Calcium-activated chloride channel regulator 1

Overview
NameCalcium-activated chloride channel regulator 1
Smed IDSMED30023396
Length (bp)2935
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Calcium-activated chloride channel regulator 1 (SMED30023396) t-SNE clustered cells

Violin plots show distribution of expression levels for Calcium-activated chloride channel regulator 1 (SMED30023396) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Calcium-activated chloride channel regulator 1 (SMED30023396) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Calcium-activated chloride channel regulator 1 (SMED30023396) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023396

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30023396h1SMcG0003474 Contig21985uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023396h1SMcG0003474 Contig21985newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023396h1SMcG0003474 Contig20236newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023396h1SMcG0003474 Contig20236uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
cephalic gangliaSMED30023396h1SMcG0003474 dd_Smed_v4_696_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30023396h1SMcG0003474 dd_Smed_v4_696_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023396h1SMcG0003474 dd_Smed_v4_696_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pigment cellSMED30023396h1SMcG0003474 dd_Smed_v6_696_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023396h1SMcG0003474 dd_Smed_v6_696_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
glial cellSMED30023396h1SMcG0003474 dd_Smed_v6_696_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Human
Match: CLCA4 (chloride channel accessory 4 [Source:HGNC Symbol;Acc:HGNC:2018])

HSP 1 Score: 120.168 bits (300), Expect = 6.521e-27
Identity = 112/447 (25.06%), Postives = 195/447 (43.62%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFK-IVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSV----------------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSMN--EFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSY 1443
            ++ VI I   + + D K+IE I+  +  AS  L++AT      +    F  + I +P  W+   Q    K  +  H   IV        D+P+TKQ+ +CG+ G+Y  F+ +    K  NE      GK  + E+  LR+GVF E       +   +  +    C+  I  +  N   KC   + +                C++  D  Q    SIMF     +   FCN+K   HN  A +L NI C  +S   VI   +DF       +    P F +L    R + LVLD+SGSM   +  +++      F+ +  E  + + +V ++    IV+ L ++ +++ R  L   +      G S I  GIK    ++ E +++   D   ++L+TD +         S  I  +K+S  I+H ++    ++  + +++K + GS+
Sbjct:   32 EDIVIVIDPSVPE-DEKIIEQIEDMVTTASTYLFEAT------EKRFFFKNVSILIPENWKENPQYKRPKHENHKHADVIVAPPTLPGRDEPYTKQFTECGEKGEYIHFTPDLLLGKKQNEYG--PPGKLFVHEWAHLRWGVFDEYNEDQPFYRAKSKKIEATRCSAGISGR--NRVYKCQGGSCLSRACRIDSTTKLYGKDCQFFPDKVQTEKASIMFMQSIDSVVEFCNEKT--HNQEAPSLQNIKCNFRSTWEVISNSEDFKNTIPMVTPPPPPVFSLLKISQRIVCLVLDKSGSMGGKDRLNRMNQAAKHFLLQTVENGSWVGMVHFDSTATIVNKLIQIKSSDERNTLMAGLPTYPLGGTS-ICSGIKYAFQVIGELHSQL--DGSEVLLLTDGE-----DNTASSCIDEVKQSGAIVHFIALGRAADEAVIEMSKITGGSH 457
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Human
Match: CLCA1 (chloride channel accessory 1 [Source:HGNC Symbol;Acc:HGNC:2015])

HSP 1 Score: 116.701 bits (291), Expect = 7.658e-26
Identity = 107/442 (24.21%), Postives = 191/442 (43.21%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQ-VSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNN----FSLIKGICNQNIQWKVNNSP---EKCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSM--NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  V+ I   + + D  LI+ IK  + QAS  L +AT           F  + I +P  W+T+   V PK  T K    +V       +D+P+T+Q   CG+ G+    + +F   K L E     +G+  + E+  LR+GVF E       ++ N          GI   N+  K        ++C+           C++ +   Q    SIMF     +   FC +++  HN  A N  N  C  +S   VI   +DF K +   +    PTF +L    R + LVLD+SGSM      +++      F+ +  E  + + +VT++   ++ + L ++++ + R  L  ++      G S I  G+++   ++ +   K   D   ++L+TD      +    S     +K+S  I+H ++    +   L +L+K + G
Sbjct:   33 EGIVVAIDPNVPE-DETLIQQIKDMVTQASLYLLEATGKR------FYFKNVAILIPETWKTKADYVRPKLETYKNADVLVAESTPPGNDEPYTEQMGNCGEKGERIHLTPDFIAGKKLAEYG--PQGRAFVHEWAHLRWGVFDEYNNDEKFYLSNGRIQAVRCSAGITGTNVVKKCQGGSCYTKRCTFNKVTGLYEKGCEFVLQSRQTEKASIMFAQHVDSIVEFCTEQN--HNKEAPNKQNQKCNLRSTWEVIRDSEDFKKTTPMTTQPPNPTFSLLQIGQRIVCLVLDKSGSMATGNRLNRLNQAGQLFLLQTVELGSWVGMVTFDSAAHVQNELIQINSGSDRDTLAKRLPAAASGGTS-ICSGLRSAFTVIRK---KYPTDGSEIVLLTD-----GEDNTISGCFNEVKQSGAIIHTVALGPSAAQELEELSKMTGG 454
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Human
Match: CLCA1 (chloride channel accessory 1 [Source:HGNC Symbol;Acc:HGNC:2015])

HSP 1 Score: 116.701 bits (291), Expect = 7.658e-26
Identity = 107/442 (24.21%), Postives = 191/442 (43.21%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQ-VSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNN----FSLIKGICNQNIQWKVNNSP---EKCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSM--NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  V+ I   + + D  LI+ IK  + QAS  L +AT           F  + I +P  W+T+   V PK  T K    +V       +D+P+T+Q   CG+ G+    + +F   K L E     +G+  + E+  LR+GVF E       ++ N          GI   N+  K        ++C+           C++ +   Q    SIMF     +   FC +++  HN  A N  N  C  +S   VI   +DF K +   +    PTF +L    R + LVLD+SGSM      +++      F+ +  E  + + +VT++   ++ + L ++++ + R  L  ++      G S I  G+++   ++ +   K   D   ++L+TD      +    S     +K+S  I+H ++    +   L +L+K + G
Sbjct:   33 EGIVVAIDPNVPE-DETLIQQIKDMVTQASLYLLEATGKR------FYFKNVAILIPETWKTKADYVRPKLETYKNADVLVAESTPPGNDEPYTEQMGNCGEKGERIHLTPDFIAGKKLAEYG--PQGRAFVHEWAHLRWGVFDEYNNDEKFYLSNGRIQAVRCSAGITGTNVVKKCQGGSCYTKRCTFNKVTGLYEKGCEFVLQSRQTEKASIMFAQHVDSIVEFCTEQN--HNKEAPNKQNQKCNLRSTWEVIRDSEDFKKTTPMTTQPPNPTFSLLQIGQRIVCLVLDKSGSMATGNRLNRLNQAGQLFLLQTVELGSWVGMVTFDSAAHVQNELIQINSGSDRDTLAKRLPAAASGGTS-ICSGLRSAFTVIRK---KYPTDGSEIVLLTD-----GEDNTISGCFNEVKQSGAIIHTVALGPSAAQELEELSKMTGG 454
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Human
Match: CLCA2 (chloride channel accessory 2 [Source:HGNC Symbol;Acc:HGNC:2016])

HSP 1 Score: 99.7525 bits (247), Expect = 1.185e-20
Identity = 117/481 (24.32%), Postives = 204/481 (42.41%), Query Frame = 1 
Query:   67 RGIFSIYC-LNLVFSQIYCQTQEVFLDSERNIQN-----FVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSV--------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKI---PTFQILLRRGRQIVLVLDRSGSMNEFADK---VKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSK----IGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            R I    C L  V   +   ++  FL +   +Q+      +I I+ ++ + ++ LI NIK  + +AS  L+ AT         + F  I I +P  W+       K+ + +    IV      + D P+T QY  CGK GKY  F+  F    +L       +G+  + E+  LR+GVF E       +++    +    C+ +I          C  EN +        C +  +  QN   SIMF     +   FCN     HN  A NL N  C  +S   VI    DF+  S   +  ++   PTF ++    + + LVLD S  M E AD+   ++     ++ +  E    + I +++ +  I + L ++++ + RK L   V  +     +K    I  G+K G  ++ + N K    +  MIL+T    S D K    + +  +  S   +H ++  + +   L +L++ + G
Sbjct:    4 RSIAGPICNLKFVTLLVALSSELPFLGAGVQLQDNGYNGLLIAINPQVPE-NQNLISNIKEMITEASFYLFNATKRR------VFFRNIKILIPATWKANNNSKIKQESYEKANVIVTDWYGAHGDDPYTLQYRGCGKEGKYIHFTPNFLLNDNLTAGYG-SRGRVFVHEWAHLRWGVFDEYNNDKPFYINGQNQIKVTRCSSDITGIFVCEKGPCPQENCIISKLFKEGCTFIYNSTQNATASIMFMQSLSSVVEFCNAST--HNQEAPNLQNQMCSLRSAWDVITDSADFH-HSFPMNGTELPPPPTFSLVQAGDKVVCLVLDVSSKMAE-ADRLLQLQQAAEFYLMQIVEIHTFVGIASFDSKGEIRAQLHQINSNDDRKLL---VSYLPTTVSAKTDISICSGLKKGFEVVEKLNGKAYGSV--MILVT----SGDDKL-LGNCLPTVLSSGSTIHSIALGSSAAPNLEELSRLTGG 462
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Zebrafish
Match: clca1 (chloride channel accessory 1 [Source:ZFIN;Acc:ZDB-GENE-030131-6221])

HSP 1 Score: 139.428 bits (350), Expect = 3.479e-33
Identity = 122/460 (26.52%), Postives = 220/460 (47.83%), Query Frame = 1 
Query:  163 NFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFKI-------VPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQ---WKVNNSP-EKCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSA------KFSSYKIPTFQILLRRGRQIVLVLDRSGSM-NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFF--GLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSYQRLSGNV 1464
            +  I IS K+ + D KLI+ IK  + + S  LYKA   LDK    + F ++ I VP  W +      K FT KA  ++       +   +    D+P+T QY +CG  G+Y  F+  F  +  L       +GK ++ E+  LR+GV+ E   K   +   +  +    C++NI+   + V   P + C ++         C++  +  Q+ + S+M      +   FC + +  HN+ A NL N  C  K+  +VI   +D   K A        S+   P F+++ R  R + LVLD SGSM      +++     F++   E+ + +++VT++ + + +S LT +D  +TR++L   VK++     G + + KG+  G+ +L  +N     D   +I +TD + +       S+ + A   S  I+H ++  +K++  LR++A  + G +   S +V
Sbjct:   35 DITIAISSKVPE-DDKLIDKIKDMVTEGSVHLYKA---LDKK---VYFKEVTILVPLNWNS------KGFT-KARTELFETGMIRIDNPHPAYGDEPYTNQYGECGAEGQYIHFTPNFLRDDKLIRLYG-SRGKVLVHEWAHLRWGVYDEYSEKTPFYRSASGKIEATRCSKNIEGQLYDVTADPLQPCQNDPQTSLPTDGCRFIPNKYQSTDSSMMSLPSLDSVITFCRESE--HNYEAPNLQNAKCSNKATWTVIF--EDSVDKDALRSLKPMASTPPAPNFKVVQRMQRTVCLVLDVSGSMKGSRILRLQQASAHFLQNIIEDQSSVALVTFSTDASTLSALTTIDKESTRENL---VKLLPNVAEGATNMCKGLNLGLQVLKTDNQDVLGD--EIIFLTDGEATD----TLSNCVPAAINSGAIIHTIALGDKADKALREMADKTGGKFITASDDV 466
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Zebrafish
Match: clca1 (chloride channel accessory 1 [Source:ZFIN;Acc:ZDB-GENE-030131-6221])

HSP 1 Score: 133.265 bits (334), Expect = 2.766e-31
Identity = 118/446 (26.46%), Postives = 208/446 (46.64%), Query Frame = 1 
Query:  163 NFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFF-NEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKV----NNSPEKCSD------ENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPT-----FQILLRRGRQIVLVLDRSGSMNEFAD--KVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSY 1443
            +  I I  K+ K D  LI+ IK  +   S  LY A   LDK    +      I VP+ W  +     +  + +KA  KI    +     +P TK Y +CGK G+Y  F+ +F  N+ ++       +GK  + E+  LR+GV+ E   +   ++ N   +    C  NI+ ++      SP+ C         +S CK+  + +QN + S+MF         FC + +  HN+ A    NI C  K+  +VI +    +K +  F      T     F++L R+ R + L+LD SGSM   +   +++      ++ Y EE A + IV ++   +IVS LT +++  TR HL + +      G + +  G++ G+ +L E++     D   +I +TD Q + D      D I     S  I+H ++ ++ +++ L+++A  + G +
Sbjct:   30 DITIAIGAKV-KQDDTLIDKIKEMVTDGSFYLYHA---LDKK---VYLKDATILVPSHWSCKSCSKARTESFEKAKIKI----DHAKLMEPRTKLYGECGKGGEYIHFTPDFLLNDSAIQMYG--PRGKVFLHEWAHLRWGVYDEYNEEKPFYLSNG-RVEYTRCTTNIEGQIFEVNGGSPQSCRINPETFLPSSDCKFFPNKDQNTDSSVMFSPSLEAVTTFCRETE--HNYEAETQQNIICNNKATWTVIFE-DSVDKDALSFLPPLPSTPSPPIFKLLQRKKRAVCLILDVSGSMATESRILRMRQAATHLLRNYVEEQASVGIVKFSTAASIVSSLTIIESDATRDHLINLLPETP-GGSTNMCNGLRLGLQVLSEDDMDAIGD--EIIFLTDGQATDDVTLCIPDAIN----SGAIIHTIALSDSAHNALQEMADKTGGIF 451
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Zebrafish
Match: clca1 (chloride channel accessory 1 [Source:ZFIN;Acc:ZDB-GENE-030131-6221])

