DH domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30023509 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of DH domain-containing protein vs. Ensembl Human
Match: PLEKHG1 (pleckstrin homology and RhoGEF domain containing G1 [Source:HGNC Symbol;Acc:HGNC:20884]) HSP 1 Score: 125.946 bits (315), Expect = 3.254e-28 Identity = 103/333 (30.93%), Postives = 172/333 (51.65%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDK------EVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+QE++ETE YV+ L + E Y+ D I K E +F N +++ F+S L+ L+ + + ++ECF+ + F +Y++YCTNY +SV L A + + Q L H LPL ++LLKPVQRILKYHL+L E+ L VV L A+D M +VA IN+ + + E +R +++ L + + G L+G ++ +N R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++ I +AK+ +L+
Sbjct: 117 VVQEILETERTYVQDLKSIVEDYL---DCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAVLTECMRNKILA-KFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIEN--HLDKDTEGYDVV---LDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKR-DDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAA-KIPAKAKQAILE 433
BLAST of DH domain-containing protein vs. Ensembl Human
Match: PLEKHG1 (pleckstrin homology and RhoGEF domain containing G1 [Source:HGNC Symbol;Acc:HGNC:20884]) HSP 1 Score: 125.946 bits (315), Expect = 3.254e-28 Identity = 103/333 (30.93%), Postives = 172/333 (51.65%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDK------EVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+QE++ETE YV+ L + E Y+ D I K E +F N +++ F+S L+ L+ + + ++ECF+ + F +Y++YCTNY +SV L A + + Q L H LPL ++LLKPVQRILKYHL+L E+ L VV L A+D M +VA IN+ + + E +R +++ L + + G L+G ++ +N R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++ I +AK+ +L+
Sbjct: 117 VVQEILETERTYVQDLKSIVEDYL---DCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAVLTECMRNKILA-KFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIEN--HLDKDTEGYDVV---LDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKR-DDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAA-KIPAKAKQAILE 433
BLAST of DH domain-containing protein vs. Ensembl Human
Match: PLEKHG3 (pleckstrin homology and RhoGEF domain containing G3 [Source:HGNC Symbol;Acc:HGNC:20364]) HSP 1 Score: 119.783 bits (299), Expect = 1.995e-26 Identity = 102/329 (31.00%), Postives = 166/329 (50.46%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYM-KMSDSI-FSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V++E+VETE +YV+ L + E Y+ K+ D+ ++V +F N N+ +S L L NS + ++ CF+E F+ +Y++YC NY SV L A + Q L H LPL ++LLKPVQRILKYHL+L+E+ + VVE A+D M VA IN+ + E +R +++ L + + G L+G +V RN R L + L++ K+ G+ + + I C+ +ML E + L F V +K + ++Q +EK W IK+LI+ ++ H +I ++AK +L+
Sbjct: 97 VVREIVETERMYVQDLRSIVEDYLLKIIDTPGLLKPEQVSALFGNIENIYALNSQLLRDLDSCNSDPVA----VASCFVERSQEFD-IYTQYCNNYPNSVAALTECMRDKQQA-KFFRDRQELLQHSLPLGSYLLKPVQRILKYHLLLQEIAK--HFDEEEDGFEVVED---AIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTYGELVLEGTFRVHRVRNERTFFLFDKTLLITKKRGD-HFVYKGNIPCSSLMLIEST-RDSLCFTVTHYKHSKQQYSIQAKTVEEKRNWTHHIKRLILENH-HATIPQKAKEAILE 411
BLAST of DH domain-containing protein vs. Ensembl Human
Match: PLEKHG1 (pleckstrin homology and RhoGEF domain containing G1 [Source:HGNC Symbol;Acc:HGNC:20884]) HSP 1 Score: 109.383 bits (272), Expect = 1.670e-24 Identity = 87/294 (29.59%), Postives = 156/294 (53.06%), Query Frame = 2
Query: 830 KEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANG-VVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
+E +F N +++ F+S L+ L+ + + ++ECF+ + F +Y++YCTNY +SV L A + + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ + + +L A+D M +VA IN+ + + E +R +++ L + + G L+G ++ +N R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++ I +AK+ +L+
Sbjct: 1 EERSALFGNIQDIYHFNSELLQDLENCENDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAVLTECMRNKILA-KFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHE------IENHLDKDTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKK-RDDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHA-AKIPAKAKQAILE 280
BLAST of DH domain-containing protein vs. Ensembl Human
Match: PLEKHG2 (pleckstrin homology and RhoGEF domain containing G2 [Source:HGNC Symbol;Acc:HGNC:29515]) HSP 1 Score: 98.9821 bits (245), Expect = 2.304e-20 Identity = 76/221 (34.39%), Postives = 116/221 (52.49%), Query Frame = 2
Query: 629 SRPQATVKHIVNKFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMK--MSDSIFS-NDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHA-WQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINE 1279
SRP+ + + L P G + + V +E+VETE YV+ L + E Y+ + + + ++V +F+N ++ F S LE L+ NS SS ++ECF++ F+ +Y+ YC NY S+ L + + A W L + Q QL H LPL +FLLKPVQRILKYHL+L+EL K + G E + +A+ +M VA IN+
Sbjct: 75 SRPEPLPGPPI-RLHLSPVG-IPGSARPSRLERVAREIVETERAYVRDLRSIVEDYLGPLLDGGVLGLSVEQVGTLFANIEDIYEFSSELLEDLE--NS---SSAGGIAECFVQRSEDFD-IYTLYCMNYPSSLALLRELSLSPPAALW--LQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQEL---GKHWAEGPGTGGREMVEEAIVSMTAVAWYIND 282
BLAST of DH domain-containing protein vs. Ensembl Celegans
Match: uig-1 (UNC-112-Interacting Guanine nucleotide exchange factor [Source:UniProtKB/TrEMBL;Acc:H1UBJ0]) HSP 1 Score: 114.775 bits (286), Expect = 1.832e-25 Identity = 102/338 (30.18%), Postives = 175/338 (51.78%), Query Frame = 2
Query: 737 ELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVELIFSNWRNL-RIFHSLFLEKLKLINSYEFSSLQ--RLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQ------SLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINE--KQMXXXXXXXXXXXXXXXYDSD---IFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYI-PKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
EL++TE YV+ L V +GYM D + + +++++ +L +F +L N + + L ++S CF+E G FE Y EYCTNY HRM +T H Q +L + Q L H L LS +LLKPVQRILKYHL L+ +++ +H V+ +A + M A RIN+ K+ E E++ +L+ + + +D I N G L+ + G + +RL+ L E L++ K+ G + + I C+ +ML E+I P++PL F V+ + + + + ++K W + +K++++ Y + I E+ K+++L
Sbjct: 86 ELLDTERTYVEDLNAVIKGYM---DFLVEDREKLKVTLDAISSLFGCIERIFAFNKQLYNQLDAADLDCVKMSRCFVESSGKFED-YIEYCTNY-------HRMMSTLYHLQQQPLVARALQERQLALNHSLQLSAYLLKPVQRILKYHLFLENILKNMPSTTHPEELIQVK---RAHEVMTSQAARINDEKKKAEHIERVGQLQSTLQKWKADEIQISNLSAYGDLLLEATFRQAGSKTTRLLFLFEEMLLIVKQRG-ANYVCKDYIMCSNLMLNEWICPEEPLSFQVLSFDNPRAQYVFMASSMEQKRTWMQELKRMMLDHYSVE-IPEKTKQLML 407
BLAST of DH domain-containing protein vs. Ensembl Celegans
Match: uig-1 (UNC-112-Interacting Guanine nucleotide exchange factor [Source:UniProtKB/TrEMBL;Acc:H1UBJ0]) HSP 1 Score: 114.775 bits (286), Expect = 2.093e-25 Identity = 102/338 (30.18%), Postives = 175/338 (51.78%), Query Frame = 2
Query: 737 ELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVELIFSNWRNL-RIFHSLFLEKLKLINSYEFSSLQ--RLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQ------SLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINE--KQMXXXXXXXXXXXXXXXYDSD---IFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYI-PKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
EL++TE YV+ L V +GYM D + + +++++ +L +F +L N + + L ++S CF+E G FE Y EYCTNY HRM +T H Q +L + Q L H L LS +LLKPVQRILKYHL L+ +++ +H V+ +A + M A RIN+ K+ E E++ +L+ + + +D I N G L+ + G + +RL+ L E L++ K+ G + + I C+ +ML E+I P++PL F V+ + + + + ++K W + +K++++ Y + I E+ K+++L
Sbjct: 269 ELLDTERTYVEDLNAVIKGYM---DFLVEDREKLKVTLDAISSLFGCIERIFAFNKQLYNQLDAADLDCVKMSRCFVESSGKFED-YIEYCTNY-------HRMMSTLYHLQQQPLVARALQERQLALNHSLQLSAYLLKPVQRILKYHLFLENILKNMPSTTHPEELIQVK---RAHEVMTSQAARINDEKKKAEHIERVGQLQSTLQKWKADEIQISNLSAYGDLLLEATFRQAGSKTTRLLFLFEEMLLIVKQRG-ANYVCKDYIMCSNLMLNEWICPEEPLSFQVLSFDNPRAQYVFMASSMEQKRTWMQELKRMMLDHYSVE-IPEKTKQLML 590
BLAST of DH domain-containing protein vs. Ensembl Celegans
Match: uig-1 (UNC-112-Interacting Guanine nucleotide exchange factor [Source:UniProtKB/TrEMBL;Acc:H1UBJ0]) HSP 1 Score: 114.775 bits (286), Expect = 2.345e-25 Identity = 103/341 (30.21%), Postives = 176/341 (51.61%), Query Frame = 2
Query: 737 ELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVELIFSNWRNL-RIFHSLFLEKLKLINSYEFSSLQ--RLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQ------SLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLL---KALDNMLQVANRINE--KQMXXXXXXXXXXXXXXXYDSD---IFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYI-PKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
EL++TE YV+ L V +GYM D + + +++++ +L +F +L N + + L ++S CF+E G FE Y EYCTNY HRM +T H Q +L + Q L H L LS +LLKPVQRILKYHL L+ +++ +H E L+ +A + M A RIN+ K+ E E++ +L+ + + +D I N G L+ + G + +RL+ L E L++ K+ G + + I C+ +ML E+I P++PL F V+ + + + + ++K W + +K++++ Y + I E+ K+++L
Sbjct: 230 ELLDTERTYVEDLNAVIKGYM---DFLVEDREKLKVTLDAISSLFGCIERIFAFNKQLYNQLDAADLDCVKMSRCFVESSGKFED-YIEYCTNY-------HRMMSTLYHLQQQPLVARALQERQLALNHSLQLSAYLLKPVQRILKYHLFLENILKNMPSTTH------PEELIQVKRAHEVMTSQAARINDEKKKAEHIERVGQLQSTLQKWKADEIQISNLSAYGDLLLEATFRQAGSKTTRLLFLFEEMLLIVKQRG-ANYVCKDYIMCSNLMLNEWICPEEPLSFQVLSFDNPRAQYVFMASSMEQKRTWMQELKRMMLDHYSVE-IPEKTKQLML 551
BLAST of DH domain-containing protein vs. Ensembl Celegans
Match: uig-1 (UNC-112-Interacting Guanine nucleotide exchange factor [Source:UniProtKB/TrEMBL;Acc:H1UBJ0]) HSP 1 Score: 114.775 bits (286), Expect = 2.565e-25 Identity = 103/341 (30.21%), Postives = 176/341 (51.61%), Query Frame = 2
