SMED30023422

Overview
NameSMED30023422
Smed IDSMED30023422
Length (bp)1783
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30023422 (SMED30023422) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30023422 (SMED30023422) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30023422 (SMED30023422) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30023422 (SMED30023422) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023422

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30023422 SmedASXL_005857SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30023422 SmedASXL_005857SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30023422 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.001546:7235..9151 -8744
Homology
[Close]
BLAST of SMED30023422 vs. Ensembl Human
Match: NSUN5 (NOP2/Sun RNA methyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:16385])

HSP 1 Score: 195.667 bits (496), Expect = 2.613e-55
Identity = 150/443 (33.86%), Postives = 224/443 (50.56%), Query Frame = -3 
Query:  324 NLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGC--PLISKMKV-FKTILDELISENKLKTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDRI 1634
            ++K  ++ S+F  ++K+L A+V E  +  A+++ +   + L + E K                 KV +Y++L G+      G    L+ + +   K  L  L     +   E++L        +  LP +VR+N L       +++F   G++   Y+ ++      L+ L+ LK   F+ D  L  ELLVF     LH   L RA  +++QD+ASC+PA +LDP     VIDACAAPGNKT+HL ++L  + K      +FAFD D  R  S+ + L       A           EDF  V P+DPRY  V YI LDPSCSGSG+     R  E          RL +L  FQ   L HAL+FP+++R+VYSTCS+  EENE VV + +++    F+L+P    +W  RG   F   + C+R SP   L +GFFVA  +R+
Sbjct:   20 SIKGLVYSSNFQ-NVKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRPH-----------LAKVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLEVGSRPGPASQLPRFVRVNTLKTCSDDVVDYFKRQGFS---YQGRASS----LDDLRALKGKHFLLD-PLMPELLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKNQGK------IFAFDLDAKRLASMATLL-------ARAGVSCCELAEEDFLAVSPSDPRYHEVHYILLDPSCSGSGM---PSRQLEEPGAGTPSPVRLHALAGFQQRALCHALTFPSLQRLVYSTCSLCQEENEDVVRDALQQNPGAFRLAPALP-AWPHRGLSTFPGAEHCLRASPETTLSSGFFVAVIERV 425
[Close]
BLAST of SMED30023422 vs. Ensembl Human
Match: NSUN5 (NOP2/Sun RNA methyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:16385])

HSP 1 Score: 194.512 bits (493), Expect = 3.138e-55
Identity = 150/443 (33.86%), Postives = 224/443 (50.56%), Query Frame = -3 
Query:  324 NLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGC--PLISKMKV-FKTILDELISENKLKTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDRI 1634
            ++K  ++ S+F  ++K+L A+V E  +  A+++ +   + L + E K                 KV +Y++L G+      G    L+ + +   K  L  L     +   E++L        +  LP +VR+N L       +++F   G++   Y+ ++      L+ L+ LK   F+ D  L  ELLVF     LH   L RA  +++QD+ASC+PA +LDP     VIDACAAPGNKT+HL ++L  + K      +FAFD D  R  S+ + L       A           EDF  V P+DPRY  V YI LDPSCSGSG+     R  E          RL +L  FQ   L HAL+FP+++R+VYSTCS+  EENE VV + +++    F+L+P    +W  RG   F   + C+R SP   L +GFFVA  +R+
Sbjct:   20 SIKGLVYSSNFQ-NVKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRPHLA-----------KVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLEVGSRPGPASQLPRFVRVNTLKTCSDDVVDYFKRQGFS---YQGRASS----LDDLRALKGKHFLLD-PLMPELLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKNQGK------IFAFDLDAKRLASMATLL-------ARAGVSCCELAEEDFLAVSPSDPRYHEVHYILLDPSCSGSGM---PSRQLEEPGAGTPSPVRLHALAGFQQRALCHALTFPSLQRLVYSTCSLCQEENEDVVRDALQQNPGAFRLAPALP-AWPHRGLSTFPGAEHCLRASPETTLSSGFFVAVIERV 425
[Close]
BLAST of SMED30023422 vs. Ensembl Human
Match: NSUN5 (NOP2/Sun RNA methyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:16385])

HSP 1 Score: 195.282 bits (495), Expect = 3.804e-55
Identity = 150/443 (33.86%), Postives = 224/443 (50.56%), Query Frame = -3 
Query:  324 NLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGC--PLISKMKV-FKTILDELISENKLKTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDRI 1634
            ++K  ++ S+F  ++K+L A+V E  +  A+++ +   + L + E K                 KV +Y++L G+      G    L+ + +   K  L  L     +   E++L        +  LP +VR+N L       +++F   G++   Y+ ++      L+ L+ LK   F+ D  L  ELLVF     LH   L RA  +++QD+ASC+PA +LDP     VIDACAAPGNKT+HL ++L  + K      +FAFD D  R  S+ + L       A           EDF  V P+DPRY  V YI LDPSCSGSG+     R  E          RL +L  FQ   L HAL+FP+++R+VYSTCS+  EENE VV + +++    F+L+P    +W  RG   F   + C+R SP   L +GFFVA  +R+
Sbjct:   20 SIKGLVYSSNFQ-NVKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRPH-----------LAKVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLEVGSRPGPASQLPRFVRVNTLKTCSDDVVDYFKRQGFS---YQGRASS----LDDLRALKGKHFLLDP-LMPELLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKNQGK------IFAFDLDAKRLASMATLL-------ARAGVSCCELAEEDFLAVSPSDPRYHEVHYILLDPSCSGSGM---PSRQLEEPGAGTPSPVRLHALAGFQQRALCHALTFPSLQRLVYSTCSLCQEENEDVVRDALQQNPGAFRLAPALP-AWPHRGLSTFPGAEHCLRASPETTLSSGFFVAVIERV 425
[Close]
BLAST of SMED30023422 vs. Ensembl Human
Match: NSUN5 (NOP2/Sun RNA methyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:16385])

HSP 1 Score: 192.971 bits (489), Expect = 5.132e-55
Identity = 136/375 (36.27%), Postives = 194/375 (51.73%), Query Frame = -3 
Query:  324 LISKMKVFKTILDELI-SENKLKTKEEILNHF------------------RPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDRI 1382
            L+ + + +  +LD +I S   L+ ++++  H                   RP   S  LP +VR+N L       +++F   G++   Y+ ++      L+ L+ LK   F+ D  L  ELLVF     LH   L RA  +++QD+ASC+PA +LDP     VIDACAAPGNKT+HL ++L  + K      +FAFD D  R  S+ + L       A           EDF  V P+DPRY  V YI LDPSCSGSG+     R  E          RL +L  FQ   L HAL+FP+++R+VYSTCS+  EENE VV + +++    F+L+P    +W  RG   F   + C+R SP   L +GFFVA  +R+
Sbjct:   39 LVCETQRYSAVLDAVIASAGLLRAEKKLRPHLAKVHRGVSRNEDLLEVGSRPGPAS-QLPRFVRVNTLKTCSDDVVDYFKRQGFS---YQGRASS----LDDLRALKGKHFLLD-PLMPELLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKNQGK------IFAFDLDAKRLASMATLL-------ARAGVSCCELAEEDFLAVSPSDPRYHEVHYILLDPSCSGSGM---PSRQLEEPGAGTPSPVRLHALAGFQQRALCHALTFPSLQRLVYSTCSLCQEENEDVVRDALQQNPGAFRLAPALP-AWPHRGLSTFPGAEHCLRASPETTLSSGFFVAVIERV 387
[Close]
BLAST of SMED30023422 vs. Ensembl Human
Match: NOP2 (NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867])

HSP 1 Score: 56.225 bits (134), Expect = 1.174e-7
Identity = 78/338 (23.08%), Postives = 136/338 (40.24%), Query Frame = -3 
Query:  309 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKR-----VVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTD---SWMTRGK-KLFKQCIRTS----PSYDLCNGFFVACFDRIRDHLP 1283
            E   +  P+ +R N L   ++   +  +N G N           +   +W K                L+V+++S  +       A   ++Q  +S +P   L P     ++D C APG KT+++  ++           + A D +  R KS+   L        +T T+  +     F KV            + LD  CSG+G++ + D   + N     D++ +    + Q  LL  A+   N        +VY TCS+T EENE VV+  ++K     +L P   D      TR + + F   +R++    P     +GFF+A F +  + +P
Sbjct:  298 EANEVPRPVTLRTNTLKTRRRDLAQALINRGVNL----------DPLGKWSKT--------------GLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTG------VILANDANAERLKSVVGNLHRL----GVTNTIISHYDGRQFPKV------VGGFDRVLLDAPCSGTGVISK-DPAVKTNK----DEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKK--RNVRLVPTGLDFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMDGFFIAKFKKFSNSIP 588
[Close]
BLAST of SMED30023422 vs. Ensembl Celegans
Match: nsun-5 (Nop2 (NOP2)/SUN domain family member [Source:UniProtKB/TrEMBL;Acc:Q9NAA8])

HSP 1 Score: 178.333 bits (451), Expect = 1.341e-49
Identity = 141/469 (30.06%), Postives = 233/469 (49.68%), Query Frame = -3 
Query:  321 LYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGCPLISKMKVFKTILDELIS-----ENKLKTKEEILNHFRPED---KSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFN-NSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEK--FGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDRIR 1685
            LY E   +   V A   +++N ++ S + +  K LL +  E++K + + +EI Q  +L     K   R+   G   E   + V +Y+ L G   +  S        +  K+++   I      E+ ++ +   +   +  D   K I +P Y RIN L  T   A++      +  L     ++K   F E + ++K+ +   D H+ E L++F  N    +   +V  R +++QDKASC+PA +L+P     V D CAAPG KT+H  +I+  + K      ++A DR   R  +++  L         ++    ++   DF K D TD +++ V +  +DP CSGSGI++++D +   N+    +++RL  L N QAM+L HAL  P +KR VYSTCSV  EENE VV+E++        + L       W  RG K +   + C+R +P   L NGFFVA F+R++
Sbjct:    6 LYNEVAEIIRCVLAKEKSVRNAVYGSSYKNK-KALLRLSCESLKFRPVFDEILQDKEL-----KSMKRDANIGGSVE--LLYVLMYETLVGSGLTRCS--------QELKSVISRRIQRIKEVEHAMQDEGRGIKAMKEADDGMKKIQIPRYARINTLKWTADEAMKTLETEKWKILG----TLKPENFAEMVTKMKDDEVYVDPHV-ENLIIFAPNIQNFYEYWMVEQRYLILQDKASCLPAFLLNPRPGSQVFDTCAAPGMKTSHAAAIMENQGK------VWAMDRAADRVATMKQLLDA-------SKVAIASSFCGDFLKTDVTDKKFSKVKFAIVDPPCSGSGIVKRMDEITGGNA----EKERLEKLKNLQAMILKHALKLPGLKRAVYSTCSVHEEENEQVVDEVLLDTYVRQNYVLKKNVLPEWTYRGLKTYEVGEHCLRANPKVTLTNGFFVAVFERVK 436
[Close]
BLAST of SMED30023422 vs. Ensembl Celegans
Match: nsun-5 (Nop2 (NOP2)/SUN domain family member [Source:UniProtKB/TrEMBL;Acc:Q9NAA8])

HSP 1 Score: 178.333 bits (451), Expect = 1.341e-49
Identity = 141/469 (30.06%), Postives = 233/469 (49.68%), Query Frame = -3 
Query:  321 LYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGCPLISKMKVFKTILDELIS-----ENKLKTKEEILNHFRPED---KSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFN-NSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEK--FGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDRIR 1685
            LY E   +   V A   +++N ++ S + +  K LL +  E++K + + +EI Q  +L     K   R+   G   E   + V +Y+ L G   +  S        +  K+++   I      E+ ++ +   +   +  D   K I +P Y RIN L  T   A++      +  L     ++K   F E + ++K+ +   D H+ E L++F  N    +   +V  R +++QDKASC+PA +L+P     V D CAAPG KT+H  +I+  + K      ++A DR   R  +++  L         ++    ++   DF K D TD +++ V +  +DP CSGSGI++++D +   N+    +++RL  L N QAM+L HAL  P +KR VYSTCSV  EENE VV+E++        + L       W  RG K +   + C+R +P   L NGFFVA F+R++
Sbjct:    6 LYNEVAEIIRCVLAKEKSVRNAVYGSSYKNK-KALLRLSCESLKFRPVFDEILQDKEL-----KSMKRDANIGGSVE--LLYVLMYETLVGSGLTRCS--------QELKSVISRRIQRIKEVEHAMQDEGRGIKAMKEADDGMKKIQIPRYARINTLKWTADEAMKTLETEKWKILG----TLKPENFAEMVTKMKDDEVYVDPHV-ENLIIFAPNIQNFYEYWMVEQRYLILQDKASCLPAFLLNPRPGSQVFDTCAAPGMKTSHAAAIMENQGK------VWAMDRAADRVATMKQLLDA-------SKVAIASSFCGDFLKTDVTDKKFSKVKFAIVDPPCSGSGIVKRMDEITGGNA----EKERLEKLKNLQAMILKHALKLPGLKRAVYSTCSVHEEENEQVVDEVLLDTYVRQNYVLKKNVLPEWTYRGLKTYEVGEHCLRANPKVTLTNGFFVAVFERVK 436
[Close]
BLAST of SMED30023422 vs. Ensembl Celegans
Match: nsun-5 (Nop2 (NOP2)/SUN domain family member [Source:UniProtKB/TrEMBL;Acc:Q9NAA8])

