V-type proton ATPase subunit G
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30023364 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of V-type proton ATPase subunit G vs. Ensembl Human
Match: ATP6V1G2 (ATPase H+ transporting V1 subunit G2 [Source:HGNC Symbol;Acc:HGNC:862]) HSP 1 Score: 72.0182 bits (175), Expect = 3.054e-16 Identity = 46/115 (40.00%), Postives = 77/115 (66.96%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA+KV +ARK+KA +L++AKE+AQ E+E + E EF++KQ+ GS+ + ++++ T +Q+ + N+E+ + +LL +V D+ VH N+R Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Human
Match: ATP6V1G2 (ATPase H+ transporting V1 subunit G2 [Source:HGNC Symbol;Acc:HGNC:862]) HSP 1 Score: 72.0182 bits (175), Expect = 3.054e-16 Identity = 46/115 (40.00%), Postives = 77/115 (66.96%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA+KV +ARK+KA +L++AKE+AQ E+E + E EF++KQ+ GS+ + ++++ T +Q+ + N+E+ + +LL +V D+ VH N+R Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Human
Match: ATP6V1G2 (ATPase H+ transporting V1 subunit G2 [Source:HGNC Symbol;Acc:HGNC:862]) HSP 1 Score: 72.0182 bits (175), Expect = 3.054e-16 Identity = 46/115 (40.00%), Postives = 77/115 (66.96%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA+KV +ARK+KA +L++AKE+AQ E+E + E EF++KQ+ GS+ + ++++ T +Q+ + N+E+ + +LL +V D+ VH N+R Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Human
Match: ATP6V1G2 (ATPase H+ transporting V1 subunit G2 [Source:HGNC Symbol;Acc:HGNC:862]) HSP 1 Score: 72.0182 bits (175), Expect = 3.054e-16 Identity = 46/115 (40.00%), Postives = 77/115 (66.96%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA+KV +ARK+KA +L++AKE+AQ E+E + E EF++KQ+ GS+ + ++++ T +Q+ + N+E+ + +LL +V D+ VH N+R Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Human
Match: ATP6V1G2 (ATPase H+ transporting V1 subunit G2 [Source:HGNC Symbol;Acc:HGNC:862]) HSP 1 Score: 72.0182 bits (175), Expect = 3.054e-16 Identity = 46/115 (40.00%), Postives = 77/115 (66.96%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA+KV +ARK+KA +L++AKE+AQ E+E + E EF++KQ+ GS+ + ++++ T +Q+ + N+E+ + +LL +V D+ VH N+R Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Celegans
Match: vha-10 (Probable V-type proton ATPase subunit G [Source:UniProtKB/Swiss-Prot;Acc:P91303]) HSP 1 Score: 80.4925 bits (197), Expect = 6.621e-20 Identity = 52/114 (45.61%), Postives = 80/114 (70.18%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNF 413 M S+ GIQ+LLAAEK AA+K+NEARK+K + ++AK++AQ E+E K E EFK +++ G++ED E KI+ +T+ Q++ + + V NK+ I RLL+LV DI+ ++H N Sbjct: 1 MASQTQGIQQLLAAEKRAAEKINEARKRKLQRTKQAKQEAQAEVEKYKQQREAEFKAFEQQYLGTKEDIESKIRRDTEDQISGMKQSVAGNKQAVIVRLLQLVCDIKPELHHNL 114
BLAST of V-type proton ATPase subunit G vs. Ensembl Celegans
Match: vha-10 (Probable V-type proton ATPase subunit G [Source:UniProtKB/Swiss-Prot;Acc:P91303]) HSP 1 Score: 80.4925 bits (197), Expect = 6.621e-20 Identity = 52/114 (45.61%), Postives = 80/114 (70.18%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNF 413 M S+ GIQ+LLAAEK AA+K+NEARK+K + ++AK++AQ E+E K E EFK +++ G++ED E KI+ +T+ Q++ + + V NK+ I RLL+LV DI+ ++H N Sbjct: 1 MASQTQGIQQLLAAEKRAAEKINEARKRKLQRTKQAKQEAQAEVEKYKQQREAEFKAFEQQYLGTKEDIESKIRRDTEDQISGMKQSVAGNKQAVIVRLLQLVCDIKPELHHNL 114
