Kelch-like ECH-associated protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30023314 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Kelch-like ECH-associated protein vs. Ensembl Human
Match: KEAP1 (kelch like ECH associated protein 1 [Source:HGNC Symbol;Acc:HGNC:23177]) HSP 1 Score: 528.48 bits (1360), Expect = 2.328e-179 Identity = 261/568 (45.95%), Postives = 356/568 (62.68%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKIN-SPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V + P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E+ + +EF +L CQL+ I RD+LNVR E EVF++ I W +D R Y+ +L VR H + P+F++ Q++ C+ L + + L + E+L HK P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CAPMS+PR+R+ VG++D IYAVGGS +HHNS E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + ++N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++G+I+V GGYDG+ FL SVE YD T+TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREYIYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDCEQRRFYVQALLRAVRCHSLTPNFLQMQLQKCEILQSDSRCKDYLVKIFEELTLHKPTQVMPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEP 612
BLAST of Kelch-like ECH-associated protein vs. Ensembl Human
Match: KEAP1 (kelch like ECH associated protein 1 [Source:HGNC Symbol;Acc:HGNC:23177]) HSP 1 Score: 528.48 bits (1360), Expect = 2.328e-179 Identity = 261/568 (45.95%), Postives = 356/568 (62.68%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKIN-SPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V + P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E+ + +EF +L CQL+ I RD+LNVR E EVF++ I W +D R Y+ +L VR H + P+F++ Q++ C+ L + + L + E+L HK P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CAPMS+PR+R+ VG++D IYAVGGS +HHNS E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + ++N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++G+I+V GGYDG+ FL SVE YD T+TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREYIYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDCEQRRFYVQALLRAVRCHSLTPNFLQMQLQKCEILQSDSRCKDYLVKIFEELTLHKPTQVMPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEP 612
BLAST of Kelch-like ECH-associated protein vs. Ensembl Human
Match: KLHL20 (kelch like family member 20 [Source:HGNC Symbol;Acc:HGNC:25056]) HSP 1 Score: 365.925 bits (938), Expect = 1.680e-116 Identity = 201/565 (35.58%), Postives = 298/565 (52.74%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKI-----NSPHRTAGFNQVLYSAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
Y DK+ R+ + + L L D+ L VG + H+V+L+ S YFRAMFT + E E+ I I + LI F YT +I + E NV LL AA +LQ+ + EACCEFL++Q PSN +GI FA ++ C++L A +F NF E+ +EF+ L QL++ I DELNVRSE +VFN+V+ W + R L ++L HVRL + P F+ + + + ++ R ++ LL Q + + P + +VL++ GG+ ++++ E Y P T +WR ++ + R G+ + +Y +GG + S N V+ YDP+TN W + AP S R V V ++ +YAVGG +S N E++DP +WT VASM+ R+G+ VA + LYAVGG DG + L +VERYNP E+ W +A + R G IYA+GG D +L S ERY+P NQW V M RS +G V G++ GG+DG +L ++EV+D NTW M+ + G V
Sbjct: 45 YISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLN----SVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCL---------NIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGV 596 HSP 2 Score: 73.1738 bits (178), Expect = 1.016e-12 Identity = 54/190 (28.42%), Postives = 76/190 (40.00%), Query Frame = 1
Query: 1330 LYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGG--------------------SATLSTQSAHPSV------------------MHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVN 1782
LY+ GG S L E Y P KW R++ + T R G+A + G +Y +GG + + N V+ Y+PQ N W T APM R + + D+IYAVGG S ++ S V + + E FDPD+ W MN R+G GV +
Sbjct: 415 LYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLN----TVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIK 600
BLAST of Kelch-like ECH-associated protein vs. Ensembl Human
Match: KLHL12 (kelch like family member 12 [Source:HGNC Symbol;Acc:HGNC:19360]) HSP 1 Score: 350.132 bits (897), Expect = 6.156e-111 Identity = 195/568 (34.33%), Postives = 299/568 (52.64%), Query Frame = 1
Query: 535 DKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQ---HKKINSPHRTA--GFNQVLYSAGGY--YRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYD---PQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGRE 2208
+ + + +NSM +L + L D+TL+V + FP H++VLA S YF AMFTS + E + I G++ + L+ F+YT + + NV ELL AA +LQ+ V +ACCEFLE Q PSN +GI +FA ++ C L + A+ F K+F E+ +++EF+ L ++ + IK DE+ V SE VF +VI W H + R L +L +VR+ + P +I I F+ + R ++ + L+ ++ P A G N+VL GG+ + + E Y P T +W L I R +A+ S+H R+Y+IGG + + V+C D + W + APM++ R + D+IY GG H S E++DP+ QW+ + M R G G+ + ++Y +GG+DG N L SVE+Y+P +W V + RSGAGV L+ HIY +GG+D L SVE Y+ + W V M PR +GATV G+++ GYDGN L+S+E YD ++W +T M + V + RE
Sbjct: 13 NTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLS----SVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGG---------FDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLRE 567
BLAST of Kelch-like ECH-associated protein vs. Ensembl Human
Match: KLHL5 (kelch like family member 5 [Source:HGNC Symbol;Acc:HGNC:6356]) HSP 1 Score: 347.051 bits (889), Expect = 8.574e-110 Identity = 193/574 (33.62%), Postives = 307/574 (53.48%), Query Frame = 1
Query: 508 SDTFQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKK--INSPHRTAGFNQV--LYSAGGYYRHSLAT-FECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDS-ACQLRS-----VERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVL 2196
SD F +Q + + M +L D+ L G P H++VL+ S YF AMFT+ +RE EI + G+ P + LI + YTG + + E N+ LL+ A +LQ+ VVEACC+FL KQ HPSN +GI FA + GC L + A + ++F E+ R EF+ L ++ + + D++N+ +E + N+++ W HD R L ++L+++RL + P F+ N F + + + +E++ LL ++ + SP + V L++ GG AT E Y T W ++++ R + ++Y++GGR+ + N V+CY+P+T +W PMS RH + V +++ +YAVGG H + N+ E++DP + QW VA+M+ R +GVA ++ LYAVGG DG + L SVE ++P + W A +++ R G GV + +YAIGG+D+ A L S VERYDP + W VA M R A+G + K++ GGYDG +L +VE YD TN WT++ + G++G V+
Sbjct: 6 SDEF--FQALNHAEQTFKKMENYLRHKQLCDVILVAGDRRIPAHRLVLSSVSDYFAAMFTNDVREARQEEIKMEGVEPNSLWSLIQYAYTGRLELKEDNIECLLSTACLLQLSQVVEACCKFLMKQLHPSNCLGIRSFADAQGCTDLHKVAHNYTMEHFMEVIRNQEFVLLPASEIAKLLASDDMNIPNEETILNALLTWVRHDLEQRRKDLSKLLAYIRLPLLAPQFLADMENNVLFRDDIECQKLIMEAMKYHLLPERRPMLQSPRTKPRKSTVGTLFAVGGMDSTKGATSIEKYDLRTNMWTPVANMNGRRLQFGVAVLDDKLYVVGGRDGLKTLN----TVECYNPKTKTWSVMPPMSTHRHGLGVAVLEGPMYAVGG---------HDGWSYLNTVERWDPQARQWNFVATMSTPRSTVGVAVLSGKLYAVGGRDGSSCLKSVECFDPHTNKWTLCAQMSKRRGGVGVTTWNGLLYAIGGHDAPASNLTSRLSDCVERYDPKTDMWTAVASMSISRDAVGVCLLGDKLYAVGGYDGQAYLNTVEAYDPQTNEWTQVAPLCLGRAGACVV 564 HSP 2 Score: 126.716 bits (317), Expect = 7.134e-30 Identity = 73/199 (36.68%), Postives = 109/199 (54.77%), Query Frame = 1
Query: 1330 LYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGG-SATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVAL 1920
+Y+ GG+ S L T E + P +W ++ + T RS + + G++Y +GGR+ S V+C+DP TN W CA MS R V V + ++YA+GG A S ++ S + E++DP + WT VASM+ R +GV + LYAVGG+DG+ L +VE Y+P + W VA L R+GA VV +
Sbjct: 376 MYAVGGHDGWSYLNTVERWDPQARQWNFVATMSTPRSTVGVAVLSGKLYAVGGRDGSSCLK----SVECFDPHTNKWTLCAQMSKRRGGVGVTTWNGLLYAIGGHDAPASNLTSRLS----DCVERYDPKTDMWTAVASMSISRDAVGVCLLGDKLYAVGGYDGQAYLNTVEAYDPQTNEWTQVAPLCLGRAGACVVTV 566 HSP 3 Score: 67.781 bits (164), Expect = 4.034e-11 Identity = 35/96 (36.46%), Postives = 50/96 (52.08%), Query Frame = 1
Query: 1930 IYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQF 2217
++A+GG DS S+E+YD N W VA M R G V + K++V GG DG + L +VE Y+ T TW+ M M + G V + P +
Sbjct: 282 LFAVGGMDSTKGATSIEKYDLRTNMWTPVANMNGRRLQFGVAVLDDKLYVVGGRDGLKTLNTVECYNPKTKTWSVMPPMSTHRHGLGVAVLEGPMY 377
BLAST of Kelch-like ECH-associated protein vs. Ensembl Celegans
Match: kel-20 (KELch-repeat containing protein [Source:UniProtKB/TrEMBL;Acc:O61795]) HSP 1 Score: 335.88 bits (860), Expect = 1.705e-105 Identity = 192/536 (35.82%), Postives = 280/536 (52.24%), Query Frame = 1
Query: 592 LTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL-------QHKKINSPHRTAGFNQVLYSAGGYYR-HSLATFECYSPVTG--KWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKM 2166
L D+TL G + H+VVL+ S YF +MFTS M E M EI + I P + LI F YTG I I +SNV ++L AA +LQ+H V ACC++L+KQ PSN +GI FA ++ CK+L A F KNF+ + +EF L L IK D+LN SE VF++VI+W HD S R +L +LSHVRL P F+ S + + + +R ++ LL P + ++VLY+ GG+ ++A+ E P+ G W+ ++ + R G+ + +Y +GG + N ++ YDP TN W + AP + R V V + +YAVGG S + EK+DP +W VASM R+G+ V+ VN +YAVGG +G L +VERY+P WE V + R G D +IYA+GG D+ +L + ERY ++++W V M RS +G V K++ GG+DG +L SVE++D TN W ++M
Sbjct: 55 LCDVTLICGWKRINAHRVVLSACSPYFLSMFTSQMAECYMREINMEEIEPPTLEALIEFCYTGAIAIDDSNVQDILPAACLLQIHEVQTACCDYLKKQLDPSNCLGIRAFADTHSCKELLSSADEFALKNFSRVIGKEEFQMLTVESLTTIIKSDKLNAASEELVFSAVIQWVRHDISKRKTHLSMLLSHVRLPLCTPKFLVSVVSEEILVKSDPASRDLVDEAKNYLLLPVERPNMQGPRTKPRKPLQGSEVLYAVGGWCSGDAIASIERLDPMKGGTTWKCVAPMGKRRCGVGVAVLENLLYAVGGHDGQSYLN----SIERYDPMTNQWSSDVAPTATCRTSVGVAAFNGSLYAVGGQDGESCL---------DVVEKYDPRKNEWAKVASMGTRRLGVSVSVVNGCIYAVGGSNGPAPLNTVERYDPRVGKWEEVRPMLTKRKHLGTAVYDGYIYAVGGRDTTTELNTAERYSVERDEWQPVVAMSNRRSGVGVAVVGEKLYAVGGFDGQTYLKSVEIFDKDTNRWKTHSQM 577
BLAST of Kelch-like ECH-associated protein vs. Ensembl Celegans
Match: kel-8 (Kelch-like protein 8 [Source:UniProtKB/Swiss-Prot;Acc:G5ED84]) HSP 1 Score: 286.96 bits (733), Expect = 3.727e-86 Identity = 170/601 (28.29%), Postives = 298/601 (49.58%), Query Frame = 1
Query: 499 ELISDT---FQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPH----RTAGFNQ------------------------VLYSAGGYYRHS--LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHV---DCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
EL+S++ Y+ + + + M M L L D+ L V + H+ +LA AS YF+AMFT+GM E+ I + I + ++ +IYT +I I +NV +L+ AT+LQM +V AC +FL N + ++ F+ C L + F F I + EF S+ L + R +LNV E +VF ++++W + + R + +++ +RLH + +F+ + + ++ ++ R + +++ D + K P T+ ++ ++ AGG + ++ E Y +W + D+ + R + S +G +Y IGG + T H+ + + P W+ A M R +AV ++++IYAVGG L + + +V E++D + +W+ VA M+ R G+GVA + R L+A+GG DG + L + ER++P D W+ +AS+ R+G+GV LD ++YAIGG+D L + ERYDPD ++W+ + M PR +G GK++ GG+DG+++L +VE YD N W ++ ++G V
Sbjct: 76 ELVSNSKGSCMEYENQEQSSKIMEQMRILRQTEELCDVELLVAGSVIRAHRYILAAASPYFKAMFTNGMVEMKKLTIELQDIPEESVRIIVDYIYTDKIAITMNNVHQLIFTATVLQMDVIVVACQQFLATMITSHNCMSLYHFSDIYNCTNLISSIEDFASSQFRCIRKSPEFNSISFHHLKSLLNRSDLNVSEEQDVFETIVQWVSSNPRDRQHHFVQLFKTLRLHLVGWNFLCEAVNSNSYVKNSQECREIISAMVLDAMTPSKRKHPESNHENTSEYSASMACPSLTASSSSSTSTFRKSVAGAIFCAGGRGKAGGPFSSVEAYDWRRNQWIEVPDMMSQRRHVGVVSANGNLYAIGGHDG-------TAHLATAEAFQPSIRQWKRIASMKTARRGIAVASIENVIYAVGG---LDDTTCYKTV------ERYDIEEDEWSTVADMDVQRGGVGVAVIGRYLFAIGGNDGTSSLETCERFDPMIDKWKRIASMKNRRAGSGVCVLDGYLYAIGGFDDNAPLETCERYDPDADKWITLDKMSSPRGGVGVAALGGKVYAIGGHDGSDYLNTVECYDPIANRWQPAAEIKECRAGAGV 660 HSP 2 Score: 103.219 bits (256), Expect = 1.772e-22 Identity = 68/253 (26.88%), Postives = 121/253 (47.83%), Query Frame = 1
Query: 1321 NQVLYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGS----------------------ATLSTQSAHPSVMHHN----------------SAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSAC 1962
N LY+ GG+ + LAT E + P +W+R++ + TAR G+A S+ +Y +GG +++ Y V+ YD + + W T A M + R V V ++ ++A+GG+ A++ + A V + + E++DPD+ +W + M++ R G+GVA + +YA+GG DG + L +VE Y+P + W+ A + R+GAGV + ++ + C
Sbjct: 429 NGNLYAIGGHDGTAHLATAEAFQPSIRQWKRIASMKTARRGIAVASIENVIYAVGGLDDTTCYK----TVERYDIEEDEWSTVADMDVQRGGVGVAVIGRYLFAIGGNDGTSSLETCERFDPMIDKWKRIASMKNRRAGSGVCVLDGYLYAIGGFDDNAPLETCERYDPDADKWITLDKMSSPRGGVGVAALGGKVYAIGGHDGSDYLNTVECYDPIANRWQPAAEIKECRAGAGVAWANVRMHQLSRTPEKC 677
BLAST of Kelch-like ECH-associated protein vs. Ensembl Celegans
Match: kel-8 (Kelch-like protein 8 [Source:UniProtKB/Swiss-Prot;Acc:G5ED84]) HSP 1 Score: 287.73 bits (735), Expect = 5.624e-86 Identity = 170/601 (28.29%), Postives = 298/601 (49.58%), Query Frame = 1
Query: 499 ELISDT---FQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPH----RTAGFNQ------------------------VLYSAGGYYRHS--LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHV---DCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
EL+S++ Y+ + + + M M L L D+ L V + H+ +LA AS YF+AMFT+GM E+ I + I + ++ +IYT +I I +NV +L+ AT+LQM +V AC +FL N + ++ F+ C L + F F I + EF S+ L + R +LNV E +VF ++++W + + R + +++ +RLH + +F+ + + ++ ++ R + +++ D + K P T+ ++ ++ AGG + ++ E Y +W + D+ + R + S +G +Y IGG + T H+ + + P W+ A M R +AV ++++IYAVGG L + + +V E++D + +W+ VA M+ R G+GVA + R L+A+GG DG + L + ER++P D W+ +AS+ R+G+GV LD ++YAIGG+D L + ERYDPD ++W+ + M PR +G GK++ GG+DG+++L +VE YD N W ++ ++G V
Sbjct: 113 ELVSNSKGSCMEYENQEQSSKIMEQMRILRQTEELCDVELLVAGSVIRAHRYILAAASPYFKAMFTNGMVEMKKLTIELQDIPEESVRIIVDYIYTDKIAITMNNVHQLIFTATVLQMDVIVVACQQFLATMITSHNCMSLYHFSDIYNCTNLISSIEDFASSQFRCIRKSPEFNSISFHHLKSLLNRSDLNVSEEQDVFETIVQWVSSNPRDRQHHFVQLFKTLRLHLVGWNFLCEAVNSNSYVKNSQECREIISAMVLDAMTPSKRKHPESNHENTSEYSASMACPSLTASSSSSTSTFRKSVAGAIFCAGGRGKAGGPFSSVEAYDWRRNQWIEVPDMMSQRRHVGVVSANGNLYAIGGHDG-------TAHLATAEAFQPSIRQWKRIASMKTARRGIAVASIENVIYAVGG---LDDTTCYKTV------ERYDIEEDEWSTVADMDVQRGGVGVAVIGRYLFAIGGNDGTSSLETCERFDPMIDKWKRIASMKNRRAGSGVCVLDGYLYAIGGFDDNAPLETCERYDPDADKWITLDKMSSPRGGVGVAALGGKVYAIGGHDGSDYLNTVECYDPIANRWQPAAEIKECRAGAGV 697 HSP 2 Score: 103.219 bits (256), Expect = 2.128e-22 Identity = 68/253 (26.88%), Postives = 121/253 (47.83%), Query Frame = 1
Query: 1321 NQVLYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGS----------------------ATLSTQSAHPSVMHHN----------------SAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSAC 1962
