C-myc promoter-binding protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30023689 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of C-myc promoter-binding protein vs. Ensembl Human
Match: DENND4A (DENN domain containing 4A [Source:HGNC Symbol;Acc:HGNC:24321]) HSP 1 Score: 352.058 bits (902), Expect = 4.487e-101 Identity = 288/980 (29.39%), Postives = 446/980 (45.51%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI-----WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK-IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMD------EFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQA-RLMGKEAKYGSSY--AWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHA----DLNAFSYGLCNQIILE 2998
R+ +YF+++G ++ K + EEI D KEP+ D+ ++ + ++P + + T + ADL S V +++LC+R GRDKPP+TD+ W +KQ C +I+ T G AN+S S+S+ +YI ++RA +N + LAVTDICII+ +K E P + +VD ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W N P P F TFVLT + ++YGAA+ FYE E+ LT ++ + S+ K I+ ++ +CLLS WP F F + L F+ + + P+ +PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W Y+P L ++ +P P+++G+DSR+FD + P V C+D+ T +I P+ CK L L+N ++ ++ R +MD +F ++ I I+E FL + + + Y++YL P++ + ++ +F + FL+S DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + DM+ L++ D KSEHT + PP+ +P + NGE+ L P+ N+ L PE + A N +S + F KQ + K AK SS W+ LL Y LWF+ LP + R L+ A +L M ++ PDEVCYR+L+ L Q L V L + D NA +YG N+ +LE
Sbjct: 8 RVADYFVVAGLTDVSKPLE--------EEIHFNDA--CHKVAKPKEPITDVSVIIKSLGEEVPQDYICIDVTPTGL-SADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDWKERLKQG--CE-----IIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYE---------------SFSLPESV---PLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLYRYS-----ISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKILPKKPCKNL--------------MNTLNNLHQQLAKLQQ----RPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKV-DMDKS--GEVRLIELDESFKSEHTVFVTPPE-----------------------IPHL--------PNGEEPPLQYSYNGFPVLRNN---------------------LFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKV---------RALKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLE 857
BLAST of C-myc promoter-binding protein vs. Ensembl Human
Match: DENND4A (DENN domain containing 4A [Source:HGNC Symbol;Acc:HGNC:24321]) HSP 1 Score: 355.91 bits (912), Expect = 1.472e-98 Identity = 288/985 (29.24%), Postives = 450/985 (45.69%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI-----WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK-IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMD------EFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDE--NGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSN----IRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHA----DLNAFSYGLCNQIILE 2998
R+ +YF+++G ++ K + EEI D KEP+ D+ ++ + ++P + + T + ADL S V +++LC+R GRDKPP+TD+ W +KQ C +I+ T G AN+S S+S+ +YI ++RA +N + LAVTDICII+ +K E P + +VD ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W N P P F TFVLT + ++YGAA+ FYE E+ LT ++ + S+ K I+ ++ +CLLS WP F F + L F+ R++ + P+ +PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W Y+P L ++ +P P+++G+DSR+FD + P V C+D+ T +I P+ CK L L+N ++ ++ R +MD +F ++ I I+E FL + + + Y++YL P++ + ++ +F + FL+S DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + DM+ L++ D KSEHT + +TP I NGE+ L P+ N+ L PE + A N + + + M +R +E+K A + K +Y S W+ LL Y LWF+ LP + R L+ A +L M ++ PDEVCYR+L+ L Q L V L + D NA +YG N+ +LE
Sbjct: 8 RVADYFVVAGLTDVSKPLE--------EEIHFNDA--CHKVAKPKEPITDVSVIIKSLGEEVPQDYICIDVTPTGLS-ADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDWKERLKQG--CE-----IIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYE---------------SFSLPESV---PLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLY------RYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKILPKKPCKNL--------------MNTLNNLHQQLAKLQQ----RPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKV-DMDKS--GEVRLIELDESFKSEHT---------------------------------VFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNN---------------------LFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAK--RYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKV---------RALKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLE 857 HSP 2 Score: 83.1889 bits (204), Expect = 5.849e-15 Identity = 66/238 (27.73%), Postives = 106/238 (44.54%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQ---VVVFLFWE----FASTSNPLY---RCVTNSAAMEHMAPGIKSRINEAL--TGITNNYLSDAIEALILIRIESGENANI-MSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
TV YLSP V+ KELES+L+ EG+ A+ ++F+ H I++WNL+WY+ RL LP++L + S NKY + E V++ + W+ PLY T M H+ + N+ L + + + ++D + I + + RS+YRE+ L LG + ++ D F+ Y + +L D PPS + CRK F
Sbjct: 1677 TVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLI-------------LSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTF 1901
BLAST of C-myc promoter-binding protein vs. Ensembl Human
Match: DENND4A (DENN domain containing 4A [Source:HGNC Symbol;Acc:HGNC:24321]) HSP 1 Score: 355.91 bits (912), Expect = 1.548e-98 Identity = 288/985 (29.24%), Postives = 450/985 (45.69%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI-----WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK-IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMD------EFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDE--NGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSN----IRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHA----DLNAFSYGLCNQIILE 2998
R+ +YF+++G ++ K + EEI D KEP+ D+ ++ + ++P + + T + ADL S V +++LC+R GRDKPP+TD+ W +KQ C +I+ T G AN+S S+S+ +YI ++RA +N + LAVTDICII+ +K E P + +VD ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W N P P F TFVLT + ++YGAA+ FYE E+ LT ++ + S+ K I+ ++ +CLLS WP F F + L F+ R++ + P+ +PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W Y+P L ++ +P P+++G+DSR+FD + P V C+D+ T +I P+ CK L L+N ++ ++ R +MD +F ++ I I+E FL + + + Y++YL P++ + ++ +F + FL+S DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + DM+ L++ D KSEHT + +TP I NGE+ L P+ N+ L PE + A N + + + M +R +E+K A + K +Y S W+ LL Y LWF+ LP + R L+ A +L M ++ PDEVCYR+L+ L Q L V L + D NA +YG N+ +LE
Sbjct: 8 RVADYFVVAGLTDVSKPLE--------EEIHFNDA--CHKVAKPKEPITDVSVIIKSLGEEVPQDYICIDVTPTGLS-ADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDWKERLKQG--CE-----IIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYE---------------SFSLPESV---PLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLY------RYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKILPKKPCKNL--------------MNTLNNLHQQLAKLQQ----RPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKV-DMDKS--GEVRLIELDESFKSEHT---------------------------------VFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNN---------------------LFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAK--RYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKV---------RALKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLE 857 HSP 2 Score: 82.4185 bits (202), Expect = 9.787e-15 Identity = 66/235 (28.09%), Postives = 109/235 (46.38%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEIL------VNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEAL--TGITNNYLSDAIEALILIRIESGENANI-MSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
TV YLSP V+ KELES+L+ EG+ A+ ++F+ H I++WNL+WY+ RL LP++L L+ K + S +KY ++ + L +++ W S S L T M H+ + N+ L + + + ++D + I + + RS+YRE+ L LG + ++ D F+ Y + +L D PPS + CRK F
Sbjct: 1678 TVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHSQSRTLL-FETQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTF 1911
BLAST of C-myc promoter-binding protein vs. Ensembl Human
Match: DENND4A (DENN domain containing 4A [Source:HGNC Symbol;Acc:HGNC:24321]) HSP 1 Score: 355.525 bits (911), Expect = 1.587e-98 Identity = 288/985 (29.24%), Postives = 450/985 (45.69%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI-----WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK-IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMD------EFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDE--NGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSN----IRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHA----DLNAFSYGLCNQIILE 2998
R+ +YF+++G ++ K + EEI D KEP+ D+ ++ + ++P + + T + ADL S V +++LC+R GRDKPP+TD+ W +KQ C +I+ T G AN+S S+S+ +YI ++RA +N + LAVTDICII+ +K E P + +VD ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W N P P F TFVLT + ++YGAA+ FYE E+ LT ++ + S+ K I+ ++ +CLLS WP F F + L F+ R++ + P+ +PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W Y+P L ++ +P P+++G+DSR+FD + P V C+D+ T +I P+ CK L L+N ++ ++ R +MD +F ++ I I+E FL + + + Y++YL P++ + ++ +F + FL+S DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + DM+ L++ D KSEHT + +TP I NGE+ L P+ N+ L PE + A N + + + M +R +E+K A + K +Y S W+ LL Y LWF+ LP + R L+ A +L M ++ PDEVCYR+L+ L Q L V L + D NA +YG N+ +LE
Sbjct: 8 RVADYFVVAGLTDVSKPLE--------EEIHFNDA--CHKVAKPKEPITDVSVIIKSLGEEVPQDYICIDVTPTGLS-ADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDWKERLKQG--CE-----IIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYE---------------SFSLPESV---PLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLY------RYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKILPKKPCKNL--------------MNTLNNLHQQLAKLQQ----RPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKV-DMDKS--GEVRLIELDESFKSEHT---------------------------------VFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNN---------------------LFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAK--RYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKV---------RALKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLE 857 HSP 2 Score: 82.8037 bits (203), Expect = 6.657e-15 Identity = 66/238 (27.73%), Postives = 106/238 (44.54%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQ---VVVFLFWE----FASTSNPLY---RCVTNSAAMEHMAPGIKSRINEAL--TGITNNYLSDAIEALILIRIESGENANI-MSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
TV YLSP V+ KELES+L+ EG+ A+ ++F+ H I++WNL+WY+ RL LP++L + S NKY + E V++ + W+ PLY T M H+ + N+ L + + + ++D + I + + RS+YRE+ L LG + ++ D F+ Y + +L D PPS + CRK F
Sbjct: 1634 TVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLI-------------LSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTF 1858
BLAST of C-myc promoter-binding protein vs. Ensembl Human
Match: DENND4C (DENN domain containing 4C [Source:HGNC Symbol;Acc:HGNC:26079]) HSP 1 Score: 341.658 bits (875), Expect = 4.474e-94 Identity = 235/735 (31.97%), Postives = 365/735 (49.66%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK-IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITK----SIKPPENNCKYLDYXXXXXXXXXXXXXY-GLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQT-----KDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNM---------RDMNDETVNAASLLQTDSVIKSEHTKVLDPPDP 2311
R+ +YF+++G ++T D +EI D K T K P+ DI I+ ++ +P+G+ V+ T S YG ELFLC++ GRDKPP+TDI ++ + +I T G AN+ SS++S ++I ++RAP P ++LAVTDIC+I+ +K E P + +VD ++ G ++ +CYKKS+ N ++++ +I+ P E P D FC+P GAT+E W P P F TFVLT + ++YGAA+ FYE + L+ +++ + + K I ++ +CLLS WP F+ F + L+FI + + P+ +PIE IS F+ + FP+PQ P IL+Q HD P+ LP +G NF L+ L E L +++L E KILL S + LTG+AEA++AMIFPF+W YIP L ++ +P P+++GVDSR+FD P+ V CIDL T S + N K L Y LS+ K Q+ + + +F+ +K + I+E FLR + + + Y+ YL P++ + + D +FD GFLKS DR Y + TQ++ FI E S+ ++ D GLAFFD CI+ + ++ ++ L++ D KSEHT + PP+P
Sbjct: 8 RVTDYFVVAGLTDTSTLLD--------QEINRLDTKSTGP----KAPITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCE--VILATPYGRCANVNNSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDYE-----------------SFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTNKCICLLSHWPFFEAFRKFLMFIYKLS-----VSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPL-------SGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKT-----QEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAEDTRLIELDDSQKSEHTVFIMPPEP 694 HSP 2 Score: 85.8853 bits (211), Expect = 8.228e-16 Identity = 69/236 (29.24%), Postives = 109/236 (46.19%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLYRCVTN------SAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
+V YLSP VLRKELES+L+ EG+ + S F+ +H I++WNL+WY+ RL LP++L LT +G L +S S +K V + L W+ PLY N S+ + + + I +N + I L+ +++ G RS+YRE+ L LG + ++ + F+ Y + L + ++ D PPS +CRK F
Sbjct: 1684 SVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNEGVQLPLSSLSQDSKL-----------VYIQLLWDNINLHQEPREPLYVSWRNFNSEKKSSLLSEEQQETSTLVETIRQSIQHNNVLKPIN-LLSQQMKPGMKRQ---RSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEWCRKCF 1904 HSP 3 Score: 56.6102 bits (135), Expect = 6.380e-7 Identity = 41/133 (30.83%), Postives = 60/133 (45.11%), Query Frame = 2
Query: 2612 MLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILI----HQLRPIRLHVSELLKHADLNAFSYGLCNQIILE 2998
M KR +E+K A + K Y + WA L S Y LWF+ LP + + + R LQ A +L M + DEVCYRV++ L H + +R+ NA +YG N+++LE
Sbjct: 745 MAKRTKQEIKTAHKLAKRC-YTNPPQWAKCLFSHCYSLWFICLPAYV---------RVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTARIKPNAITYGYYNKVVLE 867 HSP 4 Score: 55.4546 bits (132), Expect = 1.349e-6 Identity = 20/43 (46.51%), Postives = 31/43 (72.09%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCN 4477
++ V M++CSQC C VYD++IM GW+ +DS+L + CP+C
Sbjct: 1484 AMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCK 1526
BLAST of C-myc promoter-binding protein vs. Ensembl Celegans
Match: denn-4 (DENN domain type RAB GEF [Source:UniProtKB/TrEMBL;Acc:U4PRB8]) HSP 1 Score: 293.123 bits (749), Expect = 7.950e-80 Identity = 257/987 (26.04%), Postives = 446/987 (45.19%), Query Frame = 2
Query: 176 SLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK----------IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDH-----DHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFR-LPEGVGCIDLITKSIK------------PPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI------MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDM--NDETVNAASLLQTDSVIKSEHTKVLDP-PDPVVTKLLNSPRKV----FPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLR--PIRLHVSELLKHADL--NAFSYGLCNQIILE 2998
S ++RR+ E+F+I+G + + L ++ EE ++ T+ P+ DI ++ + K PDGF ++++T + + ADL +G +FLC++ G +K P+ DI + + + D +++ T G A+++++S +Y+ ++RAP N+ VTDI +ILANK E+ P Y ++ ++ + +G + ICYKKS L+++P ++ P + D + L +++ A FC+P GA +E W + P SF TFVLT+ N + YG+AV FYE+ + + +E T E Y + S+CL+SR+P F +F + L F+ + ++P +PIE +IS ++ V+FPTP+ P + +Q D QLP + G ++ L E ++ L + L EQKIL+ S L +AE++ A++FPF W YIP L ++ +P P++ GVDSR+F+ + P+ V C DL T +I P+ K L L+ Y +N K+ Q L K R+R I + FL+ + + + YQ +L P+ + + +FD+DGFL+S DR+ Y+ +TQ + FI ERS+ ++ + AFFD CI + + ++ LL+ D+ HT V P P+P + + + FP ++ S+ + +++NG+D +P V+ S +A +R + + S+ L A + W+ LL SY LWF+ L L+ TA + ++IL+LA +LD M + D+VCYR+L+ L + + + V ++ A L NA +YG+ ++ +++
Sbjct: 10 SHDERRLFEHFVIAGLAENQP---LERLKPSSEE---CGLRNTQPL----APITDIAVIFPSLGEKPPDGFDVIEST-TLGYPADLNHGSIGQKSVFLCYKRGYNKLPLVDIGILDEGRGDKPMIDS-NVVQTTPFGRCASVNNASQG-IYLTYRRAPPNSSQSQFVVTDIKVILANKGEIPPHTYYKITKNLNKGLVGSDVFICYKKSQGTAKRLAYKPAVLDYFPRS-----------DHSGEMEDFKLAQNV---AMFCLPMGALIECWPTKCAPPDRSFSTFVLTDENGTKFYGSAVTFYEKYTKQLSEDQLEQLDLKSDEGGTVEDSGSNNDPADDILFYKNVSICLISRFPFFNSFKRFLFFLHRMSSTPSCSHP---VPIERYISHLMYEVSFPTPRRPRVFMQLGAENISFDSHDDSQLPLN-------GAQLIDTLKYLGSENLMYLMLLALLEQKILIHSLRPWMLAAVAESVCALMFPFHWQCPYIPQCPLGLAGVLHAPLPFIAGVDSRYFELYEDPPDDVTCFDLDTSTISFSTVRATFKTSMLPKKPAKQLKSALEDIFGKLQKQDYS-TNSKSDGGFIPVDQDLVKQ-----------RQRREFENEIHDAFLKFIASIMKGYQAFLRPIKGAPMTEHATDTGNLFDLDGFLRSRDRSSADFYKRFSETQSFMRFIEERSFVSDKNTYNAFFDDCIAKLTSAVEDGRDISGVQLLEPDT--SHSHTTVFIPAPEPFLNQETGEELQFVYGEFPSKMRSE------YFQLDRLEKNGKDGE-------------------------------KVPMHFVSEASRCSA---VRTKPETRSSL------------LAATNAVKTNPLHWSKTLLFYSYSLWFMQLDSLL-----TAAPNK----KKILRLAFNVLDRMEKTEIFPLDQVCYRILIELCGKYSEPEMAVKVMRAMQRAGLEQNAVTYGIYHRAVMD 884 HSP 2 Score: 89.7373 bits (221), Expect = 1.734e-17 Identity = 85/354 (24.01%), Postives = 148/354 (41.81%), Query Frame = 2
Query: 4352 IHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS--------NRTHSNSPSYRFTPKLNF-LVYINHPDP---QNGKINTQSLAYTNT-----------VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGE---SLSAASQSSRNKYEILV-------NLTGF----EQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALI-LIRIESGENANIMSR-SIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI 5296
+ V + T + C +C+ VYD++IM GW +D +L ++CP+C+ S N T + S F P+L + +I Q G + ++ V ++SP VLR+ELE++L + + A+ H +++WNL++Y RL LP+HL S W+ + +Q + + N F E++ L ST ++ VT+S + N L A++ L+ R+ + ++ + I+R++ V G + D + Y+S +L K + + D+P S T CRK F PL L
Sbjct: 1206 LEVILCTATYCPSCRTMVYDEEIMAGWKVDDQNLNTICPHCSGSGTATDAVSNETAAIQESV-FAPRLKIRMRWIEEMKSSWYQPGGLQETPISTPEKTTSTPSDIQLEVAFVSPLVLRRELETLLSTDKD-AMRNESLKTTHPVVFWNLIYYLRRLSLPSHLFS----WIAERHHIRCVFDLPTQHDETRLPLYFYNPNHDGNAPSFGDFTEKITRKLEDGSDSTGYATWKTVTDS--------------------VNKNLLFKAVQTLVNSSRLVKNGSVHVGAHFPIFRDIQFASIDVFGRALLRDALDTQYDSESNKLPPKIKEILPLQDHPLSHVTRACRKVFMPLDLF 1533
BLAST of C-myc promoter-binding protein vs. Ensembl Celegans
Match: denn-4 (DENN domain type RAB GEF [Source:UniProtKB/TrEMBL;Acc:U4PRB8]) HSP 1 Score: 293.123 bits (749), Expect = 7.950e-80 Identity = 257/987 (26.04%), Postives = 446/987 (45.19%), Query Frame = 2
Query: 176 SLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK----------IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDH-----DHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFR-LPEGVGCIDLITKSIK------------PPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI------MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDM--NDETVNAASLLQTDSVIKSEHTKVLDP-PDPVVTKLLNSPRKV----FPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLR--PIRLHVSELLKHADL--NAFSYGLCNQIILE 2998
S ++RR+ E+F+I+G + + L ++ EE ++ T+ P+ DI ++ + K PDGF ++++T + + ADL +G +FLC++ G +K P+ DI + + + D +++ T G A+++++S +Y+ ++RAP N+ VTDI +ILANK E+ P Y ++ ++ + +G + ICYKKS L+++P ++ P + D + L +++ A FC+P GA +E W + P SF TFVLT+ N + YG+AV FYE+ + + +E T E Y + S+CL+SR+P F +F + L F+ + ++P +PIE +IS ++ V+FPTP+ P + +Q D QLP + G ++ L E ++ L + L EQKIL+ S L +AE++ A++FPF W YIP L ++ +P P++ GVDSR+F+ + P+ V C DL T +I P+ K L L+ Y +N K+ Q L K R+R I + FL+ + + + YQ +L P+ + + +FD+DGFL+S DR+ Y+ +TQ + FI ERS+ ++ + AFFD CI + + ++ LL+ D+ HT V P P+P + + + FP ++ S+ + +++NG+D +P V+ S +A +R + + S+ L A + W+ LL SY LWF+ L L+ TA + ++IL+LA +LD M + D+VCYR+L+ L + + + V ++ A L NA +YG+ ++ +++
Sbjct: 10 SHDERRLFEHFVIAGLAENQP---LERLKPSSEE---CGLRNTQPL----APITDIAVIFPSLGEKPPDGFDVIEST-TLGYPADLNHGSIGQKSVFLCYKRGYNKLPLVDIGILDEGRGDKPMIDS-NVVQTTPFGRCASVNNASQG-IYLTYRRAPPNSSQSQFVVTDIKVILANKGEIPPHTYYKITKNLNKGLVGSDVFICYKKSQGTAKRLAYKPAVLDYFPRS-----------DHSGEMEDFKLAQNV---AMFCLPMGALIECWPTKCAPPDRSFSTFVLTDENGTKFYGSAVTFYEKYTKQLSEDQLEQLDLKSDEGGTVEDSGSNNDPADDILFYKNVSICLISRFPFFNSFKRFLFFLHRMSSTPSCSHP---VPIERYISHLMYEVSFPTPRRPRVFMQLGAENISFDSHDDSQLPLN-------GAQLIDTLKYLGSENLMYLMLLALLEQKILIHSLRPWMLAAVAESVCALMFPFHWQCPYIPQCPLGLAGVLHAPLPFIAGVDSRYFELYEDPPDDVTCFDLDTSTISFSTVRATFKTSMLPKKPAKQLKSALEDIFGKLQKQDYS-TNSKSDGGFIPVDQDLVKQ-----------RQRREFENEIHDAFLKFIASIMKGYQAFLRPIKGAPMTEHATDTGNLFDLDGFLRSRDRSSADFYKRFSETQSFMRFIEERSFVSDKNTYNAFFDDCIAKLTSAVEDGRDISGVQLLEPDT--SHSHTTVFIPAPEPFLNQETGEELQFVYGEFPSKMRSE------YFQLDRLEKNGKDGE-------------------------------KVPMHFVSEASRCSA---VRTKPETRSSL------------LAATNAVKTNPLHWSKTLLFYSYSLWFMQLDSLL-----TAAPNK----KKILRLAFNVLDRMEKTEIFPLDQVCYRILIELCGKYSEPEMAVKVMRAMQRAGLEQNAVTYGIYHRAVMD 884 HSP 2 Score: 89.7373 bits (221), Expect = 1.734e-17 Identity = 85/354 (24.01%), Postives = 148/354 (41.81%), Query Frame = 2
Query: 4352 IHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS--------NRTHSNSPSYRFTPKLNF-LVYINHPDP---QNGKINTQSLAYTNT-----------VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGE---SLSAASQSSRNKYEILV-------NLTGF----EQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALI-LIRIESGENANIMSR-SIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI 5296
+ V + T + C +C+ VYD++IM GW +D +L ++CP+C+ S N T + S F P+L + +I Q G + ++ V ++SP VLR+ELE++L + + A+ H +++WNL++Y RL LP+HL S W+ + +Q + + N F E++ L ST ++ VT+S + N L A++ L+ R+ + ++ + I+R++ V G + D + Y+S +L K + + D+P S T CRK F PL L
Sbjct: 1206 LEVILCTATYCPSCRTMVYDEEIMAGWKVDDQNLNTICPHCSGSGTATDAVSNETAAIQESV-FAPRLKIRMRWIEEMKSSWYQPGGLQETPISTPEKTTSTPSDIQLEVAFVSPLVLRRELETLLSTDKD-AMRNESLKTTHPVVFWNLIYYLRRLSLPSHLFS----WIAERHHIRCVFDLPTQHDETRLPLYFYNPNHDGNAPSFGDFTEKITRKLEDGSDSTGYATWKTVTDS--------------------VNKNLLFKAVQTLVNSSRLVKNGSVHVGAHFPIFRDIQFASIDVFGRALLRDALDTQYDSESNKLPPKIKEILPLQDHPLSHVTRACRKVFMPLDLF 1533
BLAST of C-myc promoter-binding protein vs. Ensembl Celegans
Match: denn-4 (DENN domain type RAB GEF [Source:UniProtKB/TrEMBL;Acc:U4PRB8]) HSP 1 Score: 292.738 bits (748), Expect = 8.758e-80 Identity = 262/987 (26.55%), Postives = 449/987 (45.49%), Query Frame = 2
Query: 176 SLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK----------IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDH-----DHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFR-LPEGVGCIDLITKSIK------------PPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI------MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDM--NDETVNAASLLQTDSVIKSEHTKVLDP-PDPVVTKLLNSPRKV----FPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLR--PIRLHVSELLKHADL--NAFSYGLCNQIILE 2998
S ++RR+ E+F+I+G + + L ++ EE ++ T+ P+ DI ++ + K PDGF ++++T + + ADL +G +FLC++ G +K P+ DI + + + D +++ T G A+++++S +Y+ ++RAP N+ VTDI +ILANK E+ P Y ++ ++ + +G + ICYKKS L+++P ++ P + D + L +++ A FC+P GA +E W + P SF TFVLT+ N + YG+AV FYE+ + + +E T E Y + S+CL+SR+P F +F + L F+ + ++P +PIE +IS ++ V+FPTP+ P + +Q D QLP + G ++ L E ++ L + L EQKIL+ S L +AE++ A++FPF W YIP L ++ +P P++ GVDSR+F+ + P+ V C DL T +I P+ K L L+ Y +N K+ Q L K R+R I + FL+ + + + YQ +L P+ + + +FD+DGFL+S DR+ Y+ +TQ + FI ERS+ ++ + AFFD CI + + ++ LL+ D+ HT V P P+P + + + FP ++ S+ + +++NG+D P+ H E +++ T T LL +A NA VK + L W+ LL SY LWF+ L L+ TA + ++IL+LA +LD M + D+VCYR+L+ L + + + V ++ A L NA +YG+ ++ +++
Sbjct: 10 SHDERRLFEHFVIAGLAENQP---LERLKPSSEE---CGLRNTQPL----APITDIAVIFPSLGEKPPDGFDVIEST-TLGYPADLNHGSIGQKSVFLCYKRGYNKLPLVDIGILDEGRGDKPMIDS-NVVQTTPFGRCASVNNASQG-IYLTYRRAPPNSSQSQFVVTDIKVILANKGEIPPHTYYKITKNLNKGLVGSDVFICYKKSQGTAKRLAYKPAVLDYFPRS-----------DHSGEMEDFKLAQNV---AMFCLPMGALIECWPTKCAPPDRSFSTFVLTDENGTKFYGSAVTFYEKYTKQLSEDQLEQLDLKSDEGGTVEDSGSNNDPADDILFYKNVSICLISRFPFFNSFKRFLFFLHRMSSTPSCSHP---VPIERYISHLMYEVSFPTPRRPRVFMQLGAENISFDSHDDSQLPLN-------GAQLIDTLKYLGSENLMYLMLLALLEQKILIHSLRPWMLAAVAESVCALMFPFHWQCPYIPQCPLGLAGVLHAPLPFIAGVDSRYFELYEDPPDDVTCFDLDTSTISFSTVRATFKTSMLPKKPAKQLKSALEDIFGKLQKQDYS-TNSKSDGGFIPVDQDLVKQ-----------RQRREFENEIHDAFLKFIASIMKGYQAFLRPIKGAPMTEHATDTGNLFDLDGFLRSRDRSSADFYKRFSETQSFMRFIEERSFVSDKNTYNAFFDDCIAKLTSAVEDGRDISGVQLLEPDT--SHSHTTVFIPAPEPFLNQETGEELQFVYGEFPSKMRSE------YFQLDRLEKNGKDGE------KVPM------HFEASRCSAVRTKPETRSSLL----AATNA---------VKTNPLH-----------------------WSKTLLFYSYSLWFMQLDSLL-----TAAPNK----KKILRLAFNVLDRMEKTEIFPLDQVCYRILIELCGKYSEPEMAVKVMRAMQRAGLEQNAVTYGIYHRAVMD 882 HSP 2 Score: 90.1225 bits (222), Expect = 1.690e-17 Identity = 85/354 (24.01%), Postives = 148/354 (41.81%), Query Frame = 2
