RING-type domain-containing protein

Overview
NameRING-type domain-containing protein
Smed IDSMED30023752
Length (bp)1437
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RING-type domain-containing protein (SMED30023752) t-SNE clustered cells

Violin plots show distribution of expression levels for RING-type domain-containing protein (SMED30023752) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RING-type domain-containing protein (SMED30023752) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RING-type domain-containing protein (SMED30023752) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023752

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30023752SMESG000081443.1 Contig4776GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30023752SMESG000015149.1 PL08004A2H08ncbi_smed_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30023752SMESG000015149.1 Contig4776GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30023752SMESG000015149.1 dd_Smed_v4_9317_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF31 (ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031])

HSP 1 Score: 152.91 bits (385), Expect = 4.123e-39
Identity = 107/368 (29.08%), Postives = 166/368 (45.11%), Query Frame = 2 
Query:  356 KEISIELLNKTLSEFVVSEDIIN-------------ILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCLHRNC-TNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVKRCPT----ILTDK----NYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
             E+++ LL +T   + +  D++              +L ++C +C    P + M  +TSC C  C  C ++     +  K  TD  CP+C  R    D +   LS+ + +D       +     LFH KL +  L     F WC   +C+ GF I  +++    C  CH   C+ C  +W   HR  +CE++Q     NDP+     L   ++   I CP+C+  + L +GGCMH  C  CR +FCS C   F  + KC   NC     LH HHP +C ++ RD     L  +L+   V F+       +  P     ++  K      +D  C K       GLC+ HYKEYL  LI ++ LD +++
Sbjct:  508 AELALSLLQETPRNYELG-DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPAC-GRPDLTD-DTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATL 869
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF31 (ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031])

HSP 1 Score: 152.91 bits (385), Expect = 4.123e-39
Identity = 107/368 (29.08%), Postives = 166/368 (45.11%), Query Frame = 2 
Query:  356 KEISIELLNKTLSEFVVSEDIIN-------------ILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCLHRNC-TNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVKRCPT----ILTDK----NYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
             E+++ LL +T   + +  D++              +L ++C +C    P + M  +TSC C  C  C ++     +  K  TD  CP+C  R    D +   LS+ + +D       +     LFH KL +  L     F WC   +C+ GF I  +++    C  CH   C+ C  +W   HR  +CE++Q     NDP+     L   ++   I CP+C+  + L +GGCMH  C  CR +FCS C   F  + KC   NC     LH HHP +C ++ RD     L  +L+   V F+       +  P     ++  K      +D  C K       GLC+ HYKEYL  LI ++ LD +++
Sbjct:  508 AELALSLLQETPRNYELG-DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPAC-GRPDLTD-DTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATL 869
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF31 (ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031])

HSP 1 Score: 152.91 bits (385), Expect = 4.855e-39
Identity = 107/368 (29.08%), Postives = 166/368 (45.11%), Query Frame = 2 
Query:  356 KEISIELLNKTLSEFVVSEDIIN-------------ILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCLHRNC-TNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVKRCPT----ILTDK----NYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
             E+++ LL +T   + +  D++              +L ++C +C    P + M  +TSC C  C  C ++     +  K  TD  CP+C  R    D +   LS+ + +D       +     LFH KL +  L     F WC   +C+ GF I  +++    C  CH   C+ C  +W   HR  +CE++Q     NDP+     L   ++   I CP+C+  + L +GGCMH  C  CR +FCS C   F  + KC   NC     LH HHP +C ++ RD     L  +L+   V F+       +  P     ++  K      +D  C K       GLC+ HYKEYL  LI ++ LD +++
Sbjct:  504 AELALSLLQETPRNYELG-DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPAC-GRPDLTD-DTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATL 865
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF31 (ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031])

HSP 1 Score: 152.91 bits (385), Expect = 4.855e-39
Identity = 107/368 (29.08%), Postives = 166/368 (45.11%), Query Frame = 2 
Query:  356 KEISIELLNKTLSEFVVSEDIIN-------------ILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCLHRNC-TNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVKRCPT----ILTDK----NYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
             E+++ LL +T   + +  D++              +L ++C +C    P + M  +TSC C  C  C ++     +  K  TD  CP+C  R    D +   LS+ + +D       +     LFH KL +  L     F WC   +C+ GF I  +++    C  CH   C+ C  +W   HR  +CE++Q     NDP+     L   ++   I CP+C+  + L +GGCMH  C  CR +FCS C   F  + KC   NC     LH HHP +C ++ RD     L  +L+   V F+       +  P     ++  K      +D  C K       GLC+ HYKEYL  LI ++ LD +++
Sbjct:  504 AELALSLLQETPRNYELG-DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPAC-GRPDLTD-DTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATL 865
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: AL136295.10 (novel transcript)

HSP 1 Score: 152.525 bits (384), Expect = 6.412e-39
Identity = 107/368 (29.08%), Postives = 166/368 (45.11%), Query Frame = 2 
Query:  356 KEISIELLNKTLSEFVVSEDIIN-------------ILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCLHRNC-TNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVKRCPT----ILTDK----NYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
             E+++ LL +T   + +  D++              +L ++C +C    P + M  +TSC C  C  C ++     +  K  TD  CP+C  R    D +   LS+ + +D       +     LFH KL +  L     F WC   +C+ GF I  +++    C  CH   C+ C  +W   HR  +CE++Q     NDP+     L   ++   I CP+C+  + L +GGCMH  C  CR +FCS C   F  + KC   NC     LH HHP +C ++ RD     L  +L+   V F+       +  P     ++  K      +D  C K       GLC+ HYKEYL  LI ++ LD +++
Sbjct:  659 AELALSLLQETPRNYELG-DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPAC-GRPDLTD-DTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATL 1020
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 68.5514 bits (166), Expect = 5.415e-12
Identity = 64/249 (25.70%), Postives = 100/249 (40.16%), Query Frame = 2 
Query:  437 QCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKE--PMIECEY--CHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLM--------------KVMKTIEIK-CPRCQ---VQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTR 1117
            +CP+C    P S    +  C    C  CL++++  +I T+   +  CP C S +   D  +       LI+  +         LR   L +  + RWCP   C   F I  K    P ++C+   C +  C HC  +WH N+TC+E +    +    L                 +K  ++K CPRC+   V+ D   G C H+ C  C  EFC  C K              + LH   P+ C ++ +
Sbjct:   54 ECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYVELSI-TENRVEVPCPECSSYLHPNDIKMLIGDIPTLIEKYEAFS------LR-RYLMTEADARWCPAPDCGFVF-IATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMD--DGSCNHMVCTMCNAEFCWLCLKEI------------SDLHYLSPTGCTFWGK 279
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 68.5514 bits (166), Expect = 5.415e-12
Identity = 64/249 (25.70%), Postives = 100/249 (40.16%), Query Frame = 2 
Query:  437 QCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKE--PMIECEY--CHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLM--------------KVMKTIEIK-CPRCQ---VQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTR 1117
            +CP+C    P S    +  C    C  CL++++  +I T+   +  CP C S +   D  +       LI+  +         LR   L +  + RWCP   C   F I  K    P ++C+   C +  C HC  +WH N+TC+E +    +    L                 +K  ++K CPRC+   V+ D   G C H+ C  C  EFC  C K              + LH   P+ C ++ +
Sbjct:   54 ECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYVELSI-TENRVEVPCPECSSYLHPNDIKMLIGDIPTLIEKYEAFS------LR-RYLMTEADARWCPAPDCGFVF-IATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMD--DGSCNHMVCTMCNAEFCWLCLKEI------------SDLHYLSPTGCTFWGK 279
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 68.5514 bits (166), Expect = 5.832e-12
Identity = 64/249 (25.70%), Postives = 100/249 (40.16%), Query Frame = 2 
Query:  437 QCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKE--PMIECEY--CHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLM--------------KVMKTIEIK-CPRCQ---VQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTR 1117
            +CP+C    P S    +  C    C  CL++++  +I T+   +  CP C S +   D  +       LI+  +         LR   L +  + RWCP   C   F I  K    P ++C+   C +  C HC  +WH N+TC+E +    +    L                 +K  ++K CPRC+   V+ D   G C H+ C  C  EFC  C K              + LH   P+ C ++ +
Sbjct:   84 ECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYVELSI-TENRVEVPCPECSSYLHPNDIKMLIGDIPTLIEKYEAFS------LR-RYLMTEADARWCPAPDCGFVF-IATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMD--DGSCNHMVCTMCNAEFCWLCLKEI------------SDLHYLSPTGCTFWGK 309
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 68.5514 bits (166), Expect = 5.832e-12
Identity = 64/249 (25.70%), Postives = 100/249 (40.16%), Query Frame = 2 
Query:  437 QCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKE--PMIECEY--CHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLM--------------KVMKTIEIK-CPRCQ---VQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTR 1117
            +CP+C    P S    +  C    C  CL++++  +I T+   +  CP C S +   D  +       LI+  +         LR   L +  + RWCP   C   F I  K    P ++C+   C +  C HC  +WH N+TC+E +    +    L                 +K  ++K CPRC+   V+ D   G C H+ C  C  EFC  C K              + LH   P+ C ++ +
Sbjct:   84 ECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYVELSI-TENRVEVPCPECSSYLHPNDIKMLIGDIPTLIEKYEAFS------LR-RYLMTEADARWCPAPDCGFVF-IATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMD--DGSCNHMVCTMCNAEFCWLCLKEI------------SDLHYLSPTGCTFWGK 309
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 68.5514 bits (166), Expect = 5.975e-12
Identity = 64/249 (25.70%), Postives = 100/249 (40.16%), Query Frame = 2 
Query:  437 QCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKE--PMIECEY--CHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLM--------------KVMKTIEIK-CPRCQ---VQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTR 1117
            +CP+C    P S    +  C    C  CL++++  +I T+   +  CP C S +   D  +       LI+  +         LR   L +  + RWCP   C   F I  K    P ++C+   C +  C HC  +WH N+TC+E +    +    L                 +K  ++K CPRC+   V+ D   G C H+ C  C  EFC  C K              + LH   P+ C ++ +
Sbjct:   84 ECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYVELSI-TENRVEVPCPECSSYLHPNDIKMLIGDIPTLIEKYEAFS------LR-RYLMTEADARWCPAPDCGFVF-IATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMD--DGSCNHMVCTMCNAEFCWLCLKEI------------SDLHYLSPTGCTFWGK 309
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: LUBEL (gene:FBgn0031857 transcript:FBtr0331220)

HSP 1 Score: 175.637 bits (444), Expect = 7.500e-47
Identity = 114/377 (30.24%), Postives = 178/377 (47.21%), Query Frame = 2 
Query:  326 KSYLKQKLISKEISIELLNKTLSEFVVSEDI--------------INILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSC-----PSRMTKIDRNIHFLS-----FRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLM-----KVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQG-KC-LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVK-------------RCPTIL---TDKNYKDFKCNKNCY-KNVGLCEDHYKEYL 1297
            + Y+ Q+L++  I+   +  TL     SED+              I +L ++C +C++ +P++ M++M  C  + C  C K +    I  +   D  CP C      +     D ++ + S      ++++D+D  +  LF  KLRD  L    NF+WC   +C++GF  R K++ +I C  C S  C  C   W   H   +CE Y     +NDP+L      + +    I CP+C+ ++ L +GGCMH  C  C+ EFC  C + F  G KC +   C   GLHAHHP NC ++ RD    +L  +LK+  V+F   + + +K             RCP  L   T +   D  CN     K+ G+C  HY EYL
Sbjct: 2410 RKYVDQELVTN-IAEAQIAATLVSMKFSEDVALWAARECSDLDQAIAMLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDND--VHELFQRKLRDRSLLQDPNFKWCI--QCSSGFFARPKQKRLI-CPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRDKIPLQLQFLLKEQNVKFDT-EPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYL 2779
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: LUBEL (gene:FBgn0031857 transcript:FBtr0331216)

HSP 1 Score: 175.637 bits (444), Expect = 7.522e-47
Identity = 114/377 (30.24%), Postives = 178/377 (47.21%), Query Frame = 2 
Query:  326 KSYLKQKLISKEISIELLNKTLSEFVVSEDI--------------INILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSC-----PSRMTKIDRNIHFLS-----FRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLM-----KVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQG-KC-LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVK-------------RCPTIL---TDKNYKDFKCNKNCY-KNVGLCEDHYKEYL 1297
            + Y+ Q+L++  I+   +  TL     SED+              I +L ++C +C++ +P++ M++M  C  + C  C K +    I  +   D  CP C      +     D ++ + S      ++++D+D  +  LF  KLRD  L    NF+WC   +C++GF  R K++ +I C  C S  C  C   W   H   +CE Y     +NDP+L      + +    I CP+C+ ++ L +GGCMH  C  C+ EFC  C + F  G KC +   C   GLHAHHP NC ++ RD    +L  +LK+  V+F   + + +K             RCP  L   T +   D  CN     K+ G+C  HY EYL
Sbjct: 2463 RKYVDQELVTN-IAEAQIAATLVSMKFSEDVALWAARECSDLDQAIAMLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDND--VHELFQRKLRDRSLLQDPNFKWCI--QCSSGFFARPKQKRLI-CPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRDKIPLQLQFLLKEQNVKFDT-EPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYL 2832
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: LUBEL (gene:FBgn0031857 transcript:FBtr0331221)