Query: 737 ELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVELIFSNWRNL-RIFHSLFLEKLKLINSYEFSSLQ--RLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQ------SLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLL---KALDNMLQVANRINE--KQMXXXXXXXXXXXXXXXYDSD---IFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYI-PKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
EL++TE YV+ L V +GYM D + + +++++ +L +F +L N + + L ++S CF+E G FE Y EYCTNY HRM +T H Q +L + Q L H L LS +LLKPVQRILKYHL L+ +++ +H E L+ +A + M A RIN+ K+ E E++ +L+ + + +D I N G L+ + G + +RL+ L E L++ K+ G + + I C+ +ML E+I P++PL F V+ + + + + ++K W + +K++++ Y + I E+ K+++L
Sbjct: 283 ELLDTERTYVEDLNAVIKGYM---DFLVEDREKLKVTLDAISSLFGCIERIFAFNKQLYNQLDAADLDCVKMSRCFVESSGKFED-YIEYCTNY-------HRMMSTLYHLQQQPLVARALQERQLALNHSLQLSAYLLKPVQRILKYHLFLENILKNMPSTTH------PEELIQVKRAHEVMTSQAARINDEKKKAEHIERVGQLQSTLQKWKADEIQISNLSAYGDLLLEATFRQAGSKTTRLLFLFEEMLLIVKQRG-ANYVCKDYIMCSNLMLNEWICPEEPLSFQVLSFDNPRAQYVFMASSMEQKRTWMQELKRMMLDHYSVE-IPEKTKQLML 604
BLAST of DH domain-containing protein vs. Ensembl Celegans
Match: uig-1 (UNC-112-Interacting Guanine nucleotide exchange factor [Source:UniProtKB/TrEMBL;Acc:H1UBJ0]) HSP 1 Score: 114.39 bits (285), Expect = 2.685e-25 Identity = 103/341 (30.21%), Postives = 176/341 (51.61%), Query Frame = 2
Query: 737 ELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVELIFSNWRNL-RIFHSLFLEKLKLINSYEFSSLQ--RLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQ------SLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLL---KALDNMLQVANRINE--KQMXXXXXXXXXXXXXXXYDSD---IFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYI-PKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
EL++TE YV+ L V +GYM D + + +++++ +L +F +L N + + L ++S CF+E G FE Y EYCTNY HRM +T H Q +L + Q L H L LS +LLKPVQRILKYHL L+ +++ +H E L+ +A + M A RIN+ K+ E E++ +L+ + + +D I N G L+ + G + +RL+ L E L++ K+ G + + I C+ +ML E+I P++PL F V+ + + + + ++K W + +K++++ Y + I E+ K+++L
Sbjct: 263 ELLDTERTYVEDLNAVIKGYM---DFLVEDREKLKVTLDAISSLFGCIERIFAFNKQLYNQLDAADLDCVKMSRCFVESSGKFED-YIEYCTNY-------HRMMSTLYHLQQQPLVARALQERQLALNHSLQLSAYLLKPVQRILKYHLFLENILKNMPSTTH------PEELIQVKRAHEVMTSQAARINDEKKKAEHIERVGQLQSTLQKWKADEIQISNLSAYGDLLLEATFRQAGSKTTRLLFLFEEMLLIVKQRG-ANYVCKDYIMCSNLMLNEWICPEEPLSFQVLSFDNPRAQYVFMASSMEQKRTWMQELKRMMLDHYSVE-IPEKTKQLML 584
BLAST of DH domain-containing protein vs. Ensembl Fly
Match: GEFmeso (gene:FBgn0050115 transcript:FBtr0300421) HSP 1 Score: 129.798 bits (325), Expect = 1.160e-29 Identity = 102/330 (30.91%), Postives = 180/330 (54.55%), Query Frame = 2
Query: 737 ELVETEHIYVKSLMEVEEGYMK-MSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLD--GELKVPGC-----RNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRIL 1702
E+V++E +V+ L +V +GY++ + E++++F+N + F+S+ L++L IN+ R++ CF++ F+ +Y+ YCT+Y +++ L ++ A+H + L Q L H+LPL ++LLKPVQRILKYHL+L L + C + V A+ + M QVA+ I++ + ++E+Q R +L S I + +LG P L GEL+ G RLVLL L++ K+ +G+ + I N +ML E++P +P F+VI + +++ L N +K +W + IK +++ E I RAK ++
Sbjct: 548 EIVDSERSFVEDLGQVIKGYLQDWKERACLRVDELQILFANIEEIYEFNSMLLQRL--INTGRDPG--RIARCFIDLRDGFD-VYTTYCTSYPEAISLLTKL-LQATHTYSLLASTQKLLQHRLPLGSYLLKPVQRILKYHLLLDSLRKHCDVKEVVEAHVI----------MRQVAHNIDQVKRKQEQQSRVKEL------SGILDG-WLG-PELTVLGELRQEGLLMEQHNKQRLVLLFATMLIITKQKEDGRLQFKTYISQNNLMLSEHLPGEPTSFYVIPFDEPRHQIKLTARNRDQKRIWTQHIKGVML---EKLDIPMRAKELV 850
BLAST of DH domain-containing protein vs. Ensembl Fly
Match: GEFmeso (gene:FBgn0050115 transcript:FBtr0340387) HSP 1 Score: 129.413 bits (324), Expect = 1.241e-29 Identity = 102/330 (30.91%), Postives = 180/330 (54.55%), Query Frame = 2
Query: 737 ELVETEHIYVKSLMEVEEGYMK-MSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLD--GELKVPGC-----RNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRIL 1702
E+V++E +V+ L +V +GY++ + E++++F+N + F+S+ L++L IN+ R++ CF++ F+ +Y+ YCT+Y +++ L ++ A+H + L Q L H+LPL ++LLKPVQRILKYHL+L L + C + V A+ + M QVA+ I++ + ++E+Q R +L S I + +LG P L GEL+ G RLVLL L++ K+ +G+ + I N +ML E++P +P F+VI + +++ L N +K +W + IK +++ E I RAK ++
Sbjct: 236 EIVDSERSFVEDLGQVIKGYLQDWKERACLRVDELQILFANIEEIYEFNSMLLQRL--INTGRDPG--RIARCFIDLRDGFD-VYTTYCTSYPEAISLLTKL-LQATHTYSLLASTQKLLQHRLPLGSYLLKPVQRILKYHLLLDSLRKHCDVKEVVEAHVI----------MRQVAHNIDQVKRKQEQQSRVKEL------SGILDG-WLG-PELTVLGELRQEGLLMEQHNKQRLVLLFATMLIITKQKEDGRLQFKTYISQNNLMLSEHLPGEPTSFYVIPFDEPRHQIKLTARNRDQKRIWTQHIKGVML---EKLDIPMRAKELV 538
BLAST of DH domain-containing protein vs. Ensembl Fly
Match: GEFmeso (gene:FBgn0050115 transcript:FBtr0310055) HSP 1 Score: 127.872 bits (320), Expect = 2.174e-29 Identity = 101/330 (30.61%), Postives = 180/330 (54.55%), Query Frame = 2
Query: 737 ELVETEHIYVKSLMEVEEGYMK-MSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLD--GELKVPGC-----RNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRIL 1702
E+V++E +V+ L +V +GY++ + E++++F+N + F+S+ L++L IN+ R++ CF++ F+ +Y+ YCT+Y +++ L ++ A+H + L Q L H+LPL ++LLKPVQRILKYHL+L L + C + V A+ + M QVA+ I++ + ++E+Q R +L S I + +LG P L GEL+ G RLVLL L++ K+ +G+ + I N +ML E++P +P F+VI + +++ L N +K +W + IK +++ + I RAK ++
Sbjct: 548 EIVDSERSFVEDLGQVIKGYLQDWKERACLRVDELQILFANIEEIYEFNSMLLQRL--INTGRDPG--RIARCFIDLRDGFD-VYTTYCTSYPEAISLLTKL-LQATHTYSLLASTQKLLQHRLPLGSYLLKPVQRILKYHLLLDSLRKHCDVKEVVEAHVI----------MRQVAHNIDQVKRKQEQQSRVKEL------SGILDG-WLG-PELTVLGELRQEGLLMEQHNKQRLVLLFATMLIITKQKEDGRLQFKTYISQNNLMLSEHLPGEPTSFYVIPFDEPRHQIKLTARNRDQKRIWTQHIKGVMLEKLD---IPMRAKELV 850
BLAST of DH domain-containing protein vs. Ensembl Fly
Match: sif (gene:FBgn0085447 transcript:FBtr0340656) HSP 1 Score: 90.1225 bits (222), Expect = 1.597e-17 Identity = 74/243 (30.45%), Postives = 121/243 (49.79%), Query Frame = 2
Query: 599 FVFEKDKLLQSRPQATVKHIVNKFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMK-MSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKL-------INSYEFSSLQR-----LSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQT-QLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQ 1285
F + +S P +V V+ +L P+ L + EK V+ ELV+TE YVK L + E Y++ M F ++ E+ +F N + F FL+ L+ N +E R + FL + HF+ LYS +C +++++ K LH E +HA Q + + + H L ++L+KP+QRILKY L+L+++ + ++ A+ V L +AL M +VA INE Q
Sbjct: 1219 FCRSPQETRKSSPTGSVTSSVSTTALTPSRQL---TDAEKLRKVVMELVDTERTYVKHLNNLLEHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFLQNLEESLDLEPDFNKFEHCGQFRNVLFAIGSAFLYYVNHFK-LYSSFCASHSKAQKVLHPNE--GNHALQEFLAARNPKQQHSSTLESYLIKPIQRILKYPLLLQQM----RNLTDTRADEHVH-LCEALKGMEKVAEHINEMQ 1450
BLAST of DH domain-containing protein vs. Ensembl Fly
Match: sif (gene:FBgn0085447 transcript:FBtr0330123) HSP 1 Score: 90.1225 bits (222), Expect = 1.768e-17 Identity = 73/234 (31.20%), Postives = 119/234 (50.85%), Query Frame = 2
Query: 626 QSRPQATVKHIVNKFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMK-MSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKL-------INSYEFSSLQR-----LSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQT-QLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQ 1285
+S P +V V+ +L P+ L + EK V+ ELV+TE YVK L + E Y++ M F ++ E+ +F N + F FL+ L+ N +E R + FL + HF+ LYS +C +++++ K LH E +HA Q + + + H L ++L+KP+QRILKY L+L+++ + ++ A+ V L +AL M +VA INE Q
Sbjct: 1428 KSSPTGSVTSSVSTTALTPSRQL---TDAEKLRKVVMELVDTERTYVKHLNNLLEHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFLQNLEESLDLEPDFNKFEHCGQFRNVLFAIGSAFLYYVNHFK-LYSSFCASHSKAQKVLHPNE--GNHALQEFLAARNPKQQHSSTLESYLIKPIQRILKYPLLLQQM----RNLTDTRADEHVH-LCEALKGMEKVAEHINEMQ 1650
BLAST of DH domain-containing protein vs. Ensembl Zebrafish
Match: AL935335.1 (pleckstrin homology domain containing, family G (with RhoGef domain) member 2 [Source:NCBI gene;Acc:565988]) HSP 1 Score: 112.464 bits (280), Expect = 2.706e-24 Identity = 104/337 (30.86%), Postives = 168/337 (49.85%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKM---SDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQC----QTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHV-SANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLA-KRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLDN 1711
V E++ETE YV+ L + E Y+ + +EV +F N ++ F+S LE L+ ++ECF+E F+ +Y+ YC NY SV L +SL++ Q L H LPL T+LLKPVQRILKYHL+L+EL + H ++ E + A+ M VA IN+ + ++E +R ++ L + + G L+G +V + R L + L++A KRL + + I C ++L E + K PL F V D T K + +Q N +EK +W +K+LI+ ++ S+ ++A+++L DN
Sbjct: 135 VALEILETEQAYVRDLKSIVEDYLGCIIDCGDLPLKPEEVSTLFCNIEDIYEFNSELLEDLE-----RSPHAAAIAECFVERSEAFD-IYTIYCMNYPNSVTVLRDCMKN-----ESLVRFFQERQATLCHSLPLETYLLKPVQRILKYHLLLQELSK------HFDKSDPGYEVVEDAIITMTAVAWYINDMKRKQEHAIRLQEIESLLLNWTGPDLSGFGELVLEGSFRVQRVKKERAFFLFDKMLLIAKKRLDHFIYSTH--IFCCNLLLVENM-KDPLCFKVSDQTIPKQQHVVQAKNQEEKRLWLHYLKRLIVENHPA-SLPQKARQVLGDN 450
BLAST of DH domain-containing protein vs. Ensembl Zebrafish
Match: plekhg2 (pleckstrin homology domain containing, family G (with RhoGef domain) member 2 [Source:ZFIN;Acc:ZDB-GENE-090819-1]) HSP 1 Score: 112.464 bits (280), Expect = 3.254e-24 Identity = 104/337 (30.86%), Postives = 168/337 (49.85%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKM---SDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQC----QTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHV-SANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLA-KRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLDN 1711
