Piezo-type mechanosensitive ion channel component

Overview
NamePiezo-type mechanosensitive ion channel component
Smed IDSMED30023379
Length (bp)8264
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Piezo-type mechanosensitive ion channel component (SMED30023379) t-SNE clustered cells

Violin plots show distribution of expression levels for Piezo-type mechanosensitive ion channel component (SMED30023379) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Piezo-type mechanosensitive ion channel component (SMED30023379) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Piezo-type mechanosensitive ion channel component (SMED30023379) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023379

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 22

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30023379h1SMcG0009875 PL08005A2E08smed_ncbi_20240424PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30023379h1SMcG0010500 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30023379h1SMcG0010500 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30023379h1SMcG0010500 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023379h1SMcG0010500 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023379h1SMcG0009875 Contig4157GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30023379h1SMcG0009875 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30023379h1SMcG0009875 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30023379h1SMcG0009875 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023379h1SMcG0009875 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30023379h1SMcG0009875 dd_Smed_v4_7182_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30023379h1SMcG0009875 dd_Smed_v4_7182_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30023379h1SMcG0009875 dd_Smed_v4_7182_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30023379h1SMcG0009875 dd_Smed_v4_7182_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30023379h1SMcG0009875 dd_Smed_v4_7182_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30023379h1SMcG0009875 dd_Smed_v4_7182_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023379h1SMcG0009875 dd_Smed_v4_7182_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023379h1SMcG0018728 Contig4157GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30023379h1SMcG0020490 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30023379h1SMcG0020490 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30023379h1SMcG0020490 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023379h1SMcG0020490 dd_Smed_v4_1447_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Human
Match: PIEZO1 (piezo type mechanosensitive ion channel component 1 [Source:HGNC Symbol;Acc:HGNC:28993])

HSP 1 Score: 461.84 bits (1187), Expect = 3.752e-130
Identity = 377/1422 (26.51%), Postives = 643/1422 (45.22%), Query Frame = 2 
Query:  308 FSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVN-TSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYK----EDIKMSSLKQ-SNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRF-LYG--------------------------------------DSREVG-----PFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCS--------LYTTNFNKSM---DQIDNAKWIGLEK----VNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKP-ETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQ-RKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-----LTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGG---GRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNE 4345
             +L I L  +P + + L   +C+ +  ++S  IG+T L        +RLV PD   L+ S V L    +    + Q P H ++  +D  +   S      ++    P+R   RL         +L   +G +L+                                              V +   AGI  PS L+SVYL  FL +CT+WAC   + T  F+ + + +  + A H+  LY  Q+   Q  LP     +R+LGL   V  T+C +   +   T   W  Y SP +++ + Y  AT + R     R S  R  + K     +++++ L Q   E + +  ++P                           P+   D+    ++T    + S +R    P  A               P E   L S+ +  +  S+V   IAMM WS+TY SW++F+LLL AC +W +    +  +  SP I+ Y   L  ++Y++  +L   PE   T     V L ++G      P   L  M+ + + FWL LR F+ + LL  ++    L +      + AD+E         + + +   + G+  KYWI VC    + VS    +VV++IVYM L +  L  F   YS WRK +  FWW V+ Y+++VL+ +YT+QF  FP  W+N TG ++E L D+GL+ +  S+LF  +L P  FL+  I+Q+ YFH+PF++L+ M    L G                                      DSR+ G     P +    +   ++    V+  + ++ + F  ++ +++ F         R  E H  K+V    V   + E +  N++L++L     P+ +   +    S  W  + ++ KM+YQLK VN   +S+NC+        L  T  ++S+     +D A W G+ K    +   Q+H+      +++  ++  + Y +++ Y+  +   P     +F   T Q +D  L+   K+ INF FYK GLE+ F++ V V   R++    ++   L+  L  + R+  +++W  Y LFL + L  +Y +C+G+PP LC  YP        +   L +WL+LP +   P++  +++DF   +  + Q++VF  E +       G    R  P+     P     +F+  + SY+D LK A+F + +WL L +VF TG   I++F LGY++  F  L  G  ++ R     +  W+ +I YN  VI+SK  L L+ C +++ M +  FCW+I LF + C     +D   + ++R         ++G+ WD  CF F++LQR++F++  + HV  DL      ASRG  L N   + SI   +  EE  L ++K ++++I  +Q +H +  ++ 
Sbjct:   75 LALQICLHIVPRL-DQLLGPSCS-RWETLSRHIGVTRLDLKDIPNAIRLVAPDLGILVVSSVCLGICGRLARNTRQSP-HPRELDDDERDVDASPTAGLQEAATLAPTR-RSRLAARFRVTAHWLLVAAGRVLA----------------------------------------------VTLLALAGIAHPSALSSVYLLLFLALCTWWACHFPISTRGFSRLCVAVGCFGAGHLICLYCYQMPLAQALLPPAGIWARVLGLKDFVGPTNCSSPHALVLNTGLDWPVYASPGVLLLLCY--ATASLRKLRAYRPSGQRKEAAKGYEARELELAELDQWPQERESDQHVVPTA-------------------------PDTEADNCIVHELTG---QSSVLRRPVRPKRA--------------EPREASPLHSLGHLIMDQSYVCALIAMMVWSITYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGMTLCCLRYVWAMDLR--PELPTTLG--PVSLRQLGLEHTRYPCLDLGAMLLYTLTFWLLLRQFVKEKLLKWAESPAALTEV-----TVADTEP---TRTQTLLQSLGELVKGVYAKYWIYVCAGMFIVVSFAGRLVVYKIVYMFLFLLCLTLFQVYYSLWRKLLKAFWWLVVAYTMLVLIAVYTFQFQDFPAYWRNLTGFTDEQLGDLGLEQFSVSELFSSILVPGFFLLACILQLHYFHRPFMQLTDMEHVSLPGTRLPRWAHRQDAVSGTPLLREEQQEHQQQQQEEEEEEEDSRDEGLGVATPHQAT-QVPEGAAKWGLVAERLLELAAGFSDVLSRVQVFLR-------RLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCVIIVCKMLYQLKVVNPQEYSSNCTEPFPNSTNLLPTEISQSLLYRGPVDPANWFGVRKGFPNLGYIQNHL-----QVLLLLVFEAIVYRRQEHYRRQHQLAPLPAQAVFASGTRQQLDQDLLGCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFLVTLHGCWLVAILTRRHRQAIARLWPNYCLFLALFLLYQYLLCLGMPPALCIDYPWRWSRAVPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGVNTDRLEPLRGEPNPV---PNFIHCR-SYLDMLKVAVFRYLFWLVLVVVFVTGATRISIFGLGYLLACFYLLLFGTALLQRDTRARLVLWDCLILYNVTVIISKNMLSLLACVFVEQMQTG-FCWVIQLFSLVCTVKGYYDPKEM-MDRDQDCLLPVEEAGIIWDSVCFFFLLLQRRVFLSHYYLHVRADLQATALLASRGFALYNAANLKSIDFHRRIEEKSLAQLKRQMERIRAKQEKHRQGRVDR 1371

HSP 2 Score: 396.356 bits (1017), Expect = 5.394e-110
Identity = 225/594 (37.88%), Postives = 347/594 (58.42%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKL-RSTESLKINMQAICERRSSDSKTTEKM-VRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQT-YLNLTLSMKKENEA------RWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            +RRF+  + + K+    DVY  MFL + + F+IIIFG+ +FG  + + D     +  +++P  F+ M++ QF  +++DRAL+LRK V GK  FQ+  VL IH W+FF LP +T++ FN  +  QL YFVKCIYFALSAYQ++ GYP RILGNFLT+ +N++NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  WM VED++  IF++KC R +E +YP  +G  ++   KY +GGL++ F     W PL   S + +   V N PI+ T ++ +GGY PLF   +++ ++       ++++   +        ++  +   D+    I+GSS  +W I+PPS  ++K +L   T  + +      +R  +   T E    +H      +   ++ L   +E      VV I  +FP+++ A     +     L+ + +  YL + + +++E  A       WW I E+    T C          + L + IFS++VS    G L + YGI+G+Y + + V  + +R F+S+IS+ I  EELP VDRIL L  +I+LVRE +   LEE+L AKLIFLYRS ETMIKWTR  +
Sbjct: 1942 LRRFFHDILHTKYRAATDVYALMFLADVVDFIIIIFGFWAFGKHSAATDITSS-LSDDQVPEAFLVMLLIQFSTMVVDRALYLRKTVLGKLAFQVALVLAIHLWMFFILPAVTERMFNQNVVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSSWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLVRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIIPFTAQAYEELSRQFDPQPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKRELYNGTADITLRFTWNFQRDLAKGGTVEYANEKHMLALAPNSTARRQLASLLEGTSDQSVV-IPNLFPKYIRAPNGPEANPVKQLQPNEEADYLGVRIQLRREQGAGATGFLEWWVI-ELQECRTDC----------NLLPMVIFSDKVSPPSLGFL-AGYGIMGLYVSIVLVIGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTREKE 2521

HSP 3 Score: 115.931 bits (289), Expect = 1.140e-24
Identity = 62/126 (49.21%), Postives = 85/126 (67.46%), Query Frame = 2 
Query: 5687 YSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRV---DPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTE 6055
            +SE +CYF++ILNHM++ +  SL  P++VFLWAMLS+PRPSK FW+  I +TEI +V+KY+FQF F  +N     R     P + P I+G+EK+  Y   DL+QL+ +F HR  L   GLW DH E
Sbjct: 1686 HSELLCYFIIILNHMVTASAGSLVLPVLVFLWAMLSIPRPSKRFWMTAIVFTEIAVVVKYLFQFGFFPWNSHVVLRRYENKPYFPPRILGLEKTDGYIKYDLVQLMALFFHRSQLLCYGLW-DHEE 1810
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Human
Match: PIEZO2 (piezo type mechanosensitive ion channel component 2 [Source:HGNC Symbol;Acc:HGNC:26270])

HSP 1 Score: 445.277 bits (1144), Expect = 6.837e-125
Identity = 226/588 (38.44%), Postives = 362/588 (61.56%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEAN---QSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARW---WEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            +++F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+  +  QL YFVKC+YF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++   KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   ++++ LK + + +F+K  + +   +    +L ++E  D+T   ++G+S+ +WTI+PPS +K+  +L    S    + +   +R+       ++     +  L    +KN+ K I  N    S   V I+ I+P ++ A   + S+    L   N  ++++T+ + ++N  ++   W +  +     Y  N +        L + +F+++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR
Sbjct: 2196 IKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENN-FMDITIILSRDNTTKYNSEWWVLNLTGNRIYNPNSQ-------ALELVVFNDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTR 2773

HSP 2 Score: 252.292 bits (643), Expect = 4.362e-66
Identity = 179/586 (30.55%), Postives = 300/586 (51.19%), Query Frame = 2 
Query: 2642 IIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN--------FNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS--SVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGK 4330
            ++  K  ++F  +   +W   E H  KIV   I+   + E +  N V +I      P+ KL  +  +    W  + ++ KM+YQL+T+   N+S NCSL   N         NKS+     ID  +W+GL K +    ++     +L + A    +  HQ  +    N T P +  IF + T   +DD LIN  K+ IN+ FYK GLE  F+++V V   R+D Y++++   L+ +    +RK  ++IW  Y  FL  ++  +Y IC+G+PP  C+ YP      S  +N+ +WL+ P +   P+   ++ DF   +  +LQ ++F  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  IF + +W  L I+F TG   I++FC+GY++  F +L  G +++L+   +++  W+ +I YN FVI  K  L +  C Y+  ++    CW+I  F + C         M A N     PC+  S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E+  +D++K ++D+I  RQ ++ K
Sbjct:  943 VLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIPFNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIHCR-SYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNS-CWLIQAFSLACTVK---GYQMPAAN----SPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKK 1518

HSP 3 Score: 248.054 bits (632), Expect = 1.042e-64
Identity = 202/780 (25.90%), Postives = 343/780 (43.97%), Query Frame = 2 
Query:  398 HQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNH-NNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEY------QTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPL-----------------------------LLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVD---------------------------------NMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN 2518
             QIG  +LKG      +R+ +PD    I S+ + +  R    K    P+ D+ +Q +    N    +G   DS             E    E  F   +      E + +    R++    + L + +G                +     VVVT   G +G++ PS+ +SVY F FLG+CT+W+         F+ + + L +++A H+  LYL Q +F Q  +P N++ +RL G+  ++ T C +  ++       W  + +P +++ +YY  AT  R W ++     P V+           + + E D  L   P +    +  SL  ++     E       Q  ++P+  L     G+  +       +    GP  A    D   +P     P++                                ++S+    ++ S++   IAMMAWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V Y  +L+I+QYI+ F   ELPE               GF +   P G LA  I F + FWL LR  +T+      K+  +L++ K     N + +    ++                                    I K + + +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WRK +  FW  V++Y+++VL+ IYTYQF  FP LW+N TGL +E L+D+GLK +  ++LF  +  P  FL+V I+ + YFH  FL+L+ + 
Sbjct:  104 RQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQK----PVTDEAAQSNPEFENEELAEGEKIDS------------EEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFIG--------------NMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYARLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQE-----PLVQD----------EGTKEEDKALACSPIQITAGRRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKA----DLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSF---ELPEIKKVP----------GFLEKKEP-GELASKILFTITFWLLLRQHLTEQKALQEKE-ALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLK 819

HSP 4 Score: 126.331 bits (316), Expect = 8.533e-28
Identity = 76/160 (47.50%), Postives = 100/160 (62.50%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVD-PLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW--RDHTEFAQDLEIVDKEQD-GRNKIKSS 6118
            LL  ++ N  +  SE VCYF++ILNHM+S ++ +L  P+++FLWAMLSVPRPS+ FW+  I YTE+ IV+KY FQF F  +N+      D P   P IIG+EK + Y + DLIQLL +F HR  LK +GLW   D TE     E  D E   G  +  SS
Sbjct: 1934 LLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSS 2093
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Human
Match: PIEZO2 (piezo type mechanosensitive ion channel component 2 [Source:HGNC Symbol;Acc:HGNC:26270])

HSP 1 Score: 444.891 bits (1143), Expect = 8.165e-125
Identity = 226/588 (38.44%), Postives = 362/588 (61.56%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEAN---QSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARW---WEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            +++F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+  +  QL YFVKC+YF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++   KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   ++++ LK + + +F+K  + +   +    +L ++E  D+T   ++G+S+ +WTI+PPS +K+  +L    S    + +   +R+       ++     +  L    +KN+ K I  N    S   V I+ I+P ++ A   + S+    L   N  ++++T+ + ++N  ++   W +  +     Y  N +        L + +F+++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR
Sbjct: 2171 IKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENN-FMDITIILSRDNTTKYNSEWWVLNLTGNRIYNPNSQ-------ALELVVFNDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTR 2748

HSP 2 Score: 252.677 bits (644), Expect = 3.787e-66
Identity = 179/586 (30.55%), Postives = 300/586 (51.19%), Query Frame = 2 
Query: 2642 IIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN--------FNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS--SVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGK 4330
            ++  K  ++F  +   +W   E H  KIV   I+   + E +  N V +I      P+ KL  +  +    W  + ++ KM+YQL+T+   N+S NCSL   N         NKS+     ID  +W+GL K +    ++     +L + A    +  HQ  +    N T P +  IF + T   +DD LIN  K+ IN+ FYK GLE  F+++V V   R+D Y++++   L+ +    +RK  ++IW  Y  FL  ++  +Y IC+G+PP  C+ YP      S  +N+ +WL+ P +   P+   ++ DF   +  +LQ ++F  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  IF + +W  L I+F TG   I++FC+GY++  F +L  G +++L+   +++  W+ +I YN FVI  K  L +  C Y+  ++    CW+I  F + C         M A N     PC+  S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E+  +D++K ++D+I  RQ ++ K
Sbjct:  918 VLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIPFNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIHCR-SYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNS-CWLIQAFSLACTVK---GYQMPAAN----SPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKK 1493

HSP 3 Score: 248.054 bits (632), Expect = 8.676e-65
Identity = 202/780 (25.90%), Postives = 343/780 (43.97%), Query Frame = 2 
Query:  398 HQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNH-NNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEY------QTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPL-----------------------------LLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVD---------------------------------NMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN 2518
             QIG  +LKG      +R+ +PD    I S+ + +  R    K    P+ D+ +Q +    N    +G   DS             E    E  F   +      E + +    R++    + L + +G                +     VVVT   G +G++ PS+ +SVY F FLG+CT+W+         F+ + + L +++A H+  LYL Q +F Q  +P N++ +RL G+  ++ T C +  ++       W  + +P +++ +YY  AT  R W ++     P V+           + + E D  L   P +    +  SL  ++     E       Q  ++P+  L     G+  +       +    GP  A    D   +P     P++                                ++S+    ++ S++   IAMMAWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V Y  +L+I+QYI+ F   ELPE               GF +   P G LA  I F + FWL LR  +T+      K+  +L++ K     N + +    ++                                    I K + + +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WRK +  FW  V++Y+++VL+ IYTYQF  FP LW+N TGL +E L+D+GLK +  ++LF  +  P  FL+V I+ + YFH  FL+L+ + 
Sbjct:  104 RQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQK----PVTDEAAQSNPEFENEELAEGEKIDS------------EEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFIG--------------NMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYARLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQE-----PLVQD----------EGTKEEDKALACSPIQITAGRRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKA----DLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSF---ELPEIKKVP----------GFLEKKEP-GELASKILFTITFWLLLRQHLTEQKALQEKE-ALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLK 819

HSP 4 Score: 126.331 bits (316), Expect = 8.095e-28
Identity = 76/165 (46.06%), Postives = 102/165 (61.82%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVD-PLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW--RDHTEFAQDLEIVDKE-------QDGRNKIKS 6115
            LL  ++ N  +  SE VCYF++ILNHM+S ++ +L  P+++FLWAMLSVPRPS+ FW+  I YTE+ IV+KY FQF F  +N+      D P   P IIG+EK + Y + DLIQLL +F HR  LK +GLW   D TE     E  D E       +D  + +KS
Sbjct: 1909 LLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKS 2073
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Human
Match: PIEZO2 (piezo type mechanosensitive ion channel component 2 [Source:HGNC Symbol;Acc:HGNC:26270])

HSP 1 Score: 444.891 bits (1143), Expect = 8.194e-125
Identity = 226/588 (38.44%), Postives = 362/588 (61.56%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEAN---QSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARW---WEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            +++F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+  +  QL YFVKC+YF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++   KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   ++++ LK + + +F+K  + +   +    +L ++E  D+T   ++G+S+ +WTI+PPS +K+  +L    S    + +   +R+       ++     +  L    +KN+ K I  N    S   V I+ I+P ++ A   + S+    L   N  ++++T+ + ++N  ++   W +  +     Y  N +        L + +F+++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR
Sbjct: 2122 IKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENN-FMDITIILSRDNTTKYNSEWWVLNLTGNRIYNPNSQ-------ALELVVFNDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTR 2699

HSP 2 Score: 249.21 bits (635), Expect = 3.567e-65
Identity = 179/588 (30.44%), Postives = 299/588 (50.85%), Query Frame = 2 
Query: 2642 IIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENAC--NIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN--------FNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS--SVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGK 4330
            ++  K  ++F  +   +W   E H  KIV   I+   + E      N V +I      P+ KL  +  +    W  + ++ KM+YQL+T+   N+S NCSL   N         NKS+     ID  +W+GL K +    ++     +L + A    +  HQ  +    N T P +  IF + T   +DD LIN  K+ IN+ FYK GLE  F+++V V   R+D Y++++   L+ +    +RK  ++IW  Y  FL  ++  +Y IC+G+PP  C+ YP      S  +N+ +WL+ P +   P+   ++ DF   +  +LQ ++F  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  IF + +W  L I+F TG   I++FC+GY++  F +L  G +++L+   +++  W+ +I YN FVI  K  L +  C Y+  ++    CW+I  F + C         M A N     PC+  S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E+  +D++K ++D+I  RQ ++ K
Sbjct:  867 VLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKEARVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIPFNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIHCR-SYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNS-CWLIQAFSLACTVK---GYQMPAAN----SPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKK 1444

HSP 3 Score: 248.054 bits (632), Expect = 9.235e-65
Identity = 202/780 (25.90%), Postives = 343/780 (43.97%), Query Frame = 2 
Query:  398 HQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNH-NNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEY------QTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPL-----------------------------LLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVD---------------------------------NMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN 2518
             QIG  +LKG      +R+ +PD    I S+ + +  R    K    P+ D+ +Q +    N    +G   DS             E    E  F   +      E + +    R++    + L + +G                +     VVVT   G +G++ PS+ +SVY F FLG+CT+W+         F+ + + L +++A H+  LYL Q +F Q  +P N++ +RL G+  ++ T C +  ++       W  + +P +++ +YY  AT  R W ++     P V+           + + E D  L   P +    +  SL  ++     E       Q  ++P+  L     G+  +       +    GP  A    D   +P     P++                                ++S+    ++ S++   IAMMAWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V Y  +L+I+QYI+ F   ELPE               GF +   P G LA  I F + FWL LR  +T+      K+  +L++ K     N + +    ++                                    I K + + +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WRK +  FW  V++Y+++VL+ IYTYQF  FP LW+N TGL +E L+D+GLK +  ++LF  +  P  FL+V I+ + YFH  FL+L+ + 
Sbjct:   53 RQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQK----PVTDEAAQSNPEFENEELAEGEKIDS------------EEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFIG--------------NMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYARLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQE-----PLVQD----------EGTKEEDKALACSPIQITAGRRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKA----DLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSF---ELPEIKKVP----------GFLEKKEP-GELASKILFTITFWLLLRQHLTEQKALQEKE-ALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLK 768

HSP 4 Score: 126.331 bits (316), Expect = 8.332e-28
Identity = 76/165 (46.06%), Postives = 102/165 (61.82%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVD-PLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW--RDHTEFAQDLEIVDKE-------QDGRNKIKS 6115
            LL  ++ N  +  SE VCYF++ILNHM+S ++ +L  P+++FLWAMLSVPRPS+ FW+  I YTE+ IV+KY FQF F  +N+      D P   P IIG+EK + Y + DLIQLL +F HR  LK +GLW   D TE     E  D E       +D  + +KS
Sbjct: 1860 LLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKS 2024
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Human
Match: PIEZO2 (piezo type mechanosensitive ion channel component 2 [Source:HGNC Symbol;Acc:HGNC:26270])

HSP 1 Score: 254.603 bits (649), Expect = 1.017e-66
Identity = 109/216 (50.46%), Postives = 162/216 (75.00%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSE 6820
            +++F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+  +  QL YFVKC+YF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE
Sbjct: 2171 IKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESE 2385

HSP 2 Score: 252.677 bits (644), Expect = 4.047e-66
Identity = 179/586 (30.55%), Postives = 300/586 (51.19%), Query Frame = 2 
Query: 2642 IIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN--------FNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS--SVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGK 4330
            ++  K  ++F  +   +W   E H  KIV   I+   + E +  N V +I      P+ KL  +  +    W  + ++ KM+YQL+T+   N+S NCSL   N         NKS+     ID  +W+GL K +    ++     +L + A    +  HQ  +    N T P +  IF + T   +DD LIN  K+ IN+ FYK GLE  F+++V V   R+D Y++++   L+ +    +RK  ++IW  Y  FL  ++  +Y IC+G+PP  C+ YP      S  +N+ +WL+ P +   P+   ++ DF   +  +LQ ++F  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  IF + +W  L I+F TG   I++FC+GY++  F +L  G +++L+   +++  W+ +I YN FVI  K  L +  C Y+  ++    CW+I  F + C         M A N     PC+  S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E+  +D++K ++D+I  RQ ++ K
Sbjct:  918 VLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIPFNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIHCR-SYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNS-CWLIQAFSLACTVK---GYQMPAAN----SPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKK 1493

HSP 3 Score: 247.669 bits (631), Expect = 1.079e-64
Identity = 202/780 (25.90%), Postives = 343/780 (43.97%), Query Frame = 2 
Query:  398 HQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNH-NNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEY------QTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPL-----------------------------LLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVD---------------------------------NMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN 2518
             QIG  +LKG      +R+ +PD    I S+ + +  R    K    P+ D+ +Q +    N    +G   DS             E    E  F   +      E + +    R++    + L + +G                +     VVVT   G +G++ PS+ +SVY F FLG+CT+W+         F+ + + L +++A H+  LYL Q +F Q  +P N++ +RL G+  ++ T C +  ++       W  + +P +++ +YY  AT  R W ++     P V+           + + E D  L   P +    +  SL  ++     E       Q  ++P+  L     G+  +       +    GP  A    D   +P     P++                                ++S+    ++ S++   IAMMAWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V Y  +L+I+QYI+ F   ELPE               GF +   P G LA  I F + FWL LR  +T+      K+  +L++ K     N + +    ++                                    I K + + +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WRK +  FW  V++Y+++VL+ IYTYQF  FP LW+N TGL +E L+D+GLK +  ++LF  +  P  FL+V I+ + YFH  FL+L+ + 
Sbjct:  104 RQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQK----PVTDEAAQSNPEFENEELAEGEKIDS------------EEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFIG--------------NMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYARLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQE-----PLVQD----------EGTKEEDKALACSPIQITAGRRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKA----DLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSF---ELPEIKKVP----------GFLEKKEP-GELASKILFTITFWLLLRQHLTEQKALQEKE-ALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLK 819

HSP 4 Score: 155.221 bits (391), Expect = 1.287e-36
Identity = 97/308 (31.49%), Postives = 167/308 (54.22%), Query Frame = 2 
Query: 7010 PLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQ---SSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARW---WEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            P+F   ++++ LK + + +F+K  + +   +    +L ++E  D+T   ++G+S+ +WTI+PPS +K+  +L    S    + +   +R+       ++     +  L    +KN+ K I  N    S   V I+ I+P ++ A   + S+    L   N  ++++T+ + ++N  ++   W +  +     Y  N +        L + +F+++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR
Sbjct: 2387 PIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENN-FMDITIILSRDNTTKYNSEWWVLNLTGNRIYNPNSQ-------ALELVVFNDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTR 2685

HSP 5 Score: 126.331 bits (316), Expect = 7.335e-28
Identity = 76/165 (46.06%), Postives = 102/165 (61.82%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVD-PLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW--RDHTEFAQDLEIVDKE-------QDGRNKIKS 6115
            LL  ++ N  +  SE VCYF++ILNHM+S ++ +L  P+++FLWAMLSVPRPS+ FW+  I YTE+ IV+KY FQF F  +N+      D P   P IIG+EK + Y + DLIQLL +F HR  LK +GLW   D TE     E  D E       +D  + +KS
Sbjct: 1909 LLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKS 2073
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Celegans
Match: pezo-1 (Piezo-type mechanosensitive ion channel component [Source:UniProtKB/TrEMBL;Acc:A0A061AE33])

HSP 1 Score: 366.696 bits (940), Expect = 8.186e-106
Identity = 272/950 (28.63%), Postives = 443/950 (46.63%), Query Frame = 2 
Query: 5345 SKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXX--XXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHT-----------------------EFAQDLEIVDKEQD------GRNKIKSSYEESSPTSNKWSCNPIYKMR------RFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENN-----LKSLPKDTFDKMKECYKNFSPPTD------------YLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNT----KQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRT-----LSEATALLKDHNQTYLNLTLSMKKENEAR-WWEIQEIVAGETYCSNEK--IPKQSHSN--------------------LTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHR-VLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            SK +++   +   I +  D   V +N   +E+R +   L  EK+ +K      +SN      ++ + V       S   V S N  E ++       + +S    L  ++ N    +++ +CYF  I+  +++G L +LP PLM   W  LS PRPSK FW+ +ITYTE VIVIK++ QF F+ +N  T     ++DP+ +  + G+ +  ++A+ D++ L  +F HR  L+  GLW+D                         + AQ+ ++V  + D      G   +  S   +     +  C P    +      RF  ++ +PKF    D+Y  MF  + I FLI+ FGY +FG G   + N  D +K ++IPV  + M++   + IIIDRAL+LRK V GK I+Q+  +  +H W+F  LP++T++   S    Q LY +K  YF +SA+Q+++GYP   +GN LT  +   N+  FK +M +PFL+ELR  +DW WTDTS+ LF +  +E+ +  IF +KC R+ E  YP  RG  +    KY +G  ++    I  + PL L S +      + P + T  IS+ GY PL+   ++ +N     L  +  D    + +   +     D            YL  +   D+  +     S+  W I+  S   +  KL    S  +N +   E            ++H+ +      LD   +  +  A+  +   + + I    P F+    +       S    ++ D N   +N T  M+K +EAR W++   +   +    NEK  I    H                      L V  F +R   +    +F   G+I +Y + I V  R ++R  ++     +   ELP+ D +L +  +IYLVRE K F LE+ L AKLIFL+RS  T+I+WTR +K
Sbjct:   97 SKVESTAKFIQKMIASALDLCSVTLNKLCREHRYVGFVLSKEKQKLKSGHSESLSNTSRKLTDIRSAV----DLPSLQLVQSANDVEKMETAVSVDWQQKSSATRLLNAVVNCIGAHTDILCYFFAIMTQVMTGGLITLPLPLMSLFWGNLSNPRPSKFFWVTMITYTECVIVIKFVCQFAFMPYNSITWRTEHQMDPMSLDKLFGVSQRDSFALWDIVLLFSLFFHRYMLRKLGLWKDANLTDTFTLKEEPRSASGSDTGSPKKIAQEPKVVVTQSDTLEGTSGGEIVIPSDPNAVSNMEELDCEPPIPEKQSGPIGRFIHQLFHPKFRYIRDLYPIMFGIDVICFLIMTFGYSAFGEG--GSGNVLDDVKASRIPVTLVVMLVGMTLAIIIDRALYLRKSVVGKLIYQVLMIAFLHIWVFLVLPNMTRRSAISNHVAQALYVIKSCYFLVSAWQIRNGYPELCIGNLLTHSYGMTNMIAFKVFMNIPFLFELRTAIDWTWTDTSMPLFDFFNMENFYAHIFNIKCARQFEAAYPAPRGIPKGKLVKYMMGFPIIIGVVIFIFSPLLLWSLLNQIGTISMPEKVTLRISIEGYPPLYEMEAQGSNHDNAELGMIKPDQLASLNQALTDSYTTRDTNSILRSRMSVSYLKGYTYEDILIVRFRPESEIYWPISQDSRNAMIDKLSRNTS--VNFEVSLEFTRPYDPNENAALKHSKSWLVPISLDMTIRAKIQSALRGD-PGHPILIPQSIPAFIQVPNQGELTLPTSIGNTIINDGNPR-IN-TTGMEKSDEARAWFDSLTLNLEQGKSQNEKMWIATSEHPGDQNAKLWIKTANTTYSGRPYLQVVGFIDRAFPSFLAKVFKG-GVIAVYLSVILVVGRGLVRGIFTTSPSTVMFTELPNADHLLKICLDIYLVREAKDFMLEQDLFAKLIFLFRSPATLIEWTRMSK 1034
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Celegans
Match: pezo-1 (Piezo-type mechanosensitive ion channel component [Source:UniProtKB/TrEMBL;Acc:A0A061AE33])

HSP 1 Score: 364.385 bits (934), Expect = 1.391e-101
Identity = 273/950 (28.74%), Postives = 442/950 (46.53%), Query Frame = 2 
Query: 5345 SKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXX--XXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHT-----------------------EFAQDLEIVDKEQD------GRNKIKSSYEESSPTSNKWSCNPIYKMR------RFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENN-----LKSLPKDTFDKMKECYKNFSPPTD------------YLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNT----KQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRT-----LSEATALLKDHNQTYLNLTLSMKKENEAR-WWEIQEIVAGETYCSNEK--IPKQSHSN--------------------LTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVL-RAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            SK +++   +   I +  D   V +N   +E+R +   L  EK+ +K      +SN      ++ + V       S   V S N  E ++       + +S    L  ++ N    +++ +CYF  I+  +++G L +LP PLM   W  LS PRPSK FW+ +ITYTE VIVIK++ QF F+ +N  T     ++DP+ +  + G+ +  ++A+ D++ L  +F HR  L+  GLW+D                         + AQ+ ++V  + D      G   +  S   +     +  C P    +      RF  ++ +PKF    D+Y  MF  + I FLI+ FGY +FG G   + N  D +K ++IPV  + M++   + IIIDRAL+LRK V GK I+Q+  +  +H W+F  LP++T++   S    Q LY +K  YF +SA+Q+++GYP   +GN LT  +   N+  FK +M +PFL+ELR  +DW WTDTS+ LF +  +E+ +  IF +KC R+ E  YP  RG  +    KY +G  ++    I  + PL L S +      + P + T  IS+ GY PL+   ++ +N     L  +  D    + +   +     D            YL  +   D+  +     S+  W I+  S   +  KL    S  +N +   E            ++H+ +      LD   +  +  A+  +   + + I    P F+    +       S    ++ D N   +N T  M+K +EAR W++   +   +    NEK  I    H                      L V  F +R   +    +F   G+I +Y + I V  R L R  ++     +   ELP+ D +L +  +IYLVRE K F LE+ L AKLIFL+RS  T+I+WTR +K
Sbjct:  745 SKVESTAKFIQKMIASALDLCSVTLNKLCREHRYVGFVLSKEKQKLKSGHSESLSNTSRKLTDIRSAV----DLPSLQLVQSANDVEKMETAVSVDWQQKSSATRLLNAVVNCIGAHTDILCYFFAIMTQVMTGGLITLPLPLMSLFWGNLSNPRPSKFFWVTMITYTECVIVIKFVCQFAFMPYNSITWRTEHQMDPMSLDKLFGVSQRDSFALWDIVLLFSLFFHRYMLRKLGLWKDANLTDTFTLKEEPRSASGSDTGSPKKIAQEPKVVVTQSDTLEGTSGGEIVIPSDPNAVSNMEELDCEPPIPEKQSGPIGRFIHQLFHPKFRYIRDLYPIMFGIDVICFLIMTFGYSAFGEG--GSGNVLDDVKASRIPVTLVVMLVGMTLAIIIDRALYLRKSVVGKLIYQVLMIAFLHIWVFLVLPNMTRRSAISNHVAQALYVIKSCYFLVSAWQIRNGYPELCIGNLLTHSYGMTNMIAFKVFMNIPFLFELRTAIDWTWTDTSMPLFDFFNMENFYAHIFNIKCARQFEAAYPAPRGIPKGKLVKYMMGFPIIIGVVIFIFSPLLLWSLLNQIGTISMPEKVTLRISIEGYPPLYEMEAQGSNHDNAELGMIKPDQLASLNQALTDSYTTRDTNSILRSRMSVSYLKGYTYEDILIVRFRPESEIYWPISQDSRNAMIDKLSRNTS--VNFEVSLEFTRPYDPNENAALKHSKSWLVPISLDMTIRAKIQSALRGD-PGHPILIPQSIPAFIQVPNQGELTLPTSIGNTIINDGNPR-IN-TTGMEKSDEARAWFDSLTLNLEQGKSQNEKMWIATSEHPGDQNAKLWIKTANTTYSGRPYLQVVGFIDRAFPSFLAKVFKG-GVIAVYLSVILVVGRGLVRGIFTTSPSTVMFTELPNADHLLKICLDIYLVREAKDFMLEQDLFAKLIFLFRSPATLIEWTRMSK 1682

HSP 2 Score: 201.83 bits (512), Expect = 2.291e-51
Identity = 178/669 (26.61%), Postives = 299/669 (44.69%), Query Frame = 2 
Query: 2477 RYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCS---LTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLV---VCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLT--------SLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNI-----MLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMI-----SKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS-SVKSG-LHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECV---LXXXXXXXXXXXQRQAQHGKPELN----EHYLVVRSGDKYLF 4384
            ++FH P+ + +S  R             D    +T +++ ++ S      ++A   +++KL +        +WRFFE H +KIV   I     N  NA  I L+IL+ +          +   S F C+   L  L KMIYQL  V +    +         N S   I   +W GL+K     + I+    V+V     A   +V Y QR +       +     +FP+      D SL N  +F I++ FYK GLE++ I   I    R+D  + +    L++F   +R    +IW+ Y++++ +L P+++   VGLPP  C +YP +          + NL   L L  Y     +  ++ DFF  +  + Q  VF  E     + Y  G    ++  E P+    DF+ TK SYVDY K  +F++ +W++L      G+   +LF LGY+I     LW G N+      LR   + +  WN ++ Y  F I  K  LQ+ GC ++ W        K  C +  LF + C+N    + ++L         C+   K G + +DV    F++ Q +IF +  F H +++   +   A+RGA L N+ +   ++EQ  +++     + +    I +  Q+Q + G  E +     +    R+GD Y+F
Sbjct:    5 KFFHGPWSRATSPRR----------AENDPPTSTTEAAAVASTSGTQGRAHAAGDTLVKKLHKLANQTIELLWRFFEVHISKIVFVIIAIFIANNINALYIPLVILLSLAICLPSAADGIF--SLFMCAYLFLVALSKMIYQLDIVPEL---SQIDRGVGADNCSHGNISMPEWFGLKKEVEGTEPIYMLFGVIVSIIALAFQSIVIYRQRHYRASLGLPESMRAKVFPDFHHSHFDRSLKNAIQFLIDYGFYKFGLEITMIAIGIDIFNRMDALAAIQCFWLVLFALNKRVFVRRIWVFYVIYMAILYPLQFFSYVGLPPDSCIEYPWSYWIPSYSDDARFNLSYLLNLSIYGVNWPSAYLIGDFFVLLLASCQLAVFRREGEDNDSIYNDGNF--VIKPENPQY---DFIDTKKSYVDYFKSFVFHYGHWITLMSTLAAGIAGTSLFALGYIIFTLTMLWSGNNLYVMNSTLRSFEHTLKRWNALLGYTLFTITMKVCLQIFGCVFLSWFDQSGGWGKTLCIVRQLFSITCVNN---ECHVLKELEDFSKACAVETKEGNIGFDVIALSFLVFQIRIFHSWYFQHCMVEYRSEVILANRGAVLKNQLIEKEMKEQNEQQKAKFNDIRRRTEAIRERYQKQIERGAAERDFEPVTYGHAKRAGDYYMF 650
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Celegans
Match: pezo-1 (Piezo-type mechanosensitive ion channel component [Source:UniProtKB/TrEMBL;Acc:A0A061AE33])

HSP 1 Score: 364.77 bits (935), Expect = 1.541e-101
Identity = 273/950 (28.74%), Postives = 442/950 (46.53%), Query Frame = 2 
Query: 5345 SKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXX--XXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHT-----------------------EFAQDLEIVDKEQD------GRNKIKSSYEESSPTSNKWSCNPIYKMR------RFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENN-----LKSLPKDTFDKMKECYKNFSPPTD------------YLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNT----KQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRT-----LSEATALLKDHNQTYLNLTLSMKKENEAR-WWEIQEIVAGETYCSNEK--IPKQSHSN--------------------LTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVL-RAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            SK +++   +   I +  D   V +N   +E+R +   L  EK+ +K      +SN      ++ + V       S   V S N  E ++       + +S    L  ++ N    +++ +CYF  I+  +++G L +LP PLM   W  LS PRPSK FW+ +ITYTE VIVIK++ QF F+ +N  T     ++DP+ +  + G+ +  ++A+ D++ L  +F HR  L+  GLW+D                         + AQ+ ++V  + D      G   +  S   +     +  C P    +      RF  ++ +PKF    D+Y  MF  + I FLI+ FGY +FG G   + N  D +K ++IPV  + M++   + IIIDRAL+LRK V GK I+Q+  +  +H W+F  LP++T++   S    Q LY +K  YF +SA+Q+++GYP   +GN LT  +   N+  FK +M +PFL+ELR  +DW WTDTS+ LF +  +E+ +  IF +KC R+ E  YP  RG  +    KY +G  ++    I  + PL L S +      + P + T  IS+ GY PL+   ++ +N     L  +  D    + +   +     D            YL  +   D+  +     S+  W I+  S   +  KL    S  +N +   E            ++H+ +      LD   +  +  A+  +   + + I    P F+    +       S    ++ D N   +N T  M+K +EAR W++   +   +    NEK  I    H                      L V  F +R   +    +F   G+I +Y + I V  R L R  ++     +   ELP+ D +L +  +IYLVRE K F LE+ L AKLIFL+RS  T+I+WTR +K
Sbjct:  789 SKVESTAKFIQKMIASALDLCSVTLNKLCREHRYVGFVLSKEKQKLKSGHSESLSNTSRKLTDIRSAV----DLPSLQLVQSANDVEKMETAVSVDWQQKSSATRLLNAVVNCIGAHTDILCYFFAIMTQVMTGGLITLPLPLMSLFWGNLSNPRPSKFFWVTMITYTECVIVIKFVCQFAFMPYNSITWRTEHQMDPMSLDKLFGVSQRDSFALWDIVLLFSLFFHRYMLRKLGLWKDANLTDTFTLKEEPRSASGSDTGSPKKIAQEPKVVVTQSDTLEGTSGGEIVIPSDPNAVSNMEELDCEPPIPEKQSGPIGRFIHQLFHPKFRYIRDLYPIMFGIDVICFLIMTFGYSAFGEG--GSGNVLDDVKASRIPVTLVVMLVGMTLAIIIDRALYLRKSVVGKLIYQVLMIAFLHIWVFLVLPNMTRRSAISNHVAQALYVIKSCYFLVSAWQIRNGYPELCIGNLLTHSYGMTNMIAFKVFMNIPFLFELRTAIDWTWTDTSMPLFDFFNMENFYAHIFNIKCARQFEAAYPAPRGIPKGKLVKYMMGFPIIIGVVIFIFSPLLLWSLLNQIGTISMPEKVTLRISIEGYPPLYEMEAQGSNHDNAELGMIKPDQLASLNQALTDSYTTRDTNSILRSRMSVSYLKGYTYEDILIVRFRPESEIYWPISQDSRNAMIDKLSRNTS--VNFEVSLEFTRPYDPNENAALKHSKSWLVPISLDMTIRAKIQSALRGD-PGHPILIPQSIPAFIQVPNQGELTLPTSIGNTIINDGNPR-IN-TTGMEKSDEARAWFDSLTLNLEQGKSQNEKMWIATSEHPGDQNAKLWIKTANTTYSGRPYLQVVGFIDRAFPSFLAKVFKG-GVIAVYLSVILVVGRGLVRGIFTTSPSTVMFTELPNADHLLKICLDIYLVREAKDFMLEQDLFAKLIFLFRSPATLIEWTRMSK 1726

HSP 2 Score: 196.438 bits (498), Expect = 1.232e-49
Identity = 159/567 (28.04%), Postives = 258/567 (45.50%), Query Frame = 2 
Query: 2645 IIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCS---LTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLV---VCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLT--------SLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNI-----MLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMI-----SKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS-SVKSG-LHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEEC 4267
            +++KL +        +WRFFE H +KIV   I     N  NA  I L+IL+ +          +   S F C+   L  L KMIYQL  V +    +         N S   I   +W GL+K     + I+    V+V     A   +V Y QR +       +     +FP+      D SL N  +F I++ FYK GLE++ I   I    R+D  + +    L++F   +R    +IW+ Y++++ +L P+++   VGLPP  C +YP +          + NL   L L  Y     +  ++ DFF  +  + Q  VF  E     + Y  G    ++  E P+    DF+ TK SYVDY K  +F++ +W++L      G+   +LF LGY+I     LW G N+      LR   + +  WN ++ Y  F I  K  LQ+ GC ++ W        K  C +  LF + C+N    + ++L         C+   K G + +DV    F++ Q +IF +  F H +++   +   A+RGA L N+ +   ++EQ  +++ 
Sbjct:   69 LVKKLHKLANQTIELLWRFFEVHISKIVFVIIAIFIANNINALYIPLVILLSLAICLPSAADGIF--SLFMCAYLFLVALSKMIYQLDIVPEL---SQIDRGVGADNCSHGNISMPEWFGLKKEVEGTEPIYMLFGVIVSIIALAFQSIVIYRQRHYRASLGLPESMRAKVFPDFHHSHFDRSLKNAIQFLIDYGFYKFGLEITMIAIGIDIFNRMDALAAIQCFWLVLFALNKRVFVRRIWVFYVIYMAILYPLQFFSYVGLPPDSCIEYPWSYWIPSYSDDARFNLSYLLNLSIYGVNWPSAYLIGDFFVLLLASCQLAVFRREGEDNDSIYNDGNF--VIKPENPQY---DFIDTKKSYVDYFKSFVFHYGHWITLMSTLAAGIAGTSLFALGYIIFTLTMLWSGNNLYVMNSTLRSFEHTLKRWNALLGYTLFTITMKVCLQIFGCVFLSWFDQSGGWGKTLCIVRQLFSITCVNN---ECHVLKELEDFSKACAVETKEGNIGFDVIALSFLVFQIRIFHSWYFQHCMVEYRSEVILANRGAVLKNQLIEKEMKEQNEQQKA 622
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Celegans
Match: pezo-1 (Piezo-type mechanosensitive ion channel component [Source:UniProtKB/TrEMBL;Acc:A0A061AE33])

HSP 1 Score: 364.77 bits (935), Expect = 1.541e-101
Identity = 273/950 (28.74%), Postives = 442/950 (46.53%), Query Frame = 2 
Query: 5345 SKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXX--XXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHT-----------------------EFAQDLEIVDKEQD------GRNKIKSSYEESSPTSNKWSCNPIYKMR------RFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENN-----LKSLPKDTFDKMKECYKNFSPPTD------------YLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNT----KQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRT-----LSEATALLKDHNQTYLNLTLSMKKENEAR-WWEIQEIVAGETYCSNEK--IPKQSHSN--------------------LTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVL-RAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            SK +++   +   I +  D   V +N   +E+R +   L  EK+ +K      +SN      ++ + V       S   V S N  E ++       + +S    L  ++ N    +++ +CYF  I+  +++G L +LP PLM   W  LS PRPSK FW+ +ITYTE VIVIK++ QF F+ +N  T     ++DP+ +  + G+ +  ++A+ D++ L  +F HR  L+  GLW+D                         + AQ+ ++V  + D      G   +  S   +     +  C P    +      RF  ++ +PKF    D+Y  MF  + I FLI+ FGY +FG G   + N  D +K ++IPV  + M++   + IIIDRAL+LRK V GK I+Q+  +  +H W+F  LP++T++   S    Q LY +K  YF +SA+Q+++GYP   +GN LT  +   N+  FK +M +PFL+ELR  +DW WTDTS+ LF +  +E+ +  IF +KC R+ E  YP  RG  +    KY +G  ++    I  + PL L S +      + P + T  IS+ GY PL+   ++ +N     L  +  D    + +   +     D            YL  +   D+  +     S+  W I+  S   +  KL    S  +N +   E            ++H+ +      LD   +  +  A+  +   + + I    P F+    +       S    ++ D N   +N T  M+K +EAR W++   +   +    NEK  I    H                      L V  F +R   +    +F   G+I +Y + I V  R L R  ++     +   ELP+ D +L +  +IYLVRE K F LE+ L AKLIFL+RS  T+I+WTR +K
Sbjct:  789 SKVESTAKFIQKMIASALDLCSVTLNKLCREHRYVGFVLSKEKQKLKSGHSESLSNTSRKLTDIRSAV----DLPSLQLVQSANDVEKMETAVSVDWQQKSSATRLLNAVVNCIGAHTDILCYFFAIMTQVMTGGLITLPLPLMSLFWGNLSNPRPSKFFWVTMITYTECVIVIKFVCQFAFMPYNSITWRTEHQMDPMSLDKLFGVSQRDSFALWDIVLLFSLFFHRYMLRKLGLWKDANLTDTFTLKEEPRSASGSDTGSPKKIAQEPKVVVTQSDTLEGTSGGEIVIPSDPNAVSNMEELDCEPPIPEKQSGPIGRFIHQLFHPKFRYIRDLYPIMFGIDVICFLIMTFGYSAFGEG--GSGNVLDDVKASRIPVTLVVMLVGMTLAIIIDRALYLRKSVVGKLIYQVLMIAFLHIWVFLVLPNMTRRSAISNHVAQALYVIKSCYFLVSAWQIRNGYPELCIGNLLTHSYGMTNMIAFKVFMNIPFLFELRTAIDWTWTDTSMPLFDFFNMENFYAHIFNIKCARQFEAAYPAPRGIPKGKLVKYMMGFPIIIGVVIFIFSPLLLWSLLNQIGTISMPEKVTLRISIEGYPPLYEMEAQGSNHDNAELGMIKPDQLASLNQALTDSYTTRDTNSILRSRMSVSYLKGYTYEDILIVRFRPESEIYWPISQDSRNAMIDKLSRNTS--VNFEVSLEFTRPYDPNENAALKHSKSWLVPISLDMTIRAKIQSALRGD-PGHPILIPQSIPAFIQVPNQGELTLPTSIGNTIINDGNPR-IN-TTGMEKSDEARAWFDSLTLNLEQGKSQNEKMWIATSEHPGDQNAKLWIKTANTTYSGRPYLQVVGFIDRAFPSFLAKVFKG-GVIAVYLSVILVVGRGLVRGIFTTSPSTVMFTELPNADHLLKICLDIYLVREAKDFMLEQDLFAKLIFLFRSPATLIEWTRMSK 1726