HSP 1 Score: 89.7373 bits (221), Expect = 8.646e-18
Identity = 73/291 (25.09%), Postives = 142/291 (48.80%), Query Frame = 1 
Query:  649 CNQNIQ---WKVNNSP-EKCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSA------KFSSYKIPTFQILLRRGRQIVLVLDRSGSM-NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFF--GLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSYQRLSGNV 1464
            C++NI+   + V   P + C ++         C++  +  Q+ + S+M      +   FC + +  HN+ A NL N  C  K+  +VI   +D   K A        S+   P F+++ R  R + LVLD SGSM      +++     F++   E+ + +++VT++ + + +S LT +D  +TR++L   VK++     G + + KG+  G+ +L  +N     D   +I +TD + +       S+ + A   S  I+H ++  +K++  LR++A  + G +   S +V
Sbjct:   13 CSKNIEGQLYDVTADPLQPCQNDPQTSLPTDGCRFIPNKYQSTDSSMMSLPSLDSVITFCRESE--HNYEAPNLQNAKCSNKATWTVIF--EDSVDKDALRSLKPMASTPPAPNFKVVQRMQRTVCLVLDVSGSMKGSRILRLQQASAHFLQNIIEDQSSVALVTFSTDASTLSALTTIDKESTRENL---VKLLPNVAEGATNMCKGLNLGLQVLKTDNQDVLGD--EIIFLTDGEATD----TLSNCVPAAINSGAIIHTIALGDKADKALREMADKTGGKFITASDDV 290
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Zebrafish
Match: clca1 (chloride channel accessory 1 [Source:ZFIN;Acc:ZDB-GENE-030131-6221])

HSP 1 Score: 86.6557 bits (213), Expect = 5.010e-17
Identity = 63/233 (27.04%), Postives = 118/233 (50.64%), Query Frame = 1 
Query:  793 FCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSA------KFSSYKIPTFQILLRRGRQIVLVLDRSGSM-NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFF--GLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSYQRLSGNV 1464
            FC + +  HN+ A NL N  C  K+  +VI   +D   K A        S+   P F+++ R  R + LVLD SGSM      +++     F++   E+ + +++VT++ + + +S LT +D  +TR++L   VK++     G + + KG+  G+ +L  +N     D   +I +TD + +       S+ + A   S  I+H ++  +K++  LR++A  + G +   S +V
Sbjct:    9 FCRESE--HNYEAPNLQNAKCSNKATWTVIF--EDSVDKDALRSLKPMASTPPAPNFKVVQRMQRTVCLVLDVSGSMKGSRILRLQQASAHFLQNIIEDQSSVALVTFSTDASTLSALTTIDKESTRENL---VKLLPNVAEGATNMCKGLNLGLQVLKTDNQDVLGD--EIIFLTDGEATD----TLSNCVPAAINSGAIIHTIALGDKADKALREMADKTGGKFITASDDV 228
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Zebrafish
Match: clca5.1 (chloride channel accessory 5, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-141216-62])

HSP 1 Score: 58.5362 bits (140), Expect = 2.970e-8
Identity = 37/140 (26.43%), Postives = 75/140 (53.57%), Query Frame = 1 
Query: 1045 FIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSYQRLSGNV 1464
            FI+   E+ + + IVT+N + +++S LT +DN +TR +L + +   K  G + + KG+  G+ +L  ++     D   +I +TD + + +  Y     + A   S  I+H ++  +K++  LR++A  + G +   S +V
Sbjct:    9 FIRNIIEDQSSVGIVTFNTDASLLSTLTTIDNESTRVNLVNLLPK-KTEGWTYMCKGLNLGLKVLKMDDQGVLGD--EIIFLTDGEATDNISY----CVPAAINSGAIIHTIALGDKADKALREMADKTGGKFITASDDV 141
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Xenopus
Match: ENSXETT00000038434.1 (chloride channel accessory 1 gene 2 [Source:NCBI gene;Acc:100490932])

HSP 1 Score: 132.494 bits (332), Expect = 6.940e-31
Identity = 124/474 (26.16%), Postives = 210/474 (44.30%), Query Frame = 1 
Query:   79 SIYCLNLVFSQIYCQTQEVFLDSERNI-------QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNI---------QWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKF-SSYKIPTFQILLRRGRQIVLVLDRSGSMNEFA--DKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQT-MILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            S++ L L F+        VFL S  +I       ++ VI I++ + + + K+I+NI+  +++AS+ L+ AT N       +    + I +P  W        K  T DKA   I+   + K  D P+T QY +CG+ GKY   + +F    +L       +G+  + E+  LR+GVF E  Y+   ++  N ++    C+ +I             N  P+    E+  C +  + NQ    SIM+     +   FC   D+ HN  A  L N  C  +S   VIM   D      +  S+  +PTF +L    R + LVLD SGSM       ++      F+ +  EE + + IV+++    ++S L +V +   R HL   +      G + I  GI+ G+ +   NN    +   T ++L+TD + + +    + DI      S II+H ++     N  L  +   + G
Sbjct:    5 SLFALVLTFN--------VFLVSGTSIKLQNGGYEDIVIAINQGLGE-NVKIIDNIQNMIKEASQYLFSATKNR------VYIRSVKILIPITWPNNNYAKAKTETYDKADV-IIASPHLKFGDDPYTLQYGRCGEAGKYIHMTPDFLLNDNLISIYG-PRGRVFVHEWAHLRWGVFDEYNYEKPFYIAGNKNIEATRCSADIIGTHIKQPQGQPCNRDPQTGLYEDG-CVFVPEQNQAAKASIMYLQALPSVTEFC---DKNHNTEAPTLQNRICNSRSTWDVIMNSTDIKATPPQADSNLPVPTFTLLQSSDRVVTLVLDVSGSMASDGRIGRLYQAAEVFVMQIVEEGSHVGIVSFSTSTTVLSKLVQVIDDTQRNHLKFLLPKTAVGG-TNICAGIREGIKV---NNQHDGSSYGTEIVLLTDGEDNYNTSLCFPDI----SNSGIIVHFIALGPNPNPNLETIVDMTGG 449
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Xenopus
Match: ENSXETT00000026373.1 (chloride channel accessory 1 gene 2 [Source:NCBI gene;Acc:100490932])

HSP 1 Score: 132.494 bits (332), Expect = 7.873e-31
Identity = 124/474 (26.16%), Postives = 210/474 (44.30%), Query Frame = 1 
Query:   79 SIYCLNLVFSQIYCQTQEVFLDSERNI-------QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNI---------QWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKF-SSYKIPTFQILLRRGRQIVLVLDRSGSMNEFA--DKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQT-MILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            S++ L L F+        VFL S  +I       ++ VI I++ + + + K+I+NI+  +++AS+ L+ AT N       +    + I +P  W        K  T DKA   I+   + K  D P+T QY +CG+ GKY   + +F    +L       +G+  + E+  LR+GVF E  Y+   ++  N ++    C+ +I             N  P+    E+  C +  + NQ    SIM+     +   FC   D+ HN  A  L N  C  +S   VIM   D      +  S+  +PTF +L    R + LVLD SGSM       ++      F+ +  EE + + IV+++    ++S L +V +   R HL   +      G + I  GI+ G+ +   NN    +   T ++L+TD + + +    + DI      S II+H ++     N  L  +   + G
Sbjct:    5 SLFALVLTFN--------VFLVSGTSIKLQNGGYEDIVIAINQGLGE-NVKIIDNIQNMIKEASQYLFSATKNR------VYIRSVKILIPITWPNNNYAKAKTETYDKADV-IIASPHLKFGDDPYTLQYGRCGEAGKYIHMTPDFLLNDNLISIYG-PRGRVFVHEWAHLRWGVFDEYNYEKPFYIAGNKNIEATRCSADIIGTHIKQPQGQPCNRDPQTGLYEDG-CVFVPEQNQAAKASIMYLQALPSVTEFC---DKNHNTEAPTLQNRICNSRSTWDVIMNSTDIKATPPQADSNLPVPTFTLLQSSDRVVTLVLDVSGSMASDGRIGRLYQAAEVFVMQIVEEGSHVGIVSFSTSTTVLSKLVQVIDDTQRNHLKFLLPKTAVGG-TNICAGIREGIKV---NNQHDGSSYGTEIVLLTDGEDNYNTSLCFPDI----SNSGIIVHFIALGPNPNPNLETIVDMTGG 449
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Xenopus
Match: ENSXETT00000038492.1 (chloride channel accessory 4 gene 1 [Source:NCBI gene;Acc:100488301])

HSP 1 Score: 123.635 bits (309), Expect = 5.117e-28
Identity = 125/474 (26.37%), Postives = 216/474 (45.57%), Query Frame = 1 
Query:   73 IFSIYCLNLVFSQIYCQTQEVFLD-SERNIQNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVS-PKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFF-NEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWK-----VNNSPEKCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFS-SYKIPTFQILLRRGRQIVLVLDRSGSM---NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            ++S++ L L+ S + C T    +  +    ++ VI I   +++ D K+IEN++  +++A++ L+ AT    K +  IK  KI I  P +W        PK  T DKA   I+   + K  D P+T QY +CG+PG+Y   + +F  N+K +++     +G+  + E+  LR+GVF E  Y    ++  N  +    C+ +I+           P  CS +         C +  +  Q+   SIM+     +   FC+ K   HN  A  L N  C+ +S   VI    D      +   +  +P+F +L    R + LVLD SGSM   N    +++ V   F+ +  E  A + IV ++   ++VS L +++    R  L   +      G + I  GI+ G  I L  N    +    ++L+TD + + D    + DI      S  I+HV++    +   L  +A  + G
Sbjct:    3 LWSLFPLALIAS-LCCSTWASMIKLNGGGYEDIVIAIHPNVTEND-KIIENVQNMVKEANQYLFNAT----KQRLFIKSAKILI--PFKWSKHNNADKPKTETYDKADV-IIAEPHLKYGDDPYTLQYGRCGEPGRYIHLTPDFLVNDKMISQYG--PRGRVFVHEWAHLRWGVFDEYNYDKPFYIAANGDVEATRCSADIKGTYTKRNCQGKPCNCSPDPKTGLYEDDCVFVPETYQSVKESIMYLQALPSVSEFCDSK---HNTEAPTLQNRMCESRSTWDVISNSTDIKSTVPRADFNIPVPSFSLLQFSERVVSLVLDVSGSMSSSNRIGRQLQAVEL-FVVQIIENGAHVGIVKFSSSASVVSSLVKINTQAQRDQLKSLIPRTAGGG-TNICAGIRAG--IALNKNFDGSSYGTEIVLLTDGEDNLDTSLCFKDITD----SGAIIHVIALGPNAAKELETIANMTGG 454
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Xenopus
Match: gnl3 (guanine nucleotide binding protein-like 3 (nucleolar) [Source:Xenbase;Acc:XB-GENE-6456133])

HSP 1 Score: 119.783 bits (299), Expect = 7.074e-27
Identity = 112/440 (25.45%), Postives = 192/440 (43.64%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNI-----------QWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKF-SSYKIPTFQILLRRGRQIVLVLDRSGSMNEFA--DKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            ++ VI I+  + + + K+IENI+  +  AS  L+ AT N    +  IK  KI I  P  W  +     +  T      I+   + K  D P+T QY  CG+ GKY   + +F     L       +G+  + E+  LR+GVF E  Y+   ++  + ++    C+ +I             K    P+    E+  C +  + N     SIM+     +   FC   D+ HN  A  L N  C  +S   VIM   D      +  S+  +P+F +L    R + LVLD SGSM      +++      F+ +  EE + + I+T++  ++++S L +V     RK L   +     FG + I  GI+ G+ I  + +  +      ++L+TD + + D    + DI      S  I+HV++    +   L  +   + G
Sbjct:   31 EDIVIAINPGL-RENVKIIENIQNMINGASHYLFNATRN----RVYIKSVKILI--PMTWSNKSYTKARTETYNKADVIIATPHLKFGDDPYTLQYGGCGEAGKYIHMTPDFLLNDVLVSVYG-PRGRVFVHEWAHLRWGVFDEYNYEKPFYITGDKNIEATRCSADITGTYIKPCQGQTCKCIRDPQTGLYEDD-CVFVPERNGAAKASIMYLQALPSVTEFC---DKNHNTEAPTLQNRICNSRSTWDVIMNSTDIKSTPPQADSNIPVPSFSLLQSSDRVVTLVLDVSGSMASGGRIERLYQAAEVFLMQIVEEGSYVGILTFSTSISLLSNLVQVIENTQRKQLKSLLPT-NAFGGTDICLGIREGIKINRQYDGSSYG--TELVLLTDGEDNYDTSKCFPDI----TNSGAIIHVIALGPNAAKALETIVDMTEG 451
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Xenopus
Match: csnk2a2 (casein kinase 2 alpha 2 [Source:Xenbase;Acc:XB-GENE-487069])