HSP 1 Score: 175.252 bits (443), Expect = 9.201e-47
Identity = 114/377 (30.24%), Postives = 178/377 (47.21%), Query Frame = 2 
Query:  326 KSYLKQKLISKEISIELLNKTLSEFVVSEDI--------------INILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSC-----PSRMTKIDRNIHFLS-----FRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLM-----KVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQG-KC-LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVK-------------RCPTIL---TDKNYKDFKCNKNCY-KNVGLCEDHYKEYL 1297
            + Y+ Q+L++  I+   +  TL     SED+              I +L ++C +C++ +P++ M++M  C  + C  C K +    I  +   D  CP C      +     D ++ + S      ++++D+D  +  LF  KLRD  L    NF+WC   +C++GF  R K++ +I C  C S  C  C   W   H   +CE Y     +NDP+L      + +    I CP+C+ ++ L +GGCMH  C  C+ EFC  C + F  G KC +   C   GLHAHHP NC ++ RD    +L  +LK+  V+F   + + +K             RCP  L   T +   D  CN     K+ G+C  HY EYL
Sbjct: 2369 RKYVDQELVTN-IAEAQIAATLVSMKFSEDVALWAARECSDLDQAIAMLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDND--VHELFQRKLRDRSLLQDPNFKWCI--QCSSGFFARPKQKRLI-CPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRDKIPLQLQFLLKEQNVKFDT-EPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYL 2738
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: LUBEL (gene:FBgn0031857 transcript:FBtr0331218)

HSP 1 Score: 175.252 bits (443), Expect = 9.229e-47
Identity = 114/377 (30.24%), Postives = 178/377 (47.21%), Query Frame = 2 
Query:  326 KSYLKQKLISKEISIELLNKTLSEFVVSEDI--------------INILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSC-----PSRMTKIDRNIHFLS-----FRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLM-----KVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQG-KC-LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVK-------------RCPTIL---TDKNYKDFKCNKNCY-KNVGLCEDHYKEYL 1297
            + Y+ Q+L++  I+   +  TL     SED+              I +L ++C +C++ +P++ M++M  C  + C  C K +    I  +   D  CP C      +     D ++ + S      ++++D+D  +  LF  KLRD  L    NF+WC   +C++GF  R K++ +I C  C S  C  C   W   H   +CE Y     +NDP+L      + +    I CP+C+ ++ L +GGCMH  C  C+ EFC  C + F  G KC +   C   GLHAHHP NC ++ RD    +L  +LK+  V+F   + + +K             RCP  L   T +   D  CN     K+ G+C  HY EYL
Sbjct: 2422 RKYVDQELVTN-IAEAQIAATLVSMKFSEDVALWAARECSDLDQAIAMLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDND--VHELFQRKLRDRSLLQDPNFKWCI--QCSSGFFARPKQKRLI-CPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRDKIPLQLQFLLKEQNVKFDT-EPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYL 2791
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: ari-1 (gene:FBgn0017418 transcript:FBtr0089508)

HSP 1 Score: 62.7734 bits (151), Expect = 2.952e-10
Identity = 52/214 (24.30%), Postives = 90/214 (42.06%), Query Frame = 2 
Query:  434 RQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKWHRNETCEEYQ--FRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCK--NCRIEFCSCCKKTFRQGKCLHRNC 1063
             +C IC    P  +M  +  C   FC  C  E+L+  I  +        SC +    I   +  ++  NL+ +D +++  +   + +  ++ ++  RWCP+  CT    +   +   + C+  H F C  C   WH    C   +   +   +D +    +     +CPRC V  +   GGC H+ CK  NC+ EFC  C  ++        NC
Sbjct:  131 EECEICFSQLPPDSMAGL-ECGHRFCMPCWHEYLSTKIVAEGLGQ--TISCAAHGCDI--LVDDVTVANLV-TDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVKVPYAEPRRVHCKCGHVF-CFACGENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIE-KDGGCNHMVCKNQNCKNEFCWVCLGSWEPHGSSWYNC 336
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-181m9.8 (si:dkey-181m9.8 [Source:ZFIN;Acc:ZDB-GENE-070912-399])

HSP 1 Score: 153.68 bits (387), Expect = 4.199e-40
Identity = 101/332 (30.42%), Postives = 148/332 (44.58%), Query Frame = 2 
Query:  419 INILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKC--LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKN------------YKDFKCNKNCYKNV-GLCEDHYKEYLCLLIFSYDLD 1327
            +  L   CPIC +    + M+ MT CSC FC  C K++ +  I  K      CP C     +  R    + + +L+D+      D ++  LF  KLRD  L+   NFRWC +  C  G  +       ++C  C    C  C   W   H   +CE+++     N P+     L +++   +I CP+C+ +F L +GGC+H +C  C+ EFC  C + F+QG        C   GLHAHHP NC Y  RD  +  L ++L++     P   + K  P     K              K+  C +  +    G C  HYKE L  LI S  LD
Sbjct:  211 LKYLCHDCPICQEQVSFNRMVTMTHCSCTFCESCFKKYFSSVIKEKNIVHAVCPLCNLPDVRGGRREDTMEYFSLLDTQIRYYLDSQIHELFQRKLRDRALQEMPNFRWCAH--CCFGL-LHEADRLRMDCPSCGKSTCFKCKRPWAPQHEGISCEKFKEWEQLNSPEYQNSRLEQLLSRNKIDCPKCKFRFFLARGGCLHFRCTQCQHEFCGGCSQPFKQGSTCNFSIECAAKGLHAHHPRNCLYHLRDWSVPRLRTLLQRYGVSHPLMFSPKH-PMGRHSKGICGVMEFQETGAVKEEACGRQAFPEYSGYCTLHYKEVLVELINSNGLD 538
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: FO834800.1 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:100334178])

HSP 1 Score: 149.443 bits (376), Expect = 4.634e-38
Identity = 90/278 (32.37%), Postives = 136/278 (48.92%), Query Frame = 2 
Query:  365 SIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKK 1156
            ++E + + + E    + I  +L ++CPICL  FP S M ++TSC C  C  C ++     +  K   D  CP C      I+   H  S+ + +D       ++++  LFH KL ++ L     F WC    C+ GF I +  +  + C  C    C  C   W   H   +CE++Q    +NDP+     L   ++   I CP C+ Q+ L +GGCMH  C  CR +FCS C   F    C    CT TGLHAHHP +C ++ RD +   L ++L+K
Sbjct:  662 TLEDVVQAVRESPDRDFIRRVLNKECPICLSVFPHSKMRSLTSCQCSVCCGCFQQHFTIAVRDKHIRDMVCPVC--TEPDINDPEHLNSYFSTLDIQLRDCLEQEVYELFHKKLTEQALIKDPKFLWC--SHCSYGF-IYDDDQLKVTCSQCRKSFCAQCKKTWEPQHMGLSCEQFQLWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALARGGCMHFSCSQCRYQFCSGCNNPFHT-TCAVNQCTVTGLHAHHPRDCLFYLRDWEPARLQALLQK 933
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: FO834800.2 (E3 ubiquitin-protein ligase RNF31-like [Source:NCBI gene;Acc:108179742])

HSP 1 Score: 129.028 bits (323), Expect = 7.862e-34
Identity = 78/241 (32.37%), Postives = 116/241 (48.13%), Query Frame = 2 
Query:  476 MINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKK 1156
            M ++TSC C  C  C ++     +  K   D  CP C      I+   H  S+ + +D       ++++  LFH KL ++ L     F WC +  C+ GF I +  +  + C  C    C  C   W   H   +CE++Q    +NDP+     L   ++   I CP C+ Q+ L +GGCMH  C  CR +FCS C   F    C    CT TGLHAHHP +C ++ RD +   L ++L+K
Sbjct:    1 MRSLTSCQCSVCCGCFQQHFTIAVRDKHIRDMVCPVCTE--PDINDPEHLNSYFSTLDIQLRDCLEQEVYELFHKKLTEQALIKDPKFLWCSH--CSYGF-IYDDDQLKVTCSQCRKSFCAQCKKTWEPQHMGLSCEQFQLWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALARGGCMHFSCSQCRYQFCSGCNNPFHT-TCAVNQCTVTGLHAHHPRDCLFYLRDWEPARLQALLQK 235
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: rnf144aa (ring finger protein 144aa [Source:NCBI gene;Acc:570968])

HSP 1 Score: 71.2478 bits (173), Expect = 3.040e-13
Identity = 56/231 (24.24%), Postives = 97/231 (41.99%), Query Frame = 2 
Query:  386 TLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKK---EPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRT----------LKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF 1033
            T + +  + D+    +  C +CL  FPL  M  +T C C FC +CLK+++   I     T   CP  +CP R    +  I  +    ++   +KL+        ++++    +  WCP+  C     ++        ++ C  C    C  C   WH ++ C+E    T           K D D   +      +CP+C+V  +  + GC  + CKNC+  FC  C ++ 
Sbjct:    2 TTARYRPTWDLALDPLVSCKLCLGEFPLEQMTTITQCQCVFCTMCLKQYVELLIKEGFETAISCPDSACPKRGHLQENEIECMVATEIMQRYRKLQF-------EKEVLLDPSRTWCPSSTCQAVCQLKESDTVLPQLVRCSVCTLEFCSACKASWHPDQDCQENVPITSFLPGESSSFFKADDDDAPIK-----RCPKCKVYIERDE-GCAQMMCKNCKHAFCWYCLESL 219
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: rnf144ab (ring finger protein 144ab [Source:NCBI gene;Acc:437000])

HSP 1 Score: 70.8626 bits (172), Expect = 4.282e-13
Identity = 56/224 (25.00%), Postives = 98/224 (43.75%), Query Frame = 2 
Query:  392 SEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPM---IECEYCHSFVCLHCNVKWHRNETCEEY----QFRTLKNDPDLMKVMKTIEIK-CPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF 1033
            S +  S D+    +  C +CL  FPL  M  ++ C C FC +CLK+++   I     T   CP  +CP +   ++  I  +    ++   K+L+  F  ++  +  ++     WCP+  C     +   +  +   ++C  C    C  C    H  + C+E      F   +N  +L        IK CP+C+V  +  + GC  + CKNC+  FC  C ++ 
Sbjct:    4 SRYEPSWDVDLAPLLSCKLCLGEFPLEQMTTISQCQCIFCSLCLKQYVELLIKEGLETAISCPDSTCPKQGHLLENEIECMVAGEVMQHYKRLQ--FEREVLLDPCRT-----WCPSSSCQAVCQLNEAEVQLPQPVQCPECSLRFCSACRADCHTGQACQEMLPITTFLPGENGSNLKSQEDEAPIKRCPKCKVYIERDE-GCAQMMCKNCKHAFCWYCLESL 219
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf31 (ring finger protein 31 [Source:NCBI gene;Acc:100036616])

HSP 1 Score: 142.51 bits (358), Expect = 1.052e-35
Identity = 107/361 (29.64%), Postives = 162/361 (44.88%), Query Frame = 2 
Query:  308 LHNENFKSYLKQKLISKEISIELLN--KTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS-RMTKIDRNIHFLSFRNLIDSDK---KLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLMKVMKTI-----EIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQ-GKCLHRNCT-NTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKNYKDFKCNKNCYK-----NVGLCEDHYKEYLCLLIFSYDLD 1327
            LH+          LI  E   EL +  + + E    + I  +L ++C +C    P + M ++TSC C  C  C +      +  K   D  CP+C    ++     +H+ S  +++  D       +LFH KL +  L     F WC +  C+ GF I  + +  ++C  C    C  C   W   HR+  C+++Q    +ND +       +      I CP C+  + L +GGCMH  C  CR +FCS C  TF Q  KC   +CT    LHAHHP +C ++ RD D+  L  +L+  +        VK    ++  K   D   ++ C K       GLCE HYKEYL   I ++ LD
Sbjct:  518 LHSWGRAELALSLLIEGEGRYELQDVVEAVRESQDRDFIKRMLTQECAVCGWELPRNKMRSLTSCECCICPDCFRMHFTVAVKEKHIRDMICPACEEPEISDEGELLHYFSTLDILLRDTLEVDAYDLFHKKLTERTLMKDPKFLWCTH--CSFGF-IYERDQLDVKCPQCQCSFCRKCKRPWEEQHRSLNCDDFQNWKRENDAEYQAQGLAVYLLENGITCPHCKFSYALARGGCMHFICSQCRHQFCSGCYNTFHQRNKCTVPSCTVRMSLHAHHPRDCLFYLRDWDVTRLQRLLQVSKLS-----EVKGGCRVMEQKEIPDGLRDEACGKITPPGYAGLCESHYKEYLVSRINAHSLD 870
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf31 (ring finger protein 31 [Source:NCBI gene;Acc:100036616])

