Glucose-6-phosphatase

Overview
NameGlucose-6-phosphatase
Smed IDSMED30023565
Length (bp)1291
Neoblast Clusters

Zeng et. al., 2018




 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30023565

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30023565h1SMcG0014689 dd_Smed_v4_101944_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30023565h1SMcG0014689 dd_Smed_v4_101944_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30023565h1SMcG0014689 dd_Smed_v4_101944_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30023565h1SMcG0014689 dd_Smed_v4_101944_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30023565h1SMcG0014689 dd_Smed_v4_101944_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023565h1SMcG0014689 dd_Smed_v4_101944_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
anterior sideSMED30023565h1SMcG0014689 dd_Smed_v4_101944_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30023565h1SMcG0014689 Contig44807newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30023565h1SMcG0014689 Contig44807uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Glucose-6-phosphatase vs. Ensembl Human
Match: G6PC3 (glucose-6-phosphatase catalytic subunit 3 [Source:HGNC Symbol;Acc:HGNC:24861])

HSP 1 Score: 129.413 bits (324), Expect = 3.344e-33
Identity = 87/295 (29.49%), Postives = 143/295 (48.47%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVL-----FKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVA-STKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDW--TNQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSII 1003
            L A + I E +Q Q   + +    I+ + DP + F F FP  YY+   +G+ +LW     + L ++ K     DRP+WWV ++    + P   + Q+P +C   PG PSGHC++T A  W I+  L      + +++  ++  +L Y  F++ V +SRIF+ A+FPHQ + G+  G VLG  +     +    S Y L A A  +  S +Y  L   LG+ + W+   A K C   +W   +  PF  +    R +G   G GI+L      Q R   L   +   C+ + + ++
Sbjct:    5 LGAGIVIAEALQNQLAWLENVWLWITFLGDPKILFLFYFPAAYYASRRVGIAVLWISLITEWLNLIFKWFLFGDRPFWWVHESGYYSQAP-AQVHQFPSSCETGPGSPSGHCMITGAALWPIMTALSSQVATRARSRWVRVMPSLAYCTFLLAVGLSRIFILAHFPHQVLAGLITGAVLGWLMTPRVPMERELSFYGLTALALMLGTSLIYWTLF-TLGLDLSWSISLAFKWCERPEWIHVDSRPFASL---SRDSGAALGLGIALHSPCYAQVRRAQLGNGQKIACLVLAMGLL 294          
BLAST of Glucose-6-phosphatase vs. Ensembl Human
Match: G6PC (glucose-6-phosphatase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4056])

HSP 1 Score: 112.079 bits (279), Expect = 7.555e-27
Identity = 85/306 (27.78%), Postives = 143/306 (46.73%), Query Frame = 2
Query:  179 IQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVS---IAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFK---------WKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGN--------YVASTKLYNSPSVY-YLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCV 1027
            +Q  Y+        +S+I+D   AF  +FPI ++    +G+ +LW     D L +V K      RPYWWV  +     + S   I Q+P+TC   PG PSGH + T+ VY+ ++              ++ +C  + L L +    + V +SRI+LAA+FPHQ + GV  GI +          Y AS K Y   + + + +A  F ++L G        LG+ + WT   A + C   +W   +  PF  +    ++ G L G G++L  +   +     L++    R  S++ S++L+  F  +
Sbjct:   19 LQVNYQDSQDWFILVSVIADLRNAFYVLFPIWFHLQEAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWV-LDTDYYSNTSVPLIKQFPVTCETGPGSPSGHAMGTAGVYYVMVTSTLSIFQGKIKPTYRFRCLNVILWLGFWAVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVAETFSHIHSIYNASLKKYFLITFFLFSFAIGFYLLLKG--------LGVDLLWTLEKAQRWCEQPEWVHIDTTPFASL---LKNLGTLFGLGLALNSSMYRESCKGKLSKWLPFRLSSIVASLVLLHVFDSL 312          
BLAST of Glucose-6-phosphatase vs. Ensembl Human
Match: G6PC2 (glucose-6-phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:28906])

HSP 1 Score: 110.923 bits (276), Expect = 1.815e-26
Identity = 78/267 (29.21%), Postives = 128/267 (47.94%), Query Frame = 2
Query:  167 IIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVS---IAQYPLTCAILPGGPSGHCLVTSAVYWAIL-AVLFKWKNKCEKMSLTL----------IYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSV-YYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDW--TNQNPFQDIFPFFRSAGVLAGTGISL 916
            II+ +Q  Y+   + L  +S + DP   F   FP+ +     +G  ++W     D L ++ K      RPYWWV +     P+ S   + Q+P TC   PG PSGH +  S V++ ++ A L       +K S+TL          ++ +  I V +SR+F+A +FPHQ I+GV  G+++      T    + S+  YL  + F  + +  +  L  +L I + W+   A K C + DW   +  PF  +    R+ GVL G G ++
Sbjct:   11 IIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWVAVIGDWLNLIFKWILFGHRPYWWV-QETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGASCVWYVMVTAALSHTVCGMDKFSITLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGIQTASLGTYLKTNLFLFLFAVGFYLLLRVLNIDLLWSVPIAKKWCANPDWIHIDTTPFAGL---VRNLGVLFGLGFAI 273          
BLAST of Glucose-6-phosphatase vs. Ensembl Human
Match: G6PC2 (glucose-6-phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:28906])

HSP 1 Score: 110.923 bits (276), Expect = 1.815e-26
Identity = 78/267 (29.21%), Postives = 128/267 (47.94%), Query Frame = 2
Query:  167 IIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVS---IAQYPLTCAILPGGPSGHCLVTSAVYWAIL-AVLFKWKNKCEKMSLTL----------IYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSV-YYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDW--TNQNPFQDIFPFFRSAGVLAGTGISL 916
            II+ +Q  Y+   + L  +S + DP   F   FP+ +     +G  ++W     D L ++ K      RPYWWV +     P+ S   + Q+P TC   PG PSGH +  S V++ ++ A L       +K S+TL          ++ +  I V +SR+F+A +FPHQ I+GV  G+++      T    + S+  YL  + F  + +  +  L  +L I + W+   A K C + DW   +  PF  +    R+ GVL G G ++
Sbjct:   11 IIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWVAVIGDWLNLIFKWILFGHRPYWWV-QETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGASCVWYVMVTAALSHTVCGMDKFSITLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGIQTASLGTYLKTNLFLFLFAVGFYLLLRVLNIDLLWSVPIAKKWCANPDWIHIDTTPFAGL---VRNLGVLFGLGFAI 273          
BLAST of Glucose-6-phosphatase vs. Ensembl Human
Match: G6PC3 (glucose-6-phosphatase catalytic subunit 3 [Source:HGNC Symbol;Acc:HGNC:24861])

HSP 1 Score: 88.9669 bits (219), Expect = 1.250e-19
Identity = 72/259 (27.80%), Postives = 115/259 (44.40%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVA-STKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDW--TNQNPFQDIFPFFRSAGVLAGTGISL 916
            L A + I E +Q Q   + +    I+ + DP + F F FP  YY+   +G+ +LW     + L ++ K     DRP+WWV ++         +Q P   A            T A            +++  ++  +L Y  F++ V +SRIF+ A+FPHQ + G+  G VLG  +     +    S Y L A A  +  S +Y  L   LG+ + W+   A K C   +W   +  PF  +    R +G   G GI+L
Sbjct:    5 LGAGIVIAEALQNQLAWLENVWLWITFLGDPKILFLFYFPAAYYASRRVGIAVLWISLITEWLNLIFKWFLFGDRPFWWVHESG------YYSQAPAQVA------------TRA------------RSRWVRVMPSLAYCTFLLAVGLSRIFILAHFPHQVLAGLITGAVLGWLMTPRVPMERELSFYGLTALALMLGTSLIYWTLFT-LGLDLSWSISLAFKWCERPEWIHVDSRPFASL---SRDSGAALGLGIAL 229          
BLAST of Glucose-6-phosphatase vs. Ensembl Fly
Match: G6P (gene:FBgn0031463 transcript:FBtr0113017)

HSP 1 Score: 54.6842 bits (130), Expect = 7.868e-8
Identity = 69/272 (25.37%), Postives = 115/272 (42.28%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN-----VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFK---WK-------NKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGI-VLGNYVASTK-LYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQNPFQDIFPFFRSAGVLAGTGIS 913
            LT E+ I E  Q +          +S+  +P   F  + P+       I + +    T    L    K  + E RP W++ +      V K P V++  + L+C +  G P  H + T  V+  ILA  F    W        + C  +   LI G+ ++ + +SR++LA  F HQ I+G + GI  L  +  + K L++ P  Y + A  F   L+    ++   L I   W+   A K C +  +  ++    IF   R  G L G  ++
Sbjct:   16 LTRELFINEWAQERLSFGRPLWHFLSVHLEPNKMFNIIIPLCGIFSQEILVHLFTAFTLISTLNSFEKWIYPETRPLWFLREQFANNVVVKKPAVALESHQLSCEMTGGLPCAHSM-TFTVFVLILASFFFVHCWDRFAALRSSFCRCIMYLLIIGM-VVCMWLSRLYLATEFLHQCILGSYLGIRSLCTFEGNVKYLFSRPRRYAVSAVFFLGGLALSVYYVKLELNIDPHWSVREAFKWCPEPTYL-RHEVGPIFALVRDLGNLMGLALA 284          
BLAST of Glucose-6-phosphatase vs. Ensembl Zebrafish
Match: g6pc3 (glucose 6 phosphatase, catalytic, 3 [Source:NCBI gene;Acc:790919])

HSP 1 Score: 134.806 bits (338), Expect = 1.624e-35
Identity = 83/262 (31.68%), Postives = 134/262 (51.15%), Query Frame = 2
Query:  167 IIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN---VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWK-----NKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLL---GIQIKWTFCAADKHCYDTDWTNQN--PFQDIFPFFRSAGVLAGTGIS 913
            + E +Q + + +       S + DP  A   VFP+ +Y     G+ +LW    ++ L +VLK     +RPYWW+G++     K P+V   Q+  TC   PG PSGH +VTSAV+W I++ L  +      +K     L L+Y +F+  V +SRIF+ A+FPHQ + G   G++LG ++  +     P +++     FS+ L G       +L   GI + W+   A + C  ++W   +  PF  +    R AGVL G G++
Sbjct:   11 MAEALQQKSRSLEDMWLVASHMGDPKAAVLLVFPVVFYIHRRTGIAVLWVAALSEWLNLVLKWILFGERPYWWIGQSGLFSEKPPEVQ--QFQSTCESGPGSPSGHAMVTSAVWWVIVSSLASFSQAYTGSKILSAVLYLLYAVFLGCVGLSRIFILAHFPHQVVAGFLTGVLLGVFLKRSVPERRPLLFFF---RFSMALLGAALIFHAVLEKTGIDLSWSISLAKRWCSRSEWVRMDTAPFSSL---NRDAGVLLGLGLA 264          
BLAST of Glucose-6-phosphatase vs. Ensembl Zebrafish
Match: BX005142.2 (glucose-6-phosphatase b, catalytic subunit [Source:NCBI gene;Acc:100000750])