Query: 4352 IHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS--------NRTHSNSPSYRFTPKLNF-LVYINHPDP---QNGKINTQSLAYTNT-----------VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGE---SLSAASQSSRNKYEILV-------NLTGF----EQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALI-LIRIESGENANIMSR-SIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI 5296
+ V + T + C +C+ VYD++IM GW +D +L ++CP+C+ S N T + S F P+L + +I Q G + ++ V ++SP VLR+ELE++L + + A+ H +++WNL++Y RL LP+HL S W+ + +Q + + N F E++ L ST ++ VT+S + N L A++ L+ R+ + ++ + I+R++ V G + D + Y+S +L K + + D+P S T CRK F PL L
Sbjct: 1204 LEVILCTATYCPSCRTMVYDEEIMAGWKVDDQNLNTICPHCSGSGTATDAVSNETAAIQESV-FAPRLKIRMRWIEEMKSSWYQPGGLQETPISTPEKTTSTPSDIQLEVAFVSPLVLRRELETLLSTDKD-AMRNESLKTTHPVVFWNLIYYLRRLSLPSHLFS----WIAERHHIRCVFDLPTQHDETRLPLYFYNPNHDGNAPSFGDFTEKITRKLEDGSDSTGYATWKTVTDS--------------------VNKNLLFKAVQTLVNSSRLVKNGSVHVGAHFPIFRDIQFASIDVFGRALLRDALDTQYDSESNKLPPKIKEILPLQDHPLSHVTRACRKVFMPLDLF 1531
BLAST of C-myc promoter-binding protein vs. Ensembl Celegans
Match: denn-4 (DENN domain type RAB GEF [Source:UniProtKB/TrEMBL;Acc:U4PRB8]) HSP 1 Score: 292.738 bits (748), Expect = 8.758e-80 Identity = 262/987 (26.55%), Postives = 449/987 (45.49%), Query Frame = 2
Query: 176 SLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK----------IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDH-----DHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFR-LPEGVGCIDLITKSIK------------PPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI------MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDM--NDETVNAASLLQTDSVIKSEHTKVLDP-PDPVVTKLLNSPRKV----FPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLR--PIRLHVSELLKHADL--NAFSYGLCNQIILE 2998
S ++RR+ E+F+I+G + + L ++ EE ++ T+ P+ DI ++ + K PDGF ++++T + + ADL +G +FLC++ G +K P+ DI + + + D +++ T G A+++++S +Y+ ++RAP N+ VTDI +ILANK E+ P Y ++ ++ + +G + ICYKKS L+++P ++ P + D + L +++ A FC+P GA +E W + P SF TFVLT+ N + YG+AV FYE+ + + +E T E Y + S+CL+SR+P F +F + L F+ + ++P +PIE +IS ++ V+FPTP+ P + +Q D QLP + G ++ L E ++ L + L EQKIL+ S L +AE++ A++FPF W YIP L ++ +P P++ GVDSR+F+ + P+ V C DL T +I P+ K L L+ Y +N K+ Q L K R+R I + FL+ + + + YQ +L P+ + + +FD+DGFL+S DR+ Y+ +TQ + FI ERS+ ++ + AFFD CI + + ++ LL+ D+ HT V P P+P + + + FP ++ S+ + +++NG+D P+ H E +++ T T LL +A NA VK + L W+ LL SY LWF+ L L+ TA + ++IL+LA +LD M + D+VCYR+L+ L + + + V ++ A L NA +YG+ ++ +++
Sbjct: 10 SHDERRLFEHFVIAGLAENQP---LERLKPSSEE---CGLRNTQPL----APITDIAVIFPSLGEKPPDGFDVIEST-TLGYPADLNHGSIGQKSVFLCYKRGYNKLPLVDIGILDEGRGDKPMIDS-NVVQTTPFGRCASVNNASQG-IYLTYRRAPPNSSQSQFVVTDIKVILANKGEIPPHTYYKITKNLNKGLVGSDVFICYKKSQGTAKRLAYKPAVLDYFPRS-----------DHSGEMEDFKLAQNV---AMFCLPMGALIECWPTKCAPPDRSFSTFVLTDENGTKFYGSAVTFYEKYTKQLSEDQLEQLDLKSDEGGTVEDSGSNNDPADDILFYKNVSICLISRFPFFNSFKRFLFFLHRMSSTPSCSHP---VPIERYISHLMYEVSFPTPRRPRVFMQLGAENISFDSHDDSQLPLN-------GAQLIDTLKYLGSENLMYLMLLALLEQKILIHSLRPWMLAAVAESVCALMFPFHWQCPYIPQCPLGLAGVLHAPLPFIAGVDSRYFELYEDPPDDVTCFDLDTSTISFSTVRATFKTSMLPKKPAKQLKSALEDIFGKLQKQDYS-TNSKSDGGFIPVDQDLVKQ-----------RQRREFENEIHDAFLKFIASIMKGYQAFLRPIKGAPMTEHATDTGNLFDLDGFLRSRDRSSADFYKRFSETQSFMRFIEERSFVSDKNTYNAFFDDCIAKLTSAVEDGRDISGVQLLEPDT--SHSHTTVFIPAPEPFLNQETGEELQFVYGEFPSKMRSE------YFQLDRLEKNGKDGE------KVPM------HFEASRCSAVRTKPETRSSLL----AATNA---------VKTNPLH-----------------------WSKTLLFYSYSLWFMQLDSLL-----TAAPNK----KKILRLAFNVLDRMEKTEIFPLDQVCYRILIELCGKYSEPEMAVKVMRAMQRAGLEQNAVTYGIYHRAVMD 882 HSP 2 Score: 90.1225 bits (222), Expect = 1.690e-17 Identity = 85/354 (24.01%), Postives = 148/354 (41.81%), Query Frame = 2
Query: 4352 IHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS--------NRTHSNSPSYRFTPKLNF-LVYINHPDP---QNGKINTQSLAYTNT-----------VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGE---SLSAASQSSRNKYEILV-------NLTGF----EQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALI-LIRIESGENANIMSR-SIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI 5296
+ V + T + C +C+ VYD++IM GW +D +L ++CP+C+ S N T + S F P+L + +I Q G + ++ V ++SP VLR+ELE++L + + A+ H +++WNL++Y RL LP+HL S W+ + +Q + + N F E++ L ST ++ VT+S + N L A++ L+ R+ + ++ + I+R++ V G + D + Y+S +L K + + D+P S T CRK F PL L
Sbjct: 1204 LEVILCTATYCPSCRTMVYDEEIMAGWKVDDQNLNTICPHCSGSGTATDAVSNETAAIQESV-FAPRLKIRMRWIEEMKSSWYQPGGLQETPISTPEKTTSTPSDIQLEVAFVSPLVLRRELETLLSTDKD-AMRNESLKTTHPVVFWNLIYYLRRLSLPSHLFS----WIAERHHIRCVFDLPTQHDETRLPLYFYNPNHDGNAPSFGDFTEKITRKLEDGSDSTGYATWKTVTDS--------------------VNKNLLFKAVQTLVNSSRLVKNGSVHVGAHFPIFRDIQFASIDVFGRALLRDALDTQYDSESNKLPPKIKEILPLQDHPLSHVTRACRKVFMPLDLF 1531
BLAST of C-myc promoter-binding protein vs. Ensembl Celegans
Match: denn-4 (DENN domain type RAB GEF [Source:UniProtKB/TrEMBL;Acc:U4PRB8]) HSP 1 Score: 292.352 bits (747), Expect = 1.185e-79 Identity = 262/989 (26.49%), Postives = 449/989 (45.40%), Query Frame = 2
Query: 176 SLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK------------IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDH-----DHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFR-LPEGVGCIDLITKSIK------------PPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI------MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDM--NDETVNAASLLQTDSVIKSEHTKVLDP-PDPVVTKLLNSPRKV----FPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLR--PIRLHVSELLKHADL--NAFSYGLCNQIILE 2998
S ++RR+ E+F+I+G + + L ++ EE ++ T+ P+ DI ++ + K PDGF ++++T + + ADL +G +FLC++ G +K P+ DI + + + D +++ T G A+++++S +Y+ ++RAP N+ VTDI +ILANK E+ P Y ++ ++ + +G + ICYKKS L+++P ++ P + D + L +++ A FC+P GA +E W + P SF TFVLT+ N + YG+AV FYE+ + + +E T E Y + S+CL+SR+P F +F + L F+ + ++P +PIE +IS ++ V+FPTP+ P + +Q D QLP + G ++ L E ++ L + L EQKIL+ S L +AE++ A++FPF W YIP L ++ +P P++ GVDSR+F+ + P+ V C DL T +I P+ K L L+ Y +N K+ Q L K R+R I + FL+ + + + YQ +L P+ + + +FD+DGFL+S DR+ Y+ +TQ + FI ERS+ ++ + AFFD CI + + ++ LL+ D+ HT V P P+P + + + FP ++ S+ + +++NG+D P+ H E +++ T T LL +A NA VK + L W+ LL SY LWF+ L L+ TA + ++IL+LA +LD M + D+VCYR+L+ L + + + V ++ A L NA +YG+ ++ +++
Sbjct: 10 SHDERRLFEHFVIAGLAENQP---LERLKPSSEE---CGLRNTQPL----APITDIAVIFPSLGEKPPDGFDVIEST-TLGYPADLNHGSIGQKSVFLCYKRGYNKLPLVDIGILDEGRGDKPMIDS-NVVQTTPFGRCASVNNASQG-IYLTYRRAPPNSSQSQFVVTDIKVILANKGEIPPHTYYKITKNLNKGLVGSDVFICYKKSQGTAKRLAYKPAVLDYFPRS-----------DHSGEMEDFKLAQNV---AMFCLPMGALIECWPTKCAPPDRSFSTFVLTDENGTKFYGSAVTFYEKYTKQLSEDQLEQLDLKSDEGGTVEDSGSNNDPADDLQILFYKNVSICLISRFPFFNSFKRFLFFLHRMSSTPSCSHP---VPIERYISHLMYEVSFPTPRRPRVFMQLGAENISFDSHDDSQLPLN-------GAQLIDTLKYLGSENLMYLMLLALLEQKILIHSLRPWMLAAVAESVCALMFPFHWQCPYIPQCPLGLAGVLHAPLPFIAGVDSRYFELYEDPPDDVTCFDLDTSTISFSTVRATFKTSMLPKKPAKQLKSALEDIFGKLQKQDYS-TNSKSDGGFIPVDQDLVKQ-----------RQRREFENEIHDAFLKFIASIMKGYQAFLRPIKGAPMTEHATDTGNLFDLDGFLRSRDRSSADFYKRFSETQSFMRFIEERSFVSDKNTYNAFFDDCIAKLTSAVEDGRDISGVQLLEPDT--SHSHTTVFIPAPEPFLNQETGEELQFVYGEFPSKMRSE------YFQLDRLEKNGKDGE------KVPM------HFEASRCSAVRTKPETRSSLL----AATNA---------VKTNPLH-----------------------WSKTLLFYSYSLWFMQLDSLL-----TAAPNK----KKILRLAFNVLDRMEKTEIFPLDQVCYRILIELCGKYSEPEMAVKVMRAMQRAGLEQNAVTYGIYHRAVMD 884 HSP 2 Score: 89.7373 bits (221), Expect = 1.778e-17 Identity = 85/354 (24.01%), Postives = 148/354 (41.81%), Query Frame = 2
Query: 4352 IHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS--------NRTHSNSPSYRFTPKLNF-LVYINHPDP---QNGKINTQSLAYTNT-----------VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGE---SLSAASQSSRNKYEILV-------NLTGF----EQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALI-LIRIESGENANIMSR-SIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI 5296
+ V + T + C +C+ VYD++IM GW +D +L ++CP+C+ S N T + S F P+L + +I Q G + ++ V ++SP VLR+ELE++L + + A+ H +++WNL++Y RL LP+HL S W+ + +Q + + N F E++ L ST ++ VT+S + N L A++ L+ R+ + ++ + I+R++ V G + D + Y+S +L K + + D+P S T CRK F PL L
Sbjct: 1206 LEVILCTATYCPSCRTMVYDEEIMAGWKVDDQNLNTICPHCSGSGTATDAVSNETAAIQESV-FAPRLKIRMRWIEEMKSSWYQPGGLQETPISTPEKTTSTPSDIQLEVAFVSPLVLRRELETLLSTDKD-AMRNESLKTTHPVVFWNLIYYLRRLSLPSHLFS----WIAERHHIRCVFDLPTQHDETRLPLYFYNPNHDGNAPSFGDFTEKITRKLEDGSDSTGYATWKTVTDS--------------------VNKNLLFKAVQTLVNSSRLVKNGSVHVGAHFPIFRDIQFASIDVFGRALLRDALDTQYDSESNKLPPKIKEILPLQDHPLSHVTRACRKVFMPLDLF 1533
BLAST of C-myc promoter-binding protein vs. Ensembl Fly
Match: Crag (gene:FBgn0025864 transcript:FBtr0071219) HSP 1 Score: 306.22 bits (783), Expect = 1.292e-83 Identity = 268/976 (27.46%), Postives = 468/976 (47.95%), Query Frame = 2
Query: 179 LNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAAS-FCMPWGATLESW-----SLNRSIPKPSFLTFVLTNVNYN-RMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQW--DHDHPIGIQLPTDA-LSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGES-IRECFLRAVILMFRNYQNYLIPVSFSQT-----KDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNI--RNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLP-DEVCYRVLLIL--IHQLRPIRLHVSELLKHADL--NAFSYGLCNQIILEQEQQWSQKLSNLS 3037
+ ++RI +YF+++G + L + + + A I EP+ DI + ++P+G+ I+ +T + +G + ++ FR G+D+PP+ DI + + + ++ +T G AN+++SS+ ++ ++RA + P + L VT++C+I+ +K E P A+ + ++ + +G + +CYKKSM + +S++PEI+ P P ++C + FC+P GA+LE+W + R P F TFVLT + ++YG+A+ FYE+ DE +L+ E+ E + ++ +++CLLS P TF++ L ++ + + IP+E +I+Q L V FP AP+I LQ + + I + P D+ L R G G F+ L++ L + + + + LTEQKIL+ S + LT +AEA+++++FPFKW YIP L ++ +P PYLIGVDSRFFD + P V CIDL T +I E+ ++L + ++ + + E + + ++ N +D RKRE + E I+E FL + + R Y+++L+P+S + + +F + FL+S D++ + ++ + TQ++ FI ERS+ ++ D GL+FFD C + + + DET L+ D+ SE TK + PPD V +P P L N E+ L P + S K +LS FL + ++++ S I R + +K+S K A + + S Y A + Y L+FL LP ++ + G IL+ A +L + +RL + DE CYR+++ L IH L + + + L+K + + NA +YG N+ +L E QW Q + +S
Sbjct: 1 MEEKRIADYFVVAGMPENPQL--LQENSFNDSGRLRAATTI--------EPITDIGVYFPLLGEEVPEGYEILSHTPTGLQANLNHGSVRTTDCYIYFRRGKDRPPLVDIGVLYDGHERIMSDAE--IVAETPGGRVANVNNSSAK-TFLTYRRARADMPCNELVVTELCVIVQSKGERAPHAFCLIYKTLNKGYVGSDVYLCYKKSMYRPKHISYKPEILLRYPTFD-----------------HTDFPLNLCPSVPLFCLPMGASLEAWPHVNGTEKRKPISPVFSTFVLTVSDGTYKVYGSALTFYEDYDESKLSAEQKELLGWDEEFGAQ--HSLHMIKAICLLSHHPFGDTFDKWLKYL----HRMVLYDVNIPIPVERYITQLLDEVPFP---APSIHLQLSSESNDRILLTQPEDSPLPRSGAG--FHILLQNLGTDNCLHVLLLALTEQKILIHSLRPATLTAVAEAIVSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPTDVTCIDLDTNNISLCESQ-RHLSPKLLPKRAARL--------LRQTLTELENAKPISYDSTNSLDRDIRKRKRELVLEQRIQEAFLLFMASILRGYRDFLVPISKAPSVGATDPSALFQLKAFLRSRDKSHQKFFELMMKTQMFIRFIEERSFVSDGDHGLSFFDECAEKVGNY-DETPAQLHLVDWDTGQNSERTKYIFPPDSV------TPAGSQPGGGGGGLAY------------NYENFTLQ------PELLQSTKKT------ALSK------FLQLQLNASLSPGSPIARRTKHEIKLSQ--------KMASRCQQHPEAWSKYLLA-----TCYSLYFLILPSMV------LDPRHAGKEPEILRAAYDVL--VRASRLKITCDEFCYRIMMQLCGIHNLPVLAVRLHYLMKRSGVQANALTYGFYNRCVL--ESQWPQDSTTIS 866 HSP 2 Score: 154.836 bits (390), Expect = 3.693e-37 Identity = 117/360 (32.50%), Postives = 178/360 (49.44%), Query Frame = 2
Query: 4244 SLGAIRLPTGKYWPDSQIDGDSPAAAAAPCIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDP-QNGK---INTQSLAYTNTVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEIL-VNLTGFEQVV---VFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRE-LFCLITAVLGNQVNYDVFNFTYNSPWQQL-KRKYQAYVKTHDNPPSEQTLFCRKFFRPLQL 5293
S GA+ + PD+ S AA C + + +TTCSQC NC VYD++IM+GW+ DS+L + C CN + R + DP Q+GK N S + TV YL+P VLRKELE++L QEG+IAL+K EF+ EH I+YWNLLW R+ THL L + + E + S+ + L NL+ + ++L + ++PL + + A + K+ I + ++ I N + ++ L R + N S S YR+ LF +TA+ + V+ F+ Y + + +L +R+ Y + D PPS T+FCR +FRPL L
Sbjct: 1328 STGALHMHAFPAVPDNLYSLTSENAADRDC-----DVLIQLTTCSQCHNCSVLVYDEEIMSGWTAEDSNLNTTCHACNKLTVPFLSVQIERQVEE------SEQSDPLQDGKEQIANGNSHKTSLTVPYLNPLVLRKELENILTQEGDIALIKPEFVDEHPIIYWNLLWLMERIESKTHLPE-LCLPVPSDKEHIDPLSKVKTVHIQCLWDNLSLHTEASGPPMYLLYRETQPTSPLIKALLTDQAQLN-----KNVIQQIISAIRCNDFATPLKRLANERHKLKSNGVERSHSFYRDILFLALTAIGRSNVDLATFHREYAAVFDKLTERECNMYYRNQDLPPSASTIFCRAYFRPLLL 1670
BLAST of C-myc promoter-binding protein vs. Ensembl Fly
Match: Crag (gene:FBgn0025864 transcript:FBtr0343356) HSP 1 Score: 306.22 bits (783), Expect = 1.292e-83 Identity = 268/976 (27.46%), Postives = 468/976 (47.95%), Query Frame = 2
Query: 179 LNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAAS-FCMPWGATLESW-----SLNRSIPKPSFLTFVLTNVNYN-RMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQW--DHDHPIGIQLPTDA-LSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGES-IRECFLRAVILMFRNYQNYLIPVSFSQT-----KDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNI--RNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLP-DEVCYRVLLIL--IHQLRPIRLHVSELLKHADL--NAFSYGLCNQIILEQEQQWSQKLSNLS 3037
+ ++RI +YF+++G + L + + + A I EP+ DI + ++P+G+ I+ +T + +G + ++ FR G+D+PP+ DI + + + ++ +T G AN+++SS+ ++ ++RA + P + L VT++C+I+ +K E P A+ + ++ + +G + +CYKKSM + +S++PEI+ P P ++C + FC+P GA+LE+W + R P F TFVLT + ++YG+A+ FYE+ DE +L+ E+ E + ++ +++CLLS P TF++ L ++ + + IP+E +I+Q L V FP AP+I LQ + + I + P D+ L R G G F+ L++ L + + + + LTEQKIL+ S + LT +AEA+++++FPFKW YIP L ++ +P PYLIGVDSRFFD + P V CIDL T +I E+ ++L + ++ + + E + + ++ N +D RKRE + E I+E FL + + R Y+++L+P+S + + +F + FL+S D++ + ++ + TQ++ FI ERS+ ++ D GL+FFD C + + + DET L+ D+ SE TK + PPD V +P P L N E+ L P + S K +LS FL + ++++ S I R + +K+S K A + + S Y A + Y L+FL LP ++ + G IL+ A +L + +RL + DE CYR+++ L IH L + + + L+K + + NA +YG N+ +L E QW Q + +S
Sbjct: 1 MEEKRIADYFVVAGMPENPQL--LQENSFNDSGRLRAATTI--------EPITDIGVYFPLLGEEVPEGYEILSHTPTGLQANLNHGSVRTTDCYIYFRRGKDRPPLVDIGVLYDGHERIMSDAE--IVAETPGGRVANVNNSSAK-TFLTYRRARADMPCNELVVTELCVIVQSKGERAPHAFCLIYKTLNKGYVGSDVYLCYKKSMYRPKHISYKPEILLRYPTFD-----------------HTDFPLNLCPSVPLFCLPMGASLEAWPHVNGTEKRKPISPVFSTFVLTVSDGTYKVYGSALTFYEDYDESKLSAEQKELLGWDEEFGAQ--HSLHMIKAICLLSHHPFGDTFDKWLKYL----HRMVLYDVNIPIPVERYITQLLDEVPFP---APSIHLQLSSESNDRILLTQPEDSPLPRSGAG--FHILLQNLGTDNCLHVLLLALTEQKILIHSLRPATLTAVAEAIVSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPTDVTCIDLDTNNISLCESQ-RHLSPKLLPKRAARL--------LRQTLTELENAKPISYDSTNSLDRDIRKRKRELVLEQRIQEAFLLFMASILRGYRDFLVPISKAPSVGATDPSALFQLKAFLRSRDKSHQKFFELMMKTQMFIRFIEERSFVSDGDHGLSFFDECAEKVGNY-DETPAQLHLVDWDTGQNSERTKYIFPPDSV------TPAGSQPGGGGGGLAY------------NYENFTLQ------PELLQSTKKT------ALSK------FLQLQLNASLSPGSPIARRTKHEIKLSQ--------KMASRCQQHPEAWSKYLLA-----TCYSLYFLILPSMV------LDPRHAGKEPEILRAAYDVL--VRASRLKITCDEFCYRIMMQLCGIHNLPVLAVRLHYLMKRSGVQANALTYGFYNRCVL--ESQWPQDSTTIS 866 HSP 2 Score: 154.836 bits (390), Expect = 3.693e-37 Identity = 117/360 (32.50%), Postives = 178/360 (49.44%), Query Frame = 2
Query: 4244 SLGAIRLPTGKYWPDSQIDGDSPAAAAAPCIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDP-QNGK---INTQSLAYTNTVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEIL-VNLTGFEQVV---VFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRE-LFCLITAVLGNQVNYDVFNFTYNSPWQQL-KRKYQAYVKTHDNPPSEQTLFCRKFFRPLQL 5293
S GA+ + PD+ S AA C + + +TTCSQC NC VYD++IM+GW+ DS+L + C CN + R + DP Q+GK N S + TV YL+P VLRKELE++L QEG+IAL+K EF+ EH I+YWNLLW R+ THL L + + E + S+ + L NL+ + ++L + ++PL + + A + K+ I + ++ I N + ++ L R + N S S YR+ LF +TA+ + V+ F+ Y + + +L +R+ Y + D PPS T+FCR +FRPL L
Sbjct: 1328 STGALHMHAFPAVPDNLYSLTSENAADRDC-----DVLIQLTTCSQCHNCSVLVYDEEIMSGWTAEDSNLNTTCHACNKLTVPFLSVQIERQVEE------SEQSDPLQDGKEQIANGNSHKTSLTVPYLNPLVLRKELENILTQEGDIALIKPEFVDEHPIIYWNLLWLMERIESKTHLPE-LCLPVPSDKEHIDPLSKVKTVHIQCLWDNLSLHTEASGPPMYLLYRETQPTSPLIKALLTDQAQLN-----KNVIQQIISAIRCNDFATPLKRLANERHKLKSNGVERSHSFYRDILFLALTAIGRSNVDLATFHREYAAVFDKLTERECNMYYRNQDLPPSASTIFCRAYFRPLLL 1670
BLAST of C-myc promoter-binding protein vs. Ensembl Fly
Match: Crag (gene:FBgn0025864 transcript:FBtr0071220) HSP 1 Score: 305.834 bits (782), Expect = 1.336e-83 Identity = 268/976 (27.46%), Postives = 468/976 (47.95%), Query Frame = 2
Query: 179 LNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAAS-FCMPWGATLESW-----SLNRSIPKPSFLTFVLTNVNYN-RMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQW--DHDHPIGIQLPTDA-LSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGES-IRECFLRAVILMFRNYQNYLIPVSFSQT-----KDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNI--RNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLP-DEVCYRVLLIL--IHQLRPIRLHVSELLKHADL--NAFSYGLCNQIILEQEQQWSQKLSNLS 3037
+ ++RI +YF+++G + L + + + A I EP+ DI + ++P+G+ I+ +T + +G + ++ FR G+D+PP+ DI + + + ++ +T G AN+++SS+ ++ ++RA + P + L VT++C+I+ +K E P A+ + ++ + +G + +CYKKSM + +S++PEI+ P P ++C + FC+P GA+LE+W + R P F TFVLT + ++YG+A+ FYE+ DE +L+ E+ E + ++ +++CLLS P TF++ L ++ + + IP+E +I+Q L V FP AP+I LQ + + I + P D+ L R G G F+ L++ L + + + + LTEQKIL+ S + LT +AEA+++++FPFKW YIP L ++ +P PYLIGVDSRFFD + P V CIDL T +I E+ ++L + ++ + + E + + ++ N +D RKRE + E I+E FL + + R Y+++L+P+S + + +F + FL+S D++ + ++ + TQ++ FI ERS+ ++ D GL+FFD C + + + DET L+ D+ SE TK + PPD V +P P L N E+ L P + S K +LS FL + ++++ S I R + +K+S K A + + S Y A + Y L+FL LP ++ + G IL+ A +L + +RL + DE CYR+++ L IH L + + + L+K + + NA +YG N+ +L E QW Q + +S
Sbjct: 1 MEEKRIADYFVVAGMPENPQL--LQENSFNDSGRLRAATTI--------EPITDIGVYFPLLGEEVPEGYEILSHTPTGLQANLNHGSVRTTDCYIYFRRGKDRPPLVDIGVLYDGHERIMSDAE--IVAETPGGRVANVNNSSAK-TFLTYRRARADMPCNELVVTELCVIVQSKGERAPHAFCLIYKTLNKGYVGSDVYLCYKKSMYRPKHISYKPEILLRYPTFD-----------------HTDFPLNLCPSVPLFCLPMGASLEAWPHVNGTEKRKPISPVFSTFVLTVSDGTYKVYGSALTFYEDYDESKLSAEQKELLGWDEEFGAQ--HSLHMIKAICLLSHHPFGDTFDKWLKYL----HRMVLYDVNIPIPVERYITQLLDEVPFP---APSIHLQLSSESNDRILLTQPEDSPLPRSGAG--FHILLQNLGTDNCLHVLLLALTEQKILIHSLRPATLTAVAEAIVSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPTDVTCIDLDTNNISLCESQ-RHLSPKLLPKRAARL--------LRQTLTELENAKPISYDSTNSLDRDIRKRKRELVLEQRIQEAFLLFMASILRGYRDFLVPISKAPSVGATDPSALFQLKAFLRSRDKSHQKFFELMMKTQMFIRFIEERSFVSDGDHGLSFFDECAEKVGNY-DETPAQLHLVDWDTGQNSERTKYIFPPDSV------TPAGSQPGGGGGGLAY------------NYENFTLQ------PELLQSTKKT------ALSK------FLQLQLNASLSPGSPIARRTKHEIKLSQ--------KMASRCQQHPEAWSKYLLA-----TCYSLYFLILPSMV------LDPRHAGKEPEILRAAYDVL--VRASRLKITCDEFCYRIMMQLCGIHNLPVLAVRLHYLMKRSGVQANALTYGFYNRCVL--ESQWPQDSTTIS 866 HSP 2 Score: 155.221 bits (391), Expect = 2.929e-37 Identity = 117/360 (32.50%), Postives = 178/360 (49.44%), Query Frame = 2
Query: 4244 SLGAIRLPTGKYWPDSQIDGDSPAAAAAPCIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDP-QNGK---INTQSLAYTNTVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEIL-VNLTGFEQVV---VFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRE-LFCLITAVLGNQVNYDVFNFTYNSPWQQL-KRKYQAYVKTHDNPPSEQTLFCRKFFRPLQL 5293
S GA+ + PD+ S AA C + + +TTCSQC NC VYD++IM+GW+ DS+L + C CN + R + DP Q+GK N S + TV YL+P VLRKELE++L QEG+IAL+K EF+ EH I+YWNLLW R+ THL L + + E + S+ + L NL+ + ++L + ++PL + + A + K+ I + ++ I N + ++ L R + N S S YR+ LF +TA+ + V+ F+ Y + + +L +R+ Y + D PPS T+FCR +FRPL L
Sbjct: 1301 STGALHMHAFPAVPDNLYSLTSENAADRDC-----DVLIQLTTCSQCHNCSVLVYDEEIMSGWTAEDSNLNTTCHACNKLTVPFLSVQIERQVEE------SEQSDPLQDGKEQIANGNSHKTSLTVPYLNPLVLRKELENILTQEGDIALIKPEFVDEHPIIYWNLLWLMERIESKTHLPE-LCLPVPSDKEHIDPLSKVKTVHIQCLWDNLSLHTEASGPPMYLLYRETQPTSPLIKALLTDQAQLN-----KNVIQQIISAIRCNDFATPLKRLANERHKLKSNGVERSHSFYRDILFLALTAIGRSNVDLATFHREYAAVFDKLTERECNMYYRNQDLPPSASTIFCRAYFRPLLL 1643
BLAST of C-myc promoter-binding protein vs. Ensembl Fly
Match: Sbf (gene:FBgn0025802 transcript:FBtr0082530) HSP 1 Score: 84.7297 bits (208), Expect = 9.454e-16 Identity = 72/267 (26.97%), Postives = 120/267 (44.94%), Query Frame = 2
Query: 953 FCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXX------------XXAYFRSKNE-TQTSEPYKI------YCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIP--IETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLP-TDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDS 1687
FC P G WSL+ +P F VLT+++ N+ Y A + F+E + + + A S + T TS P I Y + L L+SR +TF L I +T ++ +ET I L + P P + +Q P + +L G+G +F L + L ++ ++ L ++TE KIL S C LT AL+A+++PF+++ VYIP L ++ +P+P+++G+ S
Sbjct: 54 FCQPLG-----WSLSYEKQEPKFFVSVLTDIDANKHYCACLSFHETVAITQTRSVDDEDETIGSSRLLGATPSSMDGITTTSTPASITHHSVMYAPKCLVLISRLDCAETFKNCLGTI--------YTVYIENLAYGLETLIGNILGCIQVPPAGGPQVRFSIGAGDKQSLQPPQSSSLPTTGSGVHF--LFKQLGIKNVLILLCSVMTENKILFLSKCYWHLTDSCRALVALMYPFRYTHVYIPILPAPLTEVLSTPTPFIMGIHS 305
BLAST of C-myc promoter-binding protein vs. Ensembl Fly
Match: Sbf (gene:FBgn0025802 transcript:FBtr0082529) HSP 1 Score: 84.7297 bits (208), Expect = 9.882e-16 Identity = 72/267 (26.97%), Postives = 120/267 (44.94%), Query Frame = 2
Query: 953 FCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXX------------XXAYFRSKNE-TQTSEPYKI------YCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIP--IETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLP-TDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDS 1687
FC P G WSL+ +P F VLT+++ N+ Y A + F+E + + + A S + T TS P I Y + L L+SR +TF L I +T ++ +ET I L + P P + +Q P + +L G+G +F L + L ++ ++ L ++TE KIL S C LT AL+A+++PF+++ VYIP L ++ +P+P+++G+ S
Sbjct: 54 FCQPLG-----WSLSYEKQEPKFFVSVLTDIDANKHYCACLSFHETVAITQTRSVDDEDETIGSSRLLGATPSSMDGITTTSTPASITHHSVMYAPKCLVLISRLDCAETFKNCLGTI--------YTVYIENLAYGLETLIGNILGCIQVPPAGGPQVRFSIGAGDKQSLQPPQSSSLPTTGSGVHF--LFKQLGIKNVLILLCSVMTENKILFLSKCYWHLTDSCRALVALMYPFRYTHVYIPILPAPLTEVLSTPTPFIMGIHS 305
BLAST of C-myc promoter-binding protein vs. Ensembl Zebrafish
Match: dennd4c (DENN/MADD domain containing 4C [Source:ZFIN;Acc:ZDB-GENE-120727-13]) HSP 1 Score: 375.17 bits (962), Expect = 1.026e-104 Identity = 284/968 (29.34%), Postives = 462/968 (47.73%), Query Frame = 2
Query: 191 RICEYFLISGFSN--TRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXY-GLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTK-----DIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNM----------RDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLIL--IHQLRPIRLHVSELLKHADL--NAFSYGLCNQIILE 2998
R+ +YF+++G ++ T D+S+ G K P+ D+ ++N +S +P+GF +++TYS Q +G ELFLC++ GR KPP+ DI + K Q +IE T G AN+ SS++S ++I ++RAP P ++LAVTDIC+I+ NK E P + +VD ++ G ++ +CYKKS+ N ++++ +I+ P E L E + FC+P GA +E W+ N P P F TFVLTN N ++YGA + FYE D L+ ++ S + + + ++ +CLLSRWP F+ F + L+F+ + N + +PIE IS F+H V+FP+PQ P IL+Q HD P+ LP +G ++ L+ L E L ++L E KILL S + LTG+AEA++AMIFPF+W YIP L ++ +P P+++GVDSR+FD + P V C+DL T +I + ++ ++ + K + + G + + V + L + +FT +K+ + I+E FLR + + + Y+ YL P++ + ++ D ++D+ GFLKS DR + Y + TQ++ F+ E ++ ++ D GLAFFD CI+ + + E+ L++ D KSEHT + PP+P + E+G D P P S K+ P P L S A S++ + ++ + KR +E+K A + K Y + WA L S Y LWF+ LP A ++ R +Q A +L M + + + DEVCYRV++ L + ++ + + V +K A + NA +YG N+ +LE
