activin receptor 1

Overview
Nameactivin receptor 1 (AGC30582.1)
Smed IDSMED30023675
Length (bp)2128
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of activin receptor 1 (SMED30023675) t-SNE clustered cells

Violin plots show distribution of expression levels for activin receptor 1 (SMED30023675) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of activin receptor 1 (SMED30023675) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for activin receptor 1 (SMED30023675) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30023675

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30023675h1SMcG0014277 dd_Smed_v4_3426_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30023675h1SMcG0014277 dd_Smed_v4_3426_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30023675h1SMcG0014277 dd_Smed_v4_3426_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of activin receptor 1 vs. Ensembl Human
Match: TGFBR1 (transforming growth factor beta receptor 1 [Source:HGNC Symbol;Acc:HGNC:11772])

HSP 1 Score: 339.347 bits (869), Expect = 3.849e-109
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:   99 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 425          
BLAST of activin receptor 1 vs. Ensembl Human
Match: TGFBR1 (transforming growth factor beta receptor 1 [Source:HGNC Symbol;Acc:HGNC:11772])

HSP 1 Score: 339.347 bits (869), Expect = 2.943e-108
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  168 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 494          
BLAST of activin receptor 1 vs. Ensembl Human
Match: TGFBR1 (transforming growth factor beta receptor 1 [Source:HGNC Symbol;Acc:HGNC:11772])

HSP 1 Score: 339.347 bits (869), Expect = 3.212e-108
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  172 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 498          
BLAST of activin receptor 1 vs. Ensembl Human
Match: TGFBR1 (transforming growth factor beta receptor 1 [Source:HGNC Symbol;Acc:HGNC:11772])

HSP 1 Score: 330.102 bits (845), Expect = 1.122e-105
Identity = 155/312 (49.68%), Postives = 219/312 (70.19%), Query Frame = 1
Query:  880 GMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  115 GLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 417          
BLAST of activin receptor 1 vs. Ensembl Human
Match: ACVR1B (activin A receptor type 1B [Source:HGNC Symbol;Acc:HGNC:172])

HSP 1 Score: 330.487 bits (846), Expect = 2.095e-105
Identity = 161/322 (50.00%), Postives = 221/322 (68.63%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + LS SGSG G+P+  +RT A  I L + +G+GRFG VW G+W G +VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + ++IE  +K+  S  +GLA+LH EI G  GKPGIAHRDLKS+NILVK  G C I DLGLAVR      T+D+     VGT+RYMAPE++ + I   +M +    ++FK ADIY+  LV WEI RRC    ++     Y++PY +LV +DPSIEEM+ ++CD+K+RP I + W +   L+ + K +RE W+   A+RL  +R+KK ++ 
Sbjct:  132 YDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETI---NMKH---FDSFKCADIYALGLVYWEIARRCNSGGVH---EEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQ 444          
BLAST of activin receptor 1 vs. Ensembl Celegans
Match: sma-6 (Serine/threonine-protein kinase sma-6 [Source:UniProtKB/Swiss-Prot;Acc:Q09488])

HSP 1 Score: 233.032 bits (593), Expect = 5.439e-67
Identity = 138/371 (37.20%), Postives = 200/371 (53.91%), Query Frame = 1
Query:  838 IENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDR-RDNGLATELWLVTDYHENGSLFEYL-RAHIISIEQAVKMTRSITNGLAYLHTEINGLDG--KPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNN--VGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCEC---------------------------SSLNIS-----------------ASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIM 1800
            +E+   L  SGSG G   + +RT   D+++I+ +G+GR+G V    + G  VAVK F + DE SW  E+D+YQ N + H N+L FV  D   +    T++ L+TDYHE GSL +YL R   ++ ++A+++  S   G+ +LH  ++G     KP IAHRD+KS+NI+VK    CCI DLGLA+R   D    +  N  VGT+RYMAPE+I +K+   D         FK ADIYS +LV+WE+  R E                            SS NIS                 A  +  P+  +V NDP+ +EM  +IC R+IRPP + +W N+  L ++SK + +SW   P  R + ++LKK M
Sbjct:  238 MESKSMLEDSGSGSGQAALIQRTVRQDLTIIKTIGQGRYGEVRKALYRGSYVAVKTFYTTDEDSWKNERDVYQTNMINHENILQFVAADIWSEEDSMTKMLLITDYHELGSLSDYLCREETLTTDEALRLIHSCICGIEHLHAAVHGTGSFRKPEIAHRDIKSKNIIVKRPNVCCIADLGLALRYQNDKILPEKFNVQVGTKRYMAPELISNKLNPKD------FSQFKMADIYSMALVMWEVAIRVEVNTCEEVLTVDETSPDHSASSGIGESVSSSGNISRMHLQKTNVEGHSTSLKAKQHVPPFDGIVHNDPNFDEMNDVICVRRIRPPPDLAWKNVPALNELSKLMEDSWHSIPHFRHSALKLKKEM 602          
BLAST of activin receptor 1 vs. Ensembl Celegans
Match: daf-1 (Cell surface receptor daf-1 [Source:UniProtKB/Swiss-Prot;Acc:P20792])

HSP 1 Score: 231.491 bits (589), Expect = 3.622e-66
Identity = 124/319 (38.87%), Postives = 189/319 (59.25%), Query Frame = 1
Query:  865 SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGL--DGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNN----VGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMN 1803
            SGSG G   + + T    I L   VG GRFG V  G + G+ VAVK+F++ DE ++ +E ++++   LRH NVL ++ +DR D G  TELWLVT+YH +GSL ++L  + ++IE    + RS  +GLA+LH +I G     KP +AHRD+KS+NI+VK+   C IGDLGL++   ED ++  + N     GT RY+APE IL+  +Q  +      E+++ AD+YS+SLV+WE L RCE   +    +A  +PY      DP   +M  ++C R++RP  N  W +   +K I + ++  W   P++R      +K M+
Sbjct:  275 SGSGMGPTTLHKLTIGGQIRLTGRVGSGRFGNVSRGDYRGEAVAVKVFNALDEPAFHKETEIFETRMLRHPNVLRYIGSDRVDTGFVTELWLVTEYHPSGSLHDFLLENTVNIETYYNLMRSTASGLAFLHNQIGGSKESNKPAMAHRDIKSKNIMVKNDLTCAIGDLGLSLSKPEDAASDIIANENYKCGTVRYLAPE-ILNSTMQFTV-----FESYQCADVYSFSLVMWETLCRCEDGDVLPREAATVIPYIEWTDRDPQDAQMFDVVCTRRLRPTENPLWKDHPEMKHIMEIIKTCWNGNPSARFTSYICRKRMD 587          
BLAST of activin receptor 1 vs. Ensembl Celegans
Match: daf-1 (Cell surface receptor daf-1 [Source:UniProtKB/Swiss-Prot;Acc:P20792])

HSP 1 Score: 228.024 bits (580), Expect = 5.657e-65
Identity = 122/318 (38.36%), Postives = 188/318 (59.12%), Query Frame = 1
Query:  865 SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGL--DGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTR---RYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMN 1803
            SGSG G   + + T    I L   VG GRFG V  G + G+ VAVK+F++ DE ++ +E ++++   LRH NVL ++ +DR D G  TELWLVT+YH +GSL ++L  + ++IE    + RS  +GLA+LH +I G     KP +AHRD+KS+NI+VK+   C IGDLGL++   ED ++  + N   +   RY+APE IL+  +Q  +      E+++ AD+YS+SLV+WE L RCE   +    +A  +PY      DP   +M  ++C R++RP  N  W +   +K I + ++  W   P++R      +K M+
Sbjct:  275 SGSGMGPTTLHKLTIGGQIRLTGRVGSGRFGNVSRGDYRGEAVAVKVFNALDEPAFHKETEIFETRMLRHPNVLRYIGSDRVDTGFVTELWLVTEYHPSGSLHDFLLENTVNIETYYNLMRSTASGLAFLHNQIGGSKESNKPAMAHRDIKSKNIMVKNDLTCAIGDLGLSLSKPEDAASDIIANENYKCGTRYLAPE-ILNSTMQFTV-----FESYQCADVYSFSLVMWETLCRCEDGDVLPREAATVIPYIEWTDRDPQDAQMFDVVCTRRLRPTENPLWKDHPEMKHIMEIIKTCWNGNPSARFTSYICRKRMD 586          
BLAST of activin receptor 1 vs. Ensembl Celegans
Match: daf-4 (Cell surface receptor daf-4 [Source:UniProtKB/Swiss-Prot;Acc:P50488])

HSP 1 Score: 145.206 bits (365), Expect = 1.013e-36
Identity = 109/372 (29.30%), Postives = 174/372 (46.77%), Query Frame = 1
Query:  892 MTRRTAATDISLIQAVGEGRFGTVWLGKWNGDN-----VAVKIFSSRDEVSWAREKDMYQQ--NFLR-HSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPG--IAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLD-LNNVGTRRYMAPEIILDKIVQPDMIYNGGLE----AFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEI-------------STLKNQITDLTSCGDFVSNDSAINDTTSYHCKSP 1923
            M        I+  Q + +GRFG V+  ++  D+     VAVK  +   + S+  EK ++ +   + + + +++ FV  ++    +  E W+VT++HE  SL+E L+ ++ISI  A ++  S+ +GL +LH +     G P   I HRD+KS+NILVKS    CI D GLA     D    D L  VGT+RYM+PE++            G  E    AFK  D+YS  LV+WE++ R +    +     Y+MP+Q ++  DP+I  M++ +  +K RP           +  + K   E W  E  +R+            WN I             S++KN+  D     +       I +   YH  SP
Sbjct:   78 MVETPKELPITDFQLISKGRFGKVFKAQYTPDSGEKRLVAVKKLNEFQKASFLAEKRIFDELNEYPKWYKSIVEFVCAEK----IGDEYWIVTEFHERLSLYELLKNNVISITSANRIIMSMIDGLQFLHDDRPYFFGHPKKPIIHRDIKSKNILVKSDMTTCIADFGLARIYSYDIEQSDLLGQVGTKRYMSPEML-----------EGATEFTPTAFKAMDVYSMGLVMWEVISRTKLHQTD-EPPNYQMPFQ-VIGFDPTIGLMRNYVVSKKERPQWRDEIIKHEYMSLLKKVTEEMWDPEACARITA---GCAFARVWNHIMSSPDSSEGYHSGSSMKNRGVDDVEQSE---KPEGIEEMQHYHASSP 426          
BLAST of activin receptor 1 vs. Ensembl Celegans
Match: daf-4 (Cell surface receptor daf-4 [Source:UniProtKB/Swiss-Prot;Acc:P50488])

HSP 1 Score: 144.821 bits (364), Expect = 2.785e-36
Identity = 109/372 (29.30%), Postives = 174/372 (46.77%), Query Frame = 1
Query:  892 MTRRTAATDISLIQAVGEGRFGTVWLGKWNGDN-----VAVKIFSSRDEVSWAREKDMYQQ--NFLR-HSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPG--IAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLD-LNNVGTRRYMAPEIILDKIVQPDMIYNGGLE----AFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEI-------------STLKNQITDLTSCGDFVSNDSAINDTTSYHCKSP 1923
            M        I+  Q + +GRFG V+  ++  D+     VAVK  +   + S+  EK ++ +   + + + +++ FV  ++    +  E W+VT++HE  SL+E L+ ++ISI  A ++  S+ +GL +LH +     G P   I HRD+KS+NILVKS    CI D GLA     D    D L  VGT+RYM+PE++            G  E    AFK  D+YS  LV+WE++ R +    +     Y+MP+Q ++  DP+I  M++ +  +K RP           +  + K   E W  E  +R+            WN I             S++KN+  D     +       I +   YH  SP
Sbjct:  145 MVETPKELPITDFQLISKGRFGKVFKAQYTPDSGEKRLVAVKKLNEFQKASFLAEKRIFDELNEYPKWYKSIVEFVCAEK----IGDEYWIVTEFHERLSLYELLKNNVISITSANRIIMSMIDGLQFLHDDRPYFFGHPKKPIIHRDIKSKNILVKSDMTTCIADFGLARIYSYDIEQSDLLGQVGTKRYMSPEML-----------EGATEFTPTAFKAMDVYSMGLVMWEVISRTKLHQTD-EPPNYQMPFQ-VIGFDPTIGLMRNYVVSKKERPQWRDEIIKHEYMSLLKKVTEEMWDPEACARITA---GCAFARVWNHIMSSPDSSEGYHSGSSMKNRGVDDVEQSE---KPEGIEEMQHYHASSP 493          
BLAST of activin receptor 1 vs. Ensembl Fly
Match: babo (gene:FBgn0011300 transcript:FBtr0088659)

