Acyl-CoA dehydrogenase very long chain

Query:  122 SCVRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIK------------SVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDLNLVDIHYNE---TIKSIAEHLVQSEGVVQQNPLGF 1846
            +  R+    + SKSFA+ +F G++   Q+FP+P VL++EQ + L++++ P+ +FFEEVN+PAKND LE +E  + Q LK+LGAFGLQVP E GG+GL NTQYARLVEIVG +D+GVGI LGAHQSIGFKGILL+GTK QK KYLP LASG+ +AA+CLTEPS+GSDA +I+  A  S  G +Y LNGSKLWISNGG+ +IFTVFAKT   D  T     KITAF+V+R FGGI+H PPEKKMGIK SNTA +FF+  ++P+ENVLG  G+GFKVAM+ILNNGRFGMAA L+GTMR  I KAV HA  R  F  KI  + ++QEKLA M + QY+TESMA+ +S NMD+   DFQ+EAAISK++ SEAAW   DE IQI+GGMG+MKE G+E+ +RD+RIFRIFEG+NDILRLF+  QG +  GK+     + L+N F   ++    G   KQL +             VHPEL  S +L    +  F       L KH+K I+N+Q +L+ LAD  + +Y + V LSRAS ++    P+A ++  L       A + +R  +  L   D    E     KSI++ LV+  GVV  NPLGF
Sbjct:   82 ALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFG--NAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQ-SDPWQQELYRNFKSISKALVERGGVVTSNPLGF 678          

Query:  122 SCVRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIK------------SVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDLNLVDIHYNE---TIKSIAEHLVQSEGVVQQNPLGF 1846
            +  R+    + SKSFA+ +F G++   Q+FP+P VL++EQ + L++++ P+ +FFEEVN+PAKND LE +E  + Q LK+LGAFGLQVP E GG+GL NTQYARLVEIVG +D+GVGI LGAHQSIGFKGILL+GTK QK KYLP LASG+ +AA+CLTEPS+GSDA +I+  A  S  G +Y LNGSKLWISNGG+ +IFTVFAKT   D  T     KITAF+V+R FGGI+H PPEKKMGIK SNTA +FF+  ++P+ENVLG  G+GFKVAM+ILNNGRFGMAA L+GTMR  I KAV HA  R  F  KI  + ++QEKLA M + QY+TESMA+ +S NMD+   DFQ+EAAISK++ SEAAW   DE IQI+GGMG+MKE G+E+ +RD+RIFRIFEG+NDILRLF+  QG +  GK+     + L+N F   ++    G   KQL +             VHPEL  S +L    +  F       L KH+K I+N+Q +L+ LAD  + +Y + V LSRAS ++    P+A ++  L       A + +R  +  L   D    E     KSI++ LV+  GVV  NPLGF
Sbjct:   59 ALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFG--NAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQ-SDPWQQELYRNFKSISKALVERGGVVTSNPLGF 655          

Query:  155 SKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIK------------SVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDLNLVDIHYNE---TIKSIAEHLVQSEGVVQQNPLGF 1846
            SKSFA+ +F G++   Q+FP+P VL++EQ + L++++ P+ +FFEEVN+PAKND LE +E  + Q LK+LGAFGLQVP E GG+GL NTQYARLVEIVG +D+GVGI LGAHQSIGFKGILL+GTK QK KYLP LASG+ +AA+CLTEPS+GSDA +I+  A  S  G +Y LNGSKLWISNGG+ +IFTVFAKT   D  T     KITAF+V+R FGGI+H PPEKKMGIK SNTA +FF+  ++P+ENVLG  G+GFKVAM+ILNNGRFGMAA L+GTMR  I KAV HA  R  F  KI  + ++QEKLA M + QY+TESMA+ +S NMD+   DFQ+EAAISK++ SEAAW   DE IQI+GGMG+MKE G+E+ +RD+RIFRIFEG+NDILRLF+  QG +  GK+     + L+N F   ++    G   KQL +             VHPEL  S +L    +  F       L KH+K I+N+Q +L+ LAD  + +Y + V LSRAS ++    P+A ++  L       A + +R  +  L   D    E     KSI++ LV+  GVV  NPLGF
Sbjct:   48 SKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFG--NAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQ-SDPWQQELYRNFKSISKALVERGGVVTSNPLGF 633          

Query:  158 KSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDS----KTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRK-VQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLG----------KKYKNNNLLQNVFSGLSSSF----TYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVK-----------FALSNVRRYVTDLNLVDIHYNETIKSIAEHLVQSEGVVQQNPL 1840
            ++FA  LF GK+   ++FPFP+V S+++   + Q + P+ KFF E  +  K D+   I  ++++ LK LG FGLQVPEEYGG+G +NT Y+RL EI+ + D  + + L AHQ+IG KGI+L GT+EQKAKYLP LASG+ IAA+CLTEP++GSDA +I+++A  S D  HYILNGSK+WI+NGG+  IFTVFAKT   DS    K KITAFIV+R+FGG+++  PE K+GI+ SNT  + FEN KIP EN+LG  G+GFKVAMNILN+GRF M + ++G ++  I+    +A  R  F  ++ E+ ++QEK A MA K Y+ ESM +  +G +D+    D  +EAA+ KV++SEAAW CV EA+QILGG+GY ++   E+ +RD RI  IFEG+N+ILR+++   G+ H G          K+ K + ++  V   L  S       G      +  VHP L +SA         FG     +L +  K I+ +QL+LK +A+ ++ +YG++  LSRAS ++     +  ++  L             F+LS + +Y  +      + +E IK +++ +++    +  +PL
Sbjct:   37 RAFAKELFLGKIKKKEVFPFPEV-SQDELNEINQFLGPVEKFFTEEVDSRKIDQEGKIPDETLEKLKSLGLFGLQVPEEYGGLGFSNTMYSRLGEII-SMDGSITVTLAAHQAIGLKGIILAGTEEQKAKYLPKLASGEHIAAFCLTEPASGSDAASIRSRATLSEDKKHYILNGSKVWITNGGLANIFTVFAKTEVVDSDGSVKDKITAFIVERDFGGVTNGKPEDKLGIRGSNTCEVHFENTKIPVENILGEVGDGFKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEYACTRKQFNKRLSEFGLIQEKFALMAQKAYVMESMTYLTAGMLDQPGFPDCSIEAAMVKVFSSEAAWQCVSEALQILGGLGYTRDYPYERILRDTRILLIFEGTNEILRMYIALTGLQHAGRILTTRIHELKQAKVSTVMDTVGRRLRDSLGRTVDLGLTGNHGV--VHPSLADSANKFEENTYCFGRTVETLLLRFGKTIMEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANTFCVEAYLQNLFSLSQLDKYAPE------NLDEQIKKVSQQILEKRAYICAHPL 617          

Query:  758 KTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRK-VQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLG----------KKYKNNNLLQNVFSGLSSSF----TYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVK-----------FALSNVRRYVTDLNLVDIHYNETIKSIAEHLVQSEGVVQQNPL 1840
            K KITAFIV+R+FGG+++  PE K+GI+ SNT  + FEN KIP EN+LG  G+GFKVAMNILN+GRF M + ++G ++  I+    +A  R  F  ++ E+ ++QEK A MA K Y+ ESM +  +G +D+    D  +EAA+ KV++SEAAW CV EA+QILGG+GY ++   E+ +RD RI  IFEG+N+ILR+++   G+ H G          K+ K + ++  V   L  S       G      +  VHP L +SA         FG     +L +  K I+ +QL+LK +A+ ++ +YG++  LSRAS ++     +  ++  L             F+LS + +Y  +      + +E IK +++ +++    +  +PL
Sbjct:    2 KDKITAFIVERDFGGVTNGKPEDKLGIRGSNTCEVHFENTKIPVENILGEVGDGFKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEYACTRKQFNKRLSEFGLIQEKFALMAQKAYVMESMTYLTAGMLDQPGFPDCSIEAAMVKVFSSEAAWQCVSEALQILGGLGYTRDYPYERILRDTRILLIFEGTNEILRMYIALTGLQHAGRILTTRIHELKQAKVSTVMDTVGRRLRDSLGRTVDLGLTGNHGV--VHPSLADSANKFEENTYCFGRTVETLLLRFGKTIMEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANTFCVEAYLQNLFSLSQLDKYAPE------NLDEQIKKVSQQILEKRAYICAHPL 380          

Query:  155 SKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKT---MGDDS-KTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLS-SSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDL--NLVDIHYNETIKSIAEHLVQSEGVVQQNPL 1840
            S SF ++LF GK    Q+FP+P  ++ EQ+E L  ++ P+ K   EVN+  KNDE   I    +    +LG FG+ VP E  G G NN+Q AR+ EIVG YD+G G+ +GAHQSIG+KGILL GT  QK KYLP LA+G+K AA+ LTEP+ GSDA +++ +A+ SADG HY+LNG K+WISNGG  ++FTVFA+T     D S K K++AFIV+R FGG++  P EKKMGIK SNT  + F+N KIP EN+LG EG GFKVAMNILNNGRFG+ A  +G M+ CI+K V H   RV F  K+ E+  +QEKL  M  K Y TES+ + +S NMDR ++++Q+EAAI KV ASE AW   D+AIQ+ GGMG+M+E GLE+ +RD+RIFRIFEG+ND+LRLF+   G  H GK             GL+ S  T G       + V   L++SAK+L  +I+LFG     +L KH+K II++Q  +  +AD  + IY  +  LSRA+ A++N   SA ++  +  +    A+ +  R++ D    + +     TI+S+A+ +  + G+  Q+P+
Sbjct:   39 SPSFVMNLFRGKAVTDQVFPYPLNMTDEQKETLGMVMSPLEKMLVEVNDVVKNDETSDIPRAVLDQFAELGTFGVLVPPELEGSGFNNSQMARVAEIVGAYDLGFGVVMGAHQSIGYKGILLEGTDAQKQKYLPDLATGRKFAAFALTEPTTGSDASSVRTRAELSADGKHYVLNGGKIWISNGGFADVFTVFAQTPVKQADGSTKDKMSAFIVERAFGGVTSGPQEKKMGIKGSNTTEVHFDNLKIPVENLLGKEGEGFKVAMNILNNGRFGIPAACTGAMKHCIQKTVDHITTRVQFGKKLQEFGNIQEKLVEMISKLYATESIVYMLSSNMDRGIKEYQLEAAIGKVLASENAWLVCDDAIQVHGGMGFMRETGLERVLRDLRIFRIFEGANDVLRLFIALTGAQHAGKHLAEQASGVGGLIGLAVSRVTGGNTGSNFGQVVDASLQDSAKVLDQQIALFGQTVQGLLMKHKKGIIDRQYEMHRVADAAINIYSSAAVLSRATYAIKNKSSSADFERKVATYYVDKAMKSSNRFLKDAGSGVENASKVATIESLAKEVCGNGGLTLQHPV 611          

Query:  155 SKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKT---MGDDS-KTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLS-SSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDL--NLVDIHYNETIKSIAEHLVQSEGVVQQNPL 1840
            S SF ++LF GK    Q+FP+P  ++ EQ+E L  ++ P+ K   EVN+  KNDE   I    +    +LG FG+ VP E  G G NN+Q AR+ EIVG YD+G G+ +GAHQSIG+KGILL GT  QK KYLP LA+G+K AA+ LTEP+ GSDA +++ +A+ SADG HY+LNG K+WISNGG  ++FTVFA+T     D S K K++AFIV+R FGG++  P EKKMGIK SNT  + F+N KIP EN+LG EG GFKVAMNILNNGRFG+ A  +G M+ CI+K V H   RV F  K+ E+  +QEKL  M  K Y TES+ + +S NMDR ++++Q+EAAI KV ASE AW   D+AIQ+ GGMG+M+E GLE+ +RD+RIFRIFEG+ND+LRLF+   G  H GK             GL+ S  T G       + V   L++SAK+L  +I+LFG     +L KH+K II++Q  +  +AD  + IY  +  LSRA+ A++N   SA ++  +  +    A+ +  R++ D    + +     TI+S+A+ +  + G+  Q+P+
Sbjct:   39 SPSFVMNLFRGKAVTDQVFPYPLNMTDEQKETLGMVMSPLEKMLVEVNDVVKNDETSDIPRAVLDQFAELGTFGVLVPPELEGSGFNNSQMARVAEIVGAYDLGFGVVMGAHQSIGYKGILLEGTDAQKQKYLPDLATGRKFAAFALTEPTTGSDASSVRTRAELSADGKHYVLNGGKIWISNGGFADVFTVFAQTPVKQADGSTKDKMSAFIVERAFGGVTSGPQEKKMGIKGSNTTEVHFDNLKIPVENLLGKEGEGFKVAMNILNNGRFGIPAACTGAMKHCIQKTVDHITTRVQFGKKLQEFGNIQEKLVEMISKLYATESIVYMLSSNMDRGIKEYQLEAAIGKVLASENAWLVCDDAIQVHGGMGFMRETGLERVLRDLRIFRIFEGANDVLRLFIALTGAQHAGKHLAEQASGVGGLIGLAVSRVTGGNTGSNFGQVVDASLQDSAKVLDQQIALFGQTVQGLLMKHKKGIIDRQYEMHRVADAAINIYSSAAVLSRATYAIKNKSSSADFERKVATYYVDKAMKSSNRFLKDAGSGVENASKVATIESLAKEVCGNGGLTLQHPV 611          