BLAST of V-type proton ATPase subunit G vs. Ensembl Fly
Match: Vha13 (gene:FBgn0283536 transcript:FBtr0346100) HSP 1 Score: 60.8474 bits (146), Expect = 2.462e-12 Identity = 48/114 (42.11%), Postives = 73/114 (64.04%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNF 413 M S+ GIQ+LLAAEK+AA+KV EARK+KA +L++AK++A +EIE + ER FK + K GSRE KI + ++ ++ + T K+ I +L+ V +I +VH N+ Sbjct: 1 MASQTQGIQQLLAAEKKAAEKVAEARKRKARRLKQAKDEATEEIEKFRQERERAFKEFEAKHMGSREGVAAKIDADIRVKLADMDRAIQTRKDPFILEILQYVYNISPEVHKNY 114
BLAST of V-type proton ATPase subunit G vs. Ensembl Fly
Match: Vha13 (gene:FBgn0283536 transcript:FBtr0083804) HSP 1 Score: 60.8474 bits (146), Expect = 2.462e-12 Identity = 48/114 (42.11%), Postives = 73/114 (64.04%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNF 413 M S+ GIQ+LLAAEK+AA+KV EARK+KA +L++AK++A +EIE + ER FK + K GSRE KI + ++ ++ + T K+ I +L+ V +I +VH N+ Sbjct: 1 MASQTQGIQQLLAAEKKAAEKVAEARKRKARRLKQAKDEATEEIEKFRQERERAFKEFEAKHMGSREGVAAKIDADIRVKLADMDRAIQTRKDPFILEILQYVYNISPEVHKNY 114
BLAST of V-type proton ATPase subunit G vs. Ensembl Zebrafish
Match: atp6v1g1 (ATPase H+ transporting V1 subunit G1 [Source:ZFIN;Acc:ZDB-GENE-030131-6965]) HSP 1 Score: 70.8626 bits (172), Expect = 4.872e-16 Identity = 50/115 (43.48%), Postives = 74/115 (64.35%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA+KV EARK+K +L++AKE+AQ EIE + E+EFKTK+ GS + ++ + T +M I NKE + LL++V DI+ ++H N+R Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVAEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKTKEAAALGSHGNSAVEVDKETVDKMGRIQGSYQQNKEAVLGNLLKMVCDIKPEIHANYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Zebrafish
Match: atp6v1g1 (ATPase H+ transporting V1 subunit G1 [Source:ZFIN;Acc:ZDB-GENE-030131-6965]) HSP 1 Score: 70.8626 bits (172), Expect = 4.872e-16 Identity = 50/115 (43.48%), Postives = 74/115 (64.35%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA+KV EARK+K +L++AKE+AQ EIE + E+EFKTK+ GS + ++ + T +M I NKE + LL++V DI+ ++H N+R Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVAEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKTKEAAALGSHGNSAVEVDKETVDKMGRIQGSYQQNKEAVLGNLLKMVCDIKPEIHANYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Xenopus
Match: atp6v1g2 (ATPase H+ transporting V1 subunit G2 [Source:NCBI gene;Acc:780301]) HSP 1 Score: 78.9518 bits (193), Expect = 5.425e-19 Identity = 49/115 (42.61%), Postives = 79/115 (68.70%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 MTS++ GIQ+LL AEK AA++V+EARK+KA +L++AKE+AQ EIE + EREF+ +Q G++ D +++ T + + + G NKE ++RLL LV +++ ++H N+R Sbjct: 1 MTSQSQGIQQLLQAEKRAAERVSEARKRKARRLKQAKEEAQVEIEQYRLEREREFQIQQRTALGTQGDLSSEVEARTRQTLQMVQSSHGKNKEAVLRRLLGLVCNVKAELHPNYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Xenopus