HSP 1 Score: 115.546 bits (288), Expect = 1.342e-25
Identity = 112/429 (26.11%), Postives = 184/429 (42.89%), Query Frame = 1 
Query:  208 KLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSL--KKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNI-----------QWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSS--YKIPTFQILLRRGRQIVLVLDRSGSMNEF--ADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQT-MILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            K+I+NI+  + +AS+ L+ AT    K++  I+  KI I  P  W        +  T DKA   I+   + K  D P+T QY +CG+PGKY   + +F     LN+  S    +G+  + E+  LR+GVF E  Y+   ++  N ++    C+ +I             K    P+    E+  C +  D NQ    SIM+     +   FC   D+ HN  A  L N  C  +S   VIM   D      +  S    +P+F +L    R + LVLD SGSM       ++      F+ +  E  + + IV +    ++ S L ++ +   R  L   +      G + I  GI+ G+ +   N     +   T ++L+TD +      Y  S     +  S  I+HV++    +   L  +   + G
Sbjct:   47 KIIDNIQNMITEASQYLFSAT----KNRVYIRNAKILI--PMAWSNNKYTKARTETYDKADV-IIASSHVKFGDDPYTLQYGRCGEPGKYIHMTPDFL----LNDLISTYGPRGRAFVHEWAHLRWGVFDEYNYEKPFYIAGNKNIEATRCSADIIGTHIKQCQGKTCKCARDPQTGLYEDG-CVFVPDKNQVPKASIMYLQALQSVTEFC---DKNHNTEAPTLQNRICNSRSTWDVIMNSTDIKSTPPQADSNIPAVPSFSLLQSSERVVTLVLDVSGSMGGGNRIGRLYQAAEVFVMQIVEMGSYVGIVQFESTASVRSSLLQIVDDTQRNRLKSLLPKTATGG-TNICAGIREGIKV---NKKYDGSSYSTELVLLTDGE----DNYATSLCFPDVTNSGSIIHVIALGPNAAKELETIVDMTGG 452
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Mouse
Match: Clca3a1 (chloride channel accessory 3A1 [Source:MGI Symbol;Acc:MGI:1316732])

HSP 1 Score: 120.939 bits (302), Expect = 2.212e-27
Identity = 112/448 (25.00%), Postives = 202/448 (45.09%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQ-VSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSV----------------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSA--KFSSYKIPTFQILLRRGRQIVLVLDRSGSMN--EFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  VI I+  + + D +LI +IK  + QAS  L++A      SQ  + F  I I VP  W+++ + + PK+ + DKA   IV   + ++ D P+T QY +CG  G+Y  F+  F    +L  +    +G+  + E+  LR+GVF E       ++    ++    C+  I     N    C   N V                C +  D  Q    SIMF  + ++   FC +K+  HN  A NL N  C  +S   VI    DF          +   PTF +L  R R + LVLD+SGSM+  +   ++      ++ +  E+ + + +VT++   +I + L ++ +++  + +   +   +  G + I  G++ G   +  ++  T      ++L+TD +   D   +     +A+ RS  I+H ++    +   L  L+  + G
Sbjct:   32 EGVVIAINPSVPE-DERLIPSIKEMVTQASTYLFEA------SQGRVYFRNISILVPMTWKSKPEYLMPKRESYDKADV-IVADPHLQHGDDPYTLQYGQCGDRGQYIHFTPNFLLTDNL--RIYGPRGRVFVHEWAHLRWGVFDEYNVDQPFYMSRKNTIEATRCSTRI--TGTNVVHNCERGNCVTRACRRDSKTRLYEPKCTFIPDKIQTAGASIMFMQNLNSVVEFCTEKN--HNAEAPNLQNKMCNRRSTWDVIKTSADFQNAPPMRGTEAPPPPTFSLLKSRRRVVCLVLDKSGSMDKEDRLIRMNQAAELYLTQIVEKESMVGLVTFDSAAHIQNYLIKITSSSDYQKITANLPQ-QASGGTSICHGLQAGFQAITSSDQSTSG--SEIVLLTDGE---DNGIR--SCFEAVSRSGAIIHTIALGPSAARELETLSDMTGG 457
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Mouse
Match: Clca3a1 (chloride channel accessory 3A1 [Source:MGI Symbol;Acc:MGI:1316732])

HSP 1 Score: 118.627 bits (296), Expect = 2.376e-27
Identity = 112/448 (25.00%), Postives = 202/448 (45.09%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQ-VSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSV----------------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSA--KFSSYKIPTFQILLRRGRQIVLVLDRSGSMN--EFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  VI I+  + + D +LI +IK  + QAS  L++A      SQ  + F  I I VP  W+++ + + PK+ + DKA   IV   + ++ D P+T QY +CG  G+Y  F+  F    +L  +    +G+  + E+  LR+GVF E       ++    ++    C+  I     N    C   N V                C +  D  Q    SIMF  + ++   FC +K+  HN  A NL N  C  +S   VI    DF          +   PTF +L  R R + LVLD+SGSM+  +   ++      ++ +  E+ + + +VT++   +I + L ++ +++  + +   +   +  G + I  G++ G   +  ++  T      ++L+TD +   D   +     +A+ RS  I+H ++    +   L  L+  + G
Sbjct:   32 EGVVIAINPSVPE-DERLIPSIKEMVTQASTYLFEA------SQGRVYFRNISILVPMTWKSKPEYLMPKRESYDKADV-IVADPHLQHGDDPYTLQYGQCGDRGQYIHFTPNFLLTDNL--RIYGPRGRVFVHEWAHLRWGVFDEYNVDQPFYMSRKNTIEATRCSTRITG--TNVVHNCERGNCVTRACRRDSKTRLYEPKCTFIPDKIQTAGASIMFMQNLNSVVEFCTEKN--HNAEAPNLQNKMCNRRSTWDVIKTSADFQNAPPMRGTEAPPPPTFSLLKSRRRVVCLVLDKSGSMDKEDRLIRMNQAAELYLTQIVEKESMVGLVTFDSAAHIQNYLIKITSSSDYQKITANLPQ-QASGGTSICHGLQAGFQAITSSDQSTSGS--EIVLLTDGE---DNGIR--SCFEAVSRSGAIIHTIALGPSAARELETLSDMTVG 457
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Mouse
Match: Clca3a2 (chloride channel accessory 3A2 [Source:MGI Symbol;Acc:MGI:1931471])

HSP 1 Score: 119.013 bits (297), Expect = 9.087e-27
Identity = 110/448 (24.55%), Postives = 202/448 (45.09%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQ-VSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSV----------------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSA--KFSSYKIPTFQILLRRGRQIVLVLDRSGSMN--EFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  VI I+  + + D +LI +IK  + QAS  L++A      SQ  + F  I I VP  W+++ + + PK+ + DKA   IV   + ++ D P+T QY +CG  G+Y  F+  F    +L  +    +G+  + E+  LR+GVF E       ++    ++    C+ +I  K      +C   + V                C +  D  Q    SIMF  + ++   FC + +  HN  A NL N  C  +S   VI    DF          +   PTF +L  R R + LVLD+SGSM+  +   ++      ++ +  E+ + + +VT++   +I + L ++ +++  + +   +   +  G + I  G++ G   +  ++  T      ++L+TD      +    S   +A+ RS  I+H ++    +   L  L+  + G
Sbjct:   32 EGVVIAINPSVPE-DERLIPSIKEMVTQASTYLFEA------SQGRVYFRNISILVPMTWKSKSEYLMPKRESYDKADV-IVADPHLQHGDDPYTLQYGQCGDRGQYIHFTPNFLLTDNL--RIYGPRGRVFVHEWAHLRWGVFDEYNVDRPFYISRKNTIEATRCSASITGK--KVVHECQRGSCVTRACRRDSKTRLYEPKCTFIPDKIQTAGASIMFMQNLNSVVEFCTENN--HNAEAPNLQNKMCNRRSTWDVIKASADFQNSPPMRGTEAPPPPTFSLLKSRRRVVCLVLDKSGSMDKEDRLIRMNQAAELYLTQIVEKESMVGLVTFDSAAHIQNYLIKITSSSDYQKITANLPQ-QATGGTSICHGLQAGFQAITSSDQSTSGS--EIVLLTD-----GEDNGISSCFEAVSRSGAIIHTIALGPSAARELETLSDMTGG 457
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Mouse
Match: Clca1 (chloride channel accessory 1 [Source:MGI Symbol;Acc:MGI:1346342])

HSP 1 Score: 118.627 bits (296), Expect = 1.383e-26
Identity = 111/451 (24.61%), Postives = 199/451 (44.12%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVS-PKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKG-----ICNQNIQWKVNNSPEKCSDENSV-----------------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSM--NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  VI I   + + D  LI++IK  + QAS  L++AT           F  + I +P  W+ + + + PK  T K    +V   +   +D+P+T+    CG+ G     + +F   K L +     + +  + E+   R+GVF+E  Y N       F L KG      C+  I  K  N   +C   + +                 C +  D +QN   SIMF+ + ++   FC +K+  HN  A N  N  C  +S   VI + +DF + +   +    PTF +L    R + LVLD+SGSM  ++  +++      F+ +  E+ + + +VT++    + S L ++++   R  L   +  +   G S I  G++T   ++     K   D   ++L+TD      +    S     +K+S  I+H ++    +   L +L+K + G
Sbjct:   33 EGIVIAIDHDVPE-DEALIQHIKDMVTQASPYLFEATGKR------FYFKNVAILIPESWKAKPEYTRPKLETFKNADVLVSTTSPLGNDEPYTEHIGACGEKGIRIHLTPDFLAGKKLTQYG--PQDRTFVHEWAHFRWGVFNE--YNN----DEKFYLSKGKPQAVRCSAAITGK--NQVRRCQGGSCITNGKCVIDRVTGLYKDNCVFVPDPHQNEKASIMFNQNINSVVEFCTEKN--HNQEAPNDQNQRCNLRSTWEVIQESEDFKQTTPMTAQPPAPTFSLLQIGQRIVCLVLDKSGSMLNDDRLNRMNQASRLFLLQTVEQGSWVGMVTFDSAAYVQSELKQLNSGADRDLLIKHLPTVSAGGTS-ICSGLRTAFTVI---KKKYPTDGSEIVLLTD-----GEDNTISSCFDLVKQSGAIIHTVALGPAAAKELEQLSKMTGG 455
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Mouse
Match: Clca3b (chloride channel accessory 3B [Source:MGI Symbol;Acc:MGI:2181989])

HSP 1 Score: 116.701 bits (291), Expect = 5.317e-26
Identity = 116/451 (25.72%), Postives = 204/451 (45.23%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQ-VSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSE----RPY----KNVLFVHNNFSLIKGI-----CNQN--IQWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFS--SYKIPTFQILLRRGRQIVLVLDRSGSMNEFADKVKDVVCK-----FIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFF-GLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  VI I+  + + D +LI +IK  + QAS  L++AT           F  + I VP  W+++ + ++PK+ + D+A   IV   + ++ D P+T QY +CG  G+Y  F+  F    +L       +G+  + E+  LR+GVF E    RP+    KN +      + I G      C     +  +      K   + + C +  + +Q    SIMF     +   FC +K   HN  A NL N  C  +S   VI    DF   S      +  +PTF +L  R R + LVLD+SGSM   +   +  +       ++ +  E+ + + +VT++    I + L R+ N ++  +L    K+ ++  G + I  G+K G   +  ++  T      ++L+TD + +R      S   + +K S  I+H ++    +   L  L+  + G
Sbjct:   32 EGVVIAINPSVPE-DERLIPSIKEMVTQASTYLFEATERR------FYFRNVSILVPITWKSKTEYLTPKQESYDQADV-IVADPHLQHGDDPYTLQYGQCGDRGQYIHFTPNFLLTDNLGIYG--PRGRVFVHEWAHLRWGVFDEYNMDRPFYMSRKNTVEATRCSTDITGTSVVRECQGGSCVSRRCRRD-AKTGMQEAKCTFIPNKSQTARGSIMFMQSLDSVVEFCTEKT--HNVEAPNLQNKMCNLRSTWDVIKASADFQNASPMTGTEAPPLPTFSLLKSRQRVVCLVLDKSGSMRLGSPITRLTLMNQAAELYLIQIIEKESLVGLVTFDSTATIQTNLIRIINDSS--YLAISTKLPQYPNGGTSICNGLKKGFEAITSSDQSTSGS--EIVLLTDGEDNR-----ISSCFQEVKHSGAIIHTIALGPSAARELETLSDMTGG 460
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. UniProt/SwissProt
Match: sp|P54281|CLCA1_BOVIN (Calcium-activated chloride channel regulator 1 OS=Bos taurus OX=9913 PE=1 SV=1)

