Potassium channel subfamily K member 18

Overview


Name	Potassium channel subfamily K member 18
Smed ID	SMED30023385
Length (bp)	2200

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Potassium channel subfamily K member 18 (SMED30023385) t-SNE clustered cells

Violin plots show distribution of expression levels for Potassium channel subfamily K member 18 (SMED30023385) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Potassium channel subfamily K member 18 (SMED30023385) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Potassium channel subfamily K member 18 (SMED30023385) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30023385

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
muscle cell	SMED30023385	SMESG000031911.1	dd_Smed_v4_15695_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30023385	SMESG000031911.1	dd_Smed_v4_15695_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Match: KCNK18 (potassium two pore domain channel subfamily K member 18 [Source:HGNC Symbol;Acc:HGNC:19439])

HSP 1 Score: 106.301 bits (264), Expect = 6.293e-24
Identity = 81/282 (28.72%), Postives = 134/282 (47.52%), Query Frame = 2

Query: 1217 FNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENP--------------------SSILKKENTTKPTMHSFRMS-----LPLGNANF-----MDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESC-YFVFITLTTIGFGDLV---PGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKV 1957
            FN    W+F  +L +  T+ +T+GYG+I P T  G++L ++YA+ GIPLM L LT+ G ++A +    Y RF  F  + +    K C + L   + +   +  ++  P+ I    E P                    S  L+K+NT +    +   S     L LG  ++     +D V +  E +D+P+ +   I+  YI   AA+  +W+    FE+  YF F+TLTTIGFGD V   P  F            +F + Y++ G+ +  + F L+Q ++
Sbjct:   95 FNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNRFRKFPFFTRPLLSKWCPKSLFKKKPD--PKPADEAVPQIIISAEELPGPKLGTCPSRPSCSMELFERSHALEKQNTLQLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHPNFF------------LFFSIYIIVGMEIVFIAFKLVQNRL 362

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Match: KCNK9 (potassium two pore domain channel subfamily K member 9 [Source:HGNC Symbol;Acc:HGNC:6283])

HSP 1 Score: 72.4034 bits (176), Expect = 6.653e-13
Identity = 67/245 (27.35%), Postives = 96/245 (39.18%), Query Frame = 2

Query: 1220 NGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
               + W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+          R   F  Y+  R +K C  +  D                            +  EN       S   +L +G A F                                 S  + W+FF + Y+ FITLTTIGFGD V     L  K   Q K ++ AF   Y++ GL V      L+
Sbjct:   61 RAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE----------RMNTFVRYLLKRIKKCCGMRNTD----------------------------VSMENMVTVGFFSCMGTLCIGAAAF---------------------------------SQCEEWSFFHAYYYCFITLTTIGFGDYV----ALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLV 230

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Match: KCNK9 (potassium two pore domain channel subfamily K member 9 [Source:HGNC Symbol;Acc:HGNC:6283])

HSP 1 Score: 72.4034 bits (176), Expect = 6.878e-13
Identity = 67/245 (27.35%), Postives = 96/245 (39.18%), Query Frame = 2

Query: 1220 NGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
               + W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+          R   F  Y+  R +K C  +  D                            +  EN       S   +L +G A F                                 S  + W+FF + Y+ FITLTTIGFGD V     L  K   Q K ++ AF   Y++ GL V      L+
Sbjct:   73 RAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE----------RMNTFVRYLLKRIKKCCGMRNTD----------------------------VSMENMVTVGFFSCMGTLCIGAAAF---------------------------------SQCEEWSFFHAYYYCFITLTTIGFGDYV----ALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLV 242

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Match: KCNK9 (potassium two pore domain channel subfamily K member 9 [Source:HGNC Symbol;Acc:HGNC:6283])

HSP 1 Score: 72.4034 bits (176), Expect = 6.878e-13
Identity = 67/245 (27.35%), Postives = 96/245 (39.18%), Query Frame = 2

Query: 1220 NGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
               + W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+          R   F  Y+  R +K C  +  D                            +  EN       S   +L +G A F                                 S  + W+FF + Y+ FITLTTIGFGD V     L  K   Q K ++ AF   Y++ GL V      L+
Sbjct:   73 RAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE----------RMNTFVRYLLKRIKKCCGMRNTD----------------------------VSMENMVTVGFFSCMGTLCIGAAAF---------------------------------SQCEEWSFFHAYYYCFITLTTIGFGDYV----ALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLV 242

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Match: KCNK9 (potassium two pore domain channel subfamily K member 9 [Source:HGNC Symbol;Acc:HGNC:6283])

HSP 1 Score: 72.4034 bits (176), Expect = 6.878e-13
Identity = 67/245 (27.35%), Postives = 96/245 (39.18%), Query Frame = 2

Query: 1220 NGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
               + W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+          R   F  Y+  R +K C  +  D                            +  EN       S   +L +G A F                                 S  + W+FF + Y+ FITLTTIGFGD V     L  K   Q K ++ AF   Y++ GL V      L+
Sbjct:   73 RAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE----------RMNTFVRYLLKRIKKCCGMRNTD----------------------------VSMENMVTVGFFSCMGTLCIGAAAF---------------------------------SQCEEWSFFHAYYYCFITLTTIGFGDYV----ALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLV 242

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Match: twk-48 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q7YWY7])

HSP 1 Score: 159.844 bits (403), Expect = 6.622e-43
Identity = 98/256 (38.28%), Postives = 146/256 (57.03%), Query Frame = 2

Query: 1205 NGYVFNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTC---FKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPL-TILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVK 1960
            +G  +     WTF+GA LYS+T+ITTIGYG+   KT+ G+ LT++YAIIGIPLMLL LTN+G VMA +F+F+Y  +    F++ +  +KRK  K +  +S  ++  R         ++       + ++   T +  M    +          ++     E + VPI L + T+LG Y+ VG  +F  W+GWTF ES YF FI+LTTIGFGD  P    +    + Q K +  + YL+ G+A+ AMCF L QE+V+
Sbjct:  110 DGKEYGKQAQWTFTGAFLYSLTVITTIGYGNTAAKTYIGKTLTMLYAIIGIPLMLLFLTNIGDVMAKIFRFLYAQSIRLKFRLILWHKKRKAAKIRRANSLVSRLTRGHRVKADSSVDSFGLGAGADVEDLLTARVEMEQLEVR---------ETAAAQLESMTVPISLVVFTMLG-YLGVGTTIFKVWEGWTFLESFYFCFISLTTIGFGDKFPST-SVSNTDEAQEKLVITSIYLLFGMALLAMCFNLAQEEVQ 354

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Match: twk-28 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q22940])

HSP 1 Score: 109.383 bits (272), Expect = 9.300e-25
Identity = 73/282 (25.89%), Postives = 136/282 (48.23%), Query Frame = 2

Query: 1175 LILSVFNATRNGYVF---------NGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYR-FTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRI 1990
            L+ ++F A RN ++             +LWTF  ++ ++ T+ITTIGYG++VP T +GR   I++A++GIPL+L+ + ++GK +++   ++YR +  FK  ++ R+ K+   +      ++       +K   +N+   +                              DS     +E+ +P+++ L +L  Y  +G  +F  W+   +FE+ YF FIT+ T+GFGD+VP          +Q    F   Y++ GL++  MC  L   +       LG ++
Sbjct:  137 LVKNMFQAYRNQFITAKHLLNKTREDEVLWTFPNSMFFAATVITTIGYGNLVPITVTGRVACIIFALLGIPLLLVTIADIGKFLSEFLSYLYRSYRGFKRKLR-RQSKKITSQYRSQSQSRSSSVMGSSKAGSMNLHDIDS-----------------------------DSEDSAGDELRIPVFMVLLVLLAYTAIGGFLFQSWEHLEYFEAFYFCFITMATVGFGDIVP---------NEQVYVFFTMAYIIFGLSLATMCIDLAGTEYIRKIHYLGTKM 379

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Match: twk-31 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q6EUT8])

HSP 1 Score: 107.071 bits (266), Expect = 1.634e-23
Identity = 84/270 (31.11%), Postives = 125/270 (46.30%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSR--KRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDG-WTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLV-TGLAVFAMCFTLIQEKVKEWF--------EELGKRIGLI*SE 2008
            W + GAL Y  T+ TTIGYG+I P+T  GR  ++VYAI+GIPL+L  L+  GK M D     ++    ++  K++  K +   +K+L S       +G +  PE                   KP +                      E   +PIWL L I  +Y+   +++F  W+  WTFF S YF  I+L TIG GD+VP          D+       F LV  GL++ +M  +++Q K++EW         EE  K+ GL+  E
Sbjct:  227 WDYWGALFYVGTLFTTIGYGNIYPRTALGRAASVVYAIVGIPLVLAILSKCGKWMTDSLSEKWQQHRIQITEKAKMTKNRLRGKKILKSGEIVEANTGAEADPE------------------KKPEV----------------------ESRTIPIWLALLICVVYVAGCSSLFLLWETRWTFFTSLYFFCISLLTIGLGDIVP----------DKPHMFIVMFVLVIVGLSIVSMFISVVQIKIEEWLCRMIEQIKEEYMKKDGLVDPE 446

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Match: twk-31 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q6EUT8])

HSP 1 Score: 106.686 bits (265), Expect = 1.946e-23
Identity = 84/270 (31.11%), Postives = 125/270 (46.30%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSR--KRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDG-WTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLV-TGLAVFAMCFTLIQEKVKEWF--------EELGKRIGLI*SE 2008
            W + GAL Y  T+ TTIGYG+I P+T  GR  ++VYAI+GIPL+L  L+  GK M D     ++    ++  K++  K +   +K+L S       +G +  PE                   KP +                      E   +PIWL L I  +Y+   +++F  W+  WTFF S YF  I+L TIG GD+VP          D+       F LV  GL++ +M  +++Q K++EW         EE  K+ GL+  E
Sbjct:  227 WDYWGALFYVGTLFTTIGYGNIYPRTALGRAASVVYAIVGIPLVLAILSKCGKWMTDSLSEKWQQHRIQITEKAKMTKNRLRGKKILKSGEIVEANTGAEADPE------------------KKPEV----------------------ESRTIPIWLALLICVVYVAGCSSLFLLWETRWTFFTSLYFFCISLLTIGLGDIVP----------DKPHMFIVMFVLVIVGLSIVSMFISVVQIKIEEWLCRMIEQIKEEYMKKDGLVDPE 446

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Match: twk-13 (TWiK family of potassium channels [Source:UniProtKB/TrEMBL;Acc:Q21729])

HSP 1 Score: 104.76 bits (260), Expect = 4.787e-23
Identity = 77/297 (25.93%), Postives = 130/297 (43.77%), Query Frame = 2

Query: 1220 NGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMAD-LFKFMYRFTCFKVYIKSR--------------KRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISE------------------------EVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIG 1993
            +G I W+F  ++ +S T ITTIGYGHIVP+T  GR   I YA++GIPL+L+ + ++G+ +A  + K  + +     ++ +                R+      L+     +K   N N P      +       +++   +           + +A   D++ EI++                        E  V +   L I+  Y+  GA +  +W+ WTFFE+ YF F+T+TTIGFGD+VP N +    +           Y+V GL +  MC  L+  +        G+ +G
Sbjct:  210 DGPIKWSFMSSIFFSWTAITTIGYGHIVPRTDEGRVAIIFYALLGIPLILVTIADIGRFLATYIIKLHHGYMAVMSFVTNSCLKCIKWACCWIRLPRRHIPMPTLELLQRTQKLYPNNNNPTVAATAASAGGGTGRRKKQQRDN---------VSDAGTFDNISEINDGSEGGENENEGEEEEQIQFDPSNHEKRVSVLFILLIMLGYVAGGAYIVRWWEEWTFFEAFYFCFVTVTTIGFGDIVPANVDWLPAT---------LAYIVFGLIITTMCIDLVGSEYIRDIHFYGRSLG 488

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Match: sand (gene:FBgn0033257 transcript:FBtr0088780)