HSP 1 Score: 167.162 bits (422), Expect = 4.125e-46
Identity = 112/325 (34.46%), Postives = 174/325 (53.54%), Query Frame = -3 
Query:  321 KSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFN-NSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEK--FGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDRIR 1277
            K I +P Y RIN L  T   A++      +  L     ++K   F E + ++K+ +   D H+ E L++F  N    +   +V  R +++QDKASC+PA +L+P     V D CAAPG KT+H  +I+  + K      ++A DR   R  +++  L         ++    ++   DF K D TD +++ V +  +DP CSGSGI++++D +   N+    +++RL  L N QAM+L HAL  P +KR VYSTCSV  EENE VV+E++        + L       W  RG K +   + C+R +P   L NGFFVA F+R++
Sbjct:   70 KKIQIPRYARINTLKWTADEAMKTLETEKWKILG----TLKPENFAEMVTKMKDDEVYVDPHV-ENLIIFAPNIQNFYEYWMVEQRYLILQDKASCLPAFLLNPRPGSQVFDTCAAPGMKTSHAAAIMENQGK------VWAMDRAADRVATMKQLLDA-------SKVAIASSFCGDFLKTDVTDKKFSKVKFAIVDPPCSGSGIVKRMDEITGGNA----EKERLEKLKNLQAMILKHALKLPGLKRAVYSTCSVHEEENEQVVDEVLLDTYVRQNYVLKKNVLPEWTYRGLKTYEVGEHCLRANPKVTLTNGFFVAVFERVK 372
[Close]
BLAST of SMED30023422 vs. Ensembl Celegans
Match: nsun-5 (Nop2 (NOP2)/SUN domain family member [Source:UniProtKB/TrEMBL;Acc:Q9NAA8])

HSP 1 Score: 155.221 bits (391), Expect = 8.869e-43
Identity = 98/286 (34.27%), Postives = 156/286 (54.55%), Query Frame = -3 
Query:  321 SVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEK--FGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDRIR 1163
            ++K   F E + ++K+ +   D H+   ++   N    +   +V  R +++QDKASC+PA +L+P     V D CAAPG KT+H  +I+  + K      ++A DR   R  +++  L         ++    ++   DF K D TD +++ V +  +DP CSGSGI++++D +   N+    +++RL  L N QAM+L HAL  P +KR VYSTCSV  EENE VV+E++        + L       W  RG K +   + C+R +P   L NGFFVA F+R++
Sbjct:   14 TLKPENFAEMVTKMKDDEVYVDPHVENLIIFAPNIQNFYEYWMVEQRYLILQDKASCLPAFLLNPRPGSQVFDTCAAPGMKTSHAAAIMENQGK------VWAMDRAADRVATMKQLLDA-------SKVAIASSFCGDFLKTDVTDKKFSKVKFAIVDPPCSGSGIVKRMDEITGGNA----EKERLEKLKNLQAMILKHALKLPGLKRAVYSTCSVHEEENEQVVDEVLLDTYVRQNYVLKKNVLPEWTYRGLKTYEVGEHCLRANPKVTLTNGFFVAVFERVK 282
[Close]
BLAST of SMED30023422 vs. Ensembl Celegans
Match: nol-2 (NucleOLar protein [Source:UniProtKB/TrEMBL;Acc:A0A0M7RDQ9])

HSP 1 Score: 71.2478 bits (173), Expect = 1.053e-12
Identity = 63/255 (24.71%), Postives = 103/255 (40.39%), Query Frame = -3 
Query:  513 PIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHAL-----SFPNVKRVVYSTCS 1262
            P+ +R N L + ++   ++ +N G N     D          W K                L+V+++   +       A   +IQ   S +P   L P     V+D C+APG KT+H+ +++           LFA D +  R +++   L        +  TV  N   E+F+K+ P          I LD  CSG+G++       +++     D Q +   H  Q  L+  AL     + PN   +VYSTCS
Sbjct:  230 PVTIRANSLKVKRRDLAKNLINRGMNVDPAAD----------WTKV--------------GLVVYDSQVPVGATPEYLAGHYMIQGLNSLLPVMALAPQPGDRVLDMCSAPGGKTSHIAALMKNSG------VLFANDANFTRCRAIIGNLHRL----GVNNTVVCNLGGEEFSKIRPN-----GFDRILLDAPCSGTGVI-----WKDQSVKTSKDSQDVQRRHTMQRQLILSALDSLDANSPNGGYLVYSTCS 440
[Close]
BLAST of SMED30023422 vs. Ensembl Fly
Match: Nsun5 (gene:FBgn0259704 transcript:FBtr0299957)

HSP 1 Score: 132.109 bits (331), Expect = 5.222e-33
Identity = 112/390 (28.72%), Postives = 186/390 (47.69%), Query Frame = -3 
Query:  318 KVQIYDMLFGQATSNTSGCPLISKMKVFKTILDELISENKLKTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVF----NNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTV---TVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHAL-SFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQL---SPIWTDSWMTRGKKLF----KQCIRTSPSYDLCNGFFVACFDRIRD 1442
            K+ + ++LFG+   N    P +  ++ +K  L   I +  ++ KE       P       P YVRIN  L +   A+++   + +   +       Y  FL  +K L E +FM D H+ E +L+F    +N  V H   LV +++ ++Q+KA+C+ A +L P +   V+D CAAPG KT H+ +++  K        +++ ++D +R+ +L            IT+      V   L D   + P   R+ +V YI +DPSCSGSG+  ++    E   +     +RL  L   Q  +LSHA+ +FPNVKR+ Y TCS   +E    V +   +    F+L        + W   G K +    K  +   P  DL +G F+A F++ R+
Sbjct:   82 KILVTELLFGRKELNGESKP-VQTVRSYKDRLLNSIRDFGVQRKE-------PN------PRYVRINTNLYSLAEALDYLHKSDWRRKELP-ADASYADFLTAIKSLAENEFMTDLHV-EGVLIFPAKWSNYWVRHP--LVHSKRFILQNKATCLAAELLAPPSGATVLDMCAAPGMKTVHICNVMQNKG------CIYSVEQDHVRYNTL----------CEITKDAGCDIVKPILGDALNLTPE--RFPDVEYILVDPSCSGSGMQNRMTVCDEPKED-----KRLQKLQGLQIKILSHAMGAFPNVKRIAYCTCS-LWKEENEQVVQRCLQLNPSFKLLSCKKALRNKWHNVGDKDYPNIGKNVLYCQPDSDLTDGIFLALFEKRRE 429
[Close]
BLAST of SMED30023422 vs. Ensembl Fly
Match: CG8545 (gene:FBgn0033741 transcript:FBtr0087934)

HSP 1 Score: 65.855 bits (159), Expect = 7.798e-11
Identity = 66/264 (25.00%), Postives = 108/264 (40.91%), Query Frame = -3 
Query:  513 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGY--ICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKR-----VVYSTCS 1283
            E   I  P+ +R N L   ++      +N G N           +   +W K                L+VFN+   L       A   +IQ  +S +P   L P  +  ++D C+APG K +H+ SI+           LFA D +  R K++   ++ +     +   V+     ED TK      R    G+  + LD  C+G+G++ +   +  + + + VD QR    +N Q  LL  A+   + K      +VYSTCS
Sbjct:  353 EASEIARPLTIRTNTLKTRRRDLAGALINRGVNL----------DPLGKWTKV--------------GLVVFNSQVPLGATPEYLAGHYMIQGASSLLPVMALAPQENERILDMCSAPGGKGSHIASIMKNTG------VLFANDSNRDRIKAI---VANFHRLGIVNAVVSC----EDGTKF-----RNIMTGFDRVLLDAPCTGTGVVSKDPSV--KTTKSEVDVQR---CYNLQRKLLLTAIDCTDAKSSTGGYIVYSTCS 569
[Close]
BLAST of SMED30023422 vs. Ensembl Fly
Match: CG11109 (gene:FBgn0037200 transcript:FBtr0078553)

HSP 1 Score: 61.2326 bits (147), Expect = 1.094e-9
Identity = 73/245 (29.80%), Postives = 107/245 (43.67%), Query Frame = -3 
Query:  324 LIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRS--PHAITQTVTVNTQLEDFTKVDPTDPRYANVGY--ICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRV-VYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKL--FKQC-----IRTSPSYDLCN--GFFVACFDRI 1016
            L+Q+  S +   VLDP     ++D CAAPGNKT+H+  ++  +       S+ A D    R +S+   L  Y+S   H    T  V          + T P +    +  I LD  CSG G   Q+       S +    + L+S  + Q  L   A+       + VYSTC+VT +E E +V   + KF  E +L+   T  W   G  L  F+ C      R  PS    +  GFF+A F +I
Sbjct:  129 LLQNLPSIVCVRVLDPQPGERILDMCAAPGNKTSHIAELMGDRG------SVVALDNSASRVRSMLPKLGHYKSITAHVFNSTEAVAADAPSAPVGEFTGPPFPCESFDRILLDAPCSGLGNRPQL-------SCSIKQVKVLSSYPHIQRRLFEQAVQLVRPGGILVYSTCTVTEDECECLVAWALRKF-VELRLTDA-TPRWGGPGLPLPGFEACKSRLLQRFGPSGANADTVGFFIAKFQKI 358
[Close]
BLAST of SMED30023422 vs. Ensembl Fly
Match: CG11109 (gene:FBgn0037200 transcript:FBtr0078552)

HSP 1 Score: 61.2326 bits (147), Expect = 1.211e-9
Identity = 73/245 (29.80%), Postives = 107/245 (43.67%), Query Frame = -3 
Query:  324 LIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRS--PHAITQTVTVNTQLEDFTKVDPTDPRYANVGY--ICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRV-VYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKL--FKQC-----IRTSPSYDLCN--GFFVACFDRI 1016
            L+Q+  S +   VLDP     ++D CAAPGNKT+H+  ++  +       S+ A D    R +S+   L  Y+S   H    T  V          + T P +    +  I LD  CSG G   Q+       S +    + L+S  + Q  L   A+       + VYSTC+VT +E E +V   + KF  E +L+   T  W   G  L  F+ C      R  PS    +  GFF+A F +I
Sbjct:  210 LLQNLPSIVCVRVLDPQPGERILDMCAAPGNKTSHIAELMGDRG------SVVALDNSASRVRSMLPKLGHYKSITAHVFNSTEAVAADAPSAPVGEFTGPPFPCESFDRILLDAPCSGLGNRPQL-------SCSIKQVKVLSSYPHIQRRLFEQAVQLVRPGGILVYSTCTVTEDECECLVAWALRKF-VELRLTDA-TPRWGGPGLPLPGFEACKSRLLQRFGPSGANADTVGFFIAKFQKI 439
[Close]
BLAST of SMED30023422 vs. Ensembl Zebrafish
Match: nsun5 (NOP2/Sun RNA methyltransferase 5 [Source:ZFIN;Acc:ZDB-GENE-040426-2476])

HSP 1 Score: 196.052 bits (497), Expect = 6.746e-56
Identity = 162/479 (33.82%), Postives = 240/479 (50.10%), Query Frame = -3 
Query:  276 INLYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRI---KVQIYDMLFGQATSNTSGCPLISKMKVFKTILDELISENKLKTK----EEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFKQCIRTSPSYDLCNGFFVACFDRIRDHLPSDNKPKPKLHT 1691
            + LY +A  +  KV      +K  ++ S F  ++K+L A+V E  K  +++ EI   +KL K E+K               RI   KV +YD+L G       G    + M   +  L   ++  K+K K    +++L     + ++  +P YVR+N L  + +  I++    G+++     +       LE L  L    F+ D HL ++LLVF+     H   L +A  +++Q KASC+PA +L+P     VIDACAAPGNKT+HL +I+  K K      LFAFD D  R     S +ST      +T     N   +DF KVDP +  Y  V YI LDPSCSGSG++   D + E   +      RL +L  FQ   L+HAL FP ++R+VYSTCS+  +ENE VV   +++    F+L  +  D W  RG +   QC+R S +    +GFFVA  +R      SD +  P  HT
Sbjct:    1 MALYLKAAEILEKVEQKRGAVKTLVYDSKFP-NIKQLFALVCETQKYSSVLQEIINSTKLLK-ETK--------------LRIHLAKVLVYDLLIGHGVK--CGGAWKTTMLKHRARLQAALARIKIKRKVSRNQDLLPSSIQQTQNDVIPRYVRVNTLKTSLEDVIDYLKREGFSYQGTPGR-------LEDLDRLSGKMFLCDLHL-KDLLVFSGKTDFHDHFLYKAGHIILQGKASCLPAFLLNPPVGSHVIDACAAPGNKTSHLAAIMKNKGK------LFAFDLDAKRL----STMSTLLLRAGVTCHKLAN---QDFLKVDPQNSEYKEVKYILLDPSCSGSGMVCLRDELPETQEDG-----RLQALAAFQLHCLNHALQFPQLERIVYSTCSIHSQENEEVVTACLQR-NPGFRLVHLLPD-WPERGHEPLTQCLRASTAKTRTHGFFVAMLERRPAQ--SDKETPPCQHT 431
[Close]
BLAST of SMED30023422 vs. Ensembl Zebrafish
Match: nsun5 (NOP2/Sun RNA methyltransferase 5 [Source:ZFIN;Acc:ZDB-GENE-040426-2476])

HSP 1 Score: 179.489 bits (454), Expect = 8.145e-51
Identity = 126/330 (38.18%), Postives = 176/330 (53.33%), Query Frame = -3 
Query:  276 LPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFKQCIRTSPSYDLCNGFFVACFDRIRDHLPSDNKPKPKLHT 1265
            +P YVR+N L  + +  I++    G+++     +       LE L  L    F+ D HL ++LLVF+     H   L +A  +++Q KASC+PA +L+P     VIDACAAPGNKT+HL +I+  K K      LFAFD D  R     S +ST      +T     N   +DF KVDP +  Y  V YI LDPSCSGSG++   D + E   +      RL +L  FQ   L+HAL FP ++R+VYSTCS+  +ENE VV   +++    F+L  +  D W  RG +   QC+R S +    +GFFVA  +R      SD +  P  HT
Sbjct:   32 IPRYVRVNTLKTSLEDVIDYLKREGFSYQGTPGR-------LEDLDRLSGKMFLCDLHL-KDLLVFSGKTDFHDHFLYKAGHIILQGKASCLPAFLLNPPVGSHVIDACAAPGNKTSHLAAIMKNKGK------LFAFDLDAKRL----STMSTLLLRAGVTCHKLAN---QDFLKVDPQNSEYKEVKYILLDPSCSGSGMVCLRDELPETQEDG-----RLQALAAFQLHCLNHALQFPQLERIVYSTCSIHSQENEEVVTACLQR-NPGFRLVHLLPD-WPERGHEPLTQCLRASTAKTRTHGFFVAMLERRPAQ--SDKETPPCQHT 331
[Close]
BLAST of SMED30023422 vs. Ensembl Zebrafish
Match: nop2 (NOP2 nucleolar protein homolog (yeast) [Source:ZFIN;Acc:ZDB-GENE-050309-7])

