Transposon Ty3-I Gag-Pol polyprotein

Query: 4447 KRIKDMSHDIEEIVNYKLSK-KYFALQIDESVDISSKAQLLALVRFIDENEIVNQFLCCRELTEHTTGKDIFNCITTYLEKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKEKNPNIISTHCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFPS-------IQTNNVTDIIPAIIEHLTILDEIIACYFSSLKLESYDWIRNPFGTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSNEHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTLTNIKTKKRERLTDLEEEMRVAISYIRPNIGEIC-KTRQAQISH 5766
            +RIKD++ DIEE +  +L     F+LQ+DES D+S  A LL  VR+     I    L C  L  + TG++IFNCI ++++K +I W+ CV +C+D   ++ G I   VTL+K   P   S+HC L+   L  K +P +LK+ LD+ VQI+NYIK+RP Q+R+ K L   M A++ +LLL+TE+R LSRGKVL RL EL+ ELL +  +    +      N  W  +LAYLADIF  LN VN S+QGKN  + T  DK+ +  +K+ +W + + + N  D FP+       I +    DI  AI++HL  L   +  YF  +  ++  W+RNPF         ++   E +I L+++  +K  F+++S   FW  + +E+PS++++A+ + L F+T +LCE GFS     KTK R+RL D    MR+ +S I PNI  IC K  Q   SH
Sbjct:  250 RRIKDLAADIEEELVCRLKICDGFSLQLDESADVSGLAVLLVFVRYRFNKSIEEDLLLCESLQSNATGEEIFNCINSFMQKHEIEWEKCVDVCSDASRAVDGKIAEAVTLIKYVAPESTSSHCLLYRHALAVKIMPTSLKNVLDQAVQIINYIKARPHQSRLLKILCEEMGAQHTALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAF--RLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEEN-FDCFPTLSDFLTEINSTVDKDICSAIVQHLRGLRATLLKYF-PVTNDNNAWVRNPFTVTVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYRKRL-DAAPHMRIRLSNITPNIKRICDKKTQKHCSH 693          

Query: 4034 RQYSDEYISFGFAWTDEKECPIPKCVVCGVELSNSAMFPAKLNRHFTNSHANLVSKNNDYFKRLLGM----QAKQFKGAMTISDKAQIASYKEL*LIALKLKPHTIAESLILPSCCEIV 4378
            R+Y + Y+SFGF +   ++ P  +CV+C   LSNS++ P+KL RH    HA    K+  +FK+ L      +    K   T ++ A  ASY     IAL  + HTI E LI P   ++V
Sbjct:  108 RKYDESYLSFGFTYFGNRDAPHAQCVLCKKILSNSSLAPSKLRRHLETKHAAYKDKDISFFKQHLDSPENNKPPTPKIVNTDNESATEASYNVSYHIALSGEAHTIGELLIKPCAKDVV 226          

Query: 4447 KRIKDMSHDIEEIVNYKLSK-KYFALQIDESVDISSKAQLLALVRFIDENEIVNQFLCCRELTEHTTGKDIFNCITTYLEKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKEKNPNIISTHCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFPS-------IQTNNVTDIIPAIIEHLTILDEIIACYFSSLKLESYDWIRNPFGTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSNEHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTLTNIKTKKRERLTDLEEEMRVAISYIRPNIGEIC-KTRQAQISH 5766
            +RIKD++ DIEE +  +L     F+LQ+DES D+S  A LL  VR+     I    L C  L  + TG++IFNCI ++++K +I W+ CV +C+D   ++ G I   VTL+K   P   S+HC L+   L  K +P +LK+ LD+ VQI+NYIK+RP Q+R+ K L   M A++ +LLL+TE+R LSRGKVL RL EL+ ELL +  +    +      N  W  +LAYLADIF  LN VN S+QGKN  + T  DK+ +  +K+ +W + + + N  D FP+       I +    DI  AI++HL  L   +  YF  +  ++  W+RNPF         ++   E +I L+++  +K  F+++S   FW  + +E+PS++++A+ + L F+T +LCE GFS     KTK R+RL D    MR+ +S I PNI  IC K  Q   SH
Sbjct:  250 RRIKDLAADIEEELVCRLKICDGFSLQLDESADVSGLAVLLVFVRYRFNKSIEEDLLLCESLQSNATGEEIFNCINSFMQKHEIEWEKCVDVCSDASRAVDGKIAEAVTLIKYVAPESTSSHCLLYRHALAVKIMPTSLKNVLDQAVQIINYIKARPHQSRLLKILCEEMGAQHTALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAF--RLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEEN-FDCFPTLSDFLTEINSTVDKDICSAIVQHLRGLRATLLKYF-PVTNDNNAWVRNPFTVTVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYRKRL-DAAPHMRIRLSNITPNIKRICDKKTQKHCSH 693          

Query: 4034 RQYSDEYISFGFAWTDEKECPIPKCVVCGVELSNSAMFPAKLNRHFTNSHANLVSKNNDYFKRLLGM----QAKQFKGAMTISDKAQIASYKEL*LIALKLKPHTIAESLILPSCCEIV 4378
            R+Y + Y+SFGF +   ++ P  +CV+C   LSNS++ P+KL RH    HA    K+  +FK+ L      +    K   T ++ A  ASY     IAL  + HTI E LI P   ++V
Sbjct:  108 RKYDESYLSFGFTYFGNRDAPHAQCVLCKKILSNSSLAPSKLRRHLETKHAAYKDKDISFFKQHLDSPENNKPPTPKIVNTDNESATEASYNVSYHIALSGEAHTIGELLIKPCAKDVV 226          

Query: 4447 KRIKDMSHDIEE--IVNYKLSKKYFALQIDESVDISSKAQLLALVRFIDENEIVNQFLCCRELTEHTTGKDIFNCITTYL-EKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKEKNPNIISTHCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFPSIQT-----NNVTDII---PAIIEHLTILDEIIACYFSSLKLESYD--WIRNPFGTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSN-EHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTLTNIKTKKRERLTDLEEEMRVAISYIRPNIGEICKTRQAQISH 5766
            +RI+++++D+E+  I   KL+K YF+LQ+DE  DI++   LL  VRF  +++I  +F     L  +TT  +++  +  Y+  K  + + FCVG+C+DG  SM G     VT +KE  P   +THCF+H E L  K +   L S L+ +V+IVNYIKS  L +R+F  L  +M+A ++ LLLH EIR LSRGKVL R+ E+++ELL + Q      + + F++  W A+LAYL+DIF   N +N S+QGKN    +  DK+    +K+  WKNRI+  +  DMF ++ T      N  DI      I EHLT L E    YF S +       WI+NPF + + +       +++++ L+T+  LK+ F   ++   FWI  + ++P L++ A+ + L F ++YLCE GFSTL+ IKTK R  L ++   +RVA+S I+P + ++   +QA +SH
Sbjct:  725 RRIQELANDMEDQLIEQIKLAK-YFSLQLDECRDIANMIILLVYVRFEHDDDIKEEFFFSASLPTNTTSSELYEAVKNYIVNKCGLEFKFCVGVCSDGAASMTGKHSEVVTQIKELAPECKTTHCFIHRESLAMKKISAELNSVLNDIVKIVNYIKSNSLNSRLFSLLCDNMEADHKQLLLHAEIRWLSRGKVLSRMFEIRNELLVFLQG-KKPMWSQLFKDVNWTARLAYLSDIFSIFNDLNASMQGKNATYFSMADKVEGQKQKLEAWKNRIS-TDCYDMFHNLTTIINEVGNDLDIAHLRKVISEHLTNLLECFEFYFPSKEDPRIGNLWIQNPFLSSKDNLNLTVTLQDKLLKLATDEGLKISFENTASLPSFWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSL-NIHYPLRVALSSIQPRLDKLTSKKQAHLSH 1174          

Query: 4034 RQYSDEYISFGFAWTDEKECPIPKCVVCGVELSNSAMFPAKLNRHFTNSHANLVSKNNDYFKRL---LGMQAKQFKGAMTISDKAQIASYKEL*LIALKLKPHTIAESLI 4354
            R+Y   YI FGF    + E   P+C++CG  L+N AM P+KL RH  + H  + S+  ++F+R    L  Q KQ      I+  A  ASYK    +A    P+TIAE+L+
Sbjct:  584 RKYDPSYIEFGFVAVIDGEVLKPQCIICGDVLANEAMKPSKLKRHLYSKHKEISSQPKEFFERKSSELKSQPKQVFNVSHINISALRASYKVALPVAKSKTPYTIAETLV 693          

Query: 4377 LKIMFGDAKNEIMKIPLSNDTIKKK 4451
            L+++   A  ++ ++PLSNDTI ++
Sbjct:  702 LEMLGESAAKKVAQVPLSNDTIARR 726          

Query: 4447 KRIKDMSHDIEE--IVNYKLSKKYFALQIDESVDISSKAQLLALVRFIDENEIVNQFLCCRELTEHTTGKDIFNCITTYL-EKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKEKNPNIISTHCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFPSIQT-----NNVTDII---PAIIEHLTILDEIIACYFSSLKLESYD--WIRNPFGTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSN-EHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTLTNIKTKKRERLTDLEEEMRVAISYIRPNIGEICKTRQAQISH 5766
            +RI+++++D+E+  I   KL+K YF+LQ+DE  DI++   LL  VRF  +++I  +F     L  +TT  +++  +  Y+  K  + + FCVG+C+DG  SM G     VT +KE  P   +THCF+H E L  K +   L S L+ +V+IVNYIKS  L +R+F  L  +M+A ++ LLLH EIR LSRGKVL R+ E+++ELL + Q      + + F++  W A+LAYL+DIF   N +N S+QGKN    +  DK+    +K+  WKNRI+  +  DMF ++ T      N  DI      I EHLT L E    YF S +       WI+NPF + + +       +++++ L+T+  LK+ F   ++   FWI  + ++P L++ A+ + L F ++YLCE GFSTL+ IKTK R  L ++   +RVA+S I+P + ++   +QA +SH
Sbjct:  876 RRIQELANDMEDQLIEQIKLAK-YFSLQLDECRDIANMIILLVYVRFEHDDDIKEEFFFSASLPTNTTSSELYEAVKNYIVNKCGLEFKFCVGVCSDGAASMTGKHSEVVTQIKELAPECKTTHCFIHRESLAMKKISAELNSVLNDIVKIVNYIKSNSLNSRLFSLLCDNMEADHKQLLLHAEIRWLSRGKVLSRMFEIRNELLVFLQG-KKPMWSQLFKDVNWTARLAYLSDIFSIFNDLNASMQGKNATYFSMADKVEGQKQKLEAWKNRIS-TDCYDMFHNLTTIINEVGNDLDIAHLRKVISEHLTNLLECFEFYFPSKEDPRIGNLWIQNPFLSSKDNLNLTVTLQDKLLKLATDEGLKISFENTASLPSFWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSL-NIHYPLRVALSSIQPRLDKLTSKKQAHLSH 1325          

Query: 4034 RQYSDEYISFGFAWTDEKECPIPKCVVCGVELSNSAMFPAKLNRHFTNSHANLVSKNNDYFKR---LLGMQAKQFKGAMTISDKAQIASYKEL*LIALKLKPHTIAESLI 4354
            R+Y   YI FGF    + E   P+C++CG  L+N AM P+KL RH  + H  + S+  ++F+R    L  Q KQ      I+  A  ASYK    +A    P+TIAE+L+
Sbjct:  735 RKYDPSYIEFGFVAVIDGEVLKPQCIICGDVLANEAMKPSKLKRHLYSKHKEISSQPKEFFERKSSELKSQPKQVFNVSHINISALRASYKVALPVAKSKTPYTIAETLV 844          

Query: 4377 LKIMFGDAKNEIMKIPLSNDTIKKK 4451
            L+++   A  ++ ++PLSNDTI ++
Sbjct:  853 LEMLGESAAKKVAQVPLSNDTIARR 877          

Query: 4450 RIKDMSHDIEEIV--NYKLSKKYFALQIDESVDISSKAQLLALVRFIDENEIVNQFLCCRELTEHTTGKDIFNCITTYLEKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKEKNPNIISTHCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFPSIQTNNVTD-----IIPAIIEHLTILDEIIACYFSSLKL-ESYDWIRNPF-GTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSNEHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTLTNIKTKKRERLTDLEEEMRVAISYIRPNIGEICKTR 5748
            RI +MS DI + V  + K S     +Q+ E+ D+   +QL+A VR+I E EIV +FL C  L     G D+FN    +  K +I+ D C  +CTDG  SM G     V  VK++ P+I+ THC L+   LV KTLP  L+ AL  VV+++N+IK R    R+F+     +  +Y  LL HTE+R LSRG++L  + E+ +E+  +  + + N  V  FEN  +   LAYLAD+FK+LN ++ S+Q    N +++ +K+ AF +K  +W+ RI K N  + FP ++   V+D     I   I  HL  L      YFS   L E+  WI +PF    +F +    ++ +     ++ + L MEF  M  E FW       P+L+K A+ I + F+T+YLCELGFS+L + KTK R    +L +++RVAIS   P   +I + +
Sbjct:  149 RIDEMSQDILQQVLEDIKASPLKVGIQLAETTDMDDCSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFNLFRDFFLKHKIALDVCGSVCTDGASSMLGENSEFVAYVKKEIPHIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINFIKGRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSN-LVDGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEKRNFTN-FPFLEEIIVSDNEGIFIAAEITLHLQQLSNFFHGYFSIGDLNEASKWILDPFLFNIDFVDDSYLMKNDLAELRASGQIL-MEFETMKLEDFWCAQFTAFPNLAKTALEILMPFATTYLCELGFSSLLHFKTKSRSCF-NLSDDIRVAISKKVPRFSDIIEQK 586          

Query: 4022 MKTNRQYSDEYISFGFAWTDEKE-CPIPKCVVCGVELSNSAMFPAKLNRHFTNSHANLVSKNNDYFKRLLG--MQAKQFK--GAMTISDKAQIASYKEL*LIALKLKPHTIAESLILPSCCEIVK 4381
            M   R++ D+Y+ + F  T E +    P+CV+C    SN+ + P+KL+ HF   H  +   + +  K +     Q++  K  G  +  D    ASY+   L A +  PHT+AE L+ P   EI +
Sbjct:    1 MSKKRKWDDDYVRYWFTCTTEVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAGHDLNSLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKLVKPCALEIAQ 125          

Query:  274 EESIRREMPECWLCHKIGHTKIDCP------IKGKIECWTCHRSGHISRNCPDKKAPRCFGCGKEGHIRRLCQE 477
            ++  + + P C+ C+K GH   +CP          + C+ C+R+GHIS+NCP+  +  C+GCGK GH+RR C E
Sbjct:   88 KDCTQADNPTCYRCNKTGHWVRNCPEAVNERGPTNVSCYKCNRTGHISKNCPE-TSKTCYGCGKSGHLRRECDE 160          

Query:  283 IRREMPECWLCHKIGHTKIDCPIKGKIECWTCHRSGHISRNCPDKKAPRCFGCGKEGHIRRLCQE---------IRCERCSRNGHRSEEC--YTKMRYG 546
            +RR   +C+ C++ GH    CP + +  C+ C+  GHIS++C     P C+ C K GH  R C E         + C +C+R GH S+ C   +K  YG
Sbjct:   50 MRRNREKCYKCNQFGHFARACPEEAE-RCYRCNGIGHISKDCTQADNPTCYRCNKTGHWVRNCPEAVNERGPTNVSCYKCNRTGHISKNCPETSKTCYG 147          

Query:  283 IRREMPE----CWLCHKIGHTKIDCPIKGKIECWTCHRSGHISRNCP---DKKAP---RCFGCGKEGHIRRLCQEIR--CERCSRNGHRSEEC 525
              R  PE    C+ C+ IGH   DC       C+ C+++GH  RNCP   +++ P    C+ C + GHI + C E    C  C ++GH   EC
Sbjct:   66 FARACPEEAERCYRCNGIGHISKDCTQADNPTCYRCNKTGHWVRNCPEAVNERGPTNVSCYKCNRTGHISKNCPETSKTCYGCGKSGHLRREC 158          

Query:  274 EESIRREMPECWLCHKIGHTKIDCP------IKGKIECWTCHRSGHISRNCPDKKAPRCFGCGKEGHIRRLCQE 477
            ++  + + P C+ C+K GH   +CP          + C+ C+R+GHIS+NCP+  +  C+GCGK GH+RR C E
Sbjct:   88 KDCTQADNPTCYRCNKTGHWVRNCPEAVNERGPTNVSCYKCNRTGHISKNCPE-TSKTCYGCGKSGHLRRECDE 160          

Query:  283 IRREMPECWLCHKIGHTKIDCPIKGKIECWTCHRSGHISRNCPDKKAPRCFGCGKEGHIRRLCQE---------IRCERCSRNGHRSEEC--YTKMRYG 546
            +RR   +C+ C++ GH    CP + +  C+ C+  GHIS++C     P C+ C K GH  R C E         + C +C+R GH S+ C   +K  YG
Sbjct:   50 MRRNREKCYKCNQFGHFARACPEEAE-RCYRCNGIGHISKDCTQADNPTCYRCNKTGHWVRNCPEAVNERGPTNVSCYKCNRTGHISKNCPETSKTCYG 147          

Query:  283 IRREMPE----CWLCHKIGHTKIDCPIKGKIECWTCHRSGHISRNCP---DKKAP---RCFGCGKEGHIRRLCQEIR--CERCSRNGHRSEEC 525
              R  PE    C+ C+ IGH   DC       C+ C+++GH  RNCP   +++ P    C+ C + GHI + C E    C  C ++GH   EC
Sbjct:   66 FARACPEEAERCYRCNGIGHISKDCTQADNPTCYRCNKTGHWVRNCPEAVNERGPTNVSCYKCNRTGHISKNCPETSKTCYGCGKSGHLRREC 158          

Query: 1479 IEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQR-DKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGR--RFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIVEEV---RKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPV----KRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQF----RTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKISREKWYGSK-EIPIKEELEEQTRRKFNVGEEVLVKVETRHKGQ-DRY 3662
            +E+ I +     IIR  +SP       V KK+   +R C+D+R LN++T +  +P+P +    + L G+ FF+ +DL NAY+ V +    + KTAF+T  G + +  +PFG++ AP  FQ ++  VL  +  +   VYLDDILI+S S ++H   +  VL+ + E GL +  EKC    + ++FLGHI+S EG++ DP KIQA+ ++  P+  K L+ FLG  N+YRRFI ++++ A  L  L S  S     WS    + F  LK    +APIL  PD  ++F+++ DAS   +GA+LSQR   DGK    AY SH ++  E+ Y I  +ELLAV      ++H+L G    F + TDHK + ++ + K+ + S+   W  +    +  + YR G  +   D +SR   D   +         +G +   +   I    R+ + +G+   +     +  +PE    + ++  H  ++ CH GV +    +K R+    +   +++ V +C +C  +K+   + + P             +  I +D    L  + G    +L ++D++SK     ++ K          +   + R  G P ++  D G  F S   REF ++L   +  SS +H Q+NGQ ER      RT+R L++     +  + W++ L  VE+  N+    +TG SP +   G +        S+  +P      ++ RR +N   + L++V TR K + DR+
Sbjct:  514 MEKYISDSLAAKIIRPSSSPAGAGFFFV-KKKDGSLRPCIDYRGLNSITVKNTYPLPLMSSAFERLQGANFFTKLDLRNAYHLVRIRPGDEWKTAFNTPRGHFEYCVLPFGLSNAPAVFQALVNDVLRDMIDQFIYVYLDDILIFSHSLQEHVQHVRRVLQRLLENGLYVKAEKCVFHAQSVQFLGHIVSVEGMRMDPEKIQAVVDWPTPDSRKALQRFLGFANFYRRFIRNFSQLAAPLTSLTS--SKMPFRWSSAAEAAFSKLKGCFVSAPILIAPDPSRQFVVEVDASEVGVGAILSQRSSSDGKIHPCAYFSHRLSPAERNYDIGNRELLAVKLALEEWRHWLEGSGVPFIVWTDHKNLEYIRSAKR-LNSRQARWALFFGRFNFTISYRPGSKNIKPDALSRL-FDPSDRLSSPDPVLPQGIVVANISWEIESRVRTAL-NGVTPPIGCPPSRLFVPEELRSDVVRWGHSSKVACHPGVSRTLFVIKQRFWWPTMARDVRDFVLACSVCAVSKS---SNRPPAGLLQPLSVPSRPWSHISLDFVTGLPSSNG-NTVVLTVVDRFSKAAHFISLPKLPSARETAVAVIDHVFRIHGLPTDVVSDRGPQFVSRFWREFCRLLGATVSLSSGFHPQSNGQTERANQDLERTLRCLVS-----QNPSSWSQQLSWVEYAHNSLPVSSTGLSPFQCSLGYQPPVFPSLESEVAVPSVHAFVQRCRRTWNRARQTLLRVGTRTKAKADRH 1247          

