TNF receptor-associated factor-2-like protein B

Overview
NameTNF receptor-associated factor-2-like protein B
Smed IDSMED30023307
Length (bp)1339
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TNF receptor-associated factor-2-like protein B (SMED30023307) t-SNE clustered cells

Violin plots show distribution of expression levels for TNF receptor-associated factor-2-like protein B (SMED30023307) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TNF receptor-associated factor-2-like protein B (SMED30023307) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TNF receptor-associated factor-2-like protein B (SMED30023307) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023307

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30023307h1SMcG0005642 Contig4033GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
pigment cellSMED30023307h1SMcG0005642 SmedASXL_012229SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult RNA-sequencing evidence
gutSMED30023307h1SMcG0005642 dd_Smed_v4_1308_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30023307h1SMcG0005642 dd_Smed_v4_1308_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023307h1SMcG0005642 Contig35624uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023307h1SMcG0005642 Contig35624newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023307h1SMcG0005642 Contig42632newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023307h1SMcG0005642 Contig42632uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
tail regionSMED30023307h1SMcG0005642 dd_Smed_v6_1308_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
gutSMED30023307h1SMcG0005642 SMED30023307smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30023307h1SMcG0005642 SMED30023307smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30023307h1SMcG0005642 dd_Smed_v6_1308_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30023307h1SMcG0005642 Contig4033GPL15192PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 69.3218 bits (168), Expect = 5.041e-12
Identity = 91/394 (23.10%), Postives = 166/394 (42.13%), Query Frame = 1 
Query:   97 TENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEE-----------CKQQFLTNLQIDYKANNR--VQKLIV----------------KCPEKTCLYKCKLSNMDNHL-RFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQM-------KQSIEMLAHHEE--IH-EENITSLKNSLKEKENQI----------ESLKREVEILTNKINE--KVDQNA--LTLNAILLEMS-KDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
             + + +  KC  C  +L +  Q+ CG  FC+ C+   + +    C    E            CK++ L  LQI  +  +R   ++L++                 C    C  K    ++ +H+ + C  +   C +       +A+     +  +Q+E    N  I  ++NQ+       ++  EML ++E   +H +  I S    LKE + +I          +S+K  VE L N++ E   VD++A  +  N  LLE      DQ L  +++ +  ++   R  +L    +   Y+        G ++W I    + ++     K  S+ S+ FY GY  YKM   +Y NG G   G+ LS++  I      + + WPFK  VT+ ++++
Sbjct:   44 VKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILA-LQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQ----VSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQML--SVHDIRLADMDLRFQVL----ETASYN--------GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ 418
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Human
Match: TRAF2 (TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032])

HSP 1 Score: 64.3142 bits (155), Expect = 1.912e-10
Identity = 69/296 (23.31%), Postives = 122/296 (41.22%), Query Frame = 1 
Query:  229 CPGKSEECKQQFLTNLQIDYKANNRV-QKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKG-----GSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            CP +S  C+         D KA++ V  K  + C +     K       +H++ C K  V C ++ +GC E  +  +K  +H    +  H +M+L    + K  +   +H      +   SL+      EN +  L REVE +         Q+ L  + I    SK   Q+L+++I   + +     + +L          E    +  G  +W I    + R++       ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L++
Sbjct:  156 CPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTC-DGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLET-VEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKV--QQLERSIGLKDLAMADLEQKVL----------EMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ 437
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 64.3142 bits (155), Expect = 2.287e-10
Identity = 77/316 (24.37%), Postives = 133/316 (42.09%), Query Frame = 1 
Query:  313 LIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGC------------------------DEVAIATDKVIDHIQSEIYSHNSMILGINNQM-------KQSIEMLAHHEE--IH-EENITSLKNSLKEKENQI----------ESLKREVEILTNKINE--KVDQNA--LTLNAILLEMS-KDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            ++V CP K  +     S +  HL  C      C +   GC                         E + + +K +  +Q+E    N  I  ++NQ+       ++  EML ++E   +H +  I S    LKE + +I          +S+K  VE L N++ E   VD++A  +  N  LLE      DQ L  +++ +  ++   R  +L    +   Y+        G ++W I    + ++     K  S+ S+ FY GY  YKM   +Y NG G   G+ LS++  I      + + WPFK  VT+ ++++
Sbjct:  200 VVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQML--SVHDIRLADMDLRFQVL----ETASYN--------GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ 501
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 64.3142 bits (155), Expect = 2.287e-10
Identity = 77/316 (24.37%), Postives = 133/316 (42.09%), Query Frame = 1 
Query:  313 LIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGC------------------------DEVAIATDKVIDHIQSEIYSHNSMILGINNQM-------KQSIEMLAHHEE--IH-EENITSLKNSLKEKENQI----------ESLKREVEILTNKINE--KVDQNA--LTLNAILLEMS-KDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            ++V CP K  +     S +  HL  C      C +   GC                         E + + +K +  +Q+E    N  I  ++NQ+       ++  EML ++E   +H +  I S    LKE + +I          +S+K  VE L N++ E   VD++A  +  N  LLE      DQ L  +++ +  ++   R  +L    +   Y+        G ++W I    + ++     K  S+ S+ FY GY  YKM   +Y NG G   G+ LS++  I      + + WPFK  VT+ ++++
Sbjct:  200 VVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQML--SVHDIRLADMDLRFQVL----ETASYN--------GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ 501
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035])

HSP 1 Score: 62.3882 bits (150), Expect = 7.794e-10
Identity = 92/383 (24.02%), Postives = 150/383 (39.16%), Query Frame = 1 
Query:  139 KILMNAYQ--------SPCGCSFCQKCIEEFIQNEPK-----LCPGKSEEC----KQQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDK---VIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIES---------------------------LKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLK------QAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGS-----ILWSIE--KINKCRKKGG---SVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            K+++  YQ         P  CS  +KC E  ++ + K      C  + E+C    K   + NLQ      N   +  V CP   C      + +D HL  C +    CP+   GC      TDK   +  H  S +  H  ++L  N Q+++ I  L    E  E  I  L  ++K+ E + +                            L+ +V  L   +N++  QN   L   L+E      QK+       Q +  + E   K+   I +      K +EE F  + G+     ++W +   K+ K     G   S+ S+ FY     Y++    Y NG G+  GS LS+Y  +      S + WPF+  VT+ +L++
Sbjct:  119 KVILGRYQDHLQQCLFQPVQCSN-EKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQ--NHEENLCPEYPVFCP-NNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGC----AVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQ--QNKFDLRP-LMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSK-NEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ 489
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345])

HSP 1 Score: 65.855 bits (159), Expect = 4.401e-11
Identity = 56/255 (21.96%), Postives = 107/255 (41.96%), Query Frame = 1 
Query:  376 HLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEE---------IHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            H + C+K    C + ++GC  V +   K  +H Q+ I  H  ++L + + M+   E     +E           +       N  +     ++     +E +   +N++V+++ALT+ AI  +   D  +K++     V +         L          E  F +  G  +W I + ++ R+     +  ++ S  FY     YKM L +Y NG G   GS LS++  +      + + WPF   VT+ +L++
Sbjct:  216 HTKSCAKSKSACQFREIGCRAV-VDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLD-QEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ 468
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345])

HSP 1 Score: 65.855 bits (159), Expect = 4.401e-11
Identity = 56/255 (21.96%), Postives = 107/255 (41.96%), Query Frame = 1 
Query:  376 HLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEE---------IHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            H + C+K    C + ++GC  V +   K  +H Q+ I  H  ++L + + M+   E     +E           +       N  +     ++     +E +   +N++V+++ALT+ AI  +   D  +K++     V +         L          E  F +  G  +W I + ++ R+     +  ++ S  FY     YKM L +Y NG G   GS LS++  +      + + WPF   VT+ +L++
Sbjct:  216 HTKSCAKSKSACQFREIGCRAV-VDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLD-QEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ 468
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345])

HSP 1 Score: 65.855 bits (159), Expect = 4.568e-11
Identity = 56/255 (21.96%), Postives = 107/255 (41.96%), Query Frame = 1 
Query:  376 HLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEE---------IHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            H + C+K    C + ++GC  V +   K  +H Q+ I  H  ++L + + M+   E     +E           +       N  +     ++     +E +   +N++V+++ALT+ AI  +   D  +K++     V +         L          E  F +  G  +W I + ++ R+     +  ++ S  FY     YKM L +Y NG G   GS LS++  +      + + WPF   VT+ +L++
Sbjct:  229 HTKSCAKSKSACQFREIGCRAV-VDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLD-QEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ 481
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Zebrafish
Match: traf5 (Tnf receptor-associated factor 5 [Source:ZFIN;Acc:ZDB-GENE-071120-3])

HSP 1 Score: 58.151 bits (139), Expect = 4.164e-9
Identity = 50/239 (20.92%), Postives = 113/239 (47.28%), Query Frame = 1 
Query:  589 LKNSLKEKENQIESLKREVE---ILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRK--DI----------LLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCII--DNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNE 1254
            ++ S++E+  +I S++RE+    +L +++ E++ +   +L+++  +++    + L++ + ++ ++ E++ +  DI           LR  +   YD        G ++W +      ++ G ++ S  FY   + YK+ +  Y  G G+  GS +S+YI I      S + WPF+  +T+ +L++  T   +  +    +  D+F     DA  +      I  CD +      F+ +E
Sbjct:   17 VQRSVEEQRVRICSVQRELRDLRVLGSELKEELPRLQASLDSLRQQVA--VTESLREHLGALEQTCERHTRLLDIHVEQLQCNEQRLRQLESSSYD--------GKLIWKVRDYWHRKESGAALSSSPFYTSRSGYKLSVRAYLGGDGSGRGSHMSLYITIMRGDFDSFLPWPFRQNITLTLLDQSGTRNHMSHTFIPDVNSDSFHRPTSDANVATGFTRFISHCDLENPRNAVFVRDE 245
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Zebrafish
Match: traf2a (Tnf receptor-associated factor 2a [Source:ZFIN;Acc:ZDB-GENE-071120-2])