HSP 1 Score: 125.561 bits (314), Expect = 5.341e-32
Identity = 81/254 (31.89%), Postives = 129/254 (50.79%), Query Frame = 2
Query:  179 IQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNV--GKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGN-YVASTKLYNSPSVYYLYASAFSVILS-GLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIFPFFRSAGVLAGTGISLLL 922
            +Q  +    S    +S I+D    F F FPI ++    +G+ ++W     D L +VLK     +RPYWWV + V  G +    I Q+P+TC   PG PSGH +  + VY+A++  L     +C +  L   +    + V++SR+F+AA+FPHQ I GVF GI +   +   + +Y++    Y++     V ++ GLY+ L     I   W+   A K C  ++W   +  PF  +    R+ G L G G+SL L
Sbjct:   18 LQKHFGHAQSWFTFVSTIADLRTTFLFFFPIWFHLQSAVGVKLVWVAVVGDWLNLVLKWLMFGERPYWWVRETVYYGNLTVPQIKQFPMTCETGPGSPSGHAMGAAGVYYAMVTSLLLNFKECLQALLWAFFWSVQVCVSLSRVFIAAHFPHQVITGVFSGIAVAKAFNRVSWIYSASLKGYMHTILCLVFVALGLYAVLDA-ASIDPYWSLMKAQKWCIQSEWVHLDTTPFAGL---LRNTGALFGLGLSLHL 267          
BLAST of Glucose-6-phosphatase vs. Ensembl Zebrafish
Match: g6pcb (glucose-6-phosphatase b, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-081223-2])

HSP 1 Score: 125.176 bits (313), Expect = 9.602e-32
Identity = 82/261 (31.42%), Postives = 134/261 (51.34%), Query Frame = 2
Query:  179 IQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNV--GKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSL----TLIYGIF---MILVAVSRIFLAANFPHQAIMGVFFGIVLGN-YVASTKLYNSPSVYYLYASAFSVILS-GLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIFPFFRSAGVLAGTGISLLL 922
            +Q  +    S    +S I+D    F F FPI ++    +G+ ++W     D L +VLK     +RPYWWV + V  G +    I Q+P+TC   PG PSGH +  + VY+A++  L     +C+ +       L++ +F    + V++SR+F+AA+FPHQ I GVF GI +   +   + +Y++    Y+++    V ++ GLY+ L     I   W+   A K C  ++W   +  PF  +    R+ G L G G+SL L
Sbjct:   25 LQKHFGHAQSWFTFVSTIADLRTTFLFFFPIWFHLQSAVGVKLVWVAVVGDWLNLVLKWLMFGERPYWWVRETVYYGNLTVPQIKQFPMTCETGPGSPSGHAMGAAGVYYAMVTSLLLNFKECDPLKRWCLQALLWAVFWSVQVCVSLSRVFIAAHFPHQVIAGVFSGIAVAKAFNRVSWIYSASLKGYMHSILCLVFVALGLYAVLDA-ASIDPYWSLMKAQKWCIQSEWVHLDTTPFAGL---LRNTGALFGLGLSLHL 281          
BLAST of Glucose-6-phosphatase vs. Ensembl Zebrafish
Match: BX005142.2 (glucose-6-phosphatase b, catalytic subunit [Source:NCBI gene;Acc:100000750])

HSP 1 Score: 123.635 bits (309), Expect = 3.773e-31
Identity = 82/261 (31.42%), Postives = 132/261 (50.57%), Query Frame = 2
Query:  179 IQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNV--GKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSL----TLIYGIF---MILVAVSRIFLAANFPHQAIMGVFFGIVLGN-YVASTKLYNSPSVYYLYASAFSVILS-GLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIFPFFRSAGVLAGTGISLLL 922
            +Q  +    S    +S I+D    F F FPI ++    +G+ ++W     D L +VLK     +RPYWWV + V  G +    I Q+P+TC   PG PSGH +  + VY+A++  L     +C+ +       L++  F    + V++SR+F+AA+FPHQ I GVF GI +   +   + +Y++    Y++     V ++ GLY+ L     I   W+   A K C  ++W   +  PF  +    R+ G L G G+SL L
Sbjct:   24 LQKHFGHAQSWFTFVSTIADLRTTFLFFFPIWFHLQSAVGVKLVWVAVVGDWLNLVLKWLMFGERPYWWVRETVYYGNLTVPQIKQFPMTCETGPGSPSGHAMGAAGVYYAMVTSLLLNFKECDPLKRWCLQALLWAFFWSVQVCVSLSRVFIAAHFPHQVITGVFSGIAVAKAFNRVSWIYSASLKGYMHTILCLVFVALGLYAVLDA-ASIDPYWSLMKAQKWCIQSEWVHLDTTPFAGL---LRNTGALFGLGLSLHL 280          
BLAST of Glucose-6-phosphatase vs. Ensembl Zebrafish
Match: g6pca.1 (glucose-6-phosphatase a, catalytic subunit, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-031001-4])

HSP 1 Score: 112.464 bits (280), Expect = 2.684e-27
Identity = 77/258 (29.84%), Postives = 128/258 (49.61%), Query Frame = 2
Query:  161 MEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVG--KNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYW----AILAVLFKWK-----NKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGN--------YVASTKLYNSPSVYYL-YASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIF 868
            +E+   +Q +Y+   S    +S ++D    F   FP+ ++    + + ++W     D L +VLK     +RPYWWV   K  G +    + Q+ +TC   PG PSGH + ++AV +    A+L++L + K      +  ++ L +  G+  +LV +SR++LAA+FPHQ I GV  GI++          Y AS K Y S +++ L +A  F V+L          LG+ + WT   A K C +  W   +  PF  + 
Sbjct:    9 VELAVHLQIKYQDYESVFHWVSSLADLHTTFFVFFPVWFHLRRDVAVKLIWVAVVGDWLNLVLKWVLFGERPYWWVHETKFYGSMKHPELQQFSMTCETGPGSPSGHAMGSAAVGYVMITALLSILAERKLPPLIYRLVQLMLWMFLGLVELLVCMSRVYLAAHFPHQVICGVISGIIVAETFSRVQWIYSASLKKYFSITLFLLSFAVGFYVLLKA--------LGVDLLWTLEKAQKWCINPAWVLMDATPFASLL 258          
BLAST of Glucose-6-phosphatase vs. Ensembl Xenopus
Match: g6pc.1 (glucose-6-phosphatase, catalytic subunit, gene 1 [Source:NCBI gene;Acc:100125173])

HSP 1 Score: 127.102 bits (318), Expect = 2.450e-32
Identity = 92/322 (28.57%), Postives = 146/322 (45.34%), Query Frame = 2
Query:  137 ITELLTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNV--GKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYW----AILAVLFKWK-----NKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKL-YNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALV 1066
            +  L  + +++I+ +Q  YK        +S  +D    F   FPI ++    +G+ ++W     D L +V K      RPYWWV      G     +I Q+P+TC   PG PSGH + ++ +Y+    AI+ ++ K K     N+C   +L   +    + V +SRIFLAA+FPHQ + GV  GIV+      T+L Y +    Y+Y + F    +  +  L   +G+ + WT   A + C   +W +     D  PF   AG+L   GI L L  A   + +     R K+       +  I     V+  FD + P   V
Sbjct:    5 MDALHDSGVQMIQYLQMNYKSSQDWFMFVSFAADLRNTFFIFFPIWFHLCEAVGIKLIWVAVIGDWLNLVFKWILFGQRPYWWVHDTAYYGNSSAPAIEQFPVTCETGPGSPSGHAMGSAGIYYVMVTAIITLMLKKKQTSLTNRCVCGALWAGFWAVQVCVCLSRIFLAAHFPHQVVAGVISGIVVAEAFHHTQLIYKASLKKYIYTTLFLFSFALGFYLLLKAVGVDLLWTLEKAKRWCARPEWIH----IDTTPF---AGLLRNLGIFLGLGLALNSK-LYQESCRGKKGSQFTFRLCCIVASLLVLHLFDSFKPPTKV 318          
BLAST of Glucose-6-phosphatase vs. Ensembl Xenopus
Match: g6pc.1 (glucose-6-phosphatase, catalytic subunit, gene 1 [Source:NCBI gene;Acc:100125173])

HSP 1 Score: 124.79 bits (312), Expect = 1.483e-31
Identity = 86/313 (27.48%), Postives = 142/313 (45.37%), Query Frame = 2
Query:  137 ITELLTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNV--GKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKL-YNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALV 1066
            +  L  + +++I+ +Q  YK        +S  +D    F   FPI ++    +G+ ++W     D L +V K      RPYWWV      G     +I Q+P+TC   PG PSGH + ++ +Y+ ++  +    +  + ++L   +    + V +SRIFLAA+FPHQ + GV  GIV+      T+L Y +    Y+Y + F    +  +  L   +G+ + WT   A + C   +W +     D  PF   AG+L   GI L L  A   + +     R K+       +  I     V+  FD + P   V
Sbjct:    5 MDALHDSGVQMIQYLQMNYKSSQDWFMFVSFAADLRNTFFIFFPIWFHLCEAVGIKLIWVAVIGDWLNLVFKWILFGQRPYWWVHDTAYYGNSSAPAIEQFPVTCETGPGSPSGHAMGSAGIYYVMVTAIITLIDCDQVVTLWAGFWAVQVCVCLSRIFLAAHFPHQVVAGVISGIVVAEAFHHTQLIYKASLKKYIYTTLFLFSFALGFYLLLKAVGVDLLWTLEKAKRWCARPEWIH----IDTTPF---AGLLRNLGIFLGLGLALNSK-LYQESCRGKKGSQFTFRLCCIVASLLVLHLFDSFKPPTKV 309          
BLAST of Glucose-6-phosphatase vs. Ensembl Xenopus
Match: G6PC3 (glucose 6 phosphatase, catalytic, 3, gene 1 [Source:NCBI gene;Acc:779477])

