Cathepsin L2

Overview
NameCathepsin L2
Smed IDSMED30023605
Length (bp)1230
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cathepsin L2 (SMED30023605) t-SNE clustered cells

Violin plots show distribution of expression levels for Cathepsin L2 (SMED30023605) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cathepsin L2 (SMED30023605) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cathepsin L2 (SMED30023605) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023605

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30023605SMESG000049716.1 dd_Smed_v4_582_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023605SMESG000049716.1 dd_Smed_v4_582_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023605SMESG000049716.1 Contig44524newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023605SMESG000049716.1 Contig44524uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
parenchymaSMED30023605SMESG000049716.1 dd_582dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult fluorescence in situ hybridization evidence
body wall musculatureSMED30023605SMESG000049716.1 dd_Smed_v4_582_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023605SMESG000049716.1 dd_Smed_v6_582_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
glial cellSMED30023605SMESG000049716.1 dd_Smed_v6_582_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Category 2 cellSMED30023605SMESG000049716.1 dd_Smed_v4_582_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538])

HSP 1 Score: 328.176 bits (840), Expect = 3.527e-110
Identity = 163/339 (48.08%), Postives = 218/339 (64.31%), Query Frame = 1 
Query:   73 MHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            M+   ++       A  +P    F Q  D  W ++K    ++Y    E  RR +WE+N++ I+ HN EY+ G+H +T+ +N F D++++EF  +   +R   +   +    ++   L LP SV+W KKGYVTPVKNQ QCGSCWAFS TG++EGQ F+KT KLVS SEQ LVDCS+  GN+GCNGGFM +AFQY+ +  G++ E  YPY A+D  C+Y     +     +T +  G E+ L + +ATVGPISV +DA + SFQ Y  GIY E  CSS  LDHGVL VGYG +    +  KYWLVKNSWG  WG NGY+K++KDKNN CGIAT ASYPN+
Sbjct:    1 MNLSLVLAAFCLGIASAVP---KFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRN--QKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
[Close]
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538])

HSP 1 Score: 328.176 bits (840), Expect = 3.527e-110
Identity = 163/339 (48.08%), Postives = 218/339 (64.31%), Query Frame = 1 
Query:   73 MHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            M+   ++       A  +P    F Q  D  W ++K    ++Y    E  RR +WE+N++ I+ HN EY+ G+H +T+ +N F D++++EF  +   +R   +   +    ++   L LP SV+W KKGYVTPVKNQ QCGSCWAFS TG++EGQ F+KT KLVS SEQ LVDCS+  GN+GCNGGFM +AFQY+ +  G++ E  YPY A+D  C+Y     +     +T +  G E+ L + +ATVGPISV +DA + SFQ Y  GIY E  CSS  LDHGVL VGYG +    +  KYWLVKNSWG  WG NGY+K++KDKNN CGIAT ASYPN+
Sbjct:    1 MNLSLVLAAFCLGIASAVP---KFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRN--QKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
[Close]
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537])

HSP 1 Score: 308.916 bits (790), Expect = 1.391e-102
Identity = 156/332 (46.99%), Postives = 215/332 (64.76%), Query Frame = 1 
Query:   97 LIVPCFAETIPWSGIFF-QGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            LI+  F   I  + + F    +  W+++K   N++Y    E  RR +WE+N++ I+ HN EY  G+H +T+ +N F D++ +EF  +   ++   K  + K F ++    + P SV+W +KGYVTPVKNQ QCGSCWAFS TG++EGQ F+KT +L+S SEQ LVDCS   GNEGCNGG MD AFQY+    G++ E  YPY A + +C+Y+ +  +     + DI +  E+ L + +ATVGPISV IDA + SF  Y  GIY E  CSS  +DHGVL VGYG +  E    KYWLVKNSWG+ WG+ GY+KM+KD+ N CGIA+ ASYP +
Sbjct:    5 LILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN-RKPRKGKVF-QEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
[Close]
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537])

HSP 1 Score: 308.916 bits (790), Expect = 1.391e-102
Identity = 156/332 (46.99%), Postives = 215/332 (64.76%), Query Frame = 1 
Query:   97 LIVPCFAETIPWSGIFF-QGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            LI+  F   I  + + F    +  W+++K   N++Y    E  RR +WE+N++ I+ HN EY  G+H +T+ +N F D++ +EF  +   ++   K  + K F ++    + P SV+W +KGYVTPVKNQ QCGSCWAFS TG++EGQ F+KT +L+S SEQ LVDCS   GNEGCNGG MD AFQY+    G++ E  YPY A + +C+Y+ +  +     + DI +  E+ L + +ATVGPISV IDA + SF  Y  GIY E  CSS  +DHGVL VGYG +  E    KYWLVKNSWG+ WG+ GY+KM+KD+ N CGIA+ ASYP +
Sbjct:    5 LILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN-RKPRKGKVF-QEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
[Close]
BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSS (cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545])

HSP 1 Score: 291.967 bits (746), Expect = 5.982e-96
Identity = 148/312 (47.44%), Postives = 203/312 (65.06%), Query Frame = 1 
Query:  154 FDELWSEYKTKFNKVYDEENE-FVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCS-QSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
             D  W  +K  + K Y E+NE  VRR IWE+NL+F+  HN+E+++G H Y LG+N   D++ +E + +    R +    +R    K   +  LP+SV+W +KG VT VK Q  CG+CWAFS  G++E Q   KT KLVS S Q LVDCS + YGN+GCNGGFM  AFQYI+   GI+ ++ YPY AMD  CQY  +     C  YT++  G E+ L E +A  GP+SVG+DA +PSF  Y  G+Y E SC+   ++HGVL VGYG  + +G++YWLVKNSWG ++G  GYI+M+++K N CGIA+  SYP +
Sbjct:   24 LDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLR-VPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN-VNHGVLVVGYG--DLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331
[Close]
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 285.804 bits (730), Expect = 7.828e-94
Identity = 142/307 (46.25%), Postives = 193/307 (62.87%), Query Frame = 1 
Query:  160 ELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKS-VERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            E W +YK  F+K Y E  E    + + +N+  I+ HN ++ LGR  + +G+N   DL   ++  +    R    S ++  S      ++++P+ V+W     VT VKNQ  CGSCWAFS TG++EGQ+ +K  +LVS SEQ LVDCS  YGN GCNGG MDQAF+YI    G++ E  YPY   D  C ++K+ V    K Y D  +G EE L   +AT GPIS+ IDA + SFQ Y  G+Y +E CSS +LDHGVL VGYG D + G+ YW+VKNSWG  WG  GYI++++++NN CG+AT ASYP
Sbjct:   30 EKWDDYKEDFDKEYSESEEQTYMEAFVKNMIHIENHNRDHRLGRKTFEMGLNHIADLPFSQYRKLNGYRRLFGDSRIKNSSSFLAPFNVQVPDEVDWRDTHLVTDVKNQGMCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGD-YWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYP 335
[Close]
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 233.417 bits (594), Expect = 2.114e-75
Identity = 110/196 (56.12%), Postives = 138/196 (70.41%), Query Frame = 1 
Query:  490 CGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            CGSCWAFS TG++EGQ+ +K  +LVS SEQ LVDCS  YGN GCNGG MDQAF+YI    G++ E  YPY   D  C ++K+ V    K Y D  +G EE L   +AT GPIS+ IDA + SFQ Y  G+Y +E CSS +LDHGVL VGYG D + G+ YW+VKNSWG  WG  GYI++++++NN CG+AT ASYP
Sbjct:    2 CGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGD-YWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYP 196
[Close]
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 233.417 bits (594), Expect = 2.114e-75
Identity = 110/196 (56.12%), Postives = 138/196 (70.41%), Query Frame = 1 
Query:  490 CGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            CGSCWAFS TG++EGQ+ +K  +LVS SEQ LVDCS  YGN GCNGG MDQAF+YI    G++ E  YPY   D  C ++K+ V    K Y D  +G EE L   +AT GPIS+ IDA + SFQ Y  G+Y +E CSS +LDHGVL VGYG D + G+ YW+VKNSWG  WG  GYI++++++NN CG+AT ASYP
Sbjct:    2 CGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGD-YWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYP 196
[Close]
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597500:1 gene:WBGene00007055.1 transcript:F41E6.6.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 181.8 bits (460), Expect = 2.887e-52
Identity = 104/262 (39.69%), Postives = 152/262 (58.02%), Query Frame = 1 
Query:  307 GVNQFTDLSHQEFLDIYMKYR--PIVKSVERKSFDKKRKSLK---LPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEES--CSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMAS 1068
            G  +F+D++  EF  I + Y+    V  +E+ +F+K   ++    LP S +W +KG VT VKNQ  CGSCWAFSTTG++EG +F    KLVS SEQ+LVDC     ++GCNGG    A++ I++  G+E E  YPY      C   ++ +        ++    E ++ + L T GPIS+G++A+  + Q Y  G+       C    L+HGVL VGYG  +D  + YW+VKNSWG +WG  GY K+ + K N CG+  MA+
Sbjct:  219 GFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTINEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSM--DQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPH-DEVEMQKWLVTKGPISIGLNAN--TLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYG--KDGRKPYWIVKNSWGPNWGEAGYFKLYRGK-NVCGVQEMAT 472
[Close]
BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597469:1 gene:WBGene00007055.1 transcript:F41E6.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 181.8 bits (460), Expect = 2.887e-52
Identity = 104/262 (39.69%), Postives = 152/262 (58.02%), Query Frame = 1 
Query:  307 GVNQFTDLSHQEFLDIYMKYR--PIVKSVERKSFDKKRKSLK---LPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEES--CSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMAS 1068
            G  +F+D++  EF  I + Y+    V  +E+ +F+K   ++    LP S +W +KG VT VKNQ  CGSCWAFSTTG++EG +F    KLVS SEQ+LVDC     ++GCNGG    A++ I++  G+E E  YPY      C   ++ +        ++    E ++ + L T GPIS+G++A+  + Q Y  G+       C    L+HGVL VGYG  +D  + YW+VKNSWG +WG  GY K+ + K N CG+  MA+
Sbjct:  219 GFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTINEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSM--DQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPH-DEVEMQKWLVTKGPISIGLNAN--TLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYG--KDGRKPYWIVKNSWGPNWGEAGYFKLYRGK-NVCGVQEMAT 472
[Close]
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087593)

HSP 1 Score: 306.22 bits (783), Expect = 2.606e-101
Identity = 157/315 (49.84%), Postives = 205/315 (65.08%), Query Frame = 1 
Query:  160 ELWSEYKTKFNKVY-DEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDI--------YMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            E W  +K +  K Y DE  E  R +I+ EN   I KHN  +  G+  + L VN++ DL H EF  +        + + R   +S +  +F      + LP SV+W  KG VT VK+Q  CGSCWAFS+TG++EGQ+F+K+  LVS SEQ LVDCS  YGN GCNGG MD AF+YI    GI+ E  YPY A+D +C ++K  V    + +TDI QG E+ +AE +ATVGP+SV IDAS+ SFQ Y+ G+Y+E  C +  LDHGVL VG+G DE SGE YWLVKNSWG +WG  G+IKM ++K NQCGIA+ +SYP
Sbjct:   57 EEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISP-AHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYP 369
[Close]
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087592)

HSP 1 Score: 304.679 bits (779), Expect = 3.655e-101
Identity = 157/315 (49.84%), Postives = 205/315 (65.08%), Query Frame = 1 
Query:  160 ELWSEYKTKFNKVY-DEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDI--------YMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            E W  +K +  K Y DE  E  R +I+ EN   I KHN  +  G+  + L VN++ DL H EF  +        + + R   +S +  +F      + LP SV+W  KG VT VK+Q  CGSCWAFS+TG++EGQ+F+K+  LVS SEQ LVDCS  YGN GCNGG MD AF+YI    GI+ E  YPY A+D +C ++K  V    + +TDI QG E+ +AE +ATVGP+SV IDAS+ SFQ Y+ G+Y+E  C +  LDHGVL VG+G DE SGE YWLVKNSWG +WG  G+IKM ++K NQCGIA+ +SYP
Sbjct:   27 EEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISP-AHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYP 339
[Close]
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0339955)

