ANK_REP_REGION domain-containing protein

Overview
NameANK_REP_REGION domain-containing protein
Smed IDSMED30023269
Length (bp)1576
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ANK_REP_REGION domain-containing protein (SMED30023269) t-SNE clustered cells

Violin plots show distribution of expression levels for ANK_REP_REGION domain-containing protein (SMED30023269) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ANK_REP_REGION domain-containing protein (SMED30023269) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ANK_REP_REGION domain-containing protein (SMED30023269) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023269

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30023269SMESG000020728.1 Contig2805GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30023269SMESG000020728.1 Contig2805GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
cephalic gangliaSMED30023269SMESG000020728.1 dd_Smed_v4_4880_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023269SMESG000020728.1 dd_Smed_v4_4880_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: MIB1 (mindbomb E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:21086])

HSP 1 Score: 74.3294 bits (181), Expect = 3.251e-13
Identity = 81/365 (22.19%), Postives = 154/365 (42.19%), Query Frame = 3 
Query:  186 VKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFE---------SMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDL-------------------HPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            V+ +Q   GGW + M E +    TV  +D D  I V   S  +W FN A L         +++   E   +QF+          +  +   ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q  ++    +      DL  ++V     +    KVE   K  D+                   H DIL   + K+N+  +      +  ++  A  D  E  + +V+ + +  LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   DIL  +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  261 VQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQVCYDLERIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVSKVASAGSAISNASGERLSQLLKKL---FETQESGDLNEELVKAA-ANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLL-KQNVDVEAEDKDGDRAVHHAAFGD--EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 617
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: CDKN2D (cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790])

HSP 1 Score: 65.0846 bits (157), Expect = 8.295e-12
Identity = 30/85 (35.29%), Postives = 53/85 (62.35%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKN 1115
            NVQ+ SG +PV+ A   G L+ +K+LV+ GAD+NV D +G  PIH    +GH  +++++       +++++  GL+ L +A Q+ 
Sbjct:   68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE--SDLHRRDARGLTPLELALQRG 150
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: CDKN2D (cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790])

HSP 1 Score: 65.0846 bits (157), Expect = 8.295e-12
Identity = 30/85 (35.29%), Postives = 53/85 (62.35%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKN 1115
            NVQ+ SG +PV+ A   G L+ +K+LV+ GAD+NV D +G  PIH    +GH  +++++       +++++  GL+ L +A Q+ 
Sbjct:   68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE--SDLHRRDARGLTPLELALQRG 150
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: ANKRD63 (ankyrin repeat domain 63 [Source:HGNC Symbol;Acc:HGNC:40027])

HSP 1 Score: 63.929 bits (154), Expect = 2.438e-10
Identity = 29/91 (31.87%), Postives = 55/91 (60.44%), Query Frame = 3 
Query:  855 TLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPE---QINKKNQNGLSLLNIAKQKNN 1118
             +N+++  G+T ++LAC  G L+ V+LLV F  D   AD++GN P+   A  GH  +L ++++ F     ++++ N+ GL+ L +A  + +
Sbjct:   76 AVNLRDERGRTALSLACERGHLDAVQLLVQFSGDPEAADSAGNSPVMWAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAAARGH 166
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Match: PSMD10 (proteasome 26S subunit, non-ATPase 10 [Source:HGNC Symbol;Acc:HGNC:9555])

HSP 1 Score: 59.6918 bits (143), Expect = 4.308e-10
Identity = 32/101 (31.68%), Postives = 53/101 (52.48%), Query Frame = 3 
Query:  840 VIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLL 1142
            + DK      +   +T ++ AC  G  E+V+ L+  G  +N  D++G  P+H  A+ G  +I+  +L +   Q+N  NQNG + L+ A  KN H +   LL
Sbjct:   27 LADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGA-QVNAVNQNGCTPLHYAASKNRHEIAVMLL 126
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 60.077 bits (144), Expect = 3.461e-9
Identity = 34/115 (29.57%), Postives = 62/115 (53.91%), Query Frame = 3 
Query:  771 AVSENSILYFTAIADNDEDKLFQVI--DKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQ 1109
            A + N +      A  D   + Q++  +   +N + N+G TP+++AC  G+L MVK LV+ GAD+     +   P+H  A +GH + + Y+L+      N++   G + L+IA++
Sbjct:  684 AKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASP-NEQTATGQTPLSIAQR 797
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 60.077 bits (144), Expect = 3.461e-9
Identity = 34/115 (29.57%), Postives = 62/115 (53.91%), Query Frame = 3 
Query:  771 AVSENSILYFTAIADNDEDKLFQVI--DKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQ 1109
            A + N +      A  D   + Q++  +   +N + N+G TP+++AC  G+L MVK LV+ GAD+     +   P+H  A +GH + + Y+L+      N++   G + L+IA++
Sbjct:  684 AKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASP-NEQTATGQTPLSIAQR 797
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 60.077 bits (144), Expect = 3.596e-9
Identity = 34/115 (29.57%), Postives = 62/115 (53.91%), Query Frame = 3 
Query:  771 AVSENSILYFTAIADNDEDKLFQVI--DKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQ 1109
            A + N +      A  D   + Q++  +   +N + N+G TP+++AC  G+L MVK LV+ GAD+     +   P+H  A +GH + + Y+L+      N++   G + L+IA++
Sbjct:  684 AKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASP-NEQTATGQTPLSIAQR 797
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 60.077 bits (144), Expect = 3.596e-9
Identity = 34/115 (29.57%), Postives = 62/115 (53.91%), Query Frame = 3 
Query:  771 AVSENSILYFTAIADNDEDKLFQVI--DKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQ 1109
            A + N +      A  D   + Q++  +   +N + N+G TP+++AC  G+L MVK LV+ GAD+     +   P+H  A +GH + + Y+L+      N++   G + L+IA++
Sbjct:  684 AKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASP-NEQTATGQTPLSIAQR 797
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 60.077 bits (144), Expect = 4.013e-9
Identity = 34/115 (29.57%), Postives = 62/115 (53.91%), Query Frame = 3 
Query:  771 AVSENSILYFTAIADNDEDKLFQVI--DKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQ 1109
            A + N +      A  D   + Q++  +   +N + N+G TP+++AC  G+L MVK LV+ GAD+     +   P+H  A +GH + + Y+L+      N++   G + L+IA++
Sbjct:  684 AKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASP-NEQTATGQTPLSIAQR 797
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Match: CG42534 (gene:FBgn0260487 transcript:FBtr0300898)

HSP 1 Score: 69.707 bits (169), Expect = 4.704e-12
Identity = 30/81 (37.04%), Postives = 51/81 (62.96%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIA 1103
            N Q+  G+TP +  C  G+ E +KLL + GA+L + +  G+ P+H  A  G  ++L ++L + P+Q+N  + +G SLL+IA
Sbjct:  409 NRQDRKGRTPAHCGCSKGQFETLKLLKERGANLWLRNAKGDLPLHEAAASGRRELLEWLLAQRPKQVNTTSNDGRSLLHIA 489
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Match: CG42534 (gene:FBgn0260487 transcript:FBtr0309307)

HSP 1 Score: 69.3218 bits (168), Expect = 5.396e-12
Identity = 30/81 (37.04%), Postives = 51/81 (62.96%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIA 1103
            N Q+  G+TP +  C  G+ E +KLL + GA+L + +  G+ P+H  A  G  ++L ++L + P+Q+N  + +G SLL+IA
Sbjct:  284 NRQDRKGRTPAHCGCSKGQFETLKLLKERGANLWLRNAKGDLPLHEAAASGRRELLEWLLAQRPKQVNTTSNDGRSLLHIA 364
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Match: Mbs (gene:FBgn0005536 transcript:FBtr0301473)

HSP 1 Score: 61.2326 bits (147), Expect = 1.982e-9
Identity = 30/85 (35.29%), Postives = 50/85 (58.82%), Query Frame = 3 
Query:  792 LYFTAIADNDEDKLFQVIDKDT-LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQ 1043
            ++  A    D+D++ Q++D+   +N  N  G T ++ AC    L+MV+ LV+ GAD+N  DN G  P+H  A+ G V I  Y+++
Sbjct:   49 VFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVE 133
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Match: Mbs (gene:FBgn0005536 transcript:FBtr0301472)

HSP 1 Score: 60.8474 bits (146), Expect = 2.072e-9
Identity = 30/85 (35.29%), Postives = 50/85 (58.82%), Query Frame = 3 
Query:  792 LYFTAIADNDEDKLFQVIDKDT-LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQ 1043
            ++  A    D+D++ Q++D+   +N  N  G T ++ AC    L+MV+ LV+ GAD+N  DN G  P+H  A+ G V I  Y+++
Sbjct:   49 VFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVE 133
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Match: Mbs (gene:FBgn0005536 transcript:FBtr0308215)

HSP 1 Score: 60.8474 bits (146), Expect = 2.144e-9
Identity = 30/85 (35.29%), Postives = 50/85 (58.82%), Query Frame = 3 
Query:  792 LYFTAIADNDEDKLFQVIDKDT-LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQ 1043
            ++  A    D+D++ Q++D+   +N  N  G T ++ AC    L+MV+ LV+ GAD+N  DN G  P+H  A+ G V I  Y+++
Sbjct:   49 VFLAACLSGDKDEVVQLLDQGADINTANVDGLTALHQACIDDNLDMVEFLVERGADINRQDNEGWTPLHATASCGFVSIARYLVE 133
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:352910])

HSP 1 Score: 72.4034 bits (176), Expect = 7.639e-13
Identity = 84/345 (24.35%), Postives = 145/345 (42.03%), Query Frame = 3 
Query:  135 SYFFNGKKVRVINNKAYVKYIQSSCGGWDESMTECINQICTVLNV--DHDKAINVITASKQKWLFNRAALESSDSKENDETQFESMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKADKKTPPSMVKTFKVGDMLRVSSNEKLIQ----EKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            S F  G  V++  +   +K +Q   G W E+M   + ++  V  +  D D  + V   S   W +N AA+       +  T           E P V  ++ LSQL ++L        +TQ   D      +VK    GD+ +V   E +++    +    C G++ M+     G +  +K      V +E E KD D                    AV   S          DE  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   D+L+ +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  331 SQFMVGDLVQICYDIDRIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTS---WTYNPAAVTKVAPAGSAVTNASGAVLT---ESPSVP-AERLSQLLKKLF-------ETQESGD--INEELVKAAANGDLAKV---EDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLLKHSVDLEAEDKDGD-------------------RAVHHASF--------GDEGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 628
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:352910])