HSP 1 Score: 138.658 bits (348), Expect = 3.550e-35
Identity = 88/249 (35.34%), Postives = 143/249 (57.43%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEI-------SEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFEL-GEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKV 1957
            W+FSGA LYS+T+ITTIGYG+I P +  G+ +TI+YAIIG+PL LL L+N+G V+A  FK++Y   C         ++   ++    +   R    +  +    +    + SS     +++     S R S  L +  + +S  +I       ++E+ VP+ + + ++  YIL GA +F  W+ W + +  YF  I+L++IGFGDLVPG+  +  ++ + +   I CA YL+ G+AV AMCF L+QE+V
Sbjct:  127 WSFSGAFLYSLTVITTIGYGNITPHSECGKLVTILYAIIGMPLFLLYLSNIGDVLAKSFKWIYSKVCLCRICPGVAKRRIIRERRKMRQLARALQMHDMENARGSSSYTSTSSTTSSNSSSSEYTRSSRQSSSLVDIQYTESDSDIEREIRGSTDEITVPVTVCVFVMVGYILWGALLFGRWEDWNYLDGSYFCLISLSSIGFGDLVPGDRVITADRDKVEVSFILCAIYLLLGMAVIAMCFNLMQEQV 375

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Match: CG34396 (gene:FBgn0085425 transcript:FBtr0112644)

HSP 1 Score: 122.865 bits (307), Expect = 5.290e-29
Identity = 89/268 (33.21%), Postives = 139/268 (51.87%), Query Frame = 2

Query: 1202 RNGYVFNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQ---NNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWD-GWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIG 1993
            R+G V N +  W+F  A++YS TI TTIGYGHI PKT  GR LTIVYAIIGIP+ L+ L +LGK+     KF++ +     Y +S +R   +Q++  +    N     +  +    F N   EN     ++         S   S P    +      E+ +E ++P+ +   +L  YIL+G+  F   +  WT  ++ Y+VFI+++TIGFGDLVP N             +    YL+ GLA+ +M   ++Q K+ + F+    ++G
Sbjct:  193 RSGMVDNTDP-WSFWDAMVYSATIYTTIGYGHITPKTGMGRSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMFFSNSAPEND----EESQADAEAARSVGTSHPETPTSPYPETFEVDDEFNLPVSVASLLLITYILLGSFGFLMMEPSWTPLDAFYYVFISMSTIGFGDLVPSN---------PFYVMVSMIYLMFGLALTSMFINVVQIKLSDHFKMASAKVG 446

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Match: CG34396 (gene:FBgn0085425 transcript:FBtr0112645)

HSP 1 Score: 115.931 bits (289), Expect = 3.057e-26
Identity = 84/264 (31.82%), Postives = 134/264 (50.76%), Query Frame = 2

Query: 1217 FNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQ---NNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWD-GWTFFESCYFVFITLTTIGFGDLVPGN-FELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIG 1993
            + G   W F    ++  T+ITTIGYGHI PKT  GR LTIVYAIIGIP+ L+ L +LGK+     KF++ +     Y +S +R   +Q++  +    N     +  +    F N   EN     ++         S   S P    +      E+ +E ++P+ +   +L  YIL+G+  F   +  WT  ++ Y+VFI+++TIGFGDLVP N F +          +    YL+ GLA+ +M   ++Q K+ + F+    ++G
Sbjct:  608 YPGQKSWNFVNCFIFCWTVITTIGYGHITPKTGMGRSLTIVYAIIGIPMFLIVLADLGKLFTRCVKFLWVYVRRMYYTRSCRRIRKQQQIRSAMTGFNTMYDMAIRRPSMFFSNSAPEND----EESQADAEAARSVGTSHPETPTSPYPETFEVDDEFNLPVSVASLLLITYILLGSFGFLMMEPSWTPLDAFYYVFISMSTIGFGDLVPSNPFYV----------MVSMIYLMFGLALTSMFINVVQIKLSDHFKMASAKVG 857

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Match: CG42594 (gene:FBgn0260971 transcript:FBtr0345704)

HSP 1 Score: 110.923 bits (276), Expect = 1.184e-24
Identity = 74/262 (28.24%), Postives = 135/262 (51.53%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFK--FMYRFTC-------FKVYIKSRKRKECKQKLLDSQNNQ-RKRSGNQNKPEFI-NILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISE----------EVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKV 1957
            W F+ A LYS+T++TTIGYG++ P+T  GR +T+ YA  GIPL L+ L++ G ++A + +  F     C       +  Y + R  ++ ++     Q  + RK+     +P ++ ++    P    K      P  ++     P+G+   +  +  +S            +  PI L  +++ +YI+ GAAV    + W   +  YF F++L+TIGFGD++P     G + +    + FC+ Y+++G+ + AMCF +I E++
Sbjct:  600 WNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSSTGSILARVAREVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQQEELRKQQAVMQEPYYVRDVFHATPE---KDAGAGAPPPNA---GGPVGSVGGLGDIDSLSASESRGSMHGLSILAPILLCFSMMIIYIVFGAAVLYRLEKWPILDGIYFCFMSLSTIGFGDMLP-----GLRRESNATTWFCSVYIMSGMTLTAMCFNVIHEEI 850

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Match: CG42594 (gene:FBgn0260971 transcript:FBtr0301749)

HSP 1 Score: 110.923 bits (276), Expect = 1.184e-24
Identity = 74/262 (28.24%), Postives = 135/262 (51.53%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFK--FMYRFTC-------FKVYIKSRKRKECKQKLLDSQNNQ-RKRSGNQNKPEFI-NILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISE----------EVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKV 1957
            W F+ A LYS+T++TTIGYG++ P+T  GR +T+ YA  GIPL L+ L++ G ++A + +  F     C       +  Y + R  ++ ++     Q  + RK+     +P ++ ++    P    K      P  ++     P+G+   +  +  +S            +  PI L  +++ +YI+ GAAV    + W   +  YF F++L+TIGFGD++P     G + +    + FC+ Y+++G+ + AMCF +I E++
Sbjct:  600 WNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSSTGSILARVAREVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQQEELRKQQAVMQEPYYVRDVFHATPE---KDAGAGAPPPNA---GGPVGSVGGLGDIDSLSASESRGSMHGLSILAPILLCFSMMIIYIVFGAAVLYRLEKWPILDGIYFCFMSLSTIGFGDMLP-----GLRRESNATTWFCSVYIMSGMTLTAMCFNVIHEEI 850

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Match: kcnk18 (potassium channel, subfamily K, member 18 [Source:ZFIN;Acc:ZDB-GENE-100405-2])

HSP 1 Score: 90.1225 bits (222), Expect = 9.809e-19
Identity = 78/292 (26.71%), Postives = 137/292 (46.92%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCF-KVYIKSRK-RKECKQK----------------------LLDSQNNQR--------KRSGNQ---NKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDG-WTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF-YLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGL 1996
            WTF  +L +  T+ TT+GYG I P T  G+   ++YA++GIPLMLL ++++G ++A L    Y R   F + +I  +  R +  +K                      +L++ NNQ+        +R   Q   NK  F  I+      I  K   +K         +P       + + +  E++DVP+ + L ++  Y+++ + +   W+      ++ YF FITLTTIGFGD+VP          +  K     F +++TG+A+ +M F L Q ++  ++    K + +
Sbjct:  100 WTFFASLFFCCTVFTTVGYGRIYPLTSKGKVACVLYAMVGIPLMLLVISDVGDLLAVLLSKAYTRLNLFFRRWIGHQSWRLQSHEKTSALPQVQADTDGTYKFNQDVVVLETTNNQQVIQTRSSIRRGSFQLRNNKEIFDRIIVRESFRI--KGTLSKSCSCPELDRVPTPKDELFNDIGQEMEQLDVPLLVILLMVFAYMVICSQILKCWEKQMDHSDAFYFTFITLTTIGFGDIVP----------EHPKFFMVTFLFIITGMAIMSMAFKLGQSQIVCFYRRCIKSLSM 379

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Match: kcnk18 (potassium channel, subfamily K, member 18 [Source:ZFIN;Acc:ZDB-GENE-100405-2])

HSP 1 Score: 89.7373 bits (221), Expect = 1.278e-18
Identity = 78/292 (26.71%), Postives = 137/292 (46.92%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCF-KVYIKSRK-RKECKQK----------------------LLDSQNNQR--------KRSGNQ---NKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDG-WTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF-YLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGL 1996
            WTF  +L +  T+ TT+GYG I P T  G+   ++YA++GIPLMLL ++++G ++A L    Y R   F + +I  +  R +  +K                      +L++ NNQ+        +R   Q   NK  F  I+      I  K   +K         +P       + + +  E++DVP+ + L ++  Y+++ + +   W+      ++ YF FITLTTIGFGD+VP          +  K     F +++TG+A+ +M F L Q ++  ++    K + +
Sbjct:  100 WTFFASLFFCCTVFTTVGYGRIYPLTSKGKVACVLYAMVGIPLMLLVISDVGDLLAVLLSKAYTRLNLFFRRWIGHQSWRLQSHEKTSALPQVQADTDGTYKFNQDVVVLETTNNQQVIQTRSSIRRGSFQLRNNKEIFDRIIVRESFRI--KGTLSKSCSCPELDRVPTPKDELFNDIGQEMEQLDVPLLVILLMVFAYMVICSQILKCWEKQMDHSDAFYFTFITLTTIGFGDIVP----------EHPKFFMVTFLFIITGMAIMSMAFKLGQSQIVCFYRRCIKSLSM 379

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Match: kcnk18 (potassium channel, subfamily K, member 18 [Source:ZFIN;Acc:ZDB-GENE-100405-2])

HSP 1 Score: 89.3521 bits (220), Expect = 1.436e-18
Identity = 78/292 (26.71%), Postives = 137/292 (46.92%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCF-KVYIKSRK-RKECKQK----------------------LLDSQNNQR--------KRSGNQ---NKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDG-WTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF-YLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGL 1996
            WTF  +L +  T+ TT+GYG I P T  G+   ++YA++GIPLMLL ++++G ++A L    Y R   F + +I  +  R +  +K                      +L++ NNQ+        +R   Q   NK  F  I+      I  K   +K         +P       + + +  E++DVP+ + L ++  Y+++ + +   W+      ++ YF FITLTTIGFGD+VP          +  K     F +++TG+A+ +M F L Q ++  ++    K + +
Sbjct:  100 WTFFASLFFCCTVFTTVGYGRIYPLTSKGKVACVLYAMVGIPLMLLVISDVGDLLAVLLSKAYTRLNLFFRRWIGHQSWRLQSHEKTSALPQVQADTDGTYKFNQDVVVLETTNNQQVIQTRSSIRRGSFQLRNNKEIFDRIIVRESFRI--KGTLSKSCSCPELDRVPTPKDELFNDIGQEMEQLDVPLLVILLMVFAYMVICSQILKCWEKQMDHSDAFYFTFITLTTIGFGDIVP----------EHPKFFMVTFLFIITGMAIMSMAFKLGQSQIVCFYRRCIKSLSM 379

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Match: kcnk1a (potassium channel, subfamily K, member 1a [Source:ZFIN;Acc:ZDB-GENE-070620-26])

HSP 1 Score: 70.4774 bits (171), Expect = 1.668e-12
Identity = 67/274 (24.45%), Postives = 112/274 (40.88%), Query Frame = 2

Query: 1121 KTEFPNKDSDVINGKIKYLILSVFNATRNGY-VFN---GNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKP-EFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYW-DGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIF---CAFYLVTGL 1915
            K +F   +  + N +++  ++    A+  G  V N    N  W F+ AL ++ T+++T GYGH VP +  G+   I+Y+++GIP  LL LT +                                       QR    +  +P EF++          ++  T+KP + +   +L                       L +  +  + L+ A +FS   + W F ES YF FI+L+TIG GD VP     GE    + + ++     FYL+ GL
Sbjct:   60 KQQFLEDNECLSNDRLEEFLIKALEASNYGVSVLNNASSNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVVGIPFTLLFLTAV--------------------------------------VQRIMEFSTRRPIEFLH----------RRWGTSKPLLAAMHATL-----------------------LAIITVSCFFLIPAIIFSVLEEEWNFLESFYFCFISLSTIGLGDYVP-----GEGYHQRFRELYKLGITFYLILGL 257

[Close]