HSP 1 Score: 302.368 bits (773), Expect = 2.750e-100
Identity = 158/333 (47.45%), Postives = 210/333 (63.06%), Query Frame = 1 
Query:  103 VPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDI--------YMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            + C  +   + GI  Q    L  E++  +    DE  E  R +I+ EN   I KHN  +  G+  + L VN++ DL H EF  +        + + R   +S +  +F      + LP SV+W  KG VT VK+Q  CGSCWAFS+TG++EGQ+F+K+  LVS SEQ LVDCS  YGN GCNGG MD AF+YI    GI+ E  YPY A+D +C ++K  V    + +TDI QG E+ +AE +ATVGP+SV IDAS+ SFQ Y+ G+Y+E  C +  LDHGVL VG+G DE SGE YWLVKNSWG +WG  G+IKM ++K NQCGIA+ +SYP
Sbjct:   10 LDCSVQCAKYPGIL-QNLLRLVLEHRKNYQ---DETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISP-AHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYP 336
[Close]
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0304021)

HSP 1 Score: 270.396 bits (690), Expect = 4.868e-89
Identity = 129/219 (58.90%), Postives = 162/219 (73.97%), Query Frame = 1 
Query:  421 LKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            + LP SV+W  KG VT VK+Q  CGSCWAFS+TG++EGQ+F+K+  LVS SEQ LVDCS  YGN GCNGG MD AF+YI    GI+ E  YPY A+D +C ++K  V    + +TDI QG E+ +AE +ATVGP+SV IDAS+ SFQ Y+ G+Y+E  C +  LDHGVL VG+G DE SGE YWLVKNSWG +WG  G+IKM ++K NQCGIA+ +SYP
Sbjct:   30 VTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDE-SGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYP 247
[Close]
BLAST of Cathepsin L2 vs. Ensembl Fly
Match: CG6347 (gene:FBgn0033874 transcript:FBtr0087637)

HSP 1 Score: 214.927 bits (546), Expect = 4.560e-66
Identity = 115/325 (35.38%), Postives = 182/325 (56.00%), Query Frame = 1 
Query:  148 QGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKS-----FDKKR--KSLKLPNSVNWVKKGYVTPVKNQ-LQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSK------RKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            Q FD+    +  +  KVY +E    R  I+   +  I   N   + G   + LGVN   D++ +E   +      I +  ER +     F   R   S  LP   +W +KG VTP   Q + CG+CW+F+TTG++EG  F++T  L S S+Q LVDC+  YGN GC+GGF +  F+YI   G+   + YPYT  +  C+ ++      R+ + + ++Y  I  G EE + E +AT+GP++  ++A   SF+ Y+GGIY++E C+  +L+H V  VGYG   ++G  YW++KNS+  +WG  G++++ ++    CGIA+  SYP L
Sbjct:   36 QNFDD----FLRQTGKVYSDEERVYRESIFAAKMSLITLSNKNADNGVSGFRLGVNTLADMTRKEIATLLGS--KISEFGERYTNGHINFVTARNPASANLPEMFDWREKGGVTPPGFQGVGCGACWSFATTGALEGHLFRRTGVLASLSQQNLVDCADDYGNMGCDGGFQEYGFEYIRDHGVTLANKYPYTQTEMQCRQNETAGRPPRESLVKIRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGGIYEDEECNQGELNHSVTVVGYGT--ENGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIASECSYPIL 352
[Close]
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: si:dkey-269i1.4 (si:dkey-269i1.4 [Source:ZFIN;Acc:ZDB-GENE-121214-37])

HSP 1 Score: 332.028 bits (850), Expect = 7.807e-112
Identity = 162/335 (48.36%), Postives = 219/335 (65.37%), Query Frame = 1 
Query:   82 IRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDG-NCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            +   LL+  C +     S I  Q  D+ W+ +K++  K Y E+ E  RR IWEENL+ I++HN EY+ G H + +G+NQF D++++EF      Y+       +     +      P  V+W ++GYVTPVK+Q QCGSCW+FS+TG++EGQ F+KT KL+S SEQ LVDCS+ +GN+GCNGG MDQAFQY+ +  G++ E  YPY A D   C+Y  R  + +   + DI +G+E  L   +A VGP+SV IDAS+ S Q Y  GIY E +CSS++LDH VL VGYG    + +G +YW+VKNSW D WG  GYI M+KDKNN CGIATMASYP
Sbjct:    1 MMFALLVTLCISAVFAASSIDIQ-LDDHWNSWKSQHGKSYHEDVEVGRRMIWEENLRKIEQHNFEYSYGNHTFKMGMNQFGDMTNEEFRHAMNGYKHDPNQTSQGPLFMEPSFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPHGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPKGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGIATMASYP 334
[Close]
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: si:dkey-239j18.2 (si:dkey-239j18.2 [Source:ZFIN;Acc:ZDB-GENE-121214-52])

HSP 1 Score: 328.176 bits (840), Expect = 2.883e-110
Identity = 166/339 (48.97%), Postives = 221/339 (65.19%), Query Frame = 1 
Query:   70 MMHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDG-NCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            MM  + + L I   FA       I  Q  D+ W+ +K++  K Y E+ E  RR IWEENL+ I++HN EY+LG H + +G+NQF D++++EF      Y+       +     + K    P  V+W ++GYVTPVK+Q QCGSCW+FS+TG++EGQ F+KT KL+S SEQ LVDCS+ +GN+GCNGG MDQAFQY+ +  G++ E  YPY A D   C+Y  R  + +   + DI +G+E  L   +A VGP+SV IDAS+ S Q Y  GIY E +C+S QLDH VL VGYG    + +G +YW+VKNSW D WG  GYI M+KDKNN CGIATMASYP
Sbjct:    1 MMFALLVTLYISAVFAAP----SIDIQ-LDDHWNSWKSQHGKSYHEDVEVGRRMIWEENLRKIEQHNFEYSLGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTSQGPLFMEPKFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPHGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPKGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACTS-QLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGIATMASYP 333
[Close]
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: si:dkey-239j18.2 (si:dkey-239j18.2 [Source:ZFIN;Acc:ZDB-GENE-121214-52])

HSP 1 Score: 328.176 bits (840), Expect = 2.883e-110
Identity = 166/339 (48.97%), Postives = 221/339 (65.19%), Query Frame = 1 
Query:   70 MMHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDG-NCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            MM  + + L I   FA       I  Q  D+ W+ +K++  K Y E+ E  RR IWEENL+ I++HN EY+LG H + +G+NQF D++++EF      Y+       +     + K    P  V+W ++GYVTPVK+Q QCGSCW+FS+TG++EGQ F+KT KL+S SEQ LVDCS+ +GN+GCNGG MDQAFQY+ +  G++ E  YPY A D   C+Y  R  + +   + DI +G+E  L   +A VGP+SV IDAS+ S Q Y  GIY E +C+S QLDH VL VGYG    + +G +YW+VKNSW D WG  GYI M+KDKNN CGIATMASYP
Sbjct:    1 MMFALLVTLYISAVFAAP----SIDIQ-LDDHWNSWKSQHGKSYHEDVEVGRRMIWEENLRKIEQHNFEYSLGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTSQGPLFMEPKFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPHGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPKGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACTS-QLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGIATMASYP 333
[Close]
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: si:dkey-269i1.4 (si:dkey-269i1.4 [Source:ZFIN;Acc:ZDB-GENE-121214-37])

HSP 1 Score: 327.405 bits (838), Expect = 4.913e-110
Identity = 160/335 (47.76%), Postives = 217/335 (64.78%), Query Frame = 1 
Query:   82 IRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDG-NCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            +   LL+  C +     S I  Q  D+ W+ +K++  K Y E+ E  RR IWEENL+ I++HN EY+ G H + +G+NQF D++++EF      Y+       +     +      P  V+W ++GYVTPVK+Q QCGSCW+FS+TG++EGQ F+KT KL+S SEQ LVDCS+  GN+GCNGG MDQAFQY+ +  G++ E  YPY A D   C+Y  R  + +   + DI +G+E  L   +A VGP+SV IDAS+ S Q Y  GIY E +CSS++LDH VL VGYG    + +G +YW+VKNSW D WG  GYI M+KDKNN CG+AT ASYP
Sbjct:    1 MMFALLVTLCISAVFAASSIDIQ-LDDHWNSWKSQHGKSYHEDVEVGRRMIWEENLKKIEQHNFEYSYGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTSQGPLFMEPSFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPRGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGVATTASYP 334
[Close]
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: ctslb (cathepsin Lb [Source:ZFIN;Acc:ZDB-GENE-980526-285])

HSP 1 Score: 327.02 bits (837), Expect = 7.110e-110
Identity = 160/335 (47.76%), Postives = 217/335 (64.78%), Query Frame = 1 
Query:   82 IRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDG-NCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            +   LL+  C +     S I  Q  D+ W+ +K++  K Y E+ E  RR IWEENL+ I++HN EY+ G H + +G+NQF D++++EF      Y+       +     +      P  V+W ++GYVTPVK+Q QCGSCW+FS+TG++EGQ F+KT KL+S SEQ LVDCS+  GN+GCNGG MDQAFQY+ +  G++ E  YPY A D   C+Y  R  + +   + DI +G+E  L   +A VGP+SV IDAS+ S Q Y  GIY E +CSS++LDH VL VGYG    + +G +YW+VKNSW D WG  GYI M+KDKNN CG+AT ASYP
Sbjct:    1 MMFALLVTLCISAVFAASSIDIQ-LDDHWNSWKSQHGKSYHEDVEVGRRMIWEENLRKIEQHNFEYSYGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTSQGPLFMEPSFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQGNQGCNGGIMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGFVDIPRGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGVATSASYP 334
[Close]
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 317.005 bits (811), Expect = 8.639e-106
Identity = 160/313 (51.12%), Postives = 212/313 (67.73%), Query Frame = 1 
Query:  151 GFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGN-CQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGV---DEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
              D  W+ +K    K Y  + E  RR +WE+NL+ I+ HN+E++LG+H ++LG+NQF D++++EF  +   Y+   K   R S      + + P SV+W KKGYVTPVK+Q QCGSCWAFSTTG++EGQ+++ T K++S SEQ LVDCS++ GN+GCNGG MDQAFQY+    GI+ E  YPYTA D   C Y           + D+  GSE+DL   +A+VGP+SV +DA + SFQ Y  GIY E  CSS  LDHGVL VGYG    DED G+KYW+VKNSW + WG +GYI ++KD++N CGIAT ASYP
Sbjct:   24 ALDNHWNLWKNWHKKSYAPKEEGWRRVLWEKNLRMIEFHNLEHSLGKHSHSLGMNQFGDMTNEEFRQLMNGYKNQKKI--RGSTFLAPNNFESPKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPYTAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDED-GKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYP 333
[Close]
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 317.005 bits (811), Expect = 1.365e-105
Identity = 163/338 (48.22%), Postives = 220/338 (65.09%), Query Frame = 1 
Query:   76 HFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGN-CQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGV---DEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            + + + L I      T+  +       D  W+ +K    K Y  + E  RR +WE+NL+ I+ HN+E++LG+H ++LG+NQF D++++EF  +   Y+   K   R S      + + P SV+W KKGYVTPVK+Q QCGSCWAFSTTG++EGQ+++ T K++S SEQ LVDCS++ GN+GCNGG MDQAFQY+    GI+ E  YPYTA D   C Y           + D+  GSE+DL   +A+VGP+SV +DA + SFQ Y  GIY E  CSS  LDHGVL VGYG    DED G+KYW+VKNSW + WG +GYI ++KD++N CGIAT ASYP
Sbjct:    6 YIMALYLGIAAICLTTVFAAPTTDPALDNHWNLWKNWHKKSYAPKEEGWRRVLWEKNLRMIEFHNLEHSLGKHSHSLGMNQFGDMTNEEFRQLMNGYKNQKKI--RGSTFLAPNNFESPKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPYTAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDED-GKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYP 340
[Close]
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: ano1 (anoctamin 1, calcium activated chloride channel [Source:Xenbase;Acc:XB-GENE-5967576])

HSP 1 Score: 286.574 bits (732), Expect = 7.750e-94
Identity = 140/315 (44.44%), Postives = 201/315 (63.81%), Query Frame = 1 
Query:  151 GFDELWSEYKTKFNKVYDEENEFVRRQI-WEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSL---KLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
              D  W  +K   NK Y++E E ++R+I WE+NL  +  HN+EY++G H Y LG+N   D++ +E            +S  + +F  ++ S    K+P+S++W  KG V+ VKNQ  CGSCWAFS  G++EGQ   KT KLVS S Q LVDCS  YGN+GC GGFM QAFQY++   GI+ +S YPY AMD  C Y      + C  YT+I  G+E++L + L ++GPISV ID + PSF  Y  G+Y + +CS  +++HGVLAVGYG    +G+ +WL+KNSWG  +G  GY++++++K N CG+A+   YP +
Sbjct:   22 ALDNHWLLWKNTHNKDYEDEIEDLQRRITWEKNLNLVNMHNLEYSMGMHTYELGMNHLADMTSEEIKSKLTGLILPPQSERQATFSSQKNSTFGGKVPDSIDWRDKGCVSDVKNQGGCGSCWAFSAVGALEGQLMLKTGKLVSLSPQNLVDCSSKYGNKGCGGGFMTQAFQYVIDNKGIDSDSYYPYHAMDEKCHYDPTGKASTCAKYTEIVPGTEDNLKQALGSIGPISVAIDGTRPSFFLYRSGVYSDPTCSH-EVNHGVLAVGYG--NLNGQDFWLLKNSWGTKYGDQGYVRIARNKGNLCGVASYTCYPEI 333
[Close]
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: harbi1 (harbinger transposase derived 1 [Source:Xenbase;Acc:XB-GENE-6077433])