Query:  897 SITVRMNGENFD--CLLDTGARINVMSVNCFNKLRGQQLTKSDD-KLRCANESTIETI----GKTKVQVTIGNVSKEVIFIVAE-KVTPDVIGGIELQETFGFRLLKIKDIEASEKDKNYICNIEA--KFGRKIKDEERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQR-DKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGR--RFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGK---IKTRL-LDSIREEGRSNIQ---HGIVEE---VRKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPV----KRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKISREKWYGSK-EIPIKEELEEQTRRKFNVGEEVLVKVETRHKGQ-DRY 3662
            ++ +  +  NF    ++D+GA  N +      KLR   ++ S    +   N S++ +I    G  ++ +T GN S+ + F + E  VTP V+G   L         + + + +  +  +  C + A     R +  EE +   L  +   E   LK + + S    +       R +    +++    P   K Y   +     +E+ I +     IIR  +SP       V KK+   +R C+D+R LNA+T +  +P+P +    + L G+ FF+ +DL NAY+ V + E  + KTAF+T  G + +  +PFG++ AP  FQ ++  VL  +  +   VYLDDILI+S S ++H   +  VL+ + E GL +  EKC    + + FLGHI+S EG++ DP K+QA+ ++  P+  K L+ FLG  N+YRRFI ++++ A  L  L S        WS      F+ LK    +APIL  PD  ++F+++ DAS   +GA+LSQR   DGK    AY SH + + E+ Y I  +ELLAV      ++H+L G    F + TDHK + ++ + K+ + S+   W  +    D  + YR G  +   D +SR            H E        +  RL + ++  E  S ++    G+         +  +PE    + I+  H  +L CH GV +    +K R+    +   I+  V +C +C  +K    + + P             +  I +D    L  + G    IL ++D++SK      + K          +   + R  G P ++  D G  F S   REF  ++   +  SS +H Q+NGQ ER  + +  ++   L  +  + W++ L  VE+  N+     TG SP E   G +        S+  +P      ++ RR +N   + L++V  R K + DR+
Sbjct:  344 NVMLEWSSGNFSTQAIIDSGAEGNFIDSALVKKLRLPVISLSQPISVHALNGSSLPSITHSTGPIRL-ITSGNHSEIIHFFLTEAPVTPVVLGHPWLVIHNPHINWRQESVISWSESCHATCLLSACSSVSRSVFQEEHM--DLSNVP-KEYLDLKRVFSKSRAASLPPH----RPYDCAIELLPGTSPPKGKLYSLSVPEREAMEKYISDSLAAKIIRPSSSPAGAGFFFV-KKKDGSLRPCIDYRGLNAITVKNTYPLPLMSSAFERLQGASFFTKLDLRNAYHLVRIREGDEWKTAFNTPRGHFEYCVLPFGLSNAPAVFQALVNDVLRDMLDQFIYVYLDDILIFSHSLQEHVQHVRRVLQRLLENGLYVKAEKCVFHAQSVPFLGHIVSVEGMRMDPEKVQAVVDWPTPDSRKALQRFLGFANFYRRFIRNFSQLAAPLTALTS--LKTPFRWSNAAQVAFDRLKSCFVSAPILIAPDPSRQFVVEVDASEVGVGAILSQRSSSDGKMHPCAYFSHRLNNAEQNYDIGNRELLAVKLALEEWRHWLEGSGVPFIVWTDHKNLEYIQSAKR-LNSRQARWALFFGRFDFSISYRPGSKNVKPDALSRI---------FDHSERASSPETIVPRRLFISAVTWEIESRVRMALEGVTPPPGCPPSRLFVPEELRSDVIRWGHSSKLACHPGVSRTLYLIKQRFWWPVMARDIRNFVLACSVCAVSKT---SNRPPAGLLQPLSVPSRPWSHIALDFVTGLPPSNG-NTVILTVVDRFSKATHFIPLPKLPSARETAAAVIDHVFRIHGLPTDVVSDRGPQFISKFWREFCHLMGATVSLSSGFHPQSNGQTERANQDLERMLRC-LVSQNPSSWSQQLSWVEYAHNSLPVSATGLSPFECSLGYQPPAFPSLESEVAVPSAHAFVQRCRRTWNRARQTLLQVGLRTKAKADRH 1273          

Query: 1479 IEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRD-KDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGR--RFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIVEEV---RKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPV----KRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQF----RTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKISREKWYGSK-EIPIKEELEEQTRRKFNVGEEVLVKVETRHKGQ-DRY 3662
            +E+ I +     IIR  +SP       V KK+   +R C+D+R LN++T +  +P+P +    + L G+ FF+ +DL NAY+ V +    + KTAF+T  G + +  +PFG++ AP  FQ ++  VL  +  +   VYLDDILI+S S ++H   +  VL+ + E GL +  EKC    + ++FLGHI+S EG++ DP KIQA+ N+  P+  K L+ FLG  N+YRRFI ++++ A  L  L S  S     WS    + F  LK    +APIL  PD  ++F+++ DAS   +GA+LSQR   DGK    AY SH ++S E+ Y I  +ELLAV      ++H+L G    F + TDHK + ++ + K+ + S+   W  +    +  + YR G  +   D +SR   D   +         +  +   +   I    R+ +  G+   +     +  +PE    + ++  H  ++ CH GV +    +K R+    +   +++ V +C +C  +K+   + + P             +  I +D    L  + G    IL ++D++SK     ++ K          +   + R  G P ++  D G  F S   REF ++L   +  SS +H Q+NGQ ER      RT+R L++     +  + W++ L  VE+  N+     TG S  +   G +        S+  +P      ++ RR +N   + L++  TR K + DR+
Sbjct:  540 MEKYISDSLAAKIIRPSSSPAGAGFFFV-KKKDGSLRPCIDYRGLNSITVKNTYPLPLMSSAFERLQGANFFTKLDLRNAYHLVCIRPGDEWKTAFNTPRGHFEYCVLPFGLSNAPAVFQALVNDVLRDMIDQFIYVYLDDILIFSHSLQEHIQHVRRVLQRLLENGLYVKAEKCVFHAQSVQFLGHIVSVEGMRMDPEKIQAVVNWPTPDSRKALQRFLGFANFYRRFIHNFSQLAAPLTSLTS--SKTPFRWSSAAEAAFSKLKGCFVSAPILIAPDPSRQFVVEVDASEVGVGAILSQRSASDGKVHPCAYFSHRLSSAERNYDIGNRELLAVKLALEEWRHWLEGSGVPFIVWTDHKNLEYIKSAKR-LNSRQARWALFFGRFNFTISYRPGSKNIKPDALSRL-FDPSDRTSSPDPVLPQRIVVANISWEIESRVRTALD-GVTPPIGCPPNRLFVPEELRSDVVRWGHSSKVACHPGVSRTLFVVKQRFWWPAMARDVRDFVLACSVCAVSKS---SNRPPAGLLQPLSVPSRPWSHISLDFVTGLPSSNG-NTVILTVVDRFSKAAHFISLPKLPSARETAVAVIDHVFRIHGLPTDVVSDRGPQFVSKFWREFCRLLGATVSLSSGFHPQSNGQTERANQDLERTLRCLVS-----QNPSSWSQQLSWVEYAHNSLPVSATGLSSFQCSLGYQPPVFPSLDSEVAVPSVHAFVQRCRRTWNRARQTLLQAGTRTKAKADRH 1273          

Query: 1515 IIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQR-DKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGR--RFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIVEEV---RKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPV----KRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQF----RTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKISREKWYGSK-EIPIKEELEEQTRRKFNVGEEVLVKVETRHKGQ-DRY 3662
            IIR  +SP       V KK+   +R C+D+R LN +T +  +P+P +    + L G+ FF+ +DL NAY+ V +    + K+AF+T  G + +  +PFG++ AP  FQ  +  VL  +  +   VYLDDILI+S S ++H   +  VL+ + E GL +  EKC    + + FLGHI+S EG++ DP KI+A+ N+  P+  K L+ FLG  N+YRRFI ++++ A  L  L S  S     WS    + F  LK    +APIL  PD  ++F+++ DAS   +GA+LSQR   DGK    AY SH +++ E  Y I  +ELLAV      ++H+L G    F + TDHK + ++ + K+ + S+   W  +    +  + YR G  +   D +SR   D+  +         K  + + +   I  + R+ +  G+   +     +  +PE    + I+  H  ++ CH GV + +  +K R+    L   +++ V +C +C  +K    + + P             +  I +D    L  + G    IL ++D++SK      + K          +   + R  G P ++  D G  F S   REF ++L   +  SS +H Q+NGQ ER      RT+R L++     +  + W++ L  VE+  N+     TG SP +   G +        S+  +P      ++ RR ++   + L++V  R K + DR+
Sbjct:  554 IIRPSSSPAGAGFFFV-KKKDGSLRPCIDYRGLNNITVKNTYPLPLMSSAFERLQGANFFTKLDLRNAYHLVRIRAGDEWKSAFNTPRGHFEYCVLPFGLSNAPAVFQAFVNDVLRDMIDQFIYVYLDDILIFSHSLQEHVQHIRRVLQRLLENGLYVKAEKCVFHAQSVPFLGHIVSVEGLRMDPEKIKAVVNWPTPDSRKALQRFLGFANFYRRFIRNFSQLAAPLTALTS--SKTPFRWSSAAEAAFSKLKGCFVSAPILITPDPSRQFVVEVDASEVGVGAILSQRSSSDGKIHPCAYYSHRLSAAESNYDIGNRELLAVKLALEEWRHWLEGSGVPFIVWTDHKNLEYIKSAKR-LNSRQARWALFFGRFNFTISYRPGSKNIKPDALSRL-FDSSERTSSLEPVVPKRIVISNITWEIESKVRAALD-GVTPPIGCPPSRLFVPEKLRSDVIRWGHSSKVACHPGVSRTSFVIKQRFWWPALARDVRDFVLACSVCAVSKT---SNRPPAGLLQPLSVPSRPWSHISLDFVTGLPPSNG-NTVILTVVDRFSKAAHFVPLPKLPSARETAVAVINHVFRIHGLPTDVVSDRGPQFISKFWREFCRLLGATVSLSSGFHPQSNGQTERANQDLERTLRCLVS-----QNPSSWSQQLSWVEYAHNSLPVSATGLSPFQCSLGYQPPVFPSLESEVAVPSVHAFVQRCRRTWSRARQTLLQVGVRTKAKADRH 1275          

Query: 1479 IEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDK-DGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGR--RFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSR-------TKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIVEEV---RKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEM----FEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQF----RTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKISREKWYGSK-EIPIKEELEEQTRRKFNVGEEVLVKVETRHKGQ-DRY 3662
            +E+ I +     IIR  +SP       V KK+   +R C+D+R LN++T +  +P+P +    + L G+ FF+ +DL NAY+ V +    + KTAF+T  G + +  +PFG++ AP  FQ ++  VL  +  +   VYLDDILI+S S ++H   +  VL+ + E GL +  EKC    + ++FLGH +S EG++ DP KIQA+ N+  P+  K L+ FLG  N+YRRFI ++ + A  L  L S  S     WS    + F  LK    +APIL  PD  ++F+++ D S   +GA+LSQR   DGK    AY SH +++ E+ Y I  +ELLAV      ++H+L G    F + TDHK + ++ + K+ + S+   W  +    +  + YR G  +   D +SR       T     V  Q         +I++R+  ++          G+   +     +  +PE+   + I   H  ++ CH GV +    +K R+    +   +++ V +C +C  +K+   + + P        +    +  I +D    L  + G    +L ++D++SK      + K          +   + R  G P ++  D G  F S   REF ++L   +  SS +H Q+NGQ ER      RT+R L++     +  + W++ L  VE+  N+     TG SP +   G +        S+  +P      ++ RR +N   + L++V  R K + DR+
Sbjct:  513 MEKYISDSLAAKIIRPSSSPAGAGFFFV-KKKDGSLRPCIDYRGLNSITVKNTYPLPLMSSAFERLQGANFFTKLDLRNAYHLVRIRPGDEWKTAFNTPRGHFEYCVLPFGLSNAPAVFQALVNDVLRDMIDQFIYVYLDDILIFSHSLQEHVQHVRRVLQRLLENGLYVKAEKCVFHAQSVQFLGHTVSVEGMRMDPEKIQAVVNWPTPDSRKALQRFLGFANFYRRFIRNFRQLAAPLTNLTS--SKTPFRWSNAAEAAFSKLKGCFVSAPILIAPDPSRQFVVEVDVSEVGVGAILSQRSALDGKIHPCAYFSHRLSAAERNYDIGNRELLAVKLALEEWRHWLEGSGVPFIVSTDHKNLEYIKSAKR-LNSRQARWALFFGRFNFSISYRPGSKNIKPDALSRLFDRSDRTSSPDPVLPQRVFVANISWEIESRVRTAL---------DGVTPPIGCPPSRLFVPEDLRSDVIWWGHSSKVACHPGVSRTLFVIKQRFWWPVMARDVRDFVLACSVCAASKS---SNRPPAGLLQPLSVPSRPWSHISLDFVTGLPSSNG-NTVVLTVVDRFSKAAHFVPLPKLPSARETAVAVIDHVFRIHGLPTDVVSDRGPQFVSKFWREFCRLLGATVSLSSGFHPQSNGQTERANQDLERTLRCLVS-----QNPSSWSQQLSWVEYAHNSLPVSATGLSPFQCSLGYQPPVFPSLESEVAVPSIHAFVQRCRRTWNRARQTLLQVGERTKAKADRH 1246          

Query: 1299 EQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGE-PINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVL-GKIKGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSR 2684
            + L +++  +L++I+ +   +F A+    GRTH  +HK+ T  + PI    YR    +  +++  I  +   G+I   +SPW +P++ V KK+    R C+D+R+LN VT   A+PMP +DE+LD LG + + +++DL   Y+Q+ L   +QEK+AF T  G Y F  MPFG+  AP TFQ ++ ++L G    A  YLDDI ++S + E+H   L  V   I++AGL + PEKC +   E+++LGH +    ++ DP+K++AI  +  P   K++ +FLG   YYR+FI +Y+  A+ L  L S   ++ + W+    S    LK AL ++P+L  PD  + FIL TDAS   +GAVLSQ +  G+E  +AY S  +   E  Y    KE LA+ +     + YLYGR FT+ TDH  ++++         +   W   L   +  +++RKG  H NAD +SR
Sbjct:  295 DHLHLSQQDQLRKILRSYSPMFSANP---GRTHWAEHKVDTGTQLPIRSPAYRVAEAVRPEMKSQIDEMLAFGVITPSHSPWASPVVLVPKKDGS-TRFCVDYRRLNDVTTTDAYPMPRVDELLDRLGNAKYLTTLDLSRGYWQIPLAPSAQEKSAFLTPFGLYQFTVMPFGMRNAPATFQRLVNRLLEGMQDFAQAYLDDIAVFSQTWEEHLQHLQRVFAQIQDAGLTLKPEKCHLAMAEVQYLGHRVGGGQLRPDPAKVEAICQWPIPKTQKQVLAFLGTSGYYRKFIPNYSTVAKPLTDLTSRQRSRTIVWTPECESAMNALKQALASSPVLAAPDFSRRFILQTDASNFGLGAVLSQVNTYGEEHPVAYLSRKLLPREAAYATIEKECLAIVWALQKLQPYLYGREFTVVTDHNPLSWLQRVSG-DNGKLLRWSLLLQQYNFTIQHRKGKEHHNADGLSR 753          

Query: 3132 IDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKISR------EKWYG---SKEIPI-------KEELEEQTR-----------------------RKFNVGEEVLVKVETRH-KGQDRYEGPYKVIEKVHDRRYIL 3713
            +D  ++Y    A+ K D  T+   +++ +  R G P EI  D G  F S +++   +   ++   SSPYH QTNG  ER   T++ ++   ++  +K DW   LP + F      Q++TG SP E+++G+++        E W G   S+E+PI       ++ LE+ T                        R+F  G++VL+ V TRH K Q  +EGPY V  K+HD  Y++
Sbjct:    1 MDYATRYPEAVALRKIDAPTVADALIQIFS-RVGFPSEILSDQGPQFTSQLLQCLWQRCGVRAIHSSPYHPQTNGLCERFNGTLKTMLRTFVESGEK-DWERYLPHLLFAYREVPQESTGFSPFELLYGRRVRGPLDLLCEYWEGAPQSQEVPIIPYVLKFRQRLEQMTSLAHDHLSAAQQRQKVWYDRKARERRFMEGDKVLLLVPTRHDKLQAAWEGPYVVTHKLHDTTYVV 232          

Query: 1473 SKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKD--IRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKK-ARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQR-DKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYG--RRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIVEEVRKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKA-----LTITTKEPVKRQDSKEMFEIIFVDI---CGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLIN---ATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGK 3521
            + ++E I    + G IR   SP       V   EKKD  +R C+D+R LN +T +  +P+P I E+ D L G+  FS +DL  AY  + + E  + KTAF+T++G Y +  MPFG+  AP  FQE +  +   +  K  +VYLDDILI+S   E H + + E L  + E  L    EKC     +I FLG+IIS  G + DP+K+ AIQ +  P   K ++ F+G  NYYR+FI  ++ + A +L  +  G   +   W       F+ LK A  +A +L  P+    F ++ DAS    GA+LSQR   DGK    AY S   +S E+ Y I  +ELLAV      ++H L G     T+ TDHK + F+ + K+    Q   W  + S     + YR G  ++ AD +SR+                  +I   +L    E+   +      +       +P       +++ H  +   H G EK  + ++       +   +++ V +C +C  TKA       +    PV  +    +     V++   CG           I  +ID++SK      + K         +  + I R  G P EI  D G  F S   R   K L + L FSS YH QTNG  ER  + +   +    +  QD    DW+++LP  EF  N  +  +TG+SP   V+G+
Sbjct:   16 AAMKEYISENLQRGFIRPSTSPAGAGFFFV---EKKDGGLRPCIDYRGLNKITVKNRYPLPLISELFDQLKGAKIFSKLDLRGAYNLIRIREGDEWKTAFNTRDGHYEYLVMPFGLCNAPAVFQEFVNDIFRDLLGKSVVVYLDDILIFSQDLETHRSQVKEALSRLRENSLFAKLEKCTFEVPKISFLGYIISSRGFEMDPAKVSAIQKWPLPQSTKAIQRFIGFANYYRQFIKGFSSRIAPILSLIRKG--GRPNCWPPVALEAFQSLKDAFISASVLRHPEPHLPFFIEVDASDVGAGAILSQRHSADGKLHPCAYFSKKFSSAEQNYDIGNRELLAVKLALEEWRHLLEGASHPVTIYTDHKNLEFLQSLKRQNPRQ-ARWSLFFSRFHFVLTYRPGTKNRKADALSRSFSPEDRLPIEREPIIPPSRIIASVLPQFAEQILLSQSAAPPDTPIGMAFVPPELRLPILQQTHSSKQAGHPGSEKTLELLQRLVWWPTIRKDVRDFVAACTVCATTKASHSRPCGLLHPLPVPSRPWTHLGMDFIVELPPSCG--------NTVIWVVIDRFSKMAHFVPLRKLPSAVELAQLFIQHIFRLHGFPVEIVSDRGSQFVSRFWRSLCKSLGVSLQFSSAYHPQTNGAAERVNQALEQFLRNHVSLCQD----DWSDLLPWAEFAHNNARHSSTGRSPFLSVYGQ 702          