HSP 1 Score: 142.51 bits (358), Expect = 1.150e-35
Identity = 107/361 (29.64%), Postives = 162/361 (44.88%), Query Frame = 2 
Query:  308 LHNENFKSYLKQKLISKEISIELLN--KTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS-RMTKIDRNIHFLSFRNLIDSDK---KLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLMKVMKTI-----EIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQ-GKCLHRNCT-NTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKNYKDFKCNKNCYK-----NVGLCEDHYKEYLCLLIFSYDLD 1327
            LH+          LI  E   EL +  + + E    + I  +L ++C +C    P + M ++TSC C  C  C +      +  K   D  CP+C    ++     +H+ S  +++  D       +LFH KL +  L     F WC +  C+ GF I  + +  ++C  C    C  C   W   HR+  C+++Q    +ND +       +      I CP C+  + L +GGCMH  C  CR +FCS C  TF Q  KC   +CT    LHAHHP +C ++ RD D+  L  +L+  +        VK    ++  K   D   ++ C K       GLCE HYKEYL   I ++ LD
Sbjct:  514 LHSWGRAELALSLLIEGEGRYELQDVVEAVRESQDRDFIKRMLTQECAVCGWELPRNKMRSLTSCECCICPDCFRMHFTVAVKEKHIRDMICPACEEPEISDEGELLHYFSTLDILLRDTLEVDAYDLFHKKLTERTLMKDPKFLWCTH--CSFGF-IYERDQLDVKCPQCQCSFCRKCKRPWEEQHRSLNCDDFQNWKRENDAEYQAQGLAVYLLENGITCPHCKFSYALARGGCMHFICSQCRHQFCSGCYNTFHQRNKCTVPSCTVRMSLHAHHPRDCLFYLRDWDVTRLQRLLQVSKLS-----EVKGGCRVMEQKEIPDGLRDEACGKITPPGYAGLCESHYKEYLVSRINAHSLD 866
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf31 (ring finger protein 31 [Source:NCBI gene;Acc:100036616])

HSP 1 Score: 141.739 bits (356), Expect = 2.029e-35
Identity = 107/361 (29.64%), Postives = 162/361 (44.88%), Query Frame = 2 
Query:  308 LHNENFKSYLKQKLISKEISIELLN--KTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS-RMTKIDRNIHFLSFRNLIDSDK---KLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLMKVMKTI-----EIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQ-GKCLHRNCT-NTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKNYKDFKCNKNCYK-----NVGLCEDHYKEYLCLLIFSYDLD 1327
            LH+          LI  E   EL +  + + E    + I  +L ++C +C    P + M ++TSC C  C  C +      +  K   D  CP+C    ++     +H+ S  +++  D       +LFH KL +  L     F WC +  C+ GF I  + +  ++C  C    C  C   W   HR+  C+++Q    +ND +       +      I CP C+  + L +GGCMH  C  CR +FCS C  TF Q  KC   +CT    LHAHHP +C ++ RD D+  L  +L+  +        VK    ++  K   D   ++ C K       GLCE HYKEYL   I ++ LD
Sbjct:  568 LHSWGRAELALSLLIEGEGRYELQDVVEAVRESQDRDFIKRMLTQECAVCGWELPRNKMRSLTSCECCICPDCFRMHFTVAVKEKHIRDMICPACEEPEISDEGELLHYFSTLDILLRDTLEVDAYDLFHKKLTERTLMKDPKFLWCTH--CSFGF-IYERDQLDVKCPQCQCSFCRKCKRPWEEQHRSLNCDDFQNWKRENDAEYQAQGLAVYLLENGITCPHCKFSYALARGGCMHFICSQCRHQFCSGCYNTFHQRNKCTVPSCTVRMSLHAHHPRDCLFYLRDWDVTRLQRLLQVSKLS-----EVKGGCRVMEQKEIPDGLRDEACGKITPPGYAGLCESHYKEYLVSRINAHSLD 920
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf31 (ring finger protein 31 [Source:NCBI gene;Acc:100036616])

HSP 1 Score: 141.739 bits (356), Expect = 2.256e-35
Identity = 106/361 (29.36%), Postives = 163/361 (45.15%), Query Frame = 2 
Query:  308 LHNENFKSYLKQKLISKEISIELLN--KTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS-RMTKIDRNIHFLSFRNLIDSDK---KLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLMKVMKTI-----EIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQ-GKCLHRNCT-NTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKNYKDFKCNKNCYK-----NVGLCEDHYKEYLCLLIFSYDLD 1327
            LH+          LI  E   EL +  + + E    + I  +L ++C +C    P + M ++TSC C  C  C +      +  K   D  CP+C    ++     +H+ S  +++  D       +LFH KL +  L     F WC +  C+ GF I  + +  ++C  C    C  C   W   HR+  C+++Q    +ND +       +      I CP C+  + L +GGCMH  C  CR +FCS C  TF Q  KC   +CT    LHAHHP +C ++ RD D+  L  +L+  +    +   +  C  ++  K   D   ++ C K       GLCE HYKEYL   I ++ LD
Sbjct:  567 LHSWGRAELALSLLIEGEGRYELQDVVEAVRESQDRDFIKRMLTQECAVCGWELPRNKMRSLTSCECCICPDCFRMHFTVAVKEKHIRDMICPACEEPEISDEGELLHYFSTLDILLRDTLEVDAYDLFHKKLTERTLMKDPKFLWCTH--CSFGF-IYERDQLDVKCPQCQCSFCRKCKRPWEEQHRSLNCDDFQNWKRENDAEYQAQGLAVYLLENGITCPHCKFSYALARGGCMHFICSQCRHQFCSGCYNTFHQRNKCTVPSCTVRMSLHAHHPRDCLFYLRDWDVTRLQRLLQVSKLSEVKGTLLCGC-RVMEQKEIPDGLRDEACGKITPPGYAGLCESHYKEYLVSRINAHSLD 923
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf31 (ring finger protein 31 [Source:NCBI gene;Acc:100036616])

HSP 1 Score: 139.043 bits (349), Expect = 1.908e-34
Identity = 106/367 (28.88%), Postives = 163/367 (44.41%), Query Frame = 2 
Query:  308 LHNENFKSYLKQKLISKEISIELLN--KTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS-RMTKIDRNIHFLSFRNLIDSDK---KLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLMKVMKTI-----EIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQ-GKCLHRNCT-NTGLHAHHPSNCQYFTRDNDIN--ELNSILKKVEFHAPQKLNVKRCPT----ILTDKNYKDFKCNKNCYK-----NVGLCEDHYKEYLCLLIFSYDLD 1327
            LH+          LI  E   EL +  + + E    + I  +L ++C +C    P + M ++TSC C  C  C +      +  K   D  CP+C    ++     +H+ S  +++  D       +LFH KL +  L     F WC +  C+ GF I  + +  ++C  C    C  C   W   HR+  C+++Q    +ND +       +      I CP C+  + L +GGCMH  C  CR +FCS C  TF Q  KC   +CT    LHAHHP +C ++ RD D+   +    +  V+F+       +  P     ++  K   D   ++ C K       GLCE HYKEYL   I ++ LD
Sbjct:  529 LHSWGRAELALSLLIEGEGRYELQDVVEAVRESQDRDFIKRMLTQECAVCGWELPRNKMRSLTSCECCICPDCFRMHFTVAVKEKHIRDMICPACEEPEISDEGELLHYFSTLDILLRDTLEVDAYDLFHKKLTERTLMKDPKFLWCTH--CSFGF-IYERDQLDVKCPQCQCSFCRKCKRPWEEQHRSLNCDDFQNWKRENDAEYQAQGLAVYLLENGITCPHCKFSYALARGGCMHFICSQCRHQFCSGCYNTFHQRNKCTVPSCTVRMSLHAHHPRDCLFYLRDWDVTRLQRLLQMLLVQFNTDPPAGTQTAPGGGCRVMEQKEIPDGLRDEACGKITPPGYAGLCESHYKEYLVSRINAHSLD 892
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf31 (ring finger protein 31 [Source:MGI Symbol;Acc:MGI:1934704])

HSP 1 Score: 154.836 bits (390), Expect = 6.686e-40
Identity = 108/366 (29.51%), Postives = 167/366 (45.63%), Query Frame = 2 
Query:  359 EISIELLNKTLSEFVV---------SED---IINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCLHRNC-TNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVKRCPT----ILTDK----NYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
            E+++ LL +T   + +         S+D   +  +L ++C +C    P + M  + SC C  C  C ++     +  K  TD  CP+C  R    D +   LS+ + +D       D     LFH KL +  L     F WC   +C+ GF I  +++    C  CH   C+ C  +W   HR  +CE++Q     NDP+     L   ++   I CP+C+  + L +GGCMH  C  CR +FCS C   F  + KC   NC     LH HHP +C ++ RD     L  +L+   V F+       +  P     ++  K     ++D  C K       GLC+ HYKEYL  LI ++ LD +++
Sbjct:  500 ELALALLQETPRNYELLDVVEAVRHSQDRAFLRRLLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPAC-GRPDLTD-DAQLLSYFSTLDIQLRESLDPDAYALFHKKLTEAVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQDNNVMFNTEPPAGTRAVPGGGCRVMEQKEVHSGFRDEACGKETPPGYAGLCQAHYKEYLVSLINAHSLDPATL 860
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf31 (ring finger protein 31 [Source:MGI Symbol;Acc:MGI:1934704])

HSP 1 Score: 154.836 bits (390), Expect = 6.799e-40
Identity = 108/366 (29.51%), Postives = 167/366 (45.63%), Query Frame = 2 
Query:  359 EISIELLNKTLSEFVV---------SED---IINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCLHRNC-TNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVKRCPT----ILTDK----NYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
            E+++ LL +T   + +         S+D   +  +L ++C +C    P + M  + SC C  C  C ++     +  K  TD  CP+C  R    D +   LS+ + +D       D     LFH KL +  L     F WC   +C+ GF I  +++    C  CH   C+ C  +W   HR  +CE++Q     NDP+     L   ++   I CP+C+  + L +GGCMH  C  CR +FCS C   F  + KC   NC     LH HHP +C ++ RD     L  +L+   V F+       +  P     ++  K     ++D  C K       GLC+ HYKEYL  LI ++ LD +++
Sbjct:  654 ELALALLQETPRNYELLDVVEAVRHSQDRAFLRRLLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPAC-GRPDLTD-DAQLLSYFSTLDIQLRESLDPDAYALFHKKLTEAVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQDNNVMFNTEPPAGTRAVPGGGCRVMEQKEVHSGFRDEACGKETPPGYAGLCQAHYKEYLVSLINAHSLDPATL 1014
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf144a (ring finger protein 144A [Source:MGI Symbol;Acc:MGI:1344401])

HSP 1 Score: 70.4774 bits (171), Expect = 5.868e-13
Identity = 56/228 (24.56%), Postives = 95/228 (41.67%), Query Frame = 2 
Query:  386 TLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKIDRNIHFLSFRNLIDSDKKL---KNLFHDKLRDEKLKSSKNFRWCPNEKCT---NGFDIRNKKEPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRT-LKNDPDLMKVMKTIEI---KCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF 1033
            T + +  + D+    +  C +CL  +P   M  +  C C FC +CLK+++   I     T   CP  +CP +    +  I  +    ++   KKL   + +  D  R           WCP   C       DI  +   +++C+ C    C  C  +WH  + C E    T L  +      M+  +    +CP+C+V  +  + GC  + CKNC+  FC  C ++ 
Sbjct:    2 TTARYRPTWDLALDPLVSCKLCLGEYPAEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRT----------WCPASTCQAVCQLQDIGLQTPQLVQCKACDMEFCSACKARWHPGQGCPETMPITFLPGETSSAFKMEEGDAPIKRCPKCRVYIERDE-GCAQMMCKNCKHAFCWYCLESL 218
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf144a (ring finger protein 144A [Source:MGI Symbol;Acc:MGI:1344401])

HSP 1 Score: 70.4774 bits (171), Expect = 5.868e-13
Identity = 56/228 (24.56%), Postives = 95/228 (41.67%), Query Frame = 2 
Query:  386 TLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKIDRNIHFLSFRNLIDSDKKL---KNLFHDKLRDEKLKSSKNFRWCPNEKCT---NGFDIRNKKEPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRT-LKNDPDLMKVMKTIEI---KCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF 1033
            T + +  + D+    +  C +CL  +P   M  +  C C FC +CLK+++   I     T   CP  +CP +    +  I  +    ++   KKL   + +  D  R           WCP   C       DI  +   +++C+ C    C  C  +WH  + C E    T L  +      M+  +    +CP+C+V  +  + GC  + CKNC+  FC  C ++ 
Sbjct:    2 TTARYRPTWDLALDPLVSCKLCLGEYPAEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRT----------WCPASTCQAVCQLQDIGLQTPQLVQCKACDMEFCSACKARWHPGQGCPETMPITFLPGETSSAFKMEEGDAPIKRCPKCRVYIERDE-GCAQMMCKNCKHAFCWYCLESL 218
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf31 (ring finger protein 31 [Source:MGI Symbol;Acc:MGI:1934704])

HSP 1 Score: 65.855 bits (159), Expect = 6.861e-13
Identity = 32/81 (39.51%), Postives = 43/81 (53.09%), Query Frame = 2 
Query:  923 IKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCLHRNC-TNTGLHAHHPSNCQYFTRDNDINELNSILKKV 1159
            I CP+C+  + L +GGCMH  C  CR +FCS C   F  + KC   NC     LH HHP +C ++ RD     L  +L+  
Sbjct:    3 IDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQGT 83
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8IPJ3|LUBEL_DROME (E3 ubiquitin-protein ligase lubel OS=Drosophila melanogaster OX=7227 GN=LUBEL PE=1 SV=2)