HSP 1 Score: 283.493 bits (724), Expect = 1.242e-92
Identity = 143/317 (45.11%), Postives = 203/317 (64.04%), Query Frame = 1 
Query:  139 IFFQG-FDELWSEYKTKFNKVYDEE-NEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIY--MKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            +++ G  D  W  +KT ++K YD + +E +RR IWE+NL  I+ HN+E+  G H Y LG+N+F D++ +E + +   +K    +      S D+   S ++PNS+++ KKGYVTP+++Q +CGSCWAFST G++EGQ  KKT KLV  S Q LVDC +   N GC GG+M  AF+Y+ K  GI+ E  YPY  MD  C+Y+        K + ++ +GSE  L + +  VGPISVGIDA   +F  Y  GIY ++SC    ++H VLAVGYG  +    KYW++KNSWG+ WG  GYI M+++K N CGIA +ASYP
Sbjct:   18 LYYNGTLDSEWEIWKTTYHKHYDNKIHELMRRLIWEKNLNIIRSHNLEFTQGLHTYELGMNKFGDMTSEEVVRMMTGLKVHTGMGPTNLTS-DEDEASQRIPNSIDYRKKGYVTPIRDQGECGSCWAFSTVGALEGQLMKKTGKLVGISPQNLVDCVKD--NFGCGGGYMTTAFKYVKKNKGIDSEEAYPYVGMDQKCKYNVSGRAAEIKGFKEVKKGSETALKKAVGLVGPISVGIDAGLDTFFLYKKGIYYDKSCDGDSINHAVLAVGYGKQKKG--KYWIIKNSWGEDWGNKGYILMAREKGNACGIANLASYP 329
[Close]
BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: ctsk (cathepsin K (pycnodysostosis) [Source:NCBI gene;Acc:448216])

HSP 1 Score: 271.166 bits (692), Expect = 8.122e-88
Identity = 136/309 (44.01%), Postives = 190/309 (61.49%), Query Frame = 1 
Query:  154 FDELWSEYKTKFNKVYDEE-NEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
             D  W  +K  +++ Y+ + +E  RRQIWE+NL  I +HN E++ G H Y L +N   D++ +E +   M  +         ++  +  S ++P  +++ KKGYVTPV NQ  CGSCWAFS+ G++EGQ  KKT KLVS S Q LVDC     N GC GG+M  AF Y+    GI+ ++ YPY   D  C Y+       CK Y +I  GSE+ L   +A VGP+SV IDAS PSFQ Y  G+Y + SC+   ++H VL VGYG   + G K+W++KNSWGD WG  GY+ +++DK N CGIA++AS+P
Sbjct:   31 LDSKWELWKKTYHRQYNGQLDEIRRRQIWEKNLNLISQHNKEFSQGLHTYDLAMNHLGDMTSEEVVQKMMGLKVPPNHRPNNTYIPEWNS-RIPEYIDYRKKGYVTPVHNQGICGSCWAFSSVGALEGQLMKKTGKLVSLSPQNLVDCDTD--NYGCEGGYMTNAFGYVRDNGGIDSDAEYPYVGQDEGCHYNPADKAATCKGYKEIPVGSEKALKRAVANVGPVSVSIDASLPSFQFYKKGVYYDSSCNPDAVNHAVLVVGYG--NEKGIKHWIIKNSWGDWWGKKGYVLLARDKKNACGIASLASFP 334
[Close]
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564])

HSP 1 Score: 317.39 bits (812), Expect = 4.282e-106
Identity = 158/314 (50.32%), Postives = 213/314 (67.83%), Query Frame = 1 
Query:  142 FFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            F Q F   W ++K+   ++Y    E  RR IWE+N++ IQ HN EY+ G+H +++ +N F D++++EF  +   YR   +  ++    ++   LK+P SV+W +KG VTPVKNQ QCGSCWAFS +G +EGQ F KT KL+S SEQ LVDCS + GN+GCNGG MD AFQYI +  G++ E  YPY A DG+C+Y     +     + DI Q  E+ L + +ATVGPISV +DAS+PS Q Y+ GIY E +CSS  LDHGVL VGYG +  + +  KYWLVKNSWG  WG+ GYIK++KD++N CG+AT ASYP
Sbjct:   21 FDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRH--QKHKKGRLFQEPLMLKIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYP 331
[Close]
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564])

HSP 1 Score: 317.39 bits (812), Expect = 4.282e-106
Identity = 158/314 (50.32%), Postives = 213/314 (67.83%), Query Frame = 1 
Query:  142 FFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            F Q F   W ++K+   ++Y    E  RR IWE+N++ IQ HN EY+ G+H +++ +N F D++++EF  +   YR   +  ++    ++   LK+P SV+W +KG VTPVKNQ QCGSCWAFS +G +EGQ F KT KL+S SEQ LVDCS + GN+GCNGG MD AFQYI +  G++ E  YPY A DG+C+Y     +     + DI Q  E+ L + +ATVGPISV +DAS+PS Q Y+ GIY E +CSS  LDHGVL VGYG +  + +  KYWLVKNSWG  WG+ GYIK++KD++N CG+AT ASYP
Sbjct:   21 FDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRH--QKHKKGRLFQEPLMLKIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYP 331
[Close]
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsll3 (cathepsin L-like 3 [Source:MGI Symbol;Acc:MGI:1917452])

HSP 1 Score: 306.605 bits (784), Expect = 7.758e-102
Identity = 158/330 (47.88%), Postives = 207/330 (62.73%), Query Frame = 1 
Query:   88 IILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESV-YPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            + LL   C    +  +       D +W E+KTK  K Y+  +E  +R +WE N + I  HN +Y  G+H ++L +N F DL++ EF ++   ++     +  K F +      +P SV+W   GYVTPVK+Q  CGSCWAFS  GS+EGQ F+KT KLV  S Q LVDCS S GN+GC+GG  D AFQY+   G    SV YPY A++G C+Y+ +        + ++ Q SE+ L + +ATVGPISVGID  + SFQ Y  G+Y E  CSST LDH VL VGYG +E  G KYWLVKNSWG  WG+NGYIKM+KD+NN CGIA+ ASYP
Sbjct:    4 VFLLATLCLG-VVSAAPAHNPSLDAVWEEWKTKHKKTYNMNDEGQKRAVWENNKKMIDLHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQGQKTKMMMKVFQEPLLG-DVPKSVDWRDHGYVTPVKDQGSCGSCWAFSAVGSLEGQMFRKTGKLVPLSVQNLVDCSWSQGNQGCDGGLPDLAFQYVKDNGGLDTSVSYPYEALNGTCRYNPKNSAATVTGFVNV-QSSEDALMKAVATVGPISVGIDTKHKSFQFYKEGMYYEPDCSSTVLDHAVLVVGYG-EESDGRKYWLVKNSWGRDWGMNGYIKMAKDRNNNCGIASDASYP 329
[Close]
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: BC051665 (cDNA sequence BC051665 [Source:MGI Symbol;Acc:MGI:2682300])

HSP 1 Score: 300.827 bits (769), Expect = 1.154e-99
Identity = 154/334 (46.11%), Postives = 206/334 (61.68%), Query Frame = 1 
Query:   88 IILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSL--KLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            + LL   C    +  +       D +W E+KTK  K Y+   E  +R +WE N++ I  HN +Y  G+H + L +N F DL++ EF ++   +    +S+  K     ++ L   +P SV+W   GYVTPVK+Q  CGSCWAFS  GS+EGQ F+KT KLV  SEQ L+DCS SYGN GCNGG M+ AFQY+ +  G++    Y Y A DG C+Y  +        +  +   SE+ L   +A+VGP+SVGID  + SF+ Y GG Y E  CSST LDH VL VGYG +E  G KYWLVKNSWG+ WG++GYIKM+KD++N CGIAT A YP +
Sbjct:    4 VFLLATLCLG-VVSAAPAHDPSLDAVWEEWKTKHRKTYNMNEEAQKRAVWENNMKMIGLHNEDYLKGKHGFNLEMNAFGDLTNTEFRELMTGF----QSMGHKEMTIFQEPLLGDVPKSVDWRDHGYVTPVKDQGHCGSCWAFSAVGSLEGQIFRKTGKLVPLSEQNLMDCSWSYGNVGCNGGLMELAFQYVKENRGLDTRESYAYEAWDGPCRYDPKYSAVNITGFVKVPL-SEDALMNAVASVGPVSVGIDTHHHSFRFYRGGTYYEPDCSSTNLDHAVLVVGYG-EESDGRKYWLVKNSWGEDWGMDGYIKMAKDRDNNCGIATYAIYPTV 330
[Close]
BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: 4930486L24Rik (RIKEN cDNA 4930486L24 gene [Source:MGI Symbol;Acc:MGI:1922258])

HSP 1 Score: 290.812 bits (743), Expect = 1.352e-95
Identity = 150/335 (44.78%), Postives = 202/335 (60.30%), Query Frame = 1 
Query:   79 FIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGV--DEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            F+ I+ L +   A T+  S       D  W+E++TK  K Y+   E +RR +WE+N + I+ HN EY  G+H +T+ +N F DL++ EF+ +   +R   + ++R    +  + L +P  V+W   GYVTPVKNQ  C S WAFS TGS+EGQ FKKT +LV  SEQ L+DC  S     C+GGFM  AFQY+    G+  E  YPY      C+Y         +++  I  G EE L + +A VGPISV +DAS+ SFQ Y+ GIY E  C    L+H VL VGYG   +E  G  YWLVKNSWG+ WG+ GYIK++KD NN CGIAT+A+YP
Sbjct:    6 FLAILCLEIDSTAPTLDPS------LDVQWNEWRTKHGKAYNVNEERLRRAVWEKNFKMIELHNWEYLEGKHDFTMTMNAFGDLTNTEFVKMMTGFRR--QKIKRMHVFQDHQFLYVPKYVDWRMLGYVTPVKNQGYCASSWAFSATGSLEGQMFKKTGRLVPLSEQNLLDCMGSNVTHDCSGGFMQNAFQYVKDNGGLATEESYPYIGPGRKCRYHAENSAANVRDFVQI-PGREEALMKAVAKVGPISVAVDASHDSFQFYDSGIYYEPQCKRVHLNHAVLVVGYGFEGEESDGNSYWLVKNSWGEEWGMKGYIKIAKDWNNHCGIATLATYP 331
[Close]
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|O60911|CATL2_HUMAN (Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2)

HSP 1 Score: 328.176 bits (840), Expect = 1.694e-109
Identity = 163/339 (48.08%), Postives = 218/339 (64.31%), Query Frame = 1 
Query:   73 MHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            M+   ++       A  +P    F Q  D  W ++K    ++Y    E  RR +WE+N++ I+ HN EY+ G+H +T+ +N F D++++EF  +   +R   +   +    ++   L LP SV+W KKGYVTPVKNQ QCGSCWAFS TG++EGQ F+KT KLVS SEQ LVDCS+  GN+GCNGGFM +AFQY+ +  G++ E  YPY A+D  C+Y     +     +T +  G E+ L + +ATVGPISV +DA + SFQ Y  GIY E  CSS  LDHGVL VGYG +    +  KYWLVKNSWG  WG NGY+K++KDKNN CGIAT ASYPN+
Sbjct:    1 MNLSLVLAAFCLGIASAVP---KFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRN--QKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
[Close]
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P07154|CATL1_RAT (Cathepsin L1 OS=Rattus norvegicus OX=10116 GN=Ctsl PE=1 SV=2)