V E++ETE YV+ L + E Y+ + +EV +F N ++ F+S LE L+ ++ECF+E F+ +Y+ YC NY SV L +SL++ Q L H LPL T+LLKPVQRILKYHL+L+EL + H ++ E + A+ M VA IN+ + ++E +R ++ L + + G L+G +V + R L + L++A KRL + + I C ++L E + K PL F V D T K + +Q N +EK +W +K+LI+ ++ S+ ++A+++L DN
Sbjct: 132 VALEILETEQAYVRDLKSIVEDYLGCIIDCGDLPLKPEEVSTLFCNIEDIYEFNSELLEDLE-----RSPHAAAIAECFVERSEAFD-IYTIYCMNYPNSVTVLRDCMKN-----ESLVRFFQERQATLCHSLPLETYLLKPVQRILKYHLLLQELSK------HFDKSDPGYEVVEDAIITMTAVAWYINDMKRKQEHAIRLQEIESLLLNWTGPDLSGFGELVLEGSFRVQRVKKERAFFLFDKMLLIAKKRLDHFIYSTH--IFCCNLLLVENM-KDPLCFKVSDQTIPKQQHVVQAKNQEEKRLWLHYLKRLIVENHPA-SLPQKARQVLGDN 447
BLAST of DH domain-containing protein vs. Ensembl Zebrafish
Match: mcf2b (MCF.2 cell line derived transforming sequence b [Source:ZFIN;Acc:ZDB-GENE-091118-4]) HSP 1 Score: 89.7373 bits (221), Expect = 1.719e-17 Identity = 72/214 (33.64%), Postives = 107/214 (50.00%), Query Frame = 2
Query: 668 FSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMKMSD---------SIFSNDKEVELIFSNWRNLRIFHS-LFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINE 1279
S P G N D + + VM+EL+ETE IYV+ LM V GY D S+ N KE +F N + FHS +FL+ L+ + +R+ FLE HF+ +Y YC N +S + +A + +C+ +L H+L L ++LLKPVQR+ KY L+LKEL++ H S + L AL+ ML + +N+
Sbjct: 495 LSYGPEGVENPDQHKRR---VMKELIETERIYVEELMSVLLGYRAEMDNPALSNILPSVLRNKKED--LFGNLPEIYKFHSRIFLQDLESC----LETPERVGARFLERKEHFQ-VYERYCQNKPRSDALWRQCSDSAF-----IQECKGKLDHKLGLDSYLLKPVQRLTKYQLLLKELLK------HSSNSQYASELQGALNAMLDLLKSVND 687
BLAST of DH domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01048666.1 (pep chromosome:GRCz11:23:2361184:2397031:1 gene:ENSDARG00000111585.1 transcript:ENSDART00000184469.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01048666.1) HSP 1 Score: 81.6481 bits (200), Expect = 1.694e-16 Identity = 53/149 (35.57%), Postives = 85/149 (57.05%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKMSDS---IFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLIL 1165
V++E++ETE YV+ L + + Y+ + + D+E +F N R++ F+S L L+ N+ + +++CF+ + F +Y++YCTNY +SV L A + L + Q L H LPL ++LLKPVQRILKYHL+L
Sbjct: 92 VVEEILETEKTYVQDLRSIVQDYLDCISNQSLLLLGDEERNSLFGNIRDIYRFNSELLRDLEKCNANPVA----IAKCFVAKSEDFH-IYTQYCTNYPRSVAVLTECMRNKMVA-KFLRERQESLKHSLPLGSYLLKPVQRILKYHLLL 234
BLAST of DH domain-containing protein vs. Ensembl Zebrafish
Match: mcf2lb (mcf.2 cell line derived transforming sequence-like b [Source:ZFIN;Acc:ZDB-GENE-081104-416]) HSP 1 Score: 83.1889 bits (204), Expect = 2.773e-16 Identity = 66/194 (34.02%), Postives = 102/194 (52.58%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKMSD---------SIFSNDKEVELIFSNWRNLRIFHS-LFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINE 1279
VM EL+ETE YV+ LM V +GY D + N K+V +F N + + FH +FL +L+ Y + + CFL+ +G + +Y +YC N +S + L R + + +CQ +L H+L L ++LLKPVQRI KY L++KE+I+ K G VE L AL ++L + +N+
Sbjct: 24 VMNELLETERAYVEELMCVLQGYAAEMDNPSMAPLIPAALQNKKDV--LFGNMQEIYNFHKRIFLRELETYTDYP----ELVGRCFLDWMGELQ-IYEKYCHNKPRS-ESLWRQCSDCAF----FQECQKKLEHKLGLDSYLLKPVQRITKYQLLIKEMIKYSK-----GCEGSVE-LQAALSSILGILKAVND 199
BLAST of DH domain-containing protein vs. Ensembl Xenopus
Match: tmem117 (transmembrane protein 117 [Source:Xenbase;Acc:XB-GENE-982355]) HSP 1 Score: 120.168 bits (300), Expect = 1.646e-26 Identity = 99/331 (29.91%), Postives = 176/331 (53.17%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMK-MSDS--IFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANG-VVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+QE++ TE YV+ L + E Y+ +SD + +E +F N ++ F+S L++L+ ++ + ++ECF+ + F +Y++YCTNY +SV L A + + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ + + +L A+D M +VA IN+ + + E +R +++ L + + G L+G + +N R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++ I +AK+ +L+
Sbjct: 165 VVQEILHTERAYVQDLKSIVEDYLNCISDQSRLSLGTEERSALFGNICDIYHFNSELLQELENCDNDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAILTECMRNKILA-KFFRERQEVLQHSLPLGSYLLKPVQRILKYHLLLHE------ISNHLDKDTEGYDIVLDAIDTMQRVAWHINDMKRKHEHDIRLQEIQSLLTNWKGPDLTSYGELVLEGTFRFQRAKNERTLFLFDRLLLITKKR-DDTYTYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWILHLKRLILENHP-AKIPAKAKQAILE 481
BLAST of DH domain-containing protein vs. Ensembl Xenopus
Match: tmem117 (transmembrane protein 117 [Source:Xenbase;Acc:XB-GENE-982355]) HSP 1 Score: 120.168 bits (300), Expect = 1.877e-26 Identity = 99/331 (29.91%), Postives = 176/331 (53.17%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMK-MSDS--IFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANG-VVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+QE++ TE YV+ L + E Y+ +SD + +E +F N ++ F+S L++L+ ++ + ++ECF+ + F +Y++YCTNY +SV L A + + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ + + +L A+D M +VA IN+ + + E +R +++ L + + G L+G + +N R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++ I +AK+ +L+
Sbjct: 178 VVQEILHTERAYVQDLKSIVEDYLNCISDQSRLSLGTEERSALFGNICDIYHFNSELLQELENCDNDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAILTECMRNKILA-KFFRERQEVLQHSLPLGSYLLKPVQRILKYHLLLHE------ISNHLDKDTEGYDIVLDAIDTMQRVAWHINDMKRKHEHDIRLQEIQSLLTNWKGPDLTSYGELVLEGTFRFQRAKNERTLFLFDRLLLITKKR-DDTYTYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWILHLKRLILENHP-AKIPAKAKQAILE 494
BLAST of DH domain-containing protein vs. Ensembl Xenopus
Match: tmem117 (transmembrane protein 117 [Source:Xenbase;Acc:XB-GENE-982355]) HSP 1 Score: 117.857 bits (294), Expect = 7.409e-26 Identity = 95/316 (30.06%), Postives = 168/316 (53.16%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMK-MSDS--IFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANG-VVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSY 1663
V+QE++ TE YV+ L + E Y+ +SD + +E +F N ++ F+S L++L+ ++ + ++ECF+ + F +Y++YCTNY +SV L A + + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ + + +L A+D M +VA IN+ + + E +R +++ L + + G L+G + +N R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++
Sbjct: 122 VVQEILHTERAYVQDLKSIVEDYLNCISDQSRLSLGTEERSALFGNICDIYHFNSELLQELENCDNDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAILTECMRNKILA-KFFRERQEVLQHSLPLGSYLLKPVQRILKYHLLLHE------ISNHLDKDTEGYDIVLDAIDTMQRVAWHINDMKRKHEHDIRLQEIQSLLTNWKGPDLTSYGELVLEGTFRFQRAKNERTLFLFDRLLLITKK-RDDTYTYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWILHLKRLILENH 424
BLAST of DH domain-containing protein vs. Ensembl Xenopus
Match: tmem117 (transmembrane protein 117 [Source:Xenbase;Acc:XB-GENE-982355]) HSP 1 Score: 117.857 bits (294), Expect = 7.755e-26 Identity = 101/330 (30.61%), Postives = 173/330 (52.42%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMK-MSDS--IFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANG-VVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
V+QE++ TE YV+ L + E Y+ +SD + +E +F N ++ F+S L++L+ ++ + ++ECF+ + F +Y++YCTNY +SV L A + + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ + + +L A+D M +VA IN+ + + E +R +++ L + + G L+G + +N R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ E+ AK ILL
Sbjct: 26 VVQEILHTERAYVQDLKSIVEDYLNCISDQSRLSLGTEERSALFGNICDIYHFNSELLQELENCDNDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAILTECMRNKILA-KFFRERQEVLQHSLPLGSYLLKPVQRILKYHLLLHE------ISNHLDKDTEGYDIVLDAIDTMQRVAWHINDMKRKHEHDIRLQEIQSLLTNWKGPDLTSYGELVLEGTFRFQRAKNERTLFLFDRLLLITKK-RDDTYTYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWILHLKRLIL---ENHPAKIPAKVILL 339
BLAST of DH domain-containing protein vs. Ensembl Xenopus
Match: tmem117 (transmembrane protein 117 [Source:Xenbase;Acc:XB-GENE-982355]) HSP 1 Score: 117.472 bits (293), Expect = 9.965e-26 Identity = 101/330 (30.61%), Postives = 173/330 (52.42%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMK-MSDS--IFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANG-VVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
V+QE++ TE YV+ L + E Y+ +SD + +E +F N ++ F+S L++L+ ++ + ++ECF+ + F +Y++YCTNY +SV L A + + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ + + +L A+D M +VA IN+ + + E +R +++ L + + G L+G + +N R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ E+ AK ILL
Sbjct: 122 VVQEILHTERAYVQDLKSIVEDYLNCISDQSRLSLGTEERSALFGNICDIYHFNSELLQELENCDNDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAILTECMRNKILA-KFFRERQEVLQHSLPLGSYLLKPVQRILKYHLLLHE------ISNHLDKDTEGYDIVLDAIDTMQRVAWHINDMKRKHEHDIRLQEIQSLLTNWKGPDLTSYGELVLEGTFRFQRAKNERTLFLFDRLLLITKKR-DDTYTYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWILHLKRLIL---ENHPAKIPAKVILL 435
BLAST of DH domain-containing protein vs. Ensembl Mouse
Match: Plekhg1 (pleckstrin homology domain containing, family G (with RhoGef domain) member 1 [Source:MGI Symbol;Acc:MGI:2676551]) HSP 1 Score: 118.242 bits (295), Expect = 4.991e-26 Identity = 96/319 (30.09%), Postives = 171/319 (53.61%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMK-MSD----SIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLI-QCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVS-ANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSY 1663
V+QE++ETE YV+ L + EGY++ + D + + D+ +F N +++ F+S L+ L+ + + ++ECF+ + F +Y++YCTNY +SV L E + + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ A + +L A+D M +VA IN+ + + E +R +++ L + + + G L+G ++ + R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++