Match: lcmt2 (leucine carboxyl methyltransferase 2 [Source:Xenbase;Acc:XB-GENE-5944136]) HSP 1 Score: 66.6254 bits (161), Expect = 2.869e-14 Identity = 47/115 (40.87%), Postives = 76/115 (66.09%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA++V EARK+K +L++AKE+AQ EIE + E++FK K+ GS ++++ T ++M+ I + N+EK ++ LL V DI+ ++H N+R Sbjct: 1 MASQSAGIQQLLQAEKRAAERVAEARKRKNRRLKQAKEEAQAEIEQYRLQREKDFKAKEAAALGSHGSCLEEVEKETTEKMSIIQQNYAKNREKVLENLLSFVCDIKPEIHLNYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Xenopus
Match: ankrd52 (ankyrin repeat domain 52 [Source:Xenbase;Acc:XB-GENE-1002005]) HSP 1 Score: 55.8398 bits (133), Expect = 3.729e-10 Identity = 42/115 (36.52%), Postives = 72/115 (62.61%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK A K+ EA+K+K +LR+AKE+A +I+ + E +F+ Q + GS+ + KI+E T +++ KE +++LL+L +I+ ++HTNF+ Sbjct: 1 MASQSQGIQQLLQAEKRAKDKLEEAKKRKNKRLRQAKEEATADIDQYRLKREGDFRRIQTSVMGSQGNLAVKIEEQTVEKIQLYSSSFHKYKEGVLQQLLDLAYNIKPELHTNFQ 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Mouse
Match: Atp6v1g3 (ATPase, H+ transporting, lysosomal V1 subunit G3 [Source:MGI Symbol;Acc:MGI:2450548]) HSP 1 Score: 73.559 bits (179), Expect = 4.893e-17 Identity = 49/117 (41.88%), Postives = 77/117 (65.81%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRKT 422 MTS++ GIQ+LL AEK A K++EA+K+K +LR+AKE+A E + + ME++F+ KQ KI GS+ +I+E T +++ E+ E IK+LL +V D++ +VH N+R T Sbjct: 1 MTSQSQGIQQLLQAEKRAKDKLDEAKKRKGKRLRQAKEEAVAETDQYRMQMEKDFRLKQAKIMGSQSHLSDEIEEQTLEKIKELNGSYNKCMESVIKQLLSMVCDMKPEVHVNYRAT 117
BLAST of V-type proton ATPase subunit G vs. Ensembl Mouse
Match: Atp6v1g2 (ATPase, H+ transporting, lysosomal V1 subunit G2 [Source:MGI Symbol;Acc:MGI:1913487]) HSP 1 Score: 70.0922 bits (170), Expect = 1.064e-15 Identity = 46/117 (39.32%), Postives = 78/117 (66.67%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRKT 422 M S+ GIQ+LL AEK AA+KV +ARK+KA +L++AKE+AQ E+E + E+EF++KQ+ GS+ + ++++ T +Q+ + N+E+ + +LL +V ++ VH N+R T Sbjct: 1 MASQTQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREQEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCEVRPQVHPNYRVT 117
BLAST of V-type proton ATPase subunit G vs. Ensembl Mouse
Match: Atp6v1g1 (ATPase, H+ transporting, lysosomal V1 subunit G1 [Source:MGI Symbol;Acc:MGI:1913540]) HSP 1 Score: 68.9366 bits (167), Expect = 3.227e-15 Identity = 47/115 (40.87%), Postives = 74/115 (64.35%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA+KV+EARK+K +L++AKE+AQ EIE + E+EFK K+ GS ++++ T ++MT + N+++ + LL V DI ++H N+R Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSHGSCSSEVEKETREKMTVLQNYFEQNRDEVLDNLLAFVCDIRPEIHENYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Mouse
Match: Atp6v1g2 (ATPase, H+ transporting, lysosomal V1 subunit G2 [Source:MGI Symbol;Acc:MGI:1913487]) HSP 1 Score: 57.3806 bits (137), Expect = 4.925e-11 Identity = 29/89 (32.58%), Postives = 56/89 (62.92%), Query Frame = 3 Query: 156 KANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRKT 422 KA +L++AKE+AQ E+E + E+EF++KQ+ GS+ + ++++ T +Q+ + N+E+ + +LL +V ++ VH N+R T Sbjct: 4 KARRLKQAKEEAQMEVEQYRREREQEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCEVRPQVHPNYRVT 92
BLAST of V-type proton ATPase subunit G vs. Ensembl Mouse