HSP 1 Score: 52.373 bits (124), Expect = 1.308e-6
Identity = 81/339 (23.89%), Postives = 133/339 (39.23%), Query Frame = -3 
Query:  306 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKR-----VVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTD---SWMTRGK-KLFKQCIRTS----PSYDLCNGFFVACFDRIRDHLPS 1283
            E   +  P+ +R N L   ++   +  +N G N           +   +W K                L+++++S  +       A   ++Q  +S +P   L P     V+D  AAPG KTT++  ++           + A D +  R KS+   +        +T  V  N     F KV            + LD  CSG+G++ +    A +   +  D   L S H  Q  L+  A+   N        +VY TCS+  EENE VV+  ++K     +L P   D      TR K K F   ++ S    P     +GFFVA   ++ + +P+
Sbjct:  300 EANEVHRPVTIRTNTLKTRRRDLAQALINRGVNL----------DPLGKWSKV--------------GLVIYDSSVPIGATPEYLAGHYMLQGASSFLPVMALSPQEGESVLDMSAAPGGKTTYMAQLMRNTG------MIVANDANVDRLKSVVGNIHRL----GVTNAVICNYDGRQFPKV------MGGFDRVLLDAPCSGTGVISK--DPAVKTGKDEADI--LRSAH-LQKELILSAIDSVNADSQTGGYLVYCTCSIMVEENEWVVDYALKK--RNVKLVPTGLDFGKEGFTRFKEKRFHPSLKLSRRFYPHSHNMDGFFVAKLKKLSNTIPT 591
[Close]
BLAST of SMED30023422 vs. Ensembl Xenopus
Match: mpp6 (membrane protein, palmitoylated 6 [Source:Xenbase;Acc:XB-GENE-983252])

HSP 1 Score: 194.512 bits (493), Expect = 1.076e-54
Identity = 162/481 (33.68%), Postives = 240/481 (49.90%), Query Frame = -3 
Query:  285 INLYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQA--TSNTSGCPLISKMKVFKTILDELISENKLKTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKEL--KEGD-FMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFKQ---CIRTSPSYDLCNGFFVACFDRIR----DHLPSDNKPKPK 1691
            + +Y+ A  +  K+      +K  ++ S F  ++++L A+V E ++  +++ +I   S+L +   K                 KV +YD+LFG+           ++      +  L  L  + K+ + E+++           LP YVR+N +       I +F   GY +L          + +E L EL  K G  F+ D H+  +LL F     LH D L  A  +++QDKASC+PA +L P     VIDACAAPGNKT+ L ++L  K K      LFAFD D  R     + +ST      +T     N   +DF  V P DP+Y  V +I +DPSCSGSGI  Q+  +A++  + +   +RL +L  FQ   LSHALSFP+V+RVVYSTCS+  +ENE VV +I+E+    F L      SW   G  +F     C+R + S  L NGFFVA F R +     H P  +KP+ K
Sbjct:    1 MAVYQTAAGILEKLQRKEGAVKTLVYDSGFK-NVRQLYALVCETLRYASVLEDIITSSQLLRGTKK-----------LPLSLAKVLVYDLLFGKGLQCGGRWKAVILGHKARLRAELARLKVKKKVSSNEDLVTSLGGGAVGPALPRYVRVNPIKTCLNDVIAYFKRRGYTYLGKA-------RSIEELAELGQKSGKRFLQDLHV-PDLLAFPPGTDLHKDSLYTAGHLILQDKASCLPALLLAPPVGSCVIDACAAPGNKTSQLAAMLQNKGK------LFAFDLDTKRL----ATMSTLLLRAGVTCQELAN---QDFLTVSPEDPKYQKVSHILVDPSCSGSGIPDQMRILADKEESAQ--SERLEALSGFQRRALSHALSFPSVQRVVYSTCSIHQQENEEVVRDILEQH-PHFSLIDALP-SWPMHGLNIFPGSSCCLRATLSDTLTNGFFVAVFQRQKKENESHFP--DKPEEK 442
[Close]
BLAST of SMED30023422 vs. Ensembl Xenopus
Match: dapk3 (death-associated protein kinase 3 [Source:Xenbase;Acc:XB-GENE-969752])

HSP 1 Score: 60.4622 bits (145), Expect = 5.312e-9
Identity = 73/302 (24.17%), Postives = 129/302 (42.72%), Query Frame = -3 
Query:  513 FKTILDELISENKLKTKEEILNHFRPE------DKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPA----AVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERN---------SNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCS 1361
            +KT L   ++ +++K     ++   PE       +S  +P+Y  +N    +     +   N G+   D     V Y  +++  K+ ++    P Y L ++L   N    +H        ++++QDKA  +      A+++ D D+ V   C+  G    H+ S+L+ +N       +F      I+ ++ E AL       A      +    E FT +DP+DPR      I L P  SGSG+   V  +  ++         S   V   +L +L   Q   L+HA++F  V+ +VY TCS
Sbjct:   69 YKTRLSAALARSRIKHAIPSIDFILPEGVRKQEQRSSTVPLYAWVNTAKTSTTEVCDGLKNEGFTKTDSPVDLVGYQYYMD--KQCQDVLVFPQY-LKDKL--SNLELFIH-------YRLVLQDKAHILSVHSVRALMNLDDDIIVAAPCS--GYILAHM-SVLTNQNA----CRIFVCG---IKSEARERALLEL---FADMGCKNIKLLKESFTDLDPSDPRLQKAKVILLLPQSSGSGVSDPVQFVLNQHGDTSLLQDFSQGSVGTDKLNALSKQQVTELTHAMTFNKVQALVYCTCS 345
[Close]
BLAST of SMED30023422 vs. Ensembl Xenopus
Match: dapk3 (death-associated protein kinase 3 [Source:Xenbase;Acc:XB-GENE-969752])

HSP 1 Score: 59.6918 bits (143), Expect = 8.881e-9
Identity = 73/302 (24.17%), Postives = 129/302 (42.72%), Query Frame = -3 
Query:  513 FKTILDELISENKLKTKEEILNHFRPE------DKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPA----AVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERN---------SNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCS 1361
            +KT L   ++ +++K     ++   PE       +S  +P+Y  +N    +     +   N G+   D     V Y  +++  K+ ++    P Y L ++L   N    +H        ++++QDKA  +      A+++ D D+ V   C+  G    H+ S+L+ +N       +F      I+ ++ E AL       A      +    E FT +DP+DPR      I L P  SGSG+   V  +  ++         S   V   +L +L   Q   L+HA++F  V+ +VY TCS
Sbjct:   55 YKTRLSAALARSRIKHAIPSIDFILPEGVRKQEQRSSTVPLYAWVNTAKTSTTEVCDGLKNEGFTKTDSPVDLVGYQYYMD--KQCQDVLVFPQY-LKDKL--SNLELFIH-------YRLVLQDKAHILSVHSVRALMNLDDDIIVAAPCS--GYILAHM-SVLTNQNA----CRIFVCG---IKSEARERALLEL---FADMGCKNIKLLKESFTDLDPSDPRLQKAKVILLLPQSSGSGVSDPVQFVLNQHGDTSLLQDFSQGSVGTDKLNALSKQQVTELTHAMTFNKVQALVYCTCS 331
[Close]
BLAST of SMED30023422 vs. Ensembl Xenopus
Match: dapk3 (death-associated protein kinase 3 [Source:Xenbase;Acc:XB-GENE-969752])

HSP 1 Score: 59.6918 bits (143), Expect = 9.788e-9
Identity = 73/302 (24.17%), Postives = 129/302 (42.72%), Query Frame = -3 
Query:  513 FKTILDELISENKLKTKEEILNHFRPE------DKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPA----AVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERN---------SNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCS 1361
            +KT L   ++ +++K     ++   PE       +S  +P+Y  +N    +     +   N G+   D     V Y  +++  K+ ++    P Y L ++L   N    +H        ++++QDKA  +      A+++ D D+ V   C+  G    H+ S+L+ +N       +F      I+ ++ E AL       A      +    E FT +DP+DPR      I L P  SGSG+   V  +  ++         S   V   +L +L   Q   L+HA++F  V+ +VY TCS
Sbjct:   57 YKTRLSAALARSRIKHAIPSIDFILPEGVRKQEQRSSTVPLYAWVNTAKTSTTEVCDGLKNEGFTKTDSPVDLVGYQYYMD--KQCQDVLVFPQY-LKDKL--SNLELFIH-------YRLVLQDKAHILSVHSVRALMNLDDDIIVAAPCS--GYILAHM-SVLTNQNA----CRIFVCG---IKSEARERALLEL---FADMGCKNIKLLKESFTDLDPSDPRLQKAKVILLLPQSSGSGVSDPVQFVLNQHGDTSLLQDFSQGSVGTDKLNALSKQQVTELTHAMTFNKVQALVYCTCS 333
[Close]
BLAST of SMED30023422 vs. Ensembl Xenopus
Match: ENSXETT00000038204.1 (NOP2 nucleolar protein [Source:NCBI gene;Acc:100490904])

HSP 1 Score: 52.373 bits (124), Expect = 1.799e-6
Identity = 79/340 (23.24%), Postives = 137/340 (40.29%), Query Frame = -3 
Query:  291 IDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKR-----VVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTD---SWMTRGKKL-----FKQCIRTSPSYDLCNGFFVACFDRIRDHLPSDNKPK 1271
            +  PI +R N L   ++   +  +N          +SV  +   +W K                L+++++S  +       A   ++Q  +S +P   L P  +  V+D C APG KT+++  ++           + A D +  R +S+   L        +T  +  N      +KV            + LD  CSG+GI+ + D   + N + + D QR     + Q  L+  A+   + +      +VY TCS+T EENE VV+  ++K     +L P   D       R K+       +Q  R  P     +GFF+A   +  + +P  NK K
Sbjct:  268 VQRPITIRTNTLKTRRRDLAQALIN----------RSVNLDPLGKWSKT--------------GLVIYDSSVPIGATPEYLAGHYMLQGASSLLPVIALAPQENERVLDMCCAPGGKTSYMAQLMKNTG------IVVANDMNADRLRSVVGNLHRL----GVTNCIISNYDGRQISKV------LGGFDRVLLDAPCSGTGIISK-DPAVKTNKSVQ-DVQRCA---HIQKELILSAIDALDAQSQTGGFMVYCTCSITVEENECVVDYALKK--RNVKLVPTGLDFGKEGFVRFKERRFHPSLRQARRFYPHTHNMDGFFIAKLRKFSNTIPKPNKGK 560
[Close]
BLAST of SMED30023422 vs. Ensembl Mouse
Match: Nsun5 (NOL1/NOP2/Sun domain family, member 5 [Source:MGI Symbol;Acc:MGI:2140844])

HSP 1 Score: 189.889 bits (481), Expect = 2.630e-53
Identity = 148/442 (33.48%), Postives = 228/442 (51.58%), Query Frame = -3 
Query:  327 NLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGC--PLISKMKV-FKTILDELISENKLKTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDR 1634
            +LK  ++ S+F  +LK+L A+V E  +  A+++ +   + L + E K                 KV +Y++L G+      G    L+ + +   K  L  L     +   E++L       ++  +P +VR+N L    + AI++F   G++   Y+ ++      LE L+ LK G       L  ELLVF     LH   L RA  +++QDKASC+PA +L P     VIDACAAPGNKT+++ ++L  + K      +FAFD+D  R  ++ + +       A           +DF  V P+D RY+ V YI LDPSCSGSG++    R  E +      ++RL +L  FQ   L HAL FP+++R+VYSTCS+  EENE VV+E ++     F+L+P+   +W  RG   F   + C+R SP   L  GFF+A F+R
Sbjct:   20 SLKGLVYSSNFQ-NLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRPHLA-----------KVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQESSRPGQAYQVPRFVRVNTLKTRPEDAIDYFKRQGFS---YQGRASS----LEDLRALK-GQHFLLDPLLPELLVFPAQTDLHEHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLKNQGK------IFAFDQDAKRLAAMATLV-------ARAGVSCCELAEKDFLTVSPSDQRYSQVQYILLDPSCSGSGML---SRQLEEHGEGTPSKERLQALAGFQQRALCHALRFPSLQRLVYSTCSLCQEENEDVVQEALQHNSGTFRLAPVLP-TWPHRGLSTFPGSEHCLRASPETTLTGGFFIAVFER 424
[Close]
BLAST of SMED30023422 vs. Ensembl Mouse
Match: Nop2 (NOP2 nucleolar protein [Source:MGI Symbol;Acc:MGI:107891])

HSP 1 Score: 56.9954 bits (136), Expect = 5.474e-8
Identity = 82/338 (24.26%), Postives = 136/338 (40.24%), Query Frame = -3 
Query:  309 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKR-----VVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTD---SWMTR-GKKLFKQCIRTS----PSYDLCNGFFVACFDRIRDHLP 1283
            E   +  PI +R N L   ++   +  +N G N           +   +W K                L+V+++S  +       A   ++Q  +S +P   L P     ++D C APG KT+++  ++           + A D +  R KS+   L        +T T+  +     F KV            + LD  CSG+G++ + D   + N + + D QR   L   Q  LL  A+   N        +VY TCS+T EENE VV+  ++K     +L P   D      TR   + F   +R++    P     +GFF+A F +  + +P
Sbjct:  287 EANEVPRPITLRTNTLKTRRRDLAQALINRGVNL----------DPLGKWSKS--------------GLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYIAQLMKNTG------VILANDANADRLKSVVGNLHRL----GVTNTIISHYDGRQFPKV------VGGFDRVLLDAPCSGTGVISK-DPAVKTNKDEK-DIQRCAHL---QKELLLSAIDSVNAASKTGGYLVYCTCSITVEENEWVVDYALKK--RNVRLVPTGLDFGQEGFTRFQARRFHPTLRSTRRFYPHTHNMDGFFIAKFKKFSNSIP 577
[Close]
BLAST of SMED30023422 vs. Ensembl Mouse
Match: Nsun6 (NOL1/NOP2/Sun domain family member 6 [Source:MGI Symbol;Acc:MGI:1921705])