HSP 1 Score: 59.6918 bits (143), Expect = 4.235e-9
Identity = 68/314 (21.66%), Postives = 128/314 (40.76%), Query Frame = 1 
Query:  373 NHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSM----ILGINNQMK----QSIEMLAH-----HEEIHE--------------------------------ENITSLKNSL---------KEKENQIESLKR--EVEILTNK-------INEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLR----FNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            +H++ C+K    C ++ +GCD + +  +K+ DH Q+  Y H ++    I+GI   ++    QS+E+ +H     H+ + E                                 + T L  ++          EK   +E  +R  E+E+  N        +N +++++A T+ A   +   D D+     I  +N    +  + + LR         K  E    +  G  +W I   +K R+     +  ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L++
Sbjct:  204 DHIKLCTKFRTPCRFHVVGCD-MTVEKEKIHDHEQACSYEHLNLLLHFIMGIKVNLESLQPQSLELASHKIHELHQSLRELELKMGQLCGAGASVQGACALPPPPPPAPTLGTSFTPLPTAVGAALELQLHSEKTKVVELSRRCQELELKVNTFENIVCVLNREMERSATTMEAYNRQHRLDQDK-----IEILNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ 511
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925])

HSP 1 Score: 74.3294 bits (181), Expect = 1.166e-13
Identity = 87/370 (23.51%), Postives = 161/370 (43.51%), Query Frame = 1 
Query:  139 KILMNAYQSPCG-----CSFCQK--CIEEFIQNEPKL-----CPGKSEECK--QQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLK--EKE------------NQIESLKREVEILTNK--INEKVDQ------NALTLNAIL--LEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKY--DEEHFDSVAGS-----ILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            K+++  YQ   G      + C    C ++ I+ E K      C  + E C   +Q + ++ +        Q   V CP   C   C  + +D HL  C +  ++C + + GC+ V +   KV +H  + +  H   +L  N ++++ +  L  + ++ E  I  L +++K  EKE            N + S K     +     + E+V Q      + L L  IL  LE +K     L+     ++  + +++K  +L  N   +   +EE F  V G+     ++W I    + ++     +  S+ S++FY  +  Y++    Y NG G+  GS LS+Y  +      S + WPFK  VT+ +L++
Sbjct:   51 KVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMASINLTIHVGLYCQLYPVPCP-NACPVTCPRAELDKHLCECPEAELQCTFSNYGCN-VMVKRGKVKEHEDTFLRDHMLYVLNRNMKLEEQVLGLQQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQ 418
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925])

HSP 1 Score: 70.0922 bits (170), Expect = 2.775e-12
Identity = 106/465 (22.80%), Postives = 185/465 (39.78%), Query Frame = 1 
Query:   10 LCKFLLDLMSHSEKLDSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQ-NEPKLCP-----GKSEE------CKQQFLTNL-------QIDYKAN-NRVQKLIVKC-------------------------------PEKTCLYKCKLSNMDNH--------LRF-CSKKSVKCPYYDLGCD------EVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLK--EKE------------NQIESLKREVEILTNK--INEKVDQ------NALTLNAIL--LEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKY--DEEHFDSVAGS-----ILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            LC   + L   +       + + K ++   E + +  KC  C  +L N +Q+ CG  FC+KCI   I+ +E   CP      KS E      CK++ L  L         D K    R Q+ + +C                                ++ C+Y CK +   NH          F   K   +CP  +L C        V +   KV +H  + +  H   +L  N ++++ +  +  + ++ E  I  L +++K  EKE            N + S K     +     + E+V Q      + L L  IL  LE +K     L+     ++  + +++K  +L  N   +   +EE F  V G+     ++W I    + ++     +  S+ S++FY  +  Y++    Y NG G+  GS LS+Y  +      S + WPFK  VT+ +L++
Sbjct:    6 LCPLPVTLGRQNSSAAVSLDFVPKQEYLFVEQLQDRYKCASCHLVLHNPHQTGCGHRFCEKCISNLIELSETPQCPIDMENIKSHEIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIY-CKQTMSFNHENNYKKIFFSFQLDKHLCECPEAELQCTFSNYGCNVMVKRGKVKEHEDTFLRDHMLYVLNRNMKLEEQVLSVLQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQ 469
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 62.003 bits (149), Expect = 1.155e-9
Identity = 92/444 (20.72%), Postives = 167/444 (37.61%), Query Frame = 1 
Query:  106 ISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQN-EPK----------------------------LCPGKSEECKQQF-LTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHL-----------RFCSKK----------SVKCPYYDLGCDEV-----------------AIATDKVIDHI-----------------QSEIYSHNSMILGINNQM-KQSIEMLAHHEEIH--EENITSLKNSLKEKENQIESLKREV-----------------EILTNKIN--EKVDQNALTLNAILLEMS-KDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            + E  KC  C  +L N  Q+ CG  FC+ C+   + +  P+                             C  ++  CK+   L NL I  K++ + ++L   CP   C  K    ++ +H+           +FC  +           V CP   + C  +                 A      + H+                 Q+E    N  I  ++NQM    IE+  H E++   E  I  L+  ++ + ++++ L +E+                 E L N+++  E + +NA + N  +LE      DQ L  +++ +  ++   R  +L               S  G ++W I    + ++     K  S+ S+ FY GY  YKM   +Y NG G   G+ LS++  I      + + WPFK  V++ ++++
Sbjct:   42 VEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEEL--SCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSEGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQML--SVHDIRLADMDLRFQVL------------ETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQ 469
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Xenopus
Match: sytl2 (synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-945155])

HSP 1 Score: 59.3066 bits (142), Expect = 6.608e-9
Identity = 91/410 (22.20%), Postives = 161/410 (39.27%), Query Frame = 1 
Query:   85 DFEATENISEDLKCMLCEKILMNAYQ-SPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKC--PEKTCLYKCKLSNMDNHLRF-----------CSKKSVK----------CPYYDLGCDEVA--IATDKVIDH----IQSEIYSHN----SMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQ-------------IESLKREVEILTNKINEKVDQNALTL----------NAILLEMSKDFDQKLKQAIYSVNESNEKYRKDIL-LRFNDPGKYDEEHFDSVAGSILWSI----EKINKCRKKGGSVE-SEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQ 1125
            D++  E +     C LC K +    Q S CG  FC  C++EF+      CP   E+        +  D     +V  L ++C   E+ C +  +L  +  HL             CS K ++          CP   + C+        +   DH     Q  +Y  N     M+  + +Q    +E     +     N   + ++++  + Q             I S+ RE   L+N + +    +AL L              + +S+  ++ ++  +  ++    + R++IL LR     K  EE   S  G ++W I     K+ + + +G     S  FY     YK+++  + NG G+  GS LS+YI + P    + ++WPF   VT  +L++ D   S  Q
Sbjct:    5 DYKFLEKLRRKFLCPLCGKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCP---EDQLPLDYAKIYPDRDLETQVMGLSIRCIHSEEGCRWSGQLKQLQPHLNICAFNVIPCPNRCSTKLIRRDLPEHMQHDCPKRKVRCEFCGADFTGEAYEDHQGCCPQESVYCENKCGARMMRRVLSQ-HSLVECPKRTQPCPYCNKEFVFDTIQSHQYQCPRYPTPCPNQCGIASIARE--DLSNHLKDSCS-SALVLCPFKDSGCKHRGPKITISRHLEENMRAHLSMMSSLVSRQRQEILELR-----KQVEELSVSSEGVLIWKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQSDPSLSKPQ 402
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 58.5362 bits (140), Expect = 1.263e-8
Identity = 69/314 (21.97%), Postives = 128/314 (40.76%), Query Frame = 1 
Query:  313 LIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCD-----------EVAIATDKV-------------IDHIQSEIYSHNSMILGINNQM-KQSIEMLAHHEEIH--EENITSLKNSLKEKENQIESLKREV-----------------EILTNKIN--EKVDQNALTLNAILLEMS-KDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            +++ CP    +     S ++ HL  C      C +   GC            E + A   V             +  +Q+E    N  I  ++NQM    IE+  H E++   E  I  L+  ++ + ++++ L +E+                 E L N+++  E + +NA + N  +LE      DQ L  +++ +  ++   R  +L               S  G ++W I    + ++     K  S+ S+ FY GY  YKM   +Y NG G   G+ LS++  I      + + WPFK  V++ ++++
Sbjct:  195 VVISCPHMCSVKSLLRSELNAHLLECVNAPSTCSFKRYGCTFKGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQML--SVHDIRLADMDLRFQVL------------ETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQ 494
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835])

HSP 1 Score: 66.6254 bits (161), Expect = 2.796e-11
Identity = 68/298 (22.82%), Postives = 122/298 (40.94%), Query Frame = 1 
Query:  229 CPGKSEECKQQFL----TNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLN 1095
            CP +S  C+         +L++ Y+   +       C +K    K       +H+R CSK  V C ++ +GC E+ + T+ + DH    +  H +++L    + + S   L        +    L+  +   EN +  L REVE +         Q+ L  + I     +    K++Q   S+        KD+ +  +   K  E    +  G  +W I    + R+     +  ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L+
Sbjct:  156 CPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTCDGCGKK----KIPRETFQDHVRACSKCRVLCRFHTVGCSEM-VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKI-----EALSNKVQQLERSIG------LKDLAMA-DLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLD 436
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835])

