Netrin 1

Overview


Name	Netrin 1
Smed ID	SMED30023593
Length (bp)	1962

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Netrin 1 (SMED30023593) t-SNE clustered cells

Violin plots show distribution of expression levels for Netrin 1 (SMED30023593) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Expression Details

Netrin 1 ( netrin-like ) is expressed during Stage 2, Stage 3 and Stage 4 in the embryonic digestive system and embryonic pharynx

Click to see image symbols and abbreviations


Abbreviation or symbol	Definition
O	oral hemisphere
A	aboral hemisphere
D	dorsal
V	ventral
L	lateral
black arrowhead	embryonic pharynx
red arrowhead	definitive pharynx
black arrows	primitive gut
yellow arrows	primitive ectoderm cells
cyan arrows	brain
cyan arrowheads	nerve cords
blue arrowheads	eye progenitors (trail cells)
purple arrowheads	eyes
scale bar	100 µm

Anatomical Expression

PAGE et. al., 2020

SMED30023593

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
embryonic pharynx	SMED30023593	SMED30023593	smed_20140614	PMID:28072387 Davies et al., 2017
embryonic pharynx	SMED30023593	SMED30023593	smed_20140614	PMID:28072387 Davies et al., 2017
embryonic pharynx	SMED30023593	SMED30023593	smed_20140614	PMID:28072387 Davies et al., 2017
embryonic pharynx	SMED30023593	SMED30023593	smed_20140614	PMID:28072387 Davies et al., 2017
embryonic pharynx	SMED30023593	SMED30023593	smed_20140614	PMID:28072387 Davies et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Netrin 1 vs. Ensembl Human
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029])

HSP 1 Score: 301.982 bits (772), Expect = 2.966e-93
Identity = 185/606 (30.53%), Postives = 299/606 (49.34%), Query Frame = 2

Query:   41 GLVALNGEL---QTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-----SKLRHLVKSNSSCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            GL    G+      C   NG P+ C P  +N A    +  SSTCG   A        ++  +  +SC  CN+ DPK +     + D +     TCW SE   +  +P +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  +  P     T       N  + VC D    M    GG      LI F+   GR        +   Q+W+ AT+IR+++  +    +G+    +   A +  Y +  SD+ +GG+  C+GHA+R +R  DD+  C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GY+R    PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI     +     V+    CD   + SK   +IN K++C K+   +++I   +  G W +F   I  V+   Q   R+ + +       S+W+    + C C   +    YL++ N + +    Q+ ++ ++S ++  W++TW  +  +F  ++K GKC +
Sbjct:   27 GLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCVVS--ERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQ--FPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQ-----NEQEAVCTDSHTDMRPLSGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAF--SRLHTFGDENEDDSELARD-SYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHILKADKAGDWWKFTVNIISVY--KQGTSRIRRGD------QSLWIRSRDIACKCPKIKPLKKYLLLGNAEDSP--DQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603

[Close]

BLAST of Netrin 1 vs. Ensembl Human
Match: NTN3 (netrin 3 [Source:HGNC Symbol;Acc:HGNC:8030])

HSP 1 Score: 252.292 bits (643), Expect = 8.392e-75
Identity = 163/578 (28.20%), Postives = 260/578 (44.98%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTF-KMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPV-YHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNS----SCD-FCQ--RKSKRINFKRFCSKETNFKVNIKSR-ESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSY----LVMANVKTTEFMGQTELILNQSDVIEDWKETW 1759
            C+   G P+ C P L+N A    + ASSTCG     +                  C++ DP+ + S  ++          CW SE +  +  P +V LT+ L K   + F+++  C   P  + + K       W+P  +F+  C L + ++PA          +      +CF    +   G       L+ F+ +     G  L  +   Q+W+ AT++R+  +LT     G     + R+ E  V Y + ++D+ +GG+  C+GHASR +  +     C+C+H T G DC +C   + D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R     +  + AC+ C CH VG+ +G  C+Q +G+C CK GVTG TC  CAPG++Q+ S   PC K         S+      CD  C+  R S RI+ K+FC K+   +V + +R E+RG W RF   +  V+   ++  R           +++WV      CGC     G  Y                    LI  +  ++  W++ W
Sbjct:   30 CHDEGGAPRGCVPGLVNAALGREVLASSTCGRPATRA------------------CDASDPRRAHSPALLTSPGGTASPLCWRSESLPRA--PLNVTLTVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEA-----LCFPAPLAQPDGSG-----LLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRV--VLTRPSTAG-----DPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGA-AGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCKPARGSYRISLKKFCKKDYAVQVAVGARGEARGAWTRFPVAVLAVFRSGEERARRGS--------SALWVPAGDAACGCPRLLPGRRYLLLGGGPGAAAGGAGGRGPGLIAARGSLVLPWRDAW 561

[Close]

BLAST of Netrin 1 vs. Ensembl Human
Match: LAMC1 (laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:6492])

HSP 1 Score: 211.46 bits (537), Expect = 4.038e-57
Identity = 140/435 (32.18%), Postives = 214/435 (49.20%), Query Frame = 2

Query:   65 LQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHES-SYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTF-------------KMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGR--SFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            +  C    G P+ C P  +N A  + + A++TCG    E  C +    +    KSC  C++  P L   +  + D + +   T W S+ +     YP+S+NLTL L K   I+++ ++     P+   IYK   E   W P+QY++  C+ T+             +  AL TD    FSDI+ L             GG+      + F+  +GR  ++    S   Q W+ AT+IR++  L     +G+ +  + +  ++  Y++  SD  +GG+  C+GHAS  ++   D   C C+H+T G DCEKC   FND+PW  AT  + + C  C+CN  S +C FD  ++  +G  HG  C +C DNT G  C++C   +FR     + +  AC  C C  VGSLS T CD   G+C CKPGV G  C  C PG+
Sbjct:   37 MDECTDEGGRPQRCMPEFVNAAFNVTVVATNTCG-TPPEEYCVQT--GVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDE---FSDISPLT------------GGN------VAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVT--LNRLNTFGDEVFNDPKVLKS--YYYAISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTG--HGGHCTNCQDNTDGAHCERCRENFFR-----LGNNEACSSCHCSPVGSLS-TQCDSY-GRCSCKPGVMGDKCDRCQPGF 434

HSP 2 Score: 68.9366 bits (167), Expect = 2.269e-11
Identity = 48/160 (30.00%), Postives = 76/160 (47.50%), Query Frame = 2

Query:  848 PLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEE-FNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSL-SGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            P   G +  ++  + +     C   T GK CE C +  F D    +  +R   +C+ C+C+++      D N      R+ G  C+ C  NT G  CD+C  G+F     P    + CK C C+  G++   + C+ V+G+C C P VTG+ C  C PG+
Sbjct:  774 PCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVR---LCRLCQCSDN-----IDPNAVGNCNRLTGE-CLKCIYNTAGFYCDRCKDGFFGNPLAP-NPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGF 923

HSP 3 Score: 61.6178 bits (148), Expect = 4.638e-9
Identity = 45/141 (31.91%), Postives = 65/141 (46.10%), Query Frame = 2

Query:  908 ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPA-VCKRCECNNHSIKCVFDFNVFLKSGRIHGSSC------IDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHC 1309
            +C ++TAG  C++C + F   P +     NPA  CK C CN             L       SSC       +C  +  G  C  C PG+     Y +     C+ C CH++GS +G  CD  +G+C C+PG+TG+ C  C
Sbjct:  851 KCIYNTAGFYCDRCKDGFFGNPLAP----NPADKCKACNCN-------------LYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGF-----YNLQSGQGCERCDCHALGSTNGQ-CDIRTGQCECQPGITGQHCERC 968

HSP 4 Score: 51.2174 bits (121), Expect = 8.107e-6
Identity = 43/144 (29.86%), Postives = 55/144 (38.19%), Query Frame = 2

Query:  905 CECQHSTAGKDCEKC-----HEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            C C     G+ CE C      E  N  P+S         C  C CN HS  C  +  V             +C DNT GP C++C+ GY+          + C+PC C    S +  P  +      C  G TGK C  C  GY
Sbjct:  690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSP--------CVLCACNGHSETCDPETGV------------CNCRDNTAGPHCEKCSDGYYGDSTAGT--SSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGY 811

HSP 5 Score: 50.8322 bits (120), Expect = 9.133e-6
Identity = 40/142 (28.17%), Postives = 61/142 (42.96%), Query Frame = 2

Query:  896 TYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            T QCEC     G+DC  C   F +       +++   C+RC+C  H++    +    +++G+       +C     G  C++C   +F       +    CKPC CH  GSLS    D   G+C C+ G  G  C  C   Y
Sbjct:  902 TGQCECLPHVTGQDCGACDPGFYN-------LQSGQGCERCDC--HALGST-NGQCDIRTGQC------ECQPGITGQHCERCEVNHFG------FGPEGCKPCDCHPEGSLSLQCKD--DGRCECREGFVGNRCDQCEENY 1019

[Close]

BLAST of Netrin 1 vs. Ensembl Human
Match: LAMC3 (laminin subunit gamma 3 [Source:HGNC Symbol;Acc:HGNC:6494])

HSP 1 Score: 199.519 bits (506), Expect = 3.601e-53
Identity = 135/432 (31.25%), Postives = 204/432 (47.22%), Query Frame = 2

Query:   65 LQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVH-ESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPA----------LTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGR--SFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            +  CY   G P+ C P+  N A     +AS TCG +  E  C         AH  C++C++ DP+   ++  + D H + + T W S  +     YPTSVN+TL L K   I+++ ++     P+   IYK       W P+Q+++  CQ T+  P                 + FSDI+ L             GG+      + F+  +GR  ++    S   Q W+ +TE+ IS  L     +G+ + ++ +  ++  Y++  SD  +GG+  C+GHAS           C CQH+T G DCE+C   F D+PW+  T      C  C C+  S +C FD  +F  +G  HG  C  C D+T GP C++C   ++  H  P   +  C+PC C S GSL    CD  +G C CKP VTG  C  C PG+
Sbjct:   22 MGACYDGAGRPQRCLPVFENAAFGRLAQASHTCG-SPPEDFCPHVGAAGAGAH--CQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLS------------GGN------VAFSTLEGRPSAYNFEESPGLQEWVTSTELLIS--LDRLNTFGDDIFKDPKVLQS--YYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTG--HGGRCHHCRDHTAGPHCERCQENFY--HWDP---RMPCQPCDCQSAGSLH-LQCDD-TGTCACKPTVTGWKCDRCLPGF 419

HSP 2 Score: 72.0182 bits (175), Expect = 2.877e-12
Identity = 48/153 (31.37%), Postives = 68/153 (44.44%), Query Frame = 2

Query:  866 ASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLS-GTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            A   I  S +     C     G+ CE C + F   P       +P  C +C+C+ +      D N       + G  C+ C  NT G  C+ C  G++     P    + C PC CH  GS+S   PCD V+G+C C P VT + C+ C PG+
Sbjct:  762 ACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPL--GLFGHPQPCHQCQCSGN-----VDPNAVGNCDPLSGH-CLRCLHNTTGDHCEHCQEGFYGSALAP-RPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905

HSP 3 Score: 55.8398 bits (133), Expect = 2.458e-7
Identity = 41/138 (29.71%), Postives = 58/138 (42.03%), Query Frame = 2

Query:  911 CQHSTAGKDCEKCHEEFNDQPWSSATIRNPA-VCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            C H+T G  CE C E F    + SA    PA  C  C C+          +  +    + G     C  +     C +C PG+F      +     C+ C CH +GS     C   +G+C C+PGVTG+ C  C  G+
Sbjct:  834 CLHNTTGDHCEHCQEGF----YGSALAPRPADKCMPCSCHPQG-----SVSEQMPCDPVTGQ--CSCLPHVTARDCSRCYPGFFD-----LQPGRGCRSCKCHPLGSQEDQ-CHPKTGQCTCRPGVTGQACDRCQLGF 954

[Close]

BLAST of Netrin 1 vs. Ensembl Human
Match: NTN5 (netrin 5 [Source:HGNC Symbol;Acc:HGNC:25208])

HSP 1 Score: 183.341 bits (464), Expect = 3.293e-50
Identity = 101/330 (30.61%), Postives = 159/330 (48.18%), Query Frame = 2

Query:  854 CHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVK-------SNSSC-DFCQRKSKRIN--FKRFCSKETNFKVNIKSRESRG-QWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCN 1810
            CHGHA+R    +       C+H T G  CE C     D PW  AT R+P  C  C CN H+ +C F+  +F  SG   G  C  C  +T G  C  C PG++R  + PI+ + AC+ C CH +G+  GT C+Q SG+C CK GVTG TC  C PGY+Q+ S + PC++I +    +        S+  C ++C     R++   +R+C ++   +  + + E+ G  W R    +  V+ +  Q  R    +         WV +  + CGC+  + G  YL++ +         T LIL++  +   W+  W     +   +++ G C 
Sbjct:  159 CHGHAARCAARARPPRC-HCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGT-CNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTRVHMSLRRYCQQDHVLRAQVLASEAAGPAWQRLAVRVLAVYKQRAQPVRRGDQD--------AWVPRADLTCGCLRLQPGTDYLLLGSAVGDP--DPTRLILDRHGLALPWRPRWARPLKRLQQEERAGGCR 476

[Close]

BLAST of Netrin 1 vs. Ensembl Celegans
Match: unc-6 (Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34710])

HSP 1 Score: 310.071 bits (793), Expect = 9.285e-97
Identity = 190/598 (31.77%), Postives = 297/598 (49.67%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYI-LTP--KEHYG-----NLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSS-----CDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNRFTRQK 1828
            C+   G P  C P  IN A    + AS TCG N  +  CT      G   + C+ C++ +   S  + ++ D +  G  TCW+S     S  P +V+LTL L K+  ++++++  C   PD + +YK       W+P+Q+++ +C+  F       D   + +  N  + VC      M  GG+   F  +   P   ++F +  S   Q+W+ AT+I++ +  L+P   E YG     N    E  +     Y +   ++ +GG+  C+GHASR I      Y C+C+H+TAG +CE C     D+PW  AT  +   C  C CN H+ +C FD  +F  SG   G  C++C  NT G  C  C PG+ R  + P+ H+ ACK C CH VGSL G  C+Q SG+C CKPGVTG TC  CA GY+Q+ S   PC KI      + S+ S     C  C+   KR+N K+FC ++   ++ + SRE    W ++   +E V+ R  +       N++  E TS+W+    V C C     G  YL++   K      +  L++N   V+ +W++   ++  +F  +DK+G+C   T  +
Sbjct:   37 CHDHTGRPVRCVPEFINAAFGKPVIASDTCGTNRPDKYCTVKEGPDGIIREQCDTCDARNHFQSHPASLLTDLNSIGNMTCWVST---PSLSPQNVSLTLSLGKKFELTYVSMHFCSRLPDSMALYKSADFGKTWTPFQFYSSECRRIFGR-----DPDVSITKSNEQEAVC-TASHIMGPGGNRVAFPFLENRP-SAQNFEN--SPVLQDWVTATDIKVVFSRLSPDQAELYGLSNDVNSYGNETDDEVKQRYFYSMGELAVGGRCKCNGHASRCIFDKMGRYTCDCKHNTAGTECEMCKPFHYDRPWGRATANSANSCVACNCNQHAKRCRFDAELFRLSGNRSGGVCLNCRHNTAGRNCHLCKPGFVRDTSLPMTHRKACKSCGCHPVGSL-GKSCNQSSGQCVCKPGVTGTTCNRCAKGYQQSRSTVTPCIKIPTKADFIGSSHSEEQDQCSKCRIVPKRLNQKKFCKRDHAVQMVVVSREMVDGWAKYKIVVESVFKRGTE-------NMQRGE-TSLWISPQGVICKCPKLRVGRRYLLLG--KNDSDHERDGLMVNPQTVLVEWEDDIMDKVLRFSKKDKLGQCPEITSHR 611

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Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYI-LTP--KEHYG-----NLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSS-----CDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNRFTRQK 1828
            C+   G P  C P  IN A    + AS TCG N  +  CT      G   + C+ C++ +   S  + ++ D +  G  TCW+S     S  P +V+LTL L K+  ++++++  C   PD + +YK       W+P+Q+++ +C+  F       D   + +  N  + VC      M  GG+   F  +   P   ++F +  S   Q+W+ AT+I++ +  L+P   E YG     N    E  +     Y +   ++ +GG+  C+GHASR I      Y C+C+H+TAG +CE C     D+PW  AT  +   C  C CN H+ +C FD  +F  SG   G  C++C  NT G  C  C PG+ R  + P+ H+ ACK C CH VGSL G  C+Q SG+C CKPGVTG TC  CA GY+Q+ S   PC KI      + S+ S     C  C+   KR+N K+FC ++   ++ + SRE    W ++   +E V+ R  +       N++  E TS+W+    V C C     G  YL++   K      +  L++N   V+ +W++   ++  +F  +DK+G+C   T  +
Sbjct:   37 CHDHTGRPVRCVPEFINAAFGKPVIASDTCGTNRPDKYCTVKEGPDGIIREQCDTCDARNHFQSHPASLLTDLNSIGNMTCWVST---PSLSPQNVSLTLSLGKKFELTYVSMHFCSRLPDSMALYKSADFGKTWTPFQFYSSECRRIFGR-----DPDVSITKSNEQEAVC-TASHIMGPGGNRVAFPFLENRP-SAQNFEN--SPVLQDWVTATDIKVVFSRLSPDQAELYGLSNDVNSYGNETDDEVKQRYFYSMGELAVGGRCKCNGHASRCIFDKMGRYTCDCKHNTAGTECEMCKPFHYDRPWGRATANSANSCVACNCNQHAKRCRFDAELFRLSGNRSGGVCLNCRHNTAGRNCHLCKPGFVRDTSLPMTHRKACKSCGCHPVGSL-GKSCNQSSGQCVCKPGVTGTTCNRCAKGYQQSRSTVTPCIKIPTKADFIGSSHSEEQDQCSKCRIVPKRLNQKKFCKRDHAVQMVVVSREMVDGWAKYKIVVESVFKRGTE-------NMQRGE-TSLWISPQGVICKCPKLRVGRRYLLLG--KNDSDHERDGLMVNPQTVLVEWEDDIMDKVLRFSKKDKLGQCPEITSHR 611

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BLAST of Netrin 1 vs. Ensembl Celegans
Match: lam-2 (Laminin-like protein lam-2 [Source:UniProtKB/Swiss-Prot;Acc:Q18823])

HSP 1 Score: 209.92 bits (533), Expect = 4.593e-57
Identity = 141/443 (31.83%), Postives = 216/443 (48.76%), Query Frame = 2

Query:   74 CYS-ANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESS-YPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTF----KMPAL-----TTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTS----DDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQ--TNSLKN 1345
            CY  A   P+ C P  +N A  + ++ ++TCG       C +      ++   CE C+      S  +K + D ++   ET W S+ + E   YPT+ NLTL L K   I+++ ++     P+   IYK      +W PWQ+++  C+ T+    + P L     T      FSDI+ +             GG+      I F+  +GR       ++E  Q W+ A+ IRIS  L     +G+ + ++ +   +  Y++  SD  +GG+  C+GHAS  + +S    ++   C C+H+T G DC +C   +ND+PW S T      C  C C+  S +C FD  +F ++G  HG  CIDC  NT G  C+QC   ++R+       +N C  C C+ +GSLS T CD   GKC CKPGVTG+ C  C  G+    TN  KN
Sbjct:   40 CYDRATRQPQRCVPDFVNAAFNLEVQVTNTCGTKRPTKFCVQSGHTGQRS--VCETCDDRHEGFSHPAKYLTDFNVGNNETWWQSDTMQEGQQYPTTTNLTLVLGKSFDITYVRLKFISPRPESFTIYKKTHTDSEWEPWQFYSGSCRATYGLSDRAPILPGNEATAQCTKEFSDISPIT------------GGN------IAFSTLEGRPSAHAFEESEVLQKWVTASAIRIS--LNRMNTFGDEVFKDPQVLRS--YYYAISDFAVGGRCKCNGHASECVGSSSVDGENRLVCRCEHNTQGADCNECLPFYNDRPWRSGTSVEANECIACNCSQLSNRCYFDQQLFEETG--HGGHCIDCQGNTQGVHCEQCIANHWRRPG-----ENYCVACGCNEIGSLS-TQCDN-EGKCQCKPGVTGRFCDQCLDGFYDFSTNGCKN 449

HSP 2 Score: 69.707 bits (169), Expect = 4.930e-12
Identity = 47/135 (34.81%), Postives = 63/135 (46.67%), Query Frame = 2

Query:  908 ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCA 1312
            +C  +T G +CE C   +    W  A I     C+ C C     +   +    L+  +  G    DC  N +G QCDQCA G+     Y I     C+ C C  +GS  G  CD  +G+C CKPGVTG+ C  CA
Sbjct:  858 KCIFNTHGFNCENCKPGY----WGDALIEPKGNCQSCGCFAAGTRRPNNDYTLLECNQQDGQ--CDCLPNVIGIQCDQCAHGF-----YNITSGLGCQECNCDPLGS-EGNTCDVNTGQCQCKPGVTGQRCDRCA 980

HSP 3 Score: 52.7582 bits (125), Expect = 9.153e-7
Identity = 45/165 (27.27%), Postives = 71/165 (43.03%), Query Frame = 2

Query:  854 CHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVF--DFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLC------HSVGSLSGTPCDQVSGKC-FCKPGVTGKTCTHCAPGY 1321
            CH H++       ++  C C+H+TAG  CE+C   +    +  A       C++C C N    C+   D +V           C +C +   G +CD+C+ GYF            C  C C      +S+G+     CD+++G+C  C     G  C +C PGY
Sbjct:  738 CHNHSNSC---EAESGSCICEHNTAGDTCERCARGY----YGDALQGTEEDCQKCPCPNDG-PCILHADGDVI----------CTECPNGYTGRRCDECSDGYFGNPK----DGTECVECACSGNTDPNSIGN-----CDKITGECKKCIFNTHGFNCENCKPGY 875

HSP 4 Score: 50.0618 bits (118), Expect = 5.907e-6
Identity = 43/145 (29.66%), Postives = 57/145 (39.31%), Query Frame = 2

Query:  905 CECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYF---RQHAYPIYHKNACK---PCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            CEC     G+ CE C   F  +        +   C +C+C+NHS  C                SCI C  NT G  C++CA GY+    Q       K  C    PC+ H+ G +  T C           G TG+ C  C+ GY
Sbjct:  702 CECLPGFVGQFCESCESGFRRETKFGGPFNH---CIKCDCHNHSNSC-----------EAESGSCI-CEHNTAGDTCERCARGYYGDALQGTEEDCQKCPCPNDGPCILHADGDVICTECPN---------GYTGRRCDECSDGY 822

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BLAST of Netrin 1 vs. Ensembl Celegans
Match: lam-3 (LAMinin related. See also lmb; Laminin alpha chain [Source:UniProtKB/TrEMBL;Acc:G5ECE3])