Match: Atp6v1g2 (ATPase, H+ transporting, lysosomal V1 subunit G2 [Source:MGI Symbol;Acc:MGI:1913487]) HSP 1 Score: 43.5134 bits (101), Expect = 5.306e-6 Identity = 21/75 (28.00%), Postives = 44/75 (58.67%), Query Frame = 3 Query: 198 EIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRKT 422 E+E + E+EF++KQ+ GS+ + ++++ T +Q+ + N+E+ + +LL +V ++ VH N+R T Sbjct: 2 EVEQYRREREQEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCEVRPQVHPNYRVT 76
BLAST of V-type proton ATPase subunit G vs. UniProt/SwissProt
Match: sp|Q617N0|VATG_CAEBR (Probable V-type proton ATPase subunit G OS=Caenorhabditis briggsae OX=6238 GN=vha-10 PE=3 SV=1) HSP 1 Score: 80.4925 bits (197), Expect = 7.325e-19 Identity = 52/114 (45.61%), Postives = 81/114 (71.05%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNF 413 M S+ GIQ+LLAAEK AA+K+NEARK+K + ++AK++AQ E+E K E+EFK +++ G++ED E KI+ +T+ Q+ + + V +NK+ I RLL+LV DI+ ++H N Sbjct: 1 MASQTQGIQQLLAAEKRAAEKINEARKRKLQRTKQAKQEAQAEVEKYKQQREQEFKGFEQQYLGTKEDIESKIRRDTEDQINGMKQSVASNKQAVIVRLLQLVCDIKPELHHNL 114
BLAST of V-type proton ATPase subunit G vs. UniProt/SwissProt
Match: sp|P91303|VATG_CAEEL (Probable V-type proton ATPase subunit G OS=Caenorhabditis elegans OX=6239 GN=vha-10 PE=3 SV=1) HSP 1 Score: 80.4925 bits (197), Expect = 8.423e-19 Identity = 52/114 (45.61%), Postives = 80/114 (70.18%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNF 413 M S+ GIQ+LLAAEK AA+K+NEARK+K + ++AK++AQ E+E K E EFK +++ G++ED E KI+ +T+ Q++ + + V NK+ I RLL+LV DI+ ++H N Sbjct: 1 MASQTQGIQQLLAAEKRAAEKINEARKRKLQRTKQAKQEAQAEVEKYKQQREAEFKAFEQQYLGTKEDIESKIRRDTEDQISGMKQSVAGNKQAVIVRLLQLVCDIKPELHHNL 114
BLAST of V-type proton ATPase subunit G vs. UniProt/SwissProt
Match: sp|Q25532|VATG_MANSE (V-type proton ATPase subunit G OS=Manduca sexta OX=7130 PE=3 SV=1) HSP 1 Score: 77.0258 bits (188), Expect = 1.641e-17 Identity = 56/115 (48.70%), Postives = 79/115 (68.70%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S+ GIQ+LLAAEK AA+KV+EARK+KA +L++AKE+AQ E+E + ER+FK + K G+RE KI T ++ E+ +MV T KE IK +L LV DI+ ++H N+R Sbjct: 1 MASQTHGIQQLLAAEKRAAEKVSEARKRKAKRLKQAKEEAQDEVEKYRQERERQFKEFEAKHMGTREGVAAKIDAETRIKIDEMNKMVQTQKEAVIKDVLNLVYDIKPELHINYR 115
BLAST of V-type proton ATPase subunit G vs. UniProt/SwissProt
Match: sp|Q8BMC1|VATG3_MOUSE (V-type proton ATPase subunit G 3 OS=Mus musculus OX=10090 GN=Atp6v1g3 PE=1 SV=1) HSP 1 Score: 73.559 bits (179), Expect = 3.423e-16 Identity = 49/117 (41.88%), Postives = 77/117 (65.81%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRKT 422 MTS++ GIQ+LL AEK A K++EA+K+K +LR+AKE+A E + + ME++F+ KQ KI GS+ +I+E T +++ E+ E IK+LL +V D++ +VH N+R T Sbjct: 1 MTSQSQGIQQLLQAEKRAKDKLDEAKKRKGKRLRQAKEEAVAETDQYRMQMEKDFRLKQAKIMGSQSHLSDEIEEQTLEKIKELNGSYNKCMESVIKQLLSMVCDMKPEVHVNYRAT 117
BLAST of V-type proton ATPase subunit G vs. UniProt/SwissProt
Match: sp|Q9TSV6|VATG2_PIG (V-type proton ATPase subunit G 2 OS=Sus scrofa OX=9823 GN=ATP6V1G2 PE=3 SV=1) HSP 1 Score: 72.0182 bits (175), Expect = 1.123e-15 Identity = 46/115 (40.00%), Postives = 78/115 (67.83%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA+KV +ARK+KA +L++AKE+AQ E+E + E+EF++KQ+ GS+ + ++++ T +Q+ + N+E+ + +LL +V D+ VH N+R Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREQEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYR 115