HSP 1 Score: 175.637 bits (444), Expect = 7.540e-46
Identity = 114/377 (30.24%), Postives = 178/377 (47.21%), Query Frame = 2 
Query:  326 KSYLKQKLISKEISIELLNKTLSEFVVSEDI--------------INILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSC-----PSRMTKIDRNIHFLS-----FRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLM-----KVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQG-KC-LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVK-------------RCPTIL---TDKNYKDFKCNKNCY-KNVGLCEDHYKEYL 1297
            + Y+ Q+L++  I+   +  TL     SED+              I +L ++C +C++ +P++ M++M  C  + C  C K +    I  +   D  CP C      +     D ++ + S      ++++D+D  +  LF  KLRD  L    NF+WC   +C++GF  R K++ +I C  C S  C  C   W   H   +CE Y     +NDP+L      + +    I CP+C+ ++ L +GGCMH  C  C+ EFC  C + F  G KC +   C   GLHAHHP NC ++ RD    +L  +LK+  V+F   + + +K             RCP  L   T +   D  CN     K+ G+C  HY EYL
Sbjct: 2463 RKYVDQELVTN-IAEAQIAATLVSMKFSEDVALWAARECSDLDQAIAMLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDND--VHELFQRKLRDRSLLQDPNFKWCI--QCSSGFFARPKQKRLI-CPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRDKIPLQLQFLLKEQNVKFDT-EPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYL 2832
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q924T7|RNF31_MOUSE (E3 ubiquitin-protein ligase RNF31 OS=Mus musculus OX=10090 GN=Rnf31 PE=1 SV=2)

HSP 1 Score: 154.836 bits (390), Expect = 4.756e-39
Identity = 108/366 (29.51%), Postives = 167/366 (45.63%), Query Frame = 2 
Query:  359 EISIELLNKTLSEFVV---------SED---IINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCLHRNC-TNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVKRCPT----ILTDK----NYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
            E+++ LL +T   + +         S+D   +  +L ++C +C    P + M  + SC C  C  C ++     +  K  TD  CP+C  R    D +   LS+ + +D       D     LFH KL +  L     F WC   +C+ GF I  +++    C  CH   C+ C  +W   HR  +CE++Q     NDP+     L   ++   I CP+C+  + L +GGCMH  C  CR +FCS C   F  + KC   NC     LH HHP +C ++ RD     L  +L+   V F+       +  P     ++  K     ++D  C K       GLC+ HYKEYL  LI ++ LD +++
Sbjct:  654 ELALALLQETPRNYELLDVVEAVRHSQDRAFLRRLLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPAC-GRPDLTD-DAQLLSYFSTLDIQLRESLDPDAYALFHKKLTEAVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQDNNVMFNTEPPAGTRAVPGGGCRVMEQKEVHSGFRDEACGKETPPGYAGLCQAHYKEYLVSLINAHSLDPATL 1014
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q96EP0|RNF31_HUMAN (E3 ubiquitin-protein ligase RNF31 OS=Homo sapiens OX=9606 GN=RNF31 PE=1 SV=1)

HSP 1 Score: 152.525 bits (384), Expect = 3.079e-38
Identity = 107/368 (29.08%), Postives = 166/368 (45.11%), Query Frame = 2 
Query:  356 KEISIELLNKTLSEFVVSEDIIN-------------ILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCLHRNC-TNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVKRCPT----ILTDK----NYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
             E+++ LL +T   + +  D++              +L ++C +C    P + M  +TSC C  C  C ++     +  K  TD  CP+C  R    D +   LS+ + +D       +     LFH KL +  L     F WC   +C+ GF I  +++    C  CH   C+ C  +W   HR  +CE++Q     NDP+     L   ++   I CP+C+  + L +GGCMH  C  CR +FCS C   F  + KC   NC     LH HHP +C ++ RD     L  +L+   V F+       +  P     ++  K      +D  C K       GLC+ HYKEYL  LI ++ LD +++
Sbjct:  659 AELALSLLQETPRNYELG-DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPAC-GRPDLTD-DTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATL 1020
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|A4IIY1|R144A_XENTR (Probable E3 ubiquitin-protein ligase RNF144A OS=Xenopus tropicalis OX=8364 GN=rnf144a PE=2 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 1.510e-12
Identity = 58/229 (25.33%), Postives = 94/229 (41.05%), Query Frame = 2 
Query:  386 TLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKIDRNIHFLSFRNLIDSDKKL---KNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKK---EPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLMKVMKTIE-----IKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF 1033
            T + +  + D+    +  C +CL  + +  M  +  C C FC +CLK+++   I     T   CP  SCP R    +  I  +    ++   KKL   K +  D  R           WCP+  C     ++ K      +++C  C    C  C   WH  + C E    T     D     K++E      +CP+C+V  +  + GC  + CKNC+  FC  C ++ 
Sbjct:    2 TTARYRPTWDLALEPLVSCKLCLGEYTVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDASCPKRGHLQENEIECMVAAEIMQKYKKLQFEKEILLDPCR----------TWCPSSSCQAVCKLQEKGIQNPQLVQCSACDIEFCSACKANWHPGQGCPENMAITFLPG-DSSSFFKSLEDDVPIKRCPKCKVYIERDE-GCAQMMCKNCKHAFCWYCLESL 218
[Close]
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5RFV4|R1441_DANRE (Probable E3 ubiquitin-protein ligase RNF144A-A OS=Danio rerio OX=7955 GN=rnf144aa PE=3 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 2.295e-12
Identity = 56/231 (24.24%), Postives = 97/231 (41.99%), Query Frame = 2 
Query:  386 TLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKK---EPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRT----------LKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF 1033
            T + +  + D+    +  C +CL  FPL  M  +T C C FC +CLK+++   I     T   CP  +CP R    +  I  +    ++   +KL+        ++++    +  WCP+  C     ++        ++ C  C    C  C   WH ++ C+E    T           K D D   +      +CP+C+V  +  + GC  + CKNC+  FC  C ++ 
Sbjct:    2 TTARYRPTWDLALDPLVSCKLCLGEFPLEQMTTITQCQCVFCTMCLKQYVELLIKEGFETAISCPDSACPKRGHLQENEIECMVATEIMQRYRKLQF-------EKEVLLDPSRTWCPSSTCQAVCQLKESDTVLPQLVRCSVCTLEFCSACKASWHPDQDCQENVPITSFLPGESSSFFKADDDDAPIK-----RCPKCKVYIERDE-GCAQMMCKNCKHAFCWYCLESL 219
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A2T7NIC0 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_19059 PE=4 SV=1)

HSP 1 Score: 199.904 bits (507), Expect = 1.089e-51
Identity = 126/382 (32.98%), Postives = 194/382 (50.79%), Query Frame = 2 
Query:  281 AKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVSED---IINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRN--------IHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGF--DIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCS-CCKKTFRQGKCLH-RNCTNTGLHAHHPSNCQYFTRDNDINELNSILK--KVEFHAPQKLN---VKRCPTILTDKNYKDFKCNKNCYKN-----VGLCEDHYKEYLCLLIFSYDLD 1327
             + +L+I +L ++   +Y  Q + + E     L   +      ED    +  LM++C IC  ++P+S + N+  C C+ C  CLK+     I  K    W CP C    +K D N        I+FL     +  DK++ +LF  K+RD  L+   +FRWC +  C NGF  D  +++  M+ C +C    C  C  +W   H   TCE++    + NDP+     L + ++   I CP C++++ L KGGCMH KC  C  EFCS CC+  +++G C   +NC   GLHAHHP +C ++ RD D+  L  +L+   VEF+     N     RCP ++  K +   K +++C K+      GLC  HYKEYL  LI   ++D
Sbjct: 1414 GRAELVIKLLDHDLPAAYSSQGITNGEDYYCTLEDVVEAVRNCEDKRSALVYLMQECQICFSHYPMSKIRNLNFCQCKICSDCLKQNFEVVIREKHVRHWTCPLC----SKPDLNDEELGSEYINFLGMLLQMQVDKEVYDLFETKVRDWHLQKDPHFRWCAH--CGNGFIADGGDRQLKMV-CPHCSQKTCYQCKKQWEEQHEGVTCEQFAQWKIDNDPNNQAVGLARHLEENGIDCPSCKMRYALAKGGCMHFKCPQCGHEFCSGCCQPFYQRGMCNRLKNCKMNGLHAHHPRDCFFYLRDCDVQHLQVLLQNANVEFNTVPPANQEETSRCP-VIEQKEFDSGKRDESCGKDSGDGLAGLCLLHYKEYLVGLINKNNID 1787
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A084VI46 (AGAP007788-PA-like protein OS=Anopheles sinensis OX=74873 GN=ZHAS_00004878 PE=4 SV=1)

HSP 1 Score: 190.66 bits (483), Expect = 1.359e-48
Identity = 113/347 (32.56%), Postives = 169/347 (48.70%), Query Frame = 2 
Query:  422 NILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCP------SRMTKIDRNIHFLSFRNLIDS--DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLM-----KVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQG-KC-LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSIL--KKVEF-----------HAPQKLNVKRCPTIL---TDKNYKDFKCNKNC-YKNVGLCEDHYKEYLCLLIFSYDLDVSSISKRFIN 1357
            ++L ++C +CL  FP++ +++M  C+   C  C KE+  + I  +  T+  CP C       S +T+ D   +F +   L+ S  D+++ +LF  K+RD  L    NF+WC +  C++GF  R K+   + C  C S  C  C   W   H   TCE+Y      NDP+L      + ++T  I CP C+ ++ L +GGCMH  C  C+ EFC  C K F  G KC +   C   GLHAHHP NC ++ RD +  +L ++L    V F           H   +  + +CP  L   T     D  C+     K+ GLC  HY EYL          VS++SK  I+
Sbjct: 3387 DLLQKECELCLGVFPMNEIVSMLKCTHTCCLECAKEYFTQEITNRSITNCNCPYCKEPNLNGSDVTEDDVLEYFSNLDILLKSIVDEEVHDLFQRKIRDRTLTQDPNFKWCVH--CSSGFFARPKQR-RLTCPDCGSITCASCRKPWESQHEGLTCEKYAEWKEANDPELQAEGVQRHLQTHGISCPNCKFRYSLARGGCMHFTCTQCKFEFCYGCNKPFMMGAKCSVSPYCAKLGLHAHHPRNCLFYLRDKEPRDLQNLLLMNNVPFDTEPSEMMKQEHMNGQSTIPKCPIPLQKETPAGLMDMICSAEVPEKHAGLCRTHYVEYL----------VSTVSKAQID 3720
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A182X1H8 (RING-type domain-containing protein OS=Anopheles quadriannulatus OX=34691 PE=4 SV=1)

HSP 1 Score: 189.504 bits (480), Expect = 4.489e-48
Identity = 109/341 (31.96%), Postives = 167/341 (48.97%), Query Frame = 2 
Query:  410 EDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS------RMTKIDRNIHFLSFRNLIDS--DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLM-----KVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQG-KC-LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSIL--KKVEFHAPQKLNVK-----------RCPTIL---TDKNYKDFKCNKNC-YKNVGLCEDHYKEYLCLLIFSYDLD 1327
            +D  ++L ++C +CL  FP++ +I+M  C+   C  C KE+  + I  +  T+  CP C         +T+ D   +F +   L+ +  D+++ +LF  K+RD  L    NF+WC +  C++GF  R K+  ++ C  C S  C  C   W   H   TCE++      NDP+L      + ++T  I CP C+ ++ L +GGCMH  C  C+ EFC  C K F  G KC +   C   GLHAHHP NC ++ RD +  +L ++L    V F       +K           +CP  L   T     D  C+ +   K+ GLC  HY EYL  L+    +D
Sbjct: 3231 DDAKDLLQKECELCLGVFPMNEIISMLKCTHTCCFECAKEYFTQEITNRSITNCNCPYCKEPDLNGPEVTEDDVLEYFSNLDILLKNIVDEEVHDLFQRKIRDRTLTKDPNFKWCVH--CSSGFFARPKQRRLV-CPDCGSITCASCRKAWEAQHEGLTCEKFAEWKEANDPELQAEGVQRHLQTHGISCPNCKFRYSLARGGCMHFTCTQCKFEFCYGCNKPFMMGAKCSVSPYCAKLGLHAHHPRNCLFYLRDKEPRDLQNLLLMNNVSFDTEPSEQMKQELANGESTTMKCPIPLQKETPAGLMDMICSADVPEKHAGLCRPHYVEYLSFLVTHNSID 3568
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A182IEF9 (RING-type domain-containing protein OS=Anopheles arabiensis OX=7173 PE=4 SV=1)

HSP 1 Score: 189.504 bits (480), Expect = 4.491e-48
Identity = 109/341 (31.96%), Postives = 167/341 (48.97%), Query Frame = 2 
Query:  410 EDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS------RMTKIDRNIHFLSFRNLIDS--DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLM-----KVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQG-KC-LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSIL--KKVEFHAPQKLNVK-----------RCPTIL---TDKNYKDFKCNKNC-YKNVGLCEDHYKEYLCLLIFSYDLD 1327
            +D  ++L ++C +CL  FP++ +I+M  C+   C  C KE+  + I  +  T+  CP C         +T+ D   +F +   L+ +  D+++ +LF  K+RD  L    NF+WC +  C++GF  R K+  ++ C  C S  C  C   W   H   TCE++      NDP+L      + ++T  I CP C+ ++ L +GGCMH  C  C+ EFC  C K F  G KC +   C   GLHAHHP NC ++ RD +  +L ++L    V F       +K           +CP  L   T     D  C+ +   K+ GLC  HY EYL  L+    +D
Sbjct: 3247 DDAKDLLQKECELCLGVFPMNEIISMLKCTHTCCFECAKEYFTQEITNRSITNCNCPYCKEPDLNGPEVTEDDVLEYFSNLDILLKNIVDEEVHDLFQRKIRDRTLTKDPNFKWCVH--CSSGFFARPKQRRLV-CPDCGSITCASCRKAWETQHEGLTCEKFAEWKEANDPELQAEGVQRHLQTHGISCPNCKFRYSLARGGCMHFTCTQCKFEFCYGCNKPFMMGAKCSVSPYCAKLGLHAHHPRNCLFYLRDKEPRDLQNLLLMNNVSFDTEPSEQMKQELANGESTTMKCPIPLQKETPAGLMDMICSADVPEKHAGLCRPHYVEYLSFLVTHNSID 3584
[Close]
BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A433U6J9 (RanBP2-type domain-containing protein (Fragment) OS=Elysia chlorotica OX=188477 GN=EGW08_002851 PE=4 SV=1)