Query:  227 LSKEQEENLQQMIPPIVKFFEEV--NNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALG-AHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTK----ITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFL 1348
            +S +  E  +++    +KF ++V   N AK DE      + ++    LG    Q+PE+YGG G+   + A +VE + +Y    GI LG    S+    + + G +EQK KYL +LA+   IA+YC+TEP AGSD   ++ K +K  D   YI+NGSK WI+ GG  + F V A++   + KT      TAFIVD +  GI+    EK MG +CS+T  + FE+ ++PAENVLG  G GFKVAM   +  R G+AAG  G    C+ ++  +A+ER  F T I  +  VQ  LA MA+   +   + +  + ++D KV+     A+I+K +A++ A      A+QI GG G+  E  +EK MRD +I++I+EG++ I R+ +
Sbjct:   27 ISFDLSETQKEIQDAALKFSKDVLVPNAAKFDESGEFPWEIVRQAHSLGLMNPQIPEKYGGPGMTTLETALIVEAL-SYGC-TGIQLGIMGPSLAIAPVYISGNEEQKKKYLGALAAEPIIASYCVTEPGAGSDVNGVKTKCEKKGD--EYIINGSKAWITGGGHAKWFFVLARS-DPNPKTPAGKAFTAFIVDGDTPGITRGKKEKNMGQRCSDTRVITFEDVRVPAENVLGAPGAGFKVAMEAFDMTRPGVAAGALGLSWRCLDESAKYALERKAFGTVIANHQAVQFMLADMAVNLELARLITYKSANDVDNKVRS-SYNASIAKCFAADTANQAATNAVQIFGGNGFNSEYPVEKLMRDAKIYQIYEGTSQIQRIVI 401          

Query:  227 LSKEQEENLQQMIPPIVKFFEEV--NNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALG-AHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTK----ITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFL 1348
            +S +  E  +++    +KF ++V   N AK DE      + ++    LG    Q+PE+YGG G+   + A +VE + +Y    GI LG    S+    + + G +EQK KYL +LA+   IA+YC+TEP AGSD   ++ K +K  D   YI+NGSK WI+ GG  + F V A++   + KT      TAFIVD +  GI+    EK MG +CS+T  + FE+ ++PAENVLG  G GFKVAM   +  R G+AAG  G    C+ ++  +A+ER  F T I  +  VQ  LA MA+   +   + +  + ++D KV+     A+I+K +A++ A      A+QI GG G+  E  +EK MRD +I++I+EG++ I R+ +
Sbjct:   27 ISFDLSETQKEIQDAALKFSKDVLVPNAAKFDESGEFPWEIVRQAHSLGLMNPQIPEKYGGPGMTTLETALIVEAL-SYGC-TGIQLGIMGPSLAIAPVYISGNEEQKKKYLGALAAEPIIASYCVTEPGAGSDVNGVKTKCEKKGD--EYIINGSKAWITGGGHAKWFFVLARS-DPNPKTPAGKAFTAFIVDGDTPGITRGKKEKNMGQRCSDTRVITFEDVRVPAENVLGAPGAGFKVAMEAFDMTRPGVAAGALGLSWRCLDESAKYALERKAFGTVIANHQAVQFMLADMAVNLELARLITYKSANDVDNKVRS-SYNASIAKCFAADTANQAATNAVQIFGGNGFNSEYPVEKLMRDAKIYQIYEGTSQIQRIVI 401          

Query:  221 KVLSKEQEENLQQMIPPIVKFFEEV--NNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTK----ITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDR-KVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFL 1348
            + +S E  +  +++    +KF ++V   N AK D+      + ++    LG     +PE+YGG GL+N   A +VE +     G+ IA+    S+    I L GT+EQK KYL  LA+   IA+YC+TEP AGSD   ++ KA K  D   YI+NGSK WI+ GG  + F V A+T  D+ KT      TAFIVD +  GI+    E  MG +CS+T ++ FE+ ++P EN+LG  G GFKVAM   +  R  +AA   G    C+ ++  +AMER  F T I  +  VQ  +A MA+   ++    +  +  +D   V  +   A+I+K +A++ A      A QI GG G+  E  +EK MRD +I++I+EG++ I R+ +
Sbjct:   19 RQMSFELSDTQKEIQSHAIKFSKDVLVPNAAKFDKSGEFPWEIVKQAHSLGFMNTIIPEKYGGPGLSNLDTALIVEALSYGCSGLQIAIFG-PSLAAAPICLSGTEEQKKKYLGMLAAEPIIASYCVTEPGAGSDVNGVKTKAVKQGD--EYIINGSKAWITGGGHAKWFFVLART-DDNPKTPAGKAFTAFIVDGDTPGITRGKKENNMGQRCSDTRSITFEDVRVPKENILGAPGAGFKVAMGAFDLTRPQVAASAVGLAWRCLDESTKYAMERHAFGTPIANHQGVQFMIADMAINLELSRLFTYRAAAEVDSYGVSSYN--ASIAKCFAADTANVAATNACQIFGGAGFNCEYPVEKLMRDAKIYQIYEGTSQIQRMVI 395          

Query:  131 RRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLSSSF-------------TYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVK-FALSNVRRYVTDLNLVDIHY----NETIKSIAEHLVQSEGVV 1825
            R     S ++SF  ++F G +  +Q+FP+P VL+ EQ+E    +I P  +FF +VN+ A+ND    I+  +   L +LGAFG+QVP E+GG+GLNNTQY RL  IVG  D+G+GI +GAHQSIGFKGILLYGT EQK KYLP +A+ +  AA+ LTEPS+GSDA +I+ +A KSADG HY+LNGSK+WISNGGI EI TVFA+T   D KT     K+TAFIV+R FGG+++ PPEKKMGIK SNTA ++FE+ KIP ENVLG EG+GFKVAMNILNNGRFGM A LSGTM+ CI++A  HA  RV F  K+  Y  +QEKLA M + QY TESMAF IS NMD   +D+ +EAAISK+YASE+AWY  DEAIQILGGMGYM + GLE+ +RD+RIFRIFEG+NDILRLF+   G+ + G   K    LQ  F   S++              T G     L   V  EL   AK  A  I LFG +  ++L ++ K+I+N+Q++L  LA+  + IY + V  SR+S A+  + P+A ++  + K   +    R + +L      +    NE I +IA+  +++ GV 
Sbjct:   35 RSKEKASENESFMANIFRGSLVSSQVFPYPDVLTAEQKELTNSLIDPFERFFSDVNDAARNDANSKIDDTTSTALWELGAFGIQVPSEFGGLGLNNTQYGRLCAIVGVNDLGLGITIGAHQSIGFKGILLYGTPEQKEKYLPKVAAEQVYAAFALTEPSSGSDAGSIRCRAVKSADGKHYVLNGSKIWISNGGIAEIMTVFAQTEQVDPKTGEKKDKVTAFIVERSFGGVTNGPPEKKMGIKASNTAEVYFEDVKIPIENVLGKEGDGFKVAMNILNNGRFGMGATLSGTMKKCIEQATEHANNRVQFGQKLKNYGSIQEKLAQMNILQYATESMAFTISQNMDAGSKDYHLEAAISKIYASESAWYVCDEAIQILGGMGYMVDNGLERVLRDLRIFRIFEGTNDILRLFIALTGIQYAGSHLKE---LQRAFKNPSANLGLIFKEASRRAASTVGLGGTDLSGHVVGELLPYAKKTAHCIDLFGQSVEELLLRYNKNIVNEQILLTRLANAAIDIYAMVVTQSRSSRAVNLNLPTAQHELNMTKALTIQASDRVIKNLQAATSSHHRSLNEKISTIAKTTLENGGVT 619          

Query:  131 RRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLSSSF-------------TYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVK-FALSNVRRYVTDLNLVDIHY----NETIKSIAEHLVQSEGVV 1825
            R     S ++SF  ++F G +  +Q+FP+P VL+ EQ+E    +I P  +FF +VN+ A+ND    I+  +   L +LGAFG+QVP E+GG+GLNNTQY RL  IVG  D+G+GI +GAHQSIGFKGILLYGT EQK KYLP +A+ +  AA+ LTEPS+GSDA +I+ +A KSADG HY+LNGSK+WISNGGI EI TVFA+T   D KT     K+TAFIV+R FGG+++ PPEKKMGIK SNTA ++FE+ KIP ENVLG EG+GFKVAMNILNNGRFGM A LSGTM+ CI++A  HA  RV F  K+  Y  +QEKLA M + QY TESMAF IS NMD   +D+ +EAAISK+YASE+AWY  DEAIQILGGMGYM + GLE+ +RD+RIFRIFEG+NDILRLF+   G+ + G   K    LQ  F   S++              T G     L   V  EL   AK  A  I LFG +  ++L ++ K+I+N+Q++L  LA+  + IY + V  SR+S A+  + P+A ++  + K   +    R + +L      +    NE I +IA+  +++ GV 
Sbjct:   35 RSKEKASENESFMANIFRGSLVSSQVFPYPDVLTAEQKELTNSLIDPFERFFSDVNDAARNDANSKIDDTTSTALWELGAFGIQVPSEFGGLGLNNTQYGRLCAIVGVNDLGLGITIGAHQSIGFKGILLYGTPEQKEKYLPKVAAEQVYAAFALTEPSSGSDAGSIRCRAVKSADGKHYVLNGSKIWISNGGIAEIMTVFAQTEQVDPKTGEKKDKVTAFIVERSFGGVTNGPPEKKMGIKASNTAEVYFEDVKIPIENVLGKEGDGFKVAMNILNNGRFGMGATLSGTMKKCIEQATEHANNRVQFGQKLKNYGSIQEKLAQMNILQYATESMAFTISQNMDAGSKDYHLEAAISKIYASESAWYVCDEAIQILGGMGYMVDNGLERVLRDLRIFRIFEGTNDILRLFIALTGIQYAGSHLKE---LQRAFKNPSANLGLIFKEASRRAASTVGLGGTDLSGHVVGELLPYAKKTAHCIDLFGQSVEELLLRYNKNIVNEQILLTRLANAAIDIYAMVVTQSRSSRAVNLNLPTAQHELNMTKALTIQASDRVIKNLQAATSSHHRSLNEKISTIAKTTLENGGVT 619          

Query:  254 QQMIPPIVKFF---EEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLV 1351
             QM+    + F   E   N AK D       K ++ + +LG   + +PEE GG GL+   YA  +E +       G+ +  + S+    +L +G   QK  Y+    +G+++  + L+EP  GSDA A    A    D  H++LNG+K WI+N    E   VFA T        I+AFIV +   G S    E K+GI+ S+T  L FE+C +P EN+LG  G GFK+AM  L+ GR G+A    G  ++ ++ AV +A +R  F   I +   +Q+K+A M+L       + +  +   D+K Q +  EAA++K+ ASEAA  C  + IQILGGMGY+ +   E+  RD RI  I+EG+++I RL + 
Sbjct:   31 HQMLQKSCRDFANNELSGNAAKFDREHLYPEKQIRQMGELGVMAVAIPEELGGTGLDYVAYAIAMEEISRGCASAGVIMSVNNSLYLGPLLSFGNDAQKKDYITPFTTGERVGCFALSEPGNGSDAGAASTIATDKGD--HFVLNGTKAWITNAFEAEAAIVFATTNKQLKHKGISAFIVPKATKGFSLGKKEDKLGIRGSSTCQLIFEDCVVPKENMLGEPGFGFKIAMQTLDAGRIGIAGQALGIGQAALELAVDYAQKRQAFGKPIAKLQSIQQKIADMSLAMESARLLTWRAAWLKDQK-QPYTKEAAMAKLAASEAATLCSHQCIQILGGMGYVTDMAAERHYRDARITEIYEGTSEIQRLVIA 396          

Query:  128 VRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENL-QQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDI 1333
            VR  ++ +  +S A+S   G           + + KE    L Q+ I P+VK         K D     +P  ++ + + G  G+++  E GG G N      +VE +   D  V   +  H ++    ++ +G  EQKAKYLP LA  +   ++ LTEP AGSDA +++  A K  DGSHY++NGSK+WISN  +  +F +FA    +D    IT FIVDRE  G+  + PE K+GI+ S T  L F+N ++P EN+LG  G+G+K A   LN GR G+AA + G  +      + + +ER  F   I  +  +Q ++AT+A +      M +  +   ++ V  FQ EAA++K YASE A     + +  +GG+G+ ++   EK  RD++I  I+EG+ ++
Sbjct:   10 VRMLANAARQQSAAMSSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLVK---------KMDFEHKFDPSVVKAVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKFGNAEQKAKYLPKLAQ-EYAGSFALTEPGAGSDAFSLKTVAKK--DGSHYVINGSKMWISNSDVAGVFLIFANAKPEDGYRGITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFDNVRVPEENILGTFGHGYKYAAGFLNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAARLQEQGVP-FQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNM 399          