HSP 1 Score: 69.707 bits (169), Expect = 4.699e-12
Identity = 83/385 (21.56%), Postives = 145/385 (37.66%), Query Frame = 3 
Query:  186 VKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFESMHFVNN---------EEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQ------EKQQ---------------------------------YCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            V+ +Q   GGW + M E +    TV  +D D  I V   S  +W FN A L         E +   E   +QF     V            ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q      E Q+                                  C G++ M+     G +  +K      V +E E KD D                    AV   S          DE  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   D+L+ +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  261 VQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANVVRSGEVAAGAEGGSSQFMVGDLVQICYDIDRIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVTKVAPAGSAVTNASGERLSQLLKKLFETQESGDINEELVKAAANGDLAKVEDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLLKHSVDLEAEDKDGD-------------------RAVHHASF--------GDEGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 617
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:352910])

HSP 1 Score: 69.707 bits (169), Expect = 5.603e-12
Identity = 83/385 (21.56%), Postives = 145/385 (37.66%), Query Frame = 3 
Query:  186 VKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFESMHFVNN---------EEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQ------EKQQ---------------------------------YCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            V+ +Q   GGW + M E +    TV  +D D  I V   S  +W FN A L         E +   E   +QF     V            ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q      E Q+                                  C G++ M+     G +  +K      V +E E KD D                    AV   S          DE  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   D+L+ +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  261 VQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANVVRSGEVAAGAEGGSSQFMVGDLVQICYDIDRIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVTKVAPAGSAVTNASGERLSQLLKKLFETQESGDINEELVKAAANGDLAKVEDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLLKHSVDLEAEDKDGD-------------------RAVHHASF--------GDEGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 617
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: bcl3 (BCL3 transcription coactivator [Source:ZFIN;Acc:ZDB-GENE-061013-1])

HSP 1 Score: 64.3142 bits (155), Expect = 1.252e-10
Identity = 44/147 (29.93%), Postives = 73/147 (49.66%), Query Frame = 3 
Query:  774 VSENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRF----PEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEI 1202
            V EN  L    I      ++F+   KD L++ NN  +TP++LA    +  +VK L+D G+D    D +G    H C   G  + L+ IL+ +    P  +  +N  GL+ L++A Q  +  L   LL S  + +  +SQ +T S ++
Sbjct:  222 VQENRALVVWLI------EIFRCAHKD-LDIYNNLRQTPLHLAVITHQPAVVKALLDAGSDPGALDRNGQTAQHLCCEHGEAECLSIILRHYSHNNPSHVEIRNYEGLTPLHLAVQNGDQTLTGILLDSGAEINAGVSQFITISSDM 361
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Match: cdkn2d (cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) [Source:ZFIN;Acc:ZDB-GENE-110316-1])

HSP 1 Score: 59.6918 bits (143), Expect = 3.372e-10
Identity = 27/59 (45.76%), Postives = 39/59 (66.10%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYI 1037
            NVQ+ SG TP + A   G LE +++LVD GA +NV D+SG  P+H    +GH D++ Y+
Sbjct:   69 NVQDRSGVTPAHDAARTGFLETLRVLVDGGASVNVPDHSGALPLHIAVREGHWDVVEYL 127
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Match: mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:100170182])

HSP 1 Score: 70.4774 bits (171), Expect = 4.519e-12
Identity = 84/345 (24.35%), Postives = 145/345 (42.03%), Query Frame = 3 
Query:  135 SYFFNGKKVRVINNKAYVKYIQSSCGGWDESMTECINQICTVLNV--DHDKAINVITASKQKWLFNRAALESSDSKENDETQFESMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKADKKTPPSMVKTFKVGDMLRVSSNEKLIQEK----QQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            S F  G  V++  +   +K +Q   G W E+M   + ++  V  +  D+D  + V   S   W +N AA+    S  +  +         N      K+ + LSQL ++L        +TQ   D      +VK    GD+ +V   E L++ +       C G++ M+     G +  +K      V VE E KD D                           ++  A  D  E  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   DIL  +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  331 SPFQVGDLVQICYDLERIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDNDLKVEVCGTS---WTYNPAAVSRVASVGSAISNATGGKLDYN---LSFKLVERLSQLLKKLF-------ETQESGDLN--EELVKAAANGDVAKV---EDLLKRQDVDVNGQCAGHTAMQAASQNGHVDILKLLLKHSVDVEAEDKDGD-------------------------RAVHHAAFGD--EGTVVEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKKLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 629
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Match: mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:100170182])

HSP 1 Score: 67.3958 bits (163), Expect = 3.476e-11
Identity = 83/345 (24.06%), Postives = 144/345 (41.74%), Query Frame = 3 
Query:  135 SYFFNGKKVRVINNKAYVKYIQSSCGGWDESMTECINQICTVLNV--DHDKAINVITASKQKWLFNRAALESSDSKENDETQFESMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKADKKTPPSMVKTFKVGDMLRVSSNEKLIQEK----QQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            S F  G  V++  +   +K +Q   G W E+M   + ++  V  +  D+D  + V   S   W +N AA+    S  +          ++N         + LSQL ++L        +TQ   D      +VK    GD+ +V   E L++ +       C G++ M+     G +  +K      V VE E KD D                           ++  A  D  E  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   DIL  +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  331 SPFQVGDLVQICYDLERIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDNDLKVEVCGTS---WTYNPAAVSRVASVGS---------AISN------ATGERLSQLLKKLF-------ETQESGDLN--EELVKAAANGDVAKV---EDLLKRQDVDVNGQCAGHTAMQAASQNGHVDILKLLLKHSVDVEAEDKDGD-------------------------RAVHHAAFGD--EGTVVEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKKLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 617
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Match: PPP1R12A (protein phosphatase 1 regulatory subunit 12A [Source:NCBI gene;Acc:100493563])

HSP 1 Score: 64.6994 bits (156), Expect = 2.681e-10
Identity = 38/140 (27.14%), Postives = 73/140 (52.14%), Query Frame = 3 
Query:  696 GKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT-LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQK 1112
            G + DL P ++          KK     ++  ++  A +  D D++ +++D+   +N  N  G T ++ AC    ++MVK LV+ GA +N  DN G  P+H  ++ G++DI  Y++ +    +   N  G + L+IA+++
Sbjct:   19 GSETDLEPHVIKR--------KKTKVKFDDGAVFLAACSSGDTDEVLKLLDRGADINYANVDGLTALHQACIDDNIDMVKFLVEHGAGINQPDNEGWIPLHAASSCGYLDIAEYLISKGA-SVGVVNSEGDTPLDIAEEE 149
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Match: cpsf1 (cleavage and polyadenylation specific factor 1 [Source:Xenbase;Acc:XB-GENE-5881751])

HSP 1 Score: 62.7734 bits (151), Expect = 4.051e-10
Identity = 44/140 (31.43%), Postives = 68/140 (48.57%), Query Frame = 3 
Query:  747 ENLPKKE-PAVSENSILYFTAIADNDE--DKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNID 1157
            ENLP+K  P V E   L+  A   N     +L Q    + ++ ++  G T ++ A   G L  VKLL+  GA L+  D SG  P+H+ A+ GH  +   +LQR         + GL+ L++A    +  +   LL  N+D
Sbjct:   23 ENLPEKSCPGVKEWKTLHLAAWNGNTRLVKQLLQ--QGEAVDSRDGLGWTSLHCAAANGHLSTVKLLIQRGALLSCQDGSGCTPLHHAAHNGHTHLCELLLQRGANP-GATTKGGLTPLHLAASNGHTLITQLLLKQNLD 159
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Match: PPP1R12A (protein phosphatase 1 regulatory subunit 12A [Source:NCBI gene;Acc:100493563])

HSP 1 Score: 63.929 bits (154), Expect = 4.236e-10
Identity = 38/140 (27.14%), Postives = 73/140 (52.14%), Query Frame = 3 
Query:  696 GKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT-LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQK 1112
            G + DL P ++          KK     ++  ++  A +  D D++ +++D+   +N  N  G T ++ AC    ++MVK LV+ GA +N  DN G  P+H  ++ G++DI  Y++ +    +   N  G + L+IA+++
Sbjct:   19 GSETDLEPHVIKR--------KKTKVKFDDGAVFLAACSSGDTDEVLKLLDRGADINYANVDGLTALHQACIDDNIDMVKFLVEHGAGINQPDNEGWIPLHAASSCGYLDIAEYLISKGA-SVGVVNSEGDTPLDIAEEE 149
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:MGI Symbol;Acc:MGI:2443157])

HSP 1 Score: 70.8626 bits (172), Expect = 2.471e-12
Identity = 79/357 (22.13%), Postives = 150/357 (42.02%), Query Frame = 3 
Query:  210 GGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFE---------SMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDL-------------------HPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            GGW + M E +    TV  +D D  I V   S  +W FN A L         +++   E   +QF+          +  +   ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q  ++    +      DL  ++V     +    KVE   K  D+                   H DIL   + K+N+  +      +  ++  A  D  E  + +V+ + +  LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   DIL  +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  269 GGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQVCYDLERIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVSKVAPAGSAISNASGERLSQLLKKL---FETQESGDLNEELVKAA-ANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLL-KQNVDVEAEDKDGDRAVHHAAFGD--EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 617

HSP 2 Score: 52.373 bits (124), Expect = 1.412e-6
Identity = 58/246 (23.58%), Postives = 111/246 (45.12%), Query Frame = 3 
Query:  858 LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINK--------KNQNGLSL-LNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEISLFSPPT---TITRTNEDE-NSEFPTRYPAITISSSLMDPPRDEFDTIEVPXXXXXXXXXXXXXXXYTMNSTPVKNECMICRDGHLNTAFVQCGHLA-CNVCADRIFRCHICQAEIEKKIFI 1553
            L++QN + +T ++LA      ++V+LLV  GA L++ D  G+ P+H  A + H       LQ   + + K        KN   + L    A++K+   +  FL A+  D S R  +  +    + L   P+    + + ++++ + +  +R P++  + S         +T+E                           ECM+C D   +T F  CGH+A C++C+ R+ +C IC+ +++ +  I
Sbjct:  659 LDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHE-ALRHHTLSQLRQLQDM-QDVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQS---PLDLCPDPSLCKALAKCHKEKVSGQVGSRSPSMISNDS---------ETLE---------------------------ECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSRTKI 863
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:MGI Symbol;Acc:MGI:2443157])

HSP 1 Score: 70.8626 bits (172), Expect = 2.471e-12
Identity = 79/357 (22.13%), Postives = 150/357 (42.02%), Query Frame = 3 
Query:  210 GGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFE---------SMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDL-------------------HPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            GGW + M E +    TV  +D D  I V   S  +W FN A L         +++   E   +QF+          +  +   ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q  ++    +      DL  ++V     +    KVE   K  D+                   H DIL   + K+N+  +      +  ++  A  D  E  + +V+ + +  LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   DIL  +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  269 GGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQVCYDLERIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVSKVAPAGSAISNASGERLSQLLKKL---FETQESGDLNEELVKAA-ANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLL-KQNVDVEAEDKDGDRAVHHAAFGD--EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 617