Query: 1121 KTEFPNKDSDVINGKIKYLILSVFNATRNGY-VFN---GNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKP-EFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYW-DGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIF---CAFYLVTGL 1915
            K +F   +  + N +++  ++    A+  G  V N    N  W F+ AL ++ T+++T GYGH VP +  G+   I+Y+++GIP  LL LT +                                       QR    +  +P EF++          ++  T+KP + +   +L                       L +  +  + L+ A +FS   + W F ES YF FI+L+TIG GD VP     GE    + + ++     FYL+ GL
Sbjct:   60 KQQFLEDNECLSNDRLEEFLIKALEASNYGVSVLNNASSNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVVGIPFTLLFLTAV--------------------------------------VQRIMEFSTRRPIEFLH----------RRWGTSKPLLAAMHATL-----------------------LAIITVSCFFLIPAIIFSVLEEEWNFLESFYFCFISLSTIGLGDYVP-----GEGYHQRFRELYKLGITFYLILGL 257

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Match: KCNK18 (potassium two pore domain channel subfamily K member 18 [Source:HGNC Symbol;Acc:HGNC:19439])

HSP 1 Score: 92.4337 bits (228), Expect = 1.455e-19
Identity = 82/283 (28.98%), Postives = 132/283 (46.64%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYR---FTCFKVYIKSR--------KRKECKQKLLDSQNNQRKRSGNQNKPEFIN---------------------ILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEE---VDVPIWLPLTILGLYILVGAAVFSYW-DGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEE 1975
            W+F  +L +  T+ TT+GYGHI P T  G+   +VYA +GIPLMLL L +LG ++A L    Y+     C K+  K +        K    K  LL + +++       N  E I                      I+ EN   +  K +  + +     + L   + + M +  +I EE   +DVPI L + ++  YI+ GA +   W D WT  ++ YF F+TLTTIGFGD++P         +     +  + Y V G+ +  M F L Q ++  ++++
Sbjct:   66 WSFKSSLFFCCTVFTTVGYGHICPVTMYGKLACMVYATLGIPLMLLLLADLGDILARLLSRTYKRAVLACNKLCHKPKPIKLSSLHKEHSGKSSLLKTMDSRVSMKEPLNITEVIKTQASVKRKYLQMRNIDIFELIIVKENQKVLPLKSSLQQKSFSCPDLDLWPPSDSAMQNFDKIGEELDHLDVPIVLIVLVMVAYIMCGACILPLWEDDWTTIDAFYFCFVTLTTIGFGDIIP---------KHPNYFLLLSAYTVVGMVIVCMAFKLGQNRLVSFYKQ 339

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Match: pole4 (polymerase (DNA-directed), epsilon 4, accessory subunit [Source:Xenbase;Acc:XB-GENE-5722002])

HSP 1 Score: 66.2402 bits (160), Expect = 9.098e-11
Identity = 35/74 (47.30%), Postives = 44/74 (59.46%), Query Frame = 2

Query: 1733 VGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
            +GAA FSY++GWTFF S Y+ FITLTTIGFGD V     L +    Q K  + AF   Y++ GL V      L+
Sbjct:  185 IGAAAFSYFEGWTFFHSYYYCFITLTTIGFGDFVA----LQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLV 254

HSP 2 Score: 54.6842 bits (130), Expect = 3.989e-7
Identity = 29/72 (40.28%), Postives = 47/72 (65.28%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYR--FTCFKV 1444
            W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+ M    +F+ +    CF++
Sbjct:   90 WKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLKKLKRCFRL 161

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Match: pole4 (polymerase (DNA-directed), epsilon 4, accessory subunit [Source:Xenbase;Acc:XB-GENE-5722002])

HSP 1 Score: 65.0846 bits (157), Expect = 1.975e-10
Identity = 35/74 (47.30%), Postives = 44/74 (59.46%), Query Frame = 2

Query: 1733 VGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
            +GAA FSY++GWTFF S Y+ FITLTTIGFGD V     L +    Q K  + AF   Y++ GL V      L+
Sbjct:  174 IGAAAFSYFEGWTFFHSYYYCFITLTTIGFGDFV----ALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLV 243

HSP 2 Score: 53.9138 bits (128), Expect = 5.744e-7
Identity = 29/72 (40.28%), Postives = 47/72 (65.28%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYR--FTCFKV 1444
            W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+ M    +F+ +    CF++
Sbjct:   79 WKFTGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLKKLKRCFRL 150

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Match: pole4 (polymerase (DNA-directed), epsilon 4, accessory subunit [Source:Xenbase;Acc:XB-GENE-5722002])

HSP 1 Score: 64.6994 bits (156), Expect = 2.937e-10
Identity = 35/74 (47.30%), Postives = 44/74 (59.46%), Query Frame = 2

Query: 1733 VGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
            +GAA FSY++GWTFF S Y+ FITLTTIGFGD V     L +    Q K  + AF   Y++ GL V      L+
Sbjct:  194 IGAAAFSYFEGWTFFHSYYYCFITLTTIGFGDFV----ALQKNEALQKKPPYVAFSFMYILVGLTVIGAFLNLV 263

HSP 2 Score: 53.9138 bits (128), Expect = 6.254e-7
Identity = 29/72 (40.28%), Postives = 47/72 (65.28%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYR--FTCFKV 1444
            W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+ M    +F+ +    CF++
Sbjct:   99 WKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFLLKKLKRCFRL 170

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Match: tbc1d1 (TBC1 domain family member 1 [Source:Xenbase;Acc:XB-GENE-5959648])

HSP 1 Score: 62.3882 bits (150), Expect = 1.743e-9
Identity = 32/76 (42.11%), Postives = 46/76 (60.53%), Query Frame = 2

Query: 1727 ILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
            + +GAA FS+++ W+FF+S Y+ FITLTTIGFGD V     L +    Q K ++ AF   Y++ GL V      L+
Sbjct:  270 LCIGAAAFSHYEDWSFFQSYYYCFITLTTIGFGDYVA----LQKNRALQKKPLYVAFSFMYILVGLTVIGAFLNLV 341

HSP 2 Score: 53.9138 bits (128), Expect = 6.475e-7
Identity = 27/69 (39.13%), Postives = 44/69 (63.77%), Query Frame = 2

Query: 1220 NGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYR 1426
               + W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+ M    K++ +
Sbjct:  172 RAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVKYLLK 240

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Match: Kcnk18 (potassium channel, subfamily K, member 18 [Source:MGI Symbol;Acc:MGI:2685627])

HSP 1 Score: 98.9821 bits (245), Expect = 1.220e-21
Identity = 82/286 (28.67%), Postives = 140/286 (48.95%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFT---CFKVYI-KSRKRKECKQK---------------------LLDSQNNQRKRSGNQNKPEFINILS-------ENPSSILKKENTTKPTMHSFRMSLP-LGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESC-YFVFITLTTIGFGDLV---PGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEEL 1978
            W+F  AL +  T+ +T+GYGH+ P T  G+FL ++YA+ GIPLM L LT++G ++A +    Y RF    C    I K R    C+++                     LL+ Q ++   S + N   F  +++       + P+  +++ N+  P +   R+S   L N   +D V +  E +D+P+ +   ++  YI   AA+  +W+    FE   YF F+TLTTIGFGD+V   P  F            +F + Y++ G+ +  + F L+Q ++   ++ L
Sbjct:  112 WSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIGDILATILSRAYSRFQALLCLPHDIFKWRSLPLCRKQPDSKPVEEAIPQIVIDAGVDELLNPQPSKDPPSPSCNVELFERLVAREKKNKLQPPTRPVERSNSC-PELVLGRLSCSILSN---LDEVGQQVERLDIPLPVIALVVFAYISCAAAILPFWETELGFEDAFYFCFVTLTTIGFGDIVLVHPHFF------------LFFSIYIIVGMEILFIAFKLMQNRLLHTYKTL 381

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Match: Kcnk9 (potassium channel, subfamily K, member 9 [Source:MGI Symbol;Acc:MGI:3521816])

HSP 1 Score: 70.8626 bits (172), Expect = 1.744e-12
Identity = 67/245 (27.35%), Postives = 96/245 (39.18%), Query Frame = 2

Query: 1220 NGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
               + W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+          R   F  Y+  R +K C  +                            ++ +  EN       S   +L LG A F                                 S  + W+FF + Y+ FITLTTIGFGD V     L  K   Q K  + AF   Y++ GL V      L+
Sbjct:   73 RAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE----------RMNTFVRYLLKRIKKCCGMR----------------------------NTEVSMENMVTVGFFSCMGTLCLGAAAF---------------------------------SQCEDWSFFHAYYYCFITLTTIGFGDFVA----LQAKGALQRKPFYVAFSFMYILVGLTVIGAFLNLV 242

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Match: Kcnk3 (potassium channel, subfamily K, member 3 [Source:MGI Symbol;Acc:MGI:1100509])

HSP 1 Score: 64.3142 bits (155), Expect = 2.683e-10
Identity = 34/76 (44.74%), Postives = 47/76 (61.84%), Query Frame = 2

Query: 1727 ILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
            + +GAA FSY++ WTFF++ Y+ FITLTTIGFGD V     L +    QT+  + AF   Y++TGL V      L+
Sbjct:  171 LCIGAAAFSYYERWTFFQAYYYCFITLTTIGFGDYV----ALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLV 242

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Match: Kcnk4 (potassium channel, subfamily K, member 4 [Source:MGI Symbol;Acc:MGI:1298234])

HSP 1 Score: 60.8474 bits (146), Expect = 3.403e-9
Identity = 33/89 (37.08%), Postives = 46/89 (51.69%), Query Frame = 2

Query: 1721 LYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKR 1987
            L++L    VFSY + W+  E+ YFV +TLTT+GFGD VPG+   G             F+++ GLA FA   T I      W   + +R
Sbjct:  183 LFVLTPTFVFSYMESWSKLEAIYFVIVTLTTVGFGDYVPGD---GTGQNSPAYQPLVWFWILFGLAYFASVLTTI----GNWLRAVSRR 264

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Match: Kcnk10 (potassium channel, subfamily K, member 10 [Source:MGI Symbol;Acc:MGI:1919508])

HSP 1 Score: 60.4622 bits (145), Expect = 5.419e-9
Identity = 33/89 (37.08%), Postives = 51/89 (57.30%), Query Frame = 2

Query: 1721 LYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKR 1987
            +++ + A +F Y +GWT  ES YFV +TLTT+GFGD V G    G   ++  K +   F+++ GLA FA   ++I     +W   L K+
Sbjct:  229 VFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGG-NAGINYREWYKPLVW-FWILVGLAYFAAVLSMI----GDWLRVLSKK 311

[Close]

BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Match: sp|Q7Z418|KCNKI_HUMAN (Potassium channel subfamily K member 18 OS=Homo sapiens OX=9606 GN=KCNK18 PE=1 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 3.022e-23
Identity = 81/282 (28.72%), Postives = 134/282 (47.52%), Query Frame = 2

Query: 1217 FNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENP--------------------SSILKKENTTKPTMHSFRMS-----LPLGNANF-----MDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESC-YFVFITLTTIGFGDLV---PGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKV 1957
            FN    W+F  +L +  T+ +T+GYG+I P T  G++L ++YA+ GIPLM L LT+ G ++A +    Y RF  F  + +    K C + L   + +   +  ++  P+ I    E P                    S  L+K+NT +    +   S     L LG  ++     +D V +  E +D+P+ +   I+  YI   AA+  +W+    FE+  YF F+TLTTIGFGD V   P  F            +F + Y++ G+ +  + F L+Q ++
Sbjct:   95 FNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNRFRKFPFFTRPLLSKWCPKSLFKKKPD--PKPADEAVPQIIISAEELPGPKLGTCPSRPSCSMELFERSHALEKQNTLQLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHPNFF------------LFFSIYIIVGMEIVFIAFKLVQNRL 362

[Close]

BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Match: sp|Q6Q1P3|KCNKI_RAT (Potassium channel subfamily K member 18 OS=Rattus norvegicus OX=10116 GN=Kcnk18 PE=2 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 1.247e-22
Identity = 82/288 (28.47%), Postives = 137/288 (47.57%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCF----------KVYIKSRKRKECK---------------QKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMS-----LPLGNANF-----MDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESC-YFVFITLTTIGFGDLV---PGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEEL 1978
            W+F  AL +  T+ +T+GYGH+ P T  G+FL ++YA+ GIPLM L LT++G ++A +    Y RF             +  +  RK+ + K                +LLD Q ++   S + N   F  +++       +K+N  +P M     S     L LG  +      +D V +  E +D+P+ +   ++  YI   AA+  +W+    FE   YF F+TLTTIGFGD+V   P  F            +F + Y++ G+ +  + F L+Q ++   ++ L
Sbjct:  123 WSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIGDILAAILSRAYSRFQALLCLPRDISKWRPLLLCRKQTDSKPADEAIPQIVIDAGADELLDPQPSREPASPSCNVELFERLVAR------EKQNELQPPMRPVERSNSCPELVLGRLSCSILSNLDEVGQQVERLDIPLPVIALVIFAYISCAAAILPFWETDLGFEDAFYFCFVTLTTIGFGDIVLVHPHFF------------LFFSIYIIVGMEILFIAFKLMQNRLLHTYKTL 392