N LY+ GG+ + LAT E + P +W+R++ + TAR G+A S+ +Y +GG +++ Y V+ YD + + W T A M + R V V ++ ++A+GG+ A++ + A V + + E++DPD+ +W + M++ R G+GVA + +YA+GG DG + L +VE Y+P + W+ A + R+GAGV + ++ + C
Sbjct: 466 NGNLYAIGGHDGTAHLATAEAFQPSIRQWKRIASMKTARRGIAVASIENVIYAVGGLDDTTCYK----TVERYDIEEDEWSTVADMDVQRGGVGVAVIGRYLFAIGGNDGTSSLETCERFDPMIDKWKRIASMKNRRAGSGVCVLDGYLYAIGGFDDNAPLETCERYDPDADKWITLDKMSSPRGGVGVAALGGKVYAIGGHDGSDYLNTVECYDPIANRWQPAAEIKECRAGAGVAWANVRMHQLSRTPEKC 714
BLAST of Kelch-like ECH-associated protein vs. Ensembl Celegans
Match: kel-1 (KELch-repeat containing protein; Kel-1 protein [Source:UniProtKB/TrEMBL;Acc:G5EGS4]) HSP 1 Score: 263.077 bits (671), Expect = 6.873e-78 Identity = 170/539 (31.54%), Postives = 274/539 (50.83%), Query Frame = 1
Query: 637 HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHK----KINS--PH--------------RTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPT--ARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENR--LGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKS 2181
H+V+L+ +S+YFRAMFT G+RE IPI + V+++LI ++YTG + I E NV +LA A++LQ+ V +AC F+ + +N +G+ EFA ++ C +LA AQ + ++F EI +E LSL E I+ D + V SE V +V+ W H+ R +L E++S+VRL + ++ + +N + + K +CL ++E + Q K I+S PH +Q + GG ++ + + P + W + +P RSG++ C +G VY GG N ++ VD YDP+T++W++ MS R + ++YAVGG + + SAE FDP +G W P+ SM+ R +GVA +YA+GGFDG ++ L +VE ++ W ++ RSGAGV D+ I A+GG+ A RS E + +W+ +A M PR AT G ++ GG DG+ L+++E + + +DA S
Sbjct: 85 HRVILSASSSYFRAMFTGGLRESTQRIIPIKEVDVEVLSQLIDYMYTGRMRIDEQNVQTILATASLLQLTCVRDACARFMLELLDMTNCVGMAEFARAHACHQLAHAAQLYTRQHFVEIIDNEELLSLDKDAFCELIQDDRITVPSEKPVMQAVLNWVAHEEPSRRPFLAELMSNVRLPLLGDDYLFEKWRNDEMI---KSDAACLNVIIEGMHQLKITKQDISSTEPHYPIQELNRKWFVAREPMPESQHIMIVGGQAPKAITNVDLFDPDSQLWSSCASLPQRRCRSGVSMC--NGYVYTTGGFNGAQRVR----SVDFYDPRTDTWRSANQMSARRSTHGITTCQQVLYAVGGFDGTTGLA---------SAEYFDPHTGNWFPLPSMSTRRSSVGVAAFEEDIYAIGGFDGVSKQCLNTVEIFDRRAHKWRPGPAMLNVRSGAGVTVYDKKIIAVGGHKGAEIHRSAEILIGE--EWIELANMAIPRRNTAATALNGLLYAVGGDDGSSNLSTIECIQLSDRSDAQWKIVDAPMS 603 HSP 2 Score: 76.6406 bits (187), Expect = 3.136e-14 Identity = 42/132 (31.82%), Postives = 65/132 (49.24%), Query Frame = 1
Query: 1798 VGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
VGG + +V+ ++PD W ASL + R +GV + ++Y GG++ A ++RSV+ YDP + W M RS G T + ++ GG+DG L S E +D T W + M +S V
Sbjct: 336 VGG-QAPKAITNVDLFDPDSQLWSSCASLPQRRCRSGVSMCNGYVYTTGGFNGAQRVRSVDFYDPRTDTWRSANQMSARRSTHGITTCQQVLYAVGGFDGTTGLASAEYFDPHTGNWFPLPSMSTRRSSVGV 466
BLAST of Kelch-like ECH-associated protein vs. Ensembl Celegans
Match: kel-3 (KELch-repeat containing protein [Source:UniProtKB/TrEMBL;Acc:O18147]) HSP 1 Score: 253.447 bits (646), Expect = 1.292e-74 Identity = 171/544 (31.43%), Postives = 256/544 (47.06%), Query Frame = 1
Query: 589 RLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCK-KLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQF 2217
+L D+ L V HKV+LA YFR MFT + E NM EI I ++ ++ L+ F YTGE+ I SNV ++ A QM VV+ C FL + HPSN + I EF + K+ E +I K+F + + ++F L +E ++ D L V SE +V+ + + W N D R +IL VRL + P ++ S + + + ++ R ++ + L P R R + +F+C +P RL I V G + IGG + + V+ YDP + W M R RV V + +YA+GG + Q + EKFD D+ +WT ++ + R L A V LY GG+DG + L S+E Y+ + + WE + RS AGV +D+HIY GG+D SVER D + QW + MI+ R GA ++GKI+V GGYDG FL SVEVYD W+ ++ M+ +S +++ E F
Sbjct: 49 QLCDVALLVENRKLSAHKVILAATIPYFRGMFTLDLMEANMKEINIEDMNYETVDALLSFAYTGELRITTSNVQSIMLGANFFQMLEVVQHCGNFLLTRLHPSNALSIREFCKMMCVEEKITEMTDDYIQKHFMAVSKDEDFKRLSLEDAIELLRNDHLYVDSEEQVYVAAMEWLNCD-VIRHEQAAKILPCVRLPLLSPTYLSSIVASNPIIKKDIPCRDLIDEAKDYHLL------PDR---------------RSLIKSFKC-TP------RLCQI-----------VPGLIVAIGGLMHQ---SQSKSSVEIYDPTSKKWSPIDGMVTLRTRVGVAVNQRQVYAIGG---FNGQD------RLDLVEKFDYDTLKWTTLSPLTRKRSALAAAFVTNRLYVCGGYDGLHSLSSIEIYDINRNVWEAGPPMENMRSAAGVTVIDKHIYICGGHDGMQIFASVERLDTENQQWERIPSMIQQRCRFGAATFKGKIYVAGGYDGTSFLKSVEVYDPVEKKWSPVSPMNMRRSRVSLVSTNEGLF 540
BLAST of Kelch-like ECH-associated protein vs. Ensembl Fly
Match: Keap1 (gene:FBgn0038475 transcript:FBtr0083424) HSP 1 Score: 529.25 bits (1362), Expect = 2.992e-178 Identity = 250/560 (44.64%), Postives = 361/560 (64.46%), Query Frame = 1
Query: 532 IDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
+ Y +E + MY + G LTD+ L+V ELFP HKVVL+ AS YF+AMFT G++E M + + G+ P ++R+++F+YTG+I + E VC+LL AATM Q+ +V++ACC FLE+Q P+N IGI FA +GC +L +KA FI++NF ++ + +EFL L QL+ I+RDELNV+ E EV+N+V++W +D R + IL VR + P+F++ Q+KNC L + R L + +DL HK RT ++++ AGG++RHSL E Y+ W L+++ RSGL A + G+ Y +GGRNN+ ++D+ VD Y T +W+ CAPMS+PRHRV V ++D+++YAVGGSA + +HN+ E +DPD +WT V M+ R+G+GV VNRLLYA+GGFDG RL SVE Y+P+ + W F+ L RSGAGV A++Q+IY +GG+D QL +VERYD + + W VAP+ RSAL T + K++ GG+DGN FL+ VEVYD TNTWT T + +G+SGHA + +P
Sbjct: 37 MSNYAKEALKMMYMMRSHGMLTDVVLEVKKELFPAHKVVLSAASPYFKAMFTGGLKESEMSRVQLQGVCPTAMSRILYFMYTGQIRVTEVTVCQLLPAATMFQVPNVIDACCAFLERQLDPTNAIGIAHFAEQHGCVELQKKANVFIERNFTQVCQEEEFLQLSAYQLIALIRRDELNVQEEREVYNAVLKWVKYDEDNRHCKMEHILGAVRCQFLTPNFLKEQMKNCDVLRKVPACREYLAKIFKDLTLHKCPGVKERTPNTTRMIFVAGGFFRHSLDILEAYNVDDMTWTTLANLRIPRSGLGAAFLKGKFYAVGGRNNNIGSSYDSDWVDRYSAVTETWRPCAPMSVPRHRVGVAVMDELMYAVGGSAGME---------YHNTVEYYDPDLDRWTLVQPMHAKRLGVGVVVVNRLLYAIGGFDGNERLASVECYHPENNEWSFLPPLQTGRSGAGVAAINQYIYVVGGFDGTRQLATVERYDTENDTWDMVAPIQIARSALSLTPLDEKLYAIGGFDGNNFLSIVEVYDPRTNTWTTGTPLKSGRSGHASAVIYQP 587
BLAST of Kelch-like ECH-associated protein vs. Ensembl Fly
Match: Keap1 (gene:FBgn0038475 transcript:FBtr0083422) HSP 1 Score: 529.25 bits (1362), Expect = 2.992e-178 Identity = 250/560 (44.64%), Postives = 361/560 (64.46%), Query Frame = 1
Query: 532 IDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
+ Y +E + MY + G LTD+ L+V ELFP HKVVL+ AS YF+AMFT G++E M + + G+ P ++R+++F+YTG+I + E VC+LL AATM Q+ +V++ACC FLE+Q P+N IGI FA +GC +L +KA FI++NF ++ + +EFL L QL+ I+RDELNV+ E EV+N+V++W +D R + IL VR + P+F++ Q+KNC L + R L + +DL HK RT ++++ AGG++RHSL E Y+ W L+++ RSGL A + G+ Y +GGRNN+ ++D+ VD Y T +W+ CAPMS+PRHRV V ++D+++YAVGGSA + +HN+ E +DPD +WT V M+ R+G+GV VNRLLYA+GGFDG RL SVE Y+P+ + W F+ L RSGAGV A++Q+IY +GG+D QL +VERYD + + W VAP+ RSAL T + K++ GG+DGN FL+ VEVYD TNTWT T + +G+SGHA + +P
Sbjct: 37 MSNYAKEALKMMYMMRSHGMLTDVVLEVKKELFPAHKVVLSAASPYFKAMFTGGLKESEMSRVQLQGVCPTAMSRILYFMYTGQIRVTEVTVCQLLPAATMFQVPNVIDACCAFLERQLDPTNAIGIAHFAEQHGCVELQKKANVFIERNFTQVCQEEEFLQLSAYQLIALIRRDELNVQEEREVYNAVLKWVKYDEDNRHCKMEHILGAVRCQFLTPNFLKEQMKNCDVLRKVPACREYLAKIFKDLTLHKCPGVKERTPNTTRMIFVAGGFFRHSLDILEAYNVDDMTWTTLANLRIPRSGLGAAFLKGKFYAVGGRNNNIGSSYDSDWVDRYSAVTETWRPCAPMSVPRHRVGVAVMDELMYAVGGSAGME---------YHNTVEYYDPDLDRWTLVQPMHAKRLGVGVVVVNRLLYAIGGFDGNERLASVECYHPENNEWSFLPPLQTGRSGAGVAAINQYIYVVGGFDGTRQLATVERYDTENDTWDMVAPIQIARSALSLTPLDEKLYAIGGFDGNNFLSIVEVYDPRTNTWTTGTPLKSGRSGHASAVIYQP 587
BLAST of Kelch-like ECH-associated protein vs. Ensembl Fly
Match: Keap1 (gene:FBgn0038475 transcript:FBtr0083423) HSP 1 Score: 529.25 bits (1362), Expect = 8.360e-178 Identity = 250/560 (44.64%), Postives = 361/560 (64.46%), Query Frame = 1
Query: 532 IDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
+ Y +E + MY + G LTD+ L+V ELFP HKVVL+ AS YF+AMFT G++E M + + G+ P ++R+++F+YTG+I + E VC+LL AATM Q+ +V++ACC FLE+Q P+N IGI FA +GC +L +KA FI++NF ++ + +EFL L QL+ I+RDELNV+ E EV+N+V++W +D R + IL VR + P+F++ Q+KNC L + R L + +DL HK RT ++++ AGG++RHSL E Y+ W L+++ RSGL A + G+ Y +GGRNN+ ++D+ VD Y T +W+ CAPMS+PRHRV V ++D+++YAVGGSA + +HN+ E +DPD +WT V M+ R+G+GV VNRLLYA+GGFDG RL SVE Y+P+ + W F+ L RSGAGV A++Q+IY +GG+D QL +VERYD + + W VAP+ RSAL T + K++ GG+DGN FL+ VEVYD TNTWT T + +G+SGHA + +P
Sbjct: 69 MSNYAKEALKMMYMMRSHGMLTDVVLEVKKELFPAHKVVLSAASPYFKAMFTGGLKESEMSRVQLQGVCPTAMSRILYFMYTGQIRVTEVTVCQLLPAATMFQVPNVIDACCAFLERQLDPTNAIGIAHFAEQHGCVELQKKANVFIERNFTQVCQEEEFLQLSAYQLIALIRRDELNVQEEREVYNAVLKWVKYDEDNRHCKMEHILGAVRCQFLTPNFLKEQMKNCDVLRKVPACREYLAKIFKDLTLHKCPGVKERTPNTTRMIFVAGGFFRHSLDILEAYNVDDMTWTTLANLRIPRSGLGAAFLKGKFYAVGGRNNNIGSSYDSDWVDRYSAVTETWRPCAPMSVPRHRVGVAVMDELMYAVGGSAGME---------YHNTVEYYDPDLDRWTLVQPMHAKRLGVGVVVVNRLLYAIGGFDGNERLASVECYHPENNEWSFLPPLQTGRSGAGVAAINQYIYVVGGFDGTRQLATVERYDTENDTWDMVAPIQIARSALSLTPLDEKLYAIGGFDGNNFLSIVEVYDPRTNTWTTGTPLKSGRSGHASAVIYQP 619
BLAST of Kelch-like ECH-associated protein vs. Ensembl Fly
Match: dbo (gene:FBgn0040230 transcript:FBtr0332133) HSP 1 Score: 349.747 bits (896), Expect = 1.958e-110 Identity = 193/576 (33.51%), Postives = 306/576 (53.12%), Query Frame = 1
Query: 535 DKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKI-----NSPHRTAGFNQVLYSAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQFED*LFI 2235
+K+ + + + L L D+ L VG H+V+L+ S+YF AMFT + E E+ I I + LI F YT I++ ESNV LL AA +LQ+ + + CCEFL++Q P+N +GI FA ++ C++L A +F NF E+ +EFL L QL++ I DELNVRSE +VFN+V+ W ++ + R +L ++L HVRL + P F+ + + + ++ R ++ LL Q + + P + +VL++ GG+ ++A+ E + P T W+ ++ + R G+ ++ +Y +GG + N ++ YDPQTN W AP + R V V ++D +YAVGG V N E++DP +W+ VA M R+G+ VA + LYA+GG DG+ L +VERY+P + W V+ ++ R G + +IYA+GG D +L S ERY+P N W + M RS +G V G+++ GG+DG+ +L ++EVYD TN W M+ + G V + R PQ E+ ++I
Sbjct: 52 EKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLN----SIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGG---------QDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAPQTENYMWI 614
BLAST of Kelch-like ECH-associated protein vs. Ensembl Fly
Match: KLHL18 (gene:FBgn0037978 transcript:FBtr0082556) HSP 1 Score: 347.436 bits (890), Expect = 4.147e-110 Identity = 199/571 (34.85%), Postives = 295/571 (51.66%), Query Frame = 1
Query: 505 ISDTFQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIH--GISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKINSPHRTAG-----FNQVLYSAGGYYR--HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSG 2184
+ D + Y+ DK E + G+L D+TLKV + F H+VVLA YF AMFT+ M E + EI + I P + LI+++Y+G++ I NV L+ A+ LQ+ +V +AC FL +FHP NV+GI FA S C++L + A ++ID+NF ++ + +EFL+L QL+E ++RDELNVR+E +F + ++W + R+ ++L+ VRL + P F+ ++ + + + R L+ + L + + + RT F +Y+ GG S++T E Y P+T KW+ + RS + ++G++Y GG N +E + V+ YDP+ N W M R V V +DD IY GG + V N+ E + P S W VA M R GV +N +YA+GG DG + SVERY+ ED W ++ + R GV L+ IY GGY LRSVE YDP + W V PM RS + GK+W GGYDG L++VEVYD T+ WT M M A G
Sbjct: 9 VEDQYFVYKHDKLFGESFPLFKEIRRMGKLCDVTLKVEDQTFSAHRVVLAATIPYFYAMFTNNMAESRIKEITMKESAIEPSALESLINYVYSGQVRIDNQNVQNLMVGASFLQLSNVRDACASFLISRFHPHNVLGIRTFADSMICRQLIDAADKYIDQNFAKVSQSEEFLALDCEQLLELMRRDELNVRTEEVIFEACMKWVKYAEDKRSELFPQVLAAVRLPLLSPQFLADRVAREELIRSSHQCRDLLDEAKDFHLMPERRGLLQSFRTRQRSGEFFTGQIYAVGGLASTGESVSTVEIYDPLTKKWKMGEQMSMMRSRVGVAVLNGKLYAFGGFNGTERLS----TVEVYDPRKNKWSQGCAMLCKRSAVGVAALDDCIYVCGG---------YDGVTSLNTVEVYYPKSNTWKTVAQMMKYRSAGGVTQLNGYVYALGGHDGLSIFDSVERYDQAEDVWVKMSPMLNRRCRLGVATLNGKIYVCGGYCGNSFLRSVECYDPQTDTWKLVTPMNCKRSRVALAANMGKLWAIGGYDGESNLSTVEVYDPETDKWTFMPPMCAHSGG 566 HSP 2 Score: 95.5153 bits (236), Expect = 4.597e-20 Identity = 53/137 (38.69%), Postives = 77/137 (56.20%), Query Frame = 1
Query: 1789 LYAVGGF--DGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
+YAVGG GE+ + +VE Y+P W+ ++ RS GV L+ +YA GG++ +L +VE YDP KN+W M+ RSA+G + I+V GGYDG L +VEVY +NTW + +M +S V
Sbjct: 293 IYAVGGLASTGES-VSTVEIYDPLTKKWKMGEQMSMMRSRVGVAVLNGKLYAFGGFNGTERLSTVEVYDPRKNKWSQGCAMLCKRSAVGVAALDDCIYVCGGYDGVTSLNTVEVYYPKSNTWKTVAQMMKYRSAGGV 428 HSP 3 Score: 70.4774 bits (171), Expect = 3.521e-12 Identity = 48/165 (29.09%), Postives = 82/165 (49.70%), Query Frame = 1
Query: 1303 HRTAG----FNQVLYSAGGYYRHSL-ATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGR-NNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATV 1779
+R+AG N +Y+ GG+ S+ + E Y W ++S + R L +++G++Y+ GG NS L + V+CYDPQT++W+ PM+ R RVA+ ++A+GG S S + E +DP++ +WT + M G+G +
Sbjct: 422 YRSAGGVTQLNGYVYALGGHDGLSIFDSVERYDQAEDVWVKMSPMLNRRCRLGVATLNGKIYVCGGYCGNSFLRS-----VECYDPQTDTWKLVTPMNCKRSRVALAANMGKLWAIGGYDGESNLS---------TVEVYDPETDKWTFMPPMCAHSGGVGAGVI 572 HSP 4 Score: 69.3218 bits (168), Expect = 7.287e-12 Identity = 40/103 (38.83%), Postives = 56/103 (54.37%), Query Frame = 1
Query: 1888 RTRSGAGVVALDQHIYAIGGYDSACQ-LRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
RTR +G Q IYA+GG S + + +VE YDP +W M RS +G V GK++ FGG++G E L++VEVYD N W++ M +S V
Sbjct: 280 RTRQRSGEFFTGQ-IYAVGGLASTGESVSTVEIYDPLTKKWKMGEQMSMMRSRVGVAVLNGKLYAFGGFNGTERLSTVEVYDPRKNKWSQGCAMLCKRSAVGV 381
BLAST of Kelch-like ECH-associated protein vs. Ensembl Zebrafish
Match: keap1b (kelch-like ECH-associated protein 1b [Source:ZFIN;Acc:ZDB-GENE-080508-1]) HSP 1 Score: 525.783 bits (1353), Expect = 4.714e-179 Identity = 261/569 (45.87%), Postives = 359/569 (63.09%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKV-----GTEL-FPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + M L +L D+TL+V T + F HKVVLA +S FRAMFT+G++E M +PI GI P V+ RLI F YT I +GE V ++ A M Q+ VV+ACC+FL +Q PSN IGI FA GC +L +KA+ +I NF+++ +EF +L CQL+ I RDELNVR E EVF++ + W +DR R Y+ +L VR H + PHF++ Q+++ ++ +++K L + DL HK P RT Q++Y+ GGY+R SL+ E ++P +G W RL+D+ RSGLAAC + G +Y +GGRNN N D+ +DCY+P N W+ CA MS+PR+R+ VG++D +IYAVGGS + HHNS E++DP+ W V+ M RIG+GVA +NRLLYAVGGFDG +RL S E YNP+ D W +A++N RSGAGV AL +IY +GGYD QL +VERYD +K+ W F A M RSALG T + G+I+V GGYDGN FL SVE +D T++WTE+T M +G+SG V + EP
