Carboxylic ester hydrolase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30023427 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Carboxylic ester hydrolase vs. Ensembl Human
Match: BCHE (butyrylcholinesterase [Source:HGNC Symbol;Acc:HGNC:983]) HSP 1 Score: 260.766 bits (665), Expect = 1.476e-78 Identity = 188/557 (33.75%), Postives = 284/557 (50.99%), Query Frame = 3
Query: 153 LICLDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGI---LQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNLSEVFRN------YDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
L+C+ I K H T+ + + NG V+G V + FL IPY +PP+G LRF+KPQ + +S I N K+ Q + F G + E W P E+ LY+NVW P + +N VL+WIYGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++L + GN+G++DQ ALQW+ +NI+ F GNPK+VT+ G SAG SVSLHLL S F AI+ SG + W + E R+R+ L K +REN+ IIK L+N + +E LL+ V L + P VDG+ + D P L +FK + +EGT F++ P DN+ +I K F + + + FP + S+ ++ I Y P + L ++ D FI ++E S+ + ++ +FE + WP W GVMH EI ++FG L ++ ++ S I+K + NF K+GN +E N + + Y+ +N + ++ I +K + + RFW
Sbjct: 18 LLCMLIG-KSH-TEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWS-DIWNATKYANSCCQNIDQSFPGFH-GSEMWNPNTDLSEDCLYLNVWIPA---PKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLN-----LAKLT-------GCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF--FPGV-SEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTE--STRIMTKLRAQQCRFW 550
BLAST of Carboxylic ester hydrolase vs. Ensembl Human
Match: BCHE (butyrylcholinesterase [Source:HGNC Symbol;Acc:HGNC:983]) HSP 1 Score: 259.61 bits (662), Expect = 9.714e-78 Identity = 188/557 (33.75%), Postives = 284/557 (50.99%), Query Frame = 3
Query: 153 LICLDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGI---LQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNLSEVFRN------YDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
L+C+ I K H T+ + + NG V+G V + FL IPY +PP+G LRF+KPQ + +S I N K+ Q + F G + E W P E+ LY+NVW P + +N VL+WIYGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++L + GN+G++DQ ALQW+ +NI+ F GNPK+VT+ G SAG SVSLHLL S F AI+ SG + W + E R+R+ L K +REN+ IIK L+N + +E LL+ V L + P VDG+ + D P L +FK + +EGT F++ P DN+ +I K F + + + FP + S+ ++ I Y P + L ++ D FI ++E S+ + ++ +FE + WP W GVMH EI ++FG L ++ ++ S I+K + NF K+GN +E N + + Y+ +N + ++ I +K + + RFW
Sbjct: 18 LLCMLIG-KSH-TEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWS-DIWNATKYANSCCQNIDQSFPGFH-GSEMWNPNTDLSEDCLYLNVWIPA---PKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLN-----LAKLT-------GCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF--FPGV-SEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTE--STRIMTKLRAQQCRFW 550
BLAST of Carboxylic ester hydrolase vs. Ensembl Human
Match: BCHE (butyrylcholinesterase [Source:HGNC Symbol;Acc:HGNC:983]) HSP 1 Score: 252.677 bits (644), Expect = 8.166e-76 Identity = 181/520 (34.81%), Postives = 266/520 (51.15%), Query Frame = 3
Query: 153 LICLDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGI---LQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNLSEVFRNY 1682
L+C+ I K H T+ + + NG V+G V + FL IPY +PP+G LRF+KPQ + +S I N K+ Q + F G + E W P E+ LY+NVW P + +N VL+WIYGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++L + GN+G++DQ ALQW+ +NI+ F GNPK+VT+ G SAG SVSLHLL S F AI+ SG + W + E R+R+ L K +REN+ IIK L+N + +E LL+ V L + P VDG+ + D P L +FK + +EGT F++ P DN+ +I K F + + + FP + S+ ++ I Y P + L ++ D FI ++E S+ + ++ +FE + WP W GVMH EI ++FG L ++ ++ S I+K + NF K+G S NY
Sbjct: 18 LLCMLIG-KSH-TEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWS-DIWNATKYANSCCQNIDQSFPGFH-GSEMWNPNTDLSEDCLYLNVWIPA---PKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLN-----LAKL-------TGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF--FPGV-SEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGCSSSTILNY 515
BLAST of Carboxylic ester hydrolase vs. Ensembl Human
Match: ACHE (acetylcholinesterase (Cartwright blood group) [Source:HGNC Symbol;Acc:HGNC:108]) HSP 1 Score: 216.853 bits (551), Expect = 1.289e-61 Identity = 151/549 (27.50%), Postives = 250/549 (45.54%), Query Frame = 3
Query: 201 LNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQN------INFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQY-YPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYL--TQQSETRQSATSIKIMKEFGNFVKHGNLSEV-------FRNYDESSNAYIKINEDLWTSAIFSKDQINKVRFWEKLRRKF 1796
L +V G ++G K ++ FL IP+ +PP+G RF P+P +S +++ F + Q ++ G E W P E+ LY+NVW P + PVLVWIYGGG+ SG+SSL++YDG L E ++VS NYR+ GF++L GN+G+ DQ ALQW+ EN++ F G+P +VT+ G SAG SV +HLL S F A++ SG W + E R R+ + + + T N ++ L+ +N + +L E + +F++ P VDG+ + D P L N F + V +EG+YF++ P DN +I F + P + +++ + +P+ + L ++ D + +LA ++ ++VY FE WP W GV H EI ++FG L ++ + + ++M+ + NF + G+ +E + Y + Y+ + DL + + FW + K
Sbjct: 39 LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWS-GVVDATTFQSVCYQYVDTLYPGFE-GTEMWNPNRELSEDCLYLNVWTPYP--RPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLV--------GCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQE---SVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSL--DLRPLEVRRGLRAQACAFWNRFLPKL 570
BLAST of Carboxylic ester hydrolase vs. Ensembl Human
Match: ACHE (acetylcholinesterase (Cartwright blood group) [Source:HGNC Symbol;Acc:HGNC:108]) HSP 1 Score: 216.853 bits (551), Expect = 1.289e-61 Identity = 151/549 (27.50%), Postives = 250/549 (45.54%), Query Frame = 3
Query: 201 LNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQN------INFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQY-YPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYL--TQQSETRQSATSIKIMKEFGNFVKHGNLSEV-------FRNYDESSNAYIKINEDLWTSAIFSKDQINKVRFWEKLRRKF 1796
L +V G ++G K ++ FL IP+ +PP+G RF P+P +S +++ F + Q ++ G E W P E+ LY+NVW P + PVLVWIYGGG+ SG+SSL++YDG L E ++VS NYR+ GF++L GN+G+ DQ ALQW+ EN++ F G+P +VT+ G SAG SV +HLL S F A++ SG W + E R R+ + + + T N ++ L+ +N + +L E + +F++ P VDG+ + D P L N F + V +EG+YF++ P DN +I F + P + +++ + +P+ + L ++ D + +LA ++ ++VY FE WP W GV H EI ++FG L ++ + + ++M+ + NF + G+ +E + Y + Y+ + DL + + FW + K
Sbjct: 39 LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWS-GVVDATTFQSVCYQYVDTLYPGFE-GTEMWNPNRELSEDCLYLNVWTPYP--RPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLV--------GCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQE---SVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSL--DLRPLEVRRGLRAQACAFWNRFLPKL 570
BLAST of Carboxylic ester hydrolase vs. Ensembl Celegans
Match: ace-1 (Acetylcholinesterase 1 [Source:UniProtKB/Swiss-Prot;Acc:P38433]) HSP 1 Score: 202.216 bits (513), Expect = 1.190e-56 Identity = 146/531 (27.50%), Postives = 250/531 (47.08%), Query Frame = 3
Query: 228 VQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMR---IFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRS---------------KKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNI------DVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVLNE----PSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQS---ETRQSATSIKIMKEFGNFVKHGNLSEVFRNYDESSNAYIKINEDLW 1727
V QT K L R F IP+ +PP+G LRF+KP+P + + T PP ++ + G+ W + E+ LY+NV+ P ++ K+ V+VW+YGGG+ SG+++L++YDG +L +EN+I+V+ NYR+++ GF+ ++ GN+G+WDQ+ A++W+H+NI F G+ +T+ G SAG SVS+H+L KS YF AI+ SG S W ++ R+ ++IL+ F + + + REN+ A ++ + F W P VDG+ + ++ + + FK + + +E YF+ + P+I + D + + + + I+ Q T + EY + P I+ +D+++ D +F E+A +K YY +F + WP W GV+H EI ++FG L Q+ + S + M+ + NF K G D + N +D+W
Sbjct: 34 VLSQTGKPLTR----FQGIPFAEPPVGNLRFKKPKPKQPWRIPLNA-----TTPPNSCIQSEDTYFGDFYGSTMWNANTKLSEDCLYLNVYVPGKVDPNKK-LAVMVWVYGGGFWSGTATLDVYDGRILTVEENVILVAMNYRVSIFGFLYMNRPEAPGNMGMWDQLLAMKWVHKNIDLFGGDLSRITLFGESAGAASVSIHMLSPKSAPYFHRAIIQSGSATSPWAIEPRDVALARAVILYNAMKCGNMSLINPDYDRILDCF---QRADADALRENEWAPVREFGD------------------FPWVPVVDGDFLLENAQTSLKQGNFKKTQLLAGSNRDESIYFLTYQLPDIFPVADFFTKTDFIKDRQLWIKGVKDLLPRQILKCQLTLAAVLHEYEPQDLPVTPRDWINAMDKMLGDYHFTCSVNEMALAHTKHGGDTYYYYFTHRASQQTWPEWMGVLHGYEINFIFGEPLNQKRFNYTDEERELSNRFMRYWANFAKTG---------DPNKNEDGSFTQDVW 524
BLAST of Carboxylic ester hydrolase vs. Ensembl Celegans
Match: ace-1 (Acetylcholinesterase 1 [Source:UniProtKB/Swiss-Prot;Acc:P38433]) HSP 1 Score: 202.216 bits (513), Expect = 1.190e-56 Identity = 146/531 (27.50%), Postives = 250/531 (47.08%), Query Frame = 3
Query: 228 VQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMR---IFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRS---------------KKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNI------DVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVLNE----PSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQS---ETRQSATSIKIMKEFGNFVKHGNLSEVFRNYDESSNAYIKINEDLW 1727
V QT K L R F IP+ +PP+G LRF+KP+P + + T PP ++ + G+ W + E+ LY+NV+ P ++ K+ V+VW+YGGG+ SG+++L++YDG +L +EN+I+V+ NYR+++ GF+ ++ GN+G+WDQ+ A++W+H+NI F G+ +T+ G SAG SVS+H+L KS YF AI+ SG S W ++ R+ ++IL+ F + + + REN+ A ++ + F W P VDG+ + ++ + + FK + + +E YF+ + P+I + D + + + + I+ Q T + EY + P I+ +D+++ D +F E+A +K YY +F + WP W GV+H EI ++FG L Q+ + S + M+ + NF K G D + N +D+W
Sbjct: 34 VLSQTGKPLTR----FQGIPFAEPPVGNLRFKKPKPKQPWRIPLNA-----TTPPNSCIQSEDTYFGDFYGSTMWNANTKLSEDCLYLNVYVPGKVDPNKK-LAVMVWVYGGGFWSGTATLDVYDGRILTVEENVILVAMNYRVSIFGFLYMNRPEAPGNMGMWDQLLAMKWVHKNIDLFGGDLSRITLFGESAGAASVSIHMLSPKSAPYFHRAIIQSGSATSPWAIEPRDVALARAVILYNAMKCGNMSLINPDYDRILDCF---QRADADALRENEWAPVREFGD------------------FPWVPVVDGDFLLENAQTSLKQGNFKKTQLLAGSNRDESIYFLTYQLPDIFPVADFFTKTDFIKDRQLWIKGVKDLLPRQILKCQLTLAAVLHEYEPQDLPVTPRDWINAMDKMLGDYHFTCSVNEMALAHTKHGGDTYYYYFTHRASQQTWPEWMGVLHGYEINFIFGEPLNQKRFNYTDEERELSNRFMRYWANFAKTG---------DPNKNEDGSFTQDVW 524
BLAST of Carboxylic ester hydrolase vs. Ensembl Celegans
Match: ace-2 (Carboxylic ester hydrolase [Source:UniProtKB/TrEMBL;Acc:G5EDV9]) HSP 1 Score: 196.438 bits (498), Expect = 1.622e-54 Identity = 158/541 (29.21%), Postives = 245/541 (45.29%), Query Frame = 3
Query: 222 GLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCP-------PQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTG----ILQFAWAPC-VDGELIKDDPRRLFNEKKFKI-CPTIFLNVANEGTYFI--ISRFPNI-----------DVDNHKMIDNKYFTQTFQ-YYPHFP-----IICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISK---SNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG------HYLTQQSETRQSATSIKIMKEFGNFVKHGNLSEVFRNYDESSNAYIKINE 1718
G ++G + ++ FL +PY KPPIG RF+ + +S + R TC PQ P E W P E+ L +N+W P E + V+VWIYGGG+ SG+ SL++Y GSV A+KE+ IVV+ NYR+ GF+ DD + GN+G+ DQ AL+W+HENI F G+ VT+ G SAG S + HL S +YF+N I SG ++ W T + D S + K+ + + AI+K L+++ + + ++G + FA+ P D + D + K+FK IF +V +EGTY++ P D N +I ++ ++ + + P+F + ++ + +S V E D + R + D +F I+ A+LIS N +YY + + P WP W GVMH EI Y FG H Q + S IM+ + NF G + Y++ I++ E
Sbjct: 46 GTIRGVGQTFDGAKVSAFLGVPYAKPPIGSRRFKMAEMIDRWSGELEARTLAKTCYLTIDSAFPQFP---------GAEMWNPPGAISEDCLNMNIWVP-----EDHDGSVMVWIYGGGFFSGTPSLDLYSGSVFAAKEHTIVVNVNYRLGPFGFLYFGDDSPIQGNMGLMDQQLALRWVHENIGAFGGDRSRVTLFGESAGSASTTAHLFAPNSHKYFRNIIAKSGSIINSWASATPPTMLDLSFRLAKKV------------NCSSPDMNAIVKCLRSVPAHLVQAEADNISGDIGPPMTFAYVPVSSDANFFQGDVFQKLANKQFKKDVNIIFGSVKDEGTYWLPYYMSLPKYGFAFNHTISAEDPHNRALITRDHYEESMRAFMPYFAGSKLVLNAFMNSYEHVSTSNVPEERYR--DGVARFLGDLFFTCSLIDFADLISDNIFGNVYMYYFTYRSSANP--WPKWMGVMHGYEIEYAFGQPYWRPHLYDQTHLEDEKRLSSIIMQIWANFANTGRTDSFWPQYNKIERKAIELGE 556
BLAST of Carboxylic ester hydrolase vs. Ensembl Celegans
Match: ace-4 (Carboxylic ester hydrolase [Source:UniProtKB/TrEMBL;Acc:G5EDN1]) HSP 1 Score: 157.147 bits (396), Expect = 1.075e-40 Identity = 141/510 (27.65%), Postives = 225/510 (44.12%), Query Frame = 3
Query: 222 GLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQ----LPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPN-IDVDNHKMIDNKYF----TQTFQYYPHFPIICSQSTRKKISVEYVLNEPSLS---------IDILDRIIADQYFISGSIELANLIS-----KSNS------KVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYL--TQQSETRQSATSIKIMKEFGNFVKHG 1655