HSP 1 Score: 136.346 bits (342), Expect = 2.546e-31
Identity = 116/447 (25.95%), Postives = 208/447 (46.53%), Query Frame = 1 
Query:  163 NFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQ-VSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSV----------------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKS--AKFSSYKIPTFQILLRRGRQIVLVLDRSGSMN--EFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
              VI I+  + + D KLI+NIK  + +AS  L+ AT         + F  + I +P  W+++ + + PK+ + D+A   IV     K+ D P+T QY +CG+ G+Y  F+  F    +L    S  +G+  + E+  LR+G+F E       ++    ++    C+ +I     N   KC   + +                C +  + +Q    SIMF    H+   FC +K   HN  A NL N  C GKS   VIM   DF   S   + +    PTF +L  + R + LVLD+SGSM+  +   ++      F+ +  E+ + + +VT++    I + LT++ + N  +++   +   +  G + I +G+K G   ++++   T      +IL+TD      +  +    I+ +K+S +I+H ++    +   L  L+  + G
Sbjct:   33 GIVIAINPSVPE-DEKLIQNIKEMVTEASTYLFHATKRR------VYFRNVSILIPMTWKSKSEYLMPKQESYDQAEV-IVANPYLKHGDDPYTLQYGRCGEKGQYIHFTPNFLLTNNLPIYGS--RGRAFVHEWAHLRWGIFDEYNGDQPFYISRRNTIEATRCSTHITG--TNVIVKCQGGSCITRPCRRDSQTGLYEAKCTFIPEKSQTARESIMFMQSLHSVTEFCTEKT--HNVEAPNLQNKMCNGKSTWDVIMNSTDFQNTSPMTEMNPPTQPTFSLLKSKQRVVCLVLDKSGSMSSEDRLFRMNQAAELFLIQIIEKGSLVGMVTFDSVAEIRNNLTKITDDNVYENITANLPQ-EANGGTSICRGLKAGFQAIIQSQQSTSGS--EIILLTD-----GEDNEIHSCIEEVKQSGVIIHTIALGPSAAKELETLSDMTGG 457
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. UniProt/SwissProt
Match: sp|Q2TU62|CLCA1_HORSE (Calcium-activated chloride channel regulator 1 OS=Equus caballus OX=9796 GN=CLCA1 PE=1 SV=1)

HSP 1 Score: 134.806 bits (338), Expect = 8.430e-31
Identity = 117/445 (26.29%), Postives = 205/445 (46.07%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVS-PKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGI-CNQNIQWK--VNN------SPEKCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSMNEFADKVKDVVCK---FIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  VI I   + + D  LI+ IK  + QAS  L++AT           F  + I VP  W+T+ +   PK  T K    +V   N   +D+P+T+Q  KCG+ G+   F+ +F   K L+E     +G+  + E+  LR+G+F+E       ++ N    IK + C+ +I  K  VN+      + + C  +         C++  D  Q    SIMF     +   FC +++  HN  A N+ N  C  +S   VI   +DF K +   +    PTF +L    R + LVLD+SGSM    D++K +      F+ +  E+ + + +VT++    + S L ++     R  L   +  +   G S I  G+++   ++ +   K + D   ++L+TD      +    S     +K+S  I+H ++    + + L +L+K + G
Sbjct:   33 EGIVIAIDPNVPE-DETLIQQIKDMVTQASPYLFEATEKR------FYFKNVAILVPENWKTKPEYERPKLETYKNADVLVAEPNPPGNDQPYTEQMGKCGEKGERIYFTPDFLAGKRLDEYG--PQGRVFVHEWAHLRWGLFNEYNDDQKFYLSNK--EIKPVKCSADIAGKNVVNHCQGGSCATKPCRRDRVTGLYAQECEFIPDEQQTEKASIMFSQSIDSVVEFCTEEN--HNREAPNMQNQRCNLRSTWEVIRDSEDFKKTTPMTAQPPQPTFSLLQIGQRIVCLVLDKSGSM-AIGDRLKRLTQAGKLFLLQTVEQGSWVGMVTFDSAAYVQSALRQIKGGTDRDALTKSLPTVASGGTS-ICSGLRSAFTVIRK---KYKTDGSEIVLLTD-----GEDNTISSCFNEVKQSGAIIHTVALGPSAAAELEELSKMTGG 454
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. UniProt/SwissProt
Match: sp|Q9TUB5|CLCA1_PIG (Calcium-activated chloride channel regulator 1 OS=Sus scrofa OX=9823 GN=CLCA1 PE=2 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 1.502e-26
Identity = 114/446 (25.56%), Postives = 197/446 (44.17%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQ-VSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVL-FVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSV----------------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSMNEFA--DKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  VI I   + + D +LI+NIK  + +AS  L++AT           F  + I +P  W+ + + V PK  T K    +V   N   +D P+T+Q   CG+ G+   F+ +F   K + +     +G+  + E+  LR+GVF+E  Y N   F  +N      IC+  I  +  N   +C   + V                C++  D  Q+   SIMF     T   FC +K+  HN  A N  N  C  +S   VI   +DF K +   +    PTF +L    R + LVLD+SGSM       ++      F+ +  E+ A + +V ++    + S L ++++A  R  L   +      G S I  G+++   ++     K   D   ++L+TD + +       S     +K++  I+H ++    +   L +L++ + G
Sbjct:   33 EGIVIAIDPNVPE-DERLIQNIKDMVTKASPYLFEATEKR------FYFKNVAILIPASWKAKPEYVKPKLETYKNADVVVTEPNPPENDGPYTEQMGNCGEKGEKIYFTPDFVAGKKVLQYG--PQGRVFVHEWAHLRWGVFNE--YNNEQKFYLSNKKEQPVICSAAI--RGTNVLPQCQGGSCVTKPCRADRVTGLFQKECEFIPDPQQSEKASIMFAQSIDTVVEFCKEKN--HNKEAPNDQNQKCNLRSTWEVIQDSEDFKKTTPMTTQPPAPTFSLLQIGQRIVCLVLDKSGSMTVGGRLKRLNQAGKLFLLQTVEQGAWVGMVAFDSAAYVKSELVQINSAAERDALARSLPTAASGGTS-ICSGLRSAFTVI---KKKYPTDGSEIVLLTDGEDN-----TISACFPEVKQNGAIIHTVALGPSAAKELEELSQMTGG 454
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. UniProt/SwissProt
Match: sp|Q9QX15|CA3A1_MOUSE (Calcium-activated chloride channel regulator 3A-1 OS=Mus musculus OX=10090 GN=Clca3a1 PE=1 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 1.547e-26
Identity = 112/448 (25.00%), Postives = 202/448 (45.09%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQ-VSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSV----------------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSA--KFSSYKIPTFQILLRRGRQIVLVLDRSGSMN--EFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  VI I+  + + D +LI +IK  + QAS  L++A      SQ  + F  I I VP  W+++ + + PK+ + DKA   IV   + ++ D P+T QY +CG  G+Y  F+  F    +L  +    +G+  + E+  LR+GVF E       ++    ++    C+  I     N    C   N V                C +  D  Q    SIMF  + ++   FC +K+  HN  A NL N  C  +S   VI    DF          +   PTF +L  R R + LVLD+SGSM+  +   ++      ++ +  E+ + + +VT++   +I + L ++ +++  + +   +   +  G + I  G++ G   +  ++  T      ++L+TD +   D   +     +A+ RS  I+H ++    +   L  L+  + G
Sbjct:   32 EGVVIAINPSVPE-DERLIPSIKEMVTQASTYLFEA------SQGRVYFRNISILVPMTWKSKPEYLMPKRESYDKADV-IVADPHLQHGDDPYTLQYGQCGDRGQYIHFTPNFLLTDNL--RIYGPRGRVFVHEWAHLRWGVFDEYNVDQPFYMSRKNTIEATRCSTRI--TGTNVVHNCERGNCVTRACRRDSKTRLYEPKCTFIPDKIQTAGASIMFMQNLNSVVEFCTEKN--HNAEAPNLQNKMCNRRSTWDVIKTSADFQNAPPMRGTEAPPPPTFSLLKSRRRVVCLVLDKSGSMDKEDRLIRMNQAAELYLTQIVEKESMVGLVTFDSAAHIQNYLIKITSSSDYQKITANLPQ-QASGGTSICHGLQAGFQAITSSDQSTSG--SEIVLLTDGE---DNGIR--SCFEAVSRSGAIIHTIALGPSAARELETLSDMTGG 457
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. UniProt/SwissProt
Match: sp|Q14CN2|CLCA4_HUMAN (Calcium-activated chloride channel regulator 4 OS=Homo sapiens OX=9606 GN=CLCA4 PE=1 SV=2)

HSP 1 Score: 120.168 bits (300), Expect = 3.132e-26
Identity = 112/447 (25.06%), Postives = 195/447 (43.62%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFK-IVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSV----------------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSMN--EFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSY 1443
            ++ VI I   + + D K+IE I+  +  AS  L++AT      +    F  + I +P  W+   Q    K  +  H   IV        D+P+TKQ+ +CG+ G+Y  F+ +    K  NE      GK  + E+  LR+GVF E       +   +  +    C+  I  +  N   KC   + +                C++  D  Q    SIMF     +   FCN+K   HN  A +L NI C  +S   VI   +DF       +    P F +L    R + LVLD+SGSM   +  +++      F+ +  E  + + +V ++    IV+ L ++ +++ R  L   +      G S I  GIK    ++ E +++   D   ++L+TD +         S  I  +K+S  I+H ++    ++  + +++K + GS+
Sbjct:   32 EDIVIVIDPSVPE-DEKIIEQIEDMVTTASTYLFEAT------EKRFFFKNVSILIPENWKENPQYKRPKHENHKHADVIVAPPTLPGRDEPYTKQFTECGEKGEYIHFTPDLLLGKKQNEYG--PPGKLFVHEWAHLRWGVFDEYNEDQPFYRAKSKKIEATRCSAGISGR--NRVYKCQGGSCLSRACRIDSTTKLYGKDCQFFPDKVQTEKASIMFMQSIDSVVEFCNEKT--HNQEAPSLQNIKCNFRSTWEVISNSEDFKNTIPMVTPPPPPVFSLLKISQRIVCLVLDKSGSMGGKDRLNRMNQAAKHFLLQTVENGSWVGMVHFDSTATIVNKLIQIKSSDERNTLMAGLPTYPLGGTS-ICSGIKYAFQVIGELHSQL--DGSEVLLLTDGE-----DNTASSCIDEVKQSGAIVHFIALGRAADEAVIEMSKITGGSH 457
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. TrEMBL
Match: A0A3N0YDY5 (Calcium-activated chloride channel regulator 3A-1 OS=Anabarilius grahami OX=495550 GN=DPX16_10272 PE=4 SV=1)

HSP 1 Score: 151.754 bits (382), Expect = 2.494e-33
Identity = 124/439 (28.25%), Postives = 224/439 (51.03%), Query Frame = 1 
Query:  163 NFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQT-EIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKV-NNSPEKC-SDENSV-----CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAK-----FSSYKIPTFQILLRRGRQIVLVLDRSGSM-NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFF-----GLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLA 1422
            +  I IS ++ + D  LI+ IK  + + S  L++A   LDK    + F +  I VP  W + E   +  +  +KA+ +I    N    D+P+T QY +CG   ++  F+  F  + +L  K    +GK ++ E+  LR+GV+ E    N  F ++N  +    C++NI+ +  + S + C +D  ++     CK+  +  QN + SIMF     +   FC++ +  HN+ A NL N  C GK+  +VI +    +K + +      SS  +PTF+++ R  R + LVLD SGSM      +++     F++   E+ A + IVT++ +   +SPLT +D+ +TR+      K+IK       G + I KG+  G+ +L ++N     D   +I +TD + + +     +  + A  +S  I+H ++  +K++  LR++A
Sbjct:  734 DVTIAISSRVPQ-DNTLIDKIKDMVTKGSIHLHQA---LDKK---VYFKEATILVPPHWNSKEFTKARAESYEKANIRI-DNANPAYGDEPYTLQYDECGAEAQFIHFTPNFLQDDTLI-KTYGSRGKVLVHEWAHLRWGVYDEYSETNP-FYYSNGHIEATRCSKNIEGQYYDESRQPCQTDPQTLLPTKGCKFFPNKYQNTDSSIMFLPSLDSVSTFCHENE--HNYEAPNLQNKKC-GKATRTVIFE-DSVDKDALRSLKPLLSSPPVPTFKVVQRMHRVVCLVLDVSGSMKGPRMRRLQQAATHFLQNIIEDQASVGIVTFSTDAKTLSPLTTIDSESTRE------KLIKLLPKVAEGWTYICKGLNLGLQVLTKDNGDVIGD--EIIFLTDGEATDN----INSCVPAAIKSGAIIHTIALGDKADKALREMA 1146
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. TrEMBL
Match: A0A267GPW8 (VWFA domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024505g1 PE=4 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 2.951e-33
Identity = 117/463 (25.27%), Postives = 219/463 (47.30%), Query Frame = 1 
Query:  124 TQEVFLDSERNIQNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTE-IQVSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVL----FVHNN-FSLIKGICNQNIQWKVN--NSPEKCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFC----NDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRG-RQIVLVLDRSGSM----NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNIL-LENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
             +++ LD+     + ++ +S+ I + D +L++ IK   +QAS+ L  A S ++ S+    FG ++I VP  W  + +  S    T D AHF++    +++ S  P T Q   CG+PG +     E   + S  +      GK+++ EF  LR+GVF+E  Y   L    F+H    S ++  C+ +I  K    ++   C  +         C++ +D  Q    S+M+ +   +   FC     D D  HN  A N  N  C G+SV SV+++H D+ K      +     F ++  RG R++V+V+D SGSM         K+K  V   +    E+  + ++ +++    ++  L  +D+A  R+     V  +   G + IG  +   M +L  + N  ++ D   ++L+TD Q +   +Y  +       R+ I++  ++F ++++  L +L+  + G
Sbjct:   23 ARDIVLDNNGRYNDVLVSVSQNIPE-DWELVQRIKDGFQQASQRLAVA-SRINGSR-SFAFGHVYILVPRSWSNQSVDSSATWHTEDAAHFRV----DQRGSQIPSTVQPGDCGQPGLHVNLHREHLRDTSAEDL-----GKQLVHEFAHLRWGVFNE--YNGALGPHAFLHQGRLSPVR--CSASITGKFGHKDTGNPCKVDRVTLELEPDCRFILDSAQTAQASLMYTTYLASVRQFCQPPSGDPDFDHNVAAPNPQNRRCYGRSVQSVMLEHADYKKAIDGSETDTTVNFTVVQPRGARRLVIVMDVSGSMGTNQGTPLAKMKIAVRTLLLGLLEDGIQCAMTSFSTSSTLLRNLNPLDSAAIRREYWRIVAGLTARGGTAIGGALADAMELLGADMNRPSKEDTGYILLLTDGQENHTPRYTLAQATAIAARTSIVVDTVAFGSQADKRLAELSAVTGG 469
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. TrEMBL
Match: T1II73 (VWFA domain-containing protein OS=Strigamia maritima OX=126957 PE=4 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 5.550e-33
Identity = 137/473 (28.96%), Postives = 217/473 (45.88%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQ----VSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLK-KGKRIMKEFVKLRYGVFSE---------RPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSVCKYTIDGNQNHN---YSIMFDSDSHTS----------DYFCNDKDR-PHNHLAYNLHNIFCKGKSVSSVIMKHQDF--NKKSAKFSSYKIPTFQILLRR---GRQIVLVLDRSGSM-NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG-----SYQRLSGN 1461
            +  VI I   +++ D ++I+N+K     AS++LYK T N         F  I I VP  W  +++    +   +F+  A F+ V + N+   + P+T Q   CGK G+Y   + EF  E   N   S    GK ++ E+   RYGVF E         RP+       NN       C++NI       P   +DE   C   IDG  N N   Y  M  +  H+S          + FC+D +   HN  A + HNI C GKS  +V+  H DF  +    + +    P F+IL  R   G   VLVLD SGSM  +    +     +FIK    + ++++IVT++     ++ LT V    TR+ L D++      G + IG+G+   + +L   + K   D   +ILI+D +   +     +D+I  + RS + ++ ++F N ++  L KL + + G     S   +SGN
Sbjct:   28 KGVVIAIHNSVAE-DHRIIDNLKELFTNASETLYKMTRNRSY------FDDIAIIVPANWSKQVEYVQTIGGNRFS-IADFR-VDQPNEMYGNVPYTLQADSCGKSGQYVHLTPEFVKELHGNTAKSFGDPGKTLIHEWAHYRYGVFDEYADKYDEKTRPF--YYDAENNIRATG--CSENI-------PGWLADEGQPCSLGIDGLPNENCEFYPDMNANGGHSSLMYMHFLPTMEGFCDDTEELQHNSAAPSKHNIMCGGKSTWNVVSNHPDFLNDNNPPRSNLNPKPKFRILQPRIEDGGYFVLVLDVSGSMSGQRIAMLHRAAARFIKTQVPDKSQLAIVTFSTVPKTLADLTLV-TPETREVLADRIPNKDDGGNTAIGQGLLLALEVL---SDKDATDGGVIILISDGE--ENVLPHIADVIPKILRSRVRINTIAFGNHASRHLEKLVRLTGGHGYFFSDDDISGN 474
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. TrEMBL
Match: A0A267GGI1 (VWFA domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024505g3 PE=4 SV=1)

