Multidrug and toxin extrusion protein

Overview
NameMultidrug and toxin extrusion protein
Smed IDSMED30023424
Length (bp)2504
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Multidrug and toxin extrusion protein (SMED30023424) t-SNE clustered cells

Violin plots show distribution of expression levels for Multidrug and toxin extrusion protein (SMED30023424) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Multidrug and toxin extrusion protein (SMED30023424) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Multidrug and toxin extrusion protein (SMED30023424) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023424

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30023424SMESG000005478.1 SmedASXL_016390SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30023424SMESG000005478.1 SmedASXL_016390SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30023424SMESG000005478.1 dd_Smed_v4_12128_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30023424SMESG000005478.1 dd_Smed_v4_12128_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30023424SMESG000005478.1 dd_Smed_v4_12128_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30023424SMESG000005478.1 dd_Smed_v6_12128_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30023424SMESG000005478.1 OX_Smed_1.0.06744ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Human
Match: SLC47A2 (solute carrier family 47 member 2 [Source:HGNC Symbol;Acc:HGNC:26439])

HSP 1 Score: 222.631 bits (566), Expect = 1.761e-62
Identity = 125/438 (28.54%), Postives = 232/438 (52.97%), Query Frame = 3 
Query:  891 INIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFL--------------ISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYT---NWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDT 2153
            +N+ G S+ +G S++ +TL +Q FGS  KK +G+ILQR  +V+ L  +      LN + IL+  +QD  ++ LT  Y+++++PGL   F + ++++YLQNQ I +P  +S  +G  VN +  Y  + V   G + +A    IS F      L YI++ K++++TW G+S     +DW   F L +P + ++ +E W +E G+ + G LS++ L AQ++ ++++T++++              I LG+ +    R+G  +G+ D    KR      L  V I  V  T+    + ++  +F+ND ++    +++L   S +   +    ++ G+L G  +Q+ GA    I YY+IG P+G +L +V +  I G+W+G++  +F   L+T  FV YT   +W     +++ +  + Q     S        K + +++ T
Sbjct:   77 VNVCGVSVGVGLSSACDTLMSQSFGSPNKKHVGVILQRGALVLLLCCLPCWALFLNTQHILLLFRQDPDVSRLTQDYVMIFIPGLPVIFLYNLLAKYLQNQKITWPQVLSGVVGNCVNGVANYALVSVLNLGVRGSAYANIISQFAQTVFLLLYIVLKKLHLETWAGWS-SQCLQDWGPFFSLAVPSMLMICVEWWAYEIGSFLMGLLSVVDLSAQAVIYEVATVTYMRHSHRLAYAAHVTRIPLGLSIGVCVRVGMALGAADTVQAKRSAVSGVLSIVGISLVLGTLISILKNQLGHIFTNDEDVIALVSQVLPVYSVFHVFEAICCVYGGVLRGTGKQAFGAAVNAITYYIIGLPLGILLTFVVRMRIMGLWLGMLACVF---LATAAFVAYTARLDWKLAAEEAKKHSGRQQQQRAESTATRPGPEKAVLSSVAT 510
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Human
Match: SLC47A1 (solute carrier family 47 member 1 [Source:HGNC Symbol;Acc:HGNC:25588])

HSP 1 Score: 217.238 bits (552), Expect = 1.343e-60
Identity = 123/427 (28.81%), Postives = 217/427 (50.82%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSE-------SNIEKIQLDETISDDINSDNSKNLSTTL 2147
            +IN+ G S+  G S++ +TL +Q +GS+  K +G+ILQR+ +V+ L         LN + IL+  +QD  ++ LT  Y+ +++P L   F +M+  +YL NQ IV P  V+     +VN +  YL +H    G   +A+   IS + +      YIL  K++  TW G+SL    +DW     L +P + ++ +E W +E G+ ++G L +++LGAQSI ++++ I +++  G  +A S R+G  +G+ D+   ++   V  L  VL    F  + LS +  +  +F+ D +I     +++   +     +       G+L G   Q VGA    I YYV+G PIG  L++    G+ G+W GI++    +A+    F+   NW     Q++       +N+ +        D ++    +NL   L
Sbjct:   80 VINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWSL-ECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGLWSGIIICTVFQAVCFLGFIIQLNWKKACQQAQVHANLKVNNVPRSGNSALPQDPLHPGCPENLEGIL 505
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Human
Match: SLC47A1 (solute carrier family 47 member 1 [Source:HGNC Symbol;Acc:HGNC:25588])

HSP 1 Score: 217.238 bits (552), Expect = 1.778e-60
Identity = 123/427 (28.81%), Postives = 217/427 (50.82%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSE-------SNIEKIQLDETISDDINSDNSKNLSTTL 2147
            +IN+ G S+  G S++ +TL +Q +GS+  K +G+ILQR+ +V+ L         LN + IL+  +QD  ++ LT  Y+ +++P L   F +M+  +YL NQ IV P  V+     +VN +  YL +H    G   +A+   IS + +      YIL  K++  TW G+SL    +DW     L +P + ++ +E W +E G+ ++G L +++LGAQSI ++++ I +++  G  +A S R+G  +G+ D+   ++   V  L  VL    F  + LS +  +  +F+ D +I     +++   +     +       G+L G   Q VGA    I YYV+G PIG  L++    G+ G+W GI++    +A+    F+   NW     Q++       +N+ +        D ++    +NL   L
Sbjct:   80 VINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWSL-ECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGLWSGIIICTVFQAVCFLGFIIQLNWKKACQQAQVHANLKVNNVPRSGNSALPQDPLHPGCPENLEGIL 505
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Human
Match: SLC47A2 (solute carrier family 47 member 2 [Source:HGNC Symbol;Acc:HGNC:26439])

HSP 1 Score: 214.157 bits (544), Expect = 2.475e-59
Identity = 125/460 (27.17%), Postives = 232/460 (50.43%), Query Frame = 3 
Query:  891 INIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQ------------------------------------NIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYT---NWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDT 2153
            +N+ G S+ +G S++ +TL +Q FGS  KK +G+ILQR  +V+ L  +      LN + IL+  +QD  ++ LT  Y+++++PGL   F + ++++YLQNQ                                     I +P  +S  +G  VN +  Y  + V   G + +A    IS F      L YI++ K++++TW G+S     +DW   F L +P + ++ +E W +E G+ + G LS++ L AQ++ ++++T++++I LG+ +    R+G  +G+ D    KR      L  V I  V  T+    + ++  +F+ND ++    +++L   S +   +    ++ G+L G  +Q+ GA    I YY+IG P+G +L +V +  I G+W+G++  +F   L+T  FV YT   +W     +++ +  + Q     S        K + +++ T
Sbjct:   77 VNVCGVSVGVGLSSACDTLMSQSFGSPNKKHVGVILQRGALVLLLCCLPCWALFLNTQHILLLFRQDPDVSRLTQDYVMIFIPGLPVIFLYNLLAKYLQNQGWLKGQEEESPFQTPGLSILHPSHSHLSRASFHLFQKITWPQVLSGVVGNCVNGVANYALVSVLNLGVRGSAYANIISQFAQTVFLLLYIVLKKLHLETWAGWSS-QCLQDWGPFFSLAVPSMLMICVEWWAYEIGSFLMGLLSVVDLSAQAVIYEVATVTYMIPLGLSIGVCVRVGMALGAADTVQAKRSAVSGVLSIVGISLVLGTLISILKNQLGHIFTNDEDVIALVSQVLPVYSVFHVFEAICCVYGGVLRGTGKQAFGAAVNAITYYIIGLPLGILLTFVVRMRIMGLWLGMLACVF---LATAAFVAYTARLDWKLAAEEAKKHSGRQQQQRAESTATRPGPEKAVLSSVAT 532
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Human
Match: SLC47A1 (solute carrier family 47 member 1 [Source:HGNC Symbol;Acc:HGNC:25588])

HSP 1 Score: 181.03 bits (458), Expect = 6.016e-49
Identity = 103/341 (30.21%), Postives = 176/341 (51.61%), Query Frame = 3 
Query:  942 TLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKG 1964
            TL    +GS+  K +G+ILQR+ +V+ L         LN + IL+  +QD  ++ LT  Y+ +++P L   F +M+  +YL NQ IV P  V+     +VN +  YL +H    G   +A+   IS + +      YIL  K++  TW G+SL    +DW     L +P + ++ +E W +E G+ ++G L +++LGAQSI ++++ I +++  G  +A S R+G  +G+ D+   ++   V  L  VL    F  + LS +  +  +F+ D +I     +++   +     +       G+L G   Q VGA    I YYV+G PIG  L++    G+ G
Sbjct:   75 TLAIATYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWSL-ECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMG 414
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Zebrafish
Match: slc47a2.1 (solute carrier family 47 member 2.1 [Source:NCBI gene;Acc:560024])

HSP 1 Score: 239.195 bits (609), Expect = 1.184e-68
Identity = 126/417 (30.22%), Postives = 229/417 (54.92%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFH-----LNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDN 2123
            +IN+ G SI  G +++ +TL +Q FGS   K++G+ILQR ++++      LACF      +N EPIL++++Q   +A L+  Y+ +++P L   F + +  RYLQNQ I++P  ++   G ++N ++ Y+ +H+ + G   +A    IS + +      YI    ++  TW+G+S  +  ++W     L LP + ++ +E W +E G  +AG +S  +LGAQS+ ++++TI+++  LG  +A S R+G  +G+ +    K   KV  + GVL+ CV  T+    +  I  +F+ + EI    ++++I   F+   D    I  GI+ G  +Q +GA   I+ YY +GFP G  L++    GI G+W+G    +F+++L   + +Y  +W     ++      +QL ET  +    +N
Sbjct:   98 VINVTGISIGSGLASACDTLISQTFGSNNLKRVGVILQRGILIL-----LLACFPCWALLINTEPILLAVRQSPNVASLSQLYVKIFMPALPAAFMYQLQGRYLQNQGIIWPQVITGAAGNILNALINYVFLHLLELGVAGSAAANTISQYSLAVFLYVYIRWKNLHKATWDGWSR-DCLQEWGAFIRLALPSMLMLCVEWWTYEIGGFLAGLISETELGAQSVVYELATIAYMFPLGFAVAASVRVGNALGAGNTERAKLSAKVALVCGVLVSCVVATLIGCTKDVIAYIFTTEEEIVSRVSQVMIMYGFFHLFDAIAGITGGIVRGAGKQLLGALCNIVGYYFVGFPTGVSLMFALSMGIIGLWIGFFGCVFLQSLFFIILIYKLDWKKATQEALIR-AGVQLTETKDESFGLEN 507
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Zebrafish
Match: BX248108.1 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:560089])

HSP 1 Score: 226.098 bits (575), Expect = 7.084e-64
Identity = 118/396 (29.80%), Postives = 217/396 (54.80%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFH-----LNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQS 2060
            +IN+ G SI  G +++ +TL +Q FGS   K++G+ILQR ++++      LACF      +N EPIL++++Q   +A L+  Y+ +++P L   F + +   YLQNQ I++P  ++   G ++N ++ Y+ +++   G   +A   AIS + +      YI    ++  TW+G+S  +  ++W     L LP + ++  E W +E G  +AG +S ++LGAQSI ++++++ ++  LG  +A   R+G  +G+ +    K   KV  + G+L+  V   V       I  +FS D +I    +++++   F    D   AI  GI+ G  +Q +GA   ++ YY +GFPIG  L++ F  GI G+W+G    +F+++L   + +Y  +W     ++
Sbjct:   96 VINVTGISIGSGLASACDTLISQTFGSNNLKRVGVILQRGILIL-----LLACFPCWALLINTEPILLAVRQSPNVASLSQLYVKIFMPALPATFMYQLQGLYLQNQGIIWPQVITGAAGNILNALINYVFLYLLDLGVPGSAAANAISQYSLAVILYTYIRCMGLHKATWDGWSW-DCLQEWGSFIRLALPSMLMLCAEWWTYEIGGFLAGLISEVELGAQSIVYELASVMYMFPLGFAVAAGVRVGNALGAGNTEQAKLSAKVSLVCGLLVSSVIAVVIAGTNNIIGYIFSKDEDIVLRVSQVMVMYGFVHLFDATSAITGGIVRGAGKQQIGALCNMVGYYCVGFPIGVSLMFAFNMGIVGLWIGFFTCVFLQSLFFIILIYRLDWKKATQEA 485
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Zebrafish
Match: slc47a3 (solute carrier family 47 member 3 [Source:ZFIN;Acc:ZDB-GENE-130530-755])