Sbjct: 116 VVQEILETERTYVQDLKSIVEGYLECIRDQTKLPLVTEDRAA--LFGNIQDIYHFNSELLQDLENCENDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAVL--TECMRNKILTKFFRERQETLRHSLPLGSYLLKPVQRILKYHLLLHE------IENHLDKATEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWEGPDLTSYGELVLEGTFRIQKAKKERTLFLLDQLLLITKKR-DDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENH 418
BLAST of DH domain-containing protein vs. Ensembl Mouse
Match: Plekhg1 (pleckstrin homology domain containing, family G (with RhoGef domain) member 1 [Source:MGI Symbol;Acc:MGI:2676551]) HSP 1 Score: 118.242 bits (295), Expect = 4.991e-26 Identity = 96/319 (30.09%), Postives = 171/319 (53.61%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMK-MSD----SIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLI-QCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVS-ANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSY 1663
V+QE++ETE YV+ L + EGY++ + D + + D+ +F N +++ F+S L+ L+ + + ++ECF+ + F +Y++YCTNY +SV L E + + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ A + +L A+D M +VA IN+ + + E +R +++ L + + + G L+G ++ + R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++
Sbjct: 116 VVQEILETERTYVQDLKSIVEGYLECIRDQTKLPLVTEDRAA--LFGNIQDIYHFNSELLQDLENCENDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAVL--TECMRNKILTKFFRERQETLRHSLPLGSYLLKPVQRILKYHLLLHE------IENHLDKATEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWEGPDLTSYGELVLEGTFRIQKAKKERTLFLLDQLLLITKKR-DDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENH 418
BLAST of DH domain-containing protein vs. Ensembl Mouse
Match: Plekhg1 (pleckstrin homology domain containing, family G (with RhoGef domain) member 1 [Source:MGI Symbol;Acc:MGI:2676551]) HSP 1 Score: 117.857 bits (294), Expect = 5.848e-26 Identity = 96/319 (30.09%), Postives = 171/319 (53.61%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMK-MSD----SIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLI-QCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVS-ANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSY 1663
V+QE++ETE YV+ L + EGY++ + D + + D+ +F N +++ F+S L+ L+ + + ++ECF+ + F +Y++YCTNY +SV L E + + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ A + +L A+D M +VA IN+ + + E +R +++ L + + + G L+G ++ + R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++
Sbjct: 172 VVQEILETERTYVQDLKSIVEGYLECIRDQTKLPLVTEDRAA--LFGNIQDIYHFNSELLQDLENCENDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAVL--TECMRNKILTKFFRERQETLRHSLPLGSYLLKPVQRILKYHLLLHE------IENHLDKATEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWEGPDLTSYGELVLEGTFRIQKAKKERTLFLLDQLLLITKKR-DDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENH 474
BLAST of DH domain-containing protein vs. Ensembl Mouse
Match: Plekhg1 (pleckstrin homology domain containing, family G (with RhoGef domain) member 1 [Source:MGI Symbol;Acc:MGI:2676551]) HSP 1 Score: 117.857 bits (294), Expect = 5.991e-26 Identity = 96/319 (30.09%), Postives = 171/319 (53.61%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMK-MSD----SIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLI-QCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVS-ANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSY 1663
V+QE++ETE YV+ L + EGY++ + D + + D+ +F N +++ F+S L+ L+ + + ++ECF+ + F +Y++YCTNY +SV L E + + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ A + +L A+D M +VA IN+ + + E +R +++ L + + + G L+G ++ + R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++
Sbjct: 191 VVQEILETERTYVQDLKSIVEGYLECIRDQTKLPLVTEDRAA--LFGNIQDIYHFNSELLQDLENCENDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAVL--TECMRNKILTKFFRERQETLRHSLPLGSYLLKPVQRILKYHLLLHE------IENHLDKATEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWEGPDLTSYGELVLEGTFRIQKAKKERTLFLLDQLLLITKKR-DDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENH 493
BLAST of DH domain-containing protein vs. Ensembl Mouse
Match: Plekhg3 (pleckstrin homology domain containing, family G (with RhoGef domain) member 3 [Source:MGI Symbol;Acc:MGI:2388284]) HSP 1 Score: 115.931 bits (289), Expect = 2.569e-25 Identity = 111/400 (27.75%), Postives = 193/400 (48.25%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYM-KMSDSI-FSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL--DNKHNVLSQCQPISNDVLEKFQVTLNRENDVLDLESSLRKMFDP----VSTQSSQSKHKSIKRRNSVGAI 1903
V++E+VETE +YV+ L + E Y+ K+ D+ ++V +F N ++ +S L L NS + ++ CF+E F+ +Y++YC NY SV L A + Q L H LPL ++LLKPVQR+LKYHL+L+E+ + VVE A+D M VA IN+ + E +R +++ L + + G L+ +V RN R L + L++ K+ G+ + + I C+ +ML E + L F V +K + ++Q +EK W IK+LI+ ++ H +I ++AK +L D+ + +C P E+ + + +++V R+ +P + S +++ +K S GA+
Sbjct: 97 VVREIVETERMYVQDLRSIVEDYLLKIIDTPGLLKPEQVSALFGNIESIYALNSQLLRDLDSCNSDPVA----VASCFVERSQEFD-IYTQYCNNYPNSVAALTECMQDKQQA-KFFRDRQELLQHSLPLGSYLLKPVQRVLKYHLLLQEIAK--HFDEEEDGFEVVED---AIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTYGELVLEATFRVHRVRNDRTFFLFDKILLITKKRGD-HFVYKGHIPCSSLMLIEST-RDSLCFTVTHYKHSKQQYSIQAKTVEEKRSWTHHIKRLILENH-HATIPQKAKEAILEMDSYYPSRYRCSP------ERMKKAWSSQDEVSSHVRQGRRQSEPTRHLLRQLSEKARAVGMKHAGSAGAL 476
BLAST of DH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9ULL1|PKHG1_HUMAN (Pleckstrin homology domain-containing family G member 1 OS=Homo sapiens OX=9606 GN=PLEKHG1 PE=1 SV=2) HSP 1 Score: 125.946 bits (315), Expect = 1.563e-27 Identity = 103/333 (30.93%), Postives = 172/333 (51.65%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDK------EVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+QE++ETE YV+ L + E Y+ D I K E +F N +++ F+S L+ L+ + + ++ECF+ + F +Y++YCTNY +SV L A + + Q L H LPL ++LLKPVQRILKYHL+L E+ L VV L A+D M +VA IN+ + + E +R +++ L + + G L+G ++ +N R + L + L++ K+ + + + I C +ML E IPK+PL F V + K + T+Q + Q+K +W +K+LI+ ++ I +AK+ +L+
Sbjct: 117 VVQEILETERTYVQDLKSIVEDYL---DCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVA----IAECFVSKSEEFH-IYTQYCTNYPRSVAVLTECMRNKILA-KFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIEN--HLDKDTEGYDVV---LDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKR-DDTFTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAA-KIPAKAKQAILE 433
BLAST of DH domain-containing protein vs. UniProt/SwissProt
Match: sp|A1L390|PKHG3_HUMAN (Pleckstrin homology domain-containing family G member 3 OS=Homo sapiens OX=9606 GN=PLEKHG3 PE=1 SV=1) HSP 1 Score: 119.783 bits (299), Expect = 9.579e-26 Identity = 102/329 (31.00%), Postives = 166/329 (50.46%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYM-KMSDSI-FSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V++E+VETE +YV+ L + E Y+ K+ D+ ++V +F N N+ +S L L NS + ++ CF+E F+ +Y++YC NY SV L A + Q L H LPL ++LLKPVQRILKYHL+L+E+ + VVE A+D M VA IN+ + E +R +++ L + + G L+G +V RN R L + L++ K+ G+ + + I C+ +ML E + L F V +K + ++Q +EK W IK+LI+ ++ H +I ++AK +L+
Sbjct: 97 VVREIVETERMYVQDLRSIVEDYLLKIIDTPGLLKPEQVSALFGNIENIYALNSQLLRDLDSCNSDPVA----VASCFVERSQEFD-IYTQYCNNYPNSVAALTECMRDKQQA-KFFRDRQELLQHSLPLGSYLLKPVQRILKYHLLLQEIAK--HFDEEEDGFEVVED---AIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTYGELVLEGTFRVHRVRNERTFFLFDKTLLITKKRGD-HFVYKGNIPCSSLMLIEST-RDSLCFTVTHYKHSKQQYSIQAKTVEEKRNWTHHIKRLILENH-HATIPQKAKEAILE 411
BLAST of DH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4VAC9|PKHG3_MOUSE (Pleckstrin homology domain-containing family G member 3 OS=Mus musculus OX=10090 GN=Plekhg3 PE=1 SV=2) HSP 1 Score: 115.546 bits (288), Expect = 2.419e-24 Identity = 102/342 (29.82%), Postives = 170/342 (49.71%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYM-KMSDSI-FSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL--DNKHNVLSQCQP 1741
V++E+VETE +YV+ L + E Y+ K+ D+ ++V +F N ++ +S L L NS + ++ CF+E F+ +Y++YC NY SV L A + Q L H LPL ++LLKPVQR+LKYHL+L+E+ + VVE A+D M VA IN+ + E +R +++ L + + G L+ +V RN R L + L++ K+ G+ + + I C+ +ML E + L F V +K + ++Q +EK W IK+LI+ ++ H +I ++AK +L D+ + +C P
Sbjct: 97 VVREIVETERMYVQDLRSIVEDYLLKIIDTPGLLKPEQVSALFGNIESIYALNSQLLRDLDSCNSDPVA----VASCFVERSQEFD-IYTQYCNNYPNSVAALTECMQDKQQA-KFFRDRQELLQHSLPLGSYLLKPVQRVLKYHLLLQEIAK--HFDEEEDGFEVVED---AIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTYGELVLEATFRVHRVRNDRTFFLFDKILLITKKRGD-HFVYKGHIPCSSLMLIEST-RDSLCFTVTHYKHSKQQYSIQAKTVEEKRSWTHHIKRLILENH-HATIPQKAKEAILEMDSYYPSRYRCSP 424
BLAST of DH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6KAU7|PKHG2_MOUSE (Pleckstrin homology domain-containing family G member 2 OS=Mus musculus OX=10090 GN=Plekhg2 PE=2 SV=2) HSP 1 Score: 100.908 bits (250), Expect = 6.939e-20 Identity = 74/221 (33.48%), Postives = 117/221 (52.94%), Query Frame = 2
Query: 629 SRPQATVKHIVNKFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMKM---SDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHA-WQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINE 1279
SRP+ + + + L P G + ++ + V +E+VETE YV+ L + E Y+ ++ N ++V +F+N ++ F S LE L+ SS ++ECF++ F+ +Y+ YC NY S+ L + + W L + Q QL H LPL +FLLKPVQRILKYHL+L+EL K + +G E + +A+ +M VA IN+