HSP 1 Score: 166.007 bits (419), Expect = 1.849e-42
Identity = 126/466 (27.04%), Postives = 209/466 (44.85%), Query Frame = 2

Query:  110 PLLINLAQPMHIEASSTCGENGAESIC--TEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFA---KDCQLTFKMPALT-------TDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRN-----AENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDT---YQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFD-------FNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLS--------GTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKN-PCRKISKLRHLVKSNSSC 1399
            P + NLA    I A+ TCG+  AE  C   E        +    +C+  D   +   +  ++  I G    W S  +        VN+T+ L++   +++I +++      G  + +   + + + PWQY+A    +C   F +PA T        D V+  S+ + + P    LE              I  +   GR   +  S   Q +  A  +R+  +++P+    +L++  K++     +    Y +  SDI IGGQ +C+GHA      SD     ++CEC+H+T G+ C +C   FN  PW   T  +P VC++C+C NH+  CV+D       +++  +     G  C++C  NT G  C++C  GY+R      Y ++AC+ C C  VGS+S             Q  G C CKPG  G+ C  CAPGY+   + +  PC +   +       +SC
Sbjct:   50 PNIFNLATNSLITATDTCGQYTAEEYCKLVEHVLLRKTTNTQSPQCDICDAN-NVHKRHPIEYAIDGTRRWWQSPSLANGLRFEKVNITIDLRQEYQVAYIILKMGNSPRPGTWVLEKSLDGEYYEPWQYYAMQDAECMRQFGIPATTGVPRFQKEDEVHCTSEYSKITP----LENGE-----------IHTSLVNGRPGAENTSLELQKFTRARFVRLR-LISPRTLNADLMIINKKSDSLDKSVTMRYFYSISDISIGGQCICYGHAESC--PSDPVTGQFKCECRHNTCGESCNRCCPLFNQLPWKPGTNSHPNVCQQCQCFNHAHSCVYDDELDRNKWSITPEGVYEGGGRCLECAHNTEGFNCERCKDGYYRPSGLSHYREDACRTCECDPVGSVSDACVRDDQSAENGQKPGDCICKPGFGGRRCERCAPGYRNHPTCEPCPCNRAGSVNFDTCDGASC 496

HSP 2 Score: 75.485 bits (184), Expect = 1.004e-13
Identity = 58/171 (33.92%), Postives = 77/171 (45.03%), Query Frame = 2

Query:  854 CHGHASRIIRTSDDTYQC-ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCEC----NNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPC 1351
            CHGH+      + DT  C +C+H+T G  CE C   +       A       C +C C    N+ S  CV      +  GR  G  C  C     G  C+ C  GY+     P +    C PC CH  GSL G  C+ +SG+C CKPGVTG+TC+ C   +   N +   C
Sbjct: 1542 CHGHSQTC---NPDTSVCTDCEHNTFGDFCEHCLPGY----IGDAREGGANACTKCACPLVENSFSDSCVA-----VDHGR--GYVCNSCKPGYTGQYCETCVAGYYGD---PQHIGGTCSPCDCHPDGSLHGA-CNPLSGQCECKPGVTGRTCSMCQERHAFINRVCTSC 1694

HSP 3 Score: 73.9442 bits (180), Expect = 3.406e-13
Identity = 52/177 (29.38%), Postives = 77/177 (43.50%), Query Frame = 2

Query:  809 YHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSC------IDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            +H+G++ +       CH   +   + S++  +CEC+ +  G  C++C E   D       + N   C  C+CN+              +G I GS C       +C     G QCDQC P YF       +    C+ C C+  GS+    CDQ +GKC C+  V G  C  CA GY
Sbjct:  928 HHWGNAQLHTCKPCGCHTQGAVNPQCSEENGECECKENYIGAQCDRCKENHGD-------VENG--CPACDCND--------------TGSI-GSDCDQVSGQCNCKQGVFGKQCDQCRPSYFN------FTDAGCQFCHCNIYGSIEDGKCDQTTGKCECRENVEGTMCEKCADGY 1074

HSP 4 Score: 63.929 bits (154), Expect = 3.736e-10
Identity = 43/140 (30.71%), Postives = 63/140 (45.00%), Query Frame = 2

Query:  902 QCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            QC C+    GK C++C   + +           A C+ C CN +    + D      +G+       +C +N  G  C++CA GYF      I   + C+ C C   GS     C+ V+G+C CKPGVTG  C  C P +
Sbjct: 1006 QCNCKQGVFGKQCDQCRPSYFN--------FTDAGCQFCHCNIYG--SIEDGKCDQTTGKC------ECRENVEGTMCEKCADGYFN-----ITSGDGCEDCGCDPTGS-EDVSCNLVTGQCVCKPGVTGLKCDSCLPNF 1123

HSP 5 Score: 59.6918 bits (143), Expect = 7.603e-9
Identity = 50/140 (35.71%), Postives = 71/140 (50.71%), Query Frame = 2

Query:  908 ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECN---NHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPG 1318
            EC H+T G +CE+C + +  +P   +  R  A C+ CEC+   + S  CV D +   ++G+  G  CI C     G +C++CAPGY R H         C+PC C+  GS++   CD  S  C CK  V G  C  C  G
Sbjct:  389 ECAHNTEGFNCERCKDGYY-RPSGLSHYREDA-CRTCECDPVGSVSDACVRD-DQSAENGQKPGD-CI-CKPGFGGRRCERCAPGY-RNHP-------TCEPCPCNRAGSVNFDTCDGAS--CQCKANVEGIYCDRCKAG 513

HSP 6 Score: 55.8398 bits (133), Expect = 1.117e-7
Identity = 49/195 (25.13%), Postives = 74/195 (37.95%), Query Frame = 2

Query:  878 IRTSDDTYQC-ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLS----------------------------------------------GTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            + +++D Y C  C     G  CE C + F + P +         C  C CN + I  +   N   ++G+     C+ C  +T G  C+ C     ++H +     + CKPC CH+ G+++                                              G+ CDQVSG+C CK GV GK C  C P Y
Sbjct:  849 VASNEDNYVCINCPLGYEGNKCEYCSDGFFEDPLTGK-------CIECTCNGN-IDPMGIGNCDSETGK-----CLKCIGHTTGDSCESC-----KEHHWGNAQLHTCKPCGCHTQGAVNPQCSEENGECECKENYIGAQCDRCKENHGDVENGCPACDCNDTGSIGSDCDQVSGQCNCKQGVFGKQCDQCRPSY 1025

[Close]

BLAST of Netrin 1 vs. Ensembl Celegans
Match: lam-1 (LAMinin related. See also lmb [Source:UniProtKB/TrEMBL;Acc:V6CIX7])

HSP 1 Score: 147.517 bits (371), Expect = 1.841e-36
Identity = 122/444 (27.48%), Postives = 194/444 (43.69%), Query Frame = 2

Query:   98 KPCEPLLINL--AQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSL-------DP-KLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKM-----PALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASR------------IIRTSDDTY-QCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQ--------VSGKCFCKPGVTGKTCTHCAPGY 1321
            + C P+  NL   +   ++A+STCG  G +  C      L +  K C  C+S        +P +LS   + VV   +  K   W        +   +V+++  L+     + + +      P  +II +       W  ++YFA DC  +F       P   TD + T S  + + P            G E ++++I  +      + D +S      L  T +R ++  T     G+ LL + R   +  Y++   +I++ G   C+GHASR            ++  +D  + +CEC H+T G +CEKC   +ND PW  A       C++C CN H+++C FD  V+  SG + G  C DC  NT G  C+QC P ++R     I   + C PC C   GS +   C+         V+GKC+CK  V G  C  C  GY
Sbjct:   35 RSCYPITGNLLIGRKSQLKATSTCGSQGRQRFCI--VSHLEEQTK-CFYCDSRTEWKPQREPYRLSHRIENVVTEVMDDKNRNW----YQSENGAQNVSISFDLEAEFHFTHLIMTFKSFRPAAMIIERSADFGKTWQVYRYFAYDCDSSFPGIPEGPPKKHTDVICT-SQYSDVAPS----------TGGEIVYKVISPHIVTENPYADEIS----TLLKITNLRFNF--TKLHTLGDDLL-DYRPEIDEKYYYAIYEIVVRGSCSCYGHASRCIPIDPHVSPNTVMERADIVHGRCECMHNTEGLNCEKCKAFYNDLPWRPAIGDEKNECRQCNCNRHALRCHFDRAVYESSGFVSGGVCDDCMHNTQGKNCEQCKPFFYRDPRRTIDDPHVCLPCECDKAGSQNKGICEGEEDAERGLVAGKCYCKTNVDGNRCDRCKNGY 453

HSP 2 Score: 67.781 bits (164), Expect = 2.335e-11
Identity = 45/138 (32.61%), Postives = 67/138 (48.55%), Query Frame = 2

Query:  908 ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSI--KCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAP 1315
            +C H+T GK+CE+C   F   P    TI +P VC  CEC+      K + +     + G + G     C  N  G +CD+C  GY+      +   + C  C C+ +G+ +   CD+ +G C CK  VTG+ C  C P
Sbjct:  373 DCMHNTQGKNCEQCKPFFYRDPRR--TIDDPHVCLPCECDKAGSQNKGICEGEEDAERGLVAGK--CYCKTNVDGNRCDRCKNGYWNLTETNV---DGCVACTCNLLGTYNNEGCDKYTGMCTCKRLVTGENCDQCLP 503

HSP 3 Score: 60.4622 bits (145), Expect = 4.075e-9
Identity = 33/81 (40.74%), Postives = 46/81 (56.79%), Query Frame = 2

Query: 1082 IHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKP-GVTGKTCTHCAPGY 1321
            + G  C +C  N VG +CDQCA G +       +  + CK C C +VGSL G  CD+ SG+C C+  G+ G+ C  C PG+
Sbjct:  793 VQGGQC-ECKPNVVGRRCDQCAIGTYG------FGPSGCKKCDCDAVGSL-GNDCDKQSGQCVCREKGIYGRQCNQCQPGF 865

HSP 4 Score: 58.151 bits (139), Expect = 2.006e-8
Identity = 53/168 (31.55%), Postives = 74/168 (44.05%), Query Frame = 2

Query:  854 CHGHASRIIRTSDD--TYQC-ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECN---NHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSL---SGTP---CDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            C+G+    +  S D  T +C +C H T G  CE C + +    +  A ++    C+RC CN    +S K   D        R+ G     C DN +G QCDQCA  +F      +     C+ C C S G +    G P   C+   G+C CKPG  G+ C  C   Y
Sbjct:  988 CNGNIDMAMEGSCDAATGECLKCLHHTEGAQCEHCVDGY----YGDAKLK---TCQRCVCNELGTNSTKGACD--------RVSGQ--CPCHDNIIGMQCDQCAENHFN-----LASGAGCEACGCDSNGVVLNHEGVPHLQCNIFDGQCQCKPGRGGRKCDQCEDLY 1133

HSP 5 Score: 55.0694 bits (131), Expect = 1.673e-7
Identity = 46/166 (27.71%), Postives = 71/166 (42.77%), Query Frame = 2

Query:  839 GGQPLCHGHASR-IIRTSDDTYQ---CECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGT-PCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            GG    + HA    +R S +  Q   C C+    G+ C +C +     P           C+RC+CN + I    + +    +G      C+ C  +T G QC+ C  GY     Y       C+ C+C+ +G+ S    CD+VSG+C C   + G  C  CA  +
Sbjct:  928 GGPTSGYQHADTCYLRNSGNNTQDIVCNCKSGYQGERCGECAQNHWGSPREVG-----GTCERCDCNGN-IDMAMEGSCDAATGE-----CLKCLHHTEGAQCEHCVDGY-----YGDAKLKTCQRCVCNELGTNSTKGACDRVSGQCPCHDNIIGMQCDQCAENH 1077

HSP 6 Score: 49.6766 bits (117), Expect = 8.988e-6
Identity = 43/151 (28.48%), Postives = 62/151 (41.06%), Query Frame = 2

Query:  902 QCECQHSTAGKDCEKCHE-EFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPC 1351
            QC C  +  G  C++C E  FN        + + A C+ C C+++ +    +    L+     G     C     G +CDQC   Y+     P    + C  C C+  GS S   C + +G C C+ G  G  C  CA GY       NPC
Sbjct: 1058 QCPCHDNIIGMQCDQCAENHFN--------LASGAGCEACGCDSNGVVLNHEGVPHLQCNIFDGQ--CQCKPGRGGRKCDQCEDLYWGDPTTP----DGCHRCECNPTGSKS-LQCHRNNGTCECQAGSGGALCNECARGYTGQWPYCNPC 1193

[Close]

BLAST of Netrin 1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0073942)

HSP 1 Score: 244.973 bits (624), Expect = 3.881e-71
Identity = 167/576 (28.99%), Postives = 259/576 (44.97%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGH--NPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAEN--------PV-----------------------YHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNS-----LKNPCRKISKLR---------------------------------HLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLE 1582
            CY+   +P+ C P  +N A    + ASSTCG +GA+  C E+ D      +SC  C+  DP  S  ++ + D +     TCW SE V  S    +V LTL L K+  ++++ ++LC H   PD ++IYK       W P+Q+F+  C+  F  PA  +   +     N  +  C D+ +         L   I F+  +GR     L  +   Q+W+ AT+IR+ +    +     LL  E   A +        P+                        H+  SD  +GG+  C+GHAS+    +     CEC H+TAG+DCE+C     D+PW+ AT +    CK C CN H+ +C F+  +F  S  + G  C +C  +T G  C QC  G++R    P+ H+  CK C CH +GS SG  C+  SG+C CK GVTG TC  CA GY+Q+ S     +K P R I+ L                                  +  +    C  C+  +KR+N  +FC ++      +  R++  + +    E++    R   DP V+   ++
Sbjct:   40 CYNKAHEPRACIPDFVNAAYDAPVVASSTCGSSGAQRYC-EYQDH----ERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGSG--DNVTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQSTGRH-----NEHEARCSDVTR--------PLVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGS-SGKICNSTSGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIKQPPRMINMLDTQNTAPEPDEPESSPGSGGDRNGAAGMAAQSQYYRTEGGRECGKCRVSTKRLNLNKFCKRDYAIMAKVIGRDTSSEAVS--REVQ----RRAMDPDVADYEMD 588

[Close]

BLAST of Netrin 1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0346088)

HSP 1 Score: 244.973 bits (624), Expect = 3.881e-71
Identity = 167/576 (28.99%), Postives = 259/576 (44.97%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGH--NPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAEN--------PV-----------------------YHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNS-----LKNPCRKISKLR---------------------------------HLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLE 1582
            CY+   +P+ C P  +N A    + ASSTCG +GA+  C E+ D      +SC  C+  DP  S  ++ + D +     TCW SE V  S    +V LTL L K+  ++++ ++LC H   PD ++IYK       W P+Q+F+  C+  F  PA  +   +     N  +  C D+ +         L   I F+  +GR     L  +   Q+W+ AT+IR+ +    +     LL  E   A +        P+                        H+  SD  +GG+  C+GHAS+    +     CEC H+TAG+DCE+C     D+PW+ AT +    CK C CN H+ +C F+  +F  S  + G  C +C  +T G  C QC  G++R    P+ H+  CK C CH +GS SG  C+  SG+C CK GVTG TC  CA GY+Q+ S     +K P R I+ L                                  +  +    C  C+  +KR+N  +FC ++      +  R++  + +    E++    R   DP V+   ++
Sbjct:   40 CYNKAHEPRACIPDFVNAAYDAPVVASSTCGSSGAQRYC-EYQDH----ERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGSG--DNVTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQSTGRH-----NEHEARCSDVTR--------PLVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGS-SGKICNSTSGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIKQPPRMINMLDTQNTAPEPDEPESSPGSGGDRNGAAGMAAQSQYYRTEGGRECGKCRVSTKRLNLNKFCKRDYAIMAKVIGRDTSSEAVS--REVQ----RRAMDPDVADYEMD 588

[Close]

BLAST of Netrin 1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0308337)

HSP 1 Score: 242.276 bits (617), Expect = 1.465e-70
Identity = 152/463 (32.83%), Postives = 224/463 (48.38%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGH--NPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAEN--------PV-----------------------YHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRK 1357
            CY+   +P+ C P  +N A    + ASSTCG +GA+  C E+ D      +SC  C+  DP  S  ++ + D +     TCW SE V  S    +V LTL L K+  ++++ ++LC H   PD ++IYK       W P+Q+F+  C+  F  PA  +   +     N  +  C D+ +         L   I F+  +GR     L  +   Q+W+ AT+IR+ +    +     LL  E   A +        P+                        H+  SD  +GG+  C+GHAS+    +     CEC H+TAG+DCE+C     D+PW+ AT +    CK C CN H+ +C F+  +F  S  + G  C +C  +T G  C QC  G++R    P+ H+  CK C CH +GS SG  C+  SG+C CK GVTG TC  CA GY+Q+ S   PC K
Sbjct:   40 CYNKAHEPRACIPDFVNAAYDAPVVASSTCGSSGAQRYC-EYQDH----ERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGSG--DNVTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQSTGRH-----NEHEARCSDVTR--------PLVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGS-SGKICNSTSGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIK 481

[Close]

BLAST of Netrin 1 vs. Ensembl Fly
Match: LanB2 (gene:FBgn0267348 transcript:FBtr0345031)

HSP 1 Score: 202.986 bits (515), Expect = 1.205e-54
Identity = 146/439 (33.26%), Postives = 212/439 (48.29%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHES-SYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMP-------------ALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTS----DDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPG-YFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQ 1327
            CY   G P+ C P  IN A  + IE+++TCGE      C +    + + HK+CE C   D   S     + D H     T W SE + E   +P  VNLTL L K   I+++ +      P+   IYK  SE+  W P+Q+++  C+ T+ +P             AL T   + +SDI+ L+    D E              I F+  +GR  G    ++   Q W+ AT+IRI+  L     +G+ L  + +  ++  Y +  SDI +G +  C+GHAS+ + ++    + T  CEC+H+T G DC++C   +ND  W  +T      CK C CN  + KC FD N+F ++G  HG  C+DC +N  GP C++C    Y R   Y       C  C C  VGS S   C+   GKC CKPGVTG  C  C   Y Q
Sbjct:   57 CYDPYGRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFCIQ---TMNQNHKNCEFCKYNDHNPS----FLTDLHDPQSPTWWQSETMFEGIQHPNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAHALCT---SEYSDISPLR----DGE--------------IAFSTLEGRPSGINFERSGELQEWVTATDIRIT--LDRLNTFGDELFGDSQVLKS--YFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRTG--HGGHCLDCRENRDGPNCERCKENFYMRDDGY-------CVNCACDPVGSRS-LQCNS-HGKCQCKPGVTGDKCDRCDNNYYQ 452

HSP 2 Score: 78.9518 bits (193), Expect = 1.003e-14
Identity = 54/154 (35.06%), Postives = 73/154 (47.40%), Query Frame = 2

Query:  878 IRTSDDTYQC-ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNA-CKPCLCHSVGS----LSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            ++ ++DT  C EC     G  CE+C + F   P  +  +     CK C+CN +      D N      R  G  C+ C  NT G  CDQC  G+F     P+   +  C  C C+  G+     S T CDQV+G+C CKP V G+ C  C PGY
Sbjct:  802 LQINEDTVICTECPKGYFGSRCEQCSDGFFGDP--TGLLGEVQTCKSCDCNGN-----VDPNAVGNCNRTTGE-CLKCIHNTAGEHCDQCLSGHF---GDPLALPHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGECQPGY 944

HSP 3 Score: 72.0182 bits (175), Expect = 1.192e-12
Identity = 46/134 (34.33%), Postives = 64/134 (47.76%), Query Frame = 2

Query:  908 ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHC 1309
            +C H+TAG+ C++C       P +    R    C RC C  +      D     +  ++ G     C  N +G  C +C PGYF      I   N C+ CLC  VGS + T CD+ SG+C C+PGV G+ C  C
Sbjct:  870 KCIHNTAGEHCDQCLSGHFGDPLALPHGR----CDRCSC--YEAGTEQDEQSITRCDQVTGQ--CQCKPNVIGRDCGECQPGYFN-----IRSGNGCENCLCDPVGSYNST-CDRYSGQCHCRPGVMGQRCDQC 989

HSP 4 Score: 51.6026 bits (122), Expect = 2.965e-6
Identity = 44/147 (29.93%), Postives = 63/147 (42.86%), Query Frame = 2

Query:  875 IIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLK--SGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHC 1309
            I R    T QC+C+ +  G+DC +C   +         IR+   C+ C C+      V  +N      SG+ H      C    +G +CDQC   ++       +    CKPC C   GS  G  CDQ +G+C C   V G+ C  C
Sbjct:  916 ITRCDQVTGQCQCKPNVIGRDCGECQPGY-------FNIRSGNGCENCLCDP-----VGSYNSTCDRYSGQCH------CRPGVMGQRCDQCENYFYG------FSSEGCKPCECDESGS-KGFQCDQ-NGQCPCNDNVEGRRCDRC 1036

[Close]

BLAST of Netrin 1 vs. Ensembl Fly
Match: LanB2 (gene:FBgn0267348 transcript:FBtr0076382)

HSP 1 Score: 202.986 bits (515), Expect = 1.205e-54
Identity = 146/439 (33.26%), Postives = 212/439 (48.29%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHES-SYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMP-------------ALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTS----DDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPG-YFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQ 1327
            CY   G P+ C P  IN A  + IE+++TCGE      C +    + + HK+CE C   D   S     + D H     T W SE + E   +P  VNLTL L K   I+++ +      P+   IYK  SE+  W P+Q+++  C+ T+ +P             AL T   + +SDI+ L+    D E              I F+  +GR  G    ++   Q W+ AT+IRI+  L     +G+ L  + +  ++  Y +  SDI +G +  C+GHAS+ + ++    + T  CEC+H+T G DC++C   +ND  W  +T      CK C CN  + KC FD N+F ++G  HG  C+DC +N  GP C++C    Y R   Y       C  C C  VGS S   C+   GKC CKPGVTG  C  C   Y Q
Sbjct:   57 CYDPYGRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFCIQ---TMNQNHKNCEFCKYNDHNPS----FLTDLHDPQSPTWWQSETMFEGIQHPNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAHALCT---SEYSDISPLR----DGE--------------IAFSTLEGRPSGINFERSGELQEWVTATDIRIT--LDRLNTFGDELFGDSQVLKS--YFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRTG--HGGHCLDCRENRDGPNCERCKENFYMRDDGY-------CVNCACDPVGSRS-LQCNS-HGKCQCKPGVTGDKCDRCDNNYYQ 452

HSP 2 Score: 78.9518 bits (193), Expect = 1.003e-14
Identity = 54/154 (35.06%), Postives = 73/154 (47.40%), Query Frame = 2