HSP 2 Score: 196.438 bits (498), Expect = 1.232e-49
Identity = 159/567 (28.04%), Postives = 258/567 (45.50%), Query Frame = 2 
Query: 2645 IIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCS---LTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLV---VCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLT--------SLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNI-----MLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMI-----SKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS-SVKSG-LHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEEC 4267
            +++KL +        +WRFFE H +KIV   I     N  NA  I L+IL+ +          +   S F C+   L  L KMIYQL  V +    +         N S   I   +W GL+K     + I+    V+V     A   +V Y QR +       +     +FP+      D SL N  +F I++ FYK GLE++ I   I    R+D  + +    L++F   +R    +IW+ Y++++ +L P+++   VGLPP  C +YP +          + NL   L L  Y     +  ++ DFF  +  + Q  VF  E     + Y  G    ++  E P+    DF+ TK SYVDY K  +F++ +W++L      G+   +LF LGY+I     LW G N+      LR   + +  WN ++ Y  F I  K  LQ+ GC ++ W        K  C +  LF + C+N    + ++L         C+   K G + +DV    F++ Q +IF +  F H +++   +   A+RGA L N+ +   ++EQ  +++ 
Sbjct:   69 LVKKLHKLANQTIELLWRFFEVHISKIVFVIIAIFIANNINALYIPLVILLSLAICLPSAADGIF--SLFMCAYLFLVALSKMIYQLDIVPEL---SQIDRGVGADNCSHGNISMPEWFGLKKEVEGTEPIYMLFGVIVSIIALAFQSIVIYRQRHYRASLGLPESMRAKVFPDFHHSHFDRSLKNAIQFLIDYGFYKFGLEITMIAIGIDIFNRMDALAAIQCFWLVLFALNKRVFVRRIWVFYVIYMAILYPLQFFSYVGLPPDSCIEYPWSYWIPSYSDDARFNLSYLLNLSIYGVNWPSAYLIGDFFVLLLASCQLAVFRREGEDNDSIYNDGNF--VIKPENPQY---DFIDTKKSYVDYFKSFVFHYGHWITLMSTLAAGIAGTSLFALGYIIFTLTMLWSGNNLYVMNSTLRSFEHTLKRWNALLGYTLFTITMKVCLQIFGCVFLSWFDQSGGWGKTLCIVRQLFSITCVNN---ECHVLKELEDFSKACAVETKEGNIGFDVIALSFLVFQIRIFHSWYFQHCMVEYRSEVILANRGAVLKNQLIEKEMKEQNEQQKA 622
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Celegans
Match: pezo-1 (Piezo-type mechanosensitive ion channel component [Source:UniProtKB/TrEMBL;Acc:A0A061AE33])

HSP 1 Score: 363.999 bits (933), Expect = 1.866e-101
Identity = 273/950 (28.74%), Postives = 442/950 (46.53%), Query Frame = 2 
Query: 5345 SKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXX--XXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHT-----------------------EFAQDLEIVDKEQD------GRNKIKSSYEESSPTSNKWSCNPIYKMR------RFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENN-----LKSLPKDTFDKMKECYKNFSPPTD------------YLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNT----KQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRT-----LSEATALLKDHNQTYLNLTLSMKKENEAR-WWEIQEIVAGETYCSNEK--IPKQSHSN--------------------LTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVL-RAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            SK +++   +   I +  D   V +N   +E+R +   L  EK+ +K      +SN      ++ + V       S   V S N  E ++       + +S    L  ++ N    +++ +CYF  I+  +++G L +LP PLM   W  LS PRPSK FW+ +ITYTE VIVIK++ QF F+ +N  T     ++DP+ +  + G+ +  ++A+ D++ L  +F HR  L+  GLW+D                         + AQ+ ++V  + D      G   +  S   +     +  C P    +      RF  ++ +PKF    D+Y  MF  + I FLI+ FGY +FG G   + N  D +K ++IPV  + M++   + IIIDRAL+LRK V GK I+Q+  +  +H W+F  LP++T++   S    Q LY +K  YF +SA+Q+++GYP   +GN LT  +   N+  FK +M +PFL+ELR  +DW WTDTS+ LF +  +E+ +  IF +KC R+ E  YP  RG  +    KY +G  ++    I  + PL L S +      + P + T  IS+ GY PL+   ++ +N     L  +  D    + +   +     D            YL  +   D+  +     S+  W I+  S   +  KL    S  +N +   E            ++H+ +      LD   +  +  A+  +   + + I    P F+    +       S    ++ D N   +N T  M+K +EAR W++   +   +    NEK  I    H                      L V  F +R   +    +F   G+I +Y + I V  R L R  ++     +   ELP+ D +L +  +IYLVRE K F LE+ L AKLIFL+RS  T+I+WTR +K
Sbjct:  763 SKVESTAKFIQKMIASALDLCSVTLNKLCREHRYVGFVLSKEKQKLKSGHSESLSNTSRKLTDIRSAV----DLPSLQLVQSANDVEKMETAVSVDWQQKSSATRLLNAVVNCIGAHTDILCYFFAIMTQVMTGGLITLPLPLMSLFWGNLSNPRPSKFFWVTMITYTECVIVIKFVCQFAFMPYNSITWRTEHQMDPMSLDKLFGVSQRDSFALWDIVLLFSLFFHRYMLRKLGLWKDANLTDTFTLKEEPRSASGSDTGSPKKIAQEPKVVVTQSDTLEGTSGGEIVIPSDPNAVSNMEELDCEPPIPEKQSGPIGRFIHQLFHPKFRYIRDLYPIMFGIDVICFLIMTFGYSAFGEG--GSGNVLDDVKASRIPVTLVVMLVGMTLAIIIDRALYLRKSVVGKLIYQVLMIAFLHIWVFLVLPNMTRRSAISNHVAQALYVIKSCYFLVSAWQIRNGYPELCIGNLLTHSYGMTNMIAFKVFMNIPFLFELRTAIDWTWTDTSMPLFDFFNMENFYAHIFNIKCARQFEAAYPAPRGIPKGKLVKYMMGFPIIIGVVIFIFSPLLLWSLLNQIGTISMPEKVTLRISIEGYPPLYEMEAQGSNHDNAELGMIKPDQLASLNQALTDSYTTRDTNSILRSRMSVSYLKGYTYEDILIVRFRPESEIYWPISQDSRNAMIDKLSRNTS--VNFEVSLEFTRPYDPNENAALKHSKSWLVPISLDMTIRAKIQSALRGD-PGHPILIPQSIPAFIQVPNQGELTLPTSIGNTIINDGNPR-IN-TTGMEKSDEARAWFDSLTLNLEQGKSQNEKMWIATSEHPGDQNAKLWIKTANTTYSGRPYLQVVGFIDRAFPSFLAKVFKG-GVIAVYLSVILVVGRGLVRGIFTTSPSTVMFTELPNADHLLKICLDIYLVREAKDFMLEQDLFAKLIFLFRSPATLIEWTRMSK 1700

HSP 2 Score: 199.904 bits (507), Expect = 1.118e-50
Identity = 169/613 (27.57%), Postives = 277/613 (45.19%), Query Frame = 2 
Query: 2645 IIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCS---LTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLV---VCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLT--------SLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNI-----MLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMI-----SKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS-SVKSG-LHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECV---LXXXXXXXXXXXQRQAQHGKPELN----EHYLVVRSGDKYLF 4384
            +++KL +        +WRFFE H +KIV   I     N  NA  I L+IL+ +          +   S F C+   L  L KMIYQL  V +    +         N S   I   +W GL+K     + I+    V+V     A   +V Y QR +       +     +FP+      D SL N  +F I++ FYK GLE++ I   I    R+D  + +    L++F   +R    +IW+ Y++++ +L P+++   VGLPP  C +YP +          + NL   L L  Y     +  ++ DFF  +  + Q  VF  E     + Y  G    ++  E P+    DF+ TK SYVDY K  +F++ +W++L      G+   +LF LGY+I     LW G N+      LR   + +  WN ++ Y  F I  K  LQ+ GC ++ W        K  C +  LF + C+N    + ++L         C+   K G + +DV    F++ Q +IF +  F H +++   +   A+RGA L N+ +   ++EQ  +++     + +    I +  Q+Q + G  E +     +    R+GD Y+F
Sbjct:   69 LVKKLHKLANQTIELLWRFFEVHISKIVFVIIAIFIANNINALYIPLVILLSLAICLPSAADGIF--SLFMCAYLFLVALSKMIYQLDIVPEL---SQIDRGVGADNCSHGNISMPEWFGLKKEVEGTEPIYMLFGVIVSIIALAFQSIVIYRQRHYRASLGLPESMRAKVFPDFHHSHFDRSLKNAIQFLIDYGFYKFGLEITMIAIGIDIFNRMDALAAIQCFWLVLFALNKRVFVRRIWVFYVIYMAILYPLQFFSYVGLPPDSCIEYPWSYWIPSYSDDARFNLSYLLNLSIYGVNWPSAYLIGDFFVLLLASCQLAVFRREGEDNDSIYNDGNF--VIKPENPQY---DFIDTKKSYVDYFKSFVFHYGHWITLMSTLAAGIAGTSLFALGYIIFTLTMLWSGNNLYVMNSTLRSFEHTLKRWNALLGYTLFTITMKVCLQIFGCVFLSWFDQSGGWGKTLCIVRQLFSITCVNN---ECHVLKELEDFSKACAVETKEGNIGFDVIALSFLVFQIRIFHSWYFQHCMVEYRSEVILANRGAVLKNQLIEKEMKEQNEQQKAKFNDIRRRTEAIRERYQKQIERGAAERDFEPVTYGHAKRAGDYYMF 668
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Fly
Match: Piezo (gene:FBgn0264953 transcript:FBtr0335181)

HSP 1 Score: 489.189 bits (1258), Expect = 5.692e-139
Identity = 296/911 (32.49%), Postives = 488/911 (53.57%), Query Frame = 2 
Query: 5402 NLIVLINTWTKEYRRIRRTLDNEKRLVK---------LKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXXXXXXXXXLLAISLGN--VAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFI--SFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWR-----------------DHTEFAQDLEIVDKEQ---DGRNKIKSSYEESS-PTSNKWSCNPIYKMRR----------FYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPG-TDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDEN-----------DKKNLLKAIEANQSS--------YVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEAR--WWEIQEIVAGETYCS----NEKIPKQSHSNLTVFIFSERVSDNLFGHLFS---NYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
             L + +N +++ YR + R L  EK+ +K         L   + + + +   +E +  +        +S   +K   E+  E+E    R    ++ + + +    +  ++ +CY ++ +N +++ +L SLP P+MVFLW  LS+PRP+K FW+ LI YT+ +++IK IFQF  I  ++++  N    PL    I G+E   +YAI DLI LL +FLHR  LK+ GLW+                 D  + + +L   D  Q   D   K+     ++S P S ++S   I ++ R          F+S +   +     DVY  MFLC+F+ F +++FG+ +FG   T+S +    ++  NK+P+PF+ M++ QF+ I+IDRAL+LRK +  K IF  F V+ IH W+FF +P +T++ FNS   P + Y +KC Y  LS+YQ+KSGYP RILGNF T+ F+ +N+  FK YM +PFLYELR ++DW+  D+++ +F W+++ED+F  I++++C R+SE ++P +R   +   SK  +GG ++    IC WGPL L +        N P   + SI +G Y P+ Y  +  +++  +  + + +M   Y        ++  ++A DV  + + G+S  +W I PP  ++L   LR+  +LK        R++  +K  ++ V   +   LDE+            + + ++ I +N ++         VV I  + P+F+       +   ++L   +  Y  L + M ++NE    WWEI++      YC+    NE + K ++SN T  I     +D  F   FS     GIIG+Y  ++ +A R +++F    +  I  E+LP+VDR+L L  +IYLVRE   F LEE L AKL+FLYRS ET+IKWTR
Sbjct: 1649 TLTIRLNRFSRNYRFVNRILAGEKKTLKESSSLNRLGLSSAAAMFHFLKSNLERKQSI--------NSSPPAKGAGEFNLEEENFAQRDHHIIVEVLISSWYALLANTDLICYIVVFINQVVNASLISLPLPIMVFLWGTLSLPRPTKTFWVTLIAYTQAIVLIKCIFQFKLIWSNYHQLPNQ---PLTPAKIFGVENKAHYAIYDLILLLVLFLHRYLLKSQGLWKSGYKDTDNQFTKPTASIDERDDSDNLSQPDSRQLNDDAAQKLSLQVSQASLPGSPEFSKTGINQLERTKYTSSLYKFFFSLVHKSRL--ATDVYALMFLCDFVNFFVLLFGFTAFGTQQTESDEGVQTYLAENKVPIPFLIMLLVQFLLIVIDRALYLRKALVNKIIFHFFSVIGIHIWMFFVVPAVTERTFNSLAPPIIFYVIKCFYMLLSSYQIKSGYPKRILGNFFTKGFSMVNMIAFKVYMQIPFLYELRTILDWVCIDSTMTIFDWLKMEDIFSNIYLIRCTRQSETDFPAMRAQKKASLSKLIMGGTIVLLIVICIWGPLCLFALGNAVGTSNVPFHVSLSIRIGPYDPI-YTTNNYDSIFEINPEMYSQMTNAYIKEKQALTFIAGYDATDVAAVRLAGNSPSLWNIAPPDRQRLLNDLRNNHTLKARFSYSLTRKAP-AKGLKENVGDEHAISLDESFEGRAALIHMLSETHDVEPIYSNGTTNGTTPEVEEVVVIPGMIPKFIKVLNSGDAAVVSVLSPKHYDYRPLVIKMHRDNETNGLWWEIRD------YCNDTFYNETLSKFAYSNCTSGIVMYTFNDKKFPSTFSFLTAGGIIGLYTTFVLLASRFMKSFIGGQNRKIMFEDLPYVDRVLQLCLDIYLVREALEFALEEDLFAKLLFLYRSPETLIKWTR 2538

HSP 2 Score: 414.075 bits (1063), Expect = 9.178e-116
Identity = 310/1003 (30.91%), Postives = 481/1003 (47.96%), Query Frame = 2 
Query: 1607 RNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHK----WAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILND--SKFDQSSNADSEAYF---GNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQ-EPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNL------------------NIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKV----WRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSF-FWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWK----WTAVLVVCALWHVVKYHQRQF-YKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTS--LKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNN-YGGGRNRPILCN-----ELP-KTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNML---AVNRMHGDPCSSVKSG--LHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQA-------------QHGKP----------ELNEHYLVVRSGDKYLF 4384
            +NS++FT I MMAWS+ Y SW++F+LLLSA  LWM+P+ RKA +  SP IV YA  L+I QYIYG +L   ELP    TA    ++L +IGF +       P  PL V  +F+++FW+T R F  +      +++  L D  +    +  +   +Y    G   +   KK    +  +  + WI +    +   +I  E +  FRI YM L ++FL+ F  S   W K MY FW F+I Y++ +L+ IYTYQF++F   W +   +S  + +DIGLK Y+  DLF  L++P + +++ ++QV YFHK F+  S   + L G S +  P E                        ++ ++    + F   V    +I   K+K   E I+       WRF E H  K V        ++E    +I+ +   V+G    K   ++++    F  ++ VL KMIYQ++ ++    +  CS   T         +NA+WIGL K +     +      +   +V+  +  V+   Q Q   K      P T ++FP       +  L+ L K+ +NF FYK G+E+S I  V     R D+ ++VY + L++ L  +R  C+KIW  +  F  + +  +Y + VGLPP  C  +P       E +QRW  LP   +     K++ DF   V +  Q  +F IE     N+ Y GG NR ++ +      +P      DF S   +Y D LK+ +    YW +LA+VF  G     L  LGY+I AFI+LW G +  LR    +I  W  ++ +N   IL K + Q+ GC +M   ++K  CW++ + G+ C + +  ++ ML   A   +    C  +     L WD  CF FII Q +IF +  FCH++ D    N  ASRGA +I       I  +   E+ VL KIK K+++I   Q              +HG P          E+  H    R+GD Y+F
Sbjct:  509 QNSYIFTNILMMAWSIVYHSWLTFVLLLSANVLWMIPNQRKAMMRSSPFIVLYAEALLIAQYIYGMDLNNEELPTSVPTAG---INLQQIGFERPIENQMRPCVPLIVKTAFVLMFWVTSRQFFKEK--RDRRRDSTLADFIAPLQITVGSAGSSYLINDGKKTSKFLKKAGDVIKNLLVRLWIWLLVLVIFLCAITGENMTGFRICYMALFLFFLLVFQSSSKAWVKIMYGFWLFLIFYAMSILILIYTYQFDKFDTYWSDYLNVSATLQKDIGLKRYQTKDLFLHLVSPTIIVILTVIQVHYFHKRFIA-SLQQQPLAGGSAQQKPTETTALEPAPSKRRGSAGSLRKSQGPSAEAAPGATTDFETSVRDLVRISFRKIKNKSEYIFKNFKDVFWRFLELHIMKAVYIAAFVCSVSEVCVLHIIFVGFCVLGATSRKAVQVVISRLISFIVTVIVLSKMIYQIEYLSHSQHNVVCSDNRTA--------NNAEWIGLTKADKVTGGLMSLLRTYIIYMVIVTMHAVISLRQLQMRVKIGALNAPPTKLLFPNIIRADAEKDLVGLVKYLLNFGFYKFGIEISLIALVSTITYRQDIVAVVYALWLVVLLLLRRSQCAKIWGVFQAFFAISILTQYIVLVGLPPSSCLVFPWDEGPFGEGIQRWAMLPGALHFNHVPKLIFDFIVLVILNRQKSIFCIEQRYASNDDYPGGSNRSVIADIAQLGRVPFDNPTHDFCSYIRNYSDILKNGVLCGFYWFTLAVVFLAGTNIADLLALGYLIGAFIFLWQGSDFYLRPIHTIIFRWKWLLAFNVANILIKTSFQMAGCLFMT-QLTKDCCWLVHMLGITCTSNVLTEQIMLPEEAELALKPGECPKITHQVVLLWDTICFAFIIFQLRIFKSHYFCHIITDTKANNILASRGADIIESLRHKQIAHRHDHEKQVLHKIKRKMERIRATQQKMLRPLDKQTHFDEHGYPLPAPTVRRRKEIKLHPHATRAGDYYMF 1496
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Fly
Match: Piezo (gene:FBgn0264953 transcript:FBtr0347414)

HSP 1 Score: 489.189 bits (1258), Expect = 9.330e-139
Identity = 278/804 (34.58%), Postives = 446/804 (55.47%), Query Frame = 2 
Query: 5690 SEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFI--SFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDH-----TEFAQDLEIVDKEQDGRN---------------KIKSSYEESS-PTSNKWSCNPIYKMRR----------FYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPG-TDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDEN-----------DKKNLLKAIEANQSS--------YVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEAR--WWEIQEIVAGETYCS----NEKIPKQSHSNLTVFIFSERVSDNLFGHLFS---NYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            ++ +CY ++ +N +++ +L SLP P+MVFLW  LS+PRP+K FW+ LI YT+ +++IK IFQF  I  ++++  N    PL    I G+E   +YAI DLI LL +FLHR  LK+ GLW+        +F +    +D+  D  N               K+     ++S P S ++S   I ++ R          F+S +   +     DVY  MFLC+F+ F +++FG+ +FG   T+S +    ++  NK+P+PF+ M++ QF+ I+IDRAL+LRK +  K IF  F V+ IH W+FF +P +T++ FNS   P + Y +KC Y  LS+YQ+KSGYP RILGNF T+ F+ +N+  FK YM +PFLYELR ++DW+  D+++ +F W+++ED+F  I++++C R+SE ++P +R   +   SK  +GG ++    IC WGPL L +        N P   + SI +G Y P+ Y  +  +++  +  + + +M   Y        ++  ++A DV  + + G+S  +W I PP  ++L   LR+  +LK        R++  +K  ++ V   +   LDE+            + + ++ I +N ++         VV I  + P+F+       +   ++L   +  Y  L + M ++NE    WWEI++      YC+    NE + K ++SN T  I     +D  F   FS     GIIG+Y  ++ +A R +++F    +  I  E+LP+VDR+L L  +IYLVRE   F LEE L AKL+FLYRS ET+IKWTR
Sbjct: 2015 TDLICYIVVFINQVVNASLISLPLPIMVFLWGTLSLPRPTKTFWVTLIAYTQAIVLIKCIFQFKLIWSNYHQLPNQ---PLTPAKIFGVENKAHYAIYDLILLLVLFLHRYLLKSQGLWKSGYKDTDNQFTKPTASIDERDDSDNLSQPDSRQLNDDAAQKLSLQVSQASLPGSPEFSKTGINQLERTKYTSSLYKFFFSLVHKSRL--ATDVYALMFLCDFVNFFVLLFGFTAFGTQQTESDEGVQTYLAENKVPIPFLIMLLVQFLLIVIDRALYLRKALVNKIIFHFFSVIGIHIWMFFVVPAVTERTFNSLAPPIIFYVIKCFYMLLSSYQIKSGYPKRILGNFFTKGFSMVNMIAFKVYMQIPFLYELRTILDWVCIDSTMTIFDWLKMEDIFSNIYLIRCTRQSETDFPAMRAQKKASLSKLIMGGTIVLLIVICIWGPLCLFALGNAVGTSNVPFHVSLSIRIGPYDPI-YTTNNYDSIFEINPEMYSQMTNAYIKEKQALTFIAGYDATDVAAVRLAGNSPSLWNIAPPDRQRLLNDLRNNHTLKARFSYSLTRKAP-AKGLKENVGDEHAISLDESFEGRAALIHMLSETHDVEPIYSNGTTNGTTPEVEEVVVIPGMIPKFIKVLNSGDAAVVSVLSPKHYDYRPLVIKMHRDNETNGLWWEIRD------YCNDTFYNETLSKFAYSNCTSGIVMYTFNDKKFPSTFSFLTAGGIIGLYTTFVLLASRFMKSFIGGQNRKIMFEDLPYVDRVLQLCLDIYLVREALEFALEEDLFAKLLFLYRSPETLIKWTR 2805

HSP 2 Score: 430.639 bits (1106), Expect = 9.593e-121
Identity = 339/1193 (28.42%), Postives = 550/1193 (46.10%), Query Frame = 2 
Query:  863 FAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWI--DYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHK----WAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILND--SKFDQSSNADSEAYF---GNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQ-EPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNL------------------NIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKV----WRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSF-FWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWK----WTAVLVVCALWHVVKYHQRQF-YKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTS--LKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNN-YGGGRNRPILCN-----ELP-KTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNML---AVNRMHGDPCSSVKSG--LHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVL 4273
            FA ++ PS+    Y   FL   T+WA   + +   FA +   +++   +H   +   Q  ++Q +L +   ++RL+GL  L+ + C     V  Y ++     YL+P  + + Y+  A  T+   +      PR+      ++ S+ K       E            +GS +  SV++ G        +  L+S              +  + +  + ++LD                   +S+     +NS++FT I MMAWS+ Y SW++F+LLLSA  LWM+P+ RKA +  SP IV YA  L+I QYIYG +L   ELP    TA    ++L +IGF +       P  PL V  +F+++FW+T R F  +      +++  L D  +    +  +   +Y    G   +   KK    +  +  + WI +    +   +I  E +  FRI YM L ++FL+ F  S   W K MY FW F+I Y++ +L+ IYTYQF++F   W +   +S  + +DIGLK Y+  DLF  L++P + +++ ++QV YFHK F+  S   + L G S +  P E                        ++ ++    + F   V    +I   K+K   E I+       WRF E H  K V        ++E    +I+ +   V+G    K   ++++    F  ++ VL KMIYQ++ ++    +  CS   T         +NA+WIGL K +     +      +   +V+  +  V+   Q Q   K      P T ++FP       +  L+ L K+ +NF FYK G+E+S I  V     R D+ ++VY + L++ L  +R  C+KIW  +  F  + +  +Y + VGLPP  C  +P       E +QRW  LP   +     K++ DF   V +  Q  +F IE     N+ Y GG NR ++ +      +P      DF S   +Y D LK+ +    YW +LA+VF  G     L  LGY+I AFI+LW G +  LR    +I  W  ++ +N   IL K + Q+ GC +M   ++K  CW++ + G+ C + +  ++ ML   A   +    C  +     L WD  CF FII Q +IF +  FCH++ D    N  ASRGA +I       I  +   E+ VL
Sbjct:  223 FAAVLRPSVPGGFYFLIFLLSGTYWATC-QTLQRGFALLLRCVMVVLVLHSLSIVSYQTPWMQSHLNHTTLTARLIGLEPLIESYCSPDIRVFLYNNKLSLDSYLNPFALFFAYFALALTTKHLIK------PRL------VRQSTRKARTPQPLE------------SGSSVAPSVTQRGN-------DMQLES------------MEQRSEQENTTTSILDQISYG-------------FVSVGGFIYQNSYIFTNILMMAWSIVYHSWLTFVLLLSANVLWMIPNQRKAMMRSSPFIVLYAEALLIAQYIYGMDLNNEELPTSVPTAG---INLQQIGFERPIENQMRPCVPLIVKTAFVLMFWVTSRQFFKEK--RDRRRDSTLADFIAPLQITVGSAGSSYLINDGKKTSKFLKKAGDVIKNLLVRLWIWLLVLVIFLCAITGENMTGFRICYMALFLFFLLVFQSSSKAWVKIMYGFWLFLIFYAMSILILIYTYQFDKFDTYWSDYLNVSATLQKDIGLKRYQTKDLFLHLVSPTIIVILTVIQVHYFHKRFIA-SLQQQPLAGGSAQQKPTETTALEPAPSKRRGSAGSLRKSQGPSAEAAPGATTDFETSVRDLVRISFRKIKNKSEYIFKNFKDVFWRFLELHIMKAVYIAAFVCSVSEVCVLHIIFVGFCVLGATSRKAVQVVISRLISFIVTVIVLSKMIYQIEYLSHSQHNVVCSDNRT--------ANNAEWIGLTKADKVTGGLMSLLRTYIIYMVIVTMHAVISLRQLQMRVKIGALNAPPTKLLFPNIIRADAEKDLVGLVKYLLNFGFYKFGIEISLIALVSTITYRQDIVAVVYALWLVVLLLLRRSQCAKIWGVFQAFFAISILTQYIVLVGLPPSSCLVFPWDEGPFGEGIQRWAMLPGALHFNHVPKLIFDFIVLVILNRQKSIFCIEQRYASNDDYPGGSNRSVIADIAQLGRVPFDNPTHDFCSYIRNYSDILKNGVLCGFYWFTLAVVFLAGTNIADLLALGYLIGAFIFLWQGSDFYLRPIHTIIFRWKWLLAFNVANILIKTSFQMAGCLFMT-QLTKDCCWLVHMLGITCTSNVLTEQIMLPEEAELALKPGECPKITHQVVLLWDTICFAFIIFQLRIFKSHYFCHIITDTKANNILASRGADIIESLRHKQIAHRHDHEKQVL 1343
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Fly
Match: Piezo (gene:FBgn0264953 transcript:FBtr0335183)

HSP 1 Score: 488.419 bits (1256), Expect = 1.045e-138
Identity = 296/902 (32.82%), Postives = 484/902 (53.66%), Query Frame = 2 
Query: 5402 NLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXXXXXXXXXLLAISLGN--VAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFI--SFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWR-----------------DHTEFAQDLEIVDKEQ---DGRNKIKSSYEESS-PTSNKWSCNPIYKMRR----------FYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPG-TDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDEN-----------DKKNLLKAIEANQSS--------YVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEAR--WWEIQEIVAGETYCS----NEKIPKQSHSNLTVFIFSERVSDNLFGHLFS---NYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
             L + +N +++ YR + R L  EK+ +K        +    R+ L +         S    N ++  E+  E+E    R    ++ + + +    +  ++ +CY ++ +N +++ +L SLP P+MVFLW  LS+PRP+K FW+ LI YT+ +++IK IFQF  I  ++++  N    PL    I G+E   +YAI DLI LL +FLHR  LK+ GLW+                 D  + + +L   D  Q   D   K+     ++S P S ++S   I ++ R          F+S +   +     DVY  MFLC+F+ F +++FG+ +FG   T+S +    ++  NK+P+PF+ M++ QF+ I+IDRAL+LRK +  K IF  F V+ IH W+FF +P +T++ FNS   P + Y +KC Y  LS+YQ+KSGYP RILGNF T+ F+ +N+  FK YM +PFLYELR ++DW+  D+++ +F W+++ED+F  I++++C R+SE ++P +R   +   SK  +GG ++    IC WGPL L +        N P   + SI +G Y P+ Y  +  +++  +  + + +M   Y        ++  ++A DV  + + G+S  +W I PP  ++L   LR+  +LK        R++  +K  ++ V   +   LDE+            + + ++ I +N ++         VV I  + P+F+       +   ++L   +  Y  L + M ++NE    WWEI++      YC+    NE + K ++SN T  I     +D  F   FS     GIIG+Y  ++ +A R +++F    +  I  E+LP+VDR+L L  +IYLVRE   F LEE L AKL+FLYRS ET+IKWTR
Sbjct: 1623 TLTIRLNRFSRNYRFVNRILAGEKKTLK-------ESSSLNRLGLSSAAAMFHFLKS----NLESAGEFNLEEENFAQRDHHIIVEVLISSWYALLANTDLICYIVVFINQVVNASLISLPLPIMVFLWGTLSLPRPTKTFWVTLIAYTQAIVLIKCIFQFKLIWSNYHQLPNQ---PLTPAKIFGVENKAHYAIYDLILLLVLFLHRYLLKSQGLWKSGYKDTDNQFTKPTASIDERDDSDNLSQPDSRQLNDDAAQKLSLQVSQASLPGSPEFSKTGINQLERTKYTSSLYKFFFSLVHKSRL--ATDVYALMFLCDFVNFFVLLFGFTAFGTQQTESDEGVQTYLAENKVPIPFLIMLLVQFLLIVIDRALYLRKALVNKIIFHFFSVIGIHIWMFFVVPAVTERTFNSLAPPIIFYVIKCFYMLLSSYQIKSGYPKRILGNFFTKGFSMVNMIAFKVYMQIPFLYELRTILDWVCIDSTMTIFDWLKMEDIFSNIYLIRCTRQSETDFPAMRAQKKASLSKLIMGGTIVLLIVICIWGPLCLFALGNAVGTSNVPFHVSLSIRIGPYDPI-YTTNNYDSIFEINPEMYSQMTNAYIKEKQALTFIAGYDATDVAAVRLAGNSPSLWNIAPPDRQRLLNDLRNNHTLKARFSYSLTRKAP-AKGLKENVGDEHAISLDESFEGRAALIHMLSETHDVEPIYSNGTTNGTTPEVEEVVVIPGMIPKFIKVLNSGDAAVVSVLSPKHYDYRPLVIKMHRDNETNGLWWEIRD------YCNDTFYNETLSKFAYSNCTSGIVMYTFNDKKFPSTFSFLTAGGIIGLYTTFVLLASRFMKSFIGGQNRKIMFEDLPYVDRVLQLCLDIYLVREALEFALEEDLFAKLLFLYRSPETLIKWTR 2500

HSP 2 Score: 434.876 bits (1117), Expect = 3.213e-122
Identity = 355/1253 (28.33%), Postives = 573/1253 (45.73%), Query Frame = 2 
Query:  863 FAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWI--DYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHK----WAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILND--SKFDQSSNADSEAYF---GNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQ-EPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNL------------------NIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKV----WRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSF-FWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWK----WTAVLVVCALWHVVKYHQRQF-YKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTS--LKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNN-YGGGRNRPILCN-----ELP-KTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNML---AVNRMHGDPCSSVKSG--LHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQA-------------QHGKP----------ELNEHYLVVRSGDKYLF 4384
            FA ++ PS+    Y   FL   T+WA   + +   FA +   +++   +H   +   Q  ++Q +L +   ++RL+GL  L+ + C     V  Y ++     YL+P  + + Y+  A  T+   +      PR+      ++ S+ K       E            +GS +  SV++ G        +  L+S              +  + +  + ++LD                   +S+     +NS++FT I MMAWS+ Y SW++F+LLLSA  LWM+P+ RKA +  SP IV YA  L+I QYIYG +L   ELP    TA    ++L +IGF +       P  PL V  +F+++FW+T R F  +      +++  L D  +    +  +   +Y    G   +   KK    +  +  + WI +    +   +I  E +  FRI YM L ++FL+ F  S   W K MY FW F+I Y++ +L+ IYTYQF++F   W +   +S  + +DIGLK Y+  DLF  L++P + +++ ++QV YFHK F+  S   + L G S +  P E                        ++ ++    + F   V    +I   K+K   E I+       WRF E H  K V        ++E    +I+ +   V+G    K   ++++    F  ++ VL KMIYQ++ ++    +  CS   T         +NA+WIGL K +     +      +   +V+  +  V+   Q Q   K      P T ++FP       +  L+ L K+ +NF FYK G+E+S I  V     R D+ ++VY + L++ L  +R  C+KIW  +  F  + +  +Y + VGLPP  C  +P       E +QRW  LP   +     K++ DF   V +  Q  +F IE     N+ Y GG NR ++ +      +P      DF S   +Y D LK+ +    YW +LA+VF  G     L  LGY+I AFI+LW G +  LR    +I  W  ++ +N   IL K + Q+ GC +M   ++K  CW++ + G+ C + +  ++ ML   A   +    C  +     L WD  CF FII Q +IF +  FCH++ D    N  ASRGA +I       I  +   E+ VL KIK K+++I   Q              +HG P          E+  H    R+GD Y+F
Sbjct:  223 FAAVLRPSVPGGFYFLIFLLSGTYWATC-QTLQRGFALLLRCVMVVLVLHSLSIVSYQTPWMQSHLNHTTLTARLIGLEPLIESYCSPDIRVFLYNNKLSLDSYLNPFALFFAYFALALTTKHLIK------PRL------VRQSTRKARTPQPLE------------SGSSVAPSVTQRGN-------DMQLES------------MEQRSEQENTTTSILDQISYG-------------FVSVGGFIYQNSYIFTNILMMAWSIVYHSWLTFVLLLSANVLWMIPNQRKAMMRSSPFIVLYAEALLIAQYIYGMDLNNEELPTSVPTAG---INLQQIGFERPIENQMRPCVPLIVKTAFVLMFWVTSRQFFKEK--RDRRRDSTLADFIAPLQITVGSAGSSYLINDGKKTSKFLKKAGDVIKNLLVRLWIWLLVLVIFLCAITGENMTGFRICYMALFLFFLLVFQSSSKAWVKIMYGFWLFLIFYAMSILILIYTYQFDKFDTYWSDYLNVSATLQKDIGLKRYQTKDLFLHLVSPTIIVILTVIQVHYFHKRFIA-SLQQQPLAGGSAQQKPTETTALEPAPSKRRGSAGSLRKSQGPSAEAAPGATTDFETSVRDLVRISFRKIKNKSEYIFKNFKDVFWRFLELHIMKAVYIAAFVCSVSEVCVLHIIFVGFCVLGATSRKAVQVVISRLISFIVTVIVLSKMIYQIEYLSHSQHNVVCSDNRTA--------NNAEWIGLTKADKVTGGLMSLLRTYIIYMVIVTMHAVISLRQLQMRVKIGALNAPPTKLLFPNIIRADAEKDLVGLVKYLLNFGFYKFGIEISLIALVSTITYRQDIVAVVYALWLVVLLLLRRSQCAKIWGVFQAFFAISILTQYIVLVGLPPSSCLVFPWDEGPFGEGIQRWAMLPGALHFNHVPKLIFDFIVLVILNRQKSIFCIEQRYASNDDYPGGSNRSVIADIAQLGRVPFDNPTHDFCSYIRNYSDILKNGVLCGFYWFTLAVVFLAGTNIADLLALGYLIGAFIFLWQGSDFYLRPIHTIIFRWKWLLAFNVANILIKTSFQMAGCLFMT-QLTKDCCWLVHMLGITCTSNVLTEQIMLPEEAELALKPGECPKITHQVVLLWDTICFAFIIFQLRIFKSHYFCHIITDTKANNILASRGADIIESLRHKQIAHRHDHEKQVLHKIKRKMERIRATQQKMLRPLDKQTHFDEHGYPLPAPTVRRRKEIKLHPHATRAGDYYMF 1403
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Fly
Match: Piezo (gene:FBgn0264953 transcript:FBtr0335180)

HSP 1 Score: 488.419 bits (1256), Expect = 1.178e-138
Identity = 278/804 (34.58%), Postives = 446/804 (55.47%), Query Frame = 2 
Query: 5690 SEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFI--SFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRD-----HTEFAQDLEIVDKEQDGRN---------------KIKSSYEESS-PTSNKWSCNPIYKMRR----------FYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPG-TDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDEN-----------DKKNLLKAIEANQSS--------YVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEAR--WWEIQEIVAGETYCS----NEKIPKQSHSNLTVFIFSERVSDNLFGHLFS---NYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            ++ +CY ++ +N +++ +L SLP P+MVFLW  LS+PRP+K FW+ LI YT+ +++IK IFQF  I  ++++  N    PL    I G+E   +YAI DLI LL +FLHR  LK+ GLW+        +F +    +D+  D  N               K+     ++S P S ++S   I ++ R          F+S +   +     DVY  MFLC+F+ F +++FG+ +FG   T+S +    ++  NK+P+PF+ M++ QF+ I+IDRAL+LRK +  K IF  F V+ IH W+FF +P +T++ FNS   P + Y +KC Y  LS+YQ+KSGYP RILGNF T+ F+ +N+  FK YM +PFLYELR ++DW+  D+++ +F W+++ED+F  I++++C R+SE ++P +R   +   SK  +GG ++    IC WGPL L +        N P   + SI +G Y P+ Y  +  +++  +  + + +M   Y        ++  ++A DV  + + G+S  +W I PP  ++L   LR+  +LK        R++  +K  ++ V   +   LDE+            + + ++ I +N ++         VV I  + P+F+       +   ++L   +  Y  L + M ++NE    WWEI++      YC+    NE + K ++SN T  I     +D  F   FS     GIIG+Y  ++ +A R +++F    +  I  E+LP+VDR+L L  +IYLVRE   F LEE L AKL+FLYRS ET+IKWTR
Sbjct: 1798 TDLICYIVVFINQVVNASLISLPLPIMVFLWGTLSLPRPTKTFWVTLIAYTQAIVLIKCIFQFKLIWSNYHQLPNQ---PLTPAKIFGVENKAHYAIYDLILLLVLFLHRYLLKSQGLWKSGYKDTDNQFTKPTASIDERDDSDNLSQPDSRQLNDDAAQKLSLQVSQASLPGSPEFSKTGINQLERTKYTSSLYKFFFSLVHKSRL--ATDVYALMFLCDFVNFFVLLFGFTAFGTQQTESDEGVQTYLAENKVPIPFLIMLLVQFLLIVIDRALYLRKALVNKIIFHFFSVIGIHIWMFFVVPAVTERTFNSLAPPIIFYVIKCFYMLLSSYQIKSGYPKRILGNFFTKGFSMVNMIAFKVYMQIPFLYELRTILDWVCIDSTMTIFDWLKMEDIFSNIYLIRCTRQSETDFPAMRAQKKASLSKLIMGGTIVLLIVICIWGPLCLFALGNAVGTSNVPFHVSLSIRIGPYDPI-YTTNNYDSIFEINPEMYSQMTNAYIKEKQALTFIAGYDATDVAAVRLAGNSPSLWNIAPPDRQRLLNDLRNNHTLKARFSYSLTRKAP-AKGLKENVGDEHAISLDESFEGRAALIHMLSETHDVEPIYSNGTTNGTTPEVEEVVVIPGMIPKFIKVLNSGDAAVVSVLSPKHYDYRPLVIKMHRDNETNGLWWEIRD------YCNDTFYNETLSKFAYSNCTSGIVMYTFNDKKFPSTFSFLTAGGIIGLYTTFVLLASRFMKSFIGGQNRKIMFEDLPYVDRVLQLCLDIYLVREALEFALEEDLFAKLLFLYRSPETLIKWTR 2588

HSP 2 Score: 441.039 bits (1133), Expect = 4.837e-124
Identity = 360/1256 (28.66%), Postives = 581/1256 (46.26%), Query Frame = 2 
Query:  863 FAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWI--DYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQ---TGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHK----WAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILND--SKFDQSSNADSEAYF---GNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQ-EPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNL------------------NIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKV----WRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSF-FWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWK----WTAVLVVCALWHVVKYHQRQF-YKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTS--LKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNN-YGGGRNRPILCN-----ELP-KTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNML---AVNRMHGDPCSSVKSG--LHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQA-------------QHGKP----------ELNEHYLVVRSGDKYLF 4384
            FA ++ PS+    Y   FL   T+WA   + +   FA +   +++   +H   +   Q  ++Q +L +   ++RL+GL  L+ + C     V  Y ++     YL+P  + + Y+  A  T+   +      PRV S + D + ++L +  E  P ++    K    Q   +GS +  SV++ G        +  L+S              +  + +  + ++LD                   +S+     +NS++FT I MMAWS+ Y SW++F+LLLSA  LWM+P+ RKA +  SP IV YA  L+I QYIYG +L   ELP    TA    ++L +IGF +       P  PL V  +F+++FW+T R F  +      +++  L D  +    +  +   +Y    G   +   KK    +  +  + WI +    +   +I  E +  FRI YM L ++FL+ F  S   W K MY FW F+I Y++ +L+ IYTYQF++F   W +   +S  + +DIGLK Y+  DLF  L++P + +++ ++QV YFHK F+  S   + L G S +  P E                        ++ ++    + F   V    +I   K+K   E I+       WRF E H  K V        ++E    +I+ +   V+G    K   ++++    F  ++ VL KMIYQ++ ++    +  CS   T         +NA+WIGL K +     +      +   +V+  +  V+   Q Q   K      P T ++FP       +  L+ L K+ +NF FYK G+E+S I  V     R D+ ++VY + L++ L  +R  C+KIW  +  F  + +  +Y + VGLPP  C  +P       E +QRW  LP   +     K++ DF   V +  Q  +F IE     N+ Y GG NR ++ +      +P      DF S   +Y D LK+ +    YW +LA+VF  G     L  LGY+I AFI+LW G +  LR    +I  W  ++ +N   IL K + Q+ GC +M   ++K  CW++ + G+ C + +  ++ ML   A   +    C  +     L WD  CF FII Q +IF +  FCH++ D    N  ASRGA +I       I  +   E+ VL KIK K+++I   Q              +HG P          E+  H    R+GD Y+F
Sbjct:  223 FAAVLRPSVPGGFYFLIFLLSGTYWATC-QTLQRGFALLLRCVMVVLVLHSLSIVSYQTPWMQSHLNHTTLTARLIGLEPLIESYCSPDIRVFLYNNKLSLDSYLNPFALFFAYFALALTTKHLIK------PRV-SLRRD-QRATLNEPTETTPLVRQSTRKARTPQPLESGSSVAPSVTQRGN-------DMQLES------------MEQRSEQENTTTSILDQISYG-------------FVSVGGFIYQNSYIFTNILMMAWSIVYHSWLTFVLLLSANVLWMIPNQRKAMMRSSPFIVLYAEALLIAQYIYGMDLNNEELPTSVPTAG---INLQQIGFERPIENQMRPCVPLIVKTAFVLMFWVTSRQFFKEK--RDRRRDSTLADFIAPLQITVGSAGSSYLINDGKKTSKFLKKAGDVIKNLLVRLWIWLLVLVIFLCAITGENMTGFRICYMALFLFFLLVFQSSSKAWVKIMYGFWLFLIFYAMSILILIYTYQFDKFDTYWSDYLNVSATLQKDIGLKRYQTKDLFLHLVSPTIIVILTVIQVHYFHKRFIA-SLQQQPLAGGSAQQKPTETTALEPAPSKRRGSAGSLRKSQGPSAEAAPGATTDFETSVRDLVRISFRKIKNKSEYIFKNFKDVFWRFLELHIMKAVYIAAFVCSVSEVCVLHIIFVGFCVLGATSRKAVQVVISRLISFIVTVIVLSKMIYQIEYLSHSQHNVVCSDNRTA--------NNAEWIGLTKADKVTGGLMSLLRTYIIYMVIVTMHAVISLRQLQMRVKIGALNAPPTKLLFPNIIRADAEKDLVGLVKYLLNFGFYKFGIEISLIALVSTITYRQDIVAVVYALWLVVLLLLRRSQCAKIWGVFQAFFAISILTQYIVLVGLPPSSCLVFPWDEGPFGEGIQRWAMLPGALHFNHVPKLIFDFIVLVILNRQKSIFCIEQRYASNDDYPGGSNRSVIADIAQLGRVPFDNPTHDFCSYIRNYSDILKNGVLCGFYWFTLAVVFLAGTNIADLLALGYLIGAFIFLWQGSDFYLRPIHTIIFRWKWLLAFNVANILIKTSFQMAGCLFMT-QLTKDCCWLVHMLGITCTSNVLTEQIMLPEEAELALKPGECPKITHQVVLLWDTICFAFIIFQLRIFKSHYFCHIITDTKANNILASRGADIIESLRHKQIAHRHDHEKQVLHKIKRKMERIRATQQKMLRPLDKQTHFDEHGYPLPAPTVRRRKEIKLHPHATRAGDYYMF 1422
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Fly
Match: Piezo (gene:FBgn0264953 transcript:FBtr0347415)

HSP 1 Score: 488.804 bits (1257), Expect = 1.509e-138
Identity = 279/804 (34.70%), Postives = 446/804 (55.47%), Query Frame = 2 
Query: 5690 SEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFI--SFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWR-----------------DHTEFAQDLEIVDKEQ---DGRNKIKSSYEESS-PTSNKWSCNPIYKMRR----------FYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPG-TDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDEN-----------DKKNLLKAIEANQSS--------YVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEAR--WWEIQEIVAGETYCS----NEKIPKQSHSNLTVFIFSERVSDNLFGHLFS---NYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            ++ +CY ++ +N +++ +L SLP P+MVFLW  LS+PRP+K FW+ LI YT+ +++IK IFQF  I  ++++  N    PL    I G+E   +YAI DLI LL +FLHR  LK+ GLW+                 D  + + +L   D  Q   D   K+     ++S P S ++S   I ++ R          F+S +   +     DVY  MFLC+F+ F +++FG+ +FG   T+S +    ++  NK+P+PF+ M++ QF+ I+IDRAL+LRK +  K IF  F V+ IH W+FF +P +T++ FNS   P + Y +KC Y  LS+YQ+KSGYP RILGNF T+ F+ +N+  FK YM +PFLYELR ++DW+  D+++ +F W+++ED+F  I++++C R+SE ++P +R   +   SK  +GG ++    IC WGPL L +        N P   + SI +G Y P+ Y  +  +++  +  + + +M   Y        ++  ++A DV  + + G+S  +W I PP  ++L   LR+  +LK        R++  +K  ++ V   +   LDE+            + + ++ I +N ++         VV I  + P+F+       +   ++L   +  Y  L + M ++NE    WWEI++      YC+    NE + K ++SN T  I     +D  F   FS     GIIG+Y  ++ +A R +++F    +  I  E+LP+VDR+L L  +IYLVRE   F LEE L AKL+FLYRS ET+IKWTR
Sbjct: 2150 TDLICYIVVFINQVVNASLISLPLPIMVFLWGTLSLPRPTKTFWVTLIAYTQAIVLIKCIFQFKLIWSNYHQLPNQ---PLTPAKIFGVENKAHYAIYDLILLLVLFLHRYLLKSQGLWKSGYKDTDNQFTKPTASIDERDDSDNLSQPDSRQLNDDAAQKLSLQVSQASLPGSPEFSKTGINQLERTKYTSSLYKFFFSLVHKSRL--ATDVYALMFLCDFVNFFVLLFGFTAFGTQQTESDEGVQTYLAENKVPIPFLIMLLVQFLLIVIDRALYLRKALVNKIIFHFFSVIGIHIWMFFVVPAVTERTFNSLAPPIIFYVIKCFYMLLSSYQIKSGYPKRILGNFFTKGFSMVNMIAFKVYMQIPFLYELRTILDWVCIDSTMTIFDWLKMEDIFSNIYLIRCTRQSETDFPAMRAQKKASLSKLIMGGTIVLLIVICIWGPLCLFALGNAVGTSNVPFHVSLSIRIGPYDPI-YTTNNYDSIFEINPEMYSQMTNAYIKEKQALTFIAGYDATDVAAVRLAGNSPSLWNIAPPDRQRLLNDLRNNHTLKARFSYSLTRKAP-AKGLKENVGDEHAISLDESFEGRAALIHMLSETHDVEPIYSNGTTNGTTPEVEEVVVIPGMIPKFIKVLNSGDAAVVSVLSPKHYDYRPLVIKMHRDNETNGLWWEIRD------YCNDTFYNETLSKFAYSNCTSGIVMYTFNDKKFPSTFSFLTAGGIIGLYTTFVLLASRFMKSFIGGQNRKIMFEDLPYVDRVLQLCLDIYLVREALEFALEEDLFAKLLFLYRSPETLIKWTR 2940