Query:  930 DCLLDTGARINVMSVNCFNKLRGQQLTKSDDKLRC--------ANESTIETIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGGIELQETFGFRLLKIKDIEASEKDKNYICNIEAKFGRKIKDEERLIRALEQLKINEDS--KLKEIITNSGNVFMADKWDVGRTH--------LVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKD--IRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKK-ARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQR-DKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYG--RRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIVEEVRKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKA-----LTITTKEPVKRQDSKEMFEIIFVDI---CGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLIN---ATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGK-KISREKWYGSKEIPIKEELEEQTRRKFNVGEEVLVKVETRHKG-QDR---YEGPYKVIEKV 3692
               LD+GA  N M +  F K  G  L      +R         + ++   T G+  VQ+   ++ K    I+    +P V+G              +  +       ++     +++ +  +    ++R L+++ ++  S   L  +  +  +VF     +    H        L+   +  RG    + P        + ++E I    + G IR   SP       V   EKKD  +R C+D+R LN +T +  +P+P I E+ D L G+  FS +DL  AY  + + E  + KTAF+T++G Y +  MPFG+  AP  FQE +  +   +  K  +VYLDDILI+S   E H + + E L  + E  L    +KC     +I FLG+IIS  G + DP+K+ AIQ +  P   K ++ F+G  NYYR+FI  ++ + A +L  +  G   +   W       F+ LK A  +A +L  P+    F ++ DAS    GA+LSQR   DGK    AY S   +S E+ Y I  +ELLAV      ++H L G     T+ TDHK + F+ + K+    Q + W  + S     + YR G  ++ AD +SR+                  +I   +L    E+   +      +       +P       +++ H  +   H G EK  + ++       +   +++ V +C +C  TKA       +    PV  +    +     V++   CG           I  +ID++SK      + K         +  + I R  G P EI  D G  F S   R   K L + L FSS YH QTNG  ER  + +   +    +  QD    DW+++LP  EF  N     +TG+SP   V+G+  ++  + +   ++P  ++L       +   +  L K    HK   DR      PYKV EKV
Sbjct:  355 SAFLDSGAAGNFMDL-AFAKKVGISLFPVTPPIRVLAIDDRPLSTDTITLTTGELSVQIGALHLEKMSFLIIPCPSSPVVLG--------------LPWLRLHNPSIDWSSGQISRWSQYCQRHCLILRPLQRVTVSSTSLSALPSVYRDFSDVFCKKSAEFLPPHRRYDCPIDLLPGIMPPRGRTYPLSPAE-----TAAMKEYISENLQRGFIRPSTSPAGAGFFFV---EKKDGGLRPCIDYRGLNKITVKNRYPLPLISELFDQLKGAKIFSKLDLRGAYNLIRIREGDEWKTAFNTRDGHYEYLVMPFGLCNAPAVFQEFVNDIFRDLLGKSVVVYLDDILIFSQDLETHRSQVKEALSRLRENSLFAKLDKCTFEVPKISFLGYIISSRGFEMDPAKVSAIQKWPLPQSTKAIQRFIGFANYYRQFIKGFSSRIAPILSLIRKG--GRPNCWPPVALEAFQSLKDAFISASVLRHPEPHLPFFIEVDASDVGAGAILSQRHSADGKLHPCAYFSKKFSSAEQNYDIGNRELLAVKLALEEWRHLLEGASHPVTIYTDHKNLEFLQSLKRQNPRQVR-WSLFFSRFHFVLTYRPGTKNRKADALSRSFSPEDRLPIEREPIIPPSRIIASVLPQFAEQILLSQSAAPPDTPIGMAFVPPELRLPILQQTHSSKQAGHPGSEKTLELLQRLVWWPTIRKDVRDFVAACTVCATTKASHSRPCGLLHPLPVPSRPWTHLGMDFIVELPPSCG--------NTVIWVVIDRFSKMAHFVPLRKLPSAVELAQLFIQHIFRLHGFPVEIVSDRGSQFVSRFWRSLCKSLGVSLQFSSAYHPQTNGAAERVNQALEQFLRNHVSLCQD----DWSDLLPWAEFAHNNASHSSTGRSPFLSVYGQHPLAFPQDFLLSKVPAADDLAAHMSVIWAATKSNLEKSSLVHKTFADRRRKPSPPYKVGEKV 1282          

Query:  930 DCLLDTGARINVMSVNCFNKLRGQQLTKSDDKLRC--------ANESTIETIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGGIELQETFGFRLLKIKDIEASEKDKNYICNIEAKFGRKIKDEERLIRALEQLKINEDS--KLKEIITNSGNVFMADKWDVGRTH--------LVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKD--IRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKK-ARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQR-DKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYG--RRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIVEEVRKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKA-----LTITTKEPVKRQDSKEMFEIIFVDI---CGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLIN---ATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGK-KISREKWYGSKEIPIKEELEEQTRRKFNVGEEVLVKVETRHKG-QDR---YEGPYKVIEKV 3692
               LD+GA  N M +  F K  G  L      +R         + ++   T G+  VQ+   ++ K    I+    +P V+G   L+       L    I+ S    +       ++ +  +    ++R L+++ ++  S   L  +  +  +VF     +    H        L+   +  RG    + P        + ++E I    + G IR   SP       V   EKKD  +R C+D+R LN +T +  +P+P I E+ D L G+  FS +DL  AY  + + E  + KTAF+T++G Y +  MPFG+  AP  FQE +  +   +  K  +VYLDDILI+S   E H + + E L  + E  L    +KC     +I FLG+IIS  G + DP+K+ AIQ +  P   K ++ F+G  NYYR+FI  ++ + A +L  +  G   +   W       F+ LK A  +A +L  P+    F ++ DAS    GA+LSQR   DGK    AY S   +S E+ Y I  +ELLAV      ++H L G     T+ TDHK + F+ + K+    Q + W  + S     + YR G  ++ AD +SR+                  +I   +L    E+   +      +       +P       +++ H  +   H G EK  + ++       +   +++ V +C +C  TKA       +    PV  +    +     V++   CG           I  +ID++SK      + K         +  + I R  G P EI  D G  F S   R   K L + L FSS YH QTNG  ER  + +   +    +  QD    DW+++LP  EF  N     +TG+SP   V+G+  ++  + +   ++P  ++L       +   +  L K    HK   DR      PYKV EKV
Sbjct:  355 SAFLDSGAAGNFMDL-AFAKKVGISLFPVTPPIRVLAIDDRPLSTDTITLTTGELSVQIGALHLEKMSFLIIPCPSSPVVLGLPWLR-------LHNPSIDWSSGQIS-------RWSQYCQRHCLILRPLQRVTVSSTSLSALPSVYRDFSDVFCKKSAEFLPPHRRYDCPIDLLPGIMPPRGRTYPLSPAE-----TAAMKEYISENLQRGFIRPSTSPAGAGFFFV---EKKDGGLRPCIDYRGLNKITVKNRYPLPLISELFDQLKGAKIFSKLDLRGAYNLIRIREGDEWKTAFNTRDGHYEYLVMPFGLCNAPAVFQEFVNDIFRDLLGKSVVVYLDDILIFSQDLETHRSQVKEALSRLRENSLFAKLDKCTFEVPKISFLGYIISSRGFEMDPAKVSAIQKWPLPQSTKAIQRFIGFANYYRQFIKGFSSRIAPILSLIRKG--GRPNCWPPVALEAFQSLKDAFISASVLRHPEPHLPFFIEVDASDVGAGAILSQRHSADGKLHPCAYFSKKFSSAEQNYDIGNRELLAVKLALEEWRHLLEGASHPVTIYTDHKNLEFLQSLKRQNPRQAR-WSLFFSRFHFVLTYRPGTKNRKADALSRSFSPEDRLPIEREPIIPPSRIIASVLPQFAEQILLSQSAAPPDTPIGMAFVPPELRLPILQQTHSSKQAGHPGSEKTLELLQRLVWWPTIRKDVRDFVAACTVCATTKASHSRPCGLLHPLPVPSRPWTHLGMDFIVELPPSCG--------NTVIWVVIDRFSKMAHFVPLRKLPSAVELAQLFIQHIFRLHGFPVEIVSDRGSQFVSRFWRSLCKSLGVSLQFSSAYHPQTNGAAERVNQALEQFLRNHVSLCQD----DWSDLLPWAEFAHNNASHSSTGRSPFLSVYGQHPLAFPQDFLLSKVPAADDLAAHMSVIWAATKSNLEKSSLVHKTFADRRRKPSPPYKVGEKV 1282          

Query:  900 ITVRMNGENF--DCLLDTGARINVMSVNCFNKLRGQQLTKSDDKLRC--------ANESTIETIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGGIELQETFGFRLLKIKDIEASEKDKNYICNIEAKFGRKIKDEERLIRALEQLKINEDS--KLKEIITNSGNVFMADKWDVGRTH--------LVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKD--IRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKK-ARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQR-DKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYG--RRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIVEEVRKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKA-----LTITTKEPVKRQDSKEMFEIIFVDI---CGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLIN---ATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGK-KISREKWYGSKEIPIKEELEEQTRRKFNVGEEVLVKVETRHKG-QDR---YEGPYKVIEKV 3692
            + +R++ +       LD+GA  N M +  F K  G  L      +R         + ++   T G+  VQ+   ++ K    I+    +P V+G   L+       L    I+ S    +       ++ +  +    + + L+++ ++  S   L  +  +  +VF     +    H        L+   +  RG    + P        + ++E I    + G IR   SP       V   EKKD  +R C+D+R LN +T +  +P+P I E+ D L G+  FS +DL  AY  + + E  + KTAF+T++G Y +  MPFG+  AP  FQE +  +   +  K  +VYLDDILI+S   E H + + E L  + E  L    EKC     +I FLG+IIS  G + DP+K+ AIQ +  P   K ++ F+G  NYYR+FI D++ + A +L  +  G   +   W       F+ LK A  +A +L  P+    F ++ DAS    GA+LSQR   DGK    AY S   +S E+ Y I  +ELLAV      ++H L G     T+ TDHK + F+ + K+    Q + W  + S  +  + YR G  ++ AD +SR+                  +I   +L    E+   +      +       +P       +++ H  +   H G EK  + ++       +   +++ V +C +C  TKA       +    P+  +    +     V++   CG           I  +ID++SK      + K         +  + I R  G P EI  D G  F S   R   K L + L FSS YH QTNG  ER  + +   +    +  QD    DW+++LP  EF  N     +TG+SP   V+G+  ++  +     E+P  ++L       +   +  L K    HK   DR      PYKV EKV
Sbjct:  343 VQIRLSSQAIPVSAFLDSGAAGNFMDL-AFAKKVGISLFPVTPSIRVFAIDDRPLSTDTITLTTGELSVQIGALHLEKMSFLIIPCPSSPVVLGLPWLR-------LHNPSIDWSSGQIS-------RWSQYCQRHCLIPQPLQRVTVSSTSFSALPSVYRDFSDVFCKKSAEFLPPHRRYDCPIDLLPGTMPPRGRTYPLSPAE-----TAAMKEYISENLQRGFIRPSTSPAGAGFFFV---EKKDGGLRPCIDYRGLNKITVKNRYPLPLISELFDQLKGAKIFSKLDLRGAYNLIRIREGDEWKTAFNTRDGHYEYLVMPFGLCNAPAVFQEFVNDIFRDLLGKSVVVYLDDILIFSQDLETHRSQVKEALSRLRENFLFAKLEKCTFEVPKISFLGYIISSRGFEMDPAKVSAIQKWPLPQSTKAIQRFIGFANYYRQFIKDFSSRIAPILSLIRKG--GRPNCWPPVALEAFQSLKDAFISASVLRHPEPHLPFFIEVDASDVGAGAILSQRHSADGKLHPCAYFSKKFSSAEQNYDIGNRELLAVKLALEEWRHLLEGASHPVTIYTDHKNLEFLQSLKRQNPRQAR-WSLFFSRFNFVLTYRPGTKNRKADALSRSFSPEDRLPIEQEPIIPPFRIIASVLPQFAEQILLSQSAAPSDTPIGMAFVPPELRLPILQQTHSSKQAGHPGSEKTLELLRRLVWWPTIRKDVRDFVAACTVCATTKASHSRPCGLLHPLPIPSRPWTHLGMDFIVELPPSCG--------NTVIWVVIDRFSKMAHFIPLRKLPSAVELAHLFIQHIFRLHGFPVEIVSDRGSQFVSRFWRSLCKSLGVSLQFSSAYHPQTNGAAERVNQALEQFLRNHVSLCQD----DWSDLLPWAEFAHNNASHSSTGRSPFLSVYGQHPLAFPQDLLLSEVPAADDLAAHMSVIWAATKSNLEKSSLVHKTFADRRRKPSPPYKVGEKV 1282          

Query: 4444 KKRIKDMSHDIEEIVNYKLSKKYF---ALQIDESVDISSKAQLLALVRFIDENEIVNQFLCCRELTEHTTGKDIFNCITTYLEKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKEKNPNIISTHCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFPSI----------QTNNVTDIIPAIIEHLTILDEIIACYFSSLKLESYDWIRNPFGTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSNEHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTLTNIKTKKRERLTDLEEEMRVAISYIRPNIGEICKTRQAQISH 5766
            ++RI DMS DI + V  ++        ++Q+DES D+++  QL+  VR+I++ +  ++FLCC+ L    T  D+F  + ++L + +ISW    G+CTDG P+  GC  G   LV  ++P  I  HC LHL+ L  KTLP   +  +  V+  VN++K+  L +R+F QL   +D   ++LLLHTE R LSRGKVL R+ EL+DEL  +F   A+ +F   F ++    K+AYL DIF  LN +N S+QG N   L  ++KI +F  K+  W+ ++ +N    M P++          Q   +T +I ++ EHL +L   I+ YF +L    +   R+PF     +       +E+   L+ + + + +F+ M    FW+   + +P LS+  + + L F T+YLCE GFS+L  IK+K R RL  +E+++R A++   P I ++ + +Q+Q SH
Sbjct:  308 RRRIHDMSADILDQVVQEIKSAPLPICSIQLDESTDVANCLQLMVYVRYINDGDFKDEFLCCKPLERTATALDVFEAVDSFLRQHEISWKSICGVCTDGAPATLGCQSGFQRLVLNESPKAIGAHCMLHLQTLAMKTLPQDFQEVMKSVLSSVNFVKASSLNSRLFLQLCSDLDEPSKTLLLHTEGRWLSRGKVLKRIFELRDELKMFFNQKAIRQFEALFSDNSALQKVAYLVDIFTILNELNLSLQGPNSTCLDLSEKIHSFQMKLQLWQKKLDENK-FYMLPTLSAFFEEHDIEQHKRITVVI-SVKEHLDMLASEISWYFPNLPEIPFALARSPFSV--KAEDVPETAQEDFTRLTNSDAARADFSTMPVTQFWVKCLQSYPVLSEMVLRLLLPFPTTYLCETGFSSLLVIKSKYRSRLV-VEDDLRCALAKTTPRISDLVRKKQSQPSH 756          

Query: 4034 RQYSDEYISFGFAWTDEKECPIPKCVVCGVELSNSAMFPAKLNRHFTNSHANLVSKNNDYFKRLLGMQAKQFKGAMTISDKAQIASYKEL*LIALK----LKPHTIAESLILP 4360
            R+Y++ ++ +GF  T       P+CV+CGV LS  +M P KL RHF + H++   K+ +YF+       K      + S+K  +A+ +   L+AL+    +KPHT AE L+ P
Sbjct:  167 RKYNEGFLQYGFTSTITVGIERPQCVICGVVLSAESMKPNKLKRHFESKHSSFAGKDTNYFRSKADGLKKARPDTGSKSNKQNVAAVETSYLVALRIARDMKPHTFAEHLLFP 279          

Query: 4450 RIKDMSHDIEEIVNYKLSK-KYFALQIDESVDISSKAQLLALVRFID--ENEIVNQFLCCRELTEHTTGKDIFNCITTYLEKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKEKNPNIIS-THCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFP---------SIQTNNVTDIIPAIIEHLTILDEII-ACYFSSLKLESYD-WIRNPFGTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSNEHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTLTNIKTKKRERLTDLEEEMRVAISYIRPNIGEICKTRQ 5751
            RIK +S DIE+ +  K+ + ++FALQ+DES + +    LL  VRFID    ++  + L C E+   +T  ++F  I  Y++   ++W+ CVG CTDG  SM        + ++E   N ++ THCF+H E L +K L   L   L +  QI++++K+    +++   L   M +++ +L L+ E+R LSRG++L RL EL+ E+   F N   +   + F ++ W AKLAYLADIF  +N +N+S+QG         +K+  F K++  W  R  +N+   MFP          +   N+  I   I EHL  L +I  ACY     L S + W+ +PF T+  SN     +EE++  LS +   +     MS   FW+  +  +P L +KA+ + L FS++ LC+  FS LT     K+  L      +R+A++ + P I ++ K ++
Sbjct:  718 RIKKLSDDIEDQLLQKVRESRWFALQVDESSEATEVPLLLCYVRFIDYDRGDVKEELLFCTEMPSPSTDLEVFELINKYIDSRSLNWNHCVGFCTDGAASMTDRYFRLRSKIQEIAKNTVTFTHCFIHREHLAAKKLSPCLHEILLQSSQILSFVKNSASDSQMLTILCEEMGSEHVNLPLNAEVRWLSRGRILTRLFELRHEIEI-FLNQKHSDLARYFHDEEWIAKLAYLADIFSLINKLNSSLQGTMTTFFNLYNKVDVFQKRLKMWLKRAQEND-YGMFPLFSEFLDSSDVSVKNIASI---IFEHLEGLSQIFHACYPPEEDLRSGNLWLTDPFATYH-SNNLTDSEEEKLAVLSADTGFQSVHKSMSVTQFWVNAKTSYPKLHEKALKLLLPFSSTCLCDATFSALT---ASKQRDLRTCGPTLRLAVTSLVPRIEKLAKEKE 1157          

Query: 4031 NRQYSDEYISFGF--AWTDEKECPIPKCVVCGVELSNSAMFPAKLNRHFTNSHANLVSKNNDYF-KRLLGM--QAKQFKGAMTISDKAQIASYKEL*LIALKLKPHTIAESLILPSCCEI 4375
            ++ Y+ EYI FGF      E+  P P+CV+CG  L + ++ P  L+ H    H++L +K  D+F ++ L M  Q    K  + + +    ASY     IA + KP +IAE LI P   E+
Sbjct:  573 SQTYNAEYIRFGFIICSGSEESSPSPQCVICGEVLPSESVMPVSLSNHLKAKHSDLENKPVDFFEEKSLEMECQNSSLKKCLLVEESLVKASYLIAFQIAARNKPFSIAEELIKPYLVEM 692          

Query: 4450 RIKDMSHDIEEIVNYKLSK-KYFALQIDESVDISSKAQLLALVRFID--ENEIVNQFLCCRELTEHTTGKDIFNCITTYLEKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKEKNPNIIS-THCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFP---------SIQTNNVTDIIPAIIEHLTILDEII-ACYFSSLKLESYD-WIRNPFGTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSNEHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTLTNIKTKKRERLTDLEEEMRVAISYIRPNIGEICKTRQ 5751
            RIK +S DIE+ +  K+ + ++FALQ+DES + +    LL  VRFID    ++  + L C E+   +T  ++F  I  Y++   ++W+ CVG CTDG  SM        + ++E   N ++ THCF+H E L +K L   L   L +  QI++++K+    +++   L   M +++ +L L+ E+R LSRG++L RL EL+ E+  +  N   +   + F ++ W AKLAYLADIF  +N +N+S+QG         +K+  F K++  W  R  +N+   MFP          +   N+  I   I EHL  L +I  ACY     L S + W+ +PF T+  SN     +EE++  LS +   +     MS   FW+  +  +P L +KA+ + L FS++ LC+  FS LT     K+  L      +R+A++ + P I ++ K ++
Sbjct:  810 RIKKLSDDIEDQLLQKVRESRWFALQVDESSEATEVPLLLCYVRFIDYDRGDVKEELLFCTEMPSPSTDLEVFELINKYIDSRSLNWNHCVGFCTDGAASMTDRYFRLRSKIQEIAKNTVTFTHCFIHREHLAAKKLSPCLHEILLQSSQILSFVKNSASDSQMLTILCEEMGSEHVNLPLNAEVRWLSRGRILTRLFELRHEIEIFL-NQKHSDLARYFHDEEWIAKLAYLADIFSLINKLNSSLQGTMTTFFNLYNKVDVFQKRLKMWLKRAQEND-YGMFPLFSEFLDSSDVSVKNIASI---IFEHLEGLSQIFHACYPPEEDLRSGNLWLTDPFATYH-SNNLTDSEEEKLAVLSADTGFQSVHKSMSVTQFWVNAKTSYPKLHEKALKLLLPFSSTCLCDATFSALT---ASKQRDLRTCGPTLRLAVTSLVPRIEKLAKEKE 1249          

Query: 4031 NRQYSDEYISFGF--AWTDEKECPIPKCVVCGVELSNSAMFPAKLNRHFTNSHANLVSKNNDYF-KRLLGM--QAKQFKGAMTISDKAQIASYKEL*LIALKLKPHTIAESLILPSCCEI 4375
            ++ Y+ EYI FGF      E+  P P+CV+CG  L + ++ P  L+ H    H++L +K  D+F ++ L M  Q    K  + + +    ASY     IA + KP +IAE LI P   E+
Sbjct:  665 SQTYNAEYIRFGFIICSGSEESSPSPQCVICGEVLPSESVMPVSLSNHLKAKHSDLENKPVDFFEEKSLEMECQNSSLKKCLLVEESLVKASYLIAFQIAARNKPFSIAEELIKPYLVEM 784          