HSP 1 Score: 148.288 bits (373), Expect = 1.424e-32
Identity = 118/463 (25.49%), Postives = 221/463 (47.73%), Query Frame = 1 
Query:  124 TQEVFLDSERNIQNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTE-IQVSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVL----FVHNN-FSLIKGICNQNIQWKVN--NSPEKCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFC----NDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRG-RQIVLVLDRSGSM--NEFAD--KVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNIL-LENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
             +++ LD+     + ++ +S+ I + D +L++ IK   +QAS+ L  A S ++ S+    FG ++I VP  W  + +  S    T D AHF++    +++ S  P T Q   CG+PG +     E   + S  +      GK+++ EF  LR+GVF+E  Y   L    F+H    S ++  C+ +I  K    ++   C  +         C++ +D  Q    S+M+ +   +   FC     D D  HN  A N  N  C G+SV SV+++H D+ K      +     F ++  RG R++V+V+D SGSM  N+ A   K+K  V   +    E+  + ++ +++    ++  L  +D+A  R+     V  +   G + IG  +   M +L  + N  ++ D   ++L+TD   +   +Y  +       R+ I++  ++F ++++  L +L+  + G
Sbjct:   23 ARDIVLDNNGRYNDVLVSVSQNIPE-DWELVQRIKDGFQQASQRLAVA-SRINGSR-SFAFGHVYILVPRSWSNQSVDSSATWHTEDAAHFRV----DQRGSQIPNTVQPGDCGQPGLHVNLHREHLRDTSAEDL-----GKQLVHEFAHLRWGVFNE--YNGALGPHAFLHQGRLSPVR--CSASITGKFGHKDTGNPCKVDRVTLELEPDCRFILDSAQTAQASLMYTTYLASVRQFCQPPSGDPDFDHNVAAPNPQNRRCYGRSVQSVMLEHADYKKAIDGSETDTTVNFTVVQPRGARRLVIVMDVSGSMGTNQGAPLAKMKIAVRTLLLGLLEDGIQCAMTSFSTSSTLLRDLDPLDSAAIRRDYWRIVAGLTARGSTAIGGALAAAMELLGADMNRPSKEDTGYILLLTDGIENHTPRYTLAQATAIAARTSIVVDTVAFGSQADKRLAELSAVTGG 469
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. TrEMBL
Match: A0A369S8L6 (Epithelial chloride channel protein OS=Trichoplax sp. H2 OX=287889 GN=TrispH2_005102 PE=4 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 4.164e-32
Identity = 127/472 (26.91%), Postives = 220/472 (46.61%), Query Frame = 1 
Query:   76 FSIY-CLNLVFSQIYCQTQEVFLDSERNIQNFVIQISEKISKYD-RKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEI--QVSPKKFTDKAHFKI--VPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYK--NVLFVHNNFSLIKGICNQNIQWKVNN--SPEKCS-DENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCN-DKDRP---HNHLAYNLHNIFCKGKSVSSVIMKHQDF--NKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSMNEF-ADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
             S+Y CL L+ S    Q++ +    E      V+ ISE I + D   L+ ++  S   AS  LY AT N         F  + I +P  WQ ++  Q +  +  D A F+I  VP   +       T   P CG  G+Y     + F      ++      + I+ E+   RYGVF E       + F+    ++ +  C   I+  + +  + +KC+    S C Y++   +    SIMFD +  + + FC+ D   P   HN  A N  N++C  +S  +VIM+HQDF  N   A+     +P  +I+ R+  + VLVLD SGSM      +++     FI   A E   + IV++N    I+S LT++ + N + +L  Q+      GL+ +G G+ + +N+L  +  ++      MI+++D +   +     S +I  L  ++II+H +S  + ++  L+ ++  + G
Sbjct:    9 LSVYACLILILSH---QSRCIVTIKENGYAGVVVAISENIVESDYPTLVSDLIQSFINASSYLYTATRNRAF------FKNVTILIPATWQDKVTYQAATSQSFDSADFRIDLVPGHTRAT-----TVGVPGCGMSGQYILIPPQRF------QQVKAPPYRMIVHEWAHYRYGVFDEYAVSPSQLGFIDGQGNINENKCTAQIEGGIIDIITGKKCNYPYGSNCVYSVTNGKGSKGSIMFDQNIDSVNTFCDTDNSNPLTYHNAFALNNQNLYCLFQSTWTVIMRHQDFTNNNNPARQIDITVPNIRIVRRKDIRTVLVLDTSGSMQGVRLQQMRLATTNFILNSAVEGEFLGIVSFNSRTTIMSSLTKIVDQNVKNNLIAQIPSAA-VGLTSVGGGLLSALNMLKSSVNQSFPCGGRMIVLSDGE--ENVGPYISSVINDLVSNQIIVHTVSLGSSASERLQNVSYSTGG 457
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Cavefish
Match: ENSAMXT00000007776.2 (calcium-activated chloride channel regulator 1 [Source:NCBI gene;Acc:103026350])

HSP 1 Score: 133.265 bits (334), Expect = 2.403e-31
Identity = 148/565 (26.19%), Postives = 256/565 (45.31%), Query Frame = 1 
Query:  163 NFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNN----FSLIKGICNQNIQWKVNNSPE-KCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVI----MKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSM-NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTR----KHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSY----QRLSGNVSLDNIFXXXXXXXXXXXXXXXIELFLKDKSYKYSYNATYQ-----ANVTTVNVNIEKNLRKYMVKMSNKSGLEILPKSTNLNPRDTQ-LVFEIKGQLKPGKYYLTFL 1767
            + +I I+  + + D +LI  IK  +   S+ L+ A    DK    + F ++ I VP  W+   + + ++  DKA    + R N    D+P+TKQ   CG+ G+Y  F+ +F  +  L +    ++ K  + E+  LR+GVF E   +   ++  N       IK I  +N  +KV N     C  + +       C++  D  Q ++ SIM+     +   FC   D  HN+ A N+ N  C  +S SSVI    +     N      S    PTF ++ R+ R I L+LD SGSM  E   +++     F+ E  EE A++ IV ++    IVSPLT +    +R    +HL   V      G + +  G+  G  +L +++  T+ D   +I +TD + +     K  D ++++  S  I++ ++    ++S L  +A  +NG +    Q L  N  +D       + +      + I+L    K+    +N T        N TT  V  EK++    V +   SG  +  ++   N ++T+ +   I G  +PG +  +FL
Sbjct:   30 DLLIAINPAVPQND-ELINQIKDMITSGSQYLFHAVE--DK----VFFKEVKILVPPTWKGNYERAKRETYDKASV-FIDRPNPIFGDEPYTKQMKGCGEEGEYIHFTPDFLLDDDLLDAYGTRE-KVFVHEWAHLRWGVFDEYSEEEPFYLFGNNIEPTRCIKDIRGRN--YKVTNGKHVHCPTDVATGLPIKGCQFFPDREQENSASIMYMQSLDSVKAFCGFMD--HNYEAPNMQNKKCDYRSTSSVIFGSSVDSDALNTLQPLPSPPPPPTFTVIQRQHRVICLILDVSGSMKGERILRLQQAATLFLSEIVEEGAQVGIVKFSTNAEIVSPLTTLQGKESRDGLIRHLPKTVD-----GSTNMCNGLNLGFEVLKKDDGSTKGD--DLIFLTDGEATD----KVEDCLQSVVDSGAIVNTIALGPSASSVLITMANLTNGKFIVADQSLLSNQLVDAF--TSFILSDGDPTKQAIQLVSIGKNTADWFNGTVPIDRTVGNGTTFTVIYEKSIPT--VHIEAPSG-RVYNQTHVTNHQETKTITLNIPGTAEPGDWKYSFL 565
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Cavefish
Match: ENSAMXT00000037970.1 (calcium-activated chloride channel regulator 1 [Source:NCBI gene;Acc:103026350])