HSP 2 Score: 430.639 bits (1106), Expect = 1.037e-120
Identity = 339/1193 (28.42%), Postives = 550/1193 (46.10%), Query Frame = 2 
Query:  863 FAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWI--DYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHK----WAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILND--SKFDQSSNADSEAYF---GNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQ-EPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNL------------------NIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKV----WRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSF-FWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWK----WTAVLVVCALWHVVKYHQRQF-YKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTS--LKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNN-YGGGRNRPILCN-----ELP-KTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNML---AVNRMHGDPCSSVKSG--LHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVL 4273
            FA ++ PS+    Y   FL   T+WA   + +   FA +   +++   +H   +   Q  ++Q +L +   ++RL+GL  L+ + C     V  Y ++     YL+P  + + Y+  A  T+   +      PR+      ++ S+ K       E            +GS +  SV++ G        +  L+S              +  + +  + ++LD                   +S+     +NS++FT I MMAWS+ Y SW++F+LLLSA  LWM+P+ RKA +  SP IV YA  L+I QYIYG +L   ELP    TA    ++L +IGF +       P  PL V  +F+++FW+T R F  +      +++  L D  +    +  +   +Y    G   +   KK    +  +  + WI +    +   +I  E +  FRI YM L ++FL+ F  S   W K MY FW F+I Y++ +L+ IYTYQF++F   W +   +S  + +DIGLK Y+  DLF  L++P + +++ ++QV YFHK F+  S   + L G S +  P E                        ++ ++    + F   V    +I   K+K   E I+       WRF E H  K V        ++E    +I+ +   V+G    K   ++++    F  ++ VL KMIYQ++ ++    +  CS   T         +NA+WIGL K +     +      +   +V+  +  V+   Q Q   K      P T ++FP       +  L+ L K+ +NF FYK G+E+S I  V     R D+ ++VY + L++ L  +R  C+KIW  +  F  + +  +Y + VGLPP  C  +P       E +QRW  LP   +     K++ DF   V +  Q  +F IE     N+ Y GG NR ++ +      +P      DF S   +Y D LK+ +    YW +LA+VF  G     L  LGY+I AFI+LW G +  LR    +I  W  ++ +N   IL K + Q+ GC +M   ++K  CW++ + G+ C + +  ++ ML   A   +    C  +     L WD  CF FII Q +IF +  FCH++ D    N  ASRGA +I       I  +   E+ VL
Sbjct:  223 FAAVLRPSVPGGFYFLIFLLSGTYWATC-QTLQRGFALLLRCVMVVLVLHSLSIVSYQTPWMQSHLNHTTLTARLIGLEPLIESYCSPDIRVFLYNNKLSLDSYLNPFALFFAYFALALTTKHLIK------PRL------VRQSTRKARTPQPLE------------SGSSVAPSVTQRGN-------DMQLES------------MEQRSEQENTTTSILDQISYG-------------FVSVGGFIYQNSYIFTNILMMAWSIVYHSWLTFVLLLSANVLWMIPNQRKAMMRSSPFIVLYAEALLIAQYIYGMDLNNEELPTSVPTAG---INLQQIGFERPIENQMRPCVPLIVKTAFVLMFWVTSRQFFKEK--RDRRRDSTLADFIAPLQITVGSAGSSYLINDGKKTSKFLKKAGDVIKNLLVRLWIWLLVLVIFLCAITGENMTGFRICYMALFLFFLLVFQSSSKAWVKIMYGFWLFLIFYAMSILILIYTYQFDKFDTYWSDYLNVSATLQKDIGLKRYQTKDLFLHLVSPTIIVILTVIQVHYFHKRFIA-SLQQQPLAGGSAQQKPTETTALEPAPSKRRGSAGSLRKSQGPSAEAAPGATTDFETSVRDLVRISFRKIKNKSEYIFKNFKDVFWRFLELHIMKAVYIAAFVCSVSEVCVLHIIFVGFCVLGATSRKAVQVVISRLISFIVTVIVLSKMIYQIEYLSHSQHNVVCSDNRT--------ANNAEWIGLTKADKVTGGLMSLLRTYIIYMVIVTMHAVISLRQLQMRVKIGALNAPPTKLLFPNIIRADAEKDLVGLVKYLLNFGFYKFGIEISLIALVSTITYRQDIVAVVYALWLVVLLLLRRSQCAKIWGVFQAFFAISILTQYIVLVGLPPSSCLVFPWDEGPFGEGIQRWAMLPGALHFNHVPKLIFDFIVLVILNRQKSIFCIEQRYASNDDYPGGSNRSVIADIAQLGRVPFDNPTHDFCSYIRNYSDILKNGVLCGFYWFTLAVVFLAGTNIADLLALGYLIGAFIFLWQGSDFYLRPIHTIIFRWKWLLAFNVANILIKTSFQMAGCLFMT-QLTKDCCWLVHMLGITCTSNVLTEQIMLPEEAELALKPGECPKITHQVVLLWDTICFAFIIFQLRIFKSHYFCHIITDTKANNILASRGADIIESLRHKQIAHRHDHEKQVL 1343
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Zebrafish
Match: piezo2a.2 (piezo-type mechanosensitive ion channel component 2a, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-131119-76])

HSP 1 Score: 451.44 bits (1160), Expect = 2.771e-136
Identity = 231/590 (39.15%), Postives = 360/590 (61.02%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERR-SSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKK-----ENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHN 7921
            +R+F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P  F+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T+++F+     QL YFVKCIYF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IFVLKCWR SE  YP  RG  ++   KY +GG+++       W PL   S + +   V N P++ + +I++GG+ P+F   +++N LK L +  F      Y        +L ++ A DVT   ++GSS+ +WTI+PPS + L   L   +   + M    +R  S  +K+   M +H     LD   ++ L+  +   +++ V+ I+ +FP F+ A   + ++    L + +  Y ++ L +++     E+   WW + E+ + +         +Q  + L +++FS++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR  
Sbjct:  272 IRQFFYSLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPEAFLVMVLIQFGTMVVDRALYLRKTVMGKVIFQVILVFGIHFWMFFILPGVTERRFSQNTVAQLWYFVKCIYFGLSAYQIRCGYPTRVLGNFLTKSYNYLNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFVLKCWRESEKRYPQPRGQKKKKVVKYGMGGMIVMLLICIVWFPLLFMSLVKSVAGVVNKPLDVSVTITLGGFQPIFTMSAQQNQLKELTESDFKNFINSYNYVPSAMQFLEAYRAEDVTVAELEGSSNSLWTISPPSRKNLMDVLSKEDQFPVTMTWSIQRNLSLGAKSEFAMDKHVT--YLDIKTRQELIALLNGTRNTPVL-IEQVFPCFIRAPSDSNAKPIEQLYE-DGVYKSIQLDLERSANSSEDLQEWWIVDELRSAQK--------QQREAGLQLYVFSDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPCVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTREK 847

HSP 2 Score: 119.013 bits (297), Expect = 3.737e-26
Identity = 73/168 (43.45%), Postives = 102/168 (60.71%), Query Frame = 2 
Query: 5654 LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTN-DRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWS 6154
            L  SL NV + +S+ VCY ++ILNHM+S ++ +L  P+++FLWAMLSVPRPSK FW+  I YTE+ IVIKY FQF F  FN++   D+  P   P IIG+EK + Y   DL+QLL +F HR  LK  GLW +     +   +      G  +    + E SP  + ++
Sbjct:   23 LCYSLYNVLVSHSQMVCYLVIILNHMISASVATLVLPVLIFLWAMLSVPRPSKRFWMTAIVYTEVTIVIKYFFQFGFFPFNQSIEVDKSKPFHPPNIIGVEKKEGYVHYDLVQLLALFFHRSILKCYGLWDEE----EPRSVSPHTHSGAEEKAECFSEKSPVEDTYT 186
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Zebrafish
Match: LO018508.1 (pep chromosome:GRCz11:2:54327160:54353625:1 gene:ENSDARG00000112723.1 transcript:ENSDART00000182320.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:LO018508.1)

HSP 1 Score: 441.039 bits (1133), Expect = 3.894e-136
Identity = 239/589 (40.58%), Postives = 357/589 (60.61%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFI-GTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRST-ESLKINMQAICERR-SSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEA----RWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRH 7918
            +R+F+  + +P+++   DVYV MFL + + F+II+FG+ +FG     AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP IT+++F+     QL YFVKCIYF LSAYQ++ GYP RILGNFLT+ +NY NLFLF+G+ ++PFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++   KY +GG+++       W PL   S +     V N P+E + S+++GG  P+F   +++N++KS+  +                 +L S+   D+T   ++GSS+ +WTI+PPS E LK  L  T E   +      +R  S  +K    M ++    +LD+  +K L   +    SS  V I  IFPR++ A   + S A  + + +N+ Y+++TL + K+N +     WW + +  +G        +P  + S L ++I S++VS    G L + YGI+G+Y + + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR 
Sbjct:   26 IRQFFYNLVHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHQGGADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVVGKVIFQVILVFGIHFWMFFILPGITERRFSQNTIAQLWYFVKCIYFGLSAYQIRCGYPTRILGNFLTKSYNYANLFLFQGFRLIPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIVMLLICIVWFPLLFMSLVKSVAGVVNKPLEVSVSLTLGGLQPIFTMSAQQNHIKSVTGNAI--------------MFLESYFPEDLTIAHLEGSSNSLWTISPPSKENLKNMLNDTREPFPLTFTWSIQRNLSLGAKAETAMGKY--FIELDDETRKGLTDQL--GNSSQRVTIKKIFPRYIRA--PSDSNAKPIDQLYNE-YMDITLFLNKKNSSEGVQEWWIVNQTDSG-------PLPGLNGSGLQIYIISDQVSPPSLGFL-AGYGIMGLYMSVVLVIGKFVREFFSGISHTIMFEELPNVDRILKLCTDIFLVRETGELDLEEDLYAKLIFLYRSPETMIKWTRE 584
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Zebrafish
Match: piezo1 (piezo-type mechanosensitive ion channel component 1 [Source:ZFIN;Acc:ZDB-GENE-041111-255])

HSP 1 Score: 462.996 bits (1190), Expect = 7.388e-131
Identity = 333/1166 (28.56%), Postives = 560/1166 (48.03%), Query Frame = 2 
Query:  848 VVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYT-HRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNL-TELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKL----KQFFEV---IYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN---------FNKSM--DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKI-CSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-----LTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGG-GRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEE 4264
            V +   AGI  PS  ++ Y   F+G+CT+WAC   +    F  + + +  ++  H+  LYL Q  F Q         +RL GL  LV     T  EV   T + W  Y++P I++ +Y       +     G E   R+   +        +QS+E D +              +LLT+  S   E      P   ++  +  DI              GPS     D+              PL L +    ++ S++   IAMM WS+TY SW++F+LLL +C +WM+   ++   Y SP I+ Y   L  +QY++  +L TELP+        ++ L ++G  +   P   L  ++ F + FWL LR  + DT          L +    +S+  +           I K     +  +  KYWI VC    + VS    +V ++IVYMLL +  +  +   YS WR+ +  FWW V+ Y+++VL+ IYT+QF  FP  W N TG +E+ L D+GL+T++ S+LF  ++ P  FL+  I+Q+ YFHKPF+K++ +         E  P E+ L +          S   E + S + +++++L    ++F +    + + +WR  E H  KIV F +V   + E +A N+VL++L     P+ +   +    S  W  + ++ KM+YQL  VN   +S NC+    N          N ++    +D A W G+ K +    ++     VL++      V  HQ   Y+    + P   +IFP+ T  ++D  L++  K+ +N++FYK GLE+ F++TV V   R++   +++   L+  +  +R+   + IW  Y LFL V +  +Y +CVG+PP LC  YP       ++   L +W++LP +   P++K +++DF   +  + Q+ VF  E        GG  R+ P     +      +F++ + SY+D  K  +F + +W  L++VF TG   I++F LGY++  F +L  G  ++ +     +  W+ +I YN  VI+SK  L ++ C ++  M  K FCW+I LF + C     +D   +  N+    P    ++G+ WD  CF F++LQR++F++  F HV  DL    R ASRG  L    ++ ++   +  E 
Sbjct:  208 VTLLALAGITLPSAFSAFYFLLFIGVCTWWACHFPISHLGFNALCVMVAFFTGGHLVCLYLYQSSFAQAMFSPAGLWARLFGLKDLVTPGNCTTFEVTLNTQYDWPVYVNPGILLLLYISVTIVLKINSNTGEEVELRLWEAR--------RQSSEDDTK-------------QTLLTTVDSTLSESHITKEP--VINGSSQHDI--------------GPSGEATVDN--------------PLRL-VGRMVLQQSYICALIAMMVWSITYHSWLTFVLLLWSCVIWMLRTRQRFAAYCSPFILLYGLALCCLQYVWAMDLETELPQHI-----GSMSLHQLGLDRAQYPCLRLGALLLFTLTFWLLLRQSVKDTFSRKKSLTVPLQEVTTGESTGRNES---------ILKVFGGLVMSLYAKYWIYVCGGMFIMVSFAGKLVAYKIVYMLLFLLCMCLYQVYYSLWRRLLKAFWWMVVAYTMVVLIAIYTFQFEDFPGYWGNFTGFTEQQLADMGLETFKLSELFTSIVIPGFFLLACILQLHYFHKPFMKITDLENVSPIHRHE--PEEEELIVDQDDYP----SEADEVIPSKWGLVMDRLMVLSRKFSDTLTHVQSFIWRVLELHIVKIVAFFVVWVALLEPSAMNLVLVVLWSFAMPYGRFRAMASCLSTIWVCVIIVCKMLYQLSVVNPAEYSNNCTAPMVNETSLEPDEVLNSTLYRASVDPASWFGVRKDDTVLGYVKDHLLVLMLLVFEATVYRHQIHHYRQQQRSPPPIPVIFPQATRDTLDQGLLHCIKYMLNYSFYKFGLEICFLMTVNVIGQRMNFLVIIHGCWLVAIMVRRRRANIATIWSKYCLFLVVFMIYQYVLCVGIPPALCIDYPWRWRSTVTIHSALVKWMYLPDFYTVPNSKNLISDFLLLMCASQQWTVFDNEKKEEWMVMGGENRDNPDPMENMLFNPAPNFINCR-SYLDMAKILVFRYMFWFVLSVVFVTGATRISVFGLGYLMACFFFLLFGTKLLTKPSRTRLVMWDCLIIYNVAVIISKNILSILACVFVMEM-QKNFCWVIQLFSLVCTVKGYYDPESVC-NKDCSLPVE--EAGIIWDSICFFFLLLQRRVFLSFYFLHVSADLQASARQASRGFELFRASIIKNMHFHQQAER 1296

HSP 2 Score: 397.512 bits (1020), Expect = 1.247e-110
Identity = 223/592 (37.67%), Postives = 348/592 (58.78%), Query Frame = 2 
Query: 6182 FYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKL-KVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHN-QTYLNLTLSMKKE------NEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR---HN 7921
            F+  + + ++    DVY  MFL + + F+IIIFG+ +FG  + +AD A   +  +++P  F+ M++ QF  +IIDRAL+LRK + GK IFQ+  V  IH W+FF LP +T++ FN     QL YF KCIYF LSAYQ++ GYP RILGNFLT+ FN++NLFLF+G+ +VPFL ELR VMDW+WTDT+++L +WM VED++  IF++KC R +E +YP  +G  ++   KY +GGL++ F     W PL   S + +   V N P++ T ++ +GGY PLF    ++ +++   +  ++++   +   +    ++  +   D+   +I+GSS  VW I+PPS ++L K  L ST  + + +    +R      T E      +     +N  +  L ++        V +  +FP ++ A     ++    L D + + + ++T+S+ +E          WW+I   +A    C      K+S + L + IF+++VS    G L + YGI+G+Y + + V  + +R F+S+IS+ I  EELP  DRIL L  +I+LVRE     LEE+L +KLIFLYRS ETMIKWTR   HN
Sbjct: 1858 FFQNILHAEYRASTDVYALMFLTDVVDFIIIIFGFWAFGKHSAAADIASS-LSEDQVPEAFLVMLLIQFSTMIIDRALYLRKSILGKLIFQVILVFGIHLWMFFILPAVTERMFNHNSVAQLWYFFKCIYFTLSAYQIRCGYPTRILGNFLTKKFNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKRIVKYGMGGLIILFLICIIWFPLLFISLVKSVVGVVNHPVDVTVTVKLGGYEPLFTMSVQQQSIQPFTESRYNQLNNQFSKNAVAMQFITMYSYEDIVTANIEGSSGSVWRISPPSRQELIKELLSSTGDMTLRLDWNFQRDLGKGGTVENTFDKHSISLAPKNPVRADLASLLLGTRKDPVHVPHMFPNYIRAPSGAEAKPVMQLFDGDEEGFQDVTVSLMREASVNTTGAQEWWDIS--IAD---C------KESCNVLPMIIFNDKVSPPSLGFL-AGYGIMGLYVSVVLVIGKFVRGFFSEISHSIMFEELPCADRILKLCMDIFLVRETGELELEEELYSKLIFLYRSPETMIKWTREKNHN 2436

HSP 3 Score: 122.094 bits (305), Expect = 8.881e-27
Identity = 69/150 (46.00%), Postives = 103/150 (68.67%), Query Frame = 2 
Query: 5600 EEYLKEQEXXXXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFN---ETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW 6040
            +E ++ +EF  S++R   L  +L NV   +SE VCYF+++LN++++ ++ SL  P++VFLWAMLSVPRPSK FW+  I YTE+++V+KY+FQF F  +N   E   +   P + P I+G+EK+ NY   DL+QLL +F HR  L+  GLW
Sbjct: 1596 DELIQSREFYSSQNRLLKLLFALYNVLAAHSELVCYFIIVLNNLVTASVISLVLPVLVFLWAMLSVPRPSKRFWMTAIIYTEVMVVVKYLFQFGFFPWNTEYELKLNEDKPFFPPRILGLEKTDNYIRYDLLQLLVLFFHRSLLQRYGLW 1745
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Zebrafish
Match: piezo2a.2 (piezo-type mechanosensitive ion channel component 2a, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-131119-76])

HSP 1 Score: 449.899 bits (1156), Expect = 1.227e-126
Identity = 231/588 (39.29%), Postives = 360/588 (61.22%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERR-SSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKK-----ENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            +R+F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P  F+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T+++F+     QL YFVKCIYF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IFVLKCWR SE  YP  RG  ++   KY +GG+++       W PL   S + +   V N P++ + +I++GG+ P+F   +++N LK L +  F      Y        +L ++ A DVT   ++GSS+ +WTI+PPS + L   L   +   + M    +R  S  +K+   M +H     LD   ++ L+  +   +++ V+ I+ +FP F+ A   + ++    L + +  Y ++ L +++     E+   WW + E+ + +         +Q  + L +++FS++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR
Sbjct: 2045 IRQFFYSLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPEAFLVMVLIQFGTMVVDRALYLRKTVMGKVIFQVILVFGIHFWMFFILPGVTERRFSQNTVAQLWYFVKCIYFGLSAYQIRCGYPTRVLGNFLTKSYNYLNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFVLKCWRESEKRYPQPRGQKKKKVVKYGMGGMIVMLLICIVWFPLLFMSLVKSVAGVVNKPLDVSVTITLGGFQPIFTMSAQQNQLKELTESDFKNFINSYNYVPSAMQFLEAYRAEDVTVAELEGSSNSLWTISPPSRKNLMDVLSKEDQFPVTMTWSIQRNLSLGAKSEFAMDKHVT--YLDIKTRQELIALLNGTRNTPVL-IEQVFPCFIRAPSDSNAKPIEQLYE-DGVYKSIQLDLERSANSSEDLQEWWIVDELRSAQK--------QQREAGLQLYVFSDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPCVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTR 2618

HSP 2 Score: 259.225 bits (661), Expect = 2.518e-68
Identity = 175/615 (28.46%), Postives = 311/615 (50.57%), Query Frame = 2 
Query: 2621 DVNSAFQIIIEKLKQFF-------EVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSL---YTTNFNKSMDQ-------IDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPN-ATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQR-KICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTI------DKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGDKY 4378
            ++ S + +++E+L   F       + +   +W   E H  KIV   I+   + E +  N V ++      PF +   +  +    W  + ++ KM+YQL +++   ++ NCS+   YT      M +       +D A WIGL K +   +++     +++    + V  Y  + FY+  N  T P T  IF   T Q +DD ++N  K+ IN+ FYK GLE  F++ V V   R+D +++++   L+  +  +R K  + +W  Y  FL  LL  +Y +C+G+PP  C  YP     +S+  N+ +WL+ P +   P++  ++ DF   +  +LQ RVF  E  ++      G N  I C +L            DF+  + SY+D LK  +F + +W  L I+F TG   I++FC+GY++  F +L  G  ++L+   +++  W+ +I YN FVI  K  L +  C Y+  +++   CW+I LF + C     + +     N+    P  S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E+  +D +K ++D+I  RQ +  + +     L   SG+++
Sbjct:  781 ELKSKWHLVVERLTVLFLKFLDCIQKLQLFIWWILELHIIKIVSSYIIWVSVKEVSLFNYVFVVSWAFALPFCQFRPLASSVCTVWTCIIIVCKMLYQLTSISPAAYARNCSMPDNYTEAQRMDMAKSLLYIGPVDPANWIGLRKFSPLLEYLRN-NLLMLALLAFEVTIYRHQDFYRMKNNITPPVTRTIFHNITRQHLDDGIVNCAKYFINYFFYKFGLETCFLLAVNVIGQRMDFFAMLHAFGLIAVMYQRRRKAIAHVWSKYCCFLACLLSFQYLMCIGIPPAACTDYPWRRSSSSMDSNVIKWLYFPDFHTKPNSLFLLYDFMLLLCASLQGRVFE-EECVSPVQLLAGDNVEI-CRDLDAATFSQHNPVPDFIHCR-SYLDMLKVMVFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLIFGGELLLKPIKSILHYWDFLIAYNVFVITMKNILSIAACGYIKALVANH-CWLIQLFSLAC-TIKGYSKPEQQANKQCELP--SDEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIRSSQLLASRGAELFQATIVKAVKARIEEEKKSMDLLKRQMDRIKSRQQKFKRGKERMLSLAQESGERH 1387

HSP 3 Score: 223.787 bits (569), Expect = 1.324e-57
Identity = 162/577 (28.08%), Postives = 281/577 (48.70%), Query Frame = 2 
Query:  851 VVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRG--EVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRS----------------YKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAV--LDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFN-LTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN 2518
            V+ G  G++ PS+ +SVY F FLG+CT+W+         F+ + + + ++SA H+  LYL Q +F Q  +P  N  + L G+  +V T C      +VN     W  +++P +++ +YY  AT  R W ++  ++V    +                Y  D +    + ++ H  E  L+  +EA N    L+ +S     ++ ++    +    +     T          D+Q     V  +D   ++   L         ++ +    ++ S++   IAMMAWS+TY SW++F+ L+ +C LWM+ D RK  +  SP +VFY  +LII+QYI+ F  L  +P                 F K  +P   L      L+ FWL LR F+T+     +   + L+D   D       +   G+ + M  + + S L  +  KYWI +C     FVS +  +V+++I+YM++ ++ +  +   Y  WR  +  FW  V+VY+++VL+ +YT+QF     +W N TG+S E L+D+GL+ +    LF  +  P  FL+V I+ + YFH+ FL+L+ + 
Sbjct:  129 VLLGLTGMMLPSLTSSVYFFTFLGLCTWWSFCRSFDPLLFSCLCVLMAIFSAGHLVFLYLYQFQFFQEAVPPGNTYASLFGISPVVQTDCSHTWMFKVN-PALEWHHFVNPIMLLVLYYTLATLIRLWLQESEDTVRDAEAEGKDDAASPENTDINVYTADQRRQLWRMAHYHTDERNLLTAQEAYNSPEVLIVTSNGASLDFTSVSHEKRPKCVERNLYSTPHYKADQPESDTQSLDCGVYRIDSAYVELSELPVAVVRVNSVVKVFRFIMKQSYICALIAMMAWSITYVSWLTFVFLIWSCTLWMVRDRRKYSMVTSPFMVFYGNLLIILQYIWSFECLQPVPGL---------------FLKKEVPFRELGSKTLCLLSFWLLLRQFLTERREKHTDDPQ-LSDVTVDGHKLGLQDEAAGHREMM--EVLGSSLMAMLNKYWIYICGGMFFFVSFEGRIVMYKIIYMMMFLFCVALYQLHYERWRWMLKYFWMSVVVYTMLVLILVYTFQFESSINVWSNMTGMSREKLEDLGLEKFSVPALFTRIFIPTWFLLVCILHLHYFHERFLELTDIK 686

HSP 4 Score: 119.013 bits (297), Expect = 7.914e-26
Identity = 73/168 (43.45%), Postives = 102/168 (60.71%), Query Frame = 2 
Query: 5654 LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTN-DRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWS 6154
            L  SL NV + +S+ VCY ++ILNHM+S ++ +L  P+++FLWAMLSVPRPSK FW+  I YTE+ IVIKY FQF F  FN++   D+  P   P IIG+EK + Y   DL+QLL +F HR  LK  GLW +     +   +      G  +    + E SP  + ++
Sbjct: 1796 LCYSLYNVLVSHSQMVCYLVIILNHMISASVATLVLPVLIFLWAMLSVPRPSKRFWMTAIVYTEVTIVIKYFFQFGFFPFNQSIEVDKSKPFHPPNIIGVEKKEGYVHYDLVQLLALFFHRSILKCYGLWDEE----EPRSVSPHTHSGAEEKAECFSEKSPVEDTYT 1959
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Zebrafish
Match: CU179656.1 (pep chromosome:GRCz11:2:54086436:54270366:1 gene:ENSDARG00000107086.2 transcript:ENSDART00000174581.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CU179656.1)

HSP 1 Score: 385.571 bits (989), Expect = 1.333e-109
Identity = 315/1229 (25.63%), Postives = 563/1229 (45.81%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGN-EFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPL-LLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNE---ILNDSKFDQSSNADSEAYFGN----------VDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHK----------------------------PFLKLS---------------------------SMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLK-------QFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNA-TKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQR-KICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTI------DKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCI----NPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLIN-RKMMAS 4237
             VVVT   G  G+  PS+ ++VY F FLG+CT+W+         F+ + + + ++SA H+ +LY+ Q +F+Q  +   +  + + G+  ++ T C +  ++   +  +W  +++P +I+ +YY  AT  R W +   + +  V  Y  D+         E   ++ ++   +   +   L+ +S     +Y +   P +  +   + DI +    +  +  +  G      +    +           P  L+ +    ++ S++   IAMMAWS+TY SW++F+ L+ +C LWM+ D RK  +  SP +V Y   L+++QYI+ F   +        SG         F K  +P   L+  +   + FWL LR     TL+   ++ E    L+D K D+    D      N           +N + + +   +  +  KYWI VC     FVS +  +  ++I+YM++L+  +  +   Y +WR+ +  FW  V+VY+++VL+ IYT QF      W   TGL +++L+DIGL+ +  S+LF  +  P  FL+V I+ + YFH                             PF +L+                           S+N  L  D       +D+L+I ++    S V   + ++ + + +++++L        ++F  +   VW   E H  KIV   I+   + E +  N V +I      P+ +   +  +    W  + ++ K+ YQLKT+N  N+S++C +                                          + V  Y  ++F++  N  + P +  IF + T Q +D+ +I   K+ IN+ FYK GLE+ F++ + V   R+D YS+V+ + L + +  +R K  ++IW  Y  FL  ++  +Y IC+G+PP  C  YP     +S+  N+ +WL+LP +  PPS+  +  DF   +  +LQ +VF  EN   V    G      +C +L            DF+  + SY+D LK  +F + +W  L I+F TG   I++FC+GY++  F +L  G  ++L+    ++  W+ +I YN FVI  K    ++ C Y++ ++ K  CW+I L  + C      P + D  +              ++G+ WD  CF F++LQR++FM+  F HV+ D+      ASR  +  + R +MA 
Sbjct:  203 QVVVTIMLGMTGVTLPSLSSAVYFFVFLGLCTWWSLCKTFDKLLFSCLCVLMAIFSAGHLIVLYINQFQFLQEAISPTDGYTSVFGISSIIYTDCSSTWKLAVRSGLKWHHFVNPIMILVLYYTLATLIRLWLQ---DPMMMVSLYTIDLAFW------EILFQISILKTHQKTEERNVLVVTSNGTSFDYVSAV-PIE--NGPVSLDIYSTPQYKVDQSVEYDGELEEEEEKTDEEEEAEEEEQGGPPAALVKVFKFIMKQSYICALIAMMAWSITYVSWLTFVFLIWSCTLWMVRDRRKYAMLTSPFMVAYGNFLLVLQYIWCFEKLK------PVSGF--------FVKMEVPFTELSTKVLCQLSFWLLLR----QTLMERQERKEEEAALSDIKVDEQKKGDLFIRVYNRLEEKSEEEVDENDLMQVLGKLVMALLVKYWIYVCGGMFFFVSFEGDMATYKIIYMMMLLSCVALYQVHYEYWRRILKYFWMSVVVYTMLVLILIYTSQFEDGIPTWTRMTGLDKDVLKDIGLEKFSLSNLFTRIFIPTSFLLVCILHLHYFHDHFLELTDLKAVVSKQESTIYSVLSNALFPFSRLAHPDGSLADLTIVSSSPEPLLKDEKEKESLNEVLVVDCVGEEKKKDSLSIYSAQMIESLVVC-VSEMKNKWHLVVDRLTVLFLKFLEYFHKLKLFVWWLLEMHIIKIVATYIILLSVKEVSLLNFVFLISWAFALPYKQFRVLSSSVCTVWTCVIIVCKLFYQLKTINPANYSSDCIMNNLLMLAL--------------------------------LAFEVTIYRHQEFFRLRNKLSPPPSRTIFHDITRQHLDNGIIECAKYFINYFFYKFGLEVCFLLAINVMGQRMDFYSMVHGLALAVVMFRRRRKAIAEIWPKYCCFLACMITFQYFICIGIPPAACADYPWRFPNSSMTSNVIKWLYLPDFHTPPSSMFLGYDFMLLLCASLQRQVFDEENKAAVRLMAGDNVE--ICRDLDAASFSVHNPVPDFIHCR-SYLDMLKVIMFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGQLLLKPIKEILRYWDFLIAYNVFVITMKNVFAILACGYINSLV-KNSCWLIQLLSLACTIKDYQPKTVDCEL-----------PKDEAGIIWDSICFTFLLLQRRVFMSYYFLHVIADIRAGQILASRAYHFSSPRYLMAE 1353
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Xenopus
Match: PIEZO2 (piezo-type mechanosensitive ion channel component 2 [Source:NCBI gene;Acc:100492729])

HSP 1 Score: 540.421 bits (1391), Expect = 1.310e-156
Identity = 306/797 (38.39%), Postives = 460/797 (57.72%), Query Frame = 2 
Query: 5654 LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVD-PLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWR--DHTEFAQDLEIVDKE-------QDGRNKIKSSY-------------EESSPTSNKWSCNP--------------IY-KMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEA----RWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            L  +L N  +  SE VCYF++ILNHM+S ++ +L  P+++FLWAMLSVPRPSK FW+  I YTE+ IVIKY FQF F  +N+  +   D P + P I+GIEK + Y   DL+QLL +F HR  LK +GLW   D TE A D +  D E       +D    +KS               EE +    K + +               IY  +R+F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P  F+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+     QL YFVKCIYF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++   KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   +++N L+ L  + F  +   YK  +P   +L S+   D+T   ++G+S+ +WTI+PP                           S +   E++++  +   +     ++L    E     Y + +           +R L++       +NQ ++N+++ ++KEN +     WW + +        S+++  K+    L +++FS++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR
Sbjct: 1246 LIYALYNTLVARSEMVCYFVIILNHMISASMITLVLPILIFLWAMLSVPRPSKRFWMTAIVYTEVTIVIKYFFQFGFFPWNKNVDYTKDKPYFPPNIMGIEKKEGYVHYDLVQLLALFFHRSILKCHGLWDEDDVTEKATDKDDTDGEISEASGRRDSVGSLKSVNLAASVESVHVHFPEEKTAIRRKSTSSGSQISRRSSYSSILQIYVPIRQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPEAFLVMVLIQFGTMVVDRALYLRKTVMGKVIFQVILVFGIHFWMFFILPGVTERKFSQNTVAQLWYFVKCIYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVTNKPLDVSITITLGGYQPIFTMSAQQNQLQGLNDNEFKHLHNIYKGNTPAMQFLESYMQEDITIAGLEGNSNSLWTISPP---------------------------SRTMMIERLIQEPDFTAVISWSIRSLGAKAEVTGEKYTISLAG-------QTRRELADMM-----NNQEFVNISVLLRKENTSEGVREWWVVNQ--------SHKEFIKK--DGLELWVFSDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTR 1991

HSP 2 Score: 363.999 bits (933), Expect = 1.925e-100
Identity = 266/887 (29.99%), Postives = 431/887 (48.59%), Query Frame = 2 
Query: 1637 MMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLK-------QFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQ------------IDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRF-CWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASR 4201
            + AWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V Y  +L+ +QYI+   L   ELPE              +G  +   P   L   I F V FWL LR  +T+    A KQ E+      D              +N I K +   +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WR+ +  FW  V+VY+++VL+ IYTYQF  FP LW N TGL +E L D+GL+T+  +DLF  +  P  FL+V I+ + YFH  FL+L+ +         +     D+  I   S+    +     +  + + ++I++L        ++F      VW   E H  KIV   I+   I E +  N V  I      P+ +   +  +    W  + ++ KM+YQL +++   +S+NC +   N   + +Q            +D + W+GL+K      ++     +L + A    +  HQ  +    N T P T  IF + T   +DD LIN  K+ +N+ FYK GLE  F+++V V   R+D +++V+ + L  +    +RK  ++ W  Y  FL  ++  +Y IC+G+PP  C+ YP      +   N+ +WL+ P +   PS   ++ DF   +  +LQ  VF  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  +F + +W  L I+F TG   I++FC+GY++  F +L  G +++L+    ++  W+ +I YN FVI  K  L           +S  F CW+I  F + C       +              S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASR
Sbjct:  231 LQAWSITYHSWLTFVLLIWSCALWMVRNRRKYAMLSSPFMVMYGNLLLTLQYIWSIALQSDELPEV-------------MGLLERKKPE-ELVSKIIFTVTFWLLLRQHLTEQ--KALKQKELALSEIKD--------------ENDIMKVLGKLVQAMFVKYWIYVCGGMFFFVSFEGKIVMYKIIYMMLFLFCVALYQVHYEWWRRILKYFWMSVVVYTMLVLVFIYTYQFKSFPGLWMNMTGLDKEKLADLGLETFNLTDLFTRIFIPTSFLLVCILHLHYFHDRFLQLTDLKAVTRMQQIQ-DSVRDSAKIQHFSAGFGQIHGL--ESRNKWHLVIDRLTVLFLKFLEYFHKFQVFVWWLLELHMIKIVSSYIIWLTIKEVSLLNYVFFIAWAFALPYSQFRPLASSVCTVWTCVIIICKMLYQLASIDPATFSSNCLMPQLNETTARNQTELNSSVLYNSSVDPSNWVGLKKSTPLLAYLRNNLLMLAMLAFEVTIYRHQEYYRLRNNLTTPATKTIFHDITRLHLDDGLINSAKYFVNYFFYKFGLETCFLLSVNVIGQRMDFFAMVHALWLFGVLYRRRRKAIAETWHRYCCFLACIMAFQYFICIGIPPAACKDYPWRQPGANFNSNIIKWLYFPDFIVRPSPLFLVYDFLLLLCASLQREVFEEENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIYCR-SYLDMGKVIMFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIRIILRYWDWLIAYNVFVITMKNVLS----------VSVLFHCWLIQAFSLSCTV-----KGYFIPQNTPDCQLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKSSQILASR 1067

HSP 3 Score: 75.0998 bits (183), Expect = 2.090e-12
Identity = 39/120 (32.50%), Postives = 69/120 (57.50%), Query Frame = 2 
Query:  851 VVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHR---WIDYLSPCIIMYVYY 1201
            ++ G  G++ PS+ ++VY F FLG+CT+W+C        F+ + + + ++SA H+  LYL Q++F    +P N+F +RL G+  LV T C       F+ +    W  Y +P +++ +YY
Sbjct:   53 ILLGLTGMMLPSLTSAVYFFVFLGLCTWWSCCRVFDPLIFSCLCVLMAIFSAGHLIGLYLYQLQFFHEIIPPNDFYARLFGVTSLVQTDCCNTWR--FFANNSLPWNQYTNPVMLLVLYY 170
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Xenopus
Match: PIEZO2 (piezo-type mechanosensitive ion channel component 2 [Source:NCBI gene;Acc:100492729])

HSP 1 Score: 541.191 bits (1393), Expect = 1.853e-156
Identity = 312/827 (37.73%), Postives = 471/827 (56.95%), Query Frame = 2 
Query: 5567 GSHSFVNSKNQEEYLKEQEXXXXXXXXXL-LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVD-PLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWR--DHTEFAQDLEIVDKE-------QDGRNKIKSSY-------------EESSPTSNKWSCN--------------PIY-KMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEA----RWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
             S   +N    +E L++ E   +     L L  +L N  +  SE VCYF++ILNHM+S ++ +L  P+++FLWAMLSVPRPSK FW+  I YTE+ IVIKY FQF F  +N+  +   D P + P I+GIEK + Y   DL+QLL +F HR  LK +GLW   D TE A D +  D E       +D    +KS               EE +    K + +               IY  +R+F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P  F+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+     QL YFVKCIYF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++   KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   +++N L+ L  + F  +   YK  +P   +L S+   D+T   ++G+S+ +WTI+PP                           S +   E++++  +   +     ++L    E     Y + +           +R L++       +NQ ++N+++ ++KEN +     WW + +        S+++  K+    L +++FS++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR
Sbjct: 1290 ASELLLNKMFYDEELEDSEKFYTTQPRPLQLIYALYNTLVARSEMVCYFVIILNHMISASMITLVLPILIFLWAMLSVPRPSKRFWMTAIVYTEVTIVIKYFFQFGFFPWNKNVDYTKDKPYFPPNIMGIEKKEGYVHYDLVQLLALFFHRSILKCHGLWDEDDVTEKATDKDDTDGEISEASGRRDSVGSLKSVNLAASVESVHVHFPEEKTAIRRKSTSSGSQISRRSSYSSILQIYVPIRQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPEAFLVMVLIQFGTMVVDRALYLRKTVMGKVIFQVILVFGIHFWMFFILPGVTERKFSQNTVAQLWYFVKCIYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVTNKPLDVSITITLGGYQPIFTMSAQQNQLQGLNDNEFKHLHNIYKGNTPAMQFLESYMQEDITIAGLEGNSNSLWTISPP---------------------------SRTMMIERLIQEPDFTAVISWSIRSLGAKAEVTGEKYTISLAG-------QTRRELADMM-----NNQEFVNISVLLRKENTSEGVREWWVVNQ--------SHKEFIKK--DGLELWVFSDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTR 2065

HSP 2 Score: 371.318 bits (952), Expect = 1.133e-102
Identity = 267/880 (30.34%), Postives = 431/880 (48.98%), Query Frame = 2 
Query: 1637 MMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQ------------IDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRF-CWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASR 4201
            + AWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V Y  +L+ +QYI+   L   ELPE              +G  +   P   L   I F V FWL LR  +T+    A KQ E+        S + + E      +N I K +   +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WR+ +  FW  V+VY+++VL+ IYTYQF  FP LW N TGL +E L D+GL+T+  +DLF  +  P  FL+V I+ + YFH  FL+L+ +        +++ P +        S+  +     I+ +   F     K  ++F      VW   E H  KIV   I+   I E +  N V  I      P+ +   +  +    W  + ++ KM+YQL +++   +S+NC +   N   + +Q            +D + W+GL+K      ++     +L + A    +  HQ  +    N T P T  IF + T   +DD LIN  K+ +N+ FYK GLE  F+++V V   R+D +++V+ + L  +    +RK  ++ W  Y  FL  ++  +Y IC+G+PP  C+ YP      +   N+ +WL+ P +   PS   ++ DF   +  +LQ  VF  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  +F + +W  L I+F TG   I++FC+GY++  F +L  G +++L+    ++  W+ +I YN FVI  K  L           +S  F CW+I  F + C       +              S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASR
Sbjct:  245 LQAWSITYHSWLTFVLLIWSCALWMVRNRRKYAMLSSPFMVMYGNLLLTLQYIWSIALQSDELPEV-------------MGLLERKKPE-ELVSKIIFTVTFWLLLRQHLTEQ--KALKQKELALSEIKVGSEDKEVED-----ENDIMKVLGKLVQAMFVKYWIYVCGGMFFFVSFEGKIVMYKIIYMMLFLFCVALYQVHYEWWRRILKYFWMSVVVYTMLVLVFIYTYQFKSFPGLWMNMTGLDKEKLADLGLETFNLTDLFTRIFIPTSFLLVCILHLHYFHDRFLQLTDLKAV--TSKQDIPPLDHQFKTKYRSAPQNKWHLVIDRLTVLFL----KFLEYFHKFQVFVWWLLELHMIKIVSSYIIWLTIKEVSLLNYVFFIAWAFALPYSQFRPLASSVCTVWTCVIIICKMLYQLASIDPATFSSNCLMPQLNETTARNQTELNSSVLYNSSVDPSNWVGLKKSTPLLAYLRNNLLMLAMLAFEVTIYRHQEYYRLRNNLTTPATKTIFHDITRLHLDDGLINSAKYFVNYFFYKFGLETCFLLSVNVIGQRMDFFAMVHALWLFGVLYRRRRKAIAETWHRYCCFLACIMAFQYFICIGIPPAACKDYPWRQPGANFNSNIIKWLYFPDFIVRPSPLFLVYDFLLLLCASLQREVFEEENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIYCR-SYLDMGKVIMFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIRIILRYWDWLIAYNVFVITMKNVLS----------VSVLFHCWLIQAFSLSCTV-----KGYFIPQNTPDCQLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKSSQILASR 1080

HSP 3 Score: 86.6557 bits (213), Expect = 7.685e-16
Identity = 49/154 (31.82%), Postives = 84/154 (54.55%), Query Frame = 2 
Query:  851 VVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHR---WIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQ 1303
            ++ G  G++ PS+ ++VY F FLG+CT+W+C        F+ + + + ++SA H+  LYL Q++F    +P N+F +RL G+  LV T C       F+ +    W  Y +P +++ +YY  AT  R W ++   SV   RS    + +S + Q
Sbjct:   53 ILLGLTGMMLPSLTSAVYFFVFLGLCTWWSCCRVFDPLIFSCLCVLMAIFSAGHLIGLYLYQLQFFHEIIPPNDFYARLFGVTSLVQTDCCNTWR--FFANNSLPWNQYTNPVMLLVLYYTLATLIRLWLQEPIVSVWLFRSRNIQLVLSLMAQ 204
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Xenopus
Match: PIEZO2 (piezo-type mechanosensitive ion channel component 2 [Source:NCBI gene;Acc:100492729])

HSP 1 Score: 530.406 bits (1365), Expect = 1.351e-153
Identity = 303/768 (39.45%), Postives = 451/768 (58.72%), Query Frame = 2 
Query: 5654 LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVD-PLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWR--DHTEFAQDLEIVDKEQDGRNKIKSSYEESS-----PTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTN-TKQLDENDKKNLLKAIEAN--QSSYVVQIDAIFPRFLTAYKRTLSEAT--ALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            L  +L N  +  SE VCYF++ILNHM+S ++ +L  P+++FLWAMLSVPRPSK FW+  I YTE+ IVIKY FQF F  +N+  +   D P + P I+GIEK + Y   DL+QLL +F HR  LK +GLW   D TE A D +  D E    +  + S+         P+       PI   R+F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P  F+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+     QL YFVKCIYF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++   KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   +++N L+ L  + F  +   YK  +P   +L S+   D+T   ++G+S+ +WTI+PP                           S +   E++++  + T  +  + ++ ++ ++  N   S     I  I+P  L A     ++     LL+  N +          E    WW + +        S+++  K+    L +++FS++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR
Sbjct: 1214 LIYALYNTLVARSEMVCYFVIILNHMISASMITLVLPILIFLWAMLSVPRPSKRFWMTAIVYTEVTIVIKYFFQFGFFPWNKNVDYTKDKPYFPPNIMGIEKKEGYVHYDLVQLLALFFHRSILKCHGLWDEDDVTEKATDKDDTDGEISEASGRRDSFFILYILCFFPSRILQIYVPI---RQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPEAFLVMVLIQFGTMVVDRALYLRKTVMGKVIFQVILVFGIHFWMFFILPGVTERKFSQNTVAQLWYFVKCIYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVTNKPLDVSITITLGGYQPIFTMSAQQNQLQGLNDNEFKHLHNIYKGNTPAMQFLESYMQEDITIAGLEGNSNSLWTISPP---------------------------SRTMMIERLIQEPDFTAVISWSIRRYIISSLFYNLPNSFSYRPIFHIYPLCLKAPSDVTAKPILHVLLRKENTS----------EGVREWWVVNQ--------SHKEFIKK--DGLELWVFSDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTR 1929

HSP 2 Score: 389.037 bits (998), Expect = 2.149e-108
Identity = 278/891 (31.20%), Postives = 444/891 (49.83%), Query Frame = 2 
Query: 1604 IRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVD-NMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQ------------IDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASR 4201
            ++ S++   I+MMAWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V Y  +L+ +QYI+   L   ELPE     S   +  + I           L   I F V FWL LR  +T+    A KQ E+           A SE   G  D N I K +   +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WR+ +  FW  V+VY+++VL+ IYTYQF  FP LW N TGL +E L D+GL+T+  +DLF  +  P  FL+V I+ + YFH  FL+L+ + + +  DS+E  P   N                   V     ++  K  ++F      VW   E H  KIV   I+   I E +  N V  I      P+ +   +  +    W  + ++ KM+YQL +++   +S+NC +   N   + +Q            +D + W+GL+K      ++     +L + A    +  HQ  +    N T P T  IF + T   +DD LIN  K+ +N+ FYK GLE  F+++V V   R+D +++V+ + L  +    +RK  ++ W  Y  FL  ++  +Y IC+G+PP  C+ YP      +   N+ +WL+ P +   PS   ++ DF   +  +LQ  VF  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  +F + +W  L I+F TG   I++FC+GY++  F +L  G +++L+    ++  W+ +I YN FVI  K  L +  C Y++++I K  CW+I  F + C       +              S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASR
Sbjct:  162 MKQSYICALISMMAWSITYHSWLTFVLLIWSCALWMVRNRRKYAMLSSPFMVMYGNLLLTLQYIWSIALQSDELPEVMEFESNYKMYGNYI----------LLVFQIIFTVTFWLLLRQHLTEQ--KALKQKEL-----------ALSEIKVGMEDENDIMKVLGKLVQAMFVKYWIYVCGGMFFFVSFEGKIVMYKIIYMMLFLFCVALYQVHYEWWRRILKYFWMSVVVYTMLVLVFIYTYQFKSFPGLWMNMTGLDKEKLADLGLETFNLTDLFTRIFIPTSFLLVCILHLHYFHDRFLQLTDL-KAVTRDSKE--PESRNK---------------WHLVIDRLTVLFLKFLEYFHKFQVFVWWLLELHMIKIVSSYIIWLTIKEVSLLNYVFFIAWAFALPYSQFRPLASSVCTVWTCVIIICKMLYQLASIDPATFSSNCLMPQLNETTARNQTELNSSVLYNSSVDPSNWVGLKKSTPLLAYLRNNLLMLAMLAFEVTIYRHQEYYRLRNNLTTPATKTIFHDITRLHLDDGLINSAKYFVNYFFYKFGLETCFLLSVNVIGQRMDFFAMVHALWLFGVLYRRRRKAIAETWHRYCCFLACIMAFQYFICIGIPPAACKDYPWRQPGANFNSNIIKWLYFPDFIVRPSPLFLVYDFLLLLCASLQREVFEEENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIYCR-SYLDMGKVIMFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIRIILRYWDWLIAYNVFVITMKNVLSIGACGYIEYLI-KDSCWLIQAFSLSCTV-----KGYFIPQNTPDCQLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKSSQILASR 1003

HSP 3 Score: 58.5362 bits (140), Expect = 1.991e-7
Identity = 26/75 (34.67%), Postives = 47/75 (62.67%), Query Frame = 2 
Query:  851 VVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNF 1075
            ++ G  G++ PS+ ++VY F FLG+CT+W+C        F+ + + + ++SA H+  LYL Q++F    +P N+F
Sbjct:   53 ILLGLTGMMLPSLTSAVYFFVFLGLCTWWSCCRVFDPLIFSCLCVLMAIFSAGHLIGLYLYQLQFFHEIIPPNDF 127
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Xenopus
Match: chordc1 (cysteine and histidine rich domain containing 1 [Source:Xenbase;Acc:XB-GENE-962949])