G ++G L + I F +P+ +P + + RF+KP+ + RG +D P +N E W + E+ LY+N+W P + N V+VW +GGG+ SGS SL IYDG L S +N+IVV+ NYR+ GF+ L GN+G+ DQ AL W+ +NI F GNP V + G SAG S+ HL+ S F+NAI+ SG + W + R+K+ K+LE + + T + +A ++ + + L F D E F + + + +EG Y+ I + P D + ++ F +TF P II S + +Y+ ++P+ + +++I+ D +F S+ LA+ KS+S KV+ F + WP W G MH EI Y+FG L ++ + R+ S KIM+ + +F K+G
Sbjct: 34 GDIKGTEFFFLSKKIRTFFGVPFAEPAVEDFRFRKPREKKQW------RGLYDATKPANACFQTRDNYNTSFWGSEMWNANTQISEDCLYLNIWAPADAY----NLTVMVWFFGGGFYSGSPSLSIYDGKALTSTQNVIVVNINYRLGPFGFLYLGHPDAPGNMGLLDQQLALHWVRQNIVSFGGNPDKVAVFGQSAGAASIVAHLIAPGSRGLFKNAILQSGSLENTWAINSPF----RAKQKSEKLLE-----LVGCNKTTVDTSMACLRLVSPEQLSLSTWNISLTYLEFPFVIVSRDKHFFGHLDAHAALREGDFNRDVNLMIGMNKDEGNYWNIYQLPQFFDKADPPELNRTEFDFLIDRTFSIQPD--IIRS-------AAKYIYSDPNCTDHGRKTRFYAGQMNQIVGDYFFSCDSLWLADQFRSIPRVKSSSPQRKPGKVFVYHFTQSSSANPWPKWTGAMHGYEIEYVFGIPLSYSKNYKRREQIFSRKIMQFWASFAKNG 515
BLAST of Carboxylic ester hydrolase vs. Ensembl Celegans
Match: ace-3 (Carboxylic ester hydrolase [Source:UniProtKB/TrEMBL;Acc:Q9U295]) HSP 1 Score: 145.976 bits (367), Expect = 5.968e-37 Identity = 130/471 (27.60%), Postives = 212/471 (45.01%), Query Frame = 3
Query: 222 GLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGEN------LDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGI--LQFAWA-PCVDGELIKD-DPRRLFNEKKFKICPTIFLNV-ANEGTY---FIISRF-------PNIDVDN-HKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVLNEPSLS---------IDILDRIIADQYFISGSIELAN---LISKSNSKVYYLWFETFTQPEHWPNWCG 1532
G V+G ++ + FL +P+ +PPI E RF+KP P ++ +I C F G + E W E+ LYVN+W P + N VLVW++GGG+ GS SL +YDG LA++ N+IVV+ NYR+ G++ LD E + GN+G+ DQ AL WI ++I F GNP +++VG SAG S+ HL+ S FQN I+ SG + W D K+A K D +IT + L+N + L+D G+ L+F +A D K D E + + + +EG + + +++F P +D D H+ +D + Q P + + + +YV ++P + + +++++ D +F SI A+ ++ + S V+ +F+ + WP W G
Sbjct: 39 GTVRGTESDHGNKRVRSFLGVPFAEPPINEHRFKKPTPARPWNGTISANTLSPAC--------FQGRDSYDPTFWGSEMWNANTPVSEDCLYVNIWAPADAY----NLTVLVWLFGGGFWYGSPSLLLYDGKELATRGNVIVVNINYRVGPFGYLFLDHEDVPGNMGMLDQQLALYWIRDHIFSFGGNPARISLVGESAGAASIVAHLIAPASKGLFQNGILQSGSLDNKWSM-------DSPKRAKQKSTALADLVGCNQTKITDQTAC-----LRNTP-AQLLIDNIWNVGLNFLEFPFAIVSKDQNFFKHLDGFIALREGTYSTDVNLMFGINHDEGNFWNIYNLAKFFDKQSVKPGLDRDEFHECVDTAFAVQ--------PELV------RTAAKYVYSDPKCTDPKKKTDFYTEQVNQMVGDYFFTCDSIWFAHNYPKMAGNQSNVFVYYFDQPSSANPWPKWTG 470
BLAST of Carboxylic ester hydrolase vs. Ensembl Fly
Match: Ace (gene:FBgn0000024 transcript:FBtr0335223) HSP 1 Score: 204.912 bits (520), Expect = 2.018e-57 Identity = 153/587 (26.06%), Postives = 262/587 (44.63%), Query Frame = 3
Query: 201 LNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEI-LKEKENQ-----------------------------PVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILN-------GNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDT-ELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPN-IDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVL---NEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETR--QSATSIKIMKEFGNFVKHGNLS---EVFRNYDESSNAYIKINED----------LWTSAIFSKDQINKVRFWEKLRR 1790
L S+G V+G++ V R++ + IPY KPP+ +LRF+KP P + +++ + Q F G + EE W P E+ LY+NVW P + L+ P+L+WIYGGG+++GS++L+IY+ ++A+ N+IV SF YR+ GF+ L E+ + GN+G+WDQ A++W+ +N F GNP+ +T+ G SAG SV+ L+ + + +M SG + W +T + + K +N N + + N ++ +++++ K + +GIL F AP +DG + DP L K + NV +EGTYF++ F + D D+ + + + + +Q+ R+ I +Y N + + R + D +F + E A +++ + V+Y +F T W W GV+H +EI Y FG L + R + +++ F K GN + E + N+ + Y + D L F D + KVR W + +
Sbjct: 43 LVVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPW-HGVLDATRLSATCVQERYEYFPGFS-GEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDC--------NCNASMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMN---NIFGKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGEEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKVRSWAEFAQ 616
BLAST of Carboxylic ester hydrolase vs. Ensembl Fly
Match: Ace (gene:FBgn0000024 transcript:FBtr0082780) HSP 1 Score: 204.912 bits (520), Expect = 2.318e-57 Identity = 155/583 (26.59%), Postives = 261/583 (44.77%), Query Frame = 3
Query: 201 LNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEI-LKEKENQ-----------------------------PVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILN-------GNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDT-ELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPN-IDVDNHKMID-NKYFTQTFQYYPHFPIICSQSTRKKISVEYVL---NEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETR--QSATSIKIMKEFGNFVKHGNLS---EVFRNYDESSNAYIKINED----------LWTSAIFSKDQINKVRFW 1775
L S+G V+G++ V R++ + IPY KPP+ +LRF+KP P + +++ + Q F G + EE W P E+ LY+NVW P + L+ P+L+WIYGGG+++GS++L+IY+ ++A+ N+IV SF YR+ GF+ L E+ + GN+G+WDQ A++W+ +N F GNP+ +T+ G SAG SV+ L+ + + +M SG + W +T + + K +N N + + N ++ +++++ K + +GIL F AP +DG + DP L K + NV +EGTYF++ F + D D+ + +KY + +Q+ R+ I +Y N + + R + D +F + E A +++ + V+Y +F T W W GV+H +EI Y FG L + R + +++ F K GN + E + N+ + Y + D L F D + KVR W
Sbjct: 43 LVVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPW-HGVLDATRLSATCVQERYEYFPGFS-GEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDC--------NCNASMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGK----ATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGEEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKVRSW 611
BLAST of Carboxylic ester hydrolase vs. Ensembl Fly
Match: Ace (gene:FBgn0000024 transcript:FBtr0300486) HSP 1 Score: 204.912 bits (520), Expect = 2.318e-57 Identity = 155/583 (26.59%), Postives = 261/583 (44.77%), Query Frame = 3
Query: 201 LNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEI-LKEKENQ-----------------------------PVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILN-------GNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDT-ELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPN-IDVDNHKMID-NKYFTQTFQYYPHFPIICSQSTRKKISVEYVL---NEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETR--QSATSIKIMKEFGNFVKHGNLS---EVFRNYDESSNAYIKINED----------LWTSAIFSKDQINKVRFW 1775
L S+G V+G++ V R++ + IPY KPP+ +LRF+KP P + +++ + Q F G + EE W P E+ LY+NVW P + L+ P+L+WIYGGG+++GS++L+IY+ ++A+ N+IV SF YR+ GF+ L E+ + GN+G+WDQ A++W+ +N F GNP+ +T+ G SAG SV+ L+ + + +M SG + W +T + + K +N N + + N ++ +++++ K + +GIL F AP +DG + DP L K + NV +EGTYF++ F + D D+ + +KY + +Q+ R+ I +Y N + + R + D +F + E A +++ + V+Y +F T W W GV+H +EI Y FG L + R + +++ F K GN + E + N+ + Y + D L F D + KVR W
Sbjct: 43 LVVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPW-HGVLDATRLSATCVQERYEYFPGFS-GEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDC--------NCNASMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGK----ATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGEEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKVRSW 611
BLAST of Carboxylic ester hydrolase vs. Ensembl Fly
Match: clt (gene:FBgn0000326 transcript:FBtr0071687) HSP 1 Score: 145.591 bits (366), Expect = 6.761e-37 Identity = 85/243 (34.98%), Postives = 140/243 (57.61%), Query Frame = 3
Query: 213 VSNGLVQGQTRKVLHR-DIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKK 938
V G++ G+ +K+++ + FL +PY +PP+GELRF+ P+P F K ++ K Q + + + E+ L++NV+ P ++ + PV+VWI+GGG+ G+ + + + + L +E +IVV+ NYR+ LGF+SL +E ++GN+G+ DQ AL+W+ ENI+ F G+P NVT+ G SAGG SV LH + F AIM SG +W F +NE ++++
Sbjct: 24 VKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQ------------RDPFTLEVAGSEDCLFLNVYAP-KVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQE-VIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVF--QNEAPAKTRR 250
BLAST of Carboxylic ester hydrolase vs. Ensembl Fly
Match: alpha-Est2 (gene:FBgn0015570 transcript:FBtr0310421) HSP 1 Score: 137.502 bits (345), Expect = 4.901e-34 Identity = 90/229 (39.30%), Postives = 134/229 (58.52%), Query Frame = 3
Query: 222 GLVQGQTRKVLH--RDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILN--GNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDW 896
G V+G RK ++ F IPY KPP+G+LRF+ PQP + + ++N + P Q M + E E+ L++NV+ ++ LK ++ PV+VWIYGGG+ G +S +IY K+ ++ V+ NYR+A LGF+SL D L+ GN G+ DQV AL+WI +NI+HF G+P N+T++G SAG SV + + E++ F AIM SG LS+W
Sbjct: 40 GQVRGLQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPW-QGVLNCTTNRSKPMQRNMLLGIVEG------------SEDCLHLNVY--VKALKSEKPLPVIVWIYGGGFQKGEASRDIYSPDYFM-KKPVVFVAINYRLAALGFLSLKDPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAIMQSGCALSEW 252
BLAST of Carboxylic ester hydrolase vs. Ensembl Zebrafish
Match: ache (acetylcholinesterase [Source:NCBI gene;Acc:114549]) HSP 1 Score: 212.616 bits (540), Expect = 4.146e-60 Identity = 166/526 (31.56%), Postives = 250/526 (47.53%), Query Frame = 3
Query: 222 GLVQGQTRKVLHRD-IAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKF--------DTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEI-LNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELV----TGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQY-YPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIAD-------QYFISGSIELANLISKSNS-----------------------KVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQ--SETRQSATSIKIMKEFGNFVKHGN 1658
G VQG V R + FL IPY +PPIG+ RF++ +P ++ ++ +F DT P P E W P E+ LY+NVW P +N V+VWIYGGG+ SGSSSL++YDG LA E ++VVS NYR+ GF++L+ GN+G++DQ ALQW+ ENI F GNPK VTI G SAG SV +H+L S F AI+ SGV + W +T +E R R+ K + K++ T N +I L+N + +E L+D E + + +F++ P VDG D P + + FK + +EG+YF++ P DN +I + F ++ + PH I ++ + + N + D +D I+ D Q+F + A L ++S++ VY F+ WP W GV+H EI ++FG L ++ + S +IM+ + NF + GN
Sbjct: 36 GRVQGTRLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEPKKPWN-NVFEAKEFSNACYQFVDTSYPGFP---------GIEMWNPNRVMSEDCLYLNVWVP--PTPRPQNLTVMVWIYGGGFYSGSSSLDVYDGRYLAYTEKVVVVSMNYRVGAFGFLALNGSSDAPGNVGLYDQRLALQWVQENIHFFGGNPKQVTIFGESAGAASVGMHVLSPDSRPLFTRAILQSGVPNTPWATVTFDEARRRTTK-LGKLV-----------GCTWGNDTELIDCLRNKHPQE-LIDQEWQVLPWSSLFRFSFVPVVDGVFFPDTPDAMISSGNFKYTQILLGVNQDEGSYFLLYGAPGFSKDNESLISREDFLESVKMGVPHANDIGLEAVILQYTDWMDENNGQKNRDAMDDIVGDQNVICPLQHFAKSYAQYAALHAQSSAAAPGTLGWGNSGPTGYNSGNSHGAVYLYLFDHRASNLAWPEWMGVIHGYEIEFVFGLPLEKRLNYTAEEEKLSRRIMRYWANFARTGN 536
BLAST of Carboxylic ester hydrolase vs. Ensembl Zebrafish
Match: nlgn4xa (neuroligin 4 X-linked a [Source:ZFIN;Acc:ZDB-GENE-100309-2]) HSP 1 Score: 194.897 bits (494), Expect = 1.046e-52 Identity = 151/458 (32.97%), Postives = 229/458 (50.00%), Query Frame = 3
Query: 264 IAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQL---------PMRIFNGENLDEE-TWIPKERQDENSLYVNVWCPLEILKEKEN--QPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMID-NKY------FTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG 1568
+ ++L IPY PP GE RFQ P+P S+ I N +F PQ + ++ NLD T++ + Q E+ LY+N++ P E EN +PV+V+I+GG Y+ G+ ++ DGS+LAS N+IVV+ NYR+ +LGF+S D+ GN G+ DQ+ AL+WI ENI FKG+PK VTI G+ AG VSL L S + FQ AI+ SG LS W V + K + EK M + I +++ LQN N+KE L++ + A+ P +DG++I DDP+ L + +F + I L V N+G F +F + VD+ + N + F YP + R+ I Y P L + D +++ ++ A+L ++ S Y+ F Q E P+W H +E+ Y+FG
Sbjct: 67 VEQYLGIPYALPPTGERRFQPPEPPMSW-PGIRNATQFAPVCPQFLEDRFLLNDMLPVWFTANLDTVVTYV--QDQSEDCLYLNIYVPTEDDIHDENGLRPVMVYIHGGSYMEGTGNM--IDGSILASYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIKENIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWA------VNYQPAKYTRILAEKVGCNML--------DSIDLVECLQNKNYKE-LIEQYITQAKYHIAFGPVIDGDVIPDDPQILMEQGEF-LNYDIMLGV-NQGEGF---KFVDGIVDSEDGVSANDFDFAVSDFVDHLYGYPE----GKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWSDSAHGDEVPYVFG 495
BLAST of Carboxylic ester hydrolase vs. Ensembl Zebrafish
Match: nlgn4xb (neuroligin 4 X-linked b [Source:ZFIN;Acc:ZDB-GENE-100309-1]) HSP 1 Score: 189.119 bits (479), Expect = 8.677e-51 Identity = 156/501 (31.14%), Postives = 243/501 (48.50%), Query Frame = 3