HSP 1 Score: 50.0618 bits (118), Expect = 6.344e-6
Identity = 50/173 (28.90%), Postives = 74/173 (42.77%), Query Frame = -3 
Query:  513 VLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLE--SALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYA-NVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRV-VYSTCS 1019
            + +Q+  S + A VLDP     ++D CAAPG KTTH  +++  K +      + A D+   +   L+  ++L    S  A     T   +L+    ++   P    +   I LD  CSG G   Q   MA   +   V     TS    Q  LL  A+       V VYSTC+
Sbjct:  216 IFLQNLPSTVVAHVLDPQPGEKILDMCAAPGGKTTHTAALMQDKGE------VIALDKILTKVNKLKQNASLLGLHSIRAFCFDATKALKLDTTDGIEGGPPFLPESFDRIILDAPCSGMG---QRPNMACTWTLKEV-----TSYQPLQRKLLHVAVQLLKPGGVLVYSTCT 374
[Close]
BLAST of SMED30023422 vs. Ensembl Mouse
Match: Nsun6 (NOL1/NOP2/Sun domain family member 6 [Source:MGI Symbol;Acc:MGI:1921705])

HSP 1 Score: 50.0618 bits (118), Expect = 6.344e-6
Identity = 50/173 (28.90%), Postives = 74/173 (42.77%), Query Frame = -3 
Query:  513 VLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLE--SALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYA-NVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRV-VYSTCS 1019
            + +Q+  S + A VLDP     ++D CAAPG KTTH  +++  K +      + A D+   +   L+  ++L    S  A     T   +L+    ++   P    +   I LD  CSG G   Q   MA   +   V     TS    Q  LL  A+       V VYSTC+
Sbjct:  216 IFLQNLPSTVVAHVLDPQPGEKILDMCAAPGGKTTHTAALMQDKGE------VIALDKILTKVNKLKQNASLLGLHSIRAFCFDATKALKLDTTDGIEGGPPFLPESFDRIILDAPCSGMG---QRPNMACTWTLKEV-----TSYQPLQRKLLHVAVQLLKPGGVLVYSTCT 374
[Close]
BLAST of SMED30023422 vs. Ensembl Mouse
Match: Nsun6 (NOL1/NOP2/Sun domain family member 6 [Source:MGI Symbol;Acc:MGI:1921705])

HSP 1 Score: 50.0618 bits (118), Expect = 6.344e-6
Identity = 50/173 (28.90%), Postives = 74/173 (42.77%), Query Frame = -3 
Query:  513 VLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLE--SALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYA-NVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRV-VYSTCS 1019
            + +Q+  S + A VLDP     ++D CAAPG KTTH  +++  K +      + A D+   +   L+  ++L    S  A     T   +L+    ++   P    +   I LD  CSG G   Q   MA   +   V     TS    Q  LL  A+       V VYSTC+
Sbjct:  216 IFLQNLPSTVVAHVLDPQPGEKILDMCAAPGGKTTHTAALMQDKGE------VIALDKILTKVNKLKQNASLLGLHSIRAFCFDATKALKLDTTDGIEGGPPFLPESFDRIILDAPCSGMG---QRPNMACTWTLKEV-----TSYQPLQRKLLHVAVQLLKPGGVLVYSTCT 374
[Close]
BLAST of SMED30023422 vs. UniProt/SwissProt
Match: sp|Q96P11|NSUN5_HUMAN (Probable 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2)

HSP 1 Score: 194.512 bits (493), Expect = 1.507e-54
Identity = 150/443 (33.86%), Postives = 224/443 (50.56%), Query Frame = -3 
Query:  324 NLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGC--PLISKMKV-FKTILDELISENKLKTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDRI 1634
            ++K  ++ S+F  ++K+L A+V E  +  A+++ +   + L + E K                 KV +Y++L G+      G    L+ + +   K  L  L     +   E++L        +  LP +VR+N L       +++F   G++   Y+ ++      L+ L+ LK   F+ D  L  ELLVF     LH   L RA  +++QD+ASC+PA +LDP     VIDACAAPGNKT+HL ++L  + K      +FAFD D  R  S+ + L       A           EDF  V P+DPRY  V YI LDPSCSGSG+     R  E          RL +L  FQ   L HAL+FP+++R+VYSTCS+  EENE VV + +++    F+L+P    +W  RG   F   + C+R SP   L +GFFVA  +R+
Sbjct:   20 SIKGLVYSSNFQ-NVKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRPHLA-----------KVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLEVGSRPGPASQLPRFVRVNTLKTCSDDVVDYFKRQGFS---YQGRASS----LDDLRALKGKHFLLD-PLMPELLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKNQGK------IFAFDLDAKRLASMATLL-------ARAGVSCCELAEEDFLAVSPSDPRYHEVHYILLDPSCSGSGM---PSRQLEEPGAGTPSPVRLHALAGFQQRALCHALTFPSLQRLVYSTCSLCQEENEDVVRDALQQNPGAFRLAPALP-AWPHRGLSTFPGAEHCLRASPETTLSSGFFVAVIERV 425
[Close]
BLAST of SMED30023422 vs. UniProt/SwissProt
Match: sp|Q8K4F6|NSUN5_MOUSE (Probable 28S rRNA (cytosine-C(5))-methyltransferase OS=Mus musculus OX=10090 GN=Nsun5 PE=2 SV=2)

HSP 1 Score: 189.889 bits (481), Expect = 1.839e-52
Identity = 148/442 (33.48%), Postives = 228/442 (51.58%), Query Frame = -3 
Query:  327 NLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGC--PLISKMKV-FKTILDELISENKLKTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDR 1634
            +LK  ++ S+F  +LK+L A+V E  +  A+++ +   + L + E K                 KV +Y++L G+      G    L+ + +   K  L  L     +   E++L       ++  +P +VR+N L    + AI++F   G++   Y+ ++      LE L+ LK G       L  ELLVF     LH   L RA  +++QDKASC+PA +L P     VIDACAAPGNKT+++ ++L  + K      +FAFD+D  R  ++ + +       A           +DF  V P+D RY+ V YI LDPSCSGSG++    R  E +      ++RL +L  FQ   L HAL FP+++R+VYSTCS+  EENE VV+E ++     F+L+P+   +W  RG   F   + C+R SP   L  GFF+A F+R
Sbjct:   20 SLKGLVYSSNFQ-NLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRPHLA-----------KVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQESSRPGQAYQVPRFVRVNTLKTRPEDAIDYFKRQGFS---YQGRASS----LEDLRALK-GQHFLLDPLLPELLVFPAQTDLHEHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLKNQGK------IFAFDQDAKRLAAMATLV-------ARAGVSCCELAEKDFLTVSPSDQRYSQVQYILLDPSCSGSGML---SRQLEEHGEGTPSKERLQALAGFQQRALCHALRFPSLQRLVYSTCSLCQEENEDVVQEALQHNSGTFRLAPVLP-TWPHRGLSTFPGSEHCLRASPETTLTGGFFIAVFER 424
[Close]
BLAST of SMED30023422 vs. UniProt/SwissProt
Match: sp|O14039|RCM1_SCHPO (25S rRNA (cytosine-C(5))-methyltransferase rcm1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rcm1 PE=3 SV=3)

HSP 1 Score: 155.992 bits (393), Expect = 3.364e-40
Identity = 150/450 (33.33%), Postives = 216/450 (48.00%), Query Frame = -3 
Query:  339 KNGLFQSHFSS---DLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGCPLISKMKVFKTILDELISENKLKTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDM--DVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWT--------DSWMTRG-------KKLFKQCIRTSPSYDLCNGFFVA 1628
            K  + Q  F+S   D K+  A+V E +K K +++EI  RS+L  +E K            EN   +V ++D+L  +   + S  P+   +   KT L+    + K+K   +       ++  + LP ++RIN +  TK   ++     G       DK       +  ++EL    F  D  + E L+  + S  +  + L +  KV+IQDKASC PAAVL   T    D+ID CAAPGNKTTHL +       P+S I  FAF+RD  R ++L       R    I+    V  + +DFT  DP    Y NV +I LDPSCSGSGI+ + D +     +   D +RL +L +FQ+ +L HAL FPN + V YSTCSV   ENE VV E++ +        P W          +W TRG         + +  IR  P      GFFVA
Sbjct:   18 KGSIKQLAFNSKKHDPKRTYALVCETLKYKPVLDEIIARSELLVLEKKLK----------ENL-ARVLVHDLLMSKRGLSISNGPIKECILRHKTRLNAEFVKLKVKKGVKSHEELALKN-PVSLPRWLRINTIKSTKDEVLQ-----GLGL----DK-------VSSIEELGPDKFYIDDCV-ENLIAIDPSFPIVENSLYKEGKVIIQDKASCFPAAVLAGLTGHVGDIIDGCAAPGNKTTHLAACF-----PKSHI--FAFERDAKRVQTL-------RKMVGISGANNVTIEHQDFTLTDPKSDLYRNVTHILLDPSCSGSGIVSRQDYLLGNEQDVTEDTERLENLCSFQSTILKHALQFPNCRHVTYSTCSVHRLENEQVVCEVLSQ-------EPDWKCNSLTKTLPNWKTRGIPEYCAQPSMAEGMIRCKPGAGGTIGFFVA 417
[Close]
BLAST of SMED30023422 vs. UniProt/SwissProt
Match: sp|Q63ZY6|NSN5C_HUMAN (Putative methyltransferase NSUN5C OS=Homo sapiens OX=9606 GN=NSUN5P2 PE=5 SV=2)

HSP 1 Score: 139.813 bits (351), Expect = 9.227e-36
Identity = 96/256 (37.50%), Postives = 131/256 (51.17%), Query Frame = -3 
Query:  324 ELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDRI 1082
            ELLVF     LH   L RA  +++QD+ASC+PA +LDP               KT+HL ++L  + K      +FAFD D  R  S+ + L       A           EDF  V P DPRY  V Y+ LDPSCSGSG+     R  E          RL +L  FQ   L HAL+FP+++R+VYS CS+  EENE +V++ +++    F+L+P    +   RG   F   + C+R SP   L  GFFVA  +R+
Sbjct:    3 ELLVFPAQTDLHEHPLYRAGHLILQDRASCLPAMLLDPRQAPMSWMPVPPQAIKTSHLAALLKNQGK------IFAFDLDARRLASMATLL-------AWAGVSCCELAEEDFLAVSPLDPRYREVHYVLLDPSCSGSGM---PSRQLEEPGAGTPSPVRLHALAGFQQRALCHALTFPSLQRLVYSMCSLCQEENEDMVQDALQQNPGAFRLAPA-LPARPHRGLSTFPGAEHCLRASPKTTLSGGFFVAVIERV 241
[Close]
BLAST of SMED30023422 vs. UniProt/SwissProt
Match: sp|Q8GYE8|NSUN5_ARATH (25S rRNA (cytosine-C(5))-methyltransferase NSUN5 OS=Arabidopsis thaliana OX=3702 GN=NSUN5 PE=1 SV=1)

HSP 1 Score: 141.354 bits (355), Expect = 1.991e-34
Identity = 119/391 (30.43%), Postives = 177/391 (45.27%), Query Frame = -3 
Query:  327 YDMLFGQATSNTSGCP--LISKMKVFKTILDELISENKLKTKEEILN-----HFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQL--EDFTKVDPTDPRYANVGYICLDPSCSGSG-IMRQVDRMAERNS---NNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSX-------XXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLF---KQCIRTSPSYDLCNGFFVACFDR 1430
            YD+LFG+ T +       L+   +   + L  L+   K+ + +++L      H +P         YVR+N L +   +A+                     Q LE    +++ + +PD      LLV    + LH  +LV   ++ +Q KAS + AA L P    +V+DAC+APGNKT HL +++  + K      + A + +E R K LE         H I  +   N ++   DF  ++P DP +A +  I LDPSCSGSG I  ++D +   +S   N   D  RL  L  FQ   L+HALSFP V+RVVYSTCS+              +   +  K  T F         W  RG  +F   +  +R  P  D   GFF+A F R
Sbjct:  177 YDILFGKDTPSIGDAEKFLMRHKEALLSGLATLLVRKKVDSVDQLLGSKLTGHLKPR--------YVRVNTLKMDVDSAV---------------------QELEKHYTVQKDETVPD------LLVLPPGSDLHAHRLVANGRIFLQGKASSMVAAALQPQAGWEVLDACSAPGNKTIHLAALMEGQGK------IIACELNEERVKRLE---------HTIKLSGASNIEVCHGDFLGLNPKDPSFAKIRAILLDPSCSGSGTITDRLDHLLPSHSEDNNMNYDSMRLHKLAVFQKKALAHALSFPKVERVVYSTCSIYQIENEDVVSSVLPLASSLGFKLATPF-------PQWQRRGLPVFAGSEHLLRMDPVED-KEGFFIALFVR 509
[Close]
BLAST of SMED30023422 vs. TrEMBL
Match: A0A4Z2CXK1 (Putative 28S rRNA (Cytosine-C(5))-methyltransferase OS=Schistosoma japonicum OX=6182 GN=EWB00_006686 PE=3 SV=1)