HSP 1 Score: 499.59 bits (1285), Expect = 8.771e-143
Identity = 295/803 (36.74%), Postives = 458/803 (57.04%), Query Frame = 2 
Query: 5654 LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW------------------RDHTEFAQDLEIVDK-----EQDGRNKIKSSYEESSPTSNKWSC--------NPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTES-----LKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLK-DHNQTYLNLTLSMKKENEA---------RWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWT 7912
            L ++L N    +SE +CYF++ILN+M+S +L SL  P+++FLW MLS+ +PSK FW+  I +TE+++VIKY+FQF F  +N  T    +   P + P ++G+EKS +Y   DLIQLL +F HR  L + GLW                  +   + +QDLE          Q  R + + S +E    SN W+C        N    ++ F+  + + K     DVY FMFL + + F+II+FG+ +FG  + +AD A   +  +++P  F+ M++ QF  ++IDRAL+LRK V GK IFQ+  V+ IH W+FF LP +T++ FN     QL YFVKCIYFALSAYQ++ GYP RILGNFLT+ +N++NLFLF+G+ +VPFL ELR VMDW+WTDT+++L +WM VED++  IF++KC R +E +YP  +G  ++   KY +GGL++ F     W PL   S + +   V N PI+ T +  +GGY PLF   +++ +++      ++ +   ++       ++  +   D+    I+GSS  VW I+PPS E+++ +L++  S        + Q    +  +   T+EK  +       +  +  +LL+ +        V I  +FP+++ A     +     L+ D  ++YL++ + + +   A          WW I          + +    +  + L + IF+++VS    G L + YGI+G+Y + + V  + +R F+S+IS+ I  EELP VDRIL L  +IY+VRE     LEE+L AKLIFLYRS ETMIKWT
Sbjct: 1368 LLLALYNFVAAHSELLCYFIIILNNMVSASLISLFLPILIFLWGMLSIHKPSKRFWMTAIIFTEVMVVIKYLFQFGFFPWNNYTILVRNEGKPFFPPRVLGLEKSDSYIKYDLIQLLMLFFHRSLLMSYGLWDRKDLDLEERTPGKDKGSKTEIQASQDLEPAGGSSSSLRQRKRKESQGSVQERGAESN-WTCAVQFTSLRNIYQPVKAFFHDILHTKNRAATDVYAFMFLADVVDFVIIVFGFWAFGKHSAAADIASS-LSDDQVPEAFLVMVLIQFSTMVIDRALYLRKTVLGKLIFQVILVIGIHVWMFFILPAVTERMFNQNTVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIIVFLICIIWFPLLFMSLVRSVVGVVNHPIDVTVTFKLGGYEPLFTMSAQQQSIQPFTPQQYEALTYEFERQPTAMQFITLYSYEDIVTARIEGSSGSVWGISPPSREQMRKELQNGSSDITLRFTWDFQRDLAKGGTVEHTSEKHTKDLEPGSQERMELADLLQGVRDTP----VSIQHLFPKYIRAPNGPEANPVKQLQPDEEESYLDVEVQLNRMRVAEGNSTSSFVEWWVI----------TLKDCEGEDCNILPMVIFNDKVSPPSLGFL-AGYGIMGLYVSIVLVIGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIYVVRERGELELEEELYAKLIFLYRSPETMIKWT 2153

HSP 2 Score: 388.267 bits (996), Expect = 7.888e-108
Identity = 272/897 (30.32%), Postives = 442/897 (49.28%), Query Frame = 2 
Query: 1622 FTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNL-TELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLN----IXXXXXXXXNVSAFIED------VNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSM------------DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKI-CSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-----LTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIEN--------SLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASR 4201
            F+FI  +   +TY SW++F+LLL AC +WM+ + R+  +  SP I+ Y   L  +QY++  +L  ELP    T  G  + LS++G  +   P   +  ++ + + FWL L  F+T+  L   K    L +    + +              + K+    +     KYWI VC    + VS    +VV++IVYMLL +  L+ F   YS WRK +  FWW V+ Y+++VL+ IYT+QF +FP  WKN T L++E L DIGL+ +  S+LF  +L P  FL+  I+Q+ YFH+PF+ ++++       +   G F  +       +         SA   D      V     ++  K  +    +   +WR  E H  K+V    V   + E +  N + ++L     PF +   +       W S+ ++ KM+YQL  VN   +S+NC+    N N S+            + ID A W G+ K      +I     +L++     +V  HQ  + K     KP    +FP+   + +D  L +  K+ IN++FYK GLE+S     I+ C R++   + +   L++ L  ++++  +K+W  Y +FL   L  +Y IC+G+PP LC  YP        +   L +WL+LP +   P +  +++DF   + VA Q++VFI E            V  Y   ++RP   N +P  I+        SY+D +K A+F + +W  L +VF TG   I++F LGY++  F  L  G  ++ +     +  W+ +I YN  VILSK  L L+ C ++  M    FCW+I LF + C     ++   +  +R    P    ++G+ WD  CFLF++LQR++F++  F HVVLDL   +   SR
Sbjct:  237 FSFILTITCGITYHSWLTFVLLLWACLIWMVRNRRQFAMLCSPFILMYGVTLCSLQYVWSMDLREELP----TQLG-FMKLSQLGLVRAPYPCLNMGALLLYTLTFWLLLHQFVTEKFLKRKKFMSPLLEVTVAEKN--------------LLKRFGEQVKSFYAKYWIYVCGGMFIVVSFAGRLVVYKIVYMLLFLLCLVLFQVYYSLWRKLLTFFWWLVVAYTMLVLITIYTFQFEEFPEYWKNLTNLTDEQLGDIGLERFSVSELFTSILIPGFFLLACILQLHYFHRPFMHMTNL-----AHASSQGSFHSHERYAHDAAADEEEDEEESAHGADLSKWDLVTQRLSVLSFKFSELLHRLQVFLWRLLELHVLKLVALYSVWVALQEVSVMNFLFVVLWAFAMPFSRFQHMASCLCTIWTSIIIVCKMLYQLTVVNPLEYSSNCTQPLLN-NTSLLEDEILNSTLYREPIDPANWFGIRKGYPNLGYIQNHLQILLLLVFEAIVYRHQEFYRKQYQLEKPHIQAVFPDVYREHLDQGLFSCIKYFINYSFYKFGLEVSSQECDIL-CFRMNFMVIFHGCWLIVILTRRQRVNIAKLWPKYCVFLIFFLLWQYMICLGIPPVLCIDYPWRWDTFVPVNSALIKWLYLPDFYTTPKSVNLISDFVLLIGVAQQWKVFINEKKEEWYTMAGENVEEYEAPKDRP---NPVPNFIN------CQSYLDMVKVAVFRYLFWFVLTVVFITGATRISVFGLGYLMSCFYLLLSGTTLLQKPMKAKLVLWDCLILYNITVILSKNMLSLLSCVFVQQM-QTNFCWVIQLFSLVCTVKGYYNPQDMDKDRDCSLPVE--EAGIIWDSICFLFLLLQRRVFLSCYFRHVVLDLRASSLQTSR 1095
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Xenopus
Match: chordc1 (cysteine and histidine rich domain containing 1 [Source:Xenbase;Acc:XB-GENE-962949])

HSP 1 Score: 499.975 bits (1286), Expect = 9.703e-143
Identity = 295/803 (36.74%), Postives = 458/803 (57.04%), Query Frame = 2 
Query: 5654 LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW------------------RDHTEFAQDLEIVDK-----EQDGRNKIKSSYEESSPTSNKWSC--------NPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTES-----LKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLK-DHNQTYLNLTLSMKKENEA---------RWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWT 7912
            L ++L N    +SE +CYF++ILN+M+S +L SL  P+++FLW MLS+ +PSK FW+  I +TE+++VIKY+FQF F  +N  T    +   P + P ++G+EKS +Y   DLIQLL +F HR  L + GLW                  +   + +QDLE          Q  R + + S +E    SN W+C        N    ++ F+  + + K     DVY FMFL + + F+II+FG+ +FG  + +AD A   +  +++P  F+ M++ QF  ++IDRAL+LRK V GK IFQ+  V+ IH W+FF LP +T++ FN     QL YFVKCIYFALSAYQ++ GYP RILGNFLT+ +N++NLFLF+G+ +VPFL ELR VMDW+WTDT+++L +WM VED++  IF++KC R +E +YP  +G  ++   KY +GGL++ F     W PL   S + +   V N PI+ T +  +GGY PLF   +++ +++      ++ +   ++       ++  +   D+    I+GSS  VW I+PPS E+++ +L++  S        + Q    +  +   T+EK  +       +  +  +LL+ +        V I  +FP+++ A     +     L+ D  ++YL++ + + +   A          WW I          + +    +  + L + IF+++VS    G L + YGI+G+Y + + V  + +R F+S+IS+ I  EELP VDRIL L  +IY+VRE     LEE+L AKLIFLYRS ETMIKWT
Sbjct: 1420 LLLALYNFVAAHSELLCYFIIILNNMVSASLISLFLPILIFLWGMLSIHKPSKRFWMTAIIFTEVMVVIKYLFQFGFFPWNNYTILVRNEGKPFFPPRVLGLEKSDSYIKYDLIQLLMLFFHRSLLMSYGLWDRKDLDLEERTPGKDKGSKTEIQASQDLEPAGGSSSSLRQRKRKESQGSVQERGAESN-WTCAVQFTSLRNIYQPVKAFFHDILHTKNRAATDVYAFMFLADVVDFVIIVFGFWAFGKHSAAADIASS-LSDDQVPEAFLVMVLIQFSTMVIDRALYLRKTVLGKLIFQVILVIGIHVWMFFILPAVTERMFNQNTVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIIVFLICIIWFPLLFMSLVRSVVGVVNHPIDVTVTFKLGGYEPLFTMSAQQQSIQPFTPQQYEALTYEFERQPTAMQFITLYSYEDIVTARIEGSSGSVWGISPPSREQMRKELQNGSSDITLRFTWDFQRDLAKGGTVEHTSEKHTKDLEPGSQERMELADLLQGVRDTP----VSIQHLFPKYIRAPNGPEANPVKQLQPDEEESYLDVEVQLNRMRVAEGNSTSSFVEWWVI----------TLKDCEGEDCNILPMVIFNDKVSPPSLGFL-AGYGIMGLYVSIVLVIGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIYVVRERGELELEEELYAKLIFLYRSPETMIKWT 2205

HSP 2 Score: 368.237 bits (944), Expect = 1.148e-101
Identity = 270/896 (30.13%), Postives = 433/896 (48.33%), Query Frame = 2 
Query: 1643 AWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNL-TELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLN----IXXXXXXXXNVSAFIED------VNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSM------------DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSID-DSLI--NLFKFCINFA----FYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-----LTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIEN--------SLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASR 4201
             WS+TY SW++F+LLL AC +WM+ + R+  +  SP I+ Y   L  +QY++  +L  ELP    T  G  + LS++G  +   P   +  ++ + + FWL L  F+T+  L   K    L +         +      N+     +++ SF      KYWI VC    + VS    +VV++IVYMLL +  L+ F   YS WRK +  FWW V+ Y+++VL+ IYT+QF +FP  WKN T L++E L DIGL+ +  S+LF  +L P  FL+  I+Q+ YFH+PF+ ++++       +   G F  +        T        SA   D      V     ++  K  +    +   +WR  E H  K+V    V   + E +  N + ++L     PF +   +       W S+ ++ KM+YQL  VN   +S+NC+    N N S+            + ID A W G+ K      +I     +L++     +V  HQ  + K     KP    +FP+   + +D DSL+  ++F  C ++     F  L   ++F+V +   C  + + +             QR   +K+W  Y +FL   L  +Y IC+G+PP LC  YP        +   L +WL+LP +   P +  +++DF   + VA Q++VFI E            V  Y   ++RP   N +P  I+        SY+D +K A+F + +W  L +VF TG   I++F LGY++  F  L  G  ++ +     +  W+ +I YN  VILSK  L L+ C ++  M    FCW+I LF + C     ++   +  +R    P    ++G+ WD  CFLF++LQR++F++  F HVVLDL   +   SR
Sbjct:  293 VWSITYHSWLTFVLLLWACLIWMVRNRRQFAMLCSPFILMYGVTLCSLQYVWSMDLREELP----TQLG-FMKLSQLGLVRAPYPCLNMGALLLYTLTFWLLLHQFVTEKFLKRKKFMSPLLEVTVAGGPTCEK-----NLLKRFGEQVKSFY----AKYWIYVCGGMFIVVSFAGRLVVYKIVYMLLFLLCLVLFQVYYSLWRKLLTFFWWLVVAYTMLVLITIYTFQFEEFPEYWKNLTNLTDEQLGDIGLERFSVSELFTSILIPGFFLLACILQLHYFHRPFMHMTNL-----AHASSQGSFHSHERYAQLNLTLLEEDEEESAHGADLSKWDLVTQRLSVLSFKFSELLHRLQVFLWRLLELHVLKLVALYSVWVALQEVSVMNFLFVVLWAFAMPFSRFQHMASCLCTIWTSIIIVCKMLYQLTVVNPLEYSSNCTQPLLN-NTSLLEDEILNSTLYREPIDPANWFGIRKGYPNLGYIQNHLQILLLLVFEAIVYRHQEFYRKQYQLEKPHIQAVFPDVYREHLDQDSLVLNDVFISCNSYIHLMHFSILCFRMNFMV-IFHGCWLIVILTR-----------RQRVNIAKLWPKYCVFLIFFLLWQYMICLGIPPVLCIDYPWRWDTFVPVNSALIKWLYLPDFYTTPKSVNLISDFVLLIGVAQQWKVFINEKKEEWYTMAGENVEEYEAPKDRP---NPVPNFIN------CQSYLDMVKVAVFRYLFWFVLTVVFITGATRISVFGLGYLMSCFYLLLSGTTLLQKPMKAKLVLWDCLILYNITVILSKNMLSLLSCVFVQQM-QTNFCWVIQLFSLVCTVKGYYNPQDMDKDRDCSLPVE--EAGIIWDSICFLFLLLQRRVFLSCYFRHVVLDLRASSLQTSR 1144
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Mouse
Match: Piezo2 (piezo-type mechanosensitive ion channel component 2 [Source:MGI Symbol;Acc:MGI:1918781])

HSP 1 Score: 441.425 bits (1134), Expect = 6.911e-124
Identity = 228/591 (38.58%), Postives = 360/591 (60.91%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEAN---QSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKEN----EARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHN 7921
            +R+F+  + +P ++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+  +  QL YFVKC+YF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++ A KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   ++++ LK +    +++  + +   S    +L ++E  DVT   ++G+S+ +WTI+PPS +K+  +L    S    + +   +R+       ++     +  L    + ++ K I  N    S+  V I+ I+P ++ A   + S+    L   N  ++N+T+ + ++N     + WW +          +  +I  Q    L + +F+++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR  
Sbjct: 2172 IRQFFYDLIHPDYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMDNSKYNEFLKSFGPNSGAMQFLENYEREDVTVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIATDKLSFPLAVATRNSIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLSEN-NFMNITIILFRDNVTKSNSEWWVLN--------LTGSRIFNQGSQALELVVFNDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTREK 2751

HSP 2 Score: 244.202 bits (622), Expect = 9.421e-64
Identity = 175/602 (29.07%), Postives = 302/602 (50.17%), Query Frame = 2 
Query: 2642 IIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN--------FNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS----SVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGD 4372
            ++  K  ++F  +   +W   E H  KIV   I+   + E +  N V +I      P+ KL     +    W  + ++ KM+YQL+T+   N+S NCSL   N         NKS+     +D  +W+GL K +    ++     +L + A    V  HQ  +    N T P +  IF + T   +DD LIN  K+ +N+ FYK GLE  F+++V V   R+D Y++++   L+ +    +RK  +++W  Y  FL  ++  +Y +C+G+PP  C+ YP         +N+ +WL+ P +   P+   ++ DF   +  +LQ ++F  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  IF + +W  L I+F TG   I++FC+GY++  F +L  G +++L+   +++  W+ +I YN FVI  K  L +  C Y+  ++ +  CW+I  F + C          +   +M  D       S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E+  +D++K ++D+I  RQ ++ K +     L   SG+
Sbjct:  920 VLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKEVSLFNYVFLISWAFALPYAKLRRAASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIPLHELNKSLLYSAPVDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTVYRHQEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFVNYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYPWRFKGAYFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIHCR-SYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGALV-RNSCWLIQAFSLACT---------VKGYQMPEDDSRCKLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKKGKERMLSLTQESGE 1509

HSP 3 Score: 186.808 bits (473), Expect = 2.483e-46
Identity = 114/350 (32.57%), Postives = 186/350 (53.14%), Query Frame = 2 
Query: 1580 LLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNE-ILNDSKFDQSSNADSEAYFGNV------------------------------------DNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN 2518
            ++++    ++ S++   IAMMAWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V YA +L+++QYI+ F   ELPE               GF +   P G LA  I F + FWL LR  +T+    A ++ E +L++ K       + +    +V                                    D  I K + + +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WRK +  FW  V++Y+++VL+ IYTYQF  FP LW+N TGL +E L+D+GLK +  ++LF  +  P  FL+V I+ + YFH  FL+L+ + 
Sbjct:  489 MVAVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIWSF---ELPEIKKVP----------GFLEKKEP-GELASKILFTITFWLLLRQHLTEQ--KALREKEALLSEVKIGSQELEEKDEELQDVQVEGEPTEKEEEEEEEIKEERHEVKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLK 822

HSP 4 Score: 107.842 bits (268), Expect = 1.990e-22
Identity = 72/151 (47.68%), Postives = 97/151 (64.24%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFN---ETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQD 6094
            LL  ++ N  +  SE VCYF++ILNHM S ++ +L  P+++FLWAMLSVPRPS+ FW+  I YTE+ IV+KY FQF F  +N   E   +R  P + P IIG+EK + Y + DLIQLL +F HR  LK +GLW +        +IVD   D
Sbjct: 1910 LLFYAMYNTLVARSEMVCYFVIILNHMTSASIITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEIYKER--PYFPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDED-------DIVDSNTD 2051

HSP 5 Score: 78.5666 bits (192), Expect = 1.589e-13
Identity = 46/149 (30.87%), Postives = 81/149 (54.36%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKED 1279
             VVVT   G +G++ PS+ ++VY F FLG+CT+W+         F  + + L +++A H+  LYL Q +F Q  +P N++ +RL G+  ++ T C +  ++       W  + +P +++ +YY  AT  R W +   E + +    KED
Sbjct:  224 KVVVTILLGSSGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYARLFGIKSVIQTDCASTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQ---EPLVQEEMAKED 369
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Mouse
Match: Piezo2 (piezo-type mechanosensitive ion channel component 2 [Source:MGI Symbol;Acc:MGI:1918781])

HSP 1 Score: 441.425 bits (1134), Expect = 6.914e-124
Identity = 228/590 (38.64%), Postives = 360/590 (61.02%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEAN---QSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKEN----EARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRH 7918
            +R+F+  + +P ++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+  +  QL YFVKC+YF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++ A KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   ++++ LK +    +++  + +   S    +L ++E  DVT   ++G+S+ +WTI+PPS +K+  +L    S    + +   +R+       ++     +  L    + ++ K I  N    S+  V I+ I+P ++ A   + S+    L   N  ++N+T+ + ++N     + WW +          +  +I  Q    L + +F+++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR 
Sbjct: 2197 IRQFFYDLIHPDYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMDNSKYNEFLKSFGPNSGAMQFLENYEREDVTVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIATDKLSFPLAVATRNSIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENN-FMNITIILFRDNVTKSNSEWWVLN--------LTGSRIFNQGSQALELVVFNDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTRE 2775

HSP 2 Score: 243.817 bits (621), Expect = 1.339e-63
Identity = 175/602 (29.07%), Postives = 302/602 (50.17%), Query Frame = 2 
Query: 2642 IIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN--------FNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS----SVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGD 4372
            ++  K  ++F  +   +W   E H  KIV   I+   + E +  N V +I      P+ KL     +    W  + ++ KM+YQL+T+   N+S NCSL   N         NKS+     +D  +W+GL K +    ++     +L + A    V  HQ  +    N T P +  IF + T   +DD LIN  K+ +N+ FYK GLE  F+++V V   R+D Y++++   L+ +    +RK  +++W  Y  FL  ++  +Y +C+G+PP  C+ YP         +N+ +WL+ P +   P+   ++ DF   +  +LQ ++F  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  IF + +W  L I+F TG   I++FC+GY++  F +L  G +++L+   +++  W+ +I YN FVI  K  L +  C Y+  ++ +  CW+I  F + C          +   +M  D       S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E+  +D++K ++D+I  RQ ++ K +     L   SG+
Sbjct:  945 VLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKEVSLFNYVFLISWAFALPYAKLRRAASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIPLHELNKSLLYSAPVDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTVYRHQEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFVNYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYPWRFKGAYFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIHCR-SYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGALV-RNSCWLIQAFSLACT---------VKGYQMPEDDSRCKLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKKGKERMLSLTQESGE 1534

HSP 3 Score: 186.808 bits (473), Expect = 2.734e-46
Identity = 114/350 (32.57%), Postives = 186/350 (53.14%), Query Frame = 2 
Query: 1580 LLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNE-ILNDSKFDQSSNADSEAYFGNV------------------------------------DNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN 2518
            ++++    ++ S++   IAMMAWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V YA +L+++QYI+ F   ELPE               GF +   P G LA  I F + FWL LR  +T+    A ++ E +L++ K       + +    +V                                    D  I K + + +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WRK +  FW  V++Y+++VL+ IYTYQF  FP LW+N TGL +E L+D+GLK +  ++LF  +  P  FL+V I+ + YFH  FL+L+ + 
Sbjct:  489 MVAVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIWSF---ELPEIKKVP----------GFLEKKEP-GELASKILFTITFWLLLRQHLTEQ--KALREKEALLSEVKIGSQELEEKDEELQDVQVEGEPTEKEEEEEEEIKEERHEVKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLK 822

HSP 4 Score: 107.842 bits (268), Expect = 1.993e-22
Identity = 72/151 (47.68%), Postives = 97/151 (64.24%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFN---ETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQD 6094
            LL  ++ N  +  SE VCYF++ILNHM S ++ +L  P+++FLWAMLSVPRPS+ FW+  I YTE+ IV+KY FQF F  +N   E   +R  P + P IIG+EK + Y + DLIQLL +F HR  LK +GLW +        +IVD   D
Sbjct: 1935 LLFYAMYNTLVARSEMVCYFVIILNHMTSASIITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEIYKER--PYFPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDED-------DIVDSNTD 2076

HSP 5 Score: 78.5666 bits (192), Expect = 1.526e-13
Identity = 46/149 (30.87%), Postives = 81/149 (54.36%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKED 1279
             VVVT   G +G++ PS+ ++VY F FLG+CT+W+         F  + + L +++A H+  LYL Q +F Q  +P N++ +RL G+  ++ T C +  ++       W  + +P +++ +YY  AT  R W +   E + +    KED
Sbjct:  224 KVVVTILLGSSGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYARLFGIKSVIQTDCASTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQ---EPLVQEEMAKED 369
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Mouse
Match: Piezo2 (piezo-type mechanosensitive ion channel component 2 [Source:MGI Symbol;Acc:MGI:1918781])

HSP 1 Score: 441.425 bits (1134), Expect = 7.546e-124
Identity = 228/591 (38.58%), Postives = 360/591 (60.91%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEAN---QSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKEN----EARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHN 7921
            +R+F+  + +P ++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+  +  QL YFVKC+YF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++ A KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   ++++ LK +    +++  + +   S    +L ++E  DVT   ++G+S+ +WTI+PPS +K+  +L    S    + +   +R+       ++     +  L    + ++ K I  N    S+  V I+ I+P ++ A   + S+    L   N  ++N+T+ + ++N     + WW +          +  +I  Q    L + +F+++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR  
Sbjct: 2243 IRQFFYDLIHPDYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMDNSKYNEFLKSFGPNSGAMQFLENYEREDVTVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIATDKLSFPLAVATRNSIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENN-FMNITIILFRDNVTKSNSEWWVLN--------LTGSRIFNQGSQALELVVFNDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTREK 2822

HSP 2 Score: 244.202 bits (622), Expect = 1.070e-63
Identity = 175/602 (29.07%), Postives = 302/602 (50.17%), Query Frame = 2 
Query: 2642 IIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN--------FNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS----SVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGD 4372
            ++  K  ++F  +   +W   E H  KIV   I+   + E +  N V +I      P+ KL     +    W  + ++ KM+YQL+T+   N+S NCSL   N         NKS+     +D  +W+GL K +    ++     +L + A    V  HQ  +    N T P +  IF + T   +DD LIN  K+ +N+ FYK GLE  F+++V V   R+D Y++++   L+ +    +RK  +++W  Y  FL  ++  +Y +C+G+PP  C+ YP         +N+ +WL+ P +   P+   ++ DF   +  +LQ ++F  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  IF + +W  L I+F TG   I++FC+GY++  F +L  G +++L+   +++  W+ +I YN FVI  K  L +  C Y+  ++ +  CW+I  F + C          +   +M  D       S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E+  +D++K ++D+I  RQ ++ K +     L   SG+
Sbjct:  935 VLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKEVSLFNYVFLISWAFALPYAKLRRAASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIPLHELNKSLLYSAPVDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTVYRHQEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFVNYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYPWRFKGAYFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIHCR-SYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGALV-RNSCWLIQAFSLACT---------VKGYQMPEDDSRCKLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKKGKERMLSLTQESGE 1524

HSP 3 Score: 181.03 bits (458), Expect = 1.556e-44
Identity = 114/351 (32.48%), Postives = 185/351 (52.71%), Query Frame = 2 
Query: 1580 LLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNE-ILNDSKFDQSSNADSEAYFG-------------------------------------NVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN 2518
            ++++    ++ S++   IAMMAWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V YA +L+++QYI+ F   ELPE               GF +   P G LA  I F + FWL LR  +T+    A ++ E +L++ K       + E                                         + D  I K + + +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WRK +  FW  V++Y+++VL+ IYTYQF  FP LW+N TGL +E L+D+GLK +  ++LF  +  P  FL+V I+ + YFH  FL+L+ + 
Sbjct:  489 MVAVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIWSF---ELPEIKKVP----------GFLEKKEP-GELASKILFTITFWLLLRQHLTEQ--KALREKEALLSEVKIGSQELEEKEDEELQDVQVEGEPTEKEEEEEEEIKEERHEVKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLK 823

HSP 4 Score: 107.842 bits (268), Expect = 1.886e-22
Identity = 72/151 (47.68%), Postives = 97/151 (64.24%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFN---ETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQD 6094
            LL  ++ N  +  SE VCYF++ILNHM S ++ +L  P+++FLWAMLSVPRPS+ FW+  I YTE+ IV+KY FQF F  +N   E   +R  P + P IIG+EK + Y + DLIQLL +F HR  LK +GLW +        +IVD   D
Sbjct: 1981 LLFYAMYNTLVARSEMVCYFVIILNHMTSASIITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEIYKER--PYFPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDED-------DIVDSNTD 2122

HSP 5 Score: 78.5666 bits (192), Expect = 1.691e-13
Identity = 46/149 (30.87%), Postives = 81/149 (54.36%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKED 1279
             VVVT   G +G++ PS+ ++VY F FLG+CT+W+         F  + + L +++A H+  LYL Q +F Q  +P N++ +RL G+  ++ T C +  ++       W  + +P +++ +YY  AT  R W +   E + +    KED
Sbjct:  224 KVVVTILLGSSGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYARLFGIKSVIQTDCASTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQ---EPLVQEEMAKED 369
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Mouse
Match: Piezo1 (piezo-type mechanosensitive ion channel component 1 [Source:MGI Symbol;Acc:MGI:3603204])

HSP 1 Score: 435.647 bits (1119), Expect = 2.815e-122
Identity = 348/1203 (28.93%), Postives = 569/1203 (47.30%), Query Frame = 2 
Query:  848 VVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTS--CQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNR-----------------------FLYGDSREV---------GPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCS--------LYTTNFNKSM---DQIDNAKWIGLEK----VNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRK-ICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-----LTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGG--------GRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWD-RNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEE 4264
            +V+   AGI  PS  +SVYL  FL ICT+W+C   +    F  + + +  + A H+  LY  Q  F+Q  LP  N  +RL GL   V+          V    H W  Y+SP I++ +YY   +       K  +S P      E  K +  +          L P+ +A + T           GE      P+  LD+     +T+     S +R  Q P    L + +  SPL             + +  +  S+V   IAMM WS+ Y SW++F+LLL AC +W +    +  +  SP I+ Y   L  ++Y++   L ELP    T  G  V L ++G      P   L  M+ +L+ FWL LR F+ + LL   K    L +      + AD+E         + + +   + GI  KYWI VC    + VS    +VV++IVYM L +  L  F   Y+ WRK + VFWW V+ Y+++VL+ +YT+QF  FP  W+N TG ++E L D+GL+ +  S+LF  +L P  FL+  I+Q+ YFH+PF++L+ +                           + +  EV         GP +       ++S    V+  + D+ ++F  ++ +++ F       V R  E H  K+V    V   + E +  N++L++L     P+ +   +    S  W  + ++ KM+YQLK VN   +S+NC+        L     N+S+     +D A W G+ K    +   Q+H+     ++    ++   ++++RQ  + P   +     +  + T Q +D  L++  K+ INF FYK GLE+ F++ V V   R++   +++   L+  L  +R+   +++W  Y LFL + L  +Y +C+G+PP LC  YP        +   L +WL+LP +   P++  +++DF   +  + Q++VF  E +       G         R  P   N +P     +F+  + SY+D LK A+F + +WL L +VF  G   I++F LGY++  F  L  G  ++ +     +  W+ +I YN  VI+SK  L L+ C +++ M S  FCW+I LF + C     +D + M+  +R    P    ++G+ WD  CF F++LQR+IF++  F HV  DL      ASRG  L N   + SI   +  EE
Sbjct:  211 IVLLALAGIAHPSAFSSVYLVVFLAICTWWSCHFPLSPLGFNTLCVMVSCFGAGHLICLYCYQTPFIQDMLPPGNIWARLFGLKNFVDLPNYSSPNALVLNTKHAWPIYVSPGILLLLYYTATS-----LLKLHKSCP-----SELRKETPREDEEHELELDHLEPEPQARDAT----------QGEMPMTTEPD--LDNCTVHVLTSQ----SPVR--QRPVRPRLAELKEMSPLH-----------GLGHLIMDQSYVCALIAMMVWSIMYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGLTLCCLRYVWAMELPELP----TTLGP-VSLHQLGLEHTRYPCLDLGAMLLYLLTFWLLLRQFVKEKLLKKQKVPAALLEV-----TVADTEP---TQTQTLLRSLGELVTGIYVKYWIYVCAGMFIVVSFAGRLVVYKIVYMFLFLLCLTLFQVYYTLWRKLLRVFWWLVVAYTMLVLIAVYTFQFQDFPTYWRNLTGFTDEQLGDLGLEQFSVSELFSSILIPGFFLLACILQLHYFHRPFMQLTDLEHVPPPGTRHPRWAHRQDAVSEAPLLEHQEEEEVFREDGQSMDGPHQATQVPEGTASKWGLVADRLLDLAASFSAVLTRIQVF-------VRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCIIIVCKMLYQLKIVNPHEYSSNCTEPFPNNTNLQPLEINQSLLYRGPVDPANWFGVRKGYPNLGYIQNHLQILLLLVFEAVVYRRQEHYRRQHQQAPLPAQ----AVCADGTRQRLDQDLLSCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFMVILHGCWLVAILTRRRREAIARLWPNYCLFLTLFLLYQYLLCLGMPPALCIDYPWRWSKAIPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGINTDHLEPLRGEP---NPIP-----NFIHCR-SYLDMLKVAVFRYLFWLVLVVVFVAGATRISIFGLGYLLACFYLLLFGTTLLQKDTRAQLVLWDCLILYNVTVIISKNMLSLLSCVFVEQMQSN-FCWVIQLFSLVCTVKGYYDPKEMMTRDRDCLLPVE--EAGIIWDSICFFFLLLQRRIFLSHYFLHVSADLKATALQASRGFALYNAANLKSINFHRQIEE 1338

HSP 2 Score: 382.489 bits (981), Expect = 6.369e-106
Identity = 224/606 (36.96%), Postives = 350/606 (57.76%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKL-RSTESLKINMQAICERRSSDSKTTEKM-VRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLK-DHNQTYLNLTLSMKKENEA----------------RWW--EIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            ++RF+  + + K+    DVY  MFL + +  +IIIFG+ +FG  + + D A   +  +++P  F+ M++ QF  ++IDRAL+LRK V GK  FQ+  V+ IH W+FF LP +T++ F+     QL YFVKCIYFALSAYQ++ GYP RILGNFLT+ +N++NLFLF+G+ +VPFL ELR VMDW+WTDT+++L +WM VED++  IF++KC R +E +YP  +G  ++   KY +GGL++ F     W PL   S I +   V N PI+ T ++ +GGY PLF   +++ ++       ++++ + +  +     ++  +   D+    I+GSS  +W I+PPS  ++K +L   T  + +      +R  +   T E    +HT     +   ++ L + +E      VV I  +FP+++ A     +     L+ D  + YL + + +++E                    WW  E+Q+              K   + L + IFS++VS    G L + YGI+G+Y + + V  + +R F+S+IS+ I  EELP VDRIL L  +I+LVRE +   LEE+L AKLIFLYRS ETMIKWTR  +
Sbjct: 1957 LQRFFHDILHTKYRAATDVYALMFLADIVDIIIIIFGFWAFGKHSAATDIASS-LSDDQVPQAFLFMLLVQFGTMVIDRALYLRKTVLGKLAFQVVLVVAIHIWMFFILPAVTERMFSQNAVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLIRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIVPFTPQAYEELSQQFDPYPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKQELYNGTADITLRFTWNFQRDLAKGGTVEYTNEKHTLELAPNSTARRQLAQLLEGRPDQSVV-IPHLFPKYIRAPNGPEANPVKQLQPDEEEDYLGVRIQLRREQVGTGASGEQAGTKASDFLEWWVIELQDC-------------KADCNLLPMVIFSDKVSPPSLGFL-AGYGIVGLYVSIVLVVGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTRERE 2546

HSP 3 Score: 114.39 bits (285), Expect = 1.912e-24
Identity = 76/229 (33.19%), Postives = 122/229 (53.28%), Query Frame = 2 
Query: 5501 KISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXXXXXXXXXLLAISLG-NVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRV---DPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTE--FAQD-LEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPI 6166
            +    + G  EL A     +   S   ++ +     L+E E   ++    L  +  G      +SE +CYF++ILNHM++ +  SL  P++VFLWAML++PRPSK FW+  I +TE+++V KY+FQF F  +N     R     P + P I+G+EK+ +Y   DL+QL+ +F HR  L   GLW DH E  + +D      K+++ + + ++  E  S T       P+
Sbjct: 1622 QAGTSLHGSQELLANARTRMRTASELLLDRRLHIPELEEAERFEAQQGRTLRLLRAGYQCVAAHSELLCYFIIILNHMVTASAASLVLPVLVFLWAMLTIPRPSKRFWMTAIVFTEVMVVTKYLFQFGFFPWNSYVVLRRYENKPYFPPRILGLEKTDSYIKYDLVQLMALFFHRSQLLCYGLW-DHEEDRYPKDHCRSSVKDREAKEEPEAKLESQSETGTGHPKEPV 1849
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Mouse
Match: Piezo1 (piezo-type mechanosensitive ion channel component 1 [Source:MGI Symbol;Acc:MGI:3603204])

HSP 1 Score: 435.647 bits (1119), Expect = 2.942e-122
Identity = 348/1203 (28.93%), Postives = 569/1203 (47.30%), Query Frame = 2 
Query:  848 VVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTS--CQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNR-----------------------FLYGDSREV---------GPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCS--------LYTTNFNKSM---DQIDNAKWIGLEK----VNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRK-ICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-----LTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGG--------GRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWD-RNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEE 4264
            +V+   AGI  PS  +SVYL  FL ICT+W+C   +    F  + + +  + A H+  LY  Q  F+Q  LP  N  +RL GL   V+          V    H W  Y+SP I++ +YY   +       K  +S P      E  K +  +          L P+ +A + T           GE      P+  LD+     +T+     S +R  Q P    L + +  SPL             + +  +  S+V   IAMM WS+ Y SW++F+LLL AC +W +    +  +  SP I+ Y   L  ++Y++   L ELP    T  G  V L ++G      P   L  M+ +L+ FWL LR F+ + LL   K    L +      + AD+E         + + +   + GI  KYWI VC    + VS    +VV++IVYM L +  L  F   Y+ WRK + VFWW V+ Y+++VL+ +YT+QF  FP  W+N TG ++E L D+GL+ +  S+LF  +L P  FL+  I+Q+ YFH+PF++L+ +                           + +  EV         GP +       ++S    V+  + D+ ++F  ++ +++ F       V R  E H  K+V    V   + E +  N++L++L     P+ +   +    S  W  + ++ KM+YQLK VN   +S+NC+        L     N+S+     +D A W G+ K    +   Q+H+     ++    ++   ++++RQ  + P   +     +  + T Q +D  L++  K+ INF FYK GLE+ F++ V V   R++   +++   L+  L  +R+   +++W  Y LFL + L  +Y +C+G+PP LC  YP        +   L +WL+LP +   P++  +++DF   +  + Q++VF  E +       G         R  P   N +P     +F+  + SY+D LK A+F + +WL L +VF  G   I++F LGY++  F  L  G  ++ +     +  W+ +I YN  VI+SK  L L+ C +++ M S  FCW+I LF + C     +D + M+  +R    P    ++G+ WD  CF F++LQR+IF++  F HV  DL      ASRG  L N   + SI   +  EE
Sbjct:  212 IVLLALAGIAHPSAFSSVYLVVFLAICTWWSCHFPLSPLGFNTLCVMVSCFGAGHLICLYCYQTPFIQDMLPPGNIWARLFGLKNFVDLPNYSSPNALVLNTKHAWPIYVSPGILLLLYYTATS-----LLKLHKSCP-----SELRKETPREDEEHELELDHLEPEPQARDAT----------QGEMPMTTEPD--LDNCTVHVLTSQ----SPVR--QRPVRPRLAELKEMSPLH-----------GLGHLIMDQSYVCALIAMMVWSIMYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGLTLCCLRYVWAMELPELP----TTLGP-VSLHQLGLEHTRYPCLDLGAMLLYLLTFWLLLRQFVKEKLLKKQKVPAALLEV-----TVADTEP---TQTQTLLRSLGELVTGIYVKYWIYVCAGMFIVVSFAGRLVVYKIVYMFLFLLCLTLFQVYYTLWRKLLRVFWWLVVAYTMLVLIAVYTFQFQDFPTYWRNLTGFTDEQLGDLGLEQFSVSELFSSILIPGFFLLACILQLHYFHRPFMQLTDLEHVPPPGTRHPRWAHRQDAVSEAPLLEHQEEEEVFREDGQSMDGPHQATQVPEGTASKWGLVADRLLDLAASFSAVLTRIQVF-------VRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCIIIVCKMLYQLKIVNPHEYSSNCTEPFPNNTNLQPLEINQSLLYRGPVDPANWFGVRKGYPNLGYIQNHLQILLLLVFEAVVYRRQEHYRRQHQQAPLPAQ----AVCADGTRQRLDQDLLSCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFMVILHGCWLVAILTRRRREAIARLWPNYCLFLTLFLLYQYLLCLGMPPALCIDYPWRWSKAIPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGINTDHLEPLRGEP---NPIP-----NFIHCR-SYLDMLKVAVFRYLFWLVLVVVFVAGATRISIFGLGYLLACFYLLLFGTTLLQKDTRAQLVLWDCLILYNVTVIISKNMLSLLSCVFVEQMQSN-FCWVIQLFSLVCTVKGYYDPKEMMTRDRDCLLPVE--EAGIIWDSICFFFLLLQRRIFLSHYFLHVSADLKATALQASRGFALYNAANLKSINFHRQIEE 1339

HSP 2 Score: 382.489 bits (981), Expect = 6.595e-106
Identity = 224/606 (36.96%), Postives = 350/606 (57.76%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKL-RSTESLKINMQAICERRSSDSKTTEKM-VRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLK-DHNQTYLNLTLSMKKENEA----------------RWW--EIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            ++RF+  + + K+    DVY  MFL + +  +IIIFG+ +FG  + + D A   +  +++P  F+ M++ QF  ++IDRAL+LRK V GK  FQ+  V+ IH W+FF LP +T++ F+     QL YFVKCIYFALSAYQ++ GYP RILGNFLT+ +N++NLFLF+G+ +VPFL ELR VMDW+WTDT+++L +WM VED++  IF++KC R +E +YP  +G  ++   KY +GGL++ F     W PL   S I +   V N PI+ T ++ +GGY PLF   +++ ++       ++++ + +  +     ++  +   D+    I+GSS  +W I+PPS  ++K +L   T  + +      +R  +   T E    +HT     +   ++ L + +E      VV I  +FP+++ A     +     L+ D  + YL + + +++E                    WW  E+Q+              K   + L + IFS++VS    G L + YGI+G+Y + + V  + +R F+S+IS+ I  EELP VDRIL L  +I+LVRE +   LEE+L AKLIFLYRS ETMIKWTR  +
Sbjct: 1958 LQRFFHDILHTKYRAATDVYALMFLADIVDIIIIIFGFWAFGKHSAATDIASS-LSDDQVPQAFLFMLLVQFGTMVIDRALYLRKTVLGKLAFQVVLVVAIHIWMFFILPAVTERMFSQNAVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLIRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIVPFTPQAYEELSQQFDPYPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKQELYNGTADITLRFTWNFQRDLAKGGTVEYTNEKHTLELAPNSTARRQLAQLLEGRPDQSVV-IPHLFPKYIRAPNGPEANPVKQLQPDEEEDYLGVRIQLRREQVGTGASGEQAGTKASDFLEWWVIELQDC-------------KADCNLLPMVIFSDKVSPPSLGFL-AGYGIVGLYVSIVLVVGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTRERE 2547

HSP 3 Score: 114.39 bits (285), Expect = 1.945e-24
Identity = 76/229 (33.19%), Postives = 122/229 (53.28%), Query Frame = 2 
Query: 5501 KISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXXXXXXXXXLLAISLG-NVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRV---DPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTE--FAQD-LEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPI 6166
            +    + G  EL A     +   S   ++ +     L+E E   ++    L  +  G      +SE +CYF++ILNHM++ +  SL  P++VFLWAML++PRPSK FW+  I +TE+++V KY+FQF F  +N     R     P + P I+G+EK+ +Y   DL+QL+ +F HR  L   GLW DH E  + +D      K+++ + + ++  E  S T       P+
Sbjct: 1623 QAGTSLHGSQELLANARTRMRTASELLLDRRLHIPELEEAERFEAQQGRTLRLLRAGYQCVAAHSELLCYFIIILNHMVTASAASLVLPVLVFLWAMLTIPRPSKRFWMTAIVFTEVMVVTKYLFQFGFFPWNSYVVLRRYENKPYFPPRILGLEKTDSYIKYDLVQLMALFFHRSQLLCYGLW-DHEEDRYPKDHCRSSVKDREAKEEPEAKLESQSETGTGHPKEPV 1850
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. UniProt/SwissProt
Match: sp|M9MSG8|PIEZO_DROME (Piezo-type mechanosensitive ion channel component OS=Drosophila melanogaster OX=7227 GN=Piezo PE=2 SV=1)

HSP 1 Score: 487.263 bits (1253), Expect = 2.470e-137
Identity = 279/804 (34.70%), Postives = 446/804 (55.47%), Query Frame = 2 
Query: 5690 SEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFI--SFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWR-----------------DHTEFAQDLEIVDKEQ---DGRNKIKSSYEESS-PTSNKWSCNPIYKMRR----------FYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPG-TDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDEN-----------DKKNLLKAIEANQSS--------YVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEAR--WWEIQEIVAGETYCS----NEKIPKQSHSNLTVFIFSERVSDNLFGHLFS---NYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            ++ +CY ++ +N +++ +L SLP P+MVFLW  LS+PRP+K FW+ LI YT+ +++IK IFQF  I  ++++  N    PL    I G+E   +YAI DLI LL +FLHR  LK+ GLW+                 D  + + +L   D  Q   D   K+     ++S P S ++S   I ++ R          F+S +   +     DVY  MFLC+F+ F +++FG+ +FG   T+S +    ++  NK+P+PF+ M++ QF+ I+IDRAL+LRK +  K IF  F V+ IH W+FF +P +T++ FNS   P + Y +KC Y  LS+YQ+KSGYP RILGNF T+ F+ +N+  FK YM +PFLYELR ++DW+  D+++ +F W+++ED+F  I++++C R+SE ++P +R   +   SK  +GG ++    IC WGPL L +        N P   + SI +G Y P+ Y  +  +++  +  + + +M   Y        ++  ++A DV  + + G+S  +W I PP  ++L   LR+  +LK        R++  +K  ++ V   +   LDE+            + + ++ I +N ++         VV I  + P+F+       +   ++L   +  Y  L + M ++NE    WWEI++      YC+    NE + K ++SN T  I     +D  F   FS     GIIG+Y  ++ +A R +++F    +  I  E+LP+VDR+L L  +IYLVRE   F LEE L AKL+FLYRS ET+IKWTR
Sbjct: 1728 TDLICYIVVFINQVVNASLISLPLPIMVFLWGTLSLPRPTKTFWVTLIAYTQAIVLIKCIFQFKLIWSNYHQLPNQ---PLTPAKIFGVENKAHYAIYDLILLLVLFLHRYLLKSQGLWKSGYKDTDNQFTKPTASIDERDDSDNLSQPDSRQLNDDAAQKLSLQVSQASLPGSPEFSKTGINQLERTKYTSSLYKFFFSLVHKSRL--ATDVYALMFLCDFVNFFVLLFGFTAFGTQQTESDEGVQTYLAENKVPIPFLIMLLVQFLLIVIDRALYLRKALVNKIIFHFFSVIGIHIWMFFVVPAVTERTFNSLAPPIIFYVIKCFYMLLSSYQIKSGYPKRILGNFFTKGFSMVNMIAFKVYMQIPFLYELRTILDWVCIDSTMTIFDWLKMEDIFSNIYLIRCTRQSETDFPAMRAQKKASLSKLIMGGTIVLLIVICIWGPLCLFALGNAVGTSNVPFHVSLSIRIGPYDPI-YTTNNYDSIFEINPEMYSQMTNAYIKEKQALTFIAGYDATDVAAVRLAGNSPSLWNIAPPDRQRLLNDLRNNHTLKARFSYSLTRKAP-AKGLKENVGDEHAISLDESFEGRAALIHMLSETHDVEPIYSNGTTNGTTPEVEEVVVIPGMIPKFIKVLNSGDAAVVSVLSPKHYDYRPLVIKMHRDNETNGLWWEIRD------YCNDTFYNETLSKFAYSNCTSGIVMYTFNDKKFPSTFSFLTAGGIIGLYTTFVLLASRFMKSFIGGQNRKIMFEDLPYVDRVLQLCLDIYLVREALEFALEEDLFAKLLFLYRSPETLIKWTR 2518