HSP 2 Score: 52.373 bits (124), Expect = 1.412e-6
Identity = 58/246 (23.58%), Postives = 111/246 (45.12%), Query Frame = 3 
Query:  858 LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINK--------KNQNGLSL-LNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEISLFSPPT---TITRTNEDE-NSEFPTRYPAITISSSLMDPPRDEFDTIEVPXXXXXXXXXXXXXXXYTMNSTPVKNECMICRDGHLNTAFVQCGHLA-CNVCADRIFRCHICQAEIEKKIFI 1553
            L++QN + +T ++LA      ++V+LLV  GA L++ D  G+ P+H  A + H       LQ   + + K        KN   + L    A++K+   +  FL A+  D S R  +  +    + L   P+    + + ++++ + +  +R P++  + S         +T+E                           ECM+C D   +T F  CGH+A C++C+ R+ +C IC+ +++ +  I
Sbjct:  659 LDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHE-ALRHHTLSQLRQLQDM-QDVGKVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQS---PLDLCPDPSLCKALAKCHKEKVSGQVGSRSPSMISNDS---------ETLE---------------------------ECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSRTKI 863
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Cdkn2d (cyclin dependent kinase inhibitor 2D [Source:MGI Symbol;Acc:MGI:105387])

HSP 1 Score: 65.0846 bits (157), Expect = 5.695e-12
Identity = 33/94 (35.11%), Postives = 59/94 (62.77%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQ-INKKNQNGLSLLNIAKQKNNHRLETFL 1139
            NVQ+ SG +PV+ A   G L+ +K+LV+ GAD+N  D++G+ PIH    +GH  +++++    PE  ++ ++ +GL+ L +A+Q+    L   L
Sbjct:   68 NVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFL---APESDLHHRDASGLTPLELARQRGAQNLMDIL 158
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Cdkn2d (cyclin dependent kinase inhibitor 2D [Source:MGI Symbol;Acc:MGI:105387])

HSP 1 Score: 65.0846 bits (157), Expect = 5.884e-12
Identity = 33/94 (35.11%), Postives = 59/94 (62.77%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQ-INKKNQNGLSLLNIAKQKNNHRLETFL 1139
            NVQ+ SG +PV+ A   G L+ +K+LV+ GAD+N  D++G+ PIH    +GH  +++++    PE  ++ ++ +GL+ L +A+Q+    L   L
Sbjct:   68 NVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFL---APESDLHHRDASGLTPLELARQRGAQNLMDIL 158
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Match: Ankrd63 (ankyrin repeat domain 63 [Source:MGI Symbol;Acc:MGI:2686183])

HSP 1 Score: 62.003 bits (149), Expect = 6.932e-10
Identity = 28/91 (30.77%), Postives = 54/91 (59.34%), Query Frame = 3 
Query:  855 TLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPE---QINKKNQNGLSLLNIAKQKNN 1118
             +N+++  G+T ++LAC  G L+ V+LLV F  D    D++GN P+   A  GH  +L ++++ F     ++++ N+ GL+ L +A  + +
Sbjct:   76 AVNLRDERGRTALSLACERGHLDAVQLLVQFSGDPEATDSAGNSPVMWAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAASRGH 166
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q86YT6|MIB1_HUMAN (E3 ubiquitin-protein ligase MIB1 OS=Homo sapiens OX=9606 GN=MIB1 PE=1 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 1.561e-12
Identity = 81/365 (22.19%), Postives = 154/365 (42.19%), Query Frame = 3 
Query:  186 VKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFE---------SMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDL-------------------HPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            V+ +Q   GGW + M E +    TV  +D D  I V   S  +W FN A L         +++   E   +QF+          +  +   ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q  ++    +      DL  ++V     +    KVE   K  D+                   H DIL   + K+N+  +      +  ++  A  D  E  + +V+ + +  LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   DIL  +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  261 VQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQVCYDLERIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVSKVASAGSAISNASGERLSQLLKKL---FETQESGDLNEELVKAA-ANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLL-KQNVDVEAEDKDGDRAVHHAAFGD--EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 617
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q80SY4|MIB1_MOUSE (E3 ubiquitin-protein ligase MIB1 OS=Mus musculus OX=10090 GN=Mib1 PE=1 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 1.728e-11
Identity = 79/357 (22.13%), Postives = 150/357 (42.02%), Query Frame = 3 
Query:  210 GGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFE---------SMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDL-------------------HPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            GGW + M E +    TV  +D D  I V   S  +W FN A L         +++   E   +QF+          +  +   ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q  ++    +      DL  ++V     +    KVE   K  D+                   H DIL   + K+N+  +      +  ++  A  D  E  + +V+ + +  LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   DIL  +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  269 GGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQVCYDLERIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVSKVAPAGSAISNASGERLSQLLKKL---FETQESGDLNEELVKAA-ANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLL-KQNVDVEAEDKDGDRAVHHAAFGD--EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 617
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q804S5|MIB1_DANRE (E3 ubiquitin-protein ligase mib1 OS=Danio rerio OX=7955 GN=mib1 PE=1 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 3.547e-11
Identity = 83/385 (21.56%), Postives = 145/385 (37.66%), Query Frame = 3 
Query:  186 VKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFESMHFVNN---------EEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQ------EKQQ---------------------------------YCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            V+ +Q   GGW + M E +    TV  +D D  I V   S  +W FN A L         E +   E   +QF     V            ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q      E Q+                                  C G++ M+     G +  +K      V +E E KD D                    AV   S          DE  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   D+L+ +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  261 VQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANVVRSGEVAAGAEGGSSQFMVGDLVQICYDIDRIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVTKVAPAGSAVTNASGERLSQLLKKLFETQESGDINEELVKAAANGDLAKVEDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLLKHSVDLEAEDKDGD-------------------RAVHHASF--------GDEGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 617
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q60773|CDN2D_MOUSE (Cyclin-dependent kinase 4 inhibitor D OS=Mus musculus OX=10090 GN=Cdkn2d PE=1 SV=2)

HSP 1 Score: 65.0846 bits (157), Expect = 3.984e-11
Identity = 33/94 (35.11%), Postives = 59/94 (62.77%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQ-INKKNQNGLSLLNIAKQKNNHRLETFL 1139
            NVQ+ SG +PV+ A   G L+ +K+LV+ GAD+N  D++G+ PIH    +GH  +++++    PE  ++ ++ +GL+ L +A+Q+    L   L
Sbjct:   68 NVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFL---APESDLHHRDASGLTPLELARQRGAQNLMDIL 158
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|P55273|CDN2D_HUMAN (Cyclin-dependent kinase 4 inhibitor D OS=Homo sapiens OX=9606 GN=CDKN2D PE=1 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 3.984e-11
Identity = 30/85 (35.29%), Postives = 53/85 (62.35%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKN 1115
            NVQ+ SG +PV+ A   G L+ +K+LV+ GAD+NV D +G  PIH    +GH  +++++       +++++  GL+ L +A Q+ 
Sbjct:   68 NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE--SDLHRRDARGLTPLELALQRG 150
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A4Z2HRF3 (E3 ubiquitin-protein ligase mib1 OS=Liparis tanakae OX=230148 GN=mib1_2 PE=4 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 5.311e-14
Identity = 85/351 (24.22%), Postives = 149/351 (42.45%), Query Frame = 3 
Query:  186 VKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFESMHFVNNEEK----PDVKISDELSQLTERLAAIEQVKPD---TQNKADKKTPPSMVKTFKV---GD----MLRVSSNEKLIQ----------EKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLET 1133
            V+ +Q   GGW + M E +    TV  +D D  I V   S  +W FN A L         E +   E   +QF ++  V   ++     D+K+    +  T   AA+ ++ P      N + ++    + K F+    GD    +++ ++N  L +          +    C G++ M+     G +  +K      V +E E KD D                    AV   S          DE  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   D+L+ +L+   + +   N NG + L+ A  + N R ET
Sbjct:  261 VQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANAVRSGEVAAGAEGGTSQFVTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVTKIAPSGSAVSNASGERLSQLLKKLFETQESGDINEELVKAAANGDLAKVEDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLLKHNVDLEAEDKDGDR-------------------AVHHASF--------GDEGSVIEVLQRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGAD-VTITNNNGFNALHHAALRGNPRYET 583
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A3R7N7Q1 (Death-associated protein kinase 1 OS=Penaeus vannamei OX=6689 GN=C7M84_001810 PE=4 SV=1)

HSP 1 Score: 80.1073 bits (196), Expect = 2.277e-12
Identity = 36/93 (38.71%), Postives = 60/93 (64.52%), Query Frame = 3 
Query:  825 DKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIA 1103
            ++LF +     +N+ N  G++ ++LAC LG+LE V+ LV  G DLN  D  G+ P+H  A +GH  ++ Y++++   QIN +N+NG S L++A
Sbjct:  162 EELFNMAQNIDVNMANKHGESAIHLACGLGQLEAVQFLVKKGGDLNATDAQGDTPLHWAARQGHAQVIAYLIEQG-SQINAQNKNGESCLHVA 253
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: S9WGW3 (E3 ubiquitin-protein ligase MIB1 OS=Camelus ferus OX=419612 GN=CB1_001599005 PE=4 SV=1)