HSP 1 Score: 250.366 bits (638), Expect = 1.596e-71
Identity = 183/514 (35.60%), Postives = 267/514 (51.95%), Query Frame = -3 
Query:  327 LYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKL---GKIESKKSSRECESG-------TGCENCRIKVQIYDMLFGQATSNTSGCPLISKMKVFKTILDELISENKL--KTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSL--------------------ESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGI-MRQVDRMAE-RNSNNRVDQ----------QRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDS---------------WMTRGKKLFK--QCIRTSPSYDLCNGFFVACFDR 1685
            LYKEA  L C V   VC LK  L+  +F  DL+K+ A+ ++ + +  I+ +  +++ L    KI    S+ + ++          C +C + V I+D+L G+ TS+      I ++      + +L    KL  K  +  + H + E + + LP Y R+N L  T    +E     G   + Y      Y +F + +++L  G+F+ DYHL   LLVF++   LH  +L ++R +LIQDKASC    +L PD + DV+DACAAPGNKT+ L+S++S K+      ++FAFDRD  RF+ L                    +S  + +R     +Q   V     DF  VDP DP+++NV  I LDPSCSGSG+ +RQ D   + +NS  + D            RL  L N QAMLL HAL+FPNV+R+VYSTCS+  EENEAVV+E   +   +F L  IW ++               W  RG   ++   CIR+S   DL NGFFVA F R
Sbjct:    8 LYKEAAYLVCLVKGQVCRLKTCLYTHNFICDLRKIYALGSKTLDSYEILLQTLKQAGLQSTTKITHLSSNDQLKNNKDNNDVQQSCSHCHLMVLIHDLLKGKKTSHRFLLSYIRELTKDDFAVRKLRRAYKLVEKRSQSQITH-QGETRGL-LPCYARVNFLKTTLSDVVEKLETCGLKQVQYNRSETSYRKFRKKVRKLNRGEFLLDYHLPHMLLVFSSGTALHELELYKSRCILIQDKASCFSTEILQPDPNSDVLDACAAPGNKTSQLISMMSSKS------TVFAFDRDPNRFQCLTENLVANGVDRLSVIDWPNSDSKHNKHRKSLQSSQPF-VEASCTDFLSVDPYDPKFSNVQSILLDPSCSGSGLSIRQPDGEQQLKNSQLKGDYSTDTYNEEYLSRLKRLSNLQAMLLRHALNFPNVQRIVYSTCSIHPEENEAVVQENAIRVSDKFYLETIWPNTISLNSLDNITATPRVWKHRGLSEYQCESCIRSSQK-DLTNGFFVALFVR 511
[Close]
BLAST of SMED30023422 vs. TrEMBL
Match: H2KQ68 (Putative methyltransferase NSUN5 OS=Clonorchis sinensis OX=79923 GN=CLF_103354 PE=3 SV=1)

HSP 1 Score: 245.743 bits (626), Expect = 3.772e-70
Identity = 186/534 (34.83%), Postives = 278/534 (52.06%), Query Frame = -3 
Query:  297 LYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKL-----------GKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSN-----------TSGCPLISKMK-VFKTILDELISENKLKTKE-EILNHFRP---EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALST----------------YRSPHAITQTVTVNTQ------LEDFTKVDPTDPRYANVGYICLDPSCSGSGIM-RQVD-----------RMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIW----TDS---WMTRGKKLF--KQCIRTSPSYDLCNGFFVACFDRIRD-HLPSDNK 1685
            LY EA  L C V    C LK+ L+++ F++DL+KL A+  + + + ++++E  ++SKL             IE + SS E    TGC +C + V ++D+L G + SN           T     IS+ +  +K +        K + KE E     RP    D  + LP Y R+N L    ++ ++   +  Y  L    K  +     + L++L++  F  DYHL + LL+F + ++L+    V +RK++IQDKASCI   V+ P+ + DV+DACAAPGNKT  L+ ++S    P++  ++FA DRD  RF++L + L +                   P   T T    +Q       +DF  +DP D +++ V  I LDPSCSGSG++ RQ +            M E +       +RL  L N QA LL HALSF NV+RVVYSTCSV  EENEAVV E +E+F  +F+L  IW    +D+   W+ RG      + C+R SP  DL NGFF+A F R+ + H  S++K
Sbjct:   13 LYSEASFLVCNVLGKKCRLKSALYENDFTTDLRKLYALACKTLDSFSLLHETVKQSKLVHRHPVEHIPTKSIEGRGSSSE-PRLTGCHHCLLYVTLHDLLLGSSRSNYKIWAKELYLVTQDTGAISRFRRAYKVV-------KKARKKENEHTACIRPGNQNDTRLLLPCYARVNRLRADLESVLKELQSEQYTELQTTGKRTR-----KMLRKLEDNQFYVDYHLSDNLLIFTHGSLLYKLPAVTSRKLIIQDKASCIVPEVVRPNPNADVLDACAAPGNKTLQLIEMMS----PQA--TVFAIDRDPTRFRTLCNNLHSSGVQRLSISGSIIVDNLPDPENATTTKRPCSQPRVEAICQDFLSLDPMDSKFSRVESILLDPSCSGSGLVARQPEGTGSVLSSGYSNMGEDDMKGEDISRRLERLSNLQAQLLRHALSFQNVRRVVYSTCSVRSEENEAVVLENLERFRGQFKLETIWPAGNSDARRRWLHRGLSEMGCEACLRASPESDLTNGFFIASFVRVSESHTESESK 527
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BLAST of SMED30023422 vs. TrEMBL
Match: C7TXW0 (Putative methyltransferase NSUN5 OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 246.514 bits (628), Expect = 4.604e-70
Identity = 181/514 (35.21%), Postives = 266/514 (51.75%), Query Frame = -3 
Query:  327 LYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKL---GKIESKKSSRECESG-------TGCENCRIKVQIYDMLFGQATSNTSGCPLISKMKVFKTILDELISENKL--KTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSL--------------------ESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGI-MRQVDRMAE-RNSNNRVDQ----------QRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDS---------------WMTRGKKLFK--QCIRTSPSYDLCNGFFVACFDR 1685
            LYKEA  L C V   VC LK  L+  +F  DL+K+ A+ ++ + +  I+ +  +++ L    KI    S+ + ++          C +C + V I+D+L G+ TS+      I ++      + +L    KL  K  +  + H + E + + LP Y R+N L  T    +E     G   + Y      Y +F + +++L  G+F+ DYH    LLVF++   L+  +L ++R +LIQDKASC    +L PD + DV+DACAAPGNKT+ L+S++S K+      ++FAFDRD  RF+ L                    +S  + +R     +Q   V     DF  VDP DP+++NV  I LDPSCSGSG+ +RQ D   + +NS  + D            RL  L N QAMLL HAL+FPNV+R+VYSTCS+  EENEAVV+E   +   +F L  IW ++               W  RG   ++   CIR+S   DL NGFFVA F R
Sbjct:    8 LYKEAAYLVCLVKGQVCRLKTCLYTHNFICDLRKIYALGSKTLDSYEILFQTLKQAGLQSTTKITHLSSNDQWKNNKDNNDVQQSCSHCHLMVLIHDLLKGKKTSHRFLISYIRELTKDDFAVRKLRRAYKLVEKRSQSQITH-QGETRGL-LPCYARVNFLKTTLSDVVEKLETCGLKQVQYNRSETSYRKFRKKVRKLNRGEFLLDYHFPHMLLVFSSGTALYELELYKSRCILIQDKASCFSTEILQPDPNSDVLDACAAPGNKTSQLISMMSSKS------TVFAFDRDPNRFQCLTENLVANGVDRLSVIDWPNSDSKHNKHRKSLQSSQPF-VEASCTDFLSVDPYDPKFSNVQSILLDPSCSGSGLSIRQPDGEQQLKNSQLKGDYSTDTYNEEYLSRLKRLSNLQAMLLRHALNFPNVQRIVYSTCSIHPEENEAVVQENANRVSDKFYLETIWPNTIPLNSVDNITATPQVWKHRGLSEYQCESCIRSSQK-DLTNGFFVALFVR 511
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BLAST of SMED30023422 vs. TrEMBL
Match: A0A4S2M950 (SAM_MT_RSMB_NOP domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_001759 PE=3 SV=1)

HSP 1 Score: 244.588 bits (623), Expect = 1.351e-69
Identity = 182/537 (33.89%), Postives = 271/537 (50.47%), Query Frame = -3 
Query:  294 LYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGK-----------IESKKSSRECESGTGCENCRIKVQIYDMLFGQATSN-----------TSGCPLISKMK-VFKTILDELISENKLKTKEEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSL--------------ESALSTYRSPHAITQTVT--------VNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIM-RQVD-----------RMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIW----TDS---WMTRGKKLF--KQCIRTSPSYDLCNGFFVACFDRIRD-------HLPSDNKP 1685
            LY EA  L C V    C LK+ L+ + FS+DL+KL A+  + + + ++++E  ++SKL +           I+   SS E    TGC +C + V ++D+L G + SN           T     IS+ +  +K +      EN+   +   +      D  + LP Y R+N L    ++ ++   +  Y  L    +  +     + L++L +  F  DYHL + LL+F + ++L+    V +RK++IQDKASCI   V+ P+ + DV+DACAAPGNKT  L+ ++S    P++  ++FA DRD  RF++L                +L     P     T T        V    +DF  +DP D +++ V  I LDPSCSGSG++ RQ +            M E +       +RL  L N QA LL HALSF NV+RVVYSTCSV  EENEAVV E +E+F  +F+L  IW    +D+   W+ RG      + C+R SP  DL NGFF+A F R+ +         P D KP
Sbjct:   13 LYSEASFLVCNVLGKKCRLKSALYGNEFSTDLRKLYALACKTLDSLSLLHETVKQSKLVRRHPVEHIPTKSIDGTGSSSESRL-TGCRHCLLYVTLHDLLLGSSRSNYKIWVKELYLVTQDTGAISRFRRAYKVVKKARKKENE---RTACIRPGNQNDARLLLPCYARVNRLRADLESVLKELQSEQYAELQTPGRRTR-----KMLRKLGDNQFYVDYHLSDNLLIFAHGSLLYKLPAVTSRKLIIQDKASCIVPEVVRPNPNADVLDACAAPGNKTLQLIEMMS----PQA--TVFAIDRDPTRFRTLCNNLHSSGVQRLSVSGSLIVDNLPDPENTTTTKLPCSQPRVEAICQDFLSLDPMDSKFSRVESILLDPSCSGSGLVARQPEGTGSVLSSGYSNMGEDDMKGEDISRRLERLSNLQAQLLRHALSFQNVRRVVYSTCSVRSEENEAVVLENLERFRGQFELETIWPADNSDARRRWLHRGLSEMGCEACLRASPESDLTNGFFIASFVRVSEPHTESGSKRPGDEKP 534
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BLAST of SMED30023422 vs. TrEMBL
Match: A0A1S8WPU7 (NOL1/NOP2/sun family protein OS=Opisthorchis viverrini OX=6198 GN=X801_07743 PE=3 SV=1)

HSP 1 Score: 240.736 bits (613), Expect = 3.318e-68
Identity = 179/524 (34.16%), Postives = 268/524 (51.15%), Query Frame = -3 
Query:  318 LYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGK---IESKKSSRECESG-------TGCENCRIKVQIYDMLFGQATSN-----------TSGCPLISKMK-VFKTILDELISENKLKTKEEILNHFRPE---DKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESAL----------------------STYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIM-RQVD-----------RMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIW----TDS---WMTRGKKLF--KQCIRTSPSYDLCNGFFVACFDRIRD 1685
            LY EA  L C V    C LK  L+ + FS+DL+KL A+  + + + ++++E  ++SKL +   +E   S R   +G       TGC +C + V ++D+L G + SN           T     IS+ +  +K +      +   K + E     RP+   D  + LP Y R+N L    ++ ++   +  Y  L       +     + L++L++  F  DYHL   LL+F + ++L+    V +RK++IQDKASCI   VL P+ + DV+DACAAPGNKT  L+ +++    P++  ++FA DRD  RF++L + L                       T R+         V    +DF  +DP D +++ V  I LDPSCSGSG++ RQ +            M E +       +RL  L N QA LL HALSF NV+RVVYSTCSV  EENEAVV E +E+F  +F+L  IW    +D+   W+ RG      + C+R SP  DL NGFF+A F R+ +
Sbjct:   11 LYSEASFLVCNVLGKQCRLKTALYGNEFSTDLRKLYALACKTLDSLSLLHETVKQSKLVRRYPVEHIPSKRTDGTGSSSESRLTGCRHCLLYVTLHDLLLGSSRSNYKIWAKEIYLVTQDKGAISRFRHAYKVV------KKARKKENERTACIRPDNQNDARLLLPCYARVNRLRADLESVLKELQSEQYAELQAPGIRTR-----KMLRKLEDNQFYVDYHLSHSLLIFAHGSLLYKLPAVTSRKLIIQDKASCIVPEVLRPNPNADVLDACAAPGNKTLQLIEMMT----PQA--TVFAIDRDPTRFRTLCNNLHSSGVQRLSISGSLIVDNLPDPETARTTKLPCSQPRVEAICQDFLSLDPMDLKFSRVESILLDPSCSGSGLVARQPEGTGPVLSSGYSNMGEDDMKGEDISRRLERLSNLQAQLLRHALSFQNVRRVVYSTCSVRSEENEAVVLENLERFHGQFKLETIWPADNSDARRRWLHRGLSEMGCEACLRASPESDLTNGFFIASFVRVSE 517
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BLAST of SMED30023422 vs. Ensembl Cavefish
Match: nsun5 (NOP2/Sun RNA methyltransferase 5 [Source:ZFIN;Acc:ZDB-GENE-040426-2476])

HSP 1 Score: 213.386 bits (542), Expect = 1.693e-62
Identity = 160/428 (37.38%), Postives = 225/428 (52.57%), Query Frame = -3 
Query:  327 SDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGCPLISKMKVFKTILDELISENKLKTK----EEILNHFRPEDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFKQCIRTSPSYDLCNGFFVACFDR 1598
            +++K+L A+V E  K  +++ EI        IES K  +E    T  +    KV +YD+LFGQ      G    + M   ++ L   ++  K+K K    E++L    PE     +P YVR+N+L  T +  I++    G++   Y+ ++ +    +E L  L    FM D HL  ELLVF      H   L +A  +++QDKASC+PA +LDP    +VIDACAAPGNKT+HL +I+  K K      LFAFD D  R     S +ST      +T     N   +DF KVDP  P Y  V ++ LDPSCSGSG++   D      S+   D +RL +L  FQ   L HAL FP ++RVVYSTCS+   ENE VV   ++K    F+L  ++ + W  RG     QC+R S    L +GFFVA  +R
Sbjct:   23 NNIKQLFALVCETQKYSSVLQEI--------IESTKFLKE----TKLKLNLAKVMVYDLLFGQGVK--CGGAWKAMMMKHRSRLQAALARMKVKQKVSRNEDLLPPGVPE-----IPRYVRVNMLKTTVEDVIDYLKREGFS---YQGRASR----IEDLCHLSGKAFMGDVHL-RELLVFPAKMDFHDHYLYKAGHIILQDKASCLPAYLLDPPVGGNVIDACAAPGNKTSHLAAIMKNKGK------LFAFDLDVKRL----STMSTLLLRAGVTCHKLAN---QDFLKVDPLSPEYKEVKHVLLDPSCSGSGMVCLPD-----GSSEEQDSERLQALAAFQLRCLDHALQFPQLQRVVYSTCSIHSTENEEVVSACLQK-NPGFRLVHLFPE-WPERGHAPLTQCLRASTKETLTHGFFVAMLER 403
[Close]
BLAST of SMED30023422 vs. Ensembl Cavefish
Match: nop2 (NOP2 nucleolar protein [Source:NCBI gene;Acc:103028554])