HSP 1 Score: 127.872 bits (320), Expect = 1.077e-29
Identity = 136/518 (26.25%), Postives = 234/518 (45.17%), Query Frame = 1 
Query:  304 FGKIFISVPNQWQTEIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNN----FSLIKGICNQNIQWKVNNSPE-KCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVI----MKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSM-NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTR----KHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSY----QRLSGNVSLDNIFXXXXXXXXXXXXXXXIELFLKDKSYKYSYNATYQ-----ANVTTVNVNIEKNLRKYMVKMSNKSGLEILPKSTNLNPRDTQ-LVFEIKGQLKPGKYYLTFL 1767
            F ++ I VP  W+   + + ++  DKA    + R N    D+P+TKQ   CG+ G+Y  F+ +F  +  L +    ++ K  + E+  LR+GVF E   +   ++  N       IK I  +N  +KV N     C  + +       C++  D  Q ++ SIM+     +   FC   D  HN+ A N+ N  C  +S SSVI    +     N      S    PTF ++ R+ R I L+LD SGSM  E   +++     F+ E  EE A++ IV ++    IVSPLT +    +R    +HL   V      G + +  G+  G  +L +++  T+ D   +I +TD + +     K  D ++++  S  I++ ++    ++S L  +A  +NG +    Q L  N  +D       + +      + I+L    K+    +N T        N TT  V  EK++    V +   SG  +  ++   N ++T+ +   I G  +PG +  +FL
Sbjct:   19 FKEVKILVPPTWKGNYERAKRETYDKASV-FIDRPNPIFGDEPYTKQMKGCGEEGEYIHFTPDFLLDDDLLDAYGTRE-KVFVHEWAHLRWGVFDEYSEEEPFYLFGNNIEPTRCIKDIRGRN--YKVTNGKHVHCPTDVATGLPIKGCQFFPDREQENSASIMYMQSLDSVKAFCGFMD--HNYEAPNMQNKKCDYRSTSSVIFGSSVDSDALNTLQPLPSPPPPPTFTVIQRQHRVICLILDVSGSMKGERILRLQQAATLFLSEIVEEGAQVGIVKFSTNAEIVSPLTTLQGKESRDGLIRHLPKTVD-----GSTNMCNGLNLGFEVLKKDDGSTKGD--DLIFLTDGEATD----KVEDCLQSVVDSGAIVNTIALGPSASSVLITMANLTNGKFIVADQSLLSNQLVDAF--TSFILSDGDPTKQAIQLVSIGKNTADWFNGTVPIDRTVGNGTTFTVIYEKSIPT--VHIEAPSG-RVYNQTHVTNHQETKTITLNIPGTAEPGDWKYSFL 514
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Cavefish
Match: ENSAMXT00000007818.2 (pep primary_assembly:Astyanax_mexicanus-2.0:1:5630898:5645307:1 gene:ENSAMXG00000007608.2 transcript:ENSAMXT00000007818.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 116.701 bits (291), Expect = 5.007e-27
Identity = 118/440 (26.82%), Postives = 199/440 (45.23%), Query Frame = 1 
Query:  163 NFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFT-DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLK----KGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKV----NNSPEKCSDENSV------CKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKH----QDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSM-NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLA 1422
            + +I I+  + + D +LI  IK  + + S+ L +A   LD+    +   ++ I VP  W        ++ T DKA+  IV   N    D+P+TKQ   CG+ G++  F+ +F     L + D LK    + K  + E+  LR+GVF E   K   +   N  L    C+  I  K+    + SP  CS +         CK+  + +Q  + SIMF         FC D D  HN  A N  N  C  +S  ++I KH          +   +    P F+++ R+ R   L+LD SGSM  E   + +     F+ E  EE A ++IV ++ + +I SPLT++    +R  L   +      G + + KG+   + +L  ++  T  D   +I +TD + S +    +   +K    S  I++ L+    ++  L+ +A
Sbjct:   30 DLLIAINPAVPQND-ELINRIKTMITKGSEYLLEA---LDRK---VFIKEVNILVPPTWTGYSFTKARRETYDKANV-IVGHPNTAFGDEPYTKQMKGCGEEGEHIHFTPDF-----LLKDDLLKVFGPREKVFVHEWAHLRWGVFDEYNKKQPFYWSKNQQLEHTRCSGKIAGKLYDVSSGSPLPCSYDPKTGLPTKGCKFIPNKDQKTSSSIMFMPSLDAVKTFCEDGD--HNTEAPNRQNKECNFRSTRTIIYKHSVDSAALKTLTPLKTKPPPPKFRVVQRKSRATCLILDVSGSMSGERIRRQQQAAALFLSEIVEEGASVAIVQFSNDASIRSPLTKIKGKASRDALIKNLPT-SAGGGTYMCKGLLKSLEVLKADDGDTIGD--DVIFLTDGEASDNINTCFQTAVK----SGAIINTLALGPSASVILKTMA 447
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Cavefish
Match: ENSAMXT00000054901.1 (pep primary_assembly:Astyanax_mexicanus-2.0:1:5707968:5721043:-1 gene:ENSAMXG00000007580.2 transcript:ENSAMXT00000054901.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 82.8037 bits (203), Expect = 4.604e-16
Identity = 97/361 (26.87%), Postives = 152/361 (42.11%), Query Frame = 1 
Query:  163 NFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFIS-----VPNQWQTEIQVSPKKFTDKA-HFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFV----KLRYGVFSE-RPYKNVLFVHNNFSLIKGICNQNIQWK----VNNSPEKC------SDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPT------FQILLRRGRQIVLVLDRSGSM-NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHL 1161
            + +I I+  + + D +LI  IKI +   S+ L++A  N           K+FI      VP  W    + + ++  DK  HF  + R       +P+TKQ   CG+ G+Y   +  F  + S   K    +G+  +  +V    KL +  +S  RP++               C+  I  K    VN S   C      S     C++  D  Q  N SIM+     +   FC D++  HN  A N  N  C  +S  SVI KH   +  SA   +           F+ + RR R I L+LD SGSM      + +     F+ E  EE A + IV ++ + +I + LT++    +R  L
Sbjct:   30 DLLIAINPAVPQND-ELINRIKIMITDGSEYLHQALDN-----------KVFIKEVKILVPPNWNGSYEKARRETYDKVQHFNQILRL------RPYTKQMKGCGEEGEYVHLTPNFLLDDSF-LKSYGPRGETSVHVYVHVAQKLSWQHYSPTRPFQ---------------CSGRIAGKLVEVVNGSALPCYYDPKTSLPTEGCQFLPDKYQQTNASIMYIQSLDSVKTFCGDEE--HNTEAPNQQNKECNFRSTRSVIYKH---SVDSAALQTLTPVPSPSPPTFREVQRRNRVICLILDVSGSMAGGRILRQQQAATLFLSEIVEEGAYVGIVQFSNDASIRNHLTKIKGKASRDTL 351
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Cavefish
Match: ENSAMXT00000007808.2 (pep primary_assembly:Astyanax_mexicanus-2.0:1:5707968:5721043:-1 gene:ENSAMXG00000007580.2 transcript:ENSAMXT00000007808.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.9518 bits (193), Expect = 9.882e-15
Identity = 94/360 (26.11%), Postives = 145/360 (40.28%), Query Frame = 1 
Query:  163 NFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFIS-----VPNQWQTEIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNV-----LFVHNNFSLIKGICNQNIQWK----VNNSPEKC------SDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPT------FQILLRRGRQIVLVLDRSGSM-NEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHL 1161
            + +I I+  + + D +LI  IKI +   S+ L++A  N           K+FI      VP  W    + + ++  DK    +  R  +    +P+TKQ   CG+ G+Y   +  F  + S                F+K  YG   E     +     LF     +     C+  I  K    VN S   C      S     C++  D  Q  N SIM+     +   FC D++  HN  A N  N  C  +S  SVI KH   +  SA   +           F+ + RR R I L+LD SGSM      + +     F+ E  EE A + IV ++ + +I + LT++    +R  L
Sbjct:   30 DLLIAINPAVPQND-ELINRIKIMITDGSEYLHQALDN-----------KVFIKEVKILVPPNWNGSYEKARRETYDKYIHSL--RHGRILRLRPYTKQMKGCGEEGEYVHLTPNFLLDDS----------------FLK-SYGPRGETSVHGIDSHWNLFRDFRVNFCLCTCSGRIAGKLVEVVNGSALPCYYDPKTSLPTEGCQFLPDKYQQTNASIMYIQSLDSVKTFCGDEE--HNTEAPNQQNKECNFRSTRSVIYKH---SVDSAALQTLTPVPSPSPPTFREVQRRNRVICLILDVSGSMAGGRILRQQQAATLFLSEIVEEGAYVGIVQFSNDASIRNHLTKIKGKASRDTL 353
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Sea Lamprey
Match: CLCA1 (chloride channel accessory 1 [Source:HGNC Symbol;Acc:HGNC:2015])

HSP 1 Score: 132.109 bits (331), Expect = 1.174e-31
Identity = 117/451 (25.94%), Postives = 197/451 (43.68%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFT--DKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEF-FNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVH-NNFSLIK-----------------GICN-QNIQWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKI-PTFQILLRRGRQIVLVLDRSGSMNEFA--DKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  VI I+  + + D +LI+ IK  +  AS  L+KAT+ L        F  + I +P+ W ++   +  K+    KA  +I    + ++ D P+T+QY +CG+PG+Y + +  F   +K+L+      +G+  + E+  LR+G+F E       ++H NN    +                 G C  Q  +  +N  PE+       C +  D  Q    SIM        + FC      HN  A NL N  C   S   ++ KH+DFN      +     PTF +L    R I LVLD+SGSM+  +   +++     FI +  EE   + IVT++        LT + +  +R  L   +      G + I  G+  G  +L  ++     D   ++L+TD +         S   +A++ S   +H ++    +   L KLA+ S G
Sbjct:   37 EGLVIAINPAVPE-DPQLIDAIKDMVGDASAYLFKATNRL------AYFKHVSILIPSFWSSQSNYTRPKYESYGKAEVRIASLDDPED-DSPYTQQYGQCGEPGQYIQLTPNFLLADKNLDAY--CPRGRAFVHEWGHLRWGLFDEYNEDEPFYLHGNNVEFTRCSRGVTGGTGVVSCSSIGSCKVQACKIGINGLPEQG------CMFFPDKVQMARESIMALQWLDNVEEFCTVNS--HNRNAPNLQNRLCSSSSAWDIMQKHEDFNNNEPPPADVPTQPTFSLLRPSHRVITLVLDKSGSMSGGSRLQRLRQAADIFIMQILEEGEMVGIVTFDSSAQTKCGLTLITDTGSRVALKSCLPT-GAGGETNICAGVSKGFQVLSGDDGSASGD--EIVLMTDGE-----DGGISSCFEAVRTSGCTIHTIALGPSAVKELEKLAELSGG 461
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Sea Lamprey
Match: CLCA1 (chloride channel accessory 1 [Source:HGNC Symbol;Acc:HGNC:2015])

HSP 1 Score: 129.028 bits (323), Expect = 1.296e-30
Identity = 123/469 (26.23%), Postives = 204/469 (43.50%), Query Frame = 1 
Query:   97 LVFSQIYCQTQEVFLDSER------NIQNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPK-KFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFS----ERPY----KNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENS-----VCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSMNEFA--DKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            L+ + + C   E+  DS R        +  VI I+  + + D KLI+ IK  +  AS  L+ AT+        + F  + I +P+ W ++    P  ++  KA   + P  + ++ D P+T+QY +CG+PG+Y + +  F  +   N K    +G+  + E+   R+G+F     E P+    KN  F   +  +  GI   N +     + +KC  E++      C +  D  Q    SIM     ++ + FC  K   HN LA N  N  C   S   V++KH D N  S   S    PTF +L    R I LVLD+SGSM       ++      FI +  +E     IVT+         LT +  A +R+ L   +      G + I  G+  G  +L  ++     D   +IL+TD +         S   +A + S   +H ++    + + L   A+ ++G
Sbjct:   10 LILAAVLCSAVELS-DSSRVRLIGNGYEGLVIAINPTVPE-DPKLIDAIKGMVTDASAYLHAATNRR------VFFKNVSILIPSSWTSKNYTRPTYEYYGKADVLVHPWDDPED-DSPYTQQYGQCGEPGQYIQLTPNFLLDDK-NLKAYGPRGRAFVHEWGHFRWGLFDEYSEEEPFYVNGKNPEFTRCSRDITGGIGKVNCRVGGACTVDKCKIESTGLPEKGCSFFPDEVQTAKESIMGLQWINSVNTFCTAKT--HNRLAPNRQNRLCGLSSAWEVMLKHDDINNTSPA-SVPTQPTFTLLQPSARVITLVLDKSGSMGGAMRLPRLLQAAEIFIMQILQEGDTAGIVTFESGAQTQCRLTEI-TAASRETLKSCLPK-NAGGGTNICAGLTQGFQVLSADDGSASGD--EIILMTDGE-----DGGISSCFEAARGSGCTIHTIALGPSAVNGLDNFAELTDG 456
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Sea Lamprey
Match: CLCA1 (chloride channel accessory 1 [Source:HGNC Symbol;Acc:HGNC:2015])

HSP 1 Score: 114.005 bits (284), Expect = 5.295e-26
Identity = 106/442 (23.98%), Postives = 186/442 (42.08%), Query Frame = 1 
Query:  160 QNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQT-EIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSER----PY----KNVLFVHNNFSLIKG----ICNQNIQWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKS-AKFSSYKIPTFQILLRRGRQIVLVLDRSGSMNEF--ADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNG 1437
            +  VI I+  + + D +LI  IK  +  AS  L++AT         + F  + I +P  W+T  I   PK  +  A   ++  ++    + P+T Q+  CG+PG+Y   +  F       E     +GK  + E+  LR+G++ E     P+      + F   +  L  G    + N ++  +  N   K       C +  D  Q    SIM          FC+     HN  A  LHN  C  KS   ++ +H DF  K+     +   P+F +L    R + LVLD SGSMN      +++     FI +  +    I I+ +N + N    LT++ +  +R  + + + M    G + +  G++    +L   +     D   ++L+TD + S       S  +  ++ S+ I+H ++    ++  L KL     G
Sbjct:   34 EALVIAINPAVPE-DPQLINAIKDMITNASSDLFRATKYR------LYFRNVSILIPASWKTNSIYNRPKSESYGAADVLIVSRDDPTDNSPYTHQFGLCGEPGQYIHLTPNFLLTDHYLEAYG-PRGKVFVHEWGHLRWGLYDEYNDQVPFYLDKGKIEFTRCSKDLTGGHVMVMRNDSVSTRNCNIDPKTGLPEEGCTFFPDVVQTATSSIMSIQALDNVKEFCSVNQ--HNKAAPTLHNRLCASKSTWQIMQRHNDFKVKTKLPVGTDTQPSFTLLQPTARVVTLVLDVSGSMNGANRLQRMRQASENFIMKILDAGTLIGIIVFNSKANTNLALTKITDEASRVLIKNNLPM-NVNGGTNVCAGVRHAFQVLRALDGDVSGD--EIVLLTDGEDS-----GISSCVAEVQNSQCIVHTIALGPNADPALEKLTTAEGG 457
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Planmine SMEST
Match: SMESG000080919.1 (SMESG000080919.1)