HSP 1 Score: 214.157 bits (544), Expect = 7.196e-60
Identity = 119/427 (27.87%), Postives = 235/427 (55.04%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEI-QEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSE--SNIEKIQLDETISDDINSDNSK-NLSTTLDTV 2156
            +IN+ G  I  G S + +TL +Q +G+   +++G+I Q+A+I++ L  +      +N E IL+   Q   +A ++  Y+ ++LPGL   + F++  +YLQNQ I +P+ ++  +  ++N ++ Y+ + V   G + +A    IS + +      YI    +Y +TW G+S+ +  ++W     L +P + ++  E W +E G ++AG +S ++LGAQS+ + ++ I+++  +G  +A S R+G  +G+ D+   K   KV  +  V +  V  TV    +  I  +F+ND +I Q  +T +++Y  F+ F D   A  S I+ G  +Q +GA   ++ YY IG PIG  L++  + GI G+W+G++V++F++++   + +   NW     +++  + +   + D    +D  ++    N +T +D +
Sbjct:   77 VINVLGVGIGFGLSAACDTLISQTYGAGNLQQVGVITQKAIIILLLTCLPCCAILINTESILLLAGQSPEVARVSQLYVNVFLPGLPAVYMFIVQVKYLQNQGIFWPLVITGVVANILNALINYILLFVLNMGVEGSAAANTISQYSLATILFIYIRWKGLYKETWKGWSM-DCLQEWDSFIYLAIPSMLMMCGEWWTYEIGGLLAGLISEVELGAQSVMYGLANIAYMFPIGFSIAGSVRVGNAMGAGDVAQAKLSAKVSIMCAVSVAVVLATVIGCSKNVIARIFTNDKDIIQRVATVMVLYTPFHIF-DATTAAGSSIVKGLGKQKLGAICNLLGYYGIGCPIGIPLMFAAKMGIFGLWIGLLVSVFLQSIFFIVLLVKLNWKKASEEAQIRAGVAIRRTDGASQEDGENEGCDVNDATDVDVL 501
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Zebrafish
Match: slc47a3 (solute carrier family 47 member 3 [Source:ZFIN;Acc:ZDB-GENE-130530-755])

HSP 1 Score: 207.994 bits (528), Expect = 2.350e-59
Identity = 113/385 (29.35%), Postives = 216/385 (56.10%), Query Frame = 3 
Query:  891 INIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEI-QEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWD 2042
            IN+ G  I  G S + +TL +Q +G+   +++G+I Q+A+I++ L  +      +N E IL+   Q   +A ++  Y+ ++LPGL   + F++  +YLQNQ I +P+ ++  +  ++N ++ Y+ + V   G + +A    IS + +      YI    +Y +TW G+S+ +  ++W     L +P + ++  E W +E G ++AG +S ++LGAQS+ + ++ I+++  +G  +A S R+G  +G+ D+   K   KV  +  V +  V  TV    +  I  +F+ND +I Q  +T +++Y  F+ F D      S I+ G  +Q +GA   ++ YY IG PIG  L++  + GI G+W+G++V++F++++   + +   NW 
Sbjct:    1 INVLGVGIGFGLSAACDTLISQTYGAGNLQQVGVITQKAIIILLLTCLPCCAILINTESILLLAGQSPEVARVSQLYVNVFLPGLPAVYMFIVQVKYLQNQGIFWPLVITGVVANILNALINYILLFVLNMGVEGSAAANTISQYSLATILFIYIRWKGLYKETWKGWSM-DCLQEWDSFIYLAIPSMLMMCGEWWTYEIGGLLAGLISEVELGAQSVMYGLANIAYMFPIGFSIAGSVRVGNAMGAGDVAQAKLSAKVSIMCAVSVAVVLATVIGCSKNVIARIFTNDKDIIQRVATVMVLYTPFHIF-DATTVAGSSIVKGLGKQKLGAICNLLGYYGIGCPIGIPLMFAAKMGIFGLWIGLLVSVFLQSIFFIVLLVKLNWK 383
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Zebrafish
Match: slc47a4 (solute carrier family 47 member 4 [Source:ZFIN;Acc:ZDB-GENE-130530-865])

HSP 1 Score: 182.956 bits (463), Expect = 1.586e-48
Identity = 123/473 (26.00%), Postives = 233/473 (49.26%), Query Frame = 3 
Query:  891 INIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFG-FQSAAV---CQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFS---GILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKI---QLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENL----INDEPELNASRK 2267
            IN+   +  LG + + +TL +Q FGS+   ++GIILQR ++++TL  +      +N +P+L+ L Q+  +A +   Y+++YLP +   F + +   YLQNQ ++ P   +S +  V N+I  Y  ++ + FG + SAA     Q  + F +F     +I   K++  TW G+SL  + +DW     L +P   +   E W +E G  +AG LS + L AQ +   ++ I+++I LG+  A   R+G  +G+ +  +     KV  +   +I  +   V  S +  I  +F++D  I E  ++LL   + Y  L  F  I     G+L G  +Q + A A +  YY IG P   +L++     + G W+G+++A+F+ A+   + ++  NW  +  ++ +   K      + T++ +  S++  +    +   E           ++ + S+ + E L    + +EP +    +
Sbjct:   83 INVTAAATGLGLALACDTLVSQTFGSKNLLRVGIILQRGIVILTLFSLPCWALLVNTQPLLLYLGQEPEVARIAQLYVVVYLPAIPAMFLYQLQLSYLQNQGVIKPQMYASAVANVANVIANYFLLYWWDFGVYGSAAANTFAQVFNCFALFC----FIRWQKLHEKTWGGWSL-EALQDWGSYMKLAIPSTLMTCFEWWIYEVGGFLAGMLSEVDLAAQHVVIMLAYINYMIPLGMQGAACVRVGNALGAGETAAAILTSKVSLISAAVIAIIQGFVLGSTKTVIGYIFTSDESITELVSQLL---NIYCPLQFFNGILCVGMGVLLGTGQQKIAAIANLFGYYCIGLPSSIVLMFTAGLQVAGFWLGLLIAVFLLAIFFTVAIFKLNWKKMTEEAIARTGKSANGAANGTMTTEFCSNHRNSFYQVVLNAE-------NGNGYMVVSSQDQDERLNSTAVPEEPNVTGVEE 540
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Xenopus
Match: tmed6 (transmembrane p24 trafficking protein 6 [Source:Xenbase;Acc:XB-GENE-967876])

HSP 1 Score: 207.994 bits (528), Expect = 1.637e-57
Identity = 136/472 (28.81%), Postives = 243/472 (51.48%), Query Frame = 3 
Query:  882 HNIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGL----FFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQT 2285
            ++I+ + G SI LG  ++ +T F+QI+G +  K +G++LQR +++++L       F +N + IL+ L QD  +A L   Y++  +P L    FF+ +     RYLQNQ I++P  V SF+  ++N IL Y+ + V + G   AA+   +S          YI I K+++DTW G++     +DW   F L LP + ++ L+ W FE   +++G +++++LG QSI  QI  +   ISL + LA+  R+G Y+G+ +    KR  ++  +       +   + +  R++I  +F+ND  I    + ++   + +  +     +F GIL G   Q VGA+  +  Y +I FP+   L++  + G+KG W GI   L V  +   ++++  NW  +   +E  +E+  L E       +  +  ++++ D  E L      N +FI    E   E L   E E  + +K+ I +T
Sbjct:   71 NSIVILAGQSIGLGICSACDTFFSQIYGGKNLKLIGVVLQRGILILSLSCFPCWAFFVNTKNILLLLGQDPSVARLAELYVLTCIPALVGINFFNLEI----RYLQNQGIIWPQVVVSFLACIINGILNYVLLFVLKIGVIGAAIAVTVSIVSKVIILFFYIWIRKIHVDTWPGWT-KECLKDWGSFFALALPTMIMLSLKWWTFEIAIILSGLINLVELGGQSIMHQIMNLLNKISLALSLASCIRVGTYLGAGETEQAKRSARLSFVISAFPVFLGVGLLIGLRREIASIFTNDSSILFLVSDIMPLCAVFQIVGSACNLFYGILRGIGMQKVGAFVTVGGYLLIVFPMAVPLMFPAKLGVKGFWTGINAGLAVMDIVFVIYLWKANWKLI---TEKALERAGLKELKEKGPTALEANGIASS-DHFE-LNNYDTMNSAFI---GEQHLERLFKHE-EKQSMKKLMIRRT 528
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Xenopus
Match: slc47a2 (solute carrier family 47 (multidrug and toxin extrusion), member 2 [Source:NCBI gene;Acc:100125051])

HSP 1 Score: 199.519 bits (506), Expect = 2.632e-54
Identity = 115/397 (28.97%), Postives = 207/397 (52.14%), Query Frame = 3 
Query:  924 FSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLS-FRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNI-EKIQLDETISDD 2108
             S + + L  Q FG    K +GIILQR ++++ L         +N E IL+  +QD  ++ LT  Y++++LP L   F + ++++YLQNQ I+YP  ++ FI  + N +  Y+ ++V   G   +A    +S F+       YI+  ++Y DTW G+S    F +W     L +  + ++ +E W FE    +AG L ++ L AQ+I +Q++ + +LI LG+ +A S R+G  +G+ +    KR   V  L    +C +   + L+  +  +  +F++DP I    + +L   S     D   A   GIL G  +  VGA +  + YYVIG P+G  L++  + GI G W GI+     +++   +FV+  +W     ++++   E++++ + I + 
Sbjct:  107 LSMAGDFLVLQTFGGSNLKLVGIILQRGILILLLFCFPCWALLINTESILLLFRQDPEVSKLTQIYVLIFLPALPAAFLYQLLAKYLQNQGIIYPQVLTGFIANIFNALFNYILLYVLGLGVMGSACANTVSQFIQMILLFLYIVWRRLYADTWGGWSQ-ACFEEWGAFIRLAVASMLMLCIEWWAFEISMFLAGVLGMVDLAAQAIIYQVAIVVYLIPLGLCIAGSIRVGHGLGAGNTEQAKRSALV-VLCMTELCALLSGILLATLKDVVAYIFTSDPNIVALVSYVLPVYSACLLFDACVAACGGILRGSGKLKVGAISHTVGYYVIGLPLGISLMFAAKLGIIGFWFGILACGIAQSIFLIIFVFKIDWKRASEEAQTRASERVEIPQKIDNK 501
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Xenopus
Match: ccdc85a (coiled-coil domain containing 85A [Source:Xenbase;Acc:XB-GENE-954470])

HSP 1 Score: 165.236 bits (417), Expect = 7.698e-43
Identity = 115/370 (31.08%), Postives = 196/370 (52.97%), Query Frame = 3 
Query:  879 PHNIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFH-----LNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLF--GVLICCVFCTVTL--SFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIK 1961
             + +I + G S+ LG S++ +TL +QIFG +  K +GIILQR ++++     FLACF      +N E IL+  KQD  +A  + +   + L              Y+  Q IVY   + SF+  ++N I+ Y+ + V + G   +A    I+ F        YI + +++++TW G+S+    +DW     L +P + +V +E W +E G +++G L +++LGAQS+ +Q+ T +++I  GI +ATS R+G  +G+ ++   K    V  L     L   +F  + +  SF+ +   +F+ND  +    T LL+Y+SF  F      +  GIL G  RQ +GA   ++ YY+IG P+   L++    GIK
Sbjct:   92 ANAVIAVTGLSVGLGLSSACDTLISQIFGGKNLKLIGIILQRGILIL-----FLACFPCWALFINTENILLLFKQDPKVASSSRQCKSVSLNQTKMS--------YVIFQGIVYVQIIVSFVSNIINCIVNYVFLFVLRLGVIGSAWANTIAQFSQCLLIFLYIRVKRLHVNTWGGWSI-ECLQDWSSFISLAIPSMLMVCIEWWTYEIGNLMSGLLGVVELGAQSVIYQVVTTAYMIPFGIGMATSVRVGNALGAGNIEQAKTSTTVAFLVTGASLPAVIFVDILMLASFKNQFAYIFTNDRWV---FTFLLLYLSF-SF-----CVAGGILRGTGRQKIGAIINMVGYYLIGLPLAAALMFAVNIGIK 438
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Xenopus
Match: ccdc85a (coiled-coil domain containing 85A [Source:Xenbase;Acc:XB-GENE-954470])