Sbjct: 8 RVTDYFVVAGLTDKSTPLEQDISEAKSSGP----------------KAPITDLAVINKSSGETVPEGFTCIESTYSGQPANLNHGSLKSPELFLCYKRGRGKPPLIDIGVL-YEGKERLIQG-CEVIEATPFGRCANVNNSSATSQRIFITYRRAPPVQPQNSLAVTDICVIITNKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVSSSNSIAYKAGLIFRYPEEDYE---------------SFPLSESV---PLFCLPMGAKIECWAPNTRYPLPVFSTFVLTNSNGEKVYGAGIQFYEPYPVDGLSEKQKIQLGLVSAVDKKVLPNRTVNTNKCICLLSRWPFFEAFRKFLMFLYKLS-----ANGVSPLPIEKHISHFMHNVSFPSPQRPRILVQLSAHDTLILSQPVCTPLPL-------SGADYSTLLMNLGPENCATLLHFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLNAPCPFIVGVDSRYFDLYDPPPDVVCVDLDTNTIYLSDEK-RHSNWKNLPKKPSKSLISFLGSLHHQLATVRRTATEGLAVEMTPIEADFTWHKKKTELEMEIQEVFLRFMASILKGYRTYLKPITQAPSEKATAADSLYDLQGFLKSRDRAHQKFYSQLTKTQIFIRFVEECTFVSDKDTGLAFFDDCIRKLFPSDKGTDKGTKVEGESSEDTRLMELDESQKSEHTVFVMPPEPPL--------------------------------EDGPD----------PPPKYSYKNFPSLRLELFDRPLELRPAL-----STRAAGSSVSSSPAL---LAKRTKQEIKMAYKLAKRF-YSNPPQWAKCLCSHCYSLWFICLP---------ARMRTAQSKPRAMQQAFNVLLKMRSSEVEVLDEVCYRVVMQLCGLWEMPVMAVRVLMEMKKAGVEPNAITYGYYNKAVLE 866 HSP 2 Score: 92.4337 bits (228), Expect = 5.763e-18 Identity = 74/237 (31.22%), Postives = 106/237 (44.73%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLYRC-------VTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
+V YLSP VLRKELES+L+ EG+ + +FL +H I++WNL+WY+ RL LP+ L LT G L S S +K QV V L W+ + PLY+ A +H +S +N + I N + I +LIR RS+YRE+ L LG + ++ + FN Y + QL + + D PPS +C F
Sbjct: 1716 SVPYLSPLVLRKELESLLENEGDQVIYTHKFLSQHPIIFWNLVWYFRRLDLPSILPGLILTSEHCNNGVKLPQTSLSQDSK-----------QVYVQLLWDNVNLHQEPTEPLYQLWRTFLQRKGTLAPTDHQE--TRSLLNSIVRSIQMNDVYGPIN--MLIREIKKHPEVKRQRSVYREIMFLSLVALGRENIDIEAFNREYRLAYSQLSAEQLKVLSPIDRPPSNGVQWCLNSF 1937 HSP 3 Score: 56.9954 bits (136), Expect = 2.833e-7 Identity = 20/43 (46.51%), Postives = 32/43 (74.42%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCN 4477
++ V M++CSQC +C+ VYD++IM GW+ +DS+L CP+C
Sbjct: 1517 ALEVLMSSCSQCRSCEALVYDEEIMAGWTADDSNLNCTCPFCQ 1559
BLAST of C-myc promoter-binding protein vs. Ensembl Zebrafish
Match: dennd4a (DENN/MADD domain containing 4A [Source:ZFIN;Acc:ZDB-GENE-060503-285]) HSP 1 Score: 371.703 bits (953), Expect = 3.588e-104 Identity = 292/977 (29.89%), Postives = 458/977 (46.88%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGES-------IRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILE 2998
R+ +YF+++G + + K EE V+ + K P+ D+ +V + ++P G+ V+ T S A+L G S + ++FLC+R GRDKPP+TD+ + + K K C +I+ T +G AN+S SSS +YI ++RA +N LAVTDIC+I+ K E P A+ +VD ++ S G ++ +CYKKS+ K N L+F+ ++ P + LPE + FC+P GA++E WS + P F TFVLT + ++YGAA+ FYE E+ LT ++ + N + ++ ++S+CLLS WP F F L F+ R++ + P+++PIE IS F+H V FP+ Q P IL+Q HD P+ LP +G L+ L + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++GVDSR+FD + P + C+DL T +I P CK+L LSN ++ E Q+ R+ M+ F R+ + G+S I+E FLR + + + Y++YL+P++ + ++ +FD+ GFLKS DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + E L++ D +SEHT + PP+ LP++ GE+ + + + P + + EH L P +T ++P S ++ +R +E+K A+ M K Y S W+ LL + LWF+ LP + R L A +L M +L PDEVCYRVL+ L Q L V L +K A + NA +YG N+ +LE
Sbjct: 7 RVADYFVVAGLTVSSKPL---------EEDVHPEDGAHRSSAQLKAPITDVAVVIRSLGEEVPRGYTCVECTPSGLP-AELNGGSLMGPQIFLCYRRGRDKPPLTDLGILYEWKEKLKPDCQ-----IIQTTPSGRPANISGSSSQRIYITYRRAAENHSHATLAVTDICVIIPGKGETPPHAFCKVDKNLNSSMWGSSVYLCYKKSLAKTNTLAFKAGLLSRYPEEDYD---------------SFPLPESV---PLFCLPMGASIECWSSHTKYSLPVFSTFVLTGASGEKVYGAAIQFYEPYPEEHLTEKQRSQLGLQANGIRPDGSMTVHTNKSICLLSHWPFFDAFRNFLTFLY------RYSISGPHTLPIEKHISHFMHKVPFPSSQRPRILVQLSPHDSLMLSQPVSSPLPL-------SGGRLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGVDSRYFDLYEPPTDISCVDLDTNTITHKEERRSLTWKILPRKACKHL--------------INTLSNLHQQLD--EGYQMSREE--GQMEAFMSEREPGSGGKSLETLELEIQEAFLRFMAAILKGYRSYLLPITQAPSEKATDASSLFDLQGFLKSRDRSHQKFYSLMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDSDKPEDTR---LIELDKSHRSEHTVFISPPE-----------------------LPAL--------PEGEEPPM--VYSYSGFPALNAQLCEHQD--GLRVPKATSALRHISPISP--------------AAIFRRSQQEIKSAQRMAK--TYSSIPQMWSKCLLRHCHGLWFICLPAYVSACHSKV---------RALHTAYDVLRNMQDKKLQPPDEVCYRVLMQLCGQYGQPVLAVRVLFEMKKAGVQPNAITYGYYNRAVLE 856 HSP 2 Score: 118.627 bits (296), Expect = 5.362e-26 Identity = 98/338 (28.99%), Postives = 157/338 (46.45%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS-----NRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTN---------TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKG-------ESLSAASQSSRNK-YEILVNLTGFEQVVV---FLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEAL-TGITNNYLSDAIEALILIRIESGENANI-MSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
++ V M++CS+C C+ VYD++IM GW+ +DS+L S CP+C N +N +P + + + K+ S +N TV YLSP VL KELES+L+ EG+ A+ + + H I++WNL+W++ RL LP+ S ++L K S AS+ S+N +IL + Q + +L W+ S L V++S + A + E L T + N +D + + LI G RS+YR++ L LG + +N D F+ Y + + +L D PPS + CR+ F
Sbjct: 1344 AVEVRMSSCSRCNTCESLVYDEEIMAGWTADDSNLNSTCPFCGSPFLPLLNVDITNMGEQERSPCQDTSSGQTEREDEPPKVYDASSTLSNKDKKDPETVTVPYLSPLVLWKELESLLENEGDQAISSAAIVDHHPIVFWNLVWFFRRLDLPS---SLPGLYLTSKNYCRDTPQSQQSCASEDSKNVLVQILWDNCRLHQDHIQPCYLLWK----SYCLSTAVSSSLNEDEQAVSL-----ELLQTLVKNIQKNDVYQPMSLILQLLGSRLGFSRQRSLYRDILFLSLVALGKSSINIDAFDREYKTAYDRLTPSQVKMTHNCDRPPSAGVMECRRTF 1669
BLAST of C-myc promoter-binding protein vs. Ensembl Zebrafish
Match: dennd4a (DENN/MADD domain containing 4A [Source:ZFIN;Acc:ZDB-GENE-060503-285]) HSP 1 Score: 371.318 bits (952), Expect = 5.224e-104 Identity = 292/977 (29.89%), Postives = 458/977 (46.88%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGES-------IRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILE 2998
R+ +YF+++G + + K EE V+ + K P+ D+ +V + ++P G+ V+ T S A+L G S + ++FLC+R GRDKPP+TD+ + + K K C +I+ T +G AN+S SSS +YI ++RA +N LAVTDIC+I+ K E P A+ +VD ++ S G ++ +CYKKS+ K N L+F+ ++ P + LPE + FC+P GA++E WS + P F TFVLT + ++YGAA+ FYE E+ LT ++ + N + ++ ++S+CLLS WP F F L F+ R++ + P+++PIE IS F+H V FP+ Q P IL+Q HD P+ LP +G L+ L + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++GVDSR+FD + P + C+DL T +I P CK+L LSN ++ E Q+ R+ M+ F R+ + G+S I+E FLR + + + Y++YL+P++ + ++ +FD+ GFLKS DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + E L++ D +SEHT + PP+ LP++ GE+ + + + P + + EH L P +T ++P S ++ +R +E+K A+ M K Y S W+ LL + LWF+ LP + R L A +L M +L PDEVCYRVL+ L Q L V L +K A + NA +YG N+ +LE
Sbjct: 7 RVADYFVVAGLTVSSKPL---------EEDVHPEDGAHRSSAQLKAPITDVAVVIRSLGEEVPRGYTCVECTPSGLP-AELNGGSLMGPQIFLCYRRGRDKPPLTDLGILYEWKEKLKPDCQ-----IIQTTPSGRPANISGSSSQRIYITYRRAAENHSHATLAVTDICVIIPGKGETPPHAFCKVDKNLNSSMWGSSVYLCYKKSLAKTNTLAFKAGLLSRYPEEDYD---------------SFPLPESV---PLFCLPMGASIECWSSHTKYSLPVFSTFVLTGASGEKVYGAAIQFYEPYPEEHLTEKQRSQLGLQANGLRPDGSMTVHTNKSICLLSHWPFFDAFRNFLTFLY------RYSISGPHTLPIEKHISHFMHKVPFPSSQRPRILVQLSPHDSLMLSQPVSSPLPL-------SGGRLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGVDSRYFDLYEPPTDISCVDLDTNTITHKEERRSLTWKILPRKACKHL--------------INTLSNLHQQLD--EGYQMSREE--GQMEAFMSEREPGSGGKSLETLELEIQEAFLRFMAAILKGYRSYLLPITQAPSEKATDASSLFDLQGFLKSRDRSHQKFYSLMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDSDKPEDTR---LIELDKSHRSEHTVFISPPE-----------------------LPAL--------PEGEEPPM--VYSYSGFPALNAQLCEHQD--GLRVPKATSALRHISPISP--------------AAIFRRSQQEIKSAQRMAK--TYSSIPQMWSKCLLRHCHGLWFICLPAYVSACHSKV---------RALHTAYDVLRNMQDKKLQPPDEVCYRVLMQLCGQYGQPVLAVRVLFEMKKAGVQPNAITYGYYNRAVLE 856 HSP 2 Score: 121.324 bits (303), Expect = 8.190e-27 Identity = 98/334 (29.34%), Postives = 158/334 (47.31%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS-----NRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTN---------TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLS-FLTI--WLKRKGESLSAASQSSRNK-YEILVNLTGFEQVVV---FLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEAL-TGITNNYLSDAIEALILIRIESGENANI-MSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
++ V M++CS+C C+ VYD++IM GW+ +DS+L S CP+C N +N +P + + + K+ S +N TV YLSP VL KELES+L+ EG+ A+ + + H I++WNL+W++ RL LP+ L +LT + + S AS+ S+N +IL + Q + +L W+ S L V++S + A + E L T + N +D + + LI G RS+YR++ L LG + +N D F+ Y + + +L D PPS + CR+ F
Sbjct: 1385 AVEVRMSSCSRCNTCESLVYDEEIMAGWTADDSNLNSTCPFCGSPFLPLLNVDITNMGEQERSPCQDTSSSQTEREDEPSKVYDASSTLSNKDKKDPEAVTVPYLSPLVLWKELESLLENEGDQAISSAAIVDHHPIVFWNLVWFFRRLDLPSSLPGLYLTSKNYCRDTPSQQSCASEDSKNVLVQILWDNPRLHQDHIQPCYLLWK----SYCLSTAVSSSLNEDEQAVSL-----ELLQTLVKNIQKNDVYQPMSLILQLLGSRLGFSRQRSLYRDILFLSLVALGKSSINIDAFDREYKTAYDRLTPSQVKMTHNCDRPPSAGVMECRRTF 1709
BLAST of C-myc promoter-binding protein vs. Ensembl Zebrafish
Match: dennd4a (DENN/MADD domain containing 4A [Source:ZFIN;Acc:ZDB-GENE-060503-285]) HSP 1 Score: 371.318 bits (952), Expect = 5.509e-104 Identity = 292/977 (29.89%), Postives = 458/977 (46.88%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGES-------IRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILE 2998
R+ +YF+++G + + K EE V+ + K P+ D+ +V + ++P G+ V+ T S A+L G S + ++FLC+R GRDKPP+TD+ + + K K C +I+ T +G AN+S SSS +YI ++RA +N LAVTDIC+I+ K E P A+ +VD ++ S G ++ +CYKKS+ K N L+F+ ++ P + LPE + FC+P GA++E WS + P F TFVLT + ++YGAA+ FYE E+ LT ++ + N + ++ ++S+CLLS WP F F L F+ R++ + P+++PIE IS F+H V FP+ Q P IL+Q HD P+ LP +G L+ L + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++GVDSR+FD + P + C+DL T +I P CK+L LSN ++ E Q+ R+ M+ F R+ + G+S I+E FLR + + + Y++YL+P++ + ++ +FD+ GFLKS DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + E L++ D +SEHT + PP+ LP++ GE+ + + + P + + EH L P +T ++P S ++ +R +E+K A+ M K Y S W+ LL + LWF+ LP + R L A +L M +L PDEVCYRVL+ L Q L V L +K A + NA +YG N+ +LE
Sbjct: 7 RVADYFVVAGLTVSSKPL---------EEDVHPEDGAHRSSAQLKAPITDVAVVIRSLGEEVPRGYTCVECTPSGL-PAELNGGSLMGPQIFLCYRRGRDKPPLTDLGILYEWKEKLKPDCQ-----IIQTTPSGRPANISGSSSQRIYITYRRAAENHSHATLAVTDICVIIPGKGETPPHAFCKVDKNLNSSMWGSSVYLCYKKSLAKTNTLAFKAGLLSRYPEEDYD---------------SFPLPESV---PLFCLPMGASIECWSSHTKYSLPVFSTFVLTGASGEKVYGAAIQFYEPYPEEHLTEKQRSQLGLQANGIRPDGSMTVHTNKSICLLSHWPFFDAFRNFLTFLY------RYSISGPHTLPIEKHISHFMHKVPFPSSQRPRILVQLSPHDSLMLSQPVSSPLPL-------SGGRLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGVDSRYFDLYEPPTDISCVDLDTNTITHKEERRSLTWKILPRKACKHL--------------INTLSNLHQQLD--EGYQMSREE--GQMEAFMSEREPGSGGKSLETLELEIQEAFLRFMAAILKGYRSYLLPITQAPSEKATDASSLFDLQGFLKSRDRSHQKFYSLMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDSDKPEDTR---LIELDKSHRSEHTVFISPPE-----------------------LPAL--------PEGEEPPM--VYSYSGFPALNAQLCEHQD--GLRVPKATSALRHISPISP--------------AAIFRRSQQEIKSAQRMAK--TYSSIPQMWSKCLLRHCHGLWFICLPAYVSACHSKV---------RALHTAYDVLRNMQDKKLQPPDEVCYRVLMQLCGQYGQPVLAVRVLFEMKKAGVQPNAITYGYYNRAVLE 856 HSP 2 Score: 119.783 bits (299), Expect = 2.558e-26 Identity = 98/334 (29.34%), Postives = 158/334 (47.31%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS-----NRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTN---------TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLS-FLTI--WLKRKGESLSAASQSSRNK-YEILVNLTGFEQVVV---FLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEAL-TGITNNYLSDAIEALILIRIESGENANI-MSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
++ V M++CS+C C+ VYD++IM GW+ +DS+L S CP+C N +N +P + + + K+ S +N TV YLSP VL KELES+L+ EG+ A+ + + H I++WNL+W++ RL LP+ L +LT + + S AS+ S+N +IL + Q + +L W+ S L V++S + A + E L T + N +D + + LI G RS+YR++ L LG + +N D F+ Y + + +L D PPS + CR+ F
Sbjct: 1385 AVEVRMSSCSRCNTCESLVYDEEIMAGWTADDSNLNSTCPFCGSPFLPLLNVDITNMGEQERSPCQDTSSGQTEREDEPPKVYDASSTLSNKDKKDPETVTVPYLSPLVLWKELESLLENEGDQAISSAAIVDHHPIVFWNLVWFFRRLDLPSSLPGLYLTSKNYCRDTPSQQSCASEDSKNVLVQILWDNCRLHQDHIQPCYLLWK----SYCLSTAVSSSLNEDEQAVSL-----ELLQTLVKNIQKNDVYQPMSLILQLLGSRLGFSRQRSLYRDILFLSLVALGKSSINIDAFDREYKTAYDRLTPSQVKMTHNCDRPPSAGVMECRRTF 1709
BLAST of C-myc promoter-binding protein vs. Ensembl Zebrafish
Match: dennd4a (DENN/MADD domain containing 4A [Source:ZFIN;Acc:ZDB-GENE-060503-285]) HSP 1 Score: 371.318 bits (952), Expect = 5.689e-104 Identity = 292/977 (29.89%), Postives = 458/977 (46.88%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGES-------IRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILE 2998
R+ +YF+++G + + K EE V+ + K P+ D+ +V + ++P G+ V+ T S A+L G S + ++FLC+R GRDKPP+TD+ + + K K C +I+ T +G AN+S SSS +YI ++RA +N LAVTDIC+I+ K E P A+ +VD ++ S G ++ +CYKKS+ K N L+F+ ++ P + LPE + FC+P GA++E WS + P F TFVLT + ++YGAA+ FYE E+ LT ++ + N + ++ ++S+CLLS WP F F L F+ R++ + P+++PIE IS F+H V FP+ Q P IL+Q HD P+ LP +G L+ L + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++GVDSR+FD + P + C+DL T +I P CK+L LSN ++ E Q+ R+ M+ F R+ + G+S I+E FLR + + + Y++YL+P++ + ++ +FD+ GFLKS DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + E L++ D +SEHT + PP+ LP++ GE+ + + + P + + EH L P +T ++P S ++ +R +E+K A+ M K Y S W+ LL + LWF+ LP + R L A +L M +L PDEVCYRVL+ L Q L V L +K A + NA +YG N+ +LE
Sbjct: 7 RVADYFVVAGLTVSSKPL---------EEDVHPEDGAHRSSAQLKAPITDVAVVIRSLGEEVPRGYTCVECTPSGL-PAELNGGSLMGPQIFLCYRRGRDKPPLTDLGILYEWKEKLKPDCQ-----IIQTTPSGRPANISGSSSQRIYITYRRAAENHSHATLAVTDICVIIPGKGETPPHAFCKVDKNLNSSMWGSSVYLCYKKSLAKTNTLAFKAGLLSRYPEEDYD---------------SFPLPESV---PLFCLPMGASIECWSSHTKYSLPVFSTFVLTGASGEKVYGAAIQFYEPYPEEHLTEKQRSQLGLQANGIRPDGSMTVHTNKSICLLSHWPFFDAFRNFLTFLY------RYSISGPHTLPIEKHISHFMHKVPFPSSQRPRILVQLSPHDSLMLSQPVSSPLPL-------SGGRLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGVDSRYFDLYEPPTDISCVDLDTNTITHKEERRSLTWKILPRKACKHL--------------INTLSNLHQQLD--EGYQMSREE--GQMEAFMSEREPGSGGKSLETLELEIQEAFLRFMAAILKGYRSYLLPITQAPSEKATDASSLFDLQGFLKSRDRSHQKFYSLMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDSDKPEDTR---LIELDKSHRSEHTVFISPPE-----------------------LPAL--------PEGEEPPM--VYSYSGFPALNAQLCEHQD--GLRVPKATSALRHISPISP--------------AAIFRRSQQEIKSAQRMAK--TYSSIPQMWSKCLLRHCHGLWFICLPAYVSACHSKV---------RALHTAYDVLRNMQDKKLQPPDEVCYRVLMQLCGQYGQPVLAVRVLFEMKKAGVQPNAITYGYYNRAVLE 856 HSP 2 Score: 117.857 bits (294), Expect = 1.073e-25 Identity = 98/338 (28.99%), Postives = 157/338 (46.45%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS-----NRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTN---------TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKG-------ESLSAASQSSRNK-YEILVNLTGFEQVVV---FLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEAL-TGITNNYLSDAIEALILIRIESGENANI-MSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
++ V M++CS+C C+ VYD++IM GW+ +DS+L S CP+C N +N +P + + + K+ S +N TV YLSP VL KELES+L+ EG+ A+ + + H I++WNL+W++ RL LP+ S ++L K S AS+ S+N +IL + Q + +L W+ S L V++S + A + E L T + N +D + + LI G RS+YR++ L LG + +N D F+ Y + + +L D PPS + CR+ F
Sbjct: 1385 AVEVRMSSCSRCNTCESLVYDEEIMAGWTADDSNLNSTCPFCGSPFLPLLNVDITNMGEQERSPCQDTSSGQTEREDEPPKVYDASSTLSNKDKKDPETVTVPYLSPLVLWKELESLLENEGDQAISSAAIVDHHPIVFWNLVWFFRRLDLPS---SLPGLYLTSKNYCRDTPQSQQSCASEDSKNVLVQILWDNCRLHQDHIQPCYLLWK----SYCLSTAVSSSLNEDEQAVSL-----ELLQTLVKNIQKNDVYQPMSLILQLLGSRLGFSRQRSLYRDILFLSLVALGKSSINIDAFDREYKTAYDRLTPSQVKMTHNCDRPPSAGVMECRRTF 1710
BLAST of C-myc promoter-binding protein vs. Ensembl Xenopus
Match: DENND4A (DENN domain containing 4A [Source:NCBI gene;Acc:100490151]) HSP 1 Score: 366.696 bits (940), Expect = 3.951e-102 Identity = 288/976 (29.51%), Postives = 460/976 (47.13%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLY-GKSAVDELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFE---KQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMR-DMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADL----NAFSYGLCNQIILE 2998
R+ +YF+++G +++ K + EEI D KEP+ D+ ++ + ++P G+ + T + ADL G +++LC+R GRDKPP+TD+ + + + K C +I+ T G AN+S S+S+ ++I ++RA ++ ++LAVTDICII+ +K E P + +V+ ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W + + P P F TFVLT + ++YGAA+ FYE +D+LT ++ + S E Q I+ ++ +CLLS WP F F + L F+ R++ + P+ +PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W YIP L ++ +P P+++G+DSR+FD + P V C+DL T +I P+ CK L L N ++ + +++ + N D F ++ + I+E FL + + + Y++YL P++ + ++ +F++ GFLKS DR+ Y + TQ++ FI E S+ ++ D LAFFD C++ D ET L++ D +SEHT + PP+ P LP+ P N NG + DL + TP + H + ++TP S P M +R +E++ A + K+ Y S W+ LL Y LWF+ LP + R L+ A +L M++ ++ PDEVCYRVL+ L Q L V L + + NA +YG N+ +LE
Sbjct: 8 RVADYFVVTGLTDSSKPLE--------EEIHFNDA--CHKTAKPKEPITDVTVIIKSLGEEVPQGYVCIDLTPTGLS-ADLNNGSIRGPQIYLCYRRGRDKPPLTDLGVLYEWKERLKQGCK-----IIQATPYGRPANISGSASSQRVFITYRRAAESMTQNSLAVTDICIIIPSKGETPPHTFCKVEKNLNSSVWGSAVYLCYKKSVAKTNAVSYKAGLICRYPEEDYE---------------SFPLPESV---PLFCLPMGATIECWPSDSNYPLPVFSTFVLTGASAEKVYGAAIQFYEPYAQDQLTEKQQVHLGLLSSAEGQMDSSKSIHVNKCICLLSHWPFFDAFKKFLTFLY------RYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDTLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQIEGKRNVTWKILPKKACKNL--------------LNTLCNLYQQLAELQHRPREEAFMELAMNDYD-FNYGKRMHQLDMEIQEAFLCFMASILKGYRSYLRPITQAPSETATDASSLFELQGFLKSRDRSHHKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVEKADVDRPGET----RLIELDESHRSEHTVFITPPE-------------IPH-------LPNGEEPPKNYSYNGFPVLILDL-FDTPDGLMK----SHKLSTKVTTPCSPSP-------------------------MFRRTKQEIRSAHKIAKQ--YSSIPQMWSRCLLRHCYGLWFICLPAYVKFCHSKV---------RALRTAYDVLRKMHMKKIDSPDEVCYRVLMQLCGQYGQPVLAVKVLFEMRKVGVQPNAITYGYYNKAVLE 856 HSP 2 Score: 87.8113 bits (216), Expect = 1.811e-16 Identity = 68/233 (29.18%), Postives = 108/233 (46.35%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLY---RCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
TV YLSP V+ KELES+L+ EG+ ++ S F+ H I++WNL+WY+ RL LP++L L+ K +S + S+ +K+ V++ + W+ PLY + + GI I NN + L I+ G RS+YRE+ L LG + ++ DVF+ Y + +++L + + D PPS + CRK F
Sbjct: 1623 TVPYLSPLVVWKELESLLENEGDQSITVSGFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEQCNKNSKVSRSCMSADSKH-----------VLIQVLWDNLKLHQDPRQPLYILWNTIKEELFDQQFLRGIVRSIK------NNNVYGPVSQILDCIKQVPGRTRQ---RSLYREILFLSLVALGRENIDIDVFDREYKTAYERLTPEQLNCTQICDRPPSIGVMECRKTF 1835
BLAST of C-myc promoter-binding protein vs. Ensembl Xenopus
Match: DENND4A (DENN domain containing 4A [Source:NCBI gene;Acc:100490151]) HSP 1 Score: 366.696 bits (940), Expect = 5.288e-102 Identity = 288/976 (29.51%), Postives = 460/976 (47.13%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLY-GKSAVDELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFE---KQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMR-DMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADL----NAFSYGLCNQIILE 2998
R+ +YF+++G +++ K + EEI D KEP+ D+ ++ + ++P G+ + T + ADL G +++LC+R GRDKPP+TD+ + + + K C +I+ T G AN+S S+S+ ++I ++RA ++ ++LAVTDICII+ +K E P + +V+ ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W + + P P F TFVLT + ++YGAA+ FYE +D+LT ++ + S E Q I+ ++ +CLLS WP F F + L F+ R++ + P+ +PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W YIP L ++ +P P+++G+DSR+FD + P V C+DL T +I P+ CK L L N ++ + +++ + N D F ++ + I+E FL + + + Y++YL P++ + ++ +F++ GFLKS DR+ Y + TQ++ FI E S+ ++ D LAFFD C++ D ET L++ D +SEHT + PP+ P LP+ P N NG + DL + TP + H + ++TP S P M +R +E++ A + K+ Y S W+ LL Y LWF+ LP + R L+ A +L M++ ++ PDEVCYRVL+ L Q L V L + + NA +YG N+ +LE
Sbjct: 8 RVADYFVVTGLTDSSKPLE--------EEIHFNDA--CHKTAKPKEPITDVTVIIKSLGEEVPQGYVCIDLTPTGL-SADLNNGSIRGPQIYLCYRRGRDKPPLTDLGVLYEWKERLKQGCK-----IIQATPYGRPANISGSASSQRVFITYRRAAESMTQNSLAVTDICIIIPSKGETPPHTFCKVEKNLNSSVWGSAVYLCYKKSVAKTNAVSYKAGLICRYPEEDYE---------------SFPLPESV---PLFCLPMGATIECWPSDSNYPLPVFSTFVLTGASAEKVYGAAIQFYEPYAQDQLTEKQQVHLGLLSSAEGQMDSSKSIHVNKCICLLSHWPFFDAFKKFLTFLY------RYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDTLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQIEGKRNVTWKILPKKACKNL--------------LNTLCNLYQQLAELQHRPREEAFMELAMNDYD-FNYGKRMHQLDMEIQEAFLCFMASILKGYRSYLRPITQAPSETATDASSLFELQGFLKSRDRSHHKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVEKADVDRPGET----RLIELDESHRSEHTVFITPPE-------------IPH-------LPNGEEPPKNYSYNGFPVLILDL-FDTPDGLMK----SHKLSTKVTTPCSPSP-------------------------MFRRTKQEIRSAHKIAKQ--YSSIPQMWSRCLLRHCYGLWFICLPAYVKFCHSKV---------RALRTAYDVLRKMHMKKIDSPDEVCYRVLMQLCGQYGQPVLAVKVLFEMRKVGVQPNAITYGYYNKAVLE 856 HSP 2 Score: 88.9669 bits (219), Expect = 8.185e-17 Identity = 72/241 (29.88%), Postives = 116/241 (48.13%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEIL------VNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMA-PGIKSR---INEALTGIT-----NNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
TV YLSP V+ KELES+L+ EG+ ++ S F+ H I++WNL+WY+ RL LP++L L+ K +S + S+ +K+ ++ + L + +++ W S + R V +A P IK + L GI NN + L I+ G RS+YRE+ L LG + ++ DVF+ Y + +++L + + D PPS + CRK F
Sbjct: 1645 TVPYLSPLVVWKELESLLENEGDQSITVSGFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEQCNKNSKVSRSCMSADSKHVLIQVLWDNLKLHQDPRQPLYILWNTISQN----RTVLFDTQEHALAVPQIKEEELFDQQFLRGIVRSIKNNNVYGPVSQILDCIKQVPGRTRQ---RSLYREILFLSLVALGRENIDIDVFDREYKTAYERLTPEQLNCTQICDRPPSIGVMECRKTF 1878
BLAST of C-myc promoter-binding protein vs. Ensembl Xenopus
Match: DENND4A (DENN domain containing 4A [Source:NCBI gene;Acc:100490151]) HSP 1 Score: 365.155 bits (936), Expect = 1.639e-101 Identity = 288/976 (29.51%), Postives = 460/976 (47.13%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLY-GKSAVDELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFE---KQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMR-DMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADL----NAFSYGLCNQIILE 2998
R+ +YF+++G +++ K + EEI D KEP+ D+ ++ + ++P G+ + T + ADL G +++LC+R GRDKPP+TD+ + + + K C +I+ T G AN+S S+S+ ++I ++RA ++ ++LAVTDICII+ +K E P + +V+ ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W + + P P F TFVLT + ++YGAA+ FYE +D+LT ++ + S E Q I+ ++ +CLLS WP F F + L F+ R++ + P+ +PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W YIP L ++ +P P+++G+DSR+FD + P V C+DL T +I P+ CK L L N ++ + +++ + N D F ++ + I+E FL + + + Y++YL P++ + ++ +F++ GFLKS DR+ Y + TQ++ FI E S+ ++ D LAFFD C++ D ET L++ D +SEHT + PP+ P LP+ P N NG + DL + TP + H + ++TP S P M +R +E++ A + K+ Y S W+ LL Y LWF+ LP + R L+ A +L M++ ++ PDEVCYRVL+ L Q L V L + + NA +YG N+ +LE
Sbjct: 8 RVADYFVVTGLTDSSKPLE--------EEIHFNDA--CHKTAKPKEPITDVTVIIKSLGEEVPQGYVCIDLTPTGL-SADLNNGSIRGPQIYLCYRRGRDKPPLTDLGVLYEWKERLKQGCK-----IIQATPYGRPANISGSASSQRVFITYRRAAESMTQNSLAVTDICIIIPSKGETPPHTFCKVEKNLNSSVWGSAVYLCYKKSVAKTNAVSYKAGLICRYPEEDYE---------------SFPLPESV---PLFCLPMGATIECWPSDSNYPLPVFSTFVLTGASAEKVYGAAIQFYEPYAQDQLTEKQQVHLGLLSSAEGQMDSSKSIHVNKCICLLSHWPFFDAFKKFLTFLY------RYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDTLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQIEGKRNVTWKILPKKACKNL--------------LNTLCNLYQQLAELQHRPREEAFMELAMNDYD-FNYGKRMHQLDMEIQEAFLCFMASILKGYRSYLRPITQAPSETATDASSLFELQGFLKSRDRSHHKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVEKADVDRPGET----RLIELDESHRSEHTVFITPPE-------------IPH-------LPNGEEPPKNYSYNGFPVLILDL-FDTPDGLMK----SHKLSTKVTTPCSPSP-------------------------MFRRTKQEIRSAHKIAKQ--YSSIPQMWSRCLLRHCYGLWFICLPAYVKFCHSKV---------RALRTAYDVLRKMHMKKIDSPDEVCYRVLMQLCGQYGQPVLAVKVLFEMRKVGVQPNAITYGYYNKAVLE 856 HSP 2 Score: 94.7449 bits (234), Expect = 1.371e-18 Identity = 74/240 (30.83%), Postives = 115/240 (47.92%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLYRCVTNSAAMEH--MAPGIKSR---INEALTGIT-----NNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