HSP 1 Score: 55.4546 bits (132), Expect = 1.339e-7
Identity = 83/341 (24.34%), Postives = 135/341 (39.59%), Query Frame = -3 
Query:  306 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKR-----VVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFKQCIRTSPSYDLC----------NGFFVACFDRIRDHLPS 1283
            E   I  P+ +R N L   ++   +  +N G N           +   +W K                L++F++S  +       A   ++Q  +S +P   L P     V+D  +APG KTT++  ++           + A D    R KS+   +        +T ++  N     F KV            + LD  CSG+G++ +    A + S +  D QR  S H  Q  L+  A+   N +      +VY TCS+  EENE VV+  ++K     +L P   D +   G   FK+  R  PS  L           +GFFVA   +  + +P+
Sbjct:  272 EANEIQRPVTIRTNTLKTRRRDLAQALINRGVNL----------DPLGKWSKV--------------GLVIFDSSVPIGATPEYLAGHYMLQGASSLLPVMALSPQEGETVLDMSSAPGGKTTYMAQLMRNTG------VIIANDASADRLKSVVGNIHRL----GVTNSIICNYDGRQFPKV------MGGFDRVLLDAPCSGTGVISK--DPAVKTSKDDSDIQR--SAH-LQKELILAAIDSVNAESQTGGYLVYCTCSIMVEENEWVVDYALKK--RNVKLVPTGLD-FGKEGFTRFKEK-RFHPSLKLTRRFYPHSHNMDGFFVAKLKKFSNTIPT 563
[Close]
BLAST of SMED30023422 vs. Ensembl Cavefish
Match: nop2 (NOP2 nucleolar protein [Source:NCBI gene;Acc:103028554])

HSP 1 Score: 55.4546 bits (132), Expect = 1.409e-7
Identity = 83/341 (24.34%), Postives = 135/341 (39.59%), Query Frame = -3 
Query:  306 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKR-----VVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFKQCIRTSPSYDLC----------NGFFVACFDRIRDHLPS 1283
            E   I  P+ +R N L   ++   +  +N G N           +   +W K                L++F++S  +       A   ++Q  +S +P   L P     V+D  +APG KTT++  ++           + A D    R KS+   +        +T ++  N     F KV            + LD  CSG+G++ +    A + S +  D QR  S H  Q  L+  A+   N +      +VY TCS+  EENE VV+  ++K     +L P   D +   G   FK+  R  PS  L           +GFFVA   +  + +P+
Sbjct:  304 EANEIQRPVTIRTNTLKTRRRDLAQALINRGVNL----------DPLGKWSKV--------------GLVIFDSSVPIGATPEYLAGHYMLQGASSLLPVMALSPQEGETVLDMSSAPGGKTTYMAQLMRNTG------VIIANDASADRLKSVVGNIHRL----GVTNSIICNYDGRQFPKV------MGGFDRVLLDAPCSGTGVISK--DPAVKTSKDDSDIQR--SAH-LQKELILAAIDSVNAESQTGGYLVYCTCSIMVEENEWVVDYALKK--RNVKLVPTGLD-FGKEGFTRFKEK-RFHPSLKLTRRFYPHSHNMDGFFVAKLKKFSNTIPT 595
[Close]
BLAST of SMED30023422 vs. Ensembl Cavefish
Match: nop2 (NOP2 nucleolar protein [Source:NCBI gene;Acc:103028554])

HSP 1 Score: 55.4546 bits (132), Expect = 1.445e-7
Identity = 83/341 (24.34%), Postives = 135/341 (39.59%), Query Frame = -3 
Query:  306 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKR-----VVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFKQCIRTSPSYDLC----------NGFFVACFDRIRDHLPS 1283
            E   I  P+ +R N L   ++   +  +N G N           +   +W K                L++F++S  +       A   ++Q  +S +P   L P     V+D  +APG KTT++  ++           + A D    R KS+   +        +T ++  N     F KV            + LD  CSG+G++ +    A + S +  D QR  S H  Q  L+  A+   N +      +VY TCS+  EENE VV+  ++K     +L P   D +   G   FK+  R  PS  L           +GFFVA   +  + +P+
Sbjct:  304 EANEIQRPVTIRTNTLKTRRRDLAQALINRGVNL----------DPLGKWSKV--------------GLVIFDSSVPIGATPEYLAGHYMLQGASSLLPVMALSPQEGETVLDMSSAPGGKTTYMAQLMRNTG------VIIANDASADRLKSVVGNIHRL----GVTNSIICNYDGRQFPKV------MGGFDRVLLDAPCSGTGVISK--DPAVKTSKDDSDIQR--SAH-LQKELILAAIDSVNAESQTGGYLVYCTCSIMVEENEWVVDYALKK--RNVKLVPTGLD-FGKEGFTRFKEK-RFHPSLKLTRRFYPHSHNMDGFFVAKLKKFSNTIPT 595
[Close]
BLAST of SMED30023422 vs. Ensembl Cavefish
Match: ENSAMXT00000034509.1 (pep primary_assembly:Astyanax_mexicanus-2.0:2:32997824:33020032:1 gene:ENSAMXG00000034355.1 transcript:ENSAMXT00000034509.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 49.6766 bits (117), Expect = 7.306e-6
Identity = 69/290 (23.79%), Postives = 117/290 (40.34%), Query Frame = -3 
Query:  555 FKTILDELISENKLKTKEEILNHFRPE------DKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAV--LHTDKLVRARKVLIQDKASC-IPAA---VLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERN---------SNNRVDQQRLTSLHNFQAMLLSHAL 1361
            FKT L   ++  ++K     ++   PE      +++ +LP+Y  IN L  + +   +   +AG++ +  E +             L+   F  D H  ++LLVF       L+ + L+   +++IQDK+ C +P A   +LD D  + +  + +A              KN     + +   +R       L+  LS+            V    E F  VD  D R   V  + L P CS S +   VD + + N         S+  V + RL +L + Q   L HAL
Sbjct:  170 FKTKLAASLARCRIKHDLLTIDSILPESVRLRQERASNLPVYAWINTLRTSMEEVCDVLSSAGFSRVHSEGR-------------LEGRTFRLDTHC-QDLLVFPACVRGDLYKNGLLSDYRLIIQDKSCCMVPWALRPLLDEDGGVLLAGSFSAATVAHMVAAVAAVSKNTQSVRVLVCVGERSPAETNELQELLSSM--------GCNVKLLFESFNDVDVGDARLQKVRIVLLTPQCSLSAVSNPVDFLLQENGDTELLQDLSHGSVSRSRLETLVSKQRRDLQHAL 437
[Close]
BLAST of SMED30023422 vs. Ensembl Sea Lamprey
Match: nop2 (NOP2 nucleolar protein homolog (yeast) [Source:ZFIN;Acc:ZDB-GENE-050309-7])

HSP 1 Score: 54.299 bits (129), Expect = 4.611e-8
Identity = 79/340 (23.24%), Postives = 136/340 (40.00%), Query Frame = -3 
Query:  309 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKR-----VVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFKQCIRTSPSYDLC----------NGFFVACFDRIRDHLP 1283
            E   +  P+ +R N L   ++   +  +N G N           +   +W K                L++F++S  +       A   ++Q  +S +P   L P  +  ++D CAAPG KT++   ++          ++ A D +  R KS+   L        +T ++  N       KV       +    + LD  CSG+GI+ +     + +     D++ +    + Q  LL  A+   +        +VY TCSVT EENE VV+  + K     +L P   D +   G   FK+  R  PS  L           +GFFV+ F ++ + +P
Sbjct:  103 EANEVHRPVTIRTNTLKTRRRELAQALINRGVNL----------DPLGKWSKV--------------GLVIFDSSVPVGATPEYLAGHYMLQGASSLLPVMALAPQENEKLLDMCAAPGGKTSYAAQLMRNTG------AIVANDVNSERLKSVVGNLHRL----GVTNSIVCNYDGRALAKV------MSGFDRVLLDAPCSGTGIISK-----DPSVKTSKDEKDILRCAHLQKQLLLTAIDCLDAASTTGGFLVYCTCSVTVEENEWVVDYALRK--RNVKLVPTGLD-FGKEGFTRFKE-RRFHPSLKLTRRFYPHTHNMDGFFVSKFKKLSNDIP 393
[Close]
BLAST of SMED30023422 vs. Ensembl Sea Lamprey
Match: nop2 (NOP2 nucleolar protein homolog (yeast) [Source:ZFIN;Acc:ZDB-GENE-050309-7])

HSP 1 Score: 51.6026 bits (122), Expect = 3.175e-7
Identity = 54/262 (20.61%), Postives = 100/262 (38.17%), Query Frame = -3 
Query:  513 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKR-----VVYSTCS 1283
            E   +  P+ +R N L   ++   +  +N G N           +   +W K                L++F++S  +       A   ++Q  +S +P   L P  +  ++D CAAPG KT++   ++          ++ A D +  R KS+   L        +T ++  N       KV       +    + LD  CSG+GI+ +     + +     D++ +    + Q  LL  A+   +        +VY TCS
Sbjct:  112 EANEVHRPVTIRTNTLKTRRRELAQALINRGVNL----------DPLGKWSKV--------------GLVIFDSSVPVGATPEYLAGHYMLQGASSLLPVMALAPQENEKLLDMCAAPGGKTSYAAQLMRNTG------AIVANDVNSERLKSVVGNLHRL----GVTNSIVCNYDGRALAKV------MSGFDRVLLDAPCSGTGIISK-----DPSVKTSKDEKDILRCAHLQKQLLLTAIDCLDAASTTGGFLVYCTCS 328
[Close]
BLAST of SMED30023422 vs. Ensembl Yeast
Match: RCM1 (rRNA m5C methyltransferase; methylates cytosine at position 2278 of 25S rRNA while Nop2p methylates cytosine at position 2870; contains seven beta-strand methyltransferase motif; localized to the nucleolus; interacts with Trm112p; homolog of NSUN5A, a human gene which is deleted in Williams-Beuren Syndrome [Source:SGD;Acc:S000004967])

HSP 1 Score: 124.79 bits (312), Expect = 5.632e-31
Identity = 120/391 (30.69%), Postives = 178/391 (45.52%), Query Frame = -3 
Query:  327 FKTILDELISENKLKTK-EEILNHFRPEDKSIDLPI--YVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQ---------------------VDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXX-----XXXEKFGTEFQLSPIWTDSWMTRGK-----------------KLFKQCIRTSPSYDLCNGFFVACFDR 1361
            FK+ L   + + KLK K  E+      ED S DLP   ++RIN L        E  +          +   K+   ++   EL  G    D  +   L   + S  +   +L +  K++IQD+ASC PA +L+P     VID+C+APGNKTTH  S +  +   ++   ++AF++D  R K L+  +         +  ++VN  + DFTK+  T  +Y +V    +DPSCSGSGI  +                      D   E  +   + Q RL  L +FQ  ++ HA+SFP  K++VYSTCS+  EENE VV      + V ++G +         SW  RGK                 +L + CIR  P  D   GFF  CF+R
Sbjct:  117 FKSPLHSEMVKLKLKLKVRELSELVLSEDISNDLPPVRWIRINPLKCHPNGETEPVL---------AELRKKFTLKVDKWSELVPGSIYYDEFI-PNLFGIHPSDKITAHELYKHGKIIIQDRASCFPAHILNPGPSDIVIDSCSAPGNKTTHTASYIYPEPPKDNNTRIYAFEKDPERAKVLQKMIKI----AGCSPNISVN--VGDFTKLA-TPEKYKDVTCFIVDPSCSGSGIFGRKFFDSFNRRKIDDKDDDGGIVPDEQEEFIAKEEL-QTRLAKLSSFQFQMVKHAMSFPAAKKIVYSTCSIHAEENERVVIDLLLDKSVREWGWKVAPKREVIPSWPRRGKVEEFEEVFRDGVTYDPQQLAEGCIRALPKSDGGIGFFAVCFER 489
[Close]
BLAST of SMED30023422 vs. Ensembl Yeast
Match: NOP2 (rRNA m5C methyltransferase; methylates cytosine at position 2870 of 25S rRNA; has an essential function independent of rRNA methylation; contains seven beta-strand methyltransferase motif; essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; localized to the nucleolus; constituent of 66S pre-ribosomal particles; rRNA methylation defect and lethality are functionally complemented by human NOP2, a gene upregulated in cancer [Source:SGD;Acc:S000005005])

HSP 1 Score: 63.1586 bits (152), Expect = 6.673e-11
Identity = 94/362 (25.97%), Postives = 144/362 (39.78%), Query Frame = -3 
Query:  285 EEILNHFRP-------EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFP-NVKR---VVYSTCSXXXXXXXXXXXXXXEK------FGTEFQLSPIWTDSWMTRGKKL---FKQCIRTSPSYDLCNGFFVACFDRIRDHLPSDNKPKPK 1310
            E++ N F P       E   I  PI +R N L   ++   +  VN G N                W K                L +F++   +       A   ++Q  +S +P   LDP  +  ++D  AAPG KTT++ +++           +FA D ++ R KSL + +         T T+  N    +F KV            I LD  CSG+G++ +   +      +R ++  +   H  + +LLS   S   N K    +VYSTCSV  EE+EAV++  + K        T   +      S+  RGKK     K   R  P     +GFFVA F +I      DN+   K
Sbjct:  247 EKLFNLFSPAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVNL----------QPIGSWTKV--------------GLQIFDSQVPIGATPEYLAGHYILQAASSFLPVIALDPHENERILDMAAAPGGKTTYISAMMKNTG------CVFANDANKSRTKSLIANIHRL----GCTNTIVCNYDAREFPKV------IGGFDRILLDAPCSGTGVIGKDQSV----KVSRTEKDFIQIPHLQKQLLLSAIDSVDCNSKHGGVIVYSTCSVAVEEDEAVIDYALRKRPNVKLVDTGLAIGKEAFTSY--RGKKFHPSVKLARRYYPHTYNVDGFFVAKFQKIGPSSFDDNQASAK 562
[Close]
BLAST of SMED30023422 vs. Ensembl Yeast
Match: NCL1 (S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase; methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; increases proportion of tRNALeu(CAA) with m5C at wobble position in response to hydrogen peroxide, causing selective translation of mRNA from genes enriched in TTG codon; loss of NCL1 confers hypersensitivity to oxidative stress; similar to Nop2p and human proliferation associated nucleolar protein p120 [Source:SGD;Acc:S000000120])