[Close]

BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Match: sp|Q6VV64|KCNKI_MOUSE (Potassium channel subfamily K member 18 OS=Mus musculus OX=10090 GN=Kcnk18 PE=1 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 8.535e-21
Identity = 82/286 (28.67%), Postives = 140/286 (48.95%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFT---CFKVYI-KSRKRKECKQK---------------------LLDSQNNQRKRSGNQNKPEFINILS-------ENPSSILKKENTTKPTMHSFRMSLP-LGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESC-YFVFITLTTIGFGDLV---PGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEEL 1978
            W+F  AL +  T+ +T+GYGH+ P T  G+FL ++YA+ GIPLM L LT++G ++A +    Y RF    C    I K R    C+++                     LL+ Q ++   S + N   F  +++       + P+  +++ N+  P +   R+S   L N   +D V +  E +D+P+ +   ++  YI   AA+  +W+    FE   YF F+TLTTIGFGD+V   P  F            +F + Y++ G+ +  + F L+Q ++   ++ L
Sbjct:  112 WSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIGDILATILSRAYSRFQALLCLPHDIFKWRSLPLCRKQPDSKPVEEAIPQIVIDAGVDELLNPQPSKDPPSPSCNVELFERLVAREKKNKLQPPTRPVERSNSC-PELVLGRLSCSILSN---LDEVGQQVERLDIPLPVIALVVFAYISCAAAILPFWETELGFEDAFYFCFVTLTTIGFGDIVLVHPHFF------------LFFSIYIIVGMEILFIAFKLMQNRLLHTYKTL 381

[Close]

BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Match: sp|Q18120|TWK18_CAEEL (TWiK family of potassium channels protein 18 OS=Caenorhabditis elegans OX=6239 GN=twk-18 PE=1 SV=2)

HSP 1 Score: 97.8265 bits (242), Expect = 3.448e-20
Identity = 72/250 (28.80%), Postives = 120/250 (48.00%), Query Frame = 2

Query: 1217 FNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRK--RKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVK 1960
             + +I WTF G++ Y +T+ TTIGYG+IVP T  GRF TI+YA IGIPL +L L  LG + A   K ++RF     ++KS +   K+   K+ ++ +N                + E  ++I      T+       +S P+                       L I  ++++  A +F++ + W F  S YF  I+ TTIGFGD++P +++                 L+ GL++ +   TLIQ++++
Sbjct:  108 MDKDIHWTFLGSIFYCMTVYTTIGYGNIVPGTGWGRFATILYAFIGIPLTVLSLYCLGSLFAKGCKMLWRF-----FLKSTRVVSKDLSNKISEAADN----------------IEEGTTAITPSAEKTENNDDDL-LSFPISGL--------------------LLITVIWVIFCAVLFTFLEEWDFGTSLYFTLISFTTIGFGDILPSDYDFMP---------IVGVLLLIGLSLVSTVMTLIQQQIE 306

[Close]

BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Match: sp|P34410|TWK7_CAEEL (TWiK family of potassium channels protein 7 OS=Caenorhabditis elegans OX=6239 GN=twk-7 PE=3 SV=3)

HSP 1 Score: 90.1225 bits (222), Expect = 2.025e-17
Identity = 63/203 (31.03%), Postives = 102/203 (50.25%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEIS-EEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVP 1837
            WTFS ++ +++T++TTIGYG+ VP T  GR   I+++++GIPL L+ + +LGK +++   ++Y  +   K  I SR RKE ++ + +                                       HS  M             H+++ EE  +P +L L IL +Y   G  + S  + W+FF S Y+ FIT+TT+GFGDL+P
Sbjct:  265 WTFSSSIFFAVTVVTTIGYGNPVPVTNIGRIWCILFSLLGIPLTLVTIADLGKFLSEHLVWLYGNYLKLKYLILSRHRKERREHVCEH-------------------------------------CHSHGMG------------HDMNIEEKRIPAFLVLAILIVYTAFGGVLMSKLEPWSFFTSFYWSFITMTTVGFGDLMP 418

[Close]

BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Match: G4V9R5 (Twik family of potassium channels-related OS=Schistosoma mansoni OX=6183 GN=Smp_127170 PE=3 SV=1)

HSP 1 Score: 190.66 bits (483), Expect = 1.435e-48
Identity = 112/295 (37.97%), Postives = 167/295 (56.61%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQ------------KLLDSQNNQRKRSGNQNKPEFIN--ILSENPSSILKKEN-----TTKPTMHSFRMSLPLGNANFMDSVHEI---------------------SEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI 1999
            WT +GALLY++T+ITTIGYGHIVPKT  GR +T++YA+ GIPL+LLCLTNLG  +A+  + +Y  +CFK +    K+K  KQ            K+L + + ++     + KP  ++  I     +SI+   N     T+K +++   M+     A F      I                     ++ V VPIWL L +  +Y++VGA +F+ W+ W   +S YFVFITL+TIGFGD VPG  +  +  ++ TK +FC FYL+ GL++ AM F L+QE+VK  F     ++GL+
Sbjct:  264 WTLTGALLYAVTVITTIGYGHIVPKTDLGRAITVIYALFGIPLVLLCLTNLGGFLANTVRIIYSNSCFKYHEHRVKKKLSKQHIQSILPVIRDEKILPNSSKRKLLPNRKTKPSKLHNTIQETTETSIVNNYNDSNKYTSKESINQLHMN-DYHTARFEKRAQSILHTLTSSQSIISSGIQKEKRKNKGVHVPIWLTLLVFFIYMIVGAIIFAKWENWNLLQSGYFVFITLSTIGFGDFVPG-IQTDKWQENSTKPVFCCFYLLFGLSMVAMSFNLMQEEVKTKFRRFAYKVGLV 556

[Close]

BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Match: T1IJW1 (Uncharacterized protein OS=Strigamia maritima OX=126957 PE=3 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 3.093e-47
Identity = 107/255 (41.96%), Postives = 146/255 (57.25%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI 1999
            W+FSGALLYS+T+ITTIGYG+I PKT  G+ +T++YA+IGIPLMLLCLTN+G   A  FKF Y   C K+         C ++  D    +   + NQ         +E  S + KKEN  +  ++  +M++                   VPIWL +TI+  YI +GA +F+ W+GWT     YF FITL+TIGFGDLVPG     +    Q K I C  YLV GLA+ AM F L+QE+V    + + + IG++
Sbjct:  120 WSFSGALLYSVTVITTIGYGNISPKTEKGKVVTMLYAVIGIPLMLLCLTNIGDFFAKAFKFAYAKICCKL---------CLEQQPDHSTKKTPSTDNQ---------TEGCSYVGKKENE-EIAVNEEQMTVQ-----------------RVPIWLVMTIVSSYIGIGATIFTLWEGWTPLNGAYFCFITLSTIGFGDLVPGTTFDTDTGGGQAKLIICCLYLVLGLAIIAMAFNLVQEEVVAKCKHIARNIGML 338

[Close]

BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Match: A0A210QTX8 (TWiK family of potassium channels protein 18 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT15723 PE=3 SV=1)

HSP 1 Score: 183.341 bits (464), Expect = 1.046e-46
Identity = 108/279 (38.71%), Postives = 163/279 (58.42%), Query Frame = 2

Query: 1187 VFNATR----NGYVFNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKS-QDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI*SE 2008
            ++ AT+    +G    G + W+F+GALLYSIT+ITTIGYGHI PKT +GR +T+VYA+ GIPL LLCL N+G  +A+ F+F+Y+  C  V           Q     Q++ R ++  + + + I              ++ K  +H   +++ +G+     + +  +E+V VPI + L ++  YI  GA +F+ W+GW +    YF FITL+T+GFGD VPG    G  S  +  K I CAFYL+ GL++ AMCF L+QE+V+  F  LG + G+I  E
Sbjct:  224 IYKATKENGWDGKDGEGEVQWSFAGALLYSITVITTIGYGHIAPKTANGRMVTVVYALFGIPLTLLCLANMGSFLANCFRFLYKNVCLAVIWLCCP----SQAKWHRQSDSRIKTPTKEEADLI-------------RSSKKGELHD-EVTIVIGDKT--SNTNNKNEKVRVPILVSLMLIAAYIFGGATLFAMWEGWDYLVGSYFCFITLSTVGFGDFVPG---AGVYSFSNNQKLIICAFYLIFGLSLIAMCFELMQEEVRAKFRWLGLKCGIIDDE 479

HSP 2 Score: 64.3142 bits (155), Expect = 7.289e-7
Identity = 31/73 (42.47%), Postives = 48/73 (65.75%), Query Frame = 2

Query:  485 AKQREIRRQKCIRCCKQSIAFFFSQIGVMCIVVAYIIAGGFLFQNLEAKNEINISKSGESNINDSLKKLMEKI 703
            AK +  R ++CI+CCKQ +AF FS IG+  +VVAY I GGF+F+ LEA  E    K+  +N+  + K  ++++
Sbjct:  126 AKSQNRRGKRCIKCCKQFVAFLFSHIGMCSLVVAYSILGGFIFKELEAPYE----KTARANVAANRKVQVDRL 194

[Close]

BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Match: T1EJ43 (Uncharacterized protein OS=Helobdella robusta OX=6412 GN=20196593 PE=3 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 2.210e-46
Identity = 106/261 (40.61%), Postives = 151/261 (57.85%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNN--QRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWD-GWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI*SE 2008
            WTF+GALLYSIT+ITTIGYGHI PKT  GR +T++YAI+GIPL L  +TNLG  MA  F+F YR  C ++ +K   ++      L  Q +   +KR    + P+     S +     +K           R  L    ++         ++V VPI++ L I+ +YI +GA +FS W+  W++   CYF FITL+TIGFGD VPG     ++   Q K + CA YL  GLA+ AMCF L+ E+++   +E  K+IGL+ S+
Sbjct:  112 WTFAGALLYSITVITTIGYGHIAPKTDWGRIVTMLYAILGIPLTLFTITNLGSFMATAFRFTYRNVCCRLTLKKYNKQTTLHSKLRPQTSPISKKRRKKHHSPQDHVTSSNHDVDDWRK-----------RFDLIFFTSDI--------KQVKVPIYISLLIITIYIALGATLFSLWEKNWSYLIGCYFCFITLSTIGFGDYVPGTSS--DQWNSQAKLVLCALYLFVGLALIAMCFDLMLEQIRSNLKEFAKKIGLLTSD 351

[Close]

BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Match: A0A4Z2DMW5 (Potassium channel subfamily K member 18 OS=Schistosoma japonicum OX=6182 GN=EWB00_010611 PE=3 SV=1)

HSP 1 Score: 187.193 bits (474), Expect = 2.263e-46
Identity = 114/293 (38.91%), Postives = 164/293 (55.97%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQK-------LLDS---QNNQRK-------------------------RSGNQNK---PEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI 1999
            WT +GALLY++T+ITTIGYGHIVPKT  GR  T++YA+ GIPL+LLCL NLG  +A+  + +Y  +C K +    K+K  KQ        L D    Q  +RK                            +QNK    E IN    N    ++ E   +  +H+   S  + ++N M  V + ++EV VP+WL L +  +Y+ VGA +F+ W+ W   +S YFVFITL+TIGFGD VPG  +  +  ++ TK +FC FYL+ GL++ AM F L+QE+V+  F     ++GLI
Sbjct:  445 WTLTGALLYAVTVITTIGYGHIVPKTDLGRATTVIYALFGIPLVLLCLANLGGFLANTVRIIYANSCLKYHEHRVKKKLSKQHTSSILPILKDEDFIQPPKRKLLNRKITNHLTTHTTHDKTEMPTITNYVDQNKYTSKESINKQHINDYHAVRFERRAQSILHTLTSSQSIISSN-MQKVKK-TDEVHVPMWLTLLVFFIYMTVGAIIFANWESWNLLQSAYFVFITLSTIGFGDFVPG-IQTDKWHENSTKPVFCCFYLLFGLSMVAMSFNLMQEEVRAKFRRFASKVGLI 734