Query:  290 EVNNPAKNDELETIEP-KSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISN-----GGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKK 1381
            E+   A++ + E + P + ++ L +LG   + V EEYGG GL+   YA  +E V   D  V I +G + ++    +  +GT++QK  +L     G+ IA Y L+EP  GSDA A  A       G  Y +NG+K WISN     GGI  +F    K+M       ITAF+  ++  G+S +  E KMG++ ++T  L  E+  +P   VLG  G+GFK+AM  L+ GR G+AA  +G  ++ ++ AV ++ +RV F   +    ++Q+KLA MA +  I+  + +  +   D  +     EAA++K++ASE+A +C  + IQILGGMGY  +   E   R+ R+  I+EG+++I R+ +    +  LGK+
Sbjct:   55 ELAPKARHHDREELYPAEQVRRLGELGLMSVTVREEYGGSGLDYQAYAIGMEEVARGDAAVSIVMGVN-NLYLGAVQQHGTEQQKQDFLVPYTQGEHIAFYALSEPGNGSDAGA--ASTTAKLQGDSYQINGTKAWISNSKEASGGI--VFATVDKSM---KHKGITAFLTPKDVPGLSIAKKESKMGMRATSTCQLVLEDVHVPRSRVLGAAGDGFKIAMQSLDCGRIGIAAQATGIAQAALELAVDYSQKRVAFGKHLARLQLIQQKLADMATRVEISRLLTWRAAWLKDNGL-PITKEAAMAKLHASESATFCAHQCIQILGGMGYTTDLPAELYYRNARVTEIYEGTSEIQRIVIANAVLRELGKE 415          

Query:  155 SKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-----NNLLQNV-------------FSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKFALSNV-RRYVTDLNLVDIHYN----ETIKSIAEHLVQSEGVVQQNPLGF 1846
            SKSFA+++F G++  +Q+FP+P VL++EQ + L++++ P  KFFEEVN+P KND LE +E  ++Q LK++GAFGLQVP + GG+GL NTQYARLVEIVG +D+GVGI LGAHQSIGFKGILL+G  +QK KYLP LA+G+ IAA+CLTEP++GSDA +I+  A +S  G +Y +NGSK+WISNGG  EIFTVFAKT   D KT     KITAFIV+R FGG+S  PPEKKMGIK SNTA ++FEN ++PA+ VLG  G GFKVAMNILNNGRFGMAA LSGTM+  I KAV HA  R  F  KI  Y  +QEK+A MA+ QY+TESMA+ +SGNMD    +FQ+EAAISK++ASEAAW   DE IQ++GGMG+MK+ G+E+ +RD+RIFRIFEG+NDILRLF+   G  + G + K+      N L N               +GL S  T       L  +VHPEL +S +L    I  FG    ++L KH K II++Q +LK +AD  + +Y + V LSRAS ++     SA ++  L +   +    R + D+  +    +    + +++I+  +V++ GVV  +PLGF
Sbjct:   75 SKSFAVNMFKGQISTSQVFPYPSVLNEEQSQFLRELVGPCSKFFEEVNDPMKNDALEKVEEHTLQGLKEMGAFGLQVPADLGGVGLTNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGNPQQKEKYLPKLATGENIAAFCLTEPASGSDAASIKTTAVRSPCGQYYTMNGSKIWISNGGTAEIFTVFAKTPVKDEKTGEMKDKITAFIVERSFGGVSSGPPEKKMGIKASNTAEVYFENVRVPADCVLGEVGGGFKVAMNILNNGRFGMAAALSGTMKGVITKAVDHAANRTQFGNKIHNYGAIQEKMARMAMLQYVTESMAYMVSGNMDSGATEFQIEAAISKIFASEAAWLVTDECIQVMGGMGFMKDAGVERVLRDLRIFRIFEGTNDILRLFVALNGFQNAGNQLKSLQKALKNPLGNAGMLAGEITKRAKRRAGLGSGLT-------LQGTVHPELNHSGELTVKAIEQFGAVIEELLLKHGKKIIDEQFVLKRVADCAIDLYAMVVVLSRASRSLSQGHSSAQHEKMLCETWCTEAHERVMQDIKFLRSGTSKQTFKNLRAISAAVVENGGVVAPHPLGF 659          

Query:  155 SKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-----NNLLQNV-------------FSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKFALSNV-RRYVTDLNLVDIHYN----ETIKSIAEHLVQSEGVVQQNPLGF 1846
            SKSFA+++F G++  +Q+FP+P VL++EQ + L++++ P  KFFEEVN+P KND LE +E  ++Q LK++GAFGLQVP + GG+GL NTQYARLVEIVG +D+GVGI LGAHQSIGFKGILL+G  +QK KYLP LA+G+ IAA+CLTEP++GSDA +I+  A +S  G +Y +NGSK+WISNGG  EIFTVFAKT   D KT     KITAFIV+R FGG+S  PPEKKMGIK SNTA ++FEN ++PA+ VLG  G GFKVAMNILNNGRFGMAA LSGTM+  I KAV HA  R  F  KI  Y  +QEK+A MA+ QY+TESMA+ +SGNMD    +FQ+EAAISK++ASEAAW   DE IQ++GGMG+MK+ G+E+ +RD+RIFRIFEG+NDILRLF+   G  + G + K+      N L N               +GL S  T       L  +VHPEL +S +L    I  FG    ++L KH K II++Q +LK +AD  + +Y + V LSRAS ++     SA ++  L +   +    R + D+  +    +    + +++I+  +V++ GVV  +PLGF
Sbjct:   75 SKSFAVNMFKGQISTSQVFPYPSVLNEEQSQFLRELVGPCSKFFEEVNDPMKNDALEKVEEHTLQGLKEMGAFGLQVPADLGGVGLTNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGNPQQKEKYLPKLATGENIAAFCLTEPASGSDAASIKTTAVRSPCGQYYTMNGSKIWISNGGTAEIFTVFAKTPVKDEKTGEMKDKITAFIVERSFGGVSSGPPEKKMGIKASNTAEVYFENVRVPADCVLGEVGGGFKVAMNILNNGRFGMAAALSGTMKGVITKAVDHAANRTQFGNKIHNYGAIQEKMARMAMLQYVTESMAYMVSGNMDSGATEFQIEAAISKIFASEAAWLVTDECIQVMGGMGFMKDAGVERVLRDLRIFRIFEGTNDILRLFVALNGFQNAGNQLKSLQKALKNPLGNAGMLAGEITKRAKRRAGLGSGLT-------LQGTVHPELNHSGELTVKAIEQFGAVIEELLLKHGKKIIDEQFVLKRVADCAIDLYAMVVVLSRASRSLSQGHSSAQHEKMLCETWCTEAHERVMQDIKFLRSGTSKQTFKNLRAISAAVVENGGVVAPHPLGF 659          

Query:  149 SSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDS----KTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRK-VQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLG-------KKYKNNNL------LQNVFSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVAL----SRASMAMENSEPSASYQCTLVK-------FALSNVRRYVTDLNLVDIHYNETIKSIAEHLVQSEGVVQQNPL 1840
            S S ++A  LF GKV+  ++FP+P++ S E+ E L Q + P+ KFF E  + AK D    I P+++  LK+LG FG+Q+PEEYGG+GL+NT YARL EI  + D  + + L AHQ+IG KGIL+ GT  QKAKYLP LA+G+ IAA+CLTEP +GSDA +IQ +A  + DG HY+LNG+K WISNGG  +I TVFA+T   D     K KITAFIV+R FGG++   PE K+GI+ SNT  + FE+ K+P ENV+G  G+GFKVAMNILNNGRF M    +G ++  I+ +  +A  R  F  ++ E+ M+Q+K ATMAL  Y+ ESMA+  +G MDR  + D  +EAA+ KV++SE  W CV EA+Q+LGG+G+ K    E+ +RD RI +IFEG+N+ILR+++   GM + G       K+ K  NL      L         +  +G   K  +  VHP L  SAK+     + FG     +L ++ K I+++QL+LK +AD ++ +Y ++  L       S+ + N +       T  K       + LS ++RY  +      + +  IK IA+ ++     +  +PL
Sbjct:   44 SRSLAYAKDLFLGKVNKKEVFPYPEI-SNEELEELNQFVQPVEKFFNESVDSAKIDREANIPPETLDGLKELGLFGIQIPEEYGGLGLSNTMYARLGEIT-SLDGSIAVTLAAHQAIGLKGILIAGTDAQKAKYLPKLATGEHIAAFCLTEPGSGSDAASIQLRATLTEDGKHYLLNGTKFWISNGGWADIMTVFARTEVVDKDGQKKDKITAFIVERAFGGVTSGKPEDKLGIRGSNTTEITFEDTKVPIENVIGEVGDGFKVAMNILNNGRFSMGGAGAGVVKKLIELSAEYAGTRKQFNRRLSEFGMIQDKFATMALNVYVMESMAYLTAGMMDRPGLPDCSLEAAMVKVFSSEGTWICVSEALQVLGGLGFTKNYPYERYLRDCRILQIFEGTNEILRMYVALTGMQYAGKILTGKIKEMKKGNLGVVFEILGKKIKDTVQTADFGLTGKDGV--VHPSLTESAKMFEQNAACFGSTVEGLLYRYGKTIVDEQLLLKKVADVLINLYAMTAVLSRSSRSISIGLRNHDHEVLLTNTFCKDAHFKNNYMLSQLQRYSPE------NDDANIKKIAQDVLAKRAYICSHPL 626          

Query:  191 VDC-TQIFPFP---KVLSKEQEENLQQMIPPIVKFFEEVNN-PAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLV 1351
            V C TQ+   P   +++ +   +  Q+ + PI    ++ +  PAK           +Q L  +G   ++VPE  GG G++   Y   VE +       G+ +  + S+    IL +G++EQK +++    +G+K+  + L+EP  GSDA A    A +  +G+ ++LNG+K WI+N        VFA T        I+AF+V     G+S    E K+GI+ S+TA +  E+C+IP  N+LG  G GFK+AM  L++GR G+AA   G  ++ +  A  +A +R  F   I +   +Q KLA MA+       + +  +   D K + F  EAA++K+ ASEAA +   +AIQ+LGGMGY+ +   E+  RD RI  I+EG+++I RL + 
Sbjct:   18 VRCLTQLAELPELHQMMRQTCRDYAQKELAPIAGLLDKEHRFPAKQ----------VQELGAMGVMAVEVPESLGGAGMDYLAYCLAVEELSRGCASTGVIVSVNNSLYIGPILKFGSEEQKKQWITPFTTGEKVGCFALSEPGNGSDAGAASTLAQQ--EGNEWVLNGTKAWITNSWDASATVVFATTDKSLKHKGISAFLVPMPHPGLSLGKKEDKLGIRASSTANIILEDCRIPLGNMLGERGMGFKIAMQTLDSGRLGIAAQALGIAQAALDCAADYAHKRTAFGAPIGKLQAIQFKLADMAVAIESARLLTWKAALLRDAK-KPFTKEAAMAKLAASEAATFASHQAIQVLGGMGYVTDMPAERHYRDARITEIYEGTSEIQRLVIA 396          

Query:  359 DLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDD---SKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAF---AISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFL 1348
            +LG     +PE+ GG+GL       + E +     GV  A+ A+ S+G   +++ G   Q+ KYL  +     + AYC+TEP AGSD   I+ +A K  D   Y++NG K+WI+NGG    + + A+T  D    +    T FIVD +  G+     E  MG +CS+T  + FE+  IP ENVL GEG GFK+AM   +  R  +AAG +G  +  +++A  +AMER TF   I E+  V   LA MA+K  +   MA+   A   +M R+   +   A+I+K +A + A  C  +A+QI GG G+  E  +EK MRD +I++I+EG+  I RL +
Sbjct:   88 ELGLMNGHIPEDCGGMGLGIFDACLITEELAYGCTGVQTAIEAN-SLGQMPVIIAGNDAQRKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTRAVKKGD--DYVINGQKMWITNGGKANWYFLLARTDSDPKCPASKAFTGFIVDADTPGVQPGRKELNMGQRCSDTRGITFEDVVIPKENVLIGEGAGFKIAMGAFDKTRPPVAAGATGLAQRALEEATKYAMERKTFGKFIAEHQAVSFLLAEMAMKVELAR-MAYQRAAWEVDMGRRNTYY---ASIAKAFAGDIANQCASDAVQIFGGNGFNSEYPVEKLMRDAKIYQIYEGTAQIQRLII 416          

Query:  362 LGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN 1390
            +G   ++VPEE GG GL+   Y+  VE +       G+ +  + S+    IL +G++EQK +++    SG KI  + L+EP  GSDA A    A    DG  ++LNG+K WI+N        V A T        I+AF+V+    G+S    E K+GI+ S+TA L FE+C+IP +N+LG  G GFK+AM  L+ GR G+A+   G  ++ +  AV +A +R+ F   I +   +Q KLA MAL       + +  +   D K + F  EAA++K+ ASEAA     +AIQILGGMGY+ +   E+  RD RI  I+EG+++I RL +  Q    L K+Y++
Sbjct:   64 IGLLAVEVPEELGGAGLDYLAYSIAVEEISRGCASTGVIMSVNNSLYLGPILKHGSEEQKRQWISPFCSGDKIGCFALSEPGNGSDAGAASTTA--KLDGEEWVLNGTKSWITNAWDASAAVVLATTDKSLKHKGISAFLVEMPTPGLSLGKKEDKLGIRASSTANLIFEDCRIPRQNLLGQPGMGFKIAMQTLDAGRIGIASQALGIGQAALDCAVDYAEKRLAFGAPISKLQAIQFKLADMALALESARLLTWRAAMMKDNK-KPFTKEAAMAKLAASEAATQISHQAIQILGGMGYVSDMPAERHYRDARITEIYEGTSEIQRLVIANQ----LLKEYRS 399          