HSP 1 Score: 160.229 bits (404), Expect = 1.581e-41
Identity = 113/373 (30.29%), Postives = 197/373 (52.82%), Query Frame = 3 
Query:  879 PHNIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACF-----HLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLF--GVLICCVFCTVTL--SFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMW 1970
             + +I + G S+ LG S++ +TL +QIFG +  K +GIILQR +++     +FLACF      +N E IL+  KQD  +A  + +   + L              Y+  Q IVY   + SF+  ++N I+ Y+ + V + G   +A    I+ F        YI + +++++TW G+S +   +DW     L +P + +V +E W +E G +++G L +++LGAQS+ +Q+ T ++++     +ATS R+G  +G+ ++   K    V  L     L   +F  + +  SF+ +   +F+ND  +    T LL+Y+SF  F      +  GIL G  RQ +GA   ++ YY+IG P+   L++    GIKG++
Sbjct:   64 ANAVIAVTGLSVGLGLSSACDTLISQIFGGKNLKLIGIILQRGILI-----LFLACFPCWALFINTENILLLFKQDPKVASSSRQCKSVSLNQTKMS--------YVIFQGIVYVQIIVSFVSNIINCIVNYVFLFVLRLGVIGSAWANTIAQFSQCLLIFLYIRVKRLHVNTWGGWS-IECLQDWSSFISLAIPSMLMVCIEWWTYEIGNLMSGLLGVVELGAQSVIYQVVTTAYMVR-SASMATSVRVGNALGAGNIEQAKTSTTVAFLVTGASLPAVIFVDILMLASFKNQFAYIFTNDRWV---FTFLLLYLSF-SF-----CVAGGILRGTGRQKIGAIINMVGYYLIGLPLAAALMFAVNIGIKGIY 412
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Xenopus
Match: ENSXETT00000000956.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:2:92535169:92537612:-1 gene:ENSXETG00000006135.1 transcript:ENSXETT00000000956.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 3.298e-11
Identity = 40/147 (27.21%), Postives = 69/147 (46.94%), Query Frame = 3 
Query: 1743 LFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQS-----------ESNIEKIQLDETISDDINSDNSKNLSTTLD 2150
            +F+ D EI    ++LL+    +   D       G+L G  +Q +GA    I YY+ GFPIG  L++  + G+ G+W G+++ +F++A     F    NW  V  ++           E+  +  QL+ +      S  S N+S  +D
Sbjct:   28 IFTPDREIVALVSRLLLIFGPFHLCDAMACTCGGVLRGTGKQKIGAILNAIGYYLFGFPIGISLMFAAKLGVMGLWSGMLICVFLQASFFLTFNLRLNWSKVCEEAQVRAGVKPKKEEAEPDVSQLEHSYITQKYSAFSTNVSRDID 174
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Mouse
Match: Slc47a1 (solute carrier family 47, member 1 [Source:MGI Symbol;Acc:MGI:1914723])

HSP 1 Score: 205.297 bits (521), Expect = 1.440e-56
Identity = 113/410 (27.56%), Postives = 212/410 (51.71%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSE--SNIE-KIQLDETISDD 2108
            +IN+ G S+  G S++ +TL +Q +GS+  K +G+ILQR  +++ L         +N E IL+  +QD  ++ LT  Y+++++P L   F + +  +YL NQ IV P  ++     +VN +  Y+ ++    G   +A+   IS F +      YIL  +++  TW G+S     +DW     L +P + ++ +E W +E G+ ++G L +++LGAQSI ++++ I ++I  G  +A + R+G  +G+ ++   K+   +  +   L    FC + L  +  +  +F+ D +I     +++   +     +       GIL G   Q VGA    I YYVIG PIG  L++  + G+ G+W GI++    +      F+   NW     Q++  +N++  + L+  +S +
Sbjct:   80 VINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMIFIPALPAAFLYTLQVKYLLNQGIVLPQIMTGIAANLVNALANYVFLYHLHLGVMGSALANTISQFALAIFLFLYILWRRLHQATWGGWS-WECLQDWASFLRLAIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSITYELAIIVYMIPSGFSVAANVRVGNALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDRDIVALVAQVIPIYAVSHLFEGLACTCGGILRGTGNQKVGAIVNAIGYYVIGLPIGIALMFAAKLGVIGLWSGIIICTTCQTTCFLAFIARLNWKRACQQAQVHANLKVNVALNSAVSHE 488
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Mouse
Match: Slc47a2 (solute carrier family 47, member 2 [Source:MGI Symbol;Acc:MGI:3588190])

HSP 1 Score: 203.371 bits (516), Expect = 6.571e-56
Identity = 111/398 (27.89%), Postives = 215/398 (54.02%), Query Frame = 3 
Query:  885 NIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTL-----SFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSE 2063
            +++N+ G S+  G +++ +TL +Q FG +  K++G+ILQR ++++ L         LN E +L+ L+QD  +A L   Y+++ +P L   F F + +RYLQ+Q I+ P  +      VVN+ +    ++    G   +A     S F + A    Y+   ++++ TW G++    F++W     L +P +F+V +E W FE GT +AG +++ +LGAQ++ ++++++++++  G  +A S R+G  +G+ +    +      S   VL+C   C + +     + +  +  +F+ND +I    ++++   + +   D       G+L G  +Q +GA    I YY  GFPIG  L++  + GI G+W G++V +  +A S  +++  TNW  V  Q++
Sbjct:   88 SVVNVTGISVGTGLASACDTLMSQSFGGKNLKRVGVILQRGILILLLCCFPCWAIFLNTERLLLLLRQDPDVARLAQVYVMICIPALPAAFLFQLQTRYLQSQGIIMPQVIVGIAANVVNVGMNAFLLYALDLGVVGSAWANTTSQFFLSALLFLYVWWKRIHIHTWGGWT-RECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFLAGLVNVTELGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQAR-----CSCTTVLLCAGVCALLVGILLAALKDVVAYIFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRGTGKQKIGAVLNTIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVSFQAFSYLIYILRTNWSRVAEQAQ 479
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Mouse
Match: Slc47a2 (solute carrier family 47, member 2 [Source:MGI Symbol;Acc:MGI:3588190])

HSP 1 Score: 201.06 bits (510), Expect = 7.616e-56
Identity = 111/396 (28.03%), Postives = 213/396 (53.79%), Query Frame = 3 
Query:  885 NIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTL-----SFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQ 2057
            +++N+ G S+  G +++ +TL +Q FG +  K++G+ILQR ++++ L         LN E +L+ L+QD  +A L   Y+++ +P L   F F + +RYLQ+Q I+ P  +      VVN+ +    ++    G   +A     S F + A    Y+   ++++ TW G++    F++W     L +P +F+V +E W FE GT +AG +++ +LGAQ++ ++++++++++  G  +A S R+G  +G+ +    +      S   VL+C   C + +     + +  +  +F+ND +I    ++++   + +   D       G+L G  +Q +GA    I YY  GFPIG  L++  + GI G+W G++V +  +A S  +++  TNW  V  Q
Sbjct:   88 SVVNVTGISVGTGLASACDTLMSQSFGGKNLKRVGVILQRGILILLLCCFPCWAIFLNTERLLLLLRQDPDVARLAQVYVMICIPALPAAFLFQLQTRYLQSQGIIMPQVIVGIAANVVNVGMNAFLLYALDLGVVGSAWANTTSQFFLSALLFLYVWWKRIHIHTWGGWT-RECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFLAGLVNVTELGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQAR-----CSCTTVLLCAGVCALLVGILLAALKDVVAYIFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRGTGKQKIGAVLNTIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVSFQAFSYLIYILRTNWSRVAEQ 477
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Mouse
Match: Slc47a1 (solute carrier family 47, member 1 [Source:MGI Symbol;Acc:MGI:1914723])

HSP 1 Score: 100.908 bits (250), Expect = 1.298e-23
Identity = 54/179 (30.17%), Postives = 96/179 (53.63%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWK 1424
            +IN+ G S+  G S++ +TL +Q +GS+  K +G+ILQR  +++ L         +N E IL+  +QD  ++ LT  Y+++++P L   F + +  +YL NQ IV P  ++     +VN +  Y+ ++    G   +A+   IS F +      YIL  +++  TW G+S     +DW 
Sbjct:   30 VINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMIFIPALPAAFLYTLQVKYLLNQGIVLPQIMTGIAANLVNALANYVFLYHLHLGVMGSALANTISQFALAIFLFLYILWRRLHQATWGGWS-WECLQDWA 207
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Mouse
Match: Slc47a1 (solute carrier family 47, member 1 [Source:MGI Symbol;Acc:MGI:1914723])

HSP 1 Score: 70.0922 bits (170), Expect = 2.576e-13
Identity = 34/102 (33.33%), Postives = 61/102 (59.80%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQ 1193
            +IN+ G S+  G S++ +TL +Q +GS+  K +G+ILQR  +++ L         +N E IL+  +QD  ++ LT  Y+++++P L   F + +  +YL NQ
Sbjct:   80 VINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMIFIPALPAAFLYTLQVKYLLNQ 181
[Close]
BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Match: sp|A1L1P9|S47A1_DANRE (Multidrug and toxin extrusion protein 1 OS=Danio rerio OX=7955 GN=slc47a1 PE=2 SV=1)

HSP 1 Score: 239.195 bits (609), Expect = 8.935e-68
Identity = 126/417 (30.22%), Postives = 229/417 (54.92%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFH-----LNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDN 2123
            +IN+ G SI  G +++ +TL +Q FGS   K++G+ILQR ++++      LACF      +N EPIL++++Q   +A L+  Y+ +++P L   F + +  RYLQNQ I++P  ++   G ++N ++ Y+ +H+ + G   +A    IS + +      YI    ++  TW+G+S  +  ++W     L LP + ++ +E W +E G  +AG +S  +LGAQS+ ++++TI+++  LG  +A S R+G  +G+ +    K   KV  + GVL+ CV  T+    +  I  +F+ + EI    ++++I   F+   D    I  GI+ G  +Q +GA   I+ YY +GFP G  L++    GI G+W+G    +F+++L   + +Y  +W     ++      +QL ET  +    +N
Sbjct:   98 VINVTGISIGSGLASACDTLISQTFGSNNLKRVGVILQRGILIL-----LLACFPCWALLINTEPILLAVRQSPNVASLSQLYVKIFMPALPAAFMYQLQGRYLQNQGIIWPQVITGAAGNILNALINYVFLHLLELGVAGSAAANTISQYSLAVFLYVYIRWKNLHKATWDGWSR-DCLQEWGAFIRLALPSMLMLCVEWWTYEIGGFLAGLISETELGAQSVVYELATIAYMFPLGFAVAASVRVGNALGAGNTERAKLSAKVALVCGVLVSCVVATLIGCTKDVIAYIFTTEEEIVSRVSQVMIMYGFFHLFDAIAGITGGIVRGAGKQLLGALCNIVGYYFVGFPTGVSLMFALSMGIIGLWIGFFGCVFLQSLFFIILIYKLDWKKATQEALIR-AGVQLTETKDESFGLEN 507
[Close]
BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Match: sp|Q5RFD2|S47A1_PONAB (Multidrug and toxin extrusion protein 1 OS=Pongo abelii OX=9601 GN=SLC47A1 PE=2 SV=1)