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Match: ENSAMXT00000047723.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:15897283:15919205:1 gene:ENSAMXG00000033807.1 transcript:ENSAMXT00000047723.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 99.7525 bits (247), Expect = 1.171e-21
Identity = 84/283 (29.68%), Postives = 127/283 (44.88%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRK-------RSGNQ--NKPEFI---------------NILSENPSSILKKENTTKPTM--HSFRMSLPLGNA-------------------NFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYW-DGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF-YLVTGLAVFAMCFTL 1942
            W F G+L +  T+ TT+GYG I P T +GR   I+YA +GIPLMLL +T++G ++A LF   YR          R    C++ L    N  +K       R G    N+   +               +++ + P  +LK +N     +    FR   PL  +                   +F+   HE+ E  +VP  + L ++  YIL+ A +   W D    F++ YF FITLTTIGFGD+VP             K     F +++ G+A+ +M F L
Sbjct:  223 WHFYGSLFFCCTVFTTVGYGEIYPVTKAGRVACILYATVGIPLMLLVITDVGDILAVLFSNSYR----------RLHSSCRRLLYRVWNPHQKPRDPVTIRDGTYIFNRDVVVQEVSVDHRIGTAIDSSVIEQKPDHLLKNKNIFNHIIAKEKFRRKRPLTRSCSCPELNQMPPPPVGFKIKDFLSIGHEM-ERFNVPFLVILLVVFAYILIWALILPIWEDDLGKFDAFYFCFITLTTIGFGDIVP----------KHPKFFMLTFLFIIMGMAIMSMAFKL 484

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Match: kcnk9 (potassium two pore domain channel subfamily K member 9 [Source:NCBI gene;Acc:103047047])

HSP 1 Score: 76.6406 bits (187), Expect = 2.512e-14
Identity = 66/245 (26.94%), Postives = 100/245 (40.82%), Query Frame = 2

Query: 1220 NGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
               + W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+          R   F  Y+  R +K C  ++ +                            +  EN       S   +L +G A F                                 S+++ W+FF+S Y+ FITLTTIGFGD V     L +    Q K ++ AF   Y++ GL V      L+
Sbjct:  128 RAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE----------RMNTFVKYLLKRIKKCCGMRITE----------------------------VSMENMVTVGFFSCMGTLCIGAAAF---------------------------------SHYEDWSFFQSYYYCFITLTTIGFGDFVA----LQKNRALQRKPLYVAFSFMYILVGLTVIGAFLNLV 297

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Match: kcnk15 (potassium channel subfamily K member 15-like [Source:NCBI gene;Acc:103042097])

HSP 1 Score: 66.6254 bits (161), Expect = 3.670e-11
Identity = 41/94 (43.62%), Postives = 57/94 (60.64%), Query Frame = 2

Query: 1667 EISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF-YLVTGLAVFAMCFTLI 1945
            E+S E  V I   L+ LG  + VGAA FS+++GWTFF + Y+ FITLTTIGFGD V    +  E  Q++T  +  +F Y++ GL V      L+
Sbjct:  153 EVSMENMVLIGF-LSCLGT-LCVGAAAFSHFEGWTFFHAYYYCFITLTTIGFGDFVA--LQKNEDLQEKTPYVVFSFMYILVGLTVIGAFLNLV 242

HSP 2 Score: 53.5286 bits (127), Expect = 4.595e-7
Identity = 27/62 (43.55%), Postives = 42/62 (67.74%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFM 1420
            W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+ M    +F+
Sbjct:   78 WKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVRFL 139

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Match: kcnk2b (potassium channel, subfamily K, member 2b [Source:ZFIN;Acc:ZDB-GENE-051120-69])

HSP 1 Score: 60.077 bits (144), Expect = 4.228e-9
Identity = 33/89 (37.08%), Postives = 53/89 (59.55%), Query Frame = 2

Query: 1721 LYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKR 1987
            L++ + A +F + + W+  ++ YFV ITLTTIGFGD V G  E+  + QD  K +   F+++ GLA FA   ++I     +WF  + K+
Sbjct:  220 LFVTLPAIIFQHIERWSTLDAIYFVVITLTTIGFGDFVAGGSEM--EYQDYYKPVVW-FWILVGLAYFAAVLSMI----GDWFRVISKK 301

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Match: KCNK16 (potassium channel subfamily K member 16 [Source:NCBI gene;Acc:103040539])

HSP 1 Score: 54.6842 bits (130), Expect = 1.406e-7
Identity = 26/62 (41.94%), Postives = 42/62 (67.74%), Query Frame = 2

Query: 1658 SVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGN 1843
            S+H+  E + V ++L +  + L+++    +FSY +GW++ E  Y+ FITL+TIGFGD V GN
Sbjct:  166 SIHQCMEVLAVVVFLLMGSV-LFLIFPPIIFSYVEGWSYGEGFYYAFITLSTIGFGDFVVGN 226

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003416.1 (pep scaffold:Pmarinus_7.0:GL476517:78247:80718:1 gene:ENSPMAG00000003129.1 transcript:ENSPMAT00000003416.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 101.293 bits (251), Expect = 2.009e-24
Identity = 65/208 (31.25%), Postives = 115/208 (55.29%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSR-KRKECKQKLLDSQNNQRKRSG------NQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVP 1837
            W F G+L +  TI TTIGYGHI P T  G+ + +VYA  GIP+MLL L ++G ++A     +Y     ++   +R  R+       +  + QR R+       ++ + + +++  ++P S ++       T+     S+  G A+  ++  E+ +E+DVP  L   I+ +Y++ G  +   W+ W++ ++ YFVF+T+TTIG GD+VP
Sbjct:    2 WNFLGSLFFCCTIFTTIGYGHIAPSTDGGKIMCMVYATFGIPIMLLVLADVGDLLARTLTTIYTSFRHRLLPGARCGRQHPPGDGPEGNDLQRSRTKIDDSHRHEGEDDAVDVPLKSPGSDVEGGRELPATV-----SIAEG-ADVPEADREV-KELDVPFTLIFLIVFVYLMFGTFLLPCWEEWSYLDAFYFVFVTMTTIGLGDIVP 202

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Match: kcnk7 (potassium channel, subfamily K, member 7 [Source:ZFIN;Acc:ZDB-GENE-110304-2])

HSP 1 Score: 51.2174 bits (121), Expect = 3.688e-7
Identity = 28/65 (43.08%), Postives = 42/65 (64.62%), Query Frame = 2

Query: 1193 NATRNGYVFNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNL 1387
            +A RN         W F  AL ++ T++TT+GYGH VP + +G+ L I+YA++GIP  LL LT++
Sbjct:   77 SALRNA---TAGPHWDFVSALFFASTVLTTVGYGHTVPLSDAGKALCILYAVLGIPFTLLLLTSI 138

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Match: KCNK10 (potassium two pore domain channel subfamily K member 10 [Source:HGNC Symbol;Acc:HGNC:6273])

HSP 1 Score: 50.8322 bits (120), Expect = 5.233e-7
Identity = 34/121 (28.10%), Postives = 64/121 (52.89%), Query Frame = 2

Query: 1718 GLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI*SESNRINSFQDIR*QIEHFFGRISNR 2080
            GL++++   +F + + WT  E+ YFV ITLTTIGFGD V G     +    +       F+++ G+A FA   ++I + +++  E+    +G I + +++  +  D +     F G I ++
Sbjct:  195 GLFVVLPTIIFMHIELWTPLEAIYFVVITLTTIGFGDYVAGGNR--DIVYREWYKPLVWFWILLGMAYFAAILSMIGDWLRKLSEKTRNEMGGITAHASQWTA--DFKESGSRFTGGIHDK 311

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Match: kcnk13a (potassium channel, subfamily K, member 13a [Source:ZFIN;Acc:ZDB-GENE-080219-46])

HSP 1 Score: 50.8322 bits (120), Expect = 8.538e-7
Identity = 53/211 (25.12%), Postives = 87/211 (41.23%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRF-TCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILV----GAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFEL 1852
            W F+GA  +  T+++TIG+G   P T SG+   I Y + G    +L   NL         F+ R  T     ++S  R++  + ++      RK S   +  E +                                A +  SV+ +           + ILG+  +      +A+FS  +GW++ +S YF F+  +TIGFGDLV G  +L
Sbjct:  115 WDFTGAFYFVGTVVSTIGFGMTTPTTVSGKIFLIFYGLFGCAAGIL-FFNL---------FLERLITLLACVMRSCHRRQINRLVIQPG---RKASDQSDAIECL--------------------------------AGWKPSVYHV-----------MMILGIAAVAIACSASAMFSAVEGWSYVDSLYFCFVAFSTIGFGDLVTGQRDL 269

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Match: KCNK16 (potassium two pore domain channel subfamily K member 16 [Source:HGNC Symbol;Acc:HGNC:14464])

HSP 1 Score: 48.521 bits (114), Expect = 2.391e-6
Identity = 27/71 (38.03%), Postives = 43/71 (60.56%), Query Frame = 2

Query: 1724 YILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCF 1936
            ++L+  AV    +GW+  +S Y+ FITL+TIGFGDLV G+ E G +     +++  A ++V  LA  A  +
Sbjct:  177 FVLLPVAVLPVTEGWSHAKSLYYAFITLSTIGFGDLVVGS-EPGREYVAGYRTLVAA-WIVASLACLAATY 245

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Yeast
Match: TOK1 (Outward-rectifier potassium channel of the plasma membrane; has two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin [Source:SGD;Acc:S000003629])

HSP 1 Score: 51.9878 bits (123), Expect = 2.717e-7
Identity = 50/214 (23.36%), Postives = 88/214 (41.12%), Query Frame = 2

Query: 1214 VFNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCL----TNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKK--ENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVP 1837
            +F+G +  T+  AL +    + T+G G I+PK+   + + +++++ G+ LM L +    + + K    +F F +R          + R +  +  +DS  N                LSE  +  L K    T     H F +S+ +                         I   + L+GA VF + + W++F   YF F+ L TIG+GD  P
Sbjct:  265 MFSGLLHITYGNALYFCTVSLLTVGLGDILPKSVGAKIMVLIFSLSGVVLMGLIVFMTRSIIQKSSGPIF-FFHRV--------EKGRSKSWKHYMDSSKN----------------LSEREAFDLMKCIRQTASRKQHWFSLSVTIA------------------------IFMAFWLLGALVFKFAENWSYFNCIYFCFLCLLTIGYGDYAP 429

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Match: EDO48564 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIT3])

HSP 1 Score: 70.0922 bits (170), Expect = 4.878e-13
Identity = 47/203 (23.15%), Postives = 89/203 (43.84%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGN 1843
            W+ + + L++ T+ TT+GYG+I P T  GR   ++Y  +GIPL  +   +L   + ++   +++                       + ++RKR                 +++ KK++   P                     E   E+++ +     ++  Y+ +GA +F   +GW+ FES Y+ FITL+T+G GD VP +
Sbjct:  126 WSLADSWLFACTVFTTVGYGNIAPLTIKGRVFCMLYGAVGIPLFSVVAGSLASFVTEIIHALHK-----------------------EYHRRKR--------------HESAAMHKKDDVIAPD--------------------EPVPELEIKLKHVAVVVAGYLCIGAVLFCICEGWSLFESFYYCFITLSTVGLGDYVPQH 271

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Match: EDO35592 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL44])

HSP 1 Score: 67.3958 bits (163), Expect = 1.562e-12
Identity = 59/229 (25.76%), Postives = 96/229 (41.92%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQT-KSIFCAFYLVTGLA 1918
            W F  A  ++ T+ITTIGYG+I P +  G+   IVYA+ GIP+  + LT +                             ++ LL ++  Q   +G+         +   P+S L+  + T                                 ++ L +L   + V A VF   +GW +FE+ YF FI+LTTIG GD VPG+  + + S  ++   + C  + + GL+
Sbjct:   76 WEFGSAFFFAGTVITTIGYGNIAPLSSGGKIFCIVYALFGIPMTAIMLTAI----------------------------VERLLLAAERVQELMAGSCT-------VRGIPASYLRMVHLT---------------------------------FIMLVVLMFIMFVPALVFMNLEGWNYFEAFYFCFISLTTIGLGDFVPGDDVMWQHSAYRSLYKVCCILFFIIGLS 236