Query:  878 IRTSDDTYQC-ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNA-CKPCLCHSVGS----LSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            ++ ++DT  C EC     G  CE+C + F   P  +  +     CK C+CN +      D N      R  G  C+ C  NT G  CDQC  G+F     P+   +  C  C C+  G+     S T CDQV+G+C CKP V G+ C  C PGY
Sbjct:  802 LQINEDTVICTECPKGYFGSRCEQCSDGFFGDP--TGLLGEVQTCKSCDCNGN-----VDPNAVGNCNRTTGE-CLKCIHNTAGEHCDQCLSGHF---GDPLALPHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGECQPGY 944

HSP 3 Score: 72.0182 bits (175), Expect = 1.192e-12
Identity = 46/134 (34.33%), Postives = 64/134 (47.76%), Query Frame = 2

Query:  908 ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHC 1309
            +C H+TAG+ C++C       P +    R    C RC C  +      D     +  ++ G     C  N +G  C +C PGYF      I   N C+ CLC  VGS + T CD+ SG+C C+PGV G+ C  C
Sbjct:  870 KCIHNTAGEHCDQCLSGHFGDPLALPHGR----CDRCSC--YEAGTEQDEQSITRCDQVTGQ--CQCKPNVIGRDCGECQPGYFN-----IRSGNGCENCLCDPVGSYNST-CDRYSGQCHCRPGVMGQRCDQC 989

HSP 4 Score: 51.6026 bits (122), Expect = 2.965e-6
Identity = 44/147 (29.93%), Postives = 63/147 (42.86%), Query Frame = 2

Query:  875 IIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLK--SGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHC 1309
            I R    T QC+C+ +  G+DC +C   +         IR+   C+ C C+      V  +N      SG+ H      C    +G +CDQC   ++       +    CKPC C   GS  G  CDQ +G+C C   V G+ C  C
Sbjct:  916 ITRCDQVTGQCQCKPNVIGRDCGECQPGY-------FNIRSGNGCENCLCDP-----VGSYNSTCDRYSGQCH------CRPGVMGQRCDQCENYFYG------FSSEGCKPCECDESGS-KGFQCDQ-NGQCPCNDNVEGRRCDRC 1036

[Close]

BLAST of Netrin 1 vs. Ensembl Zebrafish
Match: ntn1a (netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169])

HSP 1 Score: 311.612 bits (797), Expect = 3.405e-97
Identity = 186/593 (31.37%), Postives = 302/593 (50.93%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAES-ICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSS-----CDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            CY  NG P+ C P  +N A    + ASSTCG+  +   + TE  D+    H++C  C++ DPK +     + D +     TCW S+   +  YP +V LTL L K+  +++++++ C   P+ + I+K       W P+QY++  C+  +  P+  T T       N  + +C D    M    GG      LI F+   GR        +   Q+W+ AT+I++++  +    +G+    +   A +  Y +  SD+ +GG+  C+GHASR ++  D    CEC+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GY+R  + PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI        ++S+     C+   + SK   +IN K++C K+   +V+I   +  G+W +F   I  V+ + +   R     L        WV    V C C   + G  YL++ N + +   GQ+ ++ ++  ++  W++TW  +  +F  ++K GKC +
Sbjct:   40 CYDENGHPRRCIPDFVNAAFGKEVRASSTCGKTPSRYCVVTEKGDE---RHRNCHTCDASDPKKNHPPAYLTDLNNPHNLTCWQSDNYLQ--YPQNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKSWVPFQYYSTQCRKMYNKPSKATITKQ-----NEQEAICTDSHTDMHPLSGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTF--SRLHTFGDENEDDSELARD-SYFYAVSDLQVGGRCKCNGHASRCVKDRDGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKPISHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCANGYQQSRSPIAPCIKIPIAPPTTTASSTEEPSDCESYCKASKGKLKINMKKYCKKDYAVQVHILKADKAGEWWKFTVNIISVYKQGESRIRRGDQFL--------WVRAKDVACKCPKIKSGKKYLLLGNDEDSP--GQSGMVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 602

[Close]

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAES-ICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSS-----CDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            CY  NG P+ C P  +N A    + ASSTCG+  +   + TE  D+    H++C  C++ DPK +     + D +     TCW S+   +  YP +V LTL L K+  +++++++ C   P+ + I+K       W P+QY++  C+  +  P+  T T       N  + +C D    M    GG      LI F+   GR        +   Q+W+ AT+I++++  +    +G+    +   A +  Y +  SD+ +GG+  C+GHASR ++  D    CEC+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GY+R  + PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI        ++S+     C+   + SK   +IN K++C K+   +V+I   +  G+W +F   I  V+ + +   R     L        WV    V C C   + G  YL++ N + +   GQ+ ++ ++  ++  W++TW  +  +F  ++K GKC +
Sbjct:   40 CYDENGHPRRCIPDFVNAAFGKEVRASSTCGKTPSRYCVVTEKGDE---RHRNCHTCDASDPKKNHPPAYLTDLNNPHNLTCWQSDNYLQ--YPQNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKSWVPFQYYSTQCRKMYNKPSKATITKQ-----NEQEAICTDSHTDMHPLSGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTF--SRLHTFGDENEDDSELARD-SYFYAVSDLQVGGRCKCNGHASRCVKDRDGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKPISHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCANGYQQSRSPIAPCIKIPIAPPTTTASSTEEPSDCESYCKASKGKLKINMKKYCKKDYAVQVHILKADKAGEWWKFTVNIISVYKQGESRIRRGDQFL--------WVRAKDVACKCPKIKSGKKYLLLGNDEDSP--GQSGMVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 602

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BLAST of Netrin 1 vs. Ensembl Zebrafish
Match: ntn2 (netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2])

HSP 1 Score: 296.59 bits (758), Expect = 1.731e-91
Identity = 177/599 (29.55%), Postives = 298/599 (49.75%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLL--REKRNAEN-----PVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLR-----HLVKSNSSCD-FCQ--RKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            CY   G  + C P  IN A    +  SS CG   + S C+        A ++C+ C++ DP+ +  +  + D +     TCW SE +  S  P +V LTL L K+  I++++++ C   P+ + IYK       W+P+Q+++  C+  +  P     T       N  + +C D    +    GG      LI F+   GR  G     +   Q+W+  T+IR+  + +  +H   L +  RE  +A       P Y++   D  +GG+  C+GHASR +R  D    CEC+H+T G +C++C     D+PW  AT +    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R     I H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI  ++        +  + CD +C+  + + +IN K++C K+   +V++   E+ G W +F   +  V+ +++ DP     ++       +WVH   + C C     G  +L++ + + T    +  L  +++ ++  W++ W  +  +F  ++K GKC++
Sbjct:   26 CYEETGAARRCIPEFINAAFGQEVSVSSVCGRPVSRS-CSLVERDDRPAVRTCQICDASDPRNAHPASYLTDLNSAHNLTCWQSENLQSS--PLNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGRTWTPYQFYSSQCRRMYNRPNKAAITKQ-----NEQEALCTDGHTDLYPLSGG------LIAFSTLDGRPSGKDFDSSPVLQDWVTVTDIRV--VFSRPQHTRALPMSGRESEDALGAPGSLPTYYYAVGDFQVGGRCKCNGHASRCVREKDGKLLCECKHNTEGPECDRCKPFHYDRPWQRATGKEANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGKAITHRRACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVIKPTAVISTTEEPADCDSYCKPLKGNLKINMKKYCKKDYAVQVSVLDMETVGDWAKFSVSLMSVY-KSRGDPLKRGDHM-------LWVHMKDLACKCPRIHMGKRFLILGSTEGTANPERPGLQADKNSLVIQWRDIWTRRLRKFQRKEKKGKCSK 599

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BLAST of Netrin 1 vs. Ensembl Zebrafish
Match: ntn2 (netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2])

HSP 1 Score: 296.975 bits (759), Expect = 1.761e-91
Identity = 177/599 (29.55%), Postives = 298/599 (49.75%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLL--REKRNAEN-----PVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLR-----HLVKSNSSCD-FCQ--RKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            CY   G  + C P  IN A    +  SS CG   + S C+        A ++C+ C++ DP+ +  +  + D +     TCW SE +  S  P +V LTL L K+  I++++++ C   P+ + IYK       W+P+Q+++  C+  +  P     T       N  + +C D    +    GG      LI F+   GR  G     +   Q+W+  T+IR+  + +  +H   L +  RE  +A       P Y++   D  +GG+  C+GHASR +R  D    CEC+H+T G +C++C     D+PW  AT +    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R     I H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI  ++        +  + CD +C+  + + +IN K++C K+   +V++   E+ G W +F   +  V+ +++ DP     ++       +WVH   + C C     G  +L++ + + T    +  L  +++ ++  W++ W  +  +F  ++K GKC++
Sbjct:   35 CYEETGAARRCIPEFINAAFGQEVSVSSVCGRPVSRS-CSLVERDDRPAVRTCQICDASDPRNAHPASYLTDLNSAHNLTCWQSENLQSS--PLNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGRTWTPYQFYSSQCRRMYNRPNKAAITKQ-----NEQEALCTDGHTDLYPLSGG------LIAFSTLDGRPSGKDFDSSPVLQDWVTVTDIRV--VFSRPQHTRALPMSGRESEDALGAPGSLPTYYYAVGDFQVGGRCKCNGHASRCVREKDGKLLCECKHNTEGPECDRCKPFHYDRPWQRATGKEANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGKAITHRRACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVIKPTAVISTTEEPADCDSYCKPLKGNLKINMKKYCKKDYAVQVSVLDMETVGDWAKFSVSLMSVY-KSRGDPLKRGDHM-------LWVHMKDLACKCPRIHMGKRFLILGSTEGTANPERPGLQADKNSLVIQWRDIWTRRLRKFQRKEKKGKCSK 608

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BLAST of Netrin 1 vs. Ensembl Zebrafish
Match: ntn1b (netrin 1b [Source:ZFIN;Acc:ZDB-GENE-990415-168])

HSP 1 Score: 291.967 bits (746), Expect = 8.704e-90
Identity = 180/602 (29.90%), Postives = 295/602 (49.00%), Query Frame = 2

Query:   44 LVALNGELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAES-ICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNS-----SCD-FCQ--RKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTR-NQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
              A +     CY  NG+P+ C P  +N A    +  SSTCG   +   + TE   K  +  + C  C++ DPK +     + D +     TCW SE   +  YP +V LTL L K+  +++++++ C   P+ + I+K       W P+Q+++  C+  +  P+    T       N  + +C D    M    GG      LI F+   GR        +   Q+W+ AT+I++++       +G+    +   A +  Y +  SD+ +GG+  C+GHAS+ ++  +    CEC+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GY+R  +  I H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI         +S      CD  C+  +   ++  K++C K+   +V++   +  G+W +F   I  V+ +   +  R  QL         +WV    V C C   + G  YL+M + +  +  GQ+ ++ ++  ++  WK+ W  +  +F  +DK GKC
Sbjct:   30 FAAQSSPPDPCYDENGNPRRCIPDFVNSAFGKDVRVSSTCGSPPSRYCVVTE---KGEERSRDCNICDATDPKKTHPPAYLTDLNNPHNLTCWQSENYVQ--YPQNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKTWVPFQFYSTQCKKMYNKPSKAAITKQ-----NEQEAICTDSHTDMQPLTGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFNRL--HTFGDENEDDSELARD-SYFYAVSDLQVGGRCKCNGHASKCVKDREGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKAISHRRACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAAPTSSYSSPDGPTDCDSHCKAPKGKMKVTMKKYCKKDFAVQVHVLKGDKAGEWWKFTINIISVYKQGGHRIRRGDQL---------LWVRAKDVACKCPKIKPGRKYLLMGSDEEEDSRGQSGVVADRGSLLIPWKDLWARRLRKFQQRDKRGKC 602

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BLAST of Netrin 1 vs. Ensembl Xenopus
Match: ntn1 (netrin 1 [Source:NCBI gene;Acc:779839])

HSP 1 Score: 290.041 bits (741), Expect = 8.215e-89
Identity = 181/595 (30.42%), Postives = 289/595 (48.57%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISE-GVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFR-LIPFNPRQGRSFGDVL--SKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKS----------NSSCD-FCQRKSKRI--NFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
            CY A   PK C P  IN+A    +  S+TCG    + +C  + D      + C+ C+   P+ S     + D+     +TCW SE G+   ++P +V LTL L +R  + + ++  C   PD + IYK       W P+Q+++  C+  +        T +  S     +  C D +      G + L + L+ F P  GR        S   Q+W+ AT+IR+ +    + H+G  +   ++ A      +G S+I +GG+  C+GHASR      +   CECQH+T G +C+ C   + D+PW  AT  N   C  CECN HS +C F+  ++  SGR  G  C++C  NT G  C  C  GY R  + PI  + ACKPC CH +G+++   C+Q +G+C CK GVTG TC  CAPGY+Q+ S   PC +I +      S           + C  +C+    R+  N +++C K+   +  + S E  G+W +F + +  V+ + +   R     L        WV    + C C+  + G SYL++ N +  E      LIL+++ +   W++ W  +  +F  Q++ GKC
Sbjct:   42 CYDAKQRPKYCIPDFINVALGQEVITSNTCGRT-PQKLCY-FLDSTNVTSRRCQLCDQKRPENSYPPSYMTDTDA---QTCWKSESGI---TFPQNVTLTLPLGRRFELVYASLRFCSPRPDSMAIYKSMDYGKTWIPFQFYSTHCRRVYDQ-----ATTSAISKPMQHEATCTDFQT-----GVKPLTKGLVAFMPLAGRPSARRFEYSPVLQDWVTATDIRVVFN---RLHHGKKMGIRRKTA-----FYGVSEIQVGGRCKCNGHASRCT-AGKEGLMCECQHNTIGPECDACKPFYYDRPWQRATPSNAHECVACECNLHSHRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKQGYKRDLSKPITSRKACKPCQCHPIGAVNAM-CNQTTGQCQCKTGVTGPTCNRCAPGYQQSRSAHMPCVRIQEEMTTTASYPQEWKAGTNGTECQSYCKPSHSRVHMNLRKYCKKDYVLRAQLLSMEKSGEWWQFTATVLTVYRQRRVPIRRGDQPL--------WVPDHDLACDCLRVQVGKSYLIIGNDE--ESPDPARLILDKNSLALPWRDVWGHKLRRFQQQERRGKC 598

[Close]

BLAST of Netrin 1 vs. Ensembl Xenopus
Match: rps16 (ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-5786511])

HSP 1 Score: 277.33 bits (708), Expect = 3.177e-84
Identity = 177/593 (29.85%), Postives = 291/593 (49.07%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNA--ENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKL---RHLVKSNSSCD---FCQ--RKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVK-TTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
            CY  +G P+ C P  +N A    ++ASSTCG             +L   H     C++ DP+ S  +  + D +  G  TCW SE     S   +V+LTL L K+  +++++++ C   P+ + I+K       W P+QY++  C+  +  P+  + T       N  + +C D +  +    GG      LI F+   GR     L  +   Q+WL AT+IR+ +   P     +LL  ++  A  E P +++   +  +GG+  C+GHASR  +  +    C+C+H+T G +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R  +  I  + ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI  +     L  +    D   +C+  + + +IN K++C K+   +VN+   E  G W +F   I  V+    +D R+ + +        +W+H   + C C        YLVM + +  +E  G   L  +++ ++  W++ W  +  +   ++K GKC
Sbjct:   41 CYDEHGLPRRCVPEFVNAAFNKEVQASSTCG-------------RLATRH-----CDTTDPRKSYPASYLTDLNTAGNMTCWRSETFPRHS-SQNVSLTLSLGKKFEVTYVSLQFCSPRPESVAIFKSMDYGKSWVPYQYYSSQCRKVYGKPSRASVTKQ-----NEQEALCTDGQTELYPLTGG------LIAFSTLDGRPSAQDLDNSPVLQDWLTATDIRV-FFSRP-----HLLGNKESEASDEGPGFYYSVGEFQVGGRCKCNGHASRCGKDKEARLICDCKHNTEGPECDRCKPFHYDRPWQRATAREANECMACTCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDVSRAITDRRACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGLTCNRCAKGYQQSRSPIAPCIKIPAVVPTPALTSTEEPADCEQYCKPPKGNYKINLKKYCKKDFVVQVNVLEMEMVGSWAKFTVNILSVY--KCRDDRIKRGD------NFLWIHIKDLSCKCPKILLSRRYLVMGSSEGPSERPG---LTADKNSMVIQWRDAWTRRLRKLQRREKKGKC 585

[Close]

BLAST of Netrin 1 vs. Ensembl Xenopus
Match: rps16 (ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-5786511])

HSP 1 Score: 262.307 bits (669), Expect = 1.029e-78
Identity = 170/587 (28.96%), Postives = 277/587 (47.19%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNA--ENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTE---LILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
            CY  +G P+ C P  +N A    ++ASSTCG             +L   H     C++ DP+ S  +  + D +  G  TCW SE     S   +V+LTL L K+  +++++++ C   P+ + I+K       W P+QY++  C+  +  P+  + T       N  + +C D +  +    GG      LI F+   GR     L  +   Q+WL AT+IR+ +   P     +LL  ++  A  E P +++   +  +GG+  C+GHASR  +  +    C+C+H+T G +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R  +  I  + ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI  +       S+                  +    +VN+   E  G W +F   I  V+    +D R+ + +        +W+H   + C C        YLVM + +     G +E   L  +++ ++  W++ W  +  +   ++K GKC
Sbjct:   41 CYDEHGLPRRCVPEFVNAAFNKEVQASSTCG-------------RLATRH-----CDTTDPRKSYPASYLTDLNTAGNMTCWRSETFPRHS-SQNVSLTLSLGKKFEVTYVSLQFCSPRPESVAIFKSMDYGKSWVPYQYYSSQCRKVYGKPSRASVTKQ-----NEQEALCTDGQTELYPLTGG------LIAFSTLDGRPSAQDLDNSPVLQDWLTATDIRV-FFSRP-----HLLGNKESEASDEGPGFYYSVGEFQVGGRCKCNGHASRCGKDKEARLICDCKHNTEGPECDRCKPFHYDRPWQRATAREANECMACTCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDVSRAITDRRACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGLTCNRCAKGYQQSRSPIAPCIKIPAVVPTPALTST-----------------EEPAVVQVNVLEMEMVGSWAKFTVNILSVY--KCRDDRIKRGD------NFLWIHIKDLSCKCPKILLSRRYLVMGSSE-----GPSERPGLTADKNSMVIQWRDAWTRRLRKLQRREKKGKC 560

[Close]

BLAST of Netrin 1 vs. Ensembl Xenopus
Match: utp4 (UTP4 small subunit processome component [Source:Xenbase;Acc:XB-GENE-977755])

HSP 1 Score: 208.764 bits (530), Expect = 2.521e-56
Identity = 140/442 (31.67%), Postives = 217/442 (49.10%), Query Frame = 2

Query:   44 LVALNGELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHES-SYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFK-------------MPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGR--SFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            L  +   +  CY   G P+ C P  +N A    + A++TCG    E  C +    +    KSC  C+S    L   ++ + D + + + T W S+ +     YP+++NLTL L K   I+++ ++     P+   +YK   E   W P+QY++  C+ T++               AL TD    FSDI+ L             GG+      + F+  +GR  ++    S   Q W+ AT+IR++  L     +G+ +  + +  ++  Y++  SD  +GG+  C+GHAS  +R   +   C C+H+T G DCEKC   +ND+PW  +T  +P  C  C CN  S +C FD  ++  +G  HG  C  C DNT GP C++C   Y+RQ      +   C  C C+ VGSLS T CD   G+C CKPGV G+ C  C PG+
Sbjct:    9 LGTVRAAMDECYE-EGSPQRCMPEFVNAAFNATVVATNTCG-TPPEEYCVQT--GVTGVTKSCHICDSGQFHLQHGAEYLTDYNNQAEITWWQSQTMLAGIQYPSTINLTLHLGKAFDITYVRLKFHTSRPESFALYKRTHEDGPWIPYQYYSGSCEKTYQKFNRGFIRTGEDEQQALCTDE---FSDISPLT------------GGN------VAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVT--LNRLNTFGDEVFSDPKVLKS--YYYAISDFAVGGRCKCNGHASECVRNEFEKIVCNCKHNTFGSDCEKCLPFYNDRPWRRSTADSPNECLPCNCNGRSQECYFDPELYRSTG--HGGHCTGCADNTDGPNCERCRENYYRQD-----NNEPCHACQCNPVGSLS-TQCDNY-GRCSCKPGVMGEKCDRCQPGF 412

HSP 2 Score: 70.0922 bits (170), Expect = 1.061e-11
Identity = 48/161 (29.81%), Postives = 75/161 (46.58%), Query Frame = 2

Query:  848 PLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKN--ACKPCLCHSVGSLSG-TPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            P   G +  ++  + +     C   T GK CE C + +   P        P  C+ CEC+N+      D N      R+ G  C+ C  NT G  CD+C  G++     P+       C+ C C+  G++ G + C+QV+G+C C P VT + C+ C PG+
Sbjct:  752 PCPGGSSCAVVPRTKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRP--CRICECSNN-----IDPNAVGNCDRLTGE-CLKCIYNTGGFYCDRCRDGFY---GNPLAQNPDLKCRACSCNPYGTVKGQSGCNQVTGQCECLPHVTERDCSACEPGF 901

HSP 3 Score: 64.3142 bits (155), Expect = 6.193e-10
Identity = 42/139 (30.22%), Postives = 67/139 (48.20%), Query Frame = 2

Query:  908 ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAV-CKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            +C ++T G  C++C + F   P +    +NP + C+ C CN +         V  +SG    +   +C  +     C  C PG+     Y +     C+ C CHS+GS SG  CD  +G+C C PG++G+ C  C P +
Sbjct:  829 KCIYNTGGFYCDRCRDGFYGNPLA----QNPDLKCRACSCNPYGT-------VKGQSGCNQVTGQCECLPHVTERDCSACEPGF-----YNLLSGRGCERCDCHSLGSTSGQ-CDVRTGQCECHPGISGQQCQQCEPNH 950

HSP 4 Score: 52.373 bits (124), Expect = 3.049e-6
Identity = 44/154 (28.57%), Postives = 58/154 (37.66%), Query Frame = 2

Query:  905 CECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY----KQTNSLKNPCR 1354
            C C     G+ CE+C   +  +  S       + C  C CN HS  C  +  V             DC  NT GP C++C+ GY+          + C+PC C    S +  P  +      C  G TGK C  C  GY       N    PCR
Sbjct:  668 CSCPTGYIGQFCERCAPGYRRENPSQGPY---SPCVLCTCNGHSDTCDPESGV------------CDCQHNTAGPHCERCSEGYYGDST--TGSASDCQPCPCPGGSSCAVVPRTKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRPCR 804

[Close]

BLAST of Netrin 1 vs. Ensembl Xenopus
Match: utp4 (UTP4 small subunit processome component [Source:Xenbase;Acc:XB-GENE-977755])

HSP 1 Score: 208.764 bits (530), Expect = 2.767e-56
Identity = 140/442 (31.67%), Postives = 217/442 (49.10%), Query Frame = 2