Sbjct: 21 YTLESHTAAAFAIMNELRRERQLCDVTLRVRYCPLDTHVDFVAHKVVLASSSPVFRAMFTNGLKECGMEVVPIEGIHPKVMGRLIEFAYTASISVGEKCVIHVMNGAVMYQIDSVVQACCDFLVEQLDPSNAIGIASFAEQIGCTELHQKAREYIYMNFSQVATQEEFFTLSHCQLVTLISRDELNVRCESEVFHACVAWVQYDREERRPYVQALLQAVRCHSLTPHFLQRQLEHFEWDAQSK---DYLSQIFRDLTLHKPTKVIPLRTPKVPQLIYTVGGYFRQSLSFLEAFNPCSGAWLRLADLQVPRSGLAACVISGLLYAVGGRNNGPDGNMDSHTLDCYNPMNNCWRPCAHMSVPRNRIGVGVIDGMIYAVGGSHGCT---------HHNSVERYDPERDSWQLVSPMLTRRIGVGVAVINRLLYAVGGFDGTHRLSSAECYNPERDEWRSIAAMNTVRSGAGVCALGNYIYVMGGYDGTNQLNTVERYDVEKDSWSFSASMRHRRSALGVTTHHGRIYVLGGYDGNTFLDSVECFDPETDSWTEVTHMKSGRSGVGVAVTMEP 577
BLAST of Kelch-like ECH-associated protein vs. Ensembl Zebrafish
Match: keap1b (kelch-like ECH-associated protein 1b [Source:ZFIN;Acc:ZDB-GENE-080508-1]) HSP 1 Score: 526.168 bits (1354), Expect = 5.000e-179 Identity = 261/569 (45.87%), Postives = 359/569 (63.09%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKV-----GTEL-FPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + M L +L D+TL+V T + F HKVVLA +S FRAMFT+G++E M +PI GI P V+ RLI F YT I +GE V ++ A M Q+ VV+ACC+FL +Q PSN IGI FA GC +L +KA+ +I NF+++ +EF +L CQL+ I RDELNVR E EVF++ + W +DR R Y+ +L VR H + PHF++ Q+++ ++ +++K L + DL HK P RT Q++Y+ GGY+R SL+ E ++P +G W RL+D+ RSGLAAC + G +Y +GGRNN N D+ +DCY+P N W+ CA MS+PR+R+ VG++D +IYAVGGS + HHNS E++DP+ W V+ M RIG+GVA +NRLLYAVGGFDG +RL S E YNP+ D W +A++N RSGAGV AL +IY +GGYD QL +VERYD +K+ W F A M RSALG T + G+I+V GGYDGN FL SVE +D T++WTE+T M +G+SG V + EP
Sbjct: 27 YTLESHTAAAFAIMNELRRERQLCDVTLRVRYCPLDTHVDFVAHKVVLASSSPVFRAMFTNGLKECGMEVVPIEGIHPKVMGRLIEFAYTASISVGEKCVIHVMNGAVMYQIDSVVQACCDFLVEQLDPSNAIGIASFAEQIGCTELHQKAREYIYMNFSQVATQEEFFTLSHCQLVTLISRDELNVRCESEVFHACVAWVQYDREERRPYVQALLQAVRCHSLTPHFLQRQLEHFEWDAQSK---DYLSQIFRDLTLHKPTKVIPLRTPKVPQLIYTVGGYFRQSLSFLEAFNPCSGAWLRLADLQVPRSGLAACVISGLLYAVGGRNNGPDGNMDSHTLDCYNPMNNCWRPCAHMSVPRNRIGVGVIDGMIYAVGGSHGCT---------HHNSVERYDPERDSWQLVSPMLTRRIGVGVAVINRLLYAVGGFDGTHRLSSAECYNPERDEWRSIAAMNTVRSGAGVCALGNYIYVMGGYDGTNQLNTVERYDVEKDSWSFSASMRHRRSALGVTTHHGRIYVLGGYDGNTFLDSVECFDPETDSWTEVTHMKSGRSGVGVAVTMEP 583
BLAST of Kelch-like ECH-associated protein vs. Ensembl Zebrafish
Match: keap1b (kelch-like ECH-associated protein 1b [Source:ZFIN;Acc:ZDB-GENE-080508-1]) HSP 1 Score: 526.168 bits (1354), Expect = 5.000e-179 Identity = 261/569 (45.87%), Postives = 359/569 (63.09%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKV-----GTEL-FPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + M L +L D+TL+V T + F HKVVLA +S FRAMFT+G++E M +PI GI P V+ RLI F YT I +GE V ++ A M Q+ VV+ACC+FL +Q PSN IGI FA GC +L +KA+ +I NF+++ +EF +L CQL+ I RDELNVR E EVF++ + W +DR R Y+ +L VR H + PHF++ Q+++ ++ +++K L + DL HK P RT Q++Y+ GGY+R SL+ E ++P +G W RL+D+ RSGLAAC + G +Y +GGRNN N D+ +DCY+P N W+ CA MS+PR+R+ VG++D +IYAVGGS + HHNS E++DP+ W V+ M RIG+GVA +NRLLYAVGGFDG +RL S E YNP+ D W +A++N RSGAGV AL +IY +GGYD QL +VERYD +K+ W F A M RSALG T + G+I+V GGYDGN FL SVE +D T++WTE+T M +G+SG V + EP
Sbjct: 27 YTLESHTAAAFAIMNELRRERQLCDVTLRVRYCPLDTHVDFVAHKVVLASSSPVFRAMFTNGLKECGMEVVPIEGIHPKVMGRLIEFAYTASISVGEKCVIHVMNGAVMYQIDSVVQACCDFLVEQLDPSNAIGIASFAEQIGCTELHQKAREYIYMNFSQVATQEEFFTLSHCQLVTLISRDELNVRCESEVFHACVAWVQYDREERRPYVQALLQAVRCHSLTPHFLQRQLEHFEWDAQSK---DYLSQIFRDLTLHKPTKVIPLRTPKVPQLIYTVGGYFRQSLSFLEAFNPCSGAWLRLADLQVPRSGLAACVISGLLYAVGGRNNGPDGNMDSHTLDCYNPMNNCWRPCAHMSVPRNRIGVGVIDGMIYAVGGSHGCT---------HHNSVERYDPERDSWQLVSPMLTRRIGVGVAVINRLLYAVGGFDGTHRLSSAECYNPERDEWRSIAAMNTVRSGAGVCALGNYIYVMGGYDGTNQLNTVERYDVEKDSWSFSASMRHRRSALGVTTHHGRIYVLGGYDGNTFLDSVECFDPETDSWTEVTHMKSGRSGVGVAVTMEP 583
BLAST of Kelch-like ECH-associated protein vs. Ensembl Zebrafish
Match: keap1a (kelch-like ECH-associated protein 1a [Source:ZFIN;Acc:ZDB-GENE-030131-556]) HSP 1 Score: 459.144 bits (1180), Expect = 7.292e-153 Identity = 240/601 (39.93%), Postives = 350/601 (58.24%), Query Frame = 1
Query: 433 IRSEEFT---LNTVSGSGFLCNPTAELISDTFQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTEL----FPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKIN-SPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
I+ E+F+ + ++ G G+L Y ++ + + + +M L L D+ L V + F HK+VLA +S YF+AMFTS +E + E+ + + P VI+RLI F YT I +GE+ V +L A QM V +ACC+FL K PSNVIGI FA GC L + + +I+ +FNE+ + +EF SL CQL+E I +D L V E EV+ + I W D R Y +L+ V ++ +PP F++ Q+++C LS+ + L + ++ K + +PHR Q++Y AGGY +HSL T E + P W +L + + SGL AC + G +Y +GGRN S N ++ + CY+P TN W AP++ PR+RV VG++D IYAVGGS H S HHNS E++DP++ +WT VA M+ R+G GVA LY VGGFDG+NR +VERY PD + W+ VA +N RSG GVV +D ++YA+GGYD QL+++ERY+ ++ W +A M RSA G +VY+ KI+V GG++ FL+SVE Y +N WT +T M G+SG V + EP
Sbjct: 10 IKDEDFSAIVVPSMRGHGYL-------------DYTVESHPSKALQNMDELRHHEMLCDLVLHVTYKDKIVDFKVHKLVLAASSPYFKAMFTSNFKECHASEVTLRDVCPQVISRLIDFAYTSRITVGETCVLHVLLTAMRYQMEEVAKACCDFLMKNLEPSNVIGISRFAEEIGCTDLHLRTREYINTHFNEVTKEEEFFSLSHCQLLELISQDSLKVLCESEVYKACIDWVRWDAESRAQYFHALLNAVHIYALPPTFLKRQLQSCPILSKANSCKDFLSKIFHEMALRKPLPPTPHRG---TQLIYIAGGYKQHSLDTLEAFDPHKNVWLKLGSMMSPCSGLGACVLFGLLYTVGGRNLSLQNNTESGSLSCYNPMTNQWTQLAPLNTPRNRVGVGVIDGSIYAVGGS--------HAST-HHNSVERYDPETNRWTFVAPMSVARLGAGVAACGGCLYVVGGFDGDNRWNTVERYQPDTNTWQHVAPMNTVRSGLGVVCMDNYLYAVGGYDGQTQLKTMERYNITRDVWEPMASMNHCRSAHGVSVYQCKIFVLGGFNQGGFLSSVECYCPASNVWTLVTDMPVGRSGMGVAVTMEP 585
BLAST of Kelch-like ECH-associated protein vs. Ensembl Zebrafish
Match: klhl20 (kelch-like family member 20 [Source:ZFIN;Acc:ZDB-GENE-040426-1935]) HSP 1 Score: 365.54 bits (937), Expect = 8.579e-117 Identity = 201/565 (35.58%), Postives = 298/565 (52.74%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKI-----NSPHRTAGFNQVLYSAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
Y DK+ R+ + + L L D+ L VG + H+V+L+ S YFRAMFT + E E+ I I + LI F YT ++ + E NV LL AA +LQ+ + EACCEFL++Q PSN +GI FA ++ C++L A +F NF E+ +EF+ L QL++ I DELNVRSE +VFN+V+ W + R L ++L HVRL + P F+ + + + ++ R ++ LL Q + + P + +VL++ GG+ ++++ E Y P T +WR ++ + R G+ + +Y +GG + S N V+ YDP+TN W + AP S R V V ++ +YAVGG +S N E++DP +WT VASM+ R+G+ VA + LYAVGG DG + L +VERYNP E+ W VA + R G IY++GG D +L S ERY+P NQW V M RS +G V G++ GG+DG +L ++EVYD NTW M+ + G V
Sbjct: 27 YISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQVTVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLN----SVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCL---------NIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTVAPMGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVYDPDANTWRLYGGMNYRRLGGGV 578 HSP 2 Score: 70.4774 bits (171), Expect = 3.832e-12 Identity = 52/190 (27.37%), Postives = 76/190 (40.00%), Query Frame = 1
Query: 1330 LYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGG--------------------SATLSTQSAHPSV------------------MHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVN 1782
LY+ GG S L E Y P KW R++ + T R G+A + G +Y +GG + + N V+ Y+PQ N W T APM R + + D+IY+VGG S ++ S V + + E +DPD+ W MN R+G GV +
Sbjct: 397 LYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLN----TVERYNPQENRWHTVAPMGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVYDPDANTWRLYGGMNYRRLGGGVGVIK 582
BLAST of Kelch-like ECH-associated protein vs. Ensembl Xenopus
Match: zbtb48 (zinc finger and BTB domain containing 48 [Source:Xenbase;Acc:XB-GENE-984069]) HSP 1 Score: 441.81 bits (1135), Expect = 3.598e-147 Identity = 223/511 (43.64%), Postives = 311/511 (60.86%), Query Frame = 1
Query: 679 MFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
MFT+ RE + E+ I I P V+ RLI F YT I +GE V +L AA QM V +AC +FL K SNVIGI FA GC +L + +I+ +F+E+ +EFLSL C+L++ + +D LNV E EV+N+ ++W D + R Y +L+ V L+ +P F+ Q+K C LS+ R L + +++ HK + P + NQ++Y AGGY ++SL++ + ++P TG+W +L+D+ RSGL AC V G Y +GGRNNS N D+ + ++P TN W + APM++PR+RV V +D IYA GGS HH S EK+DPD+ +WT VA M RIG GV LY VGGFDG+ R +V+ Y+P+ED W+ VAS+ RSGAGVVALD ++YA+GGYD QL SVERY+ ++N W +APM RSA G TV++GKI+ GG++ FL+SVE Y N WTE+T M G SG +V + EP
Sbjct: 1 MFTNNFRECHAREVTIKDICPKVMQRLIEFAYTSRITVGEKCVLHVLLAAMRYQMEDVAKACSDFLVKHLDASNVIGISNFAEQIGCHELYRTGREYINTHFSEVTNEEEFLSLSHCELLDLVSQDSLNVLCESEVYNACLKWMQWDLNNRAQYFHALLNAVHLYSLPAKFLEIQLKKCPILSKENRCRVYLSKIFQEMCLHKPLPRPKQRG--NQLIYVAGGYLQNSLSSMDAFNPQTGEWIKLADMLEPRSGLGACIVSGLFYAVGGRNNSCQENTDSDLLSFFNPVTNQWASRAPMNVPRNRVGVAEIDGAIYAAGGSC---------GSEHHKSVEKYDPDNDRWTFVAPMPTARIGAGVVACRGRLYVVGGFDGDTRWNTVDCYDPEEDQWQPVASMETIRSGAGVVALDNYLYAVGGYDGTNQLDSVERYNIERNYWEAMAPMKHRRSAHGLTVHQGKIYALGGFNAGGFLSSVECYCPDRNEWTEVTVMPTGCSGMSVAVTMEP 500
BLAST of Kelch-like ECH-associated protein vs. Ensembl Xenopus
Match: dcaf8 (DDB1 and CUL4 associated factor 8 [Source:Xenbase;Acc:XB-GENE-989771]) HSP 1 Score: 404.06 bits (1037), Expect = 1.003e-133 Identity = 195/409 (47.68%), Postives = 262/409 (64.06%), Query Frame = 1
Query: 988 EIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHK-KINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
++ + +EF +L CQL+ + RDELNVR E EVF++ I W +D R Y+ +L VR H + P+F++ Q++ C+ L + + L + +DL HK + R Q +Y AGGYYR SL+ E Y+PV G+W L+ + RSGLA C + G Y +GGRNN+ N D+ +DCY+P N W CA MS+PR+RV G++D IYAVGGS +HHNS E++DP+ +W V+ M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ D W+ +AS+N RSGAG ALD +YA+GGYD QL SVERYD +K+ W FVAPM RSALG TV++GKI+V GGYDG+ FL VE Y+ T+TWTE+T+M +G+SG V + EP
Sbjct: 1 QVAKQEEFFNLSSCQLVNLVSRDELNVRCESEVFHACINWVKYDCENRRPYIQALLRAVRCHSLTPNFLQLQLQRCEILKGDSRCQDYLSQIFQDLTLHKPTLPLQGRIPNVPQFIYVAGGYYRQSLSFLEAYNPVDGEWLTLASLEMPRSGLAGCVLGGLFYAVGGRNNAPDCNKDSGALDCYNPMNNQWSPCAAMSVPRNRVGAGVIDGQIYAVGGSH---------GCLHHNSVERYDPERDEWHMVSPMKTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPETDEWKDIASMNIVRSGAGACALDTSVYAMGGYDGTDQLNSVERYDVEKDDWTFVAPMRHRRSALGVTVHQGKIYVLGGYDGSTFLDGVECYNPATDTWTEVTQMTSGRSGVGVAITMEP 400
BLAST of Kelch-like ECH-associated protein vs. Ensembl Xenopus
Match: usb1 (U6 snRNA biogenesis phosphodiesterase 1 [Source:Xenbase;Acc:XB-GENE-948670]) HSP 1 Score: 365.54 bits (937), Expect = 1.907e-116 Identity = 201/565 (35.58%), Postives = 298/565 (52.74%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKI-----NSPHRTAGFNQVLYSAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
Y DK+ R+ + + L L D+ L VG + H+V+L+ S YFRAMFT + E E+ I I + LI F YT +I + E NV LL AA +LQ+ + EACCEFL++Q PSN +GI FA ++ C++L A +F NF E+ +EF+ L QL++ I DELNVRSE +VFN+V+ W + R L ++L HVRL + P F+ + + + ++ R ++ LL Q + + P + +VL++ GG+ ++++ E Y P T +WR ++ + R G+ + +Y +GG + S N V+ YDP+TN W + AP S R V V ++ +YAVGG +S N E++DP +WT VASM+ R+G+ VA + LYAVGG DG + L +VERYNP E+ W +A + R G IYA+GG D +L S ERY+P NQW V M RS +G V G++ GG+DG +L ++EV+D NTW M+ + G V
Sbjct: 38 YVSDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFSYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLN----SVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCL---------NIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGV 589 HSP 2 Score: 73.1738 bits (178), Expect = 9.512e-13 Identity = 54/190 (28.42%), Postives = 76/190 (40.00%), Query Frame = 1
Query: 1330 LYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGG--------------------SATLSTQSAHPSV------------------MHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVN 1782
LY+ GG S L E Y P KW R++ + T R G+A + G +Y +GG + + N V+ Y+PQ N W T APM R + + D+IYAVGG S ++ S V + + E FDPD+ W MN R+G GV +
Sbjct: 408 LYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLN----TVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIK 593
BLAST of Kelch-like ECH-associated protein vs. Ensembl Xenopus
Match: usb1 (U6 snRNA biogenesis phosphodiesterase 1 [Source:Xenbase;Acc:XB-GENE-948670]) HSP 1 Score: 365.155 bits (936), Expect = 2.984e-116 Identity = 201/565 (35.58%), Postives = 298/565 (52.74%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKI-----NSPHRTAGFNQVLYSAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
Y DK+ R+ + + L L D+ L VG + H+V+L+ S YFRAMFT + E E+ I I + LI F YT +I + E NV LL AA +LQ+ + EACCEFL++Q PSN +GI FA ++ C++L A +F NF E+ +EF+ L QL++ I DELNVRSE +VFN+V+ W + R L ++L HVRL + P F+ + + + ++ R ++ LL Q + + P + +VL++ GG+ ++++ E Y P T +WR ++ + R G+ + +Y +GG + S N V+ YDP+TN W + AP S R V V ++ +YAVGG +S N E++DP +WT VASM+ R+G+ VA + LYAVGG DG + L +VERYNP E+ W +A + R G IYA+GG D +L S ERY+P NQW V M RS +G V G++ GG+DG +L ++EV+D NTW M+ + G V
Sbjct: 41 YVSDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFSYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLN----SVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCL---------NIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGV 592 HSP 2 Score: 73.1738 bits (178), Expect = 1.015e-12 Identity = 54/190 (28.42%), Postives = 76/190 (40.00%), Query Frame = 1
Query: 1330 LYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGG--------------------SATLSTQSAHPSV------------------MHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVN 1782
LY+ GG S L E Y P KW R++ + T R G+A + G +Y +GG + + N V+ Y+PQ N W T APM R + + D+IYAVGG S ++ S V + + E FDPD+ W MN R+G GV +
Sbjct: 411 LYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLN----TVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIK 596
BLAST of Kelch-like ECH-associated protein vs. Ensembl Xenopus
Match: usb1 (U6 snRNA biogenesis phosphodiesterase 1 [Source:Xenbase;Acc:XB-GENE-948670]) HSP 1 Score: 365.155 bits (936), Expect = 3.381e-116 Identity = 201/565 (35.58%), Postives = 298/565 (52.74%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKI-----NSPHRTAGFNQVLYSAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