HSP 1 Score: 66.2402 bits (160), Expect = 3.149e-11
Identity = 68/298 (22.82%), Postives = 122/298 (40.94%), Query Frame = 1 
Query:  229 CPGKSEECKQQFL----TNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLN 1095
            CP +S  C+         +L++ Y+   +       C +K    K       +H+R CSK  V C ++ +GC E+ + T+ + DH    +  H +++L    + + S   L        +    L+  +   EN +  L REVE +         Q+ L  + I     +    K++Q   S+        KD+ +  +   K  E    +  G  +W I    + R+     +  ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L+
Sbjct:  163 CPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTCDGCGKK----KIPRETFQDHVRACSKCRVLCRFHTVGCSEM-VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKI-----EALSNKVQQLERSIG------LKDLAMA-DLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLD 443
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548])

HSP 1 Score: 64.6994 bits (156), Expect = 1.212e-10
Identity = 71/323 (21.98%), Postives = 142/323 (43.96%), Query Frame = 1 
Query:  250 CKQQFL-TNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNK-INEKVDQNALTLNAILLEMSKDFDQK---------------LKQAIYSVNESNEKYRKDILLRFNDPGKYD-------------EEHFDSV-----AGSILWSIE--KINKCRKKGG---SVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            CK+  + TNLQ D++ N+      V CP + C+     + ++ HL  C +    CP+   GC  V      +++H ++ +  H  ++L  N Q++Q +  L    E  ++ + +  ++++   N +   +     L  K +    D++A  L A + ++ +  +Q+               +KQ I  +  S+++    ++L   +  K+D             EE F  +     +G ++W +   ++ K     G   SV S+ FY     Y++    Y NG G+  G+ LS+Y  +      S + WPF+  VT+ +L++
Sbjct:  171 CKRDIVVTNLQ-DHEENS-CPAYPVSCPNR-CVQTIPRARVNEHLTVCPEAEQDCPFKHYGCT-VKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRVNALLSSLE-RKKKMAAADSAIQHATNPMSRFQDIFSFLYRKALTSHTDKSAW-LEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQR----LVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ 483

HSP 2 Score: 55.0694 bits (131), Expect = 1.089e-7
Identity = 47/158 (29.75%), Postives = 70/158 (44.30%), Query Frame = 1 
Query:   13 CKFLLDLMSHSEKLDSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQ-NEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKT-CLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQS 480
            C F+     +S  LD  FE     +++  E + E  KC  C  +L N +Q+ CG  FCQ+CI    + N   +CP   E  K Q +     D      V  L V C     C  +  L    +HL+ CS ++V CP  +  C E  +  D V +H+ +
Sbjct:   12 CAFIRQNSGNSISLD--FE--PDTEYQFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFK---DNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCP--NESCREAMLRKD-VKEHLSA 159
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548])

HSP 1 Score: 64.6994 bits (156), Expect = 1.212e-10
Identity = 71/323 (21.98%), Postives = 142/323 (43.96%), Query Frame = 1 
Query:  250 CKQQFL-TNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNK-INEKVDQNALTLNAILLEMSKDFDQK---------------LKQAIYSVNESNEKYRKDILLRFNDPGKYD-------------EEHFDSV-----AGSILWSIE--KINKCRKKGG---SVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            CK+  + TNLQ D++ N+      V CP + C+     + ++ HL  C +    CP+   GC  V      +++H ++ +  H  ++L  N Q++Q +  L    E  ++ + +  ++++   N +   +     L  K +    D++A  L A + ++ +  +Q+               +KQ I  +  S+++    ++L   +  K+D             EE F  +     +G ++W +   ++ K     G   SV S+ FY     Y++    Y NG G+  G+ LS+Y  +      S + WPF+  VT+ +L++
Sbjct:  171 CKRDIVVTNLQ-DHEENS-CPAYPVSCPNR-CVQTIPRARVNEHLTVCPEAEQDCPFKHYGCT-VKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRVNALLSSLE-RKKKMAAADSAIQHATNPMSRFQDIFSFLYRKALTSHTDKSAW-LEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQR----LVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ 483

HSP 2 Score: 55.0694 bits (131), Expect = 1.089e-7
Identity = 47/158 (29.75%), Postives = 70/158 (44.30%), Query Frame = 1 
Query:   13 CKFLLDLMSHSEKLDSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQ-NEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKT-CLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQS 480
            C F+     +S  LD  FE     +++  E + E  KC  C  +L N +Q+ CG  FCQ+CI    + N   +CP   E  K Q +     D      V  L V C     C  +  L    +HL+ CS ++V CP  +  C E  +  D V +H+ +
Sbjct:   12 CAFIRQNSGNSISLD--FE--PDTEYQFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFK---DNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCP--NESCREAMLRKD-VKEHLSA 159
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041])

HSP 1 Score: 63.5438 bits (153), Expect = 2.681e-10
Identity = 77/316 (24.37%), Postives = 132/316 (41.77%), Query Frame = 1 
Query:  313 LIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGC------------------------DEVAIATDKVIDHIQSEIYSHNSMILGINNQM-------KQSIEMLAHHEE--IH-EENITSLKNSLKEKENQI----------ESLKREVEILTNKINE--KVDQNA--LTLNAILLEMS-KDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            ++V CP K  +     S +  HL  C      C +   GC                         E + + +K +  +Q+E    N  I  ++NQ+       ++  EML ++E   +H +  I S    LKE + +I          +S+K  VE L N++ E   VD++A     N  LLE      DQ L  +++ +  ++   R  +L    +   Y+        G ++W I    + ++     K  S+ S+ FY GY  YKM   +Y NG G   G+ LS++  I      + + WPFK  VT+ ++++
Sbjct:  199 VVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQML--SVHDIRLADMDLRFQVL----ETASYN--------GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ 500
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. UniProt/SwissProt
Match: sp|P70191|TRAF5_MOUSE (TNF receptor-associated factor 5 OS=Mus musculus OX=10090 GN=Traf5 PE=1 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 1.424e-11
Identity = 75/322 (23.29%), Postives = 141/322 (43.79%), Query Frame = 1 
Query:  265 LTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLK----REVEILTN--KINEKVDQNALTLNAILLEMSKDFDQK---------------LKQAIYSVNESNEKYRKDILLRFNDPGKYD-------------EEHFDSV-----AGSILWSIE--KINKCRKKGG---SVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            +TNLQ D++ N+      V CP + C+     + ++ HL  C +    CP+   GC  V      +++H ++ +  H  ++L  N Q++Q I  L    E  E  I  L  ++K+ E +++       R    L+N   +    D++A  L A + ++ +  +Q+               +KQ I  +  S+++    ++L   +  K+D             EE F  +     +G ++W +   ++ K     G   SV S+ FY     Y++    Y NG G+  G+ LS+Y  +      S + WPF+  VT+ +L++
Sbjct:  177 VTNLQ-DHEENS-CPAYPVSCPNR-CVQTIPRARVNEHLTVCPEAEQDCPFKHYGCT-VKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRISDLYQSLEQKESKIQQLAETVKKFEKELKQFTQMFGRNGTFLSNVQALTSHTDKSAW-LEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQR----LVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ 489

HSP 2 Score: 55.4546 bits (132), Expect = 7.275e-7
Identity = 47/158 (29.75%), Postives = 70/158 (44.30%), Query Frame = 1 
Query:   13 CKFLLDLMSHSEKLDSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQ-NEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKT-CLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQS 480
            C F+     +S  LD  FE     +++  E + E  KC  C  +L N +Q+ CG  FCQ+CI    + N   +CP   E  K Q +     D      V  L V C     C  +  L    +HL+ CS ++V CP  +  C E  +  D V +H+ +
Sbjct:   12 CAFIRQNSGNSISLD--FE--PDTEYQFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFK---DNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCP--NESCREAMLRKD-VKEHLSA 159
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 1.955e-10
Identity = 68/298 (22.82%), Postives = 122/298 (40.94%), Query Frame = 1 
Query:  229 CPGKSEECKQQFL----TNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLN 1095
            CP +S  C+         +L++ Y+   +       C +K    K       +H+R CSK  V C ++ +GC E+ + T+ + DH    +  H +++L    + + S   L        +    L+  +   EN +  L REVE +         Q+ L  + I     +    K++Q   S+        KD+ +  +   K  E    +  G  +W I    + R+     +  ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L+
Sbjct:  156 CPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTCDGCGKK----KIPRETFQDHVRACSKCRVLCRFHTVGCSEM-VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKI-----EALSNKVQQLERSIG------LKDLAMA-DLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLD 436
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. UniProt/SwissProt
Match: sp|Q12933|TRAF2_HUMAN (TNF receptor-associated factor 2 OS=Homo sapiens OX=9606 GN=TRAF2 PE=1 SV=2)

HSP 1 Score: 64.3142 bits (155), Expect = 9.184e-10
Identity = 69/296 (23.31%), Postives = 122/296 (41.22%), Query Frame = 1 
Query:  229 CPGKSEECKQQFLTNLQIDYKANNRV-QKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKG-----GSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            CP +S  C+         D KA++ V  K  + C +     K       +H++ C K  V C ++ +GC E  +  +K  +H    +  H +M+L    + K  +   +H      +   SL+      EN +  L REVE +         Q+ L  + I    SK   Q+L+++I   + +     + +L          E    +  G  +W I    + R++       ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L++
Sbjct:  156 CPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTC-DGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLET-VEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKV--QQLERSIGLKDLAMADLEQKVL----------EMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ 437
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. UniProt/SwissProt
Match: sp|Q13114|TRAF3_HUMAN (TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=2)

HSP 1 Score: 64.3142 bits (155), Expect = 1.098e-9
Identity = 77/316 (24.37%), Postives = 133/316 (42.09%), Query Frame = 1 
Query:  313 LIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGC------------------------DEVAIATDKVIDHIQSEIYSHNSMILGINNQM-------KQSIEMLAHHEE--IH-EENITSLKNSLKEKENQI----------ESLKREVEILTNKINE--KVDQNA--LTLNAILLEMS-KDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            ++V CP K  +     S +  HL  C      C +   GC                         E + + +K +  +Q+E    N  I  ++NQ+       ++  EML ++E   +H +  I S    LKE + +I          +S+K  VE L N++ E   VD++A  +  N  LLE      DQ L  +++ +  ++   R  +L    +   Y+        G ++W I    + ++     K  S+ S+ FY GY  YKM   +Y NG G   G+ LS++  I      + + WPFK  VT+ ++++
Sbjct:  200 VVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQML--SVHDIRLADMDLRFQVL----ETASYN--------GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ 501
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2)