Query:   44 LVALNGELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHES-SYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFK-------------MPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGR--SFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            L  +   +  CY   G P+ C P  +N A    + A++TCG    E  C +    +    KSC  C+S    L   ++ + D + + + T W S+ +     YP+++NLTL L K   I+++ ++     P+   +YK   E   W P+QY++  C+ T++               AL TD    FSDI+ L             GG+      + F+  +GR  ++    S   Q W+ AT+IR++  L     +G+ +  + +  ++  Y++  SD  +GG+  C+GHAS  +R   +   C C+H+T G DCEKC   +ND+PW  +T  +P  C  C CN  S +C FD  ++  +G  HG  C  C DNT GP C++C   Y+RQ      +   C  C C+ VGSLS T CD   G+C CKPGV G+ C  C PG+
Sbjct:   12 LGTVRAAMDECYE-EGSPQRCMPEFVNAAFNATVVATNTCG-TPPEEYCVQT--GVTGVTKSCHICDSGQFHLQHGAEYLTDYNNQAEITWWQSQTMLAGIQYPSTINLTLHLGKAFDITYVRLKFHTSRPESFALYKRTHEDGPWIPYQYYSGSCEKTYQKFNRGFIRTGEDEQQALCTDE---FSDISPLT------------GGN------VAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVT--LNRLNTFGDEVFSDPKVLKS--YYYAISDFAVGGRCKCNGHASECVRNEFEKIVCNCKHNTFGSDCEKCLPFYNDRPWRRSTADSPNECLPCNCNGRSQECYFDPELYRSTG--HGGHCTGCADNTDGPNCERCRENYYRQD-----NNEPCHACQCNPVGSLS-TQCDNY-GRCSCKPGVMGEKCDRCQPGF 415

HSP 2 Score: 70.0922 bits (170), Expect = 1.098e-11
Identity = 48/161 (29.81%), Postives = 75/161 (46.58%), Query Frame = 2

Query:  848 PLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKN--ACKPCLCHSVGSLSG-TPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            P   G +  ++  + +     C   T GK CE C + +   P        P  C+ CEC+N+      D N      R+ G  C+ C  NT G  CD+C  G++     P+       C+ C C+  G++ G + C+QV+G+C C P VT + C+ C PG+
Sbjct:  755 PCPGGSSCAVVPRTKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRP--CRICECSNN-----IDPNAVGNCDRLTGE-CLKCIYNTGGFYCDRCRDGFY---GNPLAQNPDLKCRACSCNPYGTVKGQSGCNQVTGQCECLPHVTERDCSACEPGF 904

HSP 3 Score: 64.3142 bits (155), Expect = 6.194e-10
Identity = 42/139 (30.22%), Postives = 67/139 (48.20%), Query Frame = 2

Query:  908 ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAV-CKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            +C ++T G  C++C + F   P +    +NP + C+ C CN +         V  +SG    +   +C  +     C  C PG+     Y +     C+ C CHS+GS SG  CD  +G+C C PG++G+ C  C P +
Sbjct:  832 KCIYNTGGFYCDRCRDGFYGNPLA----QNPDLKCRACSCNPYGT-------VKGQSGCNQVTGQCECLPHVTERDCSACEPGF-----YNLLSGRGCERCDCHSLGSTSGQ-CDVRTGQCECHPGISGQQCQQCEPNH 953

HSP 4 Score: 51.9878 bits (123), Expect = 3.349e-6
Identity = 44/154 (28.57%), Postives = 58/154 (37.66%), Query Frame = 2

Query:  905 CECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY----KQTNSLKNPCR 1354
            C C     G+ CE+C   +  +  S       + C  C CN HS  C  +  V             DC  NT GP C++C+ GY+          + C+PC C    S +  P  +      C  G TGK C  C  GY       N    PCR
Sbjct:  671 CSCPTGYIGQFCERCAPGYRRENPSQGPY---SPCVLCTCNGHSDTCDPESGV------------CDCQHNTAGPHCERCSEGYYGDST--TGSASDCQPCPCPGGSSCAVVPRTKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRPCR 807

[Close]

BLAST of Netrin 1 vs. Ensembl Mouse
Match: Ntn1 (netrin 1 [Source:MGI Symbol;Acc:MGI:105088])

HSP 1 Score: 301.212 bits (770), Expect = 3.380e-93
Identity = 184/606 (30.36%), Postives = 300/606 (49.50%), Query Frame = 2

Query:   41 GLVALNGEL---QTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-----SKLRHLVKSNSSCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            GL    G+      C   NG P+ C P  +N A    +  SSTCG   A        ++  +  +SC  CNS DPK +     + D +     TCW SE   +  +P +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  +  P     T       N  + VC D    M    GG      LI F+   GR        +   Q+W+ AT+IR+++  +    +G+    +   A +  Y++  SD+ +GG+  C+GHA+R +R  DD+  C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R    PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI     +     V+    CD   + SK   ++N K++C K+   +++I   +  G W +F   I  V+   Q   R+ + +       S+W+    + C C   +    YL++ N + +    Q+ ++ ++S ++  W++TW  +  +F  ++K GKC +
Sbjct:   27 GLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCVVS--ERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQ--FPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQ-----NEQEAVCTDSHTDMRPLSGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAF--SRLHTFGDENEDDSELARD-SYYYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKMNMKKYCRKDYAVQIHILKADKAGDWWKFTVNIISVY--KQGTSRIRRGD------QSLWIRSRDIACKCPKIKPLKKYLLLGNAEDSP--DQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603

[Close]

Query:   41 GLVALNGEL---QTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-----SKLRHLVKSNSSCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            GL    G+      C   NG P+ C P  +N A    +  SSTCG   A        ++  +  +SC  CNS DPK +     + D +     TCW SE   +  +P +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  +  P     T       N  + VC D    M    GG      LI F+   GR        +   Q+W+ AT+IR+++  +    +G+    +   A +  Y++  SD+ +GG+  C+GHA+R +R  DD+  C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R    PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI     +     V+    CD   + SK   ++N K++C K+   +++I   +  G W +F   I  V+   Q   R+ + +       S+W+    + C C   +    YL++ N + +    Q+ ++ ++S ++  W++TW  +  +F  ++K GKC +
Sbjct:   27 GLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCVVS--ERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQ--FPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQ-----NEQEAVCTDSHTDMRPLSGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAF--SRLHTFGDENEDDSELARD-SYYYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKMNMKKYCRKDYAVQIHILKADKAGDWWKFTVNIISVY--KQGTSRIRRGD------QSLWIRSRDIACKCPKIKPLKKYLLLGNAEDSP--DQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603

[Close]

BLAST of Netrin 1 vs. Ensembl Mouse
Match: Ntn3 (netrin 3 [Source:MGI Symbol;Acc:MGI:1341188])

HSP 1 Score: 253.832 bits (647), Expect = 1.554e-75
Identity = 162/585 (27.69%), Postives = 265/585 (45.30%), Query Frame = 2

Query:   50 ALNGELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTF-KMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-----SKLRHLVKSNSSCDFCQ--RKSKRINFKRFCSKETNFKVNIKSR-ESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTE----LILNQSDVIEDWKETW 1759
             L      CY    +P+ C P L+N A    + ASSTCG +                      C+S DP+ + S+ ++  +       CW S+ + ++  P +V LT+ L K   + F+++  C   P  + + K       W P  +F+  C L + ++PA          +      +CF   ++   GG      L+ F+ + G   G  L  +   Q+W+ AT+IRI  +LT     G+     +       Y + ++++ +GG+  C+GHASR +  +     C+CQH T G DC +C   + D+PW  AT +    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R     +  + AC+ C CH VG+ +G  C+Q +G+C CK GVTG TC  CAPG++Q+ S   PC K      ++    V+       C+  R S RI+ K+FC K+   +V + +R E+RG W RF   +  V+   ++  R           +++WV      CGC     G  YL++                 L   +  ++  W++ W
Sbjct:   22 GLPASADPCYDEAREPRSCIPGLVNAALGREVLASSTCGRSANRV------------------CDSSDPQRAHSADLLTSAPGTASPLCWRSDLLQQA--PFNVTLTVPLGKAFELVFVSLRFCSAPPTSVALLKSQDHGRSWVPLGFFSSSCTLDYGRLPAPADGPSGPGPEA-----LCFPAPQAQPDGGG-----LLAFSVQDGSPQGLDLDNSPVLQDWVTATDIRI--VLTRPAIQGD----TRDGGVTVPYSYSATELQVGGRCKCNGHASRCLLDTHGHLVCDCQHGTEGPDCSRCKPFYCDRPWQRATGQEAHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRVLSDRRACRACDCHPVGA-AGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPVPGPTEESSPVEPQDCESHCRPARGSYRISLKKFCRKDYAVQVAVGARGEARGSWTRFPVAVLAVFRSGEERARRGS--------SALWVPTLDAACGCPRLLPGRRYLLLGGGPGAAAGSTAGRGQGLSAARGSLVLPWRDAW 561

[Close]

BLAST of Netrin 1 vs. Ensembl Mouse
Match: Lamc1 (laminin, gamma 1 [Source:MGI Symbol;Acc:MGI:99914])

HSP 1 Score: 211.846 bits (538), Expect = 1.725e-57
Identity = 140/439 (31.89%), Postives = 215/439 (48.97%), Query Frame = 2

Query:   53 LNGELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHES-SYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTF-------------KMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGR--SFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            +   +  C    G P+ C P  +N A  + + A++TCG    E  C +    +    KSC  C++    L   +  + D + +   T W S+ +     YP S+NLTL L K   I+++ ++     P+   IYK   E   W P+QY++  C+ T+             +  AL TD    FSDI+ L             GG+      + F+  +GR  ++    S   Q W+ AT+IR++  L     +G+ +  + +  ++  Y++  SD  +GG+  C+GHAS  ++   D   C C+H+T G DCEKC   FND+PW  AT  + + C  C+CN  S +C FD  ++  +G  HG  C +C DNT G +C++C   +FR     + +  AC PC C  VGSLS T CD   G+C CKPGV G  C  C PG+
Sbjct:   31 VRAAMDECADEGGRPQRCMPEFVNAAFNVTVVATNTCG-TPPEEYCVQT--GVTGVTKSCHLCDAGQQHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDE---FSDISPLT------------GGN------VAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVT--LNRLNTFGDEVFNDPKVLKS--YYYAISDFAVGGRCKCNGHASECVKNEFDKLMCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTG--HGGHCTNCRDNTDGAKCERCRENFFR-----LGNTEACSPCHCSPVGSLS-TQCDSY-GRCSCKPGVMGDKCDRCQPGF 432

HSP 2 Score: 76.2554 bits (186), Expect = 9.918e-14
Identity = 52/160 (32.50%), Postives = 78/160 (48.75%), Query Frame = 2

Query:  848 PLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEE-FNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSG-TPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            P   G +  I+  + +     C   TAGK CE C +  F D   S+  +R   +C+ C+CN++      D N      R+ G  C+ C  NT G  CD+C  G+F     P    + CK C C+  G++   + C+ V+G+C C P V+G+ C  C PGY
Sbjct:  772 PCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGYFGDPLGSNGPVR---LCRPCQCNDN-----IDPNAVGNCNRLTGE-CLKCIYNTAGFYCDRCKEGFFGNPLAP-NPADKCKACACNPYGTVQQQSSCNPVTGQCQCLPHVSGRDCGTCDPGY 921

HSP 3 Score: 62.7734 bits (151), Expect = 1.428e-9
Identity = 45/135 (33.33%), Postives = 65/135 (48.15%), Query Frame = 2

Query:  908 ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPA-VCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHC 1309
            +C ++TAG  C++C E F   P +     NPA  CK C CN +         V  +S     +    C  +  G  C  C PGY     Y +     C+ C CH++GS +G  CD  +G+C C+PG+TG+ C  C
Sbjct:  849 KCIYNTAGFYCDRCKEGFFGNPLAP----NPADKCKACACNPYGT-------VQQQSSCNPVTGQCQCLPHVSGRDCGTCDPGY-----YNLQSGQGCERCDCHALGSTNGQ-CDIRTGQCECQPGITGQHCERC 966

HSP 4 Score: 51.6026 bits (122), Expect = 3.666e-6
Identity = 39/139 (28.06%), Postives = 56/139 (40.29%), Query Frame = 2

Query:  905 CECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            C C     G+ CE C   +  +   + ++   + C  C CN HS  C  +  V             DC DNT GP C++C+ GY+      +   + C+PC C    S +  P  +      C  G  GK C  C  GY
Sbjct:  688 CTCPVGYGGQFCETCLPGYRRE---TPSLGPYSPCVLCTCNGHSETCDPETGV------------CDCRDNTAGPHCEKCSDGYYGDST--LGTSSDCQPCPCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGY 809

[Close]

BLAST of Netrin 1 vs. Ensembl Mouse
Match: Lamc3 (laminin gamma 3 [Source:MGI Symbol;Acc:MGI:1344394])

HSP 1 Score: 206.068 bits (523), Expect = 1.525e-55
Identity = 141/437 (32.27%), Postives = 202/437 (46.22%), Query Frame = 2

Query:   50 ALNGELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVH-ESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPA----------LTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGR--SFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            A   ++ +CY   G  + C P   N A     EAS TCG    E  C         A   C++C+  DP     +  + D H     T W S  +     YPTSVNLTL L K   I+++ ++     P+   IYK    +  W P+QY++  CQ T+  P                 + FSDI+ L             GG+      + F+  +GR  ++    S   Q W+ +T+I IS  L     +G+ + ++ R  ++  Y++  SD  +GG+  C+GHAS     +     C CQH+T G DCE+C   F D+PW+  T  +   C  C C+ HS +C FD  ++  +G  HG  C  C D+T GP C++C   Y+R        K  C+PC CH  GSLS   CD  SG C CKP VTG  C  C PG+
Sbjct:   26 AAGADMGSCYDGVGRAQRCLPEFENAAFGRRAEASHTCGRP-PEDFCPHVGAP--GAGLQCQRCDDADPGRRHDASYLTDFHSPDDSTWWQSPSMAFGVQYPTSVNLTLSLGKAYEITYVRLKFHTSRPESFAIYKRTYASGPWEPYQYYSASCQKTYGRPEGHYLRPGEDERVAFCTSEFSDISPLN------------GGN------VAFSTLEGRPSAYNFEESPVLQEWVTSTDILIS--LDRLNTFGDDIFKDPRVLQS--YYYAVSDFSVGGRCKCNGHASECEPNAAGQLACRCQHNTTGVDCERCLPFFQDRPWARGTAEDANECLPCNCSGHSEECTFDRELYRSTG--HGGHCQRCRDHTTGPHCERCEKNYYRWSP-----KTPCQPCDCHPAGSLS-LQCDN-SGVCPCKPTVTGWKCDRCLPGF 428

HSP 2 Score: 76.6406 bits (187), Expect = 6.719e-14
Identity = 48/157 (30.57%), Postives = 71/157 (45.22%), Query Frame = 2

Query:  866 ASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNS 1336
            A   I  S D     C     G+ CE C + F   P   +    P  C+RC+C+ +      D N  + +   H   C+ C  NT G  C+ C  G++   A      + C PC C   GS+S   C+ V+G+C C P V+G+ C+ C+PG+    S
Sbjct:  774 ACATIPESGDVVCTHCPPGQRGRRCESCEDGFFGDPLGLSGAPQP--CRRCQCSGN-----VDLNA-VGNCDPHSGHCLRCLYNTTGAHCEHCREGFYGS-AVATRPVDKCAPCSCDLRGSVSEKTCNPVTGQCVCLPYVSGRDCSRCSPGFYDLQS 921

HSP 3 Score: 59.6918 bits (143), Expect = 1.365e-8
Identity = 43/138 (31.16%), Postives = 61/138 (44.20%), Query Frame = 2

Query:  911 CQHSTAGKDCEKCHEEFNDQPWSSATIRNPA-VCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            C ++T G  CE C E F    + SA    P   C  C C+          +V  K+       C+ C     G  C +C+PG+     Y +     C+ C CH +GSL    C   +G+C C+PGVTG+ C  C  G+
Sbjct:  846 CLYNTTGAHCEHCREGF----YGSAVATRPVDKCAPCSCD-------LRGSVSEKTCNPVTGQCV-CLPYVSGRDCSRCSPGF-----YDLQSGRGCQSCKCHPLGSLENK-CHPKTGQCPCRPGVTGQACDRCQLGF 965

[Close]

BLAST of Netrin 1 vs. UniProt/SwissProt
Match: sp|P34710|UNC6_CAEEL (Netrin unc-6 OS=Caenorhabditis elegans OX=6239 GN=unc-6 PE=1 SV=1)

HSP 1 Score: 310.071 bits (793), Expect = 1.181e-95
Identity = 190/598 (31.77%), Postives = 297/598 (49.67%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYI-LTP--KEHYG-----NLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSS-----CDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNRFTRQK 1828
            C+   G P  C P  IN A    + AS TCG N  +  CT      G   + C+ C++ +   S  + ++ D +  G  TCW+S     S  P +V+LTL L K+  ++++++  C   PD + +YK       W+P+Q+++ +C+  F       D   + +  N  + VC      M  GG+   F  +   P   ++F +  S   Q+W+ AT+I++ +  L+P   E YG     N    E  +     Y +   ++ +GG+  C+GHASR I      Y C+C+H+TAG +CE C     D+PW  AT  +   C  C CN H+ +C FD  +F  SG   G  C++C  NT G  C  C PG+ R  + P+ H+ ACK C CH VGSL G  C+Q SG+C CKPGVTG TC  CA GY+Q+ S   PC KI      + S+ S     C  C+   KR+N K+FC ++   ++ + SRE    W ++   +E V+ R  +       N++  E TS+W+    V C C     G  YL++   K      +  L++N   V+ +W++   ++  +F  +DK+G+C   T  +
Sbjct:   37 CHDHTGRPVRCVPEFINAAFGKPVIASDTCGTNRPDKYCTVKEGPDGIIREQCDTCDARNHFQSHPASLLTDLNSIGNMTCWVST---PSLSPQNVSLTLSLGKKFELTYVSMHFCSRLPDSMALYKSADFGKTWTPFQFYSSECRRIFGR-----DPDVSITKSNEQEAVC-TASHIMGPGGNRVAFPFLENRP-SAQNFEN--SPVLQDWVTATDIKVVFSRLSPDQAELYGLSNDVNSYGNETDDEVKQRYFYSMGELAVGGRCKCNGHASRCIFDKMGRYTCDCKHNTAGTECEMCKPFHYDRPWGRATANSANSCVACNCNQHAKRCRFDAELFRLSGNRSGGVCLNCRHNTAGRNCHLCKPGFVRDTSLPMTHRKACKSCGCHPVGSL-GKSCNQSSGQCVCKPGVTGTTCNRCAKGYQQSRSTVTPCIKIPTKADFIGSSHSEEQDQCSKCRIVPKRLNQKKFCKRDHAVQMVVVSREMVDGWAKYKIVVESVFKRGTE-------NMQRGE-TSLWISPQGVICKCPKLRVGRRYLLLG--KNDSDHERDGLMVNPQTVLVEWEDDIMDKVLRFSKKDKLGQCPEITSHR 611

[Close]

BLAST of Netrin 1 vs. UniProt/SwissProt
Match: sp|O95631|NET1_HUMAN (Netrin-1 OS=Homo sapiens OX=9606 GN=NTN1 PE=1 SV=2)

HSP 1 Score: 301.982 bits (772), Expect = 1.424e-92
Identity = 185/606 (30.53%), Postives = 299/606 (49.34%), Query Frame = 2

Query:   41 GLVALNGEL---QTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-----SKLRHLVKSNSSCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            GL    G+      C   NG P+ C P  +N A    +  SSTCG   A        ++  +  +SC  CN+ DPK +     + D +     TCW SE   +  +P +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  +  P     T       N  + VC D    M    GG      LI F+   GR        +   Q+W+ AT+IR+++  +    +G+    +   A +  Y +  SD+ +GG+  C+GHA+R +R  DD+  C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GY+R    PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI     +     V+    CD   + SK   +IN K++C K+   +++I   +  G W +F   I  V+   Q   R+ + +       S+W+    + C C   +    YL++ N + +    Q+ ++ ++S ++  W++TW  +  +F  ++K GKC +
Sbjct:   27 GLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCVVS--ERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQ--FPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQ-----NEQEAVCTDSHTDMRPLSGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAF--SRLHTFGDENEDDSELARD-SYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHILKADKAGDWWKFTVNIISVY--KQGTSRIRRGD------QSLWIRSRDIACKCPKIKPLKKYLLLGNAEDSP--DQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603

[Close]

BLAST of Netrin 1 vs. UniProt/SwissProt
Match: sp|O09118|NET1_MOUSE (Netrin-1 OS=Mus musculus OX=10090 GN=Ntn1 PE=1 SV=3)

HSP 1 Score: 301.212 bits (770), Expect = 2.364e-92
Identity = 184/606 (30.36%), Postives = 300/606 (49.50%), Query Frame = 2

Query:   41 GLVALNGEL---QTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-----SKLRHLVKSNSSCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            GL    G+      C   NG P+ C P  +N A    +  SSTCG   A        ++  +  +SC  CNS DPK +     + D +     TCW SE   +  +P +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  +  P     T       N  + VC D    M    GG      LI F+   GR        +   Q+W+ AT+IR+++  +    +G+    +   A +  Y++  SD+ +GG+  C+GHA+R +R  DD+  C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R    PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI     +     V+    CD   + SK   ++N K++C K+   +++I   +  G W +F   I  V+   Q   R+ + +       S+W+    + C C   +    YL++ N + +    Q+ ++ ++S ++  W++TW  +  +F  ++K GKC +
Sbjct:   27 GLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCVVS--ERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQ--FPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQ-----NEQEAVCTDSHTDMRPLSGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAF--SRLHTFGDENEDDSELARD-SYYYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKMNMKKYCRKDYAVQIHILKADKAGDWWKFTVNIISVY--KQGTSRIRRGD------QSLWIRSRDIACKCPKIKPLKKYLLLGNAEDSP--DQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603

[Close]

BLAST of Netrin 1 vs. UniProt/SwissProt
Match: sp|Q90922|NET1_CHICK (Netrin-1 OS=Gallus gallus OX=9031 GN=NTN1 PE=1 SV=1)

HSP 1 Score: 298.516 bits (763), Expect = 2.672e-91
Identity = 181/593 (30.52%), Postives = 297/593 (50.08%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAES-ICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-----SKLRHLVKSNSSCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            CY  +G P+ C P  +N A    ++ SSTCG+  +   + TE   K  +  +SC  CN+ DPK +     + D +     TCW S+   +  YP +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  +  P+    T       N  + +C D    +    GG      LI F+   GR        +   Q+W+ AT+I++++  +    +G+    +   A +  Y +  SD+ +GG+  C+GHASR +R  DD   C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R  + PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI            +  + CD   + SK   +IN K++C K+   +++I   E    W +F   I  V+ +     R            ++WVH   + C C   +    YL++ +  T +   Q+ +I ++S ++  W++TW  +  +F  ++K GKC +
Sbjct:   43 CYDEHGLPRRCIPDFVNSAFGKEVKVSSTCGKPPSRYCVVTE---KGEEQVRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQ--YPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNKPSRAAITKQ-----NEQEAICTDSHTDVRPLSGG------LIAFSTLDGRPTAHDFDNSPVLQDWVTATDIKVTF--SRLHTFGDENEDDSELARD-SYFYAVSDLQVGGRCKCNGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKECDCHPVGA-AGQTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPAAPPPTAASSTEEPADCDSYCKASKGKLKINMKKYCKKDYAVQIHILKAEKNADWWKFTVNIISVYKQGSNRLRRGD--------QTLWVHAKDIACKCPKVKPMKKYLLLGS--TEDSPDQSGIIADKSSLVIQWRDTWARRLRKFQQREKKGKCRK 605