HSP 1 Score: 122.479 bits (306), Expect = 7.734e-31
Identity = 67/235 (28.51%), Postives = 118/235 (50.21%), Query Frame = 2
Query:  221 ISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSLT--LIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTN--QNPFQDIFPFFRSAGVLAGTGIS 913
            ++ + DP   +   FP+ Y     +G+ ILWT   ++ L ++ K     +RP+WW+ ++ G   D+ + Q+PLTC   PG PSGHC++T A  W ++      + +   +SL   ++Y + M+ VA+SR+ + A+FPHQ + G+  G+ LG+ +  T       +++   S   +  + L  F   + G+ + W+   A K C   +W      PF  +    RSA    G G +
Sbjct:   31 VNHLGDPAHIYVIYFPLAYCICNRLGVAILWTGLLSEWLNLIFKWFLFGERPFWWIYES-GMHSDLHLTQFPLTCETGPGSPSGHCMITGAALWPVMMFFTNLRPQRTLLSLVPIILYIMLMVGVAISRVLILAHFPHQVVAGLIAGMYLGHSIPGTVSRGCTLLFFTLTSVLLLFGAFLIYFGMGIFGVDLSWSINRATKWCAKPEWVRLETRPFSSV---TRSAASALGLGFA 261          
BLAST of Glucose-6-phosphatase vs. Ensembl Xenopus
Match: g6pc.2 (glucose-6-phosphatase, catalytic subunit, gene 2 [Source:NCBI gene;Acc:100127753])

HSP 1 Score: 120.939 bits (302), Expect = 3.559e-30
Identity = 77/273 (28.21%), Postives = 138/273 (50.55%), Query Frame = 2
Query:  137 ITELLTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDV--SIAQYPLTCAILPGGPSGHCLVTSAVYW----AILAVLFKWK----NKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTK-LYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDW--TNQNPFQDIFPFFRSAGVLAGTGISL 916
            +  L +  + I++ +Q  +         +S  +D    F  +FPI ++    +G+ ++W     D L +V K      RPYWWV +    +     +I Q+P+TC   PG PSGH + +S+VY+    A+L++L + K    ++ ++ +L L +    + V +SR+F+AA+FPHQ I GVF G+++       + +YN+    YL+A+ F    +  +  L  + G+ + WT   A + C   +W   +  PF  +    R+ GV  G G++L
Sbjct:    5 MENLHSTGVHIVQYLQENFIKSQDWFVFVSFAADLKNTFLVLFPIWFHLSESVGIKLVWVAVIGDWLNLVFKWILFGQRPYWWVHETTFFINSSAPTILQFPVTCETGPGSPSGHAMGSSSVYYVMAHAVLSILLENKTSLMSRFQRWALWLFFWSVQVNVCLSRVFVAAHFPHQVIAGVFSGMLVAEMFNHIQCIYNASFKRYLHATLFLFFFALGFFLLLKVFGVDLLWTLEKAKRWCARPEWIHIDTTPFAGL---LRNLGVFFGLGLAL 274          
BLAST of Glucose-6-phosphatase vs. Ensembl Xenopus
Match: arl11 (ADP ribosylation factor like GTPase 11 [Source:Xenbase;Acc:XB-GENE-1012125])

HSP 1 Score: 117.087 bits (292), Expect = 1.046e-28
Identity = 73/275 (26.55%), Postives = 128/275 (46.55%), Query Frame = 2
Query:  137 ITELLTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVL----------FKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTK-LYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDW--TNQNPFQDIFPFFRSAGVLAGTGISL 916
            +  L  + ++++  +Q  Y+        IS  +D    F  +FPI ++    +G+ ++W     D L +V K      RPYWWV        +    I Q+P+TC   PG PSGH + ++ +Y+ I+  L          F ++ KC +  L   + +    V +SR+FLAA+FPHQ I GV  G+V+       + +Y +    Y+Y + F    +  +  +   +G+ + WT   A + C   +W   +  PF  +    R+ G+  G G++L
Sbjct:    5 MDALHHSGVQMVHYLQVNYETSQDWFVFISFAADLRNTFFILFPIWFHLCESVGIKLIWVAVIGDWLNLVFKWILFGQRPYWWVHDTDYYNNMSAPVIQQFPVTCETGPGSPSGHAMGSAGIYYVIVTALVTLFLQKKQSFSFQKKCFQALLWSGFWVIQACVCLSRVFLAAHFPHQVICGVIAGMVVAEVFEHIQSIYKASLNKYIYTTLFLFCFALGFYLVLKTVGVDLLWTIEKAKRWCSQPEWIHIDTTPFAGL---LRNLGIFFGLGLAL 276          
BLAST of Glucose-6-phosphatase vs. Ensembl Mouse
Match: G6pc3 (glucose 6 phosphatase, catalytic, 3 [Source:MGI Symbol;Acc:MGI:1915651])

HSP 1 Score: 126.716 bits (317), Expect = 1.964e-32
Identity = 89/324 (27.47%), Postives = 154/324 (47.53%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN-VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILA-----VLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVA-STKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQN--PFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALVYFSKTFMEF 1093
            L+A + + E +Q +   + +    ++ + DP   F F FP  YY+   +G+ +LW    A+ L +V K     DRP+WWV ++       + I Q+P +C   PG PSGHC++T A  W ++      V  + ++   ++   L Y  F++ V +SR+FL A+FPHQ + G+  G  LG  ++    +    S Y L A A  +  S +Y  L   LG+ + W+   A K C   +W + +  PF  +    R +G   G GI+L      Q R   L   +   C  + + ++       V   +  YPP+  +++   F+++
Sbjct:    5 LSAGIIMAEALQNRLPGLENMWLWVTFLGDPKNLFQFCFPAAYYASRRLGISVLWITFIAEWLNLVFKWFLFGDRPFWWVHESGYSTQTPIQIHQFPSSCETGPGSPSGHCMITGAALWPVMTAISSQVASRSRSPWVRVIPGLAYCTFLLAVGLSRVFLLAHFPHQVLGGLIVGAALGWLMSPRVPMERELSFYGLTALALMLGASLMYWTLF-TLGLDLSWSINLASKWCERPEWVHMDSRPFASL---SRDSGSALGLGIALHTPCYAQIRRAHLGNGQKIACFVLAMGLL-------VFLEWLGYPPQISLFYIFNFLKY 317          
BLAST of Glucose-6-phosphatase vs. Ensembl Mouse
Match: G6pc3 (glucose 6 phosphatase, catalytic, 3 [Source:MGI Symbol;Acc:MGI:1915651])

HSP 1 Score: 126.716 bits (317), Expect = 1.964e-32
Identity = 89/324 (27.47%), Postives = 154/324 (47.53%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN-VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILA-----VLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVA-STKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQN--PFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALVYFSKTFMEF 1093
            L+A + + E +Q +   + +    ++ + DP   F F FP  YY+   +G+ +LW    A+ L +V K     DRP+WWV ++       + I Q+P +C   PG PSGHC++T A  W ++      V  + ++   ++   L Y  F++ V +SR+FL A+FPHQ + G+  G  LG  ++    +    S Y L A A  +  S +Y  L   LG+ + W+   A K C   +W + +  PF  +    R +G   G GI+L      Q R   L   +   C  + + ++       V   +  YPP+  +++   F+++
Sbjct:    5 LSAGIIMAEALQNRLPGLENMWLWVTFLGDPKNLFQFCFPAAYYASRRLGISVLWITFIAEWLNLVFKWFLFGDRPFWWVHESGYSTQTPIQIHQFPSSCETGPGSPSGHCMITGAALWPVMTAISSQVASRSRSPWVRVIPGLAYCTFLLAVGLSRVFLLAHFPHQVLGGLIVGAALGWLMSPRVPMERELSFYGLTALALMLGASLMYWTLF-TLGLDLSWSINLASKWCERPEWVHMDSRPFASL---SRDSGSALGLGIALHTPCYAQIRRAHLGNGQKIACFVLAMGLL-------VFLEWLGYPPQISLFYIFNFLKY 317          
BLAST of Glucose-6-phosphatase vs. Ensembl Mouse
Match: G6pc2 (glucose-6-phosphatase, catalytic, 2 [Source:MGI Symbol;Acc:MGI:1277193])

HSP 1 Score: 114.775 bits (286), Expect = 5.215e-28
Identity = 78/275 (28.36%), Postives = 133/275 (48.36%), Query Frame = 2
Query:  167 IIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVS---IAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWK-NKCEKMSLTL----------IYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVL--------GNYVASTKLYNSPSVY-YLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDW--TNQNPFQDIFPFFRSAGVLAGTGISL 916
            II  +Q  Y+     L  +S + DP   F   FP+ +     +G  ++W     D   ++ K      RPYWW+ +     P+ S   + Q+P TC   PG PSGH + +S V++ ++     +  ++ E+ S+TL          ++ +  I V +SR+F+A +FPHQ I+GV  G+++        G ++AS  +Y   +V+ +L+A  F ++L         L GI + W+   A K C + DW   +  PF  +    R+ GVL G G ++
Sbjct:   11 IIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWFQLNQNVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWI-QETEIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTISRMEESSVTLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGVHMASLSVYLKTNVFLFLFALGFYLLLR--------LFGIDLLWSVPIAKKWCANPDWIHIDSTPFAGL---VRNLGVLFGLGFAI 273          
BLAST of Glucose-6-phosphatase vs. Ensembl Mouse
Match: G6pc (glucose-6-phosphatase, catalytic [Source:MGI Symbol;Acc:MGI:95607])

HSP 1 Score: 107.071 bits (266), Expect = 2.885e-25
Identity = 77/254 (30.31%), Postives = 121/254 (47.64%), Query Frame = 2
Query:  179 IQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGK----NVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILA---VLFKWKNK------CEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGI--------VLGNYVASTKLYNSPSVY-YLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIF 868
            +Q  Y+        +S+I+D   AF  +FPI ++    +G+ +LW     D   +V K      RPYWWV      +   VP   I Q+P+TC   PG PSGH +  + VY+ ++     +F+ K K      C  + L L +    + V +SRI+LAA+FPHQ + GV  GI        + G Y AS + Y   +++ + +A  F ++L G        LG+ + WT   A + C   +W   +  PF  +F
Sbjct:   19 LQVNYQDSQDWFILVSVIADLRNAFYVLFPIWFHLKETVGINLLWVAVVGDWFNLVFKWILFGQRPYWWVLDTDYYSNSSVP--IIKQFPVTCETGPGSPSGHAMGAAGVYYVMVTSTLAIFRGKKKPTYGFRCLNVILWLGFWAVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVAETFSHIRGIYNASLRKYCLITIFLFGFALGFYLLLKG--------LGVDLLWTLEKAKRWCERPEWVHLDTTPFASLF 262          
BLAST of Glucose-6-phosphatase vs. Ensembl Mouse
Match: G6pc2 (glucose-6-phosphatase, catalytic, 2 [Source:MGI Symbol;Acc:MGI:1277193])