BLAST of V-type proton ATPase subunit G vs. TrEMBL
Match: A0A267DRM6 (V-type proton ATPase subunit G OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008207g1 PE=3 SV=1) HSP 1 Score: 95.5153 bits (236), Expect = 2.765e-22 Identity = 58/116 (50.00%), Postives = 86/116 (74.14%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRK 419 MT+++ GIQ LL AEK+A +K++EARK K +L++AK++A EI+T K EREFK + +I GSR D E+ ++E T ++++E+ VG NKE+AIKRLLELV D++ VH NF++ Sbjct: 1 MTTQSGGIQMLLQAEKKAKEKIDEARKNKQRRLKQAKQEAAAEIDTFKKEREREFKEHEARILGSRTDSEKLVQEETRQRLSELETSVGQNKEEAIKRLLELVFDVQPKVHDNFKR 116
BLAST of V-type proton ATPase subunit G vs. TrEMBL
Match: R7TGP4 (V-type proton ATPase subunit G OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_150810 PE=3 SV=1) HSP 1 Score: 88.1965 bits (217), Expect = 1.801e-19 Identity = 56/115 (48.70%), Postives = 83/115 (72.17%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S+N IQ+LL AEK AA+KV+EARK+K +L++AKE+AQ EIE K ER+++ +++I GS+ D E KI + T +M E+ + + NKEKA++RLL LV DI+ ++H N+R Sbjct: 1 MASQNTAIQQLLNAEKRAAEKVSEARKRKGKRLKQAKEEAQNEIEGYKQERERQYRQHEQQILGSKGDMESKIDQTTHVKMQELEQNMAANKEKAMQRLLMLVCDIKPELHENYR 115
BLAST of V-type proton ATPase subunit G vs. TrEMBL
Match: A0A0N4T9B1 (V-type proton ATPase subunit G OS=Brugia pahangi OX=6280 GN=BPAG_LOCUS4761 PE=3 SV=1) HSP 1 Score: 87.8113 bits (216), Expect = 3.850e-19 Identity = 56/115 (48.70%), Postives = 84/115 (73.04%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S+ GIQ+LLAAEK AA+K+NEARK+KA +L++AK++AQ EIE +A ER+FK + K G +ED E KIK+ T++ + ++ + V NK++ I RLL+LV DI+ ++H N + Sbjct: 1 MASQTHGIQQLLAAEKRAAEKINEARKRKAQRLKQAKQEAQAEIEKYRAERERQFKEYEHKYLGKKEDIEMKIKQETEESIKQMEKSVAKNKQQVIVRLLQLVCDIQPELHMNLQ 115
BLAST of V-type proton ATPase subunit G vs. TrEMBL
Match: A0A3P6S7F7 (V-type proton ATPase subunit G OS=Litomosoides sigmodontis OX=42156 GN=NLS_LOCUS1567 PE=3 SV=1) HSP 1 Score: 87.4261 bits (215), Expect = 5.264e-19 Identity = 57/114 (50.00%), Postives = 82/114 (71.93%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNF 413 M S+ GIQ+LLAAEK AA+K+NEARK+KA +L++AK++AQ EIE + EREFK ++K G +ED E KIK++T+ + +I + V NK++ I RLL+LV DI ++H N Sbjct: 1 MASQTQGIQQLLAAEKRAAEKINEARKRKAQRLKQAKQEAQAEIEKYRTEREREFKEYEQKYLGKKEDIEMKIKQDTEDNIRQIEKSVAKNKQQVILRLLQLVCDIRPELHINL 114
BLAST of V-type proton ATPase subunit G vs. TrEMBL
Match: A0A0V0XJI7 (V-type proton ATPase subunit G OS=Trichinella pseudospiralis OX=6337 GN=T4A_10031 PE=3 SV=1) HSP 1 Score: 86.6557 bits (213), Expect = 8.569e-19 Identity = 55/115 (47.83%), Postives = 84/115 (73.04%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S+ GIQ+LLAAEK+AA++VNEARK+KA +L++AKE+AQ+EIE + ER+F+ + K GSR+D +KI+ ++M I ++V NKE+ I+ LL+LV D++ ++H N R Sbjct: 1 MASQTTGIQQLLAAEKKAAEQVNEARKRKARRLKQAKEEAQQEIEKYREQRERQFRQYESKHLGSRDDVAQKIETEASQKMERIEKLVSVNKEQVIQLLLKLVCDVKPEIHRNVR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Cavefish
