Cold shock domain protein

Overview
NameCold shock domain protein
Smed IDSMED30023729
Length (bp)976
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cold shock domain protein (SMED30023729) t-SNE clustered cells

Violin plots show distribution of expression levels for Cold shock domain protein (SMED30023729) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cold shock domain protein (SMED30023729) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cold shock domain protein (SMED30023729) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023729

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30023729SMESG000073546.1 dd_Smed_v4_392_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30023729SMESG000073546.1 dd_Smed_v4_392_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30023729SMESG000073546.1 dd_Smed_v4_392_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30023729SMESG000073546.1 dd_Smed_v4_392_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023729SMESG000073546.1 dd_Smed_v4_392_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30023729SMESG000073546.1 dd_Smed_v4_392_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cold shock domain protein vs. Ensembl Human
Match: YBX1 (Y-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8014])

HSP 1 Score: 82.0333 bits (201), Expect = 3.786e-17
Identity = 43/87 (49.43%), Postives = 53/87 (60.92%), Query Frame = 1 
Query:   73 DYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            D  +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP G  V G K
Sbjct:   51 DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSK 137
[Close]
BLAST of Cold shock domain protein vs. Ensembl Human
Match: YBX2 (Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948])

HSP 1 Score: 82.4185 bits (202), Expect = 4.602e-17
Identity = 46/98 (46.94%), Postives = 57/98 (58.16%), Query Frame = 1 
Query:   67 MTDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRS 348
              D  +   +V G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP GG  V G  Y PN  +S
Sbjct:   84 QADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGP-GGVPVKGSRYAPNRRKS 180
[Close]
BLAST of Cold shock domain protein vs. Ensembl Human
Match: YBX2 (Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948])

HSP 1 Score: 82.4185 bits (202), Expect = 4.602e-17
Identity = 46/98 (46.94%), Postives = 57/98 (58.16%), Query Frame = 1 
Query:   67 MTDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRS 348
              D  +   +V G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP GG  V G  Y PN  +S
Sbjct:   84 QADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEATNVTGP-GGVPVKGSRYAPNRRKS 180
[Close]
BLAST of Cold shock domain protein vs. Ensembl Human
Match: YBX3 (Y-box binding protein 3 [Source:HGNC Symbol;Acc:HGNC:2428])

HSP 1 Score: 82.0333 bits (201), Expect = 5.797e-17
Identity = 42/84 (50.00%), Postives = 53/84 (63.10%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GPDG  V G +
Sbjct:   86 VLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSR 169
[Close]
BLAST of Cold shock domain protein vs. Ensembl Human
Match: YBX3 (Y-box binding protein 3 [Source:HGNC Symbol;Acc:HGNC:2428])

HSP 1 Score: 80.4925 bits (197), Expect = 1.182e-16
Identity = 42/84 (50.00%), Postives = 53/84 (63.10%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GPDG  V G +
Sbjct:   86 VLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSR 169
[Close]
BLAST of Cold shock domain protein vs. Ensembl Celegans
Match: cey-1 (C. Elegans Y-box [Source:UniProtKB/TrEMBL;Acc:O62213])

HSP 1 Score: 94.3597 bits (233), Expect = 9.058e-23
Identity = 47/88 (53.41%), Postives = 58/88 (65.91%), Query Frame = 1 
Query:   70 TDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSN----SLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
             D  +K +KV G VKWFN K+GYGFI +     D+FVH ++I   N N    SL D EEV+FD++EG KGLEA +V GPDGG V G K
Sbjct:   12 ADKPVKATKVKGTVKWFNVKNGYGFINRTDTNEDIFVHQTAIINNNPNKYLRSLGDNEEVMFDIVEGSKGLEAASVTGPDGGPVQGSK 99
[Close]
BLAST of Cold shock domain protein vs. Ensembl Celegans
Match: cey-4 (C. Elegans Y-box [Source:UniProtKB/TrEMBL;Acc:G5EDV3])

HSP 1 Score: 77.0258 bits (188), Expect = 6.261e-16
Identity = 39/88 (44.32%), Postives = 56/88 (63.64%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDV---DGADVFVHHSSITATNS-----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            + E+ V GHVKWF+ +  YGF+ +D    +  D FVH ++IT +++      +L D E V+FD++EG KG EA NV GPDG NV G +
Sbjct:   84 VIETGVKGHVKWFSVRGRYGFVARDKPTDENEDFFVHQTAITKSSTIKFYLRTLDDDEPVVFDIVEGLKGPEAANVTGPDGENVRGSR 171
[Close]
BLAST of Cold shock domain protein vs. Ensembl Celegans
Match: cey-4 (C. Elegans Y-box [Source:UniProtKB/TrEMBL;Acc:G5EDV3])

HSP 1 Score: 77.0258 bits (188), Expect = 6.261e-16
Identity = 39/88 (44.32%), Postives = 56/88 (63.64%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDV---DGADVFVHHSSITATNS-----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            + E+ V GHVKWF+ +  YGF+ +D    +  D FVH ++IT +++      +L D E V+FD++EG KG EA NV GPDG NV G +
Sbjct:   84 VIETGVKGHVKWFSVRGRYGFVARDKPTDENEDFFVHQTAITKSSTIKFYLRTLDDDEPVVFDIVEGLKGPEAANVTGPDGENVRGSR 171
[Close]
BLAST of Cold shock domain protein vs. Ensembl Celegans
Match: cey-2 (C. Elegans Y-box [Source:UniProtKB/TrEMBL;Acc:P91306])

HSP 1 Score: 73.1738 bits (178), Expect = 1.242e-14
Identity = 34/80 (42.50%), Postives = 50/80 (62.50%), Query Frame = 1 
Query:   97 VTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSN-----SLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            + G VKW++    YGFI ++    D+FVH ++I  + +      +L D EEVLFD++EG  G EA NV GP+G NV+G +
Sbjct:   66 LQGKVKWYSVLRRYGFISRNDGEKDIFVHQTAIAKSATEKFYLRTLGDDEEVLFDLVEGKNGPEAANVTGPNGDNVIGSR 145
[Close]
BLAST of Cold shock domain protein vs. Ensembl Celegans
Match: cey-3 (C. Elegans Y-box [Source:UniProtKB/TrEMBL;Acc:P91398])