Query:  362 LGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN 1390
            +G   ++VPEE GG GL+   Y+  VE +       G+ +  + S+    IL +G++EQK +++    SG KI  + L+EP  GSDA A  A      DG  ++LNG+K WI+N        V A T        I+AF+V+    G+S    E K+GI+ S+TA L FE+C+IP +N+LG  G GFK+AM  L+ GR G+A+   G  ++ +  AV +A +R+ F   I +   +Q KLA MAL       + +  +   D K + F  EAA++K+ ASEAA     +AIQILGGMGY+ +   E+  RD RI  I+EG+++I RL +  Q    L K+Y++
Sbjct:   74 IGLLAVEVPEELGGAGLDYLAYSIAVEEISRGCASTGVIMSVNNSLYLGPILKHGSEEQKRQWISPFCSGDKIGCFALSEPGNGSDAGA--ASTTAKLDGEEWVLNGTKSWITNAWDASAAVVLATTDKSLKHKGISAFLVEMPTPGLSLGKKEDKLGIRASSTANLIFEDCRIPRQNLLGQPGMGFKIAMQTLDAGRIGIASQALGIGQAALDCAVDYAEKRLAFGAPISKLQAIQFKLADMALALESARLLTWRAAMMKDNK-KPFTKEAAMAKLAASEAATQISHQAIQILGGMGYVSDMPAERHYRDARITEIYEGTSEIQRLVIANQ----LLKEYRS 409          

Query:  362 LGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN 1390
            +G   ++VPEE GG GL+   Y+  VE +       G+ +  + S+    IL +G++EQK +++    SG KI  + L+EP  GSDA A  A      DG  ++LNG+K WI+N        V A T        I+AF+V+    G+S    E K+GI+ S+TA L FE+C+IP +N+LG  G GFK+AM  L+ GR G+A+   G  ++ +  AV +A +R+ F   I +   +Q KLA MAL       + +  +   D K + F  EAA++K+ ASEAA     +AIQILGGMGY+ +   E+  RD RI  I+EG+++I RL +  Q    L K+Y++
Sbjct:   77 IGLLAVEVPEELGGAGLDYLAYSIAVEEISRGCASTGVIMSVNNSLYLGPILKHGSEEQKRQWISPFCSGDKIGCFALSEPGNGSDAGA--ASTTAKLDGEEWVLNGTKSWITNAWDASAAVVLATTDKSLKHKGISAFLVEMPTPGLSLGKKEDKLGIRASSTANLIFEDCRIPRQNLLGQPGMGFKIAMQTLDAGRIGIASQALGIGQAALDCAVDYAEKRLAFGAPISKLQAIQFKLADMALALESARLLTWRAAMMKDNK-KPFTKEAAMAKLAASEAATQISHQAIQILGGMGYVSDMPAERHYRDARITEIYEGTSEIQRLVIANQ----LLKEYRS 412          

Query:  362 LGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN 1390
            +G   ++VPEE GG GL+   Y+  VE +       G+ +  + S+    IL +G++EQK +++    SG KI  + L+EP  GSDA A  A      DG  ++LNG+K WI+N        V A T        I+AF+V+    G+S    E K+GI+ S+TA L FE+C+IP +N+LG  G GFK+AM  L+ GR G+A+   G  ++ +  AV +A +R+ F   I +   +Q KLA MAL       + +  +   D K + F  EAA++K+ ASEAA     +AIQILGGMGY+ +   E+  RD RI  I+EG+++I RL +  Q    L K+Y++
Sbjct:   67 IGLLAVEVPEELGGAGLDYLAYSIAVEEISRGCASTGVIMSVNNSLYLGPILKHGSEEQKRQWISPFCSGDKIGCFALSEPGNGSDAGA--ASTTAKLDGEEWVLNGTKSWITNAWDASAAVVLATTDKSLKHKGISAFLVEMPTPGLSLGKKEDKLGIRASSTANLIFEDCRIPRQNLLGQPGMGFKIAMQTLDAGRIGIASQALGIGQAALDCAVDYAEKRLAFGAPISKLQAIQFKLADMALALESARLLTWRAAMMKDNK-KPFTKEAAMAKLAASEAATQISHQAIQILGGMGYVSDMPAERHYRDARITEIYEGTSEIQRLVIANQ----LLKEYRS 402          

Query:  362 LGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN 1390
            +G   ++VPEE GG GL+   Y+  VE +       G+ +  + S+    IL +G++EQK +++    SG KI  + L+EP  GSDA A  A      DG  ++LNG+K WI+N        V A T        I+AF+V+    G+S    E K+GI+ S+TA L FE+C+IP +N+LG  G GFK+AM  L+ GR G+A+   G  ++ +  AV +A +R+ F   I +   +Q KLA MAL       + +  +   D K + F  EAA++K+ ASEAA     +AIQILGGMGY+ +   E+  RD RI  I+EG+++I RL +  Q    L K+Y++
Sbjct:   74 IGLLAVEVPEELGGAGLDYLAYSIAVEEISRGCASTGVIMSVNNSLYLGPILKHGSEEQKRQWISPFCSGDKIGCFALSEPGNGSDAGA--ASTTAKLDGEEWVLNGTKSWITNAWDASAAVVLATTDKSLKHKGISAFLVEMPTPGLSLGKKEDKLGIRASSTANLIFEDCRIPRQNLLGQPGMGFKIAMQTLDAGRIGIASQALGIGQAALDCAVDYAEKRLAFGAPISKLQAIQFKLADMALALESARLLTWRAAMMKDNK-KPFTKEAAMAKLAASEAATQISHQAIQILGGMGYVSDMPAERHYRDARITEIYEGTSEIQRLVIANQ----LLKEYRS 409          

Query:   89 VLKHVHNKNFTSCVRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIKS------------VHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDLNLVDIHYN--ETIKSIAEHLVQSEGVVQQNPLG 1843
            VL      +  +  R     + SKSFA+ +F G++   Q+FP+P VLS+EQ + L++++ P+ +FFEEVN+PAKND LE +E  ++Q LK+LGAFGLQVP E GG+GL+NTQYARL EIVG +D+GV + LGAHQSIGFKGILLYGTK Q+ KYLP +ASG+ +AA+CLTEPS+GSD  +I++ A  S  G +Y LNGSK+WISNGG+ +IFTVFAKT   D+ T     KITAF+V+R FGG++H  PEKKMGIK SNT+ ++F+  K+P+ENVLG  G+GFKVA+NILNNGRFGMAA L+GTM+S I KAV HA  R  F  KI  + ++QEKLA MA+ QY+TESMA+ +S NMD+  +DFQ+EAAISK++ SEAAW   DE IQI+GGMG+MKE G+E+ +RD+RIFRIFEG+NDILRLF+  QG +  GK+     N L+N F  +      G   KQL +             VHPEL  S +L    +  F       L KH+K I+N+Q +L+ LAD  + +Y + V LSRAS ++    P+A ++  L       A + +R  +  L     H       +SI++ +V++ G+V  NPLG
Sbjct:   49 VLDKPETLSSDASTREKPARAESKSFAVGMFKGQLTIDQVFPYPSVLSEEQAQFLKELVGPVARFFEEVNDPAKNDALEKVEDDTLQGLKELGAFGLQVPSELGGLGLSNTQYARLAEIVGMHDLGVSVTLGAHQSIGFKGILLYGTKAQREKYLPRVASGQALAAFCLTEPSSGSDVASIRSSAIPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPIKDAATGAVKEKITAFVVERSFGGVTHGLPEKKMGIKASNTSEVYFDGVKVPSENVLGEVGDGFKVAVNILNNGRFGMAATLAGTMKSLIAKAVDHATNRTQFGDKIHNFGVIQEKLARMAILQYVTESMAYMLSANMDQGFKDFQIEAAISKIFCSEAAWKVADECIQIMGGMGFMKEPGVERVLRDIRIFRIFEGANDILRLFVALQGCMDKGKELTGLGNALKNPFGNV--GLLMGEAGKQLRRRTGIGSGLSLSGIVHPELSRSGELAVQALDQFATVVEAKLVKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGYPTAQHEKMLCDSWCIEAATRIRENMASLQSSPQHQELFRNFRSISKAMVENGGLVTGNPLG 655          

Query:  155 SKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIKS------------VHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDLNLVDIHYN--ETIKSIAEHLVQSEGVVQQNPLG 1843
            SKSFA+ +F G++   Q+FP+P VLS+EQ + L++++ P+ +FFEEVN+PAKND LE +E  ++Q LK+LGAFGLQVP E GG+GL+NTQYARL EIVG +D+GV + LGAHQSIGFKGILLYGTK Q+ KYLP +ASG+ +AA+CLTEPS+GSD  +I++ A  S  G +Y LNGSK+WISNGG+ +IFTVFAKT   D+ T     KITAF+V+R FGG++H  PEKKMGIK SNT+ ++F+  K+P+ENVLG  G+GFKVA+NILNNGRFGMAA L+GTM+S I KAV HA  R  F  KI  + ++QEKLA MA+ QY+TESMA+ +S NMD+  +DFQ+EAAISK++ SEAAW   DE IQI+GGMG+MKE G+E+ +RD+RIFRIFEG+NDILRLF+  QG +  GK+     N L+N F  +      G   KQL +             VHPEL  S +L    +  F       L KH+K I+N+Q +L+ LAD  + +Y + V LSRAS ++    P+A ++  L       A + +R  +  L     H       +SI++ +V++ G+V  NPLG
Sbjct:   49 SKSFAVGMFKGQLTIDQVFPYPSVLSEEQAQFLKELVGPVARFFEEVNDPAKNDALEKVEDDTLQGLKELGAFGLQVPSELGGLGLSNTQYARLAEIVGMHDLGVSVTLGAHQSIGFKGILLYGTKAQREKYLPRVASGQALAAFCLTEPSSGSDVASIRSSAIPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPIKDAATGAVKEKITAFVVERSFGGVTHGLPEKKMGIKASNTSEVYFDGVKVPSENVLGEVGDGFKVAVNILNNGRFGMAATLAGTMKSLIAKAVDHATNRTQFGDKIHNFGVIQEKLARMAILQYVTESMAYMLSANMDQGFKDFQIEAAISKIFCSEAAWKVADECIQIMGGMGFMKEPGVERVLRDIRIFRIFEGANDILRLFVALQGCMDKGKELTGLGNALKNPFGNV--GLLMGEAGKQLRRRTGIGSGLSLSGIVHPELSRSGELAVQALDQFATVVEAKLVKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGYPTAQHEKMLCDSWCIEAATRIRENMASLQSSPQHQELFRNFRSISKAMVENGGLVTGNPLG 633          

Query:  110 KNFTSCVRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTM---GDDSKT-KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRK-VQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLG-------KKYKNNN---LLQNVFSGLSSSF--TYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVK-FALSNVRRYVTDLNLVDI----HYNETIKSIAEHLVQSEGVVQQNPL 1840
            + FT+  R       S SFA  LF G ++   +FPFP+V   E  E + Q + P+ KFF E  +  K D+   I   +++ LK LG FG+QVPEEYGG+GL+NT YARL EI+ + D  + + L AHQ+IG KGI+L G +EQKAKYLP L+SG+ IAA+CLTEP++GSDA +IQ +A  S D  ++ILNGSK+WI+NGG+  IFTVFAKT     D SKT K+TAFIV+R+FGGI++  PE K+GI+ SNT  + FEN ++P ENVLG  G GFKVAMNILN+GRF M + ++G ++  I+    +A  R  F   + E+ ++QEK A MA K Y+ ESMA+  SG +D+    D  +EAA+ KV++SEAAW CV EA+QILGG GYMK+   E+ +RD RI  IFEG+N+ILRLF+   G+ H G       K+ K+ N   +++ +   L  S   T        +  VHP L +SA  L   +  FG     +L +  K+I+ +QL+LK +A+ ++ +YG++  LSRAS ++     +  ++  L   F +    + +  L+ +D     + +E IK ++  +++    +  +PL
Sbjct:   25 REFTARRRPLHTSLQSCSFAKELFLGNIEQKGVFPFPEVSQHELSE-INQFVGPLEKFFTEEVDSRKIDQEGKIPVDTLEKLKSLGLFGIQVPEEYGGLGLSNTMYARLGEII-SLDASITVTLAAHQAIGLKGIILVGNEEQKAKYLPKLSSGEHIAAFCLTEPASGSDAASIQTRATLSEDKKYFILNGSKVWITNGGLANIFTVFAKTEVVDSDGSKTDKMTAFIVERDFGGITNGKPEDKLGIRGSNTCEVHFENTRVPVENVLGEVGGGFKVAMNILNSGRFSMGSAVAGMLKKLIELTAEYACTRKQFNRNLSEFGLIQEKFALMAQKAYVMESMAYLTSGMLDQPGFPDCSIEAAMVKVFSSEAAWQCVSEALQILGGSGYMKDYPYERMLRDARILLIFEGTNEILRLFIALTGLQHAGRILTSRIKELKSGNVTTVMETIGRKLRDSLGRTVDLGLTGDLGVVHPSLGDSANKLEENVHYFGRTVETLLLRFGKNIVEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANMFCVEAYFQNLFSLSQLDKNAPENLDEQIKKVSRQILEKRAYICAHPL 621          