HSP 1 Score: 327.02 bits (837), Expect = 1.408e-102
Identity = 153/325 (47.08%), Postives = 222/325 (68.31%), Query Frame = 1
Query:  838 IENSFQLSCSGSG-FGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIM 1800
            I +  +++ SGSG  G+P++ +R+ A  + L   +G+GRFG VW G+W G+NVAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLVTDYHENGSLF+YL  H +     + M+ SI  GLA+LH +I G  GKP IAHRDLKS+NILVKS   C IGDLGLAVR +E   ++D+   + VGT+RYMAPE++       + + +   +++K+AD+Y++ L++WEI RRC   ++ +    Y++PY ++V  DPSIEEMK ++C  K RP I + W   + L +++K ++E W+  P +RL  +R+KK +
Sbjct:  275 IHDIIEMTTSGSGSAGLPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVL------DESMNDQHFDSYKRADVYAFGLILWEIARRC---NMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTL 590          
BLAST of activin receptor 1 vs. Ensembl Fly
Match: babo (gene:FBgn0011300 transcript:FBtr0300599)

HSP 1 Score: 326.635 bits (836), Expect = 1.464e-102
Identity = 157/335 (46.87%), Postives = 226/335 (67.46%), Query Frame = 1
Query:  814 YRP-FNG-MKIENSFQLSCSGSG-FGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIM 1800
            Y P  NG   I +  +++ SGSG  G+P++ +R+ A  + L   +G+GRFG VW G+W G+NVAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLVTDYHENGSLF+YL  H +     + M+ SI  GLA+LH +I G  GKP IAHRDLKS+NILVKS   C IGDLGLAVR +E   ++D+   + VGT+RYMAPE++       + + +   +++K+AD+Y++ L++WEI RRC   ++ +    Y++PY ++V  DPSIEEMK ++C  K RP I + W   + L +++K ++E W+  P +RL  +R+KK +
Sbjct:  259 YDPILNGNTTIHDIIEMTTSGSGSAGLPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVL------DESMNDQHFDSYKRADVYAFGLILWEIARRC---NMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTL 584          
BLAST of activin receptor 1 vs. Ensembl Fly
Match: babo (gene:FBgn0011300 transcript:FBtr0088658)

HSP 1 Score: 326.25 bits (835), Expect = 5.577e-102
Identity = 153/325 (47.08%), Postives = 222/325 (68.31%), Query Frame = 1
Query:  838 IENSFQLSCSGSG-FGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIM 1800
            I +  +++ SGSG  G+P++ +R+ A  + L   +G+GRFG VW G+W G+NVAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLVTDYHENGSLF+YL  H +     + M+ SI  GLA+LH +I G  GKP IAHRDLKS+NILVKS   C IGDLGLAVR +E   ++D+   + VGT+RYMAPE++       + + +   +++K+AD+Y++ L++WEI RRC   ++ +    Y++PY ++V  DPSIEEMK ++C  K RP I + W   + L +++K ++E W+  P +RL  +R+KK +
Sbjct:  296 IHDIIEMTTSGSGSAGLPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVL------DESMNDQHFDSYKRADVYAFGLILWEIARRC---NMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTL 611          
BLAST of activin receptor 1 vs. Ensembl Fly
Match: tkv (gene:FBgn0003716 transcript:FBtr0079089)

HSP 1 Score: 288.5 bits (737), Expect = 5.350e-89
Identity = 138/319 (43.26%), Postives = 201/319 (63.01%), Query Frame = 1
Query:  865 SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNN---VGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCEC---SSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMN 1803
            SGSG G+P++ +RT A  I +++ VG+GR+G VWL KW  + VAVK F + +E SW RE ++YQ   +RH N+LGF+  D + NG  T++ L+TDYHE GSL +YL   +I+ ++   +  S+ +GLA+LH EI G  GKP IAHRD+KS+NILVK  G+C I D GLAV+   +   + +     VGTRRYMAPE +L + + P        E FK+AD+YS  LV+WE+ RRC      +   +   Y +PY ++V +DP+ E+M +++C +  RPPI S W   + L  +SK ++E W   P  RL  +R+KK + 
Sbjct:  182 SGSGSGLPLLVQRTIAKQIQMVRLVGKGRYGEVWLAKWRDERVAVKTFFTTEEASWFRETEIYQTVLMRHDNILGFIAADIKGNGSWTQMLLITDYHEMGSLHDYLSMSVINPQKLQLLAFSLASGLAHLHDEIFGTPGKPAIAHRDIKSKNILVKRNGQCAIADFGLAVKYNSELDVIHIAQNPRVGTRRYMAPE-VLSQQLDPKQ-----FEEFKRADMYSVGLVLWEMTRRCYTPVSGTKTTTCEDYALPYHDVVPSDPTFEDMHAVVCVKGFRPPIPSRWQEDDVLATVSKIMQECWHPNPTVRLTALRVKKTLG 494          
BLAST of activin receptor 1 vs. Ensembl Fly
Match: tkv (gene:FBgn0003716 transcript:FBtr0079088)

HSP 1 Score: 288.5 bits (737), Expect = 9.531e-89
Identity = 138/319 (43.26%), Postives = 201/319 (63.01%), Query Frame = 1
Query:  865 SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNN---VGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCEC---SSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMN 1803
            SGSG G+P++ +RT A  I +++ VG+GR+G VWL KW  + VAVK F + +E SW RE ++YQ   +RH N+LGF+  D + NG  T++ L+TDYHE GSL +YL   +I+ ++   +  S+ +GLA+LH EI G  GKP IAHRD+KS+NILVK  G+C I D GLAV+   +   + +     VGTRRYMAPE +L + + P        E FK+AD+YS  LV+WE+ RRC      +   +   Y +PY ++V +DP+ E+M +++C +  RPPI S W   + L  +SK ++E W   P  RL  +R+KK + 
Sbjct:  204 SGSGSGLPLLVQRTIAKQIQMVRLVGKGRYGEVWLAKWRDERVAVKTFFTTEEASWFRETEIYQTVLMRHDNILGFIAADIKGNGSWTQMLLITDYHEMGSLHDYLSMSVINPQKLQLLAFSLASGLAHLHDEIFGTPGKPAIAHRDIKSKNILVKRNGQCAIADFGLAVKYNSELDVIHIAQNPRVGTRRYMAPE-VLSQQLDPKQ-----FEEFKRADMYSVGLVLWEMTRRCYTPVSGTKTTTCEDYALPYHDVVPSDPTFEDMHAVVCVKGFRPPIPSRWQEDDVLATVSKIMQECWHPNPTVRLTALRVKKTLG 516          
BLAST of activin receptor 1 vs. Ensembl Zebrafish
Match: tgfbr1a (transforming growth factor, beta receptor 1 a [Source:ZFIN;Acc:ZDB-GENE-051120-75])

HSP 1 Score: 338.191 bits (866), Expect = 5.471e-108
Identity = 165/353 (46.74%), Postives = 238/353 (67.42%), Query Frame = 1
Query:  757 LPSDRDDNKDYRDNLISPFYRPFNGMKIENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            +PS+ D   D+      PF      +K +  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW G+W G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K++ S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+E+MK ++CD+K+RP I + W +   L+ ++K +RE W+    +RL  +R+KK ++ 
Sbjct:  155 VPSEEDPTMDH------PFLADGTTLK-DLIYDMTTSGSGSGLPLLVQRTIARTIILQESIGKGRFGEVWRGRWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLSLSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMRH---FESFKRADIYALGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEDMKRVVCDQKLRPNIPNRWQSCEALRVMAKIMRECWYANGGARLTALRVKKSLSQ 491          
BLAST of activin receptor 1 vs. Ensembl Zebrafish
Match: tgfbr1b (transforming growth factor, beta receptor 1 b [Source:ZFIN;Acc:ZDB-GENE-091027-1])

HSP 1 Score: 337.035 bits (863), Expect = 1.749e-107
Identity = 164/353 (46.46%), Postives = 239/353 (67.71%), Query Frame = 1
Query:  757 LPSDRDDNKDYRDNLISPFYRPFNGMKIENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            +PS+ D + D+      PF      +K +  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW G+W G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K++ S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI  RC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  160 VPSEEDPSLDH------PFITVGTTLK-DLIYDMTTSGSGSGLPLLVQRTIARTIILQESIGKGRFGEVWRGRWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLSLSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIASRCSIGGIH---EDYQLPYHDLVQSDPSVEEMRRVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 496          
BLAST of activin receptor 1 vs. Ensembl Zebrafish
Match: acvr1ba (activin A receptor type 1Ba [Source:ZFIN;Acc:ZDB-GENE-980526-527])

HSP 1 Score: 329.331 bits (843), Expect = 1.530e-104
Identity = 160/322 (49.69%), Postives = 222/322 (68.94%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            F LS SGSG G+P+  +RT A  I L + +G+GRFG VW G+W G +VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + ++IE  +K++ S  +GLA+LH EI G  GKPGIAHRDLKS+NILVK  G C I DLGLAVR      T+D+     VGT+RYMAPE++ + I   +M +    ++FK ADIY+  LV WEI RRC    ++     Y++PY +LV +DPSIEEM+ ++CD+++RP + + W +   L+ + K +RE W+   A+RL  +R+KK ++ 
Sbjct:  184 FDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTIMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNHYSVTIEGMIKLSLSAASGLAHLHMEILGTQGKPGIAHRDLKSKNILVKKNGTCAIADLGLAVRHESITDTIDIAPNQRVGTKRYMAPEVLDETI---NMKH---FDSFKCADIYALGLVYWEIARRCNAGGIH---EDYQLPYYDLVPSDPSIEEMRKVVCDQRLRPNVPNWWQSYEALRVMGKIMRECWYANGAARLTALRIKKTLSQ 496          
BLAST of activin receptor 1 vs. Ensembl Zebrafish
Match: acvr1bb (activin A receptor type 1Bb [Source:ZFIN;Acc:ZDB-GENE-131120-9])

HSP 1 Score: 328.946 bits (842), Expect = 1.677e-104
Identity = 161/322 (50.00%), Postives = 220/322 (68.32%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + LS SGSG G+P+  +RT A  I L + +G+GRFG VW GKW G +VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHENGSLF+YL  + ++IE  +K+  S  +GLA+LH EI G  GKPGIAHRDLKS+NILVK    C I DLGLAVR      T+D+     VGT+RYMAPE++ + I   +M +    ++FK ADIY+  LV WEI RRC    ++     Y++PY +LV +DPSIEEM+ ++CD+++RP I + W +   L+ + K +RE W+   A+RL  +R+KK ++ 
Sbjct:  172 YDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGKWRGGDVAVKIFSSREERSWFREAEIYQTIMLRHENILGFIAADNKDNGTWTQLWLVSDYHENGSLFDYLNRYSVTIEGMIKLALSAASGLAHLHMEILGTQGKPGIAHRDLKSKNILVKKNCTCAIADLGLAVRHESITDTIDIAPNQRVGTKRYMAPEVLEESI---NMRH---FDSFKCADIYALGLVYWEIARRCNAGGIH---EEYQLPYYDLVPSDPSIEEMRKVVCDQRLRPNIPNWWQSYEALRVMGKIMRECWYANGAARLTALRIKKTLSQ 484          
BLAST of activin receptor 1 vs. Ensembl Zebrafish
Match: acvr1bb (activin A receptor type 1Bb [Source:ZFIN;Acc:ZDB-GENE-131120-9])