TV YLSP V+ KELES+L+ EG+ ++ S F+ H I++WNL+WY+ RL LP++L L+ K +S + S+ +K+ V++ + W+ PLY + N+ EH P IK + L GI NN + L I+ G RS+YRE+ L LG + ++ DVF+ Y + +++L + + D PPS + CRK F
Sbjct: 1680 TVPYLSPLVVWKELESLLENEGDQSITVSGFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEQCNKNSKVSRSCMSADSKH-----------VLIQVLWDNLKLHQDPRQPLY-ILWNTITQEHALAVPQIKEEELFDQQFLRGIVRSIKNNNVYGPVSQILDCIKQVPGRTRQ---RSLYREILFLSLVALGRENIDIDVFDREYKTAYERLTPEQLNCTQICDRPPSIGVMECRKTF 1904
BLAST of C-myc promoter-binding protein vs. Ensembl Xenopus
Match: DENND4A (DENN domain containing 4A [Source:NCBI gene;Acc:100490151]) HSP 1 Score: 363.999 bits (933), Expect = 3.113e-101 Identity = 288/976 (29.51%), Postives = 460/976 (47.13%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLY-GKSAVDELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFE---KQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMR-DMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADL----NAFSYGLCNQIILE 2998
R+ +YF+++G +++ K + EEI D KEP+ D+ ++ + ++P G+ + T + ADL G +++LC+R GRDKPP+TD+ + + + K C +I+ T G AN+S S+S+ ++I ++RA ++ ++LAVTDICII+ +K E P + +V+ ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W + + P P F TFVLT + ++YGAA+ FYE +D+LT ++ + S E Q I+ ++ +CLLS WP F F + L F+ R++ + P+ +PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W YIP L ++ +P P+++G+DSR+FD + P V C+DL T +I P+ CK L L N ++ + +++ + N D F ++ + I+E FL + + + Y++YL P++ + ++ +F++ GFLKS DR+ Y + TQ++ FI E S+ ++ D LAFFD C++ D ET L++ D +SEHT + PP+ P LP+ P N NG + DL + TP + H + ++TP S P M +R +E++ A + K+ Y S W+ LL Y LWF+ LP + R L+ A +L M++ ++ PDEVCYRVL+ L Q L V L + + NA +YG N+ +LE
Sbjct: 8 RVADYFVVTGLTDSSKPLE--------EEIHFNDA--CHKTAKPKEPITDVTVIIKSLGEEVPQGYVCIDLTPTGL-SADLNNGSIRGPQIYLCYRRGRDKPPLTDLGVLYEWKERLKQGCK-----IIQATPYGRPANISGSASSQRVFITYRRAAESMTQNSLAVTDICIIIPSKGETPPHTFCKVEKNLNSSVWGSAVYLCYKKSVAKTNAVSYKAGLICRYPEEDYE---------------SFPLPESV---PLFCLPMGATIECWPSDSNYPLPVFSTFVLTGASAEKVYGAAIQFYEPYAQDQLTEKQQVHLGLLSSAEGQMDSSKSIHVNKCICLLSHWPFFDAFKKFLTFLY------RYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDTLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQIEGKRNVTWKILPKKACKNL--------------LNTLCNLYQQLAELQHRPREEAFMELAMNDYD-FNYGKRMHQLDMEIQEAFLCFMASILKGYRSYLRPITQAPSETATDASSLFELQGFLKSRDRSHHKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVEKADVDRPGET----RLIELDESHRSEHTVFITPPE-------------IPH-------LPNGEEPPKNYSYNGFPVLILDL-FDTPDGLMK----SHKLSTKVTTPCSPSP-------------------------MFRRTKQEIRSAHKIAKQ--YSSIPQMWSRCLLRHCYGLWFICLPAYVKFCHSKV---------RALRTAYDVLRKMHMKKIDSPDEVCYRVLMQLCGQYGQPVLAVKVLFEMRKVGVQPNAITYGYYNKAVLE 856 HSP 2 Score: 94.7449 bits (234), Expect = 1.445e-18 Identity = 74/240 (30.83%), Postives = 115/240 (47.92%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLYRCVTNSAAMEH--MAPGIKSR---INEALTGIT-----NNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
TV YLSP V+ KELES+L+ EG+ ++ S F+ H I++WNL+WY+ RL LP++L L+ K +S + S+ +K+ V++ + W+ PLY + N+ EH P IK + L GI NN + L I+ G RS+YRE+ L LG + ++ DVF+ Y + +++L + + D PPS + CRK F
Sbjct: 1635 TVPYLSPLVVWKELESLLENEGDQSITVSGFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEQCNKNSKVSRSCMSADSKH-----------VLIQVLWDNLKLHQDPRQPLY-ILWNTITQEHALAVPQIKEEELFDQQFLRGIVRSIKNNNVYGPVSQILDCIKQVPGRTRQ---RSLYREILFLSLVALGRENIDIDVFDREYKTAYERLTPEQLNCTQICDRPPSIGVMECRKTF 1859
BLAST of C-myc promoter-binding protein vs. Ensembl Xenopus
Match: DENND4A (DENN domain containing 4A [Source:NCBI gene;Acc:100490151]) HSP 1 Score: 362.844 bits (930), Expect = 4.482e-101 Identity = 287/974 (29.47%), Postives = 459/974 (47.13%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLY-GKSAVDELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFE---KQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADL----NAFSYGLCNQIILE 2998
R+ +YF+++G +++ K + EEI D KEP+ D+ ++ + ++P G+ + T + ADL G +++LC+R GRDKPP+TD+ + + + K C +I+ T G AN+S S+S+ ++I ++RA ++ ++LAVTDICII+ +K E P + +V+ ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W + + P P F TFVLT + ++YGAA+ FYE +D+LT ++ + S E Q I+ ++ +CLLS WP F F + L F+ + + P+ +PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W YIP L ++ +P P+++G+DSR+FD + P V C+DL T +I P+ CK L L N ++ + +++ + N D F ++ + I+E FL + + + Y++YL P++ + ++ +F++ GFLKS DR+ Y + TQ++ FI E S+ ++ D LAFFD C++ +N ET L++ D +SEHT + PP+ P LP+ P N NG + DL + TP + H + ++TP S P M +R +E++ A + K+ Y S W+ LL Y LWF+ LP + R L+ A +L M++ ++ PDEVCYRVL+ L Q L V L + + NA +YG N+ +LE
Sbjct: 8 RVADYFVVTGLTDSSKPLE--------EEIHFNDA--CHKTAKPKEPITDVTVIIKSLGEEVPQGYVCIDLTPTGL-SADLNNGSIRGPQIYLCYRRGRDKPPLTDLGVLYEWKERLKQGCK-----IIQATPYGRPANISGSASSQRVFITYRRAAESMTQNSLAVTDICIIIPSKGETPPHTFCKVEKNLNSSVWGSAVYLCYKKSVAKTNAVSYKAGLICRYPEEDYE---------------SFPLPESV---PLFCLPMGATIECWPSDSNYPLPVFSTFVLTGASAEKVYGAAIQFYEPYAQDQLTEKQQVHLGLLSSAEGQMDSSKSIHVNKCICLLSHWPFFDAFKKFLTFLYRYS-----ISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDTLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQIEGKRNVTWKILPKKACKNL--------------LNTLCNLYQQLAELQHRPREEAFMELAMNDYD-FNYGKRMHQLDMEIQEAFLCFMASILKGYRSYLRPITQAPSETATDASSLFELQGFLKSRDRSHHKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVEK---VNLETTR---LIELDESHRSEHTVFITPPE-------------IPH-------LPNGEEPPKNYSYNGFPVLILDL-FDTPDGLMK----SHKLSTKVTTPCSPSP-------------------------MFRRTKQEIRSAHKIAKQ--YSSIPQMWSRCLLRHCYGLWFICLPAYVKFCHSKV---------RALRTAYDVLRKMHMKKIDSPDEVCYRVLMQLCGQYGQPVLAVKVLFEMRKVGVQPNAITYGYYNKAVLE 853 HSP 2 Score: 87.4261 bits (215), Expect = 2.293e-16 Identity = 68/233 (29.18%), Postives = 108/233 (46.35%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLY---RCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
TV YLSP V+ KELES+L+ EG+ ++ S F+ H I++WNL+WY+ RL LP++L L+ K +S + S+ +K+ V++ + W+ PLY + + GI I NN + L I+ G RS+YRE+ L LG + ++ DVF+ Y + +++L + + D PPS + CRK F
Sbjct: 1511 TVPYLSPLVVWKELESLLENEGDQSITVSGFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEQCNKNSKVSRSCMSADSKH-----------VLIQVLWDNLKLHQDPRQPLYILWNTIKEELFDQQFLRGIVRSIK------NNNVYGPVSQILDCIKQVPGRTRQ---RSLYREILFLSLVALGRENIDIDVFDREYKTAYERLTPEQLNCTQICDRPPSIGVMECRKTF 1723
BLAST of C-myc promoter-binding protein vs. Ensembl Mouse
Match: Dennd4a (DENN/MADD domain containing 4A [Source:MGI Symbol;Acc:MGI:2142979]) HSP 1 Score: 357.451 bits (916), Expect = 2.759e-99 Identity = 284/984 (28.86%), Postives = 449/984 (45.63%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI-----WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYF--RSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMD------EFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSN----IRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHA----DLNAFSYGLCNQIILE 2998
R+ +YF+++G ++ K + EEI D KEP+ D+ ++ + ++P + + T + ADL S V +++LC++ GRDKPP+TD+ W +KQ +I+ T G AN+S S+S+ +YI ++RA +N + LAVTDICII+ +K E P + +VD ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W + P P F TFVLT + ++YGAA+ FYE E+ LT ++ S + ++ I+ ++ +CLLS WP F F + L F+ R++ + P+++PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W Y+P L ++ +P P+++G+DSR+FD + P V C+DL T +I P+ CK L L+N ++ ++ R +MD +F ++ I I+E FL + + + Y++YL P++ + ++ +F + FL+S DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + + + L++ D+ KSEHT + P P I P NGE+ L P+ N+ L PE + A N + M +R +E+K A + K +Y S W+ LL Y LWF+ LP + R L+ A +L M + ++ PDEVCYR+L+ L Q L V L + D NA +YG N+ +LE
Sbjct: 8 RVADYFVVAGLTDISKPLE--------EEIHFNDA--CHKVAKPKEPITDVSVIIKSLGEEVPRDYVCIDVTPTGLS-ADLNNGSLVGPQIYLCYKRGRDKPPLTDLGVLYDWKERLKQG-------CEIIQSTPYGRPANISGSTSSQRIYITYRRASENTTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLSNSMWGSAVYLCYKKSVAKTNTISYKAGLICRYPQEDYE---------------SFSLPESV---PLFCLPMGATIECWPPDSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYPEENLTEKQRLLLGLTSLVDGKSDSTRTIHTNKCICLLSHWPFFDAFRKFLTFLY------RYSISGPHALPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQTGDKKNVAWKILPKKPCKNL--------------MNTLNNLHQQLAKLQQ----RPRDDGLMDLAMNDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDATSLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKV---DTDKSGEVRLIELDASFKSEHTVFVTP--------------------------PEIPHLP-----NGEEPPLQYSYNGFPVLRNN---------------------LFERPEGFLQARKNKLPSKPSSPGSPSPMFRRTKQEIKSAHKIAK--RYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKV---------RALKTAYDVLKKMQLKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLE 858 HSP 2 Score: 81.6481 bits (200), Expect = 1.009e-14 Identity = 65/235 (27.66%), Postives = 108/235 (45.96%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEIL------VNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEAL--TGITNNYLSDAIEALILIRIESGENANI-MSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
TV YLSP V+ KELES+L+ EG+ A+ ++F+ H I++WNL+WY+ RL LP++L L+ K + S +KY ++ + L +++ W A + N T M H+ N+ L + + + ++D + I + + RS+YRE+ L LG + ++ D F+ Y + +L D PPS + CRK F
Sbjct: 1631 TVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWN-AHSQNRTLLFETQKYPMVHLLQKGDDSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTF 1864
BLAST of C-myc promoter-binding protein vs. Ensembl Mouse
Match: Dennd4c (DENN/MADD domain containing 4C [Source:MGI Symbol;Acc:MGI:1914769]) HSP 1 Score: 342.043 bits (876), Expect = 7.348e-95 Identity = 286/960 (29.79%), Postives = 448/960 (46.67%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQ---TSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPEN----NCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTK-----DIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLIL----IHQLRPIRLHVSELLKHADLNAFSYGLCNQIILE 2998
R+ +YF+++G ++T D +EI D + K P+ DI ++ ++ +P+G+ V+ T S YG ELFLC+R GRDKPP+TDI ++ + +I+ T G AN+ SS++S ++I ++RAP ++LAVTDIC+I+ +K E P + +VD ++ G + +CYKKS+ N ++++ +I+ P E P SV FC+P GAT+E W P P F TFVLT + ++YGAA+ FYE ++ LT +++ + S+P I ++ +CLLS WP F+ F L+FI + + P+ +PIE IS F+ + FP+PQ P IL+Q HD P+ LP +G NF L+ L E L + +L E KILL S + LTG+AEA++AMIFPF+W YIP L ++ +P P+++GVDSR+FD P+ V CIDL T ++ + N K L Y + V + Q+ + +++ +K + I+E FLR + + + Y++YL P++ + + D +FD GFLKS DR Y + TQ++ FI E S+ ++ D GLAFFD CI+ + D+ V + DS +E T++++ D S VF ++P P ++G NNLS T P K + L F P S++ S + M KR +E+K A + K Y + WA +L S Y LWF+ LP + + + R LQ A +L M + DEVCYRV++ L ++ + +R+ NA +YG N+++LE
Sbjct: 8 RVTDYFVVAGLTDTSTLLD--------QEINRTDT----NSIGPKAPITDIAVIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYRRGRDKPPLTDIGVLYEGKERLMPGCE--VIQATPYGRCANVNNSSTTSQRIFITYRRAPPVRSQNSLAVTDICVIITSKGETPPHTFCKVDKNLNCGMWGSNVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESF-----PLSPSV-------------PLFCLPMGATIECWDPQIKYPLPVFSTFVLTGSSAEKVYGAAIQFYEPYSQERLTEKQLTQLGLLTLVEKRVVSKP--INSNKCICLLSHWPFFEAFKNFLMFIYKVS-----VSGPHPLPIEKHISHFMQNIPFPSPQRPRILIQLSVHDAFILSQPVSTPLPL-------SGANFSSLLMNLGPENCATLLLLVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNTLYVADERKNINWKQLPKRPCKSLLGTLRRLYQ----QLCSVHRKPQESSAIEMTPIEADYSWQKKMTQLEMEIQETFLRFMASILKGYRSYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYTKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKL--FPDKGVERTEKVDLDS---AEDTRLIELDDS-----QRSEHTVF--------IMP-----PEPPPDDG--NNLSPQYSYTYFPRLDLKLFDSPQKLKLC-------FNRHPPGSSITNSPAL---------MAKRTKQEIKTAHKLAKRC-YTNPPQWAKYLFSHCYSLWFICLPAYV---------RVSHPKVRALQQAHDVLVKMRKTDVDPLDEVCYRVVMQLCGLWVNPVLAVRVLFEMKTARIKPNAITYGYYNKVVLE 866 HSP 2 Score: 55.0694 bits (131), Expect = 1.389e-6 Identity = 20/43 (46.51%), Postives = 31/43 (72.09%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCN 4477
++ V M++CSQC C VYD++IM GW+ +DS+L + CP+C
Sbjct: 1530 AMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTTCPFCK 1572
BLAST of C-myc promoter-binding protein vs. Ensembl Mouse
Match: Dennd4c (DENN/MADD domain containing 4C [Source:MGI Symbol;Acc:MGI:1914769]) HSP 1 Score: 341.273 bits (874), Expect = 3.566e-94 Identity = 287/970 (29.59%), Postives = 451/970 (46.49%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQ---TSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSI------------KPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEK--QQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTK-----DIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLIL----IHQLRPIRLHVSELLKHADLNAFSYGLCNQIILE 2998
R+ +YF+++G ++T D +EI D + K P+ DI ++ ++ +P+G+ V+ T S YG ELFLC+R GRDKPP+TDI ++ + +I+ T G AN+ SS++S ++I ++RAP ++LAVTDIC+I+ +K E P + +VD ++ G + +CYKKS+ N ++++ +I+ P E P SV FC+P GAT+E W P P F TFVLT + ++YGAA+ FYE ++ LT +++ + S+P I ++ +CLLS WP F+ F L+FI + + P+ +PIE IS F+ + FP+PQ P IL+Q HD P+ LP +G NF L+ L E L + +L E KILL S + LTG+AEA++AMIFPF+W YIP L ++ +P P+++GVDSR+FD P+ V CIDL T ++ + P+ CK L L ++ S + Q+ + +++ +K + I+E FLR + + + Y++YL P++ + + D +FD GFLKS DR Y + TQ++ FI E S+ ++ D GLAFFD CI+ + D+ V + DS +E T++++ D S VF ++P P ++G NNLS T P K + L F P S++ S + M KR +E+K A + K Y + WA +L S Y LWF+ LP + + + R LQ A +L M + DEVCYRV++ L ++ + +R+ NA +YG N+++LE
Sbjct: 8 RVTDYFVVAGLTDTSTLLD--------QEINRTDT----NSIGPKAPITDIAVIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYRRGRDKPPLTDIGVLYEGKERLMPGCE--VIQATPYGRCANVNNSSTTSQRIFITYRRAPPVRSQNSLAVTDICVIITSKGETPPHTFCKVDKNLNCGMWGSNVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESF-----PLSPSV-------------PLFCLPMGATIECWDPQIKYPLPVFSTFVLTGSSAEKVYGAAIQFYEPYSQERLTEKQLTQLGLLTLVEKRVVSKP--INSNKCICLLSHWPFFEAFKNFLMFIYKVS-----VSGPHPLPIEKHISHFMQNIPFPSPQRPRILIQLSVHDAFILSQPVSTPLPL-------SGANFSSLLMNLGPENCATLLLLVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNTLYVADERKNINWKQLPKRPCKSL--------------LGTLRRLYQQLCSVHRKPQESSAIEMTPIEADYSWQKKMTQLEMEIQETFLRFMASILKGYRSYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYTKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKL--FPDKGVERTEKVDLDS---AEDTRLIELDDS-----QRSEHTVF--------IMP-----PEPPPDDG--NNLSPQYSYTYFPRLDLKLFDSPQKLKLC-------FNRHPPGSSITNSPAL---------MAKRTKQEIKTAHKLAKRC-YTNPPQWAKYLFSHCYSLWFICLPAYV---------RVSHPKVRALQQAHDVLVKMRKTDVDPLDEVCYRVVMQLCGLWVNPVLAVRVLFEMKTARIKPNAITYGYYNKVVLE 866 HSP 2 Score: 86.6557 bits (213), Expect = 3.267e-16 Identity = 68/231 (29.44%), Postives = 107/231 (46.32%), Query Frame = 2
Query: 4616 YLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGE---SLSAASQSSRNKYEIL----VNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRI--NEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
YLSP VLRKELES+L+ EG+ + S F+ +H I++WNL+WY+ RL LP++L + G LS+ SQ S+ Y L +NL +++ W ++ A + I+ I N+ L I N LS ++ RS+YRE+ L LG + ++ + F+ Y ++ L + ++ D PPS +CRK F
Sbjct: 1684 YLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNGGVQLPLSSLSQDSKLVYIQLLWDNINLHQEPGEPLYVSWRNLNSEKKPSLLSEQQQAASALVETIRQSIQQNDVLKPI--NLLSQQMKP-----------GTKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGLAYRSLPSESLERLQRIDAPPSISVEWCRKCF 1901 HSP 3 Score: 55.4546 bits (132), Expect = 1.033e-6 Identity = 20/43 (46.51%), Postives = 31/43 (72.09%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCN 4477
++ V M++CSQC C VYD++IM GW+ +DS+L + CP+C
Sbjct: 1481 AMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTTCPFCK 1523
BLAST of C-myc promoter-binding protein vs. Ensembl Mouse
Match: Dennd4c (DENN/MADD domain containing 4C [Source:MGI Symbol;Acc:MGI:1914769]) HSP 1 Score: 341.273 bits (874), Expect = 4.314e-94 Identity = 287/970 (29.59%), Postives = 451/970 (46.49%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQ---TSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSI------------KPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEK--QQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTK-----DIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLIL----IHQLRPIRLHVSELLKHADLNAFSYGLCNQIILE 2998
R+ +YF+++G ++T D +EI D + K P+ DI ++ ++ +P+G+ V+ T S YG ELFLC+R GRDKPP+TDI ++ + +I+ T G AN+ SS++S ++I ++RAP ++LAVTDIC+I+ +K E P + +VD ++ G + +CYKKS+ N ++++ +I+ P E P SV FC+P GAT+E W P P F TFVLT + ++YGAA+ FYE ++ LT +++ + S+P I ++ +CLLS WP F+ F L+FI + + P+ +PIE IS F+ + FP+PQ P IL+Q HD P+ LP +G NF L+ L E L + +L E KILL S + LTG+AEA++AMIFPF+W YIP L ++ +P P+++GVDSR+FD P+ V CIDL T ++ + P+ CK L L ++ S + Q+ + +++ +K + I+E FLR + + + Y++YL P++ + + D +FD GFLKS DR Y + TQ++ FI E S+ ++ D GLAFFD CI+ + D+ V + DS +E T++++ D S VF ++P P ++G NNLS T P K + L F P S++ S + M KR +E+K A + K Y + WA +L S Y LWF+ LP + + + R LQ A +L M + DEVCYRV++ L ++ + +R+ NA +YG N+++LE
Sbjct: 8 RVTDYFVVAGLTDTSTLLD--------QEINRTDT----NSIGPKAPITDIAVIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYRRGRDKPPLTDIGVLYEGKERLMPGCE--VIQATPYGRCANVNNSSTTSQRIFITYRRAPPVRSQNSLAVTDICVIITSKGETPPHTFCKVDKNLNCGMWGSNVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESF-----PLSPSV-------------PLFCLPMGATIECWDPQIKYPLPVFSTFVLTGSSAEKVYGAAIQFYEPYSQERLTEKQLTQLGLLTLVEKRVVSKP--INSNKCICLLSHWPFFEAFKNFLMFIYKVS-----VSGPHPLPIEKHISHFMQNIPFPSPQRPRILIQLSVHDAFILSQPVSTPLPL-------SGANFSSLLMNLGPENCATLLLLVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNTLYVADERKNINWKQLPKRPCKSL--------------LGTLRRLYQQLCSVHRKPQESSAIEMTPIEADYSWQKKMTQLEMEIQETFLRFMASILKGYRSYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYTKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKL--FPDKGVERTEKVDLDS---AEDTRLIELDDS-----QRSEHTVF--------IMP-----PEPPPDDG--NNLSPQYSYTYFPRLDLKLFDSPQKLKLC-------FNRHPPGSSITNSPAL---------MAKRTKQEIKTAHKLAKRC-YTNPPQWAKYLFSHCYSLWFICLPAYV---------RVSHPKVRALQQAHDVLVKMRKTDVDPLDEVCYRVVMQLCGLWVNPVLAVRVLFEMKTARIKPNAITYGYYNKVVLE 866 HSP 2 Score: 87.0409 bits (214), Expect = 2.553e-16 Identity = 68/231 (29.44%), Postives = 107/231 (46.32%), Query Frame = 2
Query: 4616 YLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGE---SLSAASQSSRNKYEIL----VNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRI--NEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
YLSP VLRKELES+L+ EG+ + S F+ +H I++WNL+WY+ RL LP++L + G LS+ SQ S+ Y L +NL +++ W ++ A + I+ I N+ L I N LS ++ RS+YRE+ L LG + ++ + F+ Y ++ L + ++ D PPS +CRK F
Sbjct: 1733 YLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNGGVQLPLSSLSQDSKLVYIQLLWDNINLHQEPGEPLYVSWRNLNSEKKPSLLSEQQQAASALVETIRQSIQQNDVLKPI--NLLSQQMKP-----------GTKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGLAYRSLPSESLERLQRIDAPPSISVEWCRKCF 1950 HSP 3 Score: 55.4546 bits (132), Expect = 1.127e-6 Identity = 20/43 (46.51%), Postives = 31/43 (72.09%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCN 4477
++ V M++CSQC C VYD++IM GW+ +DS+L + CP+C
Sbjct: 1530 AMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTTCPFCK 1572
BLAST of C-myc promoter-binding protein vs. Ensembl Mouse
Match: Dennd4b (DENN/MADD domain containing 4B [Source:MGI Symbol;Acc:MGI:2446201]) HSP 1 Score: 306.22 bits (783), Expect = 8.411e-84 Identity = 246/929 (26.48%), Postives = 409/929 (44.03%), Query Frame = 2
Query: 326 EPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP--LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXX---XXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPEN----NCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGN---------VMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTK-----DIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPD--PVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILI-HQLRPI-RLHVSELLKHADL--NAFSYGLCNQIILEQE 3004
EP+ D+ ++ ++P G+ +Q T + H +L G + +C+R GRDKPP+ ++ ++ + + +++ T HSANL+ Y+ ++RA + A + L +TD+C++L +K E P Y R+ ++ G + +CYK + K N L ++ E++ P E LPE + FC+P GAT+E W P P F TFVLT +++YGAA+ FYE E + + + + R++ +LSRWP F F L F+ + + P+ +P+E IS F+H V FP+PQ P IL+Q +D P+ LP +G +F L++ L E I L + +LTE K+L+ S LT + EAL++MIFP W YIP L ++ +P P+++G+ S +FD P V C+DL T ++ E + + L + Y QQ+ + TG + D + +R + ++ FLR + + + Y+N+L P++ + ++ D +F + GFLKS +R+ LY + TQ++S FI E S+ + L FFD C+ + E L++ + + SE T + PP+ PV+ ++P + C D P + + + E+ ++ + LP+ S S P S P +R +E+K A+ M +++ WA LL Y LWFL LP + V R L A +L M ++ LPDEVCYRVL+ L H +P+ + V ++ A + N +YG N+ +LE +
Sbjct: 56 EPITDVAVIARALGEEVPQGYTCIQ-TSAGGHPLELSAGLLGGTQPVICYRRGRDKPPLVELGVLYEGKERP--KLGFQVLDTTPYSHSANLAPPGPGHPRTYLMYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNE---------------AFPLPESV---PVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLMSAVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYS-----VSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSPLPL-------SGASFLQLLQNLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQKEEKKPLSARTLPRRPYKLLLATLTSLY--------------QQLDQTYTGPEEEASLEFLLTDYEAVCGRRTRLEREVQGAFLRFMACLLKGYRNFLRPLTQAPSEGSRDVDNLFYLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVDKVHP-EQEKPEPTPLVELEELSGSELTVFITPPEEPPVLEGSESTP------QYCYD-GFPELK---AELFESPQEQQGA-------LPVPG---------PSRSAPSSPAP---------------------------RRTKQEMKVAQRMAQKSATVPEL-WARCLLGHCYGLWFLCLPAYVRSVPSRV---------RALHTAYHVLREMENRKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRRAGIVPNTITYGYYNKAVLESK 873 HSP 2 Score: 110.538 bits (275), Expect = 1.817e-23 Identity = 101/370 (27.30%), Postives = 154/370 (41.62%), Query Frame = 2
Query: 4304 DSPAAAAAPCIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYC-----------NDSNRTHSNSPSYRFT---------------PKLN---FLVYINHPDPQNGKINTQSLAYTNTV-NYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWEFAS----TSNPLYRC--VTNSAAMEHMAPGIK------SRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKY--QAYVKTHDNPPSEQTLFCRKFF 5278
D+P A P S+ + M++CS C C VYD++IM GW+ +DS+L + CP+C +R + SP P L+ F + ++ P NG + + S N YLSP VLRKELES+++ EG L E H I++WNLLWY+ RL LP+ L + SQ S+ L V V L W+ + + PLY V + + PG + + L + N + A+ L+L + + R IYRE+ L A LG + V+ F+ Y S + +L + + P+ + + CRK F
Sbjct: 1149 DTPGAFQPP------SLEILMSSCSLCHACDSLVYDEEIMAGWAPDDSNLNTTCPFCACHFVPLLSVQTLDSRPSAPSPKSSLAGASGCKDAPAPGGPGPVLSDRRFCLALDQPQLCNGHMGSASRRVENGAWAYLSPLVLRKELESLVENEGSEVLALPELPAAHPIIFWNLLWYFQRLRLPSVLPGLVLASCNGP-----PPSQLSQGPSPWLTPDPA--SVHVHLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPSCLSLALLESVLRHVGLNEVHKAV-GLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRQRRAQMPTPKAIDCRKCF 1504
BLAST of C-myc promoter-binding protein vs. UniProt/SwissProt
Match: sp|Q7Z401|MYCPP_HUMAN (C-myc promoter-binding protein OS=Homo sapiens OX=9606 GN=DENND4A PE=1 SV=2) HSP 1 Score: 355.525 bits (911), Expect = 7.624e-98 Identity = 288/985 (29.24%), Postives = 450/985 (45.69%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI-----WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP-LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK-IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMD------EFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDE--NGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSN----IRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHA----DLNAFSYGLCNQIILE 2998