HSP 1 Score: 55.4546 bits (132), Expect = 1.672e-8
Identity = 75/275 (27.27%), Postives = 108/275 (39.27%), Query Frame = -3 
Query:  318 QDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKV-----DPTDPRYANVGYICLDPSCSGSGIMRQ-VDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALS-FPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLS------------------PIWT--------------DSWMT-----RGKKLFKQCIRTSPSYDLCNGFFVACFDRIRD 1010
            Q+  S IP  VL+      V+D CAAPG+KT  L+  L  K+  E    + A D D  R   L   L    S       + VN   + F ++                 I  D  CSG G MR+ V+   + N+      Q    LH  Q  +L+  L    N  R+VYSTCS+   ENEAVV E + K+G + +L                   P++               DS+ +       K   + C+R  P      GFF+  F+++ D
Sbjct:  150 QEAVSMIPPIVLEVKPHHTVLDMCAAPGSKTAQLIEAL-HKDTDEPSGFVVANDADARRSHMLVHQLKRLNS----ANLMVVNHDAQFFPRIRLHGNSNNKNDVLKFDRILCDVPCSGDGTMRKNVNVWKDWNT------QAGLGLHAVQLNILNRGLHLLKNNGRLVYSTCSLNPIENEAVVAEALRKWGDKIRLVNCDDKLPGLIRSKGVSKWPVYDRNLTEKTKGDEGTLDSFFSPSEEEASKFNLQNCMRVYPHQQNTGGFFITVFEKVED 413
[Close]
BLAST of SMED30023422 vs. Ensembl Nematostella
Match: EDO45380 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT21])

HSP 1 Score: 207.608 bits (527), Expect = 1.592e-60
Identity = 153/458 (33.41%), Postives = 235/458 (51.31%), Query Frame = -3 
Query:  327 LYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGCPLISKMKVFKTILDELISENKLKTKEEILNHFRPED--KSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFK---QCIRTSPSYDLCNGFFVACFDR 1685
            LY  A  +  KV      +K+ + +S F++  KKL A+V E +K + ++ +IF+++K  K E +            ++    V +Y++LFG       G      +   K+ L   +++ K+K K        P+    +  +P Y RIN LL T    I+HF    Y+ +   DK +    ++E  K   +   +P      E+LVF  S  LH   L     +L+QDKASC+PA V+       VIDACAAPGNK++HL + L+   +      +F+FD    R   ++  +              V T+ + F  VDP   +Y NV YI +DPSCSGSGI+ ++D +      + + QQRL SL +FQ  +L+HA SFP VK+V YSTCS+  +ENE VV + ++    +F+L+    +SW +RG  +F+   +C+R SP  D  NGFFVA F R
Sbjct:    4 LYGSAAKVLEKVLHKKGTVKSLVIESEFANK-KKLYALVCETLKYRQVIEDIFEQTKFLKCEKQ-----------LKHSFALVLVYELLFGHGLK--CGGKFKQSIARNKSSLQSALAKVKIKAKVSRNKDLLPKSVQTAGTIPRYARINTLLTTADKVIKHFQEESYHLVPSTDKRL----YVEGSKIFAQDPHIP------EVLVFPPSTDLHDHTLYINGHILLQDKASCLPAHVISLPPGAHVIDACAAPGNKSSHLAAKLNNNGR------VFSFDISASRLAVMQKQMKK-------AGATCVVTEHKSFLDVDPRSSQYRNVEYIVVDPSCSGSGIISRLDGLVSDEQEDDL-QQRLESLADFQLSVLTHAFSFPAVKKVAYSTCSIHSQENEDVVHKALKVSQGQFELAHAL-ESWPSRGLPVFQGAEKCLRASPESDHTNGFFVALFQR 422
[Close]
BLAST of SMED30023422 vs. Ensembl Nematostella
Match: EDO40895 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5Z9])

HSP 1 Score: 60.077 bits (144), Expect = 1.130e-9
Identity = 61/261 (23.37%), Postives = 103/261 (39.46%), Query Frame = -3 
Query:  513 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSF----PNVKRVVYSTCS 1283
            E   +  P+ +R N L   ++   +  +N G N     D   K+++                      L+V+++S  +       A   +IQ  +S +P   L P     V+D CAAPG KTT+L +++           + A D  + R K+L + +        +T TV  N     F KV              LD  CSG+G++ +   +      N+ ++  L   H  + ++L+   S     P    +VYSTCS
Sbjct:  120 EANEVHRPVTIRTNSLKTRRRDLAQALINRGVNL----DPVGKWSKV--------------------GLVVYDSSVPIGATPEYLAGHYMIQGSSSMLPVMALAPQEKERVLDMCAAPGGKTTYLAALMKNTG------IVVANDAKKERTKALVANIHRL----GVTNTVVCNYDGRAFPKV------MGGFDRTLLDAPCSGTGVISKDPSV----KTNKTEKDILRCSHVQKELILAAIDSVDAKSPTGGYIVYSTCS 336
[Close]
BLAST of SMED30023422 vs. Ensembl Nematostella
Match: EDO42070 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2N2])

HSP 1 Score: 55.8398 bits (133), Expect = 9.345e-9
Identity = 48/166 (28.92%), Postives = 71/166 (42.77%), Query Frame = -3 
Query:  513 DKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYIC-LDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCS 1007
            D AS +P   LD   D  V+D CA+PG KT  ++ +LS++        L A +  + R + L   +  Y  P   T           F  ++P       V   C  D  C  SG   Q D  +E+ S      Q+ + L N   +++S   S  +  RVVYSTC+
Sbjct:   12 DAASLLPVICLDVGPDSTVLDMCASPGGKTVAMMQLLSERG------GLVANEPTQSRRRKLRKVIQEY-IPKGQTNITIRGMDGTKFGGLEPCSYDRILVDAPCSTDRHCLRSGF--QTDSWSEKKS------QKFSQLQN--KLVMSALGSLTSDGRVVYSTCT 160
[Close]
BLAST of SMED30023422 vs. Ensembl Nematostella
Match: EDO31651 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXC0])

HSP 1 Score: 55.8398 bits (133), Expect = 3.382e-8
Identity = 71/290 (24.48%), Postives = 115/290 (39.66%), Query Frame = -3 
Query:  513 PIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAV--LHTDKLVRARKVLIQDKASCIP-----------------AAVLDPDTDM--------DVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRD-----EIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHN-------FQAM-LLSHALSFPNVKRVVYSTCS 1262
            P+Y R+N L  + +  +      GY     E+KS           +L   +F+ D H  + LLVF+  A   LH + L     ++IQDK++ I                  A +L P  DM        D+I      GN T +L S++     P+  +  F    D     + + + L +   T+   H              F    P D R+  V  I ++  CS +GI+  VD + +   +  + +     L N       FQ + +L HA+SFP ++ +VY T S
Sbjct:   79 PVYARVNTLKSSLEDVMARLQKDGYVL---EEKSPDSED------QLTGKNFISDEHF-DNLLVFSAEAKFDLHGNDLTNEGCLVIQDKSTVISVEVVRSFVNEVSSQKEKANILIPGADMKKMLGDGDDIIQTHVESGNITAYLSSVIH----PDRTVFTFGATPDTKGHLQNKMEKLGARNVTFLEEH--------------FLDAIPNDERFRKVKIIVVNVPCSKTGIVNPVDFVLQEGVSASIKELARGGLDNSKIRGLAFQHLGVLKHAMSFPLLQGIVYITRS 340
[Close]
BLAST of SMED30023422 vs. Ensembl Nematostella
Match: EDO39248 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAM8])

HSP 1 Score: 53.9138 bits (128), Expect = 1.601e-7
Identity = 48/170 (28.24%), Postives = 73/170 (42.94%), Query Frame = -3 
Query:  513 QDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPIS---LFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNV-KRVVYSTCS 1010
            Q+  S IP  ++D      ++D CAAPG+KT+ ++ +L      E+ I+   + A +    R   L       RSP  +      +T      K +  D        I  D  CSG G MR+   +      N+   Q   SLH  Q  +L+ A+    V  R+VYSTC+
Sbjct:  122 QEAVSMIPPLLMDIKPGQKILDTCAAPGSKTSQIIEMLHGDK--ETGIAEGLVIANELQNKRCYMLIHQSKRLRSPSCVITNHDASTYPTLHVKKENGDRTPLLFDRILCDVPCSGDGTMRKNPLIW-----NKWTPQLGVSLHRTQLRILARAMEMLEVGGRIVYSTCT 284
[Close]
BLAST of SMED30023422 vs. Ensembl Medaka
Match: nsun5 (NOP2/Sun RNA methyltransferase 5 [Source:NCBI gene;Acc:101162047])

HSP 1 Score: 198.364 bits (503), Expect = 1.818e-56
Identity = 158/468 (33.76%), Postives = 238/468 (50.85%), Query Frame = -3 
Query:  306 INLYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIKNKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQATSNTSGCPLISKMKVFKTILDELISENKLKTKEEILNHFRPEDKSI----DLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQL--EDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFKQCIRTSPSYDLCNGFFVACFDRIRDHLPS 1691
            + LY +A  +  K       LK  ++ S F  ++K+L A+V E  +  +++ +I        IES K  ++ +          +V +YD+L GQ      G    + M   +  L   ++  K+K K        P +  +     LP YVR+N L  T +  +++    GY    Y+ ++ + +        LKE  F+ D  L  ELLVF++    H   L +A  +++QDKASC+PA +L P +   VIDACAAPGNKT+HL +I+  K K      LFAFD D  R  ++ + L        +   VT   QL  +DF KV+P  P+Y +V Y+ LDPSCSGSG++   DR       +  DQ RL SL  FQ   L+HA+ FP +KR+VYSTCS+  +ENE V+   +++  + F+L P+    W  RG     QC+R S S    +GFFVA  ++  + L S
Sbjct:    1 MALYVKAAEVLEKAERKQGALKTLVYDSKFK-NIKQLFALVCETQRFSSVLLDI--------IESTKLLKQTKLKLHLA----QVLVYDLLMGQGLK--CGGSFKTTMMKHRPRLQAELARMKVKRKVSRNEDLLPAEAQLPSGEQLPRYVRVNTLKTTVEDVVDYLKRDGYT---YQGQASRLDDL-----TLKEKSFVKDLLL-PELLVFSSKTDFHDHFLYKAGHIILQDKASCLPAYLLKPPSGSHVIDACAAPGNKTSHLAAIMKNKGK------LFAFDLDAKRLATMSTLL--------LRAGVTCQ-QLAHQDFLKVNPDSPQYKDVEYVLLDPSCSGSGMVCLQDR-------SSADQTRLASLAAFQLRCLNHAVRFPRLKRLVYSTCSIHSQENEEVITAFLQQ-NSSFRLVPLLPQ-WPERGLAPLSQCLRASTSKTRTHGFFVALLEKHSEALSS 420
[Close]
BLAST of SMED30023422 vs. Ensembl Medaka
Match: ENSORLT00000015205.3 (NOP2 nucleolar protein [Source:NCBI gene;Acc:101172522])

HSP 1 Score: 58.151 bits (139), Expect = 1.773e-8
Identity = 86/340 (25.29%), Postives = 137/340 (40.29%), Query Frame = -3 
Query:  306 EDKSIDLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSF----PNVKRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIWTDSWMTRGKKLFKQCIRTSPSYDLC----------NGFFVACFDRIRDHLPS 1283
            E   I  P+ +R N L   ++   +  +N G N           +   +W K                L+++++S  +       A   ++Q  +S +P   L P     V+D  +APG KTT++  ++           + A D +  R KS+   +        +T TV  N     F KV            + LD  CSG+G++ +    A + S +  D   L S H  + ++LS   S     P+   VVY TCS+T EENE VV+  ++K     +L P   D +   G   FKQ  R  PS  L           +GFFVA   +  + +P+
Sbjct:  324 EANEIQRPVTIRTNTLKTRRRDLAQALINRGVNL----------DPIGKWSKV--------------GLVIYDSSVPVGATPEYLAGHYMLQGASSFLPVMALSPQEGEMVLDMSSAPGGKTTYIAQLMRNTG------VIVANDANSERLKSVVGNIHRL----GVTNTVVCNYDGRQFPKV------MGGFDRVLLDAPCSGTGVIAK--DPAVKTSKDEADI--LRSAHLQKELILSAIDSVNAESPSGGYVVYCTCSITVEENEWVVDYALKK--RNVKLVPTGLD-FGKEGFTNFKQ-FRFHPSLKLTRRFYPHSHNMDGFFVAKLKKFSNVVPT 615
[Close]
BLAST of SMED30023422 vs. Planmine SMEST
Match: SMESG000042985.1 (SMESG000042985.1)

HSP 1 Score: 68.1662 bits (165), Expect = 9.095e-12
Identity = 81/328 (24.70%), Postives = 136/328 (41.46%), Query Frame = -3 
Query:  303 DLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNV-KRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIW-TDSWMTRGKKLFKQCI----RTSPSYDLCNGFFVACFDRIRDHLPSD 1268
            D P+ +R N L   ++A  E  +    N              +E L+  K G           ++VF+    +       A   ++Q  +S +P   L P     ++D CAAPG KT+H+  I++          +FA D ++ R K++ S LS       +  TV +        K      +  N   +  D  C+G+G++ +     +++     D++ L  L   Q  LL  A+    V   VVYSTCS+  EENE V++    K   +   + ++    +M    K F Q +    R  P  +  +GFF+A   +I DH P +
Sbjct:  251 DRPMTIRTNTLKTRRRALKEALIKRDCN--------------VETLQFSKVG-----------MVVFSAKCAIGATPEYLAGHYILQGSSSMLPVMALAPKKGERILDLCAAPGGKTSHIAQIMANTG------IIFANDINKDRLKAVTSNLSRM----GVMNTVVICNDGRSIHK------KVKNFNRVLCDAPCTGTGVISK-----DKSIKASKDEEDLKILTCIQKQLLCSAIDACKVGGYVVYSTCSILVEENEQVIDYACRKRNVKISETGLFGIKGFMNFRAKHFNQNMDRTRRYYPHENNMDGFFLAKLQKIGDHKPEN 532
[Close]
BLAST of SMED30023422 vs. Planmine SMEST
Match: SMESG000007627.1 (SMESG000007627.1)