HSP 1 Score: 70.8626 bits (172), Expect = 6.808e-14
Identity = 36/80 (45.00%), Postives = 50/80 (62.50%), Query Frame = 1 
Query:   97 VTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSN-----SLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            + G VKW++    YGFI +     DVFVH ++I+ +++      +LAD EEVLFD+++G  G EA NV GP G NV G K
Sbjct:   64 LQGKVKWYSVLRRYGFISRSDGEKDVFVHQTAISKSDTEKFYLRTLADEEEVLFDLVDGKNGPEAANVTGPAGVNVSGSK 143
[Close]
BLAST of Cold shock domain protein vs. Ensembl Fly
Match: yps (gene:FBgn0022959 transcript:FBtr0076027)

HSP 1 Score: 80.8777 bits (198), Expect = 7.027e-17
Identity = 44/85 (51.76%), Postives = 53/85 (62.35%), Query Frame = 1 
Query:   79 DIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSN----SLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            ++  +KVTG VKWFN KSGYGFI ++    DVFVH S+I   N      S+ DGE V FDV+ G KG EA NV GP G  V G +
Sbjct:   56 EVIATKVTGTVKWFNVKSGYGFINRNDTREDVFVHQSAIARNNPKKAVRSVGDGEVVEFDVVIGEKGNEAANVTGPSGEPVRGSQ 140
[Close]
BLAST of Cold shock domain protein vs. Ensembl Fly
Match: yps (gene:FBgn0022959 transcript:FBtr0305992)

HSP 1 Score: 80.4925 bits (197), Expect = 7.997e-17
Identity = 44/85 (51.76%), Postives = 53/85 (62.35%), Query Frame = 1 
Query:   79 DIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSN----SLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            ++  +KVTG VKWFN KSGYGFI ++    DVFVH S+I   N      S+ DGE V FDV+ G KG EA NV GP G  V G +
Sbjct:   56 EVIATKVTGTVKWFNVKSGYGFINRNDTREDVFVHQSAIARNNPKKAVRSVGDGEVVEFDVVIGEKGNEAANVTGPSGEPVRGSQ 140
[Close]
BLAST of Cold shock domain protein vs. Ensembl Fly
Match: lin-28 (gene:FBgn0035626 transcript:FBtr0077090)

HSP 1 Score: 58.5362 bits (140), Expect = 5.638e-10
Identity = 40/117 (34.19%), Postives = 55/117 (47.01%), Query Frame = 1 
Query:  103 GHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGGPRNDFRNQPYSRNSGNGGQPRRDYDRQGE 453
            G  KWFN   G+GF+  +  G +VFVH S I  +   SL + EEV F+     +GLEA  V    GG+  G       + R+   R     +F N   S     G QP+R +  +GE
Sbjct:   41 GKCKWFNVAKGWGFLTPNDGGQEVFVHQSVIQMSGFRSLGEQEEVEFECQRTSRGLEATRVSSRHGGSCQGSTYRPRINRRTRRMRCYNCGEFANHIAS-ECALGPQPKRCHRCRGE 156
[Close]
BLAST of Cold shock domain protein vs. Ensembl Zebrafish
Match: ybx1 (Y box binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-000629-3])

HSP 1 Score: 83.1889 bits (204), Expect = 9.389e-18
Identity = 43/87 (49.43%), Postives = 53/87 (60.92%), Query Frame = 1 
Query:   73 DYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            D  +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP G  V G K
Sbjct:   31 DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSK 117
[Close]
BLAST of Cold shock domain protein vs. Ensembl Zebrafish
Match: ybx1 (Y box binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-000629-3])

HSP 1 Score: 83.1889 bits (204), Expect = 9.389e-18
Identity = 43/87 (49.43%), Postives = 53/87 (60.92%), Query Frame = 1 
Query:   73 DYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            D  +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP G  V G K
Sbjct:   31 DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSK 117
[Close]
BLAST of Cold shock domain protein vs. Ensembl Zebrafish
Match: ybx1 (Y box binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-000629-3])

HSP 1 Score: 82.8037 bits (203), Expect = 1.371e-17
Identity = 43/87 (49.43%), Postives = 53/87 (60.92%), Query Frame = 1 
Query:   73 DYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            D  +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP G  V G K
Sbjct:   31 DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSK 117
[Close]
BLAST of Cold shock domain protein vs. Ensembl Zebrafish
Match: LIN28A (si:ch1073-284b18.2 [Source:ZFIN;Acc:ZDB-GENE-110914-157])

HSP 1 Score: 57.3806 bits (137), Expect = 2.207e-9
Identity = 32/79 (40.51%), Postives = 41/79 (51.90%), Query Frame = 1 
Query:  100 TGHVKWFNTKSGYGFIKKDV-DGA------DVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVG 315
             G  KWFN + G+GF+  +  DG       DVFVH S +      SL +GE V F   +  KGLE+  V GP G + VG
Sbjct:   25 VGVCKWFNVRMGFGFLSMNTRDGVPLETPVDVFVHQSKLHMEGFRSLKEGESVEFTFKKSSKGLESVRVTGPGGAHCVG 103
[Close]
BLAST of Cold shock domain protein vs. Ensembl Zebrafish
Match: LIN28A (si:ch1073-284b18.2 [Source:ZFIN;Acc:ZDB-GENE-110914-157])

HSP 1 Score: 56.9954 bits (136), Expect = 2.477e-9
Identity = 32/79 (40.51%), Postives = 41/79 (51.90%), Query Frame = 1 
Query:  100 TGHVKWFNTKSGYGFIKKDV-DGA------DVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVG 315
             G  KWFN + G+GF+  +  DG       DVFVH S +      SL +GE V F   +  KGLE+  V GP G + VG
Sbjct:   27 VGVCKWFNVRMGFGFLSMNTRDGVPLETPVDVFVHQSKLHMEGFRSLKEGESVEFTFKKSSKGLESVRVTGPGGAHCVG 105
[Close]
BLAST of Cold shock domain protein vs. Ensembl Xenopus
Match: hmgcs1 (3-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:Xenbase;Acc:XB-GENE-942074])