R+ +YF+++G ++ K + EEI D KEP+ D+ ++ + ++P + + T + ADL S V +++LC+R GRDKPP+TD+ W +KQ C +I+ T G AN+S S+S+ +YI ++RA +N + LAVTDICII+ +K E P + +VD ++ S G + +CYKKS+ K N +S++ +I P E LPE + FC+P GAT+E W N P P F TFVLT + ++YGAA+ FYE E+ LT ++ + S+ K I+ ++ +CLLS WP F F + L F+ R++ + P+ +PIE IS F+H V FP+PQ P IL+Q HD P+ LP +G F L++ L E + L V+ +TE KIL+ S S LT + EAL++MIFPF W Y+P L ++ +P P+++G+DSR+FD + P V C+D+ T +I P+ CK L L+N ++ ++ R +MD +F ++ I I+E FL + + + Y++YL P++ + ++ +F + FL+S DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + DM+ L++ D KSEHT + +TP I NGE+ L P+ N+ L PE + A N + + + M +R +E+K A + K +Y S W+ LL Y LWF+ LP + R L+ A +L M ++ PDEVCYR+L+ L Q L V L + D NA +YG N+ +LE
Sbjct: 8 RVADYFVVAGLTDVSKPLE--------EEIHFNDA--CHKVAKPKEPITDVSVIIKSLGEEVPQDYICIDVTPTGLS-ADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDWKERLKQG--CE-----IIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYE---------------SFSLPESV---PLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLY------RYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPL-------SGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKILPKKPCKNL--------------MNTLNNLHQQLAKLQQ----RPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKV-DMDKS--GEVRLIELDESFKSEHT---------------------------------VFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNN---------------------LFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAK--RYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKV---------RALKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLE 857 HSP 2 Score: 82.8037 bits (203), Expect = 3.197e-14 Identity = 66/238 (27.73%), Postives = 106/238 (44.54%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQ---VVVFLFWE----FASTSNPLY---RCVTNSAAMEHMAPGIKSRINEAL--TGITNNYLSDAIEALILIRIESGENANI-MSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
TV YLSP V+ KELES+L+ EG+ A+ ++F+ H I++WNL+WY+ RL LP++L + S NKY + E V++ + W+ PLY T M H+ + N+ L + + + ++D + I + + RS+YRE+ L LG + ++ D F+ Y + +L D PPS + CRK F
Sbjct: 1634 TVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLI-------------LSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTF 1858
BLAST of C-myc promoter-binding protein vs. UniProt/SwissProt
Match: sp|Q5VZ89|DEN4C_HUMAN (DENN domain-containing protein 4C OS=Homo sapiens OX=9606 GN=DENND4C PE=1 SV=3) HSP 1 Score: 341.658 bits (875), Expect = 2.149e-93 Identity = 235/735 (31.97%), Postives = 365/735 (49.66%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYK-IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITK----SIKPPENNCKYLDYXXXXXXXXXXXXXY-GLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQT-----KDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNM---------RDMNDETVNAASLLQTDSVIKSEHTKVLDPPDP 2311
R+ +YF+++G ++T D +EI D K T K P+ DI I+ ++ +P+G+ V+ T S YG ELFLC++ GRDKPP+TDI ++ + +I T G AN+ SS++S ++I ++RAP P ++LAVTDIC+I+ +K E P + +VD ++ G ++ +CYKKS+ N ++++ +I+ P E P D FC+P GAT+E W P P F TFVLT + ++YGAA+ FYE + L+ +++ + + K I ++ +CLLS WP F+ F + L+FI + + P+ +PIE IS F+ + FP+PQ P IL+Q HD P+ LP +G NF L+ L E L +++L E KILL S + LTG+AEA++AMIFPF+W YIP L ++ +P P+++GVDSR+FD P+ V CIDL T S + N K L Y LS+ K Q+ + + +F+ +K + I+E FLR + + + Y+ YL P++ + + D +FD GFLKS DR Y + TQ++ FI E S+ ++ D GLAFFD CI+ + ++ ++ L++ D KSEHT + PP+P
Sbjct: 8 RVTDYFVVAGLTDTSTLLD--------QEINRLDTKSTGP----KAPITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCE--VILATPYGRCANVNNSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDYE-----------------SFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTNKCICLLSHWPFFEAFRKFLMFIYKLS-----VSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPL-------SGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKT-----QEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAEDTRLIELDDSQKSEHTVFIMPPEP 694 HSP 2 Score: 85.8853 bits (211), Expect = 3.951e-15 Identity = 69/236 (29.24%), Postives = 109/236 (46.19%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLYRCVTN------SAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
+V YLSP VLRKELES+L+ EG+ + S F+ +H I++WNL+WY+ RL LP++L LT +G L +S S +K V + L W+ PLY N S+ + + + I +N + I L+ +++ G RS+YRE+ L LG + ++ + F+ Y + L + ++ D PPS +CRK F
Sbjct: 1684 SVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNEGVQLPLSSLSQDSKL-----------VYIQLLWDNINLHQEPREPLYVSWRNFNSEKKSSLLSEEQQETSTLVETIRQSIQHNNVLKPIN-LLSQQMKPGMKRQ---RSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSSEILERLQKIDAPPSASVEWCRKCF 1904 HSP 3 Score: 56.6102 bits (135), Expect = 3.064e-6 Identity = 41/133 (30.83%), Postives = 60/133 (45.11%), Query Frame = 2
Query: 2612 MLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILI----HQLRPIRLHVSELLKHADLNAFSYGLCNQIILE 2998
M KR +E+K A + K Y + WA L S Y LWF+ LP + + + R LQ A +L M + DEVCYRV++ L H + +R+ NA +YG N+++LE
Sbjct: 745 MAKRTKQEIKTAHKLAKRC-YTNPPQWAKCLFSHCYSLWFICLPAYV---------RVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTARIKPNAITYGYYNKVVLE 867 HSP 4 Score: 55.4546 bits (132), Expect = 6.478e-6 Identity = 20/43 (46.51%), Postives = 31/43 (72.09%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCN 4477
++ V M++CSQC C VYD++IM GW+ +DS+L + CP+C
Sbjct: 1484 AMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCK 1526
BLAST of C-myc promoter-binding protein vs. UniProt/SwissProt
Match: sp|A6H8H2|DEN4C_MOUSE (DENN domain-containing protein 4C OS=Mus musculus OX=10090 GN=Dennd4c PE=1 SV=1) HSP 1 Score: 341.273 bits (874), Expect = 2.494e-93 Identity = 287/970 (29.59%), Postives = 451/970 (46.49%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQ---TSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSI------------KPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEK--QQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTK-----DIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLIL----IHQLRPIRLHVSELLKHADLNAFSYGLCNQIILE 2998
R+ +YF+++G ++T D +EI D + K P+ DI ++ ++ +P+G+ V+ T S YG ELFLC+R GRDKPP+TDI ++ + +I+ T G AN+ SS++S ++I ++RAP ++LAVTDIC+I+ +K E P + +VD ++ G + +CYKKS+ N ++++ +I+ P E P SV FC+P GAT+E W P P F TFVLT + ++YGAA+ FYE ++ LT +++ + S+P I ++ +CLLS WP F+ F L+FI + + P+ +PIE IS F+ + FP+PQ P IL+Q HD P+ LP +G NF L+ L E L + +L E KILL S + LTG+AEA++AMIFPF+W YIP L ++ +P P+++GVDSR+FD P+ V CIDL T ++ + P+ CK L L ++ S + Q+ + +++ +K + I+E FLR + + + Y++YL P++ + + D +FD GFLKS DR Y + TQ++ FI E S+ ++ D GLAFFD CI+ + D+ V + DS +E T++++ D S VF ++P P ++G NNLS T P K + L F P S++ S + M KR +E+K A + K Y + WA +L S Y LWF+ LP + + + R LQ A +L M + DEVCYRV++ L ++ + +R+ NA +YG N+++LE
Sbjct: 8 RVTDYFVVAGLTDTSTLLD--------QEINRTDT----NSIGPKAPITDIAVIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYRRGRDKPPLTDIGVLYEGKERLMPGCE--VIQATPYGRCANVNNSSTTSQRIFITYRRAPPVRSQNSLAVTDICVIITSKGETPPHTFCKVDKNLNCGMWGSNVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESF-----PLSPSV-------------PLFCLPMGATIECWDPQIKYPLPVFSTFVLTGSSAEKVYGAAIQFYEPYSQERLTEKQLTQLGLLTLVEKRVVSKP--INSNKCICLLSHWPFFEAFKNFLMFIYKVS-----VSGPHPLPIEKHISHFMQNIPFPSPQRPRILIQLSVHDAFILSQPVSTPLPL-------SGANFSSLLMNLGPENCATLLLLVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNTLYVADERKNINWKQLPKRPCKSL--------------LGTLRRLYQQLCSVHRKPQESSAIEMTPIEADYSWQKKMTQLEMEIQETFLRFMASILKGYRSYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYTKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKL--FPDKGVERTEKVDLDS---AEDTRLIELDDS-----QRSEHTVF--------IMP-----PEPPPDDG--NNLSPQYSYTYFPRLDLKLFDSPQKLKLC-------FNRHPPGSSITNSPAL---------MAKRTKQEIKTAHKLAKRC-YTNPPQWAKYLFSHCYSLWFICLPAYV---------RVSHPKVRALQQAHDVLVKMRKTDVDPLDEVCYRVVMQLCGLWVNPVLAVRVLFEMKTARIKPNAITYGYYNKVVLE 866 HSP 2 Score: 86.6557 bits (213), Expect = 2.285e-15 Identity = 68/231 (29.44%), Postives = 107/231 (46.32%), Query Frame = 2
Query: 4616 YLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGE---SLSAASQSSRNKYEIL----VNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRI--NEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
YLSP VLRKELES+L+ EG+ + S F+ +H I++WNL+WY+ RL LP++L + G LS+ SQ S+ Y L +NL +++ W ++ A + I+ I N+ L I N LS ++ RS+YRE+ L LG + ++ + F+ Y ++ L + ++ D PPS +CRK F
Sbjct: 1684 YLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNGGVQLPLSSLSQDSKLVYIQLLWDNINLHQEPGEPLYVSWRNLNSEKKPSLLSEQQQAASALVETIRQSIQQNDVLKPI--NLLSQQMKP-----------GTKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGLAYRSLPSESLERLQRIDAPPSISVEWCRKCF 1901 HSP 3 Score: 55.4546 bits (132), Expect = 7.225e-6 Identity = 20/43 (46.51%), Postives = 31/43 (72.09%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCN 4477
++ V M++CSQC C VYD++IM GW+ +DS+L + CP+C
Sbjct: 1481 AMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTTCPFCK 1523
BLAST of C-myc promoter-binding protein vs. UniProt/SwissProt
Match: sp|Q3U1Y4|DEN4B_MOUSE (DENN domain-containing protein 4B OS=Mus musculus OX=10090 GN=Dennd4b PE=1 SV=2) HSP 1 Score: 306.22 bits (783), Expect = 6.200e-83 Identity = 246/929 (26.48%), Postives = 409/929 (44.03%), Query Frame = 2
Query: 326 EPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNP--LYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXX---XXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPEN----NCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGN---------VMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTK-----DIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPD--PVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILI-HQLRPI-RLHVSELLKHADL--NAFSYGLCNQIILEQE 3004
EP+ D+ ++ ++P G+ +Q T + H +L G + +C+R GRDKPP+ ++ ++ + + +++ T HSANL+ Y+ ++RA + A + L +TD+C++L +K E P Y R+ ++ G + +CYK + K N L ++ E++ P E LPE + FC+P GAT+E W P P F TFVLT +++YGAA+ FYE E + + + + R++ +LSRWP F F L F+ + + P+ +P+E IS F+H V FP+PQ P IL+Q +D P+ LP +G +F L++ L E I L + +LTE K+L+ S LT + EAL++MIFP W YIP L ++ +P P+++G+ S +FD P V C+DL T ++ E + + L + Y QQ+ + TG + D + +R + ++ FLR + + + Y+N+L P++ + ++ D +F + GFLKS +R+ LY + TQ++S FI E S+ + L FFD C+ + E L++ + + SE T + PP+ PV+ ++P + C D P + + + E+ ++ + LP+ S S P S P +R +E+K A+ M +++ WA LL Y LWFL LP + V R L A +L M ++ LPDEVCYRVL+ L H +P+ + V ++ A + N +YG N+ +LE +
Sbjct: 45 EPITDVAVIARALGEEVPQGYTCIQ-TSAGGHPLELSAGLLGGTQPVICYRRGRDKPPLVELGVLYEGKERP--KLGFQVLDTTPYSHSANLAPPGPGHPRTYLMYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNE---------------AFPLPESV---PVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLMSAVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYS-----VSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSPLPL-------SGASFLQLLQNLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQKEEKKPLSARTLPRRPYKLLLATLTSLY--------------QQLDQTYTGPEEEASLEFLLTDYEAVCGRRTRLEREVQGAFLRFMACLLKGYRNFLRPLTQAPSEGSRDVDNLFYLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVDKVHP-EQEKPEPTPLVELEELSGSELTVFITPPEEPPVLEGSESTP------QYCYD-GFPELK---AELFESPQEQQGA-------LPVPG---------PSRSAPSSPAP---------------------------RRTKQEMKVAQRMAQKSATVPEL-WARCLLGHCYGLWFLCLPAYVRSVPSRV---------RALHTAYHVLREMENRKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRRAGIVPNTITYGYYNKAVLESK 862 HSP 2 Score: 110.153 bits (274), Expect = 1.332e-22 Identity = 101/370 (27.30%), Postives = 154/370 (41.62%), Query Frame = 2
Query: 4304 DSPAAAAAPCIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYC-----------NDSNRTHSNSPSYRFT---------------PKLN---FLVYINHPDPQNGKINTQSLAYTNTV-NYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWEFAS----TSNPLYRC--VTNSAAMEHMAPGIK------SRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKY--QAYVKTHDNPPSEQTLFCRKFF 5278
D+P A P S+ + M++CS C C VYD++IM GW+ +DS+L + CP+C +R + SP P L+ F + ++ P NG + + S N YLSP VLRKELES+++ EG L E H I++WNLLWY+ RL LP+ L + SQ S+ L V V L W+ + + PLY V + + PG + + L + N + A+ L+L + + R IYRE+ L A LG + V+ F+ Y S + +L + + P+ + + CRK F
Sbjct: 1138 DTPGAFQPP------SLEILMSSCSLCHACDSLVYDEEIMAGWAPDDSNLNTTCPFCACHFVPLLSVQTLDSRPSAPSPKSSLAGASGCKDAPAPGGPGPVLSDRRFCLALDQPQLCNGHMGSASRRVENGAWAYLSPLVLRKELESLVENEGSEVLALPELPAAHPIIFWNLLWYFQRLRLPSVLPGLVLASCNGP-----PPSQLSQGPSPWLTPDPA--SVHVHLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPSCLSLALLESVLRHVGLNEVHKAV-GLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRQRRAQMPTPKAIDCRKCF 1493
BLAST of C-myc promoter-binding protein vs. UniProt/SwissProt
Match: sp|Q9W3D3|CRAG_DROME (DENN domain-containing protein Crag OS=Drosophila melanogaster OX=7227 GN=Crag PE=1 SV=3) HSP 1 Score: 306.22 bits (783), Expect = 1.295e-82 Identity = 268/976 (27.46%), Postives = 468/976 (47.95%), Query Frame = 2
Query: 179 LNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAAS-FCMPWGATLESW-----SLNRSIPKPSFLTFVLTNVNYN-RMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQW--DHDHPIGIQLPTDA-LSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGES-IRECFLRAVILMFRNYQNYLIPVSFSQT-----KDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNI--RNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLP-DEVCYRVLLIL--IHQLRPIRLHVSELLKHADL--NAFSYGLCNQIILEQEQQWSQKLSNLS 3037
+ ++RI +YF+++G + L + + + A I EP+ DI + ++P+G+ I+ +T + +G + ++ FR G+D+PP+ DI + + + ++ +T G AN+++SS+ ++ ++RA + P + L VT++C+I+ +K E P A+ + ++ + +G + +CYKKSM + +S++PEI+ P P ++C + FC+P GA+LE+W + R P F TFVLT + ++YG+A+ FYE+ DE +L+ E+ E + ++ +++CLLS P TF++ L ++ + + IP+E +I+Q L V FP AP+I LQ + + I + P D+ L R G G F+ L++ L + + + + LTEQKIL+ S + LT +AEA+++++FPFKW YIP L ++ +P PYLIGVDSRFFD + P V CIDL T +I E+ ++L + ++ + + E + + ++ N +D RKRE + E I+E FL + + R Y+++L+P+S + + +F + FL+S D++ + ++ + TQ++ FI ERS+ ++ D GL+FFD C + + + DET L+ D+ SE TK + PPD V +P P L N E+ L P + S K +LS FL + ++++ S I R + +K+S K A + + S Y A + Y L+FL LP ++ + G IL+ A +L + +RL + DE CYR+++ L IH L + + + L+K + + NA +YG N+ +L E QW Q + +S
Sbjct: 1 MEEKRIADYFVVAGMPENPQL--LQENSFNDSGRLRAATTI--------EPITDIGVYFPLLGEEVPEGYEILSHTPTGLQANLNHGSVRTTDCYIYFRRGKDRPPLVDIGVLYDGHERIMSDAE--IVAETPGGRVANVNNSSAK-TFLTYRRARADMPCNELVVTELCVIVQSKGERAPHAFCLIYKTLNKGYVGSDVYLCYKKSMYRPKHISYKPEILLRYPTFD-----------------HTDFPLNLCPSVPLFCLPMGASLEAWPHVNGTEKRKPISPVFSTFVLTVSDGTYKVYGSALTFYEDYDESKLSAEQKELLGWDEEFGAQ--HSLHMIKAICLLSHHPFGDTFDKWLKYL----HRMVLYDVNIPIPVERYITQLLDEVPFP---APSIHLQLSSESNDRILLTQPEDSPLPRSGAG--FHILLQNLGTDNCLHVLLLALTEQKILIHSLRPATLTAVAEAIVSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPTDVTCIDLDTNNISLCESQ-RHLSPKLLPKRAARL--------LRQTLTELENAKPISYDSTNSLDRDIRKRKRELVLEQRIQEAFLLFMASILRGYRDFLVPISKAPSVGATDPSALFQLKAFLRSRDKSHQKFFELMMKTQMFIRFIEERSFVSDGDHGLSFFDECAEKVGNY-DETPAQLHLVDWDTGQNSERTKYIFPPDSV------TPAGSQPGGGGGGLAY------------NYENFTLQ------PELLQSTKKT------ALSK------FLQLQLNASLSPGSPIARRTKHEIKLSQ--------KMASRCQQHPEAWSKYLLA-----TCYSLYFLILPSMV------LDPRHAGKEPEILRAAYDVL--VRASRLKITCDEFCYRIMMQLCGIHNLPVLAVRLHYLMKRSGVQANALTYGFYNRCVL--ESQWPQDSTTIS 866 HSP 2 Score: 154.836 bits (390), Expect = 3.702e-36 Identity = 117/360 (32.50%), Postives = 178/360 (49.44%), Query Frame = 2
Query: 4244 SLGAIRLPTGKYWPDSQIDGDSPAAAAAPCIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDP-QNGK---INTQSLAYTNTVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEIL-VNLTGFEQVV---VFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRE-LFCLITAVLGNQVNYDVFNFTYNSPWQQL-KRKYQAYVKTHDNPPSEQTLFCRKFFRPLQL 5293
S GA+ + PD+ S AA C + + +TTCSQC NC VYD++IM+GW+ DS+L + C CN + R + DP Q+GK N S + TV YL+P VLRKELE++L QEG+IAL+K EF+ EH I+YWNLLW R+ THL L + + E + S+ + L NL+ + ++L + ++PL + + A + K+ I + ++ I N + ++ L R + N S S YR+ LF +TA+ + V+ F+ Y + + +L +R+ Y + D PPS T+FCR +FRPL L
Sbjct: 1328 STGALHMHAFPAVPDNLYSLTSENAADRDC-----DVLIQLTTCSQCHNCSVLVYDEEIMSGWTAEDSNLNTTCHACNKLTVPFLSVQIERQVEE------SEQSDPLQDGKEQIANGNSHKTSLTVPYLNPLVLRKELENILTQEGDIALIKPEFVDEHPIIYWNLLWLMERIESKTHLPE-LCLPVPSDKEHIDPLSKVKTVHIQCLWDNLSLHTEASGPPMYLLYRETQPTSPLIKALLTDQAQLN-----KNVIQQIISAIRCNDFATPLKRLANERHKLKSNGVERSHSFYRDILFLALTAIGRSNVDLATFHREYAAVFDKLTERECNMYYRNQDLPPSASTIFCRAYFRPLLL 1670
BLAST of C-myc promoter-binding protein vs. TrEMBL
Match: A0A4E0RJU1 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_002338 PE=4 SV=1) HSP 1 Score: 453.366 bits (1165), Expect = 3.546e-126 Identity = 283/769 (36.80%), Postives = 435/769 (56.57%), Query Frame = 2
Query: 179 LNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKS---ELCLPE----------DICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFY--------------------XXXXXXXXXXXXXAYFRSKNETQTSEPYK-----------IYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLP--TDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGC--IDLITKSIKPPENNCK---YLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVM--------------DEFTILRKREN----------IGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDIMFDIDGFLKSV-DRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDR-CIKNMRDMNDET-VNAASL 2251
LN R+I EYF++ G ++ ++ S + EEI+ DV + DF ++EP+VDIKIV+ ++P G+H ++ T+S + +A++ G+ DE++LC+R GRDKPPITD+ F N +D I KT G SAN SS +P+Y++++RAP + +D LAVTD+CII+ +K+E CPPA+++V S+ +PL + + +C++KS++KQ ++++ PE+++ EP V++ DR +++ E +P DI A+FC+PWGA LESWS+ + P+P+F TFVLTN +Y R+YG A FY E + + + + ++ E + E K + ++++CLLSRW F L F+ + +P IP E ++S FL V FP+ P+++++ PI + P DA+S+ E F+ L+ L V+ IQL V MLTEQKILLTS LT I EAL +MIFP +W+VVYIPF+Y+ CIH+IQSPSPYLIGVDSRFFDFFRLP G G +DL T++ K PE C LD K LPK LK LK LS ++++ + + T NV+ +E T+L +R+ IG I+ F+ + + + YQ +LIPV ++ +D++F+ GFLK + +++ R Y +F+TQ W+NF+ +RSY + D+ L+ FD ++ D DE+ V + SL
Sbjct: 9 LNTRKIAEYFVVCGLPDSPNPFNSSDVITHAEEIIIPDVSV--DFTMFQEPIVDIKIVSVRDNEEIPYGYHPIKRTHSGRFKANIKGRIG-DEVYLCYRRGRDKPPITDLAMFTDSPSNRLLEDA-KKITKTCGGKSANFRSSLIHPVYLSYRRAPKESGIDRLAVTDMCIIIPSKHETCPPAFNQVADSLNSNPLVNQMYLCFRKSLIKQYIIAYDPEVLFWYRV--REPGVELEMTDREGLETSSQENTVPNNRLTHDSLDPDIRQVANFCLPWGAALESWSVEQEPPEPNFFTFVLTNESYQRLYGVAFTFYEPYDVSQLDMDKCYRLGVDPELLVSRKSQSSVLDEADAEEEARFREIQKHFFPARIGDRVVGVTKTMCLLSRWSFPVAFTNFLAFLYSRWQPAAKDDP---IPFERYLSYFLCEVPFPSQSMPHVMVEL-CAAPILLNFPDDNDAVSKC---EPFFFLLDCLGVDLTIQLLVQMLTEQKILLTSVRPFLLTQIGEALTSMIFPLRWTVVYIPFIYIGCIHVIQSPSPYLIGVDSRFFDFFRLPPGGGVTYVDLDTRNFKLPEPGCSGQPVLD-AKSLPKKPLKQLKAALSKLFARIITLRPSR--SRQTTNVLFRCMFSQAGSQLANNELTVLERRQQWLREFAEMATIGLQIKNTFMHFMAQLLKCYQRFLIPVRQAE-RDVLFNASGFLKEIAEKHSRPFYVTLFETQQWANFVRDRSYVSARDEELSRFDSYMVRLFGDSADESPVGSQSL 760 HSP 2 Score: 89.3521 bits (220), Expect = 1.210e-13 Identity = 61/191 (31.94%), Postives = 92/191 (48.17%), Query Frame = 2
Query: 4352 IHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVY-------INHPDPQNG--------KINTQ-----SLAYTN-------------------TVNYLSPFVLRKELESVLDQEGEIALLKSE----FLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWL 4795
++V MTTC+ C C+R V+D++IM WS ++++ CP+C+ + F P + + ++ P P++G +TQ SL TN T +YLSP VLRK LE+V+ EG+ +L FLY+H L W+L+WY R+GL T+LL L WL
Sbjct: 1720 LNVIMTTCNTCPTCKRFVHDEEIMASWSSDENEYSIPCPFCDGT-----------FVPLITVRILGDVYTPNLDSPVPESGGEVISLVASGSTQMRRRGSLCSTNGSGARRRHSPFTSRGLMEFTQHYLSPLVLRKSLETVILHEGDESLRHQSPGQCFLYKHEELTWSLVWYTQRIGLLTNLLDALPSWL 1899 HSP 3 Score: 67.3958 bits (163), Expect = 5.312e-7 Identity = 55/186 (29.57%), Postives = 88/186 (47.31%), Query Frame = 2
Query: 2507 SLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVS---MLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHV------EETAGLKETGLA--ERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADLNAFSYGLCNQII--LEQEQQWSQKL 3025
SL T D+ PF+ + S + + + R + V +L+R EL Q K A WA HL+SS Y LWF+ LP + V + +E LA L A++L + + + D+V R++L L++Q RP ++++ LL N+ S GL N I E+E+Q ++L
Sbjct: 924 SLMTSDTPSPFISRSSLSMALSLTGLPTRYPLPVGGSVILRRSPLELHQTAEFVKRASVEGGLVWAHHLISSMYTLWFMLLPSYLASVYAATTEQRPPADQECRLAVLNETLSNAVLLAGRLQDDGVLCHDQVMMRIILALVYQHRPSDINLTTLLDSPLWNSSSMGLVNLIFKTFEKERQDKERL 1109
BLAST of C-myc promoter-binding protein vs. TrEMBL
Match: A0A1S3I543 (C-myc promoter-binding protein OS=Lingula unguis OX=7574 GN=LOC106161083 PE=4 SV=1) HSP 1 Score: 400.979 bits (1029), Expect = 1.969e-109 Identity = 291/919 (31.66%), Postives = 456/919 (49.62%), Query Frame = 2
Query: 179 LNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVM---DEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFS---QTKDI--MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPR-KVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQ 2905
++++R+ +YF+++G ++ D + E I+ + H EP+ DI ++ + + PDGF ++ T + ADL +G E+++C + GRDKPPITDI ++ + ++ T G AN+++S+S+ YI ++RA +NAP D LAVTD+CIIL NK E+ P A+ ++ ++ + +G + +CYKKSM K NVL+++P I+Y PA +E E LP + FCMP GA +E W PKP F TFVLT ++++YGAAV FYE +E++LT+E+ E + ++ ++S+CLLS WP F TF + L + K + +PIE +IS F+ V FP+P P ILLQ D I + P D R +G +F L++ L + + + ++ L E KI++ S + LT +AEA++ +IFPF+W YIP L ++ +P+P+++GVDSR+FD + P V C+DL T +I E+ K ++Y + K V L N + + Q + G + +F +K + + +I+E FLR + + + Y+NYL P++ + +T D +FD+ GFLKS DR + + + TQ + FI ERS+ +E + L FFD C + + DE + L++ D KSE T V+ PPDP +S R K FP+ L +L L +DNN + TP P P M SN E+K A+ ++ + WA LL+ +Y LWF+ LP + HV T R L++A +L M RL PDEVCYRV++ L Q
Sbjct: 1 MDEKRVADYFVVAGLTDQILPLDE----FSNEAILKPN--------HKPEPITDIAVIVKSLGEQCPDGFTCIEKTPTG-FPADLNHGSLRSPEVYICIQRGRDKPPITDIGVLYEGKERVLPGCE--VMHLTPYGRPANVNNSNSSRTYITYRRASENAPSDTLAVTDVCIILTNKGEVAPHAFCQIPKTLNKGMVGSDVYLCYKKSMTKTNVLAYKPGIVYRYPAVDSE---------------EFPLPASV---PLFCMPMGAMIECWPAKAHRPKPVFSTFVLTGDRWDKVYGAAVTFYETYNEEKLTSEQRRNLGLLEEHNSQPKMLVHANKSICLLSHWPFFDTFKRFLTVLF----KMTLNGIESPVPIERYISHFMWDVPFPSPSRPRILLQLGSDL-ISLSQPEDTPLR-QSGASFSTLLKNLGPDNCMNVLLFSLLEHKIVIHSLRPAVLTSVAEAVVTLIFPFQWQCPYIPLCPLGFSEVLSAPTPFIVGVDSRYFDLYDPPPDVTCVDLDTNTISQSEDK-KSMNYKILPKKPVRV-----LRNTLMHLCEQLQTQSPATDVGQMSLLDSDFKKKKKEQRMETAIQEAFLRFMASILKGYKNYLKPITKAPNDRTTDASSLFDMSGFLKSRDRAYQKFFTQMMKTQNFCRFIEERSFTSEKNSNLVFFDECTEKV----DENKDEPRLIEIDDSQKSERTVVITPPDPADFPEGSSFRYKGFPE-LKEELFL-------------KQDNN------------------------TFKTPSKQGP----CPNGPMARRSNY----------------EIKSAQKTAQKHAE-TPVLWAKCLLAHTYSLWFIHLPAYV-HVTPTKN--------RALRIAYNVLIKMQTARLQPPDEVCYRVMMQLCGQ 802 HSP 2 Score: 123.25 bits (308), Expect = 5.694e-24 Identity = 75/238 (31.51%), Postives = 128/238 (53.78%), Query Frame = 2
Query: 4610 VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILV-------NLTGFEQV--VVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQL 5293
V YLSP VLRKELE+VL EG+++L + EFL EH I++WN++WY+ RL +P+H+ ++ +S++ +SS+ + LV N+ ++V ++ W S S + VT S A KS + + +T I N + I+ +I R +N RS+YRE+ L + G + +++D F+ Y +++L K + ++T D PP+ ++CRK F L++
Sbjct: 1854 VPYLSPLVLRKELENVLGSEGDLSLSRDEFLDEHPIIFWNMVWYFKRLDVPSHMPGYIMT-----AKSINKEKESSQQADDKLVLVRLKWDNIRLHDEVGQPMYKLWTSKSPSAAVNALVTESQAFS------KSILQQIVTSIQCNDMFSPIKIVIHERHRRNKNKRYKHRSMYREICFLSFSACGRENIDHDAFDREYKLAFRKLTPKDISRLQTDDRPPNASVIWCRKMFSELEI 2080
BLAST of C-myc promoter-binding protein vs. TrEMBL
Match: A0A2R2MPF7 (DENN domain-containing protein 4C-like OS=Lingula unguis OX=7574 GN=LOC106178677 PE=4 SV=1) HSP 1 Score: 400.593 bits (1028), Expect = 2.595e-109 Identity = 291/919 (31.66%), Postives = 456/919 (49.62%), Query Frame = 2