Query: 144 ICNLIC---LDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKF-DTCPPQLPMRIFNGE--------NLDE-ETWIPKERQDENSLYVNVWCPLEILKEKEN--QPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNIDVDNHKMIDNKY------FTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG 1568
I ++ C L ++ + F N+ GL ++L + +FL +PY P GE RFQ P+P S+ I N +F CP L R+ + NLD T++ Q E+ LY+N++ P E + + +PV+V+I+GG YV G+ ++ DGSVLAS N+IVV+ NYR+ +LGF+S D+ GN G+ DQ+ AL+W+ ENI F G+P+ VTI G+ AG VSL L S + FQ AI+ SG LS W V + K + EK + NE+ T E +I+ LQ+ N+KE L++ + A+ P +DG++I DDP+ L + +F + I L V EG F+ + D ++ N + F YP + R+ I Y P + L + D +++ ++ A+L ++ S Y+ F Q + P W H +E+ Y+FG
Sbjct: 5 ILSVFCGFTLALAQQTQFITVTTNYGKLRGLRVALPSEIL-GPVEQFLGVPYAMAPTGERRFQAPEPPLSW-PGIRNATQFAPVCPQFLEDRLLLTDMLPVWFTANLDTVATYV--HDQSEDCLYLNIYVPTEEETQDDAGLKPVMVYIHGGSYVEGTGNM--IDGSVLASYGNVIVVTVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWVKENIQSFSGDPERVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWA------VNYQPAKYTRLLAEK----VGCNEDDTLE----LIECLQSKNYKE-LIEQNITPAKYHIAFGPVIDGDVIPDDPQILMEQGEF-LNYDIMLGVNQGEGYKFVDGILDSED----RVTSNDFEFAISEFVDHLYGYPE----GKDTLRETIKFMYTDWADRENPEMRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSDMKPAWADSSHGDELPYVFG 475
BLAST of Carboxylic ester hydrolase vs. Ensembl Zebrafish
Match: nlgn4xb (neuroligin 4 X-linked b [Source:ZFIN;Acc:ZDB-GENE-100309-1]) HSP 1 Score: 189.119 bits (479), Expect = 8.677e-51 Identity = 156/501 (31.14%), Postives = 243/501 (48.50%), Query Frame = 3
Query: 144 ICNLIC---LDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKF-DTCPPQLPMRIFNGE--------NLDE-ETWIPKERQDENSLYVNVWCPLEILKEKEN--QPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNIDVDNHKMIDNKY------FTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG 1568
I ++ C L ++ + F N+ GL ++L + +FL +PY P GE RFQ P+P S+ I N +F CP L R+ + NLD T++ Q E+ LY+N++ P E + + +PV+V+I+GG YV G+ ++ DGSVLAS N+IVV+ NYR+ +LGF+S D+ GN G+ DQ+ AL+W+ ENI F G+P+ VTI G+ AG VSL L S + FQ AI+ SG LS W V + K + EK + NE+ T E +I+ LQ+ N+KE L++ + A+ P +DG++I DDP+ L + +F + I L V EG F+ + D ++ N + F YP + R+ I Y P + L + D +++ ++ A+L ++ S Y+ F Q + P W H +E+ Y+FG
Sbjct: 5 ILSVFCGFTLALAQQTQFITVTTNYGKLRGLRVALPSEIL-GPVEQFLGVPYAMAPTGERRFQAPEPPLSW-PGIRNATQFAPVCPQFLEDRLLLTDMLPVWFTANLDTVATYV--HDQSEDCLYLNIYVPTEEETQDDAGLKPVMVYIHGGSYVEGTGNM--IDGSVLASYGNVIVVTVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWVKENIQSFSGDPERVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWA------VNYQPAKYTRLLAEK----VGCNEDDTLE----LIECLQSKNYKE-LIEQNITPAKYHIAFGPVIDGDVIPDDPQILMEQGEF-LNYDIMLGVNQGEGYKFVDGILDSED----RVTSNDFEFAISEFVDHLYGYPE----GKDTLRETIKFMYTDWADRENPEMRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSDMKPAWADSSHGDELPYVFG 475
BLAST of Carboxylic ester hydrolase vs. Ensembl Zebrafish
Match: nlgn4xb (neuroligin 4 X-linked b [Source:ZFIN;Acc:ZDB-GENE-100309-1]) HSP 1 Score: 189.119 bits (479), Expect = 8.677e-51 Identity = 156/501 (31.14%), Postives = 243/501 (48.50%), Query Frame = 3
Query: 144 ICNLIC---LDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKF-DTCPPQLPMRIFNGE--------NLDE-ETWIPKERQDENSLYVNVWCPLEILKEKEN--QPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNIDVDNHKMIDNKY------FTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG 1568
I ++ C L ++ + F N+ GL ++L + +FL +PY P GE RFQ P+P S+ I N +F CP L R+ + NLD T++ Q E+ LY+N++ P E + + +PV+V+I+GG YV G+ ++ DGSVLAS N+IVV+ NYR+ +LGF+S D+ GN G+ DQ+ AL+W+ ENI F G+P+ VTI G+ AG VSL L S + FQ AI+ SG LS W V + K + EK + NE+ T E +I+ LQ+ N+KE L++ + A+ P +DG++I DDP+ L + +F + I L V EG F+ + D ++ N + F YP + R+ I Y P + L + D +++ ++ A+L ++ S Y+ F Q + P W H +E+ Y+FG
Sbjct: 5 ILSVFCGFTLALAQQTQFITVTTNYGKLRGLRVALPSEIL-GPVEQFLGVPYAMAPTGERRFQAPEPPLSW-PGIRNATQFAPVCPQFLEDRLLLTDMLPVWFTANLDTVATYV--HDQSEDCLYLNIYVPTEEETQDDAGLKPVMVYIHGGSYVEGTGNM--IDGSVLASYGNVIVVTVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWVKENIQSFSGDPERVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWA------VNYQPAKYTRLLAEK----VGCNEDDTLE----LIECLQSKNYKE-LIEQNITPAKYHIAFGPVIDGDVIPDDPQILMEQGEF-LNYDIMLGVNQGEGYKFVDGILDSED----RVTSNDFEFAISEFVDHLYGYPE----GKDTLRETIKFMYTDWADRENPEMRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSDMKPAWADSSHGDELPYVFG 475
BLAST of Carboxylic ester hydrolase vs. Ensembl Xenopus
Match: nfasc (neurofascin [Source:Xenbase;Acc:XB-GENE-922969]) HSP 1 Score: 255.373 bits (651), Expect = 1.606e-76 Identity = 176/502 (35.06%), Postives = 263/502 (52.39%), Query Frame = 3
Query: 219 NGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQP----VLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELV-----TGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVL---------NEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQ-SETRQSAT-SIKIMKEFGNFVKHGN 1658
+G V+G VL + FL IPY +PP+G+LRF+KP P S+S ++ K+ Q+P F G + E W P E+ LY+NVW P + QP V+VWIYGGG+V+G+SSL++YDG LA+ E +IVVS NYR+ LGF+S+ + GN+G++DQ AL+WI+ENI+ F GNP+++TI G SAG SVS HLL KS YF AIM SG + WG + K E R R+ N++ ++ +NK II L+ KE + V I++ + P VDG+ + + P +L + K I V +EG+YF++ P D+ I+ F ++ + FP +++VE +L P+L D +D ++ D FI +E S VY +F+ + WP W GV+H EI ++FG L ++ + T+Q T S +M+++ NF K GN
Sbjct: 36 HGKVKGVQIPVLSGTVTAFLGIPYAEPPVGDLRFKKPNPPKSWS-DVLYASKYGNSCFQIPDETFPGFS-GAEMWNPNTEVSEDCLYLNVWVP-------DPQPTGVSVMVWIYGGGFVTGTSSLDVYDGKFLAAVEQVIVVSMNYRLGALGFLSIPGNADAPGNVGLFDQRLALEWIYENIATFGGNPQSITIFGESAGAASVSYHLLSPKSHPYFTRAIMQSGSANAPWGAINKTEARHRALILANQLGCSYE----------TDNK--IIACLRGKTPKEISDKADYVIPPGDRAIIEMTFPPSVDGDFLTEMPEQLLQLGQLKKNTQILTGVNKDEGSYFLVYGMPGFSKDHDSYINRTQFEESVRL--SFP------KAAELAVESILFYYADWEGVRNPALYRDAMDDVVGDYNFICPLLEFTKRASHLGDNVYLYFFQHRSSQLAWPEWMGVIHGYEIEFVFGKPLDEKLNYTKQEETLSRAVMRQWANFAKTGN 508
BLAST of Carboxylic ester hydrolase vs. Ensembl Xenopus
Match: ENSXETT00000046462.1 (butyrylcholinesterase [Source:NCBI gene;Acc:100495889]) HSP 1 Score: 238.039 bits (606), Expect = 1.418e-69 Identity = 167/495 (33.74%), Postives = 247/495 (49.90%), Query Frame = 3
Query: 222 GLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELV---TGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVL---------NEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG--HYLTQQSETRQSATSIKIMKEFGNFVKHGN 1658
G V G V I FL IPY +PPIG+LRF+KP P +S+ I N ++ Q +IF G + E W P + E+ LY+N+W P + N V+VWIYGG + +G+SSL++YDG LA E +IVVS NYR+ LGF++ + GN+G++DQ ALQW++ENI+ F GNPK++TI G SAGG SVS H+L KS +F AIM S + W +TK E +R+ N +L F N+ II L+N + +E V +++ + P VDG+ + + P L + K I V +EG+YF++ P D+ I+ F ++ + FP +++++ VL PS + D +D I+ D FI +E S+ + Y +F + WP W GVMH EI ++FG Y + S +M+ + NF K GN
Sbjct: 38 GKVTGVQISVFSGIITAFLGIPYAEPPIGDLRFKKPVPHKPWSE-IWNASQYGNSCYQTVDQIFPGFS-GAEMWNPNTQLSEDCLYLNIWIPT---PKPRNASVMVWIYGGSFETGTSSLDLYDGKFLARTERVIVVSMNYRLGALGFLAFPGNNEAPGNVGLFDQRLALQWVYENIAAFGGNPKSITIFGESAGGASVSYHMLSPKSHGFFTRAIMQSATANAPWAVITKAEASNRALTLAN-LLNCF-----------YRNETEIIACLRNKSPEEIFEKAVSVLPHRSVIEVNFPPTVDGDFLIEMPEILMQLGQLKKKTQILTGVNKDEGSYFLVYGLPGFSKDHESFINRTQFHKSVKL--AFP------KATELAIDSVLFHYTNWEDEQNPSHNRDAMDDIVGDYNFICPLLEFTKWNSELGNNAYLYYFHHRSSKLTWPGWMGVMHGYEIEFVFGIPMYRRLNYTKAEETLSRTLMRYWANFAKTGN 507
BLAST of Carboxylic ester hydrolase vs. Ensembl Xenopus
Match: ACHE (acetylcholinesterase (Cartwright blood group) [Source:NCBI gene;Acc:100490673]) HSP 1 Score: 219.935 bits (559), Expect = 7.230e-63 Identity = 155/510 (30.39%), Postives = 247/510 (48.43%), Query Frame = 3
Query: 210 SVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQP-------FSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILN--GNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTEL----VTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVLNEPSLSID---------ILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQ--QSETRQSATSIKIMKEFGNFVKHGNLSE 1667
S +G V+G + VL ++ FL IP+ +PP+ ++RF++ +P + + + FDT P P E W P E+ LY+N+W P N V+VWIYGGG+ SGSSSL++YDG L EN+IVVS NYR+ GF++L ++ GN+G++DQ ALQW+ +NI+ F G+P+ VTI G SAG SV +H+L S F A + SG + W +T E R R+ ++L KF + N ++ L+ +E L+D E + +FA+ P D + + P L N +FK CP I NEG+YF++ P +N +I + F + S I++E V+ + + D +D+++ D I A ++++ ++VY +F+ WP W GV H EI ++FG L ++ A S ++M+ + NF + G+ +E
Sbjct: 32 STRSGKVRGLRQPVLSTHVSAFLGIPFAEPPVDKMRFRRSEPKKPWTDVWDATAYPNACYQYFDTLYPGFP---------GMEMWNPNRPMSEDCLYLNIWVPH---PRPSNATVMVWIYGGGFYSGSSSLDVYDGRYLCHAENVIVVSMNYRVGAFGFLTLTPGSVDAPGNVGLFDQRLALQWVQDNIAFFGGDPRTVTIFGESAGAVSVGMHVLSPGSHHLFSKAALQSGSPNTPWATITPQEARRRT-----ELLGKF-------LDCRMGNDTELLNCLRVKQPQE-LIDHEFSVLPAPSVFRFAFVPVPDADFFPEPPEILMNMGRFKPCPLIMGVNQNEGSYFLLYGAPGFSKNNESLITREEFLGG--------VKMSVPQANDIALEAVVMQYTDWADEHAGVKNREAMDQLVGDHNVICPLTYFAGKVAETGNRVYTYFFDHRASNLAWPQWMGVPHGYEIEFVFGLPLDANLNYTPQEEALSRRMMRYWANFARTGDPNE 508
BLAST of Carboxylic ester hydrolase vs. Ensembl Xenopus
Match: nlgn4x (neuroligin 4 X-linked [Source:NCBI gene;Acc:100329189]) HSP 1 Score: 193.741 bits (491), Expect = 2.802e-52 Identity = 153/490 (31.22%), Postives = 233/490 (47.55%), Query Frame = 3
Query: 264 IAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKF-DTCPPQLPMR--------IFNGENLDEETWIPKERQDENSLYVNVWCPLE--ILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNIDVDNHKMIDNKY--FTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSE-------TRQSATSIKIMKEFGNFVKHGN 1658
+ ++L +PY PP GE RFQ P+P SS++ I N +F CP L R I+ NLD ++ Q+E+ LY+N++ P E I +PV+V+I+GG Y+ G+ ++ DGS+LAS N+IV++ NYR+ +LGF+S D+ GN G+ DQ+ AL+WI ENI F G+PK VTI G+ AG VSL L S FQ AI+ SG LS W V + K + +K M + I +++ L++ N+KE L+ + A+ P +DG++I DDP+ L + +F + I L V EG F+ N D + D F YP + R+ I Y P L + D +++ ++ A+L ++ S Y+ F Q E P W H +E+ Y+FG + +E S +M + NF K G+
Sbjct: 70 VEQYLGVPYASPPTGERRFQPPEPPSSWT-GIKNATQFAPVCPQFLDERSLLNDMLPIWFTANLDTVVSYVQD-QNEDCLYLNIYVPTEDDIHDPNNKKPVMVYIHGGSYMEGTGNM--IDGSILASHGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIEENIGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWA------VNYQPAKYTRILADKVGCDML--------DTIDLVECLRDKNYKE-LIQQSITPATYHIAFGPVIDGDVIPDDPQILMEQGEF-LNYDIMLGVNQGEGLKFVDGMVDNEDGVSLSDFDFSVSNFVDNLYGYPE----GKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHARYGSPTYFYAFYHHCQSEMKPTWADSAHGDEVPYVFGIPMIGPTELFNCNFSKNDVMLSAVVMTYWTNFAKTGD 535
BLAST of Carboxylic ester hydrolase vs. Ensembl Xenopus
Match: ENSXETT00000017385.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:8:101032049:101036224:1 gene:ENSXETG00000008778.1 transcript:ENSXETT00000017385.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 186.037 bits (471), Expect = 6.954e-51 Identity = 162/567 (28.57%), Postives = 264/567 (46.56%), Query Frame = 3
Query: 141 FICNLICLDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVT----GILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVA-NEGTYFIISRFPNIDVDNHKMIDNKYFTQTF-QYYPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNLSEVFRNYD--ESSNAYIKINEDLWTSAIFSKDQINKVRFWEKLRRKFYDNF 1808
F CNL+ + + + + + V G V G V + +L IPY +PP G LRF+K + + ++ KF Q F E E ++ E+ L++NVW P K+ V+V+I+GGG+ SG++SL+IYDGSVLA EN+IVVS NYR+ GF++L + GN G++DQ ALQWI+ENI+ F GNP VTI G+SAG SV HL+ KS+ Y+ AI+ SG S+W ++ +R+K+ K+ E + P + + AII L N + K L + +L+ + QF P VD + + D P + + + I L + ++G F + + ++ I + + +++P + QS + +N + ++ I+ D YF A + + V++ ++ + + WP W G +H E+ LFG + +S S +IMK + NF + G V+ Y + A +K+N S + + +FW NF
Sbjct: 11 FFCNLLMSFLILSTNAGHENI-VEVKQGKVSGINLSVKSGYVTAYLGIPYGEPPTGRLRFKKTEQRKPW-HGVLKADKFGKSCFQNRENKF-AEFPGTEMFLVNNEMSEDCLHLNVWVPPSKPKDAH---VMVFIHGGGFESGTTSLDIYDGSVLAYAENVIVVSMNYRVGAFGFLALPGHKDAPGNAGLFDQRLALQWINENIAAFGGNPDRVTIFGHSAGAASVGFHLISTKSYPYYNRAIVQSGSGTSNWALNSE----ERAKRLALKLAEVLECP--------QTDDDAIITCLLNEDPKH-LTEKQLLAKEPYALTQF--LPIVDHDFLVDVPENVLGQSMKRT--DILLGITKDDGNPFTLIGSTDFNIQTESSISSAELLERLKRFFPSAGDLGIQSILLQYKDWEDVNNGEKNRQAMELILRDYYFACPVKGFARYAVEHQNNVFFYEYDHRSSNDPWPEWMGALHGAELPMLFGKPFINKGRYTRSELLFSKRIMKLWANFARTGYNGFVWPQYSLKDEKYAVLKLN----GSEVHQMLSMRNCQFWNFFFPSLLKNF 550