HSP 2 Score: 435.647 bits (1119), Expect = 2.313e-121
Identity = 355/1253 (28.33%), Postives = 573/1253 (45.73%), Query Frame = 2 
Query:  863 FAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWI--DYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHK----WAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILND--SKFDQSSNADSEAYF---GNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQ-EPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNL------------------NIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKV----WRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSF-FWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWK----WTAVLVVCALWHVVKYHQRQF-YKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTS--LKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNN-YGGGRNRPILCN-----ELP-KTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNML---AVNRMHGDPCSSVKSG--LHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQA-------------QHGKP----------ELNEHYLVVRSGDKYLF 4384
            FA ++ PS+    Y   FL   T+WA   + +   FA +   +++   +H   +   Q  ++Q +L +   ++RL+GL  L+ + C     V  Y ++     YL+P  + + Y+  A  T+   +      PR+      ++ S+ K       E            +GS +  SV++ G        +  L+S              +  + +  + ++LD                   +S+     +NS++FT I MMAWS+ Y SW++F+LLLSA  LWM+P+ RKA +  SP IV YA  L+I QYIYG +L   ELP    TA    ++L +IGF +       P  PL V  +F+++FW+T R F  +      +++  L D  +    +  +   +Y    G   +   KK    +  +  + WI +    +   +I  E +  FRI YM L ++FL+ F  S   W K MY FW F+I Y++ +L+ IYTYQF++F   W +   +S  + +DIGLK Y+  DLF  L++P + +++ ++QV YFHK F+  S   + L G S +  P E                        ++ ++    + F   V    +I   K+K   E I+       WRF E H  K V        ++E    +I+ +   V+G    K   ++++    F  ++ VL KMIYQ++ ++    +  CS   T         +NA+WIGL K +     +      +   +V+  +  V+   Q Q   K      P T ++FP       +  L+ L K+ +NF FYK G+E+S I  V     R D+ ++VY + L++ L  +R  C+KIW  +  F  + +  +Y + VGLPP  C  +P       E +QRW  LP   +     K++ DF   V +  Q  +F IE     N+ Y GG NR ++ +      +P      DF S   +Y D LK+ +    YW +LA+VF  G     L  LGY+I AFI+LW G +  LR    +I  W  ++ +N   IL K + Q+ GC +M   ++K  CW++ + G+ C + +  ++ ML   A   +    C  +     L WD  CF FII Q +IF +  FCH++ D    N  ASRGA +I       I  +   E+ VL KIK K+++I   Q              +HG P          E+  H    R+GD Y+F
Sbjct:  223 FAAVLRPSVPGGFYFLIFLLSGTYWATC-QTLQRGFALLLRCVMVVLVLHSLSIVSYQTPWMQSHLNHTTLTARLIGLEPLIESYCSPDIRVFLYNNKLSLDSYLNPFALFFAYFALALTTKHLIK------PRL------VRQSTRKARTPQPLE------------SGSSVAPSVTQRGN-------DMQLES------------MEQRSEQENTTTSILDQISYG-------------FVSVGGFIYQNSYIFTNILMMAWSIVYHSWLTFVLLLSANVLWMIPNQRKAMMRSSPFIVLYAEALLIAQYIYGMDLNNEELPTSVPTAG---INLQQIGFERPIENQMRPCVPLIVKTAFVLMFWVTSRQFFKEK--RDRRRDSTLADFIAPLQITVGSAGSSYLINDGKKTSKFLKKAGDVIKNLLVRLWIWLLVLVIFLCAITGENMTGFRICYMALFLFFLLVFQSSSKAWVKIMYGFWLFLIFYAMSILILIYTYQFDKFDTYWSDYLNVSATLQKDIGLKRYQTKDLFLHLVSPTIIVILTVIQVHYFHKRFIA-SLQQQPLAGGSAQQKPTETTALEPAPSKRRGSAGSLRKSQGPSAEAAPGATTDFETSVRDLVRISFRKIKNKSEYIFKNFKDVFWRFLELHIMKAVYIAAFVCSVSEVCVLHIIFVGFCVLGATSRKAVQVVISRLISFIVTVIVLSKMIYQIEYLSHSQHNVVCSDNRTA--------NNAEWIGLTKADKVTGGLMSLLRTYIIYMVIVTMHAVISLRQLQMRVKIGALNAPPTKLLFPNIIRADAEKDLVGLVKYLLNFGFYKFGIEISLIALVSTITYRQDIVAVVYALWLVVLLLLRRSQCAKIWGVFQAFFAISILTQYIVLVGLPPSSCLVFPWDEGPFGEGIQRWAMLPGALHFNHVPKLIFDFIVLVILNRQKSIFCIEQRYASNDDYPGGSNRSVIADIAQLGRVPFDNPTHDFCSYIRNYSDILKNGVLCGFYWFTLAVVFLAGTNIADLLALGYLIGAFIFLWQGSDFYLRPIHTIIFRWKWLLAFNVANILIKTSFQMAGCLFMT-QLTKDCCWLVHMLGITCTSNVLTEQIMLPEEAELALKPGECPKITHQVVLLWDTICFAFIIFQLRIFKSHYFCHIITDTKANNILASRGADIIESLRHKQIAHRHDHEKQVLHKIKRKMERIRATQQKMLRPLDKQTHFDEHGYPLPAPTVRRRKEIKLHPHATRAGDYYMF 1403
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. UniProt/SwissProt
Match: sp|Q92508|PIEZ1_HUMAN (Piezo-type mechanosensitive ion channel component 1 OS=Homo sapiens OX=9606 GN=PIEZO1 PE=1 SV=4)

HSP 1 Score: 461.84 bits (1187), Expect = 1.802e-129
Identity = 377/1422 (26.51%), Postives = 643/1422 (45.22%), Query Frame = 2 
Query:  308 FSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVN-TSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYK----EDIKMSSLKQ-SNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRF-LYG--------------------------------------DSREVG-----PFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCS--------LYTTNFNKSM---DQIDNAKWIGLEK----VNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKP-ETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQ-RKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-----LTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGG---GRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNE 4345
             +L I L  +P + + L   +C+ +  ++S  IG+T L        +RLV PD   L+ S V L    +    + Q P H ++  +D  +   S      ++    P+R   RL         +L   +G +L+                                              V +   AGI  PS L+SVYL  FL +CT+WAC   + T  F+ + + +  + A H+  LY  Q+   Q  LP     +R+LGL   V  T+C +   +   T   W  Y SP +++ + Y  AT + R     R S  R  + K     +++++ L Q   E + +  ++P                           P+   D+    ++T    + S +R    P  A               P E   L S+ +  +  S+V   IAMM WS+TY SW++F+LLL AC +W +    +  +  SP I+ Y   L  ++Y++  +L   PE   T     V L ++G      P   L  M+ + + FWL LR F+ + LL  ++    L +      + AD+E         + + +   + G+  KYWI VC    + VS    +VV++IVYM L +  L  F   YS WRK +  FWW V+ Y+++VL+ +YT+QF  FP  W+N TG ++E L D+GL+ +  S+LF  +L P  FL+  I+Q+ YFH+PF++L+ M    L G                                      DSR+ G     P +    +   ++    V+  + ++ + F  ++ +++ F         R  E H  K+V    V   + E +  N++L++L     P+ +   +    S  W  + ++ KM+YQLK VN   +S+NC+        L  T  ++S+     +D A W G+ K    +   Q+H+      +++  ++  + Y +++ Y+  +   P     +F   T Q +D  L+   K+ INF FYK GLE+ F++ V V   R++    ++   L+  L  + R+  +++W  Y LFL + L  +Y +C+G+PP LC  YP        +   L +WL+LP +   P++  +++DF   +  + Q++VF  E +       G    R  P+     P     +F+  + SY+D LK A+F + +WL L +VF TG   I++F LGY++  F  L  G  ++ R     +  W+ +I YN  VI+SK  L L+ C +++ M +  FCW+I LF + C     +D   + ++R         ++G+ WD  CF F++LQR++F++  + HV  DL      ASRG  L N   + SI   +  EE  L ++K ++++I  +Q +H +  ++ 
Sbjct:   75 LALQICLHIVPRL-DQLLGPSCS-RWETLSRHIGVTRLDLKDIPNAIRLVAPDLGILVVSSVCLGICGRLARNTRQSP-HPRELDDDERDVDASPTAGLQEAATLAPTR-RSRLAARFRVTAHWLLVAAGRVLA----------------------------------------------VTLLALAGIAHPSALSSVYLLLFLALCTWWACHFPISTRGFSRLCVAVGCFGAGHLICLYCYQMPLAQALLPPAGIWARVLGLKDFVGPTNCSSPHALVLNTGLDWPVYASPGVLLLLCY--ATASLRKLRAYRPSGQRKEAAKGYEARELELAELDQWPQERESDQHVVPTA-------------------------PDTEADNCIVHELTG---QSSVLRRPVRPKRA--------------EPREASPLHSLGHLIMDQSYVCALIAMMVWSITYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGMTLCCLRYVWAMDLR--PELPTTLG--PVSLRQLGLEHTRYPCLDLGAMLLYTLTFWLLLRQFVKEKLLKWAESPAALTEV-----TVADTEP---TRTQTLLQSLGELVKGVYAKYWIYVCAGMFIVVSFAGRLVVYKIVYMFLFLLCLTLFQVYYSLWRKLLKAFWWLVVAYTMLVLIAVYTFQFQDFPAYWRNLTGFTDEQLGDLGLEQFSVSELFSSILVPGFFLLACILQLHYFHRPFMQLTDMEHVSLPGTRLPRWAHRQDAVSGTPLLREEQQEHQQQQQEEEEEEEDSRDEGLGVATPHQAT-QVPEGAAKWGLVAERLLELAAGFSDVLSRVQVFLR-------RLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCVIIVCKMLYQLKVVNPQEYSSNCTEPFPNSTNLLPTEISQSLLYRGPVDPANWFGVRKGFPNLGYIQNHL-----QVLLLLVFEAIVYRRQEHYRRQHQLAPLPAQAVFASGTRQQLDQDLLGCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFLVTLHGCWLVAILTRRHRQAIARLWPNYCLFLALFLLYQYLLCLGMPPALCIDYPWRWSRAVPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGVNTDRLEPLRGEPNPV---PNFIHCR-SYLDMLKVAVFRYLFWLVLVVVFVTGATRISIFGLGYLLACFYLLLFGTALLQRDTRARLVLWDCLILYNVTVIISKNMLSLLACVFVEQMQTG-FCWVIQLFSLVCTVKGYYDPKEM-MDRDQDCLLPVEEAGIIWDSVCFFFLLLQRRVFLSHYYLHVRADLQATALLASRGFALYNAANLKSIDFHRRIEEKSLAQLKRQMERIRAKQEKHRQGRVDR 1371

HSP 2 Score: 396.356 bits (1017), Expect = 2.590e-109
Identity = 225/594 (37.88%), Postives = 347/594 (58.42%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKL-RSTESLKINMQAICERRSSDSKTTEKM-VRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQT-YLNLTLSMKKENEA------RWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            +RRF+  + + K+    DVY  MFL + + F+IIIFG+ +FG  + + D     +  +++P  F+ M++ QF  +++DRAL+LRK V GK  FQ+  VL IH W+FF LP +T++ FN  +  QL YFVKCIYFALSAYQ++ GYP RILGNFLT+ +N++NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  WM VED++  IF++KC R +E +YP  +G  ++   KY +GGL++ F     W PL   S + +   V N PI+ T ++ +GGY PLF   +++ ++       ++++   +        ++  +   D+    I+GSS  +W I+PPS  ++K +L   T  + +      +R  +   T E    +H      +   ++ L   +E      VV I  +FP+++ A     +     L+ + +  YL + + +++E  A       WW I E+    T C          + L + IFS++VS    G L + YGI+G+Y + + V  + +R F+S+IS+ I  EELP VDRIL L  +I+LVRE +   LEE+L AKLIFLYRS ETMIKWTR  +
Sbjct: 1942 LRRFFHDILHTKYRAATDVYALMFLADVVDFIIIIFGFWAFGKHSAATDITSS-LSDDQVPEAFLVMLLIQFSTMVVDRALYLRKTVLGKLAFQVALVLAIHLWMFFILPAVTERMFNQNVVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSSWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLVRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIIPFTAQAYEELSRQFDPQPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKRELYNGTADITLRFTWNFQRDLAKGGTVEYANEKHMLALAPNSTARRQLASLLEGTSDQSVV-IPNLFPKYIRAPNGPEANPVKQLQPNEEADYLGVRIQLRREQGAGATGFLEWWVI-ELQECRTDC----------NLLPMVIFSDKVSPPSLGFL-AGYGIMGLYVSIVLVIGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTREKE 2521

HSP 3 Score: 115.931 bits (289), Expect = 5.477e-24
Identity = 62/126 (49.21%), Postives = 85/126 (67.46%), Query Frame = 2 
Query: 5687 YSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRV---DPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTE 6055
            +SE +CYF++ILNHM++ +  SL  P++VFLWAMLS+PRPSK FW+  I +TEI +V+KY+FQF F  +N     R     P + P I+G+EK+  Y   DL+QL+ +F HR  L   GLW DH E
Sbjct: 1686 HSELLCYFIIILNHMVTASAGSLVLPVLVFLWAMLSIPRPSKRFWMTAIVFTEIAVVVKYLFQFGFFPWNSHVVLRRYENKPYFPPRILGLEKTDGYIKYDLVQLMALFFHRSQLLCYGLW-DHEE 1810
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. UniProt/SwissProt
Match: sp|Q9H5I5|PIEZ2_HUMAN (Piezo-type mechanosensitive ion channel component 2 OS=Homo sapiens OX=9606 GN=PIEZO2 PE=1 SV=2)

HSP 1 Score: 444.891 bits (1143), Expect = 3.921e-124
Identity = 226/588 (38.44%), Postives = 362/588 (61.56%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEAN---QSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARW---WEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            +++F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+  +  QL YFVKC+YF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++   KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   ++++ LK + + +F+K  + +   +    +L ++E  D+T   ++G+S+ +WTI+PPS +K+  +L    S    + +   +R+       ++     +  L    +KN+ K I  N    S   V I+ I+P ++ A   + S+    L   N  ++++T+ + ++N  ++   W +  +     Y  N +        L + +F+++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR
Sbjct: 2171 IKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENN-FMDITIILSRDNTTKYNSEWWVLNLTGNRIYNPNSQ-------ALELVVFNDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTR 2748

HSP 2 Score: 252.677 bits (644), Expect = 1.819e-65
Identity = 179/586 (30.55%), Postives = 300/586 (51.19%), Query Frame = 2 
Query: 2642 IIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN--------FNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS--SVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGK 4330
            ++  K  ++F  +   +W   E H  KIV   I+   + E +  N V +I      P+ KL  +  +    W  + ++ KM+YQL+T+   N+S NCSL   N         NKS+     ID  +W+GL K +    ++     +L + A    +  HQ  +    N T P +  IF + T   +DD LIN  K+ IN+ FYK GLE  F+++V V   R+D Y++++   L+ +    +RK  ++IW  Y  FL  ++  +Y IC+G+PP  C+ YP      S  +N+ +WL+ P +   P+   ++ DF   +  +LQ ++F  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  IF + +W  L I+F TG   I++FC+GY++  F +L  G +++L+   +++  W+ +I YN FVI  K  L +  C Y+  ++    CW+I  F + C         M A N     PC+  S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E+  +D++K ++D+I  RQ ++ K
Sbjct:  918 VLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIPFNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIHCR-SYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNS-CWLIQAFSLACTVK---GYQMPAAN----SPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKK 1493

HSP 3 Score: 248.054 bits (632), Expect = 4.166e-64
Identity = 202/780 (25.90%), Postives = 343/780 (43.97%), Query Frame = 2 
Query:  398 HQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNH-NNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEY------QTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPL-----------------------------LLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVD---------------------------------NMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN 2518
             QIG  +LKG      +R+ +PD    I S+ + +  R    K    P+ D+ +Q +    N    +G   DS             E    E  F   +      E + +    R++    + L + +G                +     VVVT   G +G++ PS+ +SVY F FLG+CT+W+         F+ + + L +++A H+  LYL Q +F Q  +P N++ +RL G+  ++ T C +  ++       W  + +P +++ +YY  AT  R W ++     P V+           + + E D  L   P +    +  SL  ++     E       Q  ++P+  L     G+  +       +    GP  A    D   +P     P++                                ++S+    ++ S++   IAMMAWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V Y  +L+I+QYI+ F   ELPE               GF +   P G LA  I F + FWL LR  +T+      K+  +L++ K     N + +    ++                                    I K + + +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WRK +  FW  V++Y+++VL+ IYTYQF  FP LW+N TGL +E L+D+GLK +  ++LF  +  P  FL+V I+ + YFH  FL+L+ + 
Sbjct:  104 RQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQK----PVTDEAAQSNPEFENEELAEGEKIDS------------EEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFIG--------------NMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYARLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQE-----PLVQD----------EGTKEEDKALACSPIQITAGRRRSLWYATHYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKA----DLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSF---ELPEIKKVP----------GFLEKKEP-GELASKILFTITFWLLLRQHLTEQKALQEKE-ALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEEEDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLK 819

HSP 4 Score: 126.331 bits (316), Expect = 3.887e-27
Identity = 76/165 (46.06%), Postives = 102/165 (61.82%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVD-PLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW--RDHTEFAQDLEIVDKE-------QDGRNKIKS 6115
            LL  ++ N  +  SE VCYF++ILNHM+S ++ +L  P+++FLWAMLSVPRPS+ FW+  I YTE+ IV+KY FQF F  +N+      D P   P IIG+EK + Y + DLIQLL +F HR  LK +GLW   D TE     E  D E       +D  + +KS
Sbjct: 1909 LLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKS 2073
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. UniProt/SwissProt
Match: sp|Q8CD54|PIEZ2_MOUSE (Piezo-type mechanosensitive ion channel component 2 OS=Mus musculus OX=10090 GN=Piezo2 PE=1 SV=2)

HSP 1 Score: 441.425 bits (1134), Expect = 5.591e-123
Identity = 228/591 (38.58%), Postives = 360/591 (60.91%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEAN---QSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKEN----EARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHN 7921
            +R+F+  + +P ++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T++KF+  +  QL YFVKC+YF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IF+LKCWR SE  YP  RG  ++ A KY +GG+++       W PL   S I +   V N P++ + +I++GGY P+F   ++++ LK +    +++  + +   S    +L ++E  DVT   ++G+S+ +WTI+PPS +K+  +L    S    + +   +R+       ++     +  L    + ++ K I  N    S+  V I+ I+P ++ A   + S+    L   N  ++N+T+ + ++N     + WW +          +  +I  Q    L + +F+++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR  
Sbjct: 2241 IRQFFYDLIHPDYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKAVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMDNSKYNEFLKSFGPNSGAMQFLENYEREDVTVAELEGNSNSLWTISPPSKQKMIQELTDPNSCFSVVFSWSIQRNMTLGAKAEIATDKLSFPLAVATRNSIAKMIAGNDTESSNTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENN-FMNITIILFRDNVTKSNSEWWVLN--------LTGSRIFNQGSQALELVVFNDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTREK 2820

HSP 2 Score: 244.202 bits (622), Expect = 6.373e-63
Identity = 175/602 (29.07%), Postives = 302/602 (50.17%), Query Frame = 2 
Query: 2642 IIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN--------FNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDK-----DFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS----SVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGD 4372
            ++  K  ++F  +   +W   E H  KIV   I+   + E +  N V +I      P+ KL     +    W  + ++ KM+YQL+T+   N+S NCSL   N         NKS+     +D  +W+GL K +    ++     +L + A    V  HQ  +    N T P +  IF + T   +DD LIN  K+ +N+ FYK GLE  F+++V V   R+D Y++++   L+ +    +RK  +++W  Y  FL  ++  +Y +C+G+PP  C+ YP         +N+ +WL+ P +   P+   ++ DF   +  +LQ ++F  EN   V    G  N  I  N    +  +     DF+  + SY+D  K  IF + +W  L I+F TG   I++FC+GY++  F +L  G +++L+   +++  W+ +I YN FVI  K  L +  C Y+  ++ +  CW+I  F + C          +   +M  D       S ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E+  +D++K ++D+I  RQ ++ K +     L   SG+
Sbjct:  935 VLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVTVKEVSLFNYVFLISWAFALPYAKLRRAASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIPLHELNKSLLYSAPVDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTVYRHQEYYRGRNNLTAPVSKTIFHDITRLHLDDGLINCAKYFVNYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIGVLYRRRRKAIAEVWPKYCCFLACIITFQYFVCIGIPPAPCRDYPWRFKGAYFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGD-NVEICMNLDAASFSQHNPVPDFIHCR-SYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGALV-RNSCWLIQAFSLACT---------VKGYQMPEDDSRCKLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKKGKERMLSLTQESGE 1524

HSP 3 Score: 181.03 bits (458), Expect = 1.009e-43
Identity = 114/351 (32.48%), Postives = 185/351 (52.71%), Query Frame = 2 
Query: 1580 LLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNE-ILNDSKFDQSSNADSEAYFG-------------------------------------NVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN 2518
            ++++    ++ S++   IAMMAWS+TY SW++F+LL+ +C LWM+ + RK  +  SP +V YA +L+++QYI+ F   ELPE               GF +   P G LA  I F + FWL LR  +T+    A ++ E +L++ K       + E                                         + D  I K + + +  +  KYWI VC     FVS +  +V+++I+YM+L ++ +  +   Y +WRK +  FW  V++Y+++VL+ IYTYQF  FP LW+N TGL +E L+D+GLK +  ++LF  +  P  FL+V I+ + YFH  FL+L+ + 
Sbjct:  489 MVAVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYANLLLVLQYIWSF---ELPEIKKVP----------GFLEKKEP-GELASKILFTITFWLLLRQHLTEQ--KALREKEALLSEVKIGSQELEEKEDEELQDVQVEGEPTEKEEEEEEEIKEERHEVKKEEEEEVEEDDDQDIMKVLGNLVVALFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLK 823

HSP 4 Score: 107.842 bits (268), Expect = 1.308e-21
Identity = 72/151 (47.68%), Postives = 97/151 (64.24%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFN---ETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQD 6094
            LL  ++ N  +  SE VCYF++ILNHM S ++ +L  P+++FLWAMLSVPRPS+ FW+  I YTE+ IV+KY FQF F  +N   E   +R  P + P IIG+EK + Y + DLIQLL +F HR  LK +GLW +        +IVD   D
Sbjct: 1979 LLFYAMYNTLVARSEMVCYFVIILNHMTSASIITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKDLEIYKER--PYFPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDED-------DIVDSNTD 2120

HSP 5 Score: 78.5666 bits (192), Expect = 1.144e-12
Identity = 46/149 (30.87%), Postives = 81/149 (54.36%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKED 1279
             VVVT   G +G++ PS+ ++VY F FLG+CT+W+         F  + + L +++A H+  LYL Q +F Q  +P N++ +RL G+  ++ T C +  ++       W  + +P +++ +YY  AT  R W +   E + +    KED
Sbjct:  224 KVVVTILLGSSGMMLPSLTSAVYFFVFLGLCTWWSWCRTFDPLLFGCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYARLFGIKSVIQTDCASTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQ---EPLVQEEMAKED 369
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. UniProt/SwissProt
Match: sp|E2JF22|PIEZ1_MOUSE (Piezo-type mechanosensitive ion channel component 1 OS=Mus musculus OX=10090 GN=Piezo1 PE=1 SV=1)

HSP 1 Score: 435.261 bits (1118), Expect = 2.798e-121
Identity = 347/1203 (28.84%), Postives = 569/1203 (47.30%), Query Frame = 2 
Query:  848 VVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTS--CQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNR-----------------------FLYGDSREV---------GPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCS--------LYTTNFNKSM---DQIDNAKWIGLEK----VNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRK-ICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-----LTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGG--------GRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWD-RNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEE 4264
            +V+   AGI  PS  +S+YL  FL ICT+W+C   +    F  + + +  + A H+  LY  Q  F+Q  LP  N  +RL GL   V+          V    H W  Y+SP I++ +YY   +       K  +S P      E  K +  +          L P+ +A + T           GE      P+  LD+     +T+     S +R  Q P    L + +  SPL             + +  +  S+V   IAMM WS+ Y SW++F+LLL AC +W +    +  +  SP I+ Y   L  ++Y++   L ELP    T  G  V L ++G      P   L  M+ +L+ FWL LR F+ + LL   K    L +      + AD+E         + + +   + GI  KYWI VC    + VS    +VV++IVYM L +  L  F   Y+ WRK + VFWW V+ Y+++VL+ +YT+QF  FP  W+N TG ++E L D+GL+ +  S+LF  +L P  FL+  I+Q+ YFH+PF++L+ +                           + +  EV         GP +       ++S    V+  + D+ ++F  ++ +++ F       V R  E H  K+V    V   + E +  N++L++L     P+ +   +    S  W  + ++ KM+YQLK VN   +S+NC+        L     N+S+     +D A W G+ K    +   Q+H+     ++    ++   ++++RQ  + P   +     +  + T Q +D  L++  K+ INF FYK GLE+ F++ V V   R++   +++   L+  L  +R+   +++W  Y LFL + L  +Y +C+G+PP LC  YP        +   L +WL+LP +   P++  +++DF   +  + Q++VF  E +       G         R  P   N +P     +F+  + SY+D LK A+F + +WL L +VF  G   I++F LGY++  F  L  G  ++ +     +  W+ +I YN  VI+SK  L L+ C +++ M S  FCW+I LF + C     +D + M+  +R    P    ++G+ WD  CF F++LQR+IF++  F HV  DL      ASRG  L N   + SI   +  EE
Sbjct:  212 IVLLALAGIAHPSAFSSIYLVVFLAICTWWSCHFPLSPLGFNTLCVMVSCFGAGHLICLYCYQTPFIQDMLPPGNIWARLFGLKNFVDLPNYSSPNALVLNTKHAWPIYVSPGILLLLYYTATS-----LLKLHKSCP-----SELRKETPREDEEHELELDHLEPEPQARDAT----------QGEMPMTTEPD--LDNCTVHVLTSQ----SPVR--QRPVRPRLAELKEMSPLH-----------GLGHLIMDQSYVCALIAMMVWSIMYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGLTLCCLRYVWAMELPELP----TTLGP-VSLHQLGLEHTRYPCLDLGAMLLYLLTFWLLLRQFVKEKLLKKQKVPAALLEV-----TVADTEP---TQTQTLLRSLGELVTGIYVKYWIYVCAGMFIVVSFAGRLVVYKIVYMFLFLLCLTLFQVYYTLWRKLLRVFWWLVVAYTMLVLIAVYTFQFQDFPTYWRNLTGFTDEQLGDLGLEQFSVSELFSSILIPGFFLLACILQLHYFHRPFMQLTDLEHVPPPGTRHPRWAHRQDAVSEAPLLEHQEEEEVFREDGQSMDGPHQATQVPEGTASKWGLVADRLLDLAASFSAVLTRIQVF-------VRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCIIIVCKMLYQLKIVNPHEYSSNCTEPFPNNTNLQPLEINQSLLYRGPVDPANWFGVRKGYPNLGYIQNHLQILLLLVFEAVVYRRQEHYRRQHQQAPLPAQ----AVCADGTRQRLDQDLLSCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFMVILHGCWLVAILTRRRREAIARLWPNYCLFLTLFLLYQYLLCLGMPPALCIDYPWRWSKAIPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGINTDHLEPLRGEP---NPIP-----NFIHCR-SYLDMLKVAVFRYLFWLVLVVVFVAGATRISIFGLGYLLACFYLLLFGTTLLQKDTRAQLVLWDCLILYNVTVIISKNMLSLLSCVFVEQMQSN-FCWVIQLFSLVCTVKGYYDPKEMMTRDRDCLLPVE--EAGIIWDSICFFFLLLQRRIFLSHYFLHVSADLKATALQASRGFALYNAANLKSINFHRQIEE 1339

HSP 2 Score: 382.489 bits (981), Expect = 4.202e-105
Identity = 224/606 (36.96%), Postives = 350/606 (57.76%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKL-RSTESLKINMQAICERRSSDSKTTEKM-VRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLK-DHNQTYLNLTLSMKKENEA----------------RWW--EIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            ++RF+  + + K+    DVY  MFL + +  +IIIFG+ +FG  + + D A   +  +++P  F+ M++ QF  ++IDRAL+LRK V GK  FQ+  V+ IH W+FF LP +T++ F+     QL YFVKCIYFALSAYQ++ GYP RILGNFLT+ +N++NLFLF+G+ +VPFL ELR VMDW+WTDT+++L +WM VED++  IF++KC R +E +YP  +G  ++   KY +GGL++ F     W PL   S I +   V N PI+ T ++ +GGY PLF   +++ ++       ++++ + +  +     ++  +   D+    I+GSS  +W I+PPS  ++K +L   T  + +      +R  +   T E    +HT     +   ++ L + +E      VV I  +FP+++ A     +     L+ D  + YL + + +++E                    WW  E+Q+              K   + L + IFS++VS    G L + YGI+G+Y + + V  + +R F+S+IS+ I  EELP VDRIL L  +I+LVRE +   LEE+L AKLIFLYRS ETMIKWTR  +
Sbjct: 1958 LQRFFHDILHTKYRAATDVYALMFLADIVDIIIIIFGFWAFGKHSAATDIASS-LSDDQVPQAFLFMLLVQFGTMVIDRALYLRKTVLGKLAFQVVLVVAIHIWMFFILPAVTERMFSQNAVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLIRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIVPFTPQAYEELSQQFDPYPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKQELYNGTADITLRFTWNFQRDLAKGGTVEYTNEKHTLELAPNSTARRQLAQLLEGRPDQSVV-IPHLFPKYIRAPNGPEANPVKQLQPDEEEDYLGVRIQLRREQVGTGASGEQAGTKASDFLEWWVIELQDC-------------KADCNLLPMVIFSDKVSPPSLGFL-AGYGIVGLYVSIVLVVGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTRERE 2547

HSP 3 Score: 114.39 bits (285), Expect = 1.372e-23
Identity = 76/229 (33.19%), Postives = 122/229 (53.28%), Query Frame = 2 
Query: 5501 KISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXXXXXXXXXLLAISLG-NVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRV---DPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTE--FAQD-LEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPI 6166
            +    + G  EL A     +   S   ++ +     L+E E   ++    L  +  G      +SE +CYF++ILNHM++ +  SL  P++VFLWAML++PRPSK FW+  I +TE+++V KY+FQF F  +N     R     P + P I+G+EK+ +Y   DL+QL+ +F HR  L   GLW DH E  + +D      K+++ + + ++  E  S T       P+
Sbjct: 1623 QAGTSLHGSQELLANARTRMRTASELLLDRRLHIPELEEAERFEAQQGRTLRLLRAGYQCVAAHSELLCYFIIILNHMVTASAASLVLPVLVFLWAMLTIPRPSKRFWMTAIVFTEVMVVTKYLFQFGFFPWNSYVVLRRYENKPYFPPRILGLEKTDSYIKYDLVQLMALFFHRSQLLCYGLW-DHEEDRYPKDHCRSSVKDREAKEEPEAKLESQSETGTGHPKEPV 1850
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. TrEMBL
Match: A0A4Z2DRN6 (Piezo-type mechanosensitive ion channel component OS=Schistosoma japonicum OX=6182 GN=EWB00_009369 PE=3 SV=1)

HSP 1 Score: 1117.45 bits (2889), Expect = 0.000e+0
Identity = 683/1590 (42.96%), Postives = 926/1590 (58.24%), Query Frame = 2 
Query:  122 DYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLV--------CPFIRYNRXXXXXXXXXXXXXXXTVSGLFSLSISLFHIPLIFNPLF---LSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFY-THRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRV--RSYKEDIKMSSLKQSNEHDP----ELQLIPDKEAVNQ--------------TGSLLTSSVSK----HGEYQTIFR-------------PNQTL--DSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRI----KSPLLIP--TPTERP----------------------------------------------LLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTL---LNASKQNEIL--NDS--------------------KFDQSSNADS-----------------------------EAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLY-----GDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-LTSLKE--NLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELN--EHYLVVRSGDKYLF 4384
            D I LR  +P  L   T+ RYNGFSFIYLL LL         CP            +Q++LI+LIT+S +F+LS    HI L   P +   L  C D   SI+ QIG+  L+G+L YR +RLVLPD   L  ++  L+YF    ++  +VP     S         S   H  D L        KR     T+  S ++    + +   N +   S+ +   H   + T   +  Q+K+WRAWA+ SL +   V++  FAGI SPS+ + VYL  FL ICT+WAC N+     FA +RIFLL+YS +HVCL YL Q  F Q +  + +F +RLLGLYY+++TSC+  GE+ F  + R +D L+P I M +YY+   ETRRW +     + +   R+  +D         N HD     E+ +   +E V+               + + LT++VS     HG      R             PNQ++  +     +   +G+E   +     P+   + ++R+    K+  + P   P++RP                                               LLS+  +AIRNS++ T IAMMAW+V Y+SW+SFILLLSAC LW++P SR ACLY SPLIV YA VLI+IQYIYG NL   ELP+   T +   + LSE+G  +     G LA+ + FLV FWLTLRLF+ +     L A  Q  ++   DS                    KF +  N D+                              A FG +DN IY++   F++ +C KYWI+VCC +ML VS+Q+PVV+FRIVYM++LVYF++ F  SY+ WR+QM  FWW ++VYS+ +LLCIYTYQFN+ P  W+NK  LS EIL+  GL+T+E++ LF+ LLTPVVFLVVII+QV YFH PFLK S++NRF       G         DN N +TS S +SN+S FIEDVNSAFQI++ KL  +   +    WRF E H+ K+V   +V  C NE +A NI+ +I +VI FPF  LH  + T  F W S+ +L KM +QL  ++  N S++C      F  S    D  KW+G +KV+NF+ +I  + A+LVV  +WH V Y QRQFY     T+P  G +FP  T+ S+   L+N+ KF  N+ FYK GLEL   VTV+  C RVD +S++YL+L+L+FL + R++C+++W  YM+ L VL+PI+YA C+GLPPGLC  YP  T   E  NL +WL+LPS    PS  K+ ADFFQF  VALQ+RVF IE       YGGG NRPIL NELP   D+DFVSTK+SY+DY++H IFYWSYW+SLA+V  TGV WITLFCLGYMIL+FIYLWMG N++LR+R++LI SWNVII YNF VIL+KC+LQL+GC Y   M S   CW+I LFGVQC+NP+SW  N   +   H   C++V SGLHWD+ CF+FI+ QRK+F + +F HV+LDL VQ+RFASRGAYLINRK+M +I EQ ++E+  L K++ K++ I QRQ   G+   N  EHY+++RSGD YLF
Sbjct:    7 DLIFLRFTIPFVLFIVTVVRYNGFSFIYLLFLLACPLLEPPKCP-------RSTTKVQVYLILLITLSCVFTLSHPTLHIVLTVAPPYENALRTCQD--ASIAAQIGVQRLEGMLPYRAMRLVLPDIFVLSVAVTSLVYF----SRRRRVPSTLLSSPNALSAAESSIASHIGDGL--------KR----NTSVPSEIKSNRDDAVRTQNFDVKNSKLLDQTH--FNFTSSWNENQRKLWRAWALDSLRMLTTVLLVCFAGITSPSLPSGVYLLSFLAICTYWACRNEFSPIPFASLRIFLLVYSGLHVCLYYLYQFPFFQAFCKDGSFLARLLGLYYIMHTSCEKPGEIIFPDSFRIVDCLAPPITMLLYYVLVIETRRWLDSHSNVLVQTLFRNNVKDSMFPGELSPNGHDENVDDEINVPNTREPVSHEDSPSLALPFTDSCSSTKLTTAVSALPNDHGNEDLTLRSQSDLDNHDSELHPNQSVIQEHSLLKECAAIGHEKYPLSHDTRPTKEEILEERVSHIPKALAIFPHQVPSKRPQQENNYDEQFLSSPVEPHFDALFGLTPPFATYMYGWSRNNVATERPFLLSLHYSAIRNSYILTLIAMMAWAVVYRSWLSFILLLSACILWIVPKSRAACLYSSPLIVLYAIVLILIQYIYGLNLNSDELPQ---TVTPDGLQLSELGMQRSDHCVGALALQMGFLVCFWLTLRLFVMERAARQLTARHQQTVVEHQDSQMHSGSTTLPNFQKSLPTILKFRKRRNKDNGNNLLLTPFSNIVNSFQTHAGYNAGIYGPAASFGTIDNTIYRRFTDFMHSMCVKYWIVVCCLSMLLVSVQQPVVIFRIVYMVMLVYFMLIFQISYAIWRRQMLCFWWVIVVYSMAMLLCIYTYQFNESPNFWQNKLHLSPEILKAFGLETFESAALFERLLTPVVFLVVIILQVHYFHIPFLKASALNRFQLPQVSRGSVHSRSGVSDNHNSNTSISVSSNMSNFIEDVNSAFQIVVSKLYCWAVSLSNHCWRFLEIHWIKVVGLVVVLTCTNEVSAANIISLIFLVICFPFPYLHGFMTTFVFIWTSIQILCKMTFQLSAID-LNISSSC----LKFQNSTTP-DPTKWLGFKKVDNFRQYIMPYCALLVVSVIWHAVAYRQRQFYNNDRNTRPAEGTVFPGVTINSMGYDLLNVVKFAFNYGFYKFGLELCHCVTVVTTCARVDAFSVLYLMLMLVFLFSPRQVCARLWPSYMVILAVLIPIQYASCIGLPPGLCLSYPWFTESVEINNLLQWLYLPSDFGAPSPYKLSADFFQFAAVALQFRVFKIEQRSDSEIYGGGSNRPILTNELPNEGDRDFVSTKESYLDYMRHLIFYWSYWVSLAVVLVTGVVWITLFCLGYMILSFIYLWMGLNVLLRERTSLINSWNVIIGYNFCVILAKCSLQLMGCVYRSRMFSH--CWLIQLFGVQCMNPLSW--NHFNLPPGHETSCATVSSGLHWDIICFIFILFQRKVFTSHSFSHVLLDLQVQSRFASRGAYLINRKLMLAIHEQAMEEKHNLAKVQQKLNLIQQRQEAFGRSNANITEHYIMLRSGDYYLF 1556

HSP 2 Score: 893.264 bits (2307), Expect = 0.000e+0
Identity = 495/999 (49.55%), Postives = 650/999 (65.07%), Query Frame = 2 
Query: 5333 ESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSK--ISNEVDGRIELEAIVVEIVG----------DGSHSFVNSKNQ-------------------------EEYLKEQEXXXXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQDG---------------------RNKIKSS------------------YEESS----PTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTES-LKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSY------------------------------VVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEAR--WWEIQEIVAGETYCSNEKIPKQSHSN----------LTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEK 7951
            ESCWSKFKAS LI Y F  ++ D+LI  +N  T++YRRIRRT+D EKRLVK +V+S    +NE   R++LEA V+EI+              H   N +N                          +++ +E+ FR+SRS  FLL I++GN+AI+YSE  CYFLLI NHM S +L SLPYPLMV LW MLSVPRP+K FWI LITYTEIVIVIKYIFQF F  FN+ T    +  + LW+P I+GI K+ +YA+ DL+QL+ +FLHRGYLKNNGLWRD+TEF  DLE++ +E                         NK+K+                   Y +SS    PT+   + NP+ K++RFY KMT+P++NKKVDVY++MFLCEFIAF II+FGYVSFGP T   DNAF+F+K+N+IP PFI+M++ QF+FIIIDR LFL+KQV GKFIFQI HV+LIH WLFF LPHIT+  F S +APQLLY +KC+YF+LSAYQ++SGYP RILGNFLT+++NYINL LFKGY+++PFLYELRNVMDWMWT ++++L+HWME+EDV+ KIF+LKCWRRSEL YPT RG  R ++ K   GGLLL FFFICFWGP+ L+SFIG TF  NPP+ CTFS S GG+ P F F SRE N+ ++     +    C++       +L +FE  D+  ++IDG S ++W ITPPS + L +KLRS +S L ++    C R + + +++   V    +++L   +K  LL  + +  S +                               V ++A+ PR++   K  L  A A L +  QTY+N++  M ++  +R  WWE++E     +  S+       H            L++  F+ERVSD+LFG +F+NYGIIGMYAAYIF+A R+LR  YS+ISY+IR EELPHVDRILNL +EIYLVREN +  LEEQL+AKL FLYRS+ETMIKWTRH K I+ +   K
Sbjct: 2238 ESCWSKFKASCLIAYMFFLSSVDSLIRFLNGLTRQYRRIRRTIDQEKRLVKRRVISNNPFTNE-QSRVQLEAAVLEIISTTPERQLSLLSPQHIETNPQNNVKRSSEASDYLIHHNSLDNFDNTDLQDHEREKAFRQSRSYGFLLLIAVGNLAIVYSELFCYFLLIFNHMRSSSLLSLPYPLMVLLWGMLSVPRPTKTFWIFLITYTEIVIVIKYIFQFKFFHFNDATLRPIESAEALWLPRILGINKNDDYAVFDLVQLISLFLHRGYLKNNGLWRDYTEFTHDLELIVQENKAVELSHSKQAICSRPLASSCIYLNKLKTDVDKDDGLYSSVHNTFVQQYPQSSHFPVPTTGGKTWNPLVKLKRFYLKMTDPRYNKKVDVYIYMFLCEFIAFWIILFGYVSFGPSTGMGDNAFEFLKSNRIPFPFISMLLVQFIFIIIDRGLFLQKQVLGKFIFQIIHVVLIHGWLFFILPHITRSPFTSGLAPQLLYLIKCVYFSLSAYQIRSGYPRRILGNFLTKNYNYINLVLFKGYLLLPFLYELRNVMDWMWTSSALSLYHWMELEDVYSKIFILKCWRRSELAYPTPRGQNRDISKKALTGGLLLLFFFICFWGPMALTSFIGATFDVNPPVLCTFSFSFGGFPPTFEFTSREGNIFTVNASELNNFIRCHEKDKQTFGFLHNFEWNDLRYVTIDGFSGNIWAITPPSYQALLMKLRSADSDLLLHFHMKCRRSTKEIQSSHTSVEDIFSRKLSPLEKLQLLMVLNSTNSIFPSSDYKRNTTYTTFINNDNMSTMSHQSRIDSVTLNAVLPRYVLLKKDKLRGAYAFLGN-PQTYVNVSFHMHQDLTSRQAWWELKE-KTNNSPTSDPCFEVIRHPTLSINAIEANVLSILTFNERVSDSLFGKVFNNYGIIGMYAAYIFLASRLLRTMYSNISYVIRLEELPHVDRILNLCHEIYLVRENNLLLLEEQLVAKLFFLYRSSETMIKWTRHPKHIVERFTSK 3233
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. TrEMBL
Match: A0A419QG60 (Piezo-type mechanosensitive ion channel component OS=Clonorchis sinensis OX=79923 GN=PIEZO2 PE=3 SV=1)

HSP 1 Score: 957.207 bits (2473), Expect = 0.000e+0
Identity = 508/969 (52.43%), Postives = 664/969 (68.52%), Query Frame = 2 
Query: 1565 TERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTD---------------TLLNASKQNEILNDSKFDQSSNA--DSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRF--LYG--DSREVGPFEDNLNIXXXXXXXXNVSA-FIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-LTSLKE--NLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGK--PELNEHYLVVRSGDKYLF 4384
            TERPLLLS+  +AIR+S++ T IAMMAW+VTY+SW+SFILLLSAC +W+ P+SR ACLY SP+IV YA VLI+IQYIYG NLT  ELP+   T  G  ++++E+G  KW I  G L + I+FLV FWLTLRLF+ +               ++ +   +   + D     S  +   S   FG VDN  Y++    L  +C KYWI+VCC +ML +SIQ+PVV+FRI YM++L YF+  F  SY FWR+QM  FWW  +VYS+ +LLCIYTYQF   P  W+  TGLSEE+L+DIGL+T++++ LF  LLTPV+FLVVII+QV YFH+PFLK S+++RF  +Y   D     P +   + +T S ST++  + FIEDVNSAF  I+ KL  +   +    WRF E H+ K+V   I+   +NE  A NI+ ++L+VI FPF  LH  L T  F W  L  L KM +QL  V       N ++   + NK+   ++NA W GL KV NF  +I    A++ VC  WH + Y Q+QFY  P+  +P  G++FP+ T+ S+D+ L N+ KF IN+ FYK GLEL F VTV+ ACLR D +S++YL+L+L FL T R++C K+WLPYM+FL  L+P++YA CVG PPGLC  YP LT   +  NL +WLF+P     P+AKK+ ADFFQFV VALQY+VF IE   +V  YGGG N+P+L N +P   ++DFVS K+SY+DYL+H IFYWSYW+SLAIV  TGV WITLFCLGYMIL+FIYLWMGQN+MLRKRS+LI SWNVII YNF VIL+KC+LQ++GC Y  W      CW I LFGVQC++PMSW R    V   +   C +V SGLHWDV CF+FI+ QRK+FMT++F HVV DLNVQ++FASRGAYLINRK+M  I EQ  +EE +L KI+ K+  I +RQA  G+    + EHY+++RSGD YLF
Sbjct:  545 TERPLLLSLHFSAIRHSYIVTLIAMMAWAVTYRSWLSFILLLSACIMWISPNSRAACLYASPVIVLYAIVLILIQYIYGLNLTTAELPQ-QVTPDG--LEMAELGMKKWEISVGALGLQITFLVFFWLTLRLFVNERSYRRYATRSPTGYPSVGHFVGRGTSIWDRHLATSFGSWFGSTFAFGTVDNTAYRRFTELLRALCVKYWIVVCCLSMLLISIQQPVVIFRIFYMVMLTYFMFFFQVSYGFWRRQMIFFWWINVVYSMAILLCIYTYQFRNSPEFWQRTTGLSEEVLKDIGLETFDSAALFARLLTPVLFLVVIILQVHYFHEPFLKRSALDRFNRMYELRDLASTTPQQSADHAATLSPSTTSSLSNFIEDVNSAFHTIVTKLIAWAISLTNCCWRFMEVHWIKVVALLILLNAVNEVVAPNIITLVLLVICFPFPYLHGFLATIVFVWTGLLTLCKMCFQLNFVQ-----LNVTIVCADSNKTT-HLENASWAGLIKVQNFNHYILPMGALMFVCVFWHAISYRQKQFYNSPHNLRPHEGVVFPDVTMASLDNDLRNVVKFAINYGFYKFGLELCFCVTVVTACLRADAFSVLYLLLMLFFLFTPRQVCGKLWLPYMIFLAALIPVQYAGCVGFPPGLCWNYPWLTDSVDVNNLLQWLFVPGQYGSPTAKKLTADFFQFVAVALQYQVFKIEKRFSVKEYGGGSNKPVLINNVPGKDERDFVSAKESYLDYLRHLIFYWSYWVSLAIVLATGVTWITLFCLGYMILSFIYLWMGQNVMLRKRSSLIKSWNVIIGYNFCVILAKCSLQVVGCVY--WARMSHQCWFIQLFGVQCMDPMSWSRFEPPV---YDKQCETVSSGLHWDVICFIFILFQRKVFMTQSFSHVVFDLNVQSQFASRGAYLINRKLMTDISEQLAREELLLAKIREKLAVIQRRQAVLGRNTDNITEHYIMIRSGDYYLF 1499

HSP 2 Score: 857.055 bits (2213), Expect = 0.000e+0
Identity = 433/828 (52.29%), Postives = 570/828 (68.84%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIV-----------DKEQDGRNKIKSSYEESSP------------TSNKWSC---------NPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTES-LKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQ-----------------SSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKE--NEARWWEIQE--IVAGETYCSNEKIPKQSHS---NLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKT 7954
            LL I+LGN+AI+YSE+ CY LL++NHM S N+ SL YPL+VFLW MLSVPRP+K FWI LITYTE+VIVIKYIFQF FI+FN+ +    D  + LWIP ++G+EKS +YAI DL+QL+ +FLHRG+LKN+GLWRDHTEF QDL++V           + EQ G + ++    ES+             TS + +          NP  K+RRFY KMT+P+FNKKVDVY++MFLCEFI+F II+ GYVSFGP T   DNAF+FI++N++P PF+ M++ QF+FII+DR LFLRKQV GKFIFQI HVLLIH WLFF LPHITK  F +  APQLLY +KC+YF+LSAYQ++SGYPLRILGNFLT+ +NYINL LFKGY+I+PFLYELRN+MDWMWT+++++L+HWME+EDV+ KIFV KCWRRSE+ YPT RG  R    K  VGGL+LAFFF C W PL LSSFIG TFV NPP+ CTFS+S+GG+ P+F F SRE N+  + +   D    C++       +L +FE  D+  I+IDG S ++W ITPPS + L  KL    S L ++    C R++ + +T++  V    +++L   +K  L   +                     SS  V ++A+ PR+L   +  L  A A L   + TY+N++  + ++      WWE++E  I + +      + P    S    L++  F+ERVSD+LFG  F  YGI+GMY AY+F+ +R+ R  Y++ISY+IR EELPHVDRILNL NEIYLVRENK+ RLEEQL+AKL FLYRS+ETMIKWTRH K I+ +  +++
Sbjct: 2448 LLLIALGNMAIVYSEWFCYLLLVVNHMRSSNILSLVYPLVVFLWGMLSVPRPTKTFWIFLITYTEVVIVIKYIFQFRFITFNDPSLKPADSAEALWIPRLLGVEKSGHYAIFDLVQLISLFLHRGFLKNDGLWRDHTEFVQDLQLVAERNKVAERVQNGEQVGPDFLRLLSTESAASQMTERHNVDGVTSGRLTVSRRDALHTWNPFAKLRRFYHKMTDPQFNKKVDVYIYMFLCEFISFWIIMLGYVSFGPSTGMGDNAFEFIRSNRVPFPFVCMLLVQFIFIIVDRGLFLRKQVLGKFIFQILHVLLIHGWLFFILPHITKSPFTAGFAPQLLYLIKCVYFSLSAYQIRSGYPLRILGNFLTKKYNYINLILFKGYLIIPFLYELRNIMDWMWTNSTLSLYHWMELEDVYAKIFVHKCWRRSEIAYPTPRGVNRPAGKKALVGGLILAFFFACLWIPLALSSFIGATFVFNPPVLCTFSLSIGGFPPVFEFTSREGNILKIRQQDLDSFTRCHEKDLQTVGFLNNFEVDDLRYITIDGFSGNIWAITPPSYDTLVKKLSDASSDLLLHSHMQCRRKTKEIQTSQISVEDIFSRKLQPLEKIELYGVLNTTAVGSAYNNTQVKPSSRVISSSPVTLNAVMPRYLVLKRDRLRPAYATLGLES-TYINVSFVIHRDPAKNQSWWELKERAITSSDACFEKLRFPTLGDSWADALSIMTFNERVSDSLFGKWFFTYGILGMYGAYLFLVNRLFRTVYTNISYVIRLEELPHVDRILNLCNEIYLVRENKLLRLEEQLVAKLFFLYRSSETMIKWTRHPKRIIDQFTDRS 3274