Query: 179 LNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVM---DEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFS---QTKDI--MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPR-KVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQ 2905
++++R+ +YF+++G ++ D + E I+ + H EP+ DI ++ + + PDGF ++ T + ADL +G E+++C + GRDKPPITDI ++ + ++ T G AN+++S+S+ YI ++RA +NAP D LAVTD+CIIL NK E+ P A+ ++ ++ + +G + +CYKKSM K NVL+++P I+Y PA +E E LP + FCMP GA +E W PKP F TFVLT ++++YGAAV FYE +E++LT+E+ E + ++ ++S+CLLS WP F TF + L + K + +PIE +IS F+ V FP+P P ILLQ D I + P D R +G +F L++ L + + + ++ L E KI++ S + LT +AEA++ +IFPF+W YIP L ++ +P+P+++GVDSR+FD + P V C+DL T +I E+ K ++Y + K V L N + + Q + G + +F +K + + +I+E FLR + + + Y+NYL P++ + +T D +FD+ GFLKS DR + + + TQ + FI ERS+ +E + L FFD C + + DE + L++ D KSE T V+ PPDP +S R K FP+ L +L L +DNN + TP P P M SN E+K A+ ++ + WA LL+ +Y LWF+ LP + HV T R L++A +L M RL PDEVCYRV++ L Q
Sbjct: 1 MDEKRVADYFVVAGLTDQILPLDE----FSNEAILKPN--------HKPEPITDIAVIVKSLGEQCPDGFTCIEKTPTG-FPADLNHGSLRSPEVYICIQRGRDKPPITDIGVLYEGKERVLPGCE--VMHLTPYGRPANVNNSNSSRTYITYRRASENAPSDTLAVTDVCIILTNKGEVAPHAFCQIPKTLNKGMVGSDVYLCYKKSMTKTNVLAYKPGIVYRYPAVDSE---------------EFPLPASV---PLFCMPMGAMIECWPAKAHRPKPVFSTFVLTGDRWDKVYGAAVTFYETYNEEKLTSEQRRNLGLLEEHNSQPKMLVHANKSICLLSHWPFFDTFKRFLTVLF----KMTLNGIESPVPIERYISHFMWDVPFPSPSRPRILLQLGSDL-ISLSQPEDTPLR-QSGASFSTLLKNLGPDNCMNVLLFSLLEHKIVIHSLRPAVLTSVAEAVVTLIFPFQWQCPYIPLCPLGFSEVLSAPTPFIVGVDSRYFDLYDPPPDVTCVDLDTNTISQSEDK-KSMNYKILPKKPVRV-----LRNTLMHLCEQLQTQSPATDVGQMSLLDSDFKKKKKEQRMETAIQEAFLRFMASILKGYKNYLKPITKAPNDRTTDASSLFDMSGFLKSRDRAYQKFFTQMMKTQNFCRFIEERSFTSEKNSNLVFFDECTEKV----DENKDEPRLIEIDDSQKSERTVVITPPDPADFPEGSSFRYKGFPE-LKEELFL-------------KQDNN------------------------TFKTPSKQGP----CPNGPMARRSNY----------------EIKSAQKTAQKHAE-TPVLWAKCLLAHTYSLWFIHLPAYV-HVTPTKN--------RALRIAYNVLIKMQTARLQPPDEVCYRVMMQLCGQ 802 HSP 2 Score: 95.9005 bits (237), Expect = 1.015e-15 Identity = 61/189 (32.28%), Postives = 99/189 (52.38%), Query Frame = 2
Query: 4610 VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILV-------NLTGFEQV--VVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ 5149
V YLSP VLRKELE+VL EG+++L + EFL EH I++WN++WY+ RL +P+H+ ++ +S++ +SS+ + LV N+ ++V ++ W S S + VT S A KS + + +T I N + I+ +I R +N RS+YRE+ L + G +
Sbjct: 1854 VPYLSPLVLRKELENVLGSEGDLSLSRDEFLDEHPIIFWNMVWYFKRLDVPSHMPGYIMT-----AKSINKEKESSQQADDKLVLVRLKWDNIRLHDEVGQPMYKLWTSKSPSAAVNALVTESQAFS------KSILQQIVTSIQCNDMFSPIKIVIHERHRRNKNKRYKHRSMYREICFLSFSACGRE 2031
BLAST of C-myc promoter-binding protein vs. TrEMBL
Match: A0A4W6DJT4 (DENN/MADD domain containing 4A OS=Lates calcarifer OX=8187 PE=4 SV=1) HSP 1 Score: 394.43 bits (1012), Expect = 3.503e-108 Identity = 325/1068 (30.43%), Postives = 501/1068 (46.91%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEK--QQILRKNTGNVMD---EFTILRKRENIGES-------IRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTI--PFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILEQEQQWSQ----------KLSNLSTSTKQPKCDSDNPDKPIAVEKEGKDEKDCDS-GRETLASANIAPEEAQ--------DSSDSGCNLIMKSDNNY 3229
R+ +YF+I+G +++ K + EE+ D K P+ D+ +V + ++P GF V++T S A+L G S ++FLCF+ GRDKPP+TD+ + + K K C +++ T +G AN+SSSSS +YI ++RAP + P +LAVTD+CII+ K E P + +VD ++ S G ++ +CYKKS+ K N ++++ ++ P E LPE + FC+P GAT+E W + P F TFVLT + ++YGAA+ FYE E+ L+ + + ++ +Y ++S+CLLS WP FQ+F L F+ R++ + P+++PIE IS F+ +V FP+ Q P IL+Q HD P+ LP +G + L+ L + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++GVDSR+FD + P + C+DL T +I ++ K L + + ++ CK + + K QQ+ N D E T+ N G+S I+E FLR + + R Y++YL+P++ + ++ +FD+ GFLKS DR+ + Y + TQ++S FI E S+ ++ D LAFFD C+ M+ E L++ D +SEHT ++PP+ LP PLP E+H H S + ++ + P P SA AS + + + ++ +R +E+K A+ M K Y S W+ LL Y LWF+ LPGL+G R L+ A +L M +L PDEVCYRVLL L Q L V L +K A + NA +YG N+ +L E W KL N+ Q K P + + D D D+ +L SAN + E DSSD G + +SD Y
Sbjct: 7 RVADYFVIAGLTDSSKPLE--------EELHFDDAGPKS--VKPKAPITDVAVVIRSLGEEVPPGFTCVESTPSGL-SAELNGASLRGPQIFLCFKRGRDKPPLTDLGVLYEWKEKLKPGCH-----IVQTTPSGRPANISSSSSQRIYITYRRAPKSQPHTSLAVTDVCIIIPGKGETPPHTFCKVDKNLNSSMWGSSVYLCYKKSLAKANTIAYKAGLLCRYPEEDYE---------------SFPLPESV---PMFCLPMGATIECWPAHTKHSLPVFSTFVLTGASGEKVYGAAIQFYEPHSEENLSERQRSQLGLPSSDLGPDGTRSVYSNKSICLLSHWPFFQSFRSFLTFLY------RYSISGPHALPIEKHISHFMQSVPFPSTQRPRILVQLSPHDSLILSQPVSSPLPL-------SGGSLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGVDSRYFDLYVPPADISCVDLDTNTISQKDDK-KALTWKILPRRA-----------CKYLLNTLNKLYQQLTEGGQLNREDIQMEHTVTDSELNGGKSLHTLELEIQEAFLRFMAAILRGYRSYLLPITQAPSEKTTDASSLFDLQGFLKSRDRSHQRFYSLMTKTQMFSRFIEECSFVSDKDASLAFFDECVDK---MDSERPEDTRLIELDESYRSEHTVYINPPE-----------------------LP-------------------------PLP-QGEEHPLHYSYSGFPVLNADLLEPLEGQNPPSAGMASRH--SSPASPTAIFRRSKQEIKSAQKMAK--TYSSMPQMWSKCLLRHCYGLWFICLPGLVGTCHSKV---------RALRTAYDVLRKMQEKKLQAPDEVCYRVLLQLCGQYSQPVLAVKVLFEMKKAGVQPNAITYGYYNKAVL--ESTWPSTTRGGYFLWGKLRNVVLGVLQFKQAGRKQQTP-HRDPQLSDGSDLDTVSHGSLDSANDSAERTSIDTDFTKMDSSDDGFSTGGQSDQGY 947 HSP 2 Score: 125.946 bits (315), Expect = 6.795e-25 Identity = 99/334 (29.64%), Postives = 152/334 (45.51%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKIN-TQS--------LAYTN---TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLYRCVTNSAAMEHMAPGIKSRIN----EALTGITNNY-LSDAIEALI-LIRIESGENANIMSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFR 5281
+I V M++CS C C VYD++IM GW+ NDS+L S CP+C + F P LN + P + G + TQS L T+ TV YLSP VL KELES+L EG+ A+ + + +H I++WNL+WY+ RL L ++L + + L++ S ++ V+ +QV+V + W+ P Y A + G+ E L G + SD + + +I++ E RS+YR+L L LG N +N D F+ Y + +L D PP + CR+ F+
Sbjct: 1355 TIEVLMSSCSLCKTCDCLVYDEEIMAGWTANDSNLNSTCPFCGTA-----------FLPFLNVEIKDLRPQTRGGHVCITQSRGQIVGNRLPSTSAPVTVPYLSPLVLWKELESLLVNEGDQAISSASIVDQHPIVFWNLVWYFRRLELQSNLPALI----------LASQHCSHGDQIPQSVSCEDSKQVLVRIMWDNLRLHQDKVQPCYVLWNTHCANSLVRSGLCEEGQLFTVELLQGFVRSIKKSDVYQPMSQIIQLLGPELGFKRQRSLYRDLLFLALVALGKNNINIDAFDREYKLAYDRLTPNLVKLTHNCDRPPGAGVMECRRTFK 1667
BLAST of C-myc promoter-binding protein vs. TrEMBL
Match: A0A3Q2VIB1 (DENN/MADD domain containing 4A OS=Haplochromis burtoni OX=8153 PE=4 SV=1) HSP 1 Score: 393.66 bits (1010), Expect = 6.378e-108 Identity = 304/974 (31.21%), Postives = 476/974 (48.87%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITD----IWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEK--QQILRK---NTGNVMDEFTILRKRENIGES-------IRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVS---MLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILE 2998
R+ +YF+++G +++ K + F ++ VK K P+ D+ +V + ++P GF V+ T S A+L G S ++FLCF+ GRDKPP+TD + FN K+K + +++ T +G AN+SSSSS +YI ++RAP + P +LAVTD+C+I+ K E P + +VD ++ S G ++ +CYKKS+ K N ++++ ++ P E LPE + FC+P GA +E W + P F TFVLT + ++YGAA+ FYE E+ L+ + + ++ + E +Y ++S+CLLS WP FQ+F L F+ R++ + P+S+PIE IS F+ V FP+ Q P IL+Q HD P+ LP +G + L+ L + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++G+DSR+FD + P + C+DL T +I ++ K L + + ++ CK + S K QQ++ N +V + T+ G+S I+E FLR + + R Y++YL+P++ + ++ +FDI GFLKS DR+ + Y + TQ++S FI E S+ ++ D LAFFD C+ M+ E A L++ D +SEHT ++PP +L PS GE++ L +Y+ +N+E LL E A +S+ I +R S S + +R +E+K A+ M K Y S W+ LL Y LWF+ LPG +G+ R L+ A +L M +L PDEVCYRVLL L Q L V L +K A + NA +YG N+ +LE
Sbjct: 7 RVADYFVVAGLTDSSKPLEEDLHF---DDAGPKSVKP-------KAPITDVAVVIRSLGEEVPPGFTCVETTPSGL-SAELNGASLRGPQIFLCFKRGRDKPPLTDLGVTVICFNWKEK---LKPGCHIVQTTPSGRPANISSSSSQRIYITYRRAPKSQPHTSLAVTDVCVIIPGKGETPPHTFCKVDKNLNSSMWGSSVYLCYKKSLAKANTIAYKAGLLCRYPKEDYE---------------SFPLPESV---PMFCLPMGAMIECWPAHTKHSLPVFSTFVLTGASGEKVYGAAIQFYEPYPEENLSERQRSQLGLPSSDLRPDETRNVYSNKSICLLSHWPFFQSFRSFLTFLY------RYSISGPHSLPIEKHISHFMQNVPFPSTQRPRILVQLSPHDSLMLSQPVSSPLPL-------SGGSLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGMDSRYFDLYVPPADITCVDLDTNTISQKDDK-KALTWKILPRRA-----------CKHLLNSLNKLYQQLIEGGHLNHEDVQMDHTVTDCELESGKSLHTLELEIQEAFLRFMAAILRGYRSYLLPITQAPSEKTTDASSLFDIQGFLKSRDRSHQRFYSLMTKTQMFSRFIEECSFVSDKDASLAFFDECVDK---MDSERPEDARLIELDESHRSEHTVYINPP---------------------ELPPPS----------QGEEHPLC-YSYSAFPVLNAE--------------------LLEPLEGASPSSAGIASRHSSPASPTAIFRRSKQEIKSAQRMAK--TYSSMPQMWSKCLLRHCYGLWFICLPGFVGNCHSKV---------RALRTAYDVLRKMQDKKLQAPDEVCYRVLLQLCGQYSQPVLAVRVLFEMKKAGVQPNAITYGYYNKAVLE 857 HSP 2 Score: 117.857 bits (294), Expect = 2.332e-22 Identity = 94/339 (27.73%), Postives = 142/339 (41.89%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTN------------------TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLYRCVTNSAAMEHMAPGIKSRIN----EALTGITNNYLSDAIEALI--LIRIESGENANIMSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
++ V M++CS C C VYD++IM GW+ NDS+L S CP+C + F P LN + P K + A TV YLSP VL KELES+L EG+ A+ + +H I++WNL+WY+ RL LP++L +L SQ ++ ++L + +QV+V + W+ P Y A + G+ E L G + + + +I++ E RS+YREL L LG N +N F+ Y + +L D PP + CR+ F
Sbjct: 1349 TVEVLMSSCSLCKTCDCLVYDEEIMAGWTANDSNLNSTCPFCGTA-----------FLPFLNVEIKDLRPHTPAQKRESSGGAGQAPASSSSSSSSCSSASAPVTVPYLSPLVLWKELESLLVNEGDQAISSPSVVDQHPIVFWNLVWYFRRLDLPSNL------------PALILGSQHCSHEDQMLSSEDS-KQVLVRIMWDNLKLHQDKVQPCYVLWNTHCANSLVRSGLCEEGQLFTVELLQGFVRSIKKSDVHQPMSQIIQLLGPELGFKRQRSLYRELLFLALVALGKNNINISAFDREYKLAYDRLTPNLVKLTHNCDRPPGAGVMECRRTF 1663
BLAST of C-myc promoter-binding protein vs. Ensembl Cavefish
Match: dennd4a (DENN domain containing 4A [Source:NCBI gene;Acc:103029279]) HSP 1 Score: 371.703 bits (953), Expect = 4.762e-104 Identity = 284/976 (29.10%), Postives = 455/976 (46.62%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNM------RDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILE 2998
R+ +YF+++G +++ K + EE V +D K P+ D+ +V + ++P G+ + T S A+L G S + ++FLC+R GRDKPP+TD+ + + K K C +I+ T +G AN+SSSSS +YI ++RA ++ +LAVTDIC+I+ K E P A+ +VD ++ S G ++ +CYKKS+ K N L+F+ ++ P E LPE + FC+P GA++E W + P F TFVLT + ++YGAA+ FYE E+ LT + + + + + + ++S+CLLS WP F F L F+ R++ + P+++PIE IS F+H V FP+ Q P IL+Q HD P+ LP +G L+ L + + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++GVDSR+FD + P + C+DL T +I P CK+L + Y LS + ++ + ++ D T ++ + + I+E FLR + + + Y++YL+P++ + ++ +FD+ GFLKS DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ + R ++ E L++ D +SEHT + PP+ L P P L S P ++ E + P ++ +H GS A++ +R +E+K A+ K Y S W+ LL + LWF+ LP + R L+ A +L M +L PDEVCYR+L+ L Q L V L +K A + NA +YG N+ +LE
Sbjct: 7 RVADYFVVAGLTDSSKPF---------EEDVTSDEGCQRTSAQPKAPITDVAVVIRSQGEEVPRGYTCIDCTPSGLP-AELNGGSLMGPQIFLCYRRGRDKPPLTDLGVLYEWREKLKPGCH-----IIQTTPSGRPANISSSSSQRIYITYRRAHESNSHASLAVTDICVIIPGKGETPPHAFCKVDKNLNSSMWGSSVYLCYKKSLAKTNTLAFKAGLLSRYPEEDYE---------------SFPLPESV---PLFCLPMGASIECWPSHTKYSLPVFSTFVLTGASGEKVYGAAIQFYESYPEERLTDRQRSQLGLHSSGLKNDDSMTVQTNKSICLLSHWPFFDAFRSFLTFLY------RYSISGPHTLPIEKHISHFMHKVPFPSSQRPRILVQLSPHDSLMLSQPVSSPLPL-------SGGRLSTLLLNLGPKNAVSLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGVDSRYFDLYEPPADISCVDLDTNTISHKEDRRALTWKILPRKACKHL-INTLSDLHQQLLESYQLSREEGQMEAAMSER----------DLGTGVKSLQTLELEIQEAFLRFMAAILKGYRSYLLPITQAPSEKATDASSLFDLQGFLKSRDRSHQKFYSLMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKLFGTEKERKVDSERPEDTRLIELDKSHRSEHTVYITPPE-----LPPVPDGEEPSMLYSYGGFPVLNAELCEPQEYA----------SVPKATSAPRHTSPGSPAAI----------------------------------FRRSKQEIKSAQRTAK--TYSSIPQMWSKCLLRHCHGLWFICLPTYVAACHSKV---------RALRTAYDVLRKMQDKKLQPPDEVCYRILMQLCGQYGQPVLAVRVLFEMKKAGVQPNAITYGYYNRAVLE 865 HSP 2 Score: 118.242 bits (295), Expect = 6.535e-26 Identity = 102/356 (28.65%), Postives = 161/356 (45.22%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTNT----------------------------------VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESL------SAASQSSRNK-YEILVNLTGFEQVVV---FLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALT-GITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
+I V M+ CS+C C+ VYD++IM GW+ +DS+L S CP+C SP F P LN V I Q G+ + Q L+ + T V YLSP VL KELES+L+ EG+ A+ + + H I++WNL+W++ RL LP++L + + L K S S+AS+ S+N +IL + Q + + W S +NP T+ + P + + +++ I N + + ++++ I RS+YR+L L LG N +N D F+ Y + +L + D PPS + CR+ F
Sbjct: 1406 AIEVRMSNCSRCNTCECLVYDEEIMAGWTADDSNLNSTCPFCG--------SP---FLPLLN--VDIRDLTGQ-GRTSCQDLSSSQTELNEALETQKEQSPSSESTGSPSSNTSRSTEPVTVPYLSPLVLWKELESLLENEGDKAISSAAIVDHHPIVFWNLVWFFRRLELPSNLPALI---LSSKHCSFDEQLLQSSASEDSKNVLVQILWDNPKLHQDPISPCYTLWNTYS-ANP-----TSFGPLLEEEPAVSLEVLQSVVRSIQKNDVYQPMSQ--ILQLLGTRLGFIRQRSLYRDLLFLSLVALGKNSINIDAFDREYKMAYDRLTPSQVKMTQNCDRPPSAGVMECRRTF 1736
BLAST of C-myc promoter-binding protein vs. Ensembl Cavefish
Match: dennd4a (DENN domain containing 4A [Source:NCBI gene;Acc:103029279]) HSP 1 Score: 370.163 bits (949), Expect = 1.396e-103 Identity = 283/970 (29.18%), Postives = 453/970 (46.70%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILE 2998
R+ +YF+++G +++ K + EE V +D K P+ D+ +V + ++P G+ + T S A+L G S + ++FLC+R GRDKPP+TD+ + + K K C +I+ T +G AN+SSSSS +YI ++RA ++ +LAVTDIC+I+ K E P A+ +VD ++ S G ++ +CYKKS+ K N L+F+ ++ P E LPE + FC+P GA++E W + P F TFVLT + ++YGAA+ FYE E+ LT + + + + + + ++S+CLLS WP F F L F+ R++ + P+++PIE IS F+H V FP+ Q P IL+Q HD P+ LP +G L+ L + + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++GVDSR+FD + P + C+DL T +I P CK+L + Y LS + ++ + ++ D T ++ + + I+E FLR + + + Y++YL+P++ + ++ +FD+ GFLKS DR+ + Y + TQ++ FI E S+ ++ D LAFFD C+ ++ E L++ D +SEHT + PP+ L P P L S P ++ E + P ++ +H GS A++ +R +E+K A+ K Y S W+ LL + LWF+ LP + R L+ A +L M +L PDEVCYR+L+ L Q L V L +K A + NA +YG N+ +LE
Sbjct: 7 RVADYFVVAGLTDSSKPF---------EEDVTSDEGCQRTSAQPKAPITDVAVVIRSQGEEVPRGYTCIDCTPSGLP-AELNGGSLMGPQIFLCYRRGRDKPPLTDLGVLYEWREKLKPGCH-----IIQTTPSGRPANISSSSSQRIYITYRRAHESNSHASLAVTDICVIIPGKGETPPHAFCKVDKNLNSSMWGSSVYLCYKKSLAKTNTLAFKAGLLSRYPEEDYE---------------SFPLPESV---PLFCLPMGASIECWPSHTKYSLPVFSTFVLTGASGEKVYGAAIQFYESYPEERLTDRQRSQLGLHSSGLKNDDSMTVQTNKSICLLSHWPFFDAFRSFLTFLY------RYSISGPHTLPIEKHISHFMHKVPFPSSQRPRILVQLSPHDSLMLSQPVSSPLPL-------SGGRLSTLLLNLGPKNAVSLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGVDSRYFDLYEPPADISCVDLDTNTISHKEDRRALTWKILPRKACKHL-INTLSDLHQQLLESYQLSREEGQMEAAMSER----------DLGTGVKSLQTLELEIQEAFLRFMAAILKGYRSYLLPITQAPSEKATDASSLFDLQGFLKSRDRSHQKFYSLMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDK---VDSERPEDTRLIELDKSHRSEHTVYITPPE-----LPPVPDGEEPSMLYSYGGFPVLNAELCEPQEYA----------SVPKATSAPRHTSPGSPAAI----------------------------------FRRSKQEIKSAQRTAK--TYSSIPQMWSKCLLRHCHGLWFICLPTYVAACHSKV---------RALRTAYDVLRKMQDKKLQPPDEVCYRILMQLCGQYGQPVLAVRVLFEMKKAGVQPNAITYGYYNRAVLE 856 HSP 2 Score: 118.242 bits (295), Expect = 5.843e-26 Identity = 102/356 (28.65%), Postives = 161/356 (45.22%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTNT----------------------------------VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESL------SAASQSSRNK-YEILVNLTGFEQVVV---FLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALT-GITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
+I V M+ CS+C C+ VYD++IM GW+ +DS+L S CP+C SP F P LN V I Q G+ + Q L+ + T V YLSP VL KELES+L+ EG+ A+ + + H I++WNL+W++ RL LP++L + + L K S S+AS+ S+N +IL + Q + + W S +NP T+ + P + + +++ I N + + ++++ I RS+YR+L L LG N +N D F+ Y + +L + D PPS + CR+ F
Sbjct: 1397 AIEVRMSNCSRCNTCECLVYDEEIMAGWTADDSNLNSTCPFCG--------SP---FLPLLN--VDIRDLTGQ-GRTSCQDLSSSQTELNEALETQKEQSPSSESTGSPSSNTSRSTEPVTVPYLSPLVLWKELESLLENEGDKAISSAAIVDHHPIVFWNLVWFFRRLELPSNLPALI---LSSKHCSFDEQLLQSSASEDSKNVLVQILWDNPKLHQDPISPCYTLWNTYS-ANP-----TSFGPLLEEEPAVSLEVLQSVVRSIQKNDVYQPMSQ--ILQLLGTRLGFIRQRSLYRDLLFLSLVALGKNSINIDAFDREYKMAYDRLTPSQVKMTQNCDRPPSAGVMECRRTF 1727
BLAST of C-myc promoter-binding protein vs. Ensembl Cavefish
Match: dennd4c (DENN domain containing 4C [Source:NCBI gene;Acc:103042516]) HSP 1 Score: 367.851 bits (943), Expect = 1.424e-102 Identity = 289/987 (29.28%), Postives = 468/987 (47.42%), Query Frame = 2
Query: 191 RICEYFLISGFSN--TRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTE--PIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQ-WDHD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSF----EKQQILRKNTGN--------VMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTK-----DIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNM----------RDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPR----KVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVS--MLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLIL--IHQLRPIRLHVSELLKHADL--NAFSYGLCNQIILE 2998
R+ +YF+++G ++ T DLS+ G K P+ D+ ++N ++ +P+GF ++ T + Q +G ELFLC++ G KPP++DI + K+ Q +I+ T G AN+ SS++S +++ F+R+P P ++LAVTDIC+I+ +K E P + +V+ ++ G ++ +CYKKS+ N ++++ +I+ P E P+ D FC+P GA +ESW+ N P P F TFVLT+ + ++YGAA+ FYE + L+ ++ + + + + ++ +CLLSRWP F+ F + L+F+ + + N +PIE IS F+H V FP+PQ P I++Q W H+ P+ LP +G ++ L++ L E L ++L E KILL S LTGIAEA++AMIFPF+W YIP L ++ +P P+++GVDSR+FD P V C+DL T +I + KY ++ + K CK+ + S + I+R+N + +FT + K + ++E FLR + + + Y++YL P++ + ++ D ++D+ GFLKS DR + Y + TQ++ FI E ++ ++ D GLAFFD CI+ + + E A LL+ D KSEHT + PP+P P K FP RL +L + P+ LS+ + ASL S+ P LL R ++ VK++ M KR + Q WA L S Y LWF+ LP AGL+ + R +Q AL +L M + + DEVCYRV++ L + + + + V +K A + NA +YG N+ +LE
Sbjct: 8 RVTDYFVVAGLTDKSTPLEQDLSETKSSGP----------------KAPITDLAVINKSAGETVPEGFTCIEVTTTGQPANLNHGSLKSPELFLCYKRGYGKPPLSDIGVL-YEGKDRLMQG-CEVIQATPYGRCANVNNSSATSQRIFVTFRRSPPVQPQNSLAVTDICVIITSKGETPPHTFLKVEKNLNCGMWGSSVFLCYKKSVSASNSIAYKAGLIFRYPEEDYESFPLSD--------------------SVPLFCLPMGAKIESWAPNTRYPLPVFSTFVLTSSSGEKVYGAAIQFYELYPTENLSEKQKIQLGLLTAVDKKPIPGRTVNTNKCICLLSRWPFFKAFKEFLMFLYRLS-----ADSVNPLPIEKHISHFMHNVPFPSPQRPRIMVQTWAHENIMLSQPVCTPLPL-------SGADYSTLLKNLGPENCATLLHFILLENKILLHSLRPDVLTGIAEAVVAMIFPFQWQCPYIPLCPLSLAGVLNAPCPFIVGVDSRYFDLHEPPPDVVCVDLDTNTIYLSDEK-KYSNWKNLPKKP-----------CKSLINSLVNLHHQLTIVRRNASENSAVEMTPIEADFTWVNKMAGLEMEVQEAFLRFMASILKGYRSYLKPITQAPSEKATAADSLYDLQGFLKSRDRAHQKFYSQLTKTQIFIRFIEECTFVSDKDTGLAFFDYCIEKLFPSDKGTDKGTKVEGEWSEDAKLLELDESQKSEHTVFIMPPEPPPDDGSQPPATYSYKSFP-RLRLELFDRPQELKPA----------LSN----------------RAAGASL----SSSPALLAK-----------RTKQEVKLAYKMAKRCYSNPPQ---------------WAKCLYSHCYSLWFICLP---------AGLRISHSKPRAMQQALNVLVKMRNTEVEVLDEVCYRVVMQLCGLWGMPVLAVRVLMEMKKAGVEGNAITYGYYNKAVLE 866 HSP 2 Score: 88.1965 bits (217), Expect = 8.923e-17 Identity = 71/233 (30.47%), Postives = 104/233 (44.64%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLY-RCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALI--LIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
+V YLSP VLRKELE++L+ EG+ + +FL +H I++WNL+WY+ RL LP+ L LT G L S +K V V L W+ + PLY R T +AP I L I + ++ + I L+R RSIYRE+ L LG + ++ + F+ Y + +L + + D PPS +C K F
Sbjct: 1719 SVPYLSPLVLRKELETLLENEGDQVIYTQKFLSQHPIIFWNLVWYFRRLDLPSILPGLILTSEHCNNGVQLPQTSLPQDSKL-----------VYVQLLWDNVNLHQEPTEPLYQRWRTFLQMKGSLAPTDHQEIRTLLNSIVRSIQTNDVYGPINLLLREIKRHPELKRQRSIYREILFLSLVALGRENIDVEAFDREYRVAFDELSPEQLKALSPIDRPPSNNVQWCVKCF 1940 HSP 3 Score: 58.9214 bits (141), Expect = 6.574e-8 Identity = 21/45 (46.67%), Postives = 34/45 (75.56%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS 4483
++ V M++CSQC +C+ VYD++IM GW+ +DS+L + CP+C S
Sbjct: 1519 ALEVLMSSCSQCRSCEALVYDEEIMAGWTADDSNLNTTCPFCQTS 1563
BLAST of C-myc promoter-binding protein vs. Ensembl Cavefish
Match: dennd4c (DENN domain containing 4C [Source:NCBI gene;Acc:103042516]) HSP 1 Score: 367.851 bits (943), Expect = 1.546e-102 Identity = 289/987 (29.28%), Postives = 468/987 (47.42%), Query Frame = 2
Query: 191 RICEYFLISGFSN--TRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTE--PIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQ-WDHD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSF----EKQQILRKNTGN--------VMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTK-----DIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNM----------RDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPR----KVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVS--MLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLIL--IHQLRPIRLHVSELLKHADL--NAFSYGLCNQIILE 2998
R+ +YF+++G ++ T DLS+ G K P+ D+ ++N ++ +P+GF ++ T + Q +G ELFLC++ G KPP++DI + K+ Q +I+ T G AN+ SS++S +++ F+R+P P ++LAVTDIC+I+ +K E P + +V+ ++ G ++ +CYKKS+ N ++++ +I+ P E P+ D FC+P GA +ESW+ N P P F TFVLT+ + ++YGAA+ FYE + L+ ++ + + + + ++ +CLLSRWP F+ F + L+F+ + + N +PIE IS F+H V FP+PQ P I++Q W H+ P+ LP +G ++ L++ L E L ++L E KILL S LTGIAEA++AMIFPF+W YIP L ++ +P P+++GVDSR+FD P V C+DL T +I + KY ++ + K CK+ + S + I+R+N + +FT + K + ++E FLR + + + Y++YL P++ + ++ D ++D+ GFLKS DR + Y + TQ++ FI E ++ ++ D GLAFFD CI+ + + E A LL+ D KSEHT + PP+P P K FP RL +L + P+ LS+ + ASLS+ P LL R ++ VK++ M KR + Q WA L S Y LWF+ LP AGL+ + R +Q AL +L M + + DEVCYRV++ L + + + + V +K A + NA +YG N+ +LE
Sbjct: 8 RVTDYFVVAGLTDKSTPLEQDLSETKSSGP----------------KAPITDLAVINKSAGETVPEGFTCIEVTTTGQPANLNHGSLKSPELFLCYKRGYGKPPLSDIGVL-YEGKDRLMQG-CEVIQATPYGRCANVNNSSATSQRIFVTFRRSPPVQPQNSLAVTDICVIITSKGETPPHTFLKVEKNLNCGMWGSSVFLCYKKSVSASNSIAYKAGLIFRYPEEDYESFPLSD--------------------SVPLFCLPMGAKIESWAPNTRYPLPVFSTFVLTSSSGEKVYGAAIQFYELYPTENLSEKQKIQLGLLTAVDKKPIPGRTVNTNKCICLLSRWPFFKAFKEFLMFLYRLS-----ADSVNPLPIEKHISHFMHNVPFPSPQRPRIMVQTWAHENIMLSQPVCTPLPL-------SGADYSTLLKNLGPENCATLLHFILLENKILLHSLRPDVLTGIAEAVVAMIFPFQWQCPYIPLCPLSLAGVLNAPCPFIVGVDSRYFDLHEPPPDVVCVDLDTNTIYLSDEK-KYSNWKNLPKKP-----------CKSLINSLVNLHHQLTIVRRNASENSAVEMTPIEADFTWVNKMAGLEMEVQEAFLRFMASILKGYRSYLKPITQAPSEKATAADSLYDLQGFLKSRDRAHQKFYSQLTKTQIFIRFIEECTFVSDKDTGLAFFDYCIEKLFPSDKGTDKGTKVEGEWSEDAKLLELDESQKSEHTVFIMPPEPPPDDGSQPPATYSYKSFP-RLRLELFDRPQELKPA----------LSN----------------RAAGASLSSS----PALLAK-----------RTKQEVKLAYKMAKRCYSNPPQ---------------WAKCLYSHCYSLWFICLP---------AGLRISHSKPRAMQQALNVLVKMRNTEVEVLDEVCYRVVMQLCGLWGMPVLAVRVLMEMKKAGVEGNAITYGYYNKAVLE 866 HSP 2 Score: 59.3066 bits (142), Expect = 5.682e-8 Identity = 58/212 (27.36%), Postives = 89/212 (41.98%), Query Frame = 2
Query: 4676 IALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLY-RCVTNSAAMEHMAPG----IKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
+ + +FL +H I++WNL+WY+ RL LP+ L LT G L S +K V V L W+ + PLY R T +AP I++ +N + I N + I L+L I+ RSIYRE+ L LG + ++ + F+ Y + +L + + D PPS +C K F
Sbjct: 1705 VVIYTQKFLSQHPIIFWNLVWYFRRLDLPSILPGLILTSEHCNNGVQLPQTSLPQDSKL-----------VYVQLLWDNVNLHQEPTEPLYQRWRTFLQMKGSLAPTDHQEIRTLLNSIVRSIQTNDVYGPIN-LLLREIKRHPELK-RQRSIYREILFLSLVALGRENIDVEAFDREYRVAFDELSPEQLKALSPIDRPPSNNVQWCVKCF 1903 HSP 3 Score: 58.9214 bits (141), Expect = 6.895e-8 Identity = 21/45 (46.67%), Postives = 34/45 (75.56%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS 4483
++ V M++CSQC +C+ VYD++IM GW+ +DS+L + CP+C S
Sbjct: 1519 ALEVLMSSCSQCRSCEALVYDEEIMAGWTADDSNLNTTCPFCQTS 1563
BLAST of C-myc promoter-binding protein vs. Ensembl Cavefish
Match: dennd4c (DENN domain containing 4C [Source:NCBI gene;Acc:103042516]) HSP 1 Score: 356.681 bits (914), Expect = 2.853e-99 Identity = 285/982 (29.02%), Postives = 466/982 (47.45%), Query Frame = 2