BLAST of Carboxylic ester hydrolase vs. Ensembl Mouse
Match: Bche (butyrylcholinesterase [Source:MGI Symbol;Acc:MGI:894278]) HSP 1 Score: 262.307 bits (669), Expect = 7.605e-79 Identity = 187/558 (33.51%), Postives = 286/558 (51.25%), Query Frame = 3
Query: 153 LICLDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELV---TGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV--LNE--PSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNL------SEVFRNYDESSNAYIKINEDLWTSAIFSKDQINKVRFWE 1778
L+C+ K H T++ + G V+G + VL + FL IPY +PP+G LRF+KPQP + + I N ++ Q + F G E W P E+ LY+NVW P+ + +N V+VWIYGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++ + GN+G++DQ ALQW+ NI+ F GNPK++TI G SAG SVSLHLL +S+ F AI+ SG + W E R+R+ L KF ++EN++ +IK L++ + +E L + V IL + P VDG+ + D P L K K + +EGT F++ P DN +I K F + Y FP + S+ ++ + YV L E P + D LD +I D I ++E ++ + ++ +FE + WP W GVMH EI ++FG L ++ ++ S IMK + NF K+G+ S ++ + + Y+ +N + S I+SK + + +FW
Sbjct: 19 LLCMPFG-KSH-TEEDFIITTKTGRVRGLSMPVLGGTVTAFLGIPYAQPPLGSLRFKKPQPLNKWP-DIHNATQYANSCYQNIDQAFPGFQ-GSEMWNPNTNLSEDCLYLNVWIPV---PKPKNATVMVWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLAFPGNPDAPGNMGLFDQQLALQWVQRNIAAFGGNPKSITIFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKHPEEARNRT-----LTLAKFT-------GCSKENEMEMIKCLRSKDPQEILRNERFVLPSDSILSINFGPTVDGDFLTDMPHTLLQLGKVKKAQILVGVNKDEGTAFLVYGAPGFSKDNDSLITRKEFQEGLNMY--FPGV-SRLGKEAVLFYYVDWLGEQSPEVYRDALDDVIGDYNIICPALEFTKKFAELENNAFFYFFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLGRRVNYTRAEEIFSRSIMKTWANFAKYGHPNGTQGNSTMWPVFTSTEQKYLTLNTE--KSKIYSKLRAPQCQFWR 552
BLAST of Carboxylic ester hydrolase vs. Ensembl Mouse
Match: Ache (acetylcholinesterase [Source:MGI Symbol;Acc:MGI:87876]) HSP 1 Score: 216.083 bits (549), Expect = 1.624e-61 Identity = 149/516 (28.88%), Postives = 243/516 (47.09%), Query Frame = 3
Query: 213 VSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVT----GILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQY-YPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYL--TQQSETRQSATSIKIMKEFGNFVKHGNL-------SEVFRNYDESSNAYIKIN 1715
V G ++G K ++ FL IP+ +PP+G RF P+P +S +++ F Q ++ G E W P E+ LY+NVW P + PVL+WIYGGG+ SG++SL++YDG LA E ++VS NYR+ GF++L GN+G+ DQ ALQW+ ENI+ F G+P +VT+ G SAG SV +H+L S F A++ SG W ++ E R R+ +L + + N +I L+ ++ L+D E I +F++ P VDG+ + D P L N F+ + V +EG+YF++ P DN +I F + P + +++ + +P+ D + ++ D + +LA ++ ++VY FE WP W GV H EI ++FG L + T + + ++MK + NF + G+ S + Y ++ Y+ +N
Sbjct: 43 VRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWS-GVLDATTFQNVCYQYVDTLYPGFE-GTEMWNPNRELSEDCLYLNVWTPYP--RPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRA-----TLLARL---VGCPPGGAGGNDTELIACLRTRPAQD-LVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLN 545
BLAST of Carboxylic ester hydrolase vs. Ensembl Mouse
Match: Ache (acetylcholinesterase [Source:MGI Symbol;Acc:MGI:87876]) HSP 1 Score: 216.083 bits (549), Expect = 1.624e-61 Identity = 149/516 (28.88%), Postives = 243/516 (47.09%), Query Frame = 3
Query: 213 VSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVT----GILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQY-YPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYL--TQQSETRQSATSIKIMKEFGNFVKHGNL-------SEVFRNYDESSNAYIKIN 1715
V G ++G K ++ FL IP+ +PP+G RF P+P +S +++ F Q ++ G E W P E+ LY+NVW P + PVL+WIYGGG+ SG++SL++YDG LA E ++VS NYR+ GF++L GN+G+ DQ ALQW+ ENI+ F G+P +VT+ G SAG SV +H+L S F A++ SG W ++ E R R+ +L + + N +I L+ ++ L+D E I +F++ P VDG+ + D P L N F+ + V +EG+YF++ P DN +I F + P + +++ + +P+ D + ++ D + +LA ++ ++VY FE WP W GV H EI ++FG L + T + + ++MK + NF + G+ S + Y ++ Y+ +N
Sbjct: 43 VRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWS-GVLDATTFQNVCYQYVDTLYPGFE-GTEMWNPNRELSEDCLYLNVWTPYP--RPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRA-----TLLARL---VGCPPGGAGGNDTELIACLRTRPAQD-LVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLN 545
BLAST of Carboxylic ester hydrolase vs. Ensembl Mouse
Match: Ces2g (carboxylesterase 2G [Source:MGI Symbol;Acc:MGI:1919611]) HSP 1 Score: 182.57 bits (462), Expect = 1.007e-49 Identity = 163/555 (29.37%), Postives = 266/555 (47.93%), Query Frame = 3
Query: 210 SVSNGLVQGQTRKV--LHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDE-ETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLL---DTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISR-------FPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFE---TFTQPEHWPNWCGVMHSEEIYYLFGHY---LTQQSETRQSATSIKIMKEFGNFVKHGNLSE-------VFRNYDESSNAYIKINEDLWTSAIFSKDQINKVRFWEK-LRRK 1793
S +G VQG+ V + FL IP+ KPP+G LRF P+ +S + CP + M N E L E + +P E+ LY+N++ P +E N PV+VWI+GG G +S+ YDGSVLA+ E+++VV+ YR+ +LGF S DE GN G DQV AL+W+ +NI+HF GNP VTI G SAGG SVS H++ S F AIM SGV L + +EV V + + K + E A+++ L+ + +E L + +++ G+ VDGE + P+ L F P+I + N+ +I+ + I +N + + Q P CS ++ +E + + +L I + ++ D F+ S+++A +S++ VY+ F+ +F + + P H +E+ ++FG + + + + ++MK + NF +HGN + VF ++DE Y+++N A+ + K++FW K L RK
Sbjct: 37 STHSGQVQGRLIHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAICPQNVTM---NMEGLKELKLTLPPVSMSEDCLYLNIYTPAHA-QEGSNLPVMVWIHGGALTVGMASM--YDGSVLAATEDVVVVAIQYRLGVLGFFSTGDEHARGNWGFLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGISVSSHVVSPMSKGLFHRAIMESGVALLPGTIFSFSEV-------VYQTVAKLSGCEAMDSE-------ALVRCLRGKSEEEILAISKNFQMIPGV--------VDGEFLPKHPQELLASADFHPVPSI-IGFNNDEYGWIVPKVIGSTQTIKGITRENLQAVLKDTAPQMM-----LPPECSDLLMEEY-MEDIEDPKTLQIQFTE-MMEDFMFVIPSLQVA-YFQRSHAPVYFYEFQHQSSFLK-DVRPPHVNADHGDEVPFVFGSFFWGMKLNLTEEEKLLNRRMMKYWANFARHGNPNSESLPYWPVF-DHDEQ---YLQLN---IQPAVGQFQKARKLQFWTKTLPRK 546
BLAST of Carboxylic ester hydrolase vs. Ensembl Mouse
Match: Nlgn1 (neuroligin 1 [Source:MGI Symbol;Acc:MGI:2179435]) HSP 1 Score: 184.111 bits (466), Expect = 5.711e-49 Identity = 144/486 (29.63%), Postives = 231/486 (47.53%), Query Frame = 3
Query: 264 IAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKF-DTCP--------PQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLE--ILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNIDVDNHKMIDNKY--FTQTFQYYPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSE-------TRQSATSIKIMKEFGNFVKHGN 1658
+ +FL +PY PP GE RFQ P+P S +S I N +F CP P++ + ++ NLD + ++ Q E+ LY+N++ P E I +PV+V+I+GG Y+ G+ +L YDGSVLAS N+IV++ NYR+ +LGF+S D+ GN G+ D + AL+W ENI F G+P +T+ G+ AGG V+L L S FQ AI SG LS W AV+ K+ + + + +++ LQ +KE L+D ++ A+ P +DG++I DDP+ L + +F + I L V EG F+ + + D + D F YP + ++ + + + P L + D +++ ++ A+L S S Y+ F Q + P W H +E+ Y+ G + +E S +M + NF K G+
Sbjct: 77 VIQFLGVPYAAPPTGEHRFQPPEPPSPWS-DIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQD-QSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNL--YDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGLFQRAIAQSGTALSSW--------------AVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKE-LVDQDVQPARYHIAFGPVIDGDVIPDDPQILMEQGEF-LNYDIMLGVNQGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGD 542
BLAST of Carboxylic ester hydrolase vs. UniProt/SwissProt
Match: sp|P81908|CHLE_HORSE (Cholinesterase OS=Equus caballus OX=9796 GN=BCHE PE=1 SV=1) HSP 1 Score: 262.307 bits (669), Expect = 2.449e-78 Identity = 179/538 (33.27%), Postives = 283/538 (52.60%), Query Frame = 3
Query: 210 SVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVT---GILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV--LNEPSLS--IDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQ-SETR-QSATSIKIMKEFGNFVKHGNLSEVFRN------YDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
+ NG V+G VL + FL IPY +PP+G LRF+KPQ + +S +I N K+ Q + F G L E W P E+ LY+NVW P + +N V++WIYGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++L ++ GN+G++DQ ALQW+ +NI+ F GNP++VT+ G SAG SVSLHLL +S F AI+ SG + W + E R+R+ ++ +R+N+ +IK L++ + +E LL+ V +L + P VDG+ + D P L +FK + +EGT F++ P DN+ +I K F + + + FP + S+ R+ I Y+ L++ + LD ++ D I ++E S+ + ++ +FE + WP W GVMH EI ++FG L ++ + TR + S IMK + NF K+GN + N + + Y+ +N + + +++K + + RFW
Sbjct: 7 TTKNGKVRGMNLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWS-NIWNATKYANSCYQNTDQSFPG-FLGSEMWNPNTELSEDCLYLNVWIPA---PKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALSENPEAPGNMGLFDQQLALQWVQKNIAAFGGNPRSVTLFGESAGAASVSLHLLSPRSQPLFTRAILQSGSSNAPWAVTSLYEARNRTLTLAKRM------------GCSRDNETEMIKCLRDKDPQEILLNEVFVVPYDTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKRTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF--FPRV-SEFGRESILFHYMDWLDDQRAENYREALDDVVGDYNIICPALEFTRKFSELGNDAFFYYFEHRSTKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEILSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSTEQKYLTLNTE--SPKVYTKLRAQQCRFW 522
BLAST of Carboxylic ester hydrolase vs. UniProt/SwissProt
Match: sp|Q03311|CHLE_MOUSE (Cholinesterase OS=Mus musculus OX=10090 GN=Bche PE=1 SV=2) HSP 1 Score: 262.307 bits (669), Expect = 5.320e-78 Identity = 187/558 (33.51%), Postives = 286/558 (51.25%), Query Frame = 3
Query: 153 LICLDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELV---TGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV--LNE--PSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNL------SEVFRNYDESSNAYIKINEDLWTSAIFSKDQINKVRFWE 1778
L+C+ K H T++ + G V+G + VL + FL IPY +PP+G LRF+KPQP + + I N ++ Q + F G E W P E+ LY+NVW P+ + +N V+VWIYGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++ + GN+G++DQ ALQW+ NI+ F GNPK++TI G SAG SVSLHLL +S+ F AI+ SG + W E R+R+ L KF ++EN++ +IK L++ + +E L + V IL + P VDG+ + D P L K K + +EGT F++ P DN +I K F + Y FP + S+ ++ + YV L E P + D LD +I D I ++E ++ + ++ +FE + WP W GVMH EI ++FG L ++ ++ S IMK + NF K+G+ S ++ + + Y+ +N + S I+SK + + +FW
Sbjct: 19 LLCMPFG-KSH-TEEDFIITTKTGRVRGLSMPVLGGTVTAFLGIPYAQPPLGSLRFKKPQPLNKWP-DIHNATQYANSCYQNIDQAFPGFQ-GSEMWNPNTNLSEDCLYLNVWIPV---PKPKNATVMVWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLAFPGNPDAPGNMGLFDQQLALQWVQRNIAAFGGNPKSITIFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKHPEEARNRT-----LTLAKFT-------GCSKENEMEMIKCLRSKDPQEILRNERFVLPSDSILSINFGPTVDGDFLTDMPHTLLQLGKVKKAQILVGVNKDEGTAFLVYGAPGFSKDNDSLITRKEFQEGLNMY--FPGV-SRLGKEAVLFYYVDWLGEQSPEVYRDALDDVIGDYNIICPALEFTKKFAELENNAFFYFFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLGRRVNYTRAEEIFSRSIMKTWANFAKYGHPNGTQGNSTMWPVFTSTEQKYLTLNTE--KSKIYSKLRAPQCQFWR 552
BLAST of Carboxylic ester hydrolase vs. UniProt/SwissProt
Match: sp|O62760|CHLE_FELCA (Cholinesterase OS=Felis catus OX=9685 GN=BCHE PE=2 SV=1) HSP 1 Score: 260.381 bits (664), Expect = 2.341e-77 Identity = 186/545 (34.13%), Postives = 286/545 (52.48%), Query Frame = 3
Query: 189 TKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVT---GILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV--LNEPSLS--IDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQ-SETR-QSATSIKIMKEFGNFVKHGNLSEVFRN------YDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
T++ + + NG V+G VL + FL IPY +PP+G LRF+KPQ + +S I N K+ Q + F G E W P E+ LY+NVW P + +N V++WIYGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++L + + GN+G++DQ ALQW+ +NI+ F GNPK+VT+ G SAG SVSLHLL +S F AI+ SG + W ++ +E ++R+ L KF ++EN IIK L+N + +E LL+ LV +L + P VDG+ + D P L +FK + +EGT F++ P DN +I K F + + Y FP + S+ R+ I YV L++ + LD ++ D I ++E S+ + ++ +FE + WP W GVMH EI ++FG L ++ + TR + S IM + NF K+GN + N + + Y+ +N + + +++K + + RFW
Sbjct: 28 TEEDIIITTKNGKVRGMNLPVLDGTVTAFLGIPYAQPPLGRLRFKKPQFLTKWS-DIWNATKYANSCYQNADQSFPGFP-GSEMWNPNTDLSEDCLYLNVWIPT---PKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEVPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAGSVSLHLLSPRSQPLFTRAILQSGSSNAPWAVMSLDEAKNRT-----LTLAKFI-------GCSKENDTEIIKCLRNKDPQEILLNELLVVPSDTLLSVNFGPVVDGDFLTDMPDTLLQLGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNDSIITRKEFQEGLKIY--FPGV-SEFGREAILFYYVDLLDDQRAEKYREALDDVLGDYNIICPALEFTTKFSELGNNAFFYYFEHRSSQLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEILSRSIMNYWANFAKYGNPNGTQNNSTRWPAFRSTDQKYLTLNAE--SPKVYTKLRAQQCRFW 550