HSP 1 Score: 189.119 bits (479), Expect = 4.974e-48
Identity = 121/383 (31.59%), Postives = 190/383 (49.61%), Query Frame = 2 
Query:  281 AKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCP-SRMTKIDRNIHFLSF-----RNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPM-IECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF-RQGKCL-HRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFH--AP-QKLNVKRCPTI----LTDKNYKDFKCNKNCYK-NVGLCEDHYKEYLCLLIFSYDLD-VSSISK 1345
             + D++I +L  +   + +++ L    +++E + + + +       +  L ++C IC   FP++ + N+ +C C  C  C        I  K    W CP C    ++ +D   ++L F     + +I  D  L++LF  K RD  L+    FRWC +  C  GF   N    + + C  C    C +C  +W   H   TCEE+    + NDP      L K +    I CP C+++F L KGGCMH KC  C  EFCS C + +  +  C+ ++ C N GLH H P +C  F RD  + +L ++L+K  V F+  AP  +L+   CP +       +  +D KC ++  +   GLCE+HYKEYL +LI S  LD VS +SK
Sbjct: 1586 GRADMVIKILDQD---AEIQEDLDEGRVTLEDIVEAVRDCQDRASALAYLRQECQICFGRFPMNKIYNLNTCQCRLCQECFVSHFEVAIREKHVRHWVCPQCSLPDLSDLDEASNYLQFLGMQLKPMIGQD--LRDLFETKFRDWHLQKMDLFRWCAH--CAEGFLAENLGGQLRMTCPRCGERTCFNCKKQWEDQHEGLTCEEFSQWKVDNDPTNQSVGLAKHLDENGIDCPACKMRFALAKGGCMHFKCPQCGHEFCSGCNEPYHHKNMCVRYKLCKNLGLHCHCPRDCFSFLRDYTVKQLQTLLEKHTVTFNVAAPADQLDRAHCPVVEQKEFDGEGNRDEKCGRDALQGGAGLCENHYKEYLVVLINSQSLDPVSLMSK 1961
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000014446.2 (ring finger protein 31 [Source:NCBI gene;Acc:103030581])

HSP 1 Score: 166.007 bits (419), Expect = 8.979e-44
Identity = 103/330 (31.21%), Postives = 156/330 (47.27%), Query Frame = 2 
Query:  416 IINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLID------SDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKLNVKRCP-TILTDKNYKDFKCNKNCYK-----NVGLCEDHYKEYLCLLIFSYDLDVSSI 1339
            I  +L ++CPICL  FP S M ++TSC C  C  C K+     +  K   D  CP C      I+   H  S+ + +D       + ++  LFH KL ++ L     F WC    C+ GF I +  +  + C  C +  C  C   W   H   +CE++Q    +NDP+     L   ++   I CP C+ Q+ L +GGCMH  C  CR +FCS C   F    C    C+ TGLHAHHP +C ++ RD +   L ++L+K  V ++       +     ++  K+    + +  C         GLCE HY+EYL  LI  + +D + +
Sbjct:  691 IRRVLAKECPICLSVFPHSKMQSLTSCQCSVCSGCFKQHFTIAVRDKHIRDMVCPVC--WEPDINNPEHLNSYFSTLDIQLRECVEPEVYELFHKKLTEQALIKDPKFLWC--SHCSYGF-IYDGDQLKVTCLQCRNSFCAQCKKPWEAQHNGLSCEQFQLWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALARGGCMHFSCSQCRYQFCSGCNNPFHT-TCAVAQCSVTGLHAHHPRDCLFYLRDWEPARLQALLQKNGVAYNTDTAPGTQTGVCGVIEQKDEGPRQTDSACGAQTQPGQAGLCEKHYREYLVSLINGHSIDPAPL 1014
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000018785.2 (E3 ubiquitin-protein ligase RNF31-like [Source:NCBI gene;Acc:103042649])

HSP 1 Score: 160.999 bits (406), Expect = 4.369e-42
Identity = 109/346 (31.50%), Postives = 160/346 (46.24%), Query Frame = 2 
Query:  359 EISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMT----KIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILK--KVEFHA--PQKLNVKRCPTILTDKNYK--DFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
            E S+E + + + E    + I  IL ++C IC   FP   M  +T C C  C  C  +     +  K   D  CP C          ++     L  +  ++ + ++ +LF  KL +  LK    F WC +  CTNGF I  K E  + C+ C    C  C   W   H   TC ++Q    +NDP+     L+  ++   IKCP C+ Q+ L KGGCMH  C  CR EFC  C   F +  C    C + G HAHHP +C Y+ RD +   L ++L+  KVEF+   P       C  +   +  +  D  C     +   GLC+ HY+EYL  LI ++ LD + +
Sbjct:  654 EYSVEDVIQAVREHHDKDFINRILKKECQICYASFPQRKMQALTFCQCSMCSECFIQHFTVALRDKHIRDMVCPVCEEPEINDPEALETYFFTLDVQLRLNLEPEVYDLFGKKLMEHTLKKDPKFLWCCH--CTNGF-IYEKDELKVTCQNCRKSFCSKCKKAWEDQHEGLTCNDFQKWKRENDPEYQKQGLVGFLRENGIKCPSCKFQYALAKGGCMHFTCSQCRYEFCCGCNNPFHKKPCPGNQCISKGFHAHHPRDCLYYLRDWEPVRLQALLQKHKVEFNTDHPDGTGNGLCGVMEQKEGGQALDDACGIQVEEGHAGLCDKHYREYLVSLINAHSLDPADL 996
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: si:dkey-181m9.8 (E3 ubiquitin-protein ligase RNF31-like [Source:NCBI gene;Acc:103040600])

HSP 1 Score: 148.288 bits (373), Expect = 8.545e-38
Identity = 102/334 (30.54%), Postives = 147/334 (44.01%), Query Frame = 2 
Query:  419 INILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSC-PSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKC--LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKNY-------------KDFKCNKNCYKNV-GLCEDHYKEYLCLLIFSYDLD 1327
            +  L   CPIC +      MI MT CSC FC  C K + +  I  K      CP C    +    R    + + +L+D+      D +   LF  KLRD+ L+   NFRWC +  C+ G  +       ++C  C    C +C   W   H   +CE+++     N P+     L  ++   +I CP+C+ +F L KGGC+H KC  C+ EFC  C + FR G        C   GLHAHHP +C Y  RD D+  L S+L+      P  +  +R  ++L  +               ++  C +       G C  HYKE L  LI    LD
Sbjct:  450 LKYLSHDCPICQEQMSFGKMITMTHCSCTFCESCFKAYFSSVIKEKSIVHAVCPMCNQPDVRGAGRREESMEYFSLLDTQIRHYLDPQTHELFQRKLRDQALQEMPNFRWCAH--CSFGL-LHEADRLRMDCPNCGKSTCFNCKSPWASQHEGLSCEKFKEWQQLNSPEYQNSRLELLLSRNKIDCPKCRFRFFLSKGGCLHFKCTQCQHEFCGGCSRPFRNGSACNFSAECGTKGLHAHHPRDCLYHLRDWDVARLCSLLQHHGVAHP-LIYSQRDGSVLGSQRVVCAVFEHKELGSPREEPCGRVALPEYNGYCTLHYKECLVELIKQNGLD 779
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf144aa (probable E3 ubiquitin-protein ligase RNF144A-A [Source:NCBI gene;Acc:103040762])

HSP 1 Score: 74.7146 bits (182), Expect = 1.513e-14
Identity = 58/229 (25.33%), Postives = 96/229 (41.92%), Query Frame = 2 
Query:  386 TLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKIDRNIHFLSFRNLIDSDKKL---KNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNK---KEPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLMKVMKTIE-----IKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF 1033
            T + +  + D+    +  C +CL  FPL  M  +T C C FC +CLK+++   I     T   CP  +CP R    +  I  +    ++   +KL   K +  D  R           WCP+  C     ++     +  ++ C  C    C  C   WH ++ C+E    T     +     K+ E      +CP+C+V  +  + GC  + CKNC+  FC  C ++ 
Sbjct:    2 TTARYRPTWDLALDPLVSCKLCLGEFPLEKMTTITQCQCVFCTLCLKQYVELLIKEGLETAISCPDSACPKRGHLQENEIECMVATEIMQRYRKLQFEKEVLLDPCR----------TWCPSSSCQAVCQLKEADATRPQLVRCSNCTLEFCSACKASWHPDQDCQENPPITAFLPGETSSFFKSDEDDAPIKRCPKCKVYIERDE-GCAQMMCKNCKHAFCWYCLESL 219
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf144aa (probable E3 ubiquitin-protein ligase RNF144A-A [Source:NCBI gene;Acc:103040762])

HSP 1 Score: 73.9442 bits (180), Expect = 3.229e-14
Identity = 58/229 (25.33%), Postives = 96/229 (41.92%), Query Frame = 2 
Query:  386 TLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKIDRNIHFLSFRNLIDSDKKL---KNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNK---KEPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLMKVMKTIE-----IKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF 1033
            T + +  + D+    +  C +CL  FPL  M  +T C C FC +CLK+++   I     T   CP  +CP R    +  I  +    ++   +KL   K +  D  R           WCP+  C     ++     +  ++ C  C    C  C   WH ++ C+E    T     +     K+ E      +CP+C+V  +  + GC  + CKNC+  FC  C ++ 
Sbjct:    2 TTARYRPTWDLALDPLVSCKLCLGEFPLEKMTTITQCQCVFCTLCLKQYVELLIKEGLETAISCPDSACPKRGHLQENEIECMVATEIMQRYRKLQFEKEVLLDPCR----------TWCPSSSCQAVCQLKEADATRPQLVRCSNCTLEFCSACKASWHPDQDCQENPPITAFLPGETSSFFKSDEDDAPIKRCPKCKVYIERDE-GCAQMMCKNCKHAFCWYCLESL 219
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006434.1 (pep scaffold:Pmarinus_7.0:GL492086:439:5313:1 gene:ENSPMAG00000005812.1 transcript:ENSPMAT00000006434.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 119.783 bits (299), Expect = 1.839e-31
Identity = 83/245 (33.88%), Postives = 119/245 (48.57%), Query Frame = 2 
Query:  629 SFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRN----------CTNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHAPQKL----NVKRCPTILTDKNYKDFKCNKNCYKNV-----GLCE 1276
             FRN +D +  +  LF +K+RD  L    NFRWC +  C NG  I +     ++C YC+   C  C   W   H   TCE +    L NDP+     L   +K   I CP+C+ ++ L KGGCMH  C  C+ EFCS C     + + +HR+          CT+ GLHAHHP +C ++ RD DI  L ++L    + F+   +L    N      +L  K+  +   ++ C K V     GLCE
Sbjct:    1 QFRNYLDPE--VFRLFENKMRDRALYMMPNFRWCAH--CPNG-SIHDALRLRMDCTYCNKSTCSKCKKPWEVQHEGLTCEAFHTWKLDNDPEMQAAGLAAFLKENGIACPKCKFRYALAKGGCMHFTCGQCKHEFCSGCYNPAAE-RSVHRDVNPESECGMGCTHMGLHAHHPRDCLHYLRDWDIARLQALLTDHNLAFNVQPRLGTVANTAGYCEVLEQKDMANGLRDEPCGKAVADQQAGLCE 239
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007741.1 (pep scaffold:Pmarinus_7.0:GL477427:676:25209:1 gene:ENSPMAG00000006996.1 transcript:ENSPMAT00000007741.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.9366 bits (167), Expect = 1.453e-12
Identity = 51/223 (22.87%), Postives = 82/223 (36.77%), Query Frame = 2 
Query:  440 CPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPN-EKCTNGFDIRNKKEPMIECEYCHSFVCLHCN-VKWHRNETCEEYQ--------FRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNT 1072
            CPICL       ++    C+   C  C + +L  +I         CP   CP++ T           R +++ D     L+   L    ++S  N  WC N + C               C  CH   C  C+ ++ H   +C +          +  + +D     + K I   CP C  Q +  +G C+H+ C  C   FC  C K +      + NC+ T
Sbjct: 1393 CPICLGVTGEVELLAPLYCTHRCCKSCWRAYLKTSIDQNMLAKCTCPIMDCPAQPTGA-------FIRTMMEDDSDRLELYKRALLRGYVESCSNLAWCANPQGCDRVLCKDGTGGHAATCAKCHWSTCFSCSFLEAHCPASCNQIAWWVDEGGYYEGMSSDALSKHLAKLISKPCPSCHAQIEKNEG-CLHMTCAKCNHSFCWRCLKAWAPTHTEYYNCSTT 1607
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: rnf19a (ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-030131-9414])