HSP 1 Score: 221.476 bits (563), Expect = 1.961e-61
Identity = 122/427 (28.57%), Postives = 218/427 (51.05%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSE-------SNIEKIQLDETISDDINSDNSKNLSTTL 2147
            +IN+ G S+  G S++ +TL +Q +GS+  K +G+ILQR+ +++ L         LN + IL+  +QD  ++ LT  Y+ +++P L   F +M+  +YL NQ IV P  V+     +VN +  YL +H    G   +A+   IS + +      YIL  K++  TW G+SL    +DW     L +P + ++ +E W +E G+ ++G L +++LGAQSI ++++ I +++  G  +A S R+G  +G+ D+   ++   V  L  VL    F  + LS +  +  +F+ D +I     +++   +     +       G+L G   Q VGA    I YYV+G PIG  L++  + G+ G+W GI++    +A+    F+   NW     Q++       +N+ +        D ++    +NL   L
Sbjct:   80 VINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALILLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGAIGSALANLISQYTLALLLFFYILGKKLHQATWGGWSL-ECLQDWASFLHLAVPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATKLGVMGLWSGIIICTVFQAVCFLGFIIQLNWKKACQQAQVHANLKVNNVPRSGNSALPQDPLHPGCPENLEGIL 505
[Close]
BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Match: sp|Q5R7E4|S47A2_PONAB (Multidrug and toxin extrusion protein 2 OS=Pongo abelii OX=9601 GN=SLC47A2 PE=2 SV=1)

HSP 1 Score: 219.164 bits (557), Expect = 1.347e-60
Identity = 121/410 (29.51%), Postives = 223/410 (54.39%), Query Frame = 3 
Query:  891 INIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFL--------------ISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYT---NWDYVFNQSESN 2069
            +N+ G S+ +G S++ +TL +Q FGS  KK +G+ILQR  +V+ L  +      LN + IL+  +QD  ++ LT  Y+++++PGL   F + ++++YLQNQ I +P  +S  +G  VN +  Y  + V   G + +A    IS F      L YI++ K++++TW G+S     +DW   F L +P + ++ +E W +E G+ + G LS++ L AQ++ ++++T++++              I LG+ +    R+G  +G+ D    KR      L  V I  V  T+    + ++  +F+ND ++    +++L   S +   +    ++ G+L G  +Q+ GA    I YY+IG P+G +L +V +  I G+W+G++  +F   L+T  FV YT   +W     +++ +
Sbjct:   77 VNVCGVSVGVGLSSACDTLMSQSFGSPNKKHVGVILQRGALVLLLCCLPCWALFLNTQHILLLFRQDPEVSRLTQDYVMIFIPGLPVIFLYNLLAKYLQNQKITWPQVLSGVVGNCVNGVANYALVSVLNLGVRGSAYANIISQFAQTVFLLLYIVLKKLHLETWAGWS-SQCLQDWGPFFSLAVPSMLMICVEWWAYEIGSFLMGLLSVVDLSAQAVIYEVATVTYMRHSHHLAYTAHVARIPLGLSIGVCVRVGMALGAADTVQAKRSAVSGVLSIVGISLVLGTLISILKNQLGHIFTNDEDVIALVSQVLPVYSVFHVFEAICCVYGGVLRGTGKQAFGAAVNAITYYIIGLPLGILLTFVVRMRIMGLWLGMLACVF---LATAAFVAYTARLDWKLAAEEAKKH 482
[Close]
BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Match: sp|A7KAU2|S47A1_RABIT (Multidrug and toxin extrusion protein 1 OS=Oryctolagus cuniculus OX=9986 GN=SLC47A1 PE=2 SV=1)

HSP 1 Score: 218.394 bits (555), Expect = 2.385e-60
Identity = 122/413 (29.54%), Postives = 220/413 (53.27%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNS 2126
            +IN+ G S+  G S++ +TL +Q +GS   K +G+ILQR  +++ L  +      LN + IL+  +QD  ++ LT  Y+ +++P L   F + +  +YL NQ IV P  V+     +VN +  YL ++    G   +A+   ++ F +      YIL SKVY  TW G+S L   +DW   F L +P + ++ +E W +E G+ ++G L +++LGAQS+ ++++ I ++I +G+ +A + R+G  +G+ ++   K+   V  L   LI  VFC + LS +  +  +F++D +I     ++    +     +       GIL G   Q  GA    I YYV+G PIG  L++  + G+ G+W+GI+V    +A+    F+   NW     Q+     ++  + T++   N +++
Sbjct:   79 VINVMGVSVGFGLSSACDTLISQTYGSRNLKHVGVILQRGSLILLLCCLPCWALFLNTQHILLLFRQDPAVSRLTQTYVTIFIPALPATFLYTLQVKYLLNQGIVLPQVVTGVAANLVNALANYLFVYQLHLGVMGSALANTVAQFTLALLLFLYILRSKVYQATWGGWS-LECLQDWASFFRLAIPSMLMLCMEWWAYEIGSFLSGILGMVELGAQSVTYELAVIVYMIPMGLSVAVNVRVGNALGAGNIEQAKKSSAVALLVTELIAVVFCVMLLSCKDLVGYIFTSDRDIIALVAQVTPIYAVSHLFESLAGTSGGILRGSGNQKFGAIVNAIGYYVVGLPIGIALMFAAKLGVIGLWLGIVVCAVSQAVCFLGFIARLNWTKACQQA-----RVHANLTVNTASNGNSA 485
[Close]
BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Match: sp|Q96FL8|S47A1_HUMAN (Multidrug and toxin extrusion protein 1 OS=Homo sapiens OX=9606 GN=SLC47A1 PE=1 SV=1)

HSP 1 Score: 217.238 bits (552), Expect = 6.452e-60
Identity = 123/427 (28.81%), Postives = 217/427 (50.82%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSE-------SNIEKIQLDETISDDINSDNSKNLSTTL 2147
            +IN+ G S+  G S++ +TL +Q +GS+  K +G+ILQR+ +V+ L         LN + IL+  +QD  ++ LT  Y+ +++P L   F +M+  +YL NQ IV P  V+     +VN +  YL +H    G   +A+   IS + +      YIL  K++  TW G+SL    +DW     L +P + ++ +E W +E G+ ++G L +++LGAQSI ++++ I +++  G  +A S R+G  +G+ D+   ++   V  L  VL    F  + LS +  +  +F+ D +I     +++   +     +       G+L G   Q VGA    I YYV+G PIG  L++    G+ G+W GI++    +A+    F+   NW     Q++       +N+ +        D ++    +NL   L
Sbjct:   80 VINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWSL-ECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGLWSGIIICTVFQAVCFLGFIIQLNWKKACQQAQVHANLKVNNVPRSGNSALPQDPLHPGCPENLEGIL 505
[Close]
BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Match: A0A0H3YKK1 (Multidrug and toxin extrusion protein OS=Schmidtea mediterranea OX=79327 GN=slc47a-1 PE=2 SV=1)

HSP 1 Score: 1020.76 bits (2638), Expect = 0.000e+0
Identity = 526/564 (93.26%), Postives = 529/564 (93.79%), Query Frame = 3 
Query:  882 HNIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFG--------------------VLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIK-------------GMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMXXXXXXXXXXVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY 2474
            ++IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMT+SSFIGTV NLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFG                    VLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIK             GMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIV NETERFYQLISARVCNISSY
Sbjct:   85 NSIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTISSFIGTVFNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGGMNIWLLNFMINMKPPIIILVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGLINSFKAFCLFLGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVLNETERFYQLISARVCNISSY 648

HSP 2 Score: 138.658 bits (348), Expect = 3.922e-30
Identity = 68/73 (93.15%), Postives = 70/73 (95.89%), Query Frame = 1 
Query:  682 MDNFPTVLSNSKEKSRTKLKLMKMFQSVCCLNFSLKDFKQEIFSLMSIFIPSVLTTFFRMLNPVISLIILSTY 900
            MDNFPTVLSNSKEKSRTKLKLMKMFQSVCCLNFSLKDFKQEIFSLMSIFIPSVLTTFFRMLNPVISLI+   +
Sbjct:    1 MDNFPTVLSNSKEKSRTKLKLMKMFQSVCCLNFSLKDFKQEIFSLMSIFIPSVLTTFFRMLNPVISLIMCGHF 73
[Close]
BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Match: A0A0H3YJN2 (Multidrug and toxin extrusion protein OS=Schmidtea mediterranea OX=79327 GN=slc47a-2 PE=2 SV=1)

HSP 1 Score: 394.815 bits (1013), Expect = 8.093e-125
Identity = 206/500 (41.20%), Postives = 315/500 (63.00%), Query Frame = 3 
Query: 1017 MTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDD------------INSDNSKNLSTTLDT---------VERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVN--------KNMXXXXXXXXXXVITMFLFAIIIRVYSTMLWHFPCVIVSNETER 2429
            MTL+Y+ L CFHLN+EP LI LKQ+  +A L+ +YI  Y+PGLFFDFQF+ ISRYLQNQNIVYPM +SSF+G V + + QY+AI+VY +  +++A+ Q +S FVMF  +L YILISKVY DTWNGFSL ++  +WK++F+LG+PGI ++ LEEW FE  T+++GTL  IQLGAQSIAFQ ST+SF++++G+ +ATS R+GQ++GS+++ ++K   +   + G++   + CT+ L  R  I  +FS++ EIQ E ++LL +I+F  F D+   I SGIL  C RQ +GA  M  CYY+IG PIG I V+V +  IKGMW+G+++AL ++     + V+ TNW+   +++ +NIE ++  ++  D+             N D ++N    + +          E++     K K+F +    SE   +       N SR + IY  ++         +  +IK+ +  L+V+ + + AI+IR+Y     +  C+  S E  R
Sbjct:    1 MTLLYLVLVCFHLNIEPFLILLKQNPSVAELSTRYITYYIPGLFFDFQFLTISRYLQNQNIVYPMVISSFLGNVFSAVSQYVAIYVYGYKLEASAILQGVSCFVMFILQLAYILISKVYKDTWNGFSLKDALDNWKILFVLGIPGILMIALEEWNFEIATIISGTLDGIQLGAQSIAFQCSTVSFMMTMGLAIATSIRVGQFLGSREIDNLKTAYRTSFVVGMVCSAISCTLILVLRNYIAAMFSSNKEIQAEGSELLFFIAFMQFADMIAGITSGILKACGRQVIGAAIMFACYYLIGIPIGIIFVFVIKLQIKGMWIGLIIALVIEGFVFSVLVFRTNWEVECDKAMANIEDVEFTKSFYDESAEKSQGAFTKYFNEDMTENCPLIVKSDYEGDAYWVREKIHNPEKKIKNFKRPRITSEVHIM-----PTNRSRSLMIYTKEIYNIDTDQPLRKTIIKRAVTFLVVLLLVICAILIRIYLPKSLYVSCIPDSEEARR 495
[Close]
BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Match: A0A0H3YJI2 (Multidrug and toxin extrusion protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=slc47a-4 PE=2 SV=1)