HSP 1 Score: 80.4925 bits (197), Expect = 4.144e-12
Identity = 86/340 (25.29%), Postives = 143/340 (42.06%), Query Frame = 3 
Query:  186 VKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFESMHFVNNEEKPDVKISDELSQLTERLAA--IEQVKP---DTQNKADKKTPPSMVKTFKVGDMLRVSSNEKLIQ----EKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            V+ +Q   GGW + M E +    TV  +D D  I V   S  +W FN A L         +++   E   +QF+    V       V    E  +L +R      E + P   +TQ   D      +VK    GD+ +V   E L++    +    C G++ M+     G +  +K    + V VE E KD D                           ++  A  D  E  + +V+ + +  LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   DIL  +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  176 VQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQ------VCYDLERIKLLQRGHGEWAEAMLPKLFETQESGDLN--EELVKAAANGDVAKV---EDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGD-------------------------RAVHHAAFGD--EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 476
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A3L7I1W5 (MIB1 OS=Cricetulus griseus OX=10029 GN=CgPICR_015285 PE=4 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 4.903e-12
Identity = 78/350 (22.29%), Postives = 148/350 (42.29%), Query Frame = 3 
Query:  186 VKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFE---------SMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNK-------------ADKKTPPSMVKTFKVGDM----LRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHR 1124
            V+ +Q   GGW + M E +    TV  +D D  I V   S  +W FN A L         +++   E   +QF+          +  +   ++   + ++ +     ++  ++Q+  D+  K             A  K    + +T + GD+    ++ ++N  + +   Q C G++ M+     G +  +K    + V VE E KD D                           ++  A  D  E  + +V+ + +  LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   DIL  +L+   + +   N NG + L+ A  + N R
Sbjct:  143 VQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQVCYDLERIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVSKLLKKLFETQESGDLNEELVKAAANGDVAKVNGQ-CAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGD-------------------------RAVHHAAFGD--EGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD-VTITNNNGFNALHHAALRGNPR 463
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Match: A0A5B7EPJ4 (Death-associated protein kinase 1 OS=Portunus trituberculatus OX=210409 GN=DAPK1_0 PE=4 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 1.585e-11
Identity = 42/133 (31.58%), Postives = 75/133 (56.39%), Query Frame = 3 
Query:  726 LDYPVDKENLPKKEPAVSENSILYFTAIADNDED-------KLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIA 1103
            LD+P  +  L K EP + ++S    +A+    E+       KLF V     +N+ N  G++ ++L+C LG+L+ ++ LV  G  +   D  G+ P+H  A +GH  I+ Y++++   QIN +N+NG + L++A
Sbjct:  117 LDFP--RAQLEKLEPEMLQDSSFVLSAMVAAVEEGNLPGLEKLFTVAQNIDVNMANKHGESAIHLSCGLGQLDALRFLVKKGGGIEATDAQGDTPLHWAARQGHAHIIAYLIEQ-GAQINTQNKNGETCLHVA 246
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:352910])

HSP 1 Score: 65.4698 bits (158), Expect = 8.906e-11
Identity = 76/353 (21.53%), Postives = 145/353 (41.08%), Query Frame = 3 
Query:  210 GGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFESMHFVNN---------EEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQ------EKQQYCGGYSKMRMRDLIGKIVTVKH--------YSVKCV-KVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            GGW + M E +    TV  +D D  I V   S  +W FN A L         E +   E   +QF     V            ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q      E Q+      ++      G +  V+          + +C      +    + H D+L   + K N+  +      +  ++  A  D  E  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   D+L+ +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  269 GGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANVARSGEVAAGAEGGSSQFMVGDLVQICYDIDRIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVTKVAPAGSAVTNASGERLSQLLKKLFETQESGDINEELVKAAANGDLAKVEDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLL-KHNVDLEAEDKDGDRAVHHAAFGD--EGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 617
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:352910])

HSP 1 Score: 65.4698 bits (158), Expect = 9.281e-11
Identity = 76/353 (21.53%), Postives = 145/353 (41.08%), Query Frame = 3 
Query:  210 GGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFESMHFVNN---------EEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQ------EKQQYCGGYSKMRMRDLIGKIVTVKH--------YSVKCVK-VEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            GGW + M E +    TV  +D D  I V   S  +W FN A L         E +   E   +QF     V            ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q      E Q+      ++      G +  V+          + +C      +    + H D+L   + K N+  +      +  ++  A  D  E  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   D+L+ +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  266 GGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANVARSGEVAAGAEGGSSQFMVGDLVQICYDIDRIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVTKVAPAGSAVTNASGERLSQLLKKLFETQESGDINEELVKAAANGDLAKVEDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLL-KHNVDLEAEDKDGDRAVHHAAFGD--EGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 614
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: tnksb (tankyrase-1 [Source:NCBI gene;Acc:103045612])

HSP 1 Score: 65.0846 bits (157), Expect = 1.194e-10
Identity = 38/114 (33.33%), Postives = 62/114 (54.39%), Query Frame = 3 
Query:  852 DTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVT 1187
            D +N ++  G+  TP++LA     LE+ + L++ GAD+N  D  G  P+HN A+ GHVDI   +L +F   +N  ++   + L+ A QK   +L   LLA   D + +  +  T
Sbjct:  735 DNINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA-LLIKFNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQT 847

HSP 2 Score: 56.9954 bits (136), Expect = 4.282e-8
Identity = 34/124 (27.42%), Postives = 64/124 (51.61%), Query Frame = 3 
Query:  798 FTAIADNDEDKLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSS 1163
              A    +EDKL  ++    +N   + G+  TP++LA    ++ +V+LL+ +GAD++  D  G  P+HN  + GH ++ T +L +    +N  +    + L+ A  KN   + + LL+   D +
Sbjct:  238 LEAARSGNEDKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQYGADVHAKDKGGLVPLHNACSYGHYEV-TELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPT 360

HSP 3 Score: 55.8398 bits (133), Expect = 9.772e-8
Identity = 39/124 (31.45%), Postives = 65/124 (52.42%), Query Frame = 3 
Query:  738 VDKENLPKKEPAVSENSILYFTAIADNDE--DKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIA 1103
            VD  N+  K+ A  +++ L+F A     +  + L Q      ++ +++ G  P++ AC  G  E+V LL+  GAD N  DN    P+H  A KG +D+   +LQ   +  N +N +G S L++A
Sbjct:  100 VDAANVNAKDMAGRKSTPLHFAAGFGRKDVVEHLLQT--GANVHSRDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP-NIRNTDGKSALDLA 220

HSP 4 Score: 50.0618 bits (118), Expect = 5.619e-6
Identity = 35/143 (24.48%), Postives = 66/143 (46.15%), Query Frame = 3 
Query:  747 ENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTR 1169
            EN+P +    S+    +  A    D D + Q+     +N ++  G+  TP++ A    ++ +V+ L+  GAD++  D  G  P+HN  + GH ++   +L R    +N  +    + L+ A  K  + +   LL    D S +
Sbjct:  550 ENVPARN---SDVDYRFLEAAKAGDLDTVKQLCSPQNVNCRDLEGRHSTPLHFAAGYNRVAVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEV-AELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPSKK 688
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: tnksb (tankyrase-1 [Source:NCBI gene;Acc:103045612])

HSP 1 Score: 65.0846 bits (157), Expect = 1.249e-10
Identity = 38/114 (33.33%), Postives = 62/114 (54.39%), Query Frame = 3 
Query:  852 DTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVT 1187
            D +N ++  G+  TP++LA     LE+ + L++ GAD+N  D  G  P+HN A+ GHVDI   +L +F   +N  ++   + L+ A QK   +L   LLA   D + +  +  T
Sbjct:  742 DNINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA-LLIKFNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQT 854

HSP 2 Score: 55.8398 bits (133), Expect = 1.013e-7
Identity = 39/124 (31.45%), Postives = 65/124 (52.42%), Query Frame = 3 
Query:  738 VDKENLPKKEPAVSENSILYFTAIADNDE--DKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIA 1103
            VD  N+  K+ A  +++ L+F A     +  + L Q      ++ +++ G  P++ AC  G  E+V LL+  GAD N  DN    P+H  A KG +D+   +LQ   +  N +N +G S L++A
Sbjct:  100 VDAANVNAKDMAGRKSTPLHFAAGFGRKDVVEHLLQT--GANVHSRDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP-NIRNTDGKSALDLA 220

HSP 3 Score: 54.299 bits (129), Expect = 3.201e-7
Identity = 34/131 (25.95%), Postives = 64/131 (48.85%), Query Frame = 3 
Query:  798 FTAIADNDEDKLFQVIDKDTLNVQNNSGK---------TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSS 1163
              A    +EDKL  ++    +N   + G+         TP++LA    ++ +V+LL+ +GAD++  D  G  P+HN  + GH ++ T +L +    +N  +    + L+ A  KN   + + LL+   D +
Sbjct:  238 LEAARSGNEDKLMALLTPLNVNCHASDGRKSTSQKMLSTPLHLAAGYNRVRIVQLLLQYGADVHAKDKGGLVPLHNACSYGHYEV-TELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPT 367

HSP 4 Score: 50.0618 bits (118), Expect = 6.288e-6
Identity = 35/143 (24.48%), Postives = 66/143 (46.15%), Query Frame = 3 
Query:  747 ENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTR 1169
            EN+P +    S+    +  A    D D + Q+     +N ++  G+  TP++ A    ++ +V+ L+  GAD++  D  G  P+HN  + GH ++   +L R    +N  +    + L+ A  K  + +   LL    D S +
Sbjct:  557 ENVPARN---SDVDYRFLEAAKAGDLDTVKQLCSPQNVNCRDLEGRHSTPLHFAAGYNRVAVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEV-AELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPSKK 695
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Match: nfkbie (NFKB inhibitor epsilon [Source:NCBI gene;Acc:103021553])

HSP 1 Score: 63.5438 bits (153), Expect = 1.520e-10
Identity = 44/135 (32.59%), Postives = 72/135 (53.33%), Query Frame = 3 
Query:  831 LFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIH--------NCANKGHVDIL-TYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEISL 1208
            L  ++ K+ L++QNN  +TP++LA  L + ++VKLL + GA L + D  GN P+H         CAN+  +D   T ++Q F  Q    N  GL+ L++A     HRL   L+   +D + +   S   +L I++
Sbjct:  134 LISILPKEVLDIQNNLYQTPMHLAVYLNQPDVVKLLKENGACLELQDQDGNTPLHVACEHGRLECANEMILDSSPTKLVQVFETQ----NWRGLTCLHVATLHKQHRLMKLLMKKGVDLNIQEGTSGKTALHIAV 264
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009608.1 (pep scaffold:Pmarinus_7.0:GL477242:23155:61557:-1 gene:ENSPMAG00000008655.1 transcript:ENSPMAT00000009608.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.929 bits (154), Expect = 6.229e-11
Identity = 36/116 (31.03%), Postives = 65/116 (56.03%), Query Frame = 3 
Query:  828 KLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTR 1169
            ++ ++   + +N +++ G+  TP++LA     LE+ + L++ GAD+N  D  G  P+HN A+ GHVDI   +L ++   +N  ++   + L+ A QK   +L   LLA   D S +
Sbjct:  784 RVQKLCSGENVNCRDSQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA-LLIKYSACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPSMK 898

HSP 2 Score: 54.299 bits (129), Expect = 5.615e-8
Identity = 33/122 (27.05%), Postives = 63/122 (51.64%), Query Frame = 3 
Query:  804 AIADNDEDKLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSS 1163
            A    +E+KL  ++    +N   + G+  TP++LA    ++ +V+LL+  GAD++  D  G  P+HN  + GH ++ T +L +    +N  +    + L+ A  KN   + + LL+   D +
Sbjct:  307 AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEV-TELLVKHGASVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPT 427

HSP 3 Score: 50.0618 bits (118), Expect = 1.140e-6
Identity = 27/83 (32.53%), Postives = 47/83 (56.63%), Query Frame = 3 
Query:  858 LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAK 1106
            ++ +++ G  P++ AC  G  E+V LL+  GAD N  DN    P+H  A KG +D+   +LQ   +    +N +G + L++A+
Sbjct:  207 VHARDDGGLIPLHNACSFGHAEVVNLLLRQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP-GIRNTDGKTALDLAE 288