HSP 1 Score: 63.5438 bits (153), Expect = 1.875e-9
Identity = 77/316 (24.37%), Postives = 132/316 (41.77%), Query Frame = 1 
Query:  313 LIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGC------------------------DEVAIATDKVIDHIQSEIYSHNSMILGINNQM-------KQSIEMLAHHEE--IH-EENITSLKNSLKEKENQI----------ESLKREVEILTNKINE--KVDQNA--LTLNAILLEMS-KDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            ++V CP K  +     S +  HL  C      C +   GC                         E + + +K +  +Q+E    N  I  ++NQ+       ++  EML ++E   +H +  I S    LKE + +I          +S+K  VE L N++ E   VD++A     N  LLE      DQ L  +++ +  ++   R  +L    +   Y+        G ++W I    + ++     K  S+ S+ FY GY  YKM   +Y NG G   G+ LS++  I      + + WPFK  VT+ ++++
Sbjct:  199 VVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQML--SVHDIRLADMDLRFQVL----ETASYN--------GVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ 500
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. TrEMBL
Match: I1ZID8 (TNF receptor associated factor-2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 2.943e-37
Identity = 71/203 (34.98%), Postives = 120/203 (59.11%), Query Frame = 1 
Query:   55 DSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLT---NLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEIL 654
            + I  L++  +FE    + ++LKC LC+ +L+NA QS CGC FC KCI E++      CPG + ECK++ LT   N+  DY+ N ++ K+ VKCPE+TC   C+L +++ HLR C+ KS  CP++ LGC++  +    + +H+Q+  + H+ +I+ I + M+     L   E    E+I  +KN  + +   +  +  E+EI+
Sbjct:    4 EKINRLLITYNFEVEGGVPDNLKCDLCKNLLVNACQSRCGCRFCSKCIMEYVSRGNLYCPGGTSECKEENLTICSNIHTDYRVNRKIAKMRVKCPEETCKVYCELVDIEEHLRLCTMKSQNCPFFVLGCNQPKMVIQDLTNHLQNGTFQHSKLIIDIISNMRNDFFGLTTKEVELREDINLIKNHFQSQNEIMMLINSEIEII 206
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. TrEMBL
Match: T1E101 (TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 7.181e-30
Identity = 108/415 (26.02%), Postives = 195/415 (46.99%), Query Frame = 1 
Query:   49 KLDSIFELIMK-NDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDY----KANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLK-------EKENQIESLKREVE-------ILTNKINEKVDQNALTLNAILLEMSK------DFDQK----------------------LKQAIY----SVNESNEKYRKDI--LLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKY 1134
            KLD++ EL+ K N     E+++ DL C+LC K++ +A +S CGC +C  CI  ++      CPG   ECK+ +L NL+ D     + + R+ +++VKCP   C Y  +L  +  HL  C+ +SV+CP   +GC+E  +  D++  H+  ++  H  +I+   N++K  I    H+ E  +E+I+ LK  L+       EK  Q+E L  E+        +L+  I E  ++    L +   E+ K       F Q+                      LK+ I+    +++ +NE+  + +  L+R N       +   +V    +W IE+ +K R+    V S+ F     K+ + L +Y        G  L ++  I    K   ++WP +  VT+ ++ + D+  + K + +
Sbjct:    5 KLDNVQELLSKYNVKRVDESVNNDLLCILCNKLMRDACESACGCHYCYTCIRIYLSQNHNYCPGDKTECKEDYL-NLEGDVFRNIRLSTRISRIVVKCPNIRCNYTSELLRLKEHLDKCTPESVECPCVTIGCEEEPLLKDEMAKHLTDQVLRHTQLIMSFCNELKSEIN---HNNETTKEDISHLKEVLRVQKALNDEKTAQMEFLIEELRNKDNMILVLSQDIQEVKNEMITLLTSKESELKKLKSDIQIFRQEIEFMKNDLEVVGSTDIKNQVKDLKKEIFGIKMNIDSNNEERERKMNNLIRLN-------KLCPNVDMDFMWRIEEYSKKRRTVTDVYSDSFQSHNYKFCLNLYIY--------GDNLGLWCVIMKGEKDDFLEWPMRRTVTLSIIEQ-DSLKTHKTTVF 399
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. TrEMBL
Match: A0A0P7UP01 (TNF receptor-associated factor OS=Scleropages formosus OX=113540 GN=Z043_109893 PE=3 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 3.835e-20
Identity = 105/406 (25.86%), Postives = 176/406 (43.35%), Query Frame = 1 
Query:   73 IMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNE--PKLCPGK----------SEECKQQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSE----------IYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKIN----------EKVDQNALTLNAILLEMSKDFD-----------QKLKQAIYSVNESNEK--------YRKDILLRFN-DPGKYDEEHF-----DSVAGSILWSIEKINKCRKKGGSVE-------SEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            +M  +F+  E + +   C  C ++++N +Q+ CG  FC +CI+ F+ ++  PK CP             + C ++ + NL+I Y  N              C  K  L  + +HL+ C  +SV+CP  + GC E     D V DH+ S+             H ++I  + + ++ S+ +L HHE    +  TSL  SL   ENQ++ L +E+    N I           ++VD   L L  +    S+D               LKQ + ++    E+         R   LL  + D  + +EE F      S  G ++W I    K ++   + E       S  FY   + YK++   Y NG G+  G+ LS+YI +      S + WPF+  V++ VL++
Sbjct:   33 LMTREFKFVEKLEDQYVCPTCGQVVLNPHQTGCGHIFCYQCIQGFLDSDITPK-CPIDDSFIKANEVFQDNCCKREIANLEI-YCTN-----------APNCSSKVTLCRLQDHLKICQYESVQCP--NSGCSETLFRKD-VGDHLDSQCRYRLEPCPYCRKHYAVIHLMIDDLQHSL-VLKHHE---FQERTSLAGSL---ENQVKPLVQEMTRCDNMIGTVQRSLEEQKDRVDSVQLQLQQLTRAFSQDLGCTELAQLRGSLDSLKQQVSAIEGLKERLVMLEDNYMRHSRLLNIHVDQFQRNEERFRELESTSYNGKLIWKIRDYQKKKEAAAAGEGRSPFMLSAPFYTSRSGYKLRARAYLNGDGSGRGTHLSLYIVLMRGDFDSLLPWPFQQPVSLTVLDQ 415
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. TrEMBL
Match: I1ZID7 (TNF receptor associated factor-3 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 1.521e-18
Identity = 52/178 (29.21%), Postives = 98/178 (55.06%), Query Frame = 1 
Query:  778 EKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVE 1311
            +++++ I L+  +   Y ++  D  +G   W++  I+  RK+  S+ SEYFY   +K+K+ L   AN + ++   G +++++I+   + SK++WPF+  VTIK++N+     SV  S   +   F   +++             C+Y W + F F Y+ELS +G+L N+  T+EC V+
Sbjct:   55 QEFQERIELKVQNIESYLKQKIDETSGIFSWNVNGISAKRKENQSMFSEYFYTKVSKHKVSLQFTANVSNDINEIGFNVFLFIFSGIQESKLNWPFQANVTIKIVNR-----SVPDSSKIVTKCFR--IEEP-----------PCNYNWSDPFYFCYDELSGAGLLLNDSFTIECFVD 214
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. TrEMBL
Match: A0A452IC94 (TNF receptor-associated factor OS=Gopherus agassizii OX=38772 GN=TRAF5 PE=3 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 4.238e-17
Identity = 101/405 (24.94%), Postives = 170/405 (41.98%), Query Frame = 1 
Query:   85 DFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQ-NEPKLCPGKSEE-----------CKQQFLTNLQIDYKANNRVQKLIV----------KCPE--KTCLYKCKL----SNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKR------EVEILTNKINEKVDQNALTLNAI--LLEMSKD----FD-QKLKQAIYSVNES---NEKYRKDILLRFNDPGKYD-------------EEHFDSVAGS-----ILWSIE--KINKCRKKGG---SVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            D+   E + E  KC  C  +L N +Q+ CG  FCQ CI    + N    CP   E            CK++ L NLQ+  K        I+          +CP+    CL+KC        MD H   C +  V CPY   GC  V I   K+++H  + +  H   IL  N+++++ I  L    E  E  I  L +++K+ E       +       + + T  +   +D++A     +  L+++S      FD + L + I ++ +     E Y + +++      ++D             EE F  + G+     ++W I   K+ K     G   S+ S+ FY     Y++    Y NG G+  G+ +S+Y  +      S + WPFK  VT+ +L++
Sbjct:   31 DYRFVETLEERYKCAYCHLVLHNPHQTGCGHRFCQHCIISLRELNAVPTCPVDKETIKVQEVFKDNCCKREVL-NLQVFCKNFPECNSKIILGRYQNHEKNECPDFPVPCLHKCSQIILKKEMDKHFSVCPEAEVDCPYKQYGCP-VQIKRGKLVEHENAALREHMLQILDKNSKLEEQISDLYKSLEFKEIKIQQLADTVKKCEKDFRQFAQLLGKNSNLMVNTQTLASHIDKSAWLETQVRQLIQVSNQQQSKFDLRPLLETIENIKQKIAFMETYDQRLVVLEGQSTEHDVHISIHKAQLNKNEERFKLLEGTCYNGKLIWKIMDYKMKKKEAMEGRIVSIFSQPFYTSRCGYRLCARAYLNGDGSGKGTHVSLYFVVMRGEFDSLLPWPFKQKVTLMLLDQ 433
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Cavefish
Match: traf5 (TNF receptor-associated factor 5 [Source:NCBI gene;Acc:103031120])