HSP 1 Score: 320.857 bits (821), Expect = 1.739e-106
Identity = 158/314 (50.32%), Postives = 215/314 (68.47%), Query Frame = 1 
Query:  142 FFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            F Q F+  W ++K+   ++Y    E  RR +WE+N++ IQ HN EY+ G+H +T+ +N F D++++EF  I   YR   +  ++    ++   L++P +V+W +KG VTPVKNQ QCGSCWAFS +G +EGQ F KT KL+S SEQ LVDCS   GN+GCNGG MD AFQYI +  G++ E  YPY A DG+C+Y     +     + DI Q  E+ L + +ATVGPISV +DAS+PS Q Y+ GIY E +CSS  LDHGVL VGYG +  + + +KYWLVKNSWG  WG++GYIK++KD+NN CG+AT ASYP
Sbjct:   21 FDQTFNAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQLHNGEYSNGKHGFTMEMNAFGDMTNEEFRQIVNGYRH--QKHKKGRLFQEPLMLQIPKTVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVKNSWGKEWGMDGYIKIAKDRNNHCGLATAASYP 331
[Close]
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P06797|CATL1_MOUSE (Cathepsin L1 OS=Mus musculus OX=10090 GN=Ctsl PE=1 SV=2)

HSP 1 Score: 317.39 bits (812), Expect = 2.995e-105
Identity = 158/314 (50.32%), Postives = 213/314 (67.83%), Query Frame = 1 
Query:  142 FFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            F Q F   W ++K+   ++Y    E  RR IWE+N++ IQ HN EY+ G+H +++ +N F D++++EF  +   YR   +  ++    ++   LK+P SV+W +KG VTPVKNQ QCGSCWAFS +G +EGQ F KT KL+S SEQ LVDCS + GN+GCNGG MD AFQYI +  G++ E  YPY A DG+C+Y     +     + DI Q  E+ L + +ATVGPISV +DAS+PS Q Y+ GIY E +CSS  LDHGVL VGYG +  + +  KYWLVKNSWG  WG+ GYIK++KD++N CG+AT ASYP
Sbjct:   21 FDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRH--QKHKKGRLFQEPLMLKIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYP 331
[Close]
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|Q9GKL8|CATL1_CHLAE (Cathepsin L1 OS=Chlorocebus aethiops OX=9534 GN=CTSL PE=1 SV=1)

HSP 1 Score: 309.686 bits (792), Expect = 3.228e-102
Identity = 155/316 (49.05%), Postives = 208/316 (65.82%), Query Frame = 1 
Query:  142 FFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            F    +  W+++K   N++Y    E  RR +WE+N++ I+ HN EY+ G+H +T+ +N F D++ +EF  +   ++   K  + K F ++    + P SV+W +KGYVTPVKNQ QCGSCWAFS TG++EGQ F+KT KLVS SEQ LVDCS   GNEGCNGG MD AFQY+    G++ E  YPY A + +C+Y+    +     + DI +  E+ L + +ATVGPISV IDA + SF  Y  GIY E  CSS  +DHGVL VGYG +  E    KYWLVKNSWG+ WG+ GYIKM+KD+ N CGIA+ ASYP +
Sbjct:   21 FNHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHSFTMAMNTFGDMTSEEFRQVMNGFQN-RKPRKGKVF-QEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVADNGGLDSEESYPYEATEESCKYNPEYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFMFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNSKYWLVKNSWGEEWGMGGYIKMAKDRRNHCGIASAASYPTV 333
[Close]
BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P07711|CATL1_HUMAN (Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 SV=2)

HSP 1 Score: 308.916 bits (790), Expect = 6.680e-102
Identity = 156/332 (46.99%), Postives = 215/332 (64.76%), Query Frame = 1 
Query:   97 LIVPCFAETIPWSGIFF-QGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            LI+  F   I  + + F    +  W+++K   N++Y    E  RR +WE+N++ I+ HN EY  G+H +T+ +N F D++ +EF  +   ++   K  + K F ++    + P SV+W +KGYVTPVKNQ QCGSCWAFS TG++EGQ F+KT +L+S SEQ LVDCS   GNEGCNGG MD AFQY+    G++ E  YPY A + +C+Y+ +  +     + DI +  E+ L + +ATVGPISV IDA + SF  Y  GIY E  CSS  +DHGVL VGYG +  E    KYWLVKNSWG+ WG+ GY+KM+KD+ N CGIA+ ASYP +
Sbjct:    5 LILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN-RKPRKGKVF-QEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
[Close]
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A2U8U447 (Cathepsin L2 OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 394.815 bits (1013), Expect = 3.796e-133
Identity = 191/333 (57.36%), Postives = 234/333 (70.27%), Query Frame = 1 
Query:   82 IRIILL--IVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            ++IILL  I     + +P         ++ W  YK KF+K Y+  NE  RR IWE NL+FIQ+HN+EY+LG+H Y LG+N+F D++H+EF   Y+  +PI ++     F        LP  ++W  KGYVTPVKNQ QCGSCWAFSTTGS+EGQ+F+K+ KLVSFSEQQLVDCS+S+ N GCNGG MD AF YI KFGIE E  YPY A DG C Y K K++  C  + DI  G+E DL   +AT GPISV IDASN SFQ Y GGIY+E  CSS  LDHGVLA+GYG   ++ E YW+VKNSW  SWG++GYI+MSKDK NQCGIATMASYP
Sbjct:    1 MKIILLTSIFLVTIQAVPHKFTINSELNDEWEVYKMKFSKKYETLNEISRRIIWENNLKFIQQHNVEYDLGKHTYYLGLNEFADMTHEEFKAKYLGLKPINRNFTSSRFIIPENIGDLPTRIDWRTKGYVTPVKNQGQCGSCWAFSTTGSLEGQHFRKSGKLVSFSEQQLVDCSRSFDNLGCNGGLMDNAFSYIQKFGIENEISYPYVANDGVCAYDKTKIVGTCTGFVDIKTGNETDLMAAVATQGPISVAIDASNDSFQFYRGGIYNEPHCSSKDLDHGVLAIGYG--SENNENYWIVKNSWDISWGMSGYIRMSKDKMNQCGIATMASYP 331
[Close]
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A0B5ITX6 (Cathepsin L3 OS=Nephilengys cruentata OX=450950 PE=2 SV=1)

HSP 1 Score: 364.385 bits (934), Expect = 3.041e-121
Identity = 179/337 (53.12%), Postives = 231/337 (68.55%), Query Frame = 1 
Query:   70 MMHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKS-LKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            M     I  L V   A  +P    F   +D+ W  +KTKFNK Y++  EF RR +WE NL+ + KHNIEY LG  +Y  G+N+++D++HQEF+      +  V S  +  +   R S + LP++V+W K G VTP+KNQ QCGSCWAFSTTGS+EGQ+ KKT KLVS SEQ LVDCSQ  GN+GC GG MDQ F+YI +  GI+ E+ YPY A+D  C++ ++ V   C  Y D+  G E+ L + +AT+GPISV IDAS  SFQ Y GG+Y EE+CS+ +LDHGVL VGYG  ++ GE YWLVKNSWG SWG+ GYI M+++KNNQCGIAT ASYP
Sbjct:    1 MKAIALICCLFVVIAARKLP----FNPDYDQHWEVFKTKFNKNYEKNEEFARRLVWEVNLEAVIKHNIEYELGMQRYRKGINEYSDMTHQEFVRRMNGLKKGVNSTTKSVYTFDRLSNVVLPDTVDWRKDGMVTPIKNQQQCGSCWAFSTTGSLEGQHKKKTGKLVSLSEQNLVDCSQKQGNDGCEGGLMDQGFEYIKENNGIDTEASYPYEAIDDKCRFKRQSVGATCTGYVDVKSGDEDALKQAVATIGPISVAIDASQFSFQLYRGGVYYEENCSTEELDHGVLVVGYGTTQN-GEDYWLVKNSWGTSWGIKGYIMMARNKNNQCGIATQASYP 332
[Close]
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A0L8HPF9 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22009826mg PE=3 SV=1)

HSP 1 Score: 363.229 bits (931), Expect = 9.040e-121
Identity = 181/338 (53.55%), Postives = 228/338 (67.46%), Query Frame = 1 
Query:   73 MHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYD-EENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLK-LPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            M  +  +LL V C A ++P S  F    D+ W  Y   FNK Y+  ENEFVRR IWE+NLQ++ +HN+E ++G H Y LG+N++ DL ++EF+       P   +  +        ++K LP++V+W  KGYVT VKNQ QCGSCWAFSTTGS+EGQ FKKT KLVS SEQ LVDCS S+GN GC GG MD AF+YI KFGI+ E+ YPY   D  C+Y K  V+     Y D+   SE+ L   +A VGPISV IDA + SFQ Y  G+Y E  CS+T LDHGVLAVGYG   D+G+ YWLVKNSWG SWG+ GYIKM++++NN CGIAT ASYP +
Sbjct:    3 MKSLVAVLLFVAC-AASVPLSDNFL---DQSWQTYMKLFNKKYNTAENEFVRRVIWEKNLQYVNQHNLEADMGLHTYWLGLNEYADLENREFVQRMNNLIPRNLTTYKPKLIFANDNIKDLPDTVDWRTKGYVTEVKNQAQCGSCWAFSTTGSLEGQIFKKTGKLVSLSEQNLVDCSGSFGNNGCEGGLMDNAFKYIKKFGIDSEASYPYEGRDAKCRYKKSDVVATDTGYVDVKSMSEDSLQSAVAKVGPISVAIDAGHLSFQLYKHGVYKESRCSATALDHGVLAVGYGT--DNGQDYWLVKNSWGGSWGVKGYIKMARNQNNMCGIATQASYPTV 334
[Close]
BLAST of Cathepsin L2 vs. TrEMBL
Match: W4YG81 (Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1)

HSP 1 Score: 357.451 bits (916), Expect = 1.706e-118
Identity = 176/332 (53.01%), Postives = 227/332 (68.37%), Query Frame = 1 
Query:   91 ILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVY-DEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYR--PIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            +LL+  C   ++  S   F  FDE W+++K +  K Y  +E E  R+ IWE+NL  + KHN++Y+LG   Y LG+NQF DL ++EF+ +   +R     K+ +  +F       +LP +V+W  KGYVTPVK+Q QCGSCWAFSTTGS+EGQ+FK T KLVS SEQ LVDCS   GNEGC+GG MDQAFQYI+K  GI+ E  YPY A+DG C + K  +      YTD+   SE  L + +A +GPISV IDAS+ SFQ Y  G+Y+E  CSST LDHGVLAVGYG   D G  YW+VKNSW ++WG+NGY+ MS++K+NQCGIAT ASYP
Sbjct:    6 VLLVAACVVSSLSMS---FTDFDEDWNQWKNEHGKRYLSDEEEASRKLIWEKNLDIVIKHNLKYDLGHFTYALGMNQFADLKNEEFVAMMTGFRVNGTSKAAKGSTFLPSNNIGELPKTVDWRTKGYVTPVKDQGQCGSCWAFSTTGSLEGQHFKATGKLVSLSEQNLVDCSGKEGNEGCDGGLMDQAFQYIIKAGGIDTEESYPYKAVDGECHFKKANIGATVTGYTDVTSDSETALQKAVAHIGPISVAIDASHMSFQLYKSGVYNEPDCSSTLLDHGVLAVGYGTTSD-GTDYWIVKNSWAETWGMNGYLWMSRNKDNQCGIATQASYP 333
[Close]
BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A4Y2RKW0 (Cathepsin L OS=Araneus ventricosus OX=182803 GN=CATL_10 PE=3 SV=1)

HSP 1 Score: 355.14 bits (910), Expect = 1.618e-117
Identity = 177/335 (52.84%), Postives = 220/335 (65.67%), Query Frame = 1 
Query:   73 MHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYI-MKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            M F+ +  L V   +  I          +E W  +K  F KVYDE  E  RR IWE+ +  + +HN+ Y+LG H Y  G+N+++D+ H+EF+ I+  +R         S      + ++P+ V+W  KG VTPVKNQ QCGSCWAFSTTGS+EGQ+ KKT +LVS SEQ LVDCS   GNEGC GG MDQAF+Y+ +  GI+ E  YPYTA DG C + K  V      Y DI  G EE L + +AT+GPISV IDAS+ SFQ+Y  GIYDE  CSS  LDHGVLAVGYG ++  G  YWLVKNSWG SWG+ GYIKMS++KNNQCGIAT ASYP
Sbjct:    1 MKFLALFALFVVAASRHIQLD----PKLNEHWENFKKVFGKVYDETEEVSRRMIWEQRVSDVVRHNLRYDLGLHSYRKGINEYSDMEHEEFVRIFNGFRRQPGQKTNASTWVPVFNAQIPDQVDWRTKGLVTPVKNQQQCGSCWAFSTTGSLEGQHKKKTGQLVSLSEQNLVDCSGPEGNEGCGGGLMDQAFEYVKVNKGIDTEKSYPYTAEDGTCHFKKSSVGATVTGYVDIPSGDEEALKQAVATIGPISVAIDASSDSFQTYQDGIYDEPECSSVFLDHGVLAVGYGTED--GSDYWLVKNSWGTSWGIKGYIKMSRNKNNQCGIATQASYP 329
[Close]
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: si:dkey-26g8.5 (cathepsin L1-like [Source:NCBI gene;Acc:103028700])