Query: 4513 FALQIDESVDISSKAQLLALVRFIDEN-EIVNQFLCCRELTEHTTGKDIFNCITTYLEKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKE------KNPNIISTHCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFPSIQT-----NNVTDIIPAII----EHLTILDEIIACYFSSLKLESYDWIRNPFGTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSNEHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTL 5640
            +++ IDE  DI+   QL   +R +D+N ++  + L    +T   +G +IF  +   L+K  I W   V + + G P+M     G VT ++       K  ++ S  C +H E L ++ L   +   +D VV  VN+I SR L    F  L   +D++Y SLL HT ++ L RG VL R  E  +E+  +    +  K V    +  W   LA+L D+  +LN+++ S+QG ++ +    D I AF  K+  W+  + +NN L  FP++++     ++  + IP I+    E    L +  +C  S L L S     +PF T    +      + E+I L  N  L+ ++ K+    F+  +   +P        +   FS++++CE  FS L
Sbjct:  541 YSIAIDEITDINDTTQLAIFIRGVDDNFDVSEELLDTVPMTGAKSGNEIFLRVEKSLKKFSIDWSKLVSVASTGTPAMMDANSGLVTKLRARAASCCKGADLKSVRCIIHPEWLCAQKL--RMGHVMDVVVDSVNWICSRGLNHGDFTTLLYELDSQYGSLLYHTALKWLGRGLVLRRFFESLEEIDSFMS--SRGKPVPQLSSRDWILDLAFLVDMTTHLNTLDASLQGHSQIVTQMYDFIRAFLAKLCLWETHLARNN-LAHFPTLKSVSRSESDGLNYIPKIVELKAEFQRRLSDFKSCE-SELTLFS-----SPFST--TIDSVREELQMEVIDLQCNTVLRTKYDKVGVPDFYKHLWSSYPKYRSHCARMLSMFSSTHICEQLFSIL 919          

Query: 1614 NAVTERQAFPMPNIDEMLDLLGGSVFFSSIDL-----GNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKGAMV--YLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAK-KARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKD-GKERVIAYGSHSMTSHEKGYCITRKELLAV 2477
            + +T+RQ +    + E+ D L G+ +F+ ++L         + V   E++   +     +   C+   PF + +       ++  +L  I G  V  +  ++L+YS S+E+H   + +VL       +  + +K Q  ++    LG  IS +GV+ + + +  I     P   + L+S + +   YR F+ ++A   A ++ QL    S++   W E      E LK A   +P+L  P  +  F L+TD +   + A L Q D + GK+   A+ S  +++ E  Y      +L +
Sbjct:  898 DMLTDRQDYTQ-MVPELFDQLHGAAWFTKLELLGIKESEMRHTVTHTEDTWRASFGFGLHQMRCYR--PFTMNSYSDEGNNIVHFILKDILGLFVICHGREVLVYSMSQEEHSQHVRQVLVRFRYHNIYCSLDKTQFHRQTAEILGFNISPKGVKLNKNLMNLIVGCPVPGSRRCLQSVIDLVYPYRHFVENFAVIAAPLVRQLL---SSEPYYWGEEEQEALESLKRAFRKSPVLYHPKPQNPFYLETDITGSFLSASLVQTDDETGKKSTCAFYSRPLSTMEVEYPRVEMRILPI 1188          

Query: 1326 KLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGK-ERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRT---------------------KCDTCVQCQMAH-EEAKKGKIKTRLLDSIR---------EEGRSNIQHGIVEEV---RKKTMIPENELQETIKEIHRLLC---HAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTK---EPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFG-------------------KKISREKWYGSKEIPIKEELEE---------QTRRK---FNVGEEVLVKVETRHKG------QDRYEGPYKVIEKVHDRRYILRNEDGKRIER--NVEKLKNFLRR 3776
            K +EII N      AD  ++   H ++ K   R     ++PY      E +I + +Q L +N  I    SP ++P++ V KK+    RLC+D+R LN  T    FP+P ID +L  +G +  F+++DL + Y+Q+ +E + + KTAF T +G+Y +  MPFG+  AP TF   M      ++   VYLDDILI+S S E+H+  L  VL+ ++   L +  +KC+   EE  FLG+ I  + +     K  AI++F  P  VK+ + FLG+ NYYRRFI + +K A+ ++         K +W+E  +   + LK AL  +P+L   + K  + L TDAS D IGAVL + D   K   V+ Y S S+ S +K Y     ELL +     HF++ L+G+ FTLRTDH ++  +    +P   + Q W++ L++ D  +EY  G  +  AD +SR                      K D      + H +E  +  +    + + R         E  R N  + + +E+   + + ++P  +    ++  H       H GV      +   Y    L   I + +R+C  CQ  K+         +P+   + + +   I +D    L  T      IL ++D++SK     A  K  + T    +L ++I  + G P+ I  D      +   +E TK L IK   SS  H QT+GQ ER  +T+  L+ A      + +W   LP++EF  N+T  +T GKSP EI  G                     +   K   +  I  KE+LE            RRK    N+G+ VLV  +   K       Q  Y GP++V++K++D  Y L     K+  R  NV+ LK F+ R
Sbjct:  563 KYREIIRNDLPPRPADINNIPVKHDIEIKPGARLP--RLQPYHVTEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPKKDGT-FRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAPLQHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPIQLFICD----KSQWTEKQDKAIDKLKDALCNSPVLVPFNNKANYRLTTDASKDGIGAVLEEVDNKNKLVGVVGYFSKSLESAQKNYPAGELELLGIIKALHHFRYMLHGKHFTLRTDHISLLSLQNKNEP-ARRVQRWLDDLATYDFTLEYLAGPKNVVADAISRAVYTITPETSRPIDTESWKSYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKN--YSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWL--DISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYASTNIQ-NWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKKFVYR 1447          

Query: 1326 KLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGK-ERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRT---------------------KCDTCVQCQMAH-EEAKKGKIKTRLLDSIR---------EEGRSNIQHGIVEEV---RKKTMIPENELQETIKEIHRLLC---HAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTK---EPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRF-GCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFG-------------------KKISREKWYGSKEIPIKEELEE---------QTRRK---FNVGEEVLVKVETRHKG------QDRYEGPYKVIEKVHDRRYILRNEDGKRIER--NVEKLKNF 3767
            K +EII N      AD  ++   H ++ K   R     ++PY      E +I + +Q L +N  I    SP ++P++ V KK+    RLC+D+R LN  T    FP+P ID +L  +G +  F+++DL + Y+Q+ +E + + KTAF T +G+Y +  MPFG+  AP TF   M      ++   VYLDDILI+S S E+H+  L  VL+ ++   L +  +KC+   EE  FLG+ I  + +     K  AI++F  P  VK+ + FLG+ NYYRRFI + +K A+ ++         K +W+E  +   E LK AL  +P+L   + K  + L TDAS D IGAVL + D   K   V+ Y S S+ S +K Y     ELL +     HF++ L+G+ FTLRTDH ++  +    +P   + Q W++ L++ D  +EY  G  +  AD +SR                      K D      + H +E  +  +    + + R         E  R N  + + +E+   + + ++P  +    ++  H       H GV      +   Y    L   I + +R+C  CQ  K+         +P+   + + +   I +D    L  T      IL ++D++SK     A  K  + T    +L ++I  + G P+ I  D      +   +E TK L IK   SS  H QT+GQ ER  +T+  L+ A +    + +W   LP++EF  N+T  +T GKSP EI  G                     +   K   +  I  KE+LE            RRK    N+G+ VLV  +   K       Q  Y GP++V++K++D  Y L     K+  R  NV+ LK+ 
Sbjct:  589 KYREIIRNDLPPRPADINNIPVKHDIEIKPGARLP--RLQPYHVTEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPKKDGT-FRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAPLQHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPIQLFICD----KSQWTEKQDKAIEKLKAALCNSPVLVPFNNKANYRLTTDASKDGIGAVLEEVDNKNKLVGVVGYFSKSLESAQKNYPAGELELLGIIKALHHFRYMLHGKHFTLRTDHISLLSLQNKNEP-ARRVQRWLDDLATYDFTLEYLAGPKNVVADAISRAIYTITPETSRPIDTESWKSYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKN--YSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWL--DISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYVSTNIQ-NWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKSL 1470          

Query:  888 GRPS-ITVRMNGENFDCLLDTGARINVMSVNCFNKL--RGQQLTKSDDKLRCANESTI---ETIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGGIELQET----FGFRLLKIKDIEASEKDK----NYICNIEAKFGRKIKD--EERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKE----KKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCV---QCQMAHEE 2729
            G+P  IT++    N  CL+DTG+ +N+ S N F+           + +     N+S I   + +  T  +  +   S+    ++  K+  +    I  ++     +  +   I+ I   E+      N I +   +   KI    E  L R LE L   E  +L  ++    ++   +   +  T+  KH I T+        Y  P   E ++E  IQ++   GIIR  NSP+N+P+  V KK+    K+  R+ +D+R+LN +T     P+PN+DE+L  LG   +F++IDL   ++Q+E++ ES  KTAFSTK+G Y + RMPFG+  AP TFQ  M  +L  +  K  +VYLDDI+++S+S ++H   LG V + + +A L++  +KC+ +K+E  FLGH+++ +G++ +P KI+AIQ +  P   K++++FLG+  YYR+FI ++A  A+ + + C   + K    +   +S F+ LK  ++  PIL  PD  K+F L TDAS   +GAVLSQ   DG    ++Y S ++  HE  Y    KELLA+ +    F+HYL GR F + +DH+ ++++   K P  S+   W   LS  D  ++Y KG  +  AD +SR K +      Q Q + EE
Sbjct:   11 GKPQYITIKYKENNLKCLIDTGSTVNMTSKNIFDLPIQNTSTFIHTSNGPLIVNKSIIIPSKILFPTTNEFLLHPFSENYDLLLGRKLLAEAKATISYRDQEVTLYNNKYKLIEGIATHEQSHFQNVNMIPDTMLRQPNKISPILESDLYR-LEHLNNEEKQRLCALLQKYHDIQYHEGDKLTFTNQTKHTINTKHNLPLYSKYSYPQAYEQEVESQIQDMLNQGIIRTSNSPYNSPIWVVPKKQDASGKQKFRIVIDYRKLNEITVGDRHPIPNMDEILGKLGRCNYFTTIDLAKGFHQIEMDPESVSKTAFSTKHGHYEYLRMPFGLKNAPATFQRCMNDILRPLLNKHCLVYLDDIIVFSTSLDEHLQSLGLVFEKLAKANLKLQLDKCEFLKQETTFLGHVLTPDGIKPNPEKIEAIQKYPIPTKPKEIKAFLGLTGYYRKFIPNFADIAKPMTK-CLKKNMKIDTTNPEYDSAFKKLKYLISEDPILKVPDFTKKFTLTTDASDVALGAVLSQ---DG--HPLSYISRTLNEHEINYSTIEKELLAIVWATKTFRHYLLGRHFEISSDHQPLSWLYRMKDP-NSKLTRWRVKLSEFDFDIKYIKGKENCVADALSRIKLEETYLSEQTQHSAEE 641          

Query: 2847 ELQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMF-EIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINAT-LQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKISREKWYGSKEIPIKEELEEQTRRKFNVGEEVLVKVETRHKG----QDRYEGPYKVIEKV 3692
            E +E I   H  L H G++K      + Y   +    IQ I+  C IC   K     T  P K     E   E   +DI           K+ +  ID YSK+  L  I  +D    K  ++ +   + G PK ++ D   AF S  ++ + +  E++L  ++         IER  +TI + I      D ++T  +++   +    + TK  TTG++PA I           Y  + I   ++ +E    K N  + V  +V+TR++     + + E P+K  + V
Sbjct:  749 EFKELILTAHEKLLHPGIQKTTKLFGETYYFPNSQLLIQNIINECSICNLAKTEHRNTDMPTKTTPKPEHCREKFMIDIYS------SEGKHYVSCIDIYSKFATLEEIKTKDWIECKNALM-RIFNQLGKPKLLKADRDGAFSSLALKRWLESEEVELQLNTT--KTGVADIERLHKTINEKIRIIKTSDDEETKLSKMETVLNIYNHKTKHDTTGQTPAHIFL---------YAGQPILDTQQNKENKINKIN-NDRVEYEVDTRYRKGPLQKGKLENPFKPTKNV 1017          

Query: 4447 KRIKDMSHDIEEIVNYKLSK-KYFALQIDESVDISSKAQLLALVRFIDENEIVNQFLCCRELTEHTTGKDIFNCITTYLEKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKEKNPNIISTHCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFPSI-----QTNNVTD--IIPAIIEHLTILDEIIACYFSSLKLESYDWIRNPFGTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSNEHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTLTNIKTKKRERLTDLEEEMRVAISYIRPNIGEIC-KTRQAQISH 5766
            +RIKD++ DIEE +  +L     F+LQ+DES D+S  A LL  VR+     I    L C  L  + TG++IFNCI ++++K +I W+ CV +C+D   +M G I   VTL+K   P   S+HC L+   L  KT+P +LK+ LD+ VQI+NYIK+RP Q+R+ K L   M A++ +LLL+TE+R LSRGKVL RL EL+ ELL +  +    +      N  W  +LAYLADIF  LN VN S+QGKN  + T  DK+ +  +K+ +W + + + N  D FP++     + N+  D  I  AI++HL  L   +  YF  +  + + W+RNPF         ++   E +I L+++  +K  F+++S   FW  + +E+PS++++A+ + L F+T +LCE GFS     KTK R+RL D    MR+ +S I PNI  IC K  Q   SH
Sbjct:  251 RRIKDLAADIEEELVCRLKICDGFSLQLDESADVSGLAVLLVFVRYRFNKSIEEDLLLCESLQSNATGEEIFNCINSFMQKHEIEWEKCVDVCSDASRAMDGKIAEAVTLIKYVAPESTSSHCLLYRHALAVKTMPTSLKNVLDQAVQIINYIKARPHQSRLLKILCEEMGAQHTALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAF--RLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEEN-FDCFPTLSDFLTEINSTVDKNICSAIVQHLRGLRSTLLKYF-PVTNDIHAWVRNPFTVTVKPASLVARDYESLIDLTSDSQVKQSFSELSLNDFWSSLIQEYPSVARRAVRVLLPFATMHLCETGFSYYAATKTKYRKRL-DAAPHMRIRLSNITPNIKRICDKKTQKHCSH 694          

Query: 4034 RQYSDEYISFGFAWTDEKECPIPKCVVCGVELSNSAMFPAKLNRHFTNSHANLVSKNNDYFKRLLGM----QAKQFKGAMTISDKAQIASYKEL*LIALKLKPHTIAESLILPSCCEIV 4378
            R+Y + Y+SFGF +   ++ P  +CV+C   LSNS++ P+KL RH    HA    K+  +FK+ L      +    K   T ++ A  ASY     IAL  + HTI E LI P   ++V
Sbjct:  109 RKYDESYLSFGFTYFGNRDAPHAQCVLCKKILSNSSLAPSKLRRHLETKHAAYKDKDISFFKQHLDSPENNKPPTPKIVNTDNESATEASYNVSYHIALSGEAHTIGELLIKPCAKDVV 227          

Query: 4447 KRIKDMSHDIEEIVNYKLSK-KYFALQIDESVDISSKAQLLALVRFIDENEIVNQFLCCRELTEHTTGKDIFNCITTYLEKSQISWDFCVGICTDGCPSMAGCIKGCVTLVKEKNPNIISTHCFLHLEVLVSKTLPNTLKSALDKVVQIVNYIKSRPLQARIFKQLRISMDAKYESLLLHTEIRSLSRGKVXXXXXXXXXXXXXYFQNVAMNKFVKNFENDIWCAKLAYLADIFKYLNSVNTSIQGKNENILTSTDKILAFNKKILYWKNRITKNNTLDMFPS-------IQTNNVTDIIPAIIEHLTILDEIIACYFSSLKLESYDWIRNPFGTFEFSNXXXXXXXXXXXXXXTNRSLKMEFTKMSNEHFWIFVQEEHPSLSKKAITI*LQFSTSYLCELGFSTLTNIKTKKRERLTDLEEEMRVAISYIRPNIGEIC-KTRQAQISH 5766
            +RIKD++ DIEE +  +L     F+LQ+DES D+S  A LL  VR+     I    L C  L  + TG++IFNCI ++++K +I W+ CV +C+D   +M G I   VTL+K   P   S+HC L+   L  K +P +LK+ LD+ VQI+NYIK+RP Q+R+ K L   M A++ +LLL+TE+R LSRGKVL RL EL+ ELL +  +    +      N  W  +LAYLADIF  LN VN S+QGKN  + T  DK+ +  +K+ +W + + + N  D FP+       I +    DI  AI++HL  L   +  YF  +  ++  W+RNPF         ++   E +I L+++  +K  F+++S   FW  + +E+PS++++A+ + L F+T +LCE GFS     KTK R+RL D    MR+ +S I PNI  IC K  Q   SH
Sbjct:  251 RRIKDLAADIEEELVCRLKICDGFSLQLDESADVSGLAVLLVFVRYRFNKSIEEDLLLCESLQSNATGEEIFNCINSFMQKHEIEWEKCVDVCSDASRAMDGKIAEAVTLIKYVAPESTSSHCLLYRHALAVKIMPTSLKNVLDQAVQIINYIKARPHQSRLLKILCEEMGAQHTALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAF--RLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEEN-FDCFPTLSDFLTEINSTVDKDICSAIVQHLRGLRSTLLKYF-PVTNDNNTWVRNPFTVTVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYRKRL-DAAPHMRIRLSNITPNIKRICDKKTQKHCSH 694          

Query: 4034 RQYSDEYISFGFAWTDEKECPIPKCVVCGVELSNSAMFPAKLNRHFTNSHANLVSKNNDYFKRLLGM----QAKQFKGAMTISDKAQIASYKEL*LIALKLKPHTIAESLILPSCCEIV 4378
            R+Y + Y+SFGF +   ++ P  +CV+C   LSNS++ P+KL RH    HA    K+  +FK+ L      +    K   T ++ A  ASY     IAL  + HTI E LI P   ++V
Sbjct:  109 RKYDESYLSFGFTYFGNRDAPHAQCVLCKKILSNSSLAPSKLRRHLETKHAAYKDKDISFFKQHLDSPENNKPPTPKIVNTDNESATEASYNVSYHIALSGEAHTIGELLIKPCAKDVV 227          

Query:  894 PSITVRMNGENFDCLLDTGARINVMSVNCFNKLRGQQLTKSDDKLRCANESTIETIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGG----IELQETFGFRLLKIK----DIEASEKDKNYICNIEAKFGRKIKDEE-------RLIRA--LEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVT-RGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLK---KEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTK------CDTCVQCQMA-----HEEAKKGKIKTRLLD------SIREEG-RSNIQH--GIVEEVR-------------------------KKTMIPENELQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKI 3527
            P +  ++ G +F+CLLD+G+  +++    +   +   +     ++   N   +  +   +  V IG  +  + F V  K+   V+ G    I +Q       L ++            K     +E + G+ +   E       +  R+  +  L  +   +++++I     +F  +    GRTH V+H+I T    PI     R P++L+ ++E+ + ++ E GIIR   SPW +P++ V KK+   +RLC+D+RQLNAVT++ +FP+P ID+ +D L G+ +FS++DL + Y+QVE+E   + KTAF   +G Y F  MPFG+  AP TFQ +M +VLG +  K  +VYLDD++++  + ++H   L  VL  + EAGL++NP KC  ++ E+++LGH+IS+ GV  DP K++ ++ +  P  V+++RSFLG+ +YYRRF+  ++  A+ L  L      +  EWSE     F+ LK AL TAPIL  PD +   K FILDTDAS   IGAVLSQ D + KE VIAYG+ ++   E+ YC TRKE+LA+ +F  HF+HYL GRRF +RTDH ++ ++   K P   Q   W  +L   +   ++R G+ H+NAD +SR        C +C +  MA      E  +   I++   D       I+E G R   Q   G   E R                          + ++PE+ ++  ++E+H  L HAG  K+ +  K R+   H    ++++  SC +C + K        P++   +    EI+ VDI GPL ET    +YIL ++D ++K+     + + D  T  K I + WI R+G P ++  D G  FES MM E  ++L I+   ++ YH Q NG +ER  RT++ L+ A +       W E + +      A+   +T +SP  ++ G+++
Sbjct:  285 PVLKAKVGGRDFECLLDSGSVCSLLDKETYTICQFDAIAGPGSQVLAVNGQPLHILACVRGTVQIGKWTCTLNFFVVPKLPFHVVLGSNYLITMQCILDLPNLAVQVYGERFPLEPVYKTLAGVVEVRTGQHVTKGEVHAEFEWQKFRSTIISHLPAHLAQRVRDVIEKHRAIFWWEGQPPGRTHFVRHRIDTGEAHPIRQAARRLPVHLQGQVEQLLTDMLEKGIIRPSTSPWASPVVLV-KKKDGSLRLCVDYRQLNAVTKKDSFPLPRIDDTIDALSGTEWFSTLDLASGYWQVEVEPSDRLKTAFVVPSGLYEFETMPFGLTNAPATFQRLMQQVLGDLIPKQCLVYLDDVIVHGRTVDEHLHNLSNVLSRLAEAGLKLNPAKCSFMRTEVKYLGHVISQSGVSCDPEKVRKVKEWPTPESVEEIRSFLGLASYYRRFVPRFSHIAKPLTLLTE--KGRVFEWSEDCQQSFDRLKDALCTAPILALPDTRADAKMFILDTDASDVAIGAVLSQLDNNDKEHVIAYGNRNLNRSERNYCTTRKEMLALVHFIKHFRHYLLGRRFLVRTDHSSLQWLQNFKDP-EGQVARWQEFLQEYNFECKHRPGLRHRNADALSRRPIRDHGDCPSCTRYSMAITIRPEENNRWAAIQSSDADLQIIYRRIKEGGPRPTTQEMAGSSWEARCLWSLWNHLYIADNVLYYQYGPTYESQIVVPESAVRSVLQELHENLGHAGQNKLEEAAKRRFWWPHQRRDVKDVCSSCGLCAQIKNPKRQQCAPLQSMLTGYPNEIVEVDIVGPLPETTRGNRYILVMVDHFTKWCEAVPVPRADGGTTAKFIFDHWISRWGAPTQLHTDRGSNFESTMMHELCRILGIRKTRTTAYHPQGNGAVERVNRTLKSLLKAFVSSENTRSWDEAVSQCLLAYRASVHSSTAQSPHYLLTGREM 1226          