HSP 1 Score: 328.561 bits (841), Expect = 2.511e-104
Identity = 161/322 (50.00%), Postives = 220/322 (68.32%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + LS SGSG G+P+  +RT A  I L + +G+GRFG VW GKW G +VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHENGSLF+YL  + ++IE  +K+  S  +GLA+LH EI G  GKPGIAHRDLKS+NILVK    C I DLGLAVR      T+D+     VGT+RYMAPE++ + I   +M +    ++FK ADIY+  LV WEI RRC    ++     Y++PY +LV +DPSIEEM+ ++CD+++RP I + W +   L+ + K +RE W+   A+RL  +R+KK ++ 
Sbjct:  177 YDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGKWRGGDVAVKIFSSREERSWFREAEIYQTIMLRHENILGFIAADNKDNGTWTQLWLVSDYHENGSLFDYLNRYSVTIEGMIKLALSAASGLAHLHMEILGTQGKPGIAHRDLKSKNILVKKNCTCAIADLGLAVRHESITDTIDIAPNQRVGTKRYMAPEVLEESI---NMRH---FDSFKCADIYALGLVYWEIARRCNAGGIH---EEYQLPYYDLVPSDPSIEEMRKVVCDQRLRPNIPNWWQSYEALRVMGKIMRECWYANGAARLTALRIKKTLSQ 489          
BLAST of activin receptor 1 vs. Ensembl Xenopus
Match: tgfbr1 (transforming growth factor beta receptor I [Source:NCBI gene;Acc:548715])

HSP 1 Score: 340.117 bits (871), Expect = 3.997e-109
Identity = 168/356 (47.19%), Postives = 241/356 (67.70%), Query Frame = 1
Query:  757 LPSDRDDNKDYRDNLISPFYRPF--NGMKIEN-SFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            +P+D D + D          RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K++ S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEMK ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  117 VPNDEDPSLD----------RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMLKLSLSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMKKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 453          
BLAST of activin receptor 1 vs. Ensembl Xenopus
Match: tgfbr1 (transforming growth factor beta receptor I [Source:NCBI gene;Acc:548715])

HSP 1 Score: 340.502 bits (872), Expect = 4.401e-109
Identity = 168/356 (47.19%), Postives = 241/356 (67.70%), Query Frame = 1
Query:  757 LPSDRDDNKDYRDNLISPFYRPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            +P+D D + D          RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K++ S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEMK ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  133 VPNDEDPSLD----------RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMLKLSLSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMKKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 469          
BLAST of activin receptor 1 vs. Ensembl Xenopus
Match: tgfbr1 (transforming growth factor beta receptor I [Source:NCBI gene;Acc:548715])

HSP 1 Score: 340.117 bits (871), Expect = 7.506e-109
Identity = 167/353 (47.31%), Postives = 239/353 (67.71%), Query Frame = 1
Query:  757 LPSDRDDNKDYRDNLISPFYRPFNGMKIENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            +P+D D + D       PF      +K +  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K++ S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEMK ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  133 VPNDEDPSLD------RPFISEGTTLK-DLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMLKLSLSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMKKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 469          
BLAST of activin receptor 1 vs. Ensembl Xenopus
Match: tgfbr1 (transforming growth factor beta receptor I [Source:NCBI gene;Acc:548715])

HSP 1 Score: 340.887 bits (873), Expect = 7.772e-109
Identity = 168/356 (47.19%), Postives = 241/356 (67.70%), Query Frame = 1
Query:  757 LPSDRDDNKDYRDNLISPFYRPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            +P+D D + D          RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K++ S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEMK ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  156 VPNDEDPSLD----------RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMLKLSLSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMKKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 492          
BLAST of activin receptor 1 vs. Ensembl Xenopus
Match: tgfbr1 (transforming growth factor beta receptor I [Source:NCBI gene;Acc:548715])

HSP 1 Score: 340.502 bits (872), Expect = 8.407e-109
Identity = 167/353 (47.31%), Postives = 239/353 (67.71%), Query Frame = 1
Query:  757 LPSDRDDNKDYRDNLISPFYRPFNGMKIENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            +P+D D + D       PF      +K +  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K++ S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEMK ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  154 VPNDEDPSLD------RPFISEGTTLK-DLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMLKLSLSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMKKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 490          
BLAST of activin receptor 1 vs. Ensembl Mouse
Match: Tgfbr1 (transforming growth factor, beta receptor I [Source:MGI Symbol;Acc:MGI:98728])

HSP 1 Score: 340.117 bits (871), Expect = 7.940e-110
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:   85 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 411          
BLAST of activin receptor 1 vs. Ensembl Mouse
Match: Tgfbr1 (transforming growth factor, beta receptor I [Source:MGI Symbol;Acc:MGI:98728])

HSP 1 Score: 339.347 bits (869), Expect = 2.505e-109
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:   99 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 425          
BLAST of activin receptor 1 vs. Ensembl Mouse
Match: Tgfbr1 (transforming growth factor, beta receptor I [Source:MGI Symbol;Acc:MGI:98728])

HSP 1 Score: 340.117 bits (871), Expect = 1.195e-108
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  164 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 490          
BLAST of activin receptor 1 vs. Ensembl Mouse
Match: Tgfbr1 (transforming growth factor, beta receptor I [Source:MGI Symbol;Acc:MGI:98728])

HSP 1 Score: 339.732 bits (870), Expect = 1.875e-108
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  168 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 494          
BLAST of activin receptor 1 vs. Ensembl Mouse
Match: Acvr1b (activin A receptor, type 1B [Source:MGI Symbol;Acc:MGI:1338944])

HSP 1 Score: 329.717 bits (844), Expect = 1.422e-104
Identity = 160/322 (49.69%), Postives = 221/322 (68.63%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + LS SGSG G+P+  +RT A  I L + +G+GRFG VW G+W G +VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + ++IE  +K+  S  +GLA+LH EI G  GKPGIAHRDLKS+NILVK  G C I DLGLAVR      T+D+     VGT+RYMAPE++ + I   +M +    ++FK ADIY+  LV WEI RRC    ++     Y++PY +LV +DPSIEEM+ ++CD+K+RP + + W +   L+ + K +RE W+   A+RL  +R+KK ++ 
Sbjct:  184 YDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETI---NMKH---FDSFKCADIYALGLVYWEIARRCNSGGVH---EDYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNVPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQ 496          
BLAST of activin receptor 1 vs. UniProt/SwissProt
Match: sp|Q5CD18|TGFR1_PIG (TGF-beta receptor type-1 OS=Sus scrofa OX=9823 GN=TGFBR1 PE=2 SV=1)

HSP 1 Score: 339.732 bits (870), Expect = 1.082e-107
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  168 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 494          
BLAST of activin receptor 1 vs. UniProt/SwissProt
Match: sp|P80204|TGFR1_RAT (TGF-beta receptor type-1 OS=Rattus norvegicus OX=10116 GN=Tgfbr1 PE=1 SV=1)

HSP 1 Score: 339.732 bits (870), Expect = 1.171e-107
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  166 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 492          
BLAST of activin receptor 1 vs. UniProt/SwissProt
Match: sp|Q64729|TGFR1_MOUSE (TGF-beta receptor type-1 OS=Mus musculus OX=10090 GN=Tgfbr1 PE=1 SV=1)

HSP 1 Score: 339.732 bits (870), Expect = 1.312e-107
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  168 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 494          
BLAST of activin receptor 1 vs. UniProt/SwissProt
Match: sp|P36897|TGFR1_HUMAN (TGF-beta receptor type-1 OS=Homo sapiens OX=9606 GN=TGFBR1 PE=1 SV=1)

HSP 1 Score: 339.347 bits (869), Expect = 1.413e-107
Identity = 163/336 (48.51%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  168 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 494          
BLAST of activin receptor 1 vs. UniProt/SwissProt
Match: sp|O46680|TGFR1_BOVIN (TGF-beta receptor type-1 OS=Bos taurus OX=9913 GN=TGFBR1 PE=2 SV=1)

HSP 1 Score: 338.961 bits (868), Expect = 1.880e-107
Identity = 162/336 (48.21%), Postives = 233/336 (69.35%), Query Frame = 1
Query:  817 RPF--NGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WE+ RRC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  164 RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEVARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 490          
BLAST of activin receptor 1 vs. TrEMBL
Match: L7TDS5 (Receptor protein serine/threonine kinase (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 627.091 bits (1616), Expect = 0.000e+0
Identity = 306/306 (100.00%), Postives = 306/306 (100.00%), Query Frame = 1
Query: 1111 DNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEISTLKNQITDLTSCGDFVSNDSAINDTTSYHCKSPFSNTTISTEFPSSLTSNDIIPNIVIKSKDVFSNDS 2028
            DNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEISTLKNQITDLTSCGDFVSNDSAINDTTSYHCKSPFSNTTISTEFPSSLTSNDIIPNIVIKSKDVFSNDS
Sbjct:    1 DNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEISTLKNQITDLTSCGDFVSNDSAINDTTSYHCKSPFSNTTISTEFPSSLTSNDIIPNIVIKSKDVFSNDS 306          
BLAST of activin receptor 1 vs. TrEMBL
Match: V9KQH6 (Receptor protein serine/threonine kinase (Fragment) OS=Callorhinchus milii OX=7868 PE=2 SV=1)

HSP 1 Score: 339.732 bits (870), Expect = 1.657e-107
Identity = 160/322 (49.69%), Postives = 226/322 (70.19%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPSIEEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:   13 YDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIGRRCSIGGIH---EDYQLPYYDLVPSDPSIEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 325          
BLAST of activin receptor 1 vs. TrEMBL
Match: A0A226NSR2 (Receptor protein serine/threonine kinase (Fragment) OS=Colinus virginianus OX=9014 GN=H355_015889 PE=3 SV=1)

HSP 1 Score: 341.273 bits (874), Expect = 2.371e-107
Identity = 168/356 (47.19%), Postives = 240/356 (67.42%), Query Frame = 1
Query:  757 LPSDRDDNKDYRDNLISPFYRPF--NGMKIEN-SFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            +PS+ D + D          RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEMK ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:   47 VPSEEDPSLD----------RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMKKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 383          
BLAST of activin receptor 1 vs. TrEMBL
Match: A0A226ME75 (Receptor protein serine/threonine kinase OS=Callipepla squamata OX=9009 GN=ASZ78_012112 PE=3 SV=1)

HSP 1 Score: 341.658 bits (875), Expect = 2.975e-107
Identity = 168/356 (47.19%), Postives = 240/356 (67.42%), Query Frame = 1
Query:  757 LPSDRDDNKDYRDNLISPFYRPF--NGMKIEN-SFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            +PS+ D + D          RPF   G  +++  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI RRC    ++     Y++PY +LV +DPS+EEMK ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:   65 VPSEEDPSLD----------RPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIARRCSIGGIH---EDYQLPYYDLVPSDPSVEEMKKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 401          
BLAST of activin receptor 1 vs. TrEMBL
Match: A0A3S2MHC1 (Receptor protein serine/threonine kinase OS=Oryzias javanicus OX=123683 GN=OJAV_G00201400 PE=3 SV=1)

HSP 1 Score: 338.576 bits (867), Expect = 3.851e-107
Identity = 158/322 (49.07%), Postives = 226/322 (70.19%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K++ S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI  RC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:   10 YDMTTSGSGSGLPLLVQRTIARTIILQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLSLSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIASRCSVGGIH---EDYQLPYYDLVQSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 322          
BLAST of activin receptor 1 vs. Ensembl Cavefish
Match: tgfbr1b (TGF-beta receptor type-1 [Source:NCBI gene;Acc:103034175])

HSP 1 Score: 336.65 bits (862), Expect = 1.527e-107
Identity = 164/353 (46.46%), Postives = 239/353 (67.71%), Query Frame = 1
Query:  757 LPSDRDDNKDYRDNLISPFYRPFNGMKIENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            +P++ D + D+      PF      +K +  + ++ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G+ VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +++E  +K++ S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G CCI DLGLAVR      T+D+   + VGT+RYMAPE++ D I   +M +    E+FK+ADIY+  LV WEI  RC    ++     Y++PY +LV +DPS+EEM+ ++C++K+RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  151 VPNEEDPSMDH------PFITVGTTLK-DLIYDMTTSGSGSGLPLLVQRTIARTIILQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLSLSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSI---NMKH---FESFKRADIYAMGLVFWEIASRCSIGGIH---EDYQLPYYDLVQSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 487          
BLAST of activin receptor 1 vs. Ensembl Cavefish
Match: acvr1ba (activin A receptor type 1Ba [Source:ZFIN;Acc:ZDB-GENE-980526-527])