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Match: EDO34988 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMS2])

HSP 1 Score: 60.077 bits (144), Expect = 3.410e-11
Identity = 52/183 (28.42%), Postives = 72/183 (39.34%), Query Frame = 2

Query: 1286 GYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLV 1834
            GYG I P+T +G+  TI YA+IGIPL LL L ++G V  + F F          I+S  RK CK +                     N L +N S +L                                          LT++    +V   +F     WTF E+ YFVF++ +T+GFGD V
Sbjct:    1 GYGSITPRTQAGQLTTIAYALIGIPLTLLTLRSVG-VHINAFHFY--------LIRSTHRKHCKNE---------------------NALMKNTSGLL------------------------------------------LTVI----IVAVVMFFSVTSWTFTEAFYFVFVSCSTVGFGDYV 107

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Match: EDO38072 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE00])

HSP 1 Score: 63.1586 bits (152), Expect = 5.269e-11
Identity = 55/206 (26.70%), Postives = 80/206 (38.83%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLF----KFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTI-LGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVP 1837
            W F GA  ++   + T+GYG I+P+T  GR LTI+Y ++G+PL ++ L   G+ +  L      F Y  TC                                                     T P+ HS R  L              +  + V ++L L   LG+Y+          + W+F +S Y  FIT +TIGFGDLVP
Sbjct:   33 WDFLGACAFTFAALLTVGYGDIIPETPIGRGLTIIYCLVGLPLSVMALKTGGEAVVHLISSTEAFFYSRTC----------------------------------------------------GTPPSPHSLRRCLA-------------TSVILVTVYLCLMAGLGMYL----------EEWSFLDSFYAWFITFSTIGFGDLVP 163

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Match: EDO47668 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLC5])

HSP 1 Score: 60.4622 bits (145), Expect = 6.053e-10
Identity = 29/57 (50.88%), Postives = 44/57 (77.19%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMAD 1405
            W+++G+L +S T+ITTIGYGH+ P+TF GR   ++YA+ GIP+  L LT+LGK + +
Sbjct:   86 WSYTGSLFFSGTVITTIGYGHLSPETFFGRIFCMLYALFGIPITWLMLTSLGKKIVE 142

HSP 2 Score: 53.1434 bits (126), Expect = 1.351e-7
Identity = 31/80 (38.75%), Postives = 45/80 (56.25%), Query Frame = 2

Query: 1700 LPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTK------SIFCAFYLVTGLAV 1921
            + L+ + + I+    +FS  + WTFFE  YF FI+LTTIGFGD VP +  +  K  +++        +FC F    GLAV
Sbjct:  172 IGLSFVVMVIVAIVGIFS--ENWTFFEGFYFAFISLTTIGFGDYVPLHPNVDHKDIEKSSFRISLFVLFCMFLFSFGLAV 249

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Match: kcnk18 (potassium two pore domain channel subfamily K member 18 [Source:NCBI gene;Acc:101159039])

HSP 1 Score: 93.9745 bits (232), Expect = 4.083e-20
Identity = 79/290 (27.24%), Postives = 135/290 (46.55%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADL-----------FKFMYRFTCFKVYIKSRKRKECKQKL----------------LDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTK--PTMHSFRM----SLPLGNANFM----DSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWD-GWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRI 1990
            WTF G++ +  T+ TT+GYG I P T SG+ + ++YA++GIPLMLL + ++G  +A L           FK +   T      + R     +Q L                LD +   R ++  ++K   +    E    IL ++N  +  P + +F       LP     F+      + +  +++DVP  L L  +  YI +G  +   W+  +T F+  YF FITLTTIGFGD++P         +     +  + +++ G+A+ +M F L Q ++   + +  K I
Sbjct:  101 WTFFGSMFFCCTVFTTVGYGEIYPVTLSGKVVCVLYAMVGIPLMLLVILDVGDFLALLMTKAYVQAHAFFKDLRSQTWSPGKAQDRASDSRRQGLDDGTFVFSRDVVALEPLDIRQVLRSQADVRHKSIQLQNNKEIFEKILARDNLQRKGPLLRTFSCPELNQLPTPPKGFIVWDFTGLGDGMDQLDVPFVLILFAVFAYICLGGLILPLWEKDFTDFDPYYFCFITLTTIGFGDIIP---------KHPNYFMLISLFIIVGMAIMSMAFKLSQTRIVTCYRKCIKFI 381

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Match: kcnk15 (potassium channel subfamily K member 15 [Source:NCBI gene;Acc:101160319])

HSP 1 Score: 67.3958 bits (163), Expect = 2.194e-11
Identity = 41/96 (42.71%), Postives = 58/96 (60.42%), Query Frame = 2

Query: 1667 EISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
            E+S E  V + L L+ +G  + VGAA FS+++GW+FF + Y+ FITLTTIGFGD V     L +K   Q K+ + AF   Y++ GL V      L+
Sbjct:  158 EVSMENMVLVGL-LSCVGT-LCVGAAAFSHFEGWSFFHAYYYCFITLTTIGFGDFVA----LQKKEDLQEKTPYVAFSFMYILVGLTVIGAFLNLV 247

HSP 2 Score: 53.1434 bits (126), Expect = 7.293e-7
Identity = 27/62 (43.55%), Postives = 41/62 (66.13%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFM 1420
            W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+ M     F+
Sbjct:   83 WKFAGSFYFAITVITTIGYGHAAPGTDAGKVFCMFYAVLGIPLTLVMFQSLGERMNTFVHFL 144

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Match: kcnk3a (potassium two pore domain channel subfamily K member 3 [Source:NCBI gene;Acc:101167669])

HSP 1 Score: 67.0106 bits (162), Expect = 2.269e-11
Identity = 33/74 (44.59%), Postives = 46/74 (62.16%), Query Frame = 2

Query: 1727 ILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQD-QTKSIFCAFYLVTGLAVFAMCFTLI 1945
            +  GA  FS+++GWTFF++ Y+ FITLTTIGFGD V    + GE  Q+ Q   +FC  Y++ GL V      L+
Sbjct:  171 LCAGALAFSHFEGWTFFQAYYYCFITLTTIGFGDYVA--LQKGEALQEKQGYVVFCFIYILMGLGVIGAFLNLV 242

HSP 2 Score: 50.0618 bits (118), Expect = 6.413e-6
Identity = 25/62 (40.32%), Postives = 42/62 (67.74%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFM 1420
            W F+G+  ++IT+ITTIGYGH  P T  G+   ++YA++GIPL L+   +LG+ +    +++
Sbjct:   78 WNFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMLYALLGIPLTLVMFQSLGERINTFVRYL 139

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Match: ENSORLT00000013824.2 (potassium channel subfamily K member 2-like [Source:NCBI gene;Acc:101168108])

HSP 1 Score: 65.855 bits (159), Expect = 7.024e-11
Identity = 36/89 (40.45%), Postives = 53/89 (59.55%), Query Frame = 2

Query: 1721 LYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKR 1987
            L++ + AA+F + +GW+  ES YFV ITLTTIGFGD V G  E+  +  D  K +   F+++ GLA FA   ++I     +W   + KR
Sbjct:  232 LFVALPAAIFKHIEGWSALESLYFVVITLTTIGFGDFVAGGSEI--EYLDYYKPVVW-FWILVGLAYFAAILSMI----GDWLRVISKR 313

HSP 2 Score: 50.0618 bits (118), Expect = 5.504e-6
Identity = 36/103 (34.95%), Postives = 58/103 (56.31%), Query Frame = 2

Query: 1118 DKTEFPNKDSDVINGKIKYLILSVFNATRNGY-----VFNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLF 1411
             K +F +K S V   +++ +  +V +A R+G      + N + LW  S A  ++ T+ITTIG+G+I P T  G+   IVYA++GIPL    L  +G  +  +F
Sbjct:   98 QKLKFLSKHSCVNQSQLEEI--NVVSAMRSGVNPVGTLTNHSSLWDLSSAFFFAGTVITTIGFGNISPHTEGGKIFCIVYALLGIPLFGFLLAGVGDQLGTIF 198

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Match: kcnk9 (potassium two pore domain channel subfamily K member 9 [Source:NCBI gene;Acc:101171424])

HSP 1 Score: 62.7734 bits (151), Expect = 4.811e-10
Identity = 32/76 (42.11%), Postives = 46/76 (60.53%), Query Frame = 2

Query: 1727 ILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAF---YLVTGLAVFAMCFTLI 1945
            + +GAA FS+++ W+FF+S Y+ FITLTTIGFGD V     L +    Q K ++ AF   Y++ GL V      L+
Sbjct:  171 LCIGAAAFSHYEDWSFFQSYYYCFITLTTIGFGDFVA----LQKNRALQKKPLYVAFSFMYILVGLTVIGAFLNLV 242

HSP 2 Score: 54.299 bits (129), Expect = 2.479e-7
Identity = 32/91 (35.16%), Postives = 49/91 (53.85%), Query Frame = 2

Query: 1220 NGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLD 1492
               + W F+G+  ++IT+ITTIGYGH  P T +G+   + YA++GIPL L+   +LG+          R   F  Y+  R +K C   + D
Sbjct:   73 RAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGE----------RMNTFVKYLLKRIKKCCGMSITD 153

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Match: SMESG000031911.1 (SMESG000031911.1)

HSP 1 Score: 1214.91 bits (3142), Expect = 0.000e+0
Identity = 611/614 (99.51%), Postives = 612/614 (99.67%), Query Frame = 2

Query:  158 MIQQRDSINCATNTQLKPAPMALFESIDEEQEYGSNSSLIESKLIRQENNSHNSLPDNEVILNHNRRPPPRKLTITQVPLTEYSRPLDTETNVILDSEQTQNRLKHFFDAKQREIRRQKCIRCCKQSIAFFFSQIGVMCIVVAYIIAGGFLFQNLEAKNEINISKSGESNINDSLKKLMEKIRSSEQETVDKHKSFCKRLIINQSSESNLRLTEFFNVNKKQLNNAIYTLQWNFQDMRTFIQEKITNIQSNLNLTKSSKFVSNNSALVIKDNLIEISNRLWDVGEEIKKLEALQNTFKTFPNQGEDPPXXXXXXXXXXXIDKTEFPNKDSDVINGKIKYLILSVFNATRNGYVFNGNILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI 1999
            MIQQRDSINCATNTQLKPAPMALFESIDEEQEYGSNSSLIESKLIRQENNSHNSLPDNEVILNHNRRPPPRKLTITQVPLTEYSRPLD ETNVILDSEQTQNRLKHFFDAKQREIRRQKCIRCCKQSIAFFFSQIGVMCIVVAYIIAGGFLFQNLEAKNEINISKSGESNINDSLKKLMEKIRSSEQETVDK+KSFCKRLIINQSSESNLRLTEFFNVNKKQLNNAIYTLQWNFQDMRTFIQEKITNIQSNLNLTKSSKFVSNNSALVIKDNLIEISNRLWDVGEEIKKLEALQNTFKTFPNQGEDPPLLKTKVKLLKTIDKTEFPNKDSDVINGKIKYLILSVFNATRNGYVFNGNILWTFSGALLYSITIITTIGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKE TTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI
Sbjct:    1 MIQQRDSINCATNTQLKPAPMALFESIDEEQEYGSNSSLIESKLIRQENNSHNSLPDNEVILNHNRRPPPRKLTITQVPLTEYSRPLDMETNVILDSEQTQNRLKHFFDAKQREIRRQKCIRCCKQSIAFFFSQIGVMCIVVAYIIAGGFLFQNLEAKNEINISKSGESNINDSLKKLMEKIRSSEQETVDKYKSFCKRLIINQSSESNLRLTEFFNVNKKQLNNAIYTLQWNFQDMRTFIQEKITNIQSNLNLTKSSKFVSNNSALVIKDNLIEISNRLWDVGEEIKKLEALQNTFKTFPNQGEDPPLLKTKVKLLKTIDKTEFPNKDSDVINGKIKYLILSVFNATRNGYVFNGNILWTFSGALLYSITIITTIGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKEITTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI 614