Query: 1278 ERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVT-RGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKGA--MVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTC----------VQCQMAHEEAKKGKIKTRLLDS---------------------------------IREEGRSNI-QHGIV---------EEVRKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKI-------------------------SREKWYGSKEIPIKEELEEQTRR------------KFNVGEEVLVKVETRHKGQDRYEGPYKVIEKVHDRRYILRNEDGKR--IERNVEKLKNFLRRGI 3782
            E+++ + ++      S L  I+    +V      D+GRT LV+H I T   +P+   P R P +  +++E  +  +    ++   +SPW +P++ V KK+    R C+D+RQLN +T + A P+P ID+ LD L G+ +FS++DL + Y+QVE+E + +EKTAF+T  G Y F  MPFG+  AP TFQ +M   L  + G+  +VYLDD++++  + E+H   L EV + + E GL++ PEKC+++K  + +LGHIIS++G+ TDPSK  A++ +  P CV +LR FLG+ +YYR+F++ +A  A  L +L       + +WS+   S F+ LK  LT+AP+L +PD  ++FI+D DAS D +GAVLSQR++   ERV+AY S ++T  E+ YC TR+E+L + +    F+ YLYG+RF +RTDH  + ++ T ++P   Q   W+  L+ LD  VE+R G  H NAD +SRT C  C          VQ      E      K +LL +                                 + ++ R+ + + G++         EE  K+ ++P     E ++ +H  R   H G  +    ++ R+    +   +    R+C  C + K  T   + P++   +    + + +DI GPL +T    +Y+L + D ++K+     +   +  T+ K ++EK++  FG P  +  D G++FE+ ++ E  ++  IK   SSPYH Q NGQ ER  RT+ D+++  + D     W ++LP V    N++  ++TG +PA  + G+++                         +RE+     E+  ++ L+ Q RR            +F   + V + +  R K    +EGPY+V+E +  + Y +R+ + KR  I  + +++K +  R I
Sbjct:   53 EKMLPSEQESSGKHRSALAAILKEFADVLSTSDEDLGRTSLVRHAIHTGDAKPVRCSPRRIPYHQRAQVESLLDEMLRQDVVEPSSSPWASPIVLVRKKDGS-CRFCVDYRQLNNLTRKDAHPLPRIDDTLDALAGAQWFSTLDLASGYWQVEVEPQDREKTAFTTPLGLYQFKVMPFGLCNAPATFQRLMEIALRGLVGSDCLVYLDDVIVFGKTAEEHTARLREVFRRLREVGLKVKPEKCRLMKRRVAYLGHIISEKGIATDPSKTSAVREWPTPTCVSELRQFLGLASYYRKFVNGFANVAAPLHRLLE--KGAEWDWSKACQSAFDTLKYHLTSAPVLAYPDFHRQFIVDVDASGDGLGAVLSQREEKA-ERVVAYASRTLTKAERRYCATRREMLGLVWALREFRPYLYGQRFLVRTDHSCLRWLTTFREP-EGQVARWLESLAELDFEVEHRAGRLHGNADALSRTSCAQCGRLVEGSACAVQAAQLRTEDVAQSFKDQLLAAQQADPEIQLLRQWLVGASWPVECPPECSRDMHVLWQQRRTWVDEDGLIWRHRRGLTAEEGAKQALVPRALRNEVLQSMHDSRYAGHLGERRTLARVRSRFYWPGMSGDVHTWCRTCTQCARRKGPTKNNRAPMQAMAAGYPLQRVGMDILGPLEKTPSGNRYVLVLTDYFTKWTAAFPLANMEASTVAKVLVEKYVAYFGAPDCLHSDQGRSFEASVVLEMCRLFGIKKTRSSPYHPQGNGQAERFNRTLLDMLS-IMVDGNPGQWDDMLPFVMLAYNSSVHESTGVTPAIAMLGRELRLPLDVQIGNPPGGEAQGLPDYIRETRERIDRVHEL-ARDHLKTQQRRQKYLHDRHAKESRFCPNDRVWLAMPRRGKLDRGWEGPYRVVEVMGPQTYRVRHNERKRRTIVVHSDRMKRYHARDI 977          

Query:  936 LLDTGARINVMSVNCFNKLRG-QQLTKSDDKLRCANESTIETIGKTKVQVTIGN-------------VSKEVI----FIVAEKVTPDVIGG--------IELQETFGFRLLKIKDIEASEKDKNYICNIEAKFGRKIKDEERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVT-RGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKGA--MVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTC----------VQCQMAHEEAKKGKIKTRLLDS---------------------------------IREEGRSNI-QHGIV---------EEVRKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKI-------------------------SREKWYGSKEIPIKEELEEQTRR------------KFNVGEEVLVKVETRHKGQDRYEGPYKVIEKVHDRRYILRNEDGKR--IERNVEKLKNFLRRGI 3782
            L+DTG+ + + +      L+  + + K   +L  A  + +E       ++ +GN             +S +++    F+     TPD   G        I  +++    L++++  ++       + +  A+     +  E+++ + ++      S L  I+    +V      D+GRT LV+H I T   +P+   P R P +  +++E  +  +    ++   +SPW +P++ V KK+    R C+D+RQLN +T + A P+P ID+ LD L G+ +FS++DL + Y+QVE+E + +EKTAF+T  G Y F  MPFG+  AP TFQ +M   L  + G+  +VYLDD++++  + E+H   L EV + + E GL++ PEKC+++K  + +LGHIIS++G+ TDPSK  A++ +  P CV +LR FLG+ +YYR+F++ +A  A  L +L       + +WS+   S F+ LK  LT+AP+L +PD  ++FI+D DAS D +GAVLSQR++   ERV+AY S ++T  E+ YC TR+E+L + +    F+ YLYG+RF +RTDH  + ++ T ++P   Q   W+  L+ LD  VE+R G  H NAD +SRT C  C          VQ      E      K +LL +                                 + ++ R+ + + G++         EE  K+ ++P     E ++ +H  R   H G  +    ++ R+    +   +    R+C  C + K  T   + P++   +    + + +DI GPL +T    +Y+L + D ++K+     +   +  T+ K ++EK++  FG P  +  D G++FE+ ++ E  ++  IK   SSPYH Q NGQ ER  RT+ D+++  + D     W ++LP V    N++  ++TG +PA  + G+++                         +RE+     E+  ++ L+ Q RR            +F   + V + +  R K    +EGPY+V+E +  + Y +R+ + KR  I  + +++K +  R I
Sbjct:    2 LVDTGSAVTLANERFIRHLKTLRDVPKPSIRLETATATELEITNACVTEIILGNSVTVQHTVLCVRELSHKILLGWDFMRYHGCTPDPTAGCLRMRQGNIPFRKSHAVALVRVESPQS-----ELMAHHPAQ-----EAMEKMLPSEQESSGKHRSALAAILKEFADVLSTSDEDLGRTSLVRHAIHTGDAKPVRCSPRRIPYHQRAQVESLLDEMLRQDVVEPSSSPWASPIVLVRKKDGS-CRFCVDYRQLNNLTRKDAHPLPRIDDTLDALAGAQWFSTLDLASGYWQVEVEPQDREKTAFTTPLGLYQFKVMPFGLCNAPATFQRLMEIALRGLVGSDCLVYLDDVIVFGKTAEEHTARLREVFRRLREVGLKVKPEKCRLMKRRVAYLGHIISEKGIATDPSKTSAVREWPTPTCVSELRQFLGLASYYRKFVNGFANVAAPLHRLLE--KGAEWDWSKACQSAFDTLKYHLTSAPVLAYPDFHRQFIVDVDASGDGLGAVLSQREEKA-ERVVAYASRTLTKAERRYCATRREMLGLVWALREFRPYLYGQRFLVRTDHSCLRWLTTFREP-EGQVARWLESLAELDFEVEHRAGRLHGNADALSRTSCAQCGRLVEGSACAVQAAQLRTEDVAQSFKDQLLAAQQADPEIQLLRQWLVGASWPVECPPECSRDMHVLWQQRRTWVDEDGLIWRHRRGLTAEEGAKQALVPRALRNEVLQSMHDSRYAGHLGERRTLARVRSRFYWPGMSGDVHTWCRTCTQCARRKGPTKNNRAPMQAMAAGYPLQRVGMDILGPLEKTPSGNRYVLVLTDYFTKWTAAFPLANMEASTVAKVLVEKYVAYFGAPDCLHSDQGRSFEASVVLEMCRLFGIKKTRSSPYHPQGNGQAERFNRTLLDMLS-IMVDGNPGQWDDMLPFVMLAYNSSVHESTGVTPAIAMLGRELRLPLDVQIGNPPGGEAQGLPDYIRETRERIDRVHEL-ARDHLKTQQRRQKYLHDRHAKESRFCPNDRVWLAMPRRGKLDRGWEGPYRVVEVMGPQTYRVRHNERKRRTIVVHSDRMKRYHARDI 1056          

Query:  900 ITVRMNGENFDCLLDTGARINVMSVNCFNKLRGQ-QLTKSDDKLRCANESTIETIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGGIELQETFGFRL-------------LKIKDIEASEKDKNYICNIEAKFGRKIKDEERLIRALEQ-----LKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIE-----EAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIK--GAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQ-----------------------CQMAHEEAK---KGKIKTRLLDSIREEGRSN-------------IQHGIV---------EEVRKKTMIPENELQETIKEIHRLLC--HAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKK 3524
            + V++       L+DTGA   ++  + F ++RGQ +L+  + +L  A  + ++ +G   + + +G+ + ++  IV   +    + GI+  +  GF +             L+I    A     N   ++    G+ +   +R+++ L +     L  ++  KL  +++   N F A ++D+GRT ++KH IVT     NI+P R PL   + +E     + IQ L +N II   NSPW   ++ V KK+   +RLC+D+R+LN V+ R A+P+P IDE L+ L G+ +FS+IDL + Y+QVEL E ++EKTAF T +G + FN MPFG+  AP TFQ +M  VL  +K    +VYLDDI+++S + E+H   L +VL  +++AGL+ N  KC++  +E+R+LGHI+S++G++ DPS  + ++ +  P C+ +++ FLG+ +YYR+FI D+A  A+ L QL      K  +W+    S F+ L+ AL + PIL  PD    FILDTDAS   IGAVLSQRD+ G+E  +AY S ++T  E+ YC+TR+E+LAV  F   F+ YL  ++FTLRTDH ++ ++   K P   Q+  W   L   D  +E+R G  H NAD +SR  C  C +                        Q+  E+     K K    +   IR   RSN             IQ GI+            R + ++P+  ++  + + H+ L   H G+EK  + +++R+      S  ++ V SC  C          + P++   +   +E + +DI GPL  ++   +YIL  ID +SK+     I  Q+ +T+ + ++ ++I R+G P+ I  D G  FE+ + +     L I+   ++PYH   NGQ+ER  RT+  +++  + D     W E+LP+V     A+ Q +T  +P  +VFG++
Sbjct:  356 VPVQVRNRCIRMLVDTGAGRTLLRSDEFARIRGQWKLSPCNVRLLSAEGTALDVMGSVSLPLQVGDRTFDMEVIVVNALQFAGLLGIDFLKQHGFVVDLARGTLNSPKQKLRIPLQSAGRTSGNGAWSVSV--GKPVSLSKRMLQQLVETTGVPLTASQRKKLHGMLSKFRNAFAASEFDIGRTSVLKHDIVTD----NIRPVRHPLRRLAPVERKEVSQLIQRLLDNKIIEPSNSPWAAGIVPVRKKDG-SLRLCVDYRKLNEVSRRDAYPIPRIDETLEALAGARYFSTIDLLSGYWQVELTEAAKEKTAFITHDGLFQFNVMPFGLTGAPATFQRLMEHVLAGLKWNTCLVYLDDIIVFSRTAEEHVEHLSQVLNRLQKAGLKANASKCKLFCKEVRYLGHIVSEKGIEPDPSLTEKMRTYPVPTCLAEVKRFLGLASYYRKFIKDFAAIAKPLHQLTE--KRKPFQWTPECTSAFQKLRTALLSEPILRLPDFDASFILDTDASDTAIGAVLSQRDEHGREHPVAYASRTLTRAEQRYCVTRREMLAVITFTDQFRPYLQ-QKFTLRTDHGSLQWLRDFKNP-DGQWARWQQKLQQYDFDIEHRAGSRHANADTLSRIPCKQCGRSGTEVMGVPVNVVALENLEEMRTSQLDDEDIAPILKAKAAGVVGQEIRCGKRSNSKNLLMLNWHRLAIQKGILVRKWFCDDQSGYRWQVVVPKRMIKPVLDQAHQQLTAGHLGIEKTIERIRERFYWPGYRSDTKKYVASCYECNTRNEPVGKGRAPLQPVVTTRRWEKLAIDILGPLVVSETGNRYILVAIDCFSKFAEAFPIPDQEAKTVTRVLVNEFICRYGVPEAIHTDQGSQFEAAIFQSMCTELGIRKTRTTPYHPSGNGQVERMNRTLGTMLSKVV-DENHRKWDEVLPKVMMAYRASIQSSTRMAPYTMVFGEQ 1294          

Query:  900 ITVRMNGENFDCLLDTGARINVMSVNCFNKLRGQ-QLTKSDDKLRCANESTIETIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGGIELQETFGFRL-------------LKIKDIEASEKDKNYICNIEAKFGRKIKDEERLIRALEQ-----LKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIE-----EAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIK--GAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQ-----------------------CQMAHEEAK---KGKIKTRLLDSIREEGRSN-------------IQHGIV---------EEVRKKTMIPENELQETIKEIHRLLC--HAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKK 3524
            + V++       L+DTGA   ++  + F ++RGQ +L+  + +L  A  + ++ +G   + + +G+ + ++  IV   +    + GI+  +  GF +             L+I    A     N   ++    G+ +   +R+++ L +     L  ++  KL  +++   N F A ++D+GRT ++KH IVT     NI+P R PL   + +E     + IQ L +N II   NSPW   ++ V KK+   +RLC+D+R+LN V+ R A+P+P IDE L+ L G+ +FS+IDL + Y+QVEL E ++EKTAF T +G + FN MPFG+  AP TFQ +M  VL  +K    +VYLDDI+++S + E+H   L +VL  +++AGL+ N  KC++  +E+R+LGHI+S++G++ DPS  + ++ +  P C+ +++ FLG+ +YYR+FI D+A  A+ L QL      K  +W+    S F+ L+ AL + PIL  PD    FILDTDAS   IGAVLSQRD+ G+E  +AY S ++T  E+ YC+TR+E+LAV  F   F+ YL  ++FTLRTDH ++ ++   K P   Q+  W   L   D  +E+R G  H NAD +SR  C  C +                        Q+  E+     K K    +   IR   RSN             IQ GI+            R + ++P+  ++  + + H+ L   H G+EK  + +++R+      S  ++ V SC  C          + P++   +   +E + +DI GPL  ++   +YIL  ID +SK+     I  Q+ +T+ + ++ ++I R+G P+ I  D G  FE+ + +     L I+   ++PYH   NGQ+ER  RT+  +++  + D     W E+LP+V     A+ Q +T  +P  +VFG++
Sbjct:  356 VPVQVRNRCIRMLVDTGAERTLLRSDEFARIRGQWKLSPCNVRLLSAEGTALDVMGSVSLPLQVGDRTFDMEVIVVNALQFAGLLGIDFLKQHGFVVDLARGTLNSPKQKLRIPLQSAGRTSGNGAWSVSV--GKPVSLSKRMLQQLVETTGVPLTASQRKKLHGMLSKFRNAFAASEFDIGRTSVLKHDIVTD----NIRPVRHPLRRLAPVERKEVSQLIQRLLDNKIIEPSNSPWAAGIVPVRKKDG-SLRLCVDYRKLNEVSRRDAYPIPRIDETLEALAGARYFSTIDLLSGYWQVELTEAAKEKTAFITHDGLFQFNVMPFGLTGAPATFQRLMEHVLAGLKWNTCLVYLDDIIVFSRTAEEHVEHLSQVLNRLQKAGLKPNASKCKLFCKEVRYLGHIVSEKGIEPDPSLTEKMRTYPVPTCLAEVKRFLGLASYYRKFIKDFAAIAKPLHQLTE--KRKPFQWTPECTSAFQKLRTALLSEPILRLPDFDASFILDTDASDTAIGAVLSQRDEHGREHPVAYASRTLTRAEQRYCVTRREMLAVITFTDQFRPYLQ-QKFTLRTDHGSLQWLRDFKNP-DGQWARWQQKLQQYDFDIEHRAGSRHANADTLSRIPCKQCGRSGTEVMGVPVNVVALENLEEMRTSQLDDEDIAPILKAKAAGVVGQEIRCGKRSNSKNLLMLNWHRLAIQKGILVRKWFCDDQSGYRWQVVVPKRMIKPVLDQAHQQLTAGHLGIEKTIERIRERFYWPGYRSDTKKYVASCYECNTRNEPVEKGRAPLQPVVATRRWEKLAIDILGPLVVSETGNRYILVAIDCFSKFAEAFPIPDQEAKTVTRVLVNEFICRYGVPEAIHTDQGSQFEAAIFQSMCTELGIRKTRTTPYHPSGNGQVERMNRTLGTMLSKVV-DENHRKWDEVLPKVMMAYRASIQSSTRMAPYTMVFGEQ 1294          

Query:  897 SITVRMNGENFDCLLDTGARINVMSVNCFNKL-RGQQLTKSD--DKLRCANESTIETIGKTKVQVTIGNVSKEVIFIVAEKVTP--DVIGGIELQETFGFRLLKIKDI-------------EASEKDKNY----ICNIEAKFGRKIKDEERLIRAL-EQLKINEDSK--LKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGE-PINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKG--AMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKC----DTCVQCQ--------------MAHEEAKKGKIKTRLLDSIREEGRSNIQHGIVEEVRKKTMIPENELQETIKEI----HRLLCHAGVEKIADYMKDRYVGKHL--------------WSKIQEIV----RSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKI 3527
            ++ + + G+    ++DTG+  +++    ++++ R Q++ +S    K   AN  T    G  ++   +G    +  F V E       ++ G++     G  L   KD+             E      +Y    +C  +  +     +EE+ I  L E   I   +K  L ++++   +V       +GRT +V H I T    PI  KPY+  +  +  I+EAI+++   GI+R   SPW +P++ V KKE   +R C+D+R++N+ T   A+PMP + E+L+ L G+  FS++DL + Y+QV LE +S  KTAF T  G Y F  +PFGI  A  TFQ +M  VL  +KG    VY++DI++YSS+ E+H   L EV + + +AGL +N  KC +++  + FLGH+IS EG+ T+P K++AIQ F +P  +K+L+ FLG+  +Y RFI+ ++++A +L  L     N    W++     FE +K AL TAP+L  P+  + F + TDAS   +GAVLSQ   DG E V+AY S  +   E+ Y    KE LAV +    ++ YL GR FT+ TDH A++++    KP TS+   W   L + D  V+YRKG  +   D +SR            CQ              +A  +   G ++ +  ++  +E R +  H + +       +P  +L  T++ +    HR       E    Y  D  +  HL              W  I+  V    +SCEICQK K         ++     E   ++ VD+ GPL ++  + +++L I+D  SK+  +  + +     I + +++    R+G P  +  D G  F S ++    +   +    ++ YH QTN   ER  RT++ +I + ++D+ +  W + +PE  F +N+  Q++TG +PAE+  G+K+
Sbjct:  427 TLPLSVRGQQVTAMIDTGSTFSLIQEGTWDRMKRTQEVWRSGRGQKFILANGQTQTAKGVVELDCELGKCQAKRPFYVMENKDHVFSLVLGLDFLHDTGLILDFQKDVYILPGGDTVPFGGEGESPPFSYADMRLCIAQEDYVPLDYEEEQEINKLVEGADITSQAKQDLHKLLSQWPSVCTNQ---LGRTMIVLHHITTNDNLPIRQKPYKVSIEKQQLIKEAIEDMQRRGIVRPSTSPWASPVVLVPKKEG-GVRFCVDYRRMNSKTHLDAYPMPQVQEILESLHGAAIFSTLDLKSGYWQVGLEPDSIPKTAFITCQGLYEFTVLPFGIKNAAATFQRLMDSVLVNLKGKSCFVYINDIVVYSSTIEQHLGHLEEVFRCLHQAGLTLNLRKCNLLQRSLIFLGHVISGEGICTEPGKVEAIQAFPEPRSIKELQRFLGMAGWYHRFITHFSERAAILNALKK--KNAPWIWTQECQKAFEDIKQALITAPVLTPPNFSEPFQIQTDASDQGLGAVLSQ-GTDGLEHVVAYASRLLQGAERNYSTAEKECLAVVWAVEKWRVYLEGRHFTVITDHSALSWVFNHPKP-TSRLTRWAIRLQTFDFSVQYRKGKCNIVPDTLSRIPDRMTEGVMAPCQVTGSSDGLPVDWAEIARAQEVDGTLQPQRDETGNQETRKDRIHFVTKNDILFRAVPNQQLGHTLQVVVPVQHR-------EAFLQYAHDNPLSGHLGQMKTLLRLLNIAYWPSIRRDVWTYCKSCEICQKYKPRISKLSGRLQSTPVVEPGYMLGVDLMGPLPKSPRQNEHLLVIVDYCSKWVEMFPLREAKTSQIVQILIKDIFTRWGTPAYLVSDRGAQFTSRLLHATCRQWGVVQKLTTAYHPQTN-LTERVNRTLKTMIASYVKDKHRL-WDQWIPEFRFAINSAWQESTGFTPAEVALGRKL 1354          