HSP 1 Score: 83.9593 bits (206), Expect = 5.035e-17
Identity = 63/288 (21.88%), Postives = 135/288 (46.88%), Query Frame = 1 
Query:  319 VKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEML-----AHHEEIHEEN----------------ITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNAL-TLNAIL--LEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFN----DPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            V+CP K C++  K   + +H   C ++   C Y   GC  V     +V  H Q+E   H  ++L  N+++ + ++ L     A   E+ E N                +++++ S++E+   + S+KRE++ L + +   + +  L +L A L  L       Q L++ + ++ ++ + + + + +          ++ +    S  G ++W +   ++ ++ G ++ S  FY  ++ YK+   +Y  G G   G+ LS+Y+ +      S + WPF+  VT+ VL++
Sbjct:  195 VQCPNK-CIHLVKRHKLKDHADECPEQETDCIYKKYGCT-VRNKRGQVKVHEQTEFNHHVLLLLESNSKLIKQVDQLQQDFAAQQGELKERNLLVSNLKREVSKCDTTVSAMQRSVEEQRELVSSVKRELKDLRDVLEADLTKEELVSLRASLDSLREQVAMTQSLREHLGALGQTCQSHTRLLDIHVQQLQCSEQRFQQLESTSYDGKLIWKVHDYHRKKEAGTALNSPPFYTSHSGYKLSARVYLGGEGTARGTHLSLYVMLMRGDFDSLLPWPFRQNVTLAVLDQ 480
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375])

HSP 1 Score: 62.003 bits (149), Expect = 5.717e-10
Identity = 67/311 (21.54%), Postives = 130/311 (41.80%), Query Frame = 1 
Query:  373 NHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSM----ILGINNQMK----QSIEMLAHH-EEIHEE---------------------------------NITSLKNSLKEK-ENQIESLKREVEILTNK-----------------INEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLR----FNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            +H++ C+K    C ++ +GCD +++  +K+ DH ++  Y H ++    I+GI   ++    QS+E+ +H  +E+H+                                  + T L  ++    E Q+ S K +V  L+ +                 +N +++++A T+ A   +   D D+     I  +N    +  + + LR        GK  E    +  G  +W I   +K R+     +  ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L++
Sbjct:  204 DHIKLCTKFRTPCRFHVVGCD-MSVEKEKIHDHERACSYEHLNLLLHFIMGIKVNLESLQPQSLELASHKIQELHQSLRELELKMGQLSAGAPVQGACAPPPPPPPTLATSFTPLPTTVGAALELQLHSEKTKVAELSRRCQELELKVGTFENIVCVLNREMERSATTMEAYNRQHRLDQDK-----IEILNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ 508
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Cavefish
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:103024022])

HSP 1 Score: 60.4622 bits (145), Expect = 1.671e-9
Identity = 73/326 (22.39%), Postives = 126/326 (38.65%), Query Frame = 1 
Query:  184 CQKCIEEF----IQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKT--CLYKCK---LSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLA---HHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQ 1125
            C+ C  EF     +N   +CP +S  C+ +    +     A    Q  + +CP++T  C Y  K      + NH   C +  V+CP     C    IA + +  H++    S   +    +   K     LA   H EE  + ++T + + +  +  +I  L+RE+E L+           ++ + +L+    D+ +KL++A    N             F+ P                                    FY     YK+++  + NG G+  GS LSIYI + P    + ++WPF   VT  +L++ D   S  Q
Sbjct:  141 CEFCGSEFTGEAFENHQGICPQESVYCENKCGARMMRRLLA----QHTMAECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQ---CGTPNIAREDLATHVKESCGSALVLCPFKDAGCKHRCPKLAIGRHLEETTKSHLTMMCSLVGRQRQEIIELRREMEELS-----------VSHDGVLIWKLNDYSRKLQEAKLHNNHEF----------FSPP------------------------------------FYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQSDPSLSKPQ 402
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261])

HSP 1 Score: 58.9214 bits (141), Expect = 5.719e-9
Identity = 67/308 (21.75%), Postives = 126/308 (40.91%), Query Frame = 1 
Query:  229 CPGKSEECKQQFLTNLQIDYKANNRV-QKLIVKCPEKTC-LYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEE--------IHEENITSLKNSLKEKENQIESLKREVEILTNKI---NEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            C  ++  CK   +T    D KA++ + QK  ++C  K C   K        H + C+K    C + ++GC  V +   K  +H QS I  H  ++L + + ++   +     +E          E+      ++          +++++  L N +   N +V++  L L A+  +   D  +K++     V +         L          E  F +  G  +W I   ++ R+     +  ++ S  FY     YKM L +Y NG G   GS LS++  +      + + WPF   VT+ +L++
Sbjct:  164 CEARTLNCKYCKVTFSFKDIKAHDEICQKFPMQC--KDCGKKKIPREKFAEHSKSCAKSKSACQFSEIGCRAV-VDNGKQHEHEQSSIIEHLRLMLAVLSTVRVRSDGPGEWQEDSGLGLYRGPEDAAPPGAHAAAHNAAGGPGVQQKMTALENIVCVLNREVERTVLRLEALTRQQQLD-QEKIENLSNKVRQLERTLTMRDLQLAESEQALRELQFCTYDGVFVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQ 467
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375])

HSP 1 Score: 57.3806 bits (137), Expect = 1.564e-8
Identity = 84/383 (21.93%), Postives = 147/383 (38.38%), Query Frame = 1 
Query:  124 CMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPK--------LCPGKSEECKQQFLTNLQIDYKANNRVQ--KLIVKCP---------------EKTCLYK---CKLSNMDNHLRFCSKKSVKCPYYDL---GCDEVAIATDKVIDHIQ------------------SEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLR----FNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            C +C+KIL   +Q+ CG  F       F  N  K        +C   +E C     T    +Y+A +  Q   +I+ CP               E+ C  +   CK      H +        CP Y +   GC +  I  +K +DHI+                  S      ++IL   + +  S  +      + +  +  L    +E E ++ + +  V +L    N +++++A T+ A   +   D D+     I  +N    +  + + LR        GK  E    +  G  +W I   +K R+     +  ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L++
Sbjct:   34 CNICQKILRRPFQAQCGHRFSPA--SAFPDNAAKREVEALEAVC--INEGCS---WTGTIKEYEATHEGQCDFMIIPCPSCKELLRANELERHNERECPERTLNCKYCKEPFHFKNIKAHDEICPKYPMICEGCAKKKIPREKYVDHIKLCTKFRTPCRFHVVGCDMSVSKPQWNLILTPRDLLYTSFTV-----PLSQTKVAELSRRCQELELKVGTFENIVCVL----NREMERSATTMEAYNRQHRLDQDK-----IEILNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ 395
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Nematostella
Match: EDO48773 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI91])

HSP 1 Score: 78.1814 bits (191), Expect = 1.138e-15
Identity = 88/418 (21.05%), Postives = 165/418 (39.47%), Query Frame = 1 
Query:   46 EKLDSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKC---PEKTCLYKCKLSNMDNHLRFCS---------------KKSV------KCPYYDLGCD--EVAIATDKVIDHIQS-------------------EIYSH------NSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDI---LLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKG-----GSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVK 1122
            E  D  F+  +++ +E          C +C   L +  Q+PCG  FC  CI   I++    CP  +    ++    L  D  A   +   IV C    E+ C +K  L  ++ HL+ C                +K V       CP   + CD  ++ +   K+ +H++                    E+  H      N  +   + +MK S E  +H  + H  +   L+   +E   Q  +++REV++L ++ +E                 + F   L++ +  V  S+++   ++   L+R     +  E       G+ +W ++   +CR+        ++ S  FY     YKM L M  NG     G  +S++I++        ++WPF G +T+ +L++ D   S +
Sbjct:   42 EGYDEFFDPPLESKYE----------CPICLLGLRDPVQTPCGHRFCFNCIRRSIRDAGPKCPVDNTPLSER---ELYRDNFAKREMMSFIVWCRLKKERGCTWKGALKELEEHLKGCPCMDTNCPNECGAVMQRKEVDKHCAEACPNRSVPCDHCKMKVTISKIEEHLKGCPCMDTNCPNECGAVMQRKEVDKHCAEACPNRSVPCDHCKMKSSKEQASHGPQEHTPHEAELR---REALFQSANMQREVDMLGSRGDE----------------YRQFLAYLERKVEDVKTSSDRRIAELTHKLMRLET--REIELEGRVCNGTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGLGEHVSLFIHMMQGDWDGILEWPFIGRITLSILDQSDQIDSRR 425
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36])

HSP 1 Score: 68.1662 bits (165), Expect = 2.700e-12
Identity = 96/458 (20.96%), Postives = 166/458 (36.24%), Query Frame = 1 
Query:   97 TENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEE-----------CKQQFL------TNLQI------------DYKAN---NRVQKLIVKCPEKT---------------------CLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDH-----------------------IQSEIYSH---------NSMILGINNQMKQSIEMLA-----------HHEEIHE---------ENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNAL-----TLNAILLEMSKDFDQKLKQAIYSVNESNEKYR---------KDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKG-----GSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
             E +    +C +C   L +  Q+PCG  FC+ C+E  ++  P  CP   EE           C+++ L       N Q+            +++AN     VQ     C EK                      CL +   ++M++HL+ C K  V CP+    C    I  D+++ H                        +  + +H         N ++    N+ K   EM A             E+++E         +N+ + +  L   E  +   +RE+  L  +I  +  + A+      L  I  E S+               + E+ +          DI L  +D  K       S  G+ +W I++  +  ++G      S+ S  FY+G   YK    +Y NG G   GS LS++  +      + + WPF+  VT K+L++
Sbjct:   12 VEPLDPKYRCPVCGNALKHPVQTPCGHRFCEGCLEPILRG-PSKCPVDGEELKIDGVFKDVCCRREILCLACYCPNRQLGCEWMKDLQYLEEHRANCEYKGVQCHNPGCQEKVAKRDLEAHLERCEFKPSDCQYCLQRIPAASMEDHLQTCEKHPVVCPH----CGAEGICRDELLHHQTNICEQAELPCSFAKHGCHFKGTREALETHFRDQASVHVNLLLTATQNEEKARSEMAAKLSQMEKERAKQQEQMYEQREALAVANQNLRTYQGKLNVIERSVAEQRRELAELKERIQLQEVEAAIREQDRRLGMIENEASRGAAPSSGPGSMGGTMALERRQDRNEHQLALHDIQLAEHD-LKLQMLEATSYDGTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQ 463
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Nematostella
Match: EDO48394 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJK8])