HSP 1 Score: 365.925 bits (938), Expect = 1.006e-112
Identity = 209/557 (37.52%), Postives = 326/557 (58.53%), Query Frame = 3 
Query:  822 HFYSKCFDNIFQNAQPGDQPHNIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNS-KNLSTTLDTVERL--------------LKRFWKNKSFIKIPSESE----TENLIN---DEPELNASRKITIYQTQVNKNMXXXXXXXXXXVITMFLFAIIIRVYSTMLWHFPCVIVSNETE 2426
            H   K FD            + +IN+FG S+DLGFST+ +TLFA+I+GS  + K+G++LQ+A++VMT++Y  L CFHLN+EP+LI L+QD+ I+ L AKY+++YLPGLFFDFQF+ I+RYLQNQN+VYPM VSSFIG + N++ QY+AI+  +FG +++A+ Q +S  VMF+ +L +++ SK+Y  TW G   LN+   W + F LG+PGI ++G+EEW FE G  ++G LS +QLGAQSIAFQI  I + +  G+ +A + R GQ++G+   +      K   L  + +     T+ L+FR  +  +F+ND EI   + K+L+ +    FLD   +  SGI   C +Q  GA  MI   Y++G P+G IL+YV  T I+G W+G+++AL  +     + ++  +W+    +++S  +    D  I   I+ D S +    TL+  + L              LK   KN    KI         +E LI+   D P L  + K T+++T V +           + + +F  +I +++Y    ++ PC  +SN+T 
Sbjct:   57 HLTKKEFD-------AASLANALINVFGVSVDLGFSTACDTLFARIYGSRNRHKLGLMLQKAILVMTILYFILGCFHLNIEPVLILLQQDVEISRLAAKYVVIYLPGLFFDFQFLAIARYLQNQNVVYPMMVSSFIGCIFNVVFQYIAIYQLKFGIEASALIQGLSCCVMFSLQLVHLIKSKIYKPTWQGIEFLNALEGWGIFFKLGIPGIIMLGVEEWMFEIGNFISGALSDVQLGAQSIAFQIEMICYTLHSGLSIAVAIRAGQFLGANKPKEASLTGKAIILIELSLSTFTATIILAFRNYLPFVFTNDEEIINLAQKILLILVPIQFLDAGCSTASGIFRACGKQVKGAIIMICGCYLLGIPVGIILIYVVGTDIQGFWIGLVIALVAEVSIFFIVIFRIDWNNEALKAQSTCK----DTNIVSPIDKDKSYEKYPDTLEDSKLLKSESDSEEEEHESVLKTVRKNS---KITGRRSIGGISEVLIDSCRDYPNLRMNYK-TMHKTIVKRIT------LTTITLILFCSSIFVKIYLPEKYYIPC--ISNQTN 590
[Close]
BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Match: G4VIQ3 (Multidrug and toxin extrusion protein OS=Schistosoma mansoni OX=6183 GN=Smp_135490 PE=3 SV=1)

HSP 1 Score: 326.635 bits (836), Expect = 2.260e-99
Identity = 171/412 (41.50%), Postives = 261/412 (63.35%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSF-RQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSD 2120
            IINIFG SID GFS++ +TLF+Q +GS  +K MG +LQRA+ V+ L+YM L C HLN+E +L+ L Q+  IA LT++YI  +LPGL FDF F+  +RYLQ+QNI+ PM  S+F GTV N++ QY  +    +G +++AVC ++S   MF CELGYIL SKVY +TWNGF+L ++F +W + F LG+PG+ +VGLEEW FE  T++AGTL  + LGAQ+I FQI +I +++ LG++ A + R+GQ +G+ D     R +   +L  + I  +F  + + F RQ I  +F++D ++   +++LL  +  + F + F  I   IL  C RQS+GA  + + YY  G PI  +L Y    GI G W+G+ +   +  +   +    T+W     ++ +N+ +  L    +++IN  
Sbjct:   35 IINIFGLSIDTGFSSACDTLFSQAYGSRNRKLMGTLLQRALCVVCLMYMTLVCIHLNIETVLLLLGQNPLIASLTSEYIAYFLPGLGFDFLFLTFARYLQSQNIIQPMVYSTFTGTVFNILAQYYFVVRLNYGLRASAVCLSLSFGCMFLCELGYILASKVYKETWNGFNLNSAFSNWGIFFKLGIPGVLMVGLEEWCFEIMTIMAGTLGSVTLGAQAIVFQIQSIIYMVPLGLFTAVNIRVGQKLGAFDPVG-ARYVYTTALTIISIVALFTGLPVVFLRQYIPYMFTSDEKVCLLASRLLPMLLLFQFFEGFAGISEAILLACGRQSIGAITIFLGYYCTGMPIAALLTYQTSLGILGSWIGLTIGFGLTTMVYTILALRTDWTEQVRRARNNVTE-TLSVYSTNNINEQ 444
[Close]
BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Match: A0A3Q0KMD5 (Multidrug and toxin extrusion protein OS=Schistosoma mansoni OX=6183 PE=3 SV=1)

HSP 1 Score: 327.791 bits (839), Expect = 5.213e-98
Identity = 171/412 (41.50%), Postives = 261/412 (63.35%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSF-RQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSD 2120
            IINIFG SID GFS++ +TLF+Q +GS  +K MG +LQRA+ V+ L+YM L C HLN+E +L+ L Q+  IA LT++YI  +LPGL FDF F+  +RYLQ+QNI+ PM  S+F GTV N++ QY  +    +G +++AVC ++S   MF CELGYIL SKVY +TWNGF+L ++F +W + F LG+PG+ +VGLEEW FE  T++AGTL  + LGAQ+I FQI +I +++ LG++ A + R+GQ +G+ D     R +   +L  + I  +F  + + F RQ I  +F++D ++   +++LL  +  + F + F  I   IL  C RQS+GA  + + YY  G PI  +L Y    GI G W+G+ +   +  +   +    T+W     ++ +N+ +  L    +++IN  
Sbjct:   72 IINIFGLSIDTGFSSACDTLFSQAYGSRNRKLMGTLLQRALCVVCLMYMTLVCIHLNIETVLLLLGQNPLIASLTSEYIAYFLPGLGFDFLFLTFARYLQSQNIIQPMVYSTFTGTVFNILAQYYFVVRLNYGLRASAVCLSLSFGCMFLCELGYILASKVYKETWNGFNLNSAFSNWGIFFKLGIPGVLMVGLEEWCFEIMTIMAGTLGSVTLGAQAIVFQIQSIIYMVPLGLFTAVNIRVGQKLGAFDPVG-ARYVYTTALTIISIVALFTGLPVVFLRQYIPYMFTSDEKVCLLASRLLPMLLLFQFFEGFAGISEAILLACGRQSIGAITIFLGYYCTGMPIAALLTYQTSLGILGSWIGLTIGFGLTTMVYTILALRTDWTEQVRRARNNVTE-TLSVYSTNNINEQ 481
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Cavefish
Match: slc47a2.1 (solute carrier family 47 member 1 [Source:NCBI gene;Acc:103046628])

HSP 1 Score: 223.787 bits (569), Expect = 3.888e-63
Identity = 118/397 (29.72%), Postives = 216/397 (54.41%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFH-----LNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSE 2063
            +IN+ G SI  G +++ +TL +Q FGS   K++G+ILQR V+++      LACF      +N EPIL++++Q   +A L+  Y+ +Y+P L   F + +  RYLQNQ I++P  ++   G ++N ++ Y+ +H+   G   +A   +IS   +      YI    ++  TW+G+S  +  ++W     L  P + ++ +E W +E G  +AG +   +LGAQS+ ++++TI+++  LG  +A S R+G  +G+ +    K   KV  + G+L+ C    +    +  I   F+ + EI    ++++    F+   D   AI  GI+ G  +Q VGA   I+ +Y +GFPIG  L++    GI G+W G  V +F++++   + +   +W     +++
Sbjct:   95 VINVTGLSIGSGLASACDTLISQTFGSNNLKRVGVILQRGVLIL-----LLACFPCWAILINTEPILLAVRQSPRVASLSQLYVKIYMPSLPAAFMYQLQGRYLQNQGIIWPQVITGAAGNILNALINYIFLHLLHLGVAGSAAANSISQCSLAVFLYVYIRWKGLHKATWDGWSR-DCLQEWGAFIRLAFPSMLMLCVEWWTYEIGGFLAGLIGETELGAQSVIYELATIAYMFPLGFAVAASVRVGNALGAGNTEQAKLSGKVALICGLLVSCGVAALISGLKDVIAYTFTTEQEIIVRVSEVMAMYGFFHLFDATAAITGGIVRGAGKQLVGAMCNIVGFYFVGFPIGVSLMFALSMGIVGLWAGFFVCVFLQSVFFLILICKLDWKKATKEAQ 485
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Cavefish
Match: slc47a3 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:103046114])

HSP 1 Score: 213.001 bits (541), Expect = 1.242e-59
Identity = 116/415 (27.95%), Postives = 224/415 (53.98%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFH-----LNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINS 2117
            I+N+   ++  G +++ +TL +Q FGS   +++G+I+QR +I++      LACF      +N E IL+ +KQ+  +A L+  Y+ +++P L   F F+I S YLQNQ I++P+ ++  I  V+N +  Y+ + V   G   +A    +S ++M      YI    ++ DTW G+S+    ++W   F L +PG+ ++  E W +E G  +AG +S ++LGAQSI ++++ ++++  +G  +A   R+G  +G+ D    K   K+     V +      +    +  I  +FSND +I+     +++  + +  LD   A    I+ G  +Q +GA   +  YY +GFPIG  L++  + GI G+W G+++ +F +++     +   NW+    +++     + ++E   DD+++
Sbjct:   73 ILNVSSVAVGYGLASACDTLISQTFGSGNLQRVGVIVQRGLIIL-----LLACFPCWAILINTESILLLVKQNPDVAKLSQMYVKIFMPALPALFVFIIESTYLQNQGIIWPLVITGAIANVLNALSNYVFLFVLDLGVPGSAAANTVSQYLMAIVLFIYIRCRGLHKDTWYGWSM-ECLQEWDTFFHLAIPGLLMLCAEWWTYELGAFLAGLISPVELGAQSIIYELANVAYMFPIGFSVAGCVRVGNAMGAGDTAQAKLSAKLAMACAVSVAVCLAIIVGFTKDVISYIFSNDEQIRARVATVMVLYAPFHLLDATAAAAGSIVRGLGKQKLGAVGNVFGYYAVGFPIGVSLMFAAKMGIFGLWTGLLICVFFQSVFFITLLSKLNWEKATEEAQIR-AGVHMNE--KDDVDA 478
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Cavefish
Match: slc47a3 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:103046114])

HSP 1 Score: 211.46 bits (537), Expect = 8.012e-59
Identity = 116/402 (28.86%), Postives = 218/402 (54.23%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFH-----LNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSF-----RQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSE 2063
            I+N+   ++  G +++ +TL +Q FGS   +++G+I+QR +I++      LACF      +N E IL+ +KQ+  +A L+  Y+ +++P L   F F+I S YLQNQ I++P+ ++  I  V+N +  Y+ + V   G   +A    +S ++M      YI    ++ DTW G+S+    ++W   F L +PG+ ++  E W +E G  +AG +S ++LGAQSI ++++ ++++  +G  +A   R+G  +G+ D    K   K+      + C V   V L+      +  I  +FSND +I+     +++  + +  LD   A    I+ G  +Q +GA   +  YY +GFPIG  L++  + GI G+W G+++ +F +++     +   NW+    +++
Sbjct:   73 ILNVSSVAVGYGLASACDTLISQTFGSGNLQRVGVIVQRGLIIL-----LLACFPCWAILINTESILLLVKQNPDVAKLSQMYVKIFMPALPALFVFIIESTYLQNQGIIWPLVITGAIANVLNALSNYVFLFVLDLGVPGSAAANTVSQYLMAIVLFIYIRCRGLHKDTWYGWSM-ECLQEWDTFFHLAIPGLLMLCAEWWTYELGAFLAGLISPVELGAQSIIYELANVAYMFPIGFSVAGCVRVGNAMGAGDTAQAKLSAKL-----AMACAVSVAVCLAIIVGFTKDVISYIFSNDEQIRARVATVMVLYAPFHLLDATAAAAGSIVRGLGKQKLGAVGNVFGYYAVGFPIGVSLMFAAKMGIFGLWTGLLICVFFQSVFFITLLSKLNWEKATEEAQ 463
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Cavefish
Match: ENSAMXT00000033072.1 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:103022207])