HSP 3 Score: 173.326 bits (438), Expect = 6.327e-39
Identity = 124/417 (29.74%), Postives = 205/417 (49.16%), Query Frame = 2 
Query:  293 TVSGLFSLSISLFHIPLIFNPLF---LSNC-------------TDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQS-RKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVP---RVRSYKEDIKMS-SLKQSNEHDPE-LQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGN 1474
            T+S +F+LS    HI L   P +   L  C               + ++I+ QIG+  L GVL YR +RLVLPD   L  ++ LL+Y  +            ++      N  +S  G++P                    E +   + S  +L+ N++  +    K   +   L      D  ++K+WRAWA+ +  V  +V++    GI SPS+ +++YL  FLGI T+WAC + +    FA +RIFLL+YS +HVCL YL Q  F Q   P N F++RLLGLYY++ T+C   GE+ F    R +D++ P + +++YY+ A ET RW E   +       VR+    ++ S ++ +   H  E   L+P  E    + S  T++V  + +  ++   N+T  ++ + D+  +G+
Sbjct:   37 TLSCVFTLSHPTLHIILAVAPPYDDALKTCRSLYNERIHIHLRVGEESTIAAQIGVQRLNGVLPYRAMRLVLPDIFILAIAVGLLVYVSRRGHGG------SRRQASVTRNAAVSGQGYSP--------------APRDINERALAPYASPPVLANNSSSANPLFGKFTSSMAGLPFPRAWDENRRKLWRAWAVDNFCVLLSVLLVCVTGITSPSVPSAIYLLSFLGIGTYWACRSGMNPVPFACLRIFLLVYSGLHVCLYYLYQFPFFQSICPANGFTARLLGLYYIMQTTCDKPGEIIFPVDVRIVDFIVPPLTIFLYYVLAFETWRWLESSHKRSTLFHNVRNANTPVRTSPAVVEETGHPLEYANLLPLDEVPASSES--TNTVKINNKTPSVSLANET--AQVSPDVHPIGS 429
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. TrEMBL
Match: A0A4S2LHK5 (Piezo-type mechanosensitive ion channel component OS=Opisthorchis felineus OX=147828 GN=CRM22_007115 PE=3 SV=1)

HSP 1 Score: 953.355 bits (2463), Expect = 0.000e+0
Identity = 506/969 (52.22%), Postives = 665/969 (68.63%), Query Frame = 2 
Query: 1565 TERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTD------TLLNASKQNEI-----LNDSKFDQSSNADSEAYFGN------VDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRF--LYG--DSREVGPFEDNLNIXXXXXXXXNVSA-FIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-LTSLKE--NLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGK--PELNEHYLVVRSGDKYLF 4384
             ERPLLLS+  +AIR+S++ T IAMMAW+VTY+SW+SFILLLSAC +W+ P+SR ACLY SPLIV YA VLI+IQY+YG NLT  ELP+   T  G  ++++E+G  KW    G L + I+FLV FWLTLRLF+ +      T  + +    +        S +D+      E++FG+      VDN  Y++    L  +C KYWI+VCC +ML +SIQ+PVV+FRI YM++L+YF+  F  SY FWR+QM  FWW  +VYS+ +LLCIYTYQF   P  W+  TGLSEE+L+DIGL+T++++ LF  LLTPV+FLVVII+QV YFH+PFLK S+++RF  LY   D     P +   + +T S ST++  + FIEDVNSAF  I+ KL  +   +    WRF E H+ K+V   I+   +NE  A NI+ ++L+VI FPF  LH  L T  F W  L  L KM +QL  V       N ++   + NK+   ++NA W GL KV NF  +I    A++ VC  WH + Y Q+QFY  P+  +P  G++FP+ T+ S+D+ L N+ KF IN+ FYK GLEL F VTV+ ACLR D +S++YL+L+L FL T R++C K+WLPYM+FL  L+P++YA CVG PPG+C  YP LT   +  NL +WLF+P     P+AKK+ ADFFQFV VALQY+VF IE   +V  YGGG N+P+L N +P   ++DFVS K+SY+DYL+H IFYWSYW+SLAIV  TGV WITLFCLGYMIL+FIYLWMGQN+MLR+RS+LI SWNVII YNF VIL+KC+LQ++GC Y  W      CW I LFGVQC++PMSW R    V   +   C +V SGLHWDV CF+FI+ QRK+FMT++F HVV DLNVQ++FASRGAYLINRK+M  I EQ  +EE  L KI+ K+  I +RQA  G+    + EHY+++RSGD YLF
Sbjct:  556 AERPLLLSLHFSAIRHSYIVTLIAMMAWAVTYRSWLSFILLLSACIVWISPNSRAACLYASPLIVLYAIVLILIQYVYGLNLTTAELPK-QVTPDG--LEMAELGMKKWDNSVGALGLQITFLVFFWLTLRLFVNERSYRRFTTRSPTGYPSVGHPIGRGTSIWDRHLATSVESWFGSTFAFGTVDNTAYRRFTELLRALCVKYWIVVCCLSMLLISIQQPVVIFRIFYMVMLIYFMFFFQVSYGFWRRQMIFFWWINVVYSMAILLCIYTYQFKNSPEFWQRTTGLSEEVLKDIGLETFDSAALFARLLTPVLFLVVIILQVHYFHEPFLKRSALDRFNRLYELRDLASTTPQQSADHAATLSPSTTSSLSNFIEDVNSAFHTIVTKLIAWAISLTNCCWRFMEVHWIKVVALLILLNAVNEVVAPNIITLVLLVICFPFPYLHGFLATIVFVWTGLFTLCKMCFQLNFVQ-----LNVTIVCADSNKTT-HLENASWAGLVKVQNFNHYILPMGALMFVCVFWHAISYRQKQFYNSPHNLRPHEGVVFPDVTIASLDNDLRNVVKFAINYGFYKFGLELCFCVTVVTACLRADAFSVLYLLLMLFFLFTPRQVCGKLWLPYMIFLAALIPVQYAGCVGFPPGICWNYPWLTDSVDINNLLQWLFVPGQYGSPTAKKLTADFFQFVAVALQYQVFKIEKRFSVKEYGGGSNKPVLINNVPGKEERDFVSAKESYLDYLRHLIFYWSYWVSLAIVLATGVTWITLFCLGYMILSFIYLWMGQNVMLRRRSSLIKSWNVIIGYNFCVILAKCSLQVVGCVY--WARMSHQCWFIQLFGVQCMDPMSWSRFEPPV---YDKQCETVSSGLHWDVICFIFILFQRKVFMTQSFSHVVFDLNVQSQFASRGAYLINRKLMTDISEQLAREELSLAKIREKLAVIQRRQAVLGRNTDNITEHYIMIRSGDYYLF 1510

HSP 2 Score: 899.812 bits (2324), Expect = 0.000e+0
Identity = 493/1012 (48.72%), Postives = 654/1012 (64.62%), Query Frame = 2 
Query: 5177 ESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKPAQKDFEDNLLCVPDPESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVG------DGSHSFVNSKNQE------------EYL--------KEQEXXXXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIV-----------DKEQDGRNKIKSSYEESSP------------TSNKWSC---------NPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTES-LKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQ-----------------SSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKE--NEARWWEIQE--IVAGETYCSNEKIPKQSHS---NLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKT 7954
            E      P +   T  SS S+    S D+       PA +  E         E CWSKFKA  L+ Y F+ ++ D+LI L+N  TK YR IRR ++ EKR VKL V++   +     +++E  V  +V        G   F++ +  +            E+L        +E+ FR+SRSR FLL I+LGN+AI+YSE+ CY LL++NHM S N+ SL YPL+VFLW MLSVPRP+K FWI LITYTE+VIVIKYIFQF FI+FN+ +    D  + LWIP ++G+EKS +YAI DL+QL+ +FLHRG+LKN+GLWRDHTEF QDL++V           + EQ G + ++    ES+             TS + +          NP  K+RRFY KMT+P+FNKKVDVY++MFLCEFI+F II+FGYVSFGP T   DNAF+FI++N++P PF+ M++ QF+FIIIDR LFLRKQV GKFIFQI HVLLIH WLFF LPHITK  F +  APQLLY +KC+YF+LSAYQ++SGYPLRILGNFLT+ +NYINL LFKGY+IVPFLYELRN+MDWMWT+++++L+HWME+EDV+ KIFV KCWRRSE+ YPT RG  R    K  VGGL+LAFFF C W PL LSSFIG TFV NPP+ CTFS+S+GG+ P+F F SRE N+  + +   D    C++       +L +FE  D+  I+IDG S ++W ITPPS + L  KL    S L ++    C R++ + +T++  V    +++L   +K  L   +                     SS  V ++A+ PR+L   +  L  A A L   N TY+N++  + ++      WWE++E  I + +      + P    S    L++  F+ERVSD+LFG  F  YGI+GMY AY+F+ +R+ R  Y++ISY+IR EELPHVDRILNL NEIYLVRENK+ RLEEQL+AKL FLYRS+ETMIKWTRH K I+ +  +++
Sbjct: 2173 EKRAAGKPAMLAFTRSSSKSLDNPDSEDQLGDDSNTPAAQQRE---------EGCWSKFKAFCLVTYLFLLSSVDSLIYLLNGLTKHYRNIRRRIEREKRCVKLNVINNTQHPEQSPLDIEVAVFNVVSKSPEHVSGGVPFLDPQISDRCRAALVPGQSIEHLDALDRHQQREKAFRQSRSRPFLLLIALGNMAIVYSEWFCYLLLVVNHMRSSNILSLVYPLVVFLWGMLSVPRPTKTFWIFLITYTEVVIVIKYIFQFRFITFNDPSLKPADSAEALWIPRLLGVEKSGHYAIFDLVQLISLFLHRGFLKNDGLWRDHTEFVQDLQLVAERNKVAERVQNGEQVGPDFLRLLSTESAASQMVEGHNVDAVTSGRLTVSRRDALHTWNPFAKLRRFYHKMTDPQFNKKVDVYIYMFLCEFISFWIIMFGYVSFGPSTGMGDNAFEFIRSNRVPFPFVCMLLVQFIFIIIDRGLFLRKQVLGKFIFQILHVLLIHGWLFFILPHITKSPFTAGFAPQLLYLIKCVYFSLSAYQIRSGYPLRILGNFLTKKYNYINLILFKGYLIVPFLYELRNIMDWMWTNSTLSLYHWMELEDVYAKIFVHKCWRRSEIAYPTPRGVNRPAGKKALVGGLILAFFFACLWIPLALSSFIGATFVFNPPVLCTFSLSIGGFPPVFEFTSREGNILKIRQQDLDSFTRCHEKDLQTVGFLNNFEVDDLRYITIDGFSGNIWAITPPSYDTLVKKLSDASSDLLLHSHMQCRRKTKEIQTSQISVEDIFSRKLQPLEKIELYDVLNTTAVGSAANNTQVKLSSRVLSSSPVTLNAVMPRYLVLKRDRLRPAYATLGREN-TYINVSFVIHRDPAKNQSWWELKERAITSSDACFEKLRFPTLGDSWADALSIMTFNERVSDSLFGKWFFTYGILGMYGAYLFLVNRLFRTVYTNISYVIRLEELPHVDRILNLCNEIYLVRENKLLRLEEQLVAKLFFLYRSSETMIKWTRHPKRIIDQFTDRS 3174

HSP 3 Score: 211.075 bits (536), Expect = 2.348e-50
Identity = 143/404 (35.40%), Postives = 222/404 (54.95%), Query Frame = 2 
Query:  113 VTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFI-RYNRXXXXXXXXXXXXXXXTVSGLFSLSISLFHIPLIFNPLF---LSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQS-RKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKG--RESVPR-VRSYKEDIKMSSL 1297
             + D +LLR  L   L   T+ RYNGFSF+YL+ LL CP + + N  H +  IQ+FLI+L+T+S +F+LS    HI L   P +   L  C +  ++I+ QIG+  L GVL YR +RLVLPD   L  ++ LL+Y  +            ++      N  +S  G++P                   +E +   + S  +++ N++  +    K   +   L      D  ++K+WRAWA+ +L V  +V++    GI SPS+ ++VYL  FLGI T+WAC + +    FA +RIFLL+YS +HVCL YL Q  F Q   P N F++RLLGLYY++ T+C   GE+ F    R +D+++P + +++YY+ A ET RW E    R ++ R VR+    +++S +
Sbjct:    2 ASLDTVLLRVVLVTTLFLVTVVRYNGFSFVYLVFLLACPLLPQPNSSHSKTKIQVFLILLVTLSCVFTLSHPTLHIILAVAPPYDDALKTCEE--STIAAQIGVQRLNGVLPYRAMRLVLPDIFILAIAVGLLVYVSRRGHGG------SRRQASVTRNVAVSGQGYSP--------------APRGMSERTLAPYASPPVVANNSSSANPFFGKFTSSMAALPFPRAWDENRRKLWRAWAVDNLCVLLSVLLVCVTGITSPSVPSAVYLLSFLGIGTYWACRSGMNPVPFACLRIFLLVYSGLHVCLYYLYQFPFFQSICPANGFTARLLGLYYIMQTTCDKPGEILFPIDVRIVDFIAPPLTIFLYYVLAFETWRWLESSNRRSTLFRNVRNASTPVRISPV 383
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. TrEMBL
Match: A0A4S2LHI2 (Piezo-type mechanosensitive ion channel component OS=Opisthorchis felineus OX=147828 GN=CRM22_007115 PE=3 SV=1)

HSP 1 Score: 953.355 bits (2463), Expect = 0.000e+0
Identity = 506/969 (52.22%), Postives = 665/969 (68.63%), Query Frame = 2 
Query: 1565 TERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTD------TLLNASKQNEI-----LNDSKFDQSSNADSEAYFGN------VDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRF--LYG--DSREVGPFEDNLNIXXXXXXXXNVSA-FIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-LTSLKE--NLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGK--PELNEHYLVVRSGDKYLF 4384
             ERPLLLS+  +AIR+S++ T IAMMAW+VTY+SW+SFILLLSAC +W+ P+SR ACLY SPLIV YA VLI+IQY+YG NLT  ELP+   T  G  ++++E+G  KW    G L + I+FLV FWLTLRLF+ +      T  + +    +        S +D+      E++FG+      VDN  Y++    L  +C KYWI+VCC +ML +SIQ+PVV+FRI YM++L+YF+  F  SY FWR+QM  FWW  +VYS+ +LLCIYTYQF   P  W+  TGLSEE+L+DIGL+T++++ LF  LLTPV+FLVVII+QV YFH+PFLK S+++RF  LY   D     P +   + +T S ST++  + FIEDVNSAF  I+ KL  +   +    WRF E H+ K+V   I+   +NE  A NI+ ++L+VI FPF  LH  L T  F W  L  L KM +QL  V       N ++   + NK+   ++NA W GL KV NF  +I    A++ VC  WH + Y Q+QFY  P+  +P  G++FP+ T+ S+D+ L N+ KF IN+ FYK GLEL F VTV+ ACLR D +S++YL+L+L FL T R++C K+WLPYM+FL  L+P++YA CVG PPG+C  YP LT   +  NL +WLF+P     P+AKK+ ADFFQFV VALQY+VF IE   +V  YGGG N+P+L N +P   ++DFVS K+SY+DYL+H IFYWSYW+SLAIV  TGV WITLFCLGYMIL+FIYLWMGQN+MLR+RS+LI SWNVII YNF VIL+KC+LQ++GC Y  W      CW I LFGVQC++PMSW R    V   +   C +V SGLHWDV CF+FI+ QRK+FMT++F HVV DLNVQ++FASRGAYLINRK+M  I EQ  +EE  L KI+ K+  I +RQA  G+    + EHY+++RSGD YLF
Sbjct:  556 AERPLLLSLHFSAIRHSYIVTLIAMMAWAVTYRSWLSFILLLSACIVWISPNSRAACLYASPLIVLYAIVLILIQYVYGLNLTTAELPK-QVTPDG--LEMAELGMKKWDNSVGALGLQITFLVFFWLTLRLFVNERSYRRFTTRSPTGYPSVGHPIGRGTSIWDRHLATSVESWFGSTFAFGTVDNTAYRRFTELLRALCVKYWIVVCCLSMLLISIQQPVVIFRIFYMVMLIYFMFFFQVSYGFWRRQMIFFWWINVVYSMAILLCIYTYQFKNSPEFWQRTTGLSEEVLKDIGLETFDSAALFARLLTPVLFLVVIILQVHYFHEPFLKRSALDRFNRLYELRDLASTTPQQSADHAATLSPSTTSSLSNFIEDVNSAFHTIVTKLIAWAISLTNCCWRFMEVHWIKVVALLILLNAVNEVVAPNIITLVLLVICFPFPYLHGFLATIVFVWTGLFTLCKMCFQLNFVQ-----LNVTIVCADSNKTT-HLENASWAGLVKVQNFNHYILPMGALMFVCVFWHAISYRQKQFYNSPHNLRPHEGVVFPDVTIASLDNDLRNVVKFAINYGFYKFGLELCFCVTVVTACLRADAFSVLYLLLMLFFLFTPRQVCGKLWLPYMIFLAALIPVQYAGCVGFPPGICWNYPWLTDSVDINNLLQWLFVPGQYGSPTAKKLTADFFQFVAVALQYQVFKIEKRFSVKEYGGGSNKPVLINNVPGKEERDFVSAKESYLDYLRHLIFYWSYWVSLAIVLATGVTWITLFCLGYMILSFIYLWMGQNVMLRRRSSLIKSWNVIIGYNFCVILAKCSLQVVGCVY--WARMSHQCWFIQLFGVQCMDPMSWSRFEPPV---YDKQCETVSSGLHWDVICFIFILFQRKVFMTQSFSHVVFDLNVQSQFASRGAYLINRKLMTDISEQLAREELSLAKIREKLAVIQRRQAVLGRNTDNITEHYIMIRSGDYYLF 1510

HSP 2 Score: 863.603 bits (2230), Expect = 0.000e+0
Identity = 437/828 (52.78%), Postives = 571/828 (68.96%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIV-----------DKEQDGRNKIKSSYEESSP------------TSNKWSC---------NPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTES-LKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQ-----------------SSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKE--NEARWWEIQE--IVAGETYCSNEKIPKQSHS---NLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKT 7954
            LL I+LGN+AI+YSE+ CY LL++NHM S N+ SL YPL+VFLW MLSVPRP+K FWI LITYTE+VIVIKYIFQF FI+FN+ +    D  + LWIP ++G+EKS +YAI DL+QL+ +FLHRG+LKN+GLWRDHTEF QDL++V           + EQ G + ++    ES+             TS + +          NP  K+RRFY KMT+P+FNKKVDVY++MFLCEFI+F II+FGYVSFGP T   DNAF+FI++N++P PF+ M++ QF+FIIIDR LFLRKQV GKFIFQI HVLLIH WLFF LPHITK  F +  APQLLY +KC+YF+LSAYQ++SGYPLRILGNFLT+ +NYINL LFKGY+IVPFLYELRN+MDWMWT+++++L+HWME+EDV+ KIFV KCWRRSE+ YPT RG  R    K  VGGL+LAFFF C W PL LSSFIG TFV NPP+ CTFS+S+GG+ P+F F SRE N+  + +   D    C++       +L +FE  D+  I+IDG S ++W ITPPS + L  KL    S L ++    C R++ + +T++  V    +++L   +K  L   +                     SS  V ++A+ PR+L   +  L  A A L   N TY+N++  + ++      WWE++E  I + +      + P    S    L++  F+ERVSD+LFG  F  YGI+GMY AY+F+ +R+ R  Y++ISY+IR EELPHVDRILNL NEIYLVRENK+ RLEEQL+AKL FLYRS+ETMIKWTRH K I+ +  +++
Sbjct: 2457 LLLIALGNMAIVYSEWFCYLLLVVNHMRSSNILSLVYPLVVFLWGMLSVPRPTKTFWIFLITYTEVVIVIKYIFQFRFITFNDPSLKPADSAEALWIPRLLGVEKSGHYAIFDLVQLISLFLHRGFLKNDGLWRDHTEFVQDLQLVAERNKVAERVQNGEQVGPDFLRLLSTESAASQMVEGHNVDAVTSGRLTVSRRDALHTWNPFAKLRRFYHKMTDPQFNKKVDVYIYMFLCEFISFWIIMFGYVSFGPSTGMGDNAFEFIRSNRVPFPFVCMLLVQFIFIIIDRGLFLRKQVLGKFIFQILHVLLIHGWLFFILPHITKSPFTAGFAPQLLYLIKCVYFSLSAYQIRSGYPLRILGNFLTKKYNYINLILFKGYLIVPFLYELRNIMDWMWTNSTLSLYHWMELEDVYAKIFVHKCWRRSEIAYPTPRGVNRPAGKKALVGGLILAFFFACLWIPLALSSFIGATFVFNPPVLCTFSLSIGGFPPVFEFTSREGNILKIRQQDLDSFTRCHEKDLQTVGFLNNFEVDDLRYITIDGFSGNIWAITPPSYDTLVKKLSDASSDLLLHSHMQCRRKTKEIQTSQISVEDIFSRKLQPLEKIELYDVLNTTAVGSAANNTQVKLSSRVLSSSPVTLNAVMPRYLVLKRDRLRPAYATLGREN-TYINVSFVIHRDPAKNQSWWELKERAITSSDACFEKLRFPTLGDSWADALSIMTFNERVSDSLFGKWFFTYGILGMYGAYLFLVNRLFRTVYTNISYVIRLEELPHVDRILNLCNEIYLVRENKLLRLEEQLVAKLFFLYRSSETMIKWTRHPKRIIDQFTDRS 3283

HSP 3 Score: 211.075 bits (536), Expect = 2.612e-50
Identity = 143/404 (35.40%), Postives = 222/404 (54.95%), Query Frame = 2 
Query:  113 VTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFI-RYNRXXXXXXXXXXXXXXXTVSGLFSLSISLFHIPLIFNPLF---LSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQS-RKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFEKG--RESVPR-VRSYKEDIKMSSL 1297
             + D +LLR  L   L   T+ RYNGFSF+YL+ LL CP + + N  H +  IQ+FLI+L+T+S +F+LS    HI L   P +   L  C +  ++I+ QIG+  L GVL YR +RLVLPD   L  ++ LL+Y  +            ++      N  +S  G++P                   +E +   + S  +++ N++  +    K   +   L      D  ++K+WRAWA+ +L V  +V++    GI SPS+ ++VYL  FLGI T+WAC + +    FA +RIFLL+YS +HVCL YL Q  F Q   P N F++RLLGLYY++ T+C   GE+ F    R +D+++P + +++YY+ A ET RW E    R ++ R VR+    +++S +
Sbjct:    2 ASLDTVLLRVVLVTTLFLVTVVRYNGFSFVYLVFLLACPLLPQPNSSHSKTKIQVFLILLVTLSCVFTLSHPTLHIILAVAPPYDDALKTCEE--STIAAQIGVQRLNGVLPYRAMRLVLPDIFILAIAVGLLVYVSRRGHGG------SRRQASVTRNVAVSGQGYSP--------------APRGMSERTLAPYASPPVVANNSSSANPFFGKFTSSMAALPFPRAWDENRRKLWRAWAVDNLCVLLSVLLVCVTGITSPSVPSAVYLLSFLGIGTYWACRSGMNPVPFACLRIFLLVYSGLHVCLYYLYQFPFFQSICPANGFTARLLGLYYIMQTTCDKPGEILFPIDVRIVDFIAPPLTIFLYYVLAFETWRWLESSNRRSTLFRNVRNASTPVRISPV 383
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. TrEMBL
Match: A0A074ZBD7 (Piezo-type mechanosensitive ion channel component OS=Opisthorchis viverrini OX=6198 GN=T265_07873 PE=3 SV=1)

HSP 1 Score: 951.429 bits (2458), Expect = 0.000e+0
Identity = 504/969 (52.01%), Postives = 660/969 (68.11%), Query Frame = 2 
Query: 1565 TERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT--ELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTD---------------TLLNASKQNEILNDSKFDQSSNA--DSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRF--LYG--DSREVGPFEDNLNIXXXXXXXXNVSA-FIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYP-LTSLKE--NLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGK--PELNEHYLVVRSGDKYLF 4384
             ERPLLLS+  +AIR+S++ T IAMMAW+VTY+SW+SFILLLSAC +W+ P+SR ACLY SP+IV YA VLI+IQY+YG NLT  ELP+   T  G  +++ E+G  KW    G L + I+FLV FWLTLRLF+ +               ++ +   +   +       S  +   S   FG VDN  Y++    L  +C KYWI+VCC +ML +SIQ+PVV+FRI YM++L+YF+  F  SY FWR+QM  FWW  +VYS+ +LLCIYTYQF   P  W+  TGLSEE+L+DIGL+T++++ LF  LLTPV+FLVVII+QV YFH+PFLK S+++RF  LY   D     P +   + +T S ST++  + FIEDVNSAF  I+ KL  +   +    WRF E H+ K+V   I+   +NE  A NI+ ++L+VI FPF  LH  L T  F W  L  L KM +QL  V       N ++   + NK+   ++NA W GL KV NF  +I    A++ VC  WH + Y Q+QFY  P+  +P  G++FP+ T+ S+D+ L N+ KF IN+ FYK GLEL F VTV+ ACLR D +S++YL+L+L FL T R++C K+WLPYM+FL  L+P++YA CVG PPG+C  YP LT   +  NL +WLF+P     P+AKK+ ADFFQFV VALQY+VF IE   +V  YGGG N+P+L N +P   ++DFVS K+SY+DYL+H IFYWSYW+SLAIV  TGV WITLFCLGYMIL+FIYLWMGQN+MLRKRS+LI SWNVII YNF VIL+KC+LQ++GC Y  W      CW I LFGVQC++PMSW R    V   +   C +V SGLHWDV CF+FI+ QRK+FMT++F HVV DLNVQ++FASRGAYLINRK+M  I EQ  +EE  L KI+ K+  I +RQA  G+    + EHY+++RSGD YLF
Sbjct:  556 AERPLLLSLHFSAIRHSYIVTLIAMMAWAVTYRSWLSFILLLSACIMWISPNSRAACLYASPVIVLYAIVLILIQYVYGLNLTTAELPQ-QVTPDG--LEMEELGMKKWENSVGALGLQITFLVFFWLTLRLFVNERSYRRYTTRSPTGYPSVGHLIGRGTSIWGRHLATSVGSWFGSTFAFGTVDNTAYRRFTELLRALCVKYWIVVCCLSMLLISIQQPVVIFRIFYMVMLIYFMFFFQVSYGFWRRQMIFFWWINVVYSMAILLCIYTYQFRNSPEFWQRTTGLSEEVLKDIGLETFDSAALFARLLTPVLFLVVIILQVHYFHEPFLKRSALDRFNRLYELRDLASTTPQQSADHAATLSPSTTSSLSNFIEDVNSAFHTIVTKLIAWATSLTNCCWRFMEVHWIKVVALLILLNAVNEVVAPNIITLVLLVICFPFPYLHGFLATIVFVWTGLLTLCKMCFQLNFVQ-----LNVTVVCADSNKTT-HLENASWAGLIKVQNFNHYILPMGALMFVCVFWHAISYRQKQFYNSPHNLRPHEGVVFPDVTIASLDNDLRNVVKFAINYGFYKFGLELCFCVTVVTACLRADAFSVLYLLLMLFFLFTPRQVCGKLWLPYMIFLAALIPVQYAGCVGFPPGICWSYPWLTDSVDINNLLQWLFVPGQYGSPTAKKLTADFFQFVAVALQYQVFKIEKRFSVKEYGGGSNKPVLINNVPAKDERDFVSAKESYLDYLRHLIFYWSYWVSLAIVLATGVTWITLFCLGYMILSFIYLWMGQNVMLRKRSSLIKSWNVIIGYNFCVILAKCSLQVVGCVY--WARMSHQCWFIQLFGVQCMDPMSWSRFEPPV---YDKQCETVSSGLHWDVICFIFILFQRKVFMTQSFSHVVFDLNVQSQFASRGAYLINRKLMTDISEQLAREELSLAKIREKLAVIQRRQAVLGRNTDNITEHYIMIRSGDYYLF 1510

HSP 2 Score: 625.55 bits (1612), Expect = 1.468e-177
Identity = 298/487 (61.19%), Postives = 375/487 (77.00%), Query Frame = 2 
Query: 5651 LLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETT---NDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIV-------DKEQDGR----------------NKIKSSYEESSPTSNKWSC---------NPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGY 7006
            LL I+LGN+AI+YSE+ CY LL++NHM S N+ SL YPL+VFLW MLSVPRP+K FWI LITYTE+VIVIKYIFQF FI+FN+ +    D  + LWIP ++G+EKS +YAI DL+QL+ +FLHRG+LKN+GLWRDHTEF QDL++V       ++ Q+G                 +++   +   + TS + +          NP  K+RRFY KMT+P+FNKKVDVY++MFLCEFI+F II+FGYVSFGP T   DNAF+FI++N++P PF+ M++ QF+FII+DR LFLRKQV GKFIFQI HVLLIH WLFF LP ITK  F +  APQLLY +KC+YF+LSAYQ++SGYPLRILGNFLT+ +NYINL LFKGY+I+PFLYELRN+MDWMWT+++++L+HWME+EDV+ KIFV KCWRRSE+ YPT RG  R    K  VGGL+LAFFF C W PL LSSFIG TFV NPP+ CTFS+S+GG+
Sbjct: 2448 LLLIALGNMAIVYSEWFCYLLLVVNHMRSSNILSLVYPLVVFLWGMLSVPRPTKTFWIFLITYTEVVIVIKYIFQFRFITFNDPSLKPADSAEALWIPRLLGVEKSGHYAIFDLVQLISLFLHRGFLKNDGLWRDHTEFVQDLQLVAERNKVAERVQNGERVGPDFLRLLSTESAASQMTERHNVDAVTSGRLTVSRRDTLHTWNPFAKLRRFYHKMTDPQFNKKVDVYIYMFLCEFISFWIIMFGYVSFGPSTGMGDNAFEFIRSNRVPFPFVCMLLVQFIFIIVDRGLFLRKQVLGKFIFQILHVLLIHGWLFFILPQITKSPFTAGFAPQLLYLIKCVYFSLSAYQIRSGYPLRILGNFLTKKYNYINLILFKGYLIIPFLYELRNIMDWMWTNSTLSLYHWMELEDVYAKIFVHKCWRRSEIAYPTPRGVNRPAGKKALVGGLILAFFFACLWIPLALSSFIGATFVFNPPVLCTFSLSIGGF 2934

HSP 3 Score: 222.631 bits (566), Expect = 8.604e-54
Identity = 135/378 (35.71%), Postives = 197/378 (52.12%), Query Frame = 2 
Query: 7010 PLFYFISRENNLKSLPKDTFDKMKECYKN--------------------------FSPP------------TDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTES-LKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQ-----------------SSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKE--NEARWWEIQE--IVAGETYCSNEKIPKQSHS---NLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKT 7954
            P+F F SRE N+  + +   D    C++                           F P               +L +FE  D+  I+IDG S ++W ITPPS + L  KL    S L ++    C R++ + +T++  V    +++L   +K  L   +                     SS  V ++A+ PR+L   +  L  A A L   N TY+N++  + ++      WWE++E  I + +      + P    S    L++  F+ERVSD+LFG  F  YGI+GMY AY+F+ +R+ R  Y++ISY+IR EELPHVDRILNL NEIYLVRENK+ RLEEQL+AKL FLYRS+ETMIKWTRH K I+ +  +++
Sbjct: 3023 PVFEFTSREGNILKIRQQDLDSFTRCHEKDLLEGKLNVKETTHKVAENSSTAHDRFRPSWGSSARRSPRQTVGFLNNFEVDDLRYITIDGFSGNIWAITPPSYDTLVKKLSDASSDLLLHSHMQCRRKTKEIQTSQISVEDIYSRKLQPLEKIELYGVLNTTAVGSASNNTQVKPSSRVLSSSPVTLNAVMPRYLVLKRDRLRPAYATLGLEN-TYINVSFVIHRDPAKNQSWWELKERAITSSDACFEKLRFPTLGDSWADALSIMTFNERVSDSLFGKWFFTYGILGMYGAYLFLVNRLFRTVYTNISYVIRLEELPHVDRILNLCNEIYLVRENKLLRLEEQLVAKLFFLYRSSETMIKWTRHPKRIIDQFTDRS 3399

HSP 4 Score: 186.808 bits (473), Expect = 5.830e-43
Identity = 133/380 (35.00%), Postives = 207/380 (54.47%), Query Frame = 2 
Query:  113 VTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFI-RYNRXXXXXXXXXXXXXXXTVSGLFSLSISLFHIPLIFNPLF---LSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQS-RKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFE 1234
             + D +LLR  L   L   T+ RYNGFSF YLL LL CP + + +  + +  IQ+FL +L+T+S +F+LS    HI L   P +   L  C +  ++I+ QIG+  L GVL YR +RLVLPD   L  ++ LL+Y  +          H    ++ +    ++  G                L     +E +   + S  +++ N++  +    K+  +   L      D  ++K+WRAWA+ +  V  +V++    GI SPS+ +++YL  FLGI T+WAC + +    FA +RIFLL+YS +HVCL YL Q  F Q   P N F++RLLGLYY++ T+C   GE+ F    R +D+++P + +++YY+ A ET RW E
Sbjct:    2 ASLDTVLLRVVLVTALFLVTVVRYNGFSFAYLLFLLACPLLPQPSSSNSKTKIQVFLTLLVTLSCVFTLSHPTLHIILAVAPPYDDALKTCEE--STIAAQIGVQRLNGVLPYRAMRLVLPDIFILAVAVGLLVYVSRRG--------HGGPRRQASVARNVAASGQD------------YSLAPRDISERTLAPYGSPPVVANNSSSANPLFGKLTSSMAALPFPRAWDENRRKLWRAWAVDNFCVLLSVLLVCVTGITSPSVPSAIYLLSFLGIGTYWACRSGMNPVPFACLRIFLLVYSGLHVCLYYLYQFPFFQSICPANGFTARLLGLYYIMQTTCDKPGEILFPVDVRIVDFIAPPLTIFLYYVLAFETWRWLE 359
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Cavefish
Match: piezo2a.2 (piezo-type mechanosensitive ion channel component 2-like [Source:NCBI gene;Acc:103047759])

HSP 1 Score: 462.225 bits (1188), Expect = 2.447e-130
Identity = 237/594 (39.90%), Postives = 364/594 (61.28%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERR-SSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDH---NQTYLNLTLSMKKENEA-----RWWEIQEIVAGET-YCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHN 7921
            +R+F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P  F+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T+++F+  +  QL YFVKCIYF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IFVLKCWR SE  YP  RG  ++   KY +GG+++       W PL   S + +   V N P++ + +I++GG+ P+F   +++N LK + +  F K    Y        +L ++ A DVT+  ++G+S+ +WTI+PPS + L   L   +   + M    +R  S  +K    M +H     LD N ++ L+  +   ++  V+ I  +FP F+    R  S++ A   DH   +  Y ++TL +K+ + +      WW + +  AG     S  K  ++  + L +++FS++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR  
Sbjct: 2240 IRQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPEAFLVMVLIQFGTMVVDRALYLRKTVMGKVIFQVILVFGIHFWMFFILPGVTERRFSQNMVAQLWYFVKCIYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFVLKCWRESEKRYPQPRGQKKKKVVKYGMGGMIVMLLICIVWFPLLFMSLVKSVAGVVNKPLDVSVTITLGGFQPIFTMSAQQNQLKDVTEAEFLKFMNSYNYIPGAMQFLEAYTAEDVTEAELEGNSNSLWTISPPSRKSLMEVLSKEDQFPVTMSWTIQRNLSLGAKAEVAMDKHVT--YLDTNTRQELINLLNGTRNKAVI-IKEVFPCFI----RAPSDSNAKPIDHLYGDNGYKDITLDLKRSDNSSGEIQEWWIVDQPSAGMIDMKSGVKTEQKREAGLRLYVFSDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPCVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTREK 2824

HSP 2 Score: 433.721 bits (1114), Expect = 1.345e-121
Identity = 336/1247 (26.94%), Postives = 595/1247 (47.71%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRG--EVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKE---------AVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGD---ITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINT---AIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFN-LTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKL-----------SSMNRFLYGDS------------------REVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAF----------------------------QIIIEKLK-------QFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSL---YTT----NFNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCP-NATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDX-XXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTI------DKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEE 4264
             VVVT   G  GI+ PS+ ++VY F FLG+CT+W+         F+ + + + ++SA H+ +LYL Q +F Q  +P  +  ++L G+  +V ++C      EVN     W  +++P +++ +YY  AT  R W ++  +++       +D     ++Q    + ++    +K+           ++   L+ +S     +  ++   N  +  +          +    SE  DS   SM  +D  + + P  + +P +   + +++ T    ++ S++   IAMMAWS+TY SW++F+ L+ +C LWM+ D RK  +  SP +VFY  +LI++QYI+ F  LT +P                 F K  +P   L   I  L+ FWL LR  +T+       + + L+D + +  S              +   + S +  +  KYWI +C     FVS +  +V+++I+YM++ ++ +  +   Y  WR  +  FW  ++VY+++VL+ IYT+QF    ++W N TGLS+E L+D+GL+ +  + LF  +  P  FL+V I+ + YFH  FL+L           S+++R ++ D                    E+G   D +++          +  +E+VN  +                             +++++L        Q+   +   +W   E H  KIV   I+   + E +  N V ++      PF +   +  +    W  + ++ KM+YQL ++    +S  CS+   YT     + N S      +D A W+GL+K +   +++     +L + A + V  Y  + FY+   N T P +  IF   T Q +DD ++N  K+ IN+ FYK GLE  F++ V V   R+D         L+ +    +RK  + +W  Y  FL  +L  +Y IC+G+PP  C  YP     +S+  N+ +WL+LP +   P++  ++ DF   +  +LQ RVF  E+   V    G      +C +L            DF+  + SY+D LK  +F + +W  L I+F TG   I++FC+GY++  F +L  G  ++L+   +++  W+ +I YN FVI  K  L +  C Y+  +++   CW+I LF + C     + R     N+    P  S ++G+ WD  CF  ++LQR++FM+  F HVV D+      ASRGA L    ++ +++  +++EE
Sbjct:  252 KVVVTILLGLTGIMLPSLTSTVYFFTFLGLCTWWSFCRSFDPLLFSCLCVLMAIFSAGHLIVLYLYQFQFFQEAVPREDNYAKLFGISPMVMSNCSHTWMFEVN-PKLEWHHFVNPIMLLVLYYTLATLVRLWLQESEDTMKEKDDDDDDEGEGEVEQELSENMKIHQTAEKKREIWRMAHYRTDEKNVLIVTSNGGPVDLMSLSHENGPVTPELYSTPHYKAGLAESGSERMDS---SMYEIDPVQDELPGALSSPEKAERVNAVVKTFRFIMKQSYICALIAMMAWSITYVSWLTFVFLIWSCTLWMVRDRRKYAMLTSPFMVFYGNLLIVLQYIWSFETLTPVPGL---------------FLKKEVPFRELGSKILCLLSFWLLLRQALTERRERQRDETQ-LSDIRVEDCSPEKEMEEEPGEQREMMDVLGSTVMAMLNKYWIYICGGMFFFVSFEGRIVMYKIIYMMMFLFCVALYQVHYERWRWMLKYFWMSIVVYTMLVLILIYTFQFESSIHVWSNMTGLSKEKLEDLGLEQFSVAALFTRIFIPTSFLLVCILHLHYFHDRFLQLTDIKSVADKQKSTISRLVHLDGSLADISMIKPEFNASVKEEEMG---DRVDLDEDEEDVKKKAEEVEEVNDVYCKTATFTCHIAPAPAPEPVCKDDLKNKWHLVVDRLTVLFLKFLQYIHQLQLLIWWLLELHVIKIVSSYIIWVSVKEVSLFNYVFLVSWAFALPFSQFRPLASSVCTVWTCVIIVCKMLYQLTSIQPETYSKICSMPHNYTELQRIDMNNSTLYSSPVDPANWVGLKKFSPLLENLRNNLLMLALLA-FEVTVYRHQDFYRMRNNLTAPVSRTIFHNITRQHLDDGIVNCAKYFINYFFYKFGLETCFLLAVNVIGQRMDFCAMFHAFGLIAVLYQRRRKAIALVWPKYCCFLACMLTFQYLICIGIPPAACSDYPWRNPSSSMDSNVVKWLYLPDFRTKPNSLFLLYDFMLLLCASLQRRVFEEEDDSAVRLLAGDNVE--ICRDLDAASFSQHNPVPDFIHCR-SYLDMLKVIMFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGELLLKPIKSILHYWDFLIAYNVFVITMKNILSIAACGYIKALVTNH-CWLIQLFSLAC-TIKGYSRPEQQANKQCELP--SDEAGIIWDSICFASLLLQRRVFMSYYFLHVVADIRSSQVLASRGAELFQATIVKAVK-ARIEEE 1466

HSP 3 Score: 117.857 bits (294), Expect = 1.734e-25
Identity = 74/149 (49.66%), Postives = 98/149 (65.77%), Query Frame = 2 
Query: 5600 EEYLKEQEXXXXXXXXXL-LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTN-DRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW 6040
            +E L+E E   S     L L  +L N+ + +SE VCY ++ILNHM+S ++ +L  P+++FLWAMLSVPRPSK FW+  I YTE+ IVIKY FQF F  FN+    D+  P   P IIG+EK + Y   DL+QLL +F HR  LK +GLW
Sbjct: 1958 DEELEESERFYSSQPQILQLCYALYNMLVAHSEMVCYLVIILNHMISASVATLVLPILIFLWAMLSVPRPSKRFWMTAIVYTEVTIVIKYFFQFGFFPFNQNIELDKSKPFHPPNIIGVEKKEGYVHYDLVQLLALFFHRSILKCHGLW 2106
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Cavefish
Match: piezo2a.2 (piezo-type mechanosensitive ion channel component 2-like [Source:NCBI gene;Acc:103047759])

HSP 1 Score: 455.677 bits (1171), Expect = 2.046e-128
Identity = 238/594 (40.07%), Postives = 366/594 (61.62%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSP--PTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERR-SSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDH---NQTYLNLTLSMKKENEA-----RWWEIQEIVAGET-YCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            +R+F+  + +P+++   DVYV MFL + + F+II+FG+ +FG  + +AD     +  +++P  F+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T+++F+  +  QL YFVKCIYF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IFVLKCWR SE  YP  RG  ++   KY +GG+++       W PL   S + +   V N P++ + +I++GG+ P+F   +++N LK + +  F  +  C   F P     +L ++ A DVT+  ++G+S+ +WTI+PPS + L   L   +   + M    +R  S  +K    M +H     LD N ++ L+  +   ++  V+ I  +FP F+    R  S++ A   DH   +  Y ++TL +K+ + +      WW + +  AG     S  K  ++  + L +++FS++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR
Sbjct: 2093 IRQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSS-LSEDQVPEAFLVMVLIQFGTMVVDRALYLRKTVMGKVIFQVILVFGIHFWMFFILPGVTERRFSQNMVAQLWYFVKCIYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFVLKCWRESEKRYPQPRGQKKKKVVKYGMGGMIVMLLICIVWFPLLFMSLVKSVAGVVNKPLDVSVTITLGGFQPIFTMSAQQNQLKDVTEAEFLNLM-CNICFFPQGAMQFLEAYTAEDVTEAELEGNSNSLWTISPPSRKSLMEVLSKEDQFPVTMSWTIQRNLSLGAKAEVAMDKHVT--YLDTNTRQELINLLNGTRNKAVI-IKEVFPCFI----RAPSDSNAKPIDHLYGDNGYKDITLDLKRSDNSSGEIQEWWIVDQPSAGMIDMKSGVKTEQKREAGLRLYVFSDKVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPCVDRILKLCTDIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTR 2676

HSP 2 Score: 440.654 bits (1132), Expect = 8.471e-124
Identity = 338/1207 (28.00%), Postives = 595/1207 (49.30%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRG--EVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSV----SKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINT---AIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFN-LTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKL-----------SSMNRFLY--GDSREVGPFEDNLNIXXXXXXXXN------------VSAFIEDVNSAFQIIIEKLK-------QFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSL---YTT----NFNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCP-NATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDX-XXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTI------DKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEE 4264
             VVVT   G  GI+ PS+ ++VY F FLG+CT+W+         F+ + + + ++SA H+ +LYL Q +F Q  +P  +  ++L G+  +V ++C      EVN     W  +++P +++ +YY  AT  R W ++  ++   +    +   +S+  Q       +Q +    AV  TG  + S V    S  G    +   ++  +     ++ +  +  +E  DS   SM  +D  + + P  + +P +   + +++ T    ++ S++   IAMMAWS+TY SW++F+ L+ +C LWM+ D RK  +  SP +VFY  +LI++QYI+ F  LT +P                 F K  +P   L   I  L+ FWL LR  +T+       + + L+D + +  S              +   + S +  +  KYWI +C     FVS +  +V+++I+YM++ ++ +  +   Y  WR  +  FW  ++VY+++VL+ IYT+QF    ++W N TGLS+E L+D+GL+ +  + LF  +  P  FL+V I+ + YFH  FL+L           S+++R ++  G   ++   +   NI   +   +             +S    D+ + + +++++L        Q+   +   +W   E H  KIV   I+   + E +  N V ++      PF +   +  +    W  + ++ KM+YQL ++    +S  CS+   YT     + N S      +D A W+GL+K +   +++     +L + A + V  Y  + FY+   N T P +  IF   T Q +DD ++N  K+ IN+ FYK GLE  F++ V V   R+D         L+ +    +RK  + +W  Y  FL  +L  +Y IC+G+PP  C  YP     +S+  N+ +WL+LP +   P++  ++ DF   +  +LQ RVF  E+   V    G      +C +L            DF+  + SY+D LK  +F + +W  L I+F TG   I++FC+GY++  F +L  G  ++L+   +++  W+ +I YN FVI  K  L +  C Y+  +++   CW+I LF + C     + R     N+    P  S ++G+ WD  CF  ++LQR++FM+  F HVV D+      ASRGA L    ++ +++  +++EE
Sbjct:  210 KVVVTILLGLTGIMLPSLTSTVYFFTFLGLCTWWSFCRSFDPLLFSCLCVLMAIFSAGHLIVLYLYQFQFFQEAVPREDNYAKLFGISPMVMSNCSHTWMFEVN-PKLEWHHFVNPIMLLVLYYTLATLVRLWLQESEDTSAVI----DLCSISACMQCVLQCSYVQFVQYVNAV--TGVKILSQVLIVTSNGGPVDLMSLSHE--NGPVTPELYSTPHYKAERMDS---SMYEIDPVQDELPGALSSPEKAERVNAVVKTFRFIMKQSYICALIAMMAWSITYVSWLTFVFLIWSCTLWMVRDRRKYAMLTSPFMVFYGNLLIVLQYIWSFETLTPVPGL---------------FLKKEVPFRELGSKILCLLSFWLLLRQALTERRERQRDETQ-LSDIRVEDCSPEKEMEEEPGEQREMMDVLGSTVMAMLNKYWIYICGGMFFFVSFEGRIVMYKIIYMMMFLFCVALYQVHYERWRWMLKYFWMSIVVYTMLVLILIYTFQFESSIHVWSNMTGLSKEKLEDLGLEQFSVAALFTRIFIPTSFLLVCILHLHYFHDRFLQLTDIKSVADKQKSTISRLVHLDGSLADISMIKPEFNILQHTVDLNTLFLSRSCMYPDPLSCLCADLKNKWHLVVDRLTVLFLKFLQYIHQLQLLIWWLLELHVIKIVSSYIIWVSVKEVSLFNYVFLVSWAFALPFSQFRPLASSVCTVWTCVIIVCKMLYQLTSIQPETYSKICSMPHNYTELQRIDMNNSTLYSSPVDPANWVGLKKFSPLLENLRNNLLMLALLA-FEVTVYRHQDFYRMRNNLTAPVSRTIFHNITRQHLDDGIVNCAKYFINYFFYKFGLETCFLLAVNVIGQRMDFCAMFHAFGLIAVLYQRRRKAIALVWPKYCCFLACMLTFQYLICIGIPPAACSDYPWRNPSSSMDSNVVKWLYLPDFRTKPNSLFLLYDFMLLLCASLQRRVFEEEDDSAVRLLAGDNVE--ICRDLDAASFSQHNPVPDFIHCR-SYLDMLKVIMFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGELLLKPIKSILHYWDFLIAYNVFVITMKNILSIAACGYIKALVTNH-CWLIQLFSLAC-TIKGYSRPEQQANKQCELP--SDEAGIIWDSICFASLLLQRRVFMSYYFLHVVADIRSSQVLASRGAELFQATIVKAVK-ARIEEE 1379

HSP 3 Score: 117.087 bits (292), Expect = 2.520e-25
Identity = 74/149 (49.66%), Postives = 98/149 (65.77%), Query Frame = 2 
Query: 5600 EEYLKEQEXXXXXXXXXL-LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTN-DRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW 6040
            +E L+E E   S     L L  +L N+ + +SE VCY ++ILNHM+S ++ +L  P+++FLWAMLSVPRPSK FW+  I YTE+ IVIKY FQF F  FN+    D+  P   P IIG+EK + Y   DL+QLL +F HR  LK +GLW
Sbjct: 1805 DEELEESERFYSSQPQILQLCYALYNMLVAHSEMVCYLVIILNHMISASVATLVLPILIFLWAMLSVPRPSKRFWMTAIVYTEVTIVIKYFFQFGFFPFNQNIELDKSKPFHPPNIIGVEKKEGYVHYDLVQLLALFFHRSILKCHGLW 1953
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Cavefish
Match: PIEZO2 (piezo type mechanosensitive ion channel component 2 [Source:HGNC Symbol;Acc:HGNC:26270])