HSP 1 Score: 70.4774 bits (171), Expect = 4.650e-14
Identity = 38/136 (27.94%), Postives = 65/136 (47.79%), Query Frame = 2
Query:  167 IIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVS---IAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWK-NKCEKMSLTL 562
            II  +Q  Y+     L  +S + DP   F   FP+ +     +G  ++W     D   ++ K      RPYWW+ +     P+ S   + Q+P TC   PG PSGH + +S V++ ++     +  ++ E+ S+TL
Sbjct:   11 IIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWFQLNQNVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWI-QETEIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTISRMEESSVTL 145          
BLAST of Glucose-6-phosphatase vs. UniProt/SwissProt
Match: sp|A1A5Z0|G6PC3_DANRE (Glucose-6-phosphatase 3 OS=Danio rerio OX=7955 GN=g6pc3 PE=2 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 4.915e-34
Identity = 82/262 (31.30%), Postives = 133/262 (50.76%), Query Frame = 2
Query:  167 IIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN---VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWK-----NKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLL---GIQIKWTFCAADKHCYDTDWTNQN--PFQDIFPFFRSAGVLAGTGIS 913
            + E +Q   + +       S + DP  A   VFP+ +Y     G+ +LW    ++ L +V K     +RPYWW+G++     K P+V   Q+  TC   PG PSGH +VTSAV+W I++ L  +      +K     L L+Y +F+  V +SRIF+ A+FPHQ + G+  G++LG ++  +     P +++     FS+ L G       +L   GI + W+   A + C  ++W   +  PF  +    R AGVL G G++
Sbjct:   11 MAEALQQNSRSLEDLWLVASHMGDPKAAVLLVFPVVFYIHRRTGIAVLWVAALSEWLNLVFKWILFGERPYWWIGQSGLFSEKPPEVQ--QFQSTCESGPGSPSGHAMVTSAVWWVIISSLASFSQAYTGSKILSAVLYLLYAVFLGCVGLSRIFILAHFPHQVVAGLLTGVLLGVFLKRSVPERRPLLFFF---RFSMALLGAALIFHAVLEKTGIDLSWSISLAKRWCSRSEWVRMDTAPFSSL---NRDAGVLLGLGLA 264          
BLAST of Glucose-6-phosphatase vs. UniProt/SwissProt
Match: sp|Q9BUM1|G6PC3_HUMAN (Glucose-6-phosphatase 3 OS=Homo sapiens OX=9606 GN=G6PC3 PE=1 SV=2)

HSP 1 Score: 129.413 bits (324), Expect = 1.606e-32
Identity = 87/295 (29.49%), Postives = 143/295 (48.47%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVL-----FKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVA-STKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDW--TNQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSII 1003
            L A + I E +Q Q   + +    I+ + DP + F F FP  YY+   +G+ +LW     + L ++ K     DRP+WWV ++    + P   + Q+P +C   PG PSGHC++T A  W I+  L      + +++  ++  +L Y  F++ V +SRIF+ A+FPHQ + G+  G VLG  +     +    S Y L A A  +  S +Y  L   LG+ + W+   A K C   +W   +  PF  +    R +G   G GI+L      Q R   L   +   C+ + + ++
Sbjct:    5 LGAGIVIAEALQNQLAWLENVWLWITFLGDPKILFLFYFPAAYYASRRVGIAVLWISLITEWLNLIFKWFLFGDRPFWWVHESGYYSQAP-AQVHQFPSSCETGPGSPSGHCMITGAALWPIMTALSSQVATRARSRWVRVMPSLAYCTFLLAVGLSRIFILAHFPHQVLAGLITGAVLGWLMTPRVPMERELSFYGLTALALMLGTSLIYWTLF-TLGLDLSWSISLAFKWCERPEWIHVDSRPFASL---SRDSGAALGLGIALHSPCYAQVRRAQLGNGQKIACLVLAMGLL 294          
BLAST of Glucose-6-phosphatase vs. UniProt/SwissProt
Match: sp|Q6AZ83|G6PC3_RAT (Glucose-6-phosphatase 3 OS=Rattus norvegicus OX=10116 GN=G6pc3 PE=2 SV=1)

HSP 1 Score: 127.487 bits (319), Expect = 7.414e-32
Identity = 85/325 (26.15%), Postives = 159/325 (48.92%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAIL-----AVLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPL-LGIQIKWTFCAADKHCYDTDW--TNQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALVYFSKTFMEF 1093
            L+A + + E +Q Q   + +    ++ ++DP   F F FP  YY+   +G+ + W     + L +V K     DRP+WWV ++    + P V I Q+P +C   PG PSGHC++T A  W ++      V  + ++   ++   L Y  F++ V +SR+FL A+FPHQ + G+  G++LG ++ S ++     + +   +A +++L     + +   LG+ + W+   A K C   +W   +  PF  +    R +G   G GI+L      Q R + L   +   C  + + ++       V   +  +PP+  +++   F++F
Sbjct:    5 LSAGIMMAEALQNQLPGLENMWLWVTFLADPKNLFQFYFPAVYYASRRLGISLFWIAFITEWLNLVFKWFLFGDRPFWWVHESGYSAQTP-VQIHQFPSSCETGPGSPSGHCMITGAALWPVMIAISSQVASQTRSPWVRVIPGLAYCTFLLAVGLSRVFLLAHFPHQVLAGLLAGVILG-WLLSPRVPMERELSFYGLTALTLMLGASLMYWTLFTLGLDLSWSINLASKWCDRPEWVLVDSRPFASL---SRDSGSALGLGIALHTPCYAQIRRVHLGNGQKIACFVLAMGLL-------VFLEWLGHPPQISLFYIFNFLKF 317          
BLAST of Glucose-6-phosphatase vs. UniProt/SwissProt
Match: sp|Q6NSQ9|G6PC3_MOUSE (Glucose-6-phosphatase 3 OS=Mus musculus OX=10090 GN=G6pc3 PE=1 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 1.374e-31
Identity = 89/324 (27.47%), Postives = 154/324 (47.53%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN-VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILA-----VLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVA-STKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQN--PFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALVYFSKTFMEF 1093
            L+A + + E +Q +   + +    ++ + DP   F F FP  YY+   +G+ +LW    A+ L +V K     DRP+WWV ++       + I Q+P +C   PG PSGHC++T A  W ++      V  + ++   ++   L Y  F++ V +SR+FL A+FPHQ + G+  G  LG  ++    +    S Y L A A  +  S +Y  L   LG+ + W+   A K C   +W + +  PF  +    R +G   G GI+L      Q R   L   +   C  + + ++       V   +  YPP+  +++   F+++
Sbjct:    5 LSAGIIMAEALQNRLPGLENMWLWVTFLGDPKNLFQFCFPAAYYASRRLGISVLWITFIAEWLNLVFKWFLFGDRPFWWVHESGYSTQTPIQIHQFPSSCETGPGSPSGHCMITGAALWPVMTAISSQVASRSRSPWVRVIPGLAYCTFLLAVGLSRVFLLAHFPHQVLGGLIVGAALGWLMSPRVPMERELSFYGLTALALMLGASLMYWTLF-TLGLDLSWSINLASKWCERPEWVHMDSRPFASL---SRDSGSALGLGIALHTPCYAQIRRAHLGNGQKIACFVLAMGLL-------VFLEWLGYPPQISLFYIFNFLKY 317          
BLAST of Glucose-6-phosphatase vs. UniProt/SwissProt
Match: sp|Q148G2|G6PC3_BOVIN (Glucose-6-phosphatase 3 OS=Bos taurus OX=9913 GN=G6PC3 PE=2 SV=1)

HSP 1 Score: 123.635 bits (309), Expect = 1.819e-30
Identity = 90/325 (27.69%), Postives = 153/325 (47.08%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVL-----FKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVA-STKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALVYFSKTFMEF 1093
            L A + + E +Q Q   + +    ++ + DP   F F FP  YY+   +G+ +LW     + L +V K     DRP+WWV ++    + P   + Q+P +C   PG PSGHC++T A  W I+  +      +  ++  ++  +L Y  F++ V +SR+FL A+FPHQ + G+  G VLG  +     +    S Y L + A  +  S +Y  L   LG+ + W+   A K C   +W   +  PF  +    R +G   G GI+L      Q R   L   +   C      ++L  G    ++    YPP+  +++   F+++
Sbjct:    5 LGAGIAMAEALQNQLPWLENVWLWVTFLGDPKSLFLFYFPAAYYASRRVGIAVLWISLITEWLNLVFKWFLFGDRPFWWVHESGYYSQAP-AQVHQFPSSCETGPGSPSGHCMITGAALWPIMTAVSSQMATRAHSRWVRVIPSLAYCTFLLAVGLSRVFLLAHFPHQVLAGLITGAVLGWLMTPQVPMERELSFYGLTSLALLLGASLIYWTLF-TLGLDLSWSINLASKWCERPEWVHLDSRPFASL---SRDSGAALGLGIALHSPCYAQVRRAHLGYGQKLVC------LVLAMGLLGPLNWLG-YPPQISLFYIFNFLKY 317          
BLAST of Glucose-6-phosphatase vs. TrEMBL
Match: F7G6N4 (Glucose-6-phosphatase OS=Monodelphis domestica OX=13616 GN=G6PC3 PE=3 SV=2)