Y DK+ R+ + + L L D+ L VG + H+V+L+ S YFRAMFT + E E+ I I + LI F YT +I + E NV LL AA +LQ+ + EACCEFL++Q PSN +GI FA ++ C++L A +F NF E+ +EF+ L QL++ I DELNVRSE +VFN+V+ W + R L ++L HVRL + P F+ + + + ++ R ++ LL Q + + P + +VL++ GG+ ++++ E Y P T +WR ++ + R G+ + +Y +GG + S N V+ YDP+TN W + AP S R V V ++ +YAVGG +S N E++DP +WT VASM+ R+G+ VA + LYAVGG DG + L +VERYNP E+ W +A + R G IYA+GG D +L S ERY+P NQW V M RS +G V G++ GG+DG +L ++EV+D NTW M+ + G V
Sbjct: 45 YVSDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFSYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLN----SVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSC---------LNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGV 596 HSP 2 Score: 73.1738 bits (178), Expect = 1.022e-12 Identity = 54/190 (28.42%), Postives = 76/190 (40.00%), Query Frame = 1
Query: 1330 LYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGG--------------------SATLSTQSAHPSV------------------MHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVN 1782
LY+ GG S L E Y P KW R++ + T R G+A + G +Y +GG + + N V+ Y+PQ N W T APM R + + D+IYAVGG S ++ S V + + E FDPD+ W MN R+G GV +
Sbjct: 415 LYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLN----TVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIK 600
BLAST of Kelch-like ECH-associated protein vs. Ensembl Mouse
Match: Keap1 (kelch-like ECH-associated protein 1 [Source:MGI Symbol;Acc:MGI:1858732]) HSP 1 Score: 525.013 bits (1351), Expect = 3.929e-178 Identity = 259/568 (45.60%), Postives = 354/568 (62.32%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V E P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E+ + +EF +L CQL I RD+LNVR E EVF++ I W +D R Y+ +L VR H + P F+++Q++ C+ L + + L + ++L HK + P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CA MS+PR+R+ VG++D IYAVGGS +HH+S E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + +N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++GKI+V GGYDG+ FL SVE YD ++TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGVMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEP 612
BLAST of Kelch-like ECH-associated protein vs. Ensembl Mouse
Match: Keap1 (kelch-like ECH-associated protein 1 [Source:MGI Symbol;Acc:MGI:1858732]) HSP 1 Score: 525.013 bits (1351), Expect = 3.929e-178 Identity = 259/568 (45.60%), Postives = 354/568 (62.32%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V E P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E+ + +EF +L CQL I RD+LNVR E EVF++ I W +D R Y+ +L VR H + P F+++Q++ C+ L + + L + ++L HK + P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CA MS+PR+R+ VG++D IYAVGGS +HH+S E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + +N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++GKI+V GGYDG+ FL SVE YD ++TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGVMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEP 612
BLAST of Kelch-like ECH-associated protein vs. Ensembl Mouse
Match: Keap1 (kelch-like ECH-associated protein 1 [Source:MGI Symbol;Acc:MGI:1858732]) HSP 1 Score: 525.013 bits (1351), Expect = 3.929e-178 Identity = 259/568 (45.60%), Postives = 354/568 (62.32%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V E P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E+ + +EF +L CQL I RD+LNVR E EVF++ I W +D R Y+ +L VR H + P F+++Q++ C+ L + + L + ++L HK + P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CA MS+PR+R+ VG++D IYAVGGS +HH+S E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + +N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++GKI+V GGYDG+ FL SVE YD ++TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGVMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEP 612
BLAST of Kelch-like ECH-associated protein vs. Ensembl Mouse
Match: Keap1 (kelch-like ECH-associated protein 1 [Source:MGI Symbol;Acc:MGI:1858732]) HSP 1 Score: 525.013 bits (1351), Expect = 3.929e-178 Identity = 259/568 (45.60%), Postives = 354/568 (62.32%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V E P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E+ + +EF +L CQL I RD+LNVR E EVF++ I W +D R Y+ +L VR H + P F+++Q++ C+ L + + L + ++L HK + P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CA MS+PR+R+ VG++D IYAVGGS +HH+S E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + +N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++GKI+V GGYDG+ FL SVE YD ++TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGVMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEP 612
BLAST of Kelch-like ECH-associated protein vs. Ensembl Mouse
Match: Keap1 (kelch-like ECH-associated protein 1 [Source:MGI Symbol;Acc:MGI:1858732]) HSP 1 Score: 517.309 bits (1331), Expect = 3.455e-175 Identity = 259/568 (45.60%), Postives = 352/568 (61.97%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V E P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E +EF +L CQL I RD+LNVR E EVF++ I W +D R Y+ +L VR H + P F+++Q++ C+ L + + L + ++L HK + P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CA MS+PR+R+ VG++D IYAVGGS +HH+S E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + +N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++GKI+V GGYDG+ FL SVE YD ++TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGVMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGE----EEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEP 608
BLAST of Kelch-like ECH-associated protein vs. UniProt/SwissProt
Match: sp|Q684M4|KEAP1_PIG (Kelch-like ECH-associated protein 1 OS=Sus scrofa OX=9823 GN=KEAP1 PE=3 SV=1) HSP 1 Score: 531.946 bits (1369), Expect = 6.220e-180 Identity = 262/568 (46.13%), Postives = 355/568 (62.50%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKIN-SPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V E P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E+ + +EF +L CQL+ I RD+LNVR E EVF++ I W +D R Y+ +L VR H + PHF++ Q++ C+ L + + L + ++L HK P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CAPMS+PR+R+ VG++D IYAVGGS +HHNS E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + +N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++G+I+V GGYDG+ FL SVE YD T+TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYEDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCAELHQRAREYIYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDCEQRRFYVQALLRAVRCHSLTPHFLQMQLQKCEILQSDSRCKDYLVKIFQELTLHKPTQVMPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEP 612
BLAST of Kelch-like ECH-associated protein vs. UniProt/SwissProt
Match: sp|Q14145|KEAP1_HUMAN (Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2) HSP 1 Score: 528.48 bits (1360), Expect = 1.118e-178 Identity = 261/568 (45.95%), Postives = 356/568 (62.68%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKIN-SPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V + P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E+ + +EF +L CQL+ I RD+LNVR E EVF++ I W +D R Y+ +L VR H + P+F++ Q++ C+ L + + L + E+L HK P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CAPMS+PR+R+ VG++D IYAVGGS +HHNS E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + ++N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++G+I+V GGYDG+ FL SVE YD T+TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREYIYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDCEQRRFYVQALLRAVRCHSLTPNFLQMQLQKCEILQSDSRCKDYLVKIFEELTLHKPTQVMPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEP 612
BLAST of Kelch-like ECH-associated protein vs. UniProt/SwissProt
Match: sp|Q5R774|KEAP1_PONAB (Kelch-like ECH-associated protein 1 OS=Pongo abelii OX=9601 GN=KEAP1 PE=2 SV=1) HSP 1 Score: 528.094 bits (1359), Expect = 1.780e-178 Identity = 261/568 (45.95%), Postives = 356/568 (62.68%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKIN-SPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V + P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E+ + +EF +L CQL+ I RD+LNVR E EVF++ I W +D R Y+ +L VR H + P+F++ Q++ C+ L + + L + E+L HK P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CAPMS+PR+R+ VG++D IYAVGGS +HHNS E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + ++N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++G+I+V GGYDG+ FL SVE YD T+TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREYIYMHFGEVTKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDCEQRRFYVQALLRAVRCHSLTPNFLQMQLQKCEILQSDSRCKDYLVKIFEELTLHKPTQVMPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEP 612
BLAST of Kelch-like ECH-associated protein vs. UniProt/SwissProt
Match: sp|A0A2R8Q1W5|KEP1B_DANRE (Kelch-like ECH-associated protein 1B OS=Danio rerio OX=7955 GN=keap1b PE=1 SV=1) HSP 1 Score: 525.783 bits (1353), Expect = 3.559e-178 Identity = 261/569 (45.87%), Postives = 359/569 (63.09%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKV-----GTEL-FPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + M L +L D+TL+V T + F HKVVLA +S FRAMFT+G++E M +PI GI P V+ RLI F YT I +GE V ++ A M Q+ VV+ACC+FL +Q PSN IGI FA GC +L +KA+ +I NF+++ +EF +L CQL+ I RDELNVR E EVF++ + W +DR R Y+ +L VR H + PHF++ Q+++ ++ +++K L + DL HK P RT Q++Y+ GGY+R SL+ E ++P +G W RL+D+ RSGLAAC + G +Y +GGRNN N D+ +DCY+P N W+ CA MS+PR+R+ VG++D +IYAVGGS + HHNS E++DP+ W V+ M RIG+GVA +NRLLYAVGGFDG +RL S E YNP+ D W +A++N RSGAGV AL +IY +GGYD QL +VERYD +K+ W F A M RSALG T + G+I+V GGYDGN FL SVE +D T++WTE+T M +G+SG V + EP
Sbjct: 21 YTLESHTAAAFAIMNELRRERQLCDVTLRVRYCPLDTHVDFVAHKVVLASSSPVFRAMFTNGLKECGMEVVPIEGIHPKVMGRLIEFAYTASISVGEKCVIHVMNGAVMYQIDSVVQACCDFLVEQLDPSNAIGIASFAEQIGCTELHQKAREYIYMNFSQVATQEEFFTLSHCQLVTLISRDELNVRCESEVFHACVAWVQYDREERRPYVQALLQAVRCHSLTPHFLQRQLEHFEWDAQSK---DYLSQIFRDLTLHKPTKVIPLRTPKVPQLIYTVGGYFRQSLSFLEAFNPCSGAWLRLADLQVPRSGLAACVISGLLYAVGGRNNGPDGNMDSHTLDCYNPMNNCWRPCAHMSVPRNRIGVGVIDGMIYAVGGSHGCT---------HHNSVERYDPERDSWQLVSPMLTRRIGVGVAVINRLLYAVGGFDGTHRLSSAECYNPERDEWRSIAAMNTVRSGAGVCALGNYIYVMGGYDGTNQLNTVERYDVEKDSWSFSASMRHRRSALGVTTHHGRIYVLGGYDGNTFLDSVECFDPETDSWTEVTHMKSGRSGVGVAVTMEP 577
BLAST of Kelch-like ECH-associated protein vs. UniProt/SwissProt
Match: sp|Q9Z2X8|KEAP1_MOUSE (Kelch-like ECH-associated protein 1 OS=Mus musculus OX=10090 GN=Keap1 PE=1 SV=1) HSP 1 Score: 525.013 bits (1351), Expect = 2.748e-177 Identity = 259/568 (45.60%), Postives = 354/568 (62.32%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPC-----HKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + ++ M L L+ +L D+TL+V E P HKVVLA +S F+AMFT+G+RE M + I GI P V+ RLI F YT I +GE V ++ A M Q+ VV AC +FL +Q PSN IGI FA GC +L ++A+ +I +F E+ + +EF +L CQL I RD+LNVR E EVF++ I W +D R Y+ +L VR H + P F+++Q++ C+ L + + L + ++L HK + P R +++Y+AGGY+R SL+ E Y+P G W RL+D+ RSGLA C V G +Y +GGRNNS N D+ +DCY+P TN W CA MS+PR+R+ VG++D IYAVGGS +HH+S E+++P+ +W VA M RIG+GVA +NRLLYAVGGFDG NRL S E Y P+ + W + +N RSGAGV L IYA GGYD QL SVERYD + W FVAPM RSALG TV++GKI+V GGYDG+ FL SVE YD ++TW+E+T+M +G+SG V + EP
Sbjct: 54 YTLEDHTKQAFGVMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSH---------GCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEP 612
BLAST of Kelch-like ECH-associated protein vs. TrEMBL
Match: A0A094ZZP1 (Kelch-like ECH-associated protein 1 OS=Schistosoma haematobium OX=6185 GN=MS3_07048 PE=4 SV=1) HSP 1 Score: 737.643 bits (1903), Expect = 0.000e+0 Identity = 358/626 (57.19%), Postives = 458/626 (73.16%), Query Frame = 1
Query: 367 MSDNIEDYPVTPLHSQNVIDSRIRSEEFTLNTVSGSGFLCNPTAELISDT---------FQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQF 2217
M +N+ED+P+ L S + + I S L + F+ +PT L + + +++ + Y +E MN+MY LF + +LTD+TL V +E CH++VLAGAS YFRAMFT MRE +HEI +H IS + +LI F YTG I I E NVCELL AA+M+QM HVV+ACC FL++Q HPSN IGI EFA SN C +L+ AQ+FID+NF+EI ++DEFL L P QL+ IKRDELNVR+E EV+N+VIRW NH+R+ R+ LLE LS VR + +PP FI+ QIKNC L+ +S L+++L+DL++H+ I+ RTAG ++LYSAGGY R+SL+ FECY+PVT KWRRL DIP+ RSGL+ACSV VYL+GGRNN+E N D PH+DCYDP+ N W TCAPMS+PR+RVAVG+VDD+IYAVGGS + MHH S+EK+DPD QW P+ASMN+ RIGLGVA +NRLLYAVGGFDGE RL +VERY+P++DNWE +A LNR RSGAGVVAL ++IYAIGGYDS QL ++ERYDP +N W + A M+ PRSAL A+V+ +IWVFGGYDG+EFL SVEVY+ + WTE T MD GKSGHAV++ R P F
Sbjct: 3 MKENVEDFPMDEL-SVSSTNCDISSSFPDL--ANSELFIPHPTYILPTCSSDESNDNLICMNFESNHYLKEAMNTMYELFQSRKLTDVTLCVNSESIQCHRIVLAGASPYFRAMFTGEMREALLHEIKLHYISASALKKLIDFAYTGRIQISERNVCELLIAASMIQMSHVVQACCSFLKQQLHPSNAIGIQEFAQSNNCSELSFAAQKFIDQNFSEIVKHDEFLGLHPNQLLTLIKRDELNVRTEAEVYNAVIRWVNHNRNSRSSTLLEALSAVRCYTLPPTFIQGQIKNCSLLAGFTPAKSHLQNILDDLIKHRHISINKRTAGSMEILYSAGGYLRYSLSAFECYNPVTAKWRRLPDIPSPRSGLSACSVRSCVYLVGGRNNNEQGNIDAPHMDCYDPRKNCWTTCAPMSVPRNRVAVGVVDDMIYAVGGST---------NTMHHKSSEKYDPDMDQWIPIASMNSRRIGLGVAVLNRLLYAVGGFDGEKRLNTVERYDPEKDNWEELACLNRARSGAGVVALGEYIYAIGGYDSCSQLNTMERYDPKRNCWEYCASMLHPRSALSASVWGNEIWVFGGYDGSEFLASVEVYNPIKDQWTERTFMDCGKSGHAVVVSRGPSF 616
BLAST of Kelch-like ECH-associated protein vs. TrEMBL
Match: G4VRQ7 (Kelch-like ech-associated protein OS=Schistosoma mansoni OX=6183 GN=Smp_085380 PE=4 SV=1) HSP 1 Score: 736.873 bits (1901), Expect = 0.000e+0 Identity = 355/626 (56.71%), Postives = 459/626 (73.32%), Query Frame = 1
Query: 367 MSDNIEDYPVTPLHSQNVIDSRIRSEEFTLNTVSGSGFLCNPTAELISDT---------FQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQF 2217