Query:  254 QQMIPPIVKFFEE---VNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN 1390
             QM+    + F E   V   A+ D         ++ + +LG   + VPEE  G GL+   Y+  +E +       G+ +  + S+    IL +G+ +QK +++    +G KI  + L+EP  GSDA A    A +  +G  ++LNG+K WI+N        VFA T        I+AF+V     G++    E K+GI+ S+TA L FE+C+IP EN+LG  G GFK+AM  L+ GR G+A+   G  ++ +  AV +A  R  F   + +   +Q KLA MAL       + +  +   D K + F  E+A++K+ ASEAA     +AIQILGGMGY+ E   E+  RD RI  I+EG+++I RL +      HL + Y++
Sbjct:   38 HQMLRQTCRDFAEKELVPIAAQLDREHLFPTAQVKKMGELGLLAMDVPEELSGAGLDYLAYSIALEEISRACASTGVIMSVNNSLYLGPILKFGSAQQKQQWITPFTNGDKIGCFALSEPGNGSDAGAASTTARE--EGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENRNAFGAPLTKLQNIQFKLADMALALESARLLTWRAAMLKDNK-KPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEGTSEIQRLVIAG----HLLRSYRS 412          

Query:  260 MIPPIVKFFEEVNNP--AKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQ---DFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDI 1333
            M   + KF +E   P  +  DE   +E   +Q L   G  G++V  +YGG   +      ++E +   D  V +      +I       + ++EQKA YLP L + +K+ ++CL+E  AGSD+ A++ +ADKS  G++Y+LNGSK+WIS+    E+F VFA          IT F+VDR+  G      E KMGI+ S+T  L FEN K+P  N+LG  G+G+K A+  LN GR G+AA + G  + C    + +  ER+ F  +I ++  +Q ++A +A +   T  + +    N  R V+    F  EA+++K YASE A     + I+ +GG+GY K+  +EK  RD +I  I+EG+++I
Sbjct:   64 MKQTVKKFAQEHVAPLVSSMDENSKMEKSVIQGLFQQGLMGIEVEAQYGGTEASFFCSVLVIEELAKVDASVALLCDIQNTIINNLFRKHASEEQKATYLPKLVT-EKLGSFCLSEAGAGSDSFAMKTRADKS--GNYYVLNGSKMWISHAEHAELFLVFANVDPSSGYRGITCFLVDRDTEGFQIGKRENKMGIRASSTCQLTFENVKVPETNILGKIGHGYKYAIGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERMQFGKRIFDFQGLQHQVAQVATQLEATRLLTY----NAARLVEAGRPFIKEASMAKYYASEVAGLTTSKCIEWMGGVGYTKDYPVEKFFRDAKIGTIYEGASNI 419          

Query:  149 SSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIKS------------VHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDLNLVDIHYNE---TIKSIAEHLVQSEGVVQQNPLGF 1846
            S SKSFA+  F G++   Q+FP+P VL+++Q + L++++ P+ +FFEEVN+ AKND LE +E  +MQ LK+LGAFGLQVP E GG+GL NTQYARLVEIVG YD+GVGI LGAHQSIGFKGILL+GTK QK KYLP LASG+ IAA+CLTEPS+GSDA +I++ A  S  G +Y LNGSK+WISNGG+ +IFTVFAKT   D+ T     KITAF+V+R FGG++H PPEKKMGIK SNTA ++F+  ++PAENVLG  G GFKVAM+ILNNGRFGMAA L+GTM+  I KAV HA  R  F  KI  + ++QEKLA MA+ QY+TESMA+ +S NMD+   DFQ+EAAISK++ SEAAW   DE IQI+GGMG+MKE G+E+ +RD+RIFRIFEG+NDILRLF+  QG +  GK+     N L+N F   ++    G   KQL +             VH EL  S +L    +  F       L KH+KDIIN+Q +L+ LAD  + +Y + V LSRAS ++    P+A ++  L       A + +R  +T L   D    E     KSI++ LV+  GVV  NPLGF
Sbjct:   68 SVSKSFAVGTFKGQLTTDQVFPYPSVLNEDQTQFLKELVGPVTRFFEEVNDAAKNDMLERVEETTMQGLKELGAFGLQVPNELGGVGLCNTQYARLVEIVGMYDLGVGIVLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETIAAFCLTEPSSGSDAASIRSSAVPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPVTDTATGAVKEKITAFVVERSFGGVTHGPPEKKMGIKASNTAEVYFDGVRVPAENVLGEVGGGFKVAMHILNNGRFGMAAALAGTMKGIIAKAVDHAANRTQFGEKIHNFGLIQEKLARMAMLQYVTESMAYMVSANMDQGSTDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGNALKNPFG--NAGLLLGEAGKQLRRRAGLGSGLSLSGIVHQELSRSGELAVQALEQFATVVEAKLIKHKKDIINEQFLLQRLADSAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDSWCIEAAARIRENMTALQ-SDPQQQELFRNFKSISKALVERGGVVTSNPLGF 655          

Query:  122 SCVRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIK------------SVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDLNLVDIHYNE---TIKSIAEHLVQSEGVVQQNPLGF 1846
            +  R+    + SKSFA+ +F G++   Q+FP+P VL++EQ + L++++ P+ +FFEEVN+PAKND LE +E  + Q LK+LGAFGLQVP E GG+GL NTQYARLVEIVG +D+GVGI LGAHQSIGFKGILL+GTK QK KYLP LASG+ +AA+CLTEPS+GSDA +I+  A  S  G +Y LNGSKLWISNGG+ +IFTVFAKT   D  T     KITAF+V+R FGGI+H PPEKKMGIK SNTA +FF+  ++P+ENVLG  G+GFKVAM+ILNNGRFGMAA L+GTMR  I KAV HA  R  F  KI  + ++QEKLA M + QY+TESMA+ +S NMD+   DFQ+EAAISK++ SEAAW   DE IQI+GGMG+MKE G+E+ +RD+RIFRIFEG+NDILRLF+  QG +  GK+     + L+N F   ++    G   KQL +             VHPEL  S +L    +  F       L KH+K I+N+Q +L+ LAD  + +Y + V LSRAS ++    P+A ++  L       A + +R  +  L   D    E     KSI++ LV+  GVV  NPLGF
Sbjct:   59 ALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFG--NAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQ-SDPWQQELYRNFKSISKALVERGGVVTSNPLGF 655          

Query:  149 SSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIKS------------VHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDLNLVDIHYNE---TIKSIAEHLVQSEGVVQQNPLGF 1846
            + SKSFA+++F G++   Q+FP+P VL++EQ E L++++ P+ +FFEEVN+PAKND LE +E  ++Q LK+LGAFGLQVP E GG+GL NTQYARLVEIVG +D+ VGI LGAHQSIGFKGILL+GTK QK KYLP LASG+ +AA+CLTEPS+GSDA +I+  A  S  G +Y LNGSKLWISNGG+ +IFTVFAKT   D  T     KITAF+V+R FGG++H PPEKKMGIK SNTA + F+  ++P+ENVLG  G+GFKVAM+ILNNGRFGMAA L+GTMR  I KAV +A  R+ F  KI  + ++QEKLA M + QY+TESMA+ +S NMD+   DFQ+EAAISK++ SEAAW   DE IQI+GGMG+MKE G+E+ +RD+RIFRIFEG+NDILRLF+  QG +  GK+     + L+N F   ++    G   KQL +             VHPEL  S +L    +  F       L KH+K I+N+Q +L+ LAD  + +Y + V LSRAS ++     +A ++  L       A + +R  +  L   D   +E     KSI++ LV+  GVV  NPLGF
Sbjct:   68 AESKSFAVAMFKGQLTTDQVFPYPSVLNQEQTEFLKELVEPVSRFFEEVNDPAKNDTLEMVEETTLQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLAVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETLAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGVTHGPPEKKMGIKASNTAEVLFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIITKAVDYATNRIQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGSTDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFG--NAGLLLGEAGKQLRRRAGLGSGLSLSGIVHPELSRSGELAVQALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHHTAQHEKMLCDTWCIEAAARIREGMAALQ-SDPRQHELYRNFKSISKALVERGGVVTNNPLGF 655          

Query:   89 VLKHVHNKNFTSCVRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIKS------------VHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDLNLVDIHYN--ETIKSIAEHLVQSEGVVQQNPLG 1843
            VL      +  +  R     + SKSFA+ +F G++   Q+FP+P VLS+EQ + L++++ P+ +FFEEVN+PAKND LE +E  ++Q LK+LGAFGLQVP E GG+GL+NTQYARL EIVG +D+GV + LGAHQSIGFKGILLYGTK Q+ KYLP +ASG+ +AA+CLTEPS+GSD  +I++ A  S  G +Y LNGSK+WISNGG+ +IFTVFAKT   D+ T     KITAF+V+R FGG++H  PEKKMGIK SNT+ ++F+  K+P+ENVLG  G+GFKVA+NILNNGRFGMAA L+GTM+S I KAV HA  R  F  KI  + ++QEKLA MA+ QY+TESMA+ +S NMD+  +DFQ+EAAISK++ SEAAW   DE IQI+GGMG+MKE G+E+ +RD+RIFRIFEG+NDILRLF+  QG +  GK+     N L+N F  +      G   KQL +             VHPEL  S +L    +  F       L KH+K I+N+Q +L+ LAD  + +Y + V LSRAS ++    P+A ++  L       A + +R  +  L     H       +SI++ +V++ G+V  NPLG
Sbjct:   49 VLDKPETLSSDASTREKPARAESKSFAVGMFKGQLTIDQVFPYPSVLSEEQAQFLKELVGPVARFFEEVNDPAKNDALEKVEDDTLQGLKELGAFGLQVPSELGGLGLSNTQYARLAEIVGMHDLGVSVTLGAHQSIGFKGILLYGTKAQREKYLPRVASGQALAAFCLTEPSSGSDVASIRSSAIPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPIKDAATGAVKEKITAFVVERSFGGVTHGLPEKKMGIKASNTSEVYFDGVKVPSENVLGEVGDGFKVAVNILNNGRFGMAATLAGTMKSLIAKAVDHATNRTQFGDKIHNFGVIQEKLARMAILQYVTESMAYMLSANMDQGFKDFQIEAAISKIFCSEAAWKVADECIQIMGGMGFMKEPGVERVLRDIRIFRIFEGANDILRLFVALQGCMDKGKELTGLGNALKNPFGNV--GLLMGEAGKQLRRRTGIGSGLSLSGIVHPELSRSGELAVQALDQFATVVEAKLVKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGYPTAQHEKMLCDSWCIEAATRIRENMASLQSSPQHQELFRNFRSISKAMVENGGLVTGNPLG 655          

Query:   89 VLKHVHNKNFTSCVRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIKS------------VHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKF----ALSNVRRYVTDL--NLVDIHYNETIKSIAEHLVQSEGVVQQNPL 1840
            VL+     +  +  R     + SKSFA+ +F G++   Q+FP+P VL++ Q + L++++ P+ +FFEEVN+PAKND LE +E  ++Q LK+LGAFGLQVP E GG+GL+NTQYARL EIVG +D+GV + LGAHQSIGFKGILLYGTK QK KYLP +ASG+ +AA+CLTEPS+GSD  +I++ A  S  G +Y LNGSK+WISNGG+ +IFTVFAKT   D+ T     KITAF+V+R FGG++H  PEKKMGIK SNT+ ++F+  K+PAENVLG  G+GFKVA+NILNNGRFGMAA L+GTM++ I KAV HA  R  F  KI  + ++QEKLA MA+ QY+TESMA+ +S NMD+  +DFQ+EAAISK++ SEAAW   DE IQI+GGMG+MKE G+E+ +RD+RIFRIFEG+NDILRLF+  QG +  GK+     N L+N    +      G   KQL +             VHPEL  S +L    +  F       L KH+K I+N+Q +L+ LAD  + +Y + V LSRAS ++    P+A ++  L       A + +R  +  L  N          +SI++ +V++ G+V  NPL
Sbjct:   48 VLEKPETLSSDASTREKPARAESKSFAVGMFKGQLTTDQVFPYPSVLNEGQTQFLKELVGPVARFFEEVNDPAKNDSLEKVEEDTLQGLKELGAFGLQVPSELGGLGLSNTQYARLAEIVGMHDLGVSVTLGAHQSIGFKGILLYGTKAQKEKYLPRVASGQALAAFCLTEPSSGSDVASIRSSAVPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPIKDAATGAVKEKITAFVVERSFGGVTHGLPEKKMGIKASNTSEVYFDGVKVPAENVLGEVGDGFKVAVNILNNGRFGMAATLAGTMKAIIAKAVDHATNRTQFGDKIHNFGVIQEKLARMAILQYVTESMAYMLSANMDQGFKDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDIRIFRIFEGTNDILRLFVALQGCMDKGKELTGLGNALKNPLGNV--GLLIGEASKQLRRRTGIGSGLSLSGIVHPELSRSGELAVQALEQFATVVEAKLMKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGYPTAQHEKMLCDSWCIEAATRIRENMASLQSNPQQQELFRNFRSISKAMVENGGLVTSNPL 653          