HSP 1 Score: 86.6557 bits (213), Expect = 7.566e-19
Identity = 51/102 (50.00%), Postives = 61/102 (59.80%), Query Frame = 1 
Query:   91 SKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDN---RSNIRRGGPRN 375
            +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP GG  V G  Y  + N   R   RRG PRN
Sbjct:   35 TKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGP-GGVPVQGSKYAADRNHFRRYQRRRGPPRN 135
[Close]
BLAST of Cold shock domain protein vs. Ensembl Xenopus
Match: hmgcs1 (3-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:Xenbase;Acc:XB-GENE-942074])

HSP 1 Score: 84.3445 bits (207), Expect = 4.883e-18
Identity = 51/102 (50.00%), Postives = 61/102 (59.80%), Query Frame = 1 
Query:   91 SKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDN---RSNIRRGGPRN 375
            +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP GG  V G  Y  + N   R   RRG PRN
Sbjct:   43 TKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGP-GGVPVQGSKYAADRNHFRRYQRRRGPPRN 143
[Close]
BLAST of Cold shock domain protein vs. Ensembl Xenopus
Match: ybx3 (Y-box binding protein 3 [Source:NCBI gene;Acc:548572])

HSP 1 Score: 78.9518 bits (193), Expect = 1.908e-16
Identity = 40/84 (47.62%), Postives = 51/84 (60.71%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+ G KG EA NV GP G  V G +
Sbjct:   31 VLATKVQGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGEVVEFDVVAGEKGAEAANVTGPKGAPVQGSR 114
[Close]
BLAST of Cold shock domain protein vs. Ensembl Xenopus
Match: lin28b (lin-28 homolog B [Source:NCBI gene;Acc:100216028])

HSP 1 Score: 58.151 bits (139), Expect = 2.989e-9
Identity = 30/79 (37.97%), Postives = 39/79 (49.37%), Query Frame = 1 
Query:  100 TGHVKWFNTKSGYGFIKKDV-------DGADVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVG 315
            +GH KWFN + G+GFI           +  DVFVH S +      SL +GE V F   +  KG E+  V GP G   +G
Sbjct:   34 SGHCKWFNVRMGFGFISMTSREGSPLENPVDVFVHQSKLYMEGFRSLKEGEPVEFTFKKSSKGFESLRVTGPGGNPCLG 112
[Close]
BLAST of Cold shock domain protein vs. Ensembl Xenopus
Match: lin28b (lin-28 homolog B [Source:NCBI gene;Acc:100216028])

HSP 1 Score: 58.5362 bits (140), Expect = 3.222e-9
Identity = 30/79 (37.97%), Postives = 39/79 (49.37%), Query Frame = 1 
Query:  100 TGHVKWFNTKSGYGFIKKDV-------DGADVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVG 315
            +GH KWFN + G+GFI           +  DVFVH S +      SL +GE V F   +  KG E+  V GP G   +G
Sbjct:   58 SGHCKWFNVRMGFGFISMTSREGSPLENPVDVFVHQSKLYMEGFRSLKEGEPVEFTFKKSSKGFESLRVTGPGGNPCLG 136
[Close]
BLAST of Cold shock domain protein vs. Ensembl Mouse
Match: Ybx3 (Y box protein 3 [Source:MGI Symbol;Acc:MGI:2137670])

HSP 1 Score: 83.1889 bits (204), Expect = 1.504e-17
Identity = 42/84 (50.00%), Postives = 53/84 (63.10%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GPDG  V G +
Sbjct:   78 VLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSR 161
[Close]
BLAST of Cold shock domain protein vs. Ensembl Mouse
Match: Ybx3 (Y box protein 3 [Source:MGI Symbol;Acc:MGI:2137670])

HSP 1 Score: 82.0333 bits (201), Expect = 1.793e-17
Identity = 42/84 (50.00%), Postives = 53/84 (63.10%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GPDG  V G +
Sbjct:   78 VLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSR 161
[Close]
BLAST of Cold shock domain protein vs. Ensembl Mouse
Match: Ybx1 (Y box protein 1 [Source:MGI Symbol;Acc:MGI:99146])

HSP 1 Score: 82.4185 bits (202), Expect = 2.222e-17
Identity = 43/87 (49.43%), Postives = 53/87 (60.92%), Query Frame = 1 
Query:   73 DYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            D  +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP G  V G K
Sbjct:   49 DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSK 135
[Close]
BLAST of Cold shock domain protein vs. Ensembl Mouse
Match: Ybx2 (Y box protein 2 [Source:MGI Symbol;Acc:MGI:1096372])

HSP 1 Score: 80.1073 bits (196), Expect = 9.821e-17
Identity = 44/85 (51.76%), Postives = 53/85 (62.35%), Query Frame = 1 
Query:   94 KVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPN 336
            +V G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP GG  V G  Y PN
Sbjct:   17 QVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEAANVTGP-GGVPVKGSRYAPN 100
[Close]
BLAST of Cold shock domain protein vs. Ensembl Mouse
Match: Ybx2 (Y box protein 2 [Source:MGI Symbol;Acc:MGI:1096372])