HSP 1 Score: 137.887 bits (346), Expect = 3.256e-33
Identity = 91/293 (31.06%), Postives = 149/293 (50.85%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAIL-----AVLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSP-SVYYLYASAFSVILSGLY-SFLSPLLGIQIKWTFCAADKHCYDTDWTNQ--NPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVIL 994
            L A + + ET+Q Q   +      ++ + DP   F F FP+ YY+   +G+ +LW    ++ L ++ K     DRP+WWV ++    + P   + Q+P++C   PG PSGHC++T A  W I+      +  +  ++  K+  +L Y  F++ V +SRIF+ A+FPHQ + G+  G +LG ++      + P S Y L A A  +  S +Y S +S  LGI + W+   A K C   +W +    PF  +    R +G   G GI+L      Q R I L   +   C+S++L
Sbjct:    5 LGAGIVVAETLQNQLPWLEDVWLWVTFLGDPKCIFFFYFPLAYYTCRHVGISVLWITLLSEWLNLIFKWFLFGDRPFWWVHESGYYSQTP-AQVHQFPVSCETGPGSPSGHCMITGAALWPIMIATSAQIAKRSHSRWMKLIPSLAYSTFLLAVGLSRIFILAHFPHQVLGGLIAGALLGWWMTPRVPVDRPVSFYGLTALALLMSTSLIYWSLVS--LGIDMTWSIHLASKWCERPEWVHMETRPFASL---SRDSGAALGLGIALHSPFYAQVRRIQLGTLQQTACLSLVL 291          
BLAST of Glucose-6-phosphatase vs. TrEMBL
Match: A0A3B4B541 (Glucose-6-phosphatase OS=Periophthalmus magnuspinnatus OX=409849 PE=3 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 3.430e-33
Identity = 81/266 (30.45%), Postives = 136/266 (51.13%), Query Frame = 2
Query:  161 MEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCE---------KMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTK-LYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQN--PFQDIFPFFRSAGVLAGTGISL 916
            +E+   +Q +Y          S ++D  M F   FPI ++    I + ++W     D L +VLK     +RPYWWV +    GK P  S+ Q+P+TC   PG PSGH +  +AV++ ++  L     + +         +M LT + G+ +++V +SR+++AA+FPHQ I GV  GI +   V+  K +Y++    YL+ + F    +  +  L   LG+ + WT   A K C  ++W + +  PF  +   FR+ G + G G+ L
Sbjct:    9 VELAVHLQTRYHSYEGLFSFASSVADLHMTFFLFFPIWFHLRRDIAIRLIWVAVIGDWLNLVLKWVLFGERPYWWVHETRFYGKGPAPSLQQFPITCETGPGSPSGHAMGAAAVWYVMITALLSLATEKQCPPLLYKFLQMGLTALMGVILLVVCMSRVYMAAHFPHQVIAGVLTGIYVAMVVSRFKWIYSASLNRYLFTTLFLTSFAVGFYLLLKALGVDLLWTMEKAQKWCVHSEWVHLDTAPFASL---FRNMGTICGVGLGL 271          
BLAST of Glucose-6-phosphatase vs. TrEMBL
Match: H0UYY0 (Glucose-6-phosphatase OS=Cavia porcellus OX=10141 GN=G6PC3 PE=3 SV=2)

HSP 1 Score: 137.887 bits (346), Expect = 3.534e-33
Identity = 89/325 (27.38%), Postives = 159/325 (48.92%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVL-----FKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVA-STKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALVYFSKTFMEF 1093
            L+A +++ E +Q +   + S    ++ + DP   F   FP  YY+   +G+ +LWT    + L +V K     DRP+WWV ++    + P   + Q+P +C   PG PSGHC++T A  W ++  L      + +++  +   +L Y  F++ + +SRIFL A+FPHQ + G+  G VLG  +     +    S Y L A A  +  S +Y  L   LG+ + W+   A K C   +W   +  PF  +    R +G   G GI+L      Q R + L   +   C+++ + ++          ++  +PP+A +++   F+++
Sbjct:    5 LSAGIQMAEALQTRLPWLESMWLWVTFLGDPKSLFLLYFPAAYYASRRVGVAVLWTSLITEWLNLVCKWFLFGDRPFWWVHESGYYSQAP-AQVHQFPSSCETGPGSPSGHCMITGAALWPVMTALSSQVAARSRSRWVRAMPSLAYCTFLLAIGLSRIFLLAHFPHQVLAGLVTGAVLGWLMTPRVPMERELSFYGLTALALMLGASLIYWTLI-TLGLDLSWSINLASKWCERPEWVHIDSRPFASL---SRDSGAALGLGIALHSPCYVQVRRVRLASSQKVACLALAMGLLGAL-------SWLGHPPQASLFYVFNFLKY 317          
BLAST of Glucose-6-phosphatase vs. TrEMBL
Match: A0A2K6FPD8 (Glucose-6-phosphatase OS=Propithecus coquereli OX=379532 GN=G6PC3 PE=3 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 7.614e-33
Identity = 84/266 (31.58%), Postives = 137/266 (51.50%), Query Frame = 2
Query:  149 LTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVL-----FKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVA-STKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQN--PFQDIFPFFRSAGVLAGTGISL 916
            L A + I E +Q Q   + +    ++ + DP + F F FP+ YY+   +G+ +LW     + L +V K     DRP+WWV ++    + P V + Q+P +C   PG PSGHC++T A  W I+  L      + +++  +M  +L Y  F+++V +SR+F+ A+FPHQ + G+  G VLG  +A    +    S Y L A    +  S +Y  L   LG+ + W+   A K C   +W + +  PF  +    R +G   G GI+L
Sbjct:    5 LGAGIAIAEALQNQLPWLENVWLWVTFLGDPKILFLFYFPVAYYASRRVGIAVLWISLITEWLNLVFKWFLFGDRPFWWVHESGYYSQAP-VQVHQFPSSCETGPGSPSGHCMITGAALWPIMMALSSQVATRTRSRWVRMIPSLAYCTFLLMVGLSRVFILAHFPHQVLAGLITGAVLGWLMAPRVPMERELSFYGLTALTLMLGASLIYWTLV-TLGLDVSWSISLASKWCERPEWVHMDSRPFASL---SRDSGAALGLGIAL 265          
BLAST of Glucose-6-phosphatase vs. TrEMBL
Match: F1QI88 (Glucose-6-phosphatase OS=Danio rerio OX=7955 GN=g6pc3 PE=1 SV=1)

HSP 1 Score: 134.806 bits (338), Expect = 3.633e-32
Identity = 83/262 (31.68%), Postives = 134/262 (51.15%), Query Frame = 2
Query:  167 IIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN---VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWK-----NKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLL---GIQIKWTFCAADKHCYDTDWTNQN--PFQDIFPFFRSAGVLAGTGIS 913
            + E +Q + + +       S + DP  A   VFP+ +Y     G+ +LW    ++ L +VLK     +RPYWW+G++     K P+V   Q+  TC   PG PSGH +VTSAV+W I++ L  +      +K     L L+Y +F+  V +SRIF+ A+FPHQ + G   G++LG ++  +     P +++     FS+ L G       +L   GI + W+   A + C  ++W   +  PF  +    R AGVL G G++
Sbjct:   11 MAEALQQKSRSLEDMWLVASHMGDPKAAVLLVFPVVFYIHRRTGIAVLWVAALSEWLNLVLKWILFGERPYWWIGQSGLFSEKPPEVQ--QFQSTCESGPGSPSGHAMVTSAVWWVIVSSLASFSQAYTGSKILSAVLYLLYAVFLGCVGLSRIFILAHFPHQVVAGFLTGVLLGVFLKRSVPERRPLLFFF---RFSMALLGAALIFHAVLEKTGIDLSWSISLAKRWCSRSEWVRMDTAPFSSL---NRDAGVLLGLGLA 264          
BLAST of Glucose-6-phosphatase vs. Ensembl Cavefish
Match: g6pc3 (glucose-6-phosphatase catalytic subunit 3 [Source:NCBI gene;Acc:103023782])

HSP 1 Score: 125.946 bits (315), Expect = 2.794e-32
Identity = 82/266 (30.83%), Postives = 135/266 (50.75%), Query Frame = 2
Query:  155 AEMEIIETIQYQ-YKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN---VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSLT-----LIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGL--YSFLSPLLGIQIKWTFCAADKHCYDTDWTNQN--PFQDIFPFFRSAGVLAGTGIS 913
            AE    ET +Y+ + + ++HL       DP  AF  VFP+ +Y     G+ +LW    ++ L +V K      RPYWW+G++   V   P V   Q+  +C   PG PSGH +VT AV+W +++ L  + +      +      L Y + +++V +SRIF+ A+FPHQ I G   G++LG  +  T +  S  +++   S+ +++   L  Y+ L   LGI + W+   A + C  ++W      PF  +    R AG L G G++
Sbjct:   12 AEALQTETRRYEDFWLFATHL------GDPKAAFLLVFPLAFYLHRRSGVAVLWVSALSEWLNLVFKWILFGQRPYWWIGESQLFVKNAPKVE--QFQSSCETGPGSPSGHAMVTGAVWWVVVSALASFLHSRTGSKVLAAIPYLFYTLLLVVVGLSRIFILAHFPHQVIGGTITGVILGVLLNRT-VPESRHLWFFLCSSMALLFGALLMYAGLEN-LGIDLSWSISLAKRWCLKSEWVRLETAPFSSL---NRDAGSLLGLGLA 264          
BLAST of Glucose-6-phosphatase vs. Ensembl Cavefish
Match: g6pcb (glucose-6-phosphatase-like [Source:NCBI gene;Acc:103033443])

HSP 1 Score: 118.242 bits (295), Expect = 2.672e-29
Identity = 83/272 (30.51%), Postives = 129/272 (47.43%), Query Frame = 2
Query:  170 IETIQY---QYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNV----GKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLF---------KWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYV-ASTKLYNSPSVYYLYASAFSVILS-GLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIFPFFRSAGVLAGTGISLLLT 925
            I T QY    Y         +S ++D    F   FPI ++    +G+ +LW     D + +VLK     +RPYWW+ + +      VP   I Q+P TC   PG PSGH +  + VY+A++  L            K  C    L  ++    + V +SRIF+AA+FPHQ I GV  GI +   V  ++ +Y++    Y++ + F +  + GLY+ L  +  I   W+   A + C   DW   +  PF  +    R+ G L G G+SL L+
Sbjct:   23 ISTTQYLQLHYGHAHGWFALVSAVADLRTTFLVFFPICFHLHTAVGVKLLWVAVVGDWINLVLKWILFGERPYWWIQETLYYSNSTVPQ--IQQFPTTCETGPGSPSGHAMGAAGVYYAMVTSLMPVLLNGDGDPVKKWCVHGCLWTLFWAVQVSVCLSRIFIAAHFPHQVIAGVLTGIAVAKVVNRASWIYSATLRSYIHTTLFLLSFALGLYTLLE-VASIDPHWSLSKAQRWCLHPDWVRLDTTPFAGL---LRNTGALFGLGLSLHLS 288          
BLAST of Glucose-6-phosphatase vs. Ensembl Cavefish
Match: g6pca.1 (glucose-6-phosphatase-like [Source:NCBI gene;Acc:103023948])