HSP 1 Score: 327.791 bits (839), Expect = 3.211e-110
Identity = 165/337 (48.96%), Postives = 222/337 (65.88%), Query Frame = 1 
Query:   79 FIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGN-CQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGY---GVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            F+ +  L+  CF        +  Q  D+ W  +K+  +K Y E+ E  RR +WE+NL+ ++ HN+E+++G+H Y LG+NQF D++++EF      YR       + S   +   L++P  V+W +KGYVTPVK+Q +CGSCWAFS+TG++EGQ+F+KT KLVS SEQ LVDCS+  GN+GCNGG M+QAFQY+    GI+ E  YPYTA D   C+Y           + DI  G E  L + +A VGP+SV IDA + SFQ Y  GIY E++CSS +LDHGVL VGY   G DED G+KYW+VKNSW + WG NGYI M+KD+ N CGIA+ ASYP
Sbjct:    2 FLTLASLLALCFCTGFTAPSLDRQ-LDDHWKLWKSWHSKSYHEKEEGWRRLVWEKNLKKVELHNLEHSMGKHTYRLGMNQFADMTNEEFRQAMNGYRSNPNKKSKGSLFLEPSFLEVPKQVDWREKGYVTPVKDQARCGSCWAFSSTGALEGQHFRKTGKLVSLSEQNLVDCSRPEGNQGCNGGIMEQAFQYVKDNGGIDSEESYPYTAKDDQPCRYDPNFNSANDTGFVDIPSGEEHALMKAVAAVGPVSVAIDAGHESFQFYQSGIYYEKACSSEELDHGVLVVGYGFEGADED-GKKYWIVKNSWSEKWGQNGYIYMAKDRKNHCGIASAASYP 336
[Close]
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000047972.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000030.1:138766:150097:-1 gene:ENSAMXG00000038942.1 transcript:ENSAMXT00000047972.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 310.842 bits (795), Expect = 1.133e-103
Identity = 160/308 (51.95%), Postives = 201/308 (65.26%), Query Frame = 1 
Query:  172 EYKTKFNKVYDEE-NEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEF---LDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            E+K KF K Y  E  E  R+ IW  NL+ + +HN+  + G   + LG+N F D+ +QEF   L   +      K      F  K     +P++V+W  +GYVT VK+Q  CGSCWAFS+TG++EGQ FKKT  LVS SEQQLVDCS+SYGN GCNGG M  AF Y+M   G++ E+ YPY   D  C++++  V   C  YT I  GSEE+L E + TVGP+SV +DA   SFQ Y  GIYDE  CSSTQL+HGVLAVGYG    +G+ YWLVKNSW  SWG  GYI+MS++KNNQCGIAT A YP +
Sbjct:   26 EWKLKFGKSYSSEAEESQRKMIWMTNLKLVLEHNMLADQGLKSHRLGMNHFADMENQEFRKMLSRCLGSFDTTKIHNATKFTGKAGGAAVPDTVDWRTQGYVTEVKSQGLCGSCWAFSSTGALEGQMFKKTGSLVSLSEQQLVDCSESYGNNGCNGGLMSYAFNYVMNNGGLDTEASYPYEGQDSVCRFNQYSVGATCSGYTFISSGSEEELKEVVGTVGPVSVAVDA-EVSFQLYQSGIYDESDCSSTQLNHGVLAVGYG--SQNGKDYWLVKNSWSTSWGEAGYIRMSRNKNNQCGIATFALYPEV 330
[Close]
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ctsl.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023607])

HSP 1 Score: 309.686 bits (792), Expect = 4.502e-103
Identity = 156/305 (51.15%), Postives = 203/305 (66.56%), Query Frame = 1 
Query:  175 YKTKFNKVYDE-ENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIY---MKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYI-MKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            +K KF K+Y   E E  R+  W  N + +  HN+  + G   Y LG+  F D+ ++E+  ++   +      K+    +F ++     LP++V+W  KGYVT +K+Q  CGSCWAFS TGS+EGQ F+KT KLVS SEQQLVDCS  YGN GC GG MDQAF+YI    GI+ E  YPY A+DG+C++    V   C  + DI  G E+ L E +AT+GPISV IDA + SFQ Y  GIY+E  CSST+LDHGVLAVGYG   D+G+ YWLVKNSWG  WG  GYI+MS++++NQCGIATM+SYP
Sbjct:   29 WKLKFGKIYHSVEEESQRKLTWLTNRKLVLVHNMLADQGIKSYRLGMTFFADMDNKEYRKLFASCLGSFNRTKAHSATTFLRQTLRDPLPDTVDWRPKGYVTDIKDQKDCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNFGCGGGLMDQAFEYIKANKGIDTEDSYPYEAVDGDCRFKPDSVGATCTGFVDITSGDEKALQEAVATIGPISVAIDAGHSSFQLYESGIYNEPDCSSTELDHGVLAVGYGT--DNGKDYWLVKNSWGLDWGNKGYIQMSRNEDNQCGIATMSSYP 331
[Close]
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000042132.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023924])

HSP 1 Score: 306.99 bits (785), Expect = 4.595e-102
Identity = 158/339 (46.61%), Postives = 205/339 (60.47%), Query Frame = 1 
Query:   70 MMHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIY---MKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            M  F+ +  L+    A +I    + F         +K K  KVY+   E  R+  W  N + +  HN+  + G   Y LG+  F D+ +QE+  +    +      K+    SF ++     LPN+V+W  +GYVT VKNQ  CGSCWAFS TG++EGQ F+K   L+  SEQQLVDCS+ YGN GC+GG+M+QAFQY+    G++ E  YPY AM+G C+Y    V   C  Y DI  G E+ L E +ATVGP+SV ID  + SFQ Y  G+YDE  CS++ L H VLAVGYG   D G+ YWLVKNSWG  WG  GYIKMS++KNNQCGIAT ASYP
Sbjct:    1 MRVFLAVATLVAVVGAASISMEDLEFHA-------WKLKLGKVYNPAEESQRKITWLANRKLVLVHNMLADQGLKTYRLGMTHFADMDNQEYRQMLQGCLGSFNETKAPGASSFLRQAGGATLPNTVDWRTQGYVTEVKNQEMCGSCWAFSATGALEGQMFRKLGYLLPLSEQQLVDCSREYGNMGCSGGWMNQAFQYVKDNGGLDTEDSYPYEAMEGYCRYYPDAVGATCSGYVDISIGDEQALQEAVATVGPVSVAIDVGHYSFQLYQSGVYDEPDCSTSALGHAVLAVGYG--SDYGQDYWLVKNSWGTYWGDQGYIKMSRNKNNQCGIATAASYP 330
[Close]
BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000048039.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023924])

HSP 1 Score: 306.99 bits (785), Expect = 4.595e-102
Identity = 158/339 (46.61%), Postives = 205/339 (60.47%), Query Frame = 1 
Query:   70 MMHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIY---MKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            M  F+ +  L+    A +I    + F         +K K  KVY+   E  R+  W  N + +  HN+  + G   Y LG+  F D+ +QE+  +    +      K+    SF ++     LPN+V+W  +GYVT VKNQ  CGSCWAFS TG++EGQ F+K   L+  SEQQLVDCS+ YGN GC+GG+M+QAFQY+    G++ E  YPY AM+G C+Y    V   C  Y DI  G E+ L E +ATVGP+SV ID  + SFQ Y  G+YDE  CS++ L H VLAVGYG   D G+ YWLVKNSWG  WG  GYIKMS++KNNQCGIAT ASYP
Sbjct:    1 MRVFLAVATLVAVVGAASISMEDLEFHA-------WKLKLGKVYNPAEESQRKITWLANRKLVLVHNMLADQGLKTYRLGMTHFADMDNQEYRQMLQGCLGSFNETKAPGASSFLRQAGGATLPNTVDWRTQGYVTEVKNQEMCGSCWAFSATGALEGQMFRKLGYLLPLSEQQLVDCSREYGNMGCSGGWMNQAFQYVKDNGGLDTEDSYPYEAMEGYCRYYPDAVGATCSGYVDISIGDEQALQEAVATVGPVSVAIDVGHYSFQLYQSGVYDEPDCSTSALGHAVLAVGYG--SDYGQDYWLVKNSWGTYWGDQGYIKMSRNKNNQCGIATAASYP 330
[Close]
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011285.1 (pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gene:ENSPMAG00000010258.1 transcript:ENSPMAT00000011285.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 309.686 bits (792), Expect = 2.601e-104
Identity = 155/297 (52.19%), Postives = 200/297 (67.34%), Query Frame = 1 
Query:  193 KVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPI--VKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            K YD+  E  RR IWE+NL+ I  HN+E+++G+H + +G+N+F D++ +EF    +  R         R +        K P SV+W K+GYVT VK+Q  CGSCWAFSTTGS+EGQ+ +KT  LVS SEQ LVDCS + GN GC GG MD AF YI K  GI+ E+ YPYTA D NC+Y+ +        + DI  G+EE L   +A+VGP+S+GIDAS  SFQ Y+ GIY +  CS+  LDHGVL VGYGVD+D   K+W+VKNSWG  WG +GYI M++DK+N CGIAT ASYP
Sbjct:    1 KTYDQNEEGWRRMIWEKNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTKEEFQHTMLGLRGSNDTSKASRGATFMAPAFFKAPESVDWRKQGYVTDVKDQGDCGSCWAFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSAEGNNGCKGGLMDLAFTYIKKNGGIDSEASYPYTAKDENCKYNPKNKAAEDTGFVDIPSGNEEALKNAVASVGPVSIGIDASLESFQLYSSGIYSDSDCSN-NLDHGVLVVGYGVDDDE-RKFWIVKNSWGTKWGDHGYILMARDKDNLCGIATAASYP 295
[Close]
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006499.1 (pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 gene:ENSPMAG00000005817.1 transcript:ENSPMAT00000006499.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 302.368 bits (773), Expect = 6.346e-101
Identity = 154/336 (45.83%), Postives = 215/336 (63.99%), Query Frame = 1 
Query:   88 IILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEF---LDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGN-CQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            ++  ++   A   P   I     DE W  +K    K+Y+ + E  RR IWE+NL  I+ HN+E++LG+H + +G+N F D++++EF   ++ Y   +P    V + S     ++ + P +V+W  KG VT VK+Q +CGSCWAFSTTG++EGQ+ +K  +LVS SEQ LVDCS++ GN+GC GG MDQAFQY+    GI+ E+ YPYT  DG+ C Y  +        + D+  G E+ L   +A+VGP+SV IDAS+ SFQ Y  G+Y E  CSS  LDHGVL VGYGV    ++G+KYW+VKNSW   WG  GY+ M+++K N CGIAT ASYP
Sbjct:    7 LVPALLAVMASATP---IHDPMLDEEWGSWKGFHQKLYEPKQESWRRMIWEKNLNKIKIHNLEHSLGKHTWRMGMNHFGDMTNEEFRQKMNGYHGVQP--HKVSKGSTFLVPQNYEAPPTVDWRDKGLVTEVKDQGECGSCWAFSTTGALEGQHMRKVGQLVSLSEQNLVDCSRAEGNQGCGGGLMDQAFQYVKDNGGIDSEAAYPYTGTDGDKCHYDPKFNSANDTGFVDVTSGDEKALKIAVASVGPVSVAIDASHESFQFYQSGVYFEPDCSSQDLDHGVLVVGYGVKGTGENGKKYWIVKNSWSPKWGDEGYVLMARNKKNHCGIATAASYP 337
[Close]
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010475.1 (pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 gene:ENSPMAG00000009483.1 transcript:ENSPMAT00000010475.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 298.516 bits (763), Expect = 4.239e-100
Identity = 148/293 (50.51%), Postives = 194/293 (66.21%), Query Frame = 1 
Query:  205 EENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPI--VKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            +E E  RR IWE+NL+ I  HN+E+++G+H + +G+NQF+D++ +EF  + + +R         R +        + P SV+W K+GYVT +KNQ  CGSCW+FSTTGS+EGQ+ +KT  LVS SEQ LVDCS + GN GCNGG M  AF YI K  GI+ E  YPY      C+Y  +        Y +I +G EE L   +A+VGP+SV IDAS  SFQSY  GIY +  CS   +DH VL VGYGVDE  G+K+WLVKNSWG +WG  GY++M++D NN CGIATM+SYP
Sbjct:    1 QEEEGWRRIIWEKNLKRISVHNLEHSMGKHTWRMGMNQFSDMTGEEFQQVMLGFRGWNGTSKAPRGATFMAPAFFEAPESVDWRKQGYVTDIKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNHGCNGGLMINAFNYIKKNGGIDSEESYPYKGQVETCKYDPKNKAAEVTGYVEIPEGDEEALMNAVASVGPVSVAIDASLASFQSYGSGIYKDAMCSH-HIDHAVLVVGYGVDE-MGQKFWLVKNSWGVTWGEQGYVRMARDDNNLCGIATMSSYP 291
[Close]
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003800.1 (pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 gene:ENSPMAG00000003453.1 transcript:ENSPMAT00000003800.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 277.715 bits (709), Expect = 7.313e-92
Identity = 142/288 (49.31%), Postives = 187/288 (64.93%), Query Frame = 1 
Query:  223 RRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPI--VKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMD-GNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            RR IWE+NL+ I  HN+E+++G+H + +G+N+F D++ +EF  + + +R         R +        + P SV+W K+GYVT VKNQ  CGSCW+FSTTGS+EGQ+ +KT  LVS SEQ LVDCS + GN GCNGG M  AF YI K  GI+ E  YPY       C+Y+ +        Y +I +G EE L   +A+VGP+SV IDAS  SF  Y  GIY ++ CS   ++H VL VGYGVDE  G+K+WLVKNSWG  WG  GY++M++D NN CGIA  ASYP
Sbjct:    8 RRMIWEQNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTGEEFQQVMLGFRGWNGTSKAPRGATFMAPAFFEAPESVDWRKQGYVTDVKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNYGCNGGLMINAFNYIKKNGGIDSEESYPYKGQGVETCKYNPKNKAAEVTGYVEIPEGDEEALKNAVASVGPVSVAIDASLNSFLYYISGIYKDKLCSHI-INHAVLVVGYGVDE-KGDKFWLVKNSWGVQWGEKGYVRMARDDNNLCGIAVTASYP 293
[Close]
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008535.1 (pep scaffold:Pmarinus_7.0:GL478103:36116:54424:1 gene:ENSPMAG00000007699.1 transcript:ENSPMAT00000008535.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 277.715 bits (709), Expect = 3.812e-91
Identity = 140/310 (45.16%), Postives = 197/310 (63.55%), Query Frame = 1 
Query:  151 GFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSL-----KLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMD-GNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD--EDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGI 1053
              D  W  +   F K Y + +   RR IWEEN++F+ +HN+E++LG H YTLG+N   DL+  EF      YR    S ER         L     ++P S++W  +G VTP+KNQ QCGSCWAFS+TG++EGQ+ +++ +LV  SEQ L+DCS+  G EGC GG+MD AFQY++ + GI+ ES YPYTA D  +C Y   +++ R   + DI +GSE+DL   +A+VGP+SV IDA + SFQ Y  GIY E  C+ T+LDH VL VG+GV    ++G+K+W+VKN  G   G   Y++++ DK   CG+
Sbjct:   31 ALDGHWEAWTVYFKKAYTQTDGIKRRLIWEENMRFVDRHNLEHSLGLHSYTLGMNHLADLTVDEFRKTMNGYRR--GSRERHEGHHTSTFLAPENYEVPQSMDWRDQGLVTPIKNQGQCGSCWAFSSTGALEGQWKRRSGELVPLSEQNLLDCSRPEGTEGCGGGWMDDAFQYVLDQGGIDSESDYPYTATDVDSCHYDPSRMVARISGFVDIHKGSEKDLITAVASVGPVSVAIDAGHQSFQLYESGIYYEPECNCTELDHAVLVVGFGVKGRGENGKKFWIVKNRRGLQCGGEIYLEVAVDKRCFCGL 338
[Close]
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO46465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPY5])