HSP 1 Score: 65.855 bits (159), Expect = 1.154e-11
Identity = 87/425 (20.47%), Postives = 171/425 (40.24%), Query Frame = 1 
Query:  109 SEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQN-EPKLCPGKSEECK-QQFLTNLQID--------------------------------YKA--------NNRVQKLIVKCPEKTCLYK---CKLSNMD---------NHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEI-------------HEENITSLKN----SLKEKENQIESLKREVEILTNKINEKVDQ-----NALTLNAILLEMSKDFDQKLKQA----------IYSVNESNEKYRKDILLRFNDP---GKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFAS 1116
            +++L C +C  ++     + CG S+C+ CIE++    E   CP  +E+ K  Q   + + D                                +KA        N +V +++++    TC ++   CK  N+           H   C    + C + ++GC      + +  +H +S + +H  +        K+ I  L  H+E+             H + + +++     ++++ + QIE+L +E  I +N I+E  +Q       L + +  +  ++D   KL  A          ++ +    +KY+K +    N     G  D +   S+AG I+ S+                 FY     YKM+L  Y NG G+  G+ LS+ I I      + ++WPF+  +T+ ++N+ + + S
Sbjct:   25 NDELICAICHMVVNEPVLTSCGHSYCKYCIEKWCNGKEVVTCPVDNEQLKPSQIFPDKKTDRIVLSLEVKCTNNPCRWKGELRQKQKHLKICSHKAVKCILEGCNVKVPRILMEKHTNTCGWRLLHCKPCNLSYPKKDEETVQHKDDCPLAFLPCRFSEIGCTFKGRESARD-EHCESAVQTHLHIACETIRDNKEQISDL--HKELDKVRQELQTKSCDHMKEVNAIREKHDEAIRDNKGQIEALSKEHGIASNTIHENKEQLDTLKKELGIASETIRKNRDQIAKLSTACKTQYTDGTFVWRICNYKDKYKKAVAFATNQEVKGGNSDSDDDISMAGDIMVSLP----------------FYTSRYGYKMRLKAYPNGYGDGKGTHLSLSIRIMKGEYDAILEWPFRRKITLSLINQSEQWRS 430
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Nematostella
Match: EDO43806 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXN6])

HSP 1 Score: 55.0694 bits (131), Expect = 2.728e-9
Identity = 35/110 (31.82%), Postives = 51/110 (46.36%), Query Frame = 1 
Query:  100 ENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQ---NEPKLCPGKSEECKQQFLTNLQIDYKA-NNRVQKLIVKCP--EKTCLYKCKLSNMDNHLRFCSKKSVKC 411
            E +  +L C +C ++L  A  +PCG SFC  C+E ++     E + CP     C+        I   A    V  LIV CP  +  C    KL  ++ HL+ CS   V+C
Sbjct:   10 EKVDPNLLCGICAEVLERAVLTPCGHSFCGVCLETWMNAKLGENEKCPASCPSCRADLYQGDTIPVLALRGIVDGLIVHCPNADNGCKLVLKLEGVEGHLKSCSHAPVQC 119
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Nematostella
Match: EDO37750 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SER6])

HSP 1 Score: 56.9954 bits (136), Expect = 7.371e-9
Identity = 38/157 (24.20%), Postives = 75/157 (47.77%), Query Frame = 1 
Query:  862 ILWSIEKINKC-----RKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVEIK 1317
            +LW I+   +      RK G  + S  FY     YK K++++  G G+  G+ LS+YI + P    S + WPF+G +T+ +L++    ++ K++K  I  +F     D     F   S +S    +       +  L + G + ++++ ++  ++ K
Sbjct:  315 LLWRIDDFWEAFDEGKRKPGTELHSPVFYTSNYGYKFKVVLFPYGNGSGEGTHLSLYIRLLPGEYDSLLPWPFEGQITLTLLDQ----STDKRAKRHISQSFSP---DPNWKSFQRPSKNSTSLGFGYPQFVSHRGLESIGYVRDDVLFLKVTIDCK 464
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601])

HSP 1 Score: 66.6254 bits (161), Expect = 1.646e-11
Identity = 79/348 (22.70%), Postives = 140/348 (40.23%), Query Frame = 1 
Query:  124 CMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKT--CLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKN-----SLKEKENQIESLKREVEILT------NKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDIL----LRFNDPG-KYDEEHFDSVAGSILWSIE-----KINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            C  C  +L    Q+ CG  FC  CI + +     +CP   E     F   +  D   +  +  L V C  +   C  +  L  + +H+  C    V CP   LG  +  +   ++ +H+  +     S      N+M  + E+  H E +      S  N     SL   E  + S   ++  L        ++ ++++    TL+ +   +S      L+Q   +  E+      D+L    +R  D   ++      S  G+++W I      K +    K  S+ S+ FY GY  YKM   +Y NG G   G+ LS++  +      + + WPFK  VT+ ++++
Sbjct:   48 CEACRLVLCQPRQTECGHRFCYSCINDILSCPNPVCPADMEP---LFKDKIFRDVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCP---LGKCKERMMRKEIPEHLAWKCKYRESTCEFCKNKMPLT-ELQKHKETVCPAFPVSCPNHCTSSSLPRSEKLMSSHTEKLLELELELRSLRQLRDEMESLRGTLDTVRTRLSA-----LEQGGRASLETQLNRHDDMLSVHEIRLADMDLRFQVLETASYNGTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQ 383
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Medaka
Match: ENSORLT00000001369.2 (TNF receptor-associated factor 5 [Source:NCBI gene;Acc:101170323])

HSP 1 Score: 66.6254 bits (161), Expect = 2.305e-11
Identity = 66/333 (19.82%), Postives = 139/333 (41.74%), Query Frame = 1 
Query:  229 CPGKSEECK---QQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSI-----EMLAHHEEIH-----------------------EENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNA---LTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPG----KYDEEHFDSVAGSILWSIEKINKCRKKGGS-----VESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            CP + E C    Q F  ++  D+   +   ++ V CP+  C      + +  H   C +    C +   GC  V     KV  H ++ +  H  ++L  +  ++Q +     E L   +E+                        E  + + + +L  +E+ + S++ +++ ++  +   +D+      +L+ ++ E+     + L++ I ++ E+ +++   + L             E    S  G ++W I+   K R+   +     + S  F+ G   YKM +  Y NG G   G+ LS+Y+ + P    + + WPFK  V++ VL++
Sbjct:  186 CPHRRESCPHCLQPFQLSVIQDH-VQSSCPEVKVGCPDG-CSTLVPRNRLTEHGESCPEVHTDCSFKMFGCS-VKGKRRKVKLHEEAAVCHHVLLVLKSSAHLEQQVVFVQKEALLRQQEVQTDTLLLSDLQEQLGSVLQQSRSQEHIVATAQRTLSRQEDALSSVQLDLQQVSCGMGSGLDELRRFKTSLDGVMQELLAA--ETLREHIATLEENRKRHSGLLELHVAQLALNKQHLQELELTSYDGRLIWKIKDFQKRREAEATGQHPCLSSVPFHTGRCGYKMAMKAYLNGDGEGRGTHLSLYVVLMPGDFDALLPWPFKQTVSLSVLDQ 513
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764])

HSP 1 Score: 64.3142 bits (155), Expect = 1.179e-10
Identity = 69/293 (23.55%), Postives = 127/293 (43.34%), Query Frame = 1 
Query:  283 DYKANNRV-QKLIVKCPEKTC-LYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIES-----LKREVEILTNKI---NEKVDQNALTLNAILLEMSKD------FDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            D KA++ + QK  ++C  K C   K      ++H + C+K    CP+ ++GC  V +   K+ +H  S    H  ++L +   M ++    +   E  E++   L  +  +      S     L ++V  L N +   N +V++++LTL A   +   D         K++Q   S+        KD+ L   +     E  + +  G  +W I   +  R+     +  ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L++
Sbjct:  170 DIKAHDEICQKFPLQC--KDCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSV-VENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNREVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTV------KDLQLSEAE-QMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQ 452
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764])

HSP 1 Score: 63.929 bits (154), Expect = 1.313e-10
Identity = 69/293 (23.55%), Postives = 127/293 (43.34%), Query Frame = 1 
Query:  283 DYKANNRV-QKLIVKCPEKTC-LYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIES-----LKREVEILTNKI---NEKVDQNALTLNAILLEMSKD------FDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            D KA++ + QK  ++C  K C   K      ++H + C+K    CP+ ++GC  V +   K+ +H  S    H  ++L +   M ++    +   E  E++   L  +  +      S     L ++V  L N +   N +V++++LTL A   +   D         K++Q   S+        KD+ L   +     E  + +  G  +W I   +  R+     +  ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L++
Sbjct:  177 DIKAHDEICQKFPLQC--KDCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSV-VENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNREVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTV------KDLQLSEAE-QMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQ 459
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Medaka
Match: ENSORLT00000020861.2 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101167626])