Match: ENSAMXT00000006945.2 (ATPase H+ transporting V1 subunit G1 [Source:NCBI gene;Acc:103024358]) HSP 1 Score: 68.1662 bits (165), Expect = 4.703e-15 Identity = 48/115 (41.74%), Postives = 74/115 (64.35%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 M S++ GIQ+LL AEK AA+KV +ARK+K +L++AKE+AQ EIE + E+EFKTK+ GS + ++ + T +M I N+E + LL++V DI+ ++H N+R Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVADARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKTKEAAALGSHGNSAVEVDKETLDKMKRIETSYHQNREAVLNNLLKMVCDIKPEIHVNYR 115
BLAST of V-type proton ATPase subunit G vs. Ensembl Sea Lamprey
Match: ATP6V1G3 (ATPase H+ transporting V1 subunit G3 [Source:HGNC Symbol;Acc:HGNC:18265]) HSP 1 Score: 74.7146 bits (182), Expect = 3.027e-18 Identity = 49/116 (42.24%), Postives = 79/116 (68.10%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRK 419 MTS++ GIQ+LL AEK A++KV+EARK+K +L++AKE+AQ EI+ + E EF+ KQ+ I GS+ + KI E T ++ + TN+E +K+LL ++ DI+ ++H N+ + Sbjct: 1 MTSQSQGIQQLLQAEKRASEKVSEARKRKTRRLKQAKEEAQAEIDQYRLQRENEFRKKQDSIMGSQGNMSTKIDEETRTRIQTVRGNYQTNREMVLKQLLAIISDIKPEIHQNYHR 116
BLAST of V-type proton ATPase subunit G vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001946.1 (pep scaffold:Pmarinus_7.0:GL491154:964:3249:1 gene:ENSPMAG00000001767.1 transcript:ENSPMAT00000001946.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 61.2326 bits (147), Expect = 2.108e-13 Identity = 30/89 (33.71%), Postives = 55/89 (61.80%), Query Frame = 3 Query: 156 KANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRKT 422 KA +LR+AKE+AQ EIE + + EF+ KQ+ + GS+ D +I+E T ++ + ++ ++RLL +V D+ ++H N+R++ Sbjct: 1 KARRLRQAKEEAQAEIEQYRQQRDAEFRGKQDTVLGSQGDVSARIQEETRGRVHAMHARQREARDPVLRRLLTIVWDVRPEIHGNYRQS 89
BLAST of V-type proton ATPase subunit G vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001947.1 (pep scaffold:Pmarinus_7.0:GL491154:964:1756:1 gene:ENSPMAG00000001767.1 transcript:ENSPMAT00000001947.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 58.5362 bits (140), Expect = 1.762e-12 Identity = 29/86 (33.72%), Postives = 52/86 (60.47%), Query Frame = 3 Query: 156 KANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNF 413 KA +LR+AKE+AQ EIE + + EF+ KQ+ + GS+ D +I+E T ++ + ++ ++RLL +V D+ ++H N+ Sbjct: 1 KARRLRQAKEEAQAEIEQYRQQRDAEFRGKQDTVLGSQGDVSARIQEETRGRVHAMHARQREARDPVLRRLLTIVWDVRPEIHANY 86
BLAST of V-type proton ATPase subunit G vs. Ensembl Nematostella
Match: EDO34520 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP62]) HSP 1 Score: 78.5666 bits (192), Expect = 1.665e-19 Identity = 52/116 (44.83%), Postives = 82/116 (70.69%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRK 419 M S++ GIQ+LL AEK+AA V +ARK+K KL++AKEQA EI+ K+ E++F Q++ GS++D++ KI+E T Q+ ++ + V +K+ I+RLL LV DI+ ++H NFR+ Sbjct: 1 MASQSQGIQQLLVAEKKAADLVADARKRKTKKLKQAKEQAVAEIDNYKSEREKQFLEYQKEHMGSKDDFQAKIEEATKSQLDQMEDDVNQHKDLVIERLLSLVYDIKPELHQNFRQ 116
BLAST of V-type proton ATPase subunit G vs. Ensembl Medaka