HSP 1 Score: 1628.61 bits (4216), Expect = 0.000e+0
Identity = 833/835 (99.76%), Postives = 833/835 (99.76%), Query Frame = 1 
Query:   64 MRGIFSIYCLNLVFSQIYCQTQEVFLDSERNIQNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSMNEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSYQRLSGNVSLDNIFXXXXXXXXXXXXXXXIELFLKDKSYKYSYNATYQANVTTVNVNIEKNLRKYMVKMSNKSGLEILPKSTNLNPRDTQLVFEIKGQLKPGKYYLTFLKSEKKSKHHNNPKNAEKILKNIKFSIYAENKKSNQRRINPVGFISKTFFEEVDSKTFLTVTVDLSGCDITNEERANVILEINLPSDKKVFKILXXXXXXXXXXXXXXIYTVNIYPKDLLEKGFYNFIAQVEIINMKTTKEKIKRTVIFESLQVKDVKDSAWTDAISPAQMIQLKIKIIDRNRIQLKTFATGDDSMEGQINRYQIIVRSKEDKTFDVLKSAKPYEEIFFDLDLWDLDNMSSMEVAVRGIDDNNNVGEWSPFVPINMKF 2568
            MRGIFSIYCLNLVFSQIYCQTQEVFLDSERNIQNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNK SAKFSSYKIPTFQILLRRGRQIVLVLDRSGSMNEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFN KSNSTLRKLAKGSNGSYQRLSGNVSLDNIFTKLLLKTKTKTLDKKIELFLKDKSYKYSYNATYQANVTTVNVNIEKNLRKYMVKMSNKSGLEILPKSTNLNPRDTQLVFEIKGQLKPGKYYLTFLKSEKKSKHHNNPKNAEKILKNIKFSIYAENKKSNQRRINPVGFISKTFFEEVDSKTFLTVTVDLSGCDITNEERANVILEINLPSDKKVFKILKDDGIGDDSISNDKIYTVNIYPKDLLEKGFYNFIAQVEIINMKTTKEKIKRTVIFESLQVKDVKDSAWTDAISPAQMIQLKIKIIDRNRIQLKTFATGDDSMEGQINRYQIIVRSKEDKTFDVLKSAKPYEEIFFDLDLWDLDNMSSMEVAVRGIDDNNNVGEWSPFVPINMKF
Sbjct:    1 MRGIFSIYCLNLVFSQIYCQTQEVFLDSERNIQNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKNSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSMNEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNKKSNSTLRKLAKGSNGSYQRLSGNVSLDNIFTKLLLKTKTKTLDKKIELFLKDKSYKYSYNATYQANVTTVNVNIEKNLRKYMVKMSNKSGLEILPKSTNLNPRDTQLVFEIKGQLKPGKYYLTFLKSEKKSKHHNNPKNAEKILKNIKFSIYAENKKSNQRRINPVGFISKTFFEEVDSKTFLTVTVDLSGCDITNEERANVILEINLPSDKKVFKILKDDGIGDDSISNDKIYTVNIYPKDLLEKGFYNFIAQVEIINMKTTKEKIKRTVIFESLQVKDVKDSAWTDAISPAQMIQLKIKIIDRNRIQLKTFATGDDSMEGQINRYQIIVRSKEDKTFDVLKSAKPYEEIFFDLDLWDLDNMSSMEVAVRGIDDNNNVGEWSPFVPINMKF 835
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Planmine SMEST
Match: SMESG000080916.1 (SMESG000080916.1)

HSP 1 Score: 390.578 bits (1002), Expect = 4.470e-121
Identity = 268/838 (31.98%), Postives = 452/838 (53.94%), Query Frame = 1 
Query:   91 LNLVFSQIYCQTQEVFLDSERNIQNFVIQISEKISKYDRKLIENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFS-SYKIPTFQILLRRGRQIVLVLDRSGSMNEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTRNDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSYQRLSGNVSLDNIFXXXXXXXXXXXXXXXIELFLKDKSYKYSYNATYQANVTTVNVNIEKNLRKYMVKMSNKSGLE---ILPKSTNLNP-------RDTQLVFEIKGQLKPGKYYLTFLKSEKKSKHHNNPKNAEKILKNIKFSIYAENKKSNQRRINPVGFISKTFFEEVDSKTFLTVTVDLSGCDITNEERANVILEINLPSDKKVFKILXXXXXXXXXXXXXXIYTVNIYPKDLLEKGFYNFIAQVEIINMKTTKEKIKRTVIFESLQVKDVKDSAWTDAISPAQMIQLKIKIIDRNRI-QLKTFATGDDSMEGQINRYQIIVRSKEDKTFDVLKSAKPYEEIFFDLDLWDLDNMSSMEVAVRGIDDNNNVGEWSPFVPINMKF 2568
            L + F  +     E +LDS    Q+ ++ I++ + + + +L+  I   +  ASKSL+KATS+++ +  G++FG + I VP+ W   +        + A F  V   N   ++KP TKQ  KCG PG ++RF   FF    LN  D+ K+GK  M+EFVKLRYGV+SE P +N L   +  + I+ +C  +I+W V     +C + N+ CKY I  NQ+HN+SIMFD+++ TS+YFC+D+ R HN  AYNLHN  C  +SV++VI+ H+DF  KS K S  Y+   F I+  +  +IVLVLD SGSM    + +K     F+ E    SA + IV ++    I+S L  +     R  L  +++ +   G + I  G+  G+ +L    T   N + ++IL+TD + + +  Y Y  +I  L + ++ ++ +++   ++ +L  +  G+NG Y+  + N    ++  K   ++   ++D  I+   +  +    Y   +  N+T ++  I  NL+  M   ++KS  E   I PK+  + P         T   FEI G   PG Y +  LKS    +   N          +  ++ A+  K+ +R I+P G IS +  +E+   T +TV VDL+ C I  +E   VIL+I  P+       + D+G+GDD++ +DK++T  +Y +DL + GFY+F A + I N+    + I+RT+   SL++   +   + D I PA++  + ++  ++ ++ ++   ATG+D M G I+ Y+I ++S E         A P E+I F+++L  ++  +  E++VRG+D++ N GEWS  VP N K+
Sbjct:    4 LYICFGLLSFVYAEYYLDSNNKFQDILVFINDNVEEENGQLLNRIMDHVSNASKSLWKATSHMESNIAGVQFGTVHIRVPSTWSNHLNPITWHQCNNALF-FVAVDNIDKNEKPITKQLGKCGDPGNFTRFPESFFKATKLN--DTFKRGKEFMREFVKLRYGVYSEEPLRNRLLAFDGKNHIQAVCGNDIKWNVVKDRHQCMESNTECKYEIIKNQHHNHSIMFDTETFTSEYFCDDRHRLHNKYAYNLHNKKCNKRSVTNVILNHKDF--KSGKTSIIYENVKFNIVKGQTEKIVLVLDTSGSMVNIIENMKLATIAFL-ESVGNSAYVGIVRFDSSATILSYLMHI--GTHRATLIREIQNLYANGGTNIPDGLVKGVQVLGGEITNDNNVIGSIILLTDGENNNNIPYSYDYVINKLIKKKLTVNAIAYGKLADMSLNMITTGTNGKYKFANPNTQYTDLAGKFFSQSCDISVDHLIKAIEETITINL-YEKVHTQNLTYIDRYIGVNLKITMTIPADKSNYEVTLITPKNKRIVPSKKITQNSGTTFSFEIIGTPDPGMYVVE-LKSPTNKRFKRNTD-----FFTLAITVSAKPSKNKERDISPSGGISTSEIKELGDTTSVTVDVDLTNCGILKDENVTVILKIESPNKPLKHLQMTDNGLGDDAMEDDKVFTRVLYARDLEDVGFYSFRADITINNI-VNGDIIRRTLDLGSLRINQKQTKKFEDKILPAKIDDILVRGDEKKKVLKIDLIATGNDGMIGNISDYEIKIQSNETIVIRKTAFANPAEKIMFEVELLKMNVTNPFEISVRGVDNSFNFGEWSNSVPYNWKY 825
[Close]
BLAST of Calcium-activated chloride channel regulator 1 vs. Planmine SMEST
Match: SMESG000080918.1 (SMESG000080918.1)