HSP 1 Score: 115.161 bits (287), Expect = 2.764e-28
Identity = 72/244 (29.51%), Postives = 120/244 (49.18%), Query Frame = 2
Query:  179 IQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWV--GKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAV-YWAILAVL-FKWKNKCEKMSLTLIYGIFMIL-------VAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTK-LYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQN--PFQDIF 868
            +Q +Y+   +  + +S ++D    F   FPI ++    + + ++W     D   +VLK     +RPYWWV   K  G  P  ++ Q P+TC   PG PSGH + ++ V Y  + AVL    K KC  +   L+  +  +L       V +SR+++AA+FPHQ I GV  GI++    +  K +Y +    Y   + F ++ +  +  L  +LG+ + WT   A K C +  W N +  PF  + 
Sbjct:   15 LQTEYRAYENWFQLVSSVADLHTTFFIFFPIWFHLKRDVSIKLIWVAVVGDWFNLVLKWVLFGERPYWWVHETKFYGTDPAPALRQVPITCETGPGSPSGHAMGSAGVAYVMVTAVLAIAAKRKCPPLLYCLLQAVLWMLFVVVELQVCMSRVYVAAHFPHQVISGVISGIIVAEVFSRQKWIYRASLQKYFSITVFLLVFAVGFYVLLKVLGVDLLWTLEKAQKWCNNPSWVNMDTSPFASLL 258          
BLAST of Glucose-6-phosphatase vs. Ensembl Cavefish
Match: g6pca.2 (glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-050309-17])

HSP 1 Score: 109.768 bits (273), Expect = 3.530e-26
Identity = 77/253 (30.43%), Postives = 120/253 (47.43%), Query Frame = 2
Query:  173 ETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWA----ILAVLFKWKNKCE------KMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGN--------YVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDI 865
            + +Q  Y+   S    +S  +D    F   FPI ++    +G+ ++W     D L +V K     +RPYWWV +           I Q+P+TC   PG PSGH +  + VY+A    ILA+L   K          + SL  ++    I V +SR+F+AA+FPHQ I GV  G+++          Y AS + Y + +++ L   +F+V   GLY  L   +G+ + WT   A K C +  W   +  PF  +
Sbjct:   56 QYLQTHYRDAQSWFLFVSFAADLRNTFFVFFPIWFHLRESVGIKLIWVAVVGDWLNLVFKWILFGERPYWWVHETPYYSNTSMPHIEQFPMTCETGPGSPSGHAMGAAGVYYAMVTSILAILLSNKKTLSSSAMYLRGSLWALFWTVQICVCLSRVFIAAHFPHQVIAGVITGMIVAEVFNRQKWIYQASLQKYFNITLFLL---SFAV---GLYVLLKA-MGVDLLWTLEKAQKWCVNPAWVHLDTTPFASL 301          
BLAST of Glucose-6-phosphatase vs. Ensembl Cavefish
Match: g6pca.2 (glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-050309-17])

HSP 1 Score: 107.071 bits (266), Expect = 2.541e-25
Identity = 74/237 (31.22%), Postives = 114/237 (48.10%), Query Frame = 2
Query:  221 ISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKN--VGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWA----ILAVLFKWKNKCE------KMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGN--------YVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDI 865
            +S  +D    F   FPI ++    +G+ ++W     D L +V K     +RPYWWV +           I Q+P+TC   PG PSGH +  + VY+A    ILA+L   K          + SL  ++    I V +SR+F+AA+FPHQ I GV  G+++          Y AS + Y + +++ L   +F+V   GLY  L   +G+ + WT   A K C +  W   +  PF  +
Sbjct:   56 VSFAADLRNTFFVFFPIWFHLRESVGIKLIWVAVVGDWLNLVFKWILFGERPYWWVHETPYYSNTSMPHIEQFPMTCETGPGSPSGHAMGAAGVYYAMVTSILAILLSNKKTLSSSAMYLRGSLWALFWTVQICVCLSRVFIAAHFPHQVIAGVITGMIVAEVFNRQKWIYQASLQKYFNITLFLL---SFAV---GLYVLLKA-MGVDLLWTLEKAQKWCVNPAWVHLDTTPFASL 285          
BLAST of Glucose-6-phosphatase vs. Ensembl Sea Lamprey
Match: g6pca.1 (glucose-6-phosphatase a, catalytic subunit, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-031001-4])

HSP 1 Score: 125.176 bits (313), Expect = 1.433e-32
Identity = 78/276 (28.26%), Postives = 138/276 (50.00%), Query Frame = 2
Query:  137 ITELLTAEMEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVS--IAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEK---------MSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTK-LYNSPSVYYLYASA--FSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIFPFFRSAGVLAGTGISL 916
            +  L   E+ +I+ +Q  +    S L+ +S + D   AF   FPI +Y    +G+ ++W     D + ++ K      RPYWWV +    V      + Q+P+TC   PG PSGH + ++ V++ ++  L   +    +          +L   + +  + V +SR+F+AA+FPHQ ++G   G+V+ +   S   ++N+P   Y+  SA  F++ L    + L+  +G+ + WT   A K C   +W   +  PF  +    R+ GVLAGTG++L
Sbjct:    5 MERLHGGEVSVIQHVQSAFSGQQSALDFMSNVGDIRTAFLVYFPICFYLRRDVGIRMVWAAVLGDWVNLMSKWILFGHRPYWWVHETTFYVNSTVPYLQQFPITCETGPGSPSGHAMGSACVWYVMVRALLDSRAVAARGPATRRWLGAALWSAFAVVQLGVGISRLFVAAHFPHQVLLGALAGMVVADLFGSVSCIHNAPLSRYVGTSAALFALALGFYLALLA--VGVDLLWTVAFAKKWCLHPEWVHLDSTPFAGL---VRNLGVLAGTGLAL 275          
BLAST of Glucose-6-phosphatase vs. Ensembl Sea Lamprey
Match: g6pc3 (glucose 6 phosphatase, catalytic, 3 [Source:NCBI gene;Acc:790919])

HSP 1 Score: 104.375 bits (259), Expect = 3.169e-25
Identity = 73/242 (30.17%), Postives = 115/242 (47.52%), Query Frame = 2
Query:  224 SLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWV---GKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKC---EKMSLTLIYGIFMIL---VAVSRIFLAANFPHQ----AIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQNPFQDIFPFFRSAGVLAGTGI 910
            S + DP  A   + P+ +   PG+G  +LW    A+ L +VLK     +RPYWWV   G N   +  + + Q+P TC   PG PSGH +V++A  W +LA     + +    + ++  + YG  + L   V VSRI++ A+FPHQ     + G+F G VLG Y+  T+       + L  S   +  +  Y      LG  I W+   A++ C   +W   +    +    R +G   G G+
Sbjct:   41 SDLGDPRTAHLLLMPLAHGLCPGLGRAVLWVALMAEWLNLVLKWLLFGERPYWWVLESGFNSTGI--LQLEQFPNTCETGPGSPSGHAMVSAAA-WVVLASWTSARLRSIANKWVAWAVSYGTLLALLSAVGVSRIYILAHFPHQVLGGTLAGLFLGQVLGRYLPKTQRLLPYVAWSL--SLLGIAFAMFYGM--QFLGFNINWSVQLAERWCMRREWVRLDT-TPLASLMRDSGTCLGLGL 274          
BLAST of Glucose-6-phosphatase vs. Ensembl Nematostella
Match: EDO32068 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW54])

HSP 1 Score: 114.775 bits (286), Expect = 1.319e-28
Identity = 70/237 (29.54%), Postives = 119/237 (50.21%), Query Frame = 2
Query:  179 IQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSLT--------------LIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFL-------SPLLGIQIKWTFCAADKHCY 826
            +Q  +   + H   IS   DP  +F   FPI Y     IGL++LW+   ++ L ++LK     +RPYWWV +++ K  ++ + QYPLTC   PG PSGH +VT++V   ++  +     K  ++S +              LI+   +++V+VSR+F+A +FPHQ I+G   GI+L   V   ++     +      AF + ++ L+ ++        P L I     +CA  K+ +
Sbjct:   15 LQRTFAPWTKHFLLISHGGDPRNSFLLYFPIAYNFNSAIGLMVLWSAVLSEWLNLILKWMLRGERPYWWVEEHM-KEQNIHLKQYPLTCETGPGSPSGHVMVTASVLCTLMPAITAKLCKLFRVSTSSLTLISVTIQSVCWLIFIAILVVVSVSRVFIATHFPHQVILGALIGILLSLLVQREQVSKITDLIPCICVAFFLAVTALFLYVGLSFVVFDPSLSITKAQQWCADPKYIH 250          
BLAST of Glucose-6-phosphatase vs. Ensembl Medaka
Match: G6PC2 (glucose-6-phosphatase catalytic subunit 2 [Source:NCBI gene;Acc:101156928])

HSP 1 Score: 120.939 bits (302), Expect = 2.056e-30
Identity = 77/270 (28.52%), Postives = 129/270 (47.78%), Query Frame = 2
Query:  167 IIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGK----NVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCE-------------KMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGN-YVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDIFPFFRSAGVLAGTGISL 916
            +I+ +Q  YK   + L  +S + DP   F F FP  ++    +G  ++W     D   ++ K   +  RPYWWV +        VP   + QY +TC   PG PSGH + +S V++ ++     +                  ++SL +++    I V VSR+F+A +FPHQ I+G+F G+++   +   T +YN+    YL A+ F +  +  +  L  L+ I   W+   A K C + DW   +  PF  +    R+ G L G G++L
Sbjct:   11 VIQHLQNDYKDYHALLNFMSTVGDPRNIFYFYFPFWFHLSHDVGTKMIWVAVIGDWFNLIFKWILYGQRPYWWVQETHLYQNHSVP--RLEQYYITCETGPGSPSGHAMGSSCVWYVMITSALNFAKPSTVSSHWSFQRFYLLRLSLWMVFWAIQISVGVSRVFIATHFPHQVILGLFTGVLVAEGFDHITLVYNASFKVYLQANIFLLSFAVCFYLLLTLMDIDPSWSVTKAKKWCANPDWIHLDTTPFAGL---VRNLGALFGLGLAL 275          
BLAST of Glucose-6-phosphatase vs. Ensembl Medaka
Match: g6pca.1 (glucose-6-phosphatase [Source:NCBI gene;Acc:101169348])