HSP 4 Score: 49.2914 bits (116), Expect = 2.425e-6
Identity = 36/157 (22.93%), Postives = 74/157 (47.13%), Query Frame = 3 
Query:  798 FTAIADNDEDKLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEISLFSPPTTITRTNEDENSEF 1262
            F A  + D  ++ +++    +N ++ +G+  TP++ A   G+ ++V+ L+  GA+++  D+ G  P+HN  + GH +++  +L++  +   + N N  + L+ A  K    +   LL    D   R +   T    + L  P      T E +  E 
Sbjct:  152 FEACRNGDVGRVKRLVSPLNVNARDTTGRKSTPLHFAAGFGRKDVVEHLLQNGANVHARDDGGLIPLHNACSFGHAEVVNLLLRQGADPNARDNWN-YTPLHEAAIKGKIDVCIVLLQHGADPGIRNTDGKT---ALDLAEPTAKAVLTGEYKKDEL 304

HSP 5 Score: 47.7506 bits (112), Expect = 5.712e-6
Identity = 28/86 (32.56%), Postives = 49/86 (56.98%), Query Frame = 3 
Query:  858 LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKN 1115
            ++ ++  G  P++ AC  G  E+ +LLV  GA +NVAD     P+H  A KG  +I   +L+   +   KKN++G + L++ K+ +
Sbjct:  676 VHAKDKGGLVPLHNACSYGHYEVAELLVKRGAVVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP-TKKNRDGNTPLDLVKEGD 760

HSP 6 Score: 47.7506 bits (112), Expect = 5.761e-6
Identity = 30/124 (24.19%), Postives = 60/124 (48.39%), Query Frame = 3 
Query:  804 AIADNDEDKLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTR 1169
            A    D D + Q+    T+N ++  G+  TP++ A    ++ +V+ L+  GAD++  D  G  P+HN  + GH ++   +++R    +N  +    + L+ A  K  + +   LL    D + +
Sbjct:  623 AAKAGDLDTVKQLCTTQTVNCRDMEGRHSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKRG-AVVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKK 745
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 7.782e-10
Identity = 34/139 (24.46%), Postives = 76/139 (54.68%), Query Frame = 3 
Query:  771 AVSENSI--LYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLL--ASNIDSSTRIS 1175
            A  +N +  L+  +  DN +  L  +    + +    +G TP+++A    +LE+   L+++GA+ N     G  P+H  A +GH D+ + +L R+ + +N   ++GLS L++A Q++   +   L+   ++++++T++ 
Sbjct:  298 AAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYAD-VNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLG 435

HSP 2 Score: 53.1434 bits (126), Expect = 1.483e-7
Identity = 26/94 (27.66%), Postives = 52/94 (55.32%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLL 1142
            +   ++G TP+++A   G  ++  +L++ GA L V    G  P+H  +  G +++ + +LQRF    +   +NGL+ L++A   +N ++   LL
Sbjct:  231 DAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASP-DAAGKNGLTPLHVASHYDNQKVALLLL 323

HSP 3 Score: 52.373 bits (124), Expect = 2.297e-7
Identity = 36/127 (28.35%), Postives = 58/127 (45.67%), Query Frame = 3 
Query:  858 LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKN-----------NHRLETFLLASNIDSSTRISQSVTNSLEIS 1205
            +N     G TP+ +AC  G ++MV  L+  GAD+N    +G  P+H  A +GH  I+  +L +   + N    NG + L IA++                  T    SN  S   + +++T  LE+S
Sbjct:  428 VNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLL-KCGARPNDVTVNGNTALAIARRLGYISVVDTLKVVTEETITSTTVSNPSSRVNVPETMTEVLEVS 553

HSP 4 Score: 51.9878 bits (123), Expect = 2.921e-7
Identity = 33/123 (26.83%), Postives = 61/123 (49.59%), Query Frame = 3 
Query:  774 VSENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLL 1142
            V   + L+  A A   E     + +   ++ +    +TP+++A  LGKLE+V+LL+   A  + A ++G  P+H  A +GH D+ T IL      +    + G + L++A +     + + LL
Sbjct:  169 VRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDV-TAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLL 290

HSP 5 Score: 48.9062 bits (115), Expect = 2.737e-6
Identity = 30/109 (27.52%), Postives = 58/109 (53.21%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLL--ASNIDSSTRISQS 1181
            NV+  +G TP+++AC   ++ +++LL+ +GA +     SG  P+H  A  G+++I+  +LQ      N  N  G + L++A +     +   LL   + +D+  R  Q+
Sbjct:   99 NVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASP-NATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQT 206
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007449.1 (pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007449.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.077 bits (144), Expect = 1.008e-9
Identity = 34/141 (24.11%), Postives = 77/141 (54.61%), Query Frame = 3 
Query:  771 AVSENSI--LYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLL--ASNIDSSTRISQS 1181
            A  +N +  L+  +  DN +  L  +    + +    +G TP+++A    +LE+   L+++GA+ N     G  P+H  A +GH D+ + +L R+ + +N   ++GLS L++A Q++   +   L+   ++++++T++  +
Sbjct:  208 AAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYAD-VNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYT 347

HSP 2 Score: 52.7582 bits (125), Expect = 1.689e-7
Identity = 26/94 (27.66%), Postives = 52/94 (55.32%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLL 1142
            +   ++G TP+++A   G  ++  +L++ GA L V    G  P+H  +  G +++ + +LQRF    +   +NGL+ L++A   +N ++   LL
Sbjct:  141 DAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASP-DAAGKNGLTPLHVASHYDNQKVALLLL 233

HSP 3 Score: 52.373 bits (124), Expect = 2.342e-7
Identity = 28/84 (33.33%), Postives = 45/84 (53.57%), Query Frame = 3 
Query:  858 LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQ 1109
            +N     G TP+ +AC  G ++MV  L+  GAD+N    +G  P+H  A +GH  I+  +L +   + N    NG + L IA++
Sbjct:  338 VNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLL-KCGARPNDVTVNGNTALAIARR 420

HSP 4 Score: 51.6026 bits (122), Expect = 3.789e-7
Identity = 28/87 (32.18%), Postives = 49/87 (56.32%), Query Frame = 3 
Query:  882 KTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLL 1142
            +TP+++A  LGKLE+V+LL+   A  + A ++G  P+H  A +GH D+ T IL      +    + G + L++A +     + + LL
Sbjct:  115 QTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDV-TAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLL 200

HSP 5 Score: 48.521 bits (114), Expect = 3.244e-6
Identity = 30/109 (27.52%), Postives = 58/109 (53.21%), Query Frame = 3 
Query:  861 NVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLL--ASNIDSSTRISQS 1181
            NV+  +G TP+++AC   ++ +++LL+ +GA +     SG  P+H  A  G+++I+  +LQ      N  N  G + L++A +     +   LL   + +D+  R  Q+
Sbjct:    9 NVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASP-NATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQT 116
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002048.1 (pep scaffold:Pmarinus_7.0:GL477431:30859:73495:1 gene:ENSPMAG00000001850.1 transcript:ENSPMAT00000002048.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.8398 bits (133), Expect = 2.137e-8
Identity = 32/114 (28.07%), Postives = 61/114 (53.51%), Query Frame = 3 
Query:  858 LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLE 1199
            +N Q+++G T +  AC  G +++V++L++ GA+L   + SG+ P+   A+ GHV++   +L+R        N+   S L +A  K +  +  FLL +  D   +  +  T  +E
Sbjct:  193 VNAQSSTGNTALTYACAGGYVDVVRVLLEAGANLEDHNESGHTPLMEAASGGHVEVARLLLERGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALME 306

HSP 2 Score: 53.1434 bits (126), Expect = 1.513e-7
Identity = 27/68 (39.71%), Postives = 44/68 (64.71%), Query Frame = 3 
Query:  858 LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQ---RFP 1052
            ++V+N  G TP+ LA   G L++V+LLV+ GAD++ ADN    P+     KGHV ++ Y+++   +FP
Sbjct: 1196 IDVRNKKGNTPLWLAANGGHLDVVQLLVNSGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQFP 1263
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010100.1 (pep scaffold:Pmarinus_7.0:GL477764:15685:34523:-1 gene:ENSPMAG00000009140.1 transcript:ENSPMAT00000010100.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.9138 bits (128), Expect = 3.792e-8
Identity = 37/129 (28.68%), Postives = 62/129 (48.06%), Query Frame = 3 
Query:  771 AVSENSIL--YFTAI-ADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEM-VKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            AV+E   L  +++A+  D D          DT+N +   G TPV LAC    L +  +L+  +GAD+ +    G  P+H  A  GH  +L ++ +     +N  + +G+S L+ A    +     +LLA
Sbjct:  133 AVTEARALPIHYSAVRGDPDSTNALLQAAPDTVNARTREGVTPVYLACQERHLFLSFRLVEKWGADVTIQSEDGMTPLHAAAQNGHTPLLAWLTEFTVLNLNHVDGDGVSPLHFAAGGGHCSTMDWLLA 261
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Yeast
Match: HOS4 (Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate [Source:SGD;Acc:S000001374])

HSP 1 Score: 51.6026 bits (122), Expect = 2.340e-7
Identity = 22/64 (34.38%), Postives = 44/64 (68.75%), Query Frame = 3 
Query:  858 LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVA--DNSGNYPIHNCANKGHVDILTYILQ 1043
            +N Q+N+G T ++ A   G +E+V+LL++ GAD+N+   +  G+ P+ + +  GH+D++ Y+L+
Sbjct:  357 INDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLK 420

HSP 2 Score: 50.8322 bits (120), Expect = 4.233e-7
Identity = 20/60 (33.33%), Postives = 41/60 (68.33%), Query Frame = 3 
Query:  867 QNNSGKTPVNLACCLGKLEMVKLLVDFGA-DLNVADNSGNYPIHNCANKGHVDILTYILQ 1043
            +++ G+T + +AC  GK ++VK +++ G  D+N  DN+GN  +H  A +GH++I+  +++
Sbjct:  326 RDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIE 385
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO34161 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQ63])

HSP 1 Score: 65.0846 bits (157), Expect = 3.848e-13
Identity = 28/58 (48.28%), Postives = 42/58 (72.41%), Query Frame = 3 
Query:  867 QNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYIL 1040
            ++N+G TP++ AC  GKLE+VK+LV +GAD+N   N G  P+H+ A  GHV++L  +L
Sbjct:   16 KDNAGWTPLHEACARGKLEVVKVLVQYGADVNAHSNDGIRPLHDAAEGGHVEVLRLLL 73
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO34162 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQ64])