BLAST of Carboxylic ester hydrolase vs. UniProt/SwissProt
Match: sp|P06276|CHLE_HUMAN (Cholinesterase OS=Homo sapiens OX=9606 GN=BCHE PE=1 SV=1) HSP 1 Score: 259.61 bits (662), Expect = 4.665e-77 Identity = 188/557 (33.75%), Postives = 284/557 (50.99%), Query Frame = 3
Query: 153 LICLDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGI---LQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNLSEVFRN------YDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
L+C+ I K H T+ + + NG V+G V + FL IPY +PP+G LRF+KPQ + +S I N K+ Q + F G + E W P E+ LY+NVW P + +N VL+WIYGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++L + GN+G++DQ ALQW+ +NI+ F GNPK+VT+ G SAG SVSLHLL S F AI+ SG + W + E R+R+ L K +REN+ IIK L+N + +E LL+ V L + P VDG+ + D P L +FK + +EGT F++ P DN+ +I K F + + + FP + S+ ++ I Y P + L ++ D FI ++E S+ + ++ +FE + WP W GVMH EI ++FG L ++ ++ S I+K + NF K+GN +E N + + Y+ +N + ++ I +K + + RFW
Sbjct: 18 LLCMLIG-KSH-TEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWS-DIWNATKYANSCCQNIDQSFPGFH-GSEMWNPNTDLSEDCLYLNVWIPA---PKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLN-----LAKLT-------GCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF--FPGV-SEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTE--STRIMTKLRAQQCRFW 550
BLAST of Carboxylic ester hydrolase vs. UniProt/SwissProt
Match: sp|P21927|CHLE_RABIT (Cholinesterase OS=Oryctolagus cuniculus OX=9986 GN=BCHE PE=2 SV=1) HSP 1 Score: 258.84 bits (660), Expect = 5.655e-77 Identity = 179/538 (33.27%), Postives = 276/538 (51.30%), Query Frame = 3
Query: 210 SVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVT---GILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNLSEVFRN------YDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
+ NG ++G V + FL IPY +PP+G LRF+KPQ + +S I N K+ Q + F G + E W P E+ LY+NVW P + +N V++WIYGGG+ +G+SSL++YDG L E +IVVS NYR+ LGF++L + GN+G++DQ ALQW+ +NI+ F GNPK+VT+ G SAG SVSLHLL +S F AI+ SG + W ++ +E R+R+ L KF + EN+ IIK L+N + +E LL+ V +L + P VDG+ + D P L + K + +EGT F++ P DN +I K F + + + FP + S+ ++ I Y P + LD ++ D FI ++E S+ + ++ +FE + WP W GVMH EI ++FG L ++ ++ S IMK + NF K+GN + N + + Y+ +N + + I++K + + RFW
Sbjct: 14 TTKNGRIRGINLPVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWS-DIWNATKYANSCCQNIDQSFPGFH-GSEMWNPNTDLSEDCLYLNVWIPT---PKPKNATVMIWIYGGGFQTGTSSLQVYDGKFLTRVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPRSHPLFTRAILQSGSSNAPWEVMSLHEARNRT-----LTLAKF-------VGCSTENETEIIKCLRNKDAQEILLNEVFVVPFDSLLSVNFGPTVDGDFLTDMPDTLLQLGQLKKTQILVGVNKDEGTAFLVYGAPGFSKDNTSIITRKEFQEGLKIF--FPGV-SEFGKESILFHYTDWVDEQRPENYREALDDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTKAEEILSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSTEQKYLTLNTE--SPRIYTKLRAQQCRFW 529
BLAST of Carboxylic ester hydrolase vs. TrEMBL
Match: A0A177B5V2 (Carboxylic ester hydrolase (Fragment) OS=Intoshia linei OX=1819745 GN=A3Q56_02597 PE=3 SV=1) HSP 1 Score: 279.641 bits (714), Expect = 5.582e-82 Identity = 178/507 (35.11%), Postives = 269/507 (53.06%), Query Frame = 3
Query: 186 FTKQMLNFSVSNGLVQGQTRKV--LHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEI-LKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKK-AVNKIL--EKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQT----FQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSE--TRQSATSIKIMKEFGNFVKHGN 1658
+ L S +G V+G +K+ L+ I FL IPY PP G LRF +PQP SS++ + ++C M F G+ W P + E+ LY+N+W P L+ N PV++WIYGGG+ SGS++L +YD +L++ NIIVV+ NYR+ + GF+S+D E GN+G+ DQ+ ALQWI++NI F G+P N+T++G SAG SVSLHLL S F AI+ SG +W L++ E + R+ + A+NKI + + I +K+ II L +E + + GILQF + P VDG + D P+ L +++FK C + + +NE +YF+I N+ N ++ + F ++ F Y+P +P + + +Y N +I LD ++D F+ + A+ ++S VYY F + HWP W GV+H +EI Y FG S + S KIMK + NFVK GN
Sbjct: 42 YNNNRLIVSTKSGRVRGIRQKLPWLNETIDIFLGIPYANPPTGSLRFHRPQPISSWTNILSANKMPNSCYQN--MDNFFGDFEGSSMWNPNTKVSEDCLYLNIWTPYHTTLRRYRNLPVVIWIYGGGFYSGSTALNVYDSKILSTLNNIIVVTLNYRVNVFGFLSMDHEDAPGNVGMLDQLMALQWINDNIKVFGGDPNNITLMGESAGSVSVSLHLLSPLSQHLFNRAILQSGTANMNWATLSQQEAKQRTMELAINKIKCHKTNNLNNNTLSNIDTFDKMEIINCLIRTPAQELIDKMWITKGILQFPFVPVVDGYFLMDKPKNLVKKRQFKNCSILIGSNSNEASYFLIYELSNLLKLNTTSMNYRQFVESLKSLFNYHPKYPNEIKDYIFEAVKFQYTNWIDKNNKFANILNLDNAVSDAQFVCKVNDFADAYAQSGQNVYYYLFNHRSDNHHWPIWMGVLHGDEILYTFGEPFKMASNYTKKDRLFSRKIMKYWSNFVKTGN 546
BLAST of Carboxylic ester hydrolase vs. TrEMBL
Match: G3TFC3 (Carboxylic ester hydrolase OS=Loxodonta africana OX=9785 GN=BCHE PE=3 SV=1) HSP 1 Score: 276.559 bits (706), Expect = 7.196e-81 Identity = 189/561 (33.69%), Postives = 292/561 (52.05%), Query Frame = 3
Query: 141 FICNLICLDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVT---GILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNLSEVFRN------YDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
F+ + L + IK +T++ + + NG V+G VL + FL IPY +PP+G LRF+KPQ + +S I N K+ Q + F G + E W P E+ LY+NVW P+ + +N V+VWIYGGG+ +G+SSL++YDG LA E +IVVS NYR+ LGF++L + GN+G++DQ ALQW+ +NI+ F GNPK++T+ G SAG SVS HLL +S +F AI+ SG + W ++ E R+R+ L KF +REN+ IIK LQN + +E LL+ V +L + P VDG+ + D P L +FK + +EGT F++ P DN+ +I K F + + + FP + S ++ I Y P + LD ++ D I ++E S+ + ++ +FE + WP W GVMH EI ++FG L ++ ++ S IMK + NF K+GN + N + + Y+ +N + +S I++K + + RFW
Sbjct: 12 FLLWFLFLCVLIKKSYTEEDVIITTRNGRVRGMDLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWS-DIWNATKYANTCYQNTDQSFPG-FIGSEMWNPNTDLSEDCLYLNVWTPV---PKPKNATVMVWIYGGGFQTGTSSLQVYDGKFLARVERVIVVSMNYRVGALGFLALPGNHEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSITLFGESAGAASVSFHLLSPRSHPFFTRAILQSGSSNAPWAVMSVYEARNRT-----LTLAKF-------LGCSRENETEIIKCLQNKDPQEILLNEVFVVPYESLLSVNFGPTVDGDFLTDMPDTLLQLGQFKKTQIMVGVNKDEGTAFLVYGAPGFSKDNNSIITRKQFQEGLKIF--FPGV-SDFGKESILFHYTDWLDDQRPEHYREALDDVVGDYNIICPALEFTRKFSEMGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRINYTKAEEILSRSIMKRWANFAKYGNPNGTQSNGTRWPVFKSTEQKYLTLNTE--SSRIYTKLRAQQCRFW 550
BLAST of Carboxylic ester hydrolase vs. TrEMBL
Match: A0A2Y9RMN0 (Carboxylic ester hydrolase OS=Trichechus manatus latirostris OX=127582 GN=LOC101353513 PE=3 SV=1) HSP 1 Score: 273.863 bits (699), Expect = 6.532e-80 Identity = 189/561 (33.69%), Postives = 290/561 (51.69%), Query Frame = 3
Query: 141 FICNLICLDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVT---GILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNLSEVFRN------YDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
F+ + L + IK T++ + + NG V+G T VL + FL IPY +PP+G LRF+KPQ + S + N K+ Q + F G L E W P E+ LY+NVW P+ + +N V+VWIYGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++L + GN+G++DQ ALQW+ +NI+ F GNPK+VT+ G SAG SVSLHLL +S +F AI+ SG + W ++ E R+R+ L KF +REN+ IIK LQN + +E LL+ V +L + P VDG+ + D P L +FK + +EGT F++ P DN+ +I F + + + FP + S ++ I Y P + LD ++ D I ++E S+ + ++ +FE + WP W GVMH EI ++FG L ++ ++ S +MK + NF K+GN + N + + Y+ +N + +S +++K + + RFW
Sbjct: 12 FLLWFLFLCVLIKKSHTEEDIIITTRNGRVRGMTLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKRS-DVWNATKYANSCYQNIDQSFPG-FLGSEMWNPNTDLSEDCLYLNVWTPM---PKPKNATVMVWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNHEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPRSHPFFTRAILQSGSSNAPWAVMSIYEARNRT-----LTLAKF-------LGCSRENETEIIKCLQNKDPQEILLNEVFVVPYESLLSVNFGPTVDGDFLIDMPDTLLQLGQFKKTQIMVGVNKDEGTAFLVYGAPGFSKDNNSIITRTQFQEGLKIF--FPGV-SDFGKESILFHYTDWLDDQRPEHYREALDDVVGDYNIICPALEFTRRFSELGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTKAEEILSRSVMKRWANFAKYGNPNGTQSNGTRWPVFKSTEQKYLTLNTE--SSRVYTKLRAQQCRFW 550
BLAST of Carboxylic ester hydrolase vs. TrEMBL
Match: A0A3Q7VLY9 (Carboxylic ester hydrolase OS=Ursus arctos horribilis OX=116960 GN=BCHE PE=3 SV=1) HSP 1 Score: 271.937 bits (694), Expect = 9.634e-79 Identity = 194/552 (35.14%), Postives = 290/552 (52.54%), Query Frame = 3
Query: 177 KFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVT---GILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV--LNEPSLS--IDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNLS---------EVFRNYDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
K H + M+ + NG V+G + VL + FL IPY +PP+G LRF+KPQ + +S I N K+ Q + F G E W P E+ LY+NVW P + +N V+VWIYGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++L + + GN+G++DQ ALQW+ +NI+ F GNPK+VT+ G SAG SVSLHLL +S F AI+ SG + W ++ E R+R+ L KF +REN+ IIK L+N + +E LL+ LV +L + P VDG+ + D P L +FK + +EGT F++ P DN +I K F + + Y FP + S+ R+ I YV L++ D LD ++ D I ++E S+ + ++ +FE + WP W GVMH EI ++FG L +++ ++ S IMK + NF K+GN VF+N D+ Y+ +N + + +++K + + RFW
Sbjct: 66 KSHMEEDMV-ITTKNGKVRGVSLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQFLTKWS-DIWNATKYANSCYQNTDQSFPGFP-GSEMWNPNTDLSEDCLYLNVWVPT---PKPKNATVMVWIYGGGFQTGTSSLPVYDGKFLARVETVIVVSMNYRVGALGFLALPGNPEVPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAGSVSLHLLSPRSQPLFTRAILQSGSSNAPWAVMSLEEARNRT-----LTLAKFI-------GCSRENETEIIKCLRNKDPQEILLNEVLVVPSDTLLSVNFGPLVDGDFLTDMPDTLLQLGQFKKAQILVGVNKDEGTAFLVYGAPGFSKDNDSIITRKDFQEGLKMY--FPGV-SEFGRESILFYYVDLLDDQRAEKYRDALDDVLGDYNIICPALEFTKKFSELGNNAFFYYFEHRSSQLPWPEWMGVMHGYEIEFVFGLPLERRANYTKAEEILSRSIMKYWANFAKYGNPDGTQNNNTRWPVFKNTDQK---YLTLNTE--SPRVYTKLRAQQCRFW 591
BLAST of Carboxylic ester hydrolase vs. TrEMBL
Match: A0A452SR35 (Carboxylic ester hydrolase OS=Ursus americanus OX=9643 GN=BCHE PE=3 SV=1) HSP 1 Score: 270.781 bits (691), Expect = 9.920e-79 Identity = 193/552 (34.96%), Postives = 290/552 (52.54%), Query Frame = 3
Query: 177 KFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVT---GILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV--LNEPSLS--IDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETRQSAT--SIKIMKEFGNFVKHGNLS---------EVFRNYDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
K H + M+ + NG V+G + VL + FL IPY +PP+G LRF+KPQ + +S I N K+ Q + F G E W P E+ LY+NVW P + +N V+VW+YGGG+ +G+SSL +YDG LA E +IVVS NYR+ LGF++L + + GN+G++DQ ALQW+ +NI+ F GNPK+VT+ G SAG SVSLHLL +S F AI+ SG + W ++ E R+R+ L KF +REN+ IIK L+N + +E LL+ LV +L + P VDG+ + D P L +FK + +EGT F++ P DN +I K F + + Y FP + S+ R+ I YV L++ D LD ++ D I ++E S+ + ++ +FE + WP W GVMH EI ++FG L +++ ++ S IMK + NF K+GN VF+N D+ Y+ +N + + +++K + + RFW
Sbjct: 25 KSHMEEDMV-ITTKNGKVRGVSLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQFLTKWS-DIWNATKYANSCYQNTDQSFPGFP-GSEMWNPNTDLSEDCLYLNVWVPT---PKPKNATVMVWVYGGGFQTGTSSLPVYDGKFLARVETVIVVSMNYRVGALGFLALPGNPEVPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAGSVSLHLLSPRSQPLFTRAILQSGSSNAPWAVMSLEEARNRT-----LTLAKFI-------GCSRENETEIIKCLRNKDPQEILLNEVLVVPSDTLLSVNFGPLVDGDFLTDMPDTLLQLGQFKKAQILVGVNKDEGTAFLVYGAPGFSKDNDSIITRKDFQEGLKMY--FPGV-SEFGRESILFYYVDLLDDQRAEKYRDALDDVLGDYNIICPALEFTKKFSELGNNAFFYYFEHRSSQLPWPEWMGVMHGYEIEFVFGLPLERRANYTKAEEILSRSIMKYWANFAKYGNPDGTQNNNTRWPVFKNTDQK---YLTLNTE--SPRVYTKLRAQQCRFW 550
BLAST of Carboxylic ester hydrolase vs. Ensembl Cavefish
Match: ache (acetylcholinesterase (Cartwright blood group) [Source:NCBI gene;Acc:103043295]) HSP 1 Score: 217.624 bits (553), Expect = 2.258e-62 Identity = 161/506 (31.82%), Postives = 238/506 (47.04%), Query Frame = 3
Query: 186 FTKQMLNFSVSNGLVQGQTRKVLHRD-IAEFLSIPYCKPPIGELRFQKPQPFSSF-----SKSIINRGK--FDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEI-LNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELV---TGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQY-YPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQ--SETRQSATSIKIMKEFGNFVKHGN 1658