Sbjct: 71 SRPEPLPEPPI-RLHLLPVG-IQGSVKPSRLERVAREIVETERAYVRDLRSIVEDYLGPLMDGRALGLNMEQVGTLFANIEDIYEFSSELLEDLE-----GCSSAGGIAECFVQRSEDFD-IYTLYCMNYPSSLALLRELSVSPPATLW--LQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQEL---GKHWAEGPDSGGREMVEEAIVSMTAVAWYIND 278
BLAST of DH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9H7P9|PKHG2_HUMAN (Pleckstrin homology domain-containing family G member 2 OS=Homo sapiens OX=9606 GN=PLEKHG2 PE=1 SV=3) HSP 1 Score: 99.7525 bits (247), Expect = 1.423e-19 Identity = 76/221 (34.39%), Postives = 116/221 (52.49%), Query Frame = 2
Query: 629 SRPQATVKHIVNKFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMK--MSDSIFS-NDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHA-WQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINE 1279
SRP+ + + L P G + + V +E+VETE YV+ L + E Y+ + + + ++V +F+N ++ F S LE L+ NS SS ++ECF++ F+ +Y+ YC NY S+ L + + A W L + Q QL H LPL +FLLKPVQRILKYHL+L+EL K + G E + +A+ +M VA IN+
Sbjct: 75 SRPEPLPGPPI-RLHLSPVG-IPGSARPSRLERVAREIVETERAYVRDLRSIVEDYLGPLLDGGVLGLSVEQVGTLFANIEDIYEFSSELLEDLE--NS---SSAGGIAECFVQRSEDFD-IYTLYCMNYPSSLALLRELSLSPPAALW--LQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQEL---GKHWAEGPGTGGREMVEEAIVSMTAVAWYIND 282
BLAST of DH domain-containing protein vs. TrEMBL
Match: A0A158QF70 (DH domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS8434 PE=4 SV=1) HSP 1 Score: 191.045 bits (484), Expect = 1.180e-46 Identity = 135/402 (33.58%), Postives = 210/402 (52.24%), Query Frame = 2
Query: 593 QCFVFEKDKLLQSRPQATVKHIVNKFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKE-VELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMS----HVSANG----VVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNS-RLVLLCENALVLAKRL------------------GNGKWGV---RQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
Q F + L Q RP + + ++ P+ + S + +K V+ EL++TE Y+ SL +++EGY + ++ D ++ IFSN + FH F +L L +L L+ FL+ FE LY E+CT ++ S++ L S W S+++CQ+QLGH LPL+++LLKPVQRILKY L+ +EL++ C L H NG V+ L AL M+QVAN INE + +LR D D + G L ++P +++ RLVLL E A++LAK+ G G V R +I CN +ML E I K PL FH++ + + TLQ +NA+ K +WC+ IK++I+ +++ +I E+AK ++L
Sbjct: 4 QQLKFSEHPLDQLRPSSGRSYPCSR---TPDSSKGSRVALKKVAWVIGELLDTEIAYLDSLRDIKEGYYQPLLALNKFDTSTLDTIFSNVVQIHAFHQNFSGELSL----NQENLIGLANVFLDHAADFEELYVEFCTEHSLSIQTLEHESQIQSELWTSILECQSQLGHLLPLASYLLKPVQRILKYQLLFQELVKACTLAGLDQNHSIFNGDPTTTVDHLQSALQRMVQVANHINEAK---RHHDLISQLRAGGLDVDQW-----GRLLLRDVFRLPAKKHACRLVLLFERAILLAKKFSYAGNNSTPNLTDLQSNSGEGLQSVLEIRDIISCNNLMLIECIDKDPLAFHILPFNNPNAQKTLQAVNAEVKHLWCREIKRVILENFD-AAIPEKAKHLML 389
BLAST of DH domain-containing protein vs. TrEMBL
Match: A0A068Y0P7 (DH domain containing protein OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000533900 PE=4 SV=1) HSP 1 Score: 189.119 bits (479), Expect = 4.351e-45 Identity = 123/385 (31.95%), Postives = 206/385 (53.51%), Query Frame = 2
Query: 644 TVKHIVNKFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMK--MSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMS--------HVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNS-RLVLLCENALVLAKRLGNGK--------------------WGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
+++H+ P+ + + + +K V+ EL+ETE Y++SL +++EGY +++ F + ++ +F+N L FH F +L ++L L++ FLE FE LY E+CT ++ S++ L + W S++ CQT+LGH LPL+++LLKPVQR+LKY L+L+ELI+ C L + N +V+ L AL+ M+QVA INE + +LR +D D + C L + ++P +++ RLVLL E A++LAK+ G +R +I CN +ML E I K PL FH++ + + TLQ +A K +WC+ IK++I+ +++ +I E+AK ++L
Sbjct: 12 SLEHLRPSSGRSPDSSAEACVSLKKVAWVISELLETELTYLESLRDIKEGYYLPLLAEGKF-DATTLDTVFNNIIQLHAFHQTFSGELY----RNQANLAGLADVFLEHAVDFEGLYVEFCTEHSLSIQTLEHESLLHTELWASILACQTRLGHLLPLASYLLKPVQRVLKYQLLLQELIKGCTLAGLGQNQRILNGDPNFIVKHLQSALERMIQVATHINEAK---RRHELIGQLRASGFDVDQWGCLLLRDVF-----RLPAKKHACRLVLLFERAILLAKKFYAGNNSAPNLKDLQSSSGEELQSVLEIRDIISCNNLMLIECIDKDPLAFHILPFNNPNAQKTLQAASADVKHLWCREIKRVILENFDA-AIPEKAKHLML 382
BLAST of DH domain-containing protein vs. TrEMBL
Match: A0A068WMG8 (DH domain containing protein OS=Echinococcus granulosus OX=6210 GN=EgrG_000533900 PE=4 SV=1) HSP 1 Score: 188.348 bits (477), Expect = 9.688e-45 Identity = 126/380 (33.16%), Postives = 203/380 (53.42%), Query Frame = 2
Query: 659 VNKFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMK--MSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMS--------HVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNS-RLVLLCENALVLAKRL-----------------GNGKWGV---RQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
V S P+ + + + +K V+ EL+ETE Y++SL +++EGY +++ F + ++ +F+N L FH F +L +L L++ FLE FE LY E+CT ++ S++ L + W S++ CQT+LGH LPL+++LLKPVQR+LKY L+L+EL++ C L + N VV+ L AL+ M+QVA INE + +LR +D D + C L + ++P +++ RLVLL E A++LAK+ G G V R +I CN +ML E I K PL FH++ + + TLQ +A K +WC+ IK++I+ +++ +I E+AK ++L
Sbjct: 23 VYSHSRSPDSSAEARVSLKKVAWVISELLETELTYLESLRDIKEGYYLPLLAEGKF-DATTLDTVFNNIIQLHAFHQTFSGELY----RNQENLVGLADVFLEHAVDFEGLYVEFCTEHSLSIQTLEHESLLHTELWASILACQTRLGHLLPLASYLLKPVQRVLKYQLLLQELVKGCTLAGLGQNQSIFNGDPNFVVKHLQSALERMIQVATHINEAK---RRHELIGQLRASGFDVDQWGCLLLRDVF-----RLPAKKHACRLVLLFERAILLAKKFYAGNNSAPNLKDLQSSSGEGLQSVLEIRDIISCNNLMLIECIDKDPLAFHILPFNNPNAQKTLQAASADVKHLWCREIKRVILENFD-AAIPEKAKHLML 388
BLAST of DH domain-containing protein vs. TrEMBL
Match: A0A158RFB3 (DH domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS9396 PE=4 SV=1) HSP 1 Score: 186.422 bits (472), Expect = 4.226e-44 Identity = 125/380 (32.89%), Postives = 202/380 (53.16%), Query Frame = 2
Query: 659 VNKFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMK--MSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMS--------HVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNS-RLVLLCENALVLAKRL-----------------GNGKWGV---RQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILL 1705
V S P+ + + +K V+ EL+ETE Y++SL +++EGY +++ F + ++++FSN L FH +F +L L L++ FLE FE LY E+CT ++ S++ L S W S++ CQ++LGH LPL+++LLKPVQR+LKY L+L+EL++ L + N VV+ L AL+ M+QVA INE + +LR D D + C L + ++P +++ RLVLL E A++LAK+ G G V R +I CN +ML E I K PL FH++ + + TLQ + + K++WC+ IK++I+ +++ +I E+AK ++L
Sbjct: 23 VYSHSHSPDSLTEARVALKKVAWVISELLETEVAYLESLRDIKEGYYLPLIAEGKF-DATTLDIVFSNITQLHAFHQIFSNELY----RNRDDLVGLADVFLERATDFEGLYVEFCTEHSLSIQTLEHESHLQSELWASILACQSRLGHLLPLASYLLKPVQRVLKYQLLLQELVKGYTLAGLGQNQSIFNGDPNSVVKHLQSALERMIQVATHINEAK---RRHELIGQLRASGLDVDQWGCLLLRDVF-----RLPAKKHACRLVLLFERAILLAKKFSYAGNNSAPNLKDLQSPGEGSQSVLEIRDIISCNNLMLIECIDKDPLAFHILPFNNPNAQKTLQAASTEVKQLWCREIKRVILENFDA-AIPEKAKHLML 388
BLAST of DH domain-containing protein vs. TrEMBL
Match: A0A504YC62 (Putative transcript OS=Fasciola gigantica OX=46835 GN=FGIG_02055 PE=4 SV=1) HSP 1 Score: 174.481 bits (441), Expect = 5.951e-41 Identity = 129/414 (31.16%), Postives = 192/414 (46.38%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVE-----LIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSA----------------------------------NGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWG------------------------------------------------VRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+ EL+ETE YV+SL +V++GY+ D +VE +F +LRIFH L L+L L +L+ FL FE LY E+C NY++S+ L + + W L CQ LGHQLP+ T+LLKPVQR+LKY L+L+E ++ C MS + A N V L +AL+ M++VA+ INEK+ RE + +R ++ D G L G +VPG ++ RLVLL A++L K G+ + G +R++I C +ML E IPK L FH++ + K + TLQ + K +WC+ IK+LI+ +Y+ +I E+AK I+L+
Sbjct: 42 VIGELIETEKNYVQSLFDVDQGYLAQ----LLQDPDVESSVLDTVFGRIGDLRIFHEHLLLNLQL----HREDLVQLARVFLNNAKQFEHLYVEFCINYSKSIHTLQDAKQNRTSLWNKLTTCQRNLGHQLPVETYLLKPVQRVLKYQLLLQECVKHC--MSAIHALNRSGEAPTDTNRAVPSSHGLDLTDSRISLLHHLNEAVPVLGQALERMIKVADHINEKKRCRELIDQLRTMRIDVDD--------WGELVLRGYFRVPGKKDLRLVLLFHRAILLCKNSGSTQSGQSGTFSASGSADQLWSASTSTIHNTEFGFSNSSLPNLGGHASGSRTVQIREIINCANLMLVECIPKDALAFHILPFDNPKAQRTLQAPTLEMKRLWCREIKRLILENYD-AAIPEKAKHIVLN 436
BLAST of DH domain-containing protein vs. Ensembl Cavefish
Match: PLEKHG1 (pleckstrin homology and RhoGEF domain containing G1 [Source:HGNC Symbol;Acc:HGNC:20884]) HSP 1 Score: 124.405 bits (311), Expect = 5.459e-28 Identity = 99/321 (30.84%), Postives = 167/321 (52.02%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVEL-------IFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHR-METTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVV-ESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSY 1663
V+QE++ETE YV+ L + + Y++ SN L +F N R + F+ L L+ N+ + ++ECF+ + F +Y++YCTNY +SV L M A + L + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ + + E + +A+D M +VA IN+ + + E +R +++ L + + G L+G +V +N R + L + L++ K+ + + I C +ML E IPK+PL F V + K + T+Q + Q+K W + +K+LI+ ++
Sbjct: 88 VVQEILETERTYVQDLRSIVQDYLE----CISNQARPLLGVEDRNSLFGNIREIYGFNRDLLHDLEKCNANPVA----IAECFVAKSEEFH-IYTQYCTNYPRSVAVLSECMRNKAVAKF--LRERQESLKHSLPLGSYLLKPVQRILKYHLLLHE------IATHLEKDSEMHEVVQEAIDTMQRVAWHINDMKRKHENTIRLQEIQSLLTNWQGPDLIGYGELVLEGTFRVQRVKNERTLFLFDKLLLITKKR-EETYTYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRTWIQHLKRLILENH 390
BLAST of DH domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000043929.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:1805767:1835459:1 gene:ENSAMXG00000040969.1 transcript:ENSAMXT00000043929.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 104.375 bits (259), Expect = 5.255e-22 Identity = 91/291 (31.27%), Postives = 147/291 (50.52%), Query Frame = 2