HSP 1 Score: 68.1662 bits (165), Expect = 9.838e-12
Identity = 81/328 (24.70%), Postives = 136/328 (41.46%), Query Frame = -3 
Query:  303 DLPIYVRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFMPDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMDVIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALSTYRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQVDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNV-KRVVYSTCSXXXXXXXXXXXXXXEKFGTEFQLSPIW-TDSWMTRGKKLFKQCI----RTSPSYDLCNGFFVACFDRIRDHLPSD 1268
            D P+ +R N L   ++A  E  +    N              +E L+  K G           ++VF+    +       A   ++Q  +S +P   L P     ++D CAAPG KT+H+  I++          +FA D ++ R K++ S LS       +  TV +        K      +  N   +  D  C+G+G++ +     +++     D++ L  L   Q  LL  A+    V   VVYSTCS+  EENE V++    K   +   + ++    +M    K F Q +    R  P  +  +GFF+A   +I DH P +
Sbjct:  251 DRPMTIRTNTLKTRRRALKEALIKRDCN--------------VETLQFSKVG-----------MVVFSAKCAIGATPEYLAGHYILQGSSSMLPVMALAPKKGERILDLCAAPGGKTSHIAQIMANTG------IIFANDINKDRLKAVTSNLSRM----GVMNTVVICNDGRSIHK------KVKNFNRVLCDAPCTGTGVISK-----DKSIKASKDEEDLKILTCIQKQLLCSAIDACKVGGYVVYSTCSILVEENEQVIDYACRKRNVKISETGLFGIKGFMNFRAKHFNQNMDRTRRYYPHENNMDGFFLAKLQKIGDHKPEN 532
The following BLAST results are available for this feature:
BLAST of SMED30023422 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NSUN52.613e-5533.86NOP2/Sun RNA methyltransferase 5 [Source:HGNC Symb... [more]
NSUN53.138e-5533.86NOP2/Sun RNA methyltransferase 5 [Source:HGNC Symb... [more]
NSUN53.804e-5533.86NOP2/Sun RNA methyltransferase 5 [Source:HGNC Symb... [more]
NSUN55.132e-5536.27NOP2/Sun RNA methyltransferase 5 [Source:HGNC Symb... [more]
NOP21.174e-723.08NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of SMED30023422 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nsun-51.341e-4930.06Nop2 (NOP2)/SUN domain family member [Source:UniP... [more]
nsun-51.341e-4930.06Nop2 (NOP2)/SUN domain family member [Source:UniP... [more]
nsun-54.125e-4634.46Nop2 (NOP2)/SUN domain family member [Source:UniP... [more]
nsun-58.869e-4334.27Nop2 (NOP2)/SUN domain family member [Source:UniP... [more]
nol-21.053e-1224.71NucleOLar protein [Source:UniProtKB/TrEMBL;Acc:A0... [more]
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BLAST of SMED30023422 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Nsun55.222e-3328.72gene:FBgn0259704 transcript:FBtr0299957[more]
CG85457.798e-1125.00gene:FBgn0033741 transcript:FBtr0087934[more]
CG111091.094e-929.80gene:FBgn0037200 transcript:FBtr0078553[more]
CG111091.211e-929.80gene:FBgn0037200 transcript:FBtr0078552[more]
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BLAST of SMED30023422 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
nsun56.746e-5633.82NOP2/Sun RNA methyltransferase 5 [Source:ZFIN;Acc:... [more]
nsun58.145e-5138.18NOP2/Sun RNA methyltransferase 5 [Source:ZFIN;Acc:... [more]
nop21.308e-623.89NOP2 nucleolar protein homolog (yeast) [Source:ZFI... [more]
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BLAST of SMED30023422 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mpp61.076e-5433.68membrane protein, palmitoylated 6 [Source:Xenbase;... [more]
dapk35.312e-924.17death-associated protein kinase 3 [Source:Xenbase;... [more]
dapk38.881e-924.17death-associated protein kinase 3 [Source:Xenbase;... [more]
dapk39.788e-924.17death-associated protein kinase 3 [Source:Xenbase;... [more]
ENSXETT00000038204.11.799e-623.24NOP2 nucleolar protein [Source:NCBI gene;Acc:10049... [more]
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BLAST of SMED30023422 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Nsun52.630e-5333.48NOL1/NOP2/Sun domain family, member 5 [Source:MGI ... [more]
Nop25.474e-824.26NOP2 nucleolar protein [Source:MGI Symbol;Acc:MGI:... [more]
Nsun66.344e-628.90NOL1/NOP2/Sun domain family member 6 [Source:MGI S... [more]
Nsun66.344e-628.90NOL1/NOP2/Sun domain family member 6 [Source:MGI S... [more]
Nsun66.344e-628.90NOL1/NOP2/Sun domain family member 6 [Source:MGI S... [more]
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BLAST of SMED30023422 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q96P11|NSUN5_HUMAN1.507e-5433.86Probable 28S rRNA (cytosine-C(5))-methyltransferas... [more]
sp|Q8K4F6|NSUN5_MOUSE1.839e-5233.48Probable 28S rRNA (cytosine-C(5))-methyltransferas... [more]
sp|O14039|RCM1_SCHPO3.364e-4033.3325S rRNA (cytosine-C(5))-methyltransferase rcm1 OS... [more]
sp|Q63ZY6|NSN5C_HUMAN9.227e-3637.50Putative methyltransferase NSUN5C OS=Homo sapiens ... [more]
sp|Q8GYE8|NSUN5_ARATH1.991e-3430.4325S rRNA (cytosine-C(5))-methyltransferase NSUN5 O... [more]
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BLAST of SMED30023422 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Z2CXK11.596e-7135.60Putative 28S rRNA (Cytosine-C(5))-methyltransferas... [more]
H2KQ683.772e-7034.83Putative methyltransferase NSUN5 OS=Clonorchis sin... [more]
C7TXW04.604e-7035.21Putative methyltransferase NSUN5 OS=Schistosoma ja... [more]
A0A4S2M9501.351e-6933.89SAM_MT_RSMB_NOP domain-containing protein OS=Opist... [more]
A0A1S8WPU73.318e-6834.16NOL1/NOP2/sun family protein OS=Opisthorchis viver... [more]
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BLAST of SMED30023422 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nsun51.693e-6237.38NOP2/Sun RNA methyltransferase 5 [Source:ZFIN;Acc:... [more]
nop21.339e-724.34NOP2 nucleolar protein [Source:NCBI gene;Acc:10302... [more]
nop21.409e-724.34NOP2 nucleolar protein [Source:NCBI gene;Acc:10302... [more]
nop21.445e-724.34NOP2 nucleolar protein [Source:NCBI gene;Acc:10302... [more]
ENSAMXT00000034509.17.306e-623.79pep primary_assembly:Astyanax_mexicanus-2.0:2:3299... [more]
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BLAST of SMED30023422 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nop24.611e-823.24NOP2 nucleolar protein homolog (yeast) [Source:ZFI... [more]
nop23.175e-720.61NOP2 nucleolar protein homolog (yeast) [Source:ZFI... [more]
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BLAST of SMED30023422 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
RCM15.632e-3130.69rRNA m5C methyltransferase; methylates cytosine at... [more]
NOP26.673e-1125.97rRNA m5C methyltransferase; methylates cytosine at... [more]
NCL11.672e-827.27S-adenosyl-L-methionine-dependent tRNA: m5C-methyl... [more]
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BLAST of SMED30023422 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO453801.592e-6033.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO408951.130e-923.37Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO420709.345e-928.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO316513.382e-824.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO392481.601e-728.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMED30023422 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nsun51.818e-5633.76NOP2/Sun RNA methyltransferase 5 [Source:NCBI gene... [more]
ENSORLT00000015205.31.773e-825.29NOP2 nucleolar protein [Source:NCBI gene;Acc:10117... [more]
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BLAST of SMED30023422 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000042985.19.095e-1224.70SMESG000042985.1[more]
SMESG000007627.19.838e-1224.70SMESG000007627.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023422 ID=SMED30023422|Name=SMED30023422|organism=Schmidtea mediterranea sexual|type=transcript|length=1783bp
GAAAAAATTTATTCAGTTTTTATCCTTTTCTTATCTTTATTTGCATCAGC
CGCAGGTTTTTCTGCTTTGCGTTTTTTCTTTTTACCAGCCTCATCTACTT
TCTTTTCTTGGGGTTCCTGATTGATCGATTTCTCATTCTGCTTTTTAAGC
TGTTGCTCTTTTGCTTTCTTGCCGGTTTTTTTGGTCTTCCTCCTTTTTGG
ATAAGCCTTTTTGGTAACTTCAGTCTCGTTGCCTTGCGGCTGATGCTTGA
CGGGCTTGTGCTTAATGAATGATCCGGTATGGAGTTTTGGTTTCGGTTTG
TTATCCGATGGCAAGTGATCGCGGATCCGATCAAAACAGGCGACAAAGAA
GCCATTGCAAAGATCATAACTCGGGCTTGTGCGGATGCATTGCTTGAAAA
GCTTCTTACCACGAGTCATCCAACTGTCGGTCCAGATTGGGCTCAACTGG
AACTCGGTGCCGAATTTCTCTACAATCTCCTCCACGACCGCCTCGTTCTC
CTCATGGGTCACAGAGCAAGTCGAGTAAACGACCCTTTTGACATTCGGGA
ACGAGAGGGCGTGGCTGAGTAGCATGGCCTGGAAATTGTGAAGGGATGTC
AGCCGCTGCTGGTCGACCCGATTGTTACTGTTGCGCTCGGCCATCCTGTC
CACTTGACGCATGATTCCAGAACCTGAGCAGCTGGGATCCAGGCAGATAT
AACCGACGTTCGCGTAGCGTGGATCAGTCGGATCAACTTTTGTGAAGTCC
TCCAATTGGGTGTTGACGGTGACGGTTTGGGTTATCGCGTGGGGGCTGCG
GTAGGTCGACAGTGCGCTTTCGAGGCTCTTAAATCGGATCTCGTCTCGGT
CGAAAGCGAAAAGAGAAATCGGACTCTCCGGTTTATTTTTCTGGGACAAA
ATGGACAACAAATGAGTTGTTTTGTTGCCAGGGGCGGCACAAGCATCTAT
GACGTCCATGTCAGTATCTGGGTCAAGCACCGCGGCCGGTATGCAGCTAG
CTTTGTCCTGGATGAGCACCTTGCGAGCACGTACCAATTTGTCTGTGTGC
AGTACCGCCGAATTGTTGAACACCAACAGTTCCTCGTGCAAATGGTAATC
TGGCATAAAATCACCTTCTTTCAATTCTTTCAACCATTCAAGAAACTGAT
TGTATTTTACTGATTTATCCTCGTAATCGAGAAAATTGTATCCAGCATTC
ACGAAATGCTCAATCGCAGCTTTTTTTGTAATCAAAAGCAAATTGATTCT
TACGTAAATTGGTAAATCTATGCTTTTATCTTCTGGACGAAAATGATTCA
ATATTTCTTCTTTCGTTTTCAATTTGTTTTCACTAATCAATTCATCGAGA
ATCGTTTTAAAAACCTTCATTTTACTAATCAACGGACATCCCGACGTGTT
TGACGTGGCTTGACCAAATAGCATGTCGTAAATTTGAACTTTAATTCGAC
AATTTTCACAGCCAGTCCCGCTTTCGCATTCTCTAGAACTCTTTTTGCTT
TCAATTTTACCTAATTTCGATCTTTGAAAAATCTCATTGACGATTGCCTT
ATTTTTTATGGCTTCAGCCACAATAGCCAATAATTTCTTTAAATCACTAC
TAAAATGAGATTGAAAAAGGCCGTTTTTTAAATTGCAAACACCTGCTGCT
ACTTTACAATACAAAAGTCCTGCTTCTTTATATAAATTAATTTCTGAAGG
CATTACAGTGGTTTAGATTTAGCTCTTAAAGAATATTAAAACAATTTTAT
TAAATTGCTTTAAAATATAACGTTAGTTTTTTG
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protein sequence of SMED30023422-orf-1

>SMED30023422-orf-1 ID=SMED30023422-orf-1|Name=SMED30023422-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=565bp
MPSEINLYKEAGLLYCKVAAGVCNLKNGLFQSHFSSDLKKLLAIVAEAIK
NKAIVNEIFQRSKLGKIESKKSSRECESGTGCENCRIKVQIYDMLFGQAT
SNTSGCPLISKMKVFKTILDELISENKLKTKEEILNHFRPEDKSIDLPIY
VRINLLLITKKAAIEHFVNAGYNFLDYEDKSVKYNQFLEWLKELKEGDFM
PDYHLHEELLVFNNSAVLHTDKLVRARKVLIQDKASCIPAAVLDPDTDMD
VIDACAAPGNKTTHLLSILSQKNKPESPISLFAFDRDEIRFKSLESALST
YRSPHAITQTVTVNTQLEDFTKVDPTDPRYANVGYICLDPSCSGSGIMRQ
VDRMAERNSNNRVDQQRLTSLHNFQAMLLSHALSFPNVKRVVYSTCSVTH
EENEAVVEEIVEKFGTEFQLSPIWTDSWMTRGKKLFKQCIRTSPSYDLCN
GFFVACFDRIRDHLPSDNKPKPKLHTGSFIKHKPVKHQPQGNETEVTKKA
YPKRRKTKKTGKKAKEQQLKKQNEKSINQEPQEKKVDEAGKKKKRKAEKP
AADANKDKKRIKTE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR023267RCMT
IPR001678MeTrfase_RsmB/NOP2
IPR029063SAM-dependent_MTases
Vocabulary: molecular function
TermDefinition
GO:0008168methyltransferase activity