HSP 1 Score: 61.6178 bits (148), Expect = 2.012e-10
Identity = 62/244 (25.41%), Postives = 96/244 (39.34%), Query Frame = 2 
Query:  437 QCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRN---KKEPMIECE--YCHSFVCLHCNVKWHRNETCEEY--------QFRTLKNDPD--LMKVMKTIEIK-CPRCQVQ-FDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTR 1117
            +CP+CL      +   + SC    C  CL+++L   I ++   +  CP C  R+     N H +     I +D  L   + + +    L +  + RWCP   C  GF +        P + CE   C +  C HC   WH N+TC+          + R++++             +IK CPRC      +  G C H+ C  C  EFC  C K                LH   PS C ++ +
Sbjct:  109 ECPLCLVRRSAEHFPELLSCPHRSCLDCLRQYLRIEI-SESRVNICCPECAERL-----NPHDI---QRILADATLMGKYEEFMLRRFLVADPDCRWCPAPDC--GFAVIATGCASCPKLTCEREGCGTEFCYHCKAMWHPNQTCDAARQQRSATLRLRSIQSASASYSQDGAHADDIKPCPRCAAYIMKMNDGSCNHMTCAVCGCEFCWLCMKEISD------------LHYLSPSGCTFWGK 329
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006333.1 (pep scaffold:Pmarinus_7.0:GL479789:448:31336:-1 gene:ENSPMAG00000005679.1 transcript:ENSPMAT00000006333.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 1.019e-9
Identity = 48/220 (21.82%), Postives = 87/220 (39.55%), Query Frame = 2 
Query:  440 CPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCN-VKWHRNETCEEYQ--------FRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCT 1066
            CP+CL      + I    C    C  C +E+L+  +     T+  CP   C ++         F+  R++++  +     ++  L    ++S  N  WC N +  +     +       C  CH   C  CN ++ H   +C            +  + ++     + K I  +CP CQ Q +  +G C+H+ C  C   FC  C K ++     + NC+
Sbjct: 1992 CPVCL--LTTVDHIAPLCCRHSCCKSCWREYLSMRVEQNMVTNCKCPISECLAQPPP-----DFI--RSILECMRFAPPQYNRGLVRCYVESCTNLTWCTNPQGCDRILCTDSIGHAGTCAKCHWSSCFSCNFLEAHYPASCGHMSQWMDDGGYYEGMNSEALSKHLAKLISKRCPSCQAQIEKNEG-CLHMTCAKCNHGFCWRCLKPWKPTHKDYYNCS 2201
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Yeast
Match: HEL1 (RING finger ubiquitin ligase (E3); involved in ubiquitination and degradation of excess histones; interacts with Ubc4p and Rad53p; null mutant sensitive to hydroxyurea (HU) [Source:SGD;Acc:S000001725])

HSP 1 Score: 53.9138 bits (128), Expect = 2.872e-8
Identity = 36/143 (25.17%), Postives = 66/143 (46.15%), Query Frame = 2 
Query:  647 DSDKKLKNLFHDKLRDEKLKS-----SKNFRWCPNEKCTNGFDIRNKKE----------PMIECEYCHSFVCLHCNVKWHRNETCE--EYQFRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCK 1024
            D DK + +    KL D  +KS     ++N++WCP   C +   +R+             P ++C   H F C +C  + H    C+      +  + + +++  + +   +CP+C V  +   GGC H+ C +C+ EFC  C+
Sbjct:  231 DIDKVMGHPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRDTSSLPEYTRLHYSPFVKCNSFHRF-CFNCGFEVHSPADCKITTAWVKKARKESEILNWVLSHTKECPKCSVNIE-KNGGCNHMVCSSCKYEFCWICE 371
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO46475 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ03])

HSP 1 Score: 169.859 bits (429), Expect = 1.461e-45
Identity = 112/380 (29.47%), Postives = 175/380 (46.05%), Query Frame = 2 
Query:  269 PSLRAKVDLLISVLHNENFKSYLKQ-KLISKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLID------SDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGK--CLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPT-----ILTDKNYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
            PS + +V ++++     ++   L   KLI +  ++E       +    E     L R+C +C+D  P + MI M +C C FC  C+ +++ + I  +      CP+C S    ++ +    ++ NL+D       D    +LF  KLRD  L    NFRWC +  C++GF         + C +CH + C  C  +W   H   +CE++      NDP+     L   +K   I+CP C+ ++DL KGGCMH KC  C  E+CS C   FR G    +  +C   GLHAHHP +C ++ RD D  EL  +L +       +      P         +   +D +C +       GLC  HY EYL   + +  +D  SI
Sbjct:  588 PSRQRRVRVMLAQKSMLSWGRALTAIKLIDENFAVEDSIIAAQDNGDLERSKKFLQRECIVCMDLKPENRMITMLNCQCRFCSDCVSQYVKQIIQEQNIMHLVCPAC-SEPKNLEDDTVATNYFNLLDILIRPLVDNPTHDLFQRKLRDRTLMKEPNFRWCSH--CSSGFINERPGILKMPCPHCHKYTCFQCKKQWEDQHEGISCEQFAAWKEANDPEAQATGLAAHLKQNGIECPNCKFRYDLAKGGCMHFKCGQCSHEYCSGCYGPFRHGAHCPVSPHCAMRGLHAHHPRDCLFYLRDRDPEELQQLLAENNVAFDTEEGAAAAPGHCRVMEQAEAGTEDKECGRPTPDGYAGLCRMHYIEYLVERVNANLIDPVSI 964
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO37437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFQ2])

HSP 1 Score: 64.3142 bits (155), Expect = 1.764e-11
Identity = 54/208 (25.96%), Postives = 85/208 (40.87%), Query Frame = 2 
Query:  440 CPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPS--CPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKWHRNETCE-------EYQFRTLKNDPDLMKVMKTIEIK-CPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTF 1033
            C ICL   P      + SC C FC  CLK+++   I         CP   CP +   ++  I  L   +L  + +K++ +       ++++ SK+  +CP   C    +        + C  C    C  C   WH  + C+         +F  L N  +++     +EIK CP CQV     + GC  + C NC+  FC  C K  
Sbjct:   24 CKICLADCPTKKGAILKSCGCFFCKECLKQYVAHAIADGSVLQIPCPDGVCPDKGDLMESEIADLIAEDLFQNFQKMRAI-------KEIQISKSKAFCPKPDCKGVVESIPGAAKEVCCSECGYSFCFACKGPWHPEKHCQNKGEKANGIKFFELVNGEEVL-----VEIKACPTCQVLIQRDE-GCAQMMCGNCKHIFCWHCLKGL 218
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO36616 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI45])

HSP 1 Score: 59.3066 bits (142), Expect = 1.538e-9
Identity = 52/198 (26.26%), Postives = 85/198 (42.93%), Query Frame = 2 
Query:  440 CPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKWHRNETCEEYQ--FRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKN--CRIEFCSCC 1021
            C IC    P++N   +  C   FC  C KE+L   I  +   +    SCP+  TK D  +   +F   I +D K+K+ +H  + +  + S++  +WCP   C N           + C  C    C  C+   H    C   +   +   +D +    +     +CP+C V  +   GGC H+ C+N  C+ +FC  C
Sbjct:  139 CNICFCPIPVANFTGL-ECGDRFCQRCWKEYLTTKIIDEHVGE--NISCPA--TKCDILVD-EAFVGQIIADPKVKSQYHHLIANSFVVSNRLMKWCPGPDCDNAIKANYHDALPVTC-LCGFTFCFGCSEPVHEPVKCVWLKKWIKKTNDDSETSNWISANTKECPKCHVTIE-KNGGCNHMVCRNTACKADFCWVC 328
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO48096 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK36])

HSP 1 Score: 57.7658 bits (138), Expect = 4.834e-9
Identity = 60/267 (22.47%), Postives = 106/267 (39.70%), Query Frame = 2 
Query:  440 CPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPM---IECEYCHSFVCLHCNVKWHRNETCEEYQFRTLK--NDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCT-----------NTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVK 1192
            CP+C    P +  I++  C   FC  C        +    ++   C +C       +  +      N++   K L+  F + L ++++K+    RWCP   C  GF +R  +EP    + C  C++  C  C  K+H    C   +    K  +D +    +      CP C    +   GGC H++C  C+ +FC  C  T++     +  C+           + G+ A        F  +   N  +S+ K+ E    +K+N K
Sbjct:  120 CPVCFQRMPRTVTISL-PCGHFFCDSCWSAHFASQLQIGVSSGIECMNC-------NLLVGETVVLNVLKGGK-LREKFINFLFNDQIKTFSKLRWCPGINC--GFLVR-AEEPAAKRVICSKCNTMFCFSCGEKYHAPTDCATIRKWLTKCEDDSETANYITANTKDCPECGSCIE-KNGGCNHMQCIKCKHDFCWMCMGTWKSHGSEYYECSRYKSNPNIANESAGIQAREALKKYLFYFERWQNHADSLKKEAE--TQRKINQK 371
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO31527 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXP1])

HSP 1 Score: 48.1358 bits (113), Expect = 3.832e-6
Identity = 51/222 (22.97%), Postives = 88/222 (39.64%), Query Frame = 2 
Query:  440 CPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP--SCPSRMTKI------DRNI--HFLSFRNLIDSDKKLKNLFHDKL--RDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDL------MKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCL 1051
            C +CL +  LS  +    C  + C  CL+  + E + T+      CP  +C   +++       D  I   ++ F+   D +  +K   +  +  R + LK       C  +        +  K+  I CE C    C  C+  WH   +CE++     K D  L         +     +CP+C+V    +  GC  + C  C+ +FC  C + FR  + L
Sbjct:    8 CYVCLTFVALSESVLSECCGGKTCKECLRYHIEEKV-TQGIVQIICPFENCDGVLSETVIKEISDEEIWKKYVKFKVDRDPNSSVKTCPNCAMVFRKQPLKEQDQQNVCATKSKKKEKKEQISKDCKIVCEECKFVWCFDCHAPWHYGISCEKF----CKGDTSLRIWARNRGALTRNATQCPKCRVYIQRI-SGCDSMACSRCQTQFCYRCGRHFRGNRFL 223
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000016758.2 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:101174057])

HSP 1 Score: 164.851 bits (416), Expect = 2.501e-43
Identity = 104/330 (31.52%), Postives = 155/330 (46.97%), Query Frame = 2 
Query:  416 IINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKK------LKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKK--VEFHA-PQKLNVKRCPTILTDKNYKDFKCNKNCY-----KNVGLCEDHYKEYLCLLIFSYDLDVSSI 1339
            I  +L  +CPICL  FP S M ++TSC C  CH C  +     I  K   D  CP C      I+      S+ + +D   +      +  LFH KL +  L     F WC +  CT+GF I +  +  + C  CH   C  C   W   H++ +CE++Q     NDP+     L   ++   I C +C  Q+ L KGGCMH  C  CR +FCS C   + +  C    C+  GLHAHHP +C ++ RD D   L ++L++  V ++  P          ++  K+    + +  C         GLC+ HY+EYL  LI ++ LD + +
Sbjct:  739 IRRLLNNECPICLSIFPRSKMQSLTSCQCSVCHECFSQHFTVAIRDKHIRDMVCPVCGE--PDINDPQQLDSYFSTLDIQLRDCLLHDVYELFHKKLTEHTLMKDPKFLWCCH--CTSGF-INDGDQLKVTCLSCHKSFCAKCKKAWEPQHQDVSCEQFQQWKRDNDPEYQKQGLAGYLRDNGITCLQCGFQYALTKGGCMHFTCSQCRYQFCSGCNNPYHKTACKAPQCSYPGLHAHHPRDCLFYLRDWDAARLQALLQRNRVGYNTDPSSGAQTDACGVMEQKDEGGQQVDSPCGVQTQPGQAGLCDKHYREYLVSLINAHSLDPAPL 1063
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000005329.2 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:101155382])

HSP 1 Score: 162.54 bits (410), Expect = 1.420e-42
Identity = 111/351 (31.62%), Postives = 163/351 (46.44%), Query Frame = 2 
Query:  353 SKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILK--KVEFHA--PQKLNVKRCPTILT---DKNYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
            S   S+E + + + E    E I  +L ++CPICL  FP S M ++TSC C  C  C ++     +  K   D  CP C      I+   H  S+ + +D       + ++  LFH KL ++ L     F WC +  C+ GF I +  +  + C  C +  C  C   W   H   +CE+YQ    +NDP+     L   ++   I CP C+ Q+ L KGGCMH  C  CR +FCS C   F    C    C+ +GLHAHHP +C ++ RD +   L ++L+   V+F+   P       C  I          D  C          LCE HY+EYL  LI S+ +D + +
Sbjct:  686 SAPYSLEDVVQAVRESHDREFIRRVLAKECPICLSVFPHSKMQSLTSCQCSVCCDCFQQHFTIAVRDKHIRDMVCPVC--WEPDINDPEHLNSYFSTLDIQLRECLEPEVYELFHKKLTEQALIKDPKFLWCCH--CSYGF-IYDGDQLKVTCFQCRNSFCAQCKKPWEPQHEGLSCEQYQTWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALSKGGCMHFCCSQCRYQFCSGCNNPF-HTTCAVDGCSVSGLHAHHPRDCLFYLRDWEPARLQALLQNNGVDFNTEPPPGTQTGLCGVIEQKDEGGQQSDAACGAQTQSGHAALCEKHYREYLVSLINSHSIDPAPL 1030
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000044452.1 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:101155382])