Query: 191 RICEYFLISGFSN--TRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTE--PIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSF----EKQQILRKNTGN--------VMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTK-----DIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNA---------ASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLIL--IHQLRPIRLHVSELLKHADL--NAFSYGLCNQIILEQEQQWSQK 3022
R+ +YF+++G ++ T DLS+ G K P+ D+ ++N ++ +P+GF ++ T + Q +G ELFLC++ G KPP++DI + K+ Q +I+ T G AN+ SS++S +++ F+R+P P ++LAVTDIC+I+ +K E P + +V+ ++ G ++ +CYKKS+ N ++++ +I+ P E P+ D FC+P GA +ESW+ N P P F TFVLT+ + ++YGAA+ FYE + L+ ++ + + + + ++ +CLLSRWP F+ F + L+F+ + + N +PIE IS F+H V FP+PQ P I++Q + + L + +G ++ L++ L E L ++L E KILL S LTGIAEA++AMIFPF+W YIP L ++ +P P+++GVDSR+FD P V C+DL T +I + KY ++ + K CK+ + S + I+R+N + +FT + K + ++E FLR + + + Y++YL P++ + ++ D ++D+ GFLKS DR + Y + TQ++ FI E ++ ++ D GLAFFD CI+ + + T A LL+ D KSEHT + PP+P S K FP RL +L + P+ LS+ + ASLS+ P LL R ++ VK+ A M K Y + WA L S Y LWF+ LP AGL+ + R +Q AL +L M + + DEVCYRV++ L + + + + V +K A + NA +YG N++ + E W +
Sbjct: 8 RVTDYFVVAGLTDKSTPLEQDLSETKSSGP----------------KAPITDLAVINKSAGETVPEGFTCIEVTTTGQPANLNHGSLKSPELFLCYKRGYGKPPLSDIGVL-YEGKDRLMQG-CEVIQATPYGRCANVNNSSATSQRIFVTFRRSPPVQPQNSLAVTDICVIITSKGETPPHTFLKVEKNLNCGMWGSSVFLCYKKSVSASNSIAYKAGLIFRYPEEDYESFPLSD--------------------SVPLFCLPMGAKIESWAPNTRYPLPVFSTFVLTSSSGEKVYGAAIQFYELYPTENLSEKQKIQLGLLTAVDKKPIPGRTVNTNKCICLLSRWPFFKAFKEFLMFLYRLS-----ADSVNPLPIEKHISHFMHNVPFPSPQRPRIMVQ------VFLLLHSSQFLSQHSGADYSTLLKNLGPENCATLLHFILLENKILLHSLRPDVLTGIAEAVVAMIFPFQWQCPYIPLCPLSLAGVLNAPCPFIVGVDSRYFDLHEPPPDVVCVDLDTNTIYLSDEK-KYSNWKNLPKKP-----------CKSLINSLVNLHHQLTIVRRNASENSAVEMTPIEADFTWVNKMAGLEMEVQEAFLRFMASILKGYRSYLKPITQAPSEKATAADSLYDLQGFLKSRDRAHQKFYSQLTKTQIFIRFIEECTFVSDKDTGLAFFDYCIEKLFPSDKGTDKGTKVREWSEDAKLLELDESQKSEHTVFIMPPEPPPDD--GSHYKSFP-RLRLELFDRPQELKPA----------LSN----------------RAAGASLSSS----PALLAK-----------RTKQEVKL------------AYKMAKRC-YSNPPQWAKCLYSHCYSLWFICLP---------AGLRISHSKPRAMQQALNVLVKMRNTEVEVLDEVCYRVVMQLCGLWGMPVLAVRVLMEMKKAGVEGNAITYGYYNKVAV-LESPWPSR 861 HSP 2 Score: 89.7373 bits (221), Expect = 3.234e-17 Identity = 72/235 (30.64%), Postives = 109/235 (46.38%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLYRCVTNSAAME-HMAPG----IKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
+V YLSP VLRKELE++L+ EG+ + +FL +H I++WNL+WY+ RL LP+ L LT G L S +K V V L W+ + PLY+ M+ +AP I++ +N + I N + I L+L I+ RSIYRE+ L LG + ++ + F+ Y + +L + + D PPS +C K F
Sbjct: 1514 SVPYLSPLVLRKELETLLENEGDQVIYTQKFLSQHPIIFWNLVWYFRRLDLPSILPGLILTSEHCNNGVQLPQTSLPQDSKL-----------VYVQLLWDNVNLHQEPTEPLYQRWRTFLQMKGSLAPTDHQEIRTLLNSIVRSIQTNDVYGPIN-LLLREIKRHPELK-RQRSIYREILFLSLVALGRENIDVEAFDREYRVAFDELSPEQLKALSPIDRPPSNNVQWCVKCF 1735 HSP 3 Score: 55.4546 bits (132), Expect = 7.615e-7 Identity = 20/38 (52.63%), Postives = 29/38 (76.32%), Query Frame = 2
Query: 4370 TCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS 4483
TCSQC +C+ VYD++IM GW+ +DS+L + CP+C S
Sbjct: 1368 TCSQCRSCEALVYDEEIMAGWTADDSNLNTTCPFCQTS 1405
BLAST of C-myc promoter-binding protein vs. Ensembl Sea Lamprey
Match: dennd4a (DENN/MADD domain containing 4A [Source:ZFIN;Acc:ZDB-GENE-060503-285]) HSP 1 Score: 328.946 bits (842), Expect = 1.390e-91 Identity = 224/726 (30.85%), Postives = 371/726 (51.10%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYF--RSKNETQT--SEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHD------HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRK--NTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRD---------MNDETVNAASLLQTDSVIKSEHT 2287
R+ +YF+++G + K + F +G + ++P+ D+ +V + + P G+ ++ T +N ADL +G + +L+LC+R GRDKPP+TD+ + K Q T I T G AN+++S+ + +Y+ ++RA ++A + LAVTDICII+A+K E P + +V+ ++ G ++ +CYKKS+V+ N ++++ + P E LPE + FC+P GA +E W P P F TF+LT+V+ +++YGAAV FYE + L+ ++ RSK + + P+ + ++ +CLLSRWP F F + LLF+ + F+ P +++PIE IS F+ V FP+ Q P IL+Q + PI LP G +F L++ L E L ++ LTE KIL+ S + LT AEAL AMIFPF W YIP L ++ +P P+++GVDSR+FD + P V +DL T +I E K L++ + K + L+N ++V+ + + +G +F +++ + I+E FLR + + + Y+ YL P++ + ++ +FD+ GFLKS DR Y + TQ++ FI E S+ T+ D LAFFD C++ + ++ E + L++ D +SEHT
Sbjct: 8 RVADYFVVAGLTEESKPLEEDMAFAEGRQKA----------VRRRDPITDVAVVCRSQGEEPPQGYTCIEATPTNLD-ADLNHGSLSSPQLYLCYRRGRDKPPLTDLGVL-YEWKERLMQGCET-IRTTPYGRPANVNNSAQH-IYVTYRRAHESASQNALAVTDICIIVASKGETPPHTFCKVNKNLNSGMWGASVFLCYKKSVVRANSIAYKAGQLSRYPTEDYE---------------TFPLPEPV---PMFCLPMGAVIECWPPKTKCPAPIFSTFILTSVSGDKVYGAAVQFYEPYPAERLSEKQGVQLGLRSKVDRRPLPGPPFSVNANKCICLLSRWPFFDAFRKFLLFVY----RLSFSGP-HALPIEKHISHFMFHVPFPSSQRPRILVQATANDSLVLSQPIASPLPI-------RGASFCTLLQNLGPENAATLLLFALTENKILIHSLRPAVLTSAAEALNAMIFPFHWQCPYIPLCPLSLADMLSAPCPFIVGVDSRYFDLYEPPPDVVSVDLDTNTISQTEER-KSLNWRLLPKKPCKNLMNT-LTNLHQQIVAMNHRSMEDPVLESGIFDLDFKRRARQQQLEMEIQEAFLRFMASILKGYRTYLRPITQAPSEKATDARSLFDLQGFLKSRDRAYNKFYSQMMRTQMFIRFIEECSFVTDKDASLAFFDDCVEKVESDKGAERGFMVDVEKADDVRLIELDESYRSEHT 687 HSP 2 Score: 59.6918 bits (143), Expect = 7.726e-9 Identity = 44/136 (32.35%), Postives = 66/136 (48.53%), Query Frame = 2
Query: 2609 SMLKRPFEELKQARLMGKEAKYGSSYA--WAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADL----NAFSYGLCNQIILE 2998
++ +R +E+K A+ K+A+ S+ WA LL Y LWF+ LP + + T R L+ A +L M ++L PDEVCYRVL+ L L V L + + NA +YG N+ +LE
Sbjct: 746 ALARRTKQEIKSAQ---KQARKCSAMPQMWAKCLLGHCYSLWFICLPSYV---------RVTHPKSRALRTAYDVLLRMQAHKLEPPDEVCYRVLMQLCGLYGHPVLAVKVLFEMKKMGVQPNAITYGFYNKAVLE 869 HSP 3 Score: 51.9878 bits (123), Expect = 1.623e-6 Identity = 18/51 (35.29%), Postives = 34/51 (66.67%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSN 4501
++ V +++CS+C C+ VYD+++M GW +DS+L + CP+C + + N
Sbjct: 1531 AMEVLISSCSRCRACESLVYDEEVMAGWMADDSNLNTTCPFCGSTLKAFLN 1581
BLAST of C-myc promoter-binding protein vs. Ensembl Sea Lamprey
Match: dennd4a (DENN/MADD domain containing 4A [Source:ZFIN;Acc:ZDB-GENE-060503-285]) HSP 1 Score: 308.531 bits (789), Expect = 5.736e-85 Identity = 217/726 (29.89%), Postives = 363/726 (50.00%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANL--XXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSI------------KPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKR--ENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHT 2287
R+ +YF+++G ++T + + EE+ +D K P+ D+ ++ + ++P GF +++T ADL +G +++LC+R GRDKPP+TD+ + + + + C L+E T G AN+ SS+ S + + F+RA D + LAVTDIC+I+ANK E P + +VD ++ G + +CYKKS+VK N ++++ +I S P+ D LPE + FC+P GAT+E W N P P F TFVLT + ++YGAA+ F+E + LT + S + + + S+S+CLLS WP F+ F++ LLF+ + + PN IPIE IS F+H FP+PQ P IL+Q + + P + +G +F L+ L E ++ L L E KIL+ S + T +AEAL+++IFPF W Y+P L ++ +P P+++GVDSR+F+ + P + +DL T +I P+ CK L GL+ ++ + + ++ + + + +R R + I+E FLR + + + Y++YL P++ + ++ +FD+ GFLKS DR+ Y + TQ++ FI E S+A + + LAFFD C++ + + E L++ D ++ EHT
Sbjct: 8 RVADYFVLAGLTDTSRPLE--------EEMSQSDGG--PRTARPKAPITDVAVIVKSHGEEVPQGFTCIESTPLGLP-ADLNHGSLKSPQIYLCYRRGRDKPPLTDLGVLYEWKDRLRPGCE-----LVETTPYGRCANVNNSSAVSQRILLTFRRATDQNAQNTLAVTDICVIVANKGESPPHTFCKVDRNLNSGMWGSDVYLCYKKSLVKSNAIAYKAGLI------SRYPVGDY---------ESFQLPESV---PLFCLPLGATIECWQANTKYPMPIFSTFVLTGSSAEKVYGAAIQFFEAYPGERLTDRQKTQLGMLSAVDHKPIAGKVAHASKSICLLSHWPFFEAFHKFLLFLYRLS-----VSGPNLIPIEKHISHFMHNTPFPSPQRPRILVQLSPHDSLTLSQPASSPLPL-SGASFSMLLVNLGPEHLLALLHAALMENKILIHSLRPAIQTSVAEALVSVIFPFHWQCPYVPLCPLALATVLNAPFPFIVGVDSRYFELYDPPLDIVSVDLDTNTIFQNEEKKGTSWKALPKKPCKILQ--------------AGLTRLYQELQRNYNETLQQQRKDDSLTDVAGVRCRSAHTLEVEIQEAFLRFMASILKGYRSYLRPITQAPSEKATDASSLFDLQGFLKSRDRSYHKFYTQLTKTQMFIRFIEECSFAGDKNASLAFFDDCVEKVDVEHGEETR---LVELDESLRGEHT 676 HSP 2 Score: 119.013 bits (297), Expect = 7.916e-27 Identity = 105/380 (27.63%), Postives = 175/380 (46.05%), Query Frame = 2
Query: 4229 DKVTGSLGAIRLPTGKYWPDSQIDGDSPAA---AAAPCIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDS-----------NRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTNTVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSS--RNKYEILVNL--------TGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQ-VNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQL 5293
D+ GS P+ + P +D P + A++ I + V +++CSQC C+ VYD+ IM GW+ +DS+L + CP+CN + R+ S T + + H + +I Q + +V YLSP VLRKELE +++ EG+ + L +H IL+WNLLWY+ RL LP+HL + L + R G S + SQS R +LV+ EQ +++ W+ ++P + N + +++ R+ + + G N+ S + +L RS+YREL +G + V+ +VF+ Y +++ + +D PPS CR+ F L+L
Sbjct: 1337 DEACGSCRERSFPSARNIPVLTVDRAEPGSPHYASSCSISQRPDVEVRISSCSQCHTCEGLVYDEQIMAGWTADDSNLNTACPFCNSTFVPCLSIEISDRRSCGKYVSNSVTCFGEQMTFYEHDANFSNEIQLQ--PESTSVPYLSPMVLRKELERLMEDEGDRTVCSVALLQQHPILFWNLLWYFQRLQLPSHLPALLLL--SRLGHSGTQVSQSGGPREGRRVLVHTLWDNRKLHQDLEQ-PLYVLWDTLGNASP-GKAGQNPGKL-NLSRNDLERMEKHIKG--NDVYSPICQ--LLDAWSHRNRNLRRHRSLYRELLFFSLVSMGAENVDINVFDQEYRREHERITTN-GGRLLNYDLPPSAAASSCRQAFGELRL 1704 HSP 3 Score: 59.3066 bits (142), Expect = 1.162e-8 Identity = 43/108 (39.81%), Postives = 59/108 (54.63%), Query Frame = 2
Query: 2690 WAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQL-RPIRLHVSEL--LKHADL--NAFSYGLCNQIILE 2998
WA LL + Y LWF+ LP A + + L R+L+ A +L M +RL PDEVCYRVL+ + Q RP+ L V L +K A + NA +YG N+ +LE
Sbjct: 765 WAMCLLGNCYSLWFICLPAY-------AKARHSKL--RVLETAYSVLLRMQEHRLECPDEVCYRVLMQVCGQYGRPV-LAVKVLFEMKKAGIHPNAITYGYYNKALLE 862
BLAST of C-myc promoter-binding protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010382.1 (pep scaffold:Pmarinus_7.0:GL482471:369374:413667:1 gene:ENSPMAG00000009395.1 transcript:ENSPMAT00000010382.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 94.7449 bits (234), Expect = 1.969e-19 Identity = 73/254 (28.74%), Postives = 114/254 (44.88%), Query Frame = 2
Query: 953 FCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVL--LFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLP-TDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFF 1705
FC P G W + PSF VLT++N R Y A + F E E + E ++T +P +++ +SL L+SR + F L L+ D + +P+ET + L V PT L IQ P D L TG + L R L + ++ LF +TE K+L S+ L+ A++A++FP K+S YIP L + + ++ +P+P++IGV S F +
Sbjct: 30 FCQPSG-----WKTSTERVPPSFFVVVLTDINSERHYCACLTFQEPFLEPNDSDGEEEEQEEVDDTGLVKPAQVFAPKSLVLVSRRDCTEIFRNCLGLLYTAHTDSLR--------VPLETLVGNLLSCVV-PTAGGAQKLFSLGAGDRQVIQAPLNDTLPI--TGSSVAILFRQLGIRHVLNLFCAAVTEHKVLFHSSSYQRLSDACRAMLALMFPLKYSYPYIPILPAQLLEVLSTPTPFIIGVHSMFINHL 267
BLAST of C-myc promoter-binding protein vs. Ensembl Sea Lamprey
Match: sbf1 (SET binding factor 1 [Source:ZFIN;Acc:ZDB-GENE-040718-139]) HSP 1 Score: 89.3521 bits (220), Expect = 8.069e-18 Identity = 76/278 (27.34%), Postives = 122/278 (43.88%), Query Frame = 2
Query: 953 FCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQT-----SEPYKIYCSRSLCLLSRWPLFQTFNQVL--LFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPE 1765
FC P G W L+ +P+F VLT++ +R + A + FYE D ++ + +E+ S + + +SL L+SR + + Q L ++ I D+ + + +E + L T PT + IQ P TG + L R L + ++ LF +LTE KIL S+ LT AL+A+ FP K+S YIP L + ++ +P+P++IGV S F F+ V DL ++ PE
Sbjct: 48 FCQPSG-----WKLSNEWKQPTFFVAVLTDIESDRHFCACLTFYEPEDSTYEIVTGHSFQQKDSESDGEGEDESHHMQRFAPKSLVLVSRLDYTEIYRQSLGLIYAIHVDDLK--------VTLENVVGNLL-TCMIPTSGGAQKVFSLGAGDRQVIQ-PALNNEIPVTGSSVILLFRQLGINNVLHLFCAVLTEHKILFHSSSYQRLTEACRALVALTFPLKYSYTYIPILPGSLLEVLSTPTPFIIGVHSTFRSEFQELLDVIIADLDGGTVMIPE 310
BLAST of C-myc promoter-binding protein vs. Ensembl Sea Lamprey
Match: dennd5a (DENN/MADD domain containing 5A [Source:ZFIN;Acc:ZDB-GENE-071211-1]) HSP 1 Score: 77.7962 bits (190), Expect = 2.370e-14 Identity = 73/312 (23.40%), Postives = 130/312 (41.67%), Query Frame = 2
Query: 953 FCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQT---------------------------------SEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNP-PNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPT-DALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIG--VDSRFF-DFFRLPEGVG--CIDLITKSIKPPEN 1768
CMP G + + + R P F +F++T + +R YG A+ F+EE+ + + + Q S ++ S+ +CL++ P Q + L + T+P P +P+E+++ L+ V P P ++ + P+ Q P L F + +L +E ++QLF L E +ILL S L +AE ++ ++FPF W VY+P L +H + +P PYL+G +D + LP+ +D+ +S++ PE
Sbjct: 46 LCMPRGLSFRTQADRRD---PEFHSFLITREDGSRTYGFALTFFEEVRSEPIREAMQTLYAMHRAEQAGLAESTSSDFGDTDSATGLSSSLLRMRHSASYDSSRDTLFTSKCICLIAPMPFVQACRKALTQL-----HTAVTSPQPPPLPLESYVYNLLYEVPLP-PLGRSLRFSSVYMPPVVCQRPGPHELPLFDYC--LREVFELLGLENVVQLFTCALLEHQILLLSRDYQRLMVVAEGIMVLLFPFSWQHVYVPILPASLLHFLDAPVPYLMGLQIDGEMGRNGLELPQEASLCLVDVDNRSLELPEE 346
BLAST of C-myc promoter-binding protein vs. Ensembl Nematostella
Match: EDO46064 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR72]) HSP 1 Score: 278.485 bits (711), Expect = 4.928e-78 Identity = 209/730 (28.63%), Postives = 354/730 (48.49%), Query Frame = 2
Query: 188 RRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADL-YGKSAVDELFLCFRYGRDKPPITDIWA-FNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGI-QLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIK-----PPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGE--------SIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTD--SVIKSEHTKVLDPPD 2308
+R+ +YF+++G K D+ ++ GEE+ + EP+ D+ ++ + + P G+ ++ + + ADL +G FLC++ G DKPP+TDI + K + D +I T G AN+++S + YI ++RA +LAVT+IC+I+A+K E P A+ ++ ++ + +G + +CY+KS+ + +++ +I+ P E LPE + FC+P GA +E W P P F TFVLT + ++YGAAV F+E++ E+++T E + +++ + + ++ +C+LS WP F+ F + L + R + IPIE +I+ + V FP+PQ P IL++ P I QL L +G ++ ++R L + + LF +LTE KIL+ S + LT +AEAL ++FPF W YIP + ++ +P P++IG+DSR+FD + P+ V +DL T I P + K L Y ++ Q+ K D F +L NI SI+E FLR + ++ + Y +YL P++ T++ +FD+ GFLKS + + +Q + TQ++S FI +RS+ T D LAFFD C ++ + L++ D S + T V+ PPD
Sbjct: 8 QRVADYFVVAGLGENSKPTDIDKL---GEEVSSV-----------LEPITDLAVIFKSLGERPPPGYEWIEKSPAG-FPADLNHGSIRQPSCFLCYKRGSDKPPLTDIGVLYEGKDRLMSGCD---IITNTPYGRPANVNNSGGSRTYITYRRASQQMAHTSLAVTEICVIVASKGEKPPHAFCIIERNLNKGMVGSDVYLCYRKSLSRAKCITYHADILSRFPEKDYE---------------GFPLPEAV---PMFCLPLGAIIECWPEKCQHPLPLFSTFVLTGASGQKIYGAAVTFFEQLPEEKVTEEMRVALKLNDQSMVA-----HTNKCICILSHWPFFEAFKKFL------SQLYRISVSAQQIPIERYIANMMLDVPFPSPQRPRILIEMTRYEPFEISQLYHSPLPV--SGASYSAMLRHLGPDNCLLLFYLILTEHKILIHSLRPALLTSVAEALTNVLFPFTWQCPYIPLCPVALNDVLCAPCPFIIGIDSRYFDQYDPPDDVTSVDLDTIMISQALEIKPSASWKSLPKKPGKVLRDRLMELY-----------YQLYQLYHKEKEGEYD-FCVLLYVFNIQRELKMTCIISIQEAFLRFMAVILKGYGSYLKPITSRPTQETCDVTSLFDLQGFLKSRPSSHQKFFQQLTITQMFSRFIEQRSFVTSQDALLAFFDEC-------QEKLDSPKPLIEVDESSTRGGQRTYVVTPPD 669 HSP 2 Score: 53.5286 bits (127), Expect = 8.993e-7 Identity = 42/131 (32.06%), Postives = 59/131 (45.04%), Query Frame = 2
Query: 2618 KRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILE 2998
+R +E Q+ L K+ GS WA LL+ Y LWF+ LP + A + L A +L M + L DEVC+RV + L Q L V L +K L NA +YG N+ ++E
Sbjct: 715 RRTKQERAQSILSAKKNA-GSPVQWARCLLAECYSLWFIHLPAYVKCHHNKA---------KALHFAYEILCKMPTKGVKLTDEVCFRVFMQLCGQFGHPALAVKVLFEMKTQGLTPNAVTYGYYNRAVME 835
BLAST of C-myc promoter-binding protein vs. Ensembl Nematostella
Match: EDO46065 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR74]) HSP 1 Score: 91.2781 bits (225), Expect = 3.780e-20 Identity = 61/240 (25.42%), Postives = 121/240 (50.42%), Query Frame = 2
Query: 4607 TVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSF-LTIWLKRKGESLSAASQSSRNKYEILVNLT------GFEQVVVFLFWEFASTSN-PLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCL-ITAVLGNQVNYDVFNFTYNSPWQQL--KRKYQAYVKTHDNPPSEQTLFCRKFFRPLQL 5293
TV Y+SP VLRKELE++LD +G+ AL + +++ I++WN++W + RL LP+HL L + + + + + +++L++ + + V +++ W ++N PL + ++ + + + + I N + I L+ E ++ RS+YREL L +TA ++ + ++ Y ++++ ++Y + T D PPS + +FCR+ F P L
Sbjct: 4 TVAYVSPLVLRKELENMLDNDGDAALQNPDIVHQKDIIFWNMMWIFKRLELPSHLPELILPNYPGDRNDKFDVCAIP--DLFQVLMSTSWDSDRQDCDFVPMYVLWNSPMSTNFPLNHFIR----IQRLQASRRKLLRSVVAHIQINDVDSPITILL---DERNRQSHSSYRSVYRELLFLSLTACGSEHIDVEAYDREYRKSYKRIVENKEYVDKLCTEDKPPSARVVFCRRLFTPPAL 234
BLAST of C-myc promoter-binding protein vs. Ensembl Nematostella
Match: EDO30806 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZQ4]) HSP 1 Score: 59.3066 bits (142), Expect = 7.887e-9 Identity = 52/175 (29.71%), Postives = 79/175 (45.14%), Query Frame = 2
Query: 1295 IPIETFISQFLHTVAFPTPQ--------APNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDF---FRLP-EGVGCIDLITKSIKPPENNCKYL 1783
+P+E++I L+ V P P +I Q P +LP L + E F L VE +++LF +L E +ILL S +AE ++ +IFPF W VY+P L H + +P P+++G+ DF +LP E C+ I +NCK L
Sbjct: 221 LPLESYIYNLLYEVPLPPPGRTMRFNCVKESITCQ----RPGPNELP---LFDYSLKEMF----SWLGVENVVELFTCVLLEHQILLLSNSFHRFMLVAEGVVTLIFPFIWQHVYVPILPAALQHFLDAPVPFIMGLYCASEDFKANLQLPSEASLCLVDI--------DNCKVL 376
BLAST of C-myc promoter-binding protein vs. Ensembl Nematostella
Match: EDO42638 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0T9]) HSP 1 Score: 53.9138 bits (128), Expect = 9.170e-8 Identity = 43/167 (25.75%), Postives = 81/167 (48.50%), Query Frame = 2
Query: 1190 LCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFP-TPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDS 1687
LC+LS P F+ F +L I D + T+ S+ + F+ + L P T AP Q+ + P ++LPT +R N ++ + +I +F+ M E++I++TS + LT +++++P W +++P + + +P P+L+GV S
Sbjct: 29 LCILSYLPWFEIFYDLLNKI--SDLIRSSTDEVVSL-LNAFVKEPLPKPGTPFTITAPGTTKQYTYTSPDPMKLPTIPANR-----NLTDYYAAVEPQNMITMFISMFFERRIIITSKKLNVLTACCYGAMSLLYPMHWQHMFVPIVPPHLLDYCCAPMPFLVGVHS 187
BLAST of C-myc promoter-binding protein vs. Ensembl Medaka
Match: dennd4a (DENN domain containing 4A [Source:NCBI gene;Acc:101171828]) HSP 1 Score: 381.719 bits (979), Expect = 2.224e-107 Identity = 321/1083 (29.64%), Postives = 489/1083 (45.15%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFT-NPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRK----NTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFS---QTKDI--MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNM----RDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFL---LVTPESAMNASSNIRNRR----SVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILEQEQQWSQ----------KLSNLSTST---KQPKCDSDNPDKPIAVEKEGKDEKDCDS-GRETLASANIAPEEAQ--------DSSDSGCNLIMKSDNNY 3229
R+ +YF+++G ++ K + F ++ VK K P+ D+ +V + ++P GF V+ T + A+L G S ++FLCF+ GRDKPP+TD+ + + K K C +++ T +G AN+SSSSS +YI ++R+P + P +LAVTD+C+I+ K E P + +VD ++ S G +I +CYKKS+ K N ++++ ++ P E LPE + FC+P GA +E W + P F TFVLT + ++YGAA+ FYE E+ LT + + + ++ E Y ++S+CLLS WP F +F L F+ R++ + P+++PIE +S F+ V FP+ Q P IL+Q HD P+ LP +G + L+ L + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++G+DSR+FD + P + C+DL T +I P CKYL LS +++ E Q+ R N DE + + I+E FLR + + R Y++YL P++ + +T D+ +FD+ GFLKS DR+ + Y + TQ++S FI E S+ ++ D LAFFD C+ + M+ E L++ D SEHT ++PP+ LP PLP HG L S P L L+ P N SS R S ++ +R +E+K A+ M K W+ LL Y LWF+ LPG +G+ R L+ A +L M +L PDEVCYRVLL L Q L V L +K A + NA +YG N+ +L E W KL N+ KQ + P + E + D D D+ ++ SAN + E DSSD G + +SD Y
Sbjct: 8 RVADYFVVAGLPDSPKPLEDDLHF---DDAGARSVKP-------KAPITDVAVVIRSLGEEVPAGFTCVETTPTGLS-AELNGASLRGPQVFLCFKRGRDKPPLTDLGVLYEWKEKLKPGCH-----IVQTTPSGRPANISSSSSQRIYITYRRSPKSQPHTSLAVTDVCVIIPGKGETPPHTFCKVDKNLNSSMWGSSIYLCYKKSLAKANAIAYKAGLLCRYPEEDYE---------------SFPLPESV---PMFCLPMGAMIERWPTHTKHSLPVFSTFVLTGASGEKVYGAAIQFYEPHPEESLTDRQRSQLGLTSSDFGNDETKTFYSNKSICLLSHWPFFDSFRSFLTFLY------RYSISGPHAVPIEKHVSHFMQNVPFPSTQRPRILVQLSPHDSLILSQPVSSPLPL-------SGGSLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGLDSRYFDLYVPPADISCVDLDTNTISQKEDKKALTWKILPRRACKYL--------------LNTLSKLYQQLI--EGGQVNRDDVQMNHAVTDDELYGGKSLHTLELEIQEAFLRLMAAILRGYRSYLQPITQAPSEKTTDVSSLFDLQGFLKSRDRSHQRFYSLMTKTQMFSRFIEECSFVSDKDASLAFFDECVDKLFTTGGKMDGERPEDTRLIELDESHGSEHTVYVNPPE-----------------------LP-------------------------PLP--------HGEEYPLRYSYSRFPVLSVELLEPLEGPNPSSAGTASRHSSPSSPTAIFRRSQQEIKSAQRMAK-THSSVPQMWSKCLLRHCYGLWFICLPGFVGNCHSKV---------RALRTAYDVLRKMQEKKLQAPDEVCYRVLLQLCGQYSQPVLAVRVLFEMKKAGVQPNAITYGYYNKAVL--ESTWPSTTRGGYFLWGKLRNVLLGVLQFKQARRKRRTPHR----EPQLSDGSDLDTVSHGSMDSANDSAERTSIDTDFTKMDSSDDGFSTGGQSDQGY 955 HSP 2 Score: 112.464 bits (280), Expect = 3.966e-24 Identity = 96/355 (27.04%), Postives = 146/355 (41.13%), Query Frame = 2
Query: 4352 IHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCND----------------------SNRTHSNSPSYRFTPKLNFL------VYINHPDPQNGKINTQSLAYTNT-------VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYL-----SDAIEALI-LIRIESGENANIMSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
I V M++CS C C VYD++IM GW+ NDS+L S CP+C SN S +PK N V HP +G A T V YLSP VL KELES+L EG+ A+ + +H I++WNL+WY+ RL LP++L + + L++ SS ++ V+ QV+V + W+ P Y A + G+ + +++ SD + + +I++ E RS+YR+L L LG N +N + F+ Y + +L D P + CR+ F
Sbjct: 1343 IEVLMSSCSLCKTCDCLVYDEEIMAGWTANDSNLNSTCPFCGTAFLPFLNAEIKDLKPQNKFSKLSNPVKEEDISATLSPKDNMSEAAQPSVASIHPVETSGSAGVSPPASVPTSASDLVTVPYLSPLVLWKELESLLVNEGDQAISSPSVVDQHPIVFWNLVWYFRRLELPSNLSALI----------LASQHCSSGDQSLPSVSSEDSRQVLVRIMWDNLKLHRDKVQPCYVLWNTHCANSLIRSGLCEEGQLFTVELLQSFVRSIKKSDVYQPMTQIIQLLGPELGFKRQRSLYRDLLFLSLVALGKNNININAFDREYRLAYDRLTPSQVKLTHNCDRTPGAGVMECRRTF 1687
BLAST of C-myc promoter-binding protein vs. Ensembl Medaka
Match: dennd4a (DENN domain containing 4A [Source:NCBI gene;Acc:101171828]) HSP 1 Score: 380.563 bits (976), Expect = 3.655e-107 Identity = 320/1078 (29.68%), Postives = 486/1078 (45.08%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRK----NTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFS---QTKDI--MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFL---LVTPESAMNASSNIRNRR----SVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILEQEQQWSQ----------KLSNLSTST---KQPKCDSDNPDKPIAVEKEGKDEKDCDS-GRETLASANIAPEEAQ--------DSSDSGCNLIMKSDNNY 3229
R+ +YF+++G ++ K + F ++ VK K P+ D+ +V + ++P GF V+ T + A+L G S ++FLCF+ GRDKPP+TD+ + + K K C +++ T +G AN+SSSSS +YI ++R+P + P +LAVTD+C+I+ K E P + +VD ++ S G +I +CYKKS+ K N ++++ ++ P E LPE + FC+P GA +E W + P F TFVLT + ++YGAA+ FYE E+ LT + + + ++ E Y ++S+CLLS WP F +F L F+ + + P+++PIE +S F+ V FP+ Q P IL+Q HD P+ LP +G + L+ L + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++G+DSR+FD + P + C+DL T +I P CKYL LS +++ E Q+ R N DE + + I+E FLR + + R Y++YL P++ + +T D+ +FD+ GFLKS DR+ + Y + TQ++S FI E S+ ++ D LAFFD C+ M+ E L++ D SEHT ++PP+ LP PLP HG L S P L L+ P N SS R S ++ +R +E+K A+ M K W+ LL Y LWF+ LPG +G+ R L+ A +L M +L PDEVCYRVLL L Q L V L +K A + NA +YG N+ +L E W KL N+ KQ + P + E + D D D+ ++ SAN + E DSSD G + +SD Y