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Match: SMESG000013544.1 (SMESG000013544.1)

HSP 1 Score: 211.075 bits (536), Expect = 1.693e-58
Identity = 161/532 (30.26%), Postives = 268/532 (50.38%), Query Frame = 2

Query:  506 RQKCIRCCKQSIAFFFSQIGVMCIVVAYIIAGGFLFQNLEAKNEINISKSGESNINDSLKKLMEKIRSSEQETVDKHKSFCKRLIINQSSESNLRLTEFFNVNKKQLNNAIYTLQWNFQDMRTFIQEKITNIQSNLNLTKSSKFVSNNS-----ALVIKDNLIEISNRLWDVGEEI----KKLEALQNTFKTFPNQGEDPPXXXXXXXXXXXIDKTEFPNKDSDVINGKIKYLILSVFNATRNGYVF-NGNI---------LWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYI-----------KSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSF-------RMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRI 1990
            ++ CI   K +++  FS IG+  ++V YI+ G  +FQ  E K+E+   ++  + +  +L K   +I S  ++           ++++  +E+ + L +F N    +    I  L   F +++  IQ   + I  +       +   NNS     +  I      ISN+L  V E +    KK++ L N F      G+D  +       L    K+ F     + +    + L  +VF+ T++G++  NG+I         LWTF G++LY IT+ITTIGYGHI PKT  GRF TI+YAI GIP+ML+CL ++G +MA++F+ +YR +C K +             S K+     +LLD  +++                 +N  S+   +N   PT + F       ++   + N N +    + S+ V+VP+ L +T+  +Y LVG+  F+  +GW   +S YF FITL+TIGFGD VP    +G +++ Q KSI C+FY++ GL++  M F L+++K K   ++  KRI
Sbjct:  182 KEHCILFSKLALSLLFSNIGLTLLIVTYILLGACMFQFFELKHELATFETNSNKVLRNLNKSKSRIESEHEQ-----------IVLDIKNETKINLMKFLNETFTENQIKIGNLTEIFHEIKIQIQSAQSEIDRSFKEEILCQSTVNNSCERNDSEAIGKTWKNISNKLQSVNENVEIILKKIDNLSN-FINMKYNGKD--INSLIGNNLSLRQKSSFI----ESLTKNFENLTETVFDVTKDGWIHENGHIGTEKGSGKTLWTFGGSILYCITVITTIGYGHITPKTIPGRFGTIIYAIFGIPIMLICLAHIGSLMANMFRLIYRVSCLKAFKKYKKSQKSKCQNSEKQSSTSNELLDKSDDE-----------------DNQISLTVVKNPHNPTGNYFGSTVQFRKILFHIPNPNRLLEAAKKSKSVEVPVSLVITVFIIYNLVGSVFFTICEGWKITDSFYFSFITLSTIGFGDFVP--VAIGNEAE-QYKSIMCSFYVLFGLSLCVMSFDLMEKKCKSTIKKTVKRI 675

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Match: SMESG000078172.1 (SMESG000078172.1)

HSP 1 Score: 186.808 bits (473), Expect = 8.198e-51
Identity = 158/550 (28.73%), Postives = 250/550 (45.45%), Query Frame = 2

Query:  419 DTETNVILDSEQTQNRLKH-FFDAKQREIR----RQKCIRCCKQSIAFFFSQIGVMCIVVAYIIAGGFLFQNLEAKNEINISKSGESNINDSLKKLMEKIRSSEQETVDKHKSFCKRLIINQSSESNLRLTEFFNVNKKQLNNAIYTLQW--NFQDMRTFIQ------EKITNIQSNLNLTKSSKFVSNNSALVIKDNLIEISNRLWDVGEEIKKLEALQNTFKTFPNQGEDPPXXXXXXXXXXXIDKTEFPNKDSDVINGKIKYLILSVFNATRNGYVFNG---------NILWTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILK--------------KENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVK 1960
            + ++N++L+SE  +N   +  +   +  I+    R     C ++     FS IG+   V+ Y++ G F+FQ LE  +EI   K+ + ++  +   + E+I    Q        F   L  +Q+S + L   EF    +  LN  ++  +   +FQ  +T  Q      +   N + N N    + F +     +I      + N L++  E+    E  Q  FKT                                +I  +I+     +FNA+ NG              N +W F GALLY++T+ITTIGYGHI P+T  GR  TI+YAI+GIPLM++CL N+G +MAD+ + +YR       I S ++                     NKP+ +N+ S++ S I K              K+N  +    +  +S  L   N +      S+  +VP  L   I   Y L+G+ +F YW+ W F E+ YF FITL+TIGFGDLVP       +  +Q KSI C+ Y++ GL++  MCF L+ +K K
Sbjct:   62 NCKSNILLESESFKNSFNNKTYITPEESIKFWKSRAHFKTCTQRFFEIVFSNIGLSLAVIVYVLLGAFIFQFLEEMSEITRYKTYKKDVVLAKLNITEQIMMIHQNFEFPKSKF--HLNHSQASSNELNYYEF----RIFLNKILFYSETFRDFQQNKTLFQILCNGTDNFKNNEENCNFNWLADFYN-----LILPRFENLYNVLYNTSEDFGNSEQNQIKFKT--------------------------------LIKVEIEKFSNVIFNASSNGLSHKSFHESNKEEENTMWNFGGALLYAVTVITTIGYGHITPQTPLGRITTILYAIMGIPLMIICLANIGTLMADILRLIYR-------IFSMRK--------------------NNKPKMVNVKSDSFSDIFKSLTITVIRKNKLETKDNNFQSIFQNCNVSFKLPTPNSILKAARQSKSTEVPATLVFFIFIFYNLIGSTIFMYWEDWNFLEAVYFSFITLSTIGFGDLVPIK---STRQTEQYKSIICSIYVLFGLSLCIMCFDLLGQKAK 538

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Match: SMESG000016405.1 (SMESG000016405.1)

HSP 1 Score: 140.969 bits (354), Expect = 6.177e-36
Identity = 86/256 (33.59%), Postives = 139/256 (54.30%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI 1999
            W  + ++ +  TIITTIGYG+IVP T  GR + I+YA IGIPLMLL L+N G+V+A  F+F+Y    C + ++K +         +    +  KRS  + K    N   EN  ++        P        L +    ++D  ++  E +++P+ + +  L +Y+ +GA +F  W+ W    + YF FIT++TIGFGDL P    +G  S    + I  A Y + GLA+ +MC  L++E++ E F  LG ++G++
Sbjct:  118 WNLANSIFFCATIITTIGYGNIVPSTVWGRIVCIIYAFIGIPLMLLFLSNFGEVLASAFRFVYTNLCCCRCFVKGKYTS------ISEFESMSKRSAIEIK----NFELENAENLNSNPVKATPPPKFIDEDLDI---VYVDDENDQDEIINIPLTVVIGFLIIYMFLGALIFQIWETWDLVAAVYFSFITVSTIGFGDLYPAKNTIG-SSVATLELIVGAVYCIIGLAILSMCLNLVKEEIVEKFSWLGNKLGIV 359

[Close]

BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Match: SMESG000024430.1 (SMESG000024430.1)

HSP 1 Score: 139.428 bits (350), Expect = 1.516e-35
Identity = 91/257 (35.41%), Postives = 136/257 (52.92%), Query Frame = 2

Query: 1235 WTFSGALLYSXXXXXXXGYGHIVPKTFSGRFLTIVYAIIGIPLMLLCLTNLGKVMADLFKFMY-RFTCFKVYIKSRKRKECKQKLLDSQNNQRKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMDSVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDG-WTFFESCYFVFITLTTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKVKEWFEELGKRIGLI 1999
            W    ++ + +TIITTIGYG+I P T  G+  +++Y+I GIPLMLL LTN+G++MA  F+F+Y    C + +I  R       +++DS  N +K +     P  IN  +     I   EN                              V +PI + L +L +YI+VGA +F  W+  W+  +  YF +ITL TIGFGD VPG  +  EK++  T+ I    Y + GLA+ +MC  LIQ+++   F  LG ++GLI
Sbjct:  126 WNIYNSIFFCVTIITTIGYGNITPLTDWGKINSMIYSIFGIPLMLLFLTNVGEIMATFFRFIYLNLCCCRCFISRRV------EIVDSTENDKKLNIEGQPPPKINEGNHPDYEIEDDENVF----------------------------VVIPITVVLIVLFIYIIVGACLFRIWEQEWSMVDGTYFSYITLATIGFGDFVPGK-DGFEKAETGTELIVGGMYCLLGLAILSMCLNLIQDEIASKFRWLGNKLGLI 347

HSP 2 Score: 55.8398 bits (133), Expect = 6.667e-8
Identity = 32/84 (38.10%), Postives = 49/84 (58.33%), Query Frame = 2

Query:  482 DAKQREIRRQKCIRCCKQSIAFFFSQIGVMCIVVAYIIAGGFLFQNLEAKNEINISKSG----ESNINDSLKKLMEKIRSSEQE 721
            D  ++E  +QK   C + S+   FS IG   +V+ YII GGFLF+ LE  NEI + K       + +N+S++++M  I +S QE
Sbjct:    2 DNNEKENNKQKWKTCLQTSMKVAFSHIGTFLMVITYIIMGGFLFKYLEENNEILVCKEKYNKYSTKLNESIQRIM-AISTSRQE 84

The following BLAST results are available for this feature:

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Yeast
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNK18	6.293e-24	28.72	potassium two pore domain channel subfamily K memb...	[more]
KCNK9	6.653e-13	27.35	potassium two pore domain channel subfamily K memb...	[more]
KCNK9	6.878e-13	27.35	potassium two pore domain channel subfamily K memb...	[more]
KCNK9	6.878e-13	27.35	potassium two pore domain channel subfamily K memb...	[more]
KCNK9	6.878e-13	27.35	potassium two pore domain channel subfamily K memb...	[more]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
twk-48	6.622e-43	38.28	TWiK family of potassium channels [Source:UniProt...	[more]
twk-28	9.300e-25	25.89	TWiK family of potassium channels [Source:UniProt...	[more]
twk-31	1.634e-23	31.11	TWiK family of potassium channels [Source:UniProt...	[more]
twk-31	1.946e-23	31.11	TWiK family of potassium channels [Source:UniProt...	[more]
twk-13	4.787e-23	25.93	TWiK family of potassium channels [Source:UniProt...	[more]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sand	3.550e-35	35.34	gene:FBgn0033257 transcript:FBtr0088780	[more]
CG34396	5.290e-29	33.21	gene:FBgn0085425 transcript:FBtr0112644	[more]
CG34396	3.057e-26	31.82	gene:FBgn0085425 transcript:FBtr0112645	[more]
CG42594	1.184e-24	28.24	gene:FBgn0260971 transcript:FBtr0345704	[more]
CG42594	1.184e-24	28.24	gene:FBgn0260971 transcript:FBtr0301749	[more]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnk18	9.809e-19	26.71	potassium channel, subfamily K, member 18 [Source:...	[more]
kcnk18	1.278e-18	26.71	potassium channel, subfamily K, member 18 [Source:...	[more]
kcnk18	1.436e-18	26.71	potassium channel, subfamily K, member 18 [Source:...	[more]
kcnk1a	1.668e-12	24.45	potassium channel, subfamily K, member 1a [Source:...	[more]
kcnk1a	1.668e-12	24.45	potassium channel, subfamily K, member 1a [Source:...	[more]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNK18	1.455e-19	28.98	potassium two pore domain channel subfamily K memb...	[more]
pole4	9.098e-11	47.30	polymerase (DNA-directed), epsilon 4, accessory su...	[more]
pole4	1.975e-10	47.30	polymerase (DNA-directed), epsilon 4, accessory su...	[more]
pole4	2.937e-10	47.30	polymerase (DNA-directed), epsilon 4, accessory su...	[more]
tbc1d1	1.743e-9	42.11	TBC1 domain family member 1 [Source:Xenbase;Acc:XB...	[more]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Kcnk18	1.220e-21	28.67	potassium channel, subfamily K, member 18 [Source:...	[more]
Kcnk9	1.744e-12	27.35	potassium channel, subfamily K, member 9 [Source:M...	[more]
Kcnk3	2.683e-10	44.74	potassium channel, subfamily K, member 3 [Source:M...	[more]
Kcnk4	3.403e-9	37.08	potassium channel, subfamily K, member 4 [Source:M...	[more]
Kcnk10	5.419e-9	37.08	potassium channel, subfamily K, member 10 [Source:...	[more]