HSP 1 Score: 63.5438 bits (153), Expect = 1.537e-12
Identity = 27/58 (46.55%), Postives = 41/58 (70.69%), Query Frame = 3 
Query:  867 QNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYIL 1040
            ++N+G TP++ AC  GKLE+VK+L  +GAD+N   N G  P+H+ A  GHV++L  +L
Sbjct:   16 KDNAGWTPLHEACARGKLEVVKVLAQYGADVNAHSNDGIRPLHDAAEGGHVEVLRLLL 73
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO43690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXV8])

HSP 1 Score: 62.7734 bits (151), Expect = 6.903e-11
Identity = 42/135 (31.11%), Postives = 78/135 (57.78%), Query Frame = 3 
Query:  735 PVDKENLPKKEPAVSENS-ILYFTAIADNDEDKLFQVIDKDT-LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLET 1133
            PVD+    +K+P +  NS I++ +A++  D D++ +++ K   +N QN  G T ++ AC     ++VK+LVD GA ++V DN G   +H  A+ G V+I  Y+++   + +   N  G   L++A++++   L T
Sbjct:   35 PVDR---SRKKPKIQFNSGIVFLSAVSSGDVDEVKKLLAKGADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGAD-VAAVNNEGELPLDLAEEEDMEDLLT 165
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO42168 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S234])

HSP 1 Score: 55.4546 bits (132), Expect = 5.409e-10
Identity = 26/59 (44.07%), Postives = 35/59 (59.32%), Query Frame = 3 
Query:  858 LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTY 1034
            +N  N  G+TP++ AC    L  V +LV+ GAD NV DN G   +H  A  GH+D+L Y
Sbjct:   27 VNKVNGFGETPLHYACQAASLRFVNVLVENGADFNVLDNGGRSFLHIAAEHGHIDLLEY 85
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO34688 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNN7])

HSP 1 Score: 54.299 bits (129), Expect = 2.082e-9
Identity = 27/90 (30.00%), Postives = 53/90 (58.89%), Query Frame = 3 
Query:  870 NNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFL 1139
            +++G +PV+ A   G LE +KLL++ G D+N  D +G+ P+H  +  GH+  + Y+++   +    K++ G + LN+AK     ++  +L
Sbjct:    3 DDTGSSPVHKAAANGHLEALKLLLEHGGDINQCDITGSSPLHVSSRNGHLTCVKYLIENGADH-KLKSKKGNTALNVAKSSAQQKVAEYL 91
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:101158637])

HSP 1 Score: 66.6254 bits (161), Expect = 3.718e-11
Identity = 79/377 (20.95%), Postives = 141/377 (37.40%), Query Frame = 3 
Query:  210 GGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFESMHFVNN---------EEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQ------EKQQ---------------------------------YCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            GGW + M E +    TV  +D D  I V   S  +W FN A L         E +   E   +QF     V            ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q      E Q+                                  C G++ M+     G +  +K      V +E E KD D                           ++  A  D  E  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   D+L+ +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  270 GGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANVVRSGEVAAGAEGGSSQFHVGDLVQICYDIDRIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVTKIAPSGSAVSNASGERLSQLLKKLFETQESGDINEELVKAAANGDLAKVEDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLLKHNVDLEAEDKDGD-------------------------RAVHHAAFGD--EGSVIEVLQRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 618
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: mib1 (mindbomb E3 ubiquitin protein ligase 1 [Source:NCBI gene;Acc:101158637])

HSP 1 Score: 65.4698 bits (158), Expect = 8.225e-11
Identity = 76/353 (21.53%), Postives = 145/353 (41.08%), Query Frame = 3 
Query:  210 GGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAAL---------ESSDSKENDETQFESMHFVNN---------EEKPDVKISDELSQLTERLAAIEQVKPDTQNKAD------KKTPPSMVKTFKVGDMLRVSSNEKLIQ------EKQQYCGGYSKMRMRDLIGKIVTVKH--------YSVKCV-KVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT--LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLA 1145
            GGW + M E +    TV  +D D  I V   S  +W FN A L         E +   E   +QF     V            ++   + ++ +     ++  ++Q+  D+  K +         P ++ K    G  +  +S E+L Q      E Q+      ++      G +  V+          + +C      +    + H D+L   + K N+  +      +  ++  A  D  E  + +V+ +    LN +N   +TP+++A   G L++VK L+DFG   ++ D+ G+ P+H+  +K   D+L+ +L+   + +   N NG + L+ A  + N      LL+
Sbjct:  270 GGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANVVRSGEVAAGAEGGSSQFHVGDLVQICYDIDRIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVTKIAPSGSAVSNASGERLSQLLKKLFETQESGDINEELVKAAANGDLAKVEDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLL-KHNVDLEAEDKDGDRAVHHAAFGD--EGSVIEVLQRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGAD-VTITNNNGFNALHHAALRGNPSAMRVLLS 618
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000038944.1 (tankyrase-1 [Source:NCBI gene;Acc:101158122])

HSP 1 Score: 63.5438 bits (153), Expect = 4.439e-10
Identity = 37/114 (32.46%), Postives = 62/114 (54.39%), Query Frame = 3 
Query:  852 DTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVT 1187
            D +N ++  G+  TP++LA     LE+ + L++ GAD+N  D  G  P+HN A+ GHVDI   +L ++   +N  ++   + L+ A QK   +L   LLA   D + +  +  T
Sbjct:  773 DNINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA-LLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQT 885

HSP 2 Score: 55.4546 bits (132), Expect = 1.161e-7
Identity = 39/125 (31.20%), Postives = 67/125 (53.60%), Query Frame = 3 
Query:  738 VDKENLPKKEPAVSENSILYFTAIADNDE--DKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAK 1106
            VD  N+  K+ A  +++ L+F A     +  D L Q+     ++ +++ G  P++ AC  G  E+V LL+  GA+ N  DN    P+H  A KG +D+   +LQ   +  N +N +G S L++A+
Sbjct:  149 VDAMNVNAKDMAGRKSTPLHFAAGFGRKDVVDHLLQM--GANVHARDDGGLIPLHNACSFGHSEVVSLLLCQGAEPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP-NIRNTDGKSALDLAE 270

HSP 3 Score: 53.1434 bits (126), Expect = 6.867e-7
Identity = 33/122 (27.05%), Postives = 62/122 (50.82%), Query Frame = 3 
Query:  798 FTAIADNDEDKLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNID 1157
              A    +E+KL  ++    +N   + G+  TP++LA    ++ +V+LL+  GAD++  D  G  P+HN  + GH ++ T +L +    +N  +    + L+ A  KN   + + LL+   D
Sbjct:  287 LEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEV-TELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGAD 407
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: tnksb (tankyrase-1-like [Source:NCBI gene;Acc:105353570])

HSP 1 Score: 62.3882 bits (150), Expect = 9.849e-10
Identity = 35/116 (30.17%), Postives = 65/116 (56.03%), Query Frame = 3 
Query:  828 KLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTR 1169
            ++ ++  ++ +N ++  G+  TP++LA     LE+ + L++ GAD+N  D  G  P+HN A+ GHVDI   +L ++   +N  ++   + L+ A QK   +L   LLA   D + +
Sbjct:  748 RVQKLCSQENINCRDAQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA-LLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMK 862

HSP 2 Score: 54.6842 bits (130), Expect = 1.987e-7
Identity = 39/124 (31.45%), Postives = 65/124 (52.42%), Query Frame = 3 
Query:  738 VDKENLPKKEPAVSENSILYFTAIADNDE--DKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIA 1103
            VD  N+  K+ A  +++ L+F A     +  + L Q      ++ +++ G  P++ AC  G  E+V LL+  GAD N  DN    P+H  A KG +D+   +LQ   +  N +N +G S L++A
Sbjct:  132 VDTVNVNAKDMAGRKSTPLHFAAGFGRKDVVEHLLQT--GANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHESAIKGKIDVCIVLLQHGADP-NIRNTDGKSALDLA 252

HSP 3 Score: 53.9138 bits (128), Expect = 3.385e-7
Identity = 33/122 (27.05%), Postives = 62/122 (50.82%), Query Frame = 3 
Query:  798 FTAIADNDEDKLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNID 1157
              A    +E+KL  ++    +N   + G+  TP++LA    ++ +V+LL+  GAD++  D  G  P+HN  + GH ++ T +L +    +N  +    + L+ A  KN   + + LL+   D
Sbjct:  270 LEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEV-TELLLKHGACVNAMDLWQFTPLHEAASKNRMEVCSLLLSHGAD 390
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Match: tnksb (tankyrase-1-like [Source:NCBI gene;Acc:105353570])

HSP 1 Score: 62.3882 bits (150), Expect = 1.030e-9
Identity = 35/116 (30.17%), Postives = 65/116 (56.03%), Query Frame = 3 
Query:  828 KLFQVIDKDTLNVQNNSGK--TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTR 1169
            ++ ++  ++ +N ++  G+  TP++LA     LE+ + L++ GAD+N  D  G  P+HN A+ GHVDI   +L ++   +N  ++   + L+ A QK   +L   LLA   D + +
Sbjct:  755 RVQKLCSQENINCRDAQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA-LLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMK 869

HSP 2 Score: 54.6842 bits (130), Expect = 1.939e-7
Identity = 39/124 (31.45%), Postives = 65/124 (52.42%), Query Frame = 3 
Query:  738 VDKENLPKKEPAVSENSILYFTAIADNDE--DKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIA 1103
            VD  N+  K+ A  +++ L+F A     +  + L Q      ++ +++ G  P++ AC  G  E+V LL+  GAD N  DN    P+H  A KG +D+   +LQ   +  N +N +G S L++A
Sbjct:  132 VDTVNVNAKDMAGRKSTPLHFAAGFGRKDVVEHLLQT--GANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHESAIKGKIDVCIVLLQHGADP-NIRNTDGKSALDLA 252

HSP 3 Score: 51.6026 bits (122), Expect = 2.258e-6
Identity = 33/129 (25.58%), Postives = 62/129 (48.06%), Query Frame = 3 
Query:  798 FTAIADNDEDKLFQVIDKDTLNVQNNSGK---------TPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNID 1157
              A    +E+KL  ++    +N   + G+         TP++LA    ++ +V+LL+  GAD++  D  G  P+HN  + GH ++ T +L +    +N  +    + L+ A  KN   + + LL+   D
Sbjct:  270 LEAARSGNEEKLMALLTPLNVNCHASDGRKSTSQKMLSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEV-TELLLKHGACVNAMDLWQFTPLHEAASKNRMEVCSLLLSHGAD 397
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000020728.1 (SMESG000020728.1)