HSP 1 Score: 63.5438 bits (153), Expect = 2.270e-10
Identity = 64/302 (21.19%), Postives = 121/302 (40.07%), Query Frame = 1 
Query:  373 NHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHE-EIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALT-----LNAIL-----------LEMSKD-----------------FDQKLKQAIYSVNESNEKYRKD-----------------ILLR----FNDPGKYDEEHFDSVAGSILWSIEKINKCRK-----KGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNK 1098
            +H++FCSK    C ++ +GCD  ++  +K+ DH +   Y H +++L     +K S+E L     E+  + +  L  SL++ E ++  L R        +       + T     + A L            E+S+                   +++L+++  ++   N ++R D                 + LR        GK  +    +  G  +W I    K R+     +  ++ S  FY     YKM L +Y NG G   G+ LS++  +      + + WPF   VT+ +L++
Sbjct:  205 DHIKFCSKFKAPCRFHVVGCD-TSVEKEKIHDHERQCSYEHLNLLLHFIMGIKVSLESLQPQRLEVASQKLHELHQSLRDLELRMSQLGRSGTAPLQGVCAATLATSFTPLHSAMGAALELQLQSEKTKVAELSRRCQELELKVSTFENIVCILNRELERSCATMEAYNRQHRLDQDKIEILSNKVRQLERTVSLRDLSIVEMEGKMKDMSAATYDGIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ 505
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Planmine SMEST
Match: SMESG000024592.1 (SMESG000024592.1)

HSP 1 Score: 867.84 bits (2241), Expect = 0.000e+0
Identity = 425/428 (99.30%), Postives = 426/428 (99.53%), Query Frame = 1 
Query:   34 MSHSEKLDSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVEIK 1317
            MSHSEKLDSIFELIMKNDFEA ENISEDLKC LCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLL+YANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVEIK
Sbjct:    1 MSHSEKLDSIFELIMKNDFEAIENISEDLKCTLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLLYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVEIK 428
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Planmine SMEST
Match: SMESG000024592.1 (SMESG000024592.1)

HSP 1 Score: 796.193 bits (2055), Expect = 0.000e+0
Identity = 394/414 (95.17%), Postives = 396/414 (95.65%), Query Frame = 1 
Query:   76 MKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVEIK 1317
            MKNDFEA ENISEDLKC LCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLL+YANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQ                +GSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVEIK
Sbjct:    1 MKNDFEAIENISEDLKCTLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLLYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQ----------------KGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVEIK 398
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Planmine SMEST
Match: SMESG000024548.1 (SMESG000024548.1)

HSP 1 Score: 246.128 bits (627), Expect = 1.055e-76
Identity = 138/443 (31.15%), Postives = 239/443 (53.95%), Query Frame = 1 
Query:   25 LDLMSHSEKLDSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEIL-TNKIN-------------EKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVE 1311
            + L +   +++   +L+  +  E   ++S DL C +CEKIL++A QS CGCSFC+ C+ E++    + CPG ++ECK + L ++Q DYK N  + KLIVKC E  C YKC+L N+++HLR C KKS KCPY+D+GC    I  +++ DH+  E  +H+ +++     +K  +  +    + ++  I +L+ +LK  E  I  +  E++IL TN  N             EK+++N   LN ++  + +  ++K  Q ++   +  +  + +++ R +   KY +E      G  +W +  I   R K G + SE+F+   N Y+M+L + ANG+G V   GL++ +  YP      + WPF   VTI ++NK D       +K C ++  +E               +S  ++W++ FDF+YN+L ++ V  ++   VEC V+
Sbjct:   11 IQLANRITEMNFAHKLLQLHQLEIYSDLSSDLICGMCEKILIDACQSRCGCSFCRNCVNEYLLTGNETCPGNTDECKTESLLSIQTDYKVNKIISKLIVKCTETLCCYKCELINLEDHLRLCPKKSAKCPYFDIGCSVEKIVIEEMSDHLIKENCNHSKLMVDAIGSLKNEVSNIKRTSDTYKMEIETLRETLKRNEEFIYKISDEIQILKTNSFNKLSQFEDSIQSIKEKLERNE--LNLLIDRVQQKLEEKFLQEVHQKIDEMKYDKIEMVKRISVVEKYMDEKLKKALGLFVWDVNDITSKRNKFGYLWSEHFFTKPNFYRMRLHLCANGSGAVKDVGLTLLLCSYPSVNDEFLTWPFSKEVTITLINKNDPLIKSCVTKMCFLNRPKE---------------NSYSFEWNDSFDFVYNDLISNNVFTDDGFIVECQVK 436
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Planmine SMEST
Match: SMESG000024584.1 (SMESG000024584.1)

HSP 1 Score: 224.942 bits (572), Expect = 9.087e-69
Identity = 133/438 (30.37%), Postives = 237/438 (54.11%), Query Frame = 1 
Query:   55 DSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLT---NLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKREVEILTNK----INE----KVDQNALTLNAILLEMSKDFDQKLKQ--------AIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNVE 1311
            + I  L++  +FE    + ++LKC LC+ +L+NA QS CGC FC KCI E++      CPG + ECK++ LT   N+  DY+ N ++ K+ VKCPE+TC   C+L +++ HLR C+ KS  CP++ LGC++  +    + +H+Q+  + H+ +I+ I + M+     L   E    E+I  +KN  + +   +  +  E+EI+  +    INE    K++     ++  L+E  K  + K KQ         +  +    +++++ I L+  +   Y ++  D  +G   W++  I+  RK+  S+ SEYFY   +K+K+ L   AN + ++   G +++++I+   + SK++WPF+  VTIK++N+     SV  S   +   F   +++             C+Y W + F F Y+ELS +G+L N+  T+EC V+
Sbjct:    4 EKINRLLITYNFEVEGGVPDNLKCDLCKNLLVNACQSRCGCRFCSKCIMEYVSRGNLYCPGGTSECKEENLTICSNIHTDYRVNRKIAKMRVKCPEETCKVYCELVDIEEHLRLCTMKSQNCPFFVLGCNQPKMVIQDLTNHLQNGTFQHSKLIIDIISNMRNDFFGLTTKEVELREDINLIKNHFQSQNEIMMLINSEIEIIKKENIECINEFKNLKIEVEDKMVD--LVEKIKLAETKTKQECAEIVTAEVSKLRRDFQEFQERIELKVQNIESYLKQKIDETSGIFSWNVNGISAKRKENQSMFSEYFYTKVSKHKVSLQFTANVSNDINEIGFNVFLFIFSGIQESKLNWPFQANVTIKIVNR-----SVPDSSKIVTKCFR--IEEP-----------PCNYNWSDPFYFCYDELSGAGLLLNDSFTIECFVD 421
[Close]
BLAST of TNF receptor-associated factor-2-like protein B vs. Planmine SMEST
Match: SMESG000024504.1 (SMESG000024504.1)