Sbjct: 7 RVADYFVVAGLPDSPKPLEDDLHF---DDAGARSVKP-------KAPITDVAVVIRSLGEEVPAGFTCVETTPTGLS-AELNGASLRGPQVFLCFKRGRDKPPLTDLGVLYEWKEKLKPGCH-----IVQTTPSGRPANISSSSSQRIYITYRRSPKSQPHTSLAVTDVCVIIPGKGETPPHTFCKVDKNLNSSMWGSSIYLCYKKSLAKANAIAYKAGLLCRYPEEDYE---------------SFPLPESV---PMFCLPMGAMIERWPTHTKHSLPVFSTFVLTGASGEKVYGAAIQFYEPHPEESLTDRQRSQLGLTSSDFGNDETKTFYSNKSICLLSHWPFFDSFRSFLTFLYRYS-----ISGPHAVPIEKHVSHFMQNVPFPSTQRPRILVQLSPHDSLILSQPVSSPLPL-------SGGSLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGLDSRYFDLYVPPADISCVDLDTNTISQKEDKKALTWKILPRRACKYL--------------LNTLSKLYQQLI--EGGQVNRDDVQMNHAVTDDELYGGKSLHTLELEIQEAFLRLMAAILRGYRSYLQPITQAPSEKTTDVSSLFDLQGFLKSRDRSHQRFYSLMTKTQMFSRFIEECSFVSDKDASLAFFDECVDK---MDGERPEDTRLIELDESHGSEHTVYVNPPE-----------------------LP-------------------------PLP--------HGEEYPLRYSYSRFPVLSVELLEPLEGPNPSSAGTASRHSSPSSPTAIFRRSQQEIKSAQRMAK-THSSVPQMWSKCLLRHCYGLWFICLPGFVGNCHSKV---------RALRTAYDVLRKMQEKKLQAPDEVCYRVLLQLCGQYSQPVLAVRVLFEMKKAGVQPNAITYGYYNKAVL--ESTWPSTTRGGYFLWGKLRNVLLGVLQFKQARRKRRTPHR----EPQLSDGSDLDTVSHGSMDSANDSAERTSIDTDFTKMDSSDDGFSTGGQSDQGY 947 HSP 2 Score: 115.546 bits (288), Expect = 4.554e-25 Identity = 94/334 (28.14%), Postives = 142/334 (42.51%), Query Frame = 2
Query: 4352 IHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCN-------DSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTNT-------VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWE----FASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYL-----SDAIEALI-LIRIESGENANIMSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
I V M++CS C C VYD++IM GW+ NDS+L S CP+C + N + + PS V HP +G A T V YLSP VL KELES+L EG+ A+ + +H I++WNL+WY+ RL LP++L + + LS S SS + QV+V + W+ P Y A + G+ + +++ SD + + +I++ E RS+YR+L L LG N +N + F+ Y + +L D P + CR+ F
Sbjct: 1333 IEVLMSSCSLCKTCDCLVYDEEIMAGWTANDSNLNSTCPFCGTAFLPFLNDNMSEAAQPS----------VASIHPVETSGSAGVSPPASVPTSASDLVTVPYLSPLVLWKELESLLVNEGDQAISSPSVVDQHPIVFWNLVWYFRRLELPSNLSALI----------LSLPSVSSEDS----------RQVLVRIMWDNLKLHRDKVQPCYVLWNTHCANSLIRSGLCEEGQLFTVELLQSFVRSIKKSDVYQPMTQIIQLLGPELGFKRQRSLYRDLLFLSLVALGKNNININAFDREYRLAYDRLTPSQVKLTHNCDRTPGAGVMECRRTF 1636
BLAST of C-myc promoter-binding protein vs. Ensembl Medaka
Match: dennd4a (DENN domain containing 4A [Source:NCBI gene;Acc:101171828]) HSP 1 Score: 380.178 bits (975), Expect = 6.705e-107 Identity = 320/1078 (29.68%), Postives = 486/1078 (45.08%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVD-ELFLCFRYGRDKPPITDI---WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR-SKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HD-----HPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKP------------PENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRK----NTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFS---QTKDI--MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFL---LVTPESAMNASSNIRNRR----SVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILEQEQQWSQ----------KLSNLSTST---KQPKCDSDNPDKPIAVEKEGKDEKDCDS-GRETLASANIAPEEAQ--------DSSDSGCNLIMKSDNNY 3229
R+ +YF+++G ++ K + F ++ VK K P+ D+ +V + ++P GF V+ T + A+L G S ++FLCF+ GRDKPP+TD+ + + K K C +++ T +G AN+SSSSS +YI ++R+P + P +LAVTD+C+I+ K E P + +VD ++ S G +I +CYKKS+ K N ++++ ++ P E LPE + FC+P GA +E W + P F TFVLT + ++YGAA+ FYE E+ LT + + + ++ E Y ++S+CLLS WP F +F L F+ + + P+++PIE +S F+ V FP+ Q P IL+Q HD P+ LP +G + L+ L + L V +TE KIL+ S + LT + EAL++MIFPF W YIP L ++ +P P+++G+DSR+FD + P + C+DL T +I P CKYL LS +++ E Q+ R N DE + + I+E FLR + + R Y++YL P++ + +T D+ +FD+ GFLKS DR+ + Y + TQ++S FI E S+ ++ D LAFFD C+ M+ E L++ D SEHT ++PP+ LP PLP HG L S P L L+ P N SS R S ++ +R +E+K A+ M K W+ LL Y LWF+ LPG +G+ R L+ A +L M +L PDEVCYRVLL L Q L V L +K A + NA +YG N+ +L E W KL N+ KQ + P + E + D D D+ ++ SAN + E DSSD G + +SD Y
Sbjct: 8 RVADYFVVAGLPDSPKPLEDDLHF---DDAGARSVKP-------KAPITDVAVVIRSLGEEVPAGFTCVETTPTGLS-AELNGASLRGPQVFLCFKRGRDKPPLTDLGVLYEWKEKLKPGCH-----IVQTTPSGRPANISSSSSQRIYITYRRSPKSQPHTSLAVTDVCVIIPGKGETPPHTFCKVDKNLNSSMWGSSIYLCYKKSLAKANAIAYKAGLLCRYPEEDYE---------------SFPLPESV---PMFCLPMGAMIERWPTHTKHSLPVFSTFVLTGASGEKVYGAAIQFYEPHPEESLTDRQRSQLGLTSSDFGNDETKTFYSNKSICLLSHWPFFDSFRSFLTFLYRYS-----ISGPHAVPIEKHVSHFMQNVPFPSTQRPRILVQLSPHDSLILSQPVSSPLPL-------SGGSLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGLDSRYFDLYVPPADISCVDLDTNTISQKEDKKALTWKILPRRACKYL--------------LNTLSKLYQQLI--EGGQVNRDDVQMNHAVTDDELYGGKSLHTLELEIQEAFLRLMAAILRGYRSYLQPITQAPSEKTTDVSSLFDLQGFLKSRDRSHQRFYSLMTKTQMFSRFIEECSFVSDKDASLAFFDECVDK---MDGERPEDTRLIELDESHGSEHTVYVNPPE-----------------------LP-------------------------PLP--------HGEEYPLRYSYSRFPVLSVELLEPLEGPNPSSAGTASRHSSPSSPTAIFRRSQQEIKSAQRMAK-THSSVPQMWSKCLLRHCYGLWFICLPGFVGNCHSKV---------RALRTAYDVLRKMQEKKLQAPDEVCYRVLLQLCGQYSQPVLAVRVLFEMKKAGVQPNAITYGYYNKAVL--ESTWPSTTRGGYFLWGKLRNVLLGVLQFKQARRKRRTPHR----EPQLSDGSDLDTVSHGSMDSANDSAERTSIDTDFTKMDSSDDGFSTGGQSDQGY 948 HSP 2 Score: 100.908 bits (250), Expect = 1.259e-20 Identity = 68/207 (32.85%), Postives = 94/207 (45.41%), Query Frame = 2
Query: 4352 IHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCND----------------------SNRTHSNSPSYRFTPKLNFL------VYINHPDPQNGKINTQSLAYTNT-------VNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNL 4867
I V M++CS C C VYD++IM GW+ NDS+L S CP+C SN S +PK N V HP +G A T V YLSP VL KELES+L EG+ A+ + +H I++WNL+WY+ RL LP++L + + S S SS + ++LV +
Sbjct: 1336 IEVLMSSCSLCKTCDCLVYDEEIMAGWTANDSNLNSTCPFCGTAFLPFLNAEIKDLKPQNKFSKLSNPVKEEDISATLSPKDNMSEAAQPSVASIHPVETSGSAGVSPPASVPTSASDLVTVPYLSPLVLWKELESLLVNEGDQAISSPSVVDQHPIVFWNLVWYFRRLELPSNLSALILASQHCSSGDQSLPSVSSEDSRQVLVRI 1542
BLAST of C-myc promoter-binding protein vs. Ensembl Medaka
Match: ENSORLT00000026947.1 (C-myc promoter-binding protein [Source:NCBI gene;Acc:101168670]) HSP 1 Score: 376.711 bits (966), Expect = 2.062e-105 Identity = 316/1039 (30.41%), Postives = 482/1039 (46.39%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLY-GKSAVDELFLCFRYGRDKPPITDI-----WAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCS----RSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQ-QILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVS---MLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILEQEQQWS--------QKLSNLSTSTKQPKCDSDNPDKPIAVEKEGKDEKDCD--SGRETLASANIAPEEAQDSSDSG 3196
R+ +YF+++G ++ K D F +++ + K K PV D+ +V + + P GF ++ T + Q ADL G ++FLC+R GRDKPP+TD+ W +KQ LI+ T G SAN+S +SS +YI ++RAPD+ P LAVTDICII+ +K E P + +V+ ++ S G ++ +CYKKS+ K N + ++ + P E LPE + FC+P GA +E W N P F TFV T + ++YGAA+ FYE + LT +++ S + + P CS + +CLLS WP F F + L F+ + + P+++PIE IS F+H V FP+ Q P IL+Q HD + Q + L +G F L++ L E + L V+ +TE KIL+ S + LT EAL++MIFPF W YIP L ++ +P P+++GVDSR+FD + P V C+DL T +I E+ + L + + K L LS +++ + Q L + + + E + + + IRE FLR + + + Y+++L P++ + ++ +FD+ GFLKS DR+ + Y + TQ++ FI E S+ ++ D L FFD C+ ++ E + A L++TD +SEHT + PP+ P LP + P +G P+ SL D P TP+ SS + R S S M +R +E++ A+ M K KY S W+ LL Y LWF+ LP + K R L+ A +L M +L PDEVCYRVL+ L Q L V L +K A + NA +YG N+ +LE S KL N+ + Q K P + + D D D S +SA+ P A D S +G
Sbjct: 7 RVADYFVVAGLTDPSKPLDQEIHF---DDVCHKTAKP-------KAPVTDVAVVIRSLGEEAPPGFTCIETTPTGQS-ADLNNGGLMAPQIFLCYRRGRDKPPLTDLGVLFQWKERLKQG-------CHLIQTTPFGRSANISGNSSQRIYITYRRAPDSQPHAALAVTDICIIIPSKGETPPHTFCKVEKNLNSSMWGSSVFLCYKKSVAKTNAVVYKAGLFSRYPEEDYE---------------SFPLPESV---PLFCLPMGAIIECWPANTKYSLPIFSTFVFTGASGEKVYGAAIQFYEPYPPECLTNQQLCRLGLLSAEQLSNTNPAGSSCSVHTNKCICLLSHWPFFDAFRKFLTFLYRYS-----ISGPHALPIEKHISHFMHKVPFPSSQRPRILVQLSPHDSLMLSQPASSPLPL--SGGRFSTLLQNLGPENAVTLLVFAVTEHKILVHSLRPAVLTSATEALVSMIFPFHWQCPYIPLCPLALADVLSAPCPFIVGVDSRYFDLYDPPPDVSCVDLDTNTIFHCEDK-RGLTWKILPKKPCKNLLNV-LSRLYQELLDGQCQLDGLLELSMSDSPELSCGKSLHTLELEIREAFLRFMAAILKGYRSFLRPITQAPSEKATDASSLFDLQGFLKSRDRSHQKFYSLMTKTQMFIRFIEECSFVSDKDASLVFFDECVDK---VDGEKLEDARLIETDESHRSEHTVFITPPE-------------LPP-------LPGVEEHPLCYRYDG-------------FPV-----------LSLDLFDPVAP----TPDGLQAPSSRLSARHSCPSSPAPMFRRTKQEIRSAQKMAK--KYSSIPQLWSKCLLRHCYGLWFICLPAYV---------KVCHSKVRALRSAYDVLRKMQTKKLQPPDEVCYRVLMQLCGQYGQPVLAVRVLFEMKKAGVHPNAVTYGYYNKAVLESTWPSSNRGGYFLWMKLRNVLLAVAQFKRSLSRPA--LLTQSPLSDVSDLDAVSHGSLDSSADPGPSAADDRSSTG 936 HSP 2 Score: 77.411 bits (189), Expect = 1.504e-13 Identity = 72/261 (27.59%), Postives = 119/261 (45.59%), Query Frame = 2
Query: 4517 FTPKL----NFLVYINHP-DPQNGKINTQSLAYTNTVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILV-----NLTGFEQVV--VFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTL 5260
F+P+L + +N P DP N + + S TV YLSP VL KELES+L+ EG+ + +++ + H I+YWNL+WY+ RL LP++L + +S S + +L+ NL + V +++ W +T N Y VT E A + + + I N +S + L+++ S RS+YR++ L LG + ++ D F+ Y + +L D PPS +
Sbjct: 1640 FSPRLQTSGSLPTRLNEPVDPLNVEWSVHS-PEPVTVPYLSPLVLWKELESLLENEGDPVITEADMVDHHPIIYWNLIWYFRRLDLPSNLPGLVLTSEHCNRDSQIPHHWMSEDSKHVLIQILWDNLKLHQDPVRPLYILW---NTYNVGYS-VTRPVPEEEKA-FSEEVLQSVVRSIQRNDVSRPMAQ--LLQLHSQTLGVRRQRSLYRDILFLSLVALGKDNIDIDAFDREYKLAFDRLAPNLVKLTHNCDRPPSTGVM 1892
BLAST of C-myc promoter-binding protein vs. Ensembl Medaka
Match: ENSORLT00000026830.1 (C-myc promoter-binding protein [Source:NCBI gene;Acc:101168670]) HSP 1 Score: 376.326 bits (965), Expect = 2.338e-105 Identity = 315/1035 (30.43%), Postives = 483/1035 (46.67%), Query Frame = 2
Query: 191 RICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLY-GKSAVDELFLCFRYGRDKPPITDIWA-FNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFR--SKNETQTSEPYKIYCS----RSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWD-HDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQ-QILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDI-----MFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVS---MLKRPFEELKQARLMGKEAKYGS-SYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSEL--LKHADL--NAFSYGLCNQIILEQEQQWS--------QKLSNLSTSTKQPKCDSDNPDKPIAVEKEGKDEKDCD--SGRETLASANIAPEEAQDSSDSG 3196
R+ +YF+++G ++ K D F +++ + K K PV D+ +V + + P GF ++ T + Q ADL G ++FLC+R GRDKPP+TD+ F K++ + LI+ T G SAN+S +SS +YI ++RAPD+ P LAVTDICII+ +K E P + +V+ ++ S G ++ +CYKKS+ K N + ++ + P E LPE + FC+P GA +E W N P F TFV T + ++YGAA+ FYE + LT +++ S + + P CS + +CLLS WP F F + L F+ + + P+++PIE IS F+H V FP+ Q P IL+Q HD + Q + L +G F L++ L E + L V+ +TE KIL+ S + LT EAL++MIFPF W YIP L ++ +P P+++GVDSR+FD + P V C+DL T +I E+ + L + + K L LS +++ + Q L + + + E + + + IRE FLR + + + Y+++L P++ + ++ +FD+ GFLKS DR+ + Y + TQ++ FI E S+ ++ D L FFD C+ ++ E + A L++TD +SEHT + PP+ P LP + P +G P+ SL D P TP+ SS + R S S M +R +E++ A+ M K KY S W+ LL Y LWF+ LP + K R L+ A +L M +L PDEVCYRVL+ L Q L V L +K A + NA +YG N+ +LE S KL N+ + Q K P + + D D D S +SA+ P A D S +G
Sbjct: 7 RVADYFVVAGLTDPSKPLDQEIHF---DDVCHKTAKP-------KAPVTDVAVVIRSLGEEAPPGFTCIETTPTGQS-ADLNNGGLMAPQIFLCYRRGRDKPPLTDLGVLFQWKER---LKQGCHLIQTTPFGRSANISGNSSQRIYITYRRAPDSQPHAALAVTDICIIIPSKGETPPHTFCKVEKNLNSSMWGSSVFLCYKKSVAKTNAVVYKAGLFSRYPEEDYE---------------SFPLPESV---PLFCLPMGAIIECWPANTKYSLPIFSTFVFTGASGEKVYGAAIQFYEPYPPECLTNQQLCRLGLLSAEQLSNTNPAGSSCSVHTNKCICLLSHWPFFDAFRKFLTFLYRYS-----ISGPHALPIEKHISHFMHKVPFPSSQRPRILVQLSPHDSLMLSQPASSPLPL--SGGRFSTLLQNLGPENAVTLLVFAVTEHKILVHSLRPAVLTSATEALVSMIFPFHWQCPYIPLCPLALADVLSAPCPFIVGVDSRYFDLYDPPPDVSCVDLDTNTIFHCEDK-RGLTWKILPKKPCKNLLNV-LSRLYQELLDGQCQLDGLLELSMSDSPELSCGKSLHTLELEIREAFLRFMAAILKGYRSFLRPITQAPSEKATDASSLFDLQGFLKSRDRSHQKFYSLMTKTQMFIRFIEECSFVSDKDASLVFFDECVDK---VDGEKLEDARLIETDESHRSEHTVFITPPE-------------LPP-------LPGVEEHPLCYRYDG-------------FPV-----------LSLDLFDPVAP----TPDGLQAPSSRLSARHSCPSSPAPMFRRTKQEIRSAQKMAK--KYSSIPQLWSKCLLRHCYGLWFICLPAYV---------KVCHSKVRALRSAYDVLRKMQTKKLQPPDEVCYRVLMQLCGQYGQPVLAVRVLFEMKKAGVHPNAVTYGYYNKAVLESTWPSSNRGGYFLWMKLRNVLLAVAQFKRSLSRPA--LLTQSPLSDVSDLDAVSHGSLDSSADPGPSAADDRSSTG 936 HSP 2 Score: 105.531 bits (262), Expect = 4.604e-22 Identity = 93/363 (25.62%), Postives = 158/363 (43.53%), Query Frame = 2
Query: 4349 SIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCND-----------SNRTHSNSP-----------------------------SYRFTPKL----NFLVYINHP-DPQNGKINTQSLAYTNTVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILV-----NLTGFEQVV--VFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLG-NQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFF 5278
++ + +++CS+C C VYD++IM GW+ +DS+L + CP+C + R +P + F+P+L + +N P DP N + + S TV YLSP VL KELES+L+ EG+ + +++ + H I+YWNL+WY+ RL LP++L + +S S + +L+ NL + V +++ W +T N Y VT E A + + + I N +S + L+++ S RS+YR++ L LG + ++ D F+ Y + +L D PPS + R+ F
Sbjct: 1491 AMELLISSCSRCKTCDCLVYDEEIMAGWTADDSNLNTTCPFCGNPFLPFLNVEIRDMRGPGRAPGISIPTERHQGALSSSMTRSVTIFGPLEETSSFSPRLQTSGSLPTRLNEPVDPLNVEWSVHS-PEPVTVPYLSPLVLWKELESLLENEGDPVITEADMVDHHPIIYWNLIWYFRRLDLPSNLPGLVLTSEHCNRDSQIPHHWMSEDSKHVLIQILWDNLKLHQDPVRPLYILW---NTYNVGYS-VTRPVPEEEKA-FSEEVLQSVVRSIQRNDVSRPMAQ--LLQLHSQTLGVRRQRSLYRDILFLSLVALGKDNIDIDAFDREYKLAFDRLAPNLVKLTHNCDRPPSTGVMEVRRTF 1845
BLAST of C-myc promoter-binding protein vs. Planmine SMEST
Match: SMESG000017117.1 (SMESG000017117.1) HSP 1 Score: 3381.65 bits (8767), Expect = 0.000e+0 Identity = 1700/1708 (99.53%), Postives = 1705/1708 (99.82%), Query Frame = 2
Query: 173 MSLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADLNAFSYGLCNQIILEQEQQWSQKLSNLSTSTKQPKCDSDNPDKPIAVEKEGKDEKDCDSGRETLASANIAPEEAQDSSDSGCNLIMKSDNNYSIEIGGKPVQLRGRFQTPRNHKDRVSQLIISSPADLYSSNDVEKNRQFFDPKAGIIMSTADRSLSPFLKMYQSPKSNEEIDKPKVIPAIDSTTTAIITRTPFSEERSELHSSFLMKKRLSIXXXXXXXXXXXXXXXXXXXIVRDTVPYXXXXXXXXXXXXXXXXXTQSEFSSDKITNKTRASLRQIKIAANKSIRSMRNIVSTMGSGSWLTPSDGKFSSDSSQKLLPAGLPNAFRPWNQNNSSHGNGMNTENRLKATASADLLDTLGNDQVKLHENKVCANTVQQLRRNTNLSGMHWTNSESCESLSSDKFEQDSSTNSLETEPAFVFIDKIYDKVTGSLGAIRLPTGKYWPDSQIDGDSPAAAAAPCIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTNTVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI 5296
MSLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSA DELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLSSSSSNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYEEIDEDELTTEEIAYFRSKNE QTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYVKVLPKSVLKSLKYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRK+FPKRLCSDLMLPSIHITPSNIDE+GEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADLNAFSYGLCNQIILEQEQQWSQKLSNLSTSTKQPKCDSDNPDKPIAVEKEGKDEKDCDSGRETLASANIAPEEAQDSSDSGCNLIMKSDNNYSIEIGGKPVQLRGRFQTPRNHKDRVSQLIISSPADLYSSNDVEKNRQFFDPKAGIIMSTADRSLSPFLKMYQSPKSNEEIDKPKVIPAIDSTTTAIITRTPFSEERSELHSSFLMKKRLSIDNNSTSSDKDQSSNISSSDIVRDTVPYSDISSDLSRSRISDSRLTQSEFSSDKITNKTRASLRQIKIAANKSIRSMRNIVSTMGSGSWLTPSDGKFSSDSSQKLLPAGLPNAFRPWNQNNSSHGNGMNTENRLKATASADLLDTLGNDQVKLHENKVCANTVQQLR+NTNLSGMHWTNSESCESLSSDKFEQDSSTNSLETEPAFVFIDKIYDKVTGSLGAIRLPTGKYWPDSQIDGDSPAAAAAP IECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTNTVNYLSPFVLRKELESVLDQEGE+ALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGIT+NYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI
Sbjct: 1 MSLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAADELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLSSSSSNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYEEIDEDELTTEEIAYFRSKNEIQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYVKVLPKSVLKSLKYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKIFPKRLCSDLMLPSIHITPSNIDESGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADLNAFSYGLCNQIILEQEQQWSQKLSNLSTSTKQPKCDSDNPDKPIAVEKEGKDEKDCDSGRETLASANIAPEEAQDSSDSGCNLIMKSDNNYSIEIGGKPVQLRGRFQTPRNHKDRVSQLIISSPADLYSSNDVEKNRQFFDPKAGIIMSTADRSLSPFLKMYQSPKSNEEIDKPKVIPAIDSTTTAIITRTPFSEERSELHSSFLMKKRLSIDNNSTSSDKDQSSNISSSDIVRDTVPYSDISSDLSRSRISDSRLTQSEFSSDKITNKTRASLRQIKIAANKSIRSMRNIVSTMGSGSWLTPSDGKFSSDSSQKLLPAGLPNAFRPWNQNNSSHGNGMNTENRLKATASADLLDTLGNDQVKLHENKVCANTVQQLRKNTNLSGMHWTNSESCESLSSDKFEQDSSTNSLETEPAFVFIDKIYDKVTGSLGAIRLPTGKYWPDSQIDGDSPAAAAAPYIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTNTVNYLSPFVLRKELESVLDQEGEVALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITSNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI 1708
BLAST of C-myc promoter-binding protein vs. Planmine SMEST
Match: SMESG000017117.1 (SMESG000017117.1) HSP 1 Score: 3341.21 bits (8662), Expect = 0.000e+0 Identity = 1685/1708 (98.65%), Postives = 1690/1708 (98.95%), Query Frame = 2
Query: 173 MSLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAVDELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLXXXXXNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYXXXXXXXXXXXXXAYFRSKNETQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYXXXXXXXXXXXXXYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKVFPKRLCSDLMLPSIHITPSNIDENGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADLNAFSYGLCNQIILEQEQQWSQKLSNLSTSTKQPKCDSDNPDKPIAVEKEGKDEKDCDSGRETLASANIAPEEAQDSSDSGCNLIMKSDNNYSIEIGGKPVQLRGRFQTPRNHKDRVSQLIISSPADLYSSNDVEKNRQFFDPKAGIIMSTADRSLSPFLKMYQSPKSNEEIDKPKVIPAIDSTTTAIITRTPFSEERSELHSSFLMKKRLSIXXXXXXXXXXXXXXXXXXXIVRDTVPYXXXXXXXXXXXXXXXXXTQSEFSSDKITNKTRASLRQIKIAANKSIRSMRNIVSTMGSGSWLTPSDGKFSSDSSQKLLPAGLPNAFRPWNQNNSSHGNGMNTENRLKATASADLLDTLGNDQVKLHENKVCANTVQQLRRNTNLSGMHWTNSESCESLSSDKFEQDSSTNSLETEPAFVFIDKIYDKVTGSLGAIRLPTGKYWPDSQIDGDSPAAAAAPCIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTNTVNYLSPFVLRKELESVLDQEGEIALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITNNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI 5296
MSLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSA DELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLSSSSSNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYEEIDEDELTTEEIAYFRSKNE QTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYVKVLPKSVLKSLKYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRK+FPKRLCSDLMLPSIHITPSNIDE+GEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADLNAFSYGLCNQIILEQEQQWSQKLSNLSTSTKQPKCDSDNPDKPIAVEKEGKDEKDCDSGRETLASANIAPEEAQDSSDSGCNLIMKSDNNYSIEIGGKPVQLRGRFQTPRNHKDRVSQLIISSPADLYSSNDVEKNRQFFDPKAGIIMSTADRSLSPFLKMYQSPKSNEEIDKPKVIPAIDSTTTAIITRTPFSEERSELHSSFLMKKRLSIDNNSTSSDKDQSSNISSSDIVRDTVPYSDISSDLSRSRISDSRLTQSEFSSDKITNKTRASLRQIKIAANKSIRSMRNIVSTMGSGSWLTPSDGKFSSDSSQKLLPAGLPNAFRPWNQNNSSHGNGMNTENRLKATASADLLDTLGND QLR+NTNLSGMHWTNSESCESLSSDKFEQDSSTNSLETEPAFVFIDKIYDKVTGSLGAIRLPTGKYWPDSQIDGDSPAAAAAP IECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTNTVNYLSPFVLRKELESVLDQEGE+ALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGIT+NYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI
Sbjct: 1 MSLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYKEPVVDIKIVNSNSINKLPDGFHIVQNTYSNQHRADLYGKSAADELFLCFRYGRDKPPITDIWAFNMKQKNTCTQDQWTLIEKTVNGHSANLSSSSSNPLYIAFKRAPDNAPVDNLAVTDICIILANKNELCPPAYSRVDVSIKRSPLGHTINICYKKSMVKQNVLSFQPEIIYCLPATSTEPIVDIYNPDRGSVKSELCLPEDICDAASFCMPWGATLESWSLNRSIPKPSFLTFVLTNVNYNRMYGAAVLFYEEIDEDELTTEEIAYFRSKNEIQTSEPYKIYCSRSLCLLSRWPLFQTFNQVLLFIIQEDEKQRFTNPPNSIPIETFISQFLHTVAFPTPQAPNILLQWDHDHPIGIQLPTDALSRFGTGENFYHLVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGVDSRFFDFFRLPEGVGCIDLITKSIKPPENNCKYLDYVKVLPKSVLKSLKYGLSNCKTKVVSFEKQQILRKNTGNVMDEFTILRKRENIGESIRECFLRAVILMFRNYQNYLIPVSFSQTKDIMFDIDGFLKSVDRNCRILYQAIFDTQLWSNFILERSYATEFDDGLAFFDRCIKNMRDMNDETVNAASLLQTDSVIKSEHTKVLDPPDPVVTKLLNSPRKIFPKRLCSDLMLPSIHITPSNIDESGEDNNLSDLNYTTPLPINSEKHVEHGSTASLSTPDSTIPFLLVTPESAMNASSNIRNRRSVKVSMLKRPFEELKQARLMGKEAKYGSSYAWAGHLLSSSYCLWFLSLPGLIGHVEETAGLKETGLAERILQLALMLLDTMNVNRLSLPDEVCYRVLLILIHQLRPIRLHVSELLKHADLNAFSYGLCNQIILEQEQQWSQKLSNLSTSTKQPKCDSDNPDKPIAVEKEGKDEKDCDSGRETLASANIAPEEAQDSSDSGCNLIMKSDNNYSIEIGGKPVQLRGRFQTPRNHKDRVSQLIISSPADLYSSNDVEKNRQFFDPKAGIIMSTADRSLSPFLKMYQSPKSNEEIDKPKVIPAIDSTTTAIITRTPFSEERSELHSSFLMKKRLSIDNNSTSSDKDQSSNISSSDIVRDTVPYSDISSDLSRSRISDSRLTQSEFSSDKITNKTRASLRQIKIAANKSIRSMRNIVSTMGSGSWLTPSDGKFSSDSSQKLLPAGLPNAFRPWNQNNSSHGNGMNTENRLKATASADLLDTLGND---------------QLRKNTNLSGMHWTNSESCESLSSDKFEQDSSTNSLETEPAFVFIDKIYDKVTGSLGAIRLPTGKYWPDSQIDGDSPAAAAAPYIECTQSIHVHMTTCSQCANCQRPVYDDDIMNGWSYNDSDLQSLCPYCNDSNRTHSNSPSYRFTPKLNFLVYINHPDPQNGKINTQSLAYTNTVNYLSPFVLRKELESVLDQEGEVALLKSEFLYEHGILYWNLLWYYSRLGLPTHLLSFLTIWLKRKGESLSAASQSSRNKYEILVNLTGFEQVVVFLFWEFASTSNPLYRCVTNSAAMEHMAPGIKSRINEALTGITSNYLSDAIEALILIRIESGENANIMSRSIYRELFCLITAVLGNQVNYDVFNFTYNSPWQQLKRKYQAYVKTHDNPPSEQTLFCRKFFRPLQLI 1693
BLAST of C-myc promoter-binding protein vs. Planmine SMEST
Match: SMESG000072343.1 (SMESG000072343.1) HSP 1 Score: 54.299 bits (129), Expect = 1.328e-6 Identity = 24/75 (32.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query: 1457 LVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGV 1681
L+ +L +E +I+++ +L E ++++ S L +AE + ++FPF WS VY P L L H + +P P+++G+
Sbjct: 306 LLEVLGLESLIRIYSCVLLEYRVVILSQDYRLLMLVAECITCLLFPFVWSHVYAPILPLAARHFLNAPVPFIMGI 380
BLAST of C-myc promoter-binding protein vs. Planmine SMEST
Match: SMESG000072343.1 (SMESG000072343.1) HSP 1 Score: 54.299 bits (129), Expect = 1.332e-6 Identity = 24/75 (32.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query: 1457 LVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGV 1681
L+ +L +E +I+++ +L E ++++ S L +AE + ++FPF WS VY P L L H + +P P+++G+
Sbjct: 306 LLEVLGLESLIRIYSCVLLEYRVVILSQDYRLLMLVAECITCLLFPFVWSHVYAPILPLAARHFLNAPVPFIMGI 380
BLAST of C-myc promoter-binding protein vs. Planmine SMEST
Match: SMESG000072343.1 (SMESG000072343.1) HSP 1 Score: 54.299 bits (129), Expect = 1.348e-6 Identity = 24/75 (32.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query: 1457 LVRMLDVEQIIQLFVYMLTEQKILLTSTCNSDLTGIAEALIAMIFPFKWSVVYIPFLYLRCIHIIQSPSPYLIGV 1681
L+ +L +E +I+++ +L E ++++ S L +AE + ++FPF WS VY P L L H + +P P+++G+
Sbjct: 306 LLEVLGLESLIRIYSCVLLEYRVVILSQDYRLLMLVAECITCLLFPFVWSHVYAPILPLAARHFLNAPVPFIMGI 380 The following BLAST results are available for this feature:
BLAST of C-myc promoter-binding protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of C-myc promoter-binding protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of C-myc promoter-binding protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of C-myc promoter-binding protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of C-myc promoter-binding protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of C-myc promoter-binding protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of C-myc promoter-binding protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of C-myc promoter-binding protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of C-myc promoter-binding protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of C-myc promoter-binding protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of C-myc promoter-binding protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of C-myc promoter-binding protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of C-myc promoter-binding protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of C-myc promoter-binding protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30023689 ID=SMED30023689|Name=C-myc promoter-binding protein|organism=Schmidtea mediterranea sexual|type=transcript|length=5795bpback to top protein sequence of SMED30023689-orf-1 >SMED30023689-orf-1 ID=SMED30023689-orf-1|Name=SMED30023689-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1710bp MSLNDRRICEYFLISGFSNTRKAYDLSQIFYQGEEIVNADVKITEDFFHYback to top Annotated Terms
The following terms have been associated with this transcript:
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