HSP 1 Score: 331.257 bits (848), Expect = 1.918e-104
Identity = 161/322 (50.00%), Postives = 222/322 (68.94%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            F LS SGSG G+P+  +RT A  I L + +G+GRFG VW GKW G +VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + ++IE  +K++ S  +GLA+LH EI G  GKPGIAHRDLKS+NILVK  G C I DLGLAVR      T+D+     VGT+RYMAPE++ + I   +M +    ++FK ADIY+  LV WEI RRC    ++     Y++PY +LV +DPSIEEM+ ++CD+++RP + + W +   L+ + K +RE W+   A+RL  +R+KK ++ 
Sbjct:  257 FDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGKWRGGDVAVKIFSSREERSWFREAEIYQTIMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNHYSVTIEGMIKLSLSAASGLAHLHMEILGTQGKPGIAHRDLKSKNILVKKNGTCAIADLGLAVRHESVTDTIDIAPNQRVGTKRYMAPEVLDETI---NMKH---FDSFKCADIYALGLVYWEIARRCNAGGIH---EEYQLPYYDLVQSDPSIEEMRKVVCDQRLRPNVPNWWQSYEALRVMGKIMRECWYANGAARLTALRIKKTLSQ 569          
BLAST of activin receptor 1 vs. Ensembl Cavefish
Match: ACVR1C (activin A receptor type 1C [Source:NCBI gene;Acc:103026121])

HSP 1 Score: 327.405 bits (838), Expect = 4.611e-104
Identity = 155/322 (48.14%), Postives = 221/322 (68.63%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            F +S SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G++VAVKIFSSRDE SW RE +MYQ   LRH N+LGF+  D +DNG  T+LWLV++YHE+GSLF+YL  + +S++  + +  SI +GLA+LH EI G  GKP IAHRD+KS+NILVK  G   I DLGLAV+   + + +D+   + VGT+RYMAPEI+       D I     E+FK+ADIYS  LV WE+ RRC    ++     +++PY + V +DPS+E+M+ ++CD+K+RP I + W +   L+ + K +RE W+   A+RL  +R+KK ++ 
Sbjct:  174 FDMSTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEDVAVKIFSSRDERSWFREAEMYQTIMLRHENILGFIAADNKDNGSWTQLWLVSEYHEHGSLFDYLNRYTVSVDGMIVLALSIASGLAHLHMEIIGTQGKPAIAHRDIKSKNILVKKNGTAVIADLGLAVKHDSNSNAIDIPVNHRVGTKRYMAPEIL------DDTINMNSFESFKRADIYSLGLVFWELARRCSVRGIH---EDFQLPYFDQVPSDPSVEDMRRVVCDQKLRPSIPNQWQSCEALRVMGKIMRECWYANSAARLTALRVKKTLSQ 486          
BLAST of activin receptor 1 vs. Ensembl Cavefish
Match: acvr1bb (activin receptor type-1B [Source:NCBI gene;Acc:103027116])

HSP 1 Score: 326.25 bits (835), Expect = 2.599e-103
Identity = 159/322 (49.38%), Postives = 220/322 (68.32%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + LS SGSG G+P+  +RT A  I L + +G+GRFG VW GKW G +VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + ++IE  +K+  S  +GLA+LH EI G  GKPGIAHRDLKS+NILVK    C I DLGLAVR      T+D+     VGT+RYMAPE++ + I   +M +    ++FK ADIY+  LV WEI RRC    ++     Y++PY +LV +DPSIEEM+ ++CD+++RP + + W +   L+ + K +RE W+   A+RL  +R+KK ++ 
Sbjct:  189 YDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGKWRGGDVAVKIFSSREERSWFREAEIYQTIMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYSVTIEGMIKLALSAASGLAHLHMEILGTQGKPGIAHRDLKSKNILVKKNLTCAIADLGLAVRHESVTDTIDIAPNQRVGTKRYMAPEVLDESI---NMRH---FDSFKCADIYALGLVYWEIARRCNAGGIH---EEYQLPYYDLVPSDPSIEEMRKVVCDQRLRPNVPNWWQSYEALRVMGKIMRECWYANGAARLTALRIKKTLSQ 501          
BLAST of activin receptor 1 vs. Ensembl Cavefish
Match: ACVR1C (activin A receptor type 1C [Source:NCBI gene;Acc:103026121])

HSP 1 Score: 314.694 bits (805), Expect = 6.314e-101
Identity = 148/312 (47.44%), Postives = 213/312 (68.27%), Query Frame = 1
Query:  883 MPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNA 1809
            +P++ +RT A  I L +++G+GRFG VW GKW G++VAVKIFSSRDE SW RE +MYQ   LRH N+LGF+  D +DNG  T+LWLV++YHE+GSLF+YL  + +S++  + +  SI +GLA+LH EI G  GKP IAHRD+KS+NILVK  G   I DLGLAV+   + + +D+   + VGT+RYMAPEI+       D I     E+FK+ADIYS  LV WE+ RRC    ++     +++PY + V +DPS+E+M+ ++CD+K+RP I + W +   L+ + K +RE W+   A+RL  +R+KK ++  
Sbjct:   53 LPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEDVAVKIFSSRDERSWFREAEMYQTIMLRHENILGFIAADNKDNGSWTQLWLVSEYHEHGSLFDYLNRYTVSVDGMIVLALSIASGLAHLHMEIIGTQGKPAIAHRDIKSKNILVKKNGTAVIADLGLAVKHDSNSNAIDIPVNHRVGTKRYMAPEIL------DDTINMNSFESFKRADIYSLGLVFWELARRCSVRGIH---EDFQLPYFDQVPSDPSVEDMRRVVCDQKLRPSIPNQWQSCEALRVMGKIMRECWYANSAARLTALRVKKTLSQV 355          
BLAST of activin receptor 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003828.1 (pep scaffold:Pmarinus_7.0:GL476610:23057:33770:1 gene:ENSPMAG00000003465.1 transcript:ENSPMAT00000003828.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 332.798 bits (852), Expect = 1.008e-106
Identity = 162/353 (45.89%), Postives = 235/353 (66.57%), Query Frame = 1
Query:  760 PSDRDDNKDYRDNLISPFYRPFNGMKIENS-FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            P    D + YR++   P     +G  I++  ++++ SGSG G+P++ +RT A  ++L +++G+GRFG VW GKW G++VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + ++ E   +M  SI +GLA+LH EI G  GKP IAHRDLKS+NILVK  G C I DLGLAVR      T+D+   N VGT+RYMAPE++       D I     ++FK+AD+Y+  LV WEI RRC    +      Y++PY ++V +DPS+EEM+ ++CD+K+RP I + W +   L  ++K ++E W+   A+RL  +R+KK ++ 
Sbjct:  163 PVPEFDAEPYREDSFIP-----DGASIKDLLYEMTTSGSGSGLPLLVQRTIARTVALQESIGKGRFGEVWRGKWRGEDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTEEGMARMALSIASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCAIADLGLAVRHDSATDTIDIAPNNRVGTKRYMAPEVL------DDTINLKHFDSFKRADMYALGLVYWEIARRCTQGGV---LDEYQLPYYDVVPSDPSVEEMRRVVCDQKLRPSIPTRWHSCKMLHIVAKIMQECWYHNAAARLTALRVKKSLSQ 501          
BLAST of activin receptor 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007059.1 (pep scaffold:Pmarinus_7.0:GL476821:41597:91018:1 gene:ENSPMAG00000006321.1 transcript:ENSPMAT00000007059.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 325.094 bits (832), Expect = 1.301e-103
Identity = 161/325 (49.54%), Postives = 224/325 (68.92%), Query Frame = 1
Query:  844 NSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTR-RYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            N + L+ SGSG G+P++ +RT A  I L +++G+GRFG VW GKW G++VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL    + +E  +K+  S  +GLA+LH EI G  GKP IAHRDLKS+NILVK  G C I DLGLAVR      T+D+   N VGT+ RYMAPE++ D I   +M +    ++FK+ADIY+  LV WEI RRC   +  I    Y++PY ++V +DPSIEEM+ ++C++K RP I + W +   L+ ++K +RE W+   A+RL  +R+KK ++ 
Sbjct:  189 NLYDLTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRFTVPVEGMLKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGMCAIADLGLAVRHDSATDTIDIAPNNRVGTKSRYMAPEVLDDTI---NMKH---FDSFKRADIYALGLVFWEIARRCAVGA-GIHED-YQLPYYDMVPSDPSIEEMRRVVCEQKQRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ 505          
BLAST of activin receptor 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006012.1 (pep scaffold:Pmarinus_7.0:GL476493:425401:440684:1 gene:ENSPMAG00000005387.1 transcript:ENSPMAT00000006012.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 320.087 bits (819), Expect = 9.035e-102
Identity = 150/330 (45.45%), Postives = 225/330 (68.18%), Query Frame = 1
Query:  826 NGMKIENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
             G  I + +  + +GSG G+P++ +RT A  I L  ++G+GRFG VW G+W G++VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE GSLF+YL    +S+E+ VK + S+ +GLA+LH +I G  GKP IAHRD+KS+NILVK    CCI DLGLAVR      ++D+   N VGT+RYMAPE++ D I   +M +    ++FK+ DIY++ LV+WEI RRC    +      Y++PY ++VS DPS+++M+ ++C++ +RP + + W +   L+ + + +RE W+   ++RL  +R+KK ++ 
Sbjct:  177 EGTSIRDLYDNTTTGSGSGLPLLVQRTIARTIMLQDSIGKGRFGEVWRGRWRGEDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHELGSLFDYLNRFSLSVEELVKFSLSVASGLAHLHMDIVGTQGKPAIAHRDIKSKNILVKRNRTCCIADLGLAVRHDSTTDSIDIAPNNRVGTKRYMAPEVLDDTI---NMKH---FDSFKRGDIYAFGLVLWEISRRCVVGGIT---EDYQLPYHDMVSPDPSVDDMRRVVCEQSLRPNVPNRWQSSESLRVMGRVMRECWYANASARLTALRVKKSLSQ 497          
BLAST of activin receptor 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005886.1 (pep scaffold:Pmarinus_7.0:GL476493:320297:325703:1 gene:ENSPMAG00000005274.1 transcript:ENSPMAT00000005886.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 301.212 bits (770), Expect = 7.057e-97
Identity = 146/316 (46.20%), Postives = 213/316 (67.41%), Query Frame = 1
Query:  865 SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNN---VGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNIS-ASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIM 1800
            SGSG G+P + +RT A  I+LI+ VG+GR+G VW G+W G+NVAVKIFSSRDE SW RE ++Y    LRH N+LGF+ +D      +T+LWL+T YHE GSL+++L+   +     +++  S+  GL++LH EI G  GKP IAHRDLKS+NILVK  G+CCI DLGLAV   ++ S LD+     VGT R+MAPE +LD+ +Q D       +A+K+ADI++  LV+WEI RR   + L++  A  Y +P+ + V +DPS +EMK ++C  + RP I + W +   L  ++K ++E W++ P++RL  +R+KK +
Sbjct:    2 SGSGSGLPFLVQRTVARQITLIECVGKGRYGEVWRGQWQGENVAVKIFSSRDEKSWCRETEIYNTVLLRHENILGFIASDMTSRNSSTQLWLITHYHECGSLYDWLQRWPLEASSCLRLALSVAAGLSHLHGEIFGTHGKPAIAHRDLKSKNILVKGNGQCCIADLGLAVMHSQEWSRLDIGQNPRVGTVRFMAPE-VLDETLQTDC-----FDAYKRADIWALGLVLWEIARRTLSNVLSLGIAEEYRVPFHDAVPSDPSFDEMKKVVCVEQQRPNIPNRWFSDPSLTALAKLMKECWYQNPSARLTALRIKKTL 311          
BLAST of activin receptor 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005861.1 (pep scaffold:Pmarinus_7.0:GL476493:320276:325221:1 gene:ENSPMAG00000005274.1 transcript:ENSPMAT00000005861.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 299.286 bits (765), Expect = 4.100e-96
Identity = 145/315 (46.03%), Postives = 211/315 (66.98%), Query Frame = 1
Query:  865 SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNN---VGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIM 1800
            SGSG G+P + +RT A  I+LI+ VG+GR+G VW G+W G+NVAVKIFSSRDE SW RE ++Y    LRH N+LGF+ +D      +T+LWL+T YHE GSL+++L+   +     +++  S+  GL++LH EI G  GKP IAHRDLKS+NILVK  G+CCI DLGLAV   ++ S LD+     VGT R+MAPE +LD+ +Q D       +A+K+ADI++  LV+WEI RR   + +   A  Y +P+ + V +DPS +EMK ++C  + RP I + W +   L  ++K ++E W++ P++RL  +R+KK +
Sbjct:    9 SGSGSGLPFLVQRTVARQITLIECVGKGRYGEVWRGQWQGENVAVKIFSSRDEKSWCRETEIYNTVLLRHENILGFIASDMTSRNSSTQLWLITHYHECGSLYDWLQRWPLEASSCLRLALSVAAGLSHLHGEIFGTHGKPAIAHRDLKSKNILVKGNGQCCIADLGLAVMHSQEWSRLDIGQNPRVGTVRFMAPE-VLDETLQTDC-----FDAYKRADIWALGLVLWEIARRTLSNGI---AEEYRVPFHDAVPSDPSFDEMKKVVCVEQQRPNIPNRWFSDPSLTALAKLMKECWYQNPSARLTALRIKKTL 314          
BLAST of activin receptor 1 vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999])