Match: atp6v1g1 (V-type proton ATPase subunit G 1 [Source:NCBI gene;Acc:101172700]) HSP 1 Score: 67.3958 bits (163), Expect = 1.942e-14 Identity = 50/119 (42.02%), Postives = 75/119 (63.03%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRKT*V 428 M S++ GIQ+LL AEK AA+KV EARK+K +L++AKE+AQ EIE + E+EFKTK+ GS + ++ +T ++M I + +N+E + LL V DI+ + H + R T V Sbjct: 1 MASQSQGIQQLLQAEKRAAEKVAEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKTKEAAALGSHGNSAVEVDRDTVERMARIQDSYRSNREAVLGELLRRVCDIQPEFHNHSRSTGV 119
BLAST of V-type proton ATPase subunit G vs. Planmine SMEST
Match: SMESG000078548.1 (SMESG000078548.1) HSP 1 Score: 202.986 bits (515), Expect = 3.335e-68 Identity = 117/117 (100.00%), Postives = 117/117 (100.00%), Query Frame = 3 Query: 72 MTSENDGIQXXXXXXXXXXXXVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRKT 422 MTSENDGIQKLLAAEKEAAKKVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRKT Sbjct: 1 MTSENDGIQKLLAAEKEAAKKVNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFRKT 117
BLAST of V-type proton ATPase subunit G vs. Planmine SMEST
Match: SMESG000063458.1 (SMESG000063458.1) HSP 1 Score: 62.3882 bits (150), Expect = 5.752e-13 Identity = 37/94 (39.36%), Postives = 62/94 (65.96%), Query Frame = 3 Query: 135 VNEARKQKANKLRKAKEQAQKEIETEKALMEREFKTKQEKIFGSREDYERKIKENTDKQMTEIVEMVGTNKEKAIKRLLELVLDIEMDVHTNFR 416 +NEARK+K +L++AKE A+ EIE K MER+F T +E+ G++ YE + + DK++ ++ + V ++ A+ LL+ VL+IE +H NF+ Sbjct: 26 INEARKRKQRRLKQAKEDAKSEIEAYKEEMERKFHTLEEEETGNKGQYEGFVNQMMDKELEKLEKSVQQSQHLALNILLDKVLNIETSLHQNFK 119 The following BLAST results are available for this feature:
BLAST of V-type proton ATPase subunit G vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of V-type proton ATPase subunit G vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of V-type proton ATPase subunit G vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of V-type proton ATPase subunit G vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of V-type proton ATPase subunit G vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 3
BLAST of V-type proton ATPase subunit G vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of V-type proton ATPase subunit G vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of V-type proton ATPase subunit G vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of V-type proton ATPase subunit G vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of V-type proton ATPase subunit G vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of V-type proton ATPase subunit G vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of V-type proton ATPase subunit G vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of V-type proton ATPase subunit G vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of V-type proton ATPase subunit G vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30023364 ID=SMED30023364|Name=V-type proton ATPase subunit G|organism=Schmidtea mediterranea sexual|type=transcript|length=501bpback to top protein sequence of SMED30023364-orf-1 >SMED30023364-orf-1 ID=SMED30023364-orf-1|Name=SMED30023364-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=118bp MTSENDGIQKLLAAEKEAAKKVNEARKQKANKLRKAKEQAQKEIETEKALback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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