Query: 845 IFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLH---RMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
+F N + F+S L+ L+L +S + ++ CF+++ +F +Y++YCTNY SV L R +T A + Q L LPL +LLKPVQRILKYHL+L+E+ + VVE +A+D M VA IN+ + + E +R+ +++ L + + G L+G V +N R + L + L++ K+ G + + I C+ +ML E K L F V K T+Q +EK++W IK+LI+ ++ H I + AK +LD
Sbjct: 72 LFGNIEVIYEFNSELLQSLELCDSDPVA----IACCFVDKSEYFN-IYTQYCTNYPNSVATLTECMRNKTLA----KFFRDRQASLERSLPLGAYLLKPVQRILKYHLLLQEIAK--HFDPEEDGYDVVE---EAIDTMTGVAWYINDMKRKHEHAVRQQEIQSLLINWKGPDLTTYGELVLEGTFHVQRAKNERTLFLFDKMLLITKKRGE-HYVYKTHITCSTLMLIESA-KDLLRFSVTHYKHPKQPHTVQAKTVEEKKLWAHHIKRLILENH-HAVIPQTAKNAILD 345
BLAST of DH domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000055531.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:1805767:1835459:1 gene:ENSAMXG00000040969.1 transcript:ENSAMXT00000055531.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 104.375 bits (259), Expect = 5.617e-22 Identity = 91/291 (31.27%), Postives = 147/291 (50.52%), Query Frame = 2
Query: 845 IFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLH---RMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
+F N + F+S L+ L+L +S + ++ CF+++ +F +Y++YCTNY SV L R +T A + Q L LPL +LLKPVQRILKYHL+L+E+ + VVE +A+D M VA IN+ + + E +R+ +++ L + + G L+G V +N R + L + L++ K+ G + + I C+ +ML E K L F V K T+Q +EK++W IK+LI+ ++ H I + AK +LD
Sbjct: 72 LFGNIEVIYEFNSELLQSLELCDSDPVA----IACCFVDKSEYFN-IYTQYCTNYPNSVATLTECMRNKTLA----KFFRDRQASLERSLPLGAYLLKPVQRILKYHLLLQEIAK--HFDPEEDGYDVVE---EAIDTMTGVAWYINDMKRKHEHAVRQQEIQSLLINWKGPDLTTYGELVLEGTFHVQRAKNERTLFLFDKMLLITKKRGE-HYVYKTHITCSTLMLIESA-KDLLRFSVTHYKHPKQPHTVQAKTVEEKKLWAHHIKRLILENH-HAVIPQTAKNAILD 345
BLAST of DH domain-containing protein vs. Ensembl Cavefish
Match: plekhg2 (pleckstrin homology domain containing, family G (with RhoGef domain) member 2 [Source:ZFIN;Acc:ZDB-GENE-090819-1]) HSP 1 Score: 100.523 bits (249), Expect = 1.069e-20 Identity = 106/358 (29.61%), Postives = 172/358 (48.04%), Query Frame = 2
Query: 659 VNKFSLCPNGNLNSDIER-EKWHLVMQELVETEHIYVKSLMEVEEGYMKM---SDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQ-CQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHV-SANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLA-KRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLDN 1711
+ SL P ++ + + + V E+VETE YV+ L + E Y+ + +EV +F N ++ F+S LE L+ S ++ECF+E F+ +Y+ YC NY SV L + + Q Q L H LPL T+LLKPVQRILKYHL+L+EL + H ++ E + A+ M VA IN+ + ++E +R ++ L + + G L+G +V + R L + L++A KRL + + I C ++L E + K PL F V D T K + +Q+ E+ K IK LI+ ++ S+ ++A+++L D
Sbjct: 103 LTPLSLLPGATPSTPLPKLSRLQRVALEIVETEQAYVRDLKSIVEDYLGCIIDCGDLPLKPEEVSTLFCNIEDIYEFNSDLLEDLE-----RSSHAAAIAECFVERSEAFD-IYTIYCMNYPNSVAVLR--DCMKNECLVRFFQERQATLCHSLPLETYLLKPVQRILKYHLLLQELSK------HFDKSDPGYEVVEDAIITMTAVAWYINDMKRKQEHAVRLQEIESLLLNWTGPDLSGFGELVLEGSFRVQRVKKERAFFLFDKMLLIAKKRLDHFIYSTH--IFCCNLLLVENM-KDPLCFKVSDQTIPKQQHIVQIT---ERMCHLKHIKILIVENHPA-SLPQKARQVLGDT 439
BLAST of DH domain-containing protein vs. Ensembl Cavefish
Match: mcf2l2 (MCF.2 cell line derived transforming sequence-like 2 [Source:ZFIN;Acc:ZDB-GENE-100812-1]) HSP 1 Score: 85.5001 bits (210), Expect = 3.537e-16 Identity = 79/266 (29.70%), Postives = 126/266 (47.37%), Query Frame = 2
Query: 530 HSAVVKSHLKDSGTSSLNDEDQCF-VFEKDKLLQSRPQATVKHIVNKFSLCPNGNL---NSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMKMSD---------SIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLI--QCQTQLGHQLPLSTFLLKPVQRILKYHLILK-ELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINE 1279
H ++ H+K + S+L D+ +FEK + R A V + P + + R +M EL+E+E YV+ L + EGY+ D ++ N K+V +F N + FH+ FL++L+ N E L + CFL+ + +Y +YC N +S E S+ +CQ +L H+L L +LLKPVQRI KY L+LK E+++C K ++ G E L +AL ML + +N+
Sbjct: 486 HEIILSDHIKINVQSALKRLDEVQEMFEKRHISLKRLSAKQSRPVQPVAPRPESSPKRPSPKTPRPSGPHIMNELIESERYYVEELQSIMEGYVAALDNSEMTHLIPAVLENKKDV--LFGNLGEIWDFHNTFLKELE--NYVEKPEL--VGTCFLKRKEELQ-IYEKYCQNKPRS-------EALWRQCGDSMFFQECQKRLDHKLSLDAYLLKPVQRITKYQLMLKQEMLKCSK-----NSEGTAE-LEEALATMLDIIKSVND 731
BLAST of DH domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008020.1 (pep scaffold:Pmarinus_7.0:GL476484:132482:154779:-1 gene:ENSPMAG00000007248.1 transcript:ENSPMAT00000008020.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 135.961 bits (341), Expect = 4.776e-35 Identity = 108/327 (33.03%), Postives = 182/327 (55.66%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+ E+++TE +YV+ L + E Y++ ND +V +F N + + F+S LE+L+ ++ + ++ECF+E+ G FE +Y++YCTN+ S++ L + T S A + Q L H LPL +FLLKPVQRILKYHL+L+E+ + +L VV+ AL M VA INE + + E +R +LR L + + LG L+G ++ R R + L +++L++ K+ +G + + IKC +M+ E P++ LEF V + K + T Q +EK W IK+LI+ ++ ++ ++AK I+L+
Sbjct: 13 VVLEILDTERMYVRHLKSIVEDYLRAISQRLPND-DVNTLFGNIKEIYKFNSELLEELEDCSNDPVA----IAECFVEKSGGFE-IYTQYCTNFPSSMELLTKCMRTKSTA-KFFRDHQAALKHNLPLGSFLLKPVQRILKYHLLLQEIEK--RLDKSTDGYEVVQD---ALSAMHGVAWHINEMKRKHEHAIRIQELRGLLINLKQ-DLSILGDLALEGSFRLHRTRKERALFLFDSSLLITKKRDDGMFLFKNEIKCRNLMILEQ-PRE-LEFCVWHYKNEKPRYTFQAKTQEEKSQWIHHIKRLILENHP-STVPDKAKNIILE 323
BLAST of DH domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008024.1 (pep scaffold:Pmarinus_7.0:GL476484:132482:154761:-1 gene:ENSPMAG00000007248.1 transcript:ENSPMAT00000008024.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 129.798 bits (325), Expect = 6.691e-33 Identity = 110/335 (32.84%), Postives = 186/335 (55.52%), Query Frame = 2
Query: 728 VMQELVETEHIYV---KSLME-----VEEGYMKMSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+ E+++TE +YV KS++E +E+ Y++ ND +V +F N + + F+S LE+L+ ++ + ++ECF+E+ G FE +Y++YCTN+ S++ L + T S A + Q L H LPL +FLLKPVQRILKYHL+L+E+ + +L VV+ AL M VA INE + + E +R +LR L + + LG L+G ++ R R + L +++L++ K+ +G + + IKC +M+ E P++ LEF V + K + T Q +EK W IK+LI+ ++ ++ ++AK I+L+
Sbjct: 7 VVLEILDTERMYVRHLKSIVESYVNLIEQDYLRAISQRLPND-DVNTLFGNIKEIYKFNSELLEELEDCSNDPVA----IAECFVEKSGGFE-IYTQYCTNFPSSMELLTKCMRTKSTA-KFFRDHQAALKHNLPLGSFLLKPVQRILKYHLLLQEIEK--RLDKSTDGYEVVQD---ALSAMHGVAWHINEMKRKHEHAIRIQELRGLLINLKQ-DLSILGDLALEGSFRLHRTRKERALFLFDSSLLITKKRDDGMFLFKNEIKCRNLMILEQ-PRE-LEFCVWHYKNEKPRYTFQAKTQEEKSQWIHHIKRLILENHP-STVPDKAKNIILE 325
BLAST of DH domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003234.1 (pep scaffold:Pmarinus_7.0:GL476714:93500:128189:1 gene:ENSPMAG00000002944.1 transcript:ENSPMAT00000003234.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 116.701 bits (291), Expect = 1.147e-27 Identity = 99/331 (29.91%), Postives = 172/331 (51.96%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKM---SDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLI-QCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+ E+++TE +YVK L + E Y+ + + + +EV +F N ++ + F E L + S F + +++CF+ + F +Y++YC NY ++ L+ E S A + Q L H LPL +LLKPVQRILKYHL+L+E+ + + A G +E + +A M VA IN+ + + E R +++ +L G L+G +V R+ R + L L+L KR + + + I C+ +ML E++PK+PL F V ++K + T+Q + EK +W +K+LI+ ++ I +AK+ +L+
Sbjct: 119 VVLEVLQTEQMYVKDLRSIVENYLGCIIDTPDLPLSPEEVCTLFGNIEDIYALN--FSELLHELESCAFDPVA-IADCFVAKNEAFH-IYTQYCMNYPNAIDVLN--ECARSVAMTRFFGEVQASLKHSLPLGCYLLKPVQRILKYHLLLREIANHYEGL----AEG-MEVIEEATATMTSVAWHINDIKRKHEHAARVQEIQAQLVQWQGPELCRYGELVLEGTFRVHRARHERSLFLFHCILLLTKRRDDA-YAYKAHILCSNLMLVEHVPKEPLSFSVRHFKNSKVQHTVQARSFDEKRLWIHELKRLILENHP-GKIPLKAKQAILE 436
BLAST of DH domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006386.1 (pep scaffold:Pmarinus_7.0:GL476470:857650:882189:-1 gene:ENSPMAG00000005742.1 transcript:ENSPMAT00000006386.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 81.2629 bits (199), Expect = 4.149e-16 Identity = 85/352 (24.15%), Postives = 161/352 (45.74%), Query Frame = 2
Query: 665 KFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGY---MKMSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQV-IKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
+ +L +G S +ER V+ E+++TE YV+ L + + Y M+ + + + +++ +F N R++ + L+ L++ ++ + CF+ + F+ +Y+EYC NY +V +H + + S +C + Q+ + + K V+ L L+ L + ++L+ALD M VA INE + E+ R ++ L G L+G +V RN R L N L+ A+R + + I+C + +L+ + ++FHV T + K Q + +EK +W +K+LI+ +Y D I +AK+ +LD
Sbjct: 100 RMTLAADGCSLSSLER-----VLLEMLQTERAYVRDLSSIVQDYLGCMEATPGLPLSSQDLGTLFGNVRSIYFLNRDLLQDLEVCGLDPVAA----ARCFISKSEAFQ-IYTEYCMNYPNTVGVVHAIPCNCVLSTSSEPRC-ARYKFQIVVISHKYKCVRWWLCRQLLGTGLKS-----QNAKRTATHRTVLEALDTMTGVAQHINEVKRRHEQASRVQEIERLLSSWHGPELGRYGELVLEGVFRVARARNQRTFFLFTNILLFARRRDHIYVCKGHILIECKQSVLYHPLVNSNMDFHVPHTRNRKLCHQYQAHSVEEKRLWVHELKRLILENYPSD-IPLKAKQAILD 434
BLAST of DH domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006962.1 (pep scaffold:Pmarinus_7.0:GL481838:263808:335470:1 gene:ENSPMAG00000006236.1 transcript:ENSPMAT00000006962.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 78.1814 bits (191), Expect = 1.235e-14 Identity = 66/206 (32.04%), Postives = 106/206 (51.46%), Query Frame = 2
Query: 707 EREKWHLVMQELVETEHIYVKSLMEVEEGYMK-MSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLK--LINSYEFSSLQR----------LSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQ 1285
E +K V+ ELVETE YVK L ++E Y++ + F + ++E +F R L IF FL+ L+ L + +F +L++ L FL HF+ LYS YC ++ ++ K L + + L + + H L ++L+KP+QR+LKY L+L+EL+ S + + L +AL M +VA+ INE Q