HSP 1 Score: 347.436 bits (890), Expect = 1.878e-118
Identity = 176/332 (53.01%), Postives = 216/332 (65.06%), Query Frame = 1 
Query:   82 IRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            + + +LI  CF+E            D  W  +K    K Y  E E +RR IW +NL+ ++KHN E     H Y L +N F DL+  EF   +M YR    S    +F     +++LP  V+W  KG+VT VKNQ QCGSCWAFS+TGS+EGQ+F+KT KLVS SEQ LVDCS+ YGN GC GG MD AF+YI    GI+ E  YPYTA DG C +    V      YTD+ +GSE DL   +ATVGPISV IDA + SFQ Y  G+Y E  CSSTQLDHGVLAVGYG ++  G+ YWLVKNSWG+ WG+NGYIKMS++K+NQCGIAT ASYP
Sbjct:    8 LLVAVLIAQCFSELSQ---------DRQWHAWKDFHGKTYTGEEEDLRRAIWNDNLEIVKKHNAE----NHSYKLDMNHFADLTVTEFKQRFMGYRAASNSTGGSTF-LPLSNVQLPAEVDWRDKGFVTAVKNQGQCGSCWAFSSTGSLEGQHFRKTGKLVSLSEQNLVDCSKKYGNNGCEGGLMDYAFKYIKNNDGIDTEQSYPYTARDGQCHFKPGSVGATVTGYTDVQRGSEGDLQSAVATVGPISVAIDAGHSSFQLYKTGVYSEPDCSSTQLDHGVLAVGYGAED--GKDYWLVKNSWGEGWGMNGYIKMSRNKDNQCGIATQASYP 323
[Close]
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO45953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRH6])

HSP 1 Score: 321.242 bits (822), Expect = 2.849e-108
Identity = 169/334 (50.60%), Postives = 216/334 (64.67%), Query Frame = 1 
Query:   82 IRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVY-DEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERK-SFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYI-MKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            +++ L++    A +  WS  F Q  D  W  +K+   K Y D   E  R  IW++NL+ I++HN E     H Y + +N   DL+  EF   Y+  R    S +R  +      ++K+P+SV+W +KGYVT VKNQ QCGSCWAFSTTGS+EGQ+F+KT  LVS SEQ L+DCS SYGN GC GG MD AF+YI    GI+ ES YPY    G+C +S   V  R   Y DI QGSE+ L   +ATVGP+SV +DAS   +Q Y+ G+YD   CSSTQLDHGVL +GYG    +G+ YWLVKNSWG SWG+ GYI MS++KNNQCGIA+ ASYP
Sbjct:    1 MKVFLVLCVLVASSRGWSVRFGQ--DSEWVAWKSYHGKSYSDVHEERTRMAIWQQNLEKIKRHNAE----DHSYKMAMNHLGDLTEDEFRYFYLGVRAHHNSTKRGWATYMPPSNVKIPSSVDWSQKGYVTGVKNQGQCGSCWAFSTTGSVEGQHFRKTGSLVSLSEQNLIDCSGSYGNNGCQGGLMDNAFRYIESNGGIDTESSYPYLGQQGSCHFSSSHVGARVTGYQDIPQGSEQALQSAVATVGPVSVAVDASQ--WQFYSSGVYDNPYCSSTQLDHGVLVIGYG--NYNGQDYWLVKNSWGYSWGVEGYIMMSRNKNNQCGIASSASYP 324
[Close]
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO36727 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHX1])

HSP 1 Score: 311.227 bits (796), Expect = 3.120e-104
Identity = 168/334 (50.30%), Postives = 207/334 (61.98%), Query Frame = 1 
Query:   94 LLIVPCFAETIPWSGIFFQGFDE---LWSEYKTKFNKVYDE-ENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERK--SFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            LL+  C    +  SG F   FDE    W  +K    K Y     E  R+ IW +NL+ IQKHN E     H +TL +N   DL+  EF   Y   R    +  +K  S       +++P++V+W K+GYVTPVKNQ QCGSCWAFSTTGS+EGQ FKKT KLVS SEQ LVDCS +YGN GC GG MD AF+YI +  GI+ E  YPY A +  C++ K  +      + D+  G EE L     TVGPISV IDA + SFQ Y+ G+Y+   CSST LDHGVL VGYG  +  G  YWLVKNSWG+ WG+ GYI MS++KNNQCG+AT ASYP
Sbjct:    3 LLVAACLLFAVA-SG-FVVKFDEDEQQWQAWKLFHTKKYTTVTEEGARKAIWRDNLKKIQKHNAE----GHSFTLAMNHLGDLTQDEFRYFYTGMRSHYSNYTKKQGSAFLAPSHVQVPDTVDWRKEGYVTPVKNQGQCGSCWAFSTTGSLEGQNFKKTGKLVSLSEQNLVDCSTAYGNNGCQGGLMDYAFKYIKENGGIDTEESYPYEARNDRCRFQKSNIGAVDTGFVDVTHGDEEALKTAAGTVGPISVAIDAGHMSFQFYHSGVYNNAGCSSTSLDHGVLVVGYGTYQ--GSDYWLVKNSWGERWGMEGYIMMSRNKNNQCGVATQASYP 328
[Close]
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO45852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL9])

HSP 1 Score: 301.597 bits (771), Expect = 1.726e-100
Identity = 153/310 (49.35%), Postives = 204/310 (65.81%), Query Frame = 1 
Query:  157 DELWSEYKTKFNKVYDEENEFVRRQ-IWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLD--IYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            D  W  +K+   K Y  +NE   R  IW+ NL+ I  HN     G+H + L +N   D++  E     + +K +   +S  + +      ++K+ +S++W  KGYVTPVKNQ QCGSCWAFSTTG++EGQ+F+KT KLVS SEQ LVDCS  YGN GC GG MD AFQYI +  GI+ E  YPY A DG C Y+K  +  +   + DI  G E  L + LA+VGPIS+ IDAS  +F  Y+ G+YD+  CSST+LDHGVLAVGYG D+  G+ YWLVKNSWG SWG  GYIK++++ +++CG+A+ ASYP
Sbjct:   26 DPNWKAWKSFHGKEYPNKNEETMRNFIWQNNLKKIVTHN----EGKHSFKLAMNHLGDMTSLEISQTLLGLKLKKHAESQPKGATFLPPANVKVVDSIDWRSKGYVTPVKNQGQCGSCWAFSTTGALEGQHFRKTGKLVSLSEQNLVDCSGKYGNNGCEGGLMDNAFQYIKENGGIDTEKSYPYLAKDGVCHYNKSAIGAKDTGFVDIPTGDENALQQALASVGPISIAIDASQSTFHFYHQGVYDDPDCSSTRLDHGVLAVGYGTDD--GKDYWLVKNSWGPSWGEEGYIKIARNDHDKCGVASKASYP 329
[Close]
BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO41322 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4P4])

HSP 1 Score: 213.001 bits (541), Expect = 1.236e-63
Identity = 125/321 (38.94%), Postives = 175/321 (54.52%), Query Frame = 1 
Query:  160 ELWSEYKTKFNKVY-DEENEFVRRQIWEENLQFIQKHNIEYNLGRHK-YTLGVNQFTDLSHQEFLDIY-----------MKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFG--IEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQ--LDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASY 1071
             ++ +Y  K  K Y D +    RR+ ++ NL+FI   N      RH  Y L +N   D S +E   +            + Y+P + S+             +P+ +NWV +G VTPVK+Q  CGSCW+F TTG++EG  F KT+ L   S+Q L+DCS   GN  C+GG   +++QYIMK G    +ES  PY   DG C     ++      Y +I +G    L   +A  GPISV IDAS+ S   Y+ G+Y E  C +    LDH VLAVGYG  +  G+ YW++KNSW   WG+NGY+ MS+ K+N CG+AT A+Y
Sbjct:  243 RVFDKYVKKHKKNYKDNKEHHTRREHFKHNLRFIHSKN-----RRHAGYYLAMNHLGDRSDKELRVLRGRRYTKGYNGGLPYKPDMASIN-----------DVPDEMNWVIRGAVTPVKDQAVCGSCWSFGTTGTIEGTLFLKTKYLTRLSQQNLMDCSWGEGNNACDGGEDFRSYQYIMKSGGIATEESYGPYLGADGYCHKKDAEIGATITGYVNITEGDLSALKTAIAQKGPISVSIDASHKSLSFYSYGVYYEPKCGNKNEDLDHSVLAVGYGTMD--GKPYWMIKNSWSTHWGMNGYVLMSQ-KDNNCGVATAATY 544
[Close]
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsl (cathepsin L [Source:NCBI gene;Acc:100049246])