[Close]

BLAST of Netrin 1 vs. UniProt/SwissProt
Match: sp|Q2HXW4|NET1_PIG (Netrin-1 OS=Sus scrofa OX=9823 GN=NTN1 PE=2 SV=1)

HSP 1 Score: 297.745 bits (761), Expect = 4.901e-91
Identity = 183/600 (30.50%), Postives = 292/600 (48.67%), Query Frame = 2

Query:   41 GLVALNGEL---QTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-----SKLRHLVKSNSSCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDK 1795
            GL    G+      C   NG P+ C P  +N A    +  SSTCG   A        ++  +  +SC  CN+ DPK +     + D +     TCW SE   +  +P +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  +  P     T       N  + VC D    M    GG      LI F+   GR        +   Q+W+ AT+IR+++  +    +G+    +   A +  Y +  SD+ +GG+  C+GHA+R +R  DD+  C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GYFR    PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI     +     V+    CD   + SK   +IN K++C K+   +++I   +  G W +F   I  V+ +     R    NL        W+    + C C   +    YL++ N + +    Q+ ++ ++S ++  W++TW  +  +F  ++K
Sbjct:   27 GLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCVVS--ERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQ--FPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQ-----NEQEAVCTDSHTDMRPLSGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAF--SRLHTFGDENEDDSELARD-SYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYFRDLGKPITHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGVTCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHILKADKAGDWWKFTVNIISVYKQGASRIRRGDQNL--------WIRSRDIACKCPKIKPLKKYLLLGNAEDSP--DQSGIVADKSSLVIQWRDTWARRLRKFQQREK 597

[Close]

BLAST of Netrin 1 vs. TrEMBL
Match: A0A0K0EM36 (Uncharacterized protein OS=Strongyloides stercoralis OX=6248 PE=4 SV=1)

HSP 1 Score: 321.242 bits (822), Expect = 8.081e-98
Identity = 185/588 (31.46%), Postives = 305/588 (51.87%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVY-------HFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLV--KSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTS-MWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
            CY ++G P  C P  IN A    + ASSTCG NG    CT   +  G   + C+ C++     +  + ++ D +     TCWISE   + +   +V LT+ L K+  +++I+++ C   PD + IYK      +W P+Q+++  C     M     D  +T S  N  + +C +   +M        F  +   P    +F    S   Q+W+ AT+IRI +      +     + +  N  + +        ++  +++ +GG+  C+GHASR I      Y C+C+H+TAG DCE+C     D+PW+ AT  +   C  C CN H+ KC F+  ++  SG   G  CI+C  NT G  C  C PGY+R +   I H+ ACK C CH VGSLS + C+Q SG+C CKPGVTG+TC  CA GY+Q+ + + PC KI  +   +  K+N +CD C+   KR+NF+++C ++  F+  I SRE    ++++   IE+V+ +N         + +  +G++ +W+ + +  C C     G  Y+++       +  Q+EL ++   ++ DW ET  E+ ++F  ++K G+C
Sbjct:    9 CYDSSGRPIRCVPDFINAAFGKPVIASSTCGVNGPSRYCTIRENTNGLIREVCDICDNKVKNKAHPASLLTDLNNARNLTCWISEPSIDKN--ENVTLTVSLGKKFELTYISMQFCNKIPDSMAIYKSVDGGKNWIPFQFYSSQC-----MEMYQRDVKDTISPKNEQEAICTN-SHTMSPTASRVAFATLEGRPS---AFRFEQSPILQDWVTATDIRIVFNKPSTFNEQLYAVSDSNNITDDMSGDMIAKSYYSMAELAVGGRCKCNGHASRCIYDKKGQYTCDCKHNTAGNDCERCKPFHYDRPWARATSESANACVACNCNLHARKCRFNAELYRLSGNKSGGICINCRHNTAGRNCHYCKPGYYRDNTKAITHRRACKACGCHLVGSLSKS-CNQTSGQCICKPGVTGQTCNRCAKGYQQSRNPQMPCIKIPTVTQSIIPKNNVNCDKCKVSPKRVNFRKYCKRQHAFQFYIISREILTDYVKYEISIEKVYKKN---------DYKIKKGSNYLWLPEKMAICKCPKLRIGQRYIILGTNNAKNYK-QSELYIDNHSIVVDWSETHVERMARFVRREKNGEC 574

[Close]

BLAST of Netrin 1 vs. TrEMBL
Match: A0A090LSV4 (Netrin-1a OS=Strongyloides ratti OX=34506 GN=SRAE_X000060400 PE=4 SV=1)

HSP 1 Score: 321.242 bits (822), Expect = 8.343e-98
Identity = 187/588 (31.80%), Postives = 302/588 (51.36%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVY-------HFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI--SKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCN 1810
            CY ++G P  C P  IN A    + ASSTCG NG    C    +  G   + C+ C++     +  + ++ D +     TCWISE     +   +V LT+ L K+  +++I+++ C   PD + IYK      +W P+Q+++  C     M     D  +T S  N  + +C +   +M        F  +   P    +F    S   Q+W+ AT+IRI +      +     + +  N  + +        ++  +++ +GG+  C+GHASR I      Y C+C+H+TAG DCE+C     D+PW+ AT  +   C  C CN H+ KC F+  ++  SG   G  CI+C  NT G  C  C PGY+R +   I H+ ACK C CH VGSLS + C+Q SG+C CKPGVTG+TC  CA GY+Q+ + + PC KI  S    + KSN +C+ C+   KR+NF++FC ++  F+  I SRE    ++++   IE+V+ +N  D ++ +          +W+ + +  C C     G  Y+++      +   Q+EL +N   ++ DW ET  E+ ++F  ++K G+C+
Sbjct:    9 CYDSSGRPIRCVPDFINAAFGKPVIASSTCGVNGPSKFCAIRENVNGLIREVCDICDNTIKSKAHPASLLTDLNNARNLTCWISEPSINKN--ENVTLTVSLGKKFELTYISMQFCNKIPDSMAIYKSVDNGKNWIPFQFYSSQC-----MEMYQRDVKDTISPKNEQEAICTN-SHTMSPTASRVAFATLEGRPS---AFRFEQSPILQDWVTATDIRIIFNKPSTFNEQLYAITDSNNITDDISNDMIAKSYYSMAELAVGGRCKCNGHASRCIYDKKGQYTCDCKHNTAGNDCERCKPFHYDRPWARATSESANACVACNCNLHARKCRFNAELYRLSGNKSGGICINCRHNTAGRNCHYCKPGYYRDNTKAITHRRACKACGCHLVGSLSKS-CNQTSGQCICKPGVTGQTCNRCAKGYQQSRNPQMPCIKIASSTQNSIPKSNINCEKCKISPKRVNFRKFCKRQHVFQFYIISREIMTDYVKYEISIEKVYKKN--DYKIKK------GPNYLWLPEKMAICKCPKLRIGQRYMILG-TNNDQDNKQSELYINSHSIVVDWTETLVERMARFVKREKNGECD 575

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BLAST of Netrin 1 vs. TrEMBL
Match: A0A5K3F5Z3 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 327.405 bits (838), Expect = 1.610e-97
Identity = 203/695 (29.21%), Postives = 313/695 (45.04%), Query Frame = 2

Query:   71 TCYSANGDPKPCEPLLINLAQPMHIEASSTCGENG-AESICTEWFDKLGKAHKS-CEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPK-------EHYGN----LLLREKRNA-------ENPVYHFGSSDIMIGGQPL---------------------------------------------------CHGHASRIIR-------------TSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI----------------SKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVW--------------TRNQQDPRVSQ-LNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCN 1810
             CY A+     C P   N+A+ + + A+STCG+ G AE +C  W  + G+  ++ CE C+S     S+ ++ + D HI   +TCW+S  V   S   +VNLTL L KR  I +I+++ CG  PD I +YK       W PWQYF+ DC   F +P  +       S  N  + +C  ++  + Y    ++  +I F+   GR      S    +W+  T+++IS    P        E  G     +L R  R++       + PV+  G   +   G  L                                                   C+GHA+R +R              +    +C+CQH+T G DCE+C   + D+PW+ AT  +   CK C+CNNH+  C+FD N++ KSG   G  C+ CG NT G  C +C  G+ R+  + I+   AC+ C CH +GS+   PCD+ +G+C CK GVTG+TC  C  GYKQT S   PC K                 + +     ++ +C  C++ +KR  FK+FC ++  F+  + S+E+RG+ +R +  I  VW               R  Q P +   + L     TS   H     C C  F+   SYL ++ V    F  + EL+L+Q   I  W E W  +  +F  + + G+C+
Sbjct:   44 VCY-ADNKAYLCTPPFTNIAEGIPVVATSTCGQGGRAERVCKSWTSQNGQKRQTYCETCDSRKAATSRGAERLTDRHITSNQTCWVSGKVAPGS---TVNLTLSLGKRFEIFYISLQPCGPLPDSIALYKSSDFGRTWKPWQYFSTDCYRAFGLPTSSEHNAQ-ISSANIQEVLCVAIKPPVKYNAQGQVSNVIAFSTTIGRPTSQSWSPALIDWMTMTDLQISLSRFPARRKSRTVERSGGDNTVVLHRRDRSSGQRRVPQKAPVFRLGGGRLFHQGAELEEMQADGTTLNATASTATNARNEVNTHEIHHDEDDAVYFAFSDIAVGGRCKCNGHANRCVRDRIVEKNAAGEEIVTWGPLRCDCQHNTVGADCERCAPGYLDRPWARATNEDANECKACQCNNHTTSCMFDINIYRKSGGQSGGVCLGCGQNTEGVNCQECIAGFTRRPGHSIFSLAACQECQCHPIGSIGSRPCDRKTGQCHCKTGVTGQTCNRCLDGYKQTRSKITPCVKAVDALVFAGSATRSSPQTSIVGQPTADDACPPCEKNNKRFRFKKFCRRQAVFRATVISQEARGELVRLVIRIHDVWRNKGSLAQRYLPAHVRRNQAPIIPLWVPLTKKPSTSRESH---AVCVCPRFKIDQSYLFISQVYEIPFHERNELLLDQKSTILPWVENWRRRLMRFAIRQERGRCD 730

[Close]

BLAST of Netrin 1 vs. TrEMBL
Match: V4AN98 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_201560 PE=4 SV=1)

HSP 1 Score: 319.316 bits (817), Expect = 3.770e-97
Identity = 185/587 (31.52%), Postives = 302/587 (51.45%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTF-KMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI--SKLRHLVKSNS---SCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCN 1810
            CY  + +PK C P  +N A  M + ASSTCG   +   C    DK GK  ++C  C++  PK    SK + D +     TCW+SE   +  YP +V LTL L K+  +++I+++ C   PD + IYK       W P+QY++ +C+  + K P+         +  N  + +C +   ++D     +    + F+  +GR        +   Q+W+ AT+I++  +      YG+    E+   E+  Y++  SD  +GG+  C+GHAS+ I   +    C+C+H+TAG DCE+C     D+PWS A+ R    C  C CN H+ +C F+  ++  SG   G  C+ C  NT G  C+ C  GY+R  + PI H+ ACK C CH VG+L G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI  + +R   +  +   SC  C+++S+R++ K+FC ++      + SRE    W++F   +   + R       S ++     GT +WV K  + C C        YL++   K  +   ++  ++++  V+  WK+ W+ +  +F   ++ GKC+
Sbjct:   12 CYE-DSNPKRCIPDFVNAAFGMEVVASSTCGSPPSR-YCKSTTDKEGKIIRNCFICDANHPKRKHPSKYLTDLNNPNNLTCWMSEPFVQ--YPNNVTLTLSLGKKYELTYISLQFCSARPDSMTIYKSVDYGKTWIPFQYYSSNCKEMYNKAPSAIV------TKANEQEALCTEAYSNIDPLSGAR----VAFSTLEGRPSAYAFDHSPVLQDWVTATDIKV--VFNKLNTYGDEEKDEEGARES--YYYSLSDFAVGGRCKCNGHASQCIPLKNGRLGCDCKHNTAGDDCERCKPFHYDRPWSRASAREANECVACNCNLHARQCRFNMELYTLSGYKSGGVCLKCRHNTAGRNCNYCKEGYYRDRSKPITHRKACKACDCHPVGAL-GKTCNQTTGQCPCKDGVTGLTCNRCAKGYQQSKSPIAPCIKIPVTDMRGPNRQPTQEDSCKKCKKRSRRLSIKKFCRRDFAIHAQVVSREKVDDWVKFTINVLNSYKRG-----TSPIDRARRGGTYLWVPKKDLQCKCPKIRLSRRYLIVGKHKRND--SRSGFVIDRKSVVIRWKDKWQRRLRRFVKHERRGKCH 572

[Close]

BLAST of Netrin 1 vs. TrEMBL
Match: A0A0N5C6U6 (Uncharacterized protein OS=Strongyloides papillosus OX=174720 PE=4 SV=1)

HSP 1 Score: 319.316 bits (817), Expect = 3.993e-97
Identity = 187/587 (31.86%), Postives = 298/587 (50.77%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPT-SVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVY-------HFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-SKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
            CY ++G P  C P  IN A    + ASSTCG NG    C       G   + C+ C+      S  + ++ D +     TCWISE    S  P  SV LT+ L K+  +++I+++ C    D + IYK      +W P+Q+++  C     M     ++ +T S  N  + +C +   S+        F  +   P    +F    S   Q+W+ AT+IRI +      +    ++ +  N  + +        ++  +++ +GG+  C+GHASR I      Y C+C+H+TAG DCE+C     D+PW+ AT  +   C  C CN H+ KC F+  ++  SG   G  CI+C  NT G  C  C PGY+R +   I H+ ACK C CH VGSLS + C+Q SG+C CKPGVTG+TC  CA GY+Q+ + + PC KI S    ++K+N  C+ C+   KR+NFK+FC ++  F+  I SRE    ++++   IE+++ +N    R             +W+ + +  C C     G  Y+++      ++  ++EL +N   ++ DW ET  E+ ++F  ++K G C
Sbjct:    9 CYDSSGRPIRCVPDFINAAFGKPVIASSTCGVNGPSKFCAIRESANGLIREVCDICDGAIKSKSHPASLLTDLNNARNLTCWISE---PSINPNESVTLTVSLGKKFELTYISMQFCNRIADSMAIYKSVDGGKNWIPFQFYSSQC-----MEVYGRESKDTISPKNEQEAICTN-SHSLSPTASRVAFATLEGRPS---AFRFEQSPILQDWVTATDIRIVFNKPSAMNEQLYVISDSNNITDEISNDMIAKSYYSMAELAVGGRCKCNGHASRCIYDKKGQYTCDCKHNTAGNDCERCKPFHYDRPWARATSESANACVACNCNLHARKCRFNGELYRLSGNKSGGICINCRHNTAGRNCHYCKPGYYRDNTKAITHRRACKACGCHIVGSLSKS-CNQTSGQCICKPGVTGQTCNRCAKGYQQSRNPQTPCIKIPSPQEGVLKNNVVCEKCKVSPKRVNFKKFCKRQHAFQFYIISREIVADYVKYEISIERIFKKNDYKIR--------KGAQFLWLPEKMAICKCPKLRTGQRYIILGTNNLRDYK-RSELYINNHSIVVDWSETHVEKLARFGRREKNGDC 573

[Close]

BLAST of Netrin 1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029])

HSP 1 Score: 300.827 bits (769), Expect = 2.949e-93
Identity = 182/592 (30.74%), Postives = 293/592 (49.49%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISE-GVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSD-DTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNS-----SCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            CY  +G  + C P  +N A    + ASSTCG  G    C +  DK  +  ++C  C++ DPK +     + D +     TCW SE GV   +   +V LTL L K+  +++++V+ C   PD + I+K       W P+Q+++  C+  F  P     T       N  + VC D        G      L+ F+   GR        +   Q+W+ AT++R+++          L    + + +     +  SD+ +GG+  C+GHASR ++  D     C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GY+R  + PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI        ++S      CD   + SK   +IN K++C K+   +V+I   +  G+W +F   I  V+   Q + R+ + +        +WV    V C C   + G  YL++ N + +   GQ+ ++ ++  ++  W++TW  +  +F  ++K GKC +
Sbjct:   37 CYDEHGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQ--DKGEEGARTCHTCDASDPKRAHPGSYLTDLNNPHNLTCWQSETGVQ--ALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRPNRAAITKQ-----NEQEAVCTDAHAD----GRPLSGGLVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTF--------SRLTAPGEPDEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTTASSPEEPADCDSYCKASKGKLKINMKKYCKKDYAVQVHILKSDKAGEWWKFTVNIISVY--KQGESRIRRGD------QLLWVRAKDVACKCPKIKTGKKYLLLGNDEDSP--GQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 596

[Close]

BLAST of Netrin 1 vs. Ensembl Cavefish
Match: ntn1b (netrin-1-like [Source:NCBI gene;Acc:111191060])

HSP 1 Score: 297.745 bits (761), Expect = 9.912e-92
Identity = 182/592 (30.74%), Postives = 292/592 (49.32%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDT-YQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSS-----CDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVS-QLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
            CY  NG P+ C P  +N A    + ASSTCG   A   C    ++  +  + C  C++ DPK +  +  + D +     TCW SE   +  +P +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  F  P+    T       N  + VC D    M    GG      LI F+   GR        +   Q+W+ AT++R+++  +    +G+    +   A +  Y +  SD+ +GG+  C+GHAS+ ++  D     CEC+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GY+R     I H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI          S+     CD   + SK   ++  K++C K+   +V++   +  G+W +F   I  V+ + +   R   QL         +WV    V C C   + G  YL++ +    +  GQ+ ++ ++  ++  WK+ W  +  +F  +DK GKC
Sbjct:   57 CYDENGQPRRCIPDFVNAAFGKEVRASSTCGAQTAARYCVV-TERGEERSRECHTCDAADPKKAHPAAYLTDLNNPHNLTCWQSESYVQ--HPQNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCKKMFNRPSRAAITKQ-----NEQEAVCTDSHTDMRPLAGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTF--SRLHTFGDENEDDSELARDS-YFYAVSDLQVGGRCKCNGHASKCVKDRDGGGLVCECKHNTAGAECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMTKAISHRRACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVASPTATYTSAEEPTDCDSHCKASKGKMKVTMKKYCKKDFAVQVHVLKGDKAGEWWKFTINIISVYKQGEHRIRRGDQL---------LWVRAKDVACKCPKIKPGKKYLLLGS-DDDDSRGQSGVVADKGSLLIPWKDLWARRLRKFQQRDKRGKC 620

[Close]

BLAST of Netrin 1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029])

HSP 1 Score: 301.212 bits (770), Expect = 1.323e-91
Identity = 182/592 (30.74%), Postives = 293/592 (49.49%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISE-GVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSD-DTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNS-----SCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            CY  +G  + C P  +N A    + ASSTCG  G    C +  DK  +  ++C  C++ DPK +     + D +     TCW SE GV   +   +V LTL L K+  +++++V+ C   PD + I+K       W P+Q+++  C+  F  P     T       N  + VC D        G      L+ F+   GR        +   Q+W+ AT++R+++          L    + + +     +  SD+ +GG+  C+GHASR ++  D     C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GY+R  + PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI        ++S      CD   + SK   +IN K++C K+   +V+I   +  G+W +F   I  V+   Q + R+ + +        +WV    V C C   + G  YL++ N + +   GQ+ ++ ++  ++  W++TW  +  +F  ++K GKC +
Sbjct:  214 CYDEHGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQ--DKGEEGARTCHTCDASDPKRAHPGSYLTDLNNPHNLTCWQSETGVQ--ALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRPNRAAITKQ-----NEQEAVCTDAHAD----GRPLSGGLVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTF--------SRLTAPGEPDEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTTASSPEEPADCDSYCKASKGKLKINMKKYCKKDYAVQVHILKSDKAGEWWKFTVNIISVY--KQGESRIRRGD------QLLWVRAKDVACKCPKIKTGKKYLLLGNDEDSP--GQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 773

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BLAST of Netrin 1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029])

HSP 1 Score: 237.269 bits (604), Expect = 3.340e-68
Identity = 154/584 (26.37%), Postives = 260/584 (44.52%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISE-GVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDT-YQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            CY  +G  + C P  +N A    + ASSTCG  G    C +  DK  +  ++C  C++ DPK +     + D +     TCW SE GV   +   +V LTL L K+  +++++V+ C   PD + I+K       W P+Q+++  C+  F  P     T       N  + VC D        G      L+ F+   GR        +   Q+W+ AT++R+++          L    + + +     +  SD+ +GG+  C+GHASR ++  D     C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GY+R  + PI H+ ACK        + + +P +      +CK    GK                                           +IN K++C K+   +V+I   +  G+W +F   I  V+   Q + R+ + +        +WV    V C C   + G  YL++ N + +   GQ+ ++ ++  ++  W++TW  +  +F  ++K GKC +
Sbjct:  214 CYDEHGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQ--DKGEEGARTCHTCDASDPKRAHPGSYLTDLNNPHNLTCWQSETGVQ--ALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRPNRAAITKQ-----NEQEAVCTDAHAD----GRPLSGGLVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTF--------SRLTAPGEPDEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKACKEIPVAPPTTTASSPEEPADCDSYCK-ASKGKL------------------------------------------KINMKKYCKKDYAVQVHILKSDKAGEWWKFTVNIISVY--KQGESRIRRGD------QLLWVRAKDVACKCPKIKTGKKYLLLGNDEDSP--GQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 723

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BLAST of Netrin 1 vs. Ensembl Cavefish
Match: ntn1b (netrin-1-like [Source:NCBI gene;Acc:111191060])