HSP 1 Score: 195.667 bits (496), Expect = 6.042e-53
Identity = 117/416 (28.12%), Postives = 208/416 (50.00%), Query Frame = 3 
Query:  921 GFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQS-----ESNIEKIQLD-------ETISDDINSDNSKN 2132
            G + + +TL +Q FGS+    +G+ILQR V+++ L  +      +N +P+L+ L QD  +A +   Y+I+YLP +   F   +   YLQNQ ++ P   ++    + N++  Y+ I    FG   +AV  A++   +      YI   +++ +TW G+SL  S +DW     L +P   ++  E W +E G  +AG LS + L AQ     ++T +++ +LG+  AT  R+G  +G+ D        KV      L+  V   V    +  I  LF++D  I +  + +L    F  F D    +  GIL G  +Q + A A +I YY IG P+G  L++  +  + G W+G+++ + +++    + ++  NW+ V  ++     +SN+ + QLD         +  +  S NS+N
Sbjct:   94 GLALACDTLVSQTFGSKNLLHVGVILQRGVLILLLFCLPCWALLINTQPLLLLLGQDPEVARIAQLYVIVYLPAVPASFLHQLQVAYLQNQGVILPQVYTAIAANIANVLTNYILITWLDFGVYGSAVANAVAEIYICVFLYAYIRWKRLHCETWGGWSL-ESLQDWGAYMKLAIPSTMMLCFEWWIYEIGGFLAGMLSEMDLAAQHAVLMLATTNYMFNLGMQGATCVRVGNALGAGDTTGAVLTCKVSLTLTALLAVVQGAVLAGLKPVIGFLFTDDRVIVQMVSDILTVYCFLEFFDGLVCVCMGILLGSGQQKIAAVANLIGYYCIGLPLGISLMFAAKLEVVGFWLGLLICVCIQSTFFIVVIFRLNWERVTKEAIERSGKSNLNRRQLDFEGEPSQSIVPANYTSQNSEN 508
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Cavefish
Match: slc47a4 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:103046413])

HSP 1 Score: 182.185 bits (461), Expect = 2.427e-48
Identity = 128/497 (25.75%), Postives = 234/497 (47.08%), Query Frame = 3 
Query:  891 INIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVC----QAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFS---GILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDET-ISDDINSD------------NSKN------LSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNM 2303
            IN+   +   G + + +TL +Q FGS+    +G+ILQR V+++ L  +      +N +P+L+ + QD  +A +   Y++ Y+P +   F + +   YLQNQ ++ P   +S +  +VN +  Y+ +  +  G   +A      Q  S F +F     YI I K+++ TW G+S   S +DW     L +P   +   E W +E G  +AG L  + L AQ +   ++ I+++I LG+  A   R+G  +G+ +        KV  +   ++  +   V  S +  I  +F++D  I E  ++L+     Y  L  F  I     GIL G  +Q + A A ++ YY+IG P+  IL +  +  + G W+G++VA+F+ A+   + ++  NW      +E  I++  + +T I  D  S             N +N      +S+   T ER              P   E + +  +E + +A+ K++  Q  + + +
Sbjct:   84 INVTTAATGFGLALACDTLVSQTFGSKNLLHVGVILQRGVLILLLFCLPCWALLINTQPLLLLVGQDPEVARIAQIYVVAYIPAVPAMFLYQLQLSYLQNQGVIIPQMYASVVANIVNALANYVLLFWWDLGVHGSAAANSFAQVFSCFALFT----YIRIKKLHVKTWGGWSS-ESLQDWGAYMKLAIPSTLMACFEWWIYEVGGFLAGMLGEVDLAAQHVVIMLAYINYMIPLGLQGAACVRVGNALGAGNTAGAIHTSKVSLILAAILAILQGIVLASTKTVIAFIFTSDESIAELVSELM---GIYCPLQFFNGILCVGMGILLGTGQQKIAAIANLLGYYLIGLPLSIILTFPAKLQVAGFWLGLLVAVFLLAIYFIVIIFRLNWK---KMTEEAIKRAGMGKTVIHSDFRSSHRLSDSFFLAVTNGENGNVYQIVSSRDQTEER------------SPPVAQERQGVRQEEEKSSAAPKLSTSQLMIRRGL 557
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Yeast
Match: YDR338C_mRNA (Putative protein of unknown function; member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily [Source:SGD;Acc:S000002746])

HSP 1 Score: 132.494 bits (332), Expect = 2.065e-32
Identity = 109/422 (25.83%), Postives = 199/422 (47.16%), Query Frame = 3 
Query:  921 GFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYI---ILYLPGLFFDFQFMIISRYLQNQNI----VYPMTVSSFIGTVVNLIL---QYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMD---TWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQS----ESNIEKIQLDETISDDINSDNSKNL 2135
            G +TS +TL  Q +GS +   +G+ LQR +    +IY+  A      EP+L  +  +  +  LT++++   IL  P   F   F  + R+LQ Q I    +Y +T+ + +  +V+  L   +Y+ +     GF  AA    I+  + F      +L   +Y+D    W GFS   +F  W  +  L   GI ++  EE  +E  T+ +    +  L AQS    ++ + ++I   I ++TSTRI  ++G+K         +V   F  +   + C + +  R  I  ++S DPE+ +   ++L  +      D   A+    L G   QS+G+   ++ YY+ G P+  IL + F   + G+W+GI  A+ +  L    +V + +WD +   +    E+  +++  DE ++D  + D +  L
Sbjct:  284 GIATSLDTLCPQAYGSGRFYSVGVHLQRCIAFSLVIYIPFAVMWWYSEPLLSYIIPEKELINLTSRFLRVLILGAPAYIF---FENLKRFLQAQGIFDAGIYVLTICAPLNVLVSYTLVWNKYIGV-----GFIGAA----IAVVLNFWLMFFLLLFYALYIDGRKCWGGFSR-KAFTHWNDLGHLAFSGIIMLEAEELSYELLTLFSAYYGVSYLAAQSAVSTMAALLYMIPFAIGISTSTRIANFIGAKRTDFAHISSQVGLSFSFIAGFINCCILVFGRNLIANIYSKDPEVIKLIAQVLPLVGIVQNFDSLNAVAGSCLRGQGMQSLGSIVNLMAYYLFGIPLALILSWFFDMKLYGLWIGIGSAMLLIGLVEAYYVLFPDWDKIMTYAEILKETEDDEVDSDEYLTDSDDPDENTAL 692
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Yeast
Match: ERC1 (Member of the multi-drug and toxin extrusion (MATE) family; the MATE family is part of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily; overproduction confers ethionine resistance and accumulation of S-adenosylmethionine [Source:SGD;Acc:S000001074])

HSP 1 Score: 110.538 bits (275), Expect = 1.220e-25
Identity = 86/332 (25.90%), Postives = 158/332 (47.59%), Query Frame = 3 
Query:  894 NIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYM-FLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAI--HVYQFGFQSAAVCQAISSFVMFACELGYILISKVY---MDTWNGF-SLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQ 1868
            NI G +   G  T  +TL AQ +G++    +G+++QR  ++  L ++  +  + +  E IL  +  +  +  L A Y+ +   G+     F    R+LQ Q I +  T+  F+   +N ++ YL +       G+  A +   I+ ++M    L Y + +K     +  WNG      +F++W+ +  L +PG+ +V  E  GFE  T+ A  L    LGAQSI   I+++++ +   I ++TSTR+  ++G+    S     +V  L   +   +   V   ++++I  LFS +  + +     L  ++F    D F A  +G L G  RQ
Sbjct:  212 NITGLAAIQGLCTCLDTLCAQAYGAKNYHLVGVLVQRCAVITILAFLPMMYVWFVWSEKILALMIPERELCALAANYLRVTAFGVPGFILFECGKRFLQCQGIFHASTIVLFVCAPLNALMNYLLVWNDKIGIGYLGAPLSVVINYWLMTLGLLIYAMTTKHKERPLKCWNGIIPKEQAFKNWRKMINLAIPGVVMVEAEFLGFEVLTIFASHLGTDALGAQSIVATIASLAYQVPFSISVSTSTRVANFIGASLYDSCMITCRVSLLLSFVCSSMNMFVICRYKEQIASLFSTESAVVKMVVDTLPLLAFMQLFDAFNASTAGCLRGQGRQ 543
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Nematostella
Match: EDO46474 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ02])

HSP 1 Score: 158.688 bits (400), Expect = 3.851e-42
Identity = 105/366 (28.69%), Postives = 185/366 (50.55%), Query Frame = 3 
Query:  891 INIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVV---NLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSL----FGVLIC-CVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKG 1964
            IN+ GYS+ +G  T+  TL +Q +G+++   +G  LQR + ++++  +    F +  E  L+ +  +  I+ +T KYI++ LP L   F   ++ RYLQ Q I+ P+    +IG VV    + + YL +     G    A+   ++ ++     L YI I K++  TW G+S  +   DW+    L +PG+ ++ +E W FE G+ + G +    + A  I FQ++TISF++ +G  LA +  +G  +GS      K V KV  +    F  L+  CV C      R+ I   F++D E+   + + L  +  +   D    + +GI+ G  RQ +G    +I Y++I  P+G  L ++    + G
Sbjct:   50 INVTGYSVAVGLCTALETLCSQAYGAKKYGMVGTYLQRGICILSVAMLLTYSFWMQTEHFLLGIGVEQQISRMTDKYIMMSLPILPGIFGQTLLQRYLQVQGIMQPVL---YIGMVVFCCAIGINYLLVLTLHLGISGIAISFYVNYYLFSVLLLVYIYIRKIHHLTWKGWSF-SCLDDWRQFIGLAVPGMMMICVEWWSFEIGSFLLGRIDDSNVAAHGILFQLATISFMLPIGTGLAATVSVGMALGSNQPDRAKLVTKVSLIITIAFSALVAICVVCA-----RKYIVLAFTDDREVINLTIQTLPIVGTFLVFDASQGVMAGIIRGSGRQKIGLVLNVITYFIIALPLGITLTFIAHLDLLG 406
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Medaka
Match: ENSORLT00000002449.2 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101156384])

HSP 1 Score: 241.891 bits (616), Expect = 1.106e-69
Identity = 137/454 (30.18%), Postives = 245/454 (53.96%), Query Frame = 3 
Query:  888 IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFH-----LNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDN--SKNLSTTLDTVERLLKRFWKNKSFIKIPSESETEN 2228
            IIN+ G SI  G S + +TL +Q FGS   K++G+ILQR V+++      LACF      +N EP+L++ KQ+  ++ L+  Y+ +++P L   F + + SRYLQNQ I++P  ++  IG + N I+ Y+ ++    G   +A   AIS F++      YI +  ++  TW+G+SL +  ++W     L +P + ++ LE W FE G  +AG +   +LGA S+A+Q++ I++++ LGI  A S R+G  +G+  +   K   KV  + G ++  +  T+  S +  I  +F++D EI +++  ++  + F  F D    I  GIL G  +Q VGA   ++ YYV G PIG  L++     + G+W G+ + +F+++    ++++  NW     +++     +Q+ +    +I   N     +S T  + +     + K    + IP ES+  N
Sbjct:   96 IINVTGISIGTGLSLTCDTLISQTFGSGNLKRVGVILQRGVLIL-----LLACFPCWAVLINTEPLLLAFKQNPEVSRLSQLYVNIFMPSLPASFMYQLQSRYLQNQGIIWPQVITGAIGNIFNAIINYVLLYPLDLGVAGSAAANAISQFLLAVLLFVYICLKGLHKATWDGWSL-DCLQEWGPFVKLAIPSMLMLCLEWWIFEVGGFLAGMIGEAELGAHSVAYQLAVIAYMLPLGISAAASVRVGNALGAGKVEQAKLSCKVPIICGFIVAFMMGTILGSTKDVIGYIFTSDQEILDKAPGVVFVLGFTHFFDCIAGITGGILRGAGKQMVGALCNLVGYYVFGVPIGVSLMFAAHMNVVGLWTGLTICVFMQSSFFLIYLWKLNWKKAAEEAQVR-AGVQIKDEKEMEITDCNRIHSQVSVTAPSCDGEDHTYEK----VNIPEESKAAN 538
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Medaka
Match: slc47a3 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101163594])