HSP 1 Score: 361.688 bits (927), Expect = 2.649e-111
Identity = 255/774 (32.95%), Postives = 420/774 (54.26%), Query Frame = 1 
Query:  295 GIKFGKIFISVPNQWQTEIQVSPKKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSLNEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNIQWKVNNSPEK---CSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDRPHNHLAYNLHNIFCKGKSVSSVIMKHQDF-NKKSAKFSSYKIPTFQILLRRGRQIVLVLDRSGSMNEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNIVSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNIL---LENNTKTRNDLQTMILITD-EQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLRKLAKGSNGSYQRLSGNVSLDNIFXXXXXXXXXXXXXXXIELFLKDK---------SYKYSYNATYQANVTTVNVNIEK-NLRKYMVKMSNKSGLEILPKSTNLNPRDTQLV--FEIKGQLKPGKYYLTFLKSEKKSKHHNNPKNAEKILKNIKFSIYAENKKSNQRRINPVGFISKTFFEEVDSKTFLTVTVDLSGCDITNEERANVILEINLPSDKKVFKILXXXXXXXXXXXXXXIYTVNIYPKDLLEKGFYNFIAQVEIINMKTTKEKIKRTVIFESLQVKDVKDSAWTDAISPAQMIQLKIKIIDRNRIQLKTFATGDDSMEGQINRYQIIVRSKEDKTFDVLKSAKPYEEIFFDLDLWDLDNMSSMEVAVRGIDDNNNVGEWSPFVPI 2556
            G+KFGK+ I +P+ W+ +   +       A   I+P+  K   + P+TKQ  KCG  G+Y    ++              +G++IM+E+VKLRYGV+ E    N   V     L+  +CN NI+ +      K   C+D N +C + I  NQNHNYS+MFD+++ +S YFC+DK+RPHN  A N  N  C  KS++SVI+ H DF N  S     Y+ PTF I+  + R+IVL+LD SGSM ++   +K+ + +F+    E++AEI +VT++   + +S +  ++    +K +N+ +  I   G + IG G++ G+ +L   + NN        T++L++D E +  ++   Y+DI+  + R  I  +V+S+N +S+  L KL + + G++  +  N S  +I  +     ++     K    LK+K            + +      +   ++++I      KY +K++ K+ +EI  K T   P + ++   F I   +K G  Y+ F++  K SK        +  + ++  +I+ ++    +RR +P   +S +F EEV+  T +T TV L+    +N     V LEI LP+   V K + DDG+ DDSI  D ++T  I PKD+ +KG YNF   +EI   + + + +++ VIF SL VK+V  SA+ D I PAQM +  IKI+    I+LKT ATG+D MEG+I++Y+I++RS  D   +    A+PYE I   LD+ ++      E+++RG+D N N G WS  VP+
Sbjct:    7 GVKFGKVSIIIPSHWKLKGDSNSGLHCGDAQINILPKTPK---NIPFTKQLRKCGISGEYISIPTDILKLTG--------RGRQIMREYVKLRYGVYDEEVINNQAKVLTKDGLVNSVCNSNIELEFERPHTKMIKCTDSNDLCHFKIKKNQNHNYSVMFDTETPSSKYFCDDKNRPHNKYAKNYQNKLCNQKSITSVILNHTDFKNVFSFPKIYYEPPTFNIIQTKHRKIVLILDISGSMADYIATMKNAIKEFVNNLIEDTAEIGLVTFSDSASKLSDMIPMNKMENKKIINNLLDNIYVHGGTNIGHGLQIGVEVLGGTIFNNATLDG---TLLLLSDGENHEENEDMPYNDIVDVIVRKSIQTNVVSYN-QSDVLLTKLTRNTGGNFVHVKINSSSLDIMNRFARALESCDGKLKENTVLKEKIVVSQKSGKRIPFIFVDKLMGDDRKISISISSLTASKYDLKLTTKNNMEI--KLTAKIPDNDKVAYCFSIPNSIKSGNLYVEFIR--KGSKRVKRSLKEKPFIYSLDNTIFTDD----ERRFHPEAQLSHSFVEEVNGNTIITATVFLTNFYSSNLYLVRVSLEIELPNSIIVKKKMMDDGLEDDSIKGDLVFTKLILPKDISKKGVYNFKGIIEIYK-EHSLQILRKDVIFNSLLVKNVSPSAFIDKIPPAQMEEPVIKILKNKLIKLKTIATGNDGMEGKISKYEILIRSSSDYIIEKSVYAEPYERIEIILDISNIMLQKVGEISIRGVDYNGNFGMWSFGVPL 756
The following BLAST results are available for this feature:
BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
CLCA46.521e-2725.06chloride channel accessory 4 [Source:HGNC Symbol;A... [more]
CLCA17.658e-2624.21chloride channel accessory 1 [Source:HGNC Symbol;A... [more]
CLCA17.658e-2624.21chloride channel accessory 1 [Source:HGNC Symbol;A... [more]
CLCA21.185e-2024.32chloride channel accessory 2 [Source:HGNC Symbol;A... [more]
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BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
clca13.479e-3326.52chloride channel accessory 1 [Source:ZFIN;Acc:ZDB-... [more]
clca12.766e-3126.46chloride channel accessory 1 [Source:ZFIN;Acc:ZDB-... [more]
clca18.646e-1825.09chloride channel accessory 1 [Source:ZFIN;Acc:ZDB-... [more]
clca15.010e-1727.04chloride channel accessory 1 [Source:ZFIN;Acc:ZDB-... [more]
clca5.12.970e-826.43chloride channel accessory 5, tandem duplicate 1 [... [more]
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BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000038434.16.940e-3126.16chloride channel accessory 1 gene 2 [Source:NCBI g... [more]
ENSXETT00000026373.17.873e-3126.16chloride channel accessory 1 gene 2 [Source:NCBI g... [more]
ENSXETT00000038492.15.117e-2826.37chloride channel accessory 4 gene 1 [Source:NCBI g... [more]
gnl37.074e-2725.45guanine nucleotide binding protein-like 3 (nucleol... [more]
csnk2a21.342e-2526.11casein kinase 2 alpha 2 [Source:Xenbase;Acc:XB-GEN... [more]
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BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Clca3a12.212e-2725.00chloride channel accessory 3A1 [Source:MGI Symbol;... [more]
Clca3a12.376e-2725.00chloride channel accessory 3A1 [Source:MGI Symbol;... [more]
Clca3a29.087e-2724.55chloride channel accessory 3A2 [Source:MGI Symbol;... [more]
Clca11.383e-2624.61chloride channel accessory 1 [Source:MGI Symbol;Ac... [more]
Clca3b5.317e-2625.72chloride channel accessory 3B [Source:MGI Symbol;A... [more]
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BLAST of Calcium-activated chloride channel regulator 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P54281|CLCA1_BOVIN2.546e-3125.95Calcium-activated chloride channel regulator 1 OS=... [more]
sp|Q2TU62|CLCA1_HORSE8.430e-3126.29Calcium-activated chloride channel regulator 1 OS=... [more]
sp|Q9TUB5|CLCA1_PIG1.502e-2625.56Calcium-activated chloride channel regulator 1 OS=... [more]
sp|Q9QX15|CA3A1_MOUSE1.547e-2625.00Calcium-activated chloride channel regulator 3A-1 ... [more]
sp|Q14CN2|CLCA4_HUMAN3.132e-2625.06Calcium-activated chloride channel regulator 4 OS=... [more]
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BLAST of Calcium-activated chloride channel regulator 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3N0YDY52.494e-3328.25Calcium-activated chloride channel regulator 3A-1 ... [more]
A0A267GPW82.951e-3325.27VWFA domain-containing protein OS=Macrostomum lign... [more]
T1II735.550e-3328.96VWFA domain-containing protein OS=Strigamia mariti... [more]
A0A267GGI11.424e-3225.49VWFA domain-containing protein OS=Macrostomum lign... [more]
A0A369S8L64.164e-3226.91Epithelial chloride channel protein OS=Trichoplax ... [more]
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BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000007776.22.403e-3126.19calcium-activated chloride channel regulator 1 [So... [more]
ENSAMXT00000037970.11.077e-2926.25calcium-activated chloride channel regulator 1 [So... [more]
ENSAMXT00000007818.25.007e-2726.82pep primary_assembly:Astyanax_mexicanus-2.0:1:5630... [more]
ENSAMXT00000054901.14.604e-1626.87pep primary_assembly:Astyanax_mexicanus-2.0:1:5707... [more]
ENSAMXT00000007808.29.882e-1526.11pep primary_assembly:Astyanax_mexicanus-2.0:1:5707... [more]
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BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CLCA11.174e-3125.94chloride channel accessory 1 [Source:HGNC Symbol;A... [more]
CLCA11.296e-3026.23chloride channel accessory 1 [Source:HGNC Symbol;A... [more]
CLCA15.295e-2623.98chloride channel accessory 1 [Source:HGNC Symbol;A... [more]
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BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Calcium-activated chloride channel regulator 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Calcium-activated chloride channel regulator 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000080919.10.000e+099.76SMESG000080919.1[more]
SMESG000080916.14.470e-12131.98SMESG000080916.1[more]
SMESG000080918.12.649e-11132.95SMESG000080918.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023396 ID=SMED30023396|Name=Calcium-activated chloride channel regulator 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2935bp
TAAGTACAAAGTGGTCATCATCGTCAGATTTAATAACCGACCTTCAAAAA
AAAATAAAATTGAATGAGAGGAATCTTTTCAATATATTGTTTGAATTTAG
TATTCTCACAAATTTACTGTCAAACTCAAGAGGTTTTTTTAGACTCAGAA
AGAAATATTCAAAATTTTGTCATTCAAATTAGCGAAAAGATTTCAAAATA
TGATAGAAAGCTGATTGAAAATATAAAAATTTCAATGGAACAGGCATCTA
AATCCCTGTATAAGGCTACTAGTAATCTGGACAAATCTCAACCAGGAATT
AAGTTTGGGAAGATTTTCATCAGTGTTCCGAATCAATGGCAAACTGAAAT
TCAAGTTTCGCCAAAAAAATTTACCGATAAAGCGCATTTCAAAATTGTTC
CGAGAAAAAATAAAAAGAATTCCGACAAACCTTGGACAAAACAATATCCG
AAATGCGGAAAGCCTGGAAAATACTCCAGATTTTCATCAGAATTTTTTAA
TGAAAAGTCATTGAATGAGAAGGATTCATTGAAAAAAGGGAAAAGAATAA
TGAAAGAATTTGTGAAACTGAGATATGGAGTATTCAGTGAACGTCCATAC
AAAAATGTTTTGTTTGTTCACAATAACTTCAGTTTGATCAAAGGAATATG
TAATCAAAATATTCAGTGGAAAGTGAATAACTCTCCTGAAAAATGCAGTG
ATGAAAATTCTGTTTGTAAATACACAATAGATGGAAACCAAAATCATAAC
TACTCAATAATGTTTGATAGTGACAGCCACACAAGTGACTATTTCTGTAA
TGACAAGGATAGACCTCACAATCATCTTGCCTATAATTTACATAATATAT
TTTGCAAGGGAAAAAGTGTTTCGTCAGTAATTATGAAGCATCAAGATTTT
AATAAAAAATCTGCTAAATTTAGTTCTTATAAAATTCCAACGTTTCAAAT
ATTACTGCGAAGAGGTAGACAAATTGTTTTGGTATTGGATCGCTCAGGCA
GCATGAATGAATTTGCAGACAAAGTAAAAGACGTAGTTTGTAAATTCATC
AAGGAATATGCTGAGGAGTCTGCTGAAATCTCCATTGTCACATATAATAA
AGAAGTAAATATAGTTTCACCGCTAACCAGGGTTGACAATGCCAATACAA
GAAAACATTTGAATGATCAAGTTAAAATGATAAAATTTTTTGGGCTGTCT
AAAATTGGTAAAGGAATAAAAACAGGAATGAATATTTTGCTTGAAAATAA
TACGAAAACTCGAAATGATTTACAAACAATGATTTTAATAACGGATGAAC
AATATTCGAGAGACAAAAAATATAAATATTCTGATATAATTAAAGCATTA
AAAAGATCGGAAATTATCCTTCATGTCCTTTCTTTCAATAACAAATCGAA
TTCGACTCTAAGGAAATTGGCTAAAGGTTCAAACGGAAGTTATCAAAGAT
TATCGGGAAACGTTTCGCTTGATAATATATTTACGAAATTATTACTGAAA
ACTAAAACAAAAACGTTGGATAAAAAAATTGAGTTATTCCTAAAGGATAA
ATCCTATAAATACTCTTACAATGCGACTTACCAAGCTAATGTTACAACTG
TCAATGTAAATATAGAAAAGAACCTAAGAAAATACATGGTAAAAATGTCA
AATAAATCAGGTTTAGAAATTCTACCAAAATCAACAAACTTAAACCCAAG
AGATACGCAGTTAGTATTTGAAATAAAAGGCCAGTTGAAACCTGGAAAAT
ATTATCTGACCTTTTTAAAGTCAGAAAAAAAATCAAAACATCATAACAAC
CCAAAAAACGCGGAAAAAATATTGAAAAATATCAAATTTTCAATTTATGC
AGAAAATAAAAAATCAAATCAAAGAAGAATTAATCCAGTTGGTTTTATTT
CAAAGACATTTTTTGAAGAGGTCGACAGCAAAACTTTTCTGACAGTTACG
GTTGACCTTTCTGGATGCGATATAACGAATGAGGAACGAGCGAATGTGAT
TTTAGAAATAAATTTACCAAGTGATAAAAAAGTTTTCAAAATATTAAAGG
ATGATGGAATTGGAGATGATTCAATTTCTAATGACAAAATCTATACCGTA
AACATCTATCCGAAAGACCTTCTAGAAAAAGGATTTTACAATTTTATTGC
ACAAGTAGAAATAATAAATATGAAAACCACTAAAGAAAAAATTAAACGAA
CAGTGATCTTTGAAAGTTTACAAGTAAAAGATGTTAAGGATTCTGCATGG
ACAGACGCAATATCTCCAGCTCAAATGATACAACTAAAAATAAAAATAAT
TGATAGAAATAGAATTCAATTAAAGACTTTTGCCACAGGAGATGACAGCA
TGGAGGGTCAAATCAATCGCTATCAAATTATCGTGAGATCAAAGGAAGAC
AAAACTTTCGACGTACTAAAATCAGCAAAGCCATACGAAGAAATATTTTT
TGATCTTGATTTGTGGGACTTAGATAATATGTCTTCAATGGAAGTAGCAG
TTAGAGGAATCGACGACAACAACAATGTTGGAGAATGGTCTCCGTTTGTT
CCAATTAATATGAAATTTTAAATAGTCAGAAAATATAATTTTTACATTGA
TTTTGTGAATTCAAAGAAAAAAATATTCTTATAATTTATTTAACATTTAT
AGTTTATACTTAATAATTGAATGAAGTCTTTTAATATAATTATAATGAAG
TGACATAATTTATAATAACAATTTTCGTGAGAATGTTGTTTTCCAACTTA
GCAATTATGGTGTATATCTGTGGTAATATCTATATACATGACTATGCCAA
CTTCAACAAAAGTTGCGGACATACAAACGTACAACGATAATAATTATGCA
TATTGATGATAATGATTATCAAATAAACATTGTAAACTTTTCAAATTGCA
TGTAGATTTTTGATATATTCTATAGATTTAAAAAA
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protein sequence of SMED30023396-orf-1

>SMED30023396-orf-1 ID=SMED30023396-orf-1|Name=SMED30023396-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=836bp
MRGIFSIYCLNLVFSQIYCQTQEVFLDSERNIQNFVIQISEKISKYDRKL
IENIKISMEQASKSLYKATSNLDKSQPGIKFGKIFISVPNQWQTEIQVSP
KKFTDKAHFKIVPRKNKKNSDKPWTKQYPKCGKPGKYSRFSSEFFNEKSL
NEKDSLKKGKRIMKEFVKLRYGVFSERPYKNVLFVHNNFSLIKGICNQNI
QWKVNNSPEKCSDENSVCKYTIDGNQNHNYSIMFDSDSHTSDYFCNDKDR
PHNHLAYNLHNIFCKGKSVSSVIMKHQDFNKKSAKFSSYKIPTFQILLRR
GRQIVLVLDRSGSMNEFADKVKDVVCKFIKEYAEESAEISIVTYNKEVNI
VSPLTRVDNANTRKHLNDQVKMIKFFGLSKIGKGIKTGMNILLENNTKTR
NDLQTMILITDEQYSRDKKYKYSDIIKALKRSEIILHVLSFNNKSNSTLR
KLAKGSNGSYQRLSGNVSLDNIFTKLLLKTKTKTLDKKIELFLKDKSYKY
SYNATYQANVTTVNVNIEKNLRKYMVKMSNKSGLEILPKSTNLNPRDTQL
VFEIKGQLKPGKYYLTFLKSEKKSKHHNNPKNAEKILKNIKFSIYAENKK
SNQRRINPVGFISKTFFEEVDSKTFLTVTVDLSGCDITNEERANVILEIN
LPSDKKVFKILKDDGIGDDSISNDKIYTVNIYPKDLLEKGFYNFIAQVEI
INMKTTKEKIKRTVIFESLQVKDVKDSAWTDAISPAQMIQLKIKIIDRNR
IQLKTFATGDDSMEGQINRYQIIVRSKEDKTFDVLKSAKPYEEIFFDLDL
WDLDNMSSMEVAVRGIDDNNNVGEWSPFVPINMKF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0005576extracellular region
GO:0005615extracellular space
GO:0005887integral component of plasma membrane
GO:0005902microvillus
GO:0016021integral component of membrane
GO:0030141secretory granule
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002075pigment cell
PLANA:0003116parenchymal cell
PLANA:0007528glial cell
Vocabulary: INTERPRO
TermDefinition
IPR036465vWFA_dom_sf
IPR002035VWF_A
IPR013642CLCA_N
Vocabulary: molecular function
TermDefinition
GO:0005229intracellular calcium activated chloride channel activity
GO:0008233peptidase activity
GO:0008237metallopeptidase activity
GO:0016787hydrolase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
GO:0006810transport
GO:0006811ion transport
GO:0006816calcium ion transport
GO:0006821chloride transport
GO:1902476chloride transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002035von Willebrand factor, type ASMARTSM00327VWA_4coord: 301..481
e-value: 2.2E-20
score: 83.7
IPR002035von Willebrand factor, type APFAMPF00092VWAcoord: 304..471
e-value: 7.7E-18
score: 65.3
IPR002035von Willebrand factor, type APROSITEPS50234VWFAcoord: 303..476
score: 15.712
IPR036465von Willebrand factor A-like domain superfamilyGENE3DG3DSA:3.40.50.410coord: 298..480
e-value: 4.3E-23
score: 84.3
IPR036465von Willebrand factor A-like domain superfamilySUPERFAMILYSSF53300vWA-likecoord: 300..476
IPR013642Calcium-activated chloride channel, N-terminalPFAMPF08434CLCAcoord: 33..283
e-value: 2.9E-26
score: 92.4
NoneNo IPR availablePANTHERPTHR10579CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATORcoord: 33..456
NoneNo IPR availablePANTHERPTHR10579:SF66CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 2coord: 33..456
NoneNo IPR availableCDDcd00198vWFAcoord: 302..460
e-value: 8.31045E-15
score: 70.6726
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..19
score: 0.458