HSP 1 Score: 232.261 bits (591), Expect = 1.245e-67
Identity = 158/584 (27.05%), Postives = 263/584 (45.03%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDT-YQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVS-QLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
            CY  NG P+ C P  +N A    + ASSTCG   A   C    ++  +  + C  C++ DPK +  +  + D +     TCW SE   +  +P +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  F  P+    T       N  + VC D    M    GG      LI F+   GR        +   Q+W+ AT++R+++  +    +G+    +   A +  Y +  SD+ +GG+  C+GHAS+ ++  D     CEC+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GY+R     I H+ ACK                        +  V   T T+         S + P             +S C   + K K +  K++C K+   +V++   +  G+W +F   I  V+ + +   R   QL         +WV    V C C   + G  YL++ +    +  GQ+ ++ ++  ++  WK+ W  +  +F  +DK GKC
Sbjct:   57 CYDENGQPRRCIPDFVNAAFGKEVRASSTCGAQTAARYCVV-TERGEERSRECHTCDAADPKKAHPAAYLTDLNNPHNLTCWQSESYVQ--HPQNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCKKMFNRPSRAAITKQ-----NEQEAVCTDSHTDMRPLAGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTF--SRLHTFGDENEDDSELARDS-YFYAVSDLQVGGRCKCNGHASKCVKDRDGGGLVCECKHNTAGAECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMTKAISHRRACK------------------------EIPVASPTATY--------TSAEEP----------TDCDSHCKASKGKMK-VTMKKYCKKDFAVQVHVLKGDKAGEWWKFTINIISVYKQGEHRIRRGDQL---------LWVRAKDVACKCPKIKPGKKYLLLGS-DDDDSRGQSGVVADKGSLLIPWKDLWARRLRKFQQRDKRGKC 570

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BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009682.1 (pep scaffold:Pmarinus_7.0:GL479835:738:11671:-1 gene:ENSPMAG00000008750.1 transcript:ENSPMAT00000009682.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 156.377 bits (394), Expect = 8.950e-43
Identity = 101/324 (31.17%), Postives = 162/324 (50.00%), Query Frame = 2

Query:  395 ISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTF-------------KMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGR--SFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            I+++ ++     P+   IYK  S    W+P+QY++  C+ T+             +   L TD    FSDI+ L             GG+      + F+  +GR  ++    S   Q+W+ +TEIR++  L     +G+ +  + +   +  Y++  SD  +GG+  C+GHAS  ++       C+C+H+T G DCEKC   +ND+PW  AT  +   C  C+CN  + +C FD  ++  +G  HG  C +C DNT G  C++C   ++R+ A        C PC C+ VGS S   CD+  G+C CK GV G+ C  C PG+
Sbjct:    6 ITYVRLKFHTSRPESFAIYKRASMDGPWTPYQYYSGSCEPTYGKRNRGFLRSGDDEQTPLCTDE---FSDISPLT------------GGN------VAFSTLEGRPSAYNFDNSPVLQDWVTSTEIRVT--LNRLNTFGDEVFNDHKVLRS--YYYAISDFAVGGRCKCNGHASECVKNELGALACKCRHNTMGADCEKCLPLYNDRPWHRATSESANECTLCDCNGRADECYFDPELYRATG--HGGHCTNCRDNTDGKTCERCLENFYRRSA-----SEHCLPCNCNPVGSYS-RQCDE-QGRCSCKQGVMGERCDQCLPGF 295

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BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004606.1 (pep scaffold:Pmarinus_7.0:GL477874:5526:15188:-1 gene:ENSPMAG00000004198.1 transcript:ENSPMAT00000004606.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 100.138 bits (248), Expect = 1.969e-24
Identity = 61/211 (28.91%), Postives = 100/211 (47.39%), Query Frame = 2

Query:  395 ISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPAL----------TTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKN---EQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSAT 988
            I+++ +      P+   IYK  S    W P+Q+++  C+ TF +P+           T    + FSDI+ L             GG+      + F+  +GR        N   +Q W+ AT++R+S  L     +G+ +  + +   +  Y++  SD+ +GG+  CHGHAS   R SD    C CQH+T G DCE+C    N +PW+ A+
Sbjct:    8 ITYVRLRFHTSRPESFAIYKRTSPASPWQPYQFYSGTCERTFGLPSRGFLRAGDEERTALCSDEFSDISPLT------------GGN------VAFSTLEGRPGALAFDGNDKLQQEWVTATDVRVS--LRRLNTFGDEVFGDPKVLRS--YYYAVSDLAVGGRCKCHGHASECGRGSDGRLVCRCQHNTTGDDCERCLPSHNSRPWAQAS 196

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BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004614.1 (pep scaffold:Pmarinus_7.0:GL477874:5547:15173:-1 gene:ENSPMAG00000004198.1 transcript:ENSPMAT00000004614.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 98.2117 bits (243), Expect = 7.790e-24
Identity = 63/209 (30.14%), Postives = 100/209 (47.85%), Query Frame = 2

Query:  395 ISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPAL----------TTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQG--RSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSA 985
            I+++ +      P+   IYK  S    W P+Q+++  C+ TF +P+           T    + FSDI+ L             GG+      + F+  +G   S G  LS   Q W+ AT++R+S  L     +G+ +  + +   +  Y++  SD+ +GG+  CHGHAS   R SD    C CQH+T G DCE+C    N +PW+ A
Sbjct:    3 ITYVRLRFHTSRPESFAIYKRTSPASPWQPYQFYSGTCERTFGLPSRGFLRAGDEERTALCSDEFSDISPLT------------GGN------VAFSTLEGLFHSTGP-LSSATQEWVTATDVRVS--LRRLNTFGDEVFGDPKVLRS--YYYAVSDLAVGGRCKCHGHASECGRGSDGRLVCRCQHNTTGDDCERCLPSHNSRPWAQA 188

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BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008925.1 (pep scaffold:Pmarinus_7.0:GL476496:30277:70426:-1 gene:ENSPMAG00000008054.1 transcript:ENSPMAT00000008925.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.99 bits (258), Expect = 3.666e-23
Identity = 88/346 (25.43%), Postives = 141/346 (40.75%), Query Frame = 2

Query:  395 ISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFA---KDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISY--ILTPKEHYGNLLLREKRNAENPV---YHFGSSDIMIGGQPLCHGHASRIIRTSD-DTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNV------FLKSGRIHGSS-CIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPC-----------DQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPC 1351
            ++++ V+       G  I +   +   + PWQY++    +C   + +     + V    D    + +C      +      K+   +      GR   D  S    ++ +A  IR+    I T       L  R+ R  +  V   Y++   DI +GG  +C GHAS      D    +C+C+H+T G++C+ C   +N + W   TI N   C++C C+  +  C +D  V          GR  G   C++C  NT G  C+ C  G++R           C+ C C   GSLS   C           D   G+C C+PG  G+ C  CA  Y+     K PC
Sbjct:    5 VAYVIVKAANSPRPGNWILERSLDGATYHPWQYYSVSDSECLTRYGITPTVGNPVYRRDD----EVICTSYYVVLLMLARGKIHTSL----INGRPSADDPSPKLLDFTSARYIRLRLQRIRTLNADLMTLSHRDPREVDPIVTRRYYYSIKDISVGGMCICSGHASTCPWNEDTQKMECQCEHNTCGENCQHCCPGYNQRRWRPGTINNGNTCEKCNCHGKTEDCYYDAEVDRTNRSLSVHGRFSGGGVCVNCSANTAGTNCETCRDGFYRPTGVLPNDPYPCRLCQCDPQGSLSQV-CIKDEKHADPEKDLSPGQCLCRPGFAGERCERCAFAYRGYPDCK-PC 340

HSP 2 Score: 71.2478 bits (173), Expect = 4.647e-13
Identity = 53/191 (27.75%), Postives = 82/191 (42.93%), Query Frame = 2

Query:  848 PLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRI---HGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKN----PCRKISKLRHLVKSNSSC 1399
            P CH    R + T D     +C     G  CE+C ++F  +P S         C+RCECN +              GR+       C+ C + T G  C++CA G++            C+PC CH  G+ +   CD+++G+C C+P V G+TC  CA G+   +S       PC  +        ++  C
Sbjct:  692 PTCH-QDPRGVLTCD-----QCLPGYIGLRCERCADDFFGEPSSPG-----GSCRRCECNGNEEA--------WGGGRVCDARTGQCLRCRERTAGFHCERCADGFYGDAT----GTGGCQPCQCHPEGA-TAPQCDRINGQCPCRPSVVGRTCEQCAIGFYGLSSGAGCSPCPCHPVGTAGVACSADGRC 858

HSP 3 Score: 58.151 bits (139), Expect = 5.955e-9
Identity = 47/143 (32.87%), Postives = 66/143 (46.15%), Query Frame = 2

Query:  896 TYQC-ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            T QC  C+  TAG  CE+C + F    +  AT      C+ C+C+              +  RI+G     C  + VG  C+QCA G+     Y +     C PC CH VG+ +G  C    G+C C PGV G++C  C  G+
Sbjct:  756 TGQCLRCRERTAGFHCERCADGF----YGDAT--GTGGCQPCQCHPEGA-------TAPQCDRINGQ--CPCRPSVVGRTCEQCAIGF-----YGLSSGAGCSPCPCHPVGT-AGVAC-SADGRCHCWPGVEGRSCDRCTSGH 876

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BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007784.1 (pep scaffold:Pmarinus_7.0:GL477336:382472:417638:1 gene:ENSPMAG00000007035.1 transcript:ENSPMAT00000007784.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 92.4337 bits (228), Expect = 1.172e-19
Identity = 77/305 (25.25%), Postives = 128/305 (41.97%), Query Frame = 2

Query:  254 PKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTS-VNLTLGLKKRSL-ISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKM----PALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNE-QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPV--YHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCEC--QHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSG---RIHGSSCIDCGDNTVG 1126
            P++S  ++ +   +     T W+S        P   V +++ L+  S  + ++ V+     P+G+ I +  +    W  WQ FAKDC   + M    P    D+VN           C    + +        F ++   P     +    +    Q ++ A E+R+  +L  +      LL     A  P+  YH   S++++ G+  CHGHA R   +S   Y+C C  Q +T G +CE C   F D+PW +   RN   C+ C C   ++ C ++  +    G   R  G  C DC  NT G
Sbjct:   71 PRVSPHARPLSHVNDDDASTVWVSAPSPGPGQPPPSVAVSIELRGGSYQVFYVIVQFLSPQPEGVRIQRRPAAGSPWVDWQVFAKDCVSMYNMSKNGPLEKPDSVN-----------CLQFPREVPLSRGNVTFSVLTPEPNLRPGYNAFYATPALQAFVLAAEVRV--LLEGR------LLGVAGVAGGPLRPYH-AVSEVIVSGRCECHGHAERC-DSSTTPYRCLCSAQSNTEGPNCELCRPLFRDKPWRAGDTRNQNACRPCLCYGRALSCRYEAILDPHPGLHWRGGGGVCQDCTQNTTG 354

HSP 2 Score: 50.8322 bits (120), Expect = 9.386e-7
Identity = 35/102 (34.31%), Postives = 48/102 (47.06%), Query Frame = 2

Query: 1076 GRIHGSSCID-------CGDNTVGPQCDQCAPGYFRQHAYPIYHKNA--CKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCR 1354
            GR +G++  D       C     G  C  C PG     +Y +   NA  C+PCLC   G+  GT CD  SG+C C PG  G+ C+ C  G+ +     + CR
Sbjct:  591 GRTNGTAGCDARTGRRHCKALASGSLCSLCRPG-----SYNLSETNAAGCEPCLCDPQGTEFGTVCDGSSGQCACLPGWAGRRCSTCQAGFYRLEGDASGCR 687

[Close]

BLAST of Netrin 1 vs. Ensembl Nematostella
Match: EDO36836 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHI5])

HSP 1 Score: 234.958 bits (598), Expect = 2.540e-69
Identity = 166/594 (27.95%), Postives = 266/594 (44.78%), Query Frame = 2

Query:   62 ELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFD--LEKSMDYGGDEKLFRLIPFNPRQGRSFGDVL--SKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNS------SCDFCQRKSKRINFKRFCSKETNFKVNIKSRESR--GQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
            + + CY+     + C+P   +LA    +  S TCGE  +   C     +      +C  C+  + K S  +K + D H     TCW ++ V       +V L L   K   I++++++ CG  PD + IYK       W  +Q+++  C+   KM    T+     S  N    +C D  L + + YGG       I F+  +GR     +  S   Q W+ AT+I++ +         N++ R  R  ++   ++  S+  +GG+  C+GHAS  +   +    C+C+H+T G DC  C   FND+PW  AT  +   CK C CN H+  CVF   +F  SG   G  C+ C  NT G  C  C  G+++     I H   C+ C CH  GS  G  C+Q +G+C CK GV G++C  CAPGYK T S   PC +   +    +S++       C  C+R   ++  KRFC K+   KV +   E +    W+R    I  ++       + S+          +W+ K    C C   + G SY +  N++      +  ++LN   V+  W E   ++  +F    +   C
Sbjct:    1 QAKDCYNEFNRAQLCQPAFHDLAYNKDVYVSHTCGEK-SRRFCPPMSVR---GRTACGFCDERNAKTSHPAKYLTDVHNENNVTCWQADPVQSRE---NVTLILSFGKTYDITYVSLQFCGIRPDSMGIYKSMDYGKSWQAYQFYSSRCE---KMYGRVTN--GEISPENEQVALCTDGHLLRPL-YGGR------IAFSTLEGRPSASKMDYSAVMQEWVMATDIKVEF---------NMISRSARPRDS--LYYAVSEFNVGGRCHCNGHASECVSDRNGRQVCDCKHNTVGVDCGACRPFFNDRPWRPATHHSANECKMCNCNLHARTCVFSMELFKLSGGRSGGVCVKCRHNTAGRYCHYCREGFYKDPNKHITHIKVCRQCNCHPHGS-RGRVCNQSTGQCPCKEGVVGRSCDKCAPGYKSTKSNIVPCIETPNVVMSQESSTPRSRDQGCSQCRRVPLKV--KRFCRKDFALKVTVVRVEKKLPNSWVRATVNINTLF-------KRSRTRRVRRGDGYVWIKKRDFRCRCPKLKPGRSYFIAGNLRGQS--RKRSIVLNGRSVVLPWNEKLLKRIYRFIKLQRNNNC 552

[Close]

BLAST of Netrin 1 vs. Ensembl Nematostella
Match: EDO36523 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF3])

HSP 1 Score: 191.43 bits (485), Expect = 3.197e-51
Identity = 161/579 (27.81%), Postives = 249/579 (43.01%), Query Frame = 2

Query:   59 GELQT-CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDI-NSLKPVCFDLEKSMD-YGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRT----SDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY---------------KQTNSLKNPCRKISKL---RHLVKSNSSCDFCQRKSKRINFKR-------FCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFM 1699
            G+LQ  CY + G  + C P   N A    + +++TCG+   +  C +    + +  K CE CNS DP L   +  + D       T W SE + E+     V LTL L K   +S+I +      P+ + IYK  + +  W P+QYF+  C+ T+ +      T N   D  N    +C D   ++    G    F  +   P    +F +  S   Q W+ A  +RI   L     +G+ +  +     +  Y++   D+ IGG+  C+GHAS    T         QC+CQH T G DCE+C   +ND+PW+ A+ RN   C RC CN  +  CVFD  ++ ++G  HG  C +C  NT GP C++C   ++R+ +        C  C C+ VGS+S   C+   G+C CKPGVTG  C  C   Y                 T+  K  C +  +    RH+V   + C  C+     +           FC   +          SR     F + +E     N Q      +++ +    S++    LV  G     +G ++  M  V T + M
Sbjct:   15 GQLQIQCYDSQGRAQRCMPQFGNAAFGKRVISNNTCGDP-PKKFCVQ--TGVLEVRKECEMCNSSDPALEHPALKITDIKDDTNRTWWQSETLLENP-DKPVTLTLDLGKSYDVSYIRIRFRSPRPESMAIYKKTTPSSKWIPYQYFSATCEKTYGV------TTNGIVDPRNQQVALCTDAFSTITPLTGGNVAFSTLEDRP-DAYNFDN--SPALQEWVTAVAVRIH--LRRMNTFGDEVFGDPNVLRS--YYYAIIDLSIGGRCKCNGHASECEETRLWDGQTRLQCKCQHDTEGVDCERCKPLYNDRPWARASSRNANECVRCNCNGLAESCVFDEALYRQTG--HGGRCQNCKQNTDGPNCERCKENFYRKTSL-----EPCVACGCNPVGSVS-LQCNS-EGQCRCKPGVTGIKCDKCQANYFGFSQTGCRPCQCFGPGTDPAKTQCNEKGECTCKRHVV--GAKCTLCRSGYFGLEASNPHGCKQCFCYGHSTVCKAAPGYTSRNITTDFTTGLEGWAVENDQGDSAGFVSVTAIGKESLFARASLVYIGNRRSSYGQTFGFMFRVGTVDGM 565

HSP 2 Score: 61.6178 bits (148), Expect = 9.030e-10
Identity = 52/175 (29.71%), Postives = 73/175 (41.71%), Query Frame = 2

Query:  866 ASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTV-GP--QCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGT--------PCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKN--PC 1351
             +R I+   +    +C     G  C+ C + +   P        P  C++C C+ +      D N      R+ G  C+ C  NT  GP  QC+ CA GY+    +  Y K  CK C C+  G++S          PCD   G+C C P V+G  C  C P Y    S K   PC
Sbjct:  758 GTRCIQIGANVVCTDCPEGHVGNLCDMCQDGYYGDPMGKRGA--PTTCQKCNCSGN-----IDPNAIGSCDRLTGD-CLKCIHNTRNGPISQCELCAIGYYGNATH--YPKPQCKACECYVQGTVSPPGHDPTLPFPCDD-KGRCTCLPNVSGDKCDTCRPEYWNVASGKGCEPC 921

HSP 3 Score: 50.0618 bits (118), Expect = 3.369e-6
Identity = 41/154 (26.62%), Postives = 68/154 (44.16%), Query Frame = 2

Query:  860 GHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            GH   +    DD  +C C  + +G  C+ C  E+    W+ A+ +    C+ C C+       ++    + +G+ H      C     G +CDQC+  ++       + +  C  C C+  GSL+ T CD+  G C C+PGV G  C  C   +
Sbjct:  876 GHDPTLPFPCDDKGRCTCLPNVSGDKCDTCRPEY----WNVASGKG---CEPCNCDTTG---SWNNTCSVTTGQCH------CKPGVTGRRCDQCSIDHY------AFSELGCLACNCNLQGSLNVT-CDE-QGVCQCRPGVLGIKCDSCQENF 1005

[Close]

BLAST of Netrin 1 vs. Ensembl Nematostella
Match: EDO39502 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9X8])

HSP 1 Score: 168.318 bits (425), Expect = 1.614e-43
Identity = 126/436 (28.90%), Postives = 195/436 (44.72%), Query Frame = 2

Query:   68 QTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICT-EWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDS-HIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGD-EKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRII------RTSDDTY-QCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQ--------VSGKCFCKPGVTGKTCTHCAPGY 1321
            ++CY A GD      LL+   +   I ASSTCG  G E  C        G  H    +    +P+ S   K ++ S   R K+  W SE   E+ Y     L L L+     + + +      P G++I +       W  ++YF+ DC   F  P +         D+     +C +   +++   + E +FR +    +      +  S   QN L  T IRI++  T     G+ LL + R      Y++   D++I G   C+GHA + +       T    Y +C C H+T GK+CE+C + + D PW  A   NP  C++C CN H++KC FD  V+  SG + G  C DC  NTVG  C++C P +++  +      +AC  C C   G ++G  C+         V+G+C CK  V G  C  C  G+
Sbjct:   21 RSCYPATGD------LLV--GRENKIYASSTCGLRGPEEYCVVSNLQDYGDCHICDSRPYQTNPQFSHVPKYMLSSFDGRKKDEWWQSENGRENVY-----LQLDLESEFHFTHLIMRFRTFRPAGMVIERSWDYGKKWQIYRYFSADCDKIF--PGIPKGEPKDIDDV-----ICTNKYSTVEPSTNGEVIFRAL----KSQIPIKNAYSSKVQNLLKITNIRINF--TKLHTLGDDLL-DPRPEIKRKYYYAVYDLVIRGSCSCYGHAEQCLPEPGQPTTPGMVYGRCNCTHNTTGKNCERCQDGYFDVPWRPADADNPNECRKCNCNGHAVKCRFDPAVYQASGNVSGGVCQDCEHNTVGRNCERCKPLHYQDPSKKFSDPDACIACNCDPTGGVNGGECEAKNDPAAGLVAGRCICKRNVGGVRCDRCKAGF 429

HSP 2 Score: 74.3294 bits (181), Expect = 1.093e-13
Identity = 54/160 (33.75%), Postives = 76/160 (47.50%), Query Frame = 2

Query:  854 CHGHASRIIRTSDDTYQC-ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSS-CIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLC-HSVGSLSGTPCDQVSGKCF-CKPGVTGKTCTHCAPGY 1321
            C+GHAS     +  T  C +CQH+T GK+CE C   F    +  AT   P  CKRC+C   S    F  + ++ +     S  C  C     G QC++CA GY+     P+    +CKPC C +++       CD+++G C  C     G  C  C PGY
Sbjct:  852 CYGHASSC---NPKTGVCVDCQHNTVGKNCEACAVGF----YGIATKGTPNDCKRCQCPGGSSGNKFSESCYVDTSTTPPSVLCDKCQVGYTGRQCEECADGYY---GNPLVPGGSCKPCSCNNNIDPTVSGNCDRLTGSCLQCLYNTAGFNCERCKPGY 1001

HSP 3 Score: 66.6254 bits (161), Expect = 2.363e-11
Identity = 46/140 (32.86%), Postives = 62/140 (44.29%), Query Frame = 2

Query:  908 ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSG--TPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            +CQ    G+ CE+C + +   P           CK C CNN+      D  V     R+ GS C+ C  NT G  C++C PGYF            C  C+C   G+  G    C+  +G+C C P V GK C  CA G+
Sbjct:  930 KCQVGYTGRQCEECADGYYGNPLVPG-----GSCKPCSCNNN-----IDPTVSGNCDRLTGS-CLQCLYNTAGFNCERCKPGYFGDAI-----ARNCTSCVCDKKGTNPGFHYSCNHKTGQCNCLPDVEGKQCDRCAEGF 1053

HSP 4 Score: 49.2914 bits (116), Expect = 5.359e-6
Identity = 47/156 (30.13%), Postives = 61/156 (39.10%), Query Frame = 2

Query:  896 TYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHK---NACKPCLCHSVGS-----------LSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            T QC+C++  +G+ C  C       P          +C+ C C  H+  C     V           C+DC  NTVG  C+ CA G+     Y I  K   N CK C C    S            S TP   +  K  C+ G TG+ C  CA GY
Sbjct:  820 TGQCQCRNWASGRQCSLCPPNMWGFP----------LCRPCRCYGHASSCNPKTGV-----------CVDCQHNTVGKNCEACAVGF-----YGIATKGTPNDCKRCQCPGGSSGNKFSESCYVDTSTTPPSVLCDK--CQVGYTGRQCEECADGY 947

HSP 5 Score: 48.9062 bits (115), Expect = 7.217e-6
Identity = 54/219 (24.66%), Postives = 79/219 (36.07%), Query Frame = 2