HSP 1 Score: 80.8777 bits (198), Expect = 1.181e-16
Identity = 45/94 (47.87%), Postives = 55/94 (58.51%), Query Frame = 1 
Query:   67 MTDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPN 336
              D  +   +V G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP GG  V G  Y PN
Sbjct:   85 QADKPVLAIQVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKRNNPRKFLRSVGDGETVEFDVVEGEKGAEAANVTGP-GGVPVKGSRYAPN 177
[Close]
BLAST of Cold shock domain protein vs. UniProt/SwissProt
Match: sp|P41824|YBOXH_APLCA (Y-box factor homolog OS=Aplysia californica OX=6500 PE=2 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 7.297e-21
Identity = 52/99 (52.53%), Postives = 62/99 (62.63%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGG 366
            I  S+V+G VKWFN KSGYGFI +D    DVFVH ++I   N      S+ DGE+V FDV+EG KG EA NV GP+G NV G K      +R   RRGG
Sbjct:   28 IIASQVSGTVKWFNVKSGYGFINRDDTKEDVFVHQTAIVKNNPRKYLRSVGDGEKVEFDVVEGEKGNEAANVTGPEGSNVQGSK---YAADRRRFRRGG 123
[Close]
BLAST of Cold shock domain protein vs. UniProt/SwissProt
Match: sp|P21573|YBOX1_XENLA (Y-box-binding protein 1 OS=Xenopus laevis OX=8355 GN=ybx1 PE=2 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 2.308e-17
Identity = 43/87 (49.43%), Postives = 54/87 (62.07%), Query Frame = 1 
Query:   73 DYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            D  +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP+G  V G K
Sbjct:   29 DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPEGVPVQGSK 115
[Close]
BLAST of Cold shock domain protein vs. UniProt/SwissProt
Match: sp|B5DE31|YBOX1_DANRE (Y-box-binding protein 1 OS=Danio rerio OX=7955 GN=ybx1 PE=1 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 7.087e-17
Identity = 43/87 (49.43%), Postives = 53/87 (60.92%), Query Frame = 1 
Query:   73 DYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            D  +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP G  V G K
Sbjct:   31 DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSK 117
[Close]
BLAST of Cold shock domain protein vs. UniProt/SwissProt
Match: sp|Q9JKB3|YBOX3_MOUSE (Y-box-binding protein 3 OS=Mus musculus OX=10090 GN=Ybx3 PE=1 SV=2)

HSP 1 Score: 83.1889 bits (204), Expect = 1.052e-16
Identity = 42/84 (50.00%), Postives = 53/84 (63.10%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GPDG  V G +
Sbjct:   78 VLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSR 161
[Close]
BLAST of Cold shock domain protein vs. UniProt/SwissProt
Match: sp|P62961|YBOX1_RAT (Y-box-binding protein 1 OS=Rattus norvegicus OX=10116 GN=Ybx1 PE=2 SV=3)

HSP 1 Score: 82.4185 bits (202), Expect = 1.554e-16
Identity = 43/87 (49.43%), Postives = 53/87 (60.92%), Query Frame = 1 
Query:   73 DYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            D  +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP G  V G K
Sbjct:   49 DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSK 135
[Close]
BLAST of Cold shock domain protein vs. TrEMBL
Match: I1ZIB0 (Y box protein-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 8.254e-39
Identity = 74/119 (62.18%), Postives = 93/119 (78.15%), Query Frame = 1 
Query:   40 LCFETILFIMTDYDIKESKVTGHVKWFNTKSGYGFIKKDVD--GADVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGGPRNDFRNQ 390
            +   +I FIMT      S+VTGHVKWF++K+GYGFI  D D    D+FVHHSSITA N+ SLADGEEVLFD+++G KGLEARNV GP+GG+V+GGKPY+P+D RSN R  G R+++RNQ
Sbjct:    9 ITINSIXFIMT-----ASQVTGHVKWFSSKNGYGFISVDDDNNSKDIFVHHSSITANNATSLADGEEVLFDIVQGAKGLEARNVTGPNGGDVIGGKPYEPSD-RSNNR--GDRDNYRNQ 119
[Close]
BLAST of Cold shock domain protein vs. TrEMBL
Match: A0A565DLG5 (Cold shock protein (Fragment) OS=Echiniscoides sigismundi OX=500494 GN=CSP PE=2 SV=1)

HSP 1 Score: 93.5893 bits (231), Expect = 4.045e-20
Identity = 49/88 (55.68%), Postives = 64/88 (72.73%), Query Frame = 1 
Query:   88 ESKVTGHVKWFNTKSGYGFIKKDV--DGADVFVHHSSITATNSNS----LADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQP 333
            E++V G VKWFN + G+GFI +D   +G D+FVHHS+I A + N+    LADGE+V FDV++G KGLEA NV GP+G NV G + YQP
Sbjct:   12 ETQVNGSVKWFNAQKGFGFIVRDGSDNGDDIFVHHSAIKAVDPNTTYRTLADGEQVTFDVVQGNKGLEAANVTGPNGNNVQGSR-YQP 98
[Close]
BLAST of Cold shock domain protein vs. TrEMBL
Match: A0A261AUY1 (CSD_1 domain-containing protein (Fragment) OS=Caenorhabditis latens OX=1503980 GN=FL83_17696 PE=4 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 4.670e-20
Identity = 48/84 (57.14%), Postives = 57/84 (67.86%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSN----SLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            +K +KV G VKWFN K+GYGFI +     D+FVH ++I   N N    SL D EEVLFD++EG KGLEA NV GPDGG V G K
Sbjct:   16 VKATKVKGTVKWFNVKNGYGFINRTDTNEDIFVHQTAIINNNPNKYLRSLGDNEEVLFDIVEGSKGLEASNVTGPDGGPVQGSK 99
[Close]
BLAST of Cold shock domain protein vs. TrEMBL
Match: G0MVG4 (CBN-CEY-1 protein OS=Caenorhabditis brenneri OX=135651 GN=Cbn-cey-1 PE=4 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 4.867e-20
Identity = 49/88 (55.68%), Postives = 59/88 (67.05%), Query Frame = 1 
Query:   70 TDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSN----SLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            T+  +K +KV G VKWFN K+GYGFI +     D+FVH ++I   N N    SL D EEVLFD++EG KGLEA NV GPDGG V G K
Sbjct:   12 TEKPVKATKVKGTVKWFNVKNGYGFINRTDTNEDIFVHQTAIINNNPNKYLRSLGDNEEVLFDIVEGSKGLEASNVTGPDGGPVQGSK 99
[Close]
BLAST of Cold shock domain protein vs. TrEMBL
Match: E3LFG7 (CRE-CEY-1 protein OS=Caenorhabditis remanei OX=31234 GN=Cre-cey-1 PE=4 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 4.930e-20
Identity = 48/84 (57.14%), Postives = 57/84 (67.86%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSN----SLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            +K +KV G VKWFN K+GYGFI +     D+FVH ++I   N N    SL D EEVLFD++EG KGLEA NV GPDGG V G K
Sbjct:   16 VKATKVKGTVKWFNVKNGYGFINRTDTNEDIFVHQTAIINNNPNKYLRSLGDNEEVLFDIVEGSKGLEASNVTGPDGGPVQGSK 99
[Close]
BLAST of Cold shock domain protein vs. Ensembl Cavefish
Match: ybx1 (Y-box binding protein 1 [Source:NCBI gene;Acc:103040011])