M +N+ED+P+ L + +R S F + + ++ +PT L + + +++++ Y +E MN+MY LF + +LTD+TL V +E CH++VLAGAS YFRAMFT MRE +HEI +H IS + +LI F YTG I I E NVCELL AA+M+QM HVV+ACC FL++Q HPSN IGI EFA SN C +L+ AQ+FID+NF EI ++DEFL L P QL+ IKRDELNVR+E EV+N+VIRW NH+R+ R+ LLE LS VR + +PP FI+ QIKNC L+ +S L+++L+DL++H+ I+ RTAG ++LYSAGGY R+SL+ FECY+P+T KWRRL DIP+ RSGL+ACSV G VYL+GGRNN+E N D PH+DCYDP+ N W TCAPMS+PR+RVAVG+VDD+IYAVGGS + MHH S+EK+DPD QW P+ASMN+ RIGLGVA +NRLLYAVGGFDGE RL +VERY+P++D+WE +A LNR RSGAGVVAL ++IYAIGGYDS QL ++ERYDP +N W + A M+ PRSAL A+V+ +IWVFGGYDG+EFL SVEVY+ + WTE T MD GKSGHAV++ R P F
Sbjct: 3 MKENVEDFPMDELSVSST--NRDISSSFP-DLANSELYIPHPTYILPTCSSNESNDNLICMNFELNHYLKEAMNTMYELFQSQKLTDVTLCVNSESIQCHRIVLAGASPYFRAMFTGEMREALLHEIKLHYISATALKKLIDFAYTGRIQISERNVCELLIAASMIQMSHVVQACCSFLKQQLHPSNAIGIQEFAQSNNCSELSFAAQKFIDQNFGEIVKHDEFLGLHPNQLLTLIKRDELNVRTEAEVYNAVIRWVNHNRNSRSSTLLEALSAVRCYTLPPTFIQGQIKNCSLLAGFTPAKSHLQNILDDLIKHRHISINKRTAGSMEILYSAGGYLRYSLSAFECYNPLTDKWRRLPDIPSPRSGLSACSVRGCVYLVGGRNNNEQGNIDAPHMDCYDPRKNCWTTCAPMSVPRNRVAVGVVDDMIYAVGGST---------NTMHHKSSEKYDPDMDQWIPIASMNSRRIGLGVAVLNRLLYAVGGFDGEKRLNTVERYDPEKDHWEELACLNRARSGAGVVALGEYIYAIGGYDSCSQLNTMERYDPKRNCWEYCASMLHPRSALSASVWGNEIWVFGGYDGSEFLASVEVYNPIKDQWTERTFMDCGKSGHAVVVSRGPSF 616
BLAST of Kelch-like ECH-associated protein vs. TrEMBL
Match: A0A430QQ22 (Kelch-like protein 19 OS=Schistosoma bovis OX=6184 GN=DC041_0000022 PE=4 SV=1) HSP 1 Score: 734.561 bits (1895), Expect = 0.000e+0 Identity = 356/626 (56.87%), Postives = 457/626 (73.00%), Query Frame = 1
Query: 367 MSDNIEDYPVTPLHSQNVIDSRIRSEEFTLNTVSGSGFLCNPTAELISDT---------FQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQF 2217
M +N+ED+P+ L + +R S F + + F+ +PT L + + +++ + Y +E MN+MY LF + +LTD+TL V +E CH++VLAGAS YFRAMFT MRE +HEI +H IS + +LI F YTG I I E NVCELL AA+M+QM HVV+ACC FL++Q HPSN IGI EFA SN +L+ AQ+FID+NF+EI ++DEFL L P QL+ IKRDELNVR+E EV+N+VIRW NH+R+ R+ LLE LS VR + +PP FI+ QIKNC L+ +S L+++L+DL++H+ I+ RTAG ++LYSAGGY R+SL+ FECY+PVT KWRRL DIP+ RSGL+ACSV VYL+GGRNN+E N D PH+DCYDP+ N W TCAPMS+PR+RVAVG+VDD+IYAVGGS + MHH S+EK+DPD QW P+ASMN+ RIGLGVA +NRLLYAVGGFDGE RL +VERY+P++DNWE +A LNR RSGAGVVAL ++IYAIGGYDS QL ++ERYDP +N W + A M+ PRSAL A+V+ +IWVFGGYDG+EFL SVEVY+ + WTE T MD GKSGHAV++ R P F
Sbjct: 3 MKENVEDFPMDELSVSST--NRDISSSFP-DLANSELFIPHPTYILPTCSSDESNDNLICMNFESNHYLKEAMNTMYELFQSRKLTDVTLCVNSESIQCHRIVLAGASPYFRAMFTGEMREALLHEIKLHYISASALKKLIDFAYTGRIQISERNVCELLIAASMIQMSHVVQACCSFLKQQLHPSNAIGIQEFAQSNNFSELSFAAQKFIDQNFSEIVKHDEFLGLHPNQLLTLIKRDELNVRTEAEVYNAVIRWVNHNRNSRSSTLLEALSAVRCYTLPPTFIQGQIKNCSLLAGFTPAKSHLQNILDDLIKHRHISINKRTAGSMEILYSAGGYLRYSLSAFECYNPVTAKWRRLPDIPSPRSGLSACSVRSCVYLVGGRNNNEQGNIDAPHMDCYDPRKNCWTTCAPMSVPRNRVAVGVVDDMIYAVGGST---------NTMHHKSSEKYDPDMDQWIPIASMNSRRIGLGVAVLNRLLYAVGGFDGEKRLNTVERYDPEKDNWEELACLNRARSGAGVVALGEYIYAIGGYDSCSQLNTMERYDPKRNCWEYCASMLHPRSALSASVWGNEIWVFGGYDGSEFLASVEVYNPIKDQWTERTFMDCGKSGHAVVVSRGPSF 616
BLAST of Kelch-like ECH-associated protein vs. TrEMBL
Match: C1L531 (Kelch-like ECH-associated protein 1 OS=Schistosoma japonicum OX=6182 PE=2 SV=1) HSP 1 Score: 728.398 bits (1879), Expect = 0.000e+0 Identity = 353/627 (56.30%), Postives = 455/627 (72.57%), Query Frame = 1
Query: 367 MSDNIEDYPVTPLHSQNVIDSRIRSEEFTLNTVSGSG-FLCNPTAELISDT---------FQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQF 2217
M +N+ED+P+ L +V+ + + ++ SG ++ +PT L + + +++++ Y +E MN+MY LF + +LTD+TL V +E F CH++VLAGAS YFRAMFT MRE + EI +H IS + +LI F YTG I I E NVCELL AA+++QM HVV ACC FL+ Q HPSN IGI EFA SN C +L+ AQ+FID+NF EI ++DEFL L P QL+ IKRDELNVR+E EV+N+VIRW NH+R+ R LE LS VR + +PP FI+ QIKNC L+ +S L+++L+DL++H+ I+ RTAG ++LYSAGGY R+SL+ FECY+P+T KWRRL DIP+ RSGL+ACSV G VYL+GGRNN+E N D PH+DCYDP+ N W TCAPMS+PR+RVAVG+VDD+IYAVGGS + +HH S+EK+DPD QW P+ASM++ RIGLGVA +NRLLYAVGGFDGE RL +VERYNP+ DNWE +A LNR RSGAGVVAL + IYAIGGYDS QL ++ERYDP +N W + A M+ PRSAL A+V+ +IWVFGGYDG+EFL SVEVY+ + WTE T MD GKSGHAV++ R P F
Sbjct: 3 MKENVEDFPMDEL---SVLSANHSVSPSSFPDLTNSGLYIPHPTYILPTCSSDDSNDNLICMNFELNHYLKEAMNNMYELFQSQKLTDVTLCVNSESFQCHRIVLAGASPYFRAMFTGEMREALLPEIKLHYISATALKKLIDFAYTGRIQISERNVCELLIAASIIQMSHVVHACCSFLKHQLHPSNAIGIQEFAQSNNCSELSFTAQKFIDQNFGEIVKHDEFLGLHPNQLLSLIKRDELNVRTEAEVYNAVIRWVNHNRNSRLSTFLEALSAVRCYTLPPTFIQGQIKNCNLLAGFTPAKSHLQNILDDLIKHRHISVNKRTAGSMEILYSAGGYLRYSLSAFECYNPITAKWRRLPDIPSPRSGLSACSVRGCVYLVGGRNNNEQGNIDAPHMDCYDPRKNCWTTCAPMSVPRNRVAVGVVDDMIYAVGGST---------NTIHHKSSEKYDPDMDQWIPIASMHSRRIGLGVAVLNRLLYAVGGFDGEKRLNTVERYNPETDNWEELACLNRARSGAGVVALGEFIYAIGGYDSCSQLNTMERYDPKRNCWEYCASMLHPRSALSASVWGNEIWVFGGYDGSEFLASVEVYNPVKDQWTERTFMDCGKSGHAVVVSRGPLF 617
BLAST of Kelch-like ECH-associated protein vs. TrEMBL
Match: A0A4E0R5C4 (Kelch repeat type 1 OS=Fasciola hepatica OX=6192 GN=D915_006899 PE=4 SV=1) HSP 1 Score: 719.153 bits (1855), Expect = 0.000e+0 Identity = 334/565 (59.12%), Postives = 423/565 (74.87%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQFE 2220
+ + +Y+ E MN M+ L+LAG LTD+TL V + CH++VL GAS YFRAMF + MRE M +I +H IS + L+ F YTG+I I E NVCELL A++M+QM+HV+EACC FLE Q HPSNVIGI EFASSN C LA AQ F+D+NFNE+ +YDEFL++ P QL IKRD L+VR+E EV+N++IRW NHDRS R L++ L VR H + P+FIRSQIKNC L+ + L+SVL DL++H+ + RTAG +++LYSAGGY R+SL+ FECY+P T KWR+L DIP+ RSGL+ACSV G VYL+GGRNN+E N D PH+DCYDP NSW TCAPMS+PR+RVAVG++DD+IYA+GGS + + HNS E +D D G+WTP+A M RIGLGVA +NRLLYAVGGFDGE RL +VERY+P+ D+WE +ASLNR RSGAGVV + QHIYA+GGYDS QLR+VERY+P++N W + A M+ PRSAL A V + +IWVFGGYDGNEFL+S+EVYD T+ WTE MD GKSGHA+++ REP +
Sbjct: 57 FDVSEYHSEAMNVMHDLYLAGTLTDVTLIVESNQIQCHRIVLVGASPYFRAMFCTNMRESEMAKIELHCISTNALRMLVEFAYTGKIRIDEHNVCELLTASSMVQMNHVIEACCTFLEHQLHPSNVIGICEFASSNNCTGLALAAQTFLDQNFNEVVKYDEFLAVTPTQLFSMIKRDNLSVRTEAEVYNAMIRWINHDRSSRLSLLVDALYVVRCHTLSPNFIRSQIKNCSLLAGVPSAKMHLQSVLRDLVEHRNVLMRRRTAGSSEILYSAGGYLRYSLSAFECYNPRTNKWRQLPDIPSPRSGLSACSVRGCVYLVGGRNNNEQGNIDAPHMDCYDPVANSWHTCAPMSVPRNRVAVGVIDDMIYAIGGST---------NTLPHNSCEVYDSDLGRWTPIACMRYRRIGLGVAVLNRLLYAVGGFDGERRLSTVERYDPETDSWEELASLNRARSGAGVVTVGQHIYAVGGYDSCSQLRTVERYNPERNMWEYRASMLHPRSALSAAVLDNEIWVFGGYDGNEFLSSIEVYDPTTDQWTERAFMDCGKSGHAIVVSREPHLK 612
BLAST of Kelch-like ECH-associated protein vs. Ensembl Cavefish
Match: keap1b (kelch like ECH associated protein 1 [Source:NCBI gene;Acc:103045265]) HSP 1 Score: 531.946 bits (1369), Expect = 0.000e+0 Identity = 264/572 (46.15%), Postives = 364/572 (63.64%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVG-TEL----FPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS-PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQFED 2223
Y ++ + M L L +L D+TL+V +L F HKVVLA +S FRAMFT+G++E M +PI GI P V+ RLI F YT I +GE V ++ A M Q+ VV+ACC+FL +Q PSN IGI FA GC +L +KA+ +I NF+++ +EF +L CQL+ I RDELNVR E EVF++ + W +DR R Y+ +L VR H + P+F++ Q+++ ++ +++K L + +DL HK RT Q++Y+AGGY+R SL E ++P++G W RL+D+ RSGLA+C + G Y +GGRNN+ N D+ +DCY+P N W CAPMS+PR+R+ VG++D +IYAVGGS +HHNS E++DP+ W VA M RIG+GVA +NRLLYAVGGFDG +RL SVE YNP++D W+ AS+N RSGAGV AL HI+ +GGYD QL +VERYD + + W F++ M RSALG T + +I+ GGYDGN FL SVE YD T+TWTE+TKM +G+SG V + EP +D
Sbjct: 27 YTLESHTGAAFAIMNELRLERQLCDVTLRVKYNDLEAVDFVAHKVVLASSSPVFRAMFTNGLKECGMEVVPIEGIHPRVMGRLIEFAYTASISVGEKCVIHVMNGAVMYQIDSVVKACCDFLVQQLDPSNAIGIANFAEQIGCTELHQKAREYIYMNFSQVATQEEFFNLSHCQLVTLISRDELNVRCESEVFHACVAWVQYDRENRRPYVQALLQAVRCHSLTPNFLQRQLEHFEWDAQSK---DYLSQIFQDLTLHKPTKVISCRTPKVPQLIYTAGGYFRQSLCYLEAFNPISGAWLRLADLQVPRSGLASCVISGLFYAVGGRNNAPDGNMDSNTLDCYNPMNNCWLPCAPMSVPRNRIGVGVIDGMIYAVGGSH---------GCIHHNSVERYDPERDIWQLVAPMLTRRIGVGVAVINRLLYAVGGFDGTHRLSSVECYNPEKDEWKSTASMNTVRSGAGVCALGNHIFVMGGYDGTNQLNTVERYDVETDSWTFISSMRHRRSALGVTTHHSRIYALGGYDGNTFLDSVECYDPETDTWTEVTKMTSGRSGVGVAVTMEPCQKD 586
BLAST of Kelch-like ECH-associated protein vs. Ensembl Cavefish
Match: keap1b (kelch like ECH associated protein 1 [Source:NCBI gene;Acc:103045265]) HSP 1 Score: 526.939 bits (1356), Expect = 1.139e-179 Identity = 260/559 (46.51%), Postives = 358/559 (64.04%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVG-TEL----FPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPH-RTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSG 2184
Y ++ + M L L +L D+TL+V +L F HKVVLA +S FRAMFT+G++E M +PI GI P V+ RLI F YT I +GE V ++ A M Q+ VV+ACC+FL +Q PSN IGI FA GC +L +KA+ +I NF+++ +EF +L CQL+ I RDELNVR E EVF++ + W +DR R Y+ +L VR H + P+F++ Q+++ ++ +++K L + +DL HK RT Q++Y+AGGY+R SL E ++P++G W RL+D+ RSGLA+C + G Y +GGRNN+ N D+ +DCY+P N W CAPMS+PR+R+ VG++D +IYAVGGS +HHNS E++DP+ W VA M RIG+GVA +NRLLYAVGGFDG +RL SVE YNP++D W+ AS+N RSGAGV AL HI+ +GGYD QL +VERYD + + W F++ M RSALG T + +I+ GGYDGN FL SVE YD T+TWTE+TKM +G+SG
Sbjct: 27 YTLESHTGAAFAIMNELRLERQLCDVTLRVKYNDLEAVDFVAHKVVLASSSPVFRAMFTNGLKECGMEVVPIEGIHPRVMGRLIEFAYTASISVGEKCVIHVMNGAVMYQIDSVVKACCDFLVQQLDPSNAIGIANFAEQIGCTELHQKAREYIYMNFSQVATQEEFFNLSHCQLVTLISRDELNVRCESEVFHACVAWVQYDRENRRPYVQALLQAVRCHSLTPNFLQRQLEHFEWDAQSK---DYLSQIFQDLTLHKPTKVISCRTPKVPQLIYTAGGYFRQSLCYLEAFNPISGAWLRLADLQVPRSGLASCVISGLFYAVGGRNNAPDGNMDSNTLDCYNPMNNCWLPCAPMSVPRNRIGVGVIDGMIYAVGGSH---------GCIHHNSVERYDPERDIWQLVAPMLTRRIGVGVAVINRLLYAVGGFDGTHRLSSVECYNPEKDEWKSTASMNTVRSGAGVCALGNHIFVMGGYDGTNQLNTVERYDVETDSWTFISSMRHRRSALGVTTHHSRIYALGGYDGNTFLDSVECYDPETDTWTEVTKMTSGRSG 573
BLAST of Kelch-like ECH-associated protein vs. Ensembl Cavefish
Match: keap1a (kelch-like ECH-associated protein 1 [Source:NCBI gene;Acc:103040234]) HSP 1 Score: 434.106 bits (1115), Expect = 3.408e-143 Identity = 228/566 (40.28%), Postives = 332/566 (58.66%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTEL----FPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y I+ + M L G L D+ L V + F HK+VLA S YF+AMFTS +E EI + + P VI RL+++ YT +GE V +L A QM V +ACC+FL K SNVIGI FA GC +L ++++ +I+ +F+E+ + +EF SL CQL+E I ++ L V E EV+ + I W D R Y +L+ V ++ +P F++ Q+++C LS+ + L + +++ K + P NQ++Y +GGY + SLA+ E + P W +L+++ T SGL AC + G Y +GGRN S N D+ + CY+P TN W A ++ PR+RV +G +D IYAVGGS H S MHHN+ E++DP++ +WT V M+ R+G GVA LY VGGFDGENR SVER+ PD + W+ VA ++ RSG GVV +D ++YA+GGYD QL ++ERY+ ++ W +A M RSA G TVY+GK++VFGG++ + FL+SVE Y +N WT +T M G+SG V + EP
Sbjct: 31 YTIESHPSRAFQLMDELRHHGLLCDLVLHVTYKDRVVDFKVHKLVLAACSPYFKAMFTSNFKECKASEITLRDVCPTVIERLVNYAYTSRFTVGEKCVLHILLGAMRYQMEDVAKACCDFLVKNLEASNVIGISRFAEEIGCVELHQRSREYINTHFSEVIKEEEFFSLSHCQLLELISQESLKVLCETEVYKACIDWVRWDVEGRAQYFHALLNAVHIYALPAKFLKRQLQSCPILSKANSCKDFLSKIFQEMTLRKPL--PPTPLRGNQLIYMSGGYNQQSLASMEAFDPHRKAWLKLAEMDTPCSGLGACVLFGLFYSVGGRNLSLQSNVDSEALCCYNPMTNQWTQLASLNTPRNRVGIGELDGSIYAVGGS--------HGS-MHHNTVERYDPEANRWTFVTPMSVSRLGAGVAACGGALYVVGGFDGENRWKSVERFQPDTNTWQHVAPMSTVRSGLGVVCIDSYLYAVGGYDCQTQLNTMERYNVSRDVWEPMASMGHCRSAHGVTVYQGKLFVFGGFNQSGFLSSVECYCPASNQWTYVTDMPVGRSGMGVAVTMEP 585
BLAST of Kelch-like ECH-associated protein vs. Ensembl Cavefish
Match: klhl20 (kelch like family member 20 [Source:NCBI gene;Acc:103022090]) HSP 1 Score: 365.54 bits (937), Expect = 6.536e-117 Identity = 201/565 (35.58%), Postives = 298/565 (52.74%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKI-----NSPHRTAGFNQVLYSAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
Y DK+ R+ + + L L D+ L VG + H+V+L+ S YFRAMFT + E E+ I I + LI F YT ++ + E NV LL AA +LQ+ + EACCEFL++Q PSN +GI FA ++ C++L A +F NF E+ +EF+ L QL++ I DELNVRSE +VFN+V+ W + R L ++L HVRL + P F+ + + + ++ R ++ LL Q + + P + +VL++ GG+ ++++ E Y P T +WR ++ + R G+ + +Y +GG + S N V+ YDP+TN W + AP S R V V ++ +YAVGG +S N E++DP +WT VASM+ R+G+ VA + LYAVGG DG + L +VERYNP E+ W VA + R G IY++GG D +L S ERY+P NQW V M RS +G V G++ GG+DG +L ++EVYD NTW M+ + G V
Sbjct: 27 YVSDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQVTVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLN----SVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCL---------NIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTVAPMGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVYDPDANTWRLYGGMNYRRLGGGV 578 HSP 2 Score: 70.4774 bits (171), Expect = 3.248e-12 Identity = 52/190 (27.37%), Postives = 76/190 (40.00%), Query Frame = 1
Query: 1330 LYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGG--------------------SATLSTQSAHPSV------------------MHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVN 1782
LY+ GG S L E Y P KW R++ + T R G+A + G +Y +GG + + N V+ Y+PQ N W T APM R + + D+IY+VGG S ++ S V + + E +DPD+ W MN R+G GV +
Sbjct: 397 LYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLN----TVERYNPQENRWHTVAPMGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVYDPDANTWRLYGGMNYRRLGGGVGVIK 582
BLAST of Kelch-like ECH-associated protein vs. Ensembl Cavefish
Match: KLHL12 (kelch like family member 12 [Source:NCBI gene;Acc:103031735]) HSP 1 Score: 353.599 bits (906), Expect = 1.245e-112 Identity = 197/568 (34.68%), Postives = 300/568 (52.82%), Query Frame = 1
Query: 535 DKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQ---HKKINSPHRTA--GFNQVLYSAGGY--YRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYD---PQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGRE 2208
+ + + +N+M L + L DITL+V FP H++VLA S YF AMFTS + E + I G++ + L+ F+YT +L+ NV ELL AA +LQ+ V ACC+FL Q PSN +GI +FA ++ C L + A+ F K+F+E+ +++EF+ L ++ + IK DE+ V SE VF +V+ W H+R R YL ++L +VR+ + P +I I + + + R ++ + L+ ++ P A G +VL GG+ + + E Y P T +W L +I R +A S++ RVY+IGG + + V+C D + W T A M++ R + D+IY GG H S E++DP+ QW+ + M R G G+ + L+Y +GG+DG N L SVERY+P +W V + RSGAGV L+ HIY +GG+D L SVE Y+ + W VAPM PR +GATV G+++ GYDGN L+S+E YD ++W +T M + V + RE