HSP 1 Score: 117.472 bits (293), Expect = 3.235e-29
Identity = 70/251 (27.89%), Postives = 124/251 (49.40%), Query Frame = 2
Query:  161 MEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGK----NVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFK--WKNKCEKMSLTL----IYGIFM---ILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTK-LYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDI 865
            +E+   +Q +Y          S ++D    F F+FPI ++     GL ++W     D L +VLK     +RPYWWV +      G+ P   + Q+P+TC   PG PSGH +  + V++ ++  +     + +C  +   L    ++G+F    ++V +SR+F+AA+FPHQ + GV  G+++   V+ +K +YN+    Y + +      +  +  L   LG+ + WT   A K C   +W   +  PF  +
Sbjct:    9 IELAVHLQSRYSQYEEFFRLASTVADLHTTFFFLFPIWFHLRRDTGLRLIWVAVIGDWLNLVLKWVLSGERPYWWVHETQFYRKGEAP--PLQQFPITCETGPGSPSGHAMGAACVWYVMVTAVLSIAAEKRCPPLLYKLLQGGLWGLFFLVELVVCMSRVFMAAHFPHQVVAGVITGVLVAKIVSKSKWMYNASMNKYFFITFHLTFFAVGFYLLLRTLGVDLLWTLDKAQKWCVKPEWIHLDSTPFASL 257          
BLAST of Glucose-6-phosphatase vs. Ensembl Medaka
Match: g6pca.1 (glucose-6-phosphatase [Source:NCBI gene;Acc:101169348])

HSP 1 Score: 117.472 bits (293), Expect = 4.176e-29
Identity = 70/251 (27.89%), Postives = 124/251 (49.40%), Query Frame = 2
Query:  161 MEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGK----NVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFK--WKNKCEKMSLTL----IYGIFM---ILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTK-LYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDI 865
            +E+   +Q +Y          S ++D    F F+FPI ++     GL ++W     D L +VLK     +RPYWWV +      G+ P   + Q+P+TC   PG PSGH +  + V++ ++  +     + +C  +   L    ++G+F    ++V +SR+F+AA+FPHQ + GV  G+++   V+ +K +YN+    Y + +      +  +  L   LG+ + WT   A K C   +W   +  PF  +
Sbjct:    9 IELAVHLQSRYSQYEEFFRLASTVADLHTTFFFLFPIWFHLRRDTGLRLIWVAVIGDWLNLVLKWVLSGERPYWWVHETQFYRKGEAP--PLQQFPITCETGPGSPSGHAMGAACVWYVMVTAVLSIAAEKRCPPLLYKLLQGGLWGLFFLVELVVCMSRVFMAAHFPHQVVAGVITGVLVAKIVSKSKWMYNASMNKYFFITFHLTFFAVGFYLLLRTLGVDLLWTLDKAQKWCVKPEWIHLDSTPFASL 257          
BLAST of Glucose-6-phosphatase vs. Ensembl Medaka
Match: g6pca.1 (glucose-6-phosphatase [Source:NCBI gene;Acc:101169348])

HSP 1 Score: 116.316 bits (290), Expect = 9.470e-29
Identity = 72/250 (28.80%), Postives = 125/250 (50.00%), Query Frame = 2
Query:  161 MEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGK----NVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAIL-AVLFKWKNK----CEKMSLTLIYGIFM---ILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTK-LYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDI 865
            +E+   +Q +Y          S ++D    F F+FPI ++     GL ++W     D L +VLK     +RPYWWV +      G+ P   + Q+P+TC   PG PSGH +  + V++ ++ AVL     K     +++    ++G+F    ++V +SR+F+AA+FPHQ + GV  G+++   V+ +K +YN+    Y + +      +  +  L   LG+ + WT   A K C   +W   +  PF  +
Sbjct:    9 IELAVHLQSRYSQYEEFFRLASTVADLHTTFFFLFPIWFHLRRDTGLRLIWVAVIGDWLNLVLKWVLSGERPYWWVHETQFYRKGEAP--PLQQFPITCETGPGSPSGHAMGAACVWYVMVTAVLSIAAEKRLFPLQRLLQGGLWGLFFLVELVVCMSRVFMAAHFPHQVVAGVITGVLVAKIVSKSKWMYNASMNKYFFITFHLTFFAVGFYLLLRTLGVDLLWTLDKAQKWCVKPEWIHLDSTPFASL 256          
BLAST of Glucose-6-phosphatase vs. Ensembl Medaka
Match: g6pca.2 (glucose-6-phosphatase catalytic subunit [Source:NCBI gene;Acc:101168932])

HSP 1 Score: 106.686 bits (265), Expect = 2.660e-25
Identity = 65/230 (28.26%), Postives = 110/230 (47.83%), Query Frame = 2
Query:  221 ISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVS--IAQYPLTCAILPGGPSGHCLVTSAVYWAI---------LAVLFKWKNKCEKMSL-TLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTK-LYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWT--NQNPFQDI 865
            +S  +D    F   FPI  +    + + ++W     D L +V K     +RPYWWV +      +    I QYP+TC   PG PSGH +  + VY+ +         L+ ++ +K   +   L +L +G+  + V +SR+F+AA+FPHQ + GV  G+++      T+ +Y++    Y Y + F    +  +  L   LG+ + WT   A K C   +W   +  PF  +
Sbjct:   34 VSWAADLRNTFFIFFPIWVHLKASVAIKLIWVAVIGDWLNLVFKWILFGERPYWWVHETAHYANNARPHIEQYPMTCETGPGSPSGHAMGAAGVYYTLVTSILKQINLSAIYNFKKSFKTAGLWSLFWGV-QVCVCLSRVFIAAHFPHQVVAGVITGMIVAEAFNRTQWIYSASMKKYFYTTLFLTSFAVGFYLLLKSLGVDLLWTLDKAQKWCARPEWVHLDTTPFASL 262          
BLAST of Glucose-6-phosphatase vs. Planmine SMEST
Match: SMESG000009458.1 (SMESG000009458.1)

HSP 1 Score: 612.453 bits (1578), Expect = 0.000e+0
Identity = 323/323 (100.00%), Postives = 323/323 (100.00%), Query Frame = 2
Query:  200 MSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALVYFSKTFMEFXXXXXXXXXXXXXXXXXXXXAHFSL 1168
            MSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALVYFSKTFMEFLSIPIIVILLIPKLLNLYEIAHFSL
Sbjct:    1 MSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIILIFGFKCVISTFDKYPPEALVYFSKTFMEFLSIPIIVILLIPKLLNLYEIAHFSL 323          
BLAST of Glucose-6-phosphatase vs. Planmine SMEST
Match: SMESG000064502.1 (SMESG000064502.1)

HSP 1 Score: 160.999 bits (406), Expect = 1.968e-45
Identity = 90/283 (31.80%), Postives = 151/283 (53.36%), Query Frame = 2
Query:  161 MEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFK-WKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLGNYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADKHCYDTDWTNQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHRTKRCVSVILSIIL 1006
            + II+ +QY ++      E IS ++ P +++ FVFPI ++  P  G+ ILW    ++ L  +LK+    DRPYWWV +N      ++I Q+P TC   PG PSGH  VT+A+   +L +  K +   C K    +I    + L+ +SR  L A+FPHQ ++GVF GI++   +   ++Y +  ++Y   +AF + L+ L  F+ P  G    W+   A K+C  + W  +   +    F + A +L  TG+S+L+ SA +   + L Q    R  S  +S+++
Sbjct:   20 IRIIQHLQYFFEPTVPFFELISKLTRPGLSYYFVFPIIFFIGPHFGISILWAAVVSETLNTLLKLLIQGDRPYWWVKENAAHYCRIAIKQFPGTCEFSPGTPSGHTFVTTAILAMLLLMRCKCFPETCTKRITKIISITVIFLICISRTILGAHFPHQVLLGVFLGILVSWILLYCEIYKNSPIFYFRVAAFLMTLAFLSKFVLPQFGFCSCWSVIKAKKYCQHSIWLPRCISRPSITFLKLASILTSTGMSMLIISALKNSKVQLHQCIVIRMFSAFISLLI 302          
BLAST of Glucose-6-phosphatase vs. Planmine SMEST
Match: SMESG000064502.1 (SMESG000064502.1)