HSP 1 Score: 447.973 bits (1151), Expect = 4.703e-126
Identity = 240/590 (40.68%), Postives = 356/590 (60.34%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTES-LKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLK-AIEANQSSY---VVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            +R+F+  + +P ++   DVYV MFL + + F+II+FG+ +FG     AD     +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP +T+++F+     QL YFVKCIYF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ ++PFL ELR VMDW+WTDT+++L  W+ VED++  IFVLKCWR SE  YP  RG  ++   KY +GG+++       W PL   S + +   V N P++ + S+++GG+ P+F   +++ NL S+    FD   + +   S    +L ++   D+T   ++GSS+ +WTI+PPS + L   L   +S   + M    +R  S    +E M        LD+  K  L K  IE N +      V I +IFPR+L    R  S++ A L +   T ++L L+  +++   WW + +   G     + KI       L ++IFS++VS    G L + YGI+G+Y + + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE L AKLIFLYRS ETMIKWTR  K
Sbjct: 2109 IRQFFYNLIHPDYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHQGGADITSS-LSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVMGKVIFQVVLVFGIHFWMFFILPGVTERRFSQNRIAQLWYFVKCIYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLIPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHIFVLKCWRESEKRYPQPRGQKKKKVVKYGMGGMIVMLLICIVWFPLLFMSLVKSVAGVVNTPLDVSVSLTLGGFQPIFTMSAQQKNLNSITSAKFDNFVKHFSKNSFAVQFLEAYVYQDLTVAHLEGSSNSMWTISPPSKKNLIGMLNQADSDFPLTMTWSIQRNLSLGAKSE-MATGKKIINLDKETKIQLAKLLIETNSTDAHKKPVCIKSIFPRYL----RAPSDSNAKLIEQLSTDIDLFLNRAEDSNKEWWVVNQTKFGLLKLESVKI--NDSPRLELYIFSDQVSPPSLGFL-AGYGIMGLYMSVVLVIGKFVREFFSGISHTIMFEELPNVDRILKLCTDIFLVRETGELDLEEDLYAKLIFLYRSPETMIKWTREKK 2689

HSP 2 Score: 271.552 bits (693), Expect = 3.507e-72
Identity = 181/613 (29.53%), Postives = 309/613 (50.41%), Query Frame = 2 
Query: 2621 DVNSAFQIIIEKLK-------QFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNC----SLYTTNFNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQR-KICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL----TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTI------DKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCI----NPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGD 4372
            D+ S + +++++L        ++F  +   +W   E H  KIV F I+  C+ E +  N VL+       P+ +  T+  +    W  + +  KM YQL+T+   N+S  C    ++     N+S+   D +D A W+GL K      ++     ++ + A    +  HQ  F +    + P +  IF + T Q +D+ +IN  K+ IN++FYK G+E+ F++ V V   R+D YS+++   L   +  +R K  ++IW  Y  FL  ++  +YA+C+G+PP  C  YP     ++   N+ +WLFLP +   P++  ++ DF   +  +LQ +VF  EN   V    G      +C +L            DF+  + SY+D LK  +F + +W  L I+F TG   I++FC+GY++  F +L  G  ++L+    L+  W+ +I YN FVI  K    L+ C Y+D M  K  CW+I L  + C      P + DR  L  +          ++G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ ++R +  +E   ++++K ++D+I  RQ +  K +     +   SGD
Sbjct:  798 DLKSKWHLVVDRLTVLFLKFLEYFHKLQLFIWWLLEMHIVKIVPFYIILVCVKEVSLLNYVLLASWAFALPYRQFRTLASSICIVWTCVIITCKMFYQLETIEPRNYSVECLKPENITDVYINQSLLYTDPVDPANWVGLRKSKELLTYLTNDLLIVAILAFEVTIYRHQEYFRRHNKLSPPPSRTIFHDITRQHLDNGIINCIKYFINYSFYKFGVEVCFLLAVNVIGQRMDFYSMLHAFALAAVMYRRRRKAIAEIWPKYCCFLACMITFQYAMCIGIPPAACSDYPWRFPSSTTNSNVIKWLFLPDFSTRPNSMFLLYDFMLLLSASLQRQVFDEENKAAVRLMAGDNVE--ICRDLDAASFSVHNPVPDFIHCR-SYLDMLKVIMFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGELLLKPIKKLLHYWDFLIAYNVFVITMKNIFSLLACGYIDSM-QKNSCWLIQLLSLACTIKEYTPPNTDRCDLPKD----------EAGIIWDSICFSFLLLQRRVFMSYYFLHVVADIRAGQILASRGAELFQASIVKAVRARLEEENKSMEQLKRQMDRIKTRQQKFKKGKEKMLSMTQESGD 1396

HSP 3 Score: 141.354 bits (355), Expect = 1.099e-32
Identity = 94/337 (27.89%), Postives = 175/337 (51.93%), Query Frame = 2 
Query: 1604 IRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFN-LTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMT---DTLLNASKQNEIL--NDSKFDQSSNADSEAYFGN--------------------VDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQE--PVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLY 2530
            ++ S+V   IAMM WS+TY SW++F+ LL +C LWM+ D RK  +  SP +V Y  +L+++QYI+ F  L ++P+                F    +P   L+  +  L+ FWL LR  +T   D L   +  +E+    + K +  +  +++ + G+                    ++N + + +   +  +  KYWI +C      VS ++   + ++++ YM++ ++ +  +   +  WR+ +  FW  V+VY+++V++ IYT QF      W   TG+S E L  +GLK +E ++LF+ +  P  FL+V I+ + YFH+ FL+L+ +   ++
Sbjct:  397 MKQSYVCALIAMMTWSITYVSWLTFVFLLWSCALWMVRDRRKYAMLTSPFMVAYGNLLLVLQYIWSFETLKDVPDI---------------FKTPTVPFSELSSKVLCLLSFWLLLRQTLTERQDKLKEEAVLSEVTVETEKKGETQTRPENKWFTGHKHFKIFVCFADEEKQVEEDGMENDLVQVVGKLVMAMLVKYWIYICGSMFFLVSFEDVDHIAMYKVFYMMMFLFCVAMYQVDFERWRRILKYFWMSVVVYTMLVVILIYTCQFTTSVPFWSKVTGVSTESLGKLGLKQFEVTELFRRIFIPTSFLLVCILHLHYFHEHFLELTDIKTIIH 718

HSP 4 Score: 116.316 bits (290), Expect = 4.246e-25
Identity = 73/154 (47.40%), Postives = 99/154 (64.29%), Query Frame = 2 
Query: 5654 LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFA--QDLEIVDKEQDGRNKI 6109
            L  +L N+ + +SE V Y ++ILNHM+S ++ +L  P+++FLWAMLSVPRPSK FW+  I YTE+ IVIKY FQF+F  FN+   DR  P   P IIG+EK   Y   DLIQLL +F HR  LK +GLW +    A  +D  +  +E +   K+
Sbjct: 1837 LCYALYNLLVAHSEMVSYLVIILNHMISASMVTLVLPILIFLWAMLSVPRPSKRFWMTAIVYTEVTIVIKYFFQFSFFPFNQNMIDRNKPYHPPNIIGVEKKDGYVHYDLIQLLTLFFHRSILKCHGLWDEDDPKAKKKDTPLHREESEDEEKM 1990

HSP 5 Score: 78.5666 bits (192), Expect = 1.183e-13
Identity = 43/134 (32.09%), Postives = 76/134 (56.72%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH-RWIDYLSPCIIMYVYYLCATETRRWFE 1234
             VVVT   G  G++ PS+ ++VY F FL +CT+W+  +   T  F+ + + + ++SA H+ LLYL Q +F Q  +  N+  +RL G+  +V T C +   +  +   +W   ++P +++ +YY  AT  R W +
Sbjct:  209 KVVVTILLGVTGMMLPSLTSAVYFFVFLALCTWWSFCHTFDTLLFSCLCVLMAIFSAGHLFLLYLFQFQFFQDSISVNDTYARLFGISGIVKTDCVSTWRLTVHADVKWHHCVNPIMLLILYYTLATLIRLWLQ 342
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Cavefish
Match: piezo1 (piezo-type mechanosensitive ion channel component 1 [Source:ZFIN;Acc:ZDB-GENE-041111-255])

HSP 1 Score: 443.736 bits (1140), Expect = 7.167e-125
Identity = 337/1173 (28.73%), Postives = 558/1173 (47.57%), Query Frame = 2 
Query:  869 GIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLY-YLVNTSCQTRGEVNFYT-HRWIDYLSPCIIMYVYYLCAT----ETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLT-ELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRF-------LYGDSREVGPFEDNLNIXXXXXXXXN---VSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTN---------FNKSM--DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKIC-SKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPL---------TSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRN-RPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCS--SVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEE 4264
            GI  PS  +SVY   F+G+CT+WAC   +    F  + + +  ++A H+  LYL Q +  Q     ++  +RL GL   ++  +C +   +   T H W  Y++P I++ +Y   AT     T  + E G      ++ +       + ++S + D +  L+   E+  Q  +                 P  T +    G         S   D    + AV  ++   S LL+           +    ++ S++   IAMM WS+TY SW++F+LLL AC +WM+   R   +  SP I+ Y   L  +QY++  +L  ELP+         + L ++G  +   P   L  M+ F + FWL LR  + D      KQ   L +    +++  D         + I K +   +  +  KYWI VC    + VS    +V ++IVYMLL +  +  +   YS WR+ +  FWW V+ Y+++VL+ IYTYQF  FP  W+N TG +EE L DIGL+T++ S+LF  ++ P  FL+  I+Q+ YFHKPF+K++ +          +   S   G  E++L        + +   V +    V     ++  K      +I A +WR  E H  KIV F +V   + E +  N+VL++L     P+ +   +    S  W  + ++ KM+YQL  VN   +S NC++  +N          N ++  D +D A W G  K      +      VL++      V  HQ   Y+    + P    IFP+ T   +D  L+   K+ +N++FYK GLE+ F++TV V   R++   + +   L+  +  +R++  +KIW  Y LFL + +  +Y +CVG+PP LC  YP          + L E+ +  L+             +ADF   +  + Q++VF  E        GG  N  P   + LP     +F++ + SY+D +K  +F + +W  LA+VF TG   I++F LGY++ +F +L  G  +++++    +  W+ +I YN  VI+SK  L ++ C ++  M   RFCW+I LF + C     +D   L     +   CS    ++G+ WD  CF F++LQR++F++  F HV  DL    R ASRG  L    ++ ++R  K  E+
Sbjct:  176 GITLPSAFSSVYFLLFIGVCTWWACHFPISHLGFNALCVMVSFFTAGHLVCLYLYQSDLAQTIFTPDSLWARLFGLKDIIIPANCSSSDALILNTEHDWPVYVNPGILLLLYITVATILKISTHSYSEVGSGEEVELKQW------GAGRKSPDDDTKQMLLASGESPGQESN-----------------PTNTKEHVTNG---------SGQHDLGLSTSAVQQEEEEDSALLL-----------VGRMIMQQSYICALIAMMVWSITYHSWLTFVLLLWACLIWMLRARRHFAMLCSPFILLYGLGLCCLQYVWAMHLEPELPQHV-----GYMSLRQMGLDRATYPCLRLGAMLLFTLTFWLLLRQSVKDIFWRKKKQTAPLQEVTTGENTGRD---------DSILKLLGRVVMSLYAKYWIYVCGGMFIMVSFAGKLVGYKIVYMLLFLLCMCLYQVYYSLWRRLLKPFWWLVVAYTMLVLIAIYTYQFEDFPDYWRNFTGFTEEQLSDIGLETFKLSELFTSIMIPGFFLLACILQLHYFHKPFMKITDLEHVTPLHRPEVLQSSEGRGFEEEDLQTDLGDDESEDGVMVPSKWGLVMDRLMVLFRKFSDILTLIQAFLWRILELHILKIVAFFVVWVALLEPSVMNLVLVVLWSFAMPYARFRPMASCLSTVWVCVIIVCKMLYQLSIVNPNEYSNNCTVPLSNETSLEMNEIVNSTLYKDPVDPANWFGFRKAATALGYSKNHLLVLLLLVFEATVYRHQVHHYRQLQRSPPTIPAIFPQATRDKLDQGLLPCIKYLLNYSFYKFGLEICFLMTVNVIGQRMNFLVIFHGCWLVAIMVRRRRVAIAKIWSKYCLFLVIFMIYQYILCVGIPPALCIDYPWRWKTSVTINSMLCEHFKCKLYCLCVCVCVCVCVCVADFLLLMCASQQWKVFENEKKEEWMVLGGENNDNPDPMDRLPFNPAPNFINCR-SYLDMMKVLVFRYMFWFVLAVVFVTGSTRISVFGLGYLLASFFFLLFGTRLLIKRSCTRLLMWDCLIIYNVTVIISKNILSILACVFVADM-QARFCWVIQLFSLVCTVKDYYDPASL-----NDKECSLPVEEAGIIWDSICFFFLLLQRRVFLSFYFLHVTADLQASARQASRGFELFRASIIKNMRFHKQAEK 1284

HSP 2 Score: 400.979 bits (1029), Expect = 1.090e-111
Identity = 223/590 (37.80%), Postives = 350/590 (59.32%), Query Frame = 2 
Query: 6176 RRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFIC-FWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPS-LEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSE-ATALLKDHNQTYLNLTLSMKKENE------ARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
             RF+  + + ++    DVY  MFL + + F+II+FG+ +FG  + +AD A   +  +++P  F+ M++ QF  ++IDRAL+LRK V GK IFQI  V  IH W+FF LP +T++ FN     QL YFVKCIYF LSAYQ++ GYP RILGNFLT+ +N++NLFLF+G+ +VPFL ELR VMDW+WTDT+++L +WM VED++  IF++KC R +E +YP  +G  ++   KY +GGL++ FF IC  W PL   S + +   V N P++ T ++ +GGY PLF    ++ +++   +  ++ + E + + +    ++  +   D+   +I+GSS  VW I+PPS  E +K  L S   + + +    +R  +   T E      +      N  +  L ++     +  V++  +FP ++ A     ++  + L +   + Y N+TLS+ ++          WW+I      ++  +   +P        + IF+++VS    G L + YGI+G+Y + + V  + +R F+S+IS+ I  EELP VDRIL L  +I+LVRE     LEE+L +KLIFLYRS ETMIKWTR
Sbjct: 1899 HRFFHNILHAEYRAATDVYALMFLTDVVDFIIIVFGFWAFGKHSAAADIA-STLSEDQVPEAFLVMLLIQFSTMVIDRALYLRKAVLGKLIFQIILVFGIHLWMFFILPAVTERMFNQNFVAQLWYFVKCIYFTLSAYQVRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIV-FFLICIIWFPLLFISLVRSVVGVVNHPVDVTVTVKLGGYEPLFTMSVQQQSIQPFTEADYNHLTELFGSNAVAMQFITLYSYEDIVTANIEGSSGSVWRISPPSRQEVIKELLGSPADMTLRLAWNFQRDLNKGGTVENTFDKHSINLEPGNPVRADLASLLVGNRTEPVRVPHMFPNYIRAPNGAEAKPVSQLYEGDEEGYQNVTLSLMRDGSLNGSGAQEWWDISVADCDQSSGACGVLP--------MIIFNDKVSPPSLGFL-AGYGIMGLYVSVVLVIGKFVRGFFSEISHSIMFEELPCVDRILKLCTDIFLVRETGELELEEELYSKLIFLYRSPETMIKWTR 2477

HSP 3 Score: 122.094 bits (305), Expect = 7.195e-27
Identity = 63/135 (46.67%), Postives = 94/135 (69.63%), Query Frame = 2 
Query: 5654 LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVD---PLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDH 6049
            L  +L NV   +SE  CYF+++LN+ ++ ++ SL  P+++FLWAML+VPRPSK+FW+  I YTE+++V+KY+FQF F  +N     R++   P + P I+G+EK+ NY   DL+QLL +F HR  L+  GLW DH
Sbjct: 1609 LLFALYNVLACHSELACYFIIVLNNAVTASVISLVLPILIFLWAMLAVPRPSKSFWMTAIVYTEVMVVVKYLFQFGFFPWNSEYETRLNENKPFFPPRILGLEKTDNYIRYDLLQLLALFFHRSLLQRYGLW-DH 1742
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Cavefish
Match: piezo1 (piezo-type mechanosensitive ion channel component 1 [Source:ZFIN;Acc:ZDB-GENE-041111-255])

HSP 1 Score: 81.2629 bits (199), Expect = 3.475e-15
Identity = 57/235 (24.26%), Postives = 115/235 (48.94%), Query Frame = 2 
Query: 6869 YSVGGLLLAFFFICF-WGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEK-LKVKLRSTESLKINMQAICERRSSDSKTTEKMV-RHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENE------ARWWEI 7543
            Y +GGL++ FF IC  W PL   S + +   V N P++ T ++ +GGY PLF    ++ +++   +  ++ + E + + +    ++  +   D+   +I+GSS  VW I+PPS ++ +K  L S   + + +    +R  +   T E    +H+   +     + +L   +  N++  V     +FP ++ A     +EA  + + + + Y N+TLS+ ++          WW+I
Sbjct:   44 YGMGGLIV-FFLICIIWFPLLFISLVRSVVGVVNHPVDVTVTVKLGGYEPLFTMSVQQQSIQPFTEADYNHLTELFGSNAVAMQFITLYSYEDIVTANIEGSSGSVWRISPPSRQEVIKELLGSPADMTLRLAWNFQRDLNKGGTVENTFDKHSINLEPGNPVRADLASLLVGNRTDRVPH---MFPNYIRAPNG--AEAKPVSQLYEEGYQNVTLSLMRDGSLNGSGAQEWWDI 272
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009619.1 (pep scaffold:Pmarinus_7.0:GL484020:1370:4517:1 gene:ENSPMAG00000008693.1 transcript:ENSPMAT00000009619.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.176 bits (313), Expect = 1.860e-32
Identity = 70/193 (36.27%), Postives = 109/193 (56.48%), Query Frame = 2 
Query: 7364 AIEANQSSYVVQIDAIFPRFLTAYKRTLSEAT-ALLKDHNQTYLNLTLSMKK-----ENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNK 7924
            A++   S     I  +FP +L A     S     +L +  ++Y ++ L +++      + A WW ++++            P +   ++ + +FS+RVS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDR+L L  +I+LVRE    +LEE L AKLIFLYRS ETMIKWTR  +
Sbjct:   13 ALDTFASRVCRLIKNLFPPYLKAPGGPDSTPVRQMLPEGERSYSDVELVLRQGSPASSSHAEWWSLRQL--------RSDCPGRRCDDIRIIVFSDRVSPPSLGFL-AGYGILGLYASVVLVVGKFVREFFSGISHSIMFEELPNVDRVLKLCTDIFLVRETGELQLEEDLYAKLIFLYRSPETMIKWTREKE 196
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Nematostella
Match: EDO30292 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T173])

HSP 1 Score: 242.662 bits (618), Expect = 1.996e-68
Identity = 121/311 (38.91%), Postives = 184/311 (59.16%), Query Frame = 2 
Query: 6335 IKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNF------SPPTDYLMSF----------------EAGDVTQISIDGSSDDVWTITPPS 7201
            ++ N +P  F+ M+++QF  IIIDR L+LRK V  K  F +F  +  H ++F  +P++TK+ F   I    +Y   C+YF LSAYQ++SGYP RILGNFLT+ +   +  LF+G+  +PFL ELR+V+DW+ TDT++ L+HW+++ED++  I+VLKC+R SE  +   RG    + SK++VGGLL+A   I  W PL   S+I + +  NPP + TF++S+GGY PLF   ++E  L+ L     D++K  +          PP    + F                + G V  + I G+S  +W I+PPS
Sbjct:  161 VEENVVPKTFLYMLLSQFFLIIIDRCLYLRKYVFAKLFFLLFLTVSFHVFMFIVVPYVTKRPFFKNIPAIFMYIFMCMYFGLSAYQVRSGYPTRILGNFLTKSYTLTSGVLFQGFQAIPFLLELRSVLDWVCTDTTLTLYHWLKMEDIYANIYVLKCYRESEKTWFQGRGQKYWMLSKWTVGGLLVALLVIVIWFPLLFMSYINSVYTSNPPQDATFTLSIGGYQPLFRVSAQEQFLERLNNTKIDRIKTQHPGLHQGADTQPPLQVAIIFNCVLKIQIDTFLADYHDRGTVVLVKITGNSSSIWQISPPS 471

HSP 2 Score: 93.2041 bits (230), Expect = 5.098e-19
Identity = 40/83 (48.19%), Postives = 65/83 (78.31%), Query Frame = 2 
Query: 7679 IIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKS 7927
            IIG+Y  ++++  + +R F++ ISY I  +E+P+VD++L L  +I++VRE+K F+LEE L AKL+FLYRS ET+IKWT++ ++
Sbjct:  496 IIGLYVGFVWLVGKFVRLFFTSISYRIMFDEMPNVDKVLKLCLDIFMVRESKSFKLEEDLFAKLMFLYRSPETLIKWTKYKRA 578

HSP 3 Score: 63.1586 bits (152), Expect = 1.337e-9
Identity = 26/58 (44.83%), Postives = 37/58 (63.79%), Query Frame = 2 
Query: 6839 RGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSP 7012
            RG    + SK++VGGLL+A   I  W PL   S+I + +  NPP + TF++S+GGY P
Sbjct:   94 RGQKYWMLSKWTVGGLLVALLVIVIWFPLLFMSYINSVYTSNPPQDATFTLSIGGYQP 151
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Nematostella
Match: EDO47371 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMM5])

HSP 1 Score: 179.874 bits (455), Expect = 4.054e-49
Identity = 117/367 (31.88%), Postives = 189/367 (51.50%), Query Frame = 2 
Query: 3110 NATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTS-LKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIEN-SLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMIS-KRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASR 4201
            N  +PE GI+F   + Q  DD ++   K+  N  FY  G E+S +V V+   +R DV S++Y + L  FL   R+  + IW  Y+ FL  LLP++Y + +G PPGLC  YP T  L  NL  WL+L    +P   K ++ DFFQ +F   Q  V+ +E  S T       ++R        K    DF+    +++D+ K  +F   YW++LA+V+ T    +++F  G+++  F +LW GQ + L+ R  L+  W + I YN+  +L+K  LQ++ C + D++      C  + L  + C+   ++        +   D  +   +GL  D  CF F++ Q +IF ++ F HVV D   Q+  A R
Sbjct:    7 NLMEPEPGILFESASRQKADDDMLQCVKYLFNRFFYHFGWEVSLVVMVVNMAVRCDVTSVIYALWLGSFLALGRQSSAVIWPVYVGFLAFLLPVQYLLVLGWPPGLCLAYPWTKVLDPNLSHWLYLTDVSFPSDPKLLLGDFFQLLFACCQENVYGLERYSWTAEE--TEQSRQTRRGSRVKFSTPDFM-WNITWLDFCKVTLFQHMYWVTLAVVYITVQSTVSIFNFGFILWCFFFLWHGQALYLQPRKKLLRLWKLFICYNYLTLLAKVCLQVVACVWQDYVTQYTSNCLPLQLLSMFCLRNSTYSGK----PQTGMDCVAPDDTGLAMDCACFTFLLTQYRIFTSEYFRHVVRDHREQSEMAYR 366
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Nematostella
Match: EDO47370 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMM3])

HSP 1 Score: 160.229 bits (404), Expect = 4.502e-40
Identity = 125/405 (30.86%), Postives = 203/405 (50.12%), Query Frame = 2 
Query: 5327 DPESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNE---KRLVKLKVLSKISNEVDGRIELEAIVVEIVGD-------GSHSFVNSKNQEEY----LKEQEXXXXXXXXXLLAISLGNVAIIYS-----EFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTN----DRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKE-------------QDGRNKIKSS-----YEESSPTSNKWSCNPIYK-MRRFYSKMTNPKFNK-KVDVYVFMFLCEFIAFLIIIFGYVSF-GPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDR 6409
            +PE   ++ K     +YY+     D +I +++  +K+YR I   L +E   KRL KL+      + +  R    +     V D       GS +  + ++ + +    +   +   S  +   + ++  +VA +Y+     + +CY L+ILNHM+   L S+P P +VF+W MLS+PRP+K +WI +ITYT+IVIVIKY+F+F F   N   +    D+ DPL    IIGIE+  + +  DL+ LL ++ HR  LK +GLWRD        E+ +                  RN   SS     Y+     S +   N I + ++ F +++ +P+     VDVY  MF C+FI F+II+F + +F  P           ++ N +P  F+ M+++QF  IIIDR
Sbjct:  104 EPEGLVTRLKKLFSWIYYYFAIAIDKVIDVLSDISKDYREIADQLKHERKEKRLEKLRRGRYSYSSLRARTLAASASAAEVSDSDVIENKGSATSRSDEDADSWSVLNIDLDDTDASNWKHSHMRVARFSVAFVYALLAHTDIICYLLMILNHMVYACLLSMPLPFLVFMWGMLSIPRPTKRYWITVITYTQIVIVIKYLFKFQFKFINNCNSSDGPDKNDPLCPARIIGIERDSHTSAYDLLLLLALYFHRYSLKVHGLWRDKAAHDDHDELYEPPLSPNSPKSEPTPFAGSRNMAASSPDSEQYQSDVEDSGESLWNKICRSVKAFLNRIYDPEVGSGAVDVYAIMFACQFIIFIIILFSWSAFSSPEPQRQAQFVKIVEENVVPKTFLYMLLSQFFLIIIDR 508

HSP 2 Score: 134.806 bits (338), Expect = 7.042e-32
Identity = 64/168 (38.10%), Postives = 101/168 (60.12%), Query Frame = 2 
Query: 6659 LFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMK------------ECYKNFSPPTDYLMS 7126
            L +   +  +PFL ELR+V+DW+ TDT++ L+HW+++ED++  I+VLKC+R SE  +   RG    + SK++VGGLL+A   I  W PL   S+I + +  NPP + TF++S+GGY PLF   ++E  L+ L     D++K            +  K+ S P DY+ +
Sbjct:  503 LIIIDRFQAIPFLLELRSVLDWVCTDTTLTLYHWLKMEDIYANIYVLKCYRESEKTWFQGRGQKYWMLSKWTVGGLLVALLVIVIWFPLLFMSYINSVYTSNPPQDATFTLSIGGYQPLFRVSAQEQFLERLNNTKIDRIKTQHPGLHQGADTQGTKDSSCPRDYIRA 670
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Nematostella
Match: EDO47372 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMM6])

HSP 1 Score: 113.235 bits (282), Expect = 1.550e-28
Identity = 54/138 (39.13%), Postives = 90/138 (65.22%), Query Frame = 2 
Query: 2093 FLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKL 2506
            ++  +  KYWIL+CC A L V +Q  V V++I YM + ++ L+ +  S + WR  +   WW +++YS+ +LL IYTYQF+  P  W N TGLS++ L ++GL+ +  + L   LLTP  F ++I++Q+ +FH+PF+ +
Sbjct:    2 WVKSVLAKYWILLCCGAFLLVGLQNEVSVYQIGYMAIFLFILICYQISITTWRLILRPLWWVMVIYSICILLIIYTYQFDNMPLYWHNATGLSDQWLYNLGLRQHTKASLLMELLTPTAFSIIIVIQLHFFHQPFMAM 139
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Nematostella
Match: EDO47369 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMM2])

HSP 1 Score: 93.2041 bits (230), Expect = 1.416e-22
Identity = 40/83 (48.19%), Postives = 65/83 (78.31%), Query Frame = 2 
Query: 7679 IIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKS 7927
            IIG+Y  ++++  + +R F++ ISY I  +E+P+VD++L L  +I++VRE+K F+LEE L AKL+FLYRS ET+IKWT++ ++
Sbjct:    1 IIGLYVGFVWLVGKFVRLFFTSISYRIMFDEMPNVDKVLKLCLDIFMVRESKSFKLEEDLFAKLMFLYRSPETLIKWTKYKRA 83
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Medaka
Match: piezo1 (piezo type mechanosensitive ion channel component 1 [Source:NCBI gene;Acc:101175341])

HSP 1 Score: 482.641 bits (1241), Expect = 2.426e-137
Identity = 364/1248 (29.17%), Postives = 593/1248 (47.52%), Query Frame = 2 
Query:  785 DRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLY-YLVNTSCQTRGEVNFYT-HRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNL-TELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGIC-EKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFL------------YGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEK---LKQFFEVIYAKV----WRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSM-------DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXX-XXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQ---------RWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENS---LTVNNYGGGRNRPI---LCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSV--KSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGDKYLF 4384
            + L+   W+   +Q L     V + G AGI  PS  ++ Y   FLG+CT+WAC   +    F+ + + +  ++A H+  LYL Q    Q   P ++  +RL GL  ++V  +C    E+   T H W  Y++P I++ +Y                +V R  S+      + ++ S+  DP     P K+       +L       G  +T+ RP+  +    A   T +   +S                   +  L   P+       +    ++ S+V   IAMM WS+TY SW++F+LLL AC +W++   R A    SP I+ Y  VL  +QYI+   L  ELP      S  T+ L ++G  K   P   L  M+ F++ FWL LR               ++ + +   SS    +       N    K+V  +   C  KYWI VC    + VS    +V ++IVYMLL +  L  +   YS WR  + +FWW V+ Y+++VL+ IYTYQF  FP  WKN TG ++E L  IGL+T++ S+LF  +L P  FL+  I+Q+ YFHKPF++++ +                  D+ E+   ED  N   S+          E + S + +++++   L + F  I +KV    WR  E H  K+V F  V   + E +  N+VL++L  +  PF +   +    S  W  + ++ KM+YQL  VN   +S NCS   TN  K +       + +D AKW G+ K      +      VL++      V  HQ   Y+    + P    +FP  T  S+D  L+   K+ +N+ FYK GLE+ F++TV V   R++   L++   ++ I +  +R   ++IW  Y LFL + +  +Y +CVG+PP LC  YP       LQ         +WL+LP +   P++  +MADF   +  + Q++VF  E +   + +         P+   L N  P     +F++ + SY+D LK  +F + +W  L++VF TG   I++F LGY++  F +L  G  +M+++    +  W+ +I YN  VI+SK  L ++ C ++ + + +RFCW+I LF + C     +DR+         D C+    ++G+ WD  CF+ ++LQR++F++  F HV  +L    + ASRG  L    MM ++   K  E+  L             Q +  +  ++    V+ SG+ YLF
Sbjct:  152 EHLKATAWKV--LQDLGRILAVGLLGLAGITLPSGFSAFYFLFFLGVCTWWACHLPISQLGFSALCVMVGFFAAGHIVCLYLYQSLLAQALFPPHSLWARLFGLKDFIVPGNCSLPDELILNTNHDWPVYVNPGILLLLYVTVV------------AVLRSGSH------TRVQGSHPRDPS----PLKQQGGPEAPVLEPCPQSRG-CRTLERPSPPMTRFLAEHETPLSLLYS-----------------YSNAFLFLRPSGESPFFLLGKVVMQQSYVSALIAMMVWSITYHSWLTFVLLLWACLIWILRARRHAATLCSPFILLYGLVLCCLQYIWAMELHPELP-----TSVGTMSLRQLGLDKAQYPCLRLGAMLLFVLTFWLLLR-------------QAVMENFRRKSSSQTPLQEVATKGQNQSMLKVVGGMVMSCYAKYWIYVCGGMFIMVSFAGKLVAYKIVYMLLFLLCLCFYQVYYSLWRHLLKLFWWLVVAYTMLVLITIYTYQFEDFPVYWKNLTGFTDEQLAAIGLETFDLSELFTSILIPGFFLLACILQLHYFHKPFMRITDLENVTPTHKRRNSDAVGSADAVELNTEEDPSNTEESADEGRTQKTTKELMPSKWGLVMDRLLVLSRKFSEILSKVQVFLWRLLELHILKMVAFFTVWVALQEASVMNLVLVVLWSLATPFCRFRPMASCLSTVWVCVIIICKMLYQLSVVNPEEYSRNCSTPLTNHTKLLLNSSLYKEPVDPAKWFGIRKDATALGYSKNHLIVLMLLVFEATVYRHQAHHYRQLQRSPPPIPAVFPSATRDSLDQGLVACLKYLVNYTFYKFGLEICFLMTVNVIGQRMNFLVLIHGCWMVAILVRRRRAAIARIWPKYCLFLSIFMIYQYLLCVGIPPVLCMDYPWRWSNPVLQDWGTLDALIKWLYLPDFFTVPNSGNLMADFVLLMCASQQWKVFDCERTEEWMVLAGENSDEPEPMEGRLFNPAP-----NFINCR-SYLDMLKVLVFRYFFWFVLSVVFITGASRISVFGLGYLLGCFFFLLFGTKLMVKRSRTRLILWDCLIIYNVAVIISKSVLSILACVFV-FKMQERFCWVIQLFSLVCTVKGYYDRD---------DTCTLPIEEAGILWDGFCFICLLLQRRVFLSFYFLHVSAELQASAKQASRGFELFRASMMKNMDFHKQAEDKSLS------------QLKRSQTLMSCCAAVIHSGEYYLF 1311

HSP 2 Score: 482.256 bits (1240), Expect = 4.094e-137
Identity = 302/795 (37.99%), Postives = 459/795 (57.74%), Query Frame = 2 
Query: 5687 YSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFN---ETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLK----NNGLWRDHTE---------------FAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKM------------RRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFIC-FWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSL-EKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATA-----LLKDHNQTYLNLTLSMKKENEA------RWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKS 7927
            +SE +CY +++LN+++S ++ S+  P++VFLWAML++PRPSK FW+  I YTE+++V+KYIFQF F S+N   E T ++  P + P I+G+EK+ NY   DL+QLL +F HR  L     N   +R   E                 +++ +  KE++   ++++  E+    ++    +   K+            + F+  + + K     DVY  MFL + + F+IIIFG+ +FG  + +AD A   +  +++P  F+ M++  F  +IIDRAL+LRK V GK IFQ   VL IH W+FF LP +T++KFN     QL YFVKCIYF LSAYQ++ GYP RILGNFLT++F ++NLFLF+G+ +VPFL ELR VMDW+WTDT+++L +WM VED++  IF++KC R +E +YP  +G  ++   KY +GGL++ FF IC  W PL   S + +   V N PI+ T ++ +GGY PLF    ++ +++      ++++ + +K+ +    ++  +   D+    I+GSS  VW I+PPS  E +K  L S   L + +    +R      T E    HT  K   + +  NL++A  A+          + P F   Y R  + A A     L K     YL +TLS+K +  +       WW+I          + E     S   L + IF+++VS    G L + YGI+G+Y + + V  + +R F+S+IS+ I  EELP VDRIL L  +I+LVRE     LEE+L +KLIFLYRS ETMIKWTR N++
Sbjct: 1494 HSELLCYLIIVLNNVVSASVISVVLPILVFLWAMLALPRPSKRFWMTAIVYTEVMVVLKYIFQFGFFSWNSAHEMTVNKDRPFFPPRILGLEKTDNYLRYDLLQLLALFFHRALLMVCTLNLKSFRPDQEALLAKAAALRKKEALVPEEIHLRAKEEEEEMRLRAKKEQLELETDLTVASARLKVYESLKDVQSSPAQNFFKNLMHNKHQASTDVYALMFLTDMVDFVIIIFGFWAFGKHSAAADIA-STLSEDQVPEAFLVMLLIHFSTMIIDRALYLRKAVLGKLIFQGILVLGIHVWMFFILPSVTERKFNQNFVAQLWYFVKCIYFGLSAYQIRCGYPTRILGNFLTKNFGHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIV-FFLICIIWFPLLFISLVRSVVGVVNHPIDVTVTVKLGGYEPLFTMSVQQQSIQPFNNSQYEELTKMFKD-NTAMQFITLYSYEDIVTAQIEGSSGSVWRISPPSRQEVIKELLGSQVDLTLRLAWNFQRDLGKGGTVE----HTFDKYSIDLEPGNLVRAELASLLIGNRTEPVLVPNFFPNYIRAPNGAEAKPVSQLYKGGEDGYLGITLSLKSDRSSNSSGTREWWDI----------AVEGCVPPSCGVLRMVIFNDKVSPPSLGFL-AGYGIMGLYVSVVLVIGKFVRGFFSEISHSIMFEELPCVDRILKLCTDIFLVRETGELELEEELYSKLIFLYRSPETMIKWTRENRA 2270
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Medaka
Match: PIEZO2 (piezo type mechanosensitive ion channel component 2 [Source:NCBI gene;Acc:101174622])

HSP 1 Score: 421.009 bits (1081), Expect = 8.399e-118
Identity = 226/583 (38.77%), Postives = 340/583 (58.32%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEAR-WWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            M++F+  + +P+++   DVYV MFL + + F+II+FG+ +FG    S  +    +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP IT+K+FN     Q+ YFVKCIYF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDTS++L  W+ VED++  IF+LKCWR SE  YP  RG  ++   KY +GG+++       W PL   S + +   V N P++ + +I++ G+ P+F   +++  L ++ K     +    +N++P           D+    + GSS+ +WTI+PPS + L   LRS E   I +    +R  S     E      N   L++  K+NL+  +     +   Q+      FLT  K                +L +  +     +A+ WW    IV         KI ++  + L +++FS++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE + +KLIFLYRS ETMIKWTR
Sbjct: 2053 MKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFG--KHSTADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVLLVFGIHFWMFFILPIITEKRFNENTVAQMWYFVKCIYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTSLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIVVLLICIVWFPLLFMSLVKSVAGVVNAPLDVSVTITLAGFQPIFTMSAQQKQLWNVTKTAIQWL----ENYTPE----------DLIIAELKGSSNSLWTISPPSRDNLIDMLRSQEEFSITVSWSIQRNLSLGAEAES-AYGKNVMVLNQETKQNLILLLNGAADAANTQVI-----FLTGNKMI------------DIHLTMQRAQNDSGQAQEWW----IVNQTEQSIIPKIGRKHEAGLEIYVFSDQVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHKIMFEELPNVDRILKLCTDIFLVRETGELDLEEDMYSKLIFLYRSPETMIKWTR 2596

HSP 2 Score: 401.749 bits (1031), Expect = 6.001e-112
Identity = 332/1291 (25.72%), Postives = 594/1291 (46.01%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHR-WIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHD----------------PELQLIPDKEAVNQT--GSLLTSSVSKHGE-----YQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKL--------------------------------SSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVS---AFIEDVNSAFQIIIEKLK-------QFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSM---DQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQR-KICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLT-SLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTI------DKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVK--SGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQA--QHGK------------------PELNEH---------YLVVRSGDKYLF 4384
             VVVT   G  GII PS+ + VY   FL +CT+W+      T  F+ M + + +YSA H+ +LYL Q +F Q  +   +   R+ G+  +V ++C    +++ ++ R W  ++SP +++ +YY  AT  R W ++            + + +SS     EH                   L +I D      T  G+ L    +++G      Y T   P   +D     +      E S   +         +++ IK   +         ++ + +  ++ S++   IAMMAWS+TY SW++F+ L+ +C LWM+ D R+  +  SP +V Y  ++I++QY + F      E +   +G  V+           P   L+  +  ++ FWL LR  +T+      +++  L+D   +     D +      +  I     S +  +  KYWI +C     FVS +  +V+++I+YM++ +  +  +   + +WR+ +  FW  V++Y+++VL  +YT+QF+     W     +  E L D+GL+ +  S LF  +  P  FL+V I+ + YFH  FL+L                                SS+   L  D  +V P +   +   S   ++      +  +++ S + +++++L        ++F  +   +W   E H  KIV   I+   + E +  N V ++      P+ +   +  +    W  + ++ KM+YQLKT+N   +  +CS   +   +S+      D   W GL+K  +   ++     +L + A    +  HQ  F      + P   IIF + T Q +D  +    K+ IN+ FYK GLE   ++ V V   R+D Y++++   L+  +  +R K  ++IW  Y  FL  +L  +Y +C+G+PP  C+ YP + +   N+ +WL++P +   P    ++ DF   +  ++Q +VF  EN   V    G      +C +L            DF+  + SY+D LK  +F + +W  L I+F TG   I++FC+GY++  F +L  G  ++L+    ++  W+ +I YN FVI  K  L ++ C Y+D ++    CW+I LF + C          +    +  D C   K  +G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++ +  +E   ++++K ++++I  RQ   + GK                  PE ++          + VVRSGD YLF
Sbjct:  247 KVVVTILLGMTGIILPSLTSFVYFSIFLFLCTWWSLCRTFNTLIFSCMCVLMAIYSAGHIIVLYLYQFQFFQESVSPQDEYIRVFGISPIVQSNCSCTWKLSVHSDRKWYHFVSPIMLLVLYYTLATLIRLWLQEP----------IDHLMVSSADTPAEHQLNVPFLLFGNTCAFITETLNVISDDRQNGPTSNGTSLDFMATENGPPCLNFYST---PQYKMDQPEKKE--ECVYEVSLPPEDSAAKETEDEENDIKKKGV-------GAMVKVFHFVMKQSYICALIAMMAWSITYVSWLTFVFLMWSCILWMVRDRRRYAMMSSPFMVAYGNLIIVLQYFWSF------ERAKPVAGFFVEKKN--------PFHSLSSKMLCMLSFWLLLRQTLTERQEKQKEESAGLSDVHVE-----DQKKKGKPYEQDIMHVFGSMVMAVLVKYWIYICGGMFFFVSFEGNIVMYKIIYMMMFLSCVALYQVHFEYWRRILKYFWMSVVIYTMLVLTVVYTFQFDGSKDFWSGMLNVKNESLNDLGLEQFSVSTLFTRIFIPTSFLLVCILHLHYFHDHFLQLTDLQAVIAKEQSTIYRLVDQDGSLPDLTMLSASSVEGVLSEDKPKVFPDQRQSSTDESQHYSAGSEPEPSTEQNLKSKWHLVVDRLTVLFLKFLEYFHKLQLFIWWLLEIHIIKIVSCYIILLTLYEVSLLNFVFLVCWAFALPYSQYRPLASSICTVWTCVIIVCKMLYQLKTINPPPF--DCSYVLSEVKESLLYKIPGDPGNWWGLKKTEDLLGYLRNNLLMLALLAFEVTIYRHQLYFRLRNKLSPPAAPIIFHDITRQHLDMGITYFIKYFINYFFYKFGLETCLLLVVNVIGQRMDFYAMLHAFALIAVMYRRRRKAIAEIWSKYCFFLACMLTFQYFVCIGIPPAACKDYPWSFTTDSNVIKWLYIPDFYKKPDPLFLIYDFMLLLCASMQRQVFEDENKAAVRLIAGDNVE--ICRDLDAASFSVHNPVPDFIHCR-SYLDMLKVIMFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGELLLKPIKKILHYWDFLIAYNIFVITMKNILSILACGYIDSLMENN-CWLIQLFSLSCT---------IKGYVIKLDTCDIPKNEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIRASQVLASRGAELFQATIVKAVKARLEEEHKSVEQLKRQMERIKVRQQKFKRGKDKILSLAQESAEGQPVVQPEEDDDDGMVNPTPTHSVVRSGDYYLF 1481

HSP 3 Score: 116.316 bits (290), Expect = 3.815e-25
Identity = 65/131 (49.62%), Postives = 88/131 (67.18%), Query Frame = 2 
Query: 5663 SLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRV---DPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRD 6046
            +L N+ + +SEFVCY ++I+NHM+S +  SL  P+ +FLWAMLSVPRPSK +W+  I YTE+ IVIKY  QF F  F  + N R+    P +   IIG+EK   Y + DL+QLL +F HR  LK +GLW +
Sbjct: 1793 ALYNMLVAHSEFVCYLVIIINHMVSASCVSLVLPVTIFLWAMLSVPRPSKRYWMTAIVYTEVTIVIKYFCQFGF--FPHSKNYRLYKNAPYYPANIIGVEKKDGYVLYDLVQLLALFFHRSILKCHGLWDE 1921
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Medaka
Match: ENSORLT00000004626.2 (pep primary_assembly:ASM223467v1:7:7477416:7483305:1 gene:ENSORLG00000003710.2 transcript:ENSORLT00000004626.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 385.571 bits (989), Expect = 2.731e-117
Identity = 223/615 (36.26%), Postives = 344/615 (55.93%), Query Frame = 2 
Query: 6098 RNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPS----LEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKS 7927
            R +IK    ++     + S +    +R+F+  + +P+++   DVY  MFL + + F++ I+GY +FG  +  AD   + +  +++P  F+ M++ QF  +I+DRAL+L+K + GK +FQ+  V  IH W+FF LP +T+++FN     QL YFVKCIYF LSAYQ+K GYP RILGNFLT+++NY+NLFLF+G+ +VPFL ELR VMDW+WTDT+++L  W+ VED++  IFVLKCWR SE +YP   G  ++   KY +GG ++       W PL   S + +   V N P+E +  +S+ GY PLF   ++E NL +                     +LM++EA D+    I   +  +W+I+P S    +E+L +      S+ +N++A+ E              HT  K  D+  K  ++  ++ N S    + D     F       L +A+               +  KE + +WW ++E        S+E  PK  HS + + +F+++VS +  G L + +GI+G+Y + + V  + +R F++ IS  I  EELP VDR+L L  +I++VRE     LEE L  KLIFLYRS ETMIK TR   S
Sbjct:    1 RQQIKERMLQAKAAIIEVSLHIYLPIRQFFYDIIHPEYSPVCDVYALMFLIDVVNFIVTIYGYWAFGKYSAVADIT-ESLSEDQVPEAFLVMLLMQFGTMIVDRALYLKKSLLGKCVFQVVLVFGIHFWMFFILPGVTERRFNRNPIAQLWYFVKCIYFGLSAYQIKCGYPNRILGNFLTKNYNYLNLFLFQGFRMVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYANIFVLKCWRESEKKYPHPPGQKKKKVVKYGMGGFIIFALISIIWFPLLFMSLVQSAAGVTNQPVEVSIQLSIAGYEPLFTMSAQEQNLVA-----------SLFLLQSAMQFLMNYEAEDIIVAKIKSDASLLWSISPASRAAMIEELSISSHLNASISMNVEAVGE--------------HT-VKFNDKALKDGIVSMLKGNSSKPSDRPDLQALAFFRPMSIKLQQASG--------------ASDKEAD-QWWVVEE--CSPVLTSSE--PK-CHS-IEIVVFNDKVSPSSLGFL-AGHGIVGLYMSVVLVIGKFVREFFNGISRSIMFEELPCVDRVLKLCTDIFVVRETGEMELEETLFEKLIFLYRSPETMIKMTREKDS 566
[Close]
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Medaka
Match: PIEZO2 (piezo type mechanosensitive ion channel component 2 [Source:NCBI gene;Acc:101174622])

HSP 1 Score: 412.92 bits (1060), Expect = 2.918e-115
Identity = 229/604 (37.91%), Postives = 360/604 (59.60%), Query Frame = 2 
Query: 6173 MRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTF-VKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSS-DSKTT--EKMVRHTNTKQLDENDKKNLLKAIEANQSSYVV--------------QIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKK-ENEA----RWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTR 7915
            M++F+  + +P+++   DVYV MFL + + F+II+FG+ +FG    S  +    +  +++P PF+ M++ QF  +++DRAL+LRK V GK IFQ+  V  IH W+FF LP IT+K+FN     Q+ YFVKCIYF LSAYQ++ GYP R+LGNFLT+ +NY+NLFLF+G+ +VPFL ELR VMDW+WTDTS++L  W+ VED++  IF+LKCWR SE  YP  RG  ++   KY +GG+++       W PL   S + +   V N P++ + +I++ G+ P+F   +++  L ++ K     +    +N++P           D+    + GSS+ +WTI+PPS + L   LRS E   I +    +R  + DS     + ++ HT    L +     ++  +   Q  +V+               +  + PR++ A  +  S+AT++ +  N+  +++ L+M++ +N++     WW    IV         KI ++  + L +++FS++VS    G L + YGI+G+YA+ + V  + +R F+S IS+ I  EELP+VDRIL L  +I+LVRE     LEE + +KLIFLYRS ETMIKWTR
Sbjct: 2167 MKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFG--KHSTADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVLLVFGIHFWMFFILPIITEKRFNENTVAQMWYFVKCIYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTSLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIVVLLICIVWFPLLFMSLVKSVAGVVNAPLDVSVTITLAGFQPIFTMSAQQKQLWNVTKTAIQWL----ENYTPE----------DLIIAELKGSSNSLWTISPPSRDNLIDMLRSQEEFSITVSWSIQRYPNIDSPLMMFDHIIPHTLQLCLKKKKLFYVI-LLNIFQFLFVIFYFIFFKQNLFRKKTLTKLIPRYIRAPSK--SDATSVEQLGNKM-IDIHLTMQRAQNDSGQAQEWW----IVNQTEQSIIPKIGRKHEAGLEIYVFSDQVSPPSLGFL-AGYGIMGLYASVVLVIGKFVREFFSGISHKIMFEELPNVDRILKLCTDIFLVRETGELDLEEDMYSKLIFLYRSPETMIKWTR 2745