Sbjct: 9 NSHAKSILNAMNALRKSNTLCDITLRVENTDFPAHRIVLAACSDYFCAMFTSELAEKGKSFVDIQGLTASTMEILLDFVYTETVLVTVENVQELLPAACLLQLKGVKRACCDFLNSQLDPSNCLGIRDFAETHNCVDLMQAAELFSQKHFSEVVQHEEFMLLSQTEVEKLIKCDEIQVDSEEPVFEAVLNWVKHNRKEREPYLSDMLEYVRMPLLTPRYITDVIDSEPLIRCSLACRDLVDEAKKFHLRPELRSEMQGPRTQARLGAKEVLLVIGGFGSQQSPIDVVEKYDPKTQEWSFLPNIARKRRYVATVSLNDRVYVIGGYDGRSRLS----SVECLDYTADEDGVWYTVATMNVRRGLAGATTLGDMIYVAGG---------FDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGLIYCLGGYDGLNILNSVERYDPHTGHWTSVTPMANKRSGAGVALLNDHIYVVGGFDGTAHLASVEVYNIRTDYWTTVAPMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPVLDSWEVVTSMATQRCDAGVCVLRE 563
BLAST of Kelch-like ECH-associated protein vs. Ensembl Sea Lamprey
Match: klhl18 (kelch-like family member 18 [Source:ZFIN;Acc:ZDB-GENE-030131-5785]) HSP 1 Score: 345.51 bits (885), Expect = 6.287e-110 Identity = 198/565 (35.04%), Postives = 288/565 (50.97%), Query Frame = 1
Query: 496 AELISDTFQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS--PHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAAC-SVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKS 2181
A+ D H+ +D + M + G+L D+TL+VG + H+VVLA + YF AMFT+ M E EI + G P + LI+F Y G + I + NV LL AA+ LQ+H V +ACC FL+++ HP NV+G+ FA + C L + A F+ ++F E +EFL L +L+E RDEL+V E +VF +V+ W DR R L ++L+ VRL PHF+ +++ ++++ R+C + DLL K P R PV +P ++ C S+ GRVY +GG N++ V+ YDP TN W+ C PM PR RV V ++ +YAVGGS S S E +DPD WT VASMN+ R +GVA ++ +Y GG+DG + L SVE Y+ + D W V ++N RS GV + +Y GG+D +VE Y+P W APM + R GA G+++ GGY G+ FL+SVE YD ++ W+ +T M A +S
Sbjct: 14 ADDFEDDIVHFSVDDLAVKGFGVMEEIRRQGKLCDVTLRVGEHKYSAHRVVLAASIPYFHAMFTTDMAESKREEIVMQGTDPSALEALINFAYNGRVAIDQHNVQALLMAASFLQLHAVKDACCHFLKERLHPKNVLGVRSFAEAMMCPALYDTANSFLQQHFVEASSGEEFLGLPGEELLELAARDELHVEGEEQVFEAVLAWVRRDREGRAPLLPDLLTCVRLPLCRPHFLTDRVQ------QDELIRACHKC--RDLLDEAKDYHLMPDR-------------------------RPV---------LPAYKTRPRCCTSLAGRVYAVGGLNSA---GDAVTMVEVYDPLTNRWEACCPMGSPRSRVGVAVLGGRLYAVGGSDGQERLS---------SVEVYDPDRNIWTKVASMNSKRSAMGVAVLDGQIYVCGGYDGVSSLSSVECYSSEADKWTMVTAMNSPRSATGVAFFEGRVYVTGGHDGLQIFNTVEYYNPHTGSWHKAAPMQQRRCRHGAAALSGRLYAVGGYTGSAFLSSVETYDTASDQWSALTPMLASRS 524 HSP 2 Score: 144.821 bits (364), Expect = 1.049e-36 Identity = 81/197 (41.12%), Postives = 107/197 (54.31%), Query Frame = 1
Query: 1621 IYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGH--AVLLGR 2205
+YAVGG SA +V E +DP + +W M + R +GVA + LYAVGG DG+ RL SVE Y+PD + W VAS+N RS GV LD IY GGYD L SVE Y + ++W V M PRSA G +EG+++V GG+DG + +VE Y+ T +W + M + H A L GR
Sbjct: 299 VYAVGG-----LNSAGDAV---TMVEVYDPLTNRWEACCPMGSPRSRVGVAVLGGRLYAVGGSDGQERLSSVEVYDPDRNIWTKVASMNSKRSAMGVAVLDGQIYVCGGYDGVSSLSSVECYSSEADKWTMVTAMNSPRSATGVAFFEGRVYVTGGHDGLQIFNTVEYYNPHTGSWHKAAPMQQRRCRHGAAALSGR 487 HSP 3 Score: 105.531 bits (262), Expect = 6.998e-24 Identity = 67/198 (33.84%), Postives = 97/198 (48.99%), Query Frame = 1
Query: 1330 LYSAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVAL 1920
+Y GGY SL++ ECYS KW ++ + + RS GRVY+ GG + +++N V+ Y+P T SW APM R R + +YAVGG T SA S S E +D S QW+ + M R + +A + LYA+GG+DG LG+VE + P+ + W A ++ G G L
Sbjct: 394 IYVCGGYDGVSSLSSVECYSSEADKWTMVTAMNSPRSATGVAFFEGRVYVTGGHDGLQIFN----TVEYYNPHTGSWHKAAPMQQRRCRHGAAALSGRLYAVGGY----TGSAFLS-----SVETYDTASDQWSALTPMLASRSRVALAACSGRLYALGGYDGYANLGTVECFTPESNTWRQAAQMSWHTGGVGTGCL 578
BLAST of Kelch-like ECH-associated protein vs. Ensembl Sea Lamprey
Match: klhl5 (kelch-like family member 5 [Source:ZFIN;Acc:ZDB-GENE-080424-7]) HSP 1 Score: 321.242 bits (822), Expect = 9.539e-101 Identity = 197/587 (33.56%), Postives = 305/587 (51.96%), Query Frame = 1
Query: 490 PTAEL-ISDTFQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKI------NSPHR-TAGFNQVLYSAGGYYRHSLAT-FECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSA----CQLRS--VERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGR 2205
P E+ S + + +Q + + M +L D+ L G P H++VL+ S YF AMFTS +RE E+ + G+ P + L+ + YTG + + E + LLAAA +LQ+ VVEACC FL KQ HPSN +GI FA + GC L + A + +NF E+ R EFL L + + +E+NV E VF +++ W H+ R L +L+HVRL + P F+ N + + R L+++ LL ++ P + T G +++ GG AT E Y T W +++ + R + +VY++GGR+ + N V+CY+P+T++W PMS RH + V +++ +YAVGG H + N+ E++DP + QW VA+M+N R +GVA +N LYAVGG DG + L SVE ++P + W A + + R G GV A + +YA+GG+D+ C S VER+DP + W VAP+ R A+G + +++ GGYDG +L +VE YD N WT++ + G++G V+ R
Sbjct: 14 PAMEVATSSSEESFQALNHAEQMARRMEGYLRHKQLCDVVLLAGDRRIPAHRLVLSSVSDYFAAMFTSDVREAKQEEVKLEGVEPTALWALVQYAYTGRLDLREDTIEGLLAAACLLQLSPVVEACCGFLMKQLHPSNCLGIRSFADAQGCTDLHKVAHNYTMENFLEVMRNQEFLLLPTEAVADLFASEEMNVPGEETVFQALMAWVMHEVETRRHVLPGLLAHVRLPLLSPQFLGDLESNPLLCDDVECQRLLLQAMKYHLLPERRPAMQGASTRPRKSTVG---TMFAVGGMDATKGATSIERYDLRTNTWTQVAMLSGRRLQFGVAVLDDKVYVVGGRDGLKTLNT----VECYNPRTHTWSVLPPMSTHRHGLGVAVLEGPMYAVGG---------HDGWSYLNTVERWDPQARQWNYVANMSNPRSTVGVAVLNGKLYAVGGRDGSSCLRSVECFDPHTNKWTACAPMCKRRGGVGVSACNGFLYAVGGHDTPASNHCSRISDCVERFDPKTDAWTAVAPLSVSRDAVGVGLLGDRLYAVGGYDGQTYLNTVEAYDPVANEWTQVAPLCLGRAGACVVTVR 584 HSP 2 Score: 65.0846 bits (157), Expect = 3.253e-11 Identity = 33/96 (34.38%), Postives = 51/96 (53.12%), Query Frame = 1
Query: 1930 IYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQF 2217
++A+GG D+ S+ERYD N W VA + R G V + K++V GG DG + L +VE Y+ T+TW+ + M + G V + P +
Sbjct: 299 MFAVGGMDATKGATSIERYDLRTNTWTQVAMLSGRRLQFGVAVLDDKVYVVGGRDGLKTLNTVECYNPRTHTWSVLPPMSTHRHGLGVAVLEGPMY 394
BLAST of Kelch-like ECH-associated protein vs. Ensembl Sea Lamprey
Match: klhl8 (kelch-like family member 8 [Source:ZFIN;Acc:ZDB-GENE-070209-226]) HSP 1 Score: 309.301 bits (791), Expect = 8.805e-96 Identity = 179/565 (31.68%), Postives = 284/565 (50.27%), Query Frame = 1
Query: 559 NSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHG--ISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESV--LEDLLQHKK---------INSPHRTAGFNQVLYSAGGYYRHSLA----TFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVG-IVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLL 2199
++ LF +L D+T+KVG + PCH+VVLA A YFR MF S M E E+ + + + ++ F Y G + V LL AA +LQ+ +V AC ++++ SN +G+ FA + KKL A F +NF + +EFL + P L+ + +L+V EV+V+ + +RW + + +L I VR +P F+ + L N R L+ +QH+ +P ++A VL+ GG R S+ + ECY TG W +++ + R + SV G+VY +GG + +E ++ +DP TN W A M+ R +A+ + IYA+GG L + +V E++D + W+ V MN R G+G + R +YAVGG +G+ L +VERY+P D WE V + + R+GAGV L++ +Y +GG+D L SVE+YDP K++W VA + PR +G GKI+ GG++G+ +L +VE YD TN W + + ++G V +
Sbjct: 42 QALLALFEKEQLCDVTIKVGAKRIPCHRVVLASAVPYFRDMFLSDMLETRQGEVSLQDQQLEEGAVEAIVRFAYEGRARLAPDGVQALLYAACILQVEVLVGACSTYMQRNLDASNCLGVRAFAEMHNLKKLMSAADDFTRENFGAVAVAEEFLDVSPSHLVALLSSCDLSVVGEVQVYEATMRWLRRNSQHHERWLPTIAEQVRFPLLPLDFLMRTAFREELLKRNIRCRDLLDEAKNFHLHMQHQDELTEFEFSVRTTPRKSAAGEGVLFCVGG--RGSMGDPFRSIECYDLQTGSWFLAAEMNSRRRHVGVISVGGKVYAVGGHDGNEHLT----SMEMFDPLTNKWIPRASMNTKRRGIALAALASGPIYAIGG---LDDSACFQTV------ERYDVAADSWSTVHCMNLPRGGVGAVALGRYIYAVGGNNGQTSLATVERYDPPLDKWEEVKGMKQRRAGAGVTVLNRCLYVVGGFDDNAPLNSVEKYDPQKDRWEEVADLTTPRGGVGVATLIGKIFAVGGHNGSTYLNTVEAYDPLTNKWEAVGSISQCRAGAGVAI 591
BLAST of Kelch-like ECH-associated protein vs. Ensembl Sea Lamprey
Match: KLHL12 (kelch like family member 12 [Source:HGNC Symbol;Acc:HGNC:19360]) HSP 1 Score: 292.352 bits (747), Expect = 3.867e-90 Identity = 180/567 (31.75%), Postives = 281/567 (49.56%), Query Frame = 1
Query: 562 SMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSL------KPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKK-------------INSPHRTAGFNQVLYSAGGY--YRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYD---PQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKM-----DAG 2175
+M L + L D+TL+V FP H++VLA S YF AMFT+ + E + + + G++ + L+ F+YT + + NV ELL AA +LQ+ V +ACCEFLE Q PSN +GI EFA ++ C L + A+ F K+F ++ +EF L +P ++ + IK DE+ E F TN D ++ +L ++ R H+++ F ++ ++L+ KK + P + G N+VL GG+ + + E Y P + W L I R +A S++ RVY++GG + + V+C D + W + APM++ R + D+IY GG H S E++DP+ QW+ + M R G G+ N +++ VGG+DG N L SVER++P +W V+ ++ RSGAGV L+ H+Y +GG+D A L SVE Y+ + W + M PR +GA V G+++ GYDGN L+S+E YD +TW ++ M DAG
Sbjct: 1 AMNALRKSNTLCDVTLRVDEMDFPAHRIVLAACSDYFCAMFTNELSEKDKPCVDLQGLTAATMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIREFAEAHSCMDLQQAAELFSLKHFPDVVYNEEFRLLPLRLLPQP-EVQKLIKCDEIQCPGVKEYFMDRSGATNCDVRVKSRRVLRMIRTNRTACSHHHYVQHMDPKNLFHHNGRLA--------DELIIKKKCHVLYVACGYLVGVAHPMKLIGANEVLLVIGGFGSQQSPIDVVEKYDPKSQDWSLLPSITRKRRYVATVSLNERVYVMGGYDGRSRLS----SVECLDYGADEDGVWYSVAPMNVRRGLAGATTLGDMIYVAGG---------FDGSRRHTSMERYDPNIDQWSMLGDMATAREGAGLVVANGVIFCVGGYDGINILNSVERFDPHTGHWSHVSPMSTKRSGAGVALLNDHVYVVGGFDGAAHLASVESYNIRTDTWSSITSMTTPRCYVGAAVLRGRLYAIAGYDGNSLLSSIECYDPIIDTWEVVSSMGTQRCDAG 545 HSP 2 Score: 124.79 bits (312), Expect = 3.067e-30 Identity = 67/171 (39.18%), Postives = 92/171 (53.80%), Query Frame = 1
Query: 1696 EKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVE--RYNPDEDN-WEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLL 2199
EK+DP S W+ + S+ R + ++N +Y +GG+DG +RL SVE Y DED W VA +N R AG L IY GG+D + + S+ERYDP+ +QW + M R G V G I+ GGYDG L SVE +D T W+ ++ M +SG V L
Sbjct: 284 EKYDPKSQDWSLLPSITRKRRYVATVSLNERVYVMGGYDGRSRLSSVECLDYGADEDGVWYSVAPMNVRRGLAGATTLGDMIYVAGGFDGSRRHTSMERYDPNIDQWSMLGDMATAREGAGLVVANGVIFCVGGYDGINILNSVERFDPHTGHWSHVSPMSTKRSGAGVAL 454 HSP 3 Score: 113.62 bits (283), Expect = 1.246e-26 Identity = 65/204 (31.86%), Postives = 99/204 (48.53%), Query Frame = 1
Query: 1318 FNQVLYSAGGY---YRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVAL 1920
++Y AGG+ RH+ + E Y P +W L D+ TAR G +G ++ +GG + + N V+ +DP T W +PMS R V +++D +Y VGG H S E ++ + W+ + SM R +G A + LYA+ G+DG + L S+E Y+P D WE V+S+ R AGV L
Sbjct: 361 LGDMIYVAGGFDGSRRHT--SMERYDPNIDQWSMLGDMATAREGAGLVVANGVIFCVGGYDGINILN----SVERFDPHTGHWSHVSPMSTKRSGAGVALLNDHVYVVGG---------FDGAAHLASVESYNIRTDTWSSITSMTTPRCYVGAAVLRGRLYAIAGYDGNSLLSSIECYDPIIDTWEVVSSMGTQRCDAGVCVL 549
BLAST of Kelch-like ECH-associated protein vs. Ensembl Sea Lamprey
Match: klhl20 (kelch-like family member 20 [Source:ZFIN;Acc:ZDB-GENE-040426-1935]) HSP 1 Score: 290.812 bits (743), Expect = 5.219e-89 Identity = 184/590 (31.19%), Postives = 292/590 (49.49%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKM--TRSCLESVLEDLL--QHKKI-----NSPHRTAGFNQVLY----SAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGS------VERYNPDEDNWE----FVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQFE 2220
Y +K+ R + ++ L L D+ L VG+ H+VVL+ S YF AMFT + E E+ I + + LI F YT +I + E NV LL AA +LQ+ + + CCEFL++Q PSN +GI FA ++ C+ L A +F NF E+ +EF+ L QL++ I DELNVRSE +V+++VI W ++ R L ++L HVRL + P F+ + + ++ +R ++ LL Q + + P + +VL+ + GG+ ++++ E Y P T +WR ++ + R G+ + +Y +GG + S N V+ YDP+TN W + AP S R V V ++ +YAVGG +S N E++DP +W+ VASM+ R+G+ VA + LYAVGG DG + L + + P W V+ R R G +A+ ++R+VERY P N+++ + P + +G V G++ GG+DG +L ++EVYDA NTW M+ + G V + + Q E
Sbjct: 38 YMSEKHPRITLEAISVLRRHRELCDVVLAVGSRKIYAHRVVLSACSPYFHAMFTGELAESRQTEVSIRDVDETAMELLIDFAYTAQITVEECNVQALLPAACLLQLAEIQDTCCEFLKRQLDPSNCLGIRAFADTHACRDLLRTADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVYSAVIAWVKYNIQERRPQLPQVLQHVRLPLLTPKFLVGTVGTDLLVKSDEACSSRDLVDEAKNYLLLPQERPLMQGPRTKPRKPIRCGEVLFADHGAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVAVLDDLLYAVGGHDGSSYLN----SVERYDPKTNQWSSDVAPTSTCRTSVGVAVLAGFLYAVGGQDGVSCL---------NIVERYDPKENKWSRVASMSTRRLGVAVAVLGGHLYAVGGSDGTSPLNTGLSLVPIWLAQPMLSCWRSLFPLVSPHPRAREGTLRMAV------------CARVRAVERYSPADNRFLTILKTTAPHT-VGLAVVNGQLMAVGGFDGTTYLKTIEVYDAEANTWRLYGGMNYRRLGGGVGVVKMTQCE 601
BLAST of Kelch-like ECH-associated protein vs. Ensembl Nematostella
Match: EDO47170 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMV8]) HSP 1 Score: 374.4 bits (960), Expect = 4.673e-121 Identity = 204/568 (35.92%), Postives = 300/568 (52.82%), Query Frame = 1
Query: 535 DKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVL-------EDLLQHKKINSPHRTAGFNQVLYSAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
D++ ++ ++S+ L L D+ +KVG+ H+VVLA S YFRAMFT M E EI I + +N LI F YT I I E+NV LL AA +LQ+ + E CCEFL++Q PSN +GI FA ++ C+ L A F NF E+ +EFL L QL++ + DELNVRSE +VF +V+ W ++ + R YL IL HVRL + P F+ + + ++ R ++ + LL P + +V+++ GG+ ++++ E Y P T +W+ ++ + R G+ + +Y +GG + S N V+ YDP+TN W + AP S R V V ++D +YAVGG +S N EK+DP +W VA M+ R+G+GVA V+ LYA+GG DG + L +VERY+P + W VAS+ R G +Y +GG D A +L S ERYDP NQW V M RS +G V G++ GG+DG +L ++EV+D TN W M+ + G V + R P
Sbjct: 6 DRHPKQTLDSLEALRQCEELCDVVIKVGSSTIHAHRVVLAACSPYFRAMFTREMAESRQAEITIRDVDESAMNLLITFAYTASITIEETNVQTLLPAACLLQLTEIQEICCEFLKRQLDPSNCLGIRAFADTHSCRDLLRVADLFTQHNFQEVMESEEFLLLPFAQLVDILSSDELNVRSEEQVFYAVMNWMKYNVTERRAYLSHILQHVRLPLLGPKFLVGVVGTDGLIKSDETCRDLVDEAKNYLLLPEQRLLMQGPRTRPRKPTKCTEVIFAVGGWCSGDAISSVERYDPQTSEWKMVATMMKRRCGVGVTVLDNLLYAVGGHDGSSYLN----SVERYDPKTNQWSSEVAPTSTCRTSVGVAVLDGFMYAVGGQDGVSCL---------NIVEKYDPSENRWARVAPMSTRRLGVGVAVVDSFLYAIGGSDGTSPLNTVERYDPSCNKWVSVASMGTRRKHLGAAVFQDKLYVVGGRDDATELSSAERYDPKTNQWSPVVAMNSRRSGVGLAVVNGQLLAVGGFDGTTYLKTIEVFDTLTNQWKMSGGMNYRRLGGGVGVVRLP 560
BLAST of Kelch-like ECH-associated protein vs. Ensembl Nematostella
Match: EDO49628 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFM5]) HSP 1 Score: 361.688 bits (927), Expect = 7.648e-116 Identity = 198/563 (35.17%), Postives = 308/563 (54.71%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINS----PHR-TAGFNQVLYSAGGYYR--HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
Y+ + + + L +L D+T+K G CH+VVLA SAYF +MFT+ M E + I I G+S + +LI+F+YT +I I N+ LL A+ + Q+ VV ACCEF+++ H SN + + +A +GC + A +F F + D FL L P L E + D+LNV++E VF ++++W HD R+ ++ +++S VRL +P ++ ++++ LS N R+ ++ L ++S P + TAG L+S GG + ECY + W + + T R +A S++GRVY IGG + + N V+C+DP+ N+W APM R ++ G++ +IY GG L + +V E++DP++ +W+ V+SM + R G+GVA + LYAVGG DG L SVERYNP W VAS+NR R+G GV + Q++YAIGG+D + L SVERYDP NQW ++A M R +GA +IW GG++G ++L S+E Y+ + W +M ++G V