Query:  131 RRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFS--GLSSSFTYGYNKKQLIKSV--------HPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYNETIK---SIAEHLVQSEGVVQQNPLGF 1846
            ++ + +  SKSFA ++F G V   Q+FP+P+VL++EQ+E LQ ++PP  KFFEEVN+P KND  E IE  +M+ LK+LGA GLQ+PE+ GG+GL NTQYARLVEIVG +D+GVGI LGAHQSIGFKGILLYG  EQKAKYLP  A G+K+AA+CLTEPS+GSDAQ+++ +A  S DG HYILNG K+WISNGGI EIFTVFA+T   D KT     KITAFIV+R FGG++  PPEKKMGIKCSNTA + FE+ K+P ENVLGG G GFKVAMNILNNGRFGMAA LSGTM+  IKKA  HA  RV F   I +Y  +QEKLA MA+ QY+TESMA+ IS NMD+   DF++EAAISKVYASEAAW C DEAIQILGGMGYMKECGLE+ MRD+RIFRIFEG+NDILRL +  QG+ + G+  K    LQN  +  G  ++F     KK L  S         HP L+ +A   +  +  FG A    L KH K++  +Q +LK +AD  + +Y + V LSRAS A+E + P+A+Y+  +           V     V     +  K   +I+  ++   G  QQNPLGF
Sbjct:   51 KKPTGLKESKSFAKNMFRGLVQSDQVFPYPEVLNEEQKETLQTLVPPTAKFFEEVNDPFKNDADEKIEDHTMEGLKELGALGLQIPEDLGGVGLTNTQYARLVEIVGEHDLGVGITLGAHQSIGFKGILLYGNPEQKAKYLPQCAMGEKMAAFCLTEPSSGSDAQSVRTRAVLSEDGKHYILNGGKIWISNGGIAEIFTVFAQTSDVDPKTGGTKDKITAFIVERGFGGVTSGPPEKKMGIKCSNTAEVHFEDVKVPVENVLGGVGGGFKVAMNILNNGRFGMAAALSGTMKGVIKKAAEHAASRVQFGDTIGKYGAIQEKLAKMAMMQYVTESMAYMISANMDQGSLDFEIEAAISKVYASEAAWACTDEAIQILGGMGYMKECGLERVMRDIRIFRIFEGTNDILRLLIAGQGLRYAGQFMK---ALQNPAANIGAVAAFASKRAKKSLGLSTGVSLAEFAHPTLKQAAAQTSAAVEAFGFATEDCLMKHGKNLAAEQFLLKRIADAAIDVYAMVVTLSRASRALEQNSPTAAYEALMCSTYCDEALDRVKIALAVSPRQRQLFKNYAAISNEIISHGGAQQQNPLGF 637          

Query:  149 SSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIIN--QQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYNETIK------SIAEHLVQSEGVVQQNPLGF 1846
            + + SFA+++F G +  + IFPFP+VL++EQEE LQ ++ P  KFFE+VN+ A ND LE +E KS++ LK++GAFGLQVP++ GG+GL NTQYARLVEIVG++D+GVGI LGAHQSIGFKGILLYG+ EQK KYLP LA+GKK+AA+CLTEPS GSDA  I+ +A  S DG+HY LNG K+WISNGG+ +IFTVFAKT   D KT        AFIV+R FGGISH  PEKKMGIK SNTAALF ++CK+P EN+LG  G+GFKVAMNILNNGRFGMAA LSGTM+ CI K++ HA +RV F+T+I  +  +QEK++ M +K Y+TESMA+ +S NMD+ +++FQ+EAAISK+YASEAAW+C DEAIQ+LGGMGYMKECGLE+ MRD+RIFRIFEG+NDILRLF+V  GM + G+  K+   + +V +G+        +   L   VH  L+  A   +  I+ FG      L KH +++ N  QQ +L  +AD  + IYG+   LSRAS ++E +  SA ++  L K         + D NL D    + ++       I++ +V + G +QQ+PLGF
Sbjct:   53 AETNSFAMNIFKGDIKPSTIFPFPEVLNEEQEEMLQMLVDPCAKFFEDVNDAAANDSLEKVEDKSLEGLKEMGAFGLQVPQDLGGLGLTNTQYARLVEIVGSHDLGVGITLGAHQSIGFKGILLYGSPEQKKKYLPDLATGKKMAAFCLTEPSCGSDAAGIKTRAILSHDGTHYTLNGGKIWISNGGVADIFTVFAKTPIIDEKTGKEKDTTVAFIVERGFGGISHGAPEKKMGIKASNTAALFIDDCKVPVENMLGEVGDGFKVAMNILNNGRFGMAAALSGTMKYCINKSIEHAGQRVQFRTEISNFGAIQEKISRMVMKHYVTESMAYLVSANMDQGIKEFQIEAAISKIYASEAAWFCADEAIQVLGGMGYMKECGLERVMRDLRIFRIFEGTNDILRLFVVLTGMEYAGRALKSAGQM-SVVTGMLKRKLGMSSGDSLSTQVHESLKEPADQASKSIANFGQVITSQLIKHGRNVKNPEQQFVLNRIADAAIDIYGMVAVLSRASRSIEQNHSSAQHELELTKVFCEEAAIRI-DQNLRDTMDTKALRRYGSLAQISQDVVSNNGTLQQHPLGF 629          

Query:  152 SSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDD-----SKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLSSSFTYGYNK-----------KQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYNET------IKSIAEHLVQSEGVVQQNPLGF 1846
            +S SF L+LF G+V+  Q+ PFP VL  +Q   L  M+ P+ KFF+EVNN  KND LETIEP ++  L ++GAFGLQVP EYGG+GL+NTQYARLVE+VG YD+GVGIALGAHQSIGFKGI LYGT EQK KYLP LASGKK AAYCLTEPS+GSDA ++Q +A  S  G HY +NGSKLWISNGGI ++ TVFAKT   D     +K K+TAFIV+R FGG+S  PPEKKMGIKCSNTAAL+FE+ +IP ENVLGG GNGFKVAMN+LNNGRFGMAA LSGTMR CI KA  HA  R  F  KI  Y  +QEKLA MA K Y TESMA+ +SG MD  V +FQ EAAISKVY SEAAWYC DEAIQILGGMGYM+E GLE+ MRD+RIFRIFEG+NDILRLF    G+ + GK+ +   L ++  S  S+  + G+ K             L++ +HPEL+ S +LL       G A   ++ KH+K +I +Q  L  LA+  M  Y ++ ALSRA  ++     SA Y+  LV + L N        NL  +  N T       K I++ +  + GVVQ NPLG 
Sbjct:   48 ASDSFVLNLFSGRVNTKQLTPFPSVLDSDQRSTLAGMVEPVDKFFQEVNNADKNDALETIEPNTLTGLAEMGAFGLQVPIEYGGLGLSNTQYARLVEVVGAYDLGVGIALGAHQSIGFKGITLYGTHEQKQKYLPDLASGKKFAAYCLTEPSSGSDAGSVQTRAVLSPCGKHYKMNGSKLWISNGGIADVMTVFAKTEVKDEATGAAKDKVTAFIVERGFGGVSSGPPEKKMGIKCSNTAALYFEDTEIPVENVLGGVGNGFKVAMNVLNNGRFGMAAALSGTMRLCIAKASEHAAGRTQFGAKISSYGAIQEKLARMAAKHYATESMAYLVSGLMDSGVAEFQAEAAISKVYGSEAAWYCADEAIQILGGMGYMRETGLERVMRDLRIFRIFEGTNDILRLFFTLLGVQYAGKQLQ--QLAKSPLSNPSALVSMGFRKMGLGSVASPDTGALLERLHPELKASGELLGQTAGHLGQAVQDIVVKHKKGVIERQHELNRLAEGAMHAYAMAAALSRADQSLRAGAASAEYETRLVHY-LCNESADWIQYNLGQLKSNRTQTSIELSKDISKTVCDNGGVVQVNPLGL 631          

Query:  152 SSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDD-----SKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLSSSFTYGYNK-----------KQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYNET------IKSIAEHLVQSEGVVQQNPLGF 1846
            +S SF L+LF G+V+  Q+ PFP VL  +Q   L  M+ P+ KFF+EVNN  KND LETIEP ++  L ++GAFGLQVP EYGG+GL+NTQYARLVE+VG YD+GVGIALGAHQSIGFKGI LYGT EQK KYLP LASGKK AAYCLTEPS+GSDA ++Q +A  S  G HY +NGSKLWISNGGI ++ TVFAKT   D     +K K+TAFIV+R FGG+S  PPEKKMGIKCSNTAAL+FE+ +IP ENVLGG GNGFKVAMN+LNNGRFGMAA LSGTMR CI KA  HA  R  F  KI  Y  +QEKLA MA K Y TESMA+ +SG MD  V +FQ EAAISKVY SEAAWYC DEAIQILGGMGYM+E GLE+ MRD+RIFRIFEG+NDILRLF    G+ + GK+ +   L ++  S  S+  + G+ K             L++ +HPEL+ S +LL       G A   ++ KH+K +I +Q  L  LA+  M  Y ++ ALSRA  ++     SA Y+  LV + L N        NL  +  N T       K I++ +  + GVVQ NPLG 
Sbjct:   23 ASDSFVLNLFSGRVNTKQLTPFPSVLDSDQRSTLAGMVEPVDKFFQEVNNADKNDALETIEPNTLTGLAEMGAFGLQVPIEYGGLGLSNTQYARLVEVVGAYDLGVGIALGAHQSIGFKGITLYGTHEQKQKYLPDLASGKKFAAYCLTEPSSGSDAGSVQTRAVLSPCGKHYKMNGSKLWISNGGIADVMTVFAKTEVKDEATGAAKDKVTAFIVERGFGGVSSGPPEKKMGIKCSNTAALYFEDTEIPVENVLGGVGNGFKVAMNVLNNGRFGMAAALSGTMRLCIAKASEHAAGRTQFGAKISSYGAIQEKLARMAAKHYATESMAYLVSGLMDSGVAEFQAEAAISKVYGSEAAWYCADEAIQILGGMGYMRETGLERVMRDLRIFRIFEGTNDILRLFFTLLGVQYAGKQLQ--QLAKSPLSNPSALVSMGFRKMGLGSVASPDTGALLERLHPELKASGELLGQTAGHLGQAVQDIVVKHKKGVIERQHELNRLAEGAMHAYAMAAALSRADQSLRAGAASAEYETRLVHY-LCNESADWIQYNLGQLKSNRTQTSIELSKDISKTVCDNGGVVQVNPLGL 606          

Query:  140 SDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLSSS--FTYGYNKKQLIKS------------VHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYNETIK------SIAEHLVQSEGVVQQNPLGF 1846
            S+   S+SF ++LF G ++  Q+FPFP+VL+++Q++ L+  + P  KFFEEVN+PAKND LE +EP+S++ L +LGAFGLQV ++ GG+GLNNTQYARLVEIVG +D+GVGI LGAHQSIGFKGILL+GT EQKAKYLP + +GK+ AA+CLTEPS+GSDA +I+++A  SADG HYILNGSK+WISNGG+ EI TVFA+T   D KT     K+TAFIV+R FGG++  PPEKKMGIK SNTA +++E+ KIP ENVLGG G GFKVAMNILNNGRFGMAA L+GTMR+  +KAV HA  R+ F  +I  +  +QEKLA M+  QY+TESMA+ ISGNMD    DF +EAAISKV+ASEAAW   DEAIQILGGMG+MKECGLE+ MRD+RIFRIFEG+NDILRLF+   G+   G   +    LQ  F   +++    +G   K+ I+S            VHP L  +A L A  I  FG A    L K+ + ++ +Q +L  LA+  +  Y ++V LSRA+MA+++  PSA  Q  + K   S     V + NL  I  ++T++      +IA+++ ++ G++  NPL F
Sbjct:   43 SEAKESQSFTMNLFRGVMETAQVFPFPQVLNEDQKDTLKMFVDPTAKFFEEVNDPAKNDTLEAVEPQSLEGLWELGAFGLQVSQDLGGLGLNNTQYARLVEIVGAHDLGVGITLGAHQSIGFKGILLFGTPEQKAKYLPRVTTGKEFAAFCLTEPSSGSDAGSIRSRAVLSADGKHYILNGSKIWISNGGLAEIMTVFAQTPVLDEKTGKEHDKVTAFIVERSFGGVTSGPPEKKMGIKASNTAEVYYEDVKIPVENVLGGVGQGFKVAMNILNNGRFGMAACLAGTMRAVTRKAVDHATTRLQFGRRIDSFGTIQEKLARMSTLQYVTESMAYMISGNMDSGSTDFHLEAAISKVFASEAAWTVTDEAIQILGGMGFMKECGLERVMRDLRIFRIFEGTNDILRLFVALTGIQFAGAHLRE---LQKAFKNPAANLGLIFGEATKRAIRSVGLSSPPSLSQHVHPNLVPAAALAAKSIESFGQAVEATLLKYGRGVVEEQFVLNRLANAAIDTYTMAVVLSRATMALQSGLPSAHIQELMTKVWCSEASGRVAE-NLGAIRSSQTLENFSNLSAIAKNVCENGGLIHINPLNF 632          