Query:  854 CHGHASRIIRTSDDTYQC----------ECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCEC------NNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGS-------------------------------LSGTP-----------------CDQVSGKCFCKPGVTGKTCTHCAPG 1318
            C+GHA +  R     YQ           +C+H+T G++CE+C       P  S    +P  C  C C      N    +   D    L +GR     CI C  N  G +CD+C  G+F        + + CK C C+ +G+                               LS TP                 CD+ +G+C C+ G+TG+ C     G
Sbjct:  322 CNGHAVKC-RFDPAVYQASGNVSGGVCQDCEHNTVGRNCERCKPLHYQDP--SKKFSDPDACIACNCDPTGGVNGGECEAKNDPAAGLVAGR-----CI-CKRNVGGVRCDRCKAGFFN---LTTDNPDGCKACGCNPLGTIGECNPDTGRCTCKRYVEGEDCDRCASEYWGLSSTPAGCSNCACDVGGSYDNQCDKQTGQCRCRKGITGRQCERVKTG 528

[Close]

BLAST of Netrin 1 vs. Ensembl Nematostella
Match: EDO46759 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNY2])

HSP 1 Score: 126.716 bits (317), Expect = 2.933e-30
Identity = 94/333 (28.23%), Postives = 148/333 (44.44%), Query Frame = 2

Query:  395 ISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRL---IPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRII-----RTSDDTYQCECQHST--AGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRI---HGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSG-TPCDQV-SGKCFCKPGVTGKTCTHCAPGYKQTNSLKNP 1348
            I F+ +   G  P+ I+I +       + PWQYFA DCQ +F M        N  + +N     C   ++ + Y      F+L   IP  P          S    +++ A+ +RI       + Y + L++ +++      +F    +++ G+  CHGHA ++       +S    +CEC  ST   G+ CE C   +N++ +   T  +P  C +CECNNH+  C ++ ++           G  CI+C  NT G  C  C   +FR+    +   + C PC C   G  +G T C +V SG C CK  V   TC  C  GY   +S  NP
Sbjct:  334 IFFVIMVFYGPPPEAILIERSRDRGSTYEPWQYFASDCQSSFGME-------NNGNLVNPDSINCIQYQRPLPYSSATIAFKLERSIPARPFGAPCSNLYCSTRFLDFIKASNVRI-------QLYNHTLIQNEKHR-----YFALKRVLVTGRCECHGHAQKVTFIKGNSSSPGRCRCECDPSTFTQGEKCESCLPMYNNKAFLRGTNDDPYPCVKCECNNHATACYYNSSLDPSPASRTVGGGGVCINCLHNTAGQFCHVCRDDFFREPGKSLSAVDVCSPCQCTGPGVETGKTSCARVSSGNCTCKKYVREPTCGQCMKGYFNLSS-SNP 646

HSP 2 Score: 54.6842 bits (130), Expect = 9.313e-8
Identity = 42/144 (29.17%), Postives = 60/144 (41.67%), Query Frame = 2

Query:  911 CQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSG--TP-----CDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            C H+TAG+ C  C ++F  +P  S +  +  VC  C+C    ++            R+   +C  C      P C QC  GYF   +    +   C+ C C+  G+L G  TP     C   +GKC C   V G  C  C   Y
Sbjct:  565 CLHNTAGQFCHVCRDDFFREPGKSLSAVD--VCSPCQCTGPGVE-----TGKTSCARVSSGNCT-CKKYVREPTCGQCMKGYFNLSSS---NPEGCQACNCNPKGTLGGDRTPAGELECSGSNGKCACLTNVQGLRCDKCVSAY 697

[Close]

BLAST of Netrin 1 vs. Ensembl Nematostella
Match: EDO36500 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF5])

HSP 1 Score: 126.716 bits (317), Expect = 3.996e-30
Identity = 119/445 (26.74%), Postives = 182/445 (40.90%), Query Frame = 2

Query:   44 LVALNGE----LQTCYSAN-GDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISE--------GVHESSYPTSVNLTLGLKKRSLIS-FITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKM-PALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDE-KLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHA---SRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGY 1321
            +V LN +     +TCY  + G   PC P    ++   ++  S+TCG   A+       +       +    N   P  +     +V      K T W S+        G+     P  VN+TL   KR  +S  I        P  +   K +     W     +A  C   + M P    D  N F      K  C +     +Y G E +   ++ F   +     D  +   Q++L+ T++R+       +  G  LL +     N +Y +  S++ + G+  C+GHA   S  I +     +CEC+H+T G DCE C   FN++PW  A   +   C+ C CNNH+  CV  +N  L  G      C  C  NT G  C  C   ++R  + PI H NAC     +       T  +Q+ G+C CKP V G+ C  C PG+
Sbjct:   18 VVCLNSQNTCRFETCYERDTGRATPCMPFTSFMSLTRNVTTSNTCGTTRAKYCELPGPEPCYYCDANSSNSNEQHPVTNLVDNELVLPFYAQKYTWWQSQTWWETNQLGLSSIENPPKVNITLSFGKRYQLSGHIKATFYSKRPKAMCFDKSNDFGHTWETLLCYAWRCDRFYNMEPQSNPDPANPF------KLYCTE-----EYSGHEPRKLGIVEFIASKRYEICDYFNPEVQDYLSVTDVRLRLEYPASD--GMELLYQDEQTLNKLY-YAISNVEVTGRCSCNGHAMGCSGPIMSR----RCECEHNTMGTDCEMCEPLFNNRPWMRANQTHGNECQECNCNNHATSCV--YNETLGYGL-----CKGCQHNTQGDHCQNCTAKHYRDLSKPINHVNACLGITNNGSCLTQATDTEQI-GQCSCKPNVYGRRCDQCIPGH 436

HSP 2 Score: 60.8474 bits (146), Expect = 1.705e-9
Identity = 48/153 (31.37%), Postives = 69/153 (45.10%), Query Frame = 2

Query:  902 QCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFL--KSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSL--SGTPCDQVSGKCFCKPG--VTGKTCTHCAP-GYKQTNSL 1339
            + EC  +  G  CE C E +  QP           C  C CN+ S  C  +  V    K G  HG  C  C +N  GP+C +C P Y+         K+ CK C C+  G+L  + + CDQ +G+C C     + G+ C  C    Y +++SL
Sbjct: 1073 RAECHRNYTGLSCEVCAEGYTRQPMGGTPFDR---CVLCSCNDRSRFCHPETGVCTDCKIG-THGYRCELCTNNVQGPECVRCKPQYWG------LSKDGCKACDCNLPGTLYSNTSVCDQTTGQCSCNATLHIGGQLCDRCEENAYNKSDSL 1215

[Close]

BLAST of Netrin 1 vs. Ensembl Medaka
Match: NTN1 (netrin-1 [Source:NCBI gene;Acc:101155405])

HSP 1 Score: 303.138 bits (775), Expect = 5.166e-94
Identity = 179/592 (30.24%), Postives = 297/592 (50.17%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSS-----CDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            CY  +G+P+ C P  +N A    ++ SSTCG+  +        +K  +  ++C  C++ DPK       + D +     TCW SE   +  YP +V LTL L K+  +++++++ C   P+ ++IYK       W P+Q+++  C+  +  P     T       N  + VC D    M    GG      LI F+   GR        +   Q+W+ AT+I++  + +    +G+    +   A +  Y +  SD+ +GG+  C+GHASR ++  D +  C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R  + PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI        ++S+     C+   + SK   +IN K++C K+   +V+I   +  G+W +F   I  V+ + +   R     L        WV    V C C   + G  YL++ N + +    Q+ ++ ++  ++  W++TW  +  +F  ++K GKC +
Sbjct:   38 CYDEHGNPRRCIPDFVNAAFGKEVKVSSTCGKTPSRYCVVTSAEKGEERTRNCHSCDASDPKKYHPPAYLTDLNNPHNLTCWQSENFIQ--YPQNVTLTLSLGKKFEVTYVSLQFCSPRPESMVIYKSMDNGKTWVPFQFYSTQCRKMYNKPNRAVITKQ-----NEQEAVCTDSHTDMYPLTGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKV--VFSRLHTFGDENEDDSELARD-SYFYAVSDLQVGGRCKCNGHASRCVKDRDGSLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVSPPTTPASSTEEASDCESYCKASKGKLKINMKKYCKKDYAVQVHILKADKMGEWWKFTVNIISVYKQGESRIRRGDQFL--------WVRAKDVACKCPKIKPGKKYLLLGNDEVSP--SQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 602

[Close]

BLAST of Netrin 1 vs. Ensembl Medaka
Match: ntn1b (netrin-1 [Source:NCBI gene;Acc:101161061])

HSP 1 Score: 295.819 bits (756), Expect = 2.745e-91
Identity = 184/591 (31.13%), Postives = 291/591 (49.24%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-----SKLRHLVKSNSSCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVS-QLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
            CY  NG+P+ C P  +N A    +  SSTCG N A   C    +K  +  + C  C+S DPK +     + D +     TCW SE   +  YP +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  +           T +  N  + +C D    M    GG      LI F+   GR        +   Q+W+ AT+I++  I +    +G+    +   A +  Y +  SD+ +GG+  C+GHAS+ ++  +    CEC+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GYFR  + PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI     +      +  S CD   + SK   +I  K++C K+   +V++   +  G+W +F   I  V+ + +   R   QL         +WV    V C C   + G  YL++      +  G + ++ ++  ++  WK+ W  +  +F  +DK GKC
Sbjct:   40 CYDENGNPRRCIPDFVNSAFGKDVRVSSTCG-NPAARFCVV-SEKGEERTRDCHTCDSNDPKKAHPPAYLTDLNNPHNLTCWQSETYVQ--YPQNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKSWVPFQFYSTQCKKMY-----NRQNKATITKQNEQEAICTDSHTDMHPLTGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKV--IFSRLHTFGDENEDDSELARDS-YFYAVSDLQVGGRCKCNGHASKCVKDREGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYFRDMSKPISHRRACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVASPTSTYSSYEEPSDCDSYCKASKGKMKITMKKYCKKDYAVQVHVLKGDKAGEWWKFTVNIISVYKQGRHRIRRGDQL---------LWVRAKDVACRCPKIKPGRKYLLLGT--DDDSPGHSGVVADKGSLLIPWKDLWGRRLRKFQQRDKRGKC 600

[Close]

BLAST of Netrin 1 vs. Ensembl Medaka
Match: ntn1b (netrin-1 [Source:NCBI gene;Acc:101161061])

HSP 1 Score: 295.819 bits (756), Expect = 3.298e-91
Identity = 184/591 (31.13%), Postives = 291/591 (49.24%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI-----SKLRHLVKSNSSCDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVS-QLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKC 1807
            CY  NG+P+ C P  +N A    +  SSTCG N A   C    +K  +  + C  C+S DPK +     + D +     TCW SE   +  YP +V LTL L K+  +++++++ C   P+ + IYK       W P+Q+++  C+  +           T +  N  + +C D    M    GG      LI F+   GR        +   Q+W+ AT+I++  I +    +G+    +   A +  Y +  SD+ +GG+  C+GHAS+ ++  +    CEC+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  GYFR  + PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI     +      +  S CD   + SK   +I  K++C K+   +V++   +  G+W +F   I  V+ + +   R   QL         +WV    V C C   + G  YL++      +  G + ++ ++  ++  WK+ W  +  +F  +DK GKC
Sbjct:   41 CYDENGNPRRCIPDFVNSAFGKDVRVSSTCG-NPAARFCVV-SEKGEERTRDCHTCDSNDPKKAHPPAYLTDLNNPHNLTCWQSETYVQ--YPQNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKSWVPFQFYSTQCKKMY-----NRQNKATITKQNEQEAICTDSHTDMHPLTGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKV--IFSRLHTFGDENEDDSELARDS-YFYAVSDLQVGGRCKCNGHASKCVKDREGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYFRDMSKPISHRRACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVASPTSTYSSYEEPSDCDSYCKASKGKMKITMKKYCKKDYAVQVHVLKGDKAGEWWKFTVNIISVYKQGRHRIRRGDQL---------LWVRAKDVACRCPKIKPGRKYLLLGT--DDDSPGHSGVVADKGSLLIPWKDLWGRRLRKFQQRDKRGKC 601

[Close]

BLAST of Netrin 1 vs. Ensembl Medaka
Match: NTN1 (netrin-1 [Source:NCBI gene;Acc:101155405])

HSP 1 Score: 291.582 bits (745), Expect = 6.911e-90
Identity = 177/592 (29.90%), Postives = 290/592 (48.99%), Query Frame = 2

Query:   74 CYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSS-----CDFCQRKSK---RINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            CY  +G+P+ C P  +N A    ++ SSTCG+                       C++ DPK       + D +     TCW SE   +  YP +V LTL L K+  +++++++ C   P+ ++IYK       W P+Q+++  C+  +  P     T       N  + VC D    M    GG      LI F+   GR        +   Q+W+ AT+I++  + +    +G+    +   A +  Y +  SD+ +GG+  C+GHASR ++  D +  C+C+H+TAG +C++C     D+PW  AT R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R  + PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI        ++S+     C+   + SK   +IN K++C K+   +V+I   +  G+W +F   I  V+ + +   R     L        WV    V C C   + G  YL++ N + +    Q+ ++ ++  ++  W++TW  +  +F  ++K GKC +
Sbjct:   38 CYDEHGNPRRCIPDFVNAAFGKEVKVSSTCGKT----------------------CDASDPKKYHPPAYLTDLNNPHNLTCWQSENFIQ--YPQNVTLTLSLGKKFEVTYVSLQFCSPRPESMVIYKSMDNGKTWVPFQFYSTQCRKMYNKPNRAVITKQ-----NEQEAVCTDSHTDMYPLTGG------LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKV--VFSRLHTFGDENEDDSELARD-SYFYAVSDLQVGGRCKCNGHASRCVKDRDGSLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVSPPTTPASSTEEASDCESYCKASKGKLKINMKKYCKKDYAVQVHILKADKMGEWWKFTVNIISVYKQGESRIRRGDQFL--------WVRAKDVACKCPKIKPGKKYLLLGNDEVSP--SQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 580

[Close]

BLAST of Netrin 1 vs. Ensembl Medaka
Match: ntn2 (netrin-3 [Source:NCBI gene;Acc:101160359])

HSP 1 Score: 281.182 bits (718), Expect = 1.942e-85
Identity = 175/619 (28.27%), Postives = 296/619 (47.82%), Query Frame = 2

Query:   65 LQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMD--YGGDEKLFRLIPFNPRQGRSFGDVLSKNE--QNWLAATEIRISYILTPKEHYGNLLLREKRNA---ENPV--------YHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSS-----CD-FCQ--RKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVK-------------TTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNR 1813
            L  CY   G  + C P  IN A    +  SS CG   + S           + ++C+ C++ DP+ +  +  + D +     TCW SE ++ S  P +V LTL L K+  I++++++ C   P+ + IYK       W P+Q+++  C+  +  P   T T       N  + +C D    +    GG      LI F+   GR        +   Q+W+  T+IR+ +   P+     +L     N    ++PV        Y +   D  +GG+  C+GHASR ++  +    C+C+H+T G +C++C     D+PW  A  R    C  C CN H+ +C F+  ++  SGR  G  C++C  NT G  C  C  G++R    PI H+ ACK C CH VG+ +G  C+Q +G+C CK GVTG TC  CA GY+Q+ S   PC KI  +      +S+     C+ +C+  + + +IN K++C K+   +VN+   E+ G W +F   +  V+ +++ +P     N+       +WVH   + C C   +    +LVM   +             T+    +  L+ +++ ++  W++ W  +  +F  ++K GKC++
Sbjct:   34 LDPCYDETGTARRCIPEFINAAFGKEVMVSSVCGRPPSRSCSVVERGDERPSVRTCQICDAADPRRAHPASYLTDLNSAHNLTCWQSENLNTS--PHNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGKTWMPYQFYSSQCRRMYNKPNKATITKQ-----NEQEALCTDGHTDLYPLSGG------LIAFSTLDGRPSSKDFDNSPVLQDWVTVTDIRVVF-GRPQLSREFVLGAGSNNGGRDDDPVAVTSTLSTYFYAVGDFQVGGRCKCNGHASRCLKDKEGKLVCDCKHNTEGPECDRCKPFHYDRPWQRANAREANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGRPITHRRACKACDCHPVGA-AGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVVNPTAVVSSTEEPADCESYCKPVKGNLKINMKKYCKKDYAVQVNVLDMETVGDWAKFSVSLVSVY-KSRGEPLKRGDNI-------LWVHMKDLACKCPKIQMSKKFLVMGGSEGGTGPAAGPGVGATSPGAERVGLVADKNSLVIQWRDVWSRRLRKFQRKEKKGKCSK 629

[Close]

BLAST of Netrin 1 vs. Planmine SMEST
Match: SMESG000006779.1 (SMESG000006779.1)

HSP 1 Score: 404.06 bits (1037), Expect = 5.145e-133
Identity = 219/607 (36.08%), Postives = 333/607 (54.86%), Query Frame = 2

Query:   44 LVALNGELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGA-ESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTPKEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPA--VCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGT--SMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNRFTRQKRHVKRRN 1849
            L  + G   +C+S +G  K CEP  IN+AQ    E +STCG+ G+ + IC  W+   G     C KC+   P+LS++  +V D +I+G ET W+S  + + S   S+N+T+ L K   + +I VE  G  PD +++YK D     W PW YF+  C+ +FKM       +   S  N + P CF  + S+         +++PFNP  GR+     S+  + W++ T+I IS +LT           +KRN ++P  H   SDI IG +  C+GHA  +I+ +  T  C+C H TAG DC +C +  NDQPW       PA  +C+RC CNNH+ +C FD  ++  S   HGS C+ C  +T GP C+ C+PGY+R  A+PI H   C+ C CH  GSL  + C+  +G C CK GV GK C  C  GY+QT S   PC   +K  +L+ +   C  C +   RI F++FC K    K++I+S+E  G+W RF   + ++W R QQ  + SQ+NL  SE +   +WV    + C C + + GH+YL++  +K   ++ Q ELI+++     DW + W  +   F  +++ GKC+R+  +++H K  N
Sbjct:   17 LTIIKG-FSSCFSESGRAKFCEPDFINVAQNATFEVTSTCGQKGSTDRICRNWYTSSGLNEGKCLKCDDRIPELSRNISLVFDRNIQGHETVWVSGRIPKFSGIHSINITINLNKLYEVYYIIVEFAGQLPDSMVLYKRDKNGKTWLPWNYFSSSCKKSFKMKRSKPLHIQQRS-FNKISPACFSFKHSVQNITSN--IKVLPFNPMTGRTSLLPNSRLIKEWVSVTDIMIS-LLTDGS--------KKRN-KSPYDHLSISDITIGARSQCYGHAKSLIKKNGTTV-CDCLHKTAGPDCSQCLKTHNDQPWKIIFPSEPAGNICERCFCNNHAEECKFDEKIYKNSSGKHGSRCLHCLHHTTGPHCNSCSPGYYRNRAFPINHPQVCQKCGCHPYGSLPQSYCNPDNGICQCKIGVEGKLCNRCKKGYQQTKSSSTPCAPETK-NNLMATEERCGSCGKNRPRIRFRKFCKKHIMIKISIQSKEIHGEWTRFGVRVLKIW-RIQQSLK-SQVNLYESEYSIYPIWVENADIRCKCPNLQLGHTYLLLTKIKLKNYLNQPELIVDRKSSALDWSDDWIRRLDMFKMREEQGKCDRYQYKRKHSKLMN 605

[Close]

BLAST of Netrin 1 vs. Planmine SMEST
Match: SMESG000050895.1 (SMESG000050895.1)

HSP 1 Score: 395.201 bits (1014), Expect = 1.364e-128
Identity = 206/616 (33.44%), Postives = 329/616 (53.41%), Query Frame = 2

Query:   47 VALNGELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKL-GKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDL---EKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYI-LTPKE----------HYGNLLLREKRNAEN----PVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNRFTRQKRHV 1837
            V    +   CY  NG P+ C P   N+ + +  E +STCG NG E IC  W+DK   +A + C  C++       S   + D HI   +TCW S  + E+     VN+T+ LKK   + +I +++CG  PD I IYK       W PWQ+F++DC   FKMP  T +  +  +  N  + +C +L   E+  DYG  E +   +PF+   GR  G   S++   W+  T++RIS +  TP++          ++   L +   N  N    P+ HFG SD+ +GG+  C+GHA+R +   +D  +C+C H+T G++CE+C   + D+PW  AT +N  VCK C+C NHS KC+F   ++ ++   HG  C++C  NT G  CD+CA  ++R    P+ H  AC  C CH++GS+    CD+ +G+C+C+ GVTG+TC  C  GYKQ+NS   PC   S +  +  ++  C  C  K KRI FK+FC +++ F+    S+E  G  IR+  +I+++W  ++           +      W++ + V C C   E G SYL++   K   ++   EL ++   V+  W  +WE +  +F  ++K GKC ++ ++K  +
Sbjct:   21 VIFESQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSH--ITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPT-TNEQNSQITPANIHEVLCVELKAPERYNDYGQAETV---LPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYFKKKMKI 629

[Close]

BLAST of Netrin 1 vs. Planmine SMEST
Match: SMESG000050895.1 (SMESG000050895.1)

HSP 1 Score: 393.66 bits (1010), Expect = 5.483e-128
Identity = 204/616 (33.12%), Postives = 329/616 (53.41%), Query Frame = 2

Query:   47 VALNGELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKL-GKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDL---EKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYI-LTPKE----------HYGNLLLREKRNAEN----PVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNRFTRQKRHV 1837
            V    +   CY  NG P+ C P   N+ + +  E +STCG NG E IC  W+DK   +A + C  C++       S   + D HI   +TCW S  + E+     VN+T+ LKK   + +I +++CG  PD I IYK       W PWQ+F++DC   FKMP  T +  +  +  N  + +C +L   E+  DYG  E +   +PF+   GR  G   S++   W+  T++RIS +  TP++          ++   L +   N  N    P+ HFG SD+ +GG+  C+GHA+R +   +D  +C+C H+T G++CE+C   + D+PW  AT +N  VCK C+CN HS +C F+  +++++   +G  CI+C  +T G  C+ C  G+FR    P  H+ AC  C CH++GS+    CD+ +G+C+C+ GVTG+TC  C  GYKQ+NS   PC   S +  +  ++  C  C  K KRI FK+FC +++ F+    S+E  G  IR+  +I+++W  ++           +      W++ + V C C   E G SYL++   K   ++   EL ++   V+  W  +WE +  +F  ++K GKC ++ ++K  +
Sbjct:   21 VIFESQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSH--ITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPT-TNEQNSQITPANIHEVLCVELKAPERYNDYGQAETV---LPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYFKKKMKI 629

[Close]

BLAST of Netrin 1 vs. Planmine SMEST
Match: SMESG000076695.1 (SMESG000076695.1)

HSP 1 Score: 362.459 bits (929), Expect = 5.598e-116
Identity = 209/659 (31.71%), Postives = 319/659 (48.41%), Query Frame = 2