HSP 2 Score: 392.119 bits (1006), Expect = 6.395e-109
Identity = 319/1227 (26.00%), Postives = 566/1227 (46.13%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHR-WIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHD----------------PELQLIPDKEAVNQT--GSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMN------------------------------RFLYGDSREVGPFEDNLNIXXX----XXXXXNVSAFIEDVNSAFQIIIEKLKQF------FEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVI-------------GFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQI--DNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXC-TQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLT-SLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTI------DKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVK--SGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEE 4264
             VVVT   G  GII PS+ + VY   FL +CT+W+      T  F+ M + + +YSA H+ +LYL Q +F Q  +   +   R+ G+  +V ++C    +++ ++ R W  ++SP +++ +YY  AT  R W ++            + + +SS     EH                   L +I D      T  G+ L    +++G     F           GD T          DS        ++D  K  +          ++ + +  ++ S++   IAMMAWS+TY SW++F+ L+ +C LWM+ D R+  +  SP +V Y  ++I++QY + F      E +   +G  V+           P   L+  +  ++ FWL LR  +T+      +++  L+D   +     + E      +  I     S +  +  KYWI +C     FVS +  +V+++I+YM++ +  +  +   + +WR+ +  FW  V++Y+++VL  +YT+QF+     W     +  E L D+GL+ +  S LF  +  P  FL+V I+ + YFH  FL+L+ +                               RFL+        F D+L ++T     S     + +F+  +   F + I+   ++        V++ K   +F  H  ++ ++ ++   I +  +C I+L+ L  +               P+ +   +  +    W  + ++ KM+YQLKT+N   +  +CS Y   F   + +I  D   W GL+K  +   ++     +L + A    +  HQ  F      + P   IIF + T Q +D  +    K+ IN+ FYK GLE   ++ V V   R+D Y++++   L+  +   +RK  ++IW  Y  FL  +L  +Y +C+G+PP  C+ YP + +   N+ +WL++P +   P    ++ DF   +  ++Q +VF  EN   V    G      +C +L            DF+  + SY+D LK  +F + +W  L I+F TG   I++FC+GY++  F +L  G  ++L+    ++  W+ +I YN FVI  K  L ++ C Y+D ++    CW+I LF + C            +     D C   K  +G+ WD  CF F++LQR++FM+  F HVV D+      ASRGA L    ++ +++  +L+EE
Sbjct:  192 KVVVTILLGMTGIILPSLTSFVYFSIFLFLCTWWSLCRTFNTLIFSCMCVLMAIYSAGHIIVLYLYQFQFFQESVSPQDEYIRVFGISPIVQSNCSCTWKLSVHSDRKWYHFVSPIMLLVLYYTLATLIRLWLQEP----------IDHLMVSSADTPAEHQLNVPFLLFGNTCAFITETLNVISDDRQNGPTSNGTSLDFMATENGPPCLNFYSTPQYKMDQPGDSTE---------DSAAKETEDEENDIKKKGV--------GAMVKVFHFVMKQSYICALIAMMAWSITYVSWLTFVFLMWSCILWMVRDRRRYAMMSSPFMVAYGNLIIVLQYFWSF------ERAKPVAGFFVEKKN--------PFHSLSSKMLCMLSFWLLLRQTLTERQEKQKEESAGLSDVHVEDQKKKEEEESKEEEEQDIMHVFGSMVMAVLVKYWIYICGGMFFFVSFEGNIVMYKIIYMMMFLSCVALYQVHFEYWRRILKYFWMSVVIYTMLVLTVVYTFQFDGSKDFWSGMLNVKNESLNDLGLEQFSVSTLFTRIFIPTSFLLVCILHLHYFHDHFLQLTDLQAVIAKEQSTIYSHAKVSGRVYLIVNRWVSARFLWHPPSSQFTF-DSLPVATRRWSGSLCLKKMLSFLSKLGFLFLLSIDLKSKWHLVVDRLTVLFLKFLEYF--HKLQLFIWWLLEIHIIKIVSCYIILLTLYEVSLLNFVFLVCWAFALPYSQYRPLASSICTVWTCVIIVCKMLYQLKTINPPPF--DCS-YVCTFTSLLYKIPGDPGNWWGLKKTEDLLGYLRNNLLMLALLAFEVTIYRHQLYFRLRNKLSPPAAPIIFHDITRQHLDMGITYFIKYFINYFFYKFGLETCLLLVVNVIGQRMDFYAMLHAFALIAVMYRRRRKAIAEIWSKYCFFLACMLTFQYFVCIGIPPAACKDYPWSFTTDSNVIKWLYIPDFYKKPDPLFLIYDFMLLLCASMQRQVFEDENKAAVRLIAGDNVE--ICRDLDAASFSVHNPVPDFIHCR-SYLDMLKVIMFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGELLLKPIKKILHYWDFLIAYNIFVITMKNILSILACGYIDSLMENN-CWLIQLFSLSCTI------KGYVIKLASSDTCDIPKNEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIRASQVLASRGAELFQATIVKAVKA-RLEEE 1360

HSP 3 Score: 119.398 bits (298), Expect = 5.797e-26
Identity = 74/166 (44.58%), Postives = 102/166 (61.45%), Query Frame = 2 
Query: 5663 SLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRV---DPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLW-RDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNK 6148
            +L N+ + +SEFVCY ++I+NHM+S +  SL  P+ +FLWAMLSVPRPSK +W+  I YTE+ IVIKY  QF F  F  + N R+    P +   IIG+EK   Y + DL+QLL +F HR  LK +GLW  D  +  ++  + +KE           E SSP S+K
Sbjct: 1904 ALYNMLVAHSEFVCYLVIIINHMVSASCVSLVLPVTIFLWAMLSVPRPSKRYWMTAIVYTEVTIVIKYFCQFGF--FPHSKNYRLYKNAPYYPANIIGVEKKDGYVLYDLVQLLALFFHRSILKCHGLWDEDDPKERKEASVREKES----------EPSSPLSHK 2057
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Medaka
Match: PIEZO2 (piezo type mechanosensitive ion channel component 2 [Source:NCBI gene;Acc:101174622])

HSP 1 Score: 399.823 bits (1026), Expect = 1.786e-114
Identity = 311/1190 (26.13%), Postives = 553/1190 (46.47%), Query Frame = 2 
Query:  845 NVVVT---GFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHR-WIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHD----------------PELQLIPDKEAVNQT--GSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFED------NLNIXXXXXXXXNVS----AFIE----------DVNSAFQIIIEKLK-------QFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQI-------------DNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXC-TQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLT-SLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTI------DKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVK--SGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFAS 4198
             VVVT   G  GII PS+ + VY   FL +CT+W+      T  F+ M + + +YSA H+ +LYL Q +F Q  +   +   R+ G+  +V ++C    +++ ++ R W  ++SP +++ +YY  AT  R W ++            + + +SS     EH                   L +I D      T  G+ L    +++G     F           GD T          DS        ++D  K  +          ++ + +  ++ S++   IAMMAWS+TY SW++F+ L+ +C LWM+ D R+  +  SP +V Y  ++I++QY + F      E +   +G  V+           P   L+  +  ++ FWL LR  +T+      +++  L+D   +     + E      +  I     S +  +  KYWI +C     FVS +  +V+++I+YM++ +  +  +   + +WR+ +  FW  V++Y+++VL  +YT+QF+     W     +  E L D+GL+ +  S LF  +  P  FL+V I+ + YFH  FL+L+ +   +  +   +    D      +L + ++SS    +S    +F+           D+ S + +++++L        ++F  +   +W   E H  KIV   I+   + E +  N V ++      P+ +   +  +    W  + ++ KM+YQLKT+N   +  +CS    +   + D++             D   W GL+K  +   ++     +L + A    +  HQ  F      + P   IIF + T Q +D  +    K+ IN+ FYK GLE   ++ V V   R+D Y++++   L+  +   +RK  ++IW  Y  FL  +L  +Y +C+G+PP  C+ YP + +   N+ +WL++P +   P    ++ DF   +  ++Q +VF  EN   V    G      +C +L            DF+  + SY+D LK  +F + +W  L I+F TG   I++FC+GY++  F +L  G  ++L+    ++  W+ +I YN FVI  K  L ++ C Y+D ++    CW+I LF + C            +     D C   K  +G+ WD  CF F++LQR++FM+  F HVV D+     FAS
Sbjct:  192 KVVVTILLGMTGIILPSLTSFVYFSIFLFLCTWWSLCRTFNTLIFSCMCVLMAIYSAGHIIVLYLYQFQFFQESVSPQDEYIRVFGISPIVQSNCSCTWKLSVHSDRKWYHFVSPIMLLVLYYTLATLIRLWLQEP----------IDHLMVSSADTPAEHQLNVPFLLFGNTCAFITETLNVISDDRQNGPTSNGTSLDFMATENGPPCLNFYSTPQYKMDQPGDSTE---------DSAAKETEDEENDIKKKGV--------GAMVKVFHFVMKQSYICALIAMMAWSITYVSWLTFVFLMWSCILWMVRDRRRYAMMSSPFMVAYGNLIIVLQYFWSF------ERAKPVAGFFVEKKN--------PFHSLSSKMLCMLSFWLLLRQTLTERQEKQKEESAGLSDVHVEDQKKKEEEESKEEEEQDIMHVFGSMVMAVLVKYWIYICGGMFFFVSFEGNIVMYKIIYMMMFLSCVALYQVHFEYWRRILKYFWMSVVIYTMLVLTVVYTFQFDGSKDFWSGMLNVKNESLNDLGLEQFSVSTLFTRIFIPTSFLLVCILHLHYFHDHFLQLTDLQAVIAKEQSTIYRLVDQDGSLPDLTMLSASSVEGVLSEVRLSFLSKLGFLFLLSIDLKSKWHLVVDRLTVLFLKFLEYFHKLQLFIWWLLEIHIIKIVSCYIILLTLYEVSLLNFVFLVCWAFALPYSQYRPLASSICTVWTCVIIVCKMLYQLKTINPPPF--DCSYVEQSGKYTGDRVSEVKESLLYKIPGDPGNWWGLKKTEDLLGYLRNNLLMLALLAFEVTIYRHQLYFRLRNKLSPPAAPIIFHDITRQHLDMGITYFIKYFINYFFYKFGLETCLLLVVNVIGQRMDFYAMLHAFALIAVMYRRRRKAIAEIWSKYCFFLACMLTFQYFVCIGIPPAACKDYPWSFTTDSNVIKWLYIPDFYKKPDPLFLIYDFMLLLCASMQRQVFEDENKAAVRLIAGDNVE--ICRDLDAASFSVHNPVPDFIHCR-SYLDMLKVIMFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGELLLKPIKKILHYWDFLIAYNIFVITMKNILSILACGYIDSLMENN-CWLIQLFSLSC------TIKGYVIKLASSDTCDIPKNEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIRASGSFAS 1328
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BLAST of Piezo-type mechanosensitive ion channel component vs. Planmine SMEST
Match: SMESG000051188.1 (SMESG000051188.1)

HSP 1 Score: 5103.11 bits (13236), Expect = 0.000e+0
Identity = 2617/2636 (99.28%), Postives = 2621/2636 (99.43%), Query Frame = 2 
Query:  104 MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRXXXXXXXXXXXXXXXTVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQ-LIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGDKYLFXXXXXXXXXXXXXXXXXXCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLXXXXXXXXXXXXXXXXXXXXXXXXXXNPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRRKTIHQPYSCQTLRRSNAVVIEDASEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQLSLDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKPAQKDFEDNLLCVPDPESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXXXXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS 8008
            MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIHIRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQ LIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSE+RD+QGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKIIQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRRKTIHQPYSCQTLRRSNAVVIEDASEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQL+LDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEK A             PESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSH+FVNSKNQEEYLKEQEFRRSRSRFFLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS
Sbjct:    1 MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIHIRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSELRDNQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKIIQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRRKTIHQPYSCQTLRRSNAVVIEDASEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQLTLDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKSAH------------PESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHNFVNSKNQEEYLKEQEFRRSRSRFFLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS 2624
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BLAST of Piezo-type mechanosensitive ion channel component vs. Planmine SMEST
Match: SMESG000051188.1 (SMESG000051188.1)

HSP 1 Score: 5080 bits (13176), Expect = 0.000e+0
Identity = 2607/2636 (98.90%), Postives = 2611/2636 (99.05%), Query Frame = 2 
Query:  104 MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRXXXXXXXXXXXXXXXTVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQ-LIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGDKYLFXXXXXXXXXXXXXXXXXXCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLXXXXXXXXXXXXXXXXXXXXXXXXXXNPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRRKTIHQPYSCQTLRRSNAVVIEDASEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQLSLDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKPAQKDFEDNLLCVPDPESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXXXXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS 8008
            MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIHIRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQ LIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSE+RD+QGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKIIQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRR                       SEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQL+LDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEK AQKDFEDNLLCVPDPESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSH+FVNSKNQEEYLKEQEFRRSRSRFFLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS
Sbjct:    1 MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIHIRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSELRDNQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKIIQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRR-----------------------SEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQLTLDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKSAQKDFEDNLLCVPDPESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHNFVNSKNQEEYLKEQEFRRSRSRFFLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS 2613
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BLAST of Piezo-type mechanosensitive ion channel component vs. Planmine SMEST
Match: SMESG000051188.1 (SMESG000051188.1)

HSP 1 Score: 5048.41 bits (13094), Expect = 0.000e+0
Identity = 2594/2635 (98.44%), Postives = 2598/2635 (98.60%), Query Frame = 2 
Query:  104 MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRXXXXXXXXXXXXXXXTVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGDKYLFXXXXXXXXXXXXXXXXXXCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLXXXXXXXXXXXXXXXXXXXXXXXXXXNPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRRKTIHQPYSCQTLRRSNAVVIEDASEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQLSLDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKPAQKDFEDNLLCVPDPESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXXXXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS 8008
            MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIHIRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSE+RD+QGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKIIQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRR                       SEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQL+LDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEK A             PESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSH+FVNSKNQEEYLKEQEFRRSRSRFFLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS
Sbjct:    1 MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIHIRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSELRDNQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKIIQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRR-----------------------SEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQLTLDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKSAH------------PESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHNFVNSKNQEEYLKEQEFRRSRSRFFLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS 2600
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BLAST of Piezo-type mechanosensitive ion channel component vs. Planmine SMEST
Match: SMESG000051188.1 (SMESG000051188.1)

HSP 1 Score: 5043.79 bits (13082), Expect = 0.000e+0
Identity = 2594/2640 (98.26%), Postives = 2598/2640 (98.41%), Query Frame = 2 
Query:  104 MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRXXXXXXXXXXXXXXXTVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQL-----IPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGDKYLFXXXXXXXXXXXXXXXXXXCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLXXXXXXXXXXXXXXXXXXXXXXXXXXNPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRRKTIHQPYSCQTLRRSNAVVIEDASEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQLSLDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKPAQKDFEDNLLCVPDPESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXXXXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS 8008
            MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIHIRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQL     IPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSE+RD+QGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKIIQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRR                       SEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQL+LDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEK A             PESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSH+FVNSKNQEEYLKEQEFRRSRSRFFLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS
Sbjct:    1 MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIHIRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQLYFQQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSELRDNQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKIIQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRR-----------------------SEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQLTLDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKSAH------------PESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHNFVNSKNQEEYLKEQEFRRSRSRFFLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS 2605
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BLAST of Piezo-type mechanosensitive ion channel component vs. Planmine SMEST
Match: SMESG000051188.1 (SMESG000051188.1)

HSP 1 Score: 5003.34 bits (12977), Expect = 0.000e+0
Identity = 2579/2636 (97.84%), Postives = 2583/2636 (97.99%), Query Frame = 2 
Query:  104 MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRXXXXXXXXXXXXXXXTVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQ-LIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPXXXXXXXXXXXRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNIXXXXXXXXNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDXXXXXXXXXXXXXXCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLXXXXXXXXXXXQRQAQHGKPELNEHYLVVRSGDKYLFXXXXXXXXXXXXXXXXXXCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLXXXXXXXXXXXXXXXXXXXXXXXXXXNPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVGLDIHGSRQTRRKTIHQPYSCQTLRRSNAVVIEDASEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQLSLDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKPAQKDFEDNLLCVPDPESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEXXXXXXXXXLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAXXXXXXXXXXXXHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS 8008
            MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIHIRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQ LIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSE+RD+QGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKIIQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESM                                      SEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQL+LDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEK A             PESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSH+FVNSKNQEEYLKEQEFRRSRSRFFLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS
Sbjct:    1 MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIHIRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQIGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDKQSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNILSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVVVTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYSAIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTHRWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQSNEHDPELQQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAGDITNVGNEFSELRDNQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTAIRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPLIVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGPLAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYFGNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLLLVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWKNKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLKLSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIEKLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVIGFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNFNKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYKCPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTVIVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAICVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVALQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLKHAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRSNLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQCINPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNFCHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKIIQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKMTVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISESRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPLHLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESM--------------------------------------SEHDELSSLPDAYNTPPPAHISETTTEDSFHSAAIQDNQLTNDQAQLTLDLYSANTPESEKYLNPLIYRDTNISSNSVPELISNDETDKKIEKSAH------------PESCWSKFKASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSKISNEVDGRIELEAIVVEIVGDGSHNFVNSKNQEEYLKEQEFRRSRSRFFLLAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPRPSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIEKSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRNKIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCEFIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIIIDRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLYFVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYELRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTRRLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGGYSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQISIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEKMVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSEATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSHSNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISYIIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMIKWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS 2586
The following BLAST results are available for this feature:
BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PIEZO13.752e-13026.51piezo type mechanosensitive ion channel component ... [more]
PIEZO26.837e-12538.44piezo type mechanosensitive ion channel component ... [more]
PIEZO28.165e-12538.44piezo type mechanosensitive ion channel component ... [more]
PIEZO28.194e-12538.44piezo type mechanosensitive ion channel component ... [more]
PIEZO21.017e-6650.46piezo type mechanosensitive ion channel component ... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pezo-18.186e-10628.63Piezo-type mechanosensitive ion channel component ... [more]
pezo-11.391e-10128.74Piezo-type mechanosensitive ion channel component ... [more]
pezo-11.541e-10128.74Piezo-type mechanosensitive ion channel component ... [more]
pezo-11.541e-10128.74Piezo-type mechanosensitive ion channel component ... [more]
pezo-11.866e-10128.74Piezo-type mechanosensitive ion channel component ... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Piezo5.692e-13932.49gene:FBgn0264953 transcript:FBtr0335181[more]
Piezo9.330e-13934.58gene:FBgn0264953 transcript:FBtr0347414[more]
Piezo1.045e-13832.82gene:FBgn0264953 transcript:FBtr0335183[more]
Piezo1.178e-13834.58gene:FBgn0264953 transcript:FBtr0335180[more]
Piezo1.509e-13834.70gene:FBgn0264953 transcript:FBtr0347415[more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
piezo2a.22.771e-13639.15piezo-type mechanosensitive ion channel component ... [more]
LO018508.13.894e-13640.58pep chromosome:GRCz11:2:54327160:54353625:1 gene:E... [more]
piezo17.388e-13128.56piezo-type mechanosensitive ion channel component ... [more]
piezo2a.21.227e-12639.29piezo-type mechanosensitive ion channel component ... [more]
CU179656.11.333e-10925.63pep chromosome:GRCz11:2:54086436:54270366:1 gene:E... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PIEZO21.310e-15638.39piezo-type mechanosensitive ion channel component ... [more]
PIEZO21.853e-15637.73piezo-type mechanosensitive ion channel component ... [more]
PIEZO21.351e-15339.45piezo-type mechanosensitive ion channel component ... [more]
chordc18.771e-14336.74cysteine and histidine rich domain containing 1 [S... [more]
chordc19.703e-14336.74cysteine and histidine rich domain containing 1 [S... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Piezo26.911e-12438.58piezo-type mechanosensitive ion channel component ... [more]
Piezo26.914e-12438.64piezo-type mechanosensitive ion channel component ... [more]
Piezo27.546e-12438.58piezo-type mechanosensitive ion channel component ... [more]
Piezo12.815e-12228.93piezo-type mechanosensitive ion channel component ... [more]
Piezo12.942e-12228.93piezo-type mechanosensitive ion channel component ... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|M9MSG8|PIEZO_DROME2.470e-13734.70Piezo-type mechanosensitive ion channel component ... [more]
sp|Q92508|PIEZ1_HUMAN1.802e-12926.51Piezo-type mechanosensitive ion channel component ... [more]
sp|Q9H5I5|PIEZ2_HUMAN3.921e-12438.44Piezo-type mechanosensitive ion channel component ... [more]
sp|Q8CD54|PIEZ2_MOUSE5.591e-12338.58Piezo-type mechanosensitive ion channel component ... [more]
sp|E2JF22|PIEZ1_MOUSE2.798e-12128.84Piezo-type mechanosensitive ion channel component ... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Z2DRN60.000e+042.96Piezo-type mechanosensitive ion channel component ... [more]
A0A419QG606.327e-3952.43Piezo-type mechanosensitive ion channel component ... [more]
A0A4S2LHK52.348e-5052.22Piezo-type mechanosensitive ion channel component ... [more]
A0A4S2LHI22.612e-5052.22Piezo-type mechanosensitive ion channel component ... [more]
A0A074ZBD71.468e-17752.01Piezo-type mechanosensitive ion channel component ... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
piezo2a.22.447e-13039.90piezo-type mechanosensitive ion channel component ... [more]
piezo2a.22.046e-12840.07piezo-type mechanosensitive ion channel component ... [more]
PIEZO24.703e-12640.68piezo type mechanosensitive ion channel component ... [more]
piezo17.167e-12528.73piezo-type mechanosensitive ion channel component ... [more]
piezo13.475e-1524.26piezo-type mechanosensitive ion channel component ... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000009619.11.860e-3236.27pep scaffold:Pmarinus_7.0:GL484020:1370:4517:1 gen... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO302921.996e-6838.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO473714.054e-4931.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO473704.502e-4030.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO473721.550e-2839.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO473691.416e-2248.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
piezo12.426e-13729.17piezo type mechanosensitive ion channel component ... [more]
PIEZO28.399e-11838.77piezo type mechanosensitive ion channel component ... [more]
ENSORLT00000004626.22.731e-11736.26pep primary_assembly:ASM223467v1:7:7477416:7483305... [more]
PIEZO22.918e-11537.91piezo type mechanosensitive ion channel component ... [more]
PIEZO21.786e-11426.13piezo type mechanosensitive ion channel component ... [more]
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BLAST of Piezo-type mechanosensitive ion channel component vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000051188.10.000e+099.28SMESG000051188.1[more]
SMESG000051188.10.000e+098.90SMESG000051188.1[more]
SMESG000051188.10.000e+098.44SMESG000051188.1[more]
SMESG000051188.10.000e+098.26SMESG000051188.1[more]
SMESG000051188.10.000e+097.84SMESG000051188.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023379 ID=SMED30023379|Name=Piezo-type mechanosensitive ion channel component|organism=Schmidtea mediterranea sexual|type=transcript|length=8264bp
TAACTTTAATTTATTAAAAAATATATTATTTCTAATCTAATTTCAATATT
TTAATTTTAATTAAGATGCTATTACTGTATCTATTTGAAATCGTTTTCAT
GTCATGAGTTGGGTAACATTCGACTATATACTACTGAGAGGATTTCTTCC
AGTTTGTTTGCTAGGATCTACCATAACCAGATACAATGGATTTTCATTCA
TATATCTACTCCTCTTATTAGTTTGTCCCTTTATTAGATATAATCGAATT
CATATCCGAATACCCATACAAATATTTTTAATTATTTTAATAACAGTTAG
TGGGTTATTTTCGCTATCGATTTCATTATTTCACATTCCATTAATATTCA
ATCCATTATTTTTATCCAATTGTACTGATAAATTAACAAGTATATCACAC
CAAATCGGGATAACAAATTTAAAAGGAGTGTTGTTTTATCGAGTTGTAAG
ACTAGTGTTACCGGATTACGTGACTTTAATAACCAGTATTGTGCTACTAA
TTTATTTTCGTAAATACACAACGAAAAGCTATCAAGTTCCAATACATGAT
AAACAATCACAAGAGGATAATCATAATAATGTGATCTCAGATGATGGACA
TACCCCCGATTCTTTATTGCCTGGTCCTAGTCGACCTCTGAAACGACTTA
CTGAAGATACAACTACAGAAACATCTTTTCTTCAACATGAAAGTGGAAAC
ATTTTATCTGAAAACAATGCCGAACATCATCAAAGCAGAAAAATACATGA
CAATCATAACTATTTGCACGACACCCTCGGAATTGATCGTTTACAGAAAA
AAATCTGGAGAGCATGGGCAATGCAAAGTCTATTTGTATTTTTTAATGTG
GTTGTTACCGGATTTGCTGGCATTATATCTCCATCCATTTTGAATTCTGT
TTATCTTTTTGGATTTCTCGGAATATGCACATTTTGGGCTTGTGGAAATA
AAGTTATCACAACTAATTTTGCATATATGCGGATATTTCTTCTCATGTAT
TCGGCTATTCACGTGTGCTTGCTATATTTGGTTCAAATAGAATTCGTACA
ATATTATCTGCCGAATAATAATTTTTCATCCAGACTACTCGGTTTATATT
ATTTGGTTAATACTTCTTGTCAAACAAGAGGAGAGGTCAACTTTTATACC
CATAGATGGATTGATTATTTATCTCCGTGTATCATCATGTATGTTTATTA
TTTATGTGCCACTGAAACTAGGCGGTGGTTTGAAAAAGGTAGAGAGTCGG
TCCCTCGTGTACGATCCTACAAAGAAGATATTAAAATGAGTTCCCTGAAA
CAATCTAATGAACATGATCCAGAATTACAACTTATCCCTGATAAAGAGGC
AGTGAATCAAACTGGAAGTTTACTGACCTCGAGCGTATCAAAACATGGAG
AATATCAAACAATTTTTAGACCTAATCAAACTCTGGATTCTAAAGCAGCC
GGTGACATTACTAATGTGGGAAATGAATTTTCTGAAATTCGAGATAGTCA
AGGTCCTTCGATGGCTGTACTTGATGATGATAGAATCAAATCACCATTGC
TTATCCCGACCCCAACTGAACGCCCGTTGCTCCTCAGTATTATAAACACG
GCAATTCGGAATAGTTTTGTTTTTACTTTTATTGCCATGATGGCATGGAG
CGTGACATATAAATCTTGGATGTCATTTATTCTTCTATTATCAGCTTGCT
ATCTATGGATGATGCCTGACTCAAGAAAAGCTTGTTTGTATATGAGTCCA
TTAATTGTGTTTTATGCTACTGTTTTGATTATAATCCAATACATATATGG
TTTTAATTTGACTGAATTACCAGAATTTTCATATACAGCCAGCGGATCTA
CAGTAGATCTTTCGGAAATCGGATTTCACAAGTGGGCAATTCCTACCGGA
CCTTTAGCAGTAATGATTAGTTTCTTGGTTATATTTTGGCTGACTTTGCG
TCTTTTCATGACTGATACCCTGTTGAATGCATCAAAGCAAAATGAGATTT
TAAATGATTCAAAATTTGATCAAAGTAGCAATGCAGATTCTGAAGCATAT
TTCGGCAATGTTGACAACATGATCTATAAAAAAATTGTATCCTTTTTAAA
TGGAATTTGTGAAAAATATTGGATTCTTGTCTGCTGCTTTGCAATGCTAT
TTGTCTCTATCCAAGAACCGGTAGTTGTATTTCGGATAGTTTATATGCTT
TTGCTAGTCTATTTCCTCATGACATTTATGTTTTCTTATTCATTCTGGAG
AAAGCAGATGTACGTTTTTTGGTGGTTTGTTATTGTCTACAGCGTCATTG
TTCTTCTGTGCATTTACACATATCAATTTAATCAGTTCCCATACCTTTGG
AAAAATAAAACTGGATTATCTGAAGAAATTTTACAAGACATAGGGTTGAA
AACGTACGAAGCATCTGATTTATTTAAAGGTCTTCTGACACCAGTTGTCT
TTCTTGTTGTAATTATTGTTCAAGTTCGATATTTCCACAAACCGTTTCTT
AAATTGTCATCAATGAATAGATTTCTATATGGTGACAGCAGAGAAGTTGG
TCCTTTTGAAGATAATTTAAATATTTCAACATCAAGCTCTTCTACTTCAA
ATGTTTCTGCATTTATCGAAGATGTCAACAGTGCCTTTCAAATCATTATA
GAAAAATTGAAACAATTTTTTGAAGTTATATATGCGAAAGTTTGGAGATT
TTTTGAATGCCACTTTACGAAAATTGTCGTATTTTGTATTGTTTCTGCAT
GTATAAATGAAGAAAATGCCTGCAACATAGTTTTGATCATACTTGTTGTT
ATTGGATTTCCCTTCCATAAGCTCCATACAATCCTAGTAACCGGATCATT
CTTTTGGTGTTCATTGACAGTGTTAATGAAGATGATATACCAGCTCAAAA
CAGTTAATAAATTCAATTGGTCAACAAATTGTTCTTTATATACAACAAAT
TTTAACAAATCAATGGATCAAATTGATAATGCAAAGTGGATAGGATTAGA
GAAAGTAAACAACTTTCAAGACCATATTTGGAAATGGACTGCTGTATTAG
TTGTTTGTGCCCTGTGGCATGTTGTAAAATATCATCAACGGCAATTTTAT
AAATGTCCAAACGCTACAAAACCCGAAACCGGAATCATTTTCCCTGAAAC
TACAGTGCAAAGCATCGATGATAGTTTAATAAATTTATTTAAATTCTGCA
TAAATTTTGCTTTTTACAAACTTGGACTTGAATTGAGTTTTATCGTCACG
GTTATCGTTGCATGTTTACGAGTTGATGTTTATTCACTTGTTTATTTAAT
ATTACTTCTCATTTTTCTCTGCACACAAAGGAAAATATGTTCGAAAATTT
GGCTGCCATATATGCTGTTTTTAGGCGTTTTACTTCCGATTGAATATGCT
ATTTGTGTTGGACTGCCACCTGGACTCTGTCAAAAATATCCATTAACAAG
TCTTAAAGAAAATCTTCAAAGATGGCTCTTTTTACCAAGTTATGAATATC
CTCCTTCTGCTAAAAAAATAATGGCGGACTTCTTTCAATTTGTATTTGTG
GCTCTTCAGTACAGAGTATTTATAATTGAAAATTCACTTACTGTTAACAA
TTACGGTGGTGGAAGGAACCGACCTATTCTCTGCAATGAATTGCCAAAGA
CTATCGATAAAGATTTTGTCAGCACTAAAGATTCCTACGTTGATTATTTG
AAACATGCAATATTTTATTGGTCATATTGGCTGAGTTTGGCAATTGTTTT
TACAACTGGTGTTTTTTGGATAACTTTATTTTGTCTGGGTTATATGATTT
TGGCATTTATTTATCTATGGATGGGTCAAAATATCATGCTTCGCAAAAGA
AGCAATCTCATCGCATCTTGGAATGTTATTATCTATTACAATTTTTTCGT
TATCCTGTCAAAATGTACTCTTCAATTAATTGGATGCGCCTATATGGATT
GGATGATAAGCAAAAGGTTCTGTTGGATGATTCCATTATTTGGCGTGCAA
TGCATCAATCCAATGTCTTGGGATAGAAATATGCTAGCTGTTAACCGAAT
GCATGGAGATCCTTGCTCTTCAGTCAAAAGCGGATTACATTGGGATGTTA
CCTGTTTTCTTTTTATAATATTACAACGAAAGATATTTATGACTAAAAAT
TTTTGTCATGTTGTGCTAGATCTCAATGTCCAAAATAGATTTGCTTCTAG
AGGAGCTTATTTGATTAATAGGAAAATGATGGCATCTATCCGGGAACAAA
AATTGAAAGAAGAATGTGTTTTGGATAAAATTAAAATGAAAATTGATAAA
ATCATTCAACGCCAAGCTCAACACGGGAAACCAGAATTGAATGAACACTA
TTTAGTTGTTCGATCCGGTGATAAATACCTTTTTGAGGGTGACTCTGATG
AAGATGATGAAGATGTAGAGGGAGATATTGATGAATCTTGTTCAAAAAAA
ATGACAGTTACATCTGAAGATACGTTTGATAAAAACACATCAAACAACCA
AAATAAAAAATGTTCAGTGGATTCTTTGGATTCACAAGGATTGTTTAATG
CTGTTAATGTTGTTACAAGTCATTCCAGAAATTTACTAAAGCCCATTAGT
GAAAGTAGATGTTCAACAGAGTCATCGCGCAAGAGTTTGGATAATCAAAA
TAAAATTATAAAGGAAATAAATAAAAAGGATGCCAAAGACTCAGATAGCT
CTGAAGAAGATGATGCTAACCCGCTTCAAGTTCAAAATACTATAAATCCA
CTTCATTTAATAAATAGGGCTATGGAACAAGGACCTAGATCTGCTATTCG
AGAATTTAAACGAACTCAATCCGAATGCAAAGAAAATTTACCGTCGAATC
GTCGATCCAGTGTACACTTAGGAAGTCGGTTAGAATCAATGTCGTCTGTT
GGATTGGATATTCACGGTTCTAGGCAAACAAGACGAAAAACTATTCACCA
ACCTTACTCATGCCAGACATTACGTCGGTCTAATGCTGTCGTTATTGAAG
ATGCGTCTGAGCACGATGAGTTAAGCTCATTACCAGATGCTTACAATACT
CCACCTCCTGCACATATTTCTGAAACTACTACCGAAGATTCCTTTCATTC
TGCAGCAATTCAAGATAATCAGTTGACCAATGACCAAGCCCAACTGAGTT
TAGATTTATATTCCGCTAATACGCCTGAAAGTGAAAAATATTTGAATCCG
TTAATCTACAGGGACACCAACATCAGCTCAAACTCTGTGCCGGAATTGAT
TTCTAATGATGAAACCGATAAAAAGATAGAAAAACCAGCGCAAAAGGATT
TTGAAGATAATCTCCTCTGTGTCCCAGATCCCGAAAGCTGTTGGAGTAAA
TTCAAAGCTAGTATTCTAATTGTTTACTACTTCATTCAAACTACGACCGA
TAATTTAATTGTTCTGATAAATACTTGGACCAAGGAATATCGAAGAATCA
GACGTACTTTAGACAATGAAAAACGACTAGTTAAACTCAAAGTATTATCA
AAAATCAGCAATGAAGTTGATGGAAGAATTGAATTAGAAGCAATAGTTGT
AGAAATTGTTGGCGATGGAAGTCATAGTTTTGTCAATTCCAAGAATCAAG
AAGAGTATTTGAAGGAACAGGAATTTCGACGTTCTAGATCGAGGTTCTTT
TTGCTTGCAATATCATTAGGAAATGTCGCAATTATATATTCTGAATTTGT
ATGTTACTTTCTTTTGATTCTAAATCATATGTTGTCTGGGAATTTGTTTT
CTCTGCCATATCCTCTCATGGTATTTTTATGGGCTATGCTTTCAGTTCCT
CGGCCATCCAAAAACTTTTGGATTGCATTAATTACTTATACGGAGATAGT
GATCGTAATCAAATATATTTTTCAATTCAATTTTATCAGTTTTAATGAAA
CTACCAACGACCGAGTTGATCCTTTGTGGATTCCCCTTATAATTGGCATT
GAAAAATCTAAAAATTATGCTATTCTTGATTTAATACAATTGCTTTTTAT
ATTCCTTCATCGTGGATATTTAAAAAATAATGGACTATGGAGAGATCACA
CAGAATTTGCTCAAGATTTGGAAATTGTCGATAAAGAACAGGATGGAAGA
AATAAAATCAAATCCTCATACGAAGAATCTTCTCCGACATCAAACAAATG
GTCCTGTAATCCCATTTATAAAATGAGAAGATTTTATTCGAAAATGACAA
ATCCAAAGTTCAATAAGAAAGTGGATGTTTATGTTTTTATGTTCCTTTGT
GAATTTATCGCATTTCTGATAATTATATTTGGTTATGTTTCATTTGGTCC
TGGGACTGATTCTGCTGATAATGCGTTTGATTTCATTAAAACAAATAAAA
TTCCTGTGCCTTTTATAACAATGATAATTACTCAGTTTGTATTCATTATT
ATTGACAGAGCGCTTTTCCTAAGAAAACAAGTTAAAGGAAAGTTCATATT
TCAAATATTTCATGTCCTATTGATACACGCGTGGCTATTTTTTGCATTAC
CTCACATTACAAAGAAAAAATTTAATTCACAAATAGCTCCTCAACTTTTA
TATTTTGTAAAATGTATTTACTTTGCTCTTTCAGCATACCAAATGAAATC
TGGTTATCCTTTAAGGATTCTTGGAAATTTTTTGACTCGAGATTTTAATT
ATATTAATTTGTTCTTATTCAAAGGATACATGATCGTTCCTTTTCTATAT
GAACTGAGAAATGTCATGGACTGGATGTGGACTGATACGTCGGTTGCCCT
ATTTCACTGGATGGAAGTTGAAGATGTGTTTTGTAAGATATTTGTTCTAA
AATGTTGGAGGCGTTCTGAATTAGAATATCCAACTGTGAGAGGAAACACC
CGACGATTAGCCTCAAAATACAGTGTCGGTGGTTTGCTACTGGCATTTTT
CTTTATTTGTTTTTGGGGTCCGCTCACACTAAGCAGCTTTATTGGAACAA
CATTTGTCAAAAACCCTCCCATAGAATGCACATTTTCAATAAGTGTCGGT
GGATATAGTCCACTATTCTATTTCATTTCCCGTGAAAACAATTTGAAATC
CTTGCCTAAAGATACATTTGATAAAATGAAAGAATGCTATAAAAACTTCT
CGCCCCCGACAGACTATCTCATGAGTTTTGAAGCGGGCGACGTGACACAA
ATATCAATTGATGGCTCTTCCGATGATGTGTGGACAATAACACCTCCAAG
CCTTGAAAAATTGAAAGTAAAGTTACGAAGCACGGAGTCTTTAAAAATTA
ACATGCAAGCTATTTGTGAAAGGCGCTCATCCGATTCTAAAACTACAGAA
AAAATGGTTCGGCATACAAATACTAAACAGTTAGATGAAAATGACAAAAA
AAATTTACTTAAAGCAATTGAGGCTAATCAGAGTTCTTATGTCGTTCAAA
TAGATGCAATATTTCCACGTTTCCTAACTGCCTACAAAAGAACTCTTTCA
GAAGCAACTGCTCTCCTTAAAGATCATAATCAGACTTATCTCAATCTCAC
TTTGTCTATGAAAAAAGAAAATGAAGCCAGATGGTGGGAAATTCAAGAAA
TCGTTGCAGGAGAAACATATTGTTCTAATGAAAAAATTCCTAAACAGAGT
CATTCTAATTTGACTGTATTTATATTCAGTGAAAGAGTTTCTGACAATTT
ATTCGGACATCTATTCAGTAATTATGGAATTATCGGAATGTATGCTGCAT
ATATTTTCGTTGCCCATCGGGTTCTCAGAGCATTTTACTCAGATATATCA
TACATTATCCGATGCGAGGAGTTGCCACATGTTGACAGGATTCTCAATCT
TCTCAATGAAATTTATCTGGTCAGAGAAAATAAAATGTTTCGCTTGGAAG
AGCAGTTGATTGCGAAATTGATATTCTTGTATAGATCTACAGAAACGATG
ATTAAATGGACGCGACATAATAAATCTATTCTTAGTAAAAACATGGAAAA
GACCAAATCTGACGCTATTGATAATGTGAATAATGATAAAGAAATTACAA
TGAGTTCCTGAAGCCCAATTTTTTCTTATTTTCTATGAATTTTCTATGGA
TTTCATTTTACAAAATTATCAATAGATTTGTGCTGATTAATATTTATTGA
AAGATTTCGATTTCAACTATAGAATTTTATTGTTGAAATAAAAATTTTAA
TATTAATTATTATTGATAATATCAATGTCTTTGGCATGCATTTTATTTGA
TTCTATTGTATTATTGATTATTGGAGTTATTGAATTGATGCTTGATTGGA
GAATATTATGAATA
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protein sequence of SMED30023379-orf-1

>SMED30023379-orf-1 ID=SMED30023379-orf-1|Name=SMED30023379-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2636bp
MSWVTFDYILLRGFLPVCLLGSTITRYNGFSFIYLLLLLVCPFIRYNRIH
IRIPIQIFLIILITVSGLFSLSISLFHIPLIFNPLFLSNCTDKLTSISHQ
IGITNLKGVLFYRVVRLVLPDYVTLITSIVLLIYFRKYTTKSYQVPIHDK
QSQEDNHNNVISDDGHTPDSLLPGPSRPLKRLTEDTTTETSFLQHESGNI
LSENNAEHHQSRKIHDNHNYLHDTLGIDRLQKKIWRAWAMQSLFVFFNVV
VTGFAGIISPSILNSVYLFGFLGICTFWACGNKVITTNFAYMRIFLLMYS
AIHVCLLYLVQIEFVQYYLPNNNFSSRLLGLYYLVNTSCQTRGEVNFYTH
RWIDYLSPCIIMYVYYLCATETRRWFEKGRESVPRVRSYKEDIKMSSLKQ
SNEHDPELQLIPDKEAVNQTGSLLTSSVSKHGEYQTIFRPNQTLDSKAAG
DITNVGNEFSEIRDSQGPSMAVLDDDRIKSPLLIPTPTERPLLLSIINTA
IRNSFVFTFIAMMAWSVTYKSWMSFILLLSACYLWMMPDSRKACLYMSPL
IVFYATVLIIIQYIYGFNLTELPEFSYTASGSTVDLSEIGFHKWAIPTGP
LAVMISFLVIFWLTLRLFMTDTLLNASKQNEILNDSKFDQSSNADSEAYF
GNVDNMIYKKIVSFLNGICEKYWILVCCFAMLFVSIQEPVVVFRIVYMLL
LVYFLMTFMFSYSFWRKQMYVFWWFVIVYSVIVLLCIYTYQFNQFPYLWK
NKTGLSEEILQDIGLKTYEASDLFKGLLTPVVFLVVIIVQVRYFHKPFLK
LSSMNRFLYGDSREVGPFEDNLNISTSSSSTSNVSAFIEDVNSAFQIIIE
KLKQFFEVIYAKVWRFFECHFTKIVVFCIVSACINEENACNIVLIILVVI
GFPFHKLHTILVTGSFFWCSLTVLMKMIYQLKTVNKFNWSTNCSLYTTNF
NKSMDQIDNAKWIGLEKVNNFQDHIWKWTAVLVVCALWHVVKYHQRQFYK
CPNATKPETGIIFPETTVQSIDDSLINLFKFCINFAFYKLGLELSFIVTV
IVACLRVDVYSLVYLILLLIFLCTQRKICSKIWLPYMLFLGVLLPIEYAI
CVGLPPGLCQKYPLTSLKENLQRWLFLPSYEYPPSAKKIMADFFQFVFVA
LQYRVFIIENSLTVNNYGGGRNRPILCNELPKTIDKDFVSTKDSYVDYLK
HAIFYWSYWLSLAIVFTTGVFWITLFCLGYMILAFIYLWMGQNIMLRKRS
NLIASWNVIIYYNFFVILSKCTLQLIGCAYMDWMISKRFCWMIPLFGVQC
INPMSWDRNMLAVNRMHGDPCSSVKSGLHWDVTCFLFIILQRKIFMTKNF
CHVVLDLNVQNRFASRGAYLINRKMMASIREQKLKEECVLDKIKMKIDKI
IQRQAQHGKPELNEHYLVVRSGDKYLFEGDSDEDDEDVEGDIDESCSKKM
TVTSEDTFDKNTSNNQNKKCSVDSLDSQGLFNAVNVVTSHSRNLLKPISE
SRCSTESSRKSLDNQNKIIKEINKKDAKDSDSSEEDDANPLQVQNTINPL
HLINRAMEQGPRSAIREFKRTQSECKENLPSNRRSSVHLGSRLESMSSVG
LDIHGSRQTRRKTIHQPYSCQTLRRSNAVVIEDASEHDELSSLPDAYNTP
PPAHISETTTEDSFHSAAIQDNQLTNDQAQLSLDLYSANTPESEKYLNPL
IYRDTNISSNSVPELISNDETDKKIEKPAQKDFEDNLLCVPDPESCWSKF
KASILIVYYFIQTTTDNLIVLINTWTKEYRRIRRTLDNEKRLVKLKVLSK
ISNEVDGRIELEAIVVEIVGDGSHSFVNSKNQEEYLKEQEFRRSRSRFFL
LAISLGNVAIIYSEFVCYFLLILNHMLSGNLFSLPYPLMVFLWAMLSVPR
PSKNFWIALITYTEIVIVIKYIFQFNFISFNETTNDRVDPLWIPLIIGIE
KSKNYAILDLIQLLFIFLHRGYLKNNGLWRDHTEFAQDLEIVDKEQDGRN
KIKSSYEESSPTSNKWSCNPIYKMRRFYSKMTNPKFNKKVDVYVFMFLCE
FIAFLIIIFGYVSFGPGTDSADNAFDFIKTNKIPVPFITMIITQFVFIII
DRALFLRKQVKGKFIFQIFHVLLIHAWLFFALPHITKKKFNSQIAPQLLY
FVKCIYFALSAYQMKSGYPLRILGNFLTRDFNYINLFLFKGYMIVPFLYE
LRNVMDWMWTDTSVALFHWMEVEDVFCKIFVLKCWRRSELEYPTVRGNTR
RLASKYSVGGLLLAFFFICFWGPLTLSSFIGTTFVKNPPIECTFSISVGG
YSPLFYFISRENNLKSLPKDTFDKMKECYKNFSPPTDYLMSFEAGDVTQI
SIDGSSDDVWTITPPSLEKLKVKLRSTESLKINMQAICERRSSDSKTTEK
MVRHTNTKQLDENDKKNLLKAIEANQSSYVVQIDAIFPRFLTAYKRTLSE
ATALLKDHNQTYLNLTLSMKKENEARWWEIQEIVAGETYCSNEKIPKQSH
SNLTVFIFSERVSDNLFGHLFSNYGIIGMYAAYIFVAHRVLRAFYSDISY
IIRCEELPHVDRILNLLNEIYLVRENKMFRLEEQLIAKLIFLYRSTETMI
KWTRHNKSILSKNMEKTKSDAIDNVNNDKEITMSS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0003001lateral region of the whole animal
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR027272Piezo
IPR031334Piezo_RRas-bd_dom
IPR031805Piezo_dom
Vocabulary: molecular function
TermDefinition
GO:0008381mechanically-gated ion channel activity
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0034220ion transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR031334Piezo non-specific cation channel, R-Ras-binding domainPFAMPF12166Piezo_RRas_bdgcoord: 2194..2605
e-value: 1.0E-118
score: 397.4
IPR031805Piezo domainPFAMPF15917PIEZOcoord: 1277..1409
e-value: 4.0E-25
score: 88.7
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1513..1535
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1503..1545
NoneNo IPR availableTMHMMTMhelixcoord: 596..618
NoneNo IPR availableTMHMMTMhelixcoord: 2084..2106
NoneNo IPR availableTMHMMTMhelixcoord: 776..795
NoneNo IPR availableTMHMMTMhelixcoord: 2515..2537
NoneNo IPR availableTMHMMTMhelixcoord: 2113..2135
NoneNo IPR availableTMHMMTMhelixcoord: 1906..1928
NoneNo IPR availableTMHMMTMhelixcoord: 1850..1872
NoneNo IPR availableTMHMMTMhelixcoord: 907..929
NoneNo IPR availableTMHMMTMhelixcoord: 875..897
NoneNo IPR availableTMHMMTMhelixcoord: 974..991
NoneNo IPR availableTMHMMTMhelixcoord: 263..282
NoneNo IPR availableTMHMMTMhelixcoord: 2145..2162
NoneNo IPR availableTMHMMTMhelixcoord: 237..259
NoneNo IPR availableTMHMMTMhelixcoord: 515..537
NoneNo IPR availableTMHMMTMhelixcoord: 57..79
NoneNo IPR availableTMHMMTMhelixcoord: 544..566
NoneNo IPR availableTMHMMTMhelixcoord: 693..715
NoneNo IPR availableTMHMMTMhelixcoord: 1047..1069
NoneNo IPR availableTMHMMTMhelixcoord: 661..683
NoneNo IPR availableTMHMMTMhelixcoord: 1877..1896
NoneNo IPR availableTMHMMTMhelixcoord: 1082..1104
NoneNo IPR availableTMHMMTMhelixcoord: 720..742
NoneNo IPR availableTMHMMTMhelixcoord: 2042..2064
NoneNo IPR availableTMHMMTMhelixcoord: 1205..1239
NoneNo IPR availableTMHMMTMhelixcoord: 289..311
NoneNo IPR availableTMHMMTMhelixcoord: 2258..2280
NoneNo IPR availableTMHMMTMhelixcoord: 22..44
NoneNo IPR availableTMHMMTMhelixcoord: 1259..1281
NoneNo IPR availableTMHMMTMhelixcoord: 113..135
IPR027272Piezo familyPANTHERPTHR13167UNCHARACTERIZEDcoord: 249..2606