Sbjct: 559 EADKLRKVILELVETERSYVKDLCTLQEIYVEPLQKEAFLSPDQLEALFGTLRELVIFQKEFLQTLEQGLSLAPDFETLEQPAHFRRVLFSLGGSFLYYSDHFK-LYSAYCASHPKAQKLLETAKRDPAFG-AFLDERNPRRQHSSTLESYLIKPIQRVLKYPLLLRELVSLTDADSEENYH-----LTEALRAMNKVASHINEMQ 757
BLAST of DH domain-containing protein vs. Ensembl Yeast
Match: CDC24 (Guanine nucleotide exchange factor (GEF) for Cdc42p; required for polarity establishment and maintenance, and mutants have morphological defects in bud formation and shmooing; relocalizes from nucleus to cytoplasm upon DNA replication stress; thermosensitivity of the cdc24-4 mutant in the presence of sorbitol is functionally complemented by human CDC42 [Source:SGD;Acc:S000000039]) HSP 1 Score: 60.8474 bits (146), Expect = 1.239e-9 Identity = 56/190 (29.47%), Postives = 91/190 (47.89%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHL----HRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQ 1285
+++E V TE YV L +++ ++ DS +E+ ++F N + F FL L+ IN+ S QR+ F+ HF LY + +++ L H+M S Q I + ++L L +FL KPVQR+ +Y L++KE L++ S + + L ALD +A INE Q
Sbjct: 282 IIKEFVATERKYVHDLEILDKYRQQLLDSNLITSEELYMLFPNLGDAIDFQRRFLISLE-INALVEPSKQRIGALFMHS-KHFFKLYEPWSIGQNAAIEFLSSTLHKMRVDES---QRFI-----INNKLELQSFLYKPVQRLCRYPLLVKE------LLAESSDDNNTKELEAALDISKNIARSINENQ 455
BLAST of DH domain-containing protein vs. Ensembl Nematostella
Match: EDO32328 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVF8]) HSP 1 Score: 86.6557 bits (213), Expect = 4.692e-17 Identity = 92/332 (27.71%), Postives = 144/332 (43.37%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYM--------KMSDSIFSNDKEVELIFSNWRNLRIFHSL-FLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLI-------QCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNS-RLVLLCENALVLAKRLGNG------KWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLII 1654
+M ELV TE YV+ L + GY+ K+ +F + E IF N + FH FLE+L + + + + + F E G FE Y+ YC N AS A Q + +CQ LGH+LPL+ +LLKPVQRI KY L+L+E+++ K N L++A M V +N+ + L+ + PFL Y K+P + S R V L E ++ +KR + + + IK +++ + E I PL+F + LQ N++ KE W I+ +++
Sbjct: 488 IMAELVTTEKDYVRDLDHIVRGYLHEFERAAGKIPIELFD---QRETIFGNIEEILEFHRCDFLEELNKCSE----TPKSVGKVFTERRGEFEK-YALYCKN------------KPASEALQQQLINVPYIRECQANLGHKLPLTAYLLKPVQRITKYQLLLREMMKNTKNDRIAYMN-----LMEAFHAMQNVLRHLND--VMHSSGLKGYHGNLGDLGKLLLQDPFL-VWYTGARRKLPPLKGSQRQVFLYEKMVIFSKREEDSTTKDAVTYHFKNSIKTSDVGITETINGAPLKFELW-LPGRTEVFLLQANNSEIKERWISEIRSVLL 790
BLAST of DH domain-containing protein vs. Ensembl Nematostella
Match: EDO43752 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXC9]) HSP 1 Score: 85.1149 bits (209), Expect = 1.705e-16 Identity = 92/349 (26.36%), Postives = 145/349 (41.55%), Query Frame = 2
Query: 725 LVMQELVETEHIYV---KSLMEVEE----------------GYMKMSDSIFSNDKEV--------ELIFSNWRNLRIFHS-LFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCR------NSRLVLLCENALVLAKRL----GNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTT--DNKNKATLQVMNAQEKEMWCKMIKQLI 1651
++ EL++TE YV K ++EV GY + ++ S+ +V +IF N +++ FHS FL++++ YE + + + E F+E F Y YC N S L H Q GH L +S +L+KPVQRI KY L+LK+L+ CC+ G SL LD ML V R N+ N LG L V + R V L E ALV +K G + + +K +E+ + E+I + P +F V +++K ++ N + K++W K +++LI
Sbjct: 1209 FIVNELLQTERAYVGDLKCVIEVSSVRISSKRRMPLRISLSGYCAVFPALRSSAYDVPAGLVGKESIIFGNIQDIYKFHSNTFLQEME---KYE-THPEDVGEAFIEWGETFVRFYVSYCKNKPFSNSLL------IEHGGNFFSDLQASYGHGLSISAYLIKPVQRITKYQLLLKDLLTCCE--------GSENSLQAGLDVMLSVPRRANDAMYVNMLHGLEE------------NLDHLGRIILQDAFTVFDPKLLRRKGKDRHVFLFEQALVFSKETKDNDGKVSYLYKYKLKTSELGVTEHIAEDPCKFAVWTGKPPQSEDKRVIKAANIEVKQLWVKELRELI 1527
BLAST of DH domain-containing protein vs. Ensembl Nematostella
Match: EDO44980 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUA3]) HSP 1 Score: 68.1662 bits (165), Expect = 2.902e-11 Identity = 59/218 (27.06%), Postives = 96/218 (44.04%), Query Frame = 2
Query: 713 EKWHLVMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDK--EVELIFSNWRNLRIFHSLFLEKLKLINSYEFS----SLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMET--TASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGV---------------------VESLLKALDNMLQVANRINE 1279
E+ V+ EL+ TE Y++ L +K N K + E++F N HS+ +L+ S+E + Q L +CF E +++YS YC N+ ++ L + E A A++ + LS+FL+KPVQR+LKY L+L EL++ + S ++L++AL M +VA INE
Sbjct: 976 EQRQKVLTELLNTERDYIRDLQTC----LKYFYEELKNTKVVDAEVLFGN------MHSVVETSTRLLGSFEAALQDDKQQELGKCFAEHAEEIKSVYSTYCKNHDDAIGLLEKYEDCLEAQEAFRKCLDAVRDTTKCWDLSSFLIKPVQRVLKYPLLLSELLKVIPYKVYGSTAKCKTIRIKYMARLLKCTPQIHKDKDNLVRALSAMTEVAATINE 1183
BLAST of DH domain-containing protein vs. Ensembl Nematostella
Match: EDO45201 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTF1]) HSP 1 Score: 66.6254 bits (161), Expect = 3.255e-11 Identity = 60/191 (31.41%), Postives = 97/191 (50.79%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYMKMSD---SIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRM--ETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQ 1285
V+ E++ TE YVK+L +V EGY+ + +FS D ++ L+FSN + FH L +L+ + + FLE F+ +YSEYC N+ ++ L + H +++ Q + + L FLL PVQ+I KY L L EL++ +H + V + AL M +VA+ INE++
Sbjct: 96 VVNEILNTEKDYVKNLSDVVEGYLCQAQKRVDMFSED-QIYLLFSNIEQIYEFHQKLLLQLEDCYLKDNPCDSMIGRVFLENKEGFQ-IYSEYCNNHPHAIAELKTLCESNNYKHFFEACRLLQDMIN--ISLDGFLLTPVQKICKYPLQLAELLKHT-YPTHKDYDAVHD----ALRTMKEVASLINERK 277
BLAST of DH domain-containing protein vs. Ensembl Nematostella
Match: EDO43753 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXD0]) HSP 1 Score: 63.929 bits (154), Expect = 4.803e-11 Identity = 43/158 (27.22%), Postives = 83/158 (52.53%), Query Frame = 2
Query: 725 LVMQELVETEHIYVKSLMEVEEGYMK------MSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQ 1180
V++EL++TE YV SL EV +GY+ + + + ++ ++F N + + +H LEK + + ++L+ FL+ + +Y YC N +S +H + T + +LG++L + +L+KPVQR++KY L+LK+ ++
Sbjct: 1 FVLRELIQTEQDYVTSLGEVVDGYIAEFSKPDLPEELKGKER---MVFGNIKQIYEWHKTELEKCE-------DAPEKLASVFLKAERRLQ-MYVIYCQNKPKSTALVHEFKET------YFTDMKDRLGYRLSIEDYLIKPVQRVMKYQLLLKDFVK 141
BLAST of DH domain-containing protein vs. Ensembl Medaka
Match: PLEKHG1 (pleckstrin homology and RhoGEF domain containing G1 [Source:NCBI gene;Acc:101161938]) HSP 1 Score: 125.946 bits (315), Expect = 1.863e-28 Identity = 105/334 (31.44%), Postives = 177/334 (52.99%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYM----KMSD-SIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLI-QCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVV-ESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+QE+++TE YV+ L + E Y+ K S ++ S DK +F N R++ F+ L L+ NS + ++ECF+ + F +Y++YCTNY +SV L E + A + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ + E + +A+D M +VA IN+ + + E +R +++ L + + G L+G ++ +N R + L + L++ K+ + + I C +ML E IPK+PL F V + K + T+Q + Q+K MW +K+LI+ ++ I +AK+ +L+
Sbjct: 164 VVQEILDTERTYVQDLRSIVEDYLECISKQSRLALSSQDKSS--LFGNIRDIYHFNRDLLHHLEKCNSDPVA----IAECFVCKSEEFH-IYTQYCTNYPRSVAVL--TECMRNKALAKFFRERQESLRHALPLGSYLLKPVQRILKYHLLLHE------IANHMEKDTETHEVVQEAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLIGYGELVLEGTFRLQRAKNERTLFLFDKLLLITKKR-EETYTYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRMWILHLKRLILENHPA-KIPAKAKQAILE 480
BLAST of DH domain-containing protein vs. Ensembl Medaka
Match: PLEKHG1 (pleckstrin homology and RhoGEF domain containing G1 [Source:NCBI gene;Acc:101161938]) HSP 1 Score: 125.946 bits (315), Expect = 1.955e-28 Identity = 105/334 (31.44%), Postives = 177/334 (52.99%), Query Frame = 2
Query: 728 VMQELVETEHIYVKSLMEVEEGYM----KMSD-SIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLI-QCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVV-ESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
V+QE+++TE YV+ L + E Y+ K S ++ S DK +F N R++ F+ L L+ NS + ++ECF+ + F +Y++YCTNY +SV L E + A + Q L H LPL ++LLKPVQRILKYHL+L E + +H+ + E + +A+D M +VA IN+ + + E +R +++ L + + G L+G ++ +N R + L + L++ K+ + + I C +ML E IPK+PL F V + K + T+Q + Q+K MW +K+LI+ ++ I +AK+ +L+
Sbjct: 111 VVQEILDTERTYVQDLRSIVEDYLECISKQSRLALSSQDKSS--LFGNIRDIYHFNRDLLHHLEKCNSDPVA----IAECFVCKSEEFH-IYTQYCTNYPRSVAVL--TECMRNKALAKFFRERQESLRHALPLGSYLLKPVQRILKYHLLLHE------IANHMEKDTETHEVVQEAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGPDLIGYGELVLEGTFRLQRAKNERTLFLFDKLLLITKKR-EETYTYKAHILCCNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRMWILHLKRLILENHPA-KIPAKAKQAILE 427
BLAST of DH domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000046986.1 (pleckstrin homology domain-containing family G member 3 [Source:NCBI gene;Acc:101157827]) HSP 1 Score: 123.25 bits (308), Expect = 1.201e-27 Identity = 106/358 (29.61%), Postives = 182/358 (50.84%), Query Frame = 2
Query: 665 KFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKE------VELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLH---RMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSA-NGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
+ ++ PN NL ++R V+ E++ETE +YV+ L+ + E Y+ I + K+ V +F N ++ F++ L+ L + + + ++ CF+E+ +F+ +Y++YCTNY SV L R ++TA Q Q L LPL ++LLKPVQRILKYHL+L+E+ + H E + +A++ M VA IN+ + + E +R +++ L + + G L+G KV +N R + L + L+ KR G + + I C +ML E K L F V + K T+Q +EK++W IK++I+ ++ H I ++AK +L+