Sbjct: 11 YEANDLPSQAFTILTQLLEQEKLCDVTIKAGERKIRCHRVVLASCSAYFHSMFTNSMLESSQEVITIQGLSEKSVIQLINFMYTRKITITIDNIESLLTASAVFQLDPVVYACCEFMKRHLHVSNCLEMRAYAELHGCIEFIHFADKFARGCFTTLVSNDMFLKLSPKHLAEIVSGDDLNVKAEEIVFEAILKWVEHDPEKRSEHIADLISQVRLPLLPTDYLINRVEQNSLLSSNMACRNFIDEAKNFKLCPVNVSSFRTQPRKSTAG---TLFSVGGRGKTGEPFQCIECYDWFSDSWFMTARLSTPRRHVAVASLNGRVYAIGGHDGIQHLN----SVECFDPENNTWTDVAPMRTYRRGMSAGVLQGVIYVAGG---LDEATCFETV------ERYDPETDEWSIVSSMLHRRGGVGVAGLEGYLYAVGGNDGTVSLQSVERYNPHTGRWTRVASMNRRRAGVGVAVVGQYLYAIGGFDDSNPLDSVERYDPKTNQWSYIASMSTCRGGVGAGSMGERIWAVGGHNGTQYLGSMESYNPAKDVWEASAQMSTPRAGSGV 557
BLAST of Kelch-like ECH-associated protein vs. Ensembl Nematostella
Match: EDO42382 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1L8]) HSP 1 Score: 351.288 bits (900), Expect = 4.985e-112 Identity = 195/562 (34.70%), Postives = 302/562 (53.74%), Query Frame = 1
Query: 541 YNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCL-ESVLEDLLQHKKI------NSPHRTAGFNQVLYSAGGYYRHSL-ATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLG 2202
+ E SM + L D+ L VG H++VLA S YF AMFTS + E EI + G+ P + L+ F YT I + E NV LL AA++LQ+ V +ACCEFL+ Q HPSN +GI FA + C L E + RF ++F E+ + +EF+ LK ++++ I ++LNV++E +VFN VI W HD R Y+ +L HVRL + + +++ + + ++ + L E++ LL K++ + R +G +L++ GG ++ + ECY P +W ++ + T R+ + V+G +Y +GG + S D V+ Y PQ N W T PM R + V ++ +IYAVGG S NS E++DP + QWT VA+M+ R + V V ++YAVGG+DG + L +VE ++P + W+ VA++ RS AGVV L+ +Y +GG D A L ++ERY+P+ N W +A M RS + E ++ GG DG+ L S+E YD TN W+ + M +S V +
Sbjct: 24 HTEEAFFSMKQMRCNSELCDVVLLVGDRRIYAHRLVLAACSQYFHAMFTSELLESRQKEISLQGLQPDAMELLVEFAYTARIQVSEDNVQALLPAASLLQLESVKDACCEFLKNQLHPSNCLGIRSFADVHVCTDLHESSYRFALQHFVEVSQTEEFMLLKVNEVLDLISSNDLNVKNEEQVFNGVISWVKHDADSRRKYIARLLHHVRLCLLSRECLMMRVETEEMIKGSEECKDLLIEAMKYHLLPEKRMMLECTRSECRRPSGQVPILFAIGGGSLFAIHSECECYDPRIDRWCMITPMSTKRARVGVGVVNGCIYAVGGYDGS----VDLATVEVYCPQDNQWSTVTPMGTRRSCLGVAVISGLIYAVGGYDGASCL---------NSIERYDPLTAQWTSVAAMSTKRRYVRVGVVGGIIYAVGGYDGSSHLNTVECFDPVTNTWKSVANMASRRSSAGVVVLNNMLYVVGGNDGASCLNTMERYNPETNTWTSLAAMSVRRSTHDIAIIESCLYAVGGNDGSSSLNSIEKYDPATNMWSTVVPMSTRRSSVGVTVA 572 HSP 2 Score: 90.1225 bits (222), Expect = 8.413e-19 Identity = 49/163 (30.06%), Postives = 85/163 (52.15%), Query Frame = 1
Query: 1306 RTAGFNQVLYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLL 1791
R ++Y+ GGY S L T EC+ PVT W+ ++++ + RS ++ +Y++GG + + N ++ Y+P+TN+W + A MS+ R + I++ +YAVGG+ S+ NS EK+DP + W+ V M+ R +GV L+
Sbjct: 427 RVGVVGGIIYAVGGYDGSSHLNTVECFDPVTNTWKSVANMASRRSSAGVVVLNNMLYVVGGNDGASCLN----TMERYNPETNTWTSLAAMSVRRSTHDIAIIESCLYAVGGNDGSSSL---------NSIEKYDPATNMWSTVVPMSTRRSSVGVTVAGVLV 576 HSP 3 Score: 54.6842 bits (130), Expect = 1.021e-7 Identity = 40/132 (30.30%), Postives = 56/132 (42.42%), Query Frame = 1
Query: 1240 TRSCLESVLEDLLQHKKINSPHRTAG---FNQVLYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDII 1623
T C + V + S +AG N +LY GG S L T E Y+P T W L+ + RS + +Y +GG + S N ++ YDP TN W T PMS R V V + ++
Sbjct: 449 TVECFDPVTNTWKSVANMASRRSSAGVVVLNNMLYVVGGNDGASCLNTMERYNPETNTWTSLAAMSVRRSTHDIAIIESCLYAVGGNDGSSSLN----SIEKYDPATNMWSTVVPMSTRRSSVGVTVAGVLV 576
BLAST of Kelch-like ECH-associated protein vs. Ensembl Nematostella
Match: EDO31299 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYB7]) HSP 1 Score: 350.517 bits (898), Expect = 8.044e-112 Identity = 197/537 (36.69%), Postives = 290/537 (54.00%), Query Frame = 1
Query: 562 SMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQ------IKNCKFLSENKMTRSCLESVLEDLLQHKKIN-SPHRTAGFNQVLYSAGGYYRHSLA-TFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTW 2148
S+ +L L D+ L VG HKVVLA S YFRAMFT GM E + + + + +I F Y+G+I I E NV E+L A +LQ+ V EACCEFL++Q P N +GI FA S+ C +L + + F +F ++ + +EF+ + QL + D+LNV SE V+ +V+ W +D+ R Y E+L +VRL + F+ + I+N + S+ + + L + LQ + P + +QVLY+ GG R + + E + P GKW+ + D+ R G A ++ +Y+ GG +++ V+ +DP TN W M R+ V V IYA+GG M N+AE FDP G+W V+ MN+CR G+G A ++ +YAVGG DG N L +VE+++P+ + W VA +N R GV AL ++YAIGG D + +VERYDPDK++W +V PM PRS G V +G I+V GGYDG +L +VE YD +N W
Sbjct: 46 SLNSLRQQEDLCDMVLVVGGSTISAHKVVLASGSPYFRAMFTGGMSESRQDTVTLQELDEKAMQNMIDFFYSGKIEISELNVQEVLPIACLLQVQSVQEACCEFLKRQLSPENCLGICAFADSHSCTELVKFSDAFARLHFVDVVQSEEFMDVPLKQLSRILVEDDLNVHSEERVYEAVMAWIKYDQDLRQEYAPEVLKYVRLPLLSAEFLMDRVATEDIIRNNRLCSDLLLEATELLLLPRRRLQSQTTRVQPRKAVSSHQVLYAIGGMSRRDASKSGERFDPRQGKWKPIGDMKICRWGAAVGAIGPFLYICGGSDDASRLE----TVERFDPFTNVWVPSVSMDASRNGVGVAAGHGRIYAIGG---------FDGSMPLNTAEFFDPKVGRWIEVSRMNHCRFGVGCAVLDTCVYAVGGSDGTN-LKTVEKFDPETNTWTVVAPMNTARKQVGVAALGGYLYAIGGCDHGTRYDTVERYDPDKDRWTYVCPMSTPRSGCGVGVLDGFIYVVGGYDGTTYLQTVERYDPLSNKW 568 HSP 2 Score: 94.3597 bits (233), Expect = 4.275e-20 Identity = 45/135 (33.33%), Postives = 74/135 (54.81%), Query Frame = 1
Query: 1780 NRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSG 2184
+++LYA+GG + S ER++P + W+ + + R GA V A+ +Y GG D A +L +VER+DP N WV M R+ +G G+I+ GG+DG+ L + E +D W E+++M+ + G
Sbjct: 306 HQVLYAIGGMSRRDASKSGERFDPRQGKWKPIGDMKICRWGAAVGAIGPFLYICGGSDDASRLETVERFDPFTNVWVPSVSMDASRNGVGVAAGHGRIYAIGGFDGSMPLNTAEFFDPKVGRWIEVSRMNHCRFG 440 HSP 3 Score: 78.1814 bits (191), Expect = 4.623e-15 Identity = 43/140 (30.71%), Postives = 68/140 (48.57%), Query Frame = 1
Query: 1312 AGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTP 1731
A + +Y+ GG +L T E + P T W ++ + TAR + ++ G +Y IGG ++ Y+ V+ YDP + W PMS PR VG++D IY VGG + + + E++DP S +W P
Sbjct: 444 AVLDTCVYAVGGSDGTNLKTVEKFDPETNTWTVVAPMNTARKQVGVAALGGYLYAIGGCDHGTRYD----TVERYDPDKDRWTYVCPMSTPRSGCGVGVLDGFIYVVGG---------YDGTTYLQTVERYDPLSNKWHP 570 HSP 4 Score: 53.5286 bits (127), Expect = 2.459e-7 Identity = 31/97 (31.96%), Postives = 45/97 (46.39%), Query Frame = 1
Query: 1912 VALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLG 2202
V+ Q +YAIGG +S ER+DP + +W + M R +++ GG D L +VE +D TN W MDA ++G V G
Sbjct: 303 VSSHQVLYAIGGMSRRDASKSGERFDPRQGKWKPIGDMKICRWGAAVGAIGPFLYICGGSDDASRLETVERFDPFTNVWVPSVSMDASRNGVGVAAG 399
BLAST of Kelch-like ECH-associated protein vs. Ensembl Nematostella
Match: EDO29422 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3P4]) HSP 1 Score: 337.035 bits (863), Expect = 1.773e-106 Identity = 203/583 (34.82%), Postives = 307/583 (52.66%), Query Frame = 1
Query: 499 ELISDTFQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLE-DLLQH---KKINSPHRTAGFNQVLYSAGGY--YRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRL------LYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGK--SGHAVLLGR 2205
E SD ++ K+ + + M L +L D+TL V H++VLA S+YF+AMFT G+ E + + + + L+ F YTG++ I NV ++ A+++ Q++ + +AC EFLE+Q HPSN +GI FA ++ C L +++FI++ F+++ + +EFL L +L + ++LNV E EVF ++I WT HD R L E+L ++RL + PHF+ Q++ + +S + R+ L+ LL KKI+ H LYS G HS+ E Y GK + +S ARSG+ + ++Y +GG + + N V+ Y T W+ APM PR VAVG++ ++YAVGG + +S E +DP S QW V+SM N R + V +N+L LYAVGG DG N L +VERY+P+ + W +VAS+ R G GV L +YA GGYD L + ERY P ++W FVAPM RS G V G+++ GG+DG + +VE +D W + M K +G AV+ GR
Sbjct: 15 ETPSDVVKYEAGSKHGIKALMVMDDLRGRKQLCDVTLCVDERQIVAHRLVLASFSSYFQAMFTGGLVESFEDSVTLRDVDSGAVELLVDFAYTGKLDITTENVQSIMYASSLFQLNAIQKACSEFLERQLHPSNCLGIRSFADAHSCVGLLHASEKFINEYFSDVVKNEEFLLLPQEELAVLLSSEDLNVDCEEEVFVALIAWTKHDVDERKDLLAELLQNIRLPLISPHFLIDQVEKEELISHDIKCRNLLDQAKNFHLLPERAPKKISVVHPRRSLMGALYSVCGMDSTGHSVKIVEQYDFHGGKVKVISPTHVARSGVGIGVLDNKLYAVGGHDGTNYLN----SVESYCMVTKQWRFVAPMCNPRRYVAVGVLGGLLYAVGG---------YDGTTVLDSVEVYDPKSDQWKFVSSMKNKRRHVAVGVLNQLDLCLGYLYAVGGHDGVNYLKTVERYDPETNEWSYVASMGARRGGVGVATLHGCLYATGGYDGTSNLSTSERYYPSDDRWAFVAPMSVCRSGHGVGVAGGRLYALGGHDGVSYRNTVEYFDPKVGEWRMVGSMGMCKAVAGVAVIKGR 584
BLAST of Kelch-like ECH-associated protein vs. Ensembl Medaka
Match: keap1b (kelch like ECH associated protein 1 [Source:NCBI gene;Acc:101160787]) HSP 1 Score: 536.954 bits (1382), Expect = 0.000e+0 Identity = 269/569 (47.28%), Postives = 358/569 (62.92%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTEL-----FPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHK--KINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
Y ++ + M L L +L D+TL+V + F HKVVLA +S FRAMFT+G++E + +PI GI P V+ RLI F YT I +GE V ++ A M Q+ VV+ACC+FL +Q PSN IGI FA GC +L +KA+ +I NF+++ +EF +L CQL+ I RDELNVR E EVF + + W +D R Y+ +L VR H + P+F+++Q+++ L + + L + ++L HK K+N P RT Q++Y+AGGY+R SL+ E Y+P TG W RLSD+ RSGLAAC + G Y +GGRNN+ N D+ +DCY+P N W CAPMS+PR+R+ VG++D +IYAVGGS +HHNS E++DP+ QW VA M RIG+GV +NRLLYAVGGFDG NRL S E YNPD D W +AS+N RSGAGV ALD HIY +GGYD QL +VERYD + + W FVA M RSALG T G+I+V GGYDG+ FL SVE YD +TW E+T M +G+SG V + EP
Sbjct: 25 YTLESHTSAAFAIMNELRLERQLCDVTLRVRYKDLDEVDFVAHKVVLASSSPVFRAMFTNGLKECGIELVPIEGIHPKVMERLIEFAYTASISVGEKCVIHVMNGAVMYQIDSVVKACCDFLVQQLDPSNAIGIANFAEQIGCTELHQKAREYIYMNFSQVATQEEFFNLSQCQLVTLISRDELNVRCESEVFQACVAWVRYDHENRRPYVQALLQAVRCHSLTPNFLQTQLQS---LDWDPQCKDYLAQIFQELTLHKPTKVN-PCRTPKVPQLIYTAGGYFRQSLSYLEAYNPCTGAWLRLSDLQVPRSGLAACVISGLFYAVGGRNNAPDGNMDSNALDCYNPMNNCWCPCAPMSVPRNRIGVGVIDGMIYAVGGSH---------GCIHHNSVERYDPERDQWQLVAPMLTRRIGVGVTVMNRLLYAVGGFDGANRLSSCECYNPDRDEWRTMASMNTVRSGAGVCALDTHIYVLGGYDGTNQLNTVERYDVETDAWSFVASMRHRRSALGVTALCGRIFVLGGYDGSTFLDSVECYDPKEDTWMEVTHMTSGRSGVGVAVTMEP 580
BLAST of Kelch-like ECH-associated protein vs. Ensembl Medaka
Match: keap1a (kelch-like ECH-associated protein 1 [Source:NCBI gene;Acc:101159396]) HSP 1 Score: 420.239 bits (1079), Expect = 8.286e-138 Identity = 221/548 (40.33%), Postives = 319/548 (58.21%), Query Frame = 1
Query: 586 GRLTDITLKVGTEL----FPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYY--RHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREP 2211
G L D+ L V + F H+VVLA S YFRAMFT G +E + E+ + + P V+ RLI F YT I +GE V +L +A QM V +ACC+FL K P+NVIGI FA GC +L + + +++ +F+E+ + DEF SL CQL+E I +D L V E EV+ + W D R YL +L+ V ++ +PP F++ Q+ +C LS+ + L + +D+ K +P R Q++Y AGGY ++SLA+ + P W +L+D+ T SGL AC++ G +Y +GG+N S N ++ + CY+P TN W APM++PR+RV V +VD IYAVGGS + +N+ E++DPDS +W+ ++ M+ R+G GVA LY GG+DG NR +VE+Y D + W +A +N RSG G+ L+ +YAIGGYD QL +VE Y +N W A M RSA G TV++G+I+V GGY+ + FL+SVE Y TNTW +T M G+SG V + EP
Sbjct: 53 GMLCDVLLHVTYKERVVDFKVHRVVLASCSPYFRAMFTRGFKECSASEVTLCDVCPEVVGRLIDFAYTARITVGEKCVLHVLLSAMRFQMEDVAKACCDFLIKHLEPANVIGISRFAEEIGCTELQQHCREYVNTHFSEVTKADEFFSLSHCQLLELISQDSLKVLCESEVYKACTDWVRADMESRAQYLHALLNAVHIYALPPKFLKKQLVSCPILSKANSCKDFLAKIFQDITLRKLTPAPIRG---TQLIYVAGGYQHTQNSLASMVAFDPRRNNWLKLADMETPCSGLGACALFGLMYTVGGKNLSLQNNTESNSLCCYNPMTNQWSQRAPMNMPRNRVGVAVVDGCIYAVGGSQ---------GSVQYNTVERWDPDSNRWSFISPMSVARLGAGVAACGGALYVAGGYDGHNRWNTVEKYQLDTNTWHPLAPMNTIRSGLGLACLNSSLYAIGGYDGQSQLCTVECYSMARNIWEPRASMHHCRSAHGVTVHQGRIYVLGGYNQHGFLSSVECYCPETNTWMYITDMPEGRSGMGVTVTMEP 588
BLAST of Kelch-like ECH-associated protein vs. Ensembl Medaka
Match: klhl20 (kelch like family member 20 [Source:NCBI gene;Acc:101170463]) HSP 1 Score: 366.311 bits (939), Expect = 6.072e-117 Identity = 200/565 (35.40%), Postives = 299/565 (52.92%), Query Frame = 1
Query: 526 YQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKI-----NSPHRTAGFNQVLYSAGGYYR-HSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQT-CAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
Y DK+ R+ + + L L D+ L VG + H+V+L+ S YFRAMFT + E E+ I I + LI F YT ++++ E NV LL AA +LQ+ + EACCEFL++Q PSN +GI FA ++ C++L A +F NF E+ +EF+ L QL++ I DELNVRSE +VFN+V+ W + R L ++L HVRL + P F+ + + + ++ R ++ LL Q + + P + +VL++ GG+ ++++ E Y P T +WR ++ + R G+ + +Y +GG + S N V+ YDP+TN W + AP S R V V ++ +YAVGG +S N E++DP +WT VASM+ R+G+ VA + LYAVGG DG + L +VERYNP E+ W V+ + R G IY++GG D +L S ERY+P NQW V M RS +G V G++ GG+DG +L ++EVYD NTW M+ + G V
Sbjct: 45 YVSDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQVIVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLN----SVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSC---------LNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTVSPMGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVYDPDANTWRLYGGMNYRRLGGGV 596 HSP 2 Score: 69.3218 bits (168), Expect = 7.937e-12 Identity = 51/190 (26.84%), Postives = 76/190 (40.00%), Query Frame = 1
Query: 1330 LYSAGGYYRHS-LATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGG--------------------SATLSTQSAHPSV------------------MHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVN 1782
LY+ GG S L E Y P KW R++ + T R G+A + G +Y +GG + + N V+ Y+PQ N W T +PM R + + D+IY+VGG S ++ S V + + E +DPD+ W MN R+G GV +
Sbjct: 415 LYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLN----TVERYNPQENRWHTVSPMGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVYDPDANTWRLYGGMNYRRLGGGVGVIK 600
BLAST of Kelch-like ECH-associated protein vs. Ensembl Medaka
Match: KLHL12 (kelch like family member 12 [Source:NCBI gene;Acc:101171491]) HSP 1 Score: 352.058 bits (902), Expect = 1.125e-111 Identity = 198/568 (34.86%), Postives = 299/568 (52.64%), Query Frame = 1
Query: 535 DKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQ---HKKINSPHRTA--GFNQVLYSAGGY--YRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYD---PQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGRE 2208