Query: 1278 ERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQ-PLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLG--KIKGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLE-----------WSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEK---GYCITRKELLAVYYFCIH-FKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSR---------TKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIVEEV----------RKKTMIPENELQETIKEIHRLLC------------------------------------------------HAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFG--KKISREKWYGSKEIPIK-EELEE 3584
            E +    E L   +  + + +     N+F   + D+G T L+ H+I    E    +PYR+ P +  S ++  IQ L ++ +IR+ +SP+++P++ V KK+   +RLC+D+RQLNA T R ++P+P I+E LD L G+ +FS++DL + Y QV +EE+ + KTAF T  G + FNRMPFG+  APGTFQ +M ++ G  + +  ++YLDD++++S + E+H   L EV   +++  L++   KCQ  + ++ +LGH++S EGV TDP+KI+ ++ +  P+ + +LRSFLG  +YYRRF+  ++K A  L +L  G S  + +           W       F+ LK  LT+ P+L + D  K FI++ DAS   +GAVLSQ +++GK R IA+ S  +   E+    Y   + ELLAV +     F+ YL G +FT+ TD+  ++ + T K  + +  Q W + L+S +  ++YR G ++QNAD +SR         TK    V  +  HEE  +  ++ +    +   GRS    G+++            R +   P  E ++T+  + ++L                                                 H G E+    ++DR    ++   ++   + C+ C   KA+    +       +    EI+ +D    L      K+ +L + D ++KY    A   Q   T+   +++ W  RFG P  I  D G+ FES ++++  K+  I+   ++ Y  Q NGQ ER  RT+ DL+  TL   +K  W   LP++ F  N T  +TTG++P  ++FG   ++  +   G+ E+    E LEE
Sbjct:  255 EYVTSDFEGLTDLQAQRARALFQKYSNIFAKSEGDLGCTSLISHEIPLLDEVPVRQPYRRIPPSQYSTVKAHIQQLLDSRVIRESSSPFSSPIVLVTKKDG-SLRLCVDYRQLNAKTRRDSYPLPRIEESLDALCGAKWFSTLDLASGYNQVPVEEKDKSKTAFCTPFGLFEFNRMPFGLCNAPGTFQRLMERIFGDCRYQSVLLYLDDVIVFSQTVEEHLERLEEVFSRLQKQNLKVKLSKCQFFQHQVSYLGHVVSAEGVTTDPAKIEVVKEWKSPSHLAELRSFLGFASYYRRFVEGFSKLAAPLHRLVGGLSGPRRKGKTPKTSLAAFWDAECEQAFQSLKDRLTSTPVLAYADFNKPFIVEVDASHGGLGAVLSQ-EQEGKVRPIAFASRGLRPTERNMENYSSMKLELLAVKWAVTEKFREYLLGHQFTIYTDNNPLSHLQTAK--LGAVEQRWASQLASFNFTIKYRPGKHNQNADALSRQYLERFAVGTKVPPLVM-EAVHEE--RSALENQCRQVVAFPGRSPSDLGVLQRADPVIGPVWKFRSEGRRPRTEERDTLCNLSKVLIRQWDRLVEREGVLYRRAYPSGRGSEYFQLLLPQCLQKEVLHSVHDDHGHQGTERTLQLLRDRCFWPNMTQDVERWCQQCQRCTLGKAVQPKVRAFQGTLQAAHPNEILAIDFTI-LEPASDGKENVLILTDIFTKYTQAIATKDQRASTVAWALVQHWFHRFGPPVRIHSDQGRNFESLLIKQLCKVYSIQKSRTTSYRPQGNGQCERFNRTLHDLLR-TLPVEEKRHWPRHLPQLTFAYNTTPHQTTGQTPHFLMFGYHPRLPVDFLLGTGEVTASTEPLEE 1102          

Query: 1269 KDEERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQ-PLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLG--KIKGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSG-----------PSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEK---GYCITRKELLAVYYFCIH-FKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCV------QCQMAHEEAKKGKIKT-RLLDSIREEGRSNIQHGIVEEV----------RKKTMIPENELQETI--------KEIHRLLCHAGV----------------------------------------EKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFG 3518
            K    L+  +E L   + + +  +     ++F   + D+G T L+ H+I    E    +PYR+ P +    ++  IQ L ++ +IR   SP+++P++ V KK+   +RLC+D+RQLNA T R A+P+P I+E LD L G+ +FS++DL + Y QV + E+ + KTAF T  G + FNRMPFG+  AP TFQ +M ++ G  + +  ++YLDD++++SSS E+H   L EV   +++ GL++   KC   + ++ +LGH++S+EGV TDP+KI A++ + +P+ + +LRSFLG  +YYRRF+  ++K A  L QL              P      W E     F+ LK  LT+AP+L + D  K FI++ DAS   +GAVLSQ +++GK R IA+ S  +   E+    Y   + ELLAV +     ++ YL G   T+ TD+  ++ + T K   T   Q W + L+S + +++YR G ++QNAD +SR   D           +M   E++    KT +  + +   GRS +   +++E           RK+   P  E +E +        ++  RLL   GV                                        E+    ++ R     +   ++   + C  C  +KA+    +       +    EI+ +D       + GR+  +L + D ++KY        Q   T+ + +++ W  RFG P  I  D G+ FES ++++   M  I+   ++ Y  Q NGQ ER  RT+ DL+  TL   +K  W   L  + F  N T  +TTGK+P  ++FG
Sbjct:  268 KSPHGLLSDIEGLSEEQMAAVSLLFDQYQDIFAQTEGDLGCTTLLTHEIPLLDEVPVRQPYRRIPPSQYEAVKLHIQQLLDSKVIRNSASPYSSPIVLVTKKDG-SLRLCVDYRQLNAKTRRDAYPLPRIEESLDALAGAKWFSTLDLASGYNQVPVSEKDRYKTAFCTPFGLFEFNRMPFGLCNAPATFQRLMERMFGDCRYQSVLLYLDDVIVFSSSVEQHLERLAEVFSRLQKQGLKVKLSKCHFFQPQVNYLGHVVSREGVATDPAKIDAVRGWRRPSHLAELRSFLGFASYYRRFVEGFSKLAAPLHQLVGKLGGARRKGKTLPVPLAASWDERCEKAFQSLKERLTSAPVLAYADFSKPFIVEVDASHGGLGAVLSQ-EQEGKVRPIAFASRGLRPAERNMDNYSSMKLELLAVKWAVTEKYREYLLGNEVTILTDNNPLSHLQTAKLGATE--QRWASQLASFNFKIKYRPGKSNQNADALSRQYVDRFAIGTKVPPLRMELLESEPMVHKTGQCTEMVALAGRSALDLHLLQEADPVIGPVCKFRKEGRYPRAEEREALSSPTKALFRQWDRLLEKDGVLYRAVQPSGGGPETCQLLLPKHLQEEVLSSVHDDHGHQGVERTLKQLQSRCFWPGMAKHVERWCQQCRRCVLSKAVQPKIRAFQGTLQATRPHEILAIDFTLLEPASDGREN-VLVLTDVFTKYTQAIPTRDQRASTVAQVLVQHWFHRFGLPSRIHSDQGRNFESMLIQQLCNMYGIQKSRATAYRPQGNGQCERFNRTLHDLLR-TLPQSEKRRWPHYLSPMVFAYNTTPHQTTGKTPYYLMFG 1094          

Query: 1275 EERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVT---RGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKGA--MVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSR-----TKCDTCVQ----------CQMAHEEAKKGKIKTRL-LDSIREEGRSN---------------------------------------IQHGIVEEVRK---------KTMIPENELQETIKEIHRL--LCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKI 3527
            EE L R+   L   +  +L+++I      F   + +  RT L  H I T   +         R         E+ ++++   G+I   +SPW+ P++   KK+  + R C+D+R+LNAVT+  ++P+P ID+ LD L GS +FSS+DL + Y+QV L E  +EKTAFS  +  + F  +PFG+  +P TF+ +M +VL  I  +  +VYLDD++ + +  +   + L  VL AI+ A L++NP KC ++++ + FLGH++S  GV+TDP K +A++++  P   K +RSF+G+ +YYRRFI  +         L          WS+     F  LK  L  AP+L + ++++  +    AS   +GAVLSQ  +DG ERVIAY S  +   E+ YC+T +ELLAV     HF+ Y+YG  F LRTDH ++ ++M  ++P   Q   WI+ +      V +R G +H NAD +SR       C  C +          C     +   G +  ++ ++ IR+  R++                                       +  G++  V +         + +IP       ++ +H      H GV K    ++ R+      + ++  V  C++C   K      + P+         E + VD+ GP   T    +Y+L  +D ++K+    A+  Q   T    ++ ++  RFG P+E+  D G+ FES +M E  ++L I    ++P H Q++G +ER F        A +  + + DW + LP V     +  Q+TTG +PA ++FG+++
Sbjct:   85 EEMLERSCVGLSEPQQLRLRDLIERFRASFAVSERECTRTSLAFHSINTGDAQTSGWQTAAARLAFAKRVAAEQLVRDMASAGVIEPSSSPWSAPVVLA-KKKDGNWRFCVDYRRLNAVTKLDSYPLPRIDDTLDQLSGSAWFSSLDLRSGYWQVPLAEGDREKTAFSLGSALWHFTVLPFGLCNSPATFERLMERVLSGIPRSCCVVYLDDVMAHGTDFDSALSHLEVVLGAIQAANLKLNPAKCNLLRQRVNFLGHVVSGAGVETDPKKTEAVRDWPVPRNAKMVRSFVGLASYYRRFIRGFRDVGGNASHLTR--PGVTFRWSDEAERAFGELKSRLCNAPVLAYRNVREASLWIRIASDRGLGAVLSQV-QDGSERVIAYYSRRLDKAERNYCVTCRELLAVVEGLKHFRPYVYGVPFLLRTDHASLQWLMRFREP-EGQLARWISRIQEFSFEVVHRPGRSHGNADALSRRPCVAVDCKHCARAEEKSAETAHCAAVSADVTGGVVVAQVSVEQIRDAQRADRDLMWAVHALEANVTPSWEEVVPLGPVAKALRSNWASFSLSDGVLCHVWEDPANGQRVFRVVIPRALRDSVLRGVHGSPGAGHFGVTKTLKRLRQRFYWPGCRTDVELFVHCCDVCAAKKGPARAPRAPLHPYQCGGPMERVAVDVLGPFPVTDSGNRYVLVAMDYFTKWPEAYAVPDQGAVTTADVLVREFFCRFGVPEELHSDQGRNFESEVMAEVCRILGIHKTRTTPLHPQSDGLVER-FNCTLAAQLAMVSSKGQRDWDKHLPVVLLACRSAVQETTGFTPALLMFGREL 900          

Query: 1305 LKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKI-VTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKG--AMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTR 2756
            L  N+  +L ++++  G+VF     D+GRT LV+H I +  G P+  +P R     + + +  IQ   E+G+    NS W +P++ V KK++   RLC+D+R LNA T + A+P+P I + L+ L  + +FS++DL + Y+QV L   +++  AF ++ G + +N MPFG+  AP TFQ +M +VL  ++    +VYLDDI++      +    L +V     +A L++ P KC + + E+ +LGHI+S +G+ TDP K++ +Q + +P CV ++R F+G+  YYRRF+ D+A  A+ L +L     + + +W+    + FE LK +LT+ P+L +P      ILDTDAS   IGAVLSQ  +DG ERV+AYGS  ++S E+ YC TR+ELLAV  F  HF+ YL GR F +R+DH ++ +++  K+P   Q   W+  L+  D +V +R G +HQNAD++SR  C T   C M        K+  R
Sbjct:   35 LSANDRLELAQLLSTYGDVFSTGPTDLGRTSLVQHDIQLLPGPPVKQQPRRMAFEKQIESDAQIQQSLESGLASPSNSSWASPIVLVRKKDQT-YRLCVDYRALNARTVKDAYPLPRIQDTLETLSTAKWFSTLDLASGYWQVALTPRARKAVAFCSRKGLFTWNVMPFGLCNAPATFQRLMDRVLAGLQWETCLVYLDDIILLGKDVPEILQRLAQVFDRFRQANLKLKPTKCCLFRREVSYLGHIVSAQGIATDPEKVRKVQQWPQPTCVSEVRQFVGLAAYYRRFVQDFATIAKPLHELTK--KHVRFQWTPECQTAFEELKSSLTSTPVLGYPRDHGNLILDTDASNFGIGAVLSQV-QDGAERVLAYGSRRLSSTEQNYCTTRRELLAVVEFTRHFRQYLLGRPFIVRSDHSSLRWLVNMKEP-EGQLARWLEKLAEYDFQVVHRPGHHHQNADVMSRRPCRTTCPCNMTDPADVACKVTHR 516          

Query: 2814 EVRKKTMIPENELQETIKEIH--RLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKIS 3530
            E   + ++P    Q+  +++H   +  H GVE+    ++ RY    +   I    R+C  C        T + P+         E I +D+ GP+ ET    +YIL   D ++K+    A+      T+ + +  +W+ R+G P+ +  D G  FES + ++  ++L ++   ++P+  Q++GQ+ER   T++ ++ AT  +R   DW  + P       ATK  +TG +P  ++FG++++
Sbjct:  641 EFHPQMILPRVFRQDVQQQMHDGPVGGHFGVERTLARVQTRYYWYQMREDITLWCRTCTSCAAKARPPKTPQAPMGTVRVGAPMERIAIDLMGPMNETDRHNRYILVAQDYFTKWVEAYALPNDQAVTVAEVLTSEWVCRYGAPQTLHSDQGSNFESEVFQKMCELLGVEKTRTTPFRPQSDGQVERFNATLQKIL-ATTAERCHWDWDLMTPFAVMAYRATKHSSTGLTPNMMLFGRELT 880          

Query: 2820 RKKTMIPENELQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHH-QTNGQIERQFRTIRDLIN-ATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKK 3524
            RK+ ++   E + +I +      H G  +    +++ Y  K + + I++ + +CEIC K K+   ++   VK   +   +E++ +D+ GP   T    +++L I+D ++K+  LT +T Q    +   +      RFG PK++  +  + + + +  E  +     +C      H   NG      + +RD ++ AT + R   DW   L +  F  + +K   T  SP  ++ G++
Sbjct:   59 RKRLVVMNEEDKRSILQRVHGADHCGQTRTRKLLEEHYYWKGMVNDIRDYINACEIC-KQKSYKRSSISHVKLLKASYPWEVLGMDLLGPFPATSRAHRFVLLIVDYFTKWAELTPMTDQSAAHVVAALTTA-FHRFGFPKKLFCNVSEEYVAQINEEMFR--HFPMCSGLAISHLWANGAHRGTSQALRDCVSKATGRHR---DWELQLEQRLFEYHTSKHSATRYSPFYLMLGRE 288          

Query: 2814 EVRKKTMIPENELQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQF-------RTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGK 3521
            E R+  ++ E+E +  +  +H    H G +K    ++  Y    + S ++ ++ SC +C+   +  +     +K   +   +E++ +D+ GPL  T    +Y+L +ID +SK+     + ++ +E +  + L     R+G P+++    GK F + + +  T     + C  SP   Q +  +  +        + ++  +N  +  +  +DW   + +  F     K  TT  SP  ++FG+
Sbjct:   66 ERRRMVVMDEDEKRNILMSVHGA-GHFGQKKTILKLEADYYWLGMISDVKNLIASCGVCRNKGSRRVAMPS-MKLLKASGPWEVLGLDVLGPLPVTSRANRYLLLLIDYFSKWAEAVPLIEKSQEHV-ASALTVVFCRYGFPRKVFSSLGKEFVTQVNKSSTLSRAYQRC--SPSQTQVHAHVSVRVALNKATNQALKGCVN-LVASQHPSDWESRVEQSLFEYRVGKHSTTQYSPFYLMFGR 302          

Query: 2814 EVRKKTMIPENELQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFS------------SPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGK 3521
            E R+  ++ E+E +  +  +H    H G +K    ++  Y    + S ++ ++ SC +C+   +  +     +K   +   +E++ +D+ GPL  T    +Y+L +ID +SK+     + ++ +E +  + L     R+G P+++    GK F    + +  K+   K C S            + +H  TN       + ++  +N  +  +  +DW   + +  F     K  TT  SP  ++FG+
Sbjct:   66 ERRRMVVMDEDEKRNILMSVHGA-GHFGQKKTILKLEADYYWLGMISDVKNLIASCGVCRNKGSRRVAMPS-MKLLKASGPWEVLGLDVLGPLPVTSRANRYLLLLIDYFSKWAEAVPLIEKSQEHV-ASALTVVFCRYGFPRKVFSSLGKEF----VTQVNKIQHKKWCISHTLQNLCETRGPAGWHKATN-------QALKGCVN-LVASQHPSDWESRVEQSLFEYRVGKHSTTQYSPFYLMFGR 298          

Query:  205 KSYARVVYQEPQGRVQYKKKEQREESIRREMPECWLCHKIGHTKIDCP-----IKGKIECWTCHRSGHISRNCPDKKAP----RCFGCGKEGHIRRLC 471
            KS+    Y+  +G    ++    ++S+      C+ C K GH   +CP       G   C+TC + GH++R C          +C+GCG+ GH++R C
Sbjct:    4 KSFTDGCYRCGEGGHIARECPLPQDSVSSNTAACYNCGKGGHIARECPEGRQDRGGGPSCYTCGKQGHLARECSSGGGGPGDNKCYGCGQRGHMQRDC 101          

Query:  304 CWLCHKIGHTKIDCPIKGKIECWTCHRSGHISRNCPDKKA---PRCFGCGKEGHIRRLCQEIRCERCSRNGHRSEEC 525
            C++C KIGH   DC    +  C+ C++ GH+  +C   +     +C+ CG+ GH+R  C   RC  C++ GH S EC
Sbjct:    6 CYVCGKIGHLAEDC--DSERLCYNCNKPGHVQTDCTMPRTVEFKQCYNCGETGHVRSECTVQRCFNCNQTGHISREC 80          

Query:  292 EMPECWLCHKIGHTKIDCPIKGKIECWTCHRSGHISRNCPDKK--------------AP----------------RCFGCGKEGHIRRLCQEIR-CERCSRNGHRSEEC 525
            E  +C+ C + GH + +C ++    C+ C+++GHISR CP+ K               P                +C+ CG+ GH+ R CQ  R C  C+  GH S++C
Sbjct:   45 EFKQCYNCGETGHVRSECTVQ---RCFNCNQTGHISRECPEPKKTSRFSKVSCYKCGGPNHMAKDCMKEDGISGLKCYTCGQAGHMSRDCQNDRLCYNCNETGHISKDC 150          

Query:  304 CWLCHKIGHTKIDCPIKGKIE---CWTCHRSGHISRNCPDKKAPRCFGCGKEGHIRRLCQE---------IRCERCSRNGHRSEEC 525
            C+ C+K GH + DC +   +E   C+ C  +GH+   C      RCF C + GHI R C E         + C +C    H +++C
Sbjct:   25 CYNCNKPGHVQTDCTMPRTVEFKQCYNCGETGHVRSEC---TVQRCFNCNQTGHISRECPEPKKTSRFSKVSCYKCGGPNHMAKDC 107          