HSP 1 Score: 319.701 bits (818), Expect = 4.482e-107
Identity = 161/311 (51.77%), Postives = 210/311 (67.52%), Query Frame = 1 
Query:  154 FDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGN-CQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVD-ED-SGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
             D+ W  +K   +K Y E+ E  RR +WE+NL+ I+ HN+E+++G+H Y LG+N F D++H+EF  I   Y+   +     S   +   L+ P +V+W  KGYVTPVK+Q QCGSCWAFSTTG++EGQ F+KT KLVS SEQ LVDCS+  GNEGCNGG MDQAFQY+    G++ E  YPY   D   CQY+ +        + DI  G E  L + +A+VGP+SV IDA + SFQ Y  GIY E+ CSS +LDHGVL VGYG + ED  G+KYW+VKNSW + WG  G+I M+KD++N CGIAT ASYP
Sbjct:   24 LDQHWQLWKGWHSKNYHEKEEGWRRLVWEKNLRKIELHNLEHSMGKHSYRLGMNHFGDMTHEEFRQIMNGYKRREQRKYSGSLFMEPNFLEAPRAVDWRDKGYVTPVKDQGQCGSCWAFSTTGALEGQQFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDNQGLDSEDFYPYKGTDDQPCQYNAQYSAVNDTGFVDIPSGKERALMKAVASVGPVSVAIDAGHESFQFYQSGIYFEKECSSDELDHGVLVVGYGFEGEDVDGKKYWIVKNSWSEKWGDKGFIYMAKDRHNHCGIATAASYP 334
[Close]
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsl.1 (cathepsin L1 [Source:NCBI gene;Acc:101171789])

HSP 1 Score: 314.694 bits (805), Expect = 4.584e-105
Identity = 162/306 (52.94%), Postives = 203/306 (66.34%), Query Frame = 1 
Query:  175 YKTKFNKVYDEENEFV-RRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMK--YRPIVKSVERK--SFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            ++ KF + Y    E   RRQ W  N + +  HNI  + G   Y LG+  F D+ ++E+  +  +        S+ R+  +F +  ++  LP +V+W  KGYVT VK+Q QCGSCWAFS TGS+EGQ F+KT KLVS SEQQLVDCS  YGN GC GG MD AF+YI    GI+ E  YPY A DG C+Y    V   C  Y D+  G E+ L E +AT+GPISVGIDAS+ SFQ Y  G+YDE  CSS++LDHGVLAVGYG   ++G+ YWLVKNSWG +WG  GYIKMSK+K+NQCGIAT ASYP
Sbjct:   34 WRLKFGRTYSSPTEEAQRRQTWLNNRKLVLVHNILADQGIKSYRLGMTYFADMENEEYKRLISQGCLGSFNASLPRRGSTFFRLPENKDLPAAVDWRDKGYVTDVKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNMGCGGGLMDDAFRYIQATGGIDTEESYPYEAEDGECRYKPDAVGATCTGYVDVSSGDEDALQEAVATIGPISVGIDASHISFQLYESGLYDEPQCSSSELDHGVLAVGYG--SENGQDYWLVKNSWGLTWGDQGYIKMSKNKSNQCGIATAASYP 337
[Close]
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctss2.1 (cathepsin S [Source:NCBI gene;Acc:101165175])

HSP 1 Score: 291.197 bits (744), Expect = 6.749e-96
Identity = 148/314 (47.13%), Postives = 191/314 (60.83%), Query Frame = 1 
Query:  142 FFQGFDELWSEYKTKFNKVYDEENEFV-RRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVK-SVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIM-KFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            F    D  W  +K   +K Y  E E V RR +WE NL  I  HN+EY++G H Y L +N   DL+ +E L  +   RP      E   F     S  +P+ ++W +K  VT VK Q  CGSCWAFS  G++EGQ  +KT KLV  S Q LVDCS  YGN GCNGGFM QAFQY++   GI+ ++ YPY  +  NC YS       C  Y+ + +G E  L E +AT+GPISV IDA+ P F  Y  G+YD+ SCS   ++HGVLAVGYG    +G+ YWLVKNSWG ++G  GYI+M+++KN+QCGIA    YP
Sbjct:   27 FDSRLDIHWELWKKTHSKHYPSEEEDVHRRDLWERNLMLITMHNLEYSMGLHTYDLSMNHMGDLTQEEILQQFASLRPPTNLKREPHLFVGASGSNNIPDEMDWRQKNCVTSVKMQGSCGSCWAFSAVGALEGQLCRKTGKLVDLSPQNLVDCSSKYGNHGCNGGFMHQAFQYVIDNQGIDSDAGYPYVGVTQNCHYSSEYRAANCSQYSFLPEGDEGALKEAIATIGPISVAIDATRPRFAFYRSGVYDDSSCSQN-VNHGVLAVGYGT--LNGQDYWLVKNSWGTTFGEQGYIRMARNKNDQCGIAMYGCYP 337
[Close]
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctss (cathepsin S [Source:NCBI gene;Acc:100049247])

HSP 1 Score: 284.263 bits (726), Expect = 2.745e-93
Identity = 144/310 (46.45%), Postives = 192/310 (61.94%), Query Frame = 1 
Query:  154 FDELWSEYKTKFNKVYDEE-NEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFL-DIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
             D+ W+ +K  ++K Y  E  EF RR+IWEENL+ I  HN+E +LG H Y L +N   DL+ +E +  +     P+   +ER  +D  + +  +P SV+W + G VT VK Q +CGSCWAFS  G++EGQ  K T  L S S Q LVDCS  YGN GC GGFM  AFQY++K  GI  ++ YPY      C+Y  +     C  Y  + +G E  L   +AT+GPISV IDAS P F  Y  G+Y + SCS   ++HGVL VGYG   ++GE YWLVKNSWG+ +G  GYIKM++++ NQCGIA  A +P
Sbjct:   21 LDQHWNLWKKTYSKTYSHEIEEFGRRRIWEENLEMISVHNLEVSLGLHSYELAMNHLGDLTIEELIASLTGTVAPV--GLERIHYDLVKINTSVPESVDWREGGLVTSVKTQGRCGSCWAFSAVGALEGQLKKTTGILTSLSPQNLVDCSTKYGNYGCKGGFMSNAFQYVIKNQGISSDAAYPYIGKRDKCKYDSKHRAANCTGYNFLPKGDEFALKVGVATIGPISVAIDASRPKFLFYRHGVYKDHSCSH-NVNHGVLVVGYGT--ENGEDYWLVKNSWGERYGDGGYIKMARNRRNQCGIALYACFP 325
[Close]
BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsk (cathepsin K [Source:NCBI gene;Acc:101164922])

HSP 1 Score: 283.878 bits (725), Expect = 3.832e-93
Identity = 142/309 (45.95%), Postives = 194/309 (62.78%), Query Frame = 1 
Query:  154 FDELWSEYKTKFNKVY-DEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMK-FGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
             D  W E+K    K Y   E E +RR IWE+NL+ I+ HN E  LG H YTLG+NQF D++ +E ++     +  +    R   +     +KLP SV++ KKG VT VKNQ  CGSCWAFS+ G++EGQ  KKT  LV  S Q LVDC     N+GC GG+M  AF+Y+ +  GI+ E+ YPY   D  C+Y+   +  + K Y ++ +G E  LA  L   GP+SVGIDAS  SF  Y  GIY + +C+   ++H VLAVGYGV+   G+K+W+VKNSWG++WG  GY+ M++++ N CGIA +ASYP
Sbjct:   24 LDAHWEEWKMTHTKEYITVEEEGIRRAIWEKNLRMIEAHNQEAALGMHTYTLGMNQFGDMTQEEVVERMTGLQMPLNPEPRVPMETDGSLIKLPKSVDYRKKGMVTSVKNQGSCGSCWAFSSVGALEGQLAKKTGNLVDLSPQNLVDCVTE--NDGCGGGYMTNAFKYVQENGGIDSEAAYPYMGEDQPCRYNVSGLAAQIKGYKEVPEGDEHALAVALFKAGPVSVGIDASQNSFLYYQKGIYFDRNCNKEDINHAVLAVGYGVNA-KGKKFWIVKNSWGETWGNKGYVLMARNRGNVCGIANLASYP 329
[Close]
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049716.1 (SMESG000049716.1)

HSP 1 Score: 704.131 bits (1816), Expect = 0.000e+0
Identity = 337/337 (100.00%), Postives = 337/337 (100.00%), Query Frame = 1 
Query:   70 MMHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            MMHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL
Sbjct:    1 MMHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 337
[Close]
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049716.1 (SMESG000049716.1)

HSP 1 Score: 702.205 bits (1811), Expect = 0.000e+0
Identity = 336/336 (100.00%), Postives = 336/336 (100.00%), Query Frame = 1 
Query:   73 MHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 1080
            MHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL
Sbjct:    1 MHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL 336
[Close]
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049722.1 (SMESG000049722.1)

HSP 1 Score: 402.905 bits (1034), Expect = 5.863e-140
Identity = 189/334 (56.59%), Postives = 249/334 (74.55%), Query Frame = 1 
Query:   82 IRIILLIVPCFAETIPWSGIFFQ---GFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            ++I+LL V C   +I    + F+     +E W+ YK +F + Y+   E  RR IWEENL+ IQKHNIEY+LG+H Y LG+N+F D++++E+    +  +PI K+  R  F     ++ LP SV+W  KGYVTPVKNQ  CGSCW+FSTTGS+EGQ+ +KT +L+S SEQQLVDCS+ +GN GCNGG MD AFQYI K+G+E E+ Y YTA +GNC+Y   KV+  C  + DI +G+E+DLA+ +ATVGPISV IDAS P+FQ Y GGIY+E+SCSS QLDHGVLAVGYG  +++ + +W+VKNSWG  WGL+GYIKM+KD++NQCGIATMASYP
Sbjct:    1 MKIVLLAVFCVV-SISAGKLKFEVNEALNEEWNMYKIQFQRKYESIIELTRRLIWEENLRLIQKHNIEYDLGKHSYYLGLNEFADMTNEEYRVKVLGLKPINKNYTRTIFLAPENTVDLPKSVDWRTKGYVTPVKNQANCGSCWSFSTTGSLEGQHKRKTGQLISLSEQQLVDCSKPFGNNGCNGGLMDNAFQYIQKYGLESEADYSYTAKEGNCKYDASKVVAHCTGFVDIKKGNEKDLAKAVATVGPISVAIDASKPTFQLYKGGIYNEKSCSSRQLDHGVLAVGYG--KENNQHFWIVKNSWGPQWGLSGYIKMTKDRHNQCGIATMASYP 331
[Close]
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049723.1 (SMESG000049723.1)

HSP 1 Score: 396.356 bits (1017), Expect = 2.142e-137
Identity = 192/332 (57.83%), Postives = 242/332 (72.89%), Query Frame = 1 
Query:   91 ILLIVPCFAETIPWSGIFFQGFDEL---WSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKS-FDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            I+++V  F   +  +   F    EL   W  YKT+F K Y   NE  RR IWE+NL++IQ+HN+E++LG+H YTLG+N F D++++EF   Y+   P  K +   S F        LP+SV+W  KG+VTPVKNQ QCGSCW+FSTTGS+EGQ+++KT+ L+SFSEQQLVDCS S+GN GC+GG MD AFQYI ++GIE ES YPYTA DGNC Y K KV+  C  ++DI  G+E+ LA  +ATVGPISV IDASN SFQ Y  GIY+E  CSS+QLDHGVLA+GYG   ++G+ +WLVKNSWG  WG+ GYIKMSKD+ NQCGIATMASYP
Sbjct:    3 IIILVSLFLAAVSAAPQQFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVSP--KRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGT--ENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGIATMASYP 330
[Close]
BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000014167.1 (SMESG000014167.1)