Query:  155 SKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSG---LSSSFTYGYNKK-------QLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVK-FALSNVRRYVTDLNLVDIHYNETI----KSIAEHLVQSEGVVQQNPLG 1843
            S+SFA+++F G++  TQ+FPFP VL+++Q   L++++ P+ KFFEEVN+PAKND LE +E  +++ LK+LGAFGLQV  E GG+GLNNTQYARLVEIVG +D+GVGI LGAHQSIGFKGILL+G K+QK KYLP LASG+ +AA+CLTEP++GSDA +I+  A  S+ G +Y +NGSK+WISN G+ EIFTVFAKT   D KT     KITAFIV+R FGG++H PPEKKMGIK SNTA L+FEN ++PAENVLG  G GFKVAMNILNNGRFGMAA LSGTM+  I KAV HA  R  F  KI  Y ++QEK+A MA+ QY+TESMA+ +SGNMD    DFQ+EAAISK++ASEAAW   DE IQI+GGMG+MK+ G+E+ +RD+RIFRIFEG+NDILRLF+   G  + G + K+    L+N       L+   T    +K        L  S+HPEL +S  L    I  FG+   ++L KH K II++Q +L  +AD  + +Y + V LSRAS ++     SA ++  L + + +    R + D+  +    ++ I    ++I+  +V++  VV  +PLG
Sbjct:   75 SQSFAVNMFKGQISTTQVFPFPSVLNEDQSTFLRELVGPVSKFFEEVNDPAKNDTLEKVEDHTLEGLKELGAFGLQVSTELGGVGLNNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGNKQQKEKYLPKLASGETVAAFCLTEPASGSDAASIRTTAVPSSCGKYYTMNGSKIWISNAGLAEIFTVFAKTPVKDEKTGEVKDKITAFIVERSFGGVTHGPPEKKMGIKASNTAELYFENVRVPAENVLGEVGGGFKVAMNILNNGRFGMAAALSGTMKGVIAKAVDHAANRTQFGNKIHNYGVIQEKMARMAMLQYVTESMAYMVSGNMDSGATDFQIEAAISKIFASEAAWLVTDECIQIMGGMGFMKDAGVERVLRDLRIFRIFEGTNDILRLFVALNGFQNAGNQLKSLQKALKNPLGNAGLLAGEITKRAKRKAGLSTGLSLQGSIHPELAHSGDLTVKAIEQFGIVIEELLLKHGKKIIDEQFVLHRVADCAIDLYAMVVVLSRASRSLSQGHSSAQHEKMLCETWCIEAHDRIMRDIKFLKSGSSKQIFKNLRAISSAVVENGTVVAPHPLG 658          

Query:  176 LFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDII---NQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVK-FALSNVRRYVTDLNLVDIHYNETI----KSIAEHLVQSEGVVQQNPLG 1843
            +F G++  TQ+FPFP VL+++Q   L++++ P+ KFFEEVN+PAKND LE +E  +++ LK+LGAFGLQV  E GG+GLNNTQYARLVEIVG +D+GVGI LGAHQSIGFKGILL+G K+QK KYLP LASG+ +AA+CLTEP++GSDA +I+  A  S+ G +Y +NGSK+WISN G+ EIFTVFAKT   D KT     KITAFIV+R FGG++H PPEKKMGIK SNTA L+FEN ++PAENVLG  G GFKVAMNILNNGRFGMAA LSGTM+  I KAV HA  R  F  KI  Y ++QEK+A MA+ QY+TESMA+ +SGNMD    DFQ+EAAISK++ASEAAW   DE IQI+GGMG+MK+ G+E+ +RD+RIFRIFEG+NDILRLF+   G  + G + K+    L+N             N   L   +    +++ ++  L +SL         + +    +   ++Q +L  +AD  + +Y + V LSRAS ++     SA ++  L + + +    R + D+  +    ++ I    ++I+  +V++  VV  +PLG
Sbjct:    1 MFKGQISTTQVFPFPSVLNEDQSTFLRELVGPVSKFFEEVNDPAKNDTLEKVEDHTLEGLKELGAFGLQVSTELGGVGLNNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGNKQQKEKYLPKLASGETVAAFCLTEPASGSDAASIRTTAVPSSCGKYYTMNGSKIWISNAGLAEIFTVFAKTPVKDEKTGEVKDKITAFIVERSFGGVTHGPPEKKMGIKASNTAELYFENVRVPAENVLGEVGGGFKVAMNILNNGRFGMAAALSGTMKGVIAKAVDHAANRTQFGNKIHNYGVIQEKMARMAMLQYVTESMAYMVSGNMDSGATDFQIEAAISKIFASEAAWLVTDECIQIMGGMGFMKDAGVERVLRDLRIFRIFEGTNDILRLFVALNGFQNAGNQLKSLQKALKNPLG----------NAGLLAGEITKRAKSAWQISFLILSLMACQIQLPYQINHLTYVCFADEQFVLHRVADCAIDLYAMVVVLSRASRSLSQGHSSAQHEKMLCETWCIEAHDRIMRDIKFLKSGSSKQIFKNLRAISSAVVENGTVVAPHPLG 560          

Query:  152 SSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDD----SKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRK-VQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLG-------KKYKNNNL-------LQNVFSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRA----SMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYN-ETIKSIAEHLVQSEGVVQQNPL 1840
            SS ++A  LF GKV+  ++FP+P++ S E+ + + Q +PP+ KFF E  +  K DE   I P++M  LK LG FG+Q+PEEYGG+GL+NT +ARL EI+ + D  + + L AHQSIG KGILL GT+EQKAKYLP LASG+ IAA+CLTEP +GSDA +IQ +A  + DG H++LNGSK+WISNGGI EI TVFA+T   D     K KITAFIV++ FGG+S   PE K+GI+ SNT  + FE+ K+P ENV+G  G+GFK+A+NILN+GRF M    +G ++  I+    +A  R  F  K+ E+ M+QEK A MA   Y+ ESMA+  +G MDR  V D  +EAA+ K+++SE AW C  EA+Q+LGG+GY K    E+ +RD RI +IFEG+N+ILR+F+   GM H G       K+ K  N+        Q +   L  +  +G   K  +  VHP L  SA +    +  F      +L ++ K I+++QL+LK +AD ++ +Y ++  LSRA    S+ + N +          K A   +  +   L       N + IK IA+ +++       +PL
Sbjct:   41 SSAAYAKDLFLGKVNQKEVFPYPEI-SNEELQEINQFVPPVEKFFSEEVDSKKIDEEAFIPPETMDGLKALGLFGIQIPEEYGGLGLSNTMFARLGEII-SMDGAITVTLAAHQSIGLKGILLAGTEEQKAKYLPRLASGEHIAAFCLTEPGSGSDAASIQCRAKLTEDGKHFLLNGSKIWISNGGIAEIMTVFARTEVVDKDGQKKDKITAFIVEKAFGGVSCGKPEDKLGIRGSNTCEVTFEDTKVPVENVIGQVGDGFKIAVNILNSGRFSMGTAGAGMIKRLIEMTAEYAGTRKQFNRKLSEFGMIQEKFALMAQYAYVMESMAYLTAGIMDRPGVPDCSLEAAMVKIFSSEGAWICTSEALQVLGGLGYTKNYPYERYLRDCRILQIFEGTNEILRMFVALTGMQHAGKIITGKIKEMKKGNVGTVFEFCKQKIMENLGKTANFGLTGKDGV--VHPSLAESATMFEENVVEFSSIVESLLYRYGKTIVDEQLLLKRVADILIHLYAMTAVLSRASRSISIGLRNHDHEVLLANNFCKDAYFKINYWTAQLQRHSPENNDDNIKKIAQFVLEKRAYTCSHPL 623          

Query:  152 SSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDD----SKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRK-VQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLG-------KKYKNNNL-------LQNVFSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRA----SMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYN-ETIKSIAEHLVQSEGVVQQNPL 1840
            SS ++A  LF GKV+  ++FP+P++ S E+ + + Q +PP+ KFF E  +  K DE   I P++M  LK LG FG+Q+PEEYGG+GL+NT +ARL EI+ + D  + + L AHQSIG KGILL GT+EQKAKYLP LASG+ IAA+CLTEP +GSDA +IQ +A  + DG H++LNGSK+WISNGGI EI TVFA+T   D     K KITAFIV++ FGG+S   PE K+GI+ SNT  + FE+ K+P ENV+G  G+GFK+A+NILN+GRF M    +G ++  I+    +A  R  F  K+ E+ M+QEK A MA   Y+ ESMA+  +G MDR  V D  +EAA+ K+++SE AW C  EA+Q+LGG+GY K    E+ +RD RI +IFEG+N+ILR+F+   GM H G       K+ K  N+        Q +   L  +  +G   K  +  VHP L                            I+++QL+LK +AD ++ +Y ++  LSRA    S+ + N +          K A   +  +   L       N + IK IA+ +++       +PL
Sbjct:   41 SSAAYAKDLFLGKVNQKEVFPYPEI-SNEELQEINQFVPPVEKFFSEEVDSKKIDEEAFIPPETMDGLKALGLFGIQIPEEYGGLGLSNTMFARLGEII-SMDGAITVTLAAHQSIGLKGILLAGTEEQKAKYLPRLASGEHIAAFCLTEPGSGSDAASIQCRAKLTEDGKHFLLNGSKIWISNGGIAEIMTVFARTEVVDKDGQKKDKITAFIVEKAFGGVSCGKPEDKLGIRGSNTCEVTFEDTKVPVENVIGQVGDGFKIAVNILNSGRFSMGTAGAGMIKRLIEMTAEYAGTRKQFNRKLSEFGMIQEKFALMAQYAYVMESMAYLTAGIMDRPGVPDCSLEAAMVKIFSSEGAWICTSEALQVLGGLGYTKNYPYERYLRDCRILQIFEGTNEILRMFVALTGMQHAGKIITGKIKEMKKGNVGTVFEFCKQKIMENLGKTANFGLTGKDGV--VHPSLAT--------------------------IVDEQLLLKRVADILIHLYAMTAVLSRASRSISIGLRNHDHEVLLANNFCKDAYFKINYWTAQLQRHSPENNDDNIKKIAQFVLEKRAYTCSHPL 597          

Query:  146 ISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFF---EEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQ 1357
            I + K+  L++  G    TQ+   P+         L QM+    + +   E     A+ D+  T   K ++ L  +G   ++VPE  GG G++   Y+  +E +       G+    + S+    +L +G++EQK +++P   +G+K+  + L+EP  GSDA A    A +  DG  ++LNG+K WI+N        VFA T        I+AF+V     G+S    E K+GI+ S+TA +  E+C++P  N+LG  G GFK+AM  L++GR G+A+   G  ++ +  A  +A +R  F   I +   +Q KLA MA+       + +  S   D K + F  EAA++K+ ASEAA +C  +AIQ+LGGMGY+ +   E+  RD RI  I+EG+++I RL +  Q
Sbjct:    5 IKARKAVGLAVGCGARSLTQLAELPE---------LHQMMRQTCRDYADRELAPIAAQLDKSHTFPAKQVRELGAMGVMAVEVPESLGGAGMDYLAYSLAIEELSRGCASTGVIASVNNSLYLGPVLKFGSEEQKQQWIPPFTTGEKVGCFALSEPGNGSDAGAASTVARQ--DGGEWVLNGTKAWITNCWDASASVVFATTDKSLKHKGISAFLVPMPHPGLSLGKKEDKLGIRASSTANIILEDCRVPLGNLLGERGMGFKIAMQTLDSGRIGIASQALGIAQAALDCAADYAHKRTAFGAPIAKMQAIQFKLADMAVALESARLLTWKASMLRDAK-KPFSKEAAMAKLAASEAATFCSHQAIQVLGGMGYVTDMPAERHYRDARITEIYEGTSEIQRLVIANQ 399          

Query:  155 SKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWI 697
            SKSFA S+F G++   Q+ P+P  L++EQ + LQ+++ P+ KFFEEVNNPA ND LE +E  +MQ LK++GAFGLQVP E GG+GL NTQYARLV+IVG +D+GVGI LGAHQSIGFKGILL+G  EQK KYLP LASG+ IAAYCLTEP++GSDA +I+ +A +SA G +Y LNGSK+WI
Sbjct:    1 SKSFAASIFKGELSMHQVLPYPNALNEEQSQFLQELVDPVSKFFEEVNNPAANDTLEKVEDVTMQGLKEMGAFGLQVPTELGGLGLTNTQYARLVDIVGQHDLGVGITLGAHQSIGFKGILLFGNPEQKKKYLPKLASGELIAAYCLTEPASGSDAASIKTRAVRSACGKYYTLNGSKIWI 181          

Query:  353 LKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLV 1351
            + +LG   + VPE+YGG GL+   Y   +E +       G+ +  + S+    +L YG+   K K++PS   G+KI  + L+EP  GSDA A    A    DG  +++NG+K WI+N        VFA T        I+AF++     G+S    E K+GI+ S+TA L FE+C+IP ++++G  G GFK+AM  L++GR G+A    G  ++ +  AV +A +R  F   I +   +Q KL+ MAL       + +  +   D   +++  EAA++K+ ASEAA +   ++IQILGGMGY+ +   E+  RD RI  I+EG+++I RL + 
Sbjct:   76 MGELGLLAMAVPEQYGGAGLDTLAYVIALEEISRGCASTGVIMSVNNSLFLGPVLKYGSDAIKEKWIPSFTDGQKIGCFGLSEPGNGSDAGAASTTA--RVDGDSWVINGTKAWITNAWDASATVVFATTDKSLKHKGISAFVLPMPCPGLSLGKKEDKLGIRASSTANLIFEDCRIPRDSMVGEPGMGFKIAMQTLDSGRIGIAGQALGIGQAALDCAVEYASKRQAFGKSITKLQAIQFKLSDMALALESARLLTWRAAMLKDNG-KNYTKEAAMAKLAASEAATFISHQSIQILGGMGYVTDMPAERHYRDARITEIYEGTSEIQRLVIA 405          