F+ L + G V G+ V R + FL IP+ +PP+G RF+ +P + +K N DT P P E W P E+ LY+NVW P N V+VWIYGGG+ SGSSSL++YDG LA E ++VVS NYR+ GF++ + GN+G+ DQ ALQW+ +NI F GNP+ VTI G SAGG SV +HLL +S F AI+ SGV W +T +E R R+ K + N +I L+N + E + V + + +F++ P VDG ++ D P + N FK + NEG+YF+I P DN +I + F + + PH I ++ + + + P + + +D I+ D I + A ++ S YL F+ WP W GV+H EI ++FG L ++ + S ++MK + NF + GN
Sbjct: 10 FSDAELTVTTRLGRVHGKRLPVPERGHVIAFLGIPFAEPPVGRRRFKPAEPKKPWNDVFEAKEYPNACYQFVDTSYPGFP---------GTEMWNPNRNMSEDCLYLNVWVPSS--PRPHNLTVMVWIYGGGFYSGSSSLDVYDGRYLAHSEKVVVVSMNYRVGAFGFLTFNGSSDAPGNVGLLDQRLALQWVQDNIQFFGGNPRQVTIFGESAGGASVGMHLLSPESRPKFTRAILQSGVPNCPWATVTFDEARRRATKLATLV------------GCPDGNDTELIACLRNRDPLELIEHEWQVLPYSSLFRFSFVPVVDGVVLPDSPEAMLNAGNFKDTQILLGVNQNEGSYFLIYGAPGFSKDNESLISREDFLEGVKMSVPHANEIGLEAVVLQYTDWMDEDNPLKNREAMDDIVGDHNVICPLQQFAKAYAQHGSIYLYL-FDHRASNLAWPEWMGVIHGYEIEFVFGLPLEKKLGYTVEEEKLSKRMMKYWANFARTGN 491
BLAST of Carboxylic ester hydrolase vs. Ensembl Cavefish
Match: ache (acetylcholinesterase (Cartwright blood group) [Source:NCBI gene;Acc:103043295]) HSP 1 Score: 208.379 bits (529), Expect = 9.848e-59 Identity = 161/527 (30.55%), Postives = 240/527 (45.54%), Query Frame = 3
Query: 201 LNFSVSNGLVQGQTRKVLHRD-IAEFLSIPYCKPPIGELRFQKPQPFSSF-----SKSIINRGK--FDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEI-LNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELV---TGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQY-YPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFI-------------------SGSIELANLI-------SKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQ--SETRQSATSIKIMKEFGNFVKHGN 1658
L + G V G+ V R + FL IP+ +PP+G RF+ +P + +K N DT P P E W P E+ LY+NVW P N V+VWIYGGG+ SGSSSL++YDG LA E ++VVS NYR+ GF++ + GN+G+ DQ ALQW+ +NI F GNP+ VTI G SAGG SV +HLL +S F AI+ SGV W +T +E R R+ K + N +I L+N + E + V + + +F++ P VDG ++ D P + N FK + NEG+YF+I P DN +I + F + + PH I ++ + + + P + + +D I+ D I +G++ NL S ++ +Y F+ WP W GV+H EI ++FG L ++ + S ++MK + NF + GN
Sbjct: 29 LTVTTRLGRVHGKRLPVPERGHVIAFLGIPFAEPPVGRRRFKPAEPKKPWNDVFEAKEYPNACYQFVDTSYPGFP---------GTEMWNPNRNMSEDCLYLNVWVPSS--PRPHNLTVMVWIYGGGFYSGSSSLDVYDGRYLAHSEKVVVVSMNYRVGAFGFLTFNGSSDAPGNVGLLDQRLALQWVQDNIQFFGGNPRQVTIFGESAGGASVGMHLLSPESRPKFTRAILQSGVPNCPWATVTFDEARRRATKLATLV------------GCPDGNDTELIACLRNRDPLELIEHEWQVLPYSSLFRFSFVPVVDGVVLPDSPEAMLNAGNFKDTQILLGVNQNEGSYFLIYGAPGFSKDNESLISREDFLEGVKMSVPHANEIGLEAVVLQYTDWMDEDNPLKNREAMDDIVGDHNVICPLQQFAKAYAQHGAQNAHAGAMNQGNLGYGNSAGNSGNSGSIYLYLFDHRASNLAWPEWMGVIHGYEIEFVFGLPLEKKLGYTVEEEKLSKRMMKYWANFARTGN 532
BLAST of Carboxylic ester hydrolase vs. Ensembl Cavefish
Match: ENSAMXT00000006974.2 (cholinesterase [Source:NCBI gene;Acc:103037776]) HSP 1 Score: 206.838 bits (525), Expect = 2.670e-58 Identity = 153/481 (31.81%), Postives = 235/481 (48.86%), Query Frame = 3
Query: 264 IAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQ--PVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELV---TGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTF-QYYPHFPIICSQSTRKKISVEYVLNEPSLS----IDILDRIIADQYFISGSIELAN-LISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYL--TQQSETRQSATSIKIMKEFGNFVKHGNLS 1664
+ FL IPY KPP+G LRF +P+P ++S + + +F Q F G E W P + E+ LY+NVW P L++ PV+VWIYGGG+ SG++SL++YDG L+ E ++VVS NYR+ LGF+SL E + GN ++DQ AL W+ ENI+ F G+P +VT+ G SAG S+ H+L S F AI+ SG + W + E +RS + + + P+ + ++ L+ I+ ++ + V T IL + P VDG+ + D P L +F + +EG YF+I + + +I F Q P F S+ R+ + +Y LS D L ++ D+YF ++ A + S YL F + WP W GVMH +EI ++FG L ++ + A S ++M+ + NF K GN S
Sbjct: 58 VVGFLGIPYAKPPLGALRFSRPEPVEAWS-GVRDTSQFSNSCWQSVDTKFQG-FAGAEMWNPNTKLSEDCLYLNVWTPSGRLQDPHQALVPVMVWIYGGGFSSGTASLDVYDGRYLSRSEEVVVVSMNYRLGPLGFLSLPGSEEVKGNAALFDQRLALTWVAENIAAFGGDPSSVTLFGESAGAGSIGHHVLSVGSHALFHRAILQSGSPNAVWAAVEATEAWNRSL----TLADLLNCPIG-------PSSNEVLTCLRTIDPEKIVNQQYTVIHDTTILNIPFPPTVDGDFLLDMPEVLMQSGQFLNTEILLGLNQDEGPYFLIYGAKGFGLSHQSLITRDQFLQGVASSLPGF----SEMAREAAAFQYTDWMDELSGQKNRDALGWLVGDRYFSCPLLDFARKYVEHGGSASLYL-FNHRSSSNAWPEWMGVMHGDEIEFVFGLPLNSSRGYTEEEVAMSRRMMRHWANFAKTGNPS 520
BLAST of Carboxylic ester hydrolase vs. Ensembl Cavefish
Match: nlgn4xb (neuroligin-4, X-linked-like [Source:NCBI gene;Acc:103022054]) HSP 1 Score: 202.601 bits (514), Expect = 1.490e-55 Identity = 154/492 (31.30%), Postives = 242/492 (49.19%), Query Frame = 3
Query: 150 NLICLDISIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDT-CPPQLPMRIFNGE--------NLDE-ETWIPKERQDENSLYVNVWCPLEILKEKEN--QPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNID--VDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG 1568
+L+ L + + F +T N+ G ++L + ++L +PY PP GE RFQ P+P +S+ I N +F CP L R+ + NLD T++ + Q+E+ LY+NV+ P E ++++ +PV+V+I+GG YV G+ ++ DGSVLAS N+IVV+ NYR+ +LGF+S D+ GN G+ DQ+ AL+W+ ENI F G+P+ VTI G+ AG VSL L S + FQ AI+ SG LS W AVN K+ + ++ + +++ LQN N+KE L++ + A+ P +DG++I DDP+ L + +F + I L V EG F+ S + D N F YP + R+ I Y P L + D +++ ++ A+L ++ S Y+ F Q E P W H +E+ Y+FG
Sbjct: 14 SLVMLHLFLNFQYTTVTTNYGKLRGFRALLPSEIL-APVEQYLGVPYALPPTGERRFQAPEPPNSW-PGIRNATQFAAVCPQYLEDRLLLSDMLPVWFTANLDTVATYV--QDQNEDCLYLNVYVPTEEDTQEDDGLKPVMVYIHGGSYVEGTGNM--IDGSVLASYGNVIVVTINYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWVKENIQAFNGDPRRVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSW--------------AVNYQPAKYTRMLAEKVGCNEDDSMEVVQCLQNKNYKE-LIEQNITPAKYHIAFGPVIDGDVIPDDPQILMEQGEF-LNYDIMLGVNQGEGYKFVDSIVDSEDGVTGNDFEFAISDFVDNLYGYPE----GKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPAWADSAHGDELPYVFG 479
BLAST of Carboxylic ester hydrolase vs. Ensembl Cavefish
Match: nlgn4xb (neuroligin-4, X-linked-like [Source:NCBI gene;Acc:103022054]) HSP 1 Score: 197.593 bits (501), Expect = 9.440e-54 Identity = 147/454 (32.38%), Postives = 227/454 (50.00%), Query Frame = 3
Query: 264 IAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDT-CPPQLPMRIFNGE--------NLDE-ETWIPKERQDENSLYVNVWCPLEILKEKEN--QPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNID--VDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG 1568
+ ++L +PY PP GE RFQ P+P +S+ I N +F CP L R+ + NLD T++ + Q+E+ LY+NV+ P E ++++ +PV+V+I+GG YV G+ ++ DGSVLAS N+IVV+ NYR+ +LGF+S D+ GN G+ DQ+ AL+W+ ENI F G+P+ VTI G+ AG VSL L S + FQ AI+ SG LS W AVN K+ + ++ + +++ LQN N+KE L++ + A+ P +DG++I DDP+ L + +F + I L V EG F+ S + D N F YP + R+ I Y P L + D +++ ++ A+L ++ S Y+ F Q E P W H +E+ Y+FG
Sbjct: 64 VEQYLGVPYALPPTGERRFQAPEPPNSW-PGIRNATQFAAVCPQYLEDRLLLSDMLPVWFTANLDTVATYV--QDQNEDCLYLNVYVPTEEDTQEDDGLKPVMVYIHGGSYVEGTGNM--IDGSVLASYGNVIVVTINYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWVKENIQAFNGDPRRVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSW--------------AVNYQPAKYTRMLAEKVGCNEDDSMEVVQCLQNKNYKE-LIEQNITPAKYHIAFGPVIDGDVIPDDPQILMEQGEF-LNYDIMLGVNQGEGYKFVDSIVDSEDGVTGNDFEFAISDFVDNLYGYPE----GKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPAWADSAHGDELPYVFG 492
BLAST of Carboxylic ester hydrolase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002735.1 (pep scaffold:Pmarinus_7.0:GL485913:3796:8263:-1 gene:ENSPMAG00000002501.1 transcript:ENSPMAT00000002735.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 122.479 bits (306), Expect = 7.906e-32 Identity = 73/229 (31.88%), Postives = 111/229 (48.47%), Query Frame = 3
Query: 264 IAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLP-------MRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKE--KENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLG-FISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEV 920
+ +FL +PY + P GE RF +P + +S + CP +P + ++ N TW+ +Q E L ++V+ P + E P+ V ++ G + +YDGS LA+ ++IVV YR+ +LG F S D + GN G+ DQV AL+W+ EN+ HF G+ VT+VG G SL L + FQ I SG LS W + E+
Sbjct: 1 VTQFLGVPYARAPRGERRFSAAEPPAVWSGEREAATRGPPCPQPVPNHRGWGMLPVWEAGNERLATWL-SSKQSEECLNLDVYIPGRDGESIPGERPPLAVMVFLHGGSFLDGAGGLYDGSALAAHGDVIVVIVTYRLGVLGSFFSTGDSLARGNYGLLDQVMALRWVRENVGHFGGDQGRVTLVGAGTGAACASLLALSHHAEGLFQRVIAQSGTALSSWALNHRPEL 228
BLAST of Carboxylic ester hydrolase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007813.1 (pep scaffold:Pmarinus_7.0:GL477731:150595:158527:1 gene:ENSPMAG00000007070.1 transcript:ENSPMAT00000007813.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 120.939 bits (302), Expect = 1.097e-30 Identity = 92/234 (39.32%), Postives = 130/234 (55.56%), Query Frame = 3
Query: 210 SVSNGLVQGQTRKVLHRDIA--EFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFL 905
+V+ G +QG R L + I+ F+ IPY KPPIG+LRF+KP P + + N F Q P L+E ++ + DE+ LY+NV+ P E+ + K V+VWI+GG Y G++ E Y+G LA+ +I+V+ NYR+ LG++S DE GN G+WDQ AL W+ NI F G+ VTI G S+GG LHL + S FQ A+ SG L+ W L
Sbjct: 45 TVARGKLQG-LRINLGQGISVEAFVGIPYAKPPIGDLRFRKPVPLEKWD-GVYNATTFSPACYQKPWF------LEEISFGKFDHFDEDCLYLNVFIP-EVSENK--MAVMVWIHGGAYRYGTA--EEYEGRFLAAA-GVILVTVNYRLGPLGWLSTGDEQSRGNYGLWDQHAALMWVKHNIESFGGDANRVTIFGESSGGGGTGLHLFSKHSQGLFQAAVSQSGCALAHWAIL 264
BLAST of Carboxylic ester hydrolase vs. Ensembl Sea Lamprey
Match: tg (thyroglobulin [Source:ZFIN;Acc:ZDB-GENE-030519-1]) HSP 1 Score: 101.293 bits (251), Expect = 2.351e-22 Identity = 76/231 (32.90%), Postives = 116/231 (50.22%), Query Frame = 3
Query: 213 VSNGLVQGQTRKV----LHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFS-KSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLS 890
+ +G +QG +R V + I FL +PY PP+ RF PQP + + ++ T P L G +L E+ LY+N++ P + N VLV+ +GG G S+ D S LA+ +IIVV+ NYR+ + GF+S DE GN G+ DQ AL+W+ ++ + F G+ VT+ G+ + +V LHL+ S FQ AI++ G LS
Sbjct: 2211 LGSGQLQGASRTVEVDSQVKVIDVFLGVPYAAPPLDANRFSGPQPPRPLAVNETWDADRYKTRPDCLQPDGQRGTSLSEDC-----------LYLNIFVPK---VKPHNASVLVFFHGGDNSFGGSAQGPLDPSYLAALGDIIVVTANYRLGLFGFLSTGDEAAAGNWGLLDQQAALRWVRDHAALFGGSAGAVTVAGDRSSADNVGLHLVAPGSRGLFQRAILMGGSVLS 2427
BLAST of Carboxylic ester hydrolase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007921.1 (pep scaffold:Pmarinus_7.0:GL476391:291925:322499:1 gene:ENSPMAG00000007162.1 transcript:ENSPMAT00000007921.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 57.7658 bits (138), Expect = 4.406e-9 Identity = 57/248 (22.98%), Postives = 95/248 (38.31%), Query Frame = 3
Query: 852 FQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDN-----KYFTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG 1568
FQ AI SG LS W A+N K+ + N + +++ L++ +F+E L++ ++ A+ P +DG++I DDP+ L + +F + EG F+ S +D+D+ N F YP R I Y N L + D +++ ++ A+L ++ S Y F Q E P W H +E Y+FG
Sbjct: 10 FQRAITQSGTALSSW--------------AINYQPVKYTRLLAENVNCNMLDTQDVVECLRSRSFRE-LVNQDIKPMRYHVAFGPVIDGDVIPDDPQILMEQGEFLNYDVMLGINQGEGLKFVESM---VDIDDGVSAANFDNIVSNFVDNLYGYPE----GKDELRATIKFMYTDWADRNNAETRRKTLVALFTDHQWVAPAMATADLHAQYGSPTYVYAFYHHCQSEMKPAWADAAHGDETPYVFG 235
BLAST of Carboxylic ester hydrolase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007815.1 (pep scaffold:Pmarinus_7.0:GL477731:150607:153327:1 gene:ENSPMAG00000007070.1 transcript:ENSPMAT00000007815.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 54.6842 bits (130), Expect = 4.877e-9 Identity = 51/146 (34.93%), Postives = 78/146 (53.42%), Query Frame = 3
Query: 210 SVSNGLVQGQTRKVLHRDIA--EFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILK-----EKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENII 626
+V+ G +QG R L + I+ F+ IPY KPPIG+LRF+KP P + + N F Q P L+E ++ + DE+ LY+NV+ P E+ + K+ V+VWI+GG Y G++ E Y+G LA+ I+
Sbjct: 41 TVARGKLQG-LRINLGQGISVEAFVGIPYAKPPIGDLRFRKPVPLEKWD-GVYNATTFSPACYQKPW------FLEEISFGKFDHFDEDCLYLNVFIP-EVSESMGQSHKDKMAVMVWIHGGAYRYGTA--EEYEGRFLAAAGVIL 175
BLAST of Carboxylic ester hydrolase vs. Ensembl Nematostella
Match: EDO37610 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFA0]) HSP 1 Score: 176.792 bits (447), Expect = 4.998e-48 Identity = 153/528 (28.98%), Postives = 252/528 (47.73%), Query Frame = 3
Query: 264 IAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKF-DTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILE-KFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTF---QYYPHFPIICSQSTRKKISVEYVLNEPSLSIDILD---------RIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYL--TQQS--ETRQSATSIKIMKEFGNFVKHGNLSEV------FRNYDESSNAYIKINEDLWTSAIFSKDQINKVRFW 1775