HSP 1 Score: 205.682 bits (522), Expect = 7.929e-61
Identity = 130/437 (29.75%), Postives = 225/437 (51.49%), Query Frame = 1 
Query:   52 LDSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSFCQKCIEEFIQNEPKLCPGKSEECKQQFLT--NLQIDYKANNRVQKLIVKCPEKTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSEIYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESLKRE--------------VEILTNKINEKVDQNALTLNAILLEMSKDF--DQKLKQAIYSVNESNEKYRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFYLGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTIKVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQFDFLYNELSASGVLDNNIITVECNV 1308
            L  +F+++ K DF+   + S++ KC +C++IL NA Q  CGC +C KC  + + +E K CPG SE CK   L   N+QID++ NN + K++VKCP K C ++ +L +MD HLR CS K  KCP++  GC    +   K+ ++++ EI+SH+ +++ + + +K     L + +  +E ++ +++N L E   QI+ L++E              V  LT K+  KV  N+   ++I L   K F  D+KL + +  +   N +   D      +     E     +  +I W IE++++ +KK    +S +FY   +++K+ L  +ANG     G+  +I+  +    K S + WPF   + I++ N     +S++  K C               L M +S     +   + FDF YNEL   G+L ++ + +EC V
Sbjct:   46 LQRMFKILNKYDFKIERSNSDEYKCEICKRILCNACQGECGCRYCSKCFADLLNSESKFCPGNSELCKDLQLAENNIQIDHRMNNELLKMVVKCPNKLCSFETELKDMDKHLRVCSSKVDKCPFHQFGCGHDKVKCSKMDEYLKDEIFSHSKILIEVISNIKNDTSELWNMKIKYENDLKTIQNELVENREQIQILRQEVIKLKSENSALSESVSYLTTKVKNKVQSNSSESDSIRLS-DKSFIDDKKLLENLLKIYYENPRNEIDDTKTKCELNTSIETSNYKIIANISWDIERLSERKKKNNWAKSNFFYANGDQHKLNLTFWANGYEKSVGNCATIFFRVISSQKDSSLTWPFITKIKIRLTNNYSLESSLELEKLC--------------DLKMPNSN---SFICSDPFDFSYNELFTLGLLRHDCLRIECFV 464
The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TRAF35.041e-1223.10TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF21.912e-1023.31TNF receptor associated factor 2 [Source:HGNC Symb... [more]
TRAF32.287e-1024.37TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF32.287e-1024.37TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF57.794e-1024.02TNF receptor associated factor 5 [Source:HGNC Symb... [more]
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BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf2b4.401e-1121.96Tnf receptor-associated factor 2b [Source:ZFIN;Acc... [more]
traf2b4.401e-1121.96Tnf receptor-associated factor 2b [Source:ZFIN;Acc... [more]
traf2b4.568e-1121.96Tnf receptor-associated factor 2b [Source:ZFIN;Acc... [more]
traf54.164e-920.92Tnf receptor-associated factor 5 [Source:ZFIN;Acc:... [more]
traf2a4.235e-921.66Tnf receptor-associated factor 2a [Source:ZFIN;Acc... [more]
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BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slc12a11.166e-1323.51solute carrier family 12 member 1 [Source:Xenbase;... [more]
slc12a12.775e-1222.80solute carrier family 12 member 1 [Source:Xenbase;... [more]
ssh21.155e-920.72slingshot protein phosphatase 2 [Source:Xenbase;Ac... [more]
sytl26.608e-922.20synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-9... [more]
ssh21.263e-821.97slingshot protein phosphatase 2 [Source:Xenbase;Ac... [more]
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BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Traf22.796e-1122.82TNF receptor-associated factor 2 [Source:MGI Symbo... [more]
Traf23.149e-1122.82TNF receptor-associated factor 2 [Source:MGI Symbo... [more]
Traf51.212e-1021.98TNF receptor-associated factor 5 [Source:MGI Symbo... [more]
Traf51.212e-1021.98TNF receptor-associated factor 5 [Source:MGI Symbo... [more]
Traf32.681e-1024.37TNF receptor-associated factor 3 [Source:MGI Symbo... [more]
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BLAST of TNF receptor-associated factor-2-like protein B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P70191|TRAF5_MOUSE1.424e-1123.29TNF receptor-associated factor 5 OS=Mus musculus O... [more]
sp|P39429|TRAF2_MOUSE1.955e-1022.82TNF receptor-associated factor 2 OS=Mus musculus O... [more]
sp|Q12933|TRAF2_HUMAN9.184e-1023.31TNF receptor-associated factor 2 OS=Homo sapiens O... [more]
sp|Q13114|TRAF3_HUMAN1.098e-924.37TNF receptor-associated factor 3 OS=Homo sapiens O... [more]
sp|Q60803|TRAF3_MOUSE1.875e-924.37TNF receptor-associated factor 3 OS=Mus musculus O... [more]
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BLAST of TNF receptor-associated factor-2-like protein B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
I1ZID82.943e-3734.98TNF receptor associated factor-2 (Fragment) OS=Sch... [more]
T1E1017.181e-3026.02TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
A0A0P7UP013.835e-2025.86TNF receptor-associated factor OS=Scleropages form... [more]
I1ZID71.521e-1829.21TNF receptor associated factor-3 (Fragment) OS=Sch... [more]
A0A452IC944.238e-1724.94TNF receptor-associated factor OS=Gopherus agassiz... [more]
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BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf55.035e-1721.88TNF receptor-associated factor 5 [Source:NCBI gene... [more]
traf2a5.717e-1021.54TNF receptor-associated factor 2-like [Source:NCBI... [more]
traf4a1.671e-922.39TNF receptor associated factor 4 [Source:NCBI gene... [more]
traf2b5.719e-921.75TNF receptor associated factor 2 [Source:NCBI gene... [more]
traf2a1.564e-821.93TNF receptor-associated factor 2-like [Source:NCBI... [more]
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BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO487731.138e-1521.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO494642.700e-1220.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO483941.154e-1120.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO438062.728e-931.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO377507.371e-924.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of TNF receptor-associated factor-2-like protein B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf31.646e-1122.70TNF receptor associated factor 3 [Source:NCBI gene... [more]
ENSORLT00000001369.22.305e-1119.82TNF receptor-associated factor 5 [Source:NCBI gene... [more]
traf2b1.179e-1023.55TNF receptor associated factor 2 [Source:NCBI gene... [more]
traf2b1.313e-1023.55TNF receptor associated factor 2 [Source:NCBI gene... [more]
ENSORLT00000020861.22.270e-1021.19TNF receptor-associated factor 2 [Source:NCBI gene... [more]
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BLAST of TNF receptor-associated factor-2-like protein B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000024592.10.000e+099.30SMESG000024592.1[more]
SMESG000024592.10.000e+095.17SMESG000024592.1[more]
SMESG000024548.11.055e-7631.15SMESG000024548.1[more]
SMESG000024584.19.087e-6930.37SMESG000024584.1[more]
SMESG000024504.17.929e-6129.75SMESG000024504.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023307 ID=SMED30023307|Name=TNF receptor-associated factor-2-like protein B|organism=Schmidtea mediterranea sexual|type=transcript|length=1339bp
GTTTTTTGATTATGCAAGTTCTTGTTAGATCTAATGTCACATTCTGAAAA
GCTTGATTCAATTTTTGAGTTAATAATGAAAAATGACTTCGAAGCTACAG
AAAATATAAGTGAGGATCTCAAATGCATGTTATGTGAAAAGATTTTAATG
AACGCTTATCAGTCCCCTTGCGGCTGCAGCTTCTGTCAGAAATGCATAGA
GGAATTTATTCAAAACGAACCAAAACTCTGTCCAGGAAAATCCGAAGAAT
GCAAACAACAATTTTTAACAAACCTTCAAATTGACTATAAGGCTAATAAT
CGAGTTCAAAAGCTGATTGTAAAATGTCCAGAGAAAACATGCTTGTATAA
ATGCAAATTATCAAACATGGACAACCATTTGAGATTTTGTTCAAAAAAAA
GTGTAAAATGTCCATATTATGATCTTGGCTGCGATGAGGTCGCCATTGCC
ACAGACAAAGTCATTGACCATATCCAATCAGAGATCTATAGTCACAACAG
TATGATCCTTGGCATCAACAACCAAATGAAGCAAAGTATTGAAATGCTTG
CACATCACGAAGAAATACACGAAGAAAATATAACCTCACTCAAAAATAGC
CTAAAAGAAAAGGAAAACCAAATTGAATCTCTAAAAAGAGAGGTCGAAAT
TTTAACCAATAAAATTAATGAAAAAGTTGATCAGAACGCTTTGACGCTTA
ACGCAATATTATTAGAAATGTCAAAGGATTTCGATCAAAAATTAAAACAA
GCTATTTACTCAGTAAATGAAAGTAATGAGAAATATCGGAAAGATATTTT
ATTGAGATTCAATGATCCAGGAAAATACGACGAGGAACATTTTGATTCGG
TTGCGGGATCCATTTTATGGTCCATTGAAAAGATTAATAAATGCCGGAAA
AAGGGTGGTTCAGTCGAGAGCGAATATTTTTATTTGGGTTATAATAAATA
TAAAATGAAATTATTAATGTACGCTAACGGAACTGGCAATGTGACTGGAA
GCGGCCTTAGCATTTATATCTACATTTACCCATGCACAAAGCATTCAAAA
GTCGACTGGCCATTTAAAGGTCTCGTTACAATAAAAGTACTCAACAAGCT
GGATACTTTTGCCAGTGTCAAACAGAGTAAATATTGTATCATTGATAATT
TTGAAGAAGGTCTTGATGATGCAGAAGGCTCTTTATTCATGGACGATTCG
ATTGATTCCTGCGATTACCAATGGGACAACCAATTCGACTTCCTTTACAA
TGAATTATCAGCCTCAGGGGTTCTTGACAATAATATAATAACAGTTGAAT
GCAATGTTGAAATTAAATAAATATTTTTTAAGTTAAAAA
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protein sequence of SMED30023307-orf-1

>SMED30023307-orf-1 ID=SMED30023307-orf-1|Name=SMED30023307-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=429bp
MSHSEKLDSIFELIMKNDFEATENISEDLKCMLCEKILMNAYQSPCGCSF
CQKCIEEFIQNEPKLCPGKSEECKQQFLTNLQIDYKANNRVQKLIVKCPE
KTCLYKCKLSNMDNHLRFCSKKSVKCPYYDLGCDEVAIATDKVIDHIQSE
IYSHNSMILGINNQMKQSIEMLAHHEEIHEENITSLKNSLKEKENQIESL
KREVEILTNKINEKVDQNALTLNAILLEMSKDFDQKLKQAIYSVNESNEK
YRKDILLRFNDPGKYDEEHFDSVAGSILWSIEKINKCRKKGGSVESEYFY
LGYNKYKMKLLMYANGTGNVTGSGLSIYIYIYPCTKHSKVDWPFKGLVTI
KVLNKLDTFASVKQSKYCIIDNFEEGLDDAEGSLFMDDSIDSCDYQWDNQ
FDFLYNELSASGVLDNNIITVECNVEIK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0005164tumor necrosis factor receptor binding
GO:0005515protein binding
GO:0008270zinc ion binding
GO:0004842ubiquitin-protein transferase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0042981regulation of apoptotic process
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0006955immune response
GO:0007165signal transduction
GO:0016567protein ubiquitination
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000421tail
PLANA:0002075pigment cell
PLANA:0002089reproductive organ
PLANA:0002142parenchyma
Vocabulary: INTERPRO
TermDefinition
IPR043211TNF_rcpt-assoc_TRAF
IPR013083Znf_RING/FYVE/PHD
IPR008974TRAF-like
IPR001841Znf_RING
IPR002083MATH/TRAF_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 176..217
NoneNo IPR availablePANTHERPTHR10131:SF129TNF RECEPTOR-ASSOCIATED FACTOR 6coord: 17..119
NoneNo IPR availablePANTHERPTHR10131:SF129TNF RECEPTOR-ASSOCIATED FACTOR 6coord: 110..363
NoneNo IPR availableCDDcd16449RING-HCcoord: 31..67
e-value: 2.10363E-6
score: 42.0693
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 23..99
IPR008974TRAF-likeGENE3DG3DSA:2.60.210.10coord: 264..428
e-value: 1.5E-17
score: 65.7
IPR008974TRAF-likeSUPERFAMILYSSF49599TRAF domain-likecoord: 275..427
IPR008974TRAF-likeSUPERFAMILYSSF49599TRAF domain-likecoord: 93..149
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 12..129
e-value: 1.3E-16
score: 62.6
IPR043211TNF receptor-associated factor TRAFPANTHERPTHR10131TNF RECEPTOR ASSOCIATED FACTORcoord: 17..119
IPR043211TNF receptor-associated factor TRAFPANTHERPTHR10131TNF RECEPTOR ASSOCIATED FACTORcoord: 110..363
IPR002083MATH/TRAF domainPROSITEPS50144MATHcoord: 274..425
score: 11.697
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 31..67
score: 9.391