Query:  230 SKEQEENLQQMIPPIVKFFEEVNNP--AKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDI 1333
            S  +EE +  M   + KF  +   P  A+ D    +    +  L + G  G+++    GG G         VE +   D  V +      ++    +   GT EQ+  YLP LAS   + ++CL+E  +GSDA A++ +A+K  D  H++LNG+K+WISN     +F V A    +     IT F+V+R+  G+     E K+GI+ S+T  + FEN K+P   VLG EG+G+K A+ +LN GR G+AA + G  + C   AV +  +R  F  +I ++  +Q ++A +A +      + +  +  +      F  +A ++K + SE A     + ++ +GG+G+     +EK  RD ++  + EG+++I
Sbjct:    8 SLNEEEAM--MRDAVAKFARDKLAPIVAEMDRASVMHQGVIDGLFEQGLMGIEIDVALGGAGSTFFASVLAVEELARVDPSVAVLCDIQNTLINTMVRKLGTAEQQGHYLPRLAS-DTVGSFCLSEEGSGSDAFAMKMRAEKRGD--HFLLNGTKMWISNAEHAGVFLVMANAAPERGYKGITCFVVERDTPGLQVGKKEDKLGIRASSTCPVHFENVKVPLSAVLGQEGHGYKYAIGMLNEGRIGIAAQMVGLSQGCFDHAVAYTKQRKQFGQRIYDFQGMQHQIAHVATQIEAARLLTYN-AARLREAGLPFLTQACMAKYFTSEVASLTTSKCMEWMGGVGFTTSYPIEKYYRDCKVGTVPEGTSNI 371          

Query: 1010 VVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQG-------MIHLGKKYKN-----NNLLQNVFSGLSSSFTYGYNKKQLIK-SVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQ 1582
            + HA  R  F +KI  Y  +QEK+A M + QY TE+MA+ IS NMD    +FQ+EAAISKV+ASEAAW   DE  QILGGMG+MK+CG+E+ MRD+RIFRIFEG+NDILRLF+   G       +  L K  KN       ++  V  G  +  + G      +K SVHP+L +S +L+A  +  FG +   +L KH K I+ +
Sbjct:    2 IEHAANRTQFGSKIHTYGTIQEKIARMIMLQYTTEAMAYMISANMDSGATEFQIEAAISKVFASEAAWKVTDEC-QILGGMGFMKDCGVERVMRDLRIFRIFEGTNDILRLFVALTGIQVSTNSLAMLQKALKNPIGNFGTIMGEV--GKRARRSVGLGSGLTLKGSVHPKLESSGELVAKGVDQFGASVEGLLLKHGKKIVGE 202          

Query:  353 LKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITE-SMAFAISGNMDR-KVQDFQVEAAIS--KVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFL 1348
            + ++G  G  +   YG  G+++  Y  +   V   D G    +    S+    I  YG+++Q+ KYLP LA G+ +  + LTEP+ GSD   ++ +A  +A G+ Y L G+K WI+N  I ++F V+AKT  D    ++  F+++R   G+S      K  ++ S T  +  E+ ++PAEN+L G  +G       LNN RFG+A G  G    C   A  + M+R+ F   +    +VQ+KLA M     +TE S+       + R K Q       IS  K  +   +      A  +LGG G   E  + + + ++     +EG++DI  L L
Sbjct:  104 MGEMGVLGPTIKAGYGCAGVSSVAYGLIAREVERVDSGYRSVMSVQSSLVMHPIHAYGSEQQRLKYLPRLAKGEIVGCFGLTEPNHGSDPGGMETRARYNASGNTYTLTGTKTWITNSPIADVFVVWAKTQEDG---RVRGFVLERGMAGLSAPKINGKFSLRASVT-GIVMEDVEVPAENLLPGV-SGLAGPFGCLNNARFGIAWGALGAAEFCFHTARQYTMDRMQFGVPLARNQLVQKKLADM-----LTEISLGLQACVQLGRLKDQGLAAPEMISMLKRNSCGKSLDIARTARDMLGGNGIADEYHVIRHVLNLEAVNTYEGTHDIHALIL 429          

Query:  425 YARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASG--KKI-AAYCLTEPSAGSDAQAIQAKADKSADGSHYI-----LNGSKLWISNGGIGEIFT---VFAKTMGDDSKTKITAFIVD-------REFGGISHSPPEKKMGIKCSNTAALFFENCKIPAE-------NVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKK----------AVVHAMERVTF-------KTKIIEYAMVQEKLATMALKQYITESMAFAISGN----------------------MDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRL 1342
            + + + +V   D  +G  +G H  +    I   GT EQ   +L    +   K I   + +TE   GS+   +Q +A        ++     L  +K WI  GG     T   V+A+ + +     +  F+V        +   G+S      KMG    +   + F N  IP E        V+        V      +   G +A LSG +   +            AV +A+ R  F       +T++I+Y + Q ++       Y+   +AF +  N                      + +K+++  +++A  K   +      +DE  Q  GG GY +  G  K   D  +   +EG N++L L
Sbjct:  129 FDKRLSLVANIDPQLGTRVGVHLGLFGNCIKGNGTDEQIRYWLQERGATLMKGIYGCFAMTELGHGSNVAQLQTRAVYDKQNDTFVIDTPDLTATKWWI--GGAAHSATHAAVYARLIVEGKDYGVKTFVVPLRDPSTFQLLAGVSIGDIGAKMGRDGIDNGWIQFRNVVIPREFMLSRFTKVVRSPDGSVTVKTEPQLDQISGYSALLSGRVNMVMDSFRFGSKFATIAVRYAVGRQQFAPRKGLSETQLIDYPLHQYRVLPQLCVPYLVSPVAFKLMDNYYSTLDELYNASSSAYKAALVTVSKKLKNLFIDSASLKATNTWLIATLIDELRQTCGGHGYSQYNGFGKGYDDWVVQCTWEGDNNVLSL 496          

Query:  170 LSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSGLSSSFTYGYNKKQ----------LIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVK-FALSNVRRYVTDL-NLVD---IHYNETIKSIAEHLVQSEGVVQQNPLGF 1846
            ++LF+GK++  Q+FPFP+VL+++QEE L+  + P+ KFFEEVN+PAKNDELET+E   M+ LK++GAFGLQVP + GG+GL NTQYAR+VEIVG +D+ VGI LGAHQSIGFKGILL+G KEQK KYLP +A+GKK AA+CLTEPS+GSDA +I+ +A+ S DG H+ILNG KLWISNGGI +IFTVFAKT   D KT     K+TAFIV+R FGG+   PPEKKMGIK SNTA ++F+N  +P ENVLGGEGNGFKVAMNILNNGRFGMA  LSGTM+  I+KAV  A  R  F  KI  +  +QEK+A MA+  Y+TESMA+ IS NMD    DFQVEAAISKV+ASEAAW+  DE IQILGG G+MK  G+E+ MRD+RIFRIFEG+NDILRL +   G+   GK+ +     L+N    + +   +G  + +          L + VH +L+ SA  ++  +  FG A   +L K+ K ++ QQ +LK LAD  M +YG+   LSRAS ++     ++ ++  + + F      R   +L +L D   +  ++T+  IA  +V+++ VV ++PLGF
Sbjct:    1 MALFNGKLEPEQVFPFPEVLTQDQEEELRAFVEPVSKFFEEVNDPAKNDELETVEEHVMESLKEMGAFGLQVPADLGGVGLTNTQYARMVEIVGAHDLAVGIVLGAHQSIGFKGILLFGNKEQKEKYLPQVATGKKYAAFCLTEPSSGSDAASIKTRAELSKDGKHWILNGGKLWISNGGIADIFTVFAKTPIKDPKTGEVKDKVTAFIVERGFGGVESGPPEKKMGIKASNTAEVYFDNVPVPVENVLGGEGNGFKVAMNILNNGRFGMAGALSGTMKGLIEKAVDFAANRTQFGAKIETFGAIQEKIARMAMLHYVTESMAYMISANMDSGATDFQVEAAISKVFASEAAWFVADECIQILGGTGFMKSAGVERVMRDLRIFRIFEGTNDILRLMIALTGLQGAGKRLQALQKQLKNPVGNIGALMDFGLGRTKRALGMNTGPSLTEHVHKDLQPSADQVSKAMGDFGGAVEGLLMKYGKKVLEQQFLLKRLADATMDLYGMVAILSRASRSLNRGSETSQHEAMICQVFCSEAADRIARNLRSLQDPQSLSNDKTMSRIAGEVVRNQRVVPEHPLGF 580          

Query:  353 LKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTK--ITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFL 1348
            L DLG  G+ VP + GGIG    ++  ++E +      + ++ GAH ++    I   G KEQK KYLP L SG+ I A  ++E +AGSD  +++ +ADK  DG HY+LNG K+WI+NG   ++  V+AKT     K +  IT F+V++   G S SP   K+G++ SNT  L F+NC+IPAENV+G    G  V M+ L+  R  +AAG  G M++C+   V +   R  F  KI E+ M+Q K+A M  +     S  + ++   D      +  AAI  +Y +E A     +AIQ LGG GY+ +    + +RD +++ I  G++++ RL +
Sbjct:   83 LGDLGFHGITVPVDDGGIGSGYMEHIIVLEEMSRVSGSIALSYGAHSNLCINQIARNGNKEQKRKYLPKLLSGEHIGALAMSEANAGSDVVSMKLRADK--DGDHYVLNGHKMWITNGPDADVLIVYAKTNPSSKKPEHAITTFLVEKGMPGFSTSPKLDKLGMRGSNTCELVFDNCRIPAENVMGEVNKGVYVLMSGLDIERLILAAGPVGLMQACLDVTVPYLHARTAFGQKIGEFQMMQGKMADMYTRLNACRSYLYTVARACDAGHISNKDCAAII-LYTAENATQVALDAIQCLGGNGYINDYPTGRFLRDAKLYEIGAGTSEVRRLII 413          

Query:  257 QMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQ 1357
            ++ P   KF +E   P +           ++ L +LG  G++VPE  GG GL+   YA  +E +      +G  +  + S+    IL YGT  QK +++    +G ++  + L+EP  GSDA A  AK     DG HY+LNG+K WI+NG   E   VFA T        I+AF+V +   G++    E K+GI+ ++T  L FE+C+IP EN+LG  G GFK+AM  L+ GR G+A    G  ++ +  AV +A +R+ F  KI +   +Q KLA +A +      + +  +   D  + ++  EAA++K+ ASEAA +   ++IQILGGMGY+ +   E+  RD RI  I+EG+++I +L +  +
Sbjct:   59 ELTPVAGKFDKEHRYPQEK----------VKMLGELGLLGVEVPESLGGTGLDAFAYAIAMEEISRGCASLGCIMSVNNSLYLGPILKYGTDAQKEEWIKPFLNGDRVGCFALSEPDNGSDAGA--AKTTAVLDGDHYVLNGTKAWITNGYESEAAVVFATTDRSKKHKGISAFLVPKPTPGLTLGNKEDKLGIRATSTCYLVFEDCRIPKENLLGEPGYGFKIAMQTLDAGRIGIAGQALGIAQAALDCAVDYADKRMAFNQKISKLQTIQMKLADIATQLEAARLLTWKAAAIKDAGM-NYTKEAAMAKLAASEAATFAAHQSIQILGGMGYVTDMPAERHYRDARITEIYEGTSEIQKLVIAGR 412          

Query:  215 FPKVLSKEQEENLQQMIPPIVKFFEEVNNP--AKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTK-ITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMAL----KQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEA--IQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGK 1378
            F   LS    + L+ +     KF  E   P  A++D+      + ++   ++G     +PE YGGIGL       + E +     G+  A+ A+ S+    ++L G +EQK KYL  +     +AAYC+TEP+AGSD   I+ +A+K  D   Y++NG K+WI+NGG+   + V A+T    S  K  T FIVD +  G++    E+ MG + S+T  + FE+  +P ENVLG EG GFK+AM   +  R  +A+   G  R  +++A  ++MER T    I E+  VQ  LA MA+     +  T+  A+ I  +  R+   +   A+I+K  A + A  C      + I GG G+ +E  +EK MRD +IF+I+EG+  I R+ ++ + +I   K
Sbjct:    2 FAYFLSLAMSDELRALQDMARKFAREEIMPKAAEHDKTGEYPWEIIKKAHEVGLVNGHIPEAYGGIGLGVLDGCVVTEELSYACSGIQTAIEAN-SLAEMPVILAGNEEQKKKYLGRMIKEPIMAAYCVTEPTAGSDVAGIKTRAEKKGD--EYVINGQKMWITNGGVANWYFVLARTDSSASAGKGFTGFIVDADTPGVTPGRKEQNMGQRASDTRGITFEDVVVPKENVLGAEGIGFKIAMGAFDKTRPPVASSAVGLARRALEEATKYSMERKTMGKYICEHQAVQFLLADMAIGVETARLATQRSAWEI--DQGRRNTYY---ASIAKCLAGDVANKCTTRWTDLGIFGGNGFNQEYPVEKLMRDAKIFQIYEGTAQIQRM-IIGRSLIEAAK 389          