HSP 1 Score: 225.328 bits (573), Expect = 5.156e-64
Identity = 126/432 (29.17%), Postives = 235/432 (54.40%), Query Frame = 3 
Query:  894 NIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFH-----LNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQL-DETISDDINSDNSKNLSTT--LDTVERL 2165
            N+ G SI +G +++ +TL +Q +GS   +K+G+ILQRA++++      LACF      +N  PIL++ +Q+  +A L   Y+ +++P L   F F ++SRYLQNQ I++P  ++ F+  ++N ++ Y+ + V + G   +A+    S F M     GYI+   ++  TW G+S      DW     L +P + ++ +E W +E G  +AG +S ++LGAQSI ++++ ++++  LG  +A + R+G  +G+ +    K   K+      L+      +    +  I  +F+ D +I+E  + ++ + + +  LD   A  SGI+ G  +Q VGA   I+ YY IGFP+G  L++  + GIKG+W G+   + ++ +    ++   NW  V  +++      +   ET  +  +++N +  S T  LD ++ L
Sbjct:   86 NVTGVSIGVGLASACDTLISQTYGSGNLQKVGVILQRAILIL-----LLACFPCWAILINTRPILLAFRQEPEVASLAQLYVKIFMPALPAAFMFSLLSRYLQNQGIIWPQVITGFLVNLLNALINYIFLFVLKMGVAGSALANTFSQFSMAGILFGYIVCRGLHKATWGGWSK-ECLHDWGSYIRLAIPSMVMMCVEWWTYEIGGFLAGLISEVELGAQSIVYELANVAYMFPLGFSVAGNVRVGNALGAGETEQGKLSAKLTLFCAGLVSVGMALLIGGLKDHISYVFTYDEKIRERVSDVISFYAPFLLLDAISAACSGIIRGAGKQRVGAICNIVGYYGIGFPVGVPLMFAAKLGIKGLWTGLFTCVSLQCVFLIFYLIRMNWKDVTIEAQIRAGACETYTETSPEPEDAENYRCPSDTTQLDDIDTL 511
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Medaka
Match: slc47a1 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101170536])

HSP 1 Score: 179.874 bits (455), Expect = 2.511e-47
Identity = 113/389 (29.05%), Postives = 199/389 (51.16%), Query Frame = 3 
Query:  891 INIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHL--NMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQE-ESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYV 2048
            IN+   +   G + + +TL +Q FG +  K++G+ILQR+ ++  L++  L C+ L  N E +L+ +KQ+  +A +   Y++++LP +   F   +   YLQNQ I+ P   ++ +  V NL   YL I V + G   +A+  ++S  V+     GYI   K++  TW G++  N  +DW     L  P   ++ LE W +E G  +AG L    L AQ +  +I ++S++  LGI  A   R+G  +G+ ++       K+  +   ++  V   V    +     +F++D +I E  S  L +YI F  F D    + SGIL G   Q + A   ++ YY IG P+G  L++     I G+W+GI+    ++A    + ++  +W+ +
Sbjct:  107 INVTTTATGYGLAVACDTLISQTFGGKNLKRVGVILQRSSLI--LLFFCLPCWALLINAENLLLLMKQNADVARIAQLYVMMFLPAVPAMFLHHLQVSYLQNQGIILPQMYTAGVANVFNLGANYLLISVLKLGVVGSAIANSLSQIVICLLLFGYIRWRKLHEKTWGGWT-TNCLQDWGSYMKLATPSALMICLEWWVWEIGGFLAGALGEKDLAAQHVLVEIGSLSYMFPLGISAAVCVRVGNALGAGNITRAFVACKLALVLAGVLSVVQGVVIACCKPVAGSIFTSDIDILEIVSNNLTVYI-FLQFFDSILCVSSGILVGSGLQKIAALTNLVSYYCIGLPVGAALMFGAHLRILGLWLGILTCSCIQAAFFLVVIFKIDWNKI 491
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Medaka
Match: slc47a4 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101165411])

HSP 1 Score: 171.014 bits (432), Expect = 1.741e-44
Identity = 115/468 (24.57%), Postives = 213/468 (45.51%), Query Frame = 3 
Query:  891 INIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVN 2294
            +N+   +   G + + +TL +Q FG     ++GIILQR +I++ L  +      +N + +L+ L QD  +A +   YI  YLP +   +   +   YLQNQ I+ P   ++ +  + N+   Y+ I+  Q G   +A    +S   +     GYI   K++  TW G+S + S ++W     L +P   +   E W +E G   AG LS  +L AQ     ++ ++++  LGI  A   R+G  +G+ D        K+          V   V  S +  I  +F++D  I    + L+    F  F D    + +GI  G  +Q + A A +I YY IG P+   L++V +  + G W+G+++ + +++    + ++  NW  +  ++    +K      +  D   DN+ N ++        ++ +        +P  +E  +   +EPE    R + + Q + N
Sbjct:   92 LNVTSAATGFGLALACDTLVSQTFGGRNLLRVGIILQRGIIILLLFCLPCWGLLINAQAVLLCLGQDPVVARIAQLYITAYLPAVPAMYLHHLQVSYLQNQGIIMPQMYAAALANIANVATNYIFIYWLQLGVVGSAAANTLSQVYICVFLFGYIWWKKLHTTTWGGWS-VESLQEWGSYMKLAIPSTLMTCFEWWVYEFGGFFAGMLSEEELAAQHAVIMVAFLTYMFPLGIQAAACARVGNALGAGDTARAILSSKISLALAGCFAIVEGIVLGSTKTVIGFIFTSDERIVGLVSHLINAYCFLQFFDGLVCVCTGIFLGTGKQKIPAVAHLIGYYCIGLPLCVTLMFVAKLRVLGFWIGLLICVILQSTFYIVVIFKLNWKKMTEEAVKRAQKNTRMALVDADALLDNTGNNASQASNNGHSVEGY--------VPVTTENNDGKLEEPE----RHVVLKQRRDN 546
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Medaka
Match: slc47a4 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101165658])

HSP 1 Score: 162.925 bits (411), Expect = 6.378e-42
Identity = 107/416 (25.72%), Postives = 198/416 (47.60%), Query Frame = 3 
Query:  891 INIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLS 2138
            IN+   +   G   + +TL +Q FG +   ++G+ILQR++I++ L  +      +N   IL+ L QD  +A +   YI  +LP +   F   +   YLQNQ I+ P   ++ +G V N++  Y+ I+    G   +A    +S   +      YI   K+++ TW G+S+  S ++W     L +P   +   E W +E G   AG +S  +L AQ     +S I+++   GI  A   R+G  +G+ D        +V       IC V   V  S +  I  +F+ D  I    ++L+    F  F D    + +GI  G  +Q + A A  I YY +G  +   L++  +  I G WVG++V +  ++    + ++  NW+ + +++   +++ Q+   ++  +N+ +  ++ 
Sbjct:   72 INVTTAATGYGLGLACDTLVSQTFGGKNLLRVGVILQRSIIILLLFCLPCWGLLINAHAILLCLGQDPEVARIAQLYITAFLPAVPAMFLHNLQVSYLQNQGIILPQMYTATLGNVANVVTNYILIYWLDLGVGGSAAANTLSQIYICVFLFLYIWWRKIHVKTWGGWSV-ESLQEWGSYMKLAVPSTLMKCFEWWVYEFGGFFAGMMSEDELAAQHAVIMVSFITYMFPFGIQAAACARVGNALGAGDNTGALLTSRVALTLAGSICVVEGLVLGSTKTVIGFIFTADERIIHLVSQLMTAYCFLQFFDGLVCVCTGIFLGAGKQKIPAVANFIGYYCLGLSLSITLMFAAKLRILGFWVGLLVCVIFQSTFYIVVIFRLNWEKIADEA---VKRAQITTCMT--LNAADQSDME 481
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Match: SMESG000005478.1 (SMESG000005478.1)

HSP 1 Score: 935.25 bits (2416), Expect = 0.000e+0
Identity = 487/532 (91.54%), Postives = 493/532 (92.67%), Query Frame = 3 
Query:  879 PHNIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMXXXXXXXXXXVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY 2474
             ++IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSF      + +I I++                     FL  L       LEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY
Sbjct:   25 ANSIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFQGLHGHMEWIFITE---------------------FLQRLER-----LEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY 530
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Match: SMESG000005478.1 (SMESG000005478.1)

HSP 1 Score: 935.25 bits (2416), Expect = 0.000e+0
Identity = 487/532 (91.54%), Postives = 493/532 (92.67%), Query Frame = 3 
Query:  879 PHNIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMXXXXXXXXXXVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY 2474
             ++IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSF      + +I I++                     FL  L       LEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY
Sbjct:   16 ANSIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFQGLHGHMEWIFITE---------------------FLQRLER-----LEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY 521
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Match: SMESG000005478.1 (SMESG000005478.1)

HSP 1 Score: 914.064 bits (2361), Expect = 0.000e+0
Identity = 480/532 (90.23%), Postives = 487/532 (91.54%), Query Frame = 3 
Query:  879 PHNIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMXXXXXXXXXXVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY 2474
             ++IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAA  Q +         + +I I++                     FL  L       LEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY
Sbjct:   25 ANSIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAA--QGLHG------HMEWIFITE---------------------FLQRLER-----LEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY 522
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Match: SMESG000005478.1 (SMESG000005478.1)

HSP 1 Score: 913.294 bits (2359), Expect = 0.000e+0
Identity = 480/532 (90.23%), Postives = 487/532 (91.54%), Query Frame = 3 
Query:  879 PHNIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMXXXXXXXXXXVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY 2474
             ++IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAA  Q +         + +I I++                     FL  L       LEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY
Sbjct:   16 ANSIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAA--QGLHG------HMEWIFITE---------------------FLQRLER-----LEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY 513
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Match: SMESG000005478.1 (SMESG000005478.1)