+ +FL +PY +PP+ LRF+ P P S++ SI +F D C R + G + ++R E+ LY+N++ P I + + PV+ +I+GGG+ +G+ ++ G L + I++V+ YR+ + GF++ D GN G+ DQV ALQW NI +F G P N+TI+G SAGG SV LHL+ S FQ AI +SGV S + L + V + KK V + LE FD + A+++ L+ + + LV P +DG + DDP RL + F P + V++EG++ + N V + M + F Q F ++Y S S K+S++ +L + + +D D +++D + I+ + L SK + Y F ++ P W GV+H + Y FG L QQ + + S ++ F NF K+GN + + ++ S+ AY+KI ++ + SK ++ FW
Sbjct: 49 VYKFLGVPYAEPPVKNLRFKGPIPPRSWAPSIYEATEFKDICTQSY--RHYGGSINNAWPTFTEKRFSEDCLYLNIYTP-SINPDGTHYPVIFYIHGGGFFAGTPIRDVTPGEFLPLR-GIVLVTVQYRLGIFGFLTTGDAEAPGNAGLLDQVEALQWTKRNIFNFGGEPNNITIMGESAGGASVGLHLMSPLSKGLFQRAIAVSGVEFSPFALLPNDVVVNYVKKTVAEELECNFD------------SSSAMLECLREMPSSKLEPYFNLVK--------PIIDGFFLPDDPHRLREQGDFHRVPLLSGFVSHEGSFLL----ENARV-KYTMEGMRNFAQHFLRMEFY-------SNSMPDKVSLDALLFQYTPWLDKKDSNKIRKKMIEMLSDSFVIAPTHASLTLHSKHGAPTYMFEFTHRSRRHKKPAWMGVVHGDTTAYKFGVPLLSAQQHIYDEQDRNVSDMLVTMFVNFAKYGNPTPSPVHGTNWERFNTSNKAYLKIQPNV---VLASKFHPARMAFW 537
BLAST of Carboxylic ester hydrolase vs. Ensembl Nematostella
Match: EDO47082 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN68]) HSP 1 Score: 176.022 bits (445), Expect = 6.526e-48 Identity = 152/548 (27.74%), Postives = 248/548 (45.26%), Query Frame = 3
Query: 222 GLVQGQTRKVLHR-DIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGE-NLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSD---WGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLT------------QQSETRQSATSIKIMKEFGNFVKHGNLSE------VFRNYDESSNAYIKINEDLWTSAIFSKDQINKVRFWEKLRRKF 1796
G V+G+ V+H + +F +IPY +PP+G+LRF P P +S + + + PQLP F LD E +E+ L ++V+ P +K+ + V+V+I+GGG+ SG+S YD SVL + ++IVV+ NYR+ +LGF ++ D GN G+ DQV ALQW+ +NI+ F GNPK+VTI G SAGG SVSLHLL S F I SG ++D ++ + + KAV FD + IT + + N+++ + L T P +D + D RRL E + + ANEG + I+ ++ P +C ++ + + N + + + +D FI+ +I AN ++ + + FE P +C +H +I Y FG LT ++ R+ S+ +MK + +F KHG+ + + Y+ ++ A++ I + F + KV FW + K
Sbjct: 16 GAVRGRLNPVVHGLQVRQFRAIPYAQPPVGKLRFAAPLPAKPWS-GVRDATQHGPVCPQLPDEEFGKMLGLDLPPGKTIENSNEDCLTISVYTPQNSDPDKQ-RAVMVFIHGGGFTSGAS--RDYDPSVLVALNDVIVVTINYRLGVLGFFNIPDTEYKGNYGLLDQVLALQWVQQNIASFGGNPKSVTIFGESAGGMSVSLHLLSPLSKGLFHRVIAQSGSAVTDSFVGHYVKTTALLEVFSKAVGC---PFDDKLVDCLRITSSEDVFAAQ--SNVSYPNNVGAQLLTT--------PVIDKHFLPDKARRLLGEGRVNKADVMLGVTANEGALLAMMTPGRIEGGLTLQELHQVIEYGLDTCPPDNTMCKEAIKFEYQDHRDPNNSVTNRQLYMDLYSDSMFIAPAIFEANALASAGHATFVYKFENLPDFFALPPYCASVHGIDIPYTFGFPLTLGESSPLFASLVRRHSEREKGLSMYMMKTWADFAKHGDPNHDGDAPVPWPRYNTTAQAHLVIAHEPRVEYKF---RAEKVAFWNEFIPKL 543
BLAST of Carboxylic ester hydrolase vs. Ensembl Nematostella
Match: EDO35390 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLM1]) HSP 1 Score: 151.369 bits (381), Expect = 3.122e-39 Identity = 135/467 (28.91%), Postives = 216/467 (46.25%), Query Frame = 3
Query: 156 ICLDISIKFHF-------TKQMLNFSVSNGLVQGQTRKVLHR-DIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEF-----LLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNIDVDN-----HKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVLNEPSLSIDILD---RIIADQYFISGSIELANLISKSNSKVYYLWF 1490
ICL + F F +Q + ++ G +QG V ++ FL IPY + P+GELRF PQP ++ I + + PQ P + N + L E I E+ L++NV+ P K PV+VWI+GGGY +++ +DGSVLAS N+IVV+ NYR+A+LGF+ + L GN G+ DQV AL+W+ +NI+ F GNP +VT+ G S+G SV+LH+L S FQ AI+ SG +S +G + R+ + +E+ +EN ++ L+ F++F +D + + P VD + D+P L +F ++ + +EGT+ S P HK + TQ C + I ++PS ++ + ++ D +F + AN ++K+ Y F
Sbjct: 5 ICLHLLSLFPFLFSVCSLAEQDVVITLEQGKIQGMREPVPGGYEVEIFLGIPYARAPVGELRFADPQPPLEWT-GIRDAKSYRAVCPQAPF-LPNFQPLTENDTI-----SEDCLFLNVYRPT---KFNHKLPVMVWIHGGGYYHATANW--FDGSVLASHNNVIVVTINYRLALLGFLHIPGTQLRGNYGMLDQVQALKWVQQNIASFGGNPSHVTLFGESSGAASVTLHILSPLSAGLFQTAIIESGSAVSPFGAYSP-----RASNHYDVFIERLGC-------FDKEN---LLNCLREKPFEDFERAVGGVDPRMPGPMFP---VPTVDKVFLPDEPEALLLAGRFNKIESVIIGFNKDEGTFLYSSAEPVTYAPPSIGAFHKAVHEVTLTQNGD-------DCELLKQAAIHRYTNHSDPSNPWNLWENWKNLMGDTFFFAPVTRTANSLAKAGISTYMYLF 434
BLAST of Carboxylic ester hydrolase vs. Ensembl Nematostella
Match: EDO31744 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX21]) HSP 1 Score: 146.747 bits (369), Expect = 2.451e-38 Identity = 126/443 (28.44%), Postives = 199/443 (44.92%), Query Frame = 3
Query: 291 CKPPIGELRFQKPQPFSSFSKSIINRGKFDT-CP-----PQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWN-EEITRENKI-AIIKFLQNINFKE--FLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYP----HFPIICSQSTRKKISVEYVLNEPSLSIDILD---RIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG 1568
+PP+ ELRF P+P + I N ++ CP P+ NGE+ ++ E+ LY+N++ P PV+VW++GGG GS Y SVL+S +IIVV+ N+R+A+ GF+ + L GN G DQV AL+W+H+NI +F G+P +VTI G SAGG SV H++ S F AI+ SG S++ F + + + I+ + P K N R K+ +K ++ +F++ FLL VDG+ + DDPR L +F +I + D K + N TF+ + H + KK + N + ++ + R+ D + + S+ A+ S + Y F + ++P W GV H +E+ YLFG
Sbjct: 1 AEPPVDELRFASPKP-PKYWNGIRNATEYSAVCPQPTHSPRFQPLYENGESSIVDSHC--SHISEDCLYLNIYRPAH---SHHRLPVMVWLHGGGNYVGSG--NWYHSSVLSSHNDIIVVTLNHRLALFGFLYISGTDLAGNYGYLDQVQALKWVHQNIGNFGGDPNSVTIFGESAGGASVHFHIMSPMSAGLFHKAIIQSGNANSNFAFHSPD------SSDYDWIINELGCPDKKNLLRCLRTKKVEEFMKLMRPFSFRKLGFLLPVT------------SVDGQFVPDDPRNLQQTHQFNNLTSIMIGFTK---------------DEAKFLSNDLNPMTFELFEKIVQHLHLYGDCEIVKKAVLHRYKNHTNPQENMYENIARLFGDMAYFAPSVLTADSFSSAGIPTYMYQFSHRSSFSNFPEWLGVPHFDELQYLFG 402
BLAST of Carboxylic ester hydrolase vs. Ensembl Nematostella
Match: EDO46238 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQW3]) HSP 1 Score: 146.747 bits (369), Expect = 6.335e-38 Identity = 138/510 (27.06%), Postives = 228/510 (44.71%), Query Frame = 3
Query: 195 QMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETW--IPKERQDENSLYVNVWCPL-----EILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYP------HFPIICSQSTRKKISVEYV------LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFG---HYLTQQSETRQSA-TSIKIMKEFGNFVKHG 1655
++L + + QG RK I +FL IPY + PIG+LRF+ PQP + + I N F Q + ++ TW K+ E+ L +N++ P + ++ ++ PVL +I+GG Y G+ + G + A + I++V+ +YR+ +LGF++ D GN G+ DQ+ AL+W+ ENI+ F G+P +T+VGNSAG SV LHLL + FQ AIM SG LS + +SK +L E+ + ++K LQ D E + AP VD + D PR L E KF+ P + ++G + I D++ + YF + + H P+ + R ++E+ +P L + D + ++ ++E AN S+ ++ YL+ + W HS Y FG H T + T++ S +++ + NF+K G
Sbjct: 39 KVLGLAQTLASAQGPARK-----INKFLGIPYAQQPIGDLRFKPPQPLKPWKEKIYNATSFGNICVQSKLYFEFLKSSIRRTWPDFSKKNMREDCLNLNIYTPAWPDISDSVQTRKAYPVLFYIHGGSYYLGTPNRVKTPGEI-APQYGIVLVTIHYRLGVLGFLTTGDVEAPGNAGMLDQIQALRWVKENIAGFGGDPNQITLVGNSAGASSVGLHLLSPLTKGLFQKAIMESGTELSPFAVNPLKTAIAKSKNVAKNLL------------CDTEDHVRMVKCLQT-------KDAEDLAFYYDPFPAPHVDNYFLLDTPRSLRKEGKFQPLPLMLGFTKHDGFHMI------SDLELPDQLTPSYFRKGIERALQKFMKIHDPMT---AVRLADAIEFTYQPWAKTTDPDELYKALVALCTDIFIVAPTMESANFHSEYSAT--YLFEYSHISNNSRLKWA--THSSNADYTFGAPIHNATHIAYTKEDRNVSHLLLQLYSNFLKFG 510
BLAST of Carboxylic ester hydrolase vs. Ensembl Medaka
Match: bche (butyrylcholinesterase [Source:NCBI gene;Acc:100529181]) HSP 1 Score: 223.787 bits (569), Expect = 1.253e-64 Identity = 153/501 (30.54%), Postives = 255/501 (50.90%), Query Frame = 3
Query: 189 TKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPL-EILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDT-ELVTG--ILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISV----EYVLNEPSL-SIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYL-TQQSETRQSAT-SIKIMKEFGNFVKHG 1655
T+ L + ++G VQG+ VL ++ FL IPY KPP+G+LRF+ P+P + +++ + KF Q+P F G E W P E+ LY+NVW P+ + + PVLVWI+GGG+V+G+S++++Y G +L+ E ++VVS NYR+ GF+SL D++ + GN G+ DQ AL+W+ NI+ F G+P VT+ G SAG SV HLL S +FQ A+M SG + W + + ++ DRS + + PM N+ + LQ + K+ +++T +L F + P VDG + + +L + +EGT F++ P + +I + F + + + S K+ + ++ E + + D + +++ DQ F+ ++ AN S++ K ++ +F+ + WP W GV H EI ++FG L T T+ + KIMK + NF + G
Sbjct: 26 TRDDLVINTTHGKVQGKLISVLGGEVRAFLGIPYGKPPLGKLRFRAPEPAEKW-EAVKDATKFPNSCYQMPDTAFPGFQ-GAEMWNPNTPLSEDCLYLNVWTPVFNKTQPLPSAPVLVWIHGGGFVTGTSTIDLYHGHILSKSEGVVVVSINYRLGAFGFLSLPDNKNIRGNAGLLDQSLALRWVSSNIAAFGGDPSKVTLFGESAGAASVGFHLLSPASHGFFQRAVMQSGCPNAPWATVNQKDLWDRSM----MLSKALGCPM--------SNRGLLETCLQQADAKKITAKQYDIITKPPLLNFPFGPTVDGVFLTAEVEKLLTGGNLPKKELMIGLNKDEGTCFLVYGSPGFSITGQSLISRRDFLAGV----NLTLTNAHSIIKEAVIFEYTDWTDKESRMKNRDSIGQLVGDQMFVCPVVDFANKYSQNGGKTFFYFFDHRSSLMSWPEWMGVAHGYEIEFVFGMPLNTSLGYTKNEVNMTKKIMKHWTNFARTG 508
BLAST of Carboxylic ester hydrolase vs. Ensembl Medaka
Match: bche (butyrylcholinesterase [Source:NCBI gene;Acc:100529181]) HSP 1 Score: 223.787 bits (569), Expect = 1.253e-64 Identity = 153/501 (30.54%), Postives = 255/501 (50.90%), Query Frame = 3
Query: 189 TKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPL-EILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDT-ELVTG--ILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISV----EYVLNEPSL-SIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYL-TQQSETRQSAT-SIKIMKEFGNFVKHG 1655
T+ L + ++G VQG+ VL ++ FL IPY KPP+G+LRF+ P+P + +++ + KF Q+P F G E W P E+ LY+NVW P+ + + PVLVWI+GGG+V+G+S++++Y G +L+ E ++VVS NYR+ GF+SL D++ + GN G+ DQ AL+W+ NI+ F G+P VT+ G SAG SV HLL S +FQ A+M SG + W + + ++ DRS + + PM N+ + LQ + K+ +++T +L F + P VDG + + +L + +EGT F++ P + +I + F + + + S K+ + ++ E + + D + +++ DQ F+ ++ AN S++ K ++ +F+ + WP W GV H EI ++FG L T T+ + KIMK + NF + G
Sbjct: 26 TRDDLVINTTHGKVQGKLISVLGGEVRAFLGIPYGKPPLGKLRFRAPEPAEKW-EAVKDATKFPNSCYQMPDTAFPGFQ-GAEMWNPNTPLSEDCLYLNVWTPVFNKTQPLPSAPVLVWIHGGGFVTGTSTIDLYHGHILSKSEGVVVVSINYRLGAFGFLSLPDNKNIRGNAGLLDQSLALRWVSSNIAAFGGDPSKVTLFGESAGAASVGFHLLSPASHGFFQRAVMQSGCPNAPWATVNQKDLWDRSM----MLSKALGCPM--------SNRGLLETCLQQADAKKITAKQYDIITKPPLLNFPFGPTVDGVFLTAEVEKLLTGGNLPKKELMIGLNKDEGTCFLVYGSPGFSITGQSLISRRDFLAGV----NLTLTNAHSIIKEAVIFEYTDWTDKESRMKNRDSIGQLVGDQMFVCPVVDFANKYSQNGGKTFFYFFDHRSSLMSWPEWMGVAHGYEIEFVFGMPLNTSLGYTKNEVNMTKKIMKHWTNFARTG 508
BLAST of Carboxylic ester hydrolase vs. Ensembl Medaka
Match: bche (butyrylcholinesterase [Source:NCBI gene;Acc:100529181]) HSP 1 Score: 223.787 bits (569), Expect = 1.253e-64 Identity = 153/501 (30.54%), Postives = 255/501 (50.90%), Query Frame = 3
Query: 189 TKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPL-EILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISL-DDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDT-ELVTG--ILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISV----EYVLNEPSL-SIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYL-TQQSETRQSAT-SIKIMKEFGNFVKHG 1655
T+ L + ++G VQG+ VL ++ FL IPY KPP+G+LRF+ P+P + +++ + KF Q+P F G E W P E+ LY+NVW P+ + + PVLVWI+GGG+V+G+S++++Y G +L+ E ++VVS NYR+ GF+SL D++ + GN G+ DQ AL+W+ NI+ F G+P VT+ G SAG SV HLL S +FQ A+M SG + W + + ++ DRS + + PM N+ + LQ + K+ +++T +L F + P VDG + + +L + +EGT F++ P + +I + F + + + S K+ + ++ E + + D + +++ DQ F+ ++ AN S++ K ++ +F+ + WP W GV H EI ++FG L T T+ + KIMK + NF + G
Sbjct: 26 TRDDLVINTTHGKVQGKLISVLGGEVRAFLGIPYGKPPLGKLRFRAPEPAEKW-EAVKDATKFPNSCYQMPDTAFPGFQ-GAEMWNPNTPLSEDCLYLNVWTPVFNKTQPLPSAPVLVWIHGGGFVTGTSTIDLYHGHILSKSEGVVVVSINYRLGAFGFLSLPDNKNIRGNAGLLDQSLALRWVSSNIAAFGGDPSKVTLFGESAGAASVGFHLLSPASHGFFQRAVMQSGCPNAPWATVNQKDLWDRSM----MLSKALGCPM--------SNRGLLETCLQQADAKKITAKQYDIITKPPLLNFPFGPTVDGVFLTAEVEKLLTGGNLPKKELMIGLNKDEGTCFLVYGSPGFSITGQSLISRRDFLAGV----NLTLTNAHSIIKEAVIFEYTDWTDKESRMKNRDSIGQLVGDQMFVCPVVDFANKYSQNGGKTFFYFFDHRSSLMSWPEWMGVAHGYEIEFVFGMPLNTSLGYTKNEVNMTKKIMKHWTNFARTG 508
BLAST of Carboxylic ester hydrolase vs. Ensembl Medaka
Match: ache (acetylcholinesterase (Cartwright blood group) [Source:NCBI gene;Acc:101161586]) HSP 1 Score: 218.394 bits (555), Expect = 1.668e-62 Identity = 159/496 (32.06%), Postives = 235/496 (47.38%), Query Frame = 3