HSP 1 Score: 76.2554 bits (186), Expect = 8.609e-15
Identity = 59/212 (27.83%), Postives = 100/212 (47.17%), Query Frame = 1
Query:  937 VGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWARE---KDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNN---VGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILR 1554
            +G+G  G V+     G NV+V I     E    +E    ++      +H N++ F+ +      L  +LW++ +Y E GSL + +   I++  Q   + R   +GL +LH++        G+ HRD+KS NIL+   G+  + D G   ++ E    L+L     VGT  +MAPE++  K   P            K DI+S  ++I E++ 
Sbjct:  626 IGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDS----YVLKGDLWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSK--------GVLHRDIKSDNILLSMEGDIKLTDFGFCAQINE----LNLKRTTMVGTPYWMAPEVVSRKEYGP------------KVDIWSLGIMIIEMIE 809          
BLAST of activin receptor 1 vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 70.8626 bits (172), Expect = 5.565e-13
Identity = 64/237 (27.00%), Postives = 115/237 (48.52%), Query Frame = 1
Query:  931 QAVGEGRFGTVWL--GKWNGDNVAVKI-----FSSRDEVSW----AREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVK-MTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILR-RCECSSLNISASAYEM 1602
            + +G+G FG V+L      G+ +AVK      +SS++E       A   ++     L H N++ ++  + ++N  +    L  +Y   GS+   +R +    E  +K +T  +  GLAYLH++        GI HRD+K+ N+L+   G C I D G++ +  +  S  D+   GT  +MAPE++  K          G  A  K DI+S   ++ E+   +   S+L + A+ +++
Sbjct: 1179 EMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYS----LFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSK--------GILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTK---------QGYSA--KVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKI 1392          
BLAST of activin receptor 1 vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144])

HSP 1 Score: 67.3958 bits (163), Expect = 5.382e-12
Identity = 55/212 (25.94%), Postives = 97/212 (45.75%), Query Frame = 1
Query:  931 QAVGEGRFGTVWLGKWN---GDNVAVKIF---SSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEI 1548
            + +G G+FG V+ G +N   G   A+K+    S  DEV   + +  +  +  + SN+  +  +  +D    T LW++ ++   GSL   LR   I  +    + R +   L  +H        K  + HRD+K+ N+L+ + G   + D G+A + +   S       GT  +MAPE+I++           G+    K DI+S  +  +EI
Sbjct:   27 EVIGRGKFGVVYKG-YNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKD----TSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIH--------KDNVIHRDIKAANVLITNEGNVKLCDFGVAAQ-VNQTSLRRQTMAGTPYWMAPEVIME-----------GVYYDTKVDIWSLGITTYEI 213          
BLAST of activin receptor 1 vs. Ensembl Yeast
Match: KCC4 (Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication [Source:SGD;Acc:S000000529])

HSP 1 Score: 66.2402 bits (160), Expect = 1.314e-11
Identity = 75/278 (26.98%), Postives = 115/278 (41.37%), Query Frame = 1
Query:  925 LIQAVGEGRFGTVWLGKWN--GDNVAVKIFS----------SRDE--VSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAH-IISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGL--EAFKKADIYSYSLVIWEILR-RCECSS---------LNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIR 1677
            L + +G G  G V L +    G   AVK+ S          S D+  + +  E+++     L H NVL        +N L    +L+ +Y E G LF  L  H  +   +A+   R I  G++Y H          GI HRDLK  N+L+ S     I D G+A  L  D   L+  + G+  Y APEI+             GL  E F  +D++S  ++++ +L  R              L +    +EMP    +S D      K ++ D + R
Sbjct:   23 LGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNL----YLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHAL--------GIVHRDLKPENLLLDSFYNIKIADFGMAA-LQTDADLLE-TSCGSPHYAAPEIV------------SGLPYEGF-ASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQR 273          
BLAST of activin receptor 1 vs. Ensembl Yeast
Match: SKM1 (Member of the PAK family of serine/threonine protein kinases; similar to Ste20p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth; SKM1 has a paralog, CLA4, that arose from the whole genome duplication [Source:SGD;Acc:S000005473])

HSP 1 Score: 65.4698 bits (158), Expect = 1.910e-11
Identity = 68/257 (26.46%), Postives = 106/257 (41.25%), Query Frame = 1
Query:  889 VMTRRTAATDI------SLIQAVGEGRFGTVWLGKW-------------------NGDNVAVK-IFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRA----------HIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEIL 1551
            +M  +T A D+       L++  G+G  G V+L K                     G+ VA+K I  S          ++   N  R  N++ F+     D+    ELW++ +Y E G L + L A            ++  Q   + +    GL +LH +         I HRD+KS NIL+ S G   I D G  V L E  S      VGT  +MAPEI+  K          G +  +K D++S  +++ E++
Sbjct:  344 IMKMKTVAIDVNPRPYFQLVEKAGQGASGAVYLSKRIKLPQENDPRFLKSHCHRVVGERVAIKQIRLSEQPKKQLIMNELLVMNDSRQENIVNFLEAYIIDD---EELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNK--------KIIHRDIKSDNILLNSQGLVKITDFGFCVELTEKRSK-RATMVGTPYWMAPEIVNQK----------GYD--EKVDVWSLGIMLIEMI 576          
BLAST of activin receptor 1 vs. Ensembl Nematostella
Match: EDO30434 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0S6])

HSP 1 Score: 309.686 bits (792), Expect = 9.973e-98
Identity = 153/321 (47.66%), Postives = 211/321 (65.73%), Query Frame = 1
Query:  865 SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNE 1818
            +GSG G+P++ +RT A  I+ I+ +G GR+G V+ G+W G++VAVKIFSSR+E SW RE  +YQ   LRH N+LGF+  D +DNG  T+LWL+TDYH NGSL++YL+   + ++  +K+T SI +GLA+LH EI G  GKP IAHRDLKSRNILVK  G CCI DLGLAV    +  TLD+   N VGTRRYMAPE + D     + + N    A+K  DIY++ LV+WEI RRC CS        Y++PY + +  DPSIEE+  ++C  K RP   + W     +  ++K ++E W   P +RL  +R+KK + + + E
Sbjct:  164 TGSGSGLPLLVQRTVARQITPIELIGSGRYGDVYRGQWRGEDVAVKIFSSREECSWFREAQIYQTVMLRHENILGFIAADNKDNGAWTQLWLITDYHANGSLYDYLQRVTLDMKSMLKLTISIASGLAHLHMEIIGTQGKPAIAHRDLKSRNILVKDNGTCCIADLGLAVCHNSEQDTLDIPYGNRVGTRRYMAPEFLEDS----NQVRN--FCAYKHGDIYAFGLVLWEITRRCICSD---KCEDYQLPYFDKICVDPSIEEVWKVVCLEKYRPSHPNYWLQDQVMMRVAKLMQECWHHSPEARLPALRIKKTLQSLYTE 475          
BLAST of activin receptor 1 vs. Ensembl Nematostella
Match: EDO41833 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S365])

HSP 1 Score: 290.041 bits (741), Expect = 9.190e-90
Identity = 144/338 (42.60%), Postives = 219/338 (64.79%), Query Frame = 1
Query:  826 NGMKIENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNN----VGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEIST 1827
            +G  +++ F  S S SG G+P++ +RT A  ++L+Q+VG+GR+G VW  +W+G++VAVKIF S  E SW RE ++YQ   LRH ++LGF+ +D   +G  T+++L+ DYH  GSL+++LR H ++ +   K+  S   G+A+LH EI G  GKP IAHRD+KS+NILVK    CCI D GLAV+ I +   +DLN     VGT+RYM+PE +L + + P+        A+K AD+YS++LV+WEI RRC      +    YE+PY + VSNDP+ EEMK ++   + RP I + W     L+ + K + E W ++PA+RL  +R+KK ++   + I++
Sbjct:  180 SGETLKDYFDQS-SASGSGLPLLVQRTIAKQVTLVQSVGKGRYGEVWKARWHGEDVAVKIFLSHCEKSWMRETEIYQTVLLRHESILGFIASDIIGSGQVTQMYLIMDYHPLGSLYDFLRGHQLNKKITGKLAFSAAAGIAHLHAEILGTQGKPMIAHRDIKSKNILVKENLTCCIADFGLAVKYIPETKGIDLNKDTNRVGTKRYMSPE-VLSQTIDPE-----SFSAYKMADMYSFALVLWEISRRCISDETGL-CEEYEVPYFDAVSNDPTFEEMKRVVVLERRRPNIPNRWFRDEMLRTMGKLMAECWSQQPAARLTALRVKKSLSKLVSAINS 509          
BLAST of activin receptor 1 vs. Ensembl Nematostella
Match: EDO49083 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI35])

HSP 1 Score: 275.018 bits (702), Expect = 9.584e-84
Identity = 136/318 (42.77%), Postives = 198/318 (62.26%), Query Frame = 1
Query:  865 SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLD---GKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNN-----VGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKK 1794
            SGSG G+P++ +RT A +  LI+++G+GR+G VW G + G++VA+KIFS+ DE SW RE ++Y    LRH N+LGF+  D       T +WL+  YHE GSL+++L       E   ++  S  +GLA+LHTEI G +    KP IAHRD+KS+NILVKS   C +GDLGLAV   +D  ++D+       VGTRRYMAPEI+       + I    + +FK+AD+Y++ LV+WEI RR     +      Y+ P+ ++V +DPSI+EMK ++     RP + + W     L+ +SK +RE W   PA+RL  +R+KK
Sbjct:  199 SGSGSGLPLLVQRTVARETQLIESIGKGRYGEVWKGVYQGESVAIKIFSTTDEASWKRETEIYNTVMLRHDNILGFIAADVHSRKSTTYMWLIMHYHEQGSLYDFLNRSTFDAETLCRLALSAASGLAHLHTEIFGTNRTGSKPAIAHRDIKSKNILVKSNYTCAVGDLGLAVMYSQDKDSVDMGENPKIAVGTRRYMAPEIL------EETINAKCINSFKRADVYAFGLVLWEIARRYVSGGI---VEEYQPPFYDMVQSDPSIDEMKKVVVTENKRPSLPNRWTGDPTLQVMSKLIRECWNPNPAARLTSLRIKK 507          
BLAST of activin receptor 1 vs. Ensembl Nematostella
Match: EDO49370 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG69])