HSP 1 Score: 390.963 bits (1003), Expect = 3.315e-135
Identity = 189/335 (56.42%), Postives = 238/335 (71.04%), Query Frame = 1 
Query:   70 MMHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFGIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYP 1074
            M  F+ I + +V   A    +S       ++ W  YKT+F + Y+   E  RR IWE+NL++I++HN+EY+LG+H Y LG+N++ DL+++EF   ++       S +   F        LP +V+W  KGYVTPVKNQ QCGSCWAFSTTGS+EGQ+F+KT  LVSFSEQQLVDCS +YGNEGC GG MD AF YIMK+G+E E  YPYTA DG C+Y + KV+  C  +TDI  G+E DLA  +ATVGP+SV IDAS+ SFQ Y GGIY+E  CS  QLDHGVLAVGYG   ++G  YWLVKNSWG SWGL+GYIKMSKD+NNQCGI+T AS+P
Sbjct:    1 MKAFVLISVFLVAIQARRPTFS--LNSELNKDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSRKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYG--SENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFP 331
The following BLAST results are available for this feature:
BLAST of Cathepsin L2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CTSV3.527e-11048.08cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538][more]
CTSV3.527e-11048.08cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538][more]
CTSL1.391e-10246.99cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537][more]
CTSL1.391e-10246.99cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537][more]
CTSS5.982e-9647.44cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545][more]
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BLAST of Cathepsin L2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cpl-17.828e-9446.25CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
cpl-12.114e-7556.12CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
cpl-12.114e-7556.12CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
tag-1962.887e-5239.69pep chromosome:WBcel235:V:8594914:8597500:1 gene:W... [more]
tag-1962.887e-5239.69pep chromosome:WBcel235:V:8594914:8597469:1 gene:W... [more]
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BLAST of Cathepsin L2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cp12.606e-10149.84gene:FBgn0013770 transcript:FBtr0087593[more]
Cp13.655e-10149.84gene:FBgn0013770 transcript:FBtr0087592[more]
Cp12.750e-10047.45gene:FBgn0013770 transcript:FBtr0339955[more]
Cp14.868e-8958.90gene:FBgn0013770 transcript:FBtr0304021[more]
CG63474.560e-6635.38gene:FBgn0033874 transcript:FBtr0087637[more]
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BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-269i1.47.807e-11248.36si:dkey-269i1.4 [Source:ZFIN;Acc:ZDB-GENE-121214-3... [more]
si:dkey-239j18.22.883e-11048.97si:dkey-239j18.2 [Source:ZFIN;Acc:ZDB-GENE-121214-... [more]
si:dkey-239j18.22.883e-11048.97si:dkey-239j18.2 [Source:ZFIN;Acc:ZDB-GENE-121214-... [more]
si:dkey-269i1.44.913e-11047.76si:dkey-269i1.4 [Source:ZFIN;Acc:ZDB-GENE-121214-3... [more]
ctslb7.110e-11047.76cathepsin Lb [Source:ZFIN;Acc:ZDB-GENE-980526-285][more]
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BLAST of Cathepsin L2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fcrl28.639e-10651.12Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590... [more]
fcrl21.365e-10548.22Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590... [more]
ano17.750e-9444.44anoctamin 1, calcium activated chloride channel [S... [more]
harbi11.242e-9245.11harbinger transposase derived 1 [Source:Xenbase;Ac... [more]
ctsk8.122e-8844.01cathepsin K (pycnodysostosis) [Source:NCBI gene;Ac... [more]
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BLAST of Cathepsin L2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ctsl4.282e-10650.32cathepsin L [Source:MGI Symbol;Acc:MGI:88564][more]
Ctsl4.282e-10650.32cathepsin L [Source:MGI Symbol;Acc:MGI:88564][more]
Ctsll37.758e-10247.88cathepsin L-like 3 [Source:MGI Symbol;Acc:MGI:1917... [more]
BC0516651.154e-9946.11cDNA sequence BC051665 [Source:MGI Symbol;Acc:MGI:... [more]
4930486L24Rik1.352e-9544.78RIKEN cDNA 4930486L24 gene [Source:MGI Symbol;Acc:... [more]
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BLAST of Cathepsin L2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O60911|CATL2_HUMAN1.694e-10948.08Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 ... [more]
sp|P07154|CATL1_RAT1.739e-10650.32Cathepsin L1 OS=Rattus norvegicus OX=10116 GN=Ctsl... [more]
sp|P06797|CATL1_MOUSE2.995e-10550.32Cathepsin L1 OS=Mus musculus OX=10090 GN=Ctsl PE=1... [more]
sp|Q9GKL8|CATL1_CHLAE3.228e-10249.05Cathepsin L1 OS=Chlorocebus aethiops OX=9534 GN=CT... [more]
sp|P07711|CATL1_HUMAN6.680e-10246.99Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 ... [more]
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BLAST of Cathepsin L2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2U8U4473.796e-13357.36Cathepsin L2 OS=Dugesia japonica OX=6161 PE=2 SV=1[more]
A0A0B5ITX63.041e-12153.12Cathepsin L3 OS=Nephilengys cruentata OX=450950 PE... [more]
A0A0L8HPF99.040e-12153.55Uncharacterized protein OS=Octopus bimaculoides OX... [more]
W4YG811.706e-11853.01Uncharacterized protein OS=Strongylocentrotus purp... [more]
A0A4Y2RKW01.618e-11752.84Cathepsin L OS=Araneus ventricosus OX=182803 GN=CA... [more]
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BLAST of Cathepsin L2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-26g8.53.211e-11048.96cathepsin L1-like [Source:NCBI gene;Acc:103028700][more]
ENSAMXT00000047972.11.133e-10351.95pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ctsl.14.502e-10351.15cathepsin L1-like [Source:NCBI gene;Acc:103023607][more]
ENSAMXT00000042132.14.595e-10246.61cathepsin L1-like [Source:NCBI gene;Acc:103023924][more]
ENSAMXT00000048039.14.595e-10246.61cathepsin L1-like [Source:NCBI gene;Acc:103023924][more]
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BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000011285.12.601e-10452.19pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gen... [more]
ENSPMAT00000006499.16.346e-10145.83pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 g... [more]
ENSPMAT00000010475.14.239e-10050.51pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 ... [more]
ENSPMAT00000003800.17.313e-9249.31pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 g... [more]
ENSPMAT00000008535.13.812e-9145.16pep scaffold:Pmarinus_7.0:GL478103:36116:54424:1 g... [more]
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BLAST of Cathepsin L2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cathepsin L2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO464651.878e-11853.01Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459532.849e-10850.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO367273.120e-10450.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO458521.726e-10049.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO413221.236e-6338.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cathepsin L2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsl4.482e-10751.77cathepsin L [Source:NCBI gene;Acc:100049246][more]
ctsl.14.584e-10552.94cathepsin L1 [Source:NCBI gene;Acc:101171789][more]
ctss2.16.749e-9647.13cathepsin S [Source:NCBI gene;Acc:101165175][more]
ctss2.745e-9346.45cathepsin S [Source:NCBI gene;Acc:100049247][more]
ctsk3.832e-9345.95cathepsin K [Source:NCBI gene;Acc:101164922][more]
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BLAST of Cathepsin L2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000049716.10.000e+0100.00SMESG000049716.1[more]
SMESG000049716.10.000e+0100.00SMESG000049716.1[more]
SMESG000049722.15.863e-14056.59SMESG000049722.1[more]
SMESG000049723.12.142e-13757.83SMESG000049723.1[more]
SMESG000014167.13.315e-13556.42SMESG000014167.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023605 ID=SMED30023605|Name=Cathepsin L2|organism=Schmidtea mediterranea sexual|type=transcript|length=1230bp
ATTTGATGCACATGACTCTCGCGTGAACGAAGGTGAATATAACAAACGAT
AATTTTGACAAATTTCACAATGATGCATTTTATTAGAATAATATTATTAA
TCGTTCCGTGTTTTGCAGAAACCATACCGTGGTCAGGTATTTTCTTTCAA
GGATTCGATGAGCTATGGAGTGAATACAAAACCAAGTTTAATAAAGTTTA
TGATGAAGAGAATGAGTTTGTTCGAAGGCAAATTTGGGAGGAAAATCTGC
AATTTATTCAAAAGCACAATATTGAATACAACTTAGGGAGACACAAATAC
ACGTTGGGAGTCAATCAGTTTACGGACTTGAGCCATCAGGAGTTTTTAGA
TATTTATATGAAATATCGTCCAATTGTGAAATCTGTTGAAAGGAAATCCT
TTGACAAGAAACGAAAGTCATTGAAATTGCCCAATAGTGTGAACTGGGTA
AAAAAAGGTTACGTCACACCTGTCAAAAATCAACTACAATGCGGCTCTTG
TTGGGCATTCTCTACGACAGGGTCAATGGAAGGACAATACTTCAAGAAAA
CAAGAAAATTAGTCAGTTTTTCTGAACAGCAACTTGTTGACTGTAGTCAA
AGCTATGGCAATGAAGGTTGTAATGGTGGTTTCATGGATCAAGCCTTTCA
ATACATTATGAAATTTGGAATTGAGAAGGAAAGTGTTTATCCATATACTG
CCATGGATGGAAATTGCCAATATTCCAAACGCAAAGTTATTACGCGGTGT
AAGAACTATACCGACATTGACCAAGGAAGTGAGGAAGATTTGGCTGAAAA
ATTAGCAACAGTTGGACCAATATCTGTTGGAATTGATGCCAGCAATCCTA
GTTTCCAGTCTTATAATGGAGGAATTTACGATGAAGAAAGCTGTTCATCA
ACTCAGCTTGATCATGGTGTTTTAGCAGTTGGATATGGAGTCGACGAAGA
TTCGGGAGAAAAGTATTGGTTAGTGAAAAACAGTTGGGGAGATTCTTGGG
GACTTAATGGATATATAAAGATGTCAAAGGATAAGAATAATCAATGTGGA
ATAGCTACCATGGCCAGTTACCCTAACCTTTGAGTAACAATAACATAATT
TGAATACTTTTAATGAATTTATTGTCTGTTAAATGAAACTATTAATATCG
TTTTTATTATTATACTTTGCGAATTTGAAGTAAACTATTCACACGATCAC
TATCCATGTATCATATACGATTCATAATTA
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protein sequence of SMED30023605-orf-1

>SMED30023605-orf-1 ID=SMED30023605-orf-1|Name=SMED30023605-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=338bp
MMHFIRIILLIVPCFAETIPWSGIFFQGFDELWSEYKTKFNKVYDEENEF
VRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYR
PIVKSVERKSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTT
GSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKFG
IEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGP
ISVGIDASNPSFQSYNGGIYDEESCSSTQLDHGVLAVGYGVDEDSGEKYW
LVKNSWGDSWGLNGYIKMSKDKNNQCGIATMASYPNL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000028Category 2 cell
PLANA:0000240body wall musculature
PLANA:0002142parenchyma
PLANA:0003116parenchymal cell
PLANA:0007528glial cell
Vocabulary: INTERPRO
TermDefinition
IPR039417Peptidase_C1A_papain-like
IPR038765Papain-like_cys_pep_sf
IPR000668Peptidase_C1A_C
IPR013201Prot_inhib_I29
IPR000169Pept_cys_AS
IPR025660Pept_his_AS
IPR025661Pept_asp_AS
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
Vocabulary: molecular function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO:0008233peptidase activity
GO:0016787hydrolase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000668Peptidase C1A, papain C-terminalPRINTSPR00705PAPAINcoord: 282..292
score: 60.52
coord: 299..305
score: 75.76
coord: 138..153
score: 59.4
IPR000668Peptidase C1A, papain C-terminalSMARTSM00645pept_c1coord: 120..336
e-value: 1.2E-116
score: 403.5
IPR000668Peptidase C1A, papain C-terminalPFAMPF00112Peptidase_C1coord: 120..335
e-value: 1.3E-81
score: 273.9
IPR013201Cathepsin propeptide inhibitor domain (I29)SMARTSM00848Inhibitor_I29_2coord: 33..92
e-value: 4.0E-24
score: 96.1
IPR013201Cathepsin propeptide inhibitor domain (I29)PFAMPF08246Inhibitor_I29coord: 33..92
e-value: 4.7E-13
score: 49.4
NoneNo IPR availableGENE3DG3DSA:3.90.70.10coord: 27..337
e-value: 6.2E-115
score: 386.0
NoneNo IPR availablePANTHERPTHR12411:SF631coord: 27..335
NoneNo IPR availablePANTHERPTHR12411CYSTEINE PROTEASE FAMILY C1-RELATEDcoord: 27..335
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..16
score: 0.853
NoneNo IPR availableTMHMMTMhelixcoord: 7..29
IPR025661Cysteine peptidase, asparagine active sitePROSITEPS00640THIOL_PROTEASE_ASNcoord: 299..318
IPR000169Cysteine peptidase, cysteine active sitePROSITEPS00139THIOL_PROTEASE_CYScoord: 138..149
IPR025660Cysteine peptidase, histidine active sitePROSITEPS00639THIOL_PROTEASE_HIScoord: 280..290
IPR039417Papain-like cysteine endopeptidaseCDDcd02248Peptidase_C1Acoord: 121..335
e-value: 1.57057E-117
score: 336.133
IPR038765Papain-like cysteine peptidase superfamilySUPERFAMILYSSF54001Cysteine proteinasescoord: 29..335