Query: 258 RDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEI-LNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELV----TGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVANEGTYFIISRFPNIDVDNHKMIDNKYFTQTFQY-YPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELA------------------NLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQ--SETRQSATSIKIMKEFGNFVKHGNLSE 1667
R + FL IP+ +PP+G+ RF+ +P + + + + Q + + G E W P E+ LY+N+W P + + N PV+VWIYGGG+ SGSSSL++YDG LAS EN+IVVS NYRI GF++LD GN+G+ DQ ALQW+ NI+ F G+P+ VTI G SAGG SV HLL S F AI+ SGV W +T E R R+ + N + N ++ L+ +E L+D E T + +F++ P VDGE++ D P + N FK + +EG+YF++ P DN +I K F + PH I ++ + + N + D +D I+ D I A N S VY F+ WP W GV+H EI ++FG L ++ + + S ++M+ + NF + GN +E
Sbjct: 49 RPVVGFLGIPFGEPPVGKRRFRPAEPKRPW-QGVYKADSYPNACFQFVDKSYPGFP-GIEMWNPNREMSEDCLYLNIWVPSSV--KPHNLPVMVWIYGGGFYSGSSSLDVYDGRYLASVENVIVVSMNYRIGAFGFLALDGTSEAPGNVGLLDQRMALQWVQNNIASFGGDPRQVTIFGESAGGASVGYHLLSPGSRPLFTRAILQSGVPNCPWASVTYAEARRRATQLANAV------------GCNGGNDTELVDCLRGKTPQE-LIDQEWQVLPWTALFRFSFVPVVDGEVLPDAPEAMVNSGDFKDTQILLGVNQDEGSYFLLYGAPGFSKDNDSLISRKDFLAGVKMGVPHANDIGLEAVVLQYTDWMDENNGEKNRDAMDDIVGDHNVICPLALFASSYARHHAEKANNGFGHLNNAGNSQGGVYLYLFDHRASNLAWPEWMGVIHGYEIEFVFGLPLEKRLNYTSEEEKLSRRMMRYWANFARTGNPNE 527
BLAST of Carboxylic ester hydrolase vs. Ensembl Medaka
Match: nlgn3b (neuroligin 3b [Source:NCBI gene;Acc:100529175]) HSP 1 Score: 181.415 bits (459), Expect = 3.456e-48 Identity = 147/491 (29.94%), Postives = 236/491 (48.07%), Query Frame = 3
Query: 258 RDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKF-DTCP-------PQLPMRIFNGENLDE-ETWIPKERQDENSLYVNVWCPLEI-LKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNIDVDNHKMIDNKY--FTQTFQYYPHFPIICSQSTRKKISVEYV----LNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSE------TRQS-ATSIKIMKEFGNFVKHGN 1658
R + ++L +PY PP+GE RF P+ SS+S + N F CP P++ M I+ NLD T+I + Q E+ LY+N++ P + +++ E +PV+V+I+GG Y+ G+ ++ DGS+LAS N+IVV+ NYRI +LGF+S D+ GN G+ DQ+ AL+WI +NI +F G+P +T+ G+ G VSL L S F AI+ SG LS W AVN K+ + + + ++ LQ + KE L++ ++ + A+ P +DG++I DDP L + +F + I L V EG F+ + D + D F + YP + R+ I Y + P L + D ++ S+ A+L ++ S Y+ F Q P W H +E+ Y+FG + ++ +R S +M + NF K G+
Sbjct: 72 RPVDQYLGVPYAAPPVGEKRFMPPEQPSSWS-GVKNATHFMPVCPQNIHSTVPEIMMPIWFTYNLDTVATYI--QDQSEDCLYLNIYAPTDDDIRDSEARPVMVYIHGGSYMEGTGNM--MDGSILASYGNVIVVTLNYRIGILGFLSTGDQAAKGNYGLLDQIQALRWISKNIGYFGGDPGRITVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSALSSW--------------AVNYQPVKYTRMLAERVGCNVLDTVDMVSCLQKKSAKE-LVEQDIQAARYRVAFGPVIDGDVIPDDPEILMEQGEF-LNYDIMLGVNQGEGLRFVENAMDLEDGVSGSDFDFAVSDFVDSLYGYPE----GKDTLRETIKFMYTDWADKDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPVWSDSAHGDEVPYVFGIPMVGPTDLFPCNFSRNDIMLSAVVMTYWTNFAKSGD 537
BLAST of Carboxylic ester hydrolase vs. Planmine SMEST
Match: SMESG000005630.1 (SMESG000005630.1) HSP 1 Score: 201.06 bits (510), Expect = 4.269e-56 Identity = 166/586 (28.33%), Postives = 268/586 (45.73%), Query Frame = 3
Query: 222 GLVQGQTRKVLHRDIAE-----FLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFD-TCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKE--KENQ------PVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNVA---NEGTYFIISRF-PNIDVDNHK----MIDNKYFTQTFQYYPHFPIICSQSTRKKISVEY----VLNEPSLSIDILDRIIADQYFISGSIELANLISKSNS------------KVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSET-------RQSATSIKIMKEFGNFVKHGNLS--------------------EVFRNYDESSNAYIKINEDL-WTSAIFSKDQINKVRFWEK 1781
G + G KV D + + IPY PP+ LRF+KP PF S+ ++N +C N W+ DE+ LY+N+W P + K NQ V+VWIYGG + SG++ LE+Y+G LA+++N+IVVS NYR+ GFI L + ++ GN+G+WDQ AL+W+ ENI F G+ +TI G SAG SVS H++ S F+NAIM SG L WG +++N +R+K +N++ + K E R+ + Q + +L D + P +D + + F + + PT L + NEG+YF++ F PN D N+K + +NK + + + + EY + + P ++ L+ I +D+ F +IE+A +++ N Y+ F T+ WP W G +H EI Y+FG ++ E + S +M+ + NF +HG+ + V+ +D ++ +YI I ED T+++ K + K FW +
Sbjct: 33 GTINGFISKVEWNDRSATTVHIYYGIPYAIPPVKNLRFKKPVPFPEISEKVVNAQTHKPSCHQYNDTSYLN--TAGARMWVSPIPFDEDCLYLNIWVPQNPAPDVHKMNQKTTDKLAVMVWIYGGSFASGAAGLEVYEGRYLAARQNVIVVSMNYRLGPFGFIYLKNGLIPGNMGLWDQRLALKWVKENIEFFGGDSDKITIFGESAGSVSVSAHVISPWSQNLFRNAIMQSGSVLGYWGLISRNTSEERTKILMNRLKCRGSLHAK--VECLRQ-----LPAKQLTDAHSYLYD---ANSYFSVPFPPVIDNHFLPYPNSQAF-KNLVHVKPTGALMLGMNKNEGSYFMLYSFIPNSDWLNNKTSVQIANNKDYQEKLRKVLDLEAKIPSQILSLVDFEYTDYNLPDTPQNRVNRLEEISSDRSFKCPTIEMAKMVNNDNRFEKGLGKRSVTLPTYFYEFRYRTKSLPWPEWMGTIHGLEIDYVFGVPFNKKFEKIFYEFTDEERRISDVVMQYWANFARHGDPNIMPNDKLVSDYDVSINGKPLRVWPEFDNTTQSYIIIKEDGNLTTSVNPKKR--KCLFWRR 603
BLAST of Carboxylic ester hydrolase vs. Planmine SMEST
Match: SMESG000010788.1 (SMESG000010788.1) HSP 1 Score: 194.512 bits (493), Expect = 1.077e-53 Identity = 166/578 (28.72%), Postives = 263/578 (45.50%), Query Frame = 3
Query: 234 GQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFS-KSIINRGKFDTCPPQLPMRIFNGE----NLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRS---KKAVN------------KILEKFDFPMKWNEEITRENKIAIIK--FLQNINFKEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFI-------ISRFPNIDVDNHKMID---------NKYFTQTF-----QYYPHFPIICSQSTRKKISVEYVLNEPSLSIDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSE-------TRQSATSIKIMKEFGNFVKHGNLSEVFRNYDESSNAYIKINEDLWTSAIFS---KDQINKVRFWEK-LRRKFYD 1802
G T + + I F IPY PPI LRF+ PQ K + N T P ++ GE N W+ K E+ LY+ +W P + K PV+VWIYGG + SGSS+LE+YDGS+LA+K ++VVS YR+ LGF+ LDD + GN G+ DQ AL+W+ +NI +F G+ +++TI G SAG VS+H+L S F+ AIM S + W TK E +++ K VN K L+K + +++ +N + + L+ K D I + P D I L N+ FK + + ANEG +F+ ++ F +V++ ++ +K+ + Y P++ + + + + LD++ DQ F+ I+ A L++ N KVY F+ T +P W G MH EI Y+FG ++ + T ++ S IM + NF K GN + Y +S+ ++ N S F+ + Q+N R +K ++ KF++
Sbjct: 44 GLTLNIYGKTIDHFARIPYALPPINNLRFKYPQEIVGNQWKGVYNA----TTSPNTCWQVEGGEFDKLNPAARLWLSKTPMSEDCLYLTIWSPRTV---KTKLPVMVWIYGGSFFSGSSTLEVYDGSILAAKHEVVVVSLQYRLGPLGFLYLDDTLAPGNQGLMDQRMALKWVKDNIYNFNGDSESITIFGESAGSVGVSIHVLSPLSNNLFKRAIMESATASAAWAIETKKESKEKGLAISKFVNCNYDSWQVNVLLKCLQKVKPDLLVSKQFDLKNIVNKQRSDLLRRRGVKNLFTDASFFFDIF---FRPTYDANFINQPVNLLLNDSTFKPNIELLMGYNANEGMFFLLYGLNKWLNFFNKGEVEDTSLLSSNNPNYIKASKFLLENLTPNDIAYTNLLPLLLHEYKIPSTIFNWKKWNSTDVLSALDQLTGDQNFVCPVIDYAELLADKNVKVYLYSFQHRTSRMTFPKWTGTMHGYEIEYVFGMPFSKNFQNLFYTFTTEEAKLSNYIMTLWANFAKFGNPTTQKIEYFDSTLSWPLYNTTSKLSVYFTTPHESQLNAARLNDKAMKCKFWN 611
BLAST of Carboxylic ester hydrolase vs. Planmine SMEST
Match: SMESG000017894.1 (SMESG000017894.1) HSP 1 Score: 180.644 bits (457), Expect = 9.168e-49 Identity = 161/539 (29.87%), Postives = 248/539 (46.01%), Query Frame = 3
Query: 228 VQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQ-----PFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCPLEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIAIIKFLQNINF-------------------KEFLLDTELVTGILQFAWAPCVDGELIKDDPRRLFNEKKFKICPTIFLNV-ANEGTYFIISRFPNIDVDNHKMID-NKYFTQTFQYYPHFPIICSQSTRKKISVEYVLN----EPSLS------------------------IDILDRIIADQYFISGSIELANLISKS-NSKVYYLWFETFTQPEHWPNWCGVMHSEEIYYLFGHYLTQQSETR-------QSATSIKIMKEFGNFVKHGN 1658
++G++ + + I F IPY KPPIG RF+ P+ P++ S + TC P F +N + W K E+ LY+ +W P +I E PV++WIYGG Y+SGSS+LE+YDGS+LAS N+++VSF +R LGF+ LDD GN I DQ L+W++ +I F G+PK VT+ G S+G S+S+HL + S +YFQ AI+ SG W E S + EK + + N+EI + + + L N+NF K+F D L I + P D ++I +E + + + ANE +F++ + N K+ + +K + YP + + KI +E +L+ PSL+ + LD I D FI +I+ A+ ++KS +SK++ F T P+W GVMH EI Y+FG + + + S +MK + NF K+GN
Sbjct: 35 LKGKSIFKMGKKIFHFSKIPYAKPPIGNRRFRYPEKLNNPPWTGVYDSTVQPL---TCWQGAPSIEFELKNPIGKMWFSKTVMSEDCLYLTIWTP-QINAANELLPVMIWIYGGSYMSGSSTLEVYDGSILASLHNVVIVSFQFRSGPLGFLYLDDTESPGNQAIMDQHMLLKWVNNHIVSFGGDPKKVTLFGESSGATSISVHLFSKISEKYFQRAILQSGTIFVPWAI----ESSSASYIKAKYLAEKANCTSRNNQEIVKCLRSTKPEVLVNLNFLIRDQIAKTRKEKLMKEGYKDFYSDAALFFDIY---FRPIFDQKIISKLDVEKISEGQLVTNKDLLIGTNANEAMFFLMYGLSS----NFKLFESSKIVLPSKMSYPS----ENYTDPYKIVLENILDLDYLYPSLTKLILHEYGIQSQHFDDKSWTSKEILQKLDFIGGDMQFICPTIQFADSVTKSKSSKLFMYLFNCRTNGTEVPDWLGVMHGYEIEYVFGMPFSSDFTSNLYSFNDDEKNVSRSVMKFWTNFAKYGN 554
BLAST of Carboxylic ester hydrolase vs. Planmine SMEST
Match: SMESG000005922.1 (SMESG000005922.1) HSP 1 Score: 160.614 bits (405), Expect = 8.363e-42 Identity = 149/520 (28.65%), Postives = 231/520 (44.42%), Query Frame = 3
Query: 171 SIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCP-------LEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIA-IIKFLQNINFKEFLLDT----------ELVTGILQFA-------WAPCVDGELIKDDPRRLFNEKKFKIC--PTIFLNVANEGTYFIISRF--------------------PNI----DVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVLNEPSLS---------IDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEE 1550
+ F+ + + S +NG + G + VL + + FL IPY KPP+G LRF+ P+ + + + TC LP + N W E+ LY+++W P ++ EK LVWI+GGG+ GSS+L+IY+G +LASK N+IVV+ YR+ GF+S + + + GN G+ DQV ALQWI +NI F G+ K VTI G ++G S S HLL + + F AIM SG LS W + D K A++K + N + T E K + + + L++++ +++ +L IL +A + P + G + P F K+ KI + NEG + F PN D+ H ++++K+ HF I + I+ EY L I++ D I D F ++ A+ K ++VY FE TQ P W GV+ +E
Sbjct: 17 GLTFNRNGEYVTVSTTNGNIMGIKKDVLGKPVYVFLGIPYAKPPVGRLRFRNPELVNKWEGTYSATKLPKTCYQNLPEH-YELNNPAWRIWTNNTEMSEDCLYLSIWTPKINKNQNRKMFNEKFIISTLVWIHGGGFTGGSSTLDIYNGEILASKMNVIVVNIQYRLGPFGFLSYNVKEIPGNQGLMDQVLALQWIRDNIGFFGGDSKLVTIFGANSGAVSASFHLLSPLTQDLFNQAIMQSGSALSWWAY-------DDPKTAISKAYHFANLSGCHNSKETVEIKTSDLFECLRSLDPITLVVNQWKMLNERYREKLTKPILPYASFYFDIPFKPTIGGLYLPKPPSSYFAGKEPKILRKRVMLGTTKNEGLIHLFKGFRHYFMPSDDSLVQPALFRYGPNTKDPADLLAHYIVNDKFVN-------HFNI-------EAIAFEYELPSKIFQQSNWKSQDIINVFDNIAGDFSFKCPVVDFADKYLKI-AQVYLYSFEQQTQFLPLPPWSGVLQGQE 513
BLAST of Carboxylic ester hydrolase vs. Planmine SMEST
Match: SMESG000005922.1 (SMESG000005922.1) HSP 1 Score: 160.229 bits (404), Expect = 9.520e-42 Identity = 149/520 (28.65%), Postives = 231/520 (44.42%), Query Frame = 3
Query: 171 SIKFHFTKQMLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFSKSIINRGKFDTCPPQLPMRIFNGENLDEETWIPKERQDENSLYVNVWCP-------LEILKEKENQPVLVWIXXXXXXXXXXXLEIYDGSVLASKENIIVVSFNYRIAMLGFISLDDEILNGNLGIWDQVCALQWIHENISHFKGNPKNVTIVGNSAGGCSVSLHLLIEKSWEYFQNAIMLSGVCLSDWGFLTKNEVRDRSKKAVNKILEKFDFPMKWNEEITRENKIA-IIKFLQNINFKEFLLDT----------ELVTGILQFA-------WAPCVDGELIKDDPRRLFNEKKFKIC--PTIFLNVANEGTYFIISRF--------------------PNI----DVDNHKMIDNKYFTQTFQYYPHFPIICSQSTRKKISVEYVLNEPSLS---------IDILDRIIADQYFISGSIELANLISKSNSKVYYLWFETFTQPEHWPNWCGVMHSEE 1550
+ F+ + + S +NG + G + VL + + FL IPY KPP+G LRF+ P+ + + + TC LP + N W E+ LY+++W P ++ EK LVWI+GGG+ GSS+L+IY+G +LASK N+IVV+ YR+ GF+S + + + GN G+ DQV ALQWI +NI F G+ K VTI G ++G S S HLL + + F AIM SG LS W + D K A++K + N + T E K + + + L++++ +++ +L IL +A + P + G + P F K+ KI + NEG + F PN D+ H ++++K+ HF I + I+ EY L I++ D I D F ++ A+ K ++VY FE TQ P W GV+ +E
Sbjct: 17 GLTFNRNGEYVTVSTTNGNIMGIKKDVLGKPVYVFLGIPYAKPPVGRLRFRNPELVNKWEGTYSATKLPKTCYQNLPEH-YELNNPAWRIWTNNTEMSEDCLYLSIWTPKINKNQNRKMFNEKFIISTLVWIHGGGFTGGSSTLDIYNGEILASKMNVIVVNIQYRLGPFGFLSYNVKEIPGNQGLMDQVLALQWIRDNIGFFGGDSKLVTIFGANSGAVSASFHLLSPLTQDLFNQAIMQSGSALSWWAY-------DDPKTAISKAYHFANLSGCHNSKETVEIKTSDLFECLRSLDPITLVVNQWKMLNERYREKLTKPILPYASFYFDIPFKPTIGGLYLPKPPSSYFAGKEPKILRKRVMLGTTKNEGLIHLFKGFRHYFMPSDDSLVQPALFRYGPNTKDPADLLAHYIVNDKFVN-------HFNI-------EAIAFEYELPSKIFQQSNWKSQDIINVFDNIAGDFSFKCPVVDFADKYLKI-AQVYLYSFEQQTQFLPLPPWSGVLQGQE 513 The following BLAST results are available for this feature:
BLAST of Carboxylic ester hydrolase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Carboxylic ester hydrolase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Carboxylic ester hydrolase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30023427 ID=SMED30023427|Name=Carboxylic ester hydrolase|organism=Schmidtea mediterranea sexual|type=transcript|length=1849bpback to top protein sequence of SMED30023427-orf-1 >SMED30023427-orf-1 ID=SMED30023427-orf-1|Name=SMED30023427-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=538bp MLNFSVSNGLVQGQTRKVLHRDIAEFLSIPYCKPPIGELRFQKPQPFSSFback to top Annotated Terms
The following terms have been associated with this transcript:
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