HSP 1 Score: 997.653 bits (2578), Expect = 0.000e+0
Identity = 496/500 (99.20%), Postives = 499/500 (99.80%), Query Frame = 3 
Query:   60 MGNYLQKDNSSNQFRMIKSLKDEPDSYFFNGKKVRVINNKAYVKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAALESSDSKENDETQFESMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKADKKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEISLFSPPTTITRTNEDENSEFPTRYPAITISSSLMDPPRDEFDTIEVPXXXXXXXXXXXXXXXYTMNSTPVKNECMICRDGHLNTAFVQCGHLACNVCADRIFRCHICQAEIEKKIFIYL 1559
            MGNYLQKDNSSNQFRMIKSLKDEPDSYFFNGKKVRVINNKAYVKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAALESSDSKENDETQFESMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKADKKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGK YDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEISLFSPPTTITRTN+DENSEFPTRYPAITISSSLMDPPRDEFDTIEVPSIPINSSSMANSSN+YTMNSTPV+NECMICRDGHLNTAFVQCGHLACNVCADRIFRCHICQAEIEKKIFIYL
Sbjct:    1 MGNYLQKDNSSNQFRMIKSLKDEPDSYFFNGKKVRVINNKAYVKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAALESSDSKENDETQFESMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKADKKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKYYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEISLFSPPTTITRTNDDENSEFPTRYPAITISSSLMDPPRDEFDTIEVPSIPINSSSMANSSNLYTMNSTPVENECMICRDGHLNTAFVQCGHLACNVCADRIFRCHICQAEIEKKIFIYL 500
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000020728.1 (SMESG000020728.1)

HSP 1 Score: 983.4 bits (2541), Expect = 0.000e+0
Identity = 491/500 (98.20%), Postives = 495/500 (99.00%), Query Frame = 3 
Query:   60 MGNYLQKDNSSNQFRMIKSLKDEPDSYFFNGKKVRVINNKAYVKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAALESSDSKENDETQFESMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKADKKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEISLFSPPTTITRTNEDENSEFPTRYPAITISSSLMDPPRDEFDTIEVPXXXXXXXXXXXXXXXYTMNSTPVKNECMICRDGHLNTAFVQCGHLACNVCADRIFRCHICQAEIEKKIFIYL 1559
            MGNYLQKDNSSNQFRMIKSLKDEPDSYFFNGKKVRVINNKAYVKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAALESSDSKENDETQFESMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKADKKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGK YDLHPDILDYPVDKENLPK    +SENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEISLFSPPTTITRTN+DENSEFPTRYPAITISSSLMDPPRDEFDTIEVPSIPINSSSMANSSN+YTMNSTPV+NECMICRDGHLNTAFVQCGHLACNVCADRIFRCHICQAEIEKKIFIYL
Sbjct:    1 MGNYLQKDNSSNQFRMIKSLKDEPDSYFFNGKKVRVINNKAYVKYIQSSCGGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAALESSDSKENDETQFESMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKADKKTPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKYYDLHPDILDYPVDKENLPK----ISENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLASNIDSSTRISQSVTNSLEISLFSPPTTITRTNDDENSEFPTRYPAITISSSLMDPPRDEFDTIEVPSIPINSSSMANSSNLYTMNSTPVENECMICRDGHLNTAFVQCGHLACNVCADRIFRCHICQAEIEKKIFIYL 496
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000045407.1 (SMESG000045407.1)

HSP 1 Score: 142.124 bits (357), Expect = 7.178e-38
Identity = 98/343 (28.57%), Postives = 170/343 (49.56%), Query Frame = 3 
Query:  528 KTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVKHYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLAS--NIDSSTRISQSVTNSLEISLFSPPTTITRTNEDENSEFPTRYPAITISSS------LMDPPRDEFDTIEVPXXXXXXXXXXXXXXXYTMNSTPVKNE--CMICRDGHLNTAFVQCGHLACNVCADRIFRCHICQ 1526
            + F  G+ L+V S++      Q  C GYS +RM  L G  VTV+H+S   V V+K+  +Y LHP+ L+                      F A+   +E+KL +++  + +NVQN  G+TP++LAC LG + +VKLL+ F  +  + DN G+ PIH   +  H DI+ Y+ +  P+ +  KN  G S+ +IA+ KN+ +L   +L +   I   ++  Q +       L   P    + +E+E+ E P+    +++ S       + +P   E +++E  ++   S          + N   +  E  C IC+D  + T  ++CGH+ C  C+ R+  C +C+
Sbjct:    6 RHFVNGEKLKVISDKDKFINLQDKCRGYSSIRMNHLPGSYVTVEHFSPTEVLVKKDNLEYYLHPETLEIYTS-----------------LFDAVTKGEEEKLRKLLHGENVNVQNEFGQTPIHLACYLGHINIVKLLLKFNPNFYIPDNKGDLPIHTTVDLKHYDIINYLRENVPDILEAKNSKGQSVQDIAENKNDEQLNNIILINLQTIPFPSKQCQPI-------LVREP----QNSENESME-PSTLRTLSMPSKECQMILVREPQNSENESMEPSTLQTISMPSKQYQMEASENHEYIPEELTCAICKD-RMKTTILECGHMFCRECSRRLPLCPMCR 318
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000045407.1 (SMESG000045407.1)

HSP 1 Score: 108.997 bits (271), Expect = 2.096e-26
Identity = 71/253 (28.06%), Postives = 130/253 (51.38%), Query Frame = 3 
Query:  798 FTAIADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNNHRLETFLLAS--NIDSSTRISQSVTNSLEISLFSPPTTITRTNEDENSEFPTRYPAITISSS------LMDPPRDEFDTIEVPXXXXXXXXXXXXXXXYTMNSTPVKNE--CMICRDGHLNTAFVQCGHLACNVCADRIFRCHICQ 1526
            F A+   +E+KL +++  + +NVQN  G+TP++LAC LG + +VKLL+ F  +  + DN G+ PIH   +  H DI+ Y+ +  P+ +  KN  G S+ +IA+ KN+ +L   +L +   I   ++  Q +       L   P    + +E+E+ E P+    +++ S       + +P   E +++E  ++   S          + N   +  E  C IC+D  + T  ++CGH+ C  C+ R+  C +C+
Sbjct:   29 FDAVTKGEEEKLRKLLHGENVNVQNEFGQTPIHLACYLGHINIVKLLLKFNPNFYIPDNKGDLPIHTTVDLKHYDIINYLRENVPDILEAKNSKGQSVQDIAENKNDEQLNNIILINLQTIPFPSKQCQPI-------LVREP----QNSENESME-PSTLRTLSMPSKECQMILVREPQNSENESMEPSTLQTISMPSKQYQMEASENHEYIPEELTCAICKD-RMKTTILECGHMFCRECSRRLPLCPMCR 268
[Close]
BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000043462.1 (SMESG000043462.1)