HSP 1 Score: 202.986 bits (515), Expect = 8.113e-58
Identity = 115/307 (37.46%), Postives = 182/307 (59.28%), Query Frame = 1
Query:  919 ISLIQAVGEGRFG-TVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGF----VTTDRRDNG-LATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTE---INGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLN-NVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLN----IMRLKKI 1797
            I L++ V +G+FG TVW  K++ + VAVKIF  ++  +W  E+D Y+   L H NVL F    V  + + NG + TE WL+TD+HENGSL ++L+   + + + +++  S+ +GLAYLH++   IN    KP IAHRD+KS+NILVKS   CCI D GLA++  +     + +  VGT+RYMAPE++   I       +   E+F + D+Y+  LV+WE+L R   S  +     Y +P++  V   PS+E+M+ ++  +K+RP    SW     L+ I +++ E W ++  +RL       RLK++
Sbjct:  144 IQLLEVVSQGQFGVTVWKAKYSINTVAVKIFPHQEFTAWVNERDFYKLCGLDHENVLTFIGDEVHHESQYNGQIYTEYWLITDFHENGSLSDFLKQRSLDLAELLQLASSVCDGLAYLHSDVPAINNSSHKPCIAHRDVKSKNILVKSDLTCCISDFGLALKFDQSDKLGETHGQVGTKRYMAPEVLEGAI-------SFTRESFLRIDMYACGLVLWELLSR--FSVHDDPVEDYRLPFEQEVGLHPSLEDMQQVVVQKKMRPQFKDSWRCHAALRVIIQTIEECWDQDGEARLTSHCVAQRLKQV 441          
BLAST of activin receptor 1 vs. Ensembl Nematostella
Match: EDO41379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4E9])

HSP 1 Score: 172.94 bits (437), Expect = 1.050e-47
Identity = 100/303 (33.00%), Postives = 162/303 (53.47%), Query Frame = 1
Query:  913 TDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLD----LNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWD-NLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + ++L Q +G+GR+GTVW G    + +AVK+F +   + W  EKD++      H ++L F     R+   + E  L+++YH  GSL  YLR H +   +   M  S++ GLA+LH + N    KP  AHRD+ S+NILVK  G C + D G A+ + +     D    +  VGT RYMAPE +LD  V    I      A K+ D+Y+ SLVIWE+  RCE          Y+ P++  +    + E M + +  +K+RP    +W  N + L+ + +++ + W ++  +RL  + +K  M++
Sbjct:   95 SQLTLGQLIGQGRYGTVWKGTMFNEVMAVKVFGAEHRLFWQAEKDLFSA-LDHHPSILRFFAACERETNSSPEYLLLSEYHPRGSLQNYLRQHSVCWREMCIMGSSMSAGLAFLHQDAN----KPSFAHRDINSKNILVKVDGSCVLADFGFAMNVSDATKPADDGTLITEVGTLRYMAPE-VLDGAVNLHDIQG----ALKQIDVYAMSLVIWEVSMRCE-DIFGKQVPPYKAPFEAELGPMITSEHMHTYVVQKKLRPGFPDAWKRNHSGLRFLKETIEDCWDQDGDARLLALCIKDRMSD 386          
BLAST of activin receptor 1 vs. Ensembl Medaka
Match: ACVR1B (activin A receptor type 1B [Source:NCBI gene;Acc:101171991])

HSP 1 Score: 332.413 bits (851), Expect = 1.692e-106
Identity = 162/322 (50.31%), Postives = 221/322 (68.63%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + +S SGSG G+P+  +RT A  I L + +G+GRFG VW GKW G +VAVKIFSSR+E SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV+DYHE+GSLF+YL  + +SIE  +K+  S  +GLA+LH EI G  GKPGIAHRDLKS+NILVK  G C I DLGLAVR      T+D+     VGT+RYMAPE++ + I   +M +    ++FK ADIY+  LV WEI RRC    ++     Y++PY +LV +DPSIEEM+ ++CD+K+RP I + W +   L+ + K +RE W+   A+RL  +R+KK ++ 
Sbjct:  135 YDMSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGKWRGGDVAVKIFSSREERSWFREAEIYQTIMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYSVSIESMIKLALSAASGLAHLHMEILGTQGKPGIAHRDLKSKNILVKKNGTCAIADLGLAVRHESITDTIDIAPNQRVGTKRYMAPEVLDETI---NMKH---FDSFKCADIYALGLVYWEIARRCNAGGIH---DEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPSIPNWWQSYESLRVMGKIMRECWYANGAARLTALRIKKTLSQ 447          
BLAST of activin receptor 1 vs. Ensembl Medaka
Match: ACVR1C (activin A receptor type 1C [Source:NCBI gene;Acc:101173751])

HSP 1 Score: 323.168 bits (827), Expect = 4.797e-103
Identity = 152/322 (47.20%), Postives = 222/322 (68.94%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + +S SGSG G+P++ +RT A  I L + +G+GR+G VW GKW G++VAVKIFSSRDE SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV++YHE+GSL++YL  + +S+E  V +  S+ +GLA+LH EI G  GKP IAHRDLKS+N+LV+  G   I DLGLAV+   + +T+D+   + VGT+RYMAPEI+       + I     E+FK+ADIYS  LV WE+ RRC    L+     +++PY ++V +DPSIE+M+ ++CD+K+RP I + W +   L+ + K +RE W+   ++RL  +R+KK ++ 
Sbjct:  123 YDMSTSGSGSGLPLLVQRTIARTIVLQETIGKGRYGEVWRGKWRGEDVAVKIFSSRDERSWFREAEIYQTIMLRHENILGFIAADNKDNGSWTQLWLVSEYHEHGSLYDYLNRYTVSVEGMVVLALSVASGLAHLHMEIIGTQGKPAIAHRDLKSKNVLVRKNGTAVIADLGLAVKHDSNTNTIDIPSNHRVGTKRYMAPEIL------DESINMNTFESFKRADIYSLGLVFWELARRCSVRGLH---EDFQLPYYDMVPSDPSIEDMRKVVCDQKLRPNIPNQWQSCEALRVMGKLMRECWYANSSARLTALRVKKTVSQ 435          
BLAST of activin receptor 1 vs. Ensembl Medaka
Match: ACVR1C (activin A receptor type 1C [Source:NCBI gene;Acc:101173751])

HSP 1 Score: 323.168 bits (827), Expect = 4.797e-103
Identity = 152/322 (47.20%), Postives = 222/322 (68.94%), Query Frame = 1
Query:  850 FQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            + +S SGSG G+P++ +RT A  I L + +G+GR+G VW GKW G++VAVKIFSSRDE SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV++YHE+GSL++YL  + +S+E  V +  S+ +GLA+LH EI G  GKP IAHRDLKS+N+LV+  G   I DLGLAV+   + +T+D+   + VGT+RYMAPEI+       + I     E+FK+ADIYS  LV WE+ RRC    L+     +++PY ++V +DPSIE+M+ ++CD+K+RP I + W +   L+ + K +RE W+   ++RL  +R+KK ++ 
Sbjct:  123 YDMSTSGSGSGLPLLVQRTIARTIVLQETIGKGRYGEVWRGKWRGEDVAVKIFSSRDERSWFREAEIYQTIMLRHENILGFIAADNKDNGSWTQLWLVSEYHEHGSLYDYLNRYTVSVEGMVVLALSVASGLAHLHMEIIGTQGKPAIAHRDLKSKNVLVRKNGTAVIADLGLAVKHDSNTNTIDIPSNHRVGTKRYMAPEIL------DESINMNTFESFKRADIYSLGLVFWELARRCSVRGLH---EDFQLPYYDMVPSDPSIEDMRKVVCDQKLRPNIPNQWQSCEALRVMGKLMRECWYANSSARLTALRVKKTVSQ 435          
BLAST of activin receptor 1 vs. Ensembl Medaka
Match: ACVR1C (activin A receptor type 1C [Source:NCBI gene;Acc:101173751])

HSP 1 Score: 314.309 bits (804), Expect = 9.515e-101
Identity = 147/312 (47.12%), Postives = 215/312 (68.91%), Query Frame = 1
Query:  880 GMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDL---NNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNN 1806
            G+P++ +RT A  I L + +G+GR+G VW GKW G++VAVKIFSSRDE SW RE ++YQ   LRH N+LGF+  D +DNG  T+LWLV++YHE+GSL++YL  + +S+E  V +  S+ +GLA+LH EI G  GKP IAHRDLKS+N+LV+  G   I DLGLAV+   + +T+D+   + VGT+RYMAPEI+       + I     E+FK+ADIYS  LV WE+ RRC    L+     +++PY ++V +DPSIE+M+ ++CD+K+RP I + W +   L+ + K +RE W+   ++RL  +R+KK ++ 
Sbjct:   52 GLPLLVQRTIARTIVLQETIGKGRYGEVWRGKWRGEDVAVKIFSSRDERSWFREAEIYQTIMLRHENILGFIAADNKDNGSWTQLWLVSEYHEHGSLYDYLNRYTVSVEGMVVLALSVASGLAHLHMEIIGTQGKPAIAHRDLKSKNVLVRKNGTAVIADLGLAVKHDSNTNTIDIPSNHRVGTKRYMAPEIL------DESINMNTFESFKRADIYSLGLVFWELARRCSVRGLH---EDFQLPYYDMVPSDPSIEDMRKVVCDQKLRPNIPNQWQSCEALRVMGKLMRECWYANSSARLTALRVKKTVSQ 354          
BLAST of activin receptor 1 vs. Ensembl Medaka
Match: ENSORLT00000020918.2 (activin A receptor type 1 [Source:NCBI gene;Acc:101173900])

HSP 1 Score: 306.22 bits (783), Expect = 8.906e-96
Identity = 151/332 (45.48%), Postives = 218/332 (65.66%), Query Frame = 1
Query:  859 SC-SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNN---VGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEISTLKNQI 1842
            SC SGSG G+P + +RT A  I+L + VG+GR+G VW G+W G++VAVKIFSSRDE SW RE ++Y    LRH N+LGF+ +D      +T+LWL+T +HE GSL++YL+   +     ++M  SI +GLA+LH EI G  GKP IAHRDLKS+NILVK  G+CCI DLGLAV   +D + LD+ N   VGT+RYMAPE +LD  +Q D       E++K+ DI++  LV+WEI RR   + +      Y+ P+ ++V +DPS E+MK ++C  + RP I + W +   L  ++K ++E W++ P++RL  +R+KK +    N +  +K  I
Sbjct:  179 SCTSGSGSGLPFLVQRTVARQITLNECVGKGRYGEVWRGQWQGESVAVKIFSSRDEKSWFRETEIYNTVLLRHENILGFIASDMTSRNSSTQLWLITHFHEMGSLYDYLQLSTLDAPGCLRMALSIASGLAHLHVEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHFQDTNELDVGNNPKVGTKRYMAPE-VLDDSIQMD-----SFESYKRVDIWALGLVLWEIARRTVSNGI---VEDYKPPFHDVVPSDPSFEDMKKVVCVDQQRPNIPNRWFSDLTLTSMAKLMKECWYQNPSARLTALRIKKTLTKIDNSLDKIKTDI 501          
BLAST of activin receptor 1 vs. Planmine SMEST
Match: SMESG000006023.1 (SMESG000006023.1)