+ + + +N+M +L + L DITL+V FP H++VLA S YF AMFTS + E + I G++ + L+ F+YT +L+ NV ELL AA +LQ+ V ACC+FLE Q PSN +GI +FA ++ C L + A+ F K+F+E+ +++EF+ L ++ + IK DE+ V SE VF +V+ W H+R R YL ++L VR+ + P +I I + + R ++ + L+ ++ P A G +VL GG+ + + E Y P T +W L +I R +A S+H RVY+IGG + + V+C D + W T A M++ R + D+IY GG H S E++DP+ QW+ + M R G G+ + L+Y +GG+DG N L SVERY+P +W V + RSGAGV L+ HIY +GG+D L SVE Y+ + W VA M PR +GATV G+++ GYDGN L+S+E YD ++W +T M + V + RE
Sbjct: 43 NSHAKSILNAMNSLRKSNTLCDITLRVENTDFPAHRIVLAACSDYFCAMFTSELAEKGKSFVDIQGLTASTMEILLDFVYTETVLVTVENVQELLPAACLLQLKGVKRACCDFLESQLDPSNCLGIRDFAETHNCLDLMQAAELFSQKHFSEVVQHEEFMLLSQTEVEKLIKCDEIQVDSEEPVFEAVLNWVKHNRKEREPYLPDMLEFVRMPLLTPRYITDVIDAEPLIRCSLPCRDLVDEAKKFHLRPELRSEMQGPRTQARLGAKEVLLVIGGFGSQQSPIDIVEKYDPKTQEWSFLPNIARKRRYVATVSLHDRVYVIGGYDGRSRLS----SVECLDYTADEDGVWYTVATMNVRRGLAGATTLGDMIYVAGG---------FDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGLIYCLGGYDGLNILNSVERYDPHTGHWTSVTPMATKRSGAGVALLNDHIYVVGGFDGISHLDSVEVYNIRTDYWTTVASMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPVVDSWEVVTSMATQRCDAGVCVLRE 597
BLAST of Kelch-like ECH-associated protein vs. Ensembl Medaka
Match: KLHL12 (kelch like family member 12 [Source:NCBI gene;Acc:101171491]) HSP 1 Score: 332.798 bits (852), Expect = 8.848e-105 Identity = 192/566 (33.92%), Postives = 293/566 (51.77%), Query Frame = 1
Query: 535 DKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQ---HKKINSPHRTA--GFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYD---PQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGRE 2208
+ + + +N+M +L + L DITL+V FP H++VLA S YF AMFTS + E + I G++ + L+ F+YT +L+ NV ELL AA +LQ+ V ACC+FLE Q PSN +GI +FA ++ C L + A+ F K+F+E+ +++EF+ L ++ + IK DE+ V SE VF +V+ W H+R R YL ++L VR+ + P +I I + + R ++ + L+ ++ P A G+N + GG R+ + + +I R +A S+H RVY+IGG + + V+C D + W T A M++ R + D+IY GG H S E++DP+ QW+ + M R G G+ + L+Y +GG+DG N L SVERY+P +W V + RSGAGV L+ HIY +GG+D L SVE Y+ + W VA M PR +GATV G+++ GYDGN L+S+E YD ++W +T M + V + RE
Sbjct: 9 NSHAKSILNAMNSLRKSNTLCDITLRVENTDFPAHRIVLAACSDYFCAMFTSELAEKGKSFVDIQGLTASTMEILLDFVYTETVLVTVENVQELLPAACLLQLKGVKRACCDFLESQLDPSNCLGIRDFAETHNCLDLMQAAELFSQKHFSEVVQHEEFMLLSQTEVEKLIKCDEIQVDSEEPVFEAVLNWVKHNRKEREPYLPDMLEFVRMPLLTPRYITDVIDAEPLIRCSLPCRDLVDEAKKFHLRPELRSEMQGPRTQARLGWNPSCWLLGG-LRNMIPKL-----------KNGNIARKRRYVATVSLHDRVYVIGGYDGRSRLS----SVECLDYTADEDGVWYTVATMNVRRGLAGATTLGDMIYVAGG---------FDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGLIYCLGGYDGLNILNSVERYDPHTGHWTSVTPMATKRSGAGVALLNDHIYVVGGFDGISHLDSVEVYNIRTDYWTTVASMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPVVDSWEVVTSMATQRCDAGVCVLRE 549
BLAST of Kelch-like ECH-associated protein vs. Planmine SMEST
Match: SMESG000008374.1 (SMESG000008374.1) HSP 1 Score: 1303.12 bits (3371), Expect = 0.000e+0 Identity = 619/619 (100.00%), Postives = 619/619 (100.00%), Query Frame = 1
Query: 367 MSDNIEDYPVTPLHSQNVIDSRIRSEEFTLNTVSGSGFLCNPTAELISDTFQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQFED 2223
MSDNIEDYPVTPLHSQNVIDSRIRSEEFTLNTVSGSGFLCNPTAELISDTFQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQFED
Sbjct: 1 MSDNIEDYPVTPLHSQNVIDSRIRSEEFTLNTVSGSGFLCNPTAELISDTFQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLLGREPQFED 619
BLAST of Kelch-like ECH-associated protein vs. Planmine SMEST
Match: SMESG000012968.1 (SMESG000012968.1) HSP 1 Score: 330.487 bits (846), Expect = 5.438e-103 Identity = 192/547 (35.10%), Postives = 302/547 (55.21%), Query Frame = 1
Query: 592 LTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVL-------EDLLQHKKINSPHRTAGFN-QVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENR--LGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEM-TKMDAGKSGHAVLL 2199
L D+ LK G HKV+LA S YF AMF+ M E + ++ ++ + +LI+FIYT EI + E NV LL A +LQ++ V +ACCEFL+ Q HPSN +GI FA + CK+L ++++ + +F EI DEF++L L I + L+ + E EVF +V +W H+ + R Y ++ +HVR + F+ K+ +F+ N+ + L L E+ +++ +++ R N ++L GG ++ + E Y T +WR+++++P+ R A G +Y+IGG N S V+ YDP + W++ + M R + V ++D ++YAVGG +SAE +DP++ W +ASM+ R +GVA +N LLY VGG+DG +R L SVE Y+P +D W + +++ RSGA V LD ++YAIGG+D +VERY P+ ++W VA M R G + G ++V GG DG+ L+S+E Y+ TNTWT + + M G+S AV+L
Sbjct: 97 LCDVVLKAGDLEINAHKVILASCSPYFHAMFSGNMCESKAPCVYLNDVNGEALQQLINFIYTCEIHVTEENVQTLLPTANLLQLNEVKDACCEFLQYQLHPSNCLGIHRFADLHSCKELLLYSKQYSETHFCEILNQDEFVNLPVDHLESLISSNNLSAKEE-EVFEAVRKWIKHNLNNRLQYTQKLFAHVRFPLLSKEFLVKLSKDDEFIKTNEACKDFLIYGLRFHLLSSEEKNRNESLHTTPRIPAINPKILMVIGGQAPKAVKSVEEYDFKTEQWRQVTELPSRRCRCGAVLNKGLIYIIGGFNGS----LRVRTVETYDPIKDKWESVSQMEARRSTLGVAVLDGLVYAVGG---------FDGAQGLSSAEVYDPNTDTWRNIASMSLRRSSVGVAVLNGLLYVVGGYDGMDRECLSSVECYSPKKDTWTSITNMSCKRSGAAVGTLDGYLYAIGGHDGPNIRNTVERYSPETDKWSLVAKMNYNRRNAGVVTHNGTLYVVGGDDGSSNLSSIEYYNPLTNTWTLLNSNMMIGRSYAAVVL 629
BLAST of Kelch-like ECH-associated protein vs. Planmine SMEST
Match: SMESG000078467.1 (SMESG000078467.1) HSP 1 Score: 286.189 bits (731), Expect = 5.476e-84 Identity = 190/575 (33.04%), Postives = 283/575 (49.22%), Query Frame = 1
Query: 478 FLCNPTAEL----ISDTFQHYQIDKYNRECMNSMYTLFLAGRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEI-GRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKN---------CK-FLSENKM--TRSCLESVLEDLLQHKKINSPHRTAGFNQVLYSAGGY--YRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQ-----LRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYD 2130
FLC L ++D Q Y + Y + + L RL D+ LKV + FP HK+VLA AS +F AMF+ GM E I + IS +IN ++ ++YTG I++ NV ELL AA + Q+ + +ACC +L +Q PSNV+GI FA + C L + A++F N + + +EF+ L +L + IK +LN+ +E V+N+VIRW + + R +L +L+ VRL Q+ F+ I N C+ + E K+ R L S L H++ S + A N L GG+ + +++ E + P + +W L +P +AACS+ +Y+IGG + E N T V + W A M R A + + I+ GG + S E +DP QW+ SM R G G+ V+ LY VGG++G L +VE+Y+ D W ++ RSGAG +++ IY GGY A + L SVE Y+ QW F+ M PR +GA + IWV GYDGN L +VE +D
Sbjct: 3 FLCKIKKHLNNISLNDDIQRYSTNTYGK-----INEFRLQNRLCDVVLKVQDKEFPAHKIVLAAASDFFSAMFSCGMAESEQSVIELKSISIDIINDILEYVYTGNIVVTNENVQELLPAANLTQLIGLKQACCIYLMRQIDPSNVLGIRRFAEIHDCHLLEKFARKFAAHNMEAVLQQSEEFVQLSRSELRQLIKMTDLNIYTEESVYNAVIRWIYYSKETRAKWLPHLLAKVRLSQLSIRFLTDIISNEPLIRESLPCRDLVDEAKLYHLRPDLRSTLMKKSAHERFWSRNDGAS-NHFLVLLGGFGSDQAPISSVEIFDPRSQRWGSLPSLPGRYRYVAACSIASCIYVIGGFDGRERLN--TVSVLDVGNLSQGWMELASMQYKRGLAATCVYNGRIFVCGG---------FDGIARLKSLEVYDPSINQWSRKESMETSREGAGLVVVDSYLYCVGGYNGMQLLDTVEKYDILNDQWSKSEPMHYRRSGAGCAVMNETIYVCGGYGGAIRQGPQHLDSVECYNTLTQQWSFITSMQEPRCYIGACQMDNMIWVAAGYDGNRLLNTVEAHD 560 HSP 2 Score: 96.6709 bits (239), Expect = 2.737e-20 Identity = 52/168 (30.95%), Postives = 81/168 (48.21%), Query Frame = 1
Query: 1687 NSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPD--EDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSG 2184
+S E FDP S +W + S+ + ++ +Y +GGFDG RL +V + W +AS+ R A + I+ GG+D +L+S+E YDP NQW M R G V + ++ GGY+G + L +VE YD + W++ M +SG
Sbjct: 312 SSVEIFDPRSQRWGSLPSLPGRYRYVAACSIASCIYVIGGFDGRERLNTVSVLDVGNLSQGWMELASMQYKRGLAATCVYNGRIFVCGGFDGIARLKSLEVYDPSINQWSRKESMETSREGAGLVVVDSYLYCVGGYNGMQLLDTVEKYDILNDQWSKSEPMHYRRSG 479 HSP 3 Score: 74.3294 bits (181), Expect = 2.135e-13 Identity = 44/143 (30.77%), Postives = 67/143 (46.85%), Query Frame = 1
Query: 1780 NRLLYAVGGFDGENR-LGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDK--NQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVLL 2199
N L +GGF + + SVE ++P W + SL ++ IY IGG+D +L +V D W+ +A M R VY G+I+V GG+DG L S+EVYD N W+ M+ + G +++
Sbjct: 295 NHFLVLLGGFGSDQAPISSVEIFDPRSQRWGSLPSLPGRYRYVAACSIASCIYVIGGFDGRERLNTVSVLDVGNLSQGWMELASMQYKRGLAATCVYNGRIFVCGGFDGIARLKSLEVYDPSINQWSRKESMETSREGAGLVV 437
BLAST of Kelch-like ECH-associated protein vs. Planmine SMEST
Match: SMESG000077860.1 (SMESG000077860.1) HSP 1 Score: 278.87 bits (712), Expect = 7.341e-84 Identity = 161/536 (30.04%), Postives = 262/536 (48.88%), Query Frame = 1
Query: 586 GRLTDITLKVGTELFPCHKVVLAGASAYFRAMFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKINSPH-------RTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKM 2166
G+ D+TL V F HK+VLA + YF MF + M E + I +HG+ P + LI+F Y GE+ I +NV + A LQ+ V ACCEF++ + V+ + FA S C L A +I NF I +EF L L+E I +DEL V +E VF +VIRW + S R YL +++ +R Q+ P ++ + + + + + R+ L++ + L+ Q + PH + + + + G + + E Y P+ +W L + T ++ + + +Y+IGG + S HVD ++ +T W + A M+ R + +++D IY GG + + S E++ P +W + M CR GV +++ LYA+GG +G SVE +NP W+ + + R GV L+Q IYA GGYD L SVE + +QW ++A M PRS + G+I+ GG+DG+ L + E ++A + W EM+++
Sbjct: 57 GKFCDVTLIVDGHQFSAHKIVLAASIPYFNGMFMNDMVESSEKNIKLHGLDPNSLEALINFAYRGEVYITPNNVQSIFMGANFLQISSVRVACCEFMKNRISSQTVLPLRTFAKSLFCHDLLHAADIYIYNNFMSIINLNEFFDLSFEDLLEIICKDELQVITEEIVFEAVIRWIEYAISERKHYLADLMKQIRFPQISPEYLLETVCSNQIIQNSLQCRNVLDATKDFLILPQQMRNLEPHNFRPRYLQNSLYGFIFVIGGSFQNGNQVNMEVYHPILRQWCSLDQLGTNKTRVGVAVLDHYIYVIGGFDGSR----RLSHVDVFNTKTMKWSSVANMNCNRSALGATMMNDKIYVCGG---------YDGTIALKSCEEYCPKLNRWRVIPPMLECRSATGVVHLSQKLYAIGGHNGLAIDNSVECFNPVMKCWDLITPMLNRRCRHGVAVLNQSIYAAGGYDGVNFLSSVEVFSVTTSQWTYIASMKVPRSRMSLISTFGEIFAIGGFDGSGNLKTTECFNARSQQWLEMSRL 579 HSP 2 Score: 113.62 bits (283), Expect = 5.978e-26 Identity = 60/191 (31.41%), Postives = 90/191 (47.12%), Query Frame = 1
Query: 1621 IYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
I+ +GGS Q + E + P QW + + + +GVA ++ +Y +GGFDG RL V+ +N W VA++N RS G ++ IY GGYD L+S E Y P N+W + PM+ RSA G K++ GG++G SVE ++ W +T M + H V
Sbjct: 313 IFVIGGSFQNGNQV---------NMEVYHPILRQWCSLDQLGTNKTRVGVAVLDHYIYVIGGFDGSRRLSHVDVFNTKTMKWSSVANMNCNRSALGATMMNDKIYVCGGYDGTIALKSCEEYCPKLNRWRVIPPMLECRSATGVVHLSQKLYAIGGHNGLAIDNSVECFNPVMKCWDLITPMLNRRCRHGV 494 HSP 3 Score: 82.4185 bits (202), Expect = 5.272e-16 Identity = 49/138 (35.51%), Postives = 73/138 (52.90%), Query Frame = 1
Query: 1786 LLYAVGG-FDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVL 2196
++ +GG F N++ ++E Y+P W + L ++ GV LD +IY IGG+D + +L V+ ++ +W VA M RSALGAT+ KI+V GGYDG L S E Y N W + M +S V+
Sbjct: 312 FIFVIGGSFQNGNQV-NMEVYHPILRQWCSLDQLGTNKTRVGVAVLDHYIYVIGGFDGSRRLSHVDVFNTKTMKWSSVANMNCNRSALGATMMNDKIYVCGGYDGTIALKSCEEYCPKLNRWRVIPPMLECRSATGVV 448
BLAST of Kelch-like ECH-associated protein vs. Planmine SMEST
Match: SMESG000077860.1 (SMESG000077860.1) HSP 1 Score: 252.677 bits (644), Expect = 4.850e-75 Identity = 148/505 (29.31%), Postives = 245/505 (48.51%), Query Frame = 1
Query: 679 MFTSGMREVNMHEIPIHGISPMVINRLIHFIYTGEILIGESNVCELLAAATMLQMHHVVEACCEFLEKQFHPSNVIGIFEFASSNGCKKLAEKAQRFIDKNFNEIGRYDEFLSLKPCQLMEFIKRDELNVRSEVEVFNSVIRWTNHDRSYRTIYLLEILSHVRLHQMPPHFIRSQIKNCKFLSENKMTRSCLESVLEDLL--QHKKINSPH-------RTAGFNQVLYSAGGYYRHSLATFECYSPVTGKWRRLSDIPTARSGLAACSVHGRVYLIGGRNNSELYNFDTPHVDCYDPQTNSWQTCAPMSIPRHRVAVGIVDDIIYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKM 2166
MF + M E + I +HG+ P + LI+F Y GE+ I +NV + A LQ+ V ACCEF++ + V+ + FA S C L A +I NF I +EF L L+E I +DEL V +E VF +VIRW + S R YL +++ +R Q+ P ++ + + + + + R+ L++ + L+ Q + PH + + + + G + + E Y P+ +W L + T ++ + + +Y+IGG + S HVD ++ +T W + A M+ R + +++D IY GG + + S E++ P +W + M CR GV +++ LYA+GG +G SVE +NP W+ + + R GV L+Q IYA GGYD L SVE + +QW ++A M PRS + G+I+ GG+DG+ L + E ++A + W EM+++
Sbjct: 1 MFMNDMVESSEKNIKLHGLDPNSLEALINFAYRGEVYITPNNVQSIFMGANFLQISSVRVACCEFMKNRISSQTVLPLRTFAKSLFCHDLLHAADIYIYNNFMSIINLNEFFDLSFEDLLEIICKDELQVITEEIVFEAVIRWIEYAISERKHYLADLMKQIRFPQISPEYLLETVCSNQIIQNSLQCRNVLDATKDFLILPQQMRNLEPHNFRPRYLQNSLYGFIFVIGGSFQNGNQVNMEVYHPILRQWCSLDQLGTNKTRVGVAVLDHYIYVIGGFDGSR----RLSHVDVFNTKTMKWSSVANMNCNRSALGATMMNDKIYVCGG---------YDGTIALKSCEEYCPKLNRWRVIPPMLECRSATGVVHLSQKLYAIGGHNGLAIDNSVECFNPVMKCWDLITPMLNRRCRHGVAVLNQSIYAAGGYDGVNFLSSVEVFSVTTSQWTYIASMKVPRSRMSLISTFGEIFAIGGFDGSGNLKTTECFNARSQQWLEMSRL 492 HSP 2 Score: 114.39 bits (285), Expect = 2.288e-26 Identity = 60/191 (31.41%), Postives = 90/191 (47.12%), Query Frame = 1
Query: 1621 IYAVGGSATLSTQSAHPSVMHHNSAEKFDPDSGQWTPVASMNNCRIGLGVATVNRLLYAVGGFDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAV 2193
I+ +GGS Q + E + P QW + + + +GVA ++ +Y +GGFDG RL V+ +N W VA++N RS G ++ IY GGYD L+S E Y P N+W + PM+ RSA G K++ GG++G SVE ++ W +T M + H V
Sbjct: 226 IFVIGGSFQNGNQV---------NMEVYHPILRQWCSLDQLGTNKTRVGVAVLDHYIYVIGGFDGSRRLSHVDVFNTKTMKWSSVANMNCNRSALGATMMNDKIYVCGGYDGTIALKSCEEYCPKLNRWRVIPPMLECRSATGVVHLSQKLYAIGGHNGLAIDNSVECFNPVMKCWDLITPMLNRRCRHGV 407 HSP 3 Score: 82.8037 bits (203), Expect = 2.989e-16 Identity = 49/138 (35.51%), Postives = 73/138 (52.90%), Query Frame = 1
Query: 1786 LLYAVGG-FDGENRLGSVERYNPDEDNWEFVASLNRTRSGAGVVALDQHIYAIGGYDSACQLRSVERYDPDKNQWVFVAPMIRPRSALGATVYEGKIWVFGGYDGNEFLTSVEVYDAGTNTWTEMTKMDAGKSGHAVL 2196
++ +GG F N++ ++E Y+P W + L ++ GV LD +IY IGG+D + +L V+ ++ +W VA M RSALGAT+ KI+V GGYDG L S E Y N W + M +S V+
Sbjct: 225 FIFVIGGSFQNGNQV-NMEVYHPILRQWCSLDQLGTNKTRVGVAVLDHYIYVIGGFDGSRRLSHVDVFNTKTMKWSSVANMNCNRSALGATMMNDKIYVCGGYDGTIALKSCEEYCPKLNRWRVIPPMLECRSATGVV 361 The following BLAST results are available for this feature:
BLAST of Kelch-like ECH-associated protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Kelch-like ECH-associated protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Kelch-like ECH-associated protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30023314 ID=SMED30023314|Name=Kelch-like ECH-associated protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2274bpback to top protein sequence of SMED30023314-orf-1 >SMED30023314-orf-1 ID=SMED30023314-orf-1|Name=SMED30023314-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=620bp MSDNIEDYPVTPLHSQNVIDSRIRSEEFTLNTVSGSGFLCNPTAELISDTback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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