Query:  157 TLMDK-VEKQREQINSMKSYARVVYQEPQGRVQYKKKEQREESIRREMPECWLCHKIGHTKIDCPIKGKIECWTCHRS-GHISRNCPDKKAPRCFGCGKEGHIRRLC----QEIRCERCSRNGHRSEEC 525
            T  DK V    E++NS  +  R +    QGR  +   +  +++I+   P+C  C + GH K DCP    I C  C  +  H SR+CP  KA +C  C + GH R  C    ++++C  C    H  E C
Sbjct:   16 TPPDKLVAPSIEEVNSNPNELRAL--RGQGRY-FGVSDDDKDAIKEAAPKCNNCSQRGHLKKDCP---HIICSYCGATDDHYSRHCP--KAIQCSKCDEVGHYRSQCPHKWKKVQCTLCKSKKHSKERC 136          

Query: 1890 DDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNY 2147
            DD++ + SS E+H   +  +L+A+  +G + + +K Q     ++FLGH+I + GV+  P K+  I+ +  P   ++LR F+G+C +
Sbjct:    1 DDVICFHSSFEEHLRGIERMLQAVRASGFK-SIKKSQFATRSVKFLGHVIDQNGVRPQPEKLD-IRQWETPTNEEELRKFIGVCTF 84          

Query:  304 CWLCHKIGHTKIDCPIKGKIECWTCHRSGHISRNCPDKKAPRCFGCGKEGHIRRLCQ-EIRCERCSRNGHRSEEC 525
            C  CH++GH    CP++G+  C+ C  +GH+   CP    P C  C + GH    C    RC RC   GH    C
Sbjct:   19 CGYCHQVGHPISTCPVRGR--CFRCGAAGHVVARCPAPAVP-CGYCHQVGHPISTCPVRGRCFRCGAAGHVVARC 90          

Query:  304 CWLCHKIGHTKIDCPIKGKIECWTCHRSGHISRNCPDKKAPRCFGCGKEGHIRRLC--QEIRCERCSRNGHRSEECYTKMR 540
            C+ C   GH    CP    + C  CH+ GH    CP +   RCF CG  GH+   C    + C  C + GH    C  + R
Sbjct:    1 CFRCGAAGHVVARCP---ALACGYCHQVGHPISTCPVRG--RCFRCGAAGHVVARCPAPAVPCGYCHQVGHPISTCPVRGR 76          

Query:  939 LDTGARINVMSVNCFNKLRGQQLTKSDDKLRCANESTIETIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGG 1154
            LDTGA  + +S+N +NKL  +Q  +S  +LR  N+STI+ +G+ K+  T   ++++V F + ++    ++ G
Sbjct:  115 LDTGATCSTLSLNDYNKLTKKQPEQSQTELRTYNQSTIKPMGQVKLHCTANGITRKVHFQIIKEAPTSLLSG 186          

Query:  250 QYKKKEQREESIRREMPECWLCHKIGHTKIDCPIKGK-IECWTCHRSGHISRNCPDKKAPRCFGCGKEGHIRRLC 471
            +Y K+E+R   IR     C  C++ GH  +DCP   K I+C  C   GH  R+CP++    CF C + GH  R+C
Sbjct:    2 RYYKEEKRSMYIR-----CHNCNERGHMAVDCPDPKKVIKCCLCGGQGHYKRSCPNE---LCFNCDQPGHQSRVC 68          

Query: 1296 LEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKI-VTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLG--KIKGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCS----------GPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEK---GYCITRKELLAVYYFCIH-FKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTC--------------------VQCQMAH---------------EEAKKGKIKTRLLDSI-------------REEGRSNIQHGIVEE----------VRKKTMIPENE------------LQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKK 3524
            LE L   +  K + ++    NVF A + D+G T L+ H+I +    P+  +  R P +    +++ I  L  +G+IR+ NSP+ +P++   KK+   +R+C+D+RQLN+ T R AFP+P IDE LD L G+ +F+++DL + Y QV + E  + KTAF T  G + +NRMPFG+  APGTFQ +M ++ G  + +  ++YLDDI+++SS+ ++H   L  VL  +++  LR+   KC   ++E+R+LGH+IS +GV TDP KI+A+  +  P+ V +LR+FLG  +YYRRF+  +A+ A  L +L              S+ +  W+      F+ LK  LT+AP+L + D    F L+ DAS + +GAV  Q ++ G  R IAY S  + + E+    Y   + E LA+ +     F+ YL G    + TD+  ++++ T K  +    Q W+  L++ D  ++YR G  ++NAD +SR    +                     VQ  +AH                E +  ++   +L S+               EG S +   ++ +          V ++ ++P++             + E ++++H+   H G+E+    ++ R     +   +    ++CE CQ  K  + +   P+    +    E++ +D    L  ++   + +L + D +SKY V      Q   T+ K ++ +W  +FG P  +  D G++FES ++++   +  I+   ++PYH   NGQ ER  RT+ +L+ A LQ  +K DW   LP+V F  N T  +TTG+SP   +FG++
Sbjct:  175 LETLPAEDRGKAQALLQKYANVFAAHEGDLGCTTLMTHEIPLLDDAPVRQRHRRIPPSEYEAVKDHINQLLASGVIRESNSPYASPIVLARKKDGS-LRMCVDYRQLNSKTRRDAFPLPRIDESLDALSGARWFTTLDLASGYNQVPVTEGDRAKTAFCTPFGLFEWNRMPFGLCNAPGTFQRLMQRIFGDQQCQSVLLYLDDIVVFSSTIDEHLERLELVLGRLQQEKLRVKLPKCAFFQQEVRYLGHVISDQGVSTDPHKIEAVAGWQPPSTVSELRTFLGFASYYRRFVEGFARLAAPLHRLVGELDGTKSRRRKASSLQGHWTTECQQNFDALKQKLTSAPVLAYADFTLPFFLEVDASHNGLGAVFPQ-EQGGSVRPIAYASRGLKATERNMQNYSSMKLEFLALKWAMTEKFREYLLGHHCVVFTDNNPLSYLSTAK--LGEMEQRWVAQLAAFDYEIKYRSGRVNRNADALSRHPNHSSAEVGNMAPGSSLPRDLQQVQVQPVLAHCEMEQLMPVFPQRTTAEVQDLQVSDPVLASVLPFWRDQRYPNYSEREGLSKVALTLLRQWKNLAEVDGLVYRRVLMPDSGQEVFQLLLPEILIPEVLEQVHQHHGHQGIERTLALLRARCYWPGMSKDVAHWCQACERCQLAKDNSRSHSAPLGHLIASRPNELVAMDFTI-LEPSRTGVENVLVLTDVFSKYTVAIPTRDQRAATVAKVLVAEWFSKFGVPARLHSDQGRSFESQLIQQLCGLYGIEKSRTTPYHPAGNGQCERFNRTLHNLLRA-LQVTRKRDWHSCLPQVTFCYNTTPHQTTGESPFFFMFGQQ 998          

Query: 1296 LEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKI-VTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKGA--MVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKL----------EWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKG---YCITRKELLAVYYFCIH-FKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKG----------------------------------------------------INHQNADMVSRTKCDTCV---------QCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIV---------EEVRKKTMIPENELQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGK--KISREKWYGSKEIPIKEELEE-----QTRRKF---NVGEEVLVKVETRHKGQD 3656
            L  L   E  K++ ++     VF   + D+G T L+ H+I +    P+  +  R P +     +E I NL ++ +IR+ +SP+ +P++ + KK+   +RLC+D+RQLN+ T + AFP+P I+E LD L G+ +FS++DL + Y+QV + E  + KTAF T  G + +NRMPFG+  AP TFQ +M ++ G+ +G   ++YLDDI+++SS+ E+H   L  VL+ ++  GL++   KC   + ++ +LGH+IS +GV TDP K++A+ N+  P  V +LRSF+G  +YYRRF+  +AK A  L +L +     K+           W+E     FE LK  LTT P+L + D  + FIL+ DAS   +GAVLSQ +++GK R IAY S  +   E+    Y   R E LA+ +     F+ YL G++  + TD+  ++++ T K  + +  Q W   L++ D+ + YR G                                                     +H  +DM S    D  +         Q + + EE ++  + +  L  +R+  R   Q G++          E   + ++P +  +E +  +H+   H GV++  D ++ R     + +++ E    CE CQ  K      + P+    + +  EI+ +D    L  T    + +L I D +SKY +  A   Q   T+ + ++ +W  +FG P  I  D G++FES ++++   +  ++   ++PYH + NGQ ER  RT+ DL+  TL   +K DW   LP++ ++ N T   +TG+SP  ++FG+  ++  +   G  + P++  ++E     + R K       E++L   + R +G D
Sbjct:  301 LSALSAGEQEKVRALLGKYLTVFSLHEGDLGCTSLITHEIPLVDDAPVRQRYRRIPPSDYVAAKEHINNLLQSQVIRESSSPFASPIVLIRKKDG-GLRLCVDYRQLNSRTRKDAFPLPRIEESLDALSGARWFSTLDLASGYHQVAVAEADRPKTAFCTPFGLFEWNRMPFGLCNAPSTFQRLMQRMFGEQQGQSLLLYLDDIIVFSSTIEQHLERLELVLERLQLEGLKVKLAKCAFFQHQVHYLGHVISDQGVSTDPGKVEAVANWEPPTTVFQLRSFIGFASYYRRFVEGFAKLAAPLHRLVAELEGNKVRKKSARGLTNHWTEECQRSFEALKAKLTTTPVLAYADFSRPFILEVDASNGGLGAVLSQ-EQEGKVRPIAYASRGLRPTERNPVNYSSMRLEFLALKWAVAEKFREYLLGQKCIVYTDNNPLSYLSTAK--LGAMEQRWAAQLAAFDLEIRYRSGRSNRNADALSRQHFPDMQAWRDVLPGSCLPMSLQQVQQTETVGTTQATMVALPHHSPSDMASLQGADPVLKEFLPFWERQTRPSPEERRQ--LSSPTLALLRQWNRLVEQGGVLYRRVFRDDGGEAVLQILLPGSIREEVLTAVHQQHGHQGVDRTLDLLRQRCYWPGMSAEVAEWCSQCERCQVAKVTRPAARAPMGHLLASKPNEILAMDFSV-LEPTTSGIENVLVITDIFSKYTMAVATRDQRAATVAQVLVTEWFSKFGVPARIHSDQGRSFESALIQQLCDLYAVEKSRTTPYHPEGNGQCERFNRTLHDLLR-TLPVSRKRDWNVCLPQLLYSYNTTPHHSTGESPFFLMFGQEPRLPVDFLLGRVQEPVEGTVQEWVQEHKARLKLAFEGTREKLLAAADRRKRGHD 1176          

Query: 1296 LEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKI-VTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKGA--MVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKL----------EWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKG---YCITRKELLAVYYFCIH-FKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKG----------------------------------------------------INHQNADMVSRTKCDTCV---------QCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGIV---------EEVRKKTMIPENELQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGK--KISREKWYGSKEIPIKEELEE-----QTRRKF---NVGEEVLVKVETRHKGQD 3656
            L  L   E  K++ ++     VF   + D+G T L+ H+I +    P+  +  R P +     +E I NL ++ +IR+ +SP+ +P++ + KK+   +RLC+D+RQLN+ T + AFP+P I+E LD L G+ +FS++DL + Y+QV + E  + KTAF T  G + +NRMPFG+  AP TFQ +M ++ G+ +G   ++YLDDI+++SS+ E+H   L  VL+ ++  GL++   KC   + ++ +LGH+IS +GV TDP K++A+ N+  P  V +LRSF+G  +YYRRF+  +AK A  L +L +     K+           W+E     FE LK  LTT P+L + D  + FIL+ DAS   +GAVLSQ +++GK R IAY S  +   E+    Y   R E LA+ +     F+ YL G++  + TD+  ++++ T K  + +  Q W   L++ D+ + YR G                                                     +H  +DM S    D  +         Q + + EE ++  + +  L  +R+  R   Q G++          E   + ++P +  +E +  +H+   H GV++  D ++ R     + +++ E    CE CQ  K      + P+    + +  EI+ +D    L  T    + +L I D +SKY +  A   Q   T+ + ++ +W  +FG P  I  D G++FES ++++   +  ++   ++PYH + NGQ ER  RT+ DL+  TL   +K DW   LP++ ++ N T   +TG+SP  ++FG+  ++  +   G  + P++  ++E     + R K       E++L   + R +G D
Sbjct:  301 LSALSAGEQEKVRTLLGKYLTVFSLHEGDLGCTSLITHEIPLVDDAPVRQRYRRIPPSDYVAAKEHINNLLQSQVIRESSSPFASPIVLIRKKDG-GLRLCVDYRQLNSRTRKDAFPLPRIEESLDALSGARWFSTLDLASGYHQVAVAEADRPKTAFCTPFGLFEWNRMPFGLCNAPSTFQRLMQRMFGEQQGQSLLLYLDDIIVFSSTIEQHLERLELVLERLQLEGLKVKLAKCAFFQHQVHYLGHVISDQGVSTDPGKVEAVANWEPPTTVFQLRSFIGFASYYRRFVEGFAKLAAPLHRLVAELEGNKVRKKSARGLTNHWTEECQRSFEALKAKLTTTPVLAYADFSRPFILEVDASNGGLGAVLSQ-EQEGKVRPIAYASRGLRPTERNPVNYSSMRLEFLALKWAVAEKFREYLLGQKCIVYTDNNPLSYLSTAK--LGAMEQRWAAQLAAFDLEIRYRSGRSNRNADALSRQHFPDMQAWRDVLPGSCLPMSLQQVQQTETVGTTQATMVALPHHSPSDMASLQGADPVLKEFLPFWERQTRPSPEERRQ--LSSPTLALLRQWNRLVEQGGVLYRRVFRDDGGEAVLQILLPGSIREEVLTAVHQQHGHQGVDRTLDLLRQRCYWPGMSAEVAEWCSQCERCQVAKVTRPAARAPMGHLLASKPNEILAMDFSV-LEPTTSGIENVLVITDIFSKYTMAVATRDQRAATVAQVLVTEWFSKFGVPARIHSDQGRSFESALIQQLCDLYAVEKSRTTPYHPEGNGQCERFNRTLHDLLR-TLPVSRKRDWNVCLPQLLYSYNTTPHHSTGESPFFLMFGQEPRLPVDFLLGRVQEPVEGTVQEWVQEHKARLKLAFEGTREKLLAAADRRKRGHD 1176          

Query: 1296 LEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKI-VTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLG--KIKGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCS----------GPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEK---GYCITRKELLAVYYFCIH-FKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTC--------------------VQCQMAH---------------EEAKKGKIKTRLLDSI-------------REEGRSNIQHGIVEE----------VRKKTMIPENE------------LQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGK--KISREKWYGSKEIPIK-------EELEEQTRRKFNVGEEVLVKVETRHK-GQDRY--EGPYKVIEKVHDRRYILRN 3719
            LE L   +  K + ++    NVF A + D+G T L+ H+I +    P+  +  R P +    +++ I  L  +G+IR+ NSP+ +P++   KK+   +R+C+D+RQLN+ T R AFP+P IDE LD L G+ +F+++DL + Y QV + E  + KTAF    G + +NRMPFG+  APGTFQ +M ++ G  + +  ++YLDDI+++SS+ ++H   L  VL  +++  LR+   KC   ++E+R+LGH+IS +GV TDP KI+A+  +  P+ V +LR+FLG  +YYRRF+  +A+ A  L +L              S+ +  W+      F+ LK  LT+AP+L + D    FIL+ DAS + +GAVLSQ ++ G  R IAY S  + + E+    Y   + E LA+ +     F+ YL G    + TD+  ++++ T K  + +  Q W+  L++ D  ++YR G  ++NAD +SR    +                     VQ  +AH                E +  ++   +L S+               EG S +   ++ +          V ++ ++P++             + E ++++H+   H G+E+    ++ R     +   +    ++CE CQ  K  + +   P+    +    E++ +D    L  ++   + +L + D +SKY V      Q   T+ K ++ +W  +FG P  +  D G++FES ++++   +  I+   ++PYH   NGQ ER  RT+ +L+ A    RK+ DW   LP+V F  N T  +TTG+SP  ++FG+  ++  +   G  + P+        EE + + R  F+V ++ L +   R K   D++  E P    + V  R Y +R 
Sbjct:  267 LETLPAEDRGKAQALLQKYANVFAAHEGDLGCTTLMTHEIPLLDDAPVRQRHRRIPPSEYEAVKDHINQLLASGVIRESNSPYASPIVLARKKDGS-LRMCVDYRQLNSKTRRDAFPLPRIDESLDALSGARWFTTLDLASGYNQVPVTEGDRAKTAFCIPFGLFEWNRMPFGLCNAPGTFQRLMQRIFGDQQCQSVLLYLDDIVVFSSTIDEHLERLELVLGRLQQEKLRVKLPKCAFFQQEVRYLGHVISDQGVSTDPHKIEAVAGWQPPSTVSELRTFLGFASYYRRFVEGFARLAAPLHRLVGELDGTKSRRRKASSLQGHWTTECQQNFDALKQKLTSAPVLAYADFTLPFILEVDASHNGLGAVLSQ-EQGGSVRPIAYASRGLKATERNMQNYSSMKLEFLALKWAMTEKFREYLLGHHCVVFTDNNPLSYLSTAK--LGAMEQRWVAQLAAFDYEIKYRSGRVNRNADALSRHPNHSSAEVGNMAPGSSLPRDLQQVQVQPVLAHCEMEQLMPVFPQRTTAEVQDLQVSDPVLASVLPFWRDQRYPNYSEREGLSKVALTLLRQWKNLAEVDGLVYRRVLMPDSGQEVFQLLLPEILIPEVLEQVHQHHGHQGIERTLALLRARCYWPGMSKDVAHWCQACERCQLAKDNSRSHSAPLGHLIASRPNELVAMDFTI-LEPSRTGVENVLVLTDVFSKYTVAIPTRDQRAATVAKVLVAEWFSKFGVPARLHSDQGRSFESQLIQQLCGLYGIEKSRTTPYHPAGNGQCERFNRTLHNLLRALPVTRKR-DWHSCLPQVTFCYNTTPHQTTGESPFFLMFGQQPRLPIDFMLGQVKEPVNGTIHEWVEEHQARLRVAFDVAKDRLAEAAARRKRNHDKHVQEAPLDEGQLVLLRDYSVRG 1167          

Query: 1296 LEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKI-VTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLG--KIKGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCS----------GPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEK---GYCITRKELLAVYYFCIH-FKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTC--------------------VQCQMAH---------------EEAKKGKIKTRLLDSI-------------REEGRSNIQHGIVEE----------VRKKTMIPENE------------LQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGK--KISREKWYGSKEIPIK-------EELEEQTRRKFNVGEEVLVKVETRHK-GQDRY--EGPYKVIEKVHDRRYILRN 3719
            LE L   +  K + ++    NVF A + D+G T L+ H+I +    P+  +  R P +    +++ I  L  +G+IR+ NSP+ +P++   KK+   +R+C+D+RQLN+ T R AFP+P IDE LD L G+ +F+++DL + Y QV + E  + KTAF T  G + +NRMPFG+  APGTFQ +M ++ G  + +  ++YLDDI+++SS+ ++H   L  VL  +++  LR+   KC   ++E+R+LGH+IS +GV TDP KI+A+  +  P+ V +LR+FLG  +YYRRF+  +A+ A  L +L              S+ +  W+      F+ LK  LT+AP+L + D    FIL+ DAS + +GAVLSQ ++ G  R IAY S  + + E+    Y   + E LA+ +     F+ YL G    + TD+  ++++ T K  + +  Q W+  L++ D  ++YR G  ++NAD +SR    +                     VQ  +AH                E +  ++   +L S+               EG S +   ++ +          V ++ ++P++             + E ++++H+   H G+E+    ++ R     +   +    ++CE CQ  K  + +   P+    +    E++ +D    L  ++   + +L + D +SKY V      Q   T+ K ++ +W  +FG P  +  D G++FES ++++   +  I+   ++PYH   NGQ ER  RT+ +L+ A    RK+ DW   LP+V F  N T  +TTG+SP  ++FG+  ++  +   G  + P+        EE + + R  F+V ++ L +   R K   D++  E P    + V  R Y +R 
Sbjct:  267 LETLPAEDRGKARALLQKYANVFAAHEGDLGCTTLMTHEIPLLDDAPVRQRHRRIPPSEYEAVKDHINQLLASGVIRESNSPYASPIVLARKKDGS-LRMCVDYRQLNSKTRRDAFPLPPIDESLDALSGARWFTTLDLASGYNQVPVTEGDRAKTAFCTPFGLFEWNRMPFGLCNAPGTFQRLMQRIFGDQQCQSVLLYLDDIVVFSSTIDEHLERL--VLGRLQQEKLRVKLPKCAFFQQEVRYLGHVISDQGVSTDPHKIEAVAGWQPPSTVSELRTFLGFASYYRRFVEGFARLAAPLHRLVGELDGTKSRRRKASSLQGHWTTECQQNFDALKQKLTSAPVLAYADFTLPFILEVDASHNGLGAVLSQ-EQGGSVRPIAYASRGLKATERNMQNYSSMKLEFLALKWAMTEKFREYLLGHHCVVFTDNNPLSYLSTAK--LGAMEQRWVAQLAAFDYEIKYRSGRVNRNADALSRHPNHSSAEVGNMAPGSSLPRDLQQVQVQPVLAHCEMEQLMPVFPQRTTAEVQDLQVSDPVLASVLPFWRDKRYPNYSEREGLSKVALTLLRQWKNLAEVDGLVYRRVLMPDSGQEVFQLLLPEILIPEVLEQVHQHHGHQGIERTLALLRARCYWPGMSKDVAHWCQACERCQLAKDNSRSHSAPLGHLIASRPNELVAMDFTI-LEPSRTGVENVLVLTDVFSKYTVAIPTRDQRAATVAKVLVAEWFSKFGVPARLHSDQGRSFESQLIQQLRGLYGIEKSRTTPYHPAGNGQCERFNRTLHNLLRALPVTRKR-DWHSCLPQVTFCYNTTPHQTTGESPFFLMFGQQPRLPIDFMLGQVKEPVNGTIHEWVEEHQARLRVAFDVAKDRLAEAAARRKRNHDKHVQEAPLDEGQLVLLRDYSVRG 1165          