Query:   41 GLVALNGELQTCYSANGDPKPCEPLLINLAQPMHIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYI-----LTPKEHYGNLLLREKRNAENPV--------------YHFGSSDIMIGGQPLCHGHASRIIRTSDDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKI---------------SKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVWTRNQQDPRVSQLNLESSE---GTSMWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNRFTRQKRHVK----------RRNFASTYNQYA 1876
             +  L    QT    +G    C P  IN+AQ   I  +S+CGE   + IC  W        + C  C++       S K + D   +   TCW S  V+       VN+++  KK   + ++ ++ C   PD I IYK       W PWQY++K+CQ  F +P      +    +  SL P CFDL +    G   +   ++PF+   GR   D L K    W+  T++RI+       ++    YG   L + R   + +               ++G SD+ +GG+  C+GH+++ I  +D    C+C+H+T G DC+KC E F+D  W  A+  NP  CKRC+CN HS  C F+ NV++K+G+  G  C  C  NT G QC  C  GY+R    P+ H  ACK C CH+VGS +   CD+  G+CFCK GV G+ C  C  GY QT S+  PC K                SK   +  + S C  C  K KRI FK+FC +++ F   I+S+E  G+ +RF  +I++VW   +   ++SQ   E S+      +W+  + V C C +   G SYL++   K      + EL+L+   V+  W+ +WE +  +F T+    KC +F ++K  +K          +R+F  T N ++
Sbjct:   21 AISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRDCSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEY-SLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRKMNDTLIK----WITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEKRKRIRFKKFCRRDSVFMGVIESKEVHGKMVRFELQIKEVW---RVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFLQKKSKIKHNRINRVGKNKRSFLLTKNPFS 671

[Close]

BLAST of Netrin 1 vs. Planmine SMEST
Match: SMESG000006806.1 (SMESG000006806.1)

HSP 1 Score: 300.442 bits (768), Expect = 1.962e-92
Identity = 202/660 (30.61%), Postives = 310/660 (46.97%), Query Frame = 2

Query:   59 GELQTCYSANGDPKPCEPLLINLAQPM-HIEASSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIRGKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGH-NPDGIIIYKMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLEKSMDYGGDEKLFRLI------PFNPRQGRSFGDVLSKNEQNWLAATEIRIS---------------YILTP-----------KEHYGNLL-----LREKRNAENPVYH----FGSSDIMIGGQPLCHGHASRIIRTS-DDTYQCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVFDFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACKPCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPCRKISKLRHLVKSNS---SCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQWIRFISEIEQVW-------TRNQQDPRVSQLNLESSEGTS----MWVHKDLVDCGCVDFEFGHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMGKCNRFTRQKRHVKRRNFASTY 1864
            G    CYS  G    C P   N+ + M   E +STCG+N  + IC +        H +C  C     K + S   + D H+    T W S+ V+      +VN+T    K   I +I++ L     PD III K       W+ W YF+KDC  +F +  +     N +SD + +     D   +     D KL  L+       F       F    S    +W++AT IRI+               +   P           K +Y ++L     L++K+     V      F  +DI IGG+  C+GHA R ++   D+TY C+CQH+TAGKDCE C E F D+ WS AT+ + A CKRC CN HS KC F+  +++ S +  G  C+ C  NT G  C QC  GY R  + P+ H + C  C CH +GS+    CDQ + +C CK GV G +C  C  G++QT S   PC  +  L  +  + +    C  C  K KRI FK++C K+    V ++SRE  G+  RF  ++  V+       T    D   S   + S++       MW+ +  + C C   + G +YLV+  +   +++ ++EL+L+Q  V   W++TWE +  +F  ++  G C ++  ++R+ +R+     Y
Sbjct:   30 GSNSLCYSE-GKAFRCVPPFTNIIENMIPDEITSTCGQNKKQRICVD--------HINCHSC----MKDTHSINYLTDQHLNNNITFWASDFVNHGD---NVNITFSFGKLFEIYYISLVLIPLLEPDSIIISKSIDNGTSWTEWHYFSKDCYRSFGIQPMD---FNHYSD-SKITESTVDQSLTCTSIPDSKLGNLVNSPSVLAFTTNNPNFFSHA-SDQYNSWMSATNIRITLRKSETNFLNSHLDGFTYPPHLKQYFNRIYRKNNYSSILPVNRKLKQKKRNSPSVLKISDFFALADISIGGRCQCYGHAGRCLKNPVDNTYHCDCQHNTAGKDCEMCREGFVDKRWSVATVNSAAECKRCNCNLHSKKCEFNEKLYIVSNKQSGGVCVGCEHNTDGRYCHQCNKGYHRDWSKPLSHHHVCIKCRCHPIGSIYPDVCDQRNSQCTCKTGVGGLSCNRCQKGFQQTKSPITPCVDVIDLHKIPMAQAPENRCQHCNNKRKRIRFKKYCRKDAVLLVTMQSREQHGEMARFEMKVNYVYRIDTSKFTEMHPDFLASMNGIMSNQFIHSTFPMWIKETDLKCKCPSLQLGMTYLVILKLHAIKYLERSELLLDQKSVALPWQKTWERRMKKFSNKEHQGLCEKWKLKRRYYRRQKHTKNY 668

The following BLAST results are available for this feature:

BLAST of Netrin 1 vs. Ensembl Human
BLAST of Netrin 1 vs. Ensembl Celegans
BLAST of Netrin 1 vs. Ensembl Fly
BLAST of Netrin 1 vs. Ensembl Zebrafish
BLAST of Netrin 1 vs. Ensembl Xenopus
BLAST of Netrin 1 vs. Ensembl Mouse
BLAST of Netrin 1 vs. UniProt/SwissProt
BLAST of Netrin 1 vs. TrEMBL
BLAST of Netrin 1 vs. Ensembl Cavefish
BLAST of Netrin 1 vs. Ensembl Sea Lamprey
BLAST of Netrin 1 vs. Ensembl Yeast
BLAST of Netrin 1 vs. Ensembl Nematostella
BLAST of Netrin 1 vs. Ensembl Medaka
BLAST of Netrin 1 vs. Planmine SMEST

BLAST of Netrin 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NTN1	2.966e-93	30.53	netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]	[more]
NTN3	8.392e-75	28.20	netrin 3 [Source:HGNC Symbol;Acc:HGNC:8030]	[more]
LAMC1	4.038e-57	32.18	laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HG...	[more]
LAMC3	3.601e-53	31.25	laminin subunit gamma 3 [Source:HGNC Symbol;Acc:HG...	[more]
NTN5	3.293e-50	30.61	netrin 5 [Source:HGNC Symbol;Acc:HGNC:25208]	[more]

BLAST of Netrin 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
unc-6	9.285e-97	31.77	Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34...	[more]
unc-6	9.285e-97	31.77	Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34...	[more]
lam-2	4.593e-57	31.83	Laminin-like protein lam-2 [Source:UniProtKB/Swis...	[more]
lam-3	1.849e-42	27.04	LAMinin related. See also lmb; Laminin alpha chain...	[more]
lam-1	1.841e-36	27.48	LAMinin related. See also lmb [Source:UniProtKB/T...	[more]

BLAST of Netrin 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NetA	3.881e-71	28.99	gene:FBgn0015773 transcript:FBtr0073942	[more]
NetA	3.881e-71	28.99	gene:FBgn0015773 transcript:FBtr0346088	[more]
NetA	1.465e-70	32.83	gene:FBgn0015773 transcript:FBtr0308337	[more]
LanB2	1.205e-54	33.26	gene:FBgn0267348 transcript:FBtr0345031	[more]
LanB2	1.205e-54	33.26	gene:FBgn0267348 transcript:FBtr0076382	[more]

BLAST of Netrin 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ntn1a	3.405e-97	31.37	netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169]	[more]
ntn1a	3.405e-97	31.37	netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169]	[more]
ntn2	1.731e-91	29.55	netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2]	[more]
ntn2	1.761e-91	29.55	netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2]	[more]
ntn1b	8.704e-90	29.90	netrin 1b [Source:ZFIN;Acc:ZDB-GENE-990415-168]	[more]

BLAST of Netrin 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ntn1	8.215e-89	30.42	netrin 1 [Source:NCBI gene;Acc:779839]	[more]
rps16	3.177e-84	29.85	ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-...	[more]
rps16	1.029e-78	28.96	ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-...	[more]
utp4	2.521e-56	31.67	UTP4 small subunit processome component [Source:Xe...	[more]
utp4	2.767e-56	31.67	UTP4 small subunit processome component [Source:Xe...	[more]

BLAST of Netrin 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ntn1	3.380e-93	30.36	netrin 1 [Source:MGI Symbol;Acc:MGI:105088]	[more]
Ntn1	3.380e-93	30.36	netrin 1 [Source:MGI Symbol;Acc:MGI:105088]	[more]
Ntn3	1.554e-75	27.69	netrin 3 [Source:MGI Symbol;Acc:MGI:1341188]	[more]
Lamc1	1.725e-57	31.89	laminin, gamma 1 [Source:MGI Symbol;Acc:MGI:99914]	[more]
Lamc3	1.525e-55	32.27	laminin gamma 3 [Source:MGI Symbol;Acc:MGI:1344394...	[more]

BLAST of Netrin 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P34710\|UNC6_CAEEL	1.181e-95	31.77	Netrin unc-6 OS=Caenorhabditis elegans OX=6239 GN=...	[more]
sp\|O95631\|NET1_HUMAN	1.424e-92	30.53	Netrin-1 OS=Homo sapiens OX=9606 GN=NTN1 PE=1 SV=2	[more]
sp\|O09118\|NET1_MOUSE	2.364e-92	30.36	Netrin-1 OS=Mus musculus OX=10090 GN=Ntn1 PE=1 SV=...	[more]
sp\|Q90922\|NET1_CHICK	2.672e-91	30.52	Netrin-1 OS=Gallus gallus OX=9031 GN=NTN1 PE=1 SV=...	[more]
sp\|Q2HXW4\|NET1_PIG	4.901e-91	30.50	Netrin-1 OS=Sus scrofa OX=9823 GN=NTN1 PE=2 SV=1	[more]

BLAST of Netrin 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0K0EM36	8.081e-98	31.46	Uncharacterized protein OS=Strongyloides stercoral...	[more]
A0A090LSV4	8.343e-98	31.80	Netrin-1a OS=Strongyloides ratti OX=34506 GN=SRAE_...	[more]
A0A5K3F5Z3	1.610e-97	29.21	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
V4AN98	3.770e-97	31.52	Uncharacterized protein OS=Lottia gigantea OX=2251...	[more]
A0A0N5C6U6	3.993e-97	31.86	Uncharacterized protein OS=Strongyloides papillosu...	[more]

BLAST of Netrin 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NTN1	2.949e-93	30.74	netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]	[more]
ntn1b	9.912e-92	30.74	netrin-1-like [Source:NCBI gene;Acc:111191060]	[more]
NTN1	1.323e-91	30.74	netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]	[more]
NTN1	3.340e-68	26.37	netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]	[more]
ntn1b	1.245e-67	27.05	netrin-1-like [Source:NCBI gene;Acc:111191060]	[more]

BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000009682.1	8.950e-43	31.17	pep scaffold:Pmarinus_7.0:GL479835:738:11671:-1 ge...	[more]
ENSPMAT00000004606.1	1.969e-24	28.91	pep scaffold:Pmarinus_7.0:GL477874:5526:15188:-1 g...	[more]
ENSPMAT00000004614.1	7.790e-24	30.14	pep scaffold:Pmarinus_7.0:GL477874:5547:15173:-1 g...	[more]
ENSPMAT00000008925.1	3.666e-23	25.43	pep scaffold:Pmarinus_7.0:GL476496:30277:70426:-1 ...	[more]
ENSPMAT00000007784.1	1.172e-19	25.25	pep scaffold:Pmarinus_7.0:GL477336:382472:417638:1...	[more]

BLAST of Netrin 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Netrin 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO36836	2.540e-69	27.95	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36523	3.197e-51	27.81	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39502	1.614e-43	28.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46759	2.933e-30	28.23	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36500	3.996e-30	26.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Netrin 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NTN1	5.166e-94	30.24	netrin-1 [Source:NCBI gene;Acc:101155405]	[more]
ntn1b	2.745e-91	31.13	netrin-1 [Source:NCBI gene;Acc:101161061]	[more]
ntn1b	3.298e-91	31.13	netrin-1 [Source:NCBI gene;Acc:101161061]	[more]
NTN1	6.911e-90	29.90	netrin-1 [Source:NCBI gene;Acc:101155405]	[more]
ntn2	1.942e-85	28.27	netrin-3 [Source:NCBI gene;Acc:101160359]	[more]

BLAST of Netrin 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000006779.1	5.145e-133	36.08	SMESG000006779.1	[more]
SMESG000050895.1	1.364e-128	33.44	SMESG000050895.1	[more]
SMESG000050895.1	5.483e-128	33.12	SMESG000050895.1	[more]
SMESG000076695.1	5.598e-116	31.71	SMESG000076695.1	[more]
SMESG000006806.1	1.962e-92	30.61	SMESG000006806.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30023593 ID=SMED30023593|Name=Netrin 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1962bp
GATCTTGAAATTCTTTTTAAAATTTCTAATCTTATTCATTGGTCTTGTGG
CCTTAAATGGAGAACTGCAGACCTGCTACAGTGCCAATGGAGATCCTAAA
CCTTGTGAACCATTATTAATAAATTTGGCTCAGCCAATGCATATTGAAGC
TAGCTCTACGTGTGGAGAAAACGGAGCGGAAAGTATTTGTACAGAATGGT
TTGACAAACTAGGAAAAGCTCATAAGTCCTGTGAGAAATGCAATTCTTTA
GATCCTAAATTATCAAAATCGTCAAAAATGGTGGTTGATTCACATATACG
AGGCAAGGAGACTTGTTGGATTTCAGAAGGTGTTCATGAAAGTAGTTATC
CAACTAGCGTTAATCTTACATTGGGTTTGAAAAAGAGGTCATTAATATCA
TTTATTACTGTGGAATTATGTGGTCACAACCCGGATGGCATTATTATTTA
TAAAATGGACAGTGAAACAGATGATTGGTCTCCTTGGCAATATTTTGCTA
AAGACTGTCAACTGACATTTAAGATGCCGGCTTTAACAACGGATACAGTT
AATACTTTTTCCGATATAAATTCATTGAAACCAGTTTGTTTTGATTTGGA
AAAAAGTATGGACTATGGAGGAGATGAAAAACTATTCAGACTTATCCCAT
TCAATCCAAGACAAGGCAGAAGTTTTGGAGATGTATTATCTAAAAATGAA
CAAAACTGGTTGGCAGCTACAGAAATACGAATCAGTTATATTCTAACTCC
TAAAGAACATTACGGAAATCTGCTGTTGAGAGAAAAGCGAAATGCAGAAA
ATCCTGTTTATCATTTTGGTTCATCTGATATAATGATTGGTGGGCAACCT
TTATGTCATGGACATGCTTCGAGAATAATCAGAACTTCGGATGATACTTA
TCAGTGTGAATGTCAGCACAGTACTGCTGGAAAGGATTGTGAAAAATGCC
ATGAAGAATTCAATGATCAACCGTGGAGTTCAGCAACGATTCGAAACCCA
GCGGTTTGTAAAAGATGCGAGTGTAACAATCATTCGATAAAATGTGTATT
CGATTTTAATGTTTTCCTGAAATCTGGTAGAATTCATGGCAGTTCTTGCA
TAGATTGTGGTGATAACACTGTCGGCCCTCAGTGTGATCAATGCGCTCCC
GGATATTTCCGGCAACATGCTTATCCTATTTACCATAAAAATGCTTGTAA
ACCTTGCTTATGTCATTCAGTTGGATCTCTTTCGGGTACACCCTGCGATC
AAGTAAGTGGGAAATGTTTCTGTAAGCCTGGAGTGACTGGGAAAACATGT
ACCCATTGTGCACCGGGTTATAAACAAACAAATTCCCTAAAGAATCCTTG
CAGAAAGATATCAAAATTGCGTCATTTAGTGAAATCAAATTCGAGTTGCG
ATTTTTGTCAAAGGAAAAGTAAAAGAATTAATTTTAAGAGATTTTGCAGC
AAGGAAACAAATTTCAAAGTAAATATCAAGAGTAGAGAATCAAGGGGTCA
GTGGATTCGGTTCATTTCTGAAATCGAACAGGTCTGGACAAGAAATCAAC
AAGATCCCCGAGTATCCCAACTTAATCTAGAATCTAGTGAAGGGACTTCG
ATGTGGGTTCATAAAGATCTCGTGGACTGCGGTTGCGTTGATTTTGAATT
CGGTCATTCATATTTAGTCATGGCCAATGTGAAAACAACGGAATTTATGG
GCCAAACTGAACTTATTTTAAACCAAAGTGATGTAATTGAGGATTGGAAG
GAGACATGGGAGGAGCAATTTTCTCAGTTTTATACCCAGGATAAAATGGG
AAAATGCAATCGGTTTACTCGACAAAAGCGACACGTCAAGAGGCGTAATT
TTGCCTCAACCTATAACCAATATGCTATCTATTCCTGATCATTTGGACCC
GGGATTAATTTAATTAACATTTTATCTAGCAGCTGAATGTGATGTCTTAT
TGTATTTATAAA

protein sequence of SMED30023593-orf-1

>SMED30023593-orf-1 ID=SMED30023593-orf-1|Name=SMED30023593-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=629bp
ILKFFLKFLILFIGLVALNGELQTCYSANGDPKPCEPLLINLAQPMHIEA
SSTCGENGAESICTEWFDKLGKAHKSCEKCNSLDPKLSKSSKMVVDSHIR
GKETCWISEGVHESSYPTSVNLTLGLKKRSLISFITVELCGHNPDGIIIY
KMDSETDDWSPWQYFAKDCQLTFKMPALTTDTVNTFSDINSLKPVCFDLE
KSMDYGGDEKLFRLIPFNPRQGRSFGDVLSKNEQNWLAATEIRISYILTP
KEHYGNLLLREKRNAENPVYHFGSSDIMIGGQPLCHGHASRIIRTSDDTY
QCECQHSTAGKDCEKCHEEFNDQPWSSATIRNPAVCKRCECNNHSIKCVF
DFNVFLKSGRIHGSSCIDCGDNTVGPQCDQCAPGYFRQHAYPIYHKNACK
PCLCHSVGSLSGTPCDQVSGKCFCKPGVTGKTCTHCAPGYKQTNSLKNPC
RKISKLRHLVKSNSSCDFCQRKSKRINFKRFCSKETNFKVNIKSRESRGQ
WIRFISEIEQVWTRNQQDPRVSQLNLESSEGTSMWVHKDLVDCGCVDFEF
GHSYLVMANVKTTEFMGQTELILNQSDVIEDWKETWEEQFSQFYTQDKMG
KCNRFTRQKRHVKRRNFASTYNQYAIYS*

Aliases

The feature 'Netrin 1' has the following synonyms


Synonym
netrin-like

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000023	embryonic pharynx
PLANA:0000058	embryonic digestive system

Vocabulary: **INTERPRO**
Term	Definition
IPR038684	Laminin_N_sf
IPR002049	Laminin_EGF
IPR008211	Laminin_N
IPR018933	Netrin_module_non-TIMP
IPR013032	EGF-like_CS
IPR001134	Netrin_domain
IPR008993	TIMP-like_OB-fold

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

Vocabulary: **cellular component**
Term	Definition
GO:0005576	extracellular region

Vocabulary: **Schmidtea mediterranea Developmental Stages**
Term	Definition
PLANA:0000004	Stage 4
PLANA:0000002	Stage 2
PLANA:0000003	Stage 3

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002049	Laminin EGF domain	SMART	SM00180	lamegf_3	coord: 278..334 e-value: 1.7 score: 8.5 coord: 400..448 e-value: 1.8E-8 score: 44.1 coord: 337..397 e-value: 4.7E-6 score: 36.1
IPR002049	Laminin EGF domain	PFAM	PF00053	Laminin_EGF	coord: 400..443 e-value: 2.0E-8 score: 34.2 coord: 283..325 e-value: 3.7E-6 score: 27.0 coord: 337..388 e-value: 3.0E-6 score: 27.3
IPR002049	Laminin EGF domain	PROSITE	PS01248	EGF_LAM_1	coord: 420..448
IPR002049	Laminin EGF domain	PROSITE	PS01248	EGF_LAM_1	coord: 364..400
IPR002049	Laminin EGF domain	PROSITE	PS50027	EGF_LAM_2	coord: 400..450 score: 17.415
IPR002049	Laminin EGF domain	PROSITE	PS50027	EGF_LAM_2	coord: 337..399 score: 11.321
IPR008211	Laminin, N-terminal	SMART	SM00136	LamNT_2	coord: 27..279 e-value: 2.8E-14 score: 33.4
IPR008211	Laminin, N-terminal	PFAM	PF00055	Laminin_N	coord: 33..279 e-value: 7.4E-35 score: 120.6
IPR008211	Laminin, N-terminal	PROSITE	PS51117	LAMININ_NTER	coord: 29..280 score: 26.307
IPR038684	Laminin, N-terminal domain superfamily	GENE3D	G3DSA:2.60.120.1490		coord: 12..302 e-value: 1.2E-49 score: 171.1
IPR008993	Tissue inhibitor of metalloproteinases-like, OB-fold	GENE3D	G3DSA:2.40.50.120		coord: 459..602 e-value: 8.6E-10 score: 40.5
IPR008993	Tissue inhibitor of metalloproteinases-like, OB-fold	SUPERFAMILY	SSF50242	TIMP-like	coord: 461..597
None	No IPR available	GENE3D	G3DSA:2.10.25.10		coord: 303..402 e-value: 1.4E-25 score: 91.4
None	No IPR available	GENE3D	G3DSA:2.10.25.10		coord: 403..450 e-value: 7.2E-11 score: 43.8
None	No IPR available	PANTHER	PTHR10574:SF292	NETRIN-3	coord: 17..601
None	No IPR available	PANTHER	PTHR10574	NETRIN/LAMININ-RELATED	coord: 17..601
None	No IPR available	CDD	cd00055	EGF_Lam	coord: 399..449 e-value: 1.13988E-11 score: 57.7494
None	No IPR available	CDD	cd00055	EGF_Lam	coord: 283..323 e-value: 8.94551E-6 score: 41.1858
None	No IPR available	CDD	cd00055	EGF_Lam	coord: 336..385 e-value: 0.00142557 score: 35.0226
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..18 score: 0.778
None	No IPR available	SUPERFAMILY	SSF57196	EGF/Laminin	coord: 283..339
None	No IPR available	SUPERFAMILY	SSF57196	EGF/Laminin	coord: 400..443
None	No IPR available	SUPERFAMILY	SSF57196	EGF/Laminin	coord: 337..402
IPR018933	Netrin module, non-TIMP type	PFAM	PF01759	NTR	coord: 477..591 e-value: 1.1E-10 score: 41.3
IPR013032	EGF-like, conserved site	PROSITE	PS00022	EGF_1	coord: 300..311
IPR001134	Netrin domain	PROSITE	PS50189	NTR	coord: 464..600 score: 15.354

Main menu

Netrin 1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

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