HSP 1 Score: 1313.13 bits (3397), Expect = 0.000e+0
Identity = 662/662 (100.00%), Postives = 662/662 (100.00%), Query Frame = 1
Query:   70 MKIYESIECIDFQCFDGGHERNNNCFPCTNVSFIARKHWLNHLENMILIHRKLKNTELALQVEVKISQGMYCCNFDQNVGKIETCSLNFSPGSKDGIPHYGMGCDGRNFWLQSTCLNAKVESRCCRSNHCNYPDSDDLKHMMDQAGIIFPRVVETGNPKIVIVCMXXXXXXXXXXXXXXXXFKVARRKYLSKKYPQTTDLPHHSFYHKLLCFNKLXXXXXXXXXXXXCNLPSDRDDNKDYRDNLISPFYRPFNGMKIENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEISTLKNQITDLTSCGDFVSNDSAINDTTSYHCKSPFSNTTISTEFPSSLTSNDIIPNIVIKSKDVFSNDSYCLGVMNQM 2055
            MKIYESIECIDFQCFDGGHERNNNCFPCTNVSFIARKHWLNHLENMILIHRKLKNTELALQVEVKISQGMYCCNFDQNVGKIETCSLNFSPGSKDGIPHYGMGCDGRNFWLQSTCLNAKVESRCCRSNHCNYPDSDDLKHMMDQAGIIFPRVVETGNPKIVIVCMALLIGVSVVVIIAIVSFKVARRKYLSKKYPQTTDLPHHSFYHKLLCFNKLFSIVRSFRRRSSCNLPSDRDDNKDYRDNLISPFYRPFNGMKIENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEISTLKNQITDLTSCGDFVSNDSAINDTTSYHCKSPFSNTTISTEFPSSLTSNDIIPNIVIKSKDVFSNDSYCLGVMNQM
Sbjct:    1 MKIYESIECIDFQCFDGGHERNNNCFPCTNVSFIARKHWLNHLENMILIHRKLKNTELALQVEVKISQGMYCCNFDQNVGKIETCSLNFSPGSKDGIPHYGMGCDGRNFWLQSTCLNAKVESRCCRSNHCNYPDSDDLKHMMDQAGIIFPRVVETGNPKIVIVCMALLIGVSVVVIIAIVSFKVARRKYLSKKYPQTTDLPHHSFYHKLLCFNKLFSIVRSFRRRSSCNLPSDRDDNKDYRDNLISPFYRPFNGMKIENSFQLSCSGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEISTLKNQITDLTSCGDFVSNDSAINDTTSYHCKSPFSNTTISTEFPSSLTSNDIIPNIVIKSKDVFSNDSYCLGVMNQM 662          
BLAST of activin receptor 1 vs. Planmine SMEST
Match: SMESG000019732.1 (SMESG000019732.1)

HSP 1 Score: 263.462 bits (672), Expect = 3.972e-79
Identity = 145/340 (42.65%), Postives = 199/340 (58.53%), Query Frame = 1
Query:  865 SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTE-INGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTL------DLNNVGTRRYMAPEIILDKIVQPDMIYNGG-----------------------LEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKK 1794
            SGSG GMP + +RT A  + LI  +G+GRFG VW G + G+ VAVKIFSSRDE SWARE  +Y    LRH N+LG+  +D       T+LWL+T YH  GSL++YL + +IS  + V +  S   GL++LHTE I+G  GKP IAHRDLKS+NIL+   GE CI DLGL+V L    + L        + +GTRRYMAPEI+ D +  PD  +                           E F  ADIY+++LV+WE+L R   S    +   Y++PYQ++V  DPS  EM+ ++C  K RP +  S      + +++  +RESW E+  +R + +RLKK
Sbjct:  202 SGSGSGMPFLVQRTIARQVQLINGIGKGRFGEVWKGAYYGEMVAVKIFSSRDETSWARETHIYNTYLLRHPNILGYYASDMVSRFGCTQLWLITHYHALGSLYDYLHSTVISFNECVSLLHSTAAGLSHLHTEIISGPQGKPSIAHRDLKSKNILIIKPGEACIADLGLSV-LQSSTNCLCPSPVNSKHKIGTRRYMAPEILADCLC-PDTDFTIENCLADPTSPSIATVTQHEACPIRFEHFISADIYAFALVMWEVLTRTFLSGQK-TIMEYKVPYQDIVPLDPSTPEMRQLVCVDKFRPELPDSKSVF--VLELNAMIRESWSEKSQTRPSALRLKK 536          
BLAST of activin receptor 1 vs. Planmine SMEST
Match: SMESG000068827.1 (SMESG000068827.1)

HSP 1 Score: 263.848 bits (673), Expect = 1.310e-78
Identity = 149/365 (40.82%), Postives = 214/365 (58.63%), Query Frame = 1
Query:  829 GMKIENSFQLSC-SGSGFGMPVMTRRTAATDISLIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAV--RLIEDCSTLDLNN----VGTRRYMAPEI-------------------ILDKIVQPDMIYN----GGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWD-NLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEISTL 1830
            G+ +E     +C SGSG G+P + +RT A  I+L++ +G+G+FG VW G++ G+ VAVKIFSSR+E SW RE ++Y    LRH N+LG+  +D   N   T+LW+V  YH  GSL EYL A+ +++   +K+  S   GL +LHT I GL GKP IAHRD+KS+NILVK    CCI DLGLAV    + +   L  NN    VGT+RYMAPE+                   I   I     I N      +E+ K AD+YSYSLV+WEIL R   ++ +     Y++P+   V +DPS EEM  ++ ++ +RP ++ +    LNP   + K + E W + P+ RL+++R+KK + N   + S L
Sbjct:  226 GVTLEKLRDDTCTSGSGSGLPFLVQRTVARQINLLECIGKGKFGEVWKGQFQGELVAVKIFSSREESSWTRETNIYNTVLLRHDNILGYYASDLISNSGCTQLWMVMQYHPLGSLHEYLSANTLTVSTVLKLAHSAAAGLCHLHTRIMGLQGKPAIAHRDVKSKNILVKKNLTCCIADLGLAVFPESMGNNEQLSENNNNRIVGTKRYMAPELLELACFLSNNQSENFNSNNIHLNISSTSSIMNIHGENYMESLKAADVYSYSLVLWEILSR---TTFDGVIQPYQLPFGENVQSDPSFEEMFKVVVEQGLRPNLSENIKAQLNP---VVKIMEECWHQRPSIRLSMLRVKKSLFNIVMKYSNL 584          
BLAST of activin receptor 1 vs. Planmine SMEST
Match: SMESG000070956.1 (SMESG000070956.1)

HSP 1 Score: 176.407 bits (446), Expect = 4.151e-47
Identity = 112/305 (36.72%), Postives = 169/305 (55.41%), Query Frame = 1
Query:  931 QAVGEGRFGTVWLGKWNGDN------VAVKIFSSRDE--VSWAREKDMYQ--QNFLRHSNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMTRSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWN 1815
            Q + +GRFG VW G     N      VA+KIFS   E   SW  E  +Y   QN   H N+L +   +RR     TELWLV +Y+  GSL+ YL+   ++    +++ ++I  GLA+LH+    ++    IAHRD+KS+NIL+K     CI D GLA+      ++ + N VGT  YMAPEI+   I       N  + +F K DI+S SLV WE+L R + S L+I    ++ P+Q +V  +PS E+++  +  +K+RP  N +W NL  +    K++ E W E+P +RL+   + + MN+  N
Sbjct:  275 QLLAQGRFGQVWSGIIETRNEHKKQIVAIKIFSDNKEGKKSWRNESTVYSILQNG-PHPNILKYFGAERRMKDSITELWLVVEYYPLGSLWNYLKKSTVTWSDLLQICQNIAAGLAHLHSFSKPINSP--IAHRDIKSKNILLKENYTACIADFGLAICHQNTDNSFN-NRVGTLSYMAPEILEGSI-------NFDIYSFLKIDIFSMSLVFWEVLSRFQFSDLHIKD--FQNPFQEIVGENPSFEQLRQCVTIKKLRPAFNENWINLPDVIKFWKTITECWDEDPDARLSAECVLERMNDLCN 566          
BLAST of activin receptor 1 vs. Planmine SMEST
Match: SMESG000060769.1 (SMESG000060769.1)