HSP 1 Score: 118.242 bits (295), Expect = 4.736e-31
Identity = 60/164 (36.59%), Postives = 93/164 (56.71%), Query Frame = 2
Query:  161 MEIIETIQYQYKIMSSHLECISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHEDRPYWWVGKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAVLFK-WKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVF 649
            + II+ +QY ++      E IS ++ P +++ FVFPI ++  P  G+ ILW    ++ L  +LK+    DRPYWWV +N      ++I Q+P TC   PG PSGH  VT+A+   +L +  K +   C K    +I    + L+ +SR  L A+FPHQ ++GVF
Sbjct:   20 IRIIQHLQYFFEPTVPFFELISKLTRPGLSYYFVFPIIFFIGPHFGISILWAAVVSETLNTLLKLLIQGDRPYWWVKENAAHYCRIAIKQFPGTCEFSPGTPSGHTFVTTAILAMLLLMRCKCFPETCTKRITKIISITVIFLICISRTILGAHFPHQVLLGVF 183          
The following BLAST results are available for this feature:
BLAST of Glucose-6-phosphatase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
G6PC33.344e-3329.49glucose-6-phosphatase catalytic subunit 3 [Source:... [more]
G6PC7.555e-2727.78glucose-6-phosphatase catalytic subunit [Source:HG... [more]
G6PC21.815e-2629.21glucose-6-phosphatase catalytic subunit 2 [Source:... [more]
G6PC21.815e-2629.21glucose-6-phosphatase catalytic subunit 2 [Source:... [more]
G6PC31.250e-1927.80glucose-6-phosphatase catalytic subunit 3 [Source:... [more]
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BLAST of Glucose-6-phosphatase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Glucose-6-phosphatase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
G6P7.868e-825.37gene:FBgn0031463 transcript:FBtr0113017[more]
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BLAST of Glucose-6-phosphatase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
g6pc31.624e-3531.68glucose 6 phosphatase, catalytic, 3 [Source:NCBI g... [more]
BX005142.25.341e-3231.89glucose-6-phosphatase b, catalytic subunit [Source... [more]
g6pcb9.602e-3231.42glucose-6-phosphatase b, catalytic subunit [Source... [more]
BX005142.23.773e-3131.42glucose-6-phosphatase b, catalytic subunit [Source... [more]
g6pca.12.684e-2729.84glucose-6-phosphatase a, catalytic subunit, tandem... [more]
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BLAST of Glucose-6-phosphatase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
g6pc.12.450e-3228.57glucose-6-phosphatase, catalytic subunit, gene 1 [... [more]
g6pc.11.483e-3127.48glucose-6-phosphatase, catalytic subunit, gene 1 [... [more]
G6PC37.734e-3128.51glucose 6 phosphatase, catalytic, 3, gene 1 [Sourc... [more]
g6pc.23.559e-3028.21glucose-6-phosphatase, catalytic subunit, gene 2 [... [more]
arl111.046e-2826.55ADP ribosylation factor like GTPase 11 [Source:Xen... [more]
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BLAST of Glucose-6-phosphatase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
G6pc31.964e-3227.47glucose 6 phosphatase, catalytic, 3 [Source:MGI Sy... [more]
G6pc31.964e-3227.47glucose 6 phosphatase, catalytic, 3 [Source:MGI Sy... [more]
G6pc25.215e-2828.36glucose-6-phosphatase, catalytic, 2 [Source:MGI Sy... [more]
G6pc2.885e-2530.31glucose-6-phosphatase, catalytic [Source:MGI Symbo... [more]
G6pc24.650e-1427.94glucose-6-phosphatase, catalytic, 2 [Source:MGI Sy... [more]
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BLAST of Glucose-6-phosphatase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A1A5Z0|G6PC3_DANRE4.915e-3431.30Glucose-6-phosphatase 3 OS=Danio rerio OX=7955 GN=... [more]
sp|Q9BUM1|G6PC3_HUMAN1.606e-3229.49Glucose-6-phosphatase 3 OS=Homo sapiens OX=9606 GN... [more]
sp|Q6AZ83|G6PC3_RAT7.414e-3226.15Glucose-6-phosphatase 3 OS=Rattus norvegicus OX=10... [more]
sp|Q6NSQ9|G6PC3_MOUSE1.374e-3127.47Glucose-6-phosphatase 3 OS=Mus musculus OX=10090 G... [more]
sp|Q148G2|G6PC3_BOVIN1.819e-3027.69Glucose-6-phosphatase 3 OS=Bos taurus OX=9913 GN=G... [more]
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BLAST of Glucose-6-phosphatase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
F7G6N43.256e-3331.06Glucose-6-phosphatase OS=Monodelphis domestica OX=... [more]
A0A3B4B5413.430e-3330.45Glucose-6-phosphatase OS=Periophthalmus magnuspinn... [more]
H0UYY03.534e-3327.38Glucose-6-phosphatase OS=Cavia porcellus OX=10141 ... [more]
A0A2K6FPD87.614e-3331.58Glucose-6-phosphatase OS=Propithecus coquereli OX=... [more]
F1QI883.633e-3231.68Glucose-6-phosphatase OS=Danio rerio OX=7955 GN=g6... [more]
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BLAST of Glucose-6-phosphatase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
g6pc32.794e-3230.83glucose-6-phosphatase catalytic subunit 3 [Source:... [more]
g6pcb2.672e-2930.51glucose-6-phosphatase-like [Source:NCBI gene;Acc:1... [more]
g6pca.12.764e-2829.51glucose-6-phosphatase-like [Source:NCBI gene;Acc:1... [more]
g6pca.23.530e-2630.43glucose-6-phosphatase a, catalytic subunit, tandem... [more]
g6pca.22.541e-2531.22glucose-6-phosphatase a, catalytic subunit, tandem... [more]
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BLAST of Glucose-6-phosphatase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
g6pca.11.433e-3228.26glucose-6-phosphatase a, catalytic subunit, tandem... [more]
g6pc33.169e-2530.17glucose 6 phosphatase, catalytic, 3 [Source:NCBI g... [more]
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BLAST of Glucose-6-phosphatase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Glucose-6-phosphatase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO320681.319e-2829.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Glucose-6-phosphatase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
G6PC22.056e-3028.52glucose-6-phosphatase catalytic subunit 2 [Source:... [more]
g6pca.13.235e-2927.89glucose-6-phosphatase [Source:NCBI gene;Acc:101169... [more]
g6pca.14.176e-2927.89glucose-6-phosphatase [Source:NCBI gene;Acc:101169... [more]
g6pca.19.470e-2928.80glucose-6-phosphatase [Source:NCBI gene;Acc:101169... [more]
g6pca.22.660e-2528.26glucose-6-phosphatase catalytic subunit [Source:NC... [more]
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BLAST of Glucose-6-phosphatase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000009458.10.000e+0100.00SMESG000009458.1[more]
SMESG000064502.11.968e-4531.80SMESG000064502.1[more]
SMESG000064502.14.736e-3136.59SMESG000064502.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023565 ID=SMED30023565|Name=Glucose-6-phosphatase|organism=Schmidtea mediterranea sexual|type=transcript|length=1291bp
AATTAATCTCTTATTCAAATAGTTAGTATAAAAATTCTTAACATTGAAAT
CATTGGTGCAAGAAGCGATGGTTCGTTGCAGAAACAGTCTCAATTTCCAG
TGTGGAGAAATCAATCCGAATTACAATTCCTGGTTGATTACAGAACTGTT
AACAGCTGAGATGGAAATTATAGAAACGATTCAATACCAATACAAGATAA
TGTCCTCGCATTTGGAATGTATATCACTGATCAGTGACCCCGTTATGGCT
TTTTGCTTTGTTTTCCCTATCGGATATTATTCAGTGCCAGGAATTGGACT
TTTGATCTTGTGGACATGTACATTTGCAGATATTTTGACCATTGTACTTA
AAATAGCATTTCATGAAGACCGACCTTATTGGTGGGTTGGAAAAAATGTG
GGAAAGGTTCCAGATGTTAGTATTGCTCAATATCCATTGACTTGTGCTAT
CCTTCCGGGTGGGCCATCGGGACATTGCCTTGTTACATCTGCTGTTTATT
GGGCAATATTAGCAGTCCTGTTTAAGTGGAAGAATAAATGCGAGAAGATG
TCACTGACACTTATATATGGGATATTTATGATTCTTGTTGCAGTGAGCAG
GATATTTTTGGCGGCTAATTTCCCTCATCAAGCAATAATGGGAGTATTTT
TTGGTATCGTTCTTGGAAATTATGTAGCTTCTACAAAACTGTACAATTCT
CCGTCTGTTTATTATTTGTATGCCAGTGCCTTTTCTGTGATTTTGAGCGG
ACTTTATTCTTTTCTGTCCCCACTACTCGGAATCCAGATCAAATGGACAT
TTTGCGCAGCAGATAAGCATTGTTACGATACAGATTGGACAAATCAGAAT
CCCTTTCAGGATATTTTCCCATTTTTTCGAAGTGCTGGAGTACTTGCAGG
TACGGGAATATCTTTGTTGCTGACTTCAGCCTTCCAACCACGGATTATTA
TACTGACGCAGCACCGAACGAAACGATGCGTCTCCGTCATATTGTCAATC
ATTCTGATTTTTGGTTTTAAATGTGTGATATCCACATTTGATAAATATCC
ACCAGAAGCTTTGGTATACTTTTCCAAAACATTCATGGAGTTTCTTTCCA
TTCCCATTATTGTTATTTTATTAATACCGAAACTCCTCAATCTCTACGAA
ATTGCCCATTTCTCTCTGTAAAATAAATACTTTGTCATATTTACTAATTT
AATCTAACAAATAGCGTTAATTTTTAATCAAATTTATTTCAAATAGATTT
TTTAAATAAATTTTTGTTTGTTGAAATGAAAAATAAATTTC
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protein sequence of SMED30023565-orf-1

>SMED30023565-orf-1 ID=SMED30023565-orf-1|Name=SMED30023565-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=368bp
MVRCRNSLNFQCGEINPNYNSWLITELLTAEMEIIETIQYQYKIMSSHLE
CISLISDPVMAFCFVFPIGYYSVPGIGLLILWTCTFADILTIVLKIAFHE
DRPYWWVGKNVGKVPDVSIAQYPLTCAILPGGPSGHCLVTSAVYWAILAV
LFKWKNKCEKMSLTLIYGIFMILVAVSRIFLAANFPHQAIMGVFFGIVLG
NYVASTKLYNSPSVYYLYASAFSVILSGLYSFLSPLLGIQIKWTFCAADK
HCYDTDWTNQNPFQDIFPFFRSAGVLAGTGISLLLTSAFQPRIIILTQHR
TKRCVSVILSIILIFGFKCVISTFDKYPPEALVYFSKTFMEFLSIPIIVI
LLIPKLLNLYEIAHFSL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR036938P_Acid_Pase_2/haloperoxi_sf
IPR000326P_Acid_Pase_2/haloperoxidase
IPR016275Glucose-6-phosphatase
Vocabulary: molecular function
TermDefinition
GO:0004346glucose-6-phosphatase activity
GO:0016787hydrolase activity
Vocabulary: cellular component
TermDefinition
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006094gluconeogenesis
GO:0016311dephosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000326Phosphatidic acid phosphatase type 2/haloperoxidaseSMARTSM00014acid_phosph_2coord: 76..204
e-value: 0.0012
score: 27.7
IPR000326Phosphatidic acid phosphatase type 2/haloperoxidasePFAMPF01569PAP2coord: 79..204
e-value: 1.7E-14
score: 53.7
IPR016275Glucose-6-phosphatasePIRSFPIRSF000905G6Pasecoord: 24..364
e-value: 1.6E-49
score: 166.6
NoneNo IPR availableGENE3DG3DSA:1.20.144.10coord: 44..212
e-value: 9.4E-9
score: 36.6
NoneNo IPR availablePANTHERPTHR12591GLUCOSE-6-PHOSPHATASEcoord: 27..358
NoneNo IPR availableTMHMMTMhelixcoord: 49..71
NoneNo IPR availableTMHMMTMhelixcoord: 339..361
NoneNo IPR availableTMHMMTMhelixcoord: 76..98
NoneNo IPR availableTMHMMTMhelixcoord: 267..289
NoneNo IPR availableTMHMMTMhelixcoord: 305..324
NoneNo IPR availableTMHMMTMhelixcoord: 187..204
NoneNo IPR availableTMHMMTMhelixcoord: 163..182
NoneNo IPR availableTMHMMTMhelixcoord: 217..239
IPR036938Phosphatidic acid phosphatase type 2/haloperoxidase superfamilySUPERFAMILYSSF48317Acid phosphatase/Vanadium-dependent haloperoxidasecoord: 65..204