Query:  771 RVSEKVYRFLKR-------EMFEEEVER-IGTIETEQVVEILYNRMQGRPSITVRMNGENFDCLLDTGARINVMSVNCFNKLRGQQLTKSDDKLRCANESTIETIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGGIELQETFGFRLLKIKDIEASEKDKNYICNIEAKFGRKIKDEERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQHGI--VEEVRK---------------------KTMIPENELQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRKKTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKISREKWYGSKEIPIKEELEE------------QTRRKFNVGEEVLVKVETRHKGQDRYEGPYKVIEKVHDRRYILRNEDGKRIERNVEKLKNFLRRG 3779
            R  EK+Y+FLK+       E+ E+  E+ I ++E ++   I YN MQGRPS T+ + G   DCLLDTGARINVM+ +  ++L   ++ ++ + LRCAN S +ET+GK  + V +G++ + V FI+ + + P++IGG+ELQ  FG  L  I  +E  EK  ++IC IEA+FGR I DEERL  A++ LK+  + +L EI   + NVFMADKWD+G T+L+KHKI+T+GEPI IKP RQP+NLE KIEEAI+NL  NGIIRKCNSPWNTPL+CVWKKEKKDIRLCLDFRQLN +TERQAFPMPN+DE+LD+L GS +FSSIDLGNAYYQV+L++ESQEKTAFSTK GQ+CFNRMPFGIAAAPGTFQE+MTKVL  +   G MVYLDDILI++ ++E HY I G+VL  I  AGLR+NPEKCQI ++E++FLGHII+K+G+QTD +KI+AIQ+F KP CVK LRSFLGICNYYRRFI DYAKKAR LE +C G +N+K+ W+E     F  +K AL TAP+L FPD +KEFILDTDASFDTIGAVLSQ+D+ G E VIAYGSH+M+SHEKGYCITRKELLA+YYFC HF HYLYG+RF LRTDHKAITFM+TTKKPIT+QFQTWINYLSSLDI++EYRKG +H NADM+SR  C TCVQC M HE+AK GKIKTR+L    E G +  Q+    V+E++                      K  IP +  Q  IKE+H LLCHAG +K+  Y+++    ++L +++++++ +CE CQK K +T  TKE  +   S E FE I++DICGPL ET  +KKYI GIID YSKY  LTAI KQDE TI +T+L KWIL+FG PKE+ VDCGK FE+  ++E  K   I+L FSSPYHH TNG IERQFRTIR+ INA+L +  + +WA+I+PE+++TLNAT QKTTG SPAEI+FG+KI R KWY +KEI  +E++E+            +T R F + + VL+K E R+K   R+EGPYKVI+K+H+R Y+L++++GK + RNVEK+K+F + G
Sbjct: 2501 RTIEKIYKFLKKNGDVCINEIVEDTREQNILSVEEQKSPAITYNIMQGRPSTTLDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLRCANNSRLETMGKLNINVKMGSMERNVTFIIVKNLIPEIIGGVELQRLFGIELKCI--LEEHEKRSDFICEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEILDILHGSRYFSSIDLGNAYYQVKLDKESQEKTAFSTKEGQFCFNRMPFGIAAAPGTFQELMTKVLKDLWKDGVMVYLDDILIFTKTEEDHYNIFGKVLGKIATAGLRLNPEKCQIFRKEVKFLGHIINKDGIQTDNTKIEAIQSFQKPKCVKNLRSFLGICNYYRRFIKDYAKKARALESIC-GKNNEKIRWTEMCEKAFGEMKEALITAPVLVFPDFRKEFILDTDASFDTIGAVLSQKDEKGHEHVIAYGSHAMSSHEKGYCITRKELLAIYYFCKHFNHYLYGKRFVLRTDHKAITFMVTTKKPITAQFQTWINYLSSLDIKMEYRKGTSHTNADMLSRKTCGTCVQCMMEHEDAKTGKIKTRILTVTAEGGYNKWQNDNMEVQEIKNKLENKDCKFIMENNTVLTKQGKIWIPSDNRQRMIKEVHVLLCHAGAQKVTKYIQNNCDMENLATEVKKVIENCERCQKMKTITTKTKEETQTIKSTEPFEKIYMDICGPLKETFNKKKYICGIIDHYSKYISLTAINKQDERTISETLLNKWILKFGAPKELHVDCGKNFEARSIKELAKTAGIELIFSSPYHHNTNGIIERQFRTIREYINASLNEGGRKNWADIVPEIKYTLNATVQKTTGVSPAEIIFGRKIDRMKWYSNKEIN-REDMEKRIEDKTLKPKISKTVRNFEMEDVVLIKQEIRNKDDARWEGPYKVIKKIHERSYLLKDQNGKMVVRNVEKIKHFKKGG 3544          

Query:   91 KEVEKEVILRKIKSTEEIKETLTLMDKVEKQREQINSMKSYARVVYQEPQGRVQYKKKEQREESIRREMPECWLCHKIGHTKIDCPIKGKIECWTCHRSGHISRNCPDKKAPRCFGCGKEGHIRRLCQEIRCERCSRNGHRSEECYTKM---RYGQATERQRFTGNRYSR 591
            +EV KE+ ++ +K+ E+IKET+  ++KV K  EQ+N+++S      +   G   Y+   Q   + +RE+ E W        K +  +K  IECWTC + GH SR C  K+  +C+ CG EGHIRR C  I+C RC+  GH+  ECYT M     G+  ++++ +G R  R
Sbjct: 2245 QEVRKEIEMKDLKTAEQIKETIKKIEKVNKVIEQVNTVRSI-----RPTTGGRTYRDVVQVGAT-KREINE-W--------KPETRVK-MIECWTCQKPGHSSRECNIKRRFQCYACGVEGHIRRECPTIKCHRCNARGHKERECYTNMERRNQGRDRDQRKMSGGRIQR 2398          

Query:  864 EILYNRMQGRPSITVRMNGENFDCLLDTGARINVMSVNCFNKLRGQQLTKSDDKLR--CANESTIETIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGGIELQETFGFRLLKIKDIEASEKDKNYICNIEAKFGRKIKDEERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNIQ--------------------HGIVEEVRKKTM-----------------------------IPENELQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNG 3356
            ++++ +   R    + +NG + + L ++GA I+VMS  C+  +    L  S   L    +NE   + +G  K+        +E+  I+  K+ P+ IGG++  + FG  L ++ +IE+S  +K +             D +RL   L  LK++++S+L  +I+   N+FMA ++D+G T ++ H++ T G PI   P  QP++LE+K+EE +QNL E G++RKC SPWNTPL+ V K +   +R+CLDFR LN+VTE+ +FPMP++  +LD LG S  F SIDLG AYY VEL E SQ KTAFSTK GQ+CFNR+PFG++ AP TFQ++M ++L  +  KG +VYLDDILIY  ++E H  +L EV   I ++GL++NPEKC   K  + F+GH +S++G+QT+  KI  I+N  +P    +LRSFLG+  YYRRFI +Y+  A  L    +G  +K + W+E     F  LK  L  APIL +P   + FI+DTD SF+ IG                     +T HE GYC+TRKELL ++ F +HF+ YLYGRRF  RTDHKA+TFM TTKKPI+ QFQTW+   S  D  ++YRKG  H NA   SR     C   QM H++AKK K +TR ++S+  +G SNI                     +G    +  KT+                             +P++ ++  +   H  LCH G+ K   Y+KD +    +   I E +  C+IC   K     TKE +  +  +   E I VDI     ETK  KKY++ IID +SK   L     QDE TI   IL  WI RFG P+ I  D  + FE  M R++ +   IK  FSSPY HQ+NG
Sbjct:  274 DVMFKKDDDRKWSIMEINGFHVEMLWNSGASISVMSEKCWRLIGSPILMDSRILLSEVFSNEDK-KPLGSVKIVAKWNKKFRELNVIIVRKIHPNFIGGVDTMKIFGMELKEVNNIESSLVNKRFT------------DSDRLKNTLLTLKLDKNSELGTLISQFSNIFMASRFDLGHTKVITHELKTSGPPILQNPRGQPMHLEAKVEELVQNLLEAGVVRKCQSPWNTPLVIVGKPDG-SVRICLDFRLLNSVTEKFSFPMPDMQLLLDCLGKSKIFYSIDLGQAYYLVELNENSQIKTAFSTKEGQFCFNRLPFGLSTAPATFQKLMHQILEGLVFKGVVVYLDDILIYGENQETHDKLLFEVFTRIRDSGLKVNPEKCAFNKSVLNFIGHTVSEKGIQTNKRKISEIENATEPKSTTELRSFLGLTTYYRRFIKNYSMIAAPLYAATTG-CDKMIVWTEECRKRFINLKKLLCEAPILEYPRADRLFIIDTDDSFEAIG--------------------HLTKHEIGYCVTRKELLVLHEFIVHFRQYLYGRRFVARTDHKALTFMNTTKKPISPQFQTWMANFSEYDFALQYRKGNEHGNAGGWSRLNNTICSHYQMEHKDAKKAKCRTRCINSL--QGSSNIMKIIKQKQNEDKVTSQIISHLNGNEAHISYKTISSSIFKYLKILQIQDNVLMINTDGKLAVVVPDSYVKSLVNYFHIELCHLGINKTLFYLKDFFFLPSMNQIITECINKCKICASRKIDQGRTKEILLPRTGERFLEQIVVDI--DYMETKESKKYMIVIIDCFSKLVSLP----QDEATILNVILNNWIYRFGRPESILTDRERIFEGSMFRDWMEKFGIKQEFSSPYQHQSNG 1114          

Query: 1233 ICNIEAKFGRKIKDEERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKIKGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYL 2615
            +CNI+AKFG+ I   ER  RA ++LK+N  + L EII N+ NVFMA+KW++G T L+KHKIVTRG  INIKP RQP++LE KIEEAIQNL++NGII+                             LN VT+RQA+PM NI E+LD   G   F+SIDLGNAYYQVELEE+S+EKTAFST  GQYCFNRMPFGIA  PGT QE+M KVLG I G +VYL+DILI++++KE++Y +L +V++ I                                    + +AI++F KP C+K L+SF GICNYYRRFI DYAKK R LE+LC G  N KL W+E     FE +K ALT +P+L +PD  ++FI+DTD+SFDTIG VLSQ+D +G E+VIAYGSH+M++HEKGYCI RKELLA+YYFC HF H+LYG+RFTLRTD KAITFM++TKKPIT+QF+TWIN+L
Sbjct:  113 MCNIDAKFGKLITGTERFDRARKELKVNY-TVLAEIIKNNQNVFMANKWEIGCTALLKHKIVTRGSLINIKPRRQPIHLEPKIEEAIQNLFKNGIIK----------------------------NLNLVTDRQAYPMQNIAEILDRFEGEKHFNSIDLGNAYYQVELEEKSKEKTAFSTTTGQYCFNRMPFGIATGPGTSQELMRKVLGNINGTVVYLNDILIFTATKEQYYAVLNDVIERI-----------------------------------GRPEAIKSFQKPECIKNLKSFPGICNYYRRFIKDYAKKTRTLEELC-GKYNVKLIWAENCEKAFEDMKKALTESPVLGYPDFTRDFIIDTDSSFDTIGDVLSQKDNNGYEKVIAYGSHAMSTHEKGYCIKRKELLAIYYFCQHFNHHLYGKRFTLRTDLKAITFMLSTKKPITAQFKTWINHL 508          

Query:  906 VRMNGENFDCLLDTGARINVMSVNCFNKLRGQQLTKSDDKLRCANESTIE---TIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGGIELQETFGFRLLKIKDIEASEKDKNYICNIEAKF-GRKIKDEERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAITFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSNI 2795
            + +NG + D L D+GA I+VMS + + +L G+ +   D ++R +   + E    +G  K+   +   +K+V F    +   +++ G                  A E     + NIE+    +K  D +RL   L  LK++++SKL  +I+   N+FMA ++D+G T ++ H+I            ++P++LE K+EE +QNL E G++RK  SPWNTPL+ V K +   IR+CLDFR LN+VTE+ +F  P++  +LD LG S  FSSIDLG AYYQVEL E SQ KTAFSTK GQ+CFNR+PFG++ AP TFQ++M ++L  +  KG +VYLD+ILIY  ++E H  +L EV   I ++GL++NPEKC   K  + F+GH                                           ++Y+  A  +    +G ++K + W+E   + F  LK  L  APIL +P   + F++DTDASF  IGAVLSQ  +D  E VIAYGS  +T HE G+C+T KELLA++ F +HF+ YLYGRRF  RTDHKA+TFM TTKKPI+ QFQTW+  LS  D  ++YRKG  H NAD  SR     C  C M +++AK+ K +TR ++S+  +G SNI
Sbjct:    1 MEINGFHVDMLWDSGASISVMS-DKYWRLIGRPILM-DSRIRLSGVFSKEDEKPLGSVKI---VAKWNKKVSFHRRSRHHENILHG------------------AKE-----VNNIESLLVNKKFTDSDRLKITLSTLKLDKNSKLGTLISKFSNIFMASRFDLGHTKVITHEI-----------KKKPMHLEGKVEELVQNLLEAGVVRKSISPWNTPLVIVGKLDG-SIRMCLDFRLLNSVTEKFSFYSPDMKLLLDCLGNSKIFSSIDLGQAYYQVELNENSQIKTAFSTKEGQFCFNRLPFGLSTAPATFQKLMHQILEGLVFKGVVVYLDEILIYGENQEIHDKLLFEVFTRIRDSGLKVNPEKCAFNKSVLNFIGH-------------------------------------------TNYSIIAAPMYVATTG-NDKMIVWTEECRNSFINLKKLLCEAPILEYPRADRLFVIDTDASFGAIGAVLSQIKEDCTEVVIAYGSRHLTKHEMGHCVTIKELLALHEFIVHFRQYLYGRRFVARTDHKALTFMNTTKKPISPQFQTWMANLSEHDFALQYRKGEEHGNADGKSRLNNTKCSHCLMENKDAKEAKCRTRYINSL--QGSSNI 550          

Query: 3237 PKEIRVDCGKAFESGMMREFTKMLEIKLCFSSPYHHQTNGQIERQFRTIRDLINATLQDRK-KTDWAEILPEVEFTLNATKQKTTGKSPAEIVFGKKISREKWYGSKEI-PIKEELEEQTRRKFNVGEEVLVKVETRHKGQD 3656
            P+ I  D G  FE  M R++ +   IK  FSSPY HQ+N   ER  RT+RD++  +L + K K +W  +LP +EF+ NAT Q +T  SP EIV+G+KI+   + G + I   +EE+E++T+         LVK  T  + +D
Sbjct:  616 PESILTDRGIIFEGSMFRDWMEKFGIKQEFSSPYQHQSNILAERIIRTVRDMLATSLAEIKTKNNWCRLLPRIEFSFNATIQNSTKFSPFEIVYGRKINL--YSGVEHIQKFREEIEDETKTN-------LVKAATTMQNRD 748          

Query:  870 LYNRMQGRPSITVRMNGENFDCLLDTGARINVMSVNCFNKLRGQQLTKSDDKLRCANESTIE---TIGKTKVQVTIGNVSKEVIFIVAEKVTPDVIGGIELQETFGFRLLKIKDIEASEKDKNYICNIEAKFGRKIKDEERLIRALEQLKINEDSKLKEIITNSGNVFMADKWDVGRTHLVKHKIVTRGEPINIKPYRQPLNLESKIEEAIQNLYENGIIRKCNSPWNTPLICVWKKEKKDIRLCLDFRQLNAVTERQAFPMPNIDEMLDLLGGSVFFSSIDLGNAYYQVELEEESQEKTAFSTKNGQYCFNRMPFGIAAAPGTFQEMMTKVLGKI--KGAMVYLDDILIYSSSKEKHYTILGEVLKAIEEAGLRINPEKCQIIKEEIRFLGHIISKEGVQTDPSKIQAIQNFGKPNCVKKLRSFLGICNYYRRFISDYAKKARMLEQLCSGPSNKKLEWSEGTNSVFEGLKLALTTAPILCFPDLKKEFILDTDASFDTIGAVLSQRDKDGKERVIAYGSHSMTSHEKGYCITRKELLAVYYFCIHFKHYLYGRRFTLRTDHKAI---TFMMTTKKPITSQFQTWINYLSSLDIRVEYRKGINHQNADMVSRTKCDTCVQCQMAHEEAKKGKIKTRLLDSIREEGRSN------------------IQHGIVEEV-------------------------------RKKTMIPENELQETIKEIHRLLCHAGVEKIADYMKDRYVGKHLWSKIQEIVRSCEICQKTKALTITTKEPVKRQDSKEMFEIIFVDICGPLAETKGRKKYILGIIDQYSKYQVLTAITKQDEETIKKTILEKWILRFGCPKEIRVD 3257
            ++ +   R    + +NG + + L D+GA I+VMS  C+ +L G  +   D ++R +   + E     G  K+        +E   I+  K+ PD IGG++  + F  +L ++  IE+S  +K +             D +RL   L  LK++++SKL  +I+   N+FMA K+D+G                                  I+NL   G++RKC S WNTPL+ V K +    R+CLDFR LN+VTE+ +FPMP++  +LD LG S   SSIDL   YYQVEL E SQ KTAFSTK GQ+CFNR+PFG++ AP TFQ++M ++L  +  K  +VYLDDIL Y+ ++E H  +L EV   I ++GL+++P KC   K  + F+ H +S++G+QT+  K   I N  +     +LRSFLG+ NYYRRFI +Y+  A  L    +G ++K + W+E                                        AVLSQ  +DG E VIAY S  +T+HE GYC+ RKELL +Y   +HF+ YL   +   +   + I    +   T KP  S                   KG  H N+D +SR     C  CQ+  +++K+GK +TR ++S+   G SN                  I H I  E                                +   ++P++ ++  +   +    + G++K    +K  +    +   I E +  C+IC   K      KE +  +  +   E I VDI     ETK  KKY++ IID++SK   L+A   QDE TI   IL  WI RFG P+ I  D
Sbjct:   36 MFKKDDDRKWSMMEINGFHLEMLWDSGASISVMSEKCW-RLIGSPILM-DSRIRLSGVFSKEYEKPFGSVKIVAKRNKKVREFNVIIVRKIHPDFIGGVDTMKIFCMKLKEVNIIESSLVNKRF------------TDSDRLKNTLLTLKLDKNSKLGTLISQFSNIFMASKFDLGH---------------------------------IKNLLVAGVVRKCQSSWNTPLVIVGKPDGSS-RMCLDFRCLNSVTEKVSFPMPDMQLLLDCLGKSKILSSIDLRQVYYQVELNENSQIKTAFSTKEGQFCFNRLPFGLSTAPATFQKLMHQILEGLVFKRVVVYLDDILKYAENQETHDKLLFEVFTRIIDSGLKVSPAKCAFNKSLLNFINHTVSEKGIQTNKGKFSEIVNPIETKSTTELRSFLGLTNYYRRFIKNYSMIAAPLYAATTG-NDKMIVWTEEC--------------------------------------AVLSQIKEDGTEGVIAYVSRHLTNHEMGYCVIRKELLVLYELIVHFRQYL--DKICSQNGSQGIEIYEYNKETNKPTISDI-----------------KGEEHGNSDGISRLNNTICSHCQIEQKDSKEGKCRTRYINSL--HGSSNIMKIIKQKQNEDRVTSEIISHFIGNEAHISYETISSSIFKYLKILQIQDDVLMINSDGKLAVVVPDSYVKSLVNYFYIEQGYLGIKKTLFCLKGFFFWPSMNQIITECINKCKICASRKIDQGRRKEILFPRTGERFLEQIIVDI--AYMETKESKKYMIVIIDRFSKLISLSAAITQDEATILNVILNNWIYRFGRPESILTD 778