HSP 1 Score: 81.6481 bits (200), Expect = 2.831e-17
Identity = 43/87 (49.43%), Postives = 53/87 (60.92%), Query Frame = 1 
Query:   73 DYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            D  +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP G  V G K
Sbjct:   32 DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSK 118
[Close]
BLAST of Cold shock domain protein vs. Ensembl Cavefish
Match: YBX2 (Y-box-binding protein 2-A-like [Source:NCBI gene;Acc:103036193])

HSP 1 Score: 81.2629 bits (199), Expect = 3.495e-17
Identity = 50/113 (44.25%), Postives = 60/113 (53.10%), Query Frame = 1 
Query:   10 IKDCCLFIYILCFETILFIMTDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPN 336
            I D  L    LC       +T   I  + V G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+E  KG EA NV GP GG  V G  Y PN
Sbjct:    1 ITDRQLHSAPLCS------LTSVSIVATLVQGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKFLRSVGDGEIVEFDVVEATKGSEAANVTGP-GGVPVKGSRYAPN 106
[Close]
BLAST of Cold shock domain protein vs. Ensembl Cavefish
Match: YBX2 (Y-box-binding protein 2-A-like [Source:NCBI gene;Acc:103036193])

HSP 1 Score: 77.411 bits (189), Expect = 9.634e-16
Identity = 45/102 (44.12%), Postives = 57/102 (55.88%), Query Frame = 1 
Query:   43 CFETILFIMTDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPN 336
              ET   +  +  +  + V G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+E  KG EA NV GP GG  V G  Y PN
Sbjct:   13 AAETQEDLPPERKVIATLVQGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKFLRSVGDGEIVEFDVVEATKGSEAANVTGP-GGVPVKGSRYAPN 113
[Close]
BLAST of Cold shock domain protein vs. Ensembl Cavefish
Match: LIN28B (protein lin-28 homolog A [Source:NCBI gene;Acc:103022253])

HSP 1 Score: 63.1586 bits (152), Expect = 3.144e-11
Identity = 33/79 (41.77%), Postives = 40/79 (50.63%), Query Frame = 1 
Query:  100 TGHVKWFNTKSGYGFIKKDVDGA-------DVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVG 315
            +GH KWFN + G+GFI     G        DVFVH S +      SL +GE V F   +  KGLE   V GP G + VG
Sbjct:   38 SGHCKWFNVRMGFGFISMTSRGGNPIDPPLDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSSKGLECVRVTGPGGAHCVG 116
[Close]
BLAST of Cold shock domain protein vs. Ensembl Cavefish
Match: LIN28B (protein lin-28 homolog A [Source:NCBI gene;Acc:103022253])

HSP 1 Score: 63.1586 bits (152), Expect = 3.332e-11
Identity = 33/79 (41.77%), Postives = 40/79 (50.63%), Query Frame = 1 
Query:  100 TGHVKWFNTKSGYGFIKKDVDGA-------DVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVG 315
            +GH KWFN + G+GFI     G        DVFVH S +      SL +GE V F   +  KGLE   V GP G + VG
Sbjct:   30 SGHCKWFNVRMGFGFISMTSRGGNPIDPPLDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSSKGLECVRVTGPGGAHCVG 108
[Close]
BLAST of Cold shock domain protein vs. Ensembl Nematostella
Match: EDO41469 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S475])

HSP 1 Score: 89.7373 bits (221), Expect = 1.246e-22
Identity = 50/96 (52.08%), Postives = 61/96 (63.54%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSN----SLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIR 357
            I  +KVTG VKWFN K+GYGFI +D +  D+FVH ++I   N      S+ DGE V F+V+ G KGLEA NV GPDG  V G K Y P+  R N R
Sbjct:    3 IAATKVTGTVKWFNVKNGYGFINRDDNKEDIFVHQTAIAKNNPKKYLRSVGDGEVVEFNVVSGTKGLEASNVTGPDGEPVQGSK-YAPDRRRRNNR 97
[Close]
BLAST of Cold shock domain protein vs. Ensembl Nematostella
Match: EDO44703 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV03])

HSP 1 Score: 68.9366 bits (167), Expect = 6.466e-13
Identity = 45/117 (38.46%), Postives = 55/117 (47.01%), Query Frame = 1 
Query:   97 VTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGGPR-------------NDFRNQPYSRNS 408
             TG VKWFN   G+GFI +D  G DVFVH S+I A+   SL +GE V   +    KG  A  V  P GGNV G        +R N  + G R             +  RN PY R +
Sbjct:  483 CTGSVKWFNLIKGFGFITRDDGGEDVFVHQSAIKASGYRSLEEGEHVQLTISNSDKGKVAICVTSPGGGNVKGA-------SRKNRVKKGARKYTSLCFNCNNSGHRVRNCPYERRT 592
[Close]
BLAST of Cold shock domain protein vs. Ensembl Medaka
Match: ybx1 (Y-box binding protein 1 [Source:NCBI gene;Acc:100049221])