Sbjct: 152 RATMAPNPNLTY-LDR-----VIMEIIETERMYVRDLLIIVEDYLAC---IIDHPKQLIHPDQVCALFGNITDIYAFNNELLQDLDMCENDPVA----IARCFVEKREYFD-IYTQYCTNYPNSVAALTECLRDKSTA----QFFRDRQASLKRTLPLGSYLLKPVQRILKYHLLLQEIAK------HFDPEEEGYEDVEEAINTMTGVAWYINDMKRKHEHAVRLQEVQSLLLNWKGPDLASYGELVLEGTFKVHRAKNERTLFLFDRMLLFTKRRGE-HYVYKTDIPCTTLMLIESA-KDSLSFSVTKYKNPKQPYTVQAKTVEEKKLWAHHIKRIIVENH-HAVIPQKAKEAILE 482
BLAST of DH domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000019753.2 (pleckstrin homology domain-containing family G member 3 [Source:NCBI gene;Acc:101157827]) HSP 1 Score: 123.25 bits (308), Expect = 1.203e-27 Identity = 106/358 (29.61%), Postives = 182/358 (50.84%), Query Frame = 2
Query: 665 KFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKE------VELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLH---RMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSA-NGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
+ ++ PN NL ++R V+ E++ETE +YV+ L+ + E Y+ I + K+ V +F N ++ F++ L+ L + + + ++ CF+E+ +F+ +Y++YCTNY SV L R ++TA Q Q L LPL ++LLKPVQRILKYHL+L+E+ + H E + +A++ M VA IN+ + + E +R +++ L + + G L+G KV +N R + L + L+ KR G + + I C +ML E K L F V + K T+Q +EK++W IK++I+ ++ H I ++AK +L+
Sbjct: 171 RATMAPNPNLTY-LDR-----VIMEIIETERMYVRDLLIIVEDYLAC---IIDHPKQLIHPDQVCALFGNITDIYAFNNELLQDLDMCENDPVA----IARCFVEKREYFD-IYTQYCTNYPNSVAALTECLRDKSTA----QFFRDRQASLKRTLPLGSYLLKPVQRILKYHLLLQEIAK------HFDPEEEGYEDVEEAINTMTGVAWYINDMKRKHEHAVRLQEVQSLLLNWKGPDLASYGELVLEGTFKVHRAKNERTLFLFDRMLLFTKRRGE-HYVYKTDIPCTTLMLIESA-KDSLSFSVTKYKNPKQPYTVQAKTVEEKKLWAHHIKRIIVENH-HAVIPQKAKEAILE 501
BLAST of DH domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000035892.1 (pleckstrin homology domain-containing family G member 3 [Source:NCBI gene;Acc:101157827]) HSP 1 Score: 123.25 bits (308), Expect = 1.247e-27 Identity = 106/358 (29.61%), Postives = 182/358 (50.84%), Query Frame = 2
Query: 665 KFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKE------VELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLH---RMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSA-NGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLD 1708
+ ++ PN NL ++R V+ E++ETE +YV+ L+ + E Y+ I + K+ V +F N ++ F++ L+ L + + + ++ CF+E+ +F+ +Y++YCTNY SV L R ++TA Q Q L LPL ++LLKPVQRILKYHL+L+E+ + H E + +A++ M VA IN+ + + E +R +++ L + + G L+G KV +N R + L + L+ KR G + + I C +ML E K L F V + K T+Q +EK++W IK++I+ ++ H I ++AK +L+
Sbjct: 190 RATMAPNPNLTY-LDR-----VIMEIIETERMYVRDLLIIVEDYLAC---IIDHPKQLIHPDQVCALFGNITDIYAFNNELLQDLDMCENDPVA----IARCFVEKREYFD-IYTQYCTNYPNSVAALTECLRDKSTA----QFFRDRQASLKRTLPLGSYLLKPVQRILKYHLLLQEIAK------HFDPEEEGYEDVEEAINTMTGVAWYINDMKRKHEHAVRLQEVQSLLLNWKGPDLASYGELVLEGTFKVHRAKNERTLFLFDRMLLFTKRRGE-HYVYKTDIPCTTLMLIESA-KDSLSFSVTKYKNPKQPYTVQAKTVEEKKLWAHHIKRIIVENH-HAVIPQKAKEAILE 520
BLAST of DH domain-containing protein vs. Planmine SMEST
Match: SMESG000017234.1 (SMESG000017234.1) HSP 1 Score: 1515.75 bits (3923), Expect = 0.000e+0 Identity = 745/748 (99.60%), Postives = 746/748 (99.73%), Query Frame = 2
Query: 347 MQQRYTTEENGKPDRCKSRSTLSLLWDEICGPNELQKFMETCFNDHKIIDIEIGETVDPPLHSAVVKSHLKDSGTSSLNDEDQCFVFEKDKLLQSRPQATVKHIVNKFSLCPNGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMXXXXXXXXXXXXXXXYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLDNKHNVLSQCQPISNDVLEKFQVTLNRENDVLDLESSLRKMFDPVSTQSSQSKHKSIKRRNSVGAIKSESKINYRDPSIYQWSGRRHYANEDDVDCRSIMVDVNEENYYSRSGQQLSPYEKSYEQYTSKSRNKIRLTSDDIKEIFQPLKQMQENSDNSSVLLGEMELASLCSDADLDSVASDNATNNQHKRKSTSMDRTFGISLYAKANSFTSSMDTNSSTSREFNNNNIIGSSRAKKFLFSSVRETKTTRSNSDWGALFDGEPKPSLVKRFFKASAKLAKRDKNKSVNCAVEIE 2590
MQQRYTTEENGKPDRCKSRSTLSLLWDEICGPNELQKFMETCFNDHKIIDIEIGETVDPPLHSAVVKSHLKDSGTSSLNDEDQCFVFEKDKLLQSRPQATVKHIVNKFSLCPN NLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGY+KMSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMEREEQLRRLKLRDELYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLDNKHNVLSQCQPISNDVLEKFQVTLNRENDVLDLESSLRKMFDPVSTQSSQSKHKSIKRRNSVGAIKSESKINYRDPSIYQWSGRRHYANEDDVDCRSIMVDVNEENYYSRSGQQLSPYEKSYEQYTSKSRNKIRLTSDDIKEIFQPLKQMQENSDNSSVLLGEMELASLCSDADLDSVASDNATNNQHKRKSTSMDRTFGISLYAKANSFTSSMDTNSSTSREFNNNNIIGS RAKKFLFSSVRETKTTRSNSDWGALFDGEPKPSLVKRFFKASAKLAKRDKNKSVNCAVEIE
Sbjct: 1 MQQRYTTEENGKPDRCKSRSTLSLLWDEICGPNELQKFMETCFNDHKIIDIEIGETVDPPLHSAVVKSHLKDSGTSSLNDEDQCFVFEKDKLLQSRPQATVKHIVNKFSLCPNANLNSDIEREKWHLVMQELVETEHIYVKSLMEVEEGYLKMSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGHQLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQMEREEQLRRLKLRDELYDSDIFNCPFLGTPYLDGELKVPGCRNSRLVLLCENALVLAKRLGNGKWGVRQVIKCNEMMLFEYIPKQPLEFHVIDTTDNKNKATLQVMNAQEKEMWCKMIKQLIISSYEHDSISERAKRILLDNKHNVLSQCQPISNDVLEKFQVTLNRENDVLDLESSLRKMFDPVSTQSSQSKHKSIKRRNSVGAIKSESKINYRDPSIYQWSGRRHYANEDDVDCRSIMVDVNEENYYSRSGQQLSPYEKSYEQYTSKSRNKIRLTSDDIKEIFQPLKQMQENSDNSSVLLGEMELASLCSDADLDSVASDNATNNQHKRKSTSMDRTFGISLYAKANSFTSSMDTNSSTSREFNNNNIIGSLRAKKFLFSSVRETKTTRSNSDWGALFDGEPKPSLVKRFFKASAKLAKRDKNKSVNCAVEIE 748
BLAST of DH domain-containing protein vs. Planmine SMEST
Match: SMESG000013025.1 (SMESG000013025.1) HSP 1 Score: 260.766 bits (665), Expect = 1.271e-72 Identity = 133/134 (99.25%), Postives = 134/134 (100.00%), Query Frame = 2
Query: 2621 VLSNTFHPQMSTSHIIPNYAAFNRQQAPLHFIPHQTNNHSFFPPSGQIPLYNRMQNTSGHIAGPNQRFSTESIHHQQDQMPIAYNFSKNLTNLQQQAFGGNMITNNNNALKXXXXXXXXXXXXDSGYFGNKTPR 3022
V+SNTFHPQMSTSHIIPNYAAFNRQQAPLHFIPHQTNNHSFFPPSGQIPLYNRMQNTSGHIAGPNQRFSTESIHHQQDQMPIAYNFSKNLTNLQQQAFGGNMITNNNNALKINEIINNNSNSSDSGYFGNKTPR
Sbjct: 662 VISNTFHPQMSTSHIIPNYAAFNRQQAPLHFIPHQTNNHSFFPPSGQIPLYNRMQNTSGHIAGPNQRFSTESIHHQQDQMPIAYNFSKNLTNLQQQAFGGNMITNNNNALKINEIINNNSNSSDSGYFGNKTPR 795
BLAST of DH domain-containing protein vs. Planmine SMEST
Match: SMESG000070268.1 (SMESG000070268.1) HSP 1 Score: 63.1586 bits (152), Expect = 1.691e-9 Identity = 47/170 (27.65%), Postives = 91/170 (53.53%), Query Frame = 2
Query: 683 NGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEE-GYMKMSDSIFSNDKEVELIFSNWRNL--RIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLG-HQLPLSTFLLKPVQRILKYHLILKELIQ 1180
N L D +R ++++ +EL+ETE Y + L EV Y + S +E++ IF NW +L + ++ K++ NS +Q + + L +F +Y +C+ Q++ L + + T++ + QC+ L ++P+S++ LKP+QRI KY LI++ +++
Sbjct: 1121 NAILTEDEKRRQFYI--RELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNF-IVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILK 1287
BLAST of DH domain-containing protein vs. Planmine SMEST
Match: SMESG000070268.1 (SMESG000070268.1) HSP 1 Score: 63.1586 bits (152), Expect = 1.744e-9 Identity = 47/170 (27.65%), Postives = 91/170 (53.53%), Query Frame = 2
Query: 683 NGNLNSDIEREKWHLVMQELVETEHIYVKSLMEVEE-GYMKMSDSIFSNDKEVELIFSNWRNL--RIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLG-HQLPLSTFLLKPVQRILKYHLILKELIQ 1180
N L D +R ++++ +EL+ETE Y + L EV Y + S +E++ IF NW +L + ++ K++ NS +Q + + L +F +Y +C+ Q++ L + + T++ + QC+ L ++P+S++ LKP+QRI KY LI++ +++
Sbjct: 454 NAILTEDEKRRQFYI--RELIETEKAYYEDLQEVHRVFYEPIKKSNLLTLEELKHIFINWTDLIPKSYNFYMALKIRKDNSGNKQPIQCVGDILLSNFPNF-IVYVRFCSLQNQAIALLEKKKQTSAKFKEFCQQCEENLRCKKMPMSSYFLKPMQRITKYKLIVENILK 620
BLAST of DH domain-containing protein vs. Planmine SMEST
Match: SMESG000056121.1 (SMESG000056121.1) HSP 1 Score: 59.6918 bits (143), Expect = 1.920e-8 Identity = 52/195 (26.67%), Postives = 92/195 (47.18%), Query Frame = 2
Query: 713 EKWHLVMQELVETEHIYVKSLMEVEEGYMKMSDSIFSNDKEVELIFSNWRNLRIFHSLFLEKLKLINSYEFSSLQRLSECFLEEIGHFEALYSEYCTNYTQSVKHLHRMETTASHAWQSLIQCQTQLGH----QLPLSTFLLKPVQRILKYHLILKELIQCCKLMSHVSANGVVESLLKALDNMLQVANRINEKQ 1285
+K +++E++ETE +++ L E + K D++ L+F + +++ FL KL N + + FL+ + FE +Y EYC NY + + +++ ++ AS+ + +L L L+KP+QR LKY L LK +I+ L H N L+ A +A +INEK+
Sbjct: 458 QKRSKIIEEILETEKKFIQDLKITLEAFDKNLIPAKIPDQDFHLLFGDLKSVIAVAEEFLSKLSA-NMEDGLDKIAVGSVFLQSVSSFEEVYKEYCVNYDRKLDLINK-KSKASNVTDFVSDGLNRLNDLGVFASTLDMMLVKPLQRFLKYPLFLKTIIENT-LPDHPDIN----DLIAASSEFDVLAQKINEKK 645 The following BLAST results are available for this feature:
BLAST of DH domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of DH domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of DH domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of DH domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of DH domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of DH domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of DH domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of DH domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of DH domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of DH domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of DH domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of DH domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of DH domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of DH domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30023509 ID=SMED30023509|Name=DH domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=4461bpback to top protein sequence of SMED30023509-orf-1 >SMED30023509-orf-1 ID=SMED30023509-orf-1|Name=SMED30023509-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=893bp MQQRYTTEENGKPDRCKSRSTLSLLWDEICGPNELQKFMETCFNDHKIIDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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