HSP 1 Score: 162.54 bits (410), Expect = 1.420e-42
Identity = 111/351 (31.62%), Postives = 163/351 (46.44%), Query Frame = 2 
Query:  353 SKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILK--KVEFHA--PQKLNVKRCPTILT---DKNYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
            S   S+E + + + E    E I  +L ++CPICL  FP S M ++TSC C  C  C ++     +  K   D  CP C      I+   H  S+ + +D       + ++  LFH KL ++ L     F WC +  C+ GF I +  +  + C  C +  C  C   W   H   +CE+YQ    +NDP+     L   ++   I CP C+ Q+ L KGGCMH  C  CR +FCS C   F    C    C+ +GLHAHHP +C ++ RD +   L ++L+   V+F+   P       C  I          D  C          LCE HY+EYL  LI S+ +D + +
Sbjct:  686 SAPYSLEDVVQAVRESHDREFIRRVLAKECPICLSVFPHSKMQSLTSCQCSVCCDCFQQHFTIAVRDKHIRDMVCPVC--WEPDINDPEHLNSYFSTLDIQLRECLEPEVYELFHKKLTEQALIKDPKFLWCCH--CSYGF-IYDGDQLKVTCFQCRNSFCAQCKKPWEPQHEGLSCEQYQTWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALSKGGCMHFCCSQCRYQFCSGCNNPF-HTTCAVDGCSVSGLHAHHPRDCLFYLRDWEPARLQALLQNNGVDFNTEPPPGTQTGLCGVIEQKDEGGQQSDAACGAQTQSGHAALCEKHYREYLVSLINSHSIDPAPL 1030
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000028853.1 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:101155382])

HSP 1 Score: 162.54 bits (410), Expect = 1.555e-42
Identity = 111/351 (31.62%), Postives = 163/351 (46.44%), Query Frame = 2 
Query:  353 SKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDS------DKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPD-----LMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILK--KVEFHA--PQKLNVKRCPTILT---DKNYKDFKCNKNCYKN-VGLCEDHYKEYLCLLIFSYDLDVSSI 1339
            S   S+E + + + E    E I  +L ++CPICL  FP S M ++TSC C  C  C ++     +  K   D  CP C      I+   H  S+ + +D       + ++  LFH KL ++ L     F WC +  C+ GF I +  +  + C  C +  C  C   W   H   +CE+YQ    +NDP+     L   ++   I CP C+ Q+ L KGGCMH  C  CR +FCS C   F    C    C+ +GLHAHHP +C ++ RD +   L ++L+   V+F+   P       C  I          D  C          LCE HY+EYL  LI S+ +D + +
Sbjct:  686 SAPYSLEDVVQAVRESHDREFIRRVLAKECPICLSVFPHSKMQSLTSCQCSVCCDCFQQHFTIAVRDKHIRDMVCPVC--WEPDINDPEHLNSYFSTLDIQLRECLEPEVYELFHKKLTEQALIKDPKFLWCCH--CSYGF-IYDGDQLKVTCFQCRNSFCAQCKKPWEPQHEGLSCEQYQTWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALSKGGCMHFCCSQCRYQFCSGCNNPF-HTTCAVDGCSVSGLHAHHPRDCLFYLRDWEPARLQALLQNNGVDFNTEPPPGTQTGLCGVIEQKDEGGQQSDAACGAQTQSGHAALCEKHYREYLVSLINSHSIDPAPL 1030
[Close]
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: si:dkey-181m9.8 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:101162956])

HSP 1 Score: 134.035 bits (336), Expect = 3.530e-33
Identity = 105/410 (25.61%), Postives = 166/410 (40.49%), Query Frame = 2 
Query:  161 GFINCKSCYKNXXXXXXXXXXXXXNGDYKITSSNLVPSLRAKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIH-FLSFRNLIDSD------KKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPM-IECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLMKVMK-TIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKC--LHRNCTNTGLHAHHPSNCQYFTRDNDINELNSIL----------KKVEFHAPQKLNVKRCPTI--LTDKNYKDFKCNKNCYKNV-GLCEDHYKEYLCLLI 1309
            GF   K  +K      T         D+   ++ L P+ +A V L +  L  ++F         +  +    LNK  S        +  L   CPIC +    S ++ MT CSC  C +C   + +  I  +      CP C     +    +     + NL+D+       + +  LF  KLRD  L+   +F WC    C+  F I ++ E + ++C  C    C  C   W   H+  +CE+++    +N  D       +  I+CP C+  F L +GGC+H  C  C+ +FC  C +TF  G        C   GLHAHHP +C +  RD  ++ L  +L          K     +        C  +    D + ++  C +   +   G C+ HYKE L  LI
Sbjct:  328 GFTAPKVTFKGAQDSATAGS----GADFSKLAARL-PADQAAVFLALMTLQGQSFSP-------ADALEAVQLNKDFS------SALKFLTHTCPICHEQVSFSKIVTMTHCSCFLCQVCFTAFFSVAIKERSVDQLVCPQCGKPEVRAQGGLEDATEYFNLLDTQIRHYLPRDIHELFQRKLRDRTLREMPDFCWC--AHCS--FGILHEAERLRMDCPSCKKSTCSRCRSPWAPQHQRLSCEQFKAWQEQNQLDHHGSTPISNSIECPGCRSVFSLARGGCLHFTCTQCQHQFCGGCARTFTAGSACGFSAECGTKGLHAHHPRDCLFHLRDWSVSRLLLLLQHYRISPAWIKPASGSSSDGTQTAVCSVLELRDDGSKREEPCGRPTPQGFQGYCQLHYKERLVELI 715
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000015149.1 (SMESG000015149.1)

HSP 1 Score: 806.979 bits (2083), Expect = 0.000e+0
Identity = 411/416 (98.80%), Postives = 413/416 (99.28%), Query Frame = 2 
Query:  110 MTENFWICHWCDTRNDSGFINCKSCYKNXXXXXXXXXXXXXNGDYKITSSNLVPSLRAKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKNYKDFKCNKNCYKNVGLCEDHYKEYLCLLIFSYDLDVSSISKRFIN 1357
            MTENFWICHWCDTRNDSGFINCKSCYKNILTIETIIQR+ILNGDYKITS NLVPSLRAKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCP CPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQK NVKRCPTILTDKNYKDFKCNKNCYKNVGLCEDHYKEYLCLLIF+YDLDVSSISKRFIN
Sbjct:    1 MTENFWICHWCDTRNDSGFINCKSCYKNILTIETIIQRVILNGDYKITSLNLVPSLRAKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPRCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKWHRNETCEEYQFRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKPNVKRCPTILTDKNYKDFKCNKNCYKNVGLCEDHYKEYLCLLIFNYDLDVSSISKRFIN 416
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000015148.1 (SMESG000015148.1)

HSP 1 Score: 239.965 bits (611), Expect = 3.068e-74
Identity = 126/361 (34.90%), Postives = 187/361 (51.80%), Query Frame = 2 
Query:  281 AKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS-RMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKNYKDFKCNKNCYKNVGLCEDHYKEYLCLLIFSYDLDVSSISKRF 1351
              +DLL   + + +   YL+Q+     + +  L + + + +  +  +N L + C IC   +P+  M    +C  E C  C+ +WL E I  K    W CP CP      +++N+H+   ++ +  +  L N+F  KL  E+L  S NF WC NE CTNGFD     +  I C  C + +C+ CN  W   H N+TC+E++   LKNDP+L K++  I I+CP C +++ L  GGC+H  CK C  +FC  C + F   KC   NC    +H+HHP NC YF RD    EL  +LK  ++   Q    K C  ++T++  KD  CNK+      LCE HYKEYL   I  Y +D +     F
Sbjct:    7 GPLDLLREFMRDMSLGEYLRQECPDGSVKLHHLKQAMIDQISIDGAMNFLKKSCEICCFDYPIPEMRGFITCQHELCKDCMSQWLAETIEVKFPCKWSCPCCPDDNYINVNKNLHYAQLKDFLTDNVSLINIFESKLLQEQLMKSDNFHWCANEACTNGFDAEGIDK--IICPSCKTQMCVKCNQMWKEAHENKTCQEFELWMLKNDPNLSKLLNDIGIECPNCTMRYALAPGGCIHFDCKACGTKFCGGCYQLFV-NKCNKPNCHMMNVHSHHPRNCLYFLRDYTHTELEKMLKDFDYPKLQGKPEKMCQLMITNEQPKDAACNKDVCGTTALCEQHYKEYLVQFINRYKIDPADFVDSF 364
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000015148.1 (SMESG000015148.1)

HSP 1 Score: 239.965 bits (611), Expect = 3.867e-74
Identity = 126/361 (34.90%), Postives = 187/361 (51.80%), Query Frame = 2 
Query:  281 AKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS-RMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKNYKDFKCNKNCYKNVGLCEDHYKEYLCLLIFSYDLDVSSISKRF 1351
              +DLL   + + +   YL+Q+     + +  L + + + +  +  +N L + C IC   +P+  M    +C  E C  C+ +WL E I  K    W CP CP      +++N+H+   ++ +  +  L N+F  KL  E+L  S NF WC NE CTNGFD     +  I C  C + +C+ CN  W   H N+TC+E++   LKNDP+L K++  I I+CP C +++ L  GGC+H  CK C  +FC  C + F   KC   NC    +H+HHP NC YF RD    EL  +LK  ++   Q    K C  ++T++  KD  CNK+      LCE HYKEYL   I  Y +D +     F
Sbjct:   10 GPLDLLREFMRDMSLGEYLRQECPDGSVKLHHLKQAMIDQISIDGAMNFLKKSCEICCFDYPIPEMRGFITCQHELCKDCMSQWLAETIEVKFPCKWSCPCCPDDNYINVNKNLHYAQLKDFLTDNVSLINIFESKLLQEQLMKSDNFHWCANEACTNGFDAEGIDK--IICPSCKTQMCVKCNQMWKEAHENKTCQEFELWMLKNDPNLSKLLNDIGIECPNCTMRYALAPGGCIHFDCKACGTKFCGGCYQLFV-NKCNKPNCHMMNVHSHHPRNCLYFLRDYTHTELEKMLKDFDYPKLQGKPEKMCQLMITNEQPKDAACNKDVCGTTALCEQHYKEYLVQFINRYKIDPADFVDSF 367
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000015148.1 (SMESG000015148.1)

HSP 1 Score: 240.35 bits (612), Expect = 7.625e-74
Identity = 126/361 (34.90%), Postives = 187/361 (51.80%), Query Frame = 2 
Query:  281 AKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS-RMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKNYKDFKCNKNCYKNVGLCEDHYKEYLCLLIFSYDLDVSSISKRF 1351
              +DLL   + + +   YL+Q+     + +  L + + + +  +  +N L + C IC   +P+  M    +C  E C  C+ +WL E I  K    W CP CP      +++N+H+   ++ +  +  L N+F  KL  E+L  S NF WC NE CTNGFD     +  I C  C + +C+ CN  W   H N+TC+E++   LKNDP+L K++  I I+CP C +++ L  GGC+H  CK C  +FC  C + F   KC   NC    +H+HHP NC YF RD    EL  +LK  ++   Q    K C  ++T++  KD  CNK+      LCE HYKEYL   I  Y +D +     F
Sbjct:   46 GPLDLLREFMRDMSLGEYLRQECPDGSVKLHHLKQAMIDQISIDGAMNFLKKSCEICCFDYPIPEMRGFITCQHELCKDCMSQWLAETIEVKFPCKWSCPCCPDDNYINVNKNLHYAQLKDFLTDNVSLINIFESKLLQEQLMKSDNFHWCANEACTNGFDAEGIDK--IICPSCKTQMCVKCNQMWKEAHENKTCQEFELWMLKNDPNLSKLLNDIGIECPNCTMRYALAPGGCIHFDCKACGTKFCGGCYQLFV-NKCNKPNCHMMNVHSHHPRNCLYFLRDYTHTELEKMLKDFDYPKLQGKPEKMCQLMITNEQPKDAACNKDVCGTTALCEQHYKEYLVQFINRYKIDPADFVDSF 403
[Close]
BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000015148.1 (SMESG000015148.1)

HSP 1 Score: 239.58 bits (610), Expect = 2.498e-73
Identity = 126/361 (34.90%), Postives = 187/361 (51.80%), Query Frame = 2 
Query:  281 AKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVSEDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKPTTDWYCPSCPS-RMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKSSKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKW---HRNETCEEYQFRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEFCSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKVEFHAPQKLNVKRCPTILTDKNYKDFKCNKNCYKNVGLCEDHYKEYLCLLIFSYDLDVSSISKRF 1351
              +DLL   + + +   YL+Q+     + +  L + + + +  +  +N L + C IC   +P+  M    +C  E C  C+ +WL E I  K    W CP CP      +++N+H+   ++ +  +  L N+F  KL  E+L  S NF WC NE CTNGFD     +  I C  C + +C+ CN  W   H N+TC+E++   LKNDP+L K++  I I+CP C +++ L  GGC+H  CK C  +FC  C + F   KC   NC    +H+HHP NC YF RD    EL  +LK  ++   Q    K C  ++T++  KD  CNK+      LCE HYKEYL   I  Y +D +     F
Sbjct:   71 GPLDLLREFMRDMSLGEYLRQECPDGSVKLHHLKQAMIDQISIDGAMNFLKKSCEICCFDYPIPEMRGFITCQHELCKDCMSQWLAETIEVKFPCKWSCPCCPDDNYINVNKNLHYAQLKDFLTDNVSLINIFESKLLQEQLMKSDNFHWCANEACTNGFDAEGIDK--IICPSCKTQMCVKCNQMWKEAHENKTCQEFELWMLKNDPNLSKLLNDIGIECPNCTMRYALAPGGCIHFDCKACGTKFCGGCYQLFV-NKCNKPNCHMMNVHSHHPRNCLYFLRDYTHTELEKMLKDFDYPKLQGKPEKMCQLMITNEQPKDAACNKDVCGTTALCEQHYKEYLVQFINRYKIDPADFVDSF 428
The following BLAST results are available for this feature:
BLAST of RING-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RNF314.123e-3929.08ring finger protein 31 [Source:HGNC Symbol;Acc:HGN... [more]
RNF314.123e-3929.08ring finger protein 31 [Source:HGNC Symbol;Acc:HGN... [more]
RNF314.855e-3929.08ring finger protein 31 [Source:HGNC Symbol;Acc:HGN... [more]
RNF314.855e-3929.08ring finger protein 31 [Source:HGNC Symbol;Acc:HGN... [more]
AL136295.106.412e-3929.08novel transcript[more]
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BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
C17H11.65.415e-1225.70RBR-type E3 ubiquitin transferase [Source:UniProt... [more]
C17H11.65.415e-1225.70RBR-type E3 ubiquitin transferase [Source:UniProt... [more]
C17H11.65.832e-1225.70RBR-type E3 ubiquitin transferase [Source:UniProt... [more]
C17H11.65.832e-1225.70RBR-type E3 ubiquitin transferase [Source:UniProt... [more]
C17H11.65.975e-1225.70RBR-type E3 ubiquitin transferase [Source:UniProt... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LUBEL7.500e-4730.24gene:FBgn0031857 transcript:FBtr0331220[more]
LUBEL7.522e-4730.24gene:FBgn0031857 transcript:FBtr0331216[more]
LUBEL9.201e-4730.24gene:FBgn0031857 transcript:FBtr0331221[more]
LUBEL9.229e-4730.24gene:FBgn0031857 transcript:FBtr0331218[more]
ari-12.952e-1024.30gene:FBgn0017418 transcript:FBtr0089508[more]
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BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-181m9.84.199e-4030.42si:dkey-181m9.8 [Source:ZFIN;Acc:ZDB-GENE-070912-3... [more]
FO834800.14.634e-3832.37E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen... [more]
FO834800.27.862e-3432.37E3 ubiquitin-protein ligase RNF31-like [Source:NCB... [more]
rnf144aa3.040e-1324.24ring finger protein 144aa [Source:NCBI gene;Acc:57... [more]
rnf144ab4.282e-1325.00ring finger protein 144ab [Source:NCBI gene;Acc:43... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf311.052e-3529.64ring finger protein 31 [Source:NCBI gene;Acc:10003... [more]
rnf311.150e-3529.64ring finger protein 31 [Source:NCBI gene;Acc:10003... [more]
rnf312.029e-3529.64ring finger protein 31 [Source:NCBI gene;Acc:10003... [more]
rnf312.256e-3529.36ring finger protein 31 [Source:NCBI gene;Acc:10003... [more]
rnf311.908e-3428.88ring finger protein 31 [Source:NCBI gene;Acc:10003... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rnf316.686e-4029.51ring finger protein 31 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf316.799e-4029.51ring finger protein 31 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf144a5.868e-1324.56ring finger protein 144A [Source:MGI Symbol;Acc:MG... [more]
Rnf144a5.868e-1324.56ring finger protein 144A [Source:MGI Symbol;Acc:MG... [more]
Rnf316.861e-1339.51ring finger protein 31 [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8IPJ3|LUBEL_DROME7.540e-4630.24E3 ubiquitin-protein ligase lubel OS=Drosophila me... [more]
sp|Q924T7|RNF31_MOUSE4.756e-3929.51E3 ubiquitin-protein ligase RNF31 OS=Mus musculus ... [more]
sp|Q96EP0|RNF31_HUMAN3.079e-3829.08E3 ubiquitin-protein ligase RNF31 OS=Homo sapiens ... [more]
sp|A4IIY1|R144A_XENTR1.510e-1225.33Probable E3 ubiquitin-protein ligase RNF144A OS=Xe... [more]
sp|Q5RFV4|R1441_DANRE2.295e-1224.24Probable E3 ubiquitin-protein ligase RNF144A-A OS=... [more]
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BLAST of RING-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2T7NIC01.089e-5132.98Uncharacterized protein OS=Pomacea canaliculata OX... [more]
A0A084VI461.359e-4832.56AGAP007788-PA-like protein OS=Anopheles sinensis O... [more]
A0A182X1H84.489e-4831.96RING-type domain-containing protein OS=Anopheles q... [more]
A0A182IEF94.491e-4831.96RING-type domain-containing protein OS=Anopheles a... [more]
A0A433U6J94.974e-4831.59RanBP2-type domain-containing protein (Fragment) O... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000014446.28.979e-4431.21ring finger protein 31 [Source:NCBI gene;Acc:10303... [more]
ENSAMXT00000018785.24.369e-4231.50E3 ubiquitin-protein ligase RNF31-like [Source:NCB... [more]
si:dkey-181m9.88.545e-3830.54E3 ubiquitin-protein ligase RNF31-like [Source:NCB... [more]
rnf144aa1.513e-1425.33probable E3 ubiquitin-protein ligase RNF144A-A [So... [more]
rnf144aa3.229e-1425.33probable E3 ubiquitin-protein ligase RNF144A-A [So... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000006434.11.839e-3133.88pep scaffold:Pmarinus_7.0:GL492086:439:5313:1 gene... [more]
ENSPMAT00000007741.11.453e-1222.87pep scaffold:Pmarinus_7.0:GL477427:676:25209:1 gen... [more]
rnf19a2.012e-1025.41ring finger protein 19A, RBR E3 ubiquitin protein ... [more]
ENSPMAT00000006333.11.019e-921.82pep scaffold:Pmarinus_7.0:GL479789:448:31336:-1 ge... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
HEL12.872e-825.17RING finger ubiquitin ligase (E3); involved in ubi... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO464751.461e-4529.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO374371.764e-1125.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO366161.538e-926.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO480964.834e-922.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO315273.832e-622.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000016758.22.501e-4331.52E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen... [more]
ENSORLT00000005329.21.420e-4231.62E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen... [more]
ENSORLT00000044452.11.420e-4231.62E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen... [more]
ENSORLT00000028853.11.555e-4231.62E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen... [more]
si:dkey-181m9.83.530e-3325.61E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen... [more]
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BLAST of RING-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000015149.10.000e+098.80SMESG000015149.1[more]
SMESG000015148.13.068e-7434.90SMESG000015148.1[more]
SMESG000015148.13.867e-7434.90SMESG000015148.1[more]
SMESG000015148.17.625e-7434.90SMESG000015148.1[more]
SMESG000015148.12.498e-7334.90SMESG000015148.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023752 ID=SMED30023752|Name=RING-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1437bp
CCTACATGTGATTCTTAGTTTATGATATTATTTAATTTAGATGAACATGT
TTTTTAAACATCCTTATTTTTATCAATTTTATTTTGCATTTTTCTATTAT
TGAGAATTTATGACAGAAAACTTCTGGATATGCCACTGGTGTGATACTCG
CAATGATTCTGGCTTTATAAATTGCAAAAGCTGCTATAAAAACATATTAA
CAATAGAAACCATTATTCAAAGAATTATACTAAATGGAGATTATAAAATC
ACATCATCGAACTTAGTTCCAAGTCTTCGTGCAAAAGTAGATTTGTTAAT
ATCTGTTCTTCACAATGAAAACTTTAAGTCATATTTAAAACAAAAACTTA
TTAGTAAAGAGATAAGTATTGAGCTTTTGAATAAAACGCTCTCAGAATTC
GTTGTTTCGGAGGATATCATAAATATTTTGATGCGACAATGTCCAATCTG
TCTTGATTATTTCCCATTGTCAAATATGATAAATATGACTTCCTGCAGTT
GTGAATTTTGTCATATTTGTTTAAAAGAGTGGTTAAATGAAAACATACCT
ACAAAACCAACCACTGATTGGTACTGTCCAAGCTGTCCAAGTCGAATGAC
AAAAATAGACAGAAATATACATTTTCTCAGCTTTCGAAATCTAATTGATT
CAGATAAAAAGCTTAAGAATTTATTTCATGACAAACTCCGTGATGAGAAA
TTAAAATCCAGTAAAAATTTTCGATGGTGCCCAAATGAAAAATGTACGAA
TGGATTTGACATAAGAAATAAGAAAGAGCCGATGATTGAATGTGAATATT
GTCATTCGTTCGTGTGTTTACATTGCAATGTAAAGTGGCATAGAAACGAA
ACTTGTGAAGAATATCAATTTAGAACATTGAAAAATGATCCAGATTTAAT
GAAAGTTATGAAGACAATTGAAATAAAATGCCCCAGATGTCAAGTTCAAT
TTGATCTTGTTAAAGGGGGATGCATGCATTTAAAATGCAAAAACTGTCGT
ATTGAATTTTGTAGTTGTTGTAAGAAAACATTTCGACAGGGTAAATGCTT
ACATAGAAATTGCACTAATACTGGTCTTCATGCACATCATCCAAGCAATT
GCCAATATTTTACAAGAGATAATGATATTAACGAATTAAATTCCATTTTA
AAAAAGGTGGAATTTCATGCGCCACAGAAGCTAAATGTCAAAAGATGTCC
TACTATCCTTACTGATAAAAATTACAAGGATTTCAAATGCAATAAAAATT
GCTACAAAAATGTTGGATTGTGCGAGGACCATTATAAAGAGTATTTGTGC
TTGTTAATTTTCAGTTATGATCTTGATGTTTCTTCAATATCGAAGCGATT
CATAAACTAGTGCTAAAGGAGTGATAATTTAATATTTCACTTTTAAATTA
ATTAATTTCAGAGTTAAATTAGTGGACTGGTGGAATA
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protein sequence of SMED30023752-orf-1

>SMED30023752-orf-1 ID=SMED30023752-orf-1|Name=SMED30023752-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=417bp
MTENFWICHWCDTRNDSGFINCKSCYKNILTIETIIQRIILNGDYKITSS
NLVPSLRAKVDLLISVLHNENFKSYLKQKLISKEISIELLNKTLSEFVVS
EDIINILMRQCPICLDYFPLSNMINMTSCSCEFCHICLKEWLNENIPTKP
TTDWYCPSCPSRMTKIDRNIHFLSFRNLIDSDKKLKNLFHDKLRDEKLKS
SKNFRWCPNEKCTNGFDIRNKKEPMIECEYCHSFVCLHCNVKWHRNETCE
EYQFRTLKNDPDLMKVMKTIEIKCPRCQVQFDLVKGGCMHLKCKNCRIEF
CSCCKKTFRQGKCLHRNCTNTGLHAHHPSNCQYFTRDNDINELNSILKKV
EFHAPQKLNVKRCPTILTDKNYKDFKCNKNCYKNVGLCEDHYKEYLCLLI
FSYDLDVSSISKRFIN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0010286heat acclimation
GO:0050829defense response to Gram-negative bacterium
GO:0061059positive regulation of peptidoglycan recognition protein signaling pathway
GO:0097039protein linear polyubiquitination
GO:0016567protein ubiquitination
Vocabulary: molecular function
TermDefinition
GO:0016740transferase activity
GO:0036435K48-linked polyubiquitin binding
GO:0061630ubiquitin protein ligase activity
GO:0070530K63-linked polyubiquitin binding
GO:1990450linear polyubiquitin binding
GO:0008270zinc ion binding
GO:0005515protein binding
GO:0004842ubiquitin-protein transferase activity
GO:0016874ligase activity
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR041031RNF31_C
IPR026254RNF31-like
IPR002867IBR_dom
IPR001841Znf_RING
IPR013083Znf_RING/FYVE/PHD
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
GO:0071797LUBAC complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001841Zinc finger, RING-typeSMARTSM00184ring_2coord: 111..159
e-value: 0.0074
score: 25.5
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 111..159
score: 10.439
IPR002867IBR domainSMARTSM00647ibrneu5coord: 187..249
e-value: 2.3E-8
score: 43.8
IPR002867IBR domainPFAMPF01485IBRcoord: 189..249
e-value: 1.2E-9
score: 38.2
IPR041031RNF31, C-terminalPFAMPF18091E3_UbLigase_RBRcoord: 351..407
e-value: 9.9E-6
score: 25.6
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 107..196
e-value: 2.0E-10
score: 42.5
IPR026254E3 ubiquitin-protein ligase RNF31-likePANTHERPTHR16004RING FINGER PROTEIN 31-RELATEDcoord: 100..408
NoneNo IPR availablePROSITEPS51873TRIADcoord: 107..322
score: 20.845
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 110..164
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 190..253