HSP 1 Score: 81.2629 bits (199), Expect = 3.519e-17
Identity = 43/87 (49.43%), Postives = 53/87 (60.92%), Query Frame = 1 
Query:   73 DYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGK 321
            D  +  +KV G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDV+EG KG EA NV GP G  V G K
Sbjct:   33 DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVAVQGSK 119
[Close]
BLAST of Cold shock domain protein vs. Ensembl Medaka
Match: ENSORLT00000007875.2 (Y-box binding protein 2 [Source:NCBI gene;Acc:100049372])

HSP 1 Score: 79.337 bits (194), Expect = 4.080e-16
Identity = 52/122 (42.62%), Postives = 66/122 (54.10%), Query Frame = 1 
Query:   70 TDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRG--GPRNDFRNQPYSRNSGNG 417
            ++  +  + V G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDVIE  KG EA NV GP GG  V G  Y PN  R   R    GPR   +N+P      +G
Sbjct:  103 SERKVIATAVQGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKFLRSVGDGEVVEFDVIEAAKGSEAANVTGP-GGIPVKGSRYAPNKRRFRRRFFPQGPRPADQNKPAEGQVADG 223
[Close]
BLAST of Cold shock domain protein vs. Ensembl Medaka
Match: ENSORLT00000007880.2 (Y-box binding protein 2 [Source:NCBI gene;Acc:100049372])

HSP 1 Score: 79.337 bits (194), Expect = 4.253e-16
Identity = 52/122 (42.62%), Postives = 66/122 (54.10%), Query Frame = 1 
Query:   70 TDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNS----NSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRG--GPRNDFRNQPYSRNSGNG 417
            ++  +  + V G VKWFN ++GYGFI ++    DVFVH ++I   N      S+ DGE V FDVIE  KG EA NV GP GG  V G  Y PN  R   R    GPR   +N+P      +G
Sbjct:  103 SERKVIATAVQGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKFLRSVGDGEVVEFDVIEAAKGSEAANVTGP-GGIPVKGSRYAPNKRRFRRRFFPQGPRPADQNKPAEGQVADG 223
[Close]
BLAST of Cold shock domain protein vs. Ensembl Medaka
Match: lin28b (lin-28 homolog B [Source:NCBI gene;Acc:101160951])

HSP 1 Score: 60.8474 bits (146), Expect = 2.093e-10
Identity = 33/79 (41.77%), Postives = 44/79 (55.70%), Query Frame = 1 
Query:  100 TGHVKWFNTKSGYGFIK-KDVDGA------DVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVG 315
            +G  KWFN + G+GFI   + +G+      DVFVH S +      SL +GE+V F   +  KGLE+  V GP GG  VG
Sbjct:   34 SGFCKWFNVRMGFGFISMTNSEGSPVEPPLDVFVHQSKLVMEGFRSLKEGEQVEFTYKKSSKGLESLRVTGPGGGPCVG 112
[Close]
BLAST of Cold shock domain protein vs. Ensembl Medaka
Match: lin28b (lin-28 homolog B [Source:NCBI gene;Acc:101160951])

HSP 1 Score: 60.8474 bits (146), Expect = 2.305e-10
Identity = 33/79 (41.77%), Postives = 44/79 (55.70%), Query Frame = 1 
Query:  100 TGHVKWFNTKSGYGFIK-KDVDGA------DVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVG 315
            +G  KWFN + G+GFI   + +G+      DVFVH S +      SL +GE+V F   +  KGLE+  V GP GG  VG
Sbjct:   41 SGFCKWFNVRMGFGFISMTNSEGSPVEPPLDVFVHQSKLVMEGFRSLKEGEQVEFTYKKSSKGLESLRVTGPGGGPCVG 119
[Close]
BLAST of Cold shock domain protein vs. Planmine SMEST
Match: SMESG000073546.1 (SMESG000073546.1)

HSP 1 Score: 292.352 bits (747), Expect = 1.235e-99
Identity = 203/204 (99.51%), Postives = 204/204 (100.00%), Query Frame = 1 
Query:   67 MTDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGGPRNDFRNQPYSRNSGNGGQPRRDYDRQGEIQFXXXXXXXXXXXXQVQNYNARXXXXXXXXXXXXXXXREEXXXXXXXXXXXXXXXXXXXXXXXXKAYGGGDNYE 678
            MTDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGGPRNDFRNQPYSRNSGNGGQPRRDYDRQG+IQFGRYDNDDGDRRRQVQNYNARGYGSSKSGGYQSYGQREEGSNRGGGQRYSGRGNYSGGYENRNKAYGGGDNYE
Sbjct:    1 MTDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGGPRNDFRNQPYSRNSGNGGQPRRDYDRQGDIQFGRYDNDDGDRRRQVQNYNARGYGSSKSGGYQSYGQREEGSNRGGGQRYSGRGNYSGGYENRNKAYGGGDNYE 204
[Close]
BLAST of Cold shock domain protein vs. Planmine SMEST
Match: SMESG000078868.1 (SMESG000078868.1)

HSP 1 Score: 156.762 bits (395), Expect = 2.573e-47
Identity = 87/122 (71.31%), Postives = 99/122 (81.15%), Query Frame = 1 
Query:   79 DIKESKVTGHVKWFNTKSGYGFIKK-DVDGADVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPY-QPNDNRSNIRRGGPRNDFRNQPYSRNSGNGGQPRRDY 438
            +I E+KV GHVKWFN+KSGYGFI++ D   +DVFVHHSSI ATN+NSLADGEEV FDV++G KGLEARNV GP+GG+VVGGKPY Q NDNRS   RGG   D+RNQ Y   SGNGGQ RRDY
Sbjct:    3 NIIETKVNGHVKWFNSKSGYGFIRREDRKDSDVFVHHSSIVATNANSLADGEEVQFDVVQGSKGLEARNVTGPNGGDVVGGKPYFQQNDNRSYGNRGG---DYRNQSY---SGNGGQ-RRDY 117
[Close]
BLAST of Cold shock domain protein vs. Planmine SMEST
Match: SMESG000058066.1 (SMESG000058066.1)