HSP 1 Score: 80.8777 bits (198), Expect = 2.656e-16
Identity = 82/291 (28.18%), Postives = 131/291 (45.02%), Query Frame = 3 
Query:  714 HPDILDYPVDKENLPKKEPAVSENSILYFTAIADNDEDKLFQVIDKDT-LNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADLNVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQKNN-------HRLETFLLASNIDSSTRISQSVTNSLEISL-FSPPTTITRTNEDENSEFPTRYPAITISSSLMDPPRDEFDTIEVPXXXXXXXXXXXXXXXYTMNSTPVKNECMICRDGHLNTAFVQCGHLACNVCADRIFRCHICQAEIEKKIFIYL 1559
            H +IL   +D+    + E       I Y +    ++  KL  ++D++  +  Q+  G  P++ AC  G  E++KLL+D   ++   + SG   +H  ++ GH +IL  +LQR   + + K ++G S L++AKQ NN         +E F      D    I      +L IS  F  P   T  N     E      A  I   ++D   D    IE         S   +      N  P+   C IC+D  ++  F QCGHL CNVC+D++F C  C+A+I  +I ++ 
Sbjct:   81 HLEILKLLLDRNCNIECENRWGRIPIHYASGNGHSEILKL--LLDRNCNIECQDKWGNRPIHWACRNGHSEILKLLLDRNCNIECENKSGRRSVHFASSNGHSEILKLLLQR-KCRFDCKTKDGKSPLDLAKQFNNVDCVELLTHVEKFFAIIARDDPIEIE-----NLFISFNFIQPNIYTGLNV---LEMAINNNAEKIVKCILDKSVDNKAEIERSHRNNAKLSKEENQPD---NEIPM---CHICQDNPVSIGF-QCGHLTCNVCSDQLFECPYCKADIVSRIKMFF 353
The following BLAST results are available for this feature:
BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MIB13.251e-1322.19mindbomb E3 ubiquitin protein ligase 1 [Source:HGN... [more]
CDKN2D8.295e-1235.29cyclin dependent kinase inhibitor 2D [Source:HGNC ... [more]
CDKN2D8.295e-1235.29cyclin dependent kinase inhibitor 2D [Source:HGNC ... [more]
ANKRD632.438e-1031.87ankyrin repeat domain 63 [Source:HGNC Symbol;Acc:H... [more]
PSMD104.308e-1031.68proteasome 26S subunit, non-ATPase 10 [Source:HGNC... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-443.461e-929.57AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-443.461e-929.57AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-443.596e-929.57AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-443.596e-929.57AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
unc-444.013e-929.57AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86][more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG425344.704e-1237.04gene:FBgn0260487 transcript:FBtr0300898[more]
CG425345.396e-1237.04gene:FBgn0260487 transcript:FBtr0309307[more]
Mbs1.982e-935.29gene:FBgn0005536 transcript:FBtr0301473[more]
Mbs2.072e-935.29gene:FBgn0005536 transcript:FBtr0301472[more]
Mbs2.144e-935.29gene:FBgn0005536 transcript:FBtr0308215[more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mib17.639e-1324.35mindbomb E3 ubiquitin protein ligase 1 [Source:NCB... [more]
mib14.699e-1221.56mindbomb E3 ubiquitin protein ligase 1 [Source:NCB... [more]
mib15.603e-1221.56mindbomb E3 ubiquitin protein ligase 1 [Source:NCB... [more]
bcl31.252e-1029.93BCL3 transcription coactivator [Source:ZFIN;Acc:ZD... [more]
cdkn2d3.372e-1045.76cyclin-dependent kinase inhibitor 2D (p19, inhibit... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mib14.519e-1224.35mindbomb E3 ubiquitin protein ligase 1 [Source:NCB... [more]
mib13.476e-1124.06mindbomb E3 ubiquitin protein ligase 1 [Source:NCB... [more]
PPP1R12A2.681e-1027.14protein phosphatase 1 regulatory subunit 12A [Sour... [more]
cpsf14.051e-1031.43cleavage and polyadenylation specific factor 1 [So... [more]
PPP1R12A4.236e-1027.14protein phosphatase 1 regulatory subunit 12A [Sour... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mib12.471e-1222.13mindbomb E3 ubiquitin protein ligase 1 [Source:MGI... [more]
Mib12.471e-1222.13mindbomb E3 ubiquitin protein ligase 1 [Source:MGI... [more]
Cdkn2d5.695e-1235.11cyclin dependent kinase inhibitor 2D [Source:MGI S... [more]
Cdkn2d5.884e-1235.11cyclin dependent kinase inhibitor 2D [Source:MGI S... [more]
Ankrd636.932e-1030.77ankyrin repeat domain 63 [Source:MGI Symbol;Acc:MG... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q86YT6|MIB1_HUMAN1.561e-1222.19E3 ubiquitin-protein ligase MIB1 OS=Homo sapiens O... [more]
sp|Q80SY4|MIB1_MOUSE1.728e-1122.13E3 ubiquitin-protein ligase MIB1 OS=Mus musculus O... [more]
sp|Q804S5|MIB1_DANRE3.547e-1121.56E3 ubiquitin-protein ligase mib1 OS=Danio rerio OX... [more]
sp|Q60773|CDN2D_MOUSE3.984e-1135.11Cyclin-dependent kinase 4 inhibitor D OS=Mus muscu... [more]
sp|P55273|CDN2D_HUMAN3.984e-1135.29Cyclin-dependent kinase 4 inhibitor D OS=Homo sapi... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Z2HRF35.311e-1424.22E3 ubiquitin-protein ligase mib1 OS=Liparis tanaka... [more]
A0A3R7N7Q12.277e-1238.71Death-associated protein kinase 1 OS=Penaeus vanna... [more]
S9WGW34.144e-1225.29E3 ubiquitin-protein ligase MIB1 OS=Camelus ferus ... [more]
A0A3L7I1W54.903e-1222.29MIB1 OS=Cricetulus griseus OX=10029 GN=CgPICR_0152... [more]
A0A5B7EPJ41.585e-1131.58Death-associated protein kinase 1 OS=Portunus trit... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mib18.906e-1121.53mindbomb E3 ubiquitin protein ligase 1 [Source:NCB... [more]
mib19.281e-1121.53mindbomb E3 ubiquitin protein ligase 1 [Source:NCB... [more]
tnksb1.194e-1033.33tankyrase-1 [Source:NCBI gene;Acc:103045612][more]
tnksb1.249e-1033.33tankyrase-1 [Source:NCBI gene;Acc:103045612][more]
nfkbie1.520e-1032.59NFKB inhibitor epsilon [Source:NCBI gene;Acc:10302... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000009608.16.229e-1131.03pep scaffold:Pmarinus_7.0:GL477242:23155:61557:-1 ... [more]
ENSPMAT00000007446.17.782e-1024.46pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1... [more]
ENSPMAT00000007449.11.008e-924.11pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1... [more]
ENSPMAT00000002048.12.137e-828.07pep scaffold:Pmarinus_7.0:GL477431:30859:73495:1 g... [more]
ENSPMAT00000010100.13.792e-828.68pep scaffold:Pmarinus_7.0:GL477764:15685:34523:-1 ... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
HOS42.340e-734.38Subunit of the Set3 complex; complex is a meiotic-... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO341613.848e-1348.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO341621.537e-1246.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO436906.903e-1131.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO421685.409e-1044.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO346882.082e-930.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mib13.718e-1120.95mindbomb E3 ubiquitin protein ligase 1 [Source:NCB... [more]
mib18.225e-1121.53mindbomb E3 ubiquitin protein ligase 1 [Source:NCB... [more]
ENSORLT00000038944.14.439e-1032.46tankyrase-1 [Source:NCBI gene;Acc:101158122][more]
tnksb9.849e-1030.17tankyrase-1-like [Source:NCBI gene;Acc:105353570][more]
tnksb1.030e-930.17tankyrase-1-like [Source:NCBI gene;Acc:105353570][more]
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BLAST of ANK_REP_REGION domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000020728.10.000e+099.20SMESG000020728.1[more]
SMESG000020728.10.000e+098.20SMESG000020728.1[more]
SMESG000045407.17.178e-3828.57SMESG000045407.1[more]
SMESG000045407.12.096e-2628.06SMESG000045407.1[more]
SMESG000043462.12.656e-1628.18SMESG000043462.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023269 ID=SMED30023269|Name=ANK_REP_REGION domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1576bp
ATTTTCTACAGTTCAAAGGTTAAATCTAGAATAATCAATAATATATTATT
ATTATTAAAATGGGAAATTACTTGCAAAAAGATAATTCATCAAATCAATT
CAGAATGATAAAAAGTTTAAAAGATGAACCAGATAGTTATTTTTTTAATG
GGAAAAAGGTTCGAGTTATTAACAATAAGGCATACGTTAAATACATTCAG
TCTTCATGTGGTGGCTGGGATGAAAGTATGACTGAATGTATCAATCAAAT
ATGTACAGTGTTAAATGTTGACCATGACAAAGCCATAAATGTCATTACCG
CATCCAAACAGAAATGGTTATTTAATAGAGCAGCCTTAGAGTCATCGGAT
TCGAAGGAAAATGATGAAACTCAATTTGAATCTATGCATTTTGTAAATAA
TGAAGAAAAACCAGACGTGAAAATTTCAGATGAATTGTCACAACTAACGG
AAAGACTAGCTGCGATTGAACAAGTGAAACCGGACACACAAAATAAAGCA
GACAAAAAAACGCCACCATCAATGGTTAAAACATTCAAAGTTGGAGATAT
GTTACGAGTGTCTTCGAATGAAAAGTTAATTCAAGAAAAGCAACAATATT
GTGGTGGGTACTCAAAAATGCGAATGCGTGACCTCATTGGGAAAATTGTT
ACTGTCAAACATTACAGTGTAAAATGTGTCAAAGTTGAAAAAGAGGGAAA
AGATTATGATTTGCATCCTGATATTTTAGATTATCCAGTAGATAAAGAAA
ATTTGCCAAAAAAAGAACCAGCCGTTTCAGAAAACAGTATTCTTTATTTT
ACTGCTATAGCGGACAACGATGAGGATAAGCTTTTCCAAGTAATTGACAA
AGACACGTTAAATGTGCAAAATAATTCTGGTAAAACTCCAGTAAATTTAG
CATGCTGTCTTGGGAAACTTGAAATGGTGAAATTGCTCGTTGATTTCGGT
GCAGATTTAAATGTGGCGGATAACAGTGGGAATTACCCAATTCATAATTG
TGCAAATAAAGGACATGTCGATATTTTGACTTATATTCTACAGAGGTTCC
CAGAACAAATTAACAAGAAAAATCAAAATGGATTATCATTGCTTAACATC
GCAAAACAAAAGAACAATCATAGATTAGAAACATTTCTCCTAGCCAGCAA
TATAGATTCTTCAACTAGAATTTCTCAATCTGTTACTAACAGTCTTGAGA
TTTCTTTGTTTTCTCCTCCAACAACAATTACACGTACAAATGAAGACGAA
AATTCAGAATTCCCCACCAGATATCCAGCTATTACAATTTCTTCTTCATT
AATGGATCCTCCAAGAGATGAATTTGACACAATCGAAGTGCCTTCTATTC
CAATTAATAGTTCAAGTATGGCGAATTCTTCAAATATCTACACTATGAAT
TCGACCCCGGTTAAAAATGAATGTATGATTTGCCGAGACGGACATTTAAA
CACAGCTTTTGTCCAATGTGGACATTTAGCTTGCAACGTCTGTGCTGACA
GAATATTTCGGTGCCATATCTGTCAAGCTGAAATTGAAAAAAAAATATTT
ATATATTTATAATAACAGTATTGGAT
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protein sequence of SMED30023269-orf-1

>SMED30023269-orf-1 ID=SMED30023269-orf-1|Name=SMED30023269-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=501bp
MGNYLQKDNSSNQFRMIKSLKDEPDSYFFNGKKVRVINNKAYVKYIQSSC
GGWDESMTECINQICTVLNVDHDKAINVITASKQKWLFNRAALESSDSKE
NDETQFESMHFVNNEEKPDVKISDELSQLTERLAAIEQVKPDTQNKADKK
TPPSMVKTFKVGDMLRVSSNEKLIQEKQQYCGGYSKMRMRDLIGKIVTVK
HYSVKCVKVEKEGKDYDLHPDILDYPVDKENLPKKEPAVSENSILYFTAI
ADNDEDKLFQVIDKDTLNVQNNSGKTPVNLACCLGKLEMVKLLVDFGADL
NVADNSGNYPIHNCANKGHVDILTYILQRFPEQINKKNQNGLSLLNIAKQ
KNNHRLETFLLASNIDSSTRISQSVTNSLEISLFSPPTTITRTNEDENSE
FPTRYPAITISSSLMDPPRDEFDTIEVPSIPINSSSMANSSNIYTMNSTP
VKNECMICRDGHLNTAFVQCGHLACNVCADRIFRCHICQAEIEKKIFIYL
*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036770Ankyrin_rpt-contain_sf
IPR040847SH3_15
IPR002110Ankyrin_rpt
IPR013083Znf_RING/FYVE/PHD
IPR020683Ankyrin_rpt-contain_dom
IPR001841Znf_RING
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0008270zinc ion binding
GO:0004842ubiquitin-protein transferase activity
GO:0016874ligase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0016567protein ubiquitination
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002110Ankyrin repeatSMARTSM00248ANK_2acoord: 306..336
e-value: 1.3
score: 18.0
coord: 273..302
e-value: 2.6E-4
score: 30.4
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 273..305
score: 13.651
NoneNo IPR availablePFAMPF13637Ank_4coord: 285..327
e-value: 5.0E-8
score: 33.3
NoneNo IPR availablePFAMPF13920zf-C3HC4_3coord: 452..494
e-value: 4.3E-9
score: 36.1
NoneNo IPR availablePANTHERPTHR24127FAMILY NOT NAMEDcoord: 251..361
coord: 144..327
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 449..495
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 433..500
e-value: 1.5E-12
score: 48.7
IPR036770Ankyrin repeat-containing domain superfamilyGENE3DG3DSA:1.25.40.20coord: 212..378
e-value: 8.2E-24
score: 86.1
IPR036770Ankyrin repeat-containing domain superfamilySUPERFAMILYSSF48403Ankyrin repeatcoord: 244..370
IPR040847Mind bomb, SH3 repeat domainPFAMPF18346SH3_15coord: 31..93
e-value: 1.9E-8
score: 34.5
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 455..489
score: 9.421
IPR020683Ankyrin repeat-containing domainPROSITEPS50297ANK_REP_REGIONcoord: 267..372
score: 23.843