HSP 1 Score: 905.975 bits (2340), Expect = 0.000e+0
Identity = 476/532 (89.47%), Postives = 484/532 (90.98%), Query Frame = 3 
Query:  879 PHNIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIFLLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMXXXXXXXXXXVITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY 2474
             ++IINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSF      + +I I++                     FL  L       LEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVSNETER   + SA + N   Y
Sbjct:   16 ANSIINIFGYSIDLGFSTSFNTLFAQIFGSEQKKKMGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILYLPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQFGFQSAAVCQAISSFQGLHGHMEWIFITE---------------------FLQRLER-----LEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISLGIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQKICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAYAMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYTNWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWKNKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILLVITMFLFAIIIRVYSTMLWHFPCVIVSNETER-GSITSAIISNEPGY 520
The following BLAST results are available for this feature:
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SLC47A21.761e-6228.54solute carrier family 47 member 2 [Source:HGNC Sym... [more]
SLC47A11.343e-6028.81solute carrier family 47 member 1 [Source:HGNC Sym... [more]
SLC47A11.778e-6028.81solute carrier family 47 member 1 [Source:HGNC Sym... [more]
SLC47A22.475e-5927.17solute carrier family 47 member 2 [Source:HGNC Sym... [more]
SLC47A16.016e-4930.21solute carrier family 47 member 1 [Source:HGNC Sym... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc47a2.11.184e-6830.22solute carrier family 47 member 2.1 [Source:NCBI g... [more]
BX248108.17.084e-6429.80multidrug and toxin extrusion protein 1-like [Sour... [more]
slc47a37.196e-6027.87solute carrier family 47 member 3 [Source:ZFIN;Acc... [more]
slc47a32.350e-5929.35solute carrier family 47 member 3 [Source:ZFIN;Acc... [more]
slc47a41.586e-4826.00solute carrier family 47 member 4 [Source:ZFIN;Acc... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed61.637e-5728.81transmembrane p24 trafficking protein 6 [Source:Xe... [more]
slc47a22.632e-5428.97solute carrier family 47 (multidrug and toxin extr... [more]
ccdc85a7.698e-4331.08coiled-coil domain containing 85A [Source:Xenbase;... [more]
ccdc85a1.581e-4130.29coiled-coil domain containing 85A [Source:Xenbase;... [more]
ENSXETT00000000956.13.298e-1127.21pep primary_assembly:Xenopus_tropicalis_v9.1:2:925... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Slc47a11.440e-5627.56solute carrier family 47, member 1 [Source:MGI Sym... [more]
Slc47a26.571e-5627.89solute carrier family 47, member 2 [Source:MGI Sym... [more]
Slc47a27.616e-5628.03solute carrier family 47, member 2 [Source:MGI Sym... [more]
Slc47a11.298e-2330.17solute carrier family 47, member 1 [Source:MGI Sym... [more]
Slc47a12.576e-1333.33solute carrier family 47, member 1 [Source:MGI Sym... [more]
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BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A1L1P9|S47A1_DANRE8.935e-6830.22Multidrug and toxin extrusion protein 1 OS=Danio r... [more]
sp|Q5RFD2|S47A1_PONAB1.961e-6128.57Multidrug and toxin extrusion protein 1 OS=Pongo a... [more]
sp|Q5R7E4|S47A2_PONAB1.347e-6029.51Multidrug and toxin extrusion protein 2 OS=Pongo a... [more]
sp|A7KAU2|S47A1_RABIT2.385e-6029.54Multidrug and toxin extrusion protein 1 OS=Oryctol... [more]
sp|Q96FL8|S47A1_HUMAN6.452e-6028.81Multidrug and toxin extrusion protein 1 OS=Homo sa... [more]
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BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YKK13.922e-3093.26Multidrug and toxin extrusion protein OS=Schmidtea... [more]
A0A0H3YJN28.093e-12541.20Multidrug and toxin extrusion protein OS=Schmidtea... [more]
A0A0H3YJI21.006e-11237.52Multidrug and toxin extrusion protein (Fragment) O... [more]
G4VIQ32.260e-9941.50Multidrug and toxin extrusion protein OS=Schistoso... [more]
A0A3Q0KMD55.213e-9841.50Multidrug and toxin extrusion protein OS=Schistoso... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc47a2.13.888e-6329.72solute carrier family 47 member 1 [Source:NCBI gen... [more]
slc47a31.242e-5927.95multidrug and toxin extrusion protein 1-like [Sour... [more]
slc47a38.012e-5928.86multidrug and toxin extrusion protein 1-like [Sour... [more]
ENSAMXT00000033072.16.042e-5328.13multidrug and toxin extrusion protein 1-like [Sour... [more]
slc47a42.427e-4825.75multidrug and toxin extrusion protein 1-like [Sour... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
YDR338C_mRNA2.065e-3225.83Putative protein of unknown function; member of th... [more]
ERC11.220e-2525.90Member of the multi-drug and toxin extrusion (MATE... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO464743.851e-4228.69Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000002449.21.106e-6930.18multidrug and toxin extrusion protein 1 [Source:NC... [more]
slc47a35.156e-6429.17multidrug and toxin extrusion protein 1 [Source:NC... [more]
slc47a12.511e-4729.05multidrug and toxin extrusion protein 1 [Source:NC... [more]
slc47a41.741e-4424.57multidrug and toxin extrusion protein 1 [Source:NC... [more]
slc47a46.378e-4225.72multidrug and toxin extrusion protein 1 [Source:NC... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000005478.10.000e+091.54SMESG000005478.1[more]
SMESG000005478.10.000e+091.54SMESG000005478.1[more]
SMESG000005478.10.000e+090.23SMESG000005478.1[more]
SMESG000005478.10.000e+090.23SMESG000005478.1[more]
SMESG000005478.10.000e+089.47SMESG000005478.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023424 ID=SMED30023424|Name=Multidrug and toxin extrusion protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2504bp
AGATTTTAAAGATAATTAACTTCAAATTTCGGGAATGACTGTGTTCAAAC
AAATAAAAAACTTTCAAAGATGCAGTATAAACATAGAGCTAGAGAGGAGA
TGAATTGGTGATTTGGAAAACCAAAAAAAATAACTTCGTGTGAATATTAA
TCAAATTAACGTATCAGGTTAGGCGATTTTCAATTGGTACACATGTCTTT
ACGTTGTTGAATCTATATCTGATAGAAAAATGCTAATCGTGTGACAATTT
GGGAAAGTATATTAGTAATCAATAATCGTATTTTTGTTGGGTTTTGGTTA
TATGATTTATAAAAAAGGAACACGGGGAGTAAAAAATTGACCGACTTGTA
ATTATAATCCATCAATACAAAACTTCTAGAAAAATTCAAAATATTTTATA
ATTGAAATCATGATTTTACTAATCAGCAATTCGTGAGATATCAAAAATTA
TGAGAAATACTTTAAAACCGATATTGTCTTATGAAAACAAATTAAAGCAT
TTTTCATTATTTAAACAAACAATGGCTAAACTCGGGATTTTATTTGATCA
GCATGTTGAACTTATGTTTTCGAGAATTCATGAAAATCGCAAATAAAGTA
CTATTTGTTGAACAAGGTGAAAGTTATTTTTAAGGCCTAATCTTTTTGCT
ATTTTCACAAAAAATTGTTTTAATTTATTGGATGGATAATTTCCCTACTG
TGCTTTCAAATAGTAAAGAAAAATCAAGAACAAAATTAAAATTAATGAAA
ATGTTTCAATCCGTCTGCTGCTTGAATTTTTCATTGAAAGATTTTAAACA
AGAAATTTTCAGTTTGATGTCCATTTTTATTCCAAGTGTTTTGACAACAT
TTTTCAGAATGCTCAACCCGGTGATCAGCCTCATAATATTATCAACATAT
TTGGATATAGCATTGATCTTGGATTTTCAACCTCTTTCAATACCTTATTT
GCACAGATATTTGGGAGTGAACAAAAAAAGAAAATGGGAATTATTTTACA
AAGAGCTGTTATCGTTATGACATTGATATACATGTTTCTCGCATGTTTTC
ATCTCAATATGGAGCCTATTCTAATATCCCTAAAACAGGACATAGGAATA
GCTTATTTGACAGCGAAATATATAATACTTTATTTACCAGGATTATTCTT
TGATTTTCAATTTATGATTATCTCAAGATATCTGCAAAATCAGAATATTG
TCTATCCCATGACCGTTTCTTCTTTTATTGGAACTGTGGTCAATCTGATT
CTGCAGTATTTAGCAATTCATGTCTATCAATTTGGGTTTCAAAGTGCTGC
AGTATGCCAAGCAATATCGTCATTTGTAATGTTTGCTTGTGAATTAGGAT
ACATTCTCATTAGCAAGGTTTACATGGACACATGGAATGGATTTTCATTA
CTGAATTCCTTCAGAGATTGGAAAGTGATATTTTTACTTGGATTACCCGG
AATATTTTTGGTAGGATTAGAAGAGTGGGGTTTTGAAACGGGAACTGTTG
TCGCCGGAACTCTGAGTATTATTCAACTTGGAGCTCAGAGTATTGCCTTT
CAGATTTCAACCATTTCATTTCTTATATCTTTAGGCATTTATCTTGCAAC
AAGTACTCGAATTGGCCAATATGTCGGAAGTAAAGATCTTAGGTCCATTA
AAAGGGTAATAAAAGTTGACAGTTTATTTGGAGTATTAATTTGTTGTGTC
TTTTGTACTGTTACATTAAGCTTTCGACAGAAGATTTGTGAGTTGTTTTC
AAATGATCCCGAAATTCAAGAAGAAAGTACGAAATTACTGATTTACATTT
CGTTTTATCCATTTTTAGATGTTTTTGGTGCGATTTTCTCGGGTATTTTA
TGCGGCTGCGCTCGTCAATCAGTTGGAGCATATGCTATGATCATTTGCTA
TTATGTAATCGGCTTCCCAATCGGTTTCATTTTAGTTTATGTCTTTCAAA
CAGGCATCAAAGGTATGTGGGTTGGGATCATGGTAGCTCTCTTTGTTAAA
GCACTTTCTACTGGATTATTTGTATATTATACCAACTGGGATTATGTCTT
TAATCAGTCAGAGTCAAATATCGAAAAAATTCAGTTAGATGAAACCATTT
CTGATGACATCAATTCAGATAATTCGAAAAACTTAAGTACTACTTTGGAT
ACTGTCGAAAGATTGTTGAAAAGATTTTGGAAAAATAAAAGTTTCATCAA
AATCCCATCGGAGAGTGAAACTGAAAACCTCATTAACGATGAACCGGAAT
TGAATGCATCAAGGAAAATTACCATCTACCAGACCCAAGTTAATAAAAAT
ATGTTAATTAAAAAATTCTTGTTCATTTTATTGGTAATAACTATGTTTTT
ATTTGCTATAATTATCCGTGTTTATTCTACAATGTTATGGCATTTTCCTT
GTGTAATTGTTTCAAATGAGACAGAAAGGTTTTACCAGCTGATCTCAGCT
CGTGTTTGTAACATAAGTTCTTATTAAGTGAGAAATAAATAAAATATATG
TAAA
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protein sequence of SMED30023424-orf-1

>SMED30023424-orf-1 ID=SMED30023424-orf-1|Name=SMED30023424-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=113bp
MDNFPTVLSNSKEKSRTKLKLMKMFQSVCCLNFSLKDFKQEIFSLMSIFI
PSVLTTFFRMLNPVISLIILSTYLDIALILDFQPLSIPYLHRYLGVNKKR
KWELFYKELLSL*
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protein sequence of SMED30023424-orf-2

>SMED30023424-orf-2 ID=SMED30023424-orf-2|Name=SMED30023424-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=498bp
MGIILQRAVIVMTLIYMFLACFHLNMEPILISLKQDIGIAYLTAKYIILY
LPGLFFDFQFMIISRYLQNQNIVYPMTVSSFIGTVVNLILQYLAIHVYQF
GFQSAAVCQAISSFVMFACELGYILISKVYMDTWNGFSLLNSFRDWKVIF
LLGLPGIFLVGLEEWGFETGTVVAGTLSIIQLGAQSIAFQISTISFLISL
GIYLATSTRIGQYVGSKDLRSIKRVIKVDSLFGVLICCVFCTVTLSFRQK
ICELFSNDPEIQEESTKLLIYISFYPFLDVFGAIFSGILCGCARQSVGAY
AMIICYYVIGFPIGFILVYVFQTGIKGMWVGIMVALFVKALSTGLFVYYT
NWDYVFNQSESNIEKIQLDETISDDINSDNSKNLSTTLDTVERLLKRFWK
NKSFIKIPSESETENLINDEPELNASRKITIYQTQVNKNMLIKKFLFILL
VITMFLFAIIIRVYSTMLWHFPCVIVSNETERFYQLISARVCNISSY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0042908xenobiotic transport
GO:0055085transmembrane transport
GO:0006855drug transmembrane transport
Vocabulary: molecular function
TermDefinition
GO:0042910xenobiotic transporter activity
GO:0015297antiporter activity
GO:0015238drug transmembrane transporter activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR002528MATE_fam
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002528Multi antimicrobial extrusion proteinPFAMPF01554MatEcoord: 158..316
e-value: 5.4E-27
score: 94.4
coord: 2..93
e-value: 7.6E-10
score: 38.7
IPR002528Multi antimicrobial extrusion proteinTIGRFAMTIGR00797TIGR00797coord: 3..329
e-value: 5.7E-51
score: 171.6
NoneNo IPR availablePANTHERPTHR11206MULTIDRUG RESISTANCE PROTEINcoord: 2..389
NoneNo IPR availablePANTHERPTHR11206:SF268MULTIDRUG AND TOXIN EXTRUSION PROTEIN-RELATEDcoord: 2..389
NoneNo IPR availablePROSITEPS51257PROKAR_LIPOPROTEINcoord: 1..21
score: 5.0
NoneNo IPR availableCDDcd13132MATE_eukaryoticcoord: 1..353
e-value: 4.69446E-99
score: 303.34
NoneNo IPR availableTMHMMTMhelixcoord: 73..95
NoneNo IPR availableTMHMMTMhelixcoord: 9..31
NoneNo IPR availableTMHMMTMhelixcoord: 182..204
NoneNo IPR availableTMHMMTMhelixcoord: 267..289
NoneNo IPR availableTMHMMTMhelixcoord: 445..464
NoneNo IPR availableTMHMMTMhelixcoord: 46..68
NoneNo IPR availableTMHMMTMhelixcoord: 225..247
NoneNo IPR availableTMHMMTMhelixcoord: 148..167
NoneNo IPR availableTMHMMTMhelixcoord: 328..350
NoneNo IPR availableTMHMMTMhelixcoord: 296..318
NoneNo IPR availableTMHMMTMhelixcoord: 105..127