAGCTGCTTTATTTGGTAAACAAGTAGCCGTATTAGATTATGTA
TCTCCGTCAGAAAGAGGTACTTCATGGGGCTTGGGTGGCACGTGTGTAAA
TGTTGGGTGCATTCCAAAGAAATTGATGCATCACATTGCACAAATGCGAG
ACGTAATTGAGAGTGCTCATGATGCGGGATGGAATCAAATAAACGTTAAA
CCTCAATCATTAATAATAGATTGGCCTATTATGGCTTCCCTGGTGCAGAA
TTACGTCAAGAGTCTCAATTGGGGTCATAGGGTCTCACTGAGAGAAAATA
AGGTCGAGTATATCAACGCCAAGGCGAAATTCAAGGATGCACAAACGATT
ACTGCAACTGACAGCAAAGGTGTTGAGAAGGAAATCAAAGCCAAGAATTT
CGTGATAGCAGTGGGTGGCCGACCGAGATATCCCGATATTCCCGGCGCCA
AGCAATACGGCATCACGAGTGATGATTTATTCTGGTTGAAGAAATCCCCC
GGGAAAACATTGGTGGTCGGTGGTAGCTATGTAGCATTGGAGTGTGCGGG
CTTCCTTCACGCATTCGGATGTGATACGACCGTTATGGTTCGCTCGATTC
CTCTGAGGGGCTTTGATCGGCAAATGGCAGAAATGGTAGCAGAGCACATG
GAAAAAGAAAGAAAAATCAAATTCATCTATGGAGCTGAGCCTGTTTCGAT
AATCGAAGCCGAACAAGGAAAATTTCGAGTAAAGTACAAAAAAGAAAAGA
ACCCGGGAGAAATGTCGGATGTGTACGATACAATATTGTTTGCAATTGGT
AGAGATCCATGTACTTCGGATCTCAATTTATCAGTTGTCAATGTTTCGGT
TGATGAAGGCACCAAAAAAATCACTAGTGGTTCAAAATCCAACGAATGCG
ATTTGGAGAAAACGACTGCGCCAAATATTTATGCAATCGGCGATGTGCTC
AAAGACGGTGTCGAATTAACACCGGTAGCAATCAAAGCAGGGAAATTATT
GGCCAGGAGATTGTTTAACAACGAAACGGGTCAAATGAATTATAATATGA
TACCGACAACAGTGTTTACTCCTCTTGAATACGCTTGTGTCGGAATGACC
GAGGAAGAAGCAATCAACCGATTGGGAGACAAAAACACTGAGGTCTATCA
TTGCTTTTTCAAGCCACTGGAAATCATCTCGATGGGACTTCAGCGTCCAT
GCTACATGAAAATGATTTGTGATATCGGGCATTCAGAACGAGTAGTCGGG
TTGCACATTCTTGGCATGAATGCGGGAGAGGTCCTACAAGGTTTCGCTGC
AGCAATCAAGGAGGGGATTACACACAAGCAATTGAGTAACACAGTGGGCA
TTCACCCAACTTCCGCCGAGGAGGTAGTGAAAATCCATATCACAAAACGG
TCACATGTCGATCCCCACTTGACAGGATGCTGAGGTTAATTTTGGTTTCG
AGTCTTGAACAAGGGCTTGGAATCGATTTTCGAGAAACCAATGAAAATTG
ATGTTCACTTTCAATGATGGTGAATCTGGAAATGTCGAAAGCGACATCAG
ATTTCCCTGATGCGAGCATCGGTTTCATTTTATATTAGTAATGCTCATTT
ACGCGACAAATAAATTTTATTTGGCTTTTTAAAAAAA
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protein sequence of SMED30023830-orf-1

>SMED30023830-orf-1 ID=SMED30023830-orf-1|Name=SMED30023830-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=527bp
MRFCRYAIIVTYSATRSFASGVKMNCNVNNSSKIYDLVVVGGGSGGLACA
KEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRD
VIESAHDAGWNQINVKPQSLIIDWPIMASLVQNYVKSLNWGHRVSLRENK
VEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAK
QYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIP
LRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSIIEAEQGKFRVKYKKEKN
PGEMSDVYDTILFAIGRDPCTSDLNLSVVNVSVDEGTKKITSGSKSNECD
LEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMI
PTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLEIISMGLQRPC
YMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGI
HPTSAEEVVKIHITKRSHVDPHLTGC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0016491oxidoreductase activity
GO:0016668oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
GO:0050660flavin adenine dinucleotide binding
GO:0004791thioredoxin-disulfide reductase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000499cell
PLANA:0000099neuron
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR036188FAD/NAD-bd_sf
IPR006338Thioredoxin/glutathione_Rdtase
IPR001100Pyr_nuc-diS_OxRdtase
IPR004099Pyr_nucl-diS_OxRdtase_dimer
IPR023753FAD/NAD-binding_dom
IPR012999Pyr_OxRdtase_I_AS
IPR016156FAD/NAD-linked_Rdtase_dimer_sf
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
GO:0045454cell redox homeostasis
GO:0098869cellular oxidant detoxification
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00368FADPNRcoord: 218..236
score: 34.97
coord: 180..198
score: 31.92
coord: 308..324
score: 36.18
coord: 344..366
score: 30.59
coord: 37..56
score: 39.47
NoneNo IPR availablePRINTSPR00411PNDRDTASEIcoord: 486..506
score: 34.73
coord: 396..417
score: 40.24
coord: 77..92
score: 72.49
coord: 309..323
score: 42.81
coord: 464..479
score: 41.54
coord: 36..58
score: 45.61
coord: 359..366
score: 69.98
coord: 218..243
score: 34.8
coord: 183..192
score: 42.06
NoneNo IPR availablePANTHERPTHR43256FAMILY NOT NAMEDcoord: 33..518
IPR023753FAD/NAD(P)-binding domainPFAMPF07992Pyr_redox_2coord: 35..380
e-value: 3.0E-55
score: 187.5
IPR036188FAD/NAD(P)-binding domain superfamilyGENE3DG3DSA:3.50.50.60coord: 201..324
e-value: 1.5E-114
score: 384.7
IPR036188FAD/NAD(P)-binding domain superfamilyGENE3DG3DSA:3.50.50.60coord: 35..388
e-value: 1.5E-114
score: 384.7
IPR036188FAD/NAD(P)-binding domain superfamilySUPERFAMILYSSF51905FAD/NAD(P)-binding domaincoord: 32..388
IPR006338Thioredoxin/glutathione reductase selenoproteinTIGRFAMTIGR01438TIGR01438coord: 35..526
e-value: 9.6E-190
score: 629.5
IPR016156FAD/NAD-linked reductase, dimerisation domain superfamilyGENE3DG3DSA:3.30.390.30coord: 399..525
e-value: 7.8E-47
score: 160.5
IPR016156FAD/NAD-linked reductase, dimerisation domain superfamilySUPERFAMILYSSF55424FAD/NAD-linked reductases, dimerisation (C-terminal) domaincoord: 397..522
IPR004099Pyridine nucleotide-disulphide oxidoreductase, dimerisation domainPFAMPF02852Pyr_redox_dimcoord: 400..510
e-value: 1.3E-27
score: 96.3
IPR001100Pyridine nucleotide-disulphide oxidoreductase, class IPIRSFPIRSF000350Hg-II_reductase_MerAcoord: 8..518
e-value: 8.1E-63
score: 210.5
IPR012999Pyridine nucleotide-disulphide oxidoreductase, class I, active sitePROSITEPS00076PYRIDINE_REDOX_1coord: 78..88