HSP 1 Score: 139.428 bits (350), Expect = 3.107e-40
Identity = 69/105 (65.71%), Postives = 87/105 (82.86%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVD--GADVFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGGPRNDFRNQ 390
            +  S+VTGHVKWF++K+GYGFI  D D    D+FVHHSSITA N+ SLADGEEVLFD+++G KGLEARNV GP+GG+V+GGKPY+P+D RSN R  G R+++RNQ
Sbjct:    1 MTASQVTGHVKWFSSKNGYGFISVDDDNNSKDIFVHHSSITANNATSLADGEEVLFDIVQGAKGLEARNVTGPNGGDVIGGKPYEPSD-RSNNR--GDRDNYRNQ 102
[Close]
BLAST of Cold shock domain protein vs. Planmine SMEST
Match: SMESG000058043.1 (SMESG000058043.1)

HSP 1 Score: 128.257 bits (321), Expect = 1.367e-36
Identity = 64/103 (62.14%), Postives = 81/103 (78.64%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGAD--VFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGGPRNDFR 384
            + +S+V GHVKWFN+K+GYGFI  D D +D  +FVH  SI A N+ SLADGEEVLFD++EG KGLEARNV GP+GG+VVGG PY+ N++R N  RGG R++ R
Sbjct:    1 MAQSQVVGHVKWFNSKNGYGFISVDNDNSDKDIFVHFKSIAAGNATSLADGEEVLFDIVEGAKGLEARNVTGPNGGDVVGGAPYEQNNDRFN-NRGGDRDNSR 102
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BLAST of Cold shock domain protein vs. Planmine SMEST
Match: SMESG000058039.1 (SMESG000058039.1)