BLAST of Potassium channel subfamily K member 18 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q7Z418\|KCNKI_HUMAN	3.022e-23	28.72	Potassium channel subfamily K member 18 OS=Homo sa...	[more]
sp\|Q6Q1P3\|KCNKI_RAT	1.247e-22	28.47	Potassium channel subfamily K member 18 OS=Rattus ...	[more]
sp\|Q6VV64\|KCNKI_MOUSE	8.535e-21	28.67	Potassium channel subfamily K member 18 OS=Mus mus...	[more]
sp\|Q18120\|TWK18_CAEEL	3.448e-20	28.80	TWiK family of potassium channels protein 18 OS=Ca...	[more]
sp\|P34410\|TWK7_CAEEL	2.025e-17	31.03	TWiK family of potassium channels protein 7 OS=Cae...	[more]

BLAST of Potassium channel subfamily K member 18 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
G4V9R5	1.435e-48	37.97	Twik family of potassium channels-related OS=Schis...	[more]
T1IJW1	3.093e-47	41.96	Uncharacterized protein OS=Strigamia maritima OX=1...	[more]
A0A210QTX8	1.046e-46	38.71	TWiK family of potassium channels protein 18 OS=Mi...	[more]
T1EJ43	2.210e-46	40.61	Uncharacterized protein OS=Helobdella robusta OX=6...	[more]
A0A4Z2DMW5	2.263e-46	38.91	Potassium channel subfamily K member 18 OS=Schisto...	[more]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000047723.1	1.171e-21	29.68	pep primary_assembly:Astyanax_mexicanus-2.0:9:1589...	[more]
kcnk9	2.512e-14	26.94	potassium two pore domain channel subfamily K memb...	[more]
kcnk15	3.670e-11	43.62	potassium channel subfamily K member 15-like [Sour...	[more]
kcnk2b	4.228e-9	37.08	potassium channel, subfamily K, member 2b [Source:...	[more]
KCNK16	1.406e-7	41.94	potassium channel subfamily K member 16 [Source:NC...	[more]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000003416.1	2.009e-24	31.25	pep scaffold:Pmarinus_7.0:GL476517:78247:80718:1 g...	[more]
kcnk7	3.688e-7	43.08	potassium channel, subfamily K, member 7 [Source:Z...	[more]
KCNK10	5.233e-7	28.10	potassium two pore domain channel subfamily K memb...	[more]
kcnk13a	8.538e-7	25.12	potassium channel, subfamily K, member 13a [Source...	[more]
KCNK16	2.391e-6	38.03	potassium two pore domain channel subfamily K memb...	[more]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
TOK1	2.717e-7	23.36	Outward-rectifier potassium channel of the plasma ...	[more]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO48564	4.878e-13	23.15	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35592	1.562e-12	25.76	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34988	3.410e-11	28.42	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38072	5.269e-11	26.70	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47668	6.053e-10	50.88	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Potassium channel subfamily K member 18 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnk18	4.083e-20	27.24	potassium two pore domain channel subfamily K memb...	[more]
kcnk15	2.194e-11	42.71	potassium channel subfamily K member 15 [Source:NC...	[more]
kcnk3a	2.269e-11	44.59	potassium two pore domain channel subfamily K memb...	[more]
ENSORLT00000013824.2	7.024e-11	40.45	potassium channel subfamily K member 2-like [Sourc...	[more]
kcnk9	4.811e-10	42.11	potassium two pore domain channel subfamily K memb...	[more]

BLAST of Potassium channel subfamily K member 18 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000031911.1	0.000e+0	99.51	SMESG000031911.1	[more]
SMESG000013544.1	1.693e-58	30.26	SMESG000013544.1	[more]
SMESG000078172.1	8.198e-51	28.73	SMESG000078172.1	[more]
SMESG000016405.1	6.177e-36	33.59	SMESG000016405.1	[more]
SMESG000024430.1	1.516e-35	35.41	SMESG000024430.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30023385 ID=SMED30023385|Name=Potassium channel subfamily K member 18|organism=Schmidtea mediterranea sexual|type=transcript|length=2200bp
TTTCAAGTACATGTGATTTTTATTTTACATGAAATCTAAAAGAAACAACC
AGATGATGATTGTGTTGAATCGGAGATTTTATGAAAACACATTCGGATTT
TAGAGAAATATTTTTTTGTTGATTGTCGTCACCCCTCCCCAGAAATAAAT
CTGAAAAATGATTCAACAAAGAGATTCAATAAATTGTGCAACTAATACTC
AACTGAAACCGGCTCCGATGGCTTTGTTTGAATCTATCGATGAAGAACAA
GAATACGGATCCAATTCGTCTTTGATCGAATCGAAATTGATACGACAAGA
AAACAATTCTCACAACTCTTTACCAGACAACGAAGTGATTCTTAATCACA
ATAGAAGGCCTCCCCCGAGAAAATTGACAATAACTCAGGTTCCGTTGACT
GAATACTCAAGACCTCTCGACACGGAAACCAATGTCATCCTTGACTCGGA
ACAAACTCAAAATCGGCTGAAACATTTTTTCGACGCAAAACAGAGAGAAA
TTAGGCGTCAAAAATGCATTCGTTGTTGTAAGCAATCTATCGCTTTCTTT
TTCTCACAAATCGGAGTCATGTGCATCGTTGTGGCATATATCATTGCCGG
GGGATTTCTATTCCAGAATCTCGAAGCAAAAAATGAAATCAACATCTCAA
AATCTGGAGAATCAAATATCAACGATTCCCTAAAAAAACTCATGGAAAAA
ATCAGATCATCCGAACAAGAAACCGTGGACAAACACAAATCGTTCTGTAA
ACGTCTCATCATCAATCAGAGTTCCGAATCCAATTTGCGACTGACTGAAT
TTTTCAACGTCAACAAAAAACAACTGAATAATGCAATTTACACGTTGCAA
TGGAATTTCCAAGACATGAGGACTTTTATTCAGGAAAAGATTACGAACAT
TCAATCGAATCTCAACTTGACTAAATCATCGAAATTCGTTTCCAATAACA
GTGCACTGGTTATCAAAGACAATTTGATTGAGATTTCCAATCGACTGTGG
GACGTTGGGGAAGAAATCAAAAAATTAGAAGCCCTTCAAAACACTTTCAA
AACTTTTCCCAATCAAGGAGAAGATCCTCCACTATTGAAAACCAAAGTCA
AACTGCTCAAAACCATTGATAAAACTGAGTTCCCTAATAAAGATTCAGAT
GTAATTAATGGAAAAATAAAGTATTTAATTCTATCAGTTTTCAATGCCAC
AAGGAACGGATATGTTTTCAATGGAAACATTTTGTGGACCTTTTCCGGAG
CCCTGCTATACTCTATTACGATCATCACAACAATCGGATATGGTCATATC
GTTCCAAAAACGTTTAGTGGTCGATTTCTGACAATAGTTTATGCAATAAT
TGGTATTCCATTAATGCTTCTATGCTTGACAAACCTTGGAAAGGTTATGG
CGGATTTATTTAAGTTTATGTATCGGTTTACATGTTTTAAAGTTTACATA
AAGTCTCGAAAACGAAAAGAATGTAAGCAGAAGCTTTTAGACTCTCAAAA
TAATCAAAGAAAGCGATCCGGCAACCAAAATAAACCTGAATTCATAAACA
TTTTATCCGAGAATCCTTCTTCAATACTTAAAAAAGAAAATACAACCAAG
CCGACGATGCACTCGTTTCGCATGTCTTTACCTTTGGGTAATGCCAATTT
TATGGATTCTGTTCATGAAATCAGTGAAGAAGTTGATGTTCCTATTTGGC
TTCCTTTGACGATATTAGGACTTTATATTCTTGTCGGAGCGGCTGTGTTC
TCTTATTGGGATGGTTGGACATTTTTTGAATCCTGTTATTTCGTCTTCAT
CACTCTGACTACGATTGGGTTTGGAGATTTAGTACCGGGAAATTTTGAGT
TGGGAGAGAAAAGTCAAGATCAAACGAAATCTATATTCTGTGCATTCTAT
CTTGTAACTGGTTTAGCAGTTTTTGCAATGTGTTTCACGTTGATTCAAGA
AAAAGTCAAAGAATGGTTTGAAGAACTTGGAAAACGAATCGGTTTGATTT
GAAGTGAATCTAATCGTATAAATAGTTTCCAAGACATCCGGTGACAGATT
GAACATTTTTTTGGAAGAATCTCTAATAGAATATTTTTCTTTCTGTGATT
TAATTAGATTATTATATTGTATTCTTAATTCAATTATTTTCATTCATTTT
TTCCCTGAACTTTTTATAATGATCTGTTGAAATGTTACGGTTTTAAAAAT

protein sequence of SMED30023385-orf-1

>SMED30023385-orf-1 ID=SMED30023385-orf-1|Name=SMED30023385-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=615bp
MIQQRDSINCATNTQLKPAPMALFESIDEEQEYGSNSSLIESKLIRQENN
SHNSLPDNEVILNHNRRPPPRKLTITQVPLTEYSRPLDTETNVILDSEQT
QNRLKHFFDAKQREIRRQKCIRCCKQSIAFFFSQIGVMCIVVAYIIAGGF
LFQNLEAKNEINISKSGESNINDSLKKLMEKIRSSEQETVDKHKSFCKRL
IINQSSESNLRLTEFFNVNKKQLNNAIYTLQWNFQDMRTFIQEKITNIQS
NLNLTKSSKFVSNNSALVIKDNLIEISNRLWDVGEEIKKLEALQNTFKTF
PNQGEDPPLLKTKVKLLKTIDKTEFPNKDSDVINGKIKYLILSVFNATRN
GYVFNGNILWTFSGALLYSITIITTIGYGHIVPKTFSGRFLTIVYAIIGI
PLMLLCLTNLGKVMADLFKFMYRFTCFKVYIKSRKRKECKQKLLDSQNNQ
RKRSGNQNKPEFINILSENPSSILKKENTTKPTMHSFRMSLPLGNANFMD
SVHEISEEVDVPIWLPLTILGLYILVGAAVFSYWDGWTFFESCYFVFITL
TTIGFGDLVPGNFELGEKSQDQTKSIFCAFYLVTGLAVFAMCFTLIQEKV
KEWFEELGKRIGLI*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **INTERPRO**
Term	Definition
IPR003280	2pore_dom_K_chnl
IPR013099	K_chnl_dom

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **molecular function**
Term	Definition
GO:0005267	potassium channel activity

Vocabulary: **biological process**
Term	Definition
GO:0071805	potassium ion transmembrane transport
GO:0006810	transport
GO:0006811	ion transport

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 168..188
None	No IPR available	GENE3D	G3DSA:1.10.287.70		coord: 123..261 e-value: 9.7E-7 score: 30.2
None	No IPR available	PANTHER	PTHR11003	POTASSIUM CHANNEL, SUBFAMILY K	coord: 119..606
None	No IPR available	SUPERFAMILY	SSF81324	Voltage-gated potassium channels	coord: 511..609
None	No IPR available	SUPERFAMILY	SSF81324	Voltage-gated potassium channels	coord: 113..426
None	No IPR available	TMHMM	TMhelix		coord: 391..413
None	No IPR available	TMHMM	TMhelix		coord: 359..381
None	No IPR available	TMHMM	TMhelix		coord: 512..534
None	No IPR available	TMHMM	TMhelix		coord: 130..152
None	No IPR available	TMHMM	TMhelix		coord: 544..563
None	No IPR available	TMHMM	TMhelix		coord: 575..597
IPR003280	Two pore domain potassium channel	PRINTS	PR01333	2POREKCHANEL	coord: 371..399 score: 52.94 coord: 551..560 score: 77.71
IPR013099	Potassium channel domain	PFAM	PF07885	Ion_trans_2	coord: 519..600 e-value: 8.1E-19 score: 67.4 coord: 352..415 e-value: 4.2E-17 score: 61.9