HSP 1 Score: 160.229 bits (404), Expect = 7.256e-42
Identity = 104/301 (34.55%), Postives = 159/301 (52.82%), Query Frame = 1
Query:  946 GRFGTVWLGKWNGD-------NVAVKIFSSRDEVSWAREKDMYQQNFLRHSNVLGFVTTDR-RDNGLATELWLVTDYHENGSLFEYLRAHIISIE---QAVKMTRSITNGLAYLHTEIN-----GLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAVRLIEDCSTLDLN-NVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYSYSLVIWEILRRC-------ECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKIRPPINSSWDNLNPLKDISKSVRESWFEEPASRLN 1776
            G+FG +W GK   D       NVA+KI   RDE SW  E DMY+    R S +L ++  D+   N    E WLVT Y E GSL++ L   + +     Q + +   I  GL+YLH + +      + GKP IAHRDLKSRNIL+K+  + CI DLGLAV    + S  DL+  VGT+RYMAPE++   I       N   ++F   DIY+ +L++WE+  +C       EC +     S Y  P++  +    ++E ++S + +   RP + S +   +  + + +++ E W  +  +RL+
Sbjct:  188 GKFGEIWSGKLISDHSNGAIGNVAIKILRPRDESSWETEIDMYRYIRNRCSRILRYIGCDKIVTNNEIEEFWLVTQYIEYGSLYDCLSDSVRTKPNWFQVLNVCLDIAGGLSYLHEDGSYQTSAHISGKPSIAHRDLKSRNILIKADWKACIADLGLAVSFQGNRSLSDLHLQVGTQRYMAPEVLEGAI-------NFSRDSFLGIDIYAMALIMWEVFSQCTDFQGLAECEA--SEPSVYMQPFEQELGIHITMESLQSWVVNDNKRPQLPSQYSGFSDGQSLWRTIVECWDRDAEARLS 479          
The following BLAST results are available for this feature:
BLAST of activin receptor 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TGFBR13.849e-10948.51transforming growth factor beta receptor 1 [Source... [more]
TGFBR12.943e-10848.51transforming growth factor beta receptor 1 [Source... [more]
TGFBR13.212e-10848.51transforming growth factor beta receptor 1 [Source... [more]
TGFBR11.122e-10549.68transforming growth factor beta receptor 1 [Source... [more]
ACVR1B2.095e-10550.00activin A receptor type 1B [Source:HGNC Symbol;Acc... [more]
back to top
BLAST of activin receptor 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sma-65.439e-6737.20Serine/threonine-protein kinase sma-6 [Source:Uni... [more]
daf-13.622e-6638.87Cell surface receptor daf-1 [Source:UniProtKB/Swi... [more]
daf-15.657e-6538.36Cell surface receptor daf-1 [Source:UniProtKB/Swi... [more]
daf-41.013e-3629.30Cell surface receptor daf-4 [Source:UniProtKB/Swi... [more]
daf-42.785e-3629.30Cell surface receptor daf-4 [Source:UniProtKB/Swi... [more]
back to top
BLAST of activin receptor 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
babo1.408e-10247.08gene:FBgn0011300 transcript:FBtr0088659[more]
babo1.464e-10246.87gene:FBgn0011300 transcript:FBtr0300599[more]
babo5.577e-10247.08gene:FBgn0011300 transcript:FBtr0088658[more]
tkv5.350e-8943.26gene:FBgn0003716 transcript:FBtr0079089[more]
tkv9.531e-8943.26gene:FBgn0003716 transcript:FBtr0079088[more]
back to top
BLAST of activin receptor 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tgfbr1a5.471e-10846.74transforming growth factor, beta receptor 1 a [Sou... [more]
tgfbr1b1.749e-10746.46transforming growth factor, beta receptor 1 b [Sou... [more]
acvr1ba1.530e-10449.69activin A receptor type 1Ba [Source:ZFIN;Acc:ZDB-G... [more]
acvr1bb1.677e-10450.00activin A receptor type 1Bb [Source:ZFIN;Acc:ZDB-G... [more]
acvr1bb2.511e-10450.00activin A receptor type 1Bb [Source:ZFIN;Acc:ZDB-G... [more]
back to top
BLAST of activin receptor 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tgfbr13.997e-10947.19transforming growth factor beta receptor I [Source... [more]
tgfbr14.401e-10947.19transforming growth factor beta receptor I [Source... [more]
tgfbr17.506e-10947.31transforming growth factor beta receptor I [Source... [more]
tgfbr17.772e-10947.19transforming growth factor beta receptor I [Source... [more]
tgfbr18.407e-10947.31transforming growth factor beta receptor I [Source... [more]
back to top
BLAST of activin receptor 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tgfbr17.940e-11048.51transforming growth factor, beta receptor I [Sourc... [more]
Tgfbr12.505e-10948.51transforming growth factor, beta receptor I [Sourc... [more]
Tgfbr11.195e-10848.51transforming growth factor, beta receptor I [Sourc... [more]
Tgfbr11.875e-10848.51transforming growth factor, beta receptor I [Sourc... [more]
Acvr1b1.422e-10449.69activin A receptor, type 1B [Source:MGI Symbol;Acc... [more]
back to top
BLAST of activin receptor 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5CD18|TGFR1_PIG1.082e-10748.51TGF-beta receptor type-1 OS=Sus scrofa OX=9823 GN=... [more]
sp|P80204|TGFR1_RAT1.171e-10748.51TGF-beta receptor type-1 OS=Rattus norvegicus OX=1... [more]
sp|Q64729|TGFR1_MOUSE1.312e-10748.51TGF-beta receptor type-1 OS=Mus musculus OX=10090 ... [more]
sp|P36897|TGFR1_HUMAN1.413e-10748.51TGF-beta receptor type-1 OS=Homo sapiens OX=9606 G... [more]
sp|O46680|TGFR1_BOVIN1.880e-10748.21TGF-beta receptor type-1 OS=Bos taurus OX=9913 GN=... [more]
back to top
BLAST of activin receptor 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
L7TDS50.000e+0100.00Receptor protein serine/threonine kinase (Fragment... [more]
V9KQH61.657e-10749.69Receptor protein serine/threonine kinase (Fragment... [more]
A0A226NSR22.371e-10747.19Receptor protein serine/threonine kinase (Fragment... [more]
A0A226ME752.975e-10747.19Receptor protein serine/threonine kinase OS=Callip... [more]
A0A3S2MHC13.851e-10749.07Receptor protein serine/threonine kinase OS=Oryzia... [more]
back to top
BLAST of activin receptor 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tgfbr1b1.527e-10746.46TGF-beta receptor type-1 [Source:NCBI gene;Acc:103... [more]
acvr1ba1.918e-10450.00activin A receptor type 1Ba [Source:ZFIN;Acc:ZDB-G... [more]
ACVR1C4.611e-10448.14activin A receptor type 1C [Source:NCBI gene;Acc:1... [more]
acvr1bb2.599e-10349.38activin receptor type-1B [Source:NCBI gene;Acc:103... [more]
ACVR1C6.314e-10147.44activin A receptor type 1C [Source:NCBI gene;Acc:1... [more]
back to top
BLAST of activin receptor 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000003828.11.008e-10645.89pep scaffold:Pmarinus_7.0:GL476610:23057:33770:1 g... [more]
ENSPMAT00000007059.11.301e-10349.54pep scaffold:Pmarinus_7.0:GL476821:41597:91018:1 g... [more]
ENSPMAT00000006012.19.035e-10245.45pep scaffold:Pmarinus_7.0:GL476493:425401:440684:1... [more]
ENSPMAT00000005886.17.057e-9746.20pep scaffold:Pmarinus_7.0:GL476493:320297:325703:1... [more]
ENSPMAT00000005861.14.100e-9646.03pep scaffold:Pmarinus_7.0:GL476493:320276:325221:1... [more]
back to top
BLAST of activin receptor 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
STE208.609e-1527.83Cdc42p-activated signal transducing kinase; involv... [more]
BCK15.565e-1327.00MAPKKK acting in the protein kinase C signaling pa... [more]
KIC15.382e-1225.94Protein kinase of the PAK/Ste20 family, required f... [more]
KCC41.314e-1126.98Protein kinase of the bud neck involved in the sep... [more]
SKM11.910e-1126.46Member of the PAK family of serine/threonine prote... [more]
back to top
BLAST of activin receptor 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO304349.973e-9847.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO418339.190e-9042.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO490839.584e-8442.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO493708.113e-5837.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO413791.050e-4733.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of activin receptor 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ACVR1B1.692e-10650.31activin A receptor type 1B [Source:NCBI gene;Acc:1... [more]
ACVR1C4.797e-10347.20activin A receptor type 1C [Source:NCBI gene;Acc:1... [more]
ACVR1C4.797e-10347.20activin A receptor type 1C [Source:NCBI gene;Acc:1... [more]
ACVR1C9.515e-10147.12activin A receptor type 1C [Source:NCBI gene;Acc:1... [more]
ENSORLT00000020918.28.906e-9645.48activin A receptor type 1 [Source:NCBI gene;Acc:10... [more]
back to top
BLAST of activin receptor 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000006023.10.000e+0100.00SMESG000006023.1[more]
SMESG000019732.13.972e-7942.65SMESG000019732.1[more]
SMESG000068827.11.310e-7840.82SMESG000068827.1[more]
SMESG000070956.14.151e-4736.72SMESG000070956.1[more]
SMESG000060769.17.256e-4234.55SMESG000060769.1[more]
back to top
Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30023675
GenBankAGC30582.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023675 ID=SMED30023675|Name=activin receptor 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2128bp
TCATTTTCAATATAAATTTATTAAATGTTCTTTAAATGTTTTATTTACTT
ATTTTTGTATTGTAACCTTATGAAGATCTATGAATCCATTGAATGCATTG
ATTTCCAGTGTTTCGATGGAGGGCACGAAAGAAATAATAATTGTTTTCCT
TGTACAAATGTTTCTTTCATTGCTCGCAAGCACTGGTTAAATCATTTGGA
AAATATGATTTTAATTCACCGAAAATTAAAGAATACTGAGTTAGCATTAC
AGGTCGAAGTAAAAATTTCTCAAGGCATGTACTGTTGTAACTTTGATCAA
AATGTTGGAAAAATCGAAACATGTTCTTTAAATTTCTCTCCTGGTAGTAA
AGATGGAATTCCACATTATGGAATGGGATGTGATGGAAGGAATTTCTGGC
TACAATCTACTTGTTTAAACGCAAAAGTTGAATCTCGATGTTGCCGTTCA
AATCATTGCAACTATCCAGATTCAGATGACTTGAAGCATATGATGGATCA
AGCAGGTATAATTTTTCCAAGGGTTGTGGAAACTGGAAATCCAAAAATTG
TCATAGTTTGTATGGCTTTGCTAATTGGAGTTTCCGTTGTAGTTATTATA
GCTATAGTATCCTTCAAAGTTGCAAGAAGAAAATATTTATCCAAAAAATA
TCCACAAACCACAGACTTGCCACATCATTCATTTTACCACAAATTACTGT
GCTTTAATAAGTTATTTTCGATTGTCCGAAGTTTCAGGCGACGATCAAGT
TGTAACCTTCCTTCAGATCGAGACGATAACAAAGATTATAGAGACAATCT
TATTAGTCCATTTTACAGGCCATTTAATGGCATGAAAATTGAAAATAGTT
TTCAATTATCTTGTAGTGGCTCAGGATTTGGAATGCCTGTTATGACGAGA
AGAACTGCTGCAACAGATATCAGTCTGATTCAGGCGGTTGGTGAAGGTCG
ATTTGGCACTGTGTGGTTGGGAAAATGGAATGGAGACAATGTCGCTGTAA
AAATATTTAGTAGTCGCGATGAAGTGTCATGGGCTCGGGAAAAAGACATG
TATCAACAAAACTTCTTGCGACACTCTAACGTATTGGGCTTTGTAACTAC
TGATAGACGGGATAATGGACTTGCTACAGAATTATGGCTAGTAACAGATT
ATCATGAAAACGGATCATTGTTTGAGTACCTACGTGCACATATTATCTCT
ATTGAACAAGCAGTTAAAATGACTCGATCAATTACCAATGGATTGGCATA
TTTGCACACTGAAATAAATGGATTAGACGGTAAACCTGGAATCGCTCATC
GGGATCTCAAAAGTCGCAACATTCTTGTTAAATCTTGTGGAGAATGTTGT
ATTGGAGATTTGGGATTGGCTGTTCGACTTATTGAGGATTGTTCCACTTT
GGATTTAAATAATGTTGGTACAAGGCGATACATGGCACCTGAGATAATTT
TGGATAAAATCGTTCAACCTGACATGATTTACAACGGTGGTCTTGAAGCA
TTTAAAAAGGCCGACATATACAGTTATAGTTTGGTCATTTGGGAAATTTT
ACGGCGTTGTGAATGTTCTTCTCTGAATATCAGCGCATCTGCATATGAGA
TGCCATATCAAAATTTGGTTAGCAATGATCCAAGCATTGAAGAAATGAAG
TCGATTATTTGTGACAGAAAAATTCGTCCTCCAATTAATTCTAGCTGGGA
TAATTTAAATCCACTGAAAGATATTTCGAAATCTGTTCGTGAATCTTGGT
TTGAAGAGCCAGCCTCGAGATTGAATATAATGCGTCTTAAAAAAATAATG
AATAACGCCTGGAATGAAATCAGCACACTGAAAAACCAAATTACCGATTT
AACATCCTGCGGGGATTTTGTGTCAAATGACAGCGCGATAAACGATACAA
CAAGCTACCATTGCAAATCTCCATTCAGTAATACAACAATCTCCACTGAA
TTTCCTTCAAGCTTGACTAGTAACGATATTATTCCAAATATCGTCATCAA
ATCTAAAGACGTCTTTTCTAATGATTCATATTGTCTGGGAGTTATGAACC
AAATGTAATCCTGATGCATTCATAATTGTATAAAATTTATTTGAAATTGT
GTACTATTATTTTCTATCATTTGTATAG
back to top

protein sequence of SMED30023675-orf-1

>SMED30023675-orf-1 ID=SMED30023675-orf-1|Name=SMED30023675-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=678bp
MFFKCFIYLFLYCNLMKIYESIECIDFQCFDGGHERNNNCFPCTNVSFIA
RKHWLNHLENMILIHRKLKNTELALQVEVKISQGMYCCNFDQNVGKIETC
SLNFSPGSKDGIPHYGMGCDGRNFWLQSTCLNAKVESRCCRSNHCNYPDS
DDLKHMMDQAGIIFPRVVETGNPKIVIVCMALLIGVSVVVIIAIVSFKVA
RRKYLSKKYPQTTDLPHHSFYHKLLCFNKLFSIVRSFRRRSSCNLPSDRD
DNKDYRDNLISPFYRPFNGMKIENSFQLSCSGSGFGMPVMTRRTAATDIS
LIQAVGEGRFGTVWLGKWNGDNVAVKIFSSRDEVSWAREKDMYQQNFLRH
SNVLGFVTTDRRDNGLATELWLVTDYHENGSLFEYLRAHIISIEQAVKMT
RSITNGLAYLHTEINGLDGKPGIAHRDLKSRNILVKSCGECCIGDLGLAV
RLIEDCSTLDLNNVGTRRYMAPEIILDKIVQPDMIYNGGLEAFKKADIYS
YSLVIWEILRRCECSSLNISASAYEMPYQNLVSNDPSIEEMKSIICDRKI
RPPINSSWDNLNPLKDISKSVRESWFEEPASRLNIMRLKKIMNNAWNEIS
TLKNQITDLTSCGDFVSNDSAINDTTSYHCKSPFSNTTISTEFPSSLTSN
DIIPNIVIKSKDVFSNDSYCLGVMNQM*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004675transmembrane receptor protein serine/threonine kinase activity
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0004702signal transducer, downstream of receptor, with serine/threonine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR000333TGFB_receptor
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0016310phosphorylation
GO:0023014signal transduction by protein phosphorylation
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 299..597
e-value: 3.2E-20
score: 83.2
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 302..530
e-value: 6.6E-32
score: 110.9
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 299..597
score: 35.538
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 268..378
e-value: 2.8E-37
score: 129.3
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 379..598
e-value: 3.9E-47
score: 162.5
NoneNo IPR availablePANTHERPTHR23255:SF71RECEPTOR PROTEIN SERINE/THREONINE KINASEcoord: 131..595
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.531
NoneNo IPR availableTMHMMTMhelixcoord: 175..197
IPR000333Ser/Thr protein kinase, TGFB receptorPANTHERPTHR23255TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND IIcoord: 131..595
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 305..326
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 423..435
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 280..590