HSP 1 Score: 127.487 bits (319), Expect = 3.326e-36
Identity = 72/121 (59.50%), Postives = 91/121 (75.21%), Query Frame = 1 
Query:   82 IKESKVTGHVKWFNTKSGYGFIKKDVDGAD--VFVHHSSITATNSNSLADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGGPRNDFRNQPY-SRNSGNGGQPRRD 435
            + +S+VTGHVKWFN+K+GYGFI  D +  D  VFVH  SI ATN+ SLADGEEVLFD++EG KGLEARNV GP+GG+VVGG  Y+ N++R N  RGG R++  N+ Y +R+ GN    RRD
Sbjct:    1 MAQSQVTGHVKWFNSKNGYGFISVDNERCDKDVFVHFKSIAATNATSLADGEEVLFDIVEGAKGLEARNVTGPNGGDVVGGAQYEQNNDRFN-NRGGDRDN--NRSYGNRDGGN----RRD 114
The following BLAST results are available for this feature:
BLAST of Cold shock domain protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
YBX13.786e-1749.43Y-box binding protein 1 [Source:HGNC Symbol;Acc:HG... [more]
YBX24.602e-1746.94Y-box binding protein 2 [Source:HGNC Symbol;Acc:HG... [more]
YBX24.602e-1746.94Y-box binding protein 2 [Source:HGNC Symbol;Acc:HG... [more]
YBX35.797e-1750.00Y-box binding protein 3 [Source:HGNC Symbol;Acc:HG... [more]
YBX31.182e-1650.00Y-box binding protein 3 [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of Cold shock domain protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cey-19.058e-2353.41C. Elegans Y-box [Source:UniProtKB/TrEMBL;Acc:O62... [more]
cey-46.261e-1644.32C. Elegans Y-box [Source:UniProtKB/TrEMBL;Acc:G5E... [more]
cey-46.261e-1644.32C. Elegans Y-box [Source:UniProtKB/TrEMBL;Acc:G5E... [more]
cey-21.242e-1442.50C. Elegans Y-box [Source:UniProtKB/TrEMBL;Acc:P91... [more]
cey-36.808e-1445.00C. Elegans Y-box [Source:UniProtKB/TrEMBL;Acc:P91... [more]
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BLAST of Cold shock domain protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
yps7.027e-1751.76gene:FBgn0022959 transcript:FBtr0076027[more]
yps7.997e-1751.76gene:FBgn0022959 transcript:FBtr0305992[more]
lin-285.638e-1034.19gene:FBgn0035626 transcript:FBtr0077090[more]
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BLAST of Cold shock domain protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ybx19.389e-1849.43Y box binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-... [more]
ybx19.389e-1849.43Y box binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-... [more]
ybx11.371e-1749.43Y box binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-... [more]
LIN28A2.207e-940.51si:ch1073-284b18.2 [Source:ZFIN;Acc:ZDB-GENE-11091... [more]
LIN28A2.477e-940.51si:ch1073-284b18.2 [Source:ZFIN;Acc:ZDB-GENE-11091... [more]
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BLAST of Cold shock domain protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hmgcs17.566e-1950.003-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:... [more]
hmgcs14.883e-1850.003-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:... [more]
ybx31.908e-1647.62Y-box binding protein 3 [Source:NCBI gene;Acc:5485... [more]
lin28b2.989e-937.97lin-28 homolog B [Source:NCBI gene;Acc:100216028][more]
lin28b3.222e-937.97lin-28 homolog B [Source:NCBI gene;Acc:100216028][more]
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BLAST of Cold shock domain protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ybx31.504e-1750.00Y box protein 3 [Source:MGI Symbol;Acc:MGI:2137670... [more]
Ybx31.793e-1750.00Y box protein 3 [Source:MGI Symbol;Acc:MGI:2137670... [more]
Ybx12.222e-1749.43Y box protein 1 [Source:MGI Symbol;Acc:MGI:99146][more]
Ybx29.821e-1751.76Y box protein 2 [Source:MGI Symbol;Acc:MGI:1096372... [more]
Ybx21.181e-1647.87Y box protein 2 [Source:MGI Symbol;Acc:MGI:1096372... [more]
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BLAST of Cold shock domain protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P41824|YBOXH_APLCA7.297e-2152.53Y-box factor homolog OS=Aplysia californica OX=650... [more]
sp|P21573|YBOX1_XENLA2.308e-1749.43Y-box-binding protein 1 OS=Xenopus laevis OX=8355 ... [more]
sp|B5DE31|YBOX1_DANRE7.087e-1749.43Y-box-binding protein 1 OS=Danio rerio OX=7955 GN=... [more]
sp|Q9JKB3|YBOX3_MOUSE1.052e-1650.00Y-box-binding protein 3 OS=Mus musculus OX=10090 G... [more]
sp|P62961|YBOX1_RAT1.554e-1649.43Y-box-binding protein 1 OS=Rattus norvegicus OX=10... [more]
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BLAST of Cold shock domain protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
I1ZIB08.254e-3962.18Y box protein-1 (Fragment) OS=Schmidtea mediterran... [more]
A0A565DLG54.045e-2055.68Cold shock protein (Fragment) OS=Echiniscoides sig... [more]
A0A261AUY14.670e-2057.14CSD_1 domain-containing protein (Fragment) OS=Caen... [more]
G0MVG44.867e-2055.68CBN-CEY-1 protein OS=Caenorhabditis brenneri OX=13... [more]
E3LFG74.930e-2057.14CRE-CEY-1 protein OS=Caenorhabditis remanei OX=312... [more]
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BLAST of Cold shock domain protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ybx12.831e-1749.43Y-box binding protein 1 [Source:NCBI gene;Acc:1030... [more]
YBX23.495e-1744.25Y-box-binding protein 2-A-like [Source:NCBI gene;A... [more]
YBX29.634e-1644.12Y-box-binding protein 2-A-like [Source:NCBI gene;A... [more]
LIN28B3.144e-1141.77protein lin-28 homolog A [Source:NCBI gene;Acc:103... [more]
LIN28B3.332e-1141.77protein lin-28 homolog A [Source:NCBI gene;Acc:103... [more]
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BLAST of Cold shock domain protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cold shock domain protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cold shock domain protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO414691.246e-2252.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO447036.466e-1338.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cold shock domain protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ybx13.519e-1749.43Y-box binding protein 1 [Source:NCBI gene;Acc:1000... [more]
ENSORLT00000007875.24.080e-1642.62Y-box binding protein 2 [Source:NCBI gene;Acc:1000... [more]
ENSORLT00000007880.24.253e-1642.62Y-box binding protein 2 [Source:NCBI gene;Acc:1000... [more]
lin28b2.093e-1041.77lin-28 homolog B [Source:NCBI gene;Acc:101160951][more]
lin28b2.305e-1041.77lin-28 homolog B [Source:NCBI gene;Acc:101160951][more]
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BLAST of Cold shock domain protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000073546.11.235e-9999.51SMESG000073546.1[more]
SMESG000078868.12.573e-4771.31SMESG000078868.1[more]
SMESG000058066.13.107e-4065.71SMESG000058066.1[more]
SMESG000058043.11.367e-3662.14SMESG000058043.1[more]
SMESG000058039.13.326e-3659.50SMESG000058039.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023729 ID=SMED30023729|Name=Cold shock domain protein|organism=Schmidtea mediterranea sexual|type=transcript|length=976bp
TTTTAATTGATAAAAGATTGTTGCTTGTTTATTTACATACTTTGTTTCGA
AACCATTTTATTTATCATGACTGACTATGATATTAAAGAGTCTAAGGTAA
CCGGACACGTTAAGTGGTTTAATACGAAATCTGGATATGGTTTTATCAAA
AAAGATGTTGATGGTGCTGATGTCTTTGTTCATCATTCTTCAATAACGGC
TACAAATTCAAACTCATTAGCGGATGGTGAAGAAGTTCTTTTTGATGTTA
TTGAAGGGCCCAAGGGCCTTGAGGCTAGAAATGTTTGTGGTCCCGATGGT
GGGAATGTAGTTGGTGGCAAACCTTATCAACCAAATGATAATAGGTCTAA
TATTCGTAGAGGAGGTCCTAGAAATGATTTTAGAAACCAACCATATTCAC
GTAATAGTGGTAATGGGGGACAACCTCGTAGAGATTATGATAGACAGGGA
GAAATACAATTTGGTAGATACGATAACGATGATGGGGATAGACGTCGTCA
AGTTCAAAATTATAATGCTCGTGGATATGGTAGTTCTAAAAGCGGTGGTT
ATCAGTCTTATGGACAGAGGGAAGAAGGGTCCAATAGAGGAGGTGGTCAA
CGTTATAGTGGAAGAGGAAATTATTCTGGTGGTTACGAAAATAGAAATAA
AGCATATGGGGGAGGAGATAATTATGAATAATTATCTTTGTATTGTCGGT
ATTTATTCTGAGGATATATTTCCAAGACTGCCGCGCAATTAACAAATACG
ATGTACCTGTTTTAAATAATTAAAATTTTAATGTATTTCACTGGTCATAA
TTTAAATTTTTATTTTGAAATCTTCAATGATGGTAAGCAAGGTTAAGTTT
TAAAGTTCTTACAATTTTGGAAGACGCATTCAAATCAGATATTTTGGTTC
TCGAATTCGATTAAAATTGATGGAACTTGAAATTATGTATTTTCTGTAAT
AAAAATTTCAATTTGTTTTAAAAAAA
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protein sequence of SMED30023729-orf-1

>SMED30023729-orf-1 ID=SMED30023729-orf-1|Name=SMED30023729-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=205bp
MTDYDIKESKVTGHVKWFNTKSGYGFIKKDVDGADVFVHHSSITATNSNS
LADGEEVLFDVIEGPKGLEARNVCGPDGGNVVGGKPYQPNDNRSNIRRGG
PRNDFRNQPYSRNSGNGGQPRRDYDRQGEIQFGRYDNDDGDRRRQVQNYN
ARGYGSSKSGGYQSYGQREEGSNRGGGQRYSGRGNYSGGYENRNKAYGGG
DNYE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR002059CSP_DNA-bd
IPR011129CSD
IPR012340NA-bd_OB-fold
IPR019844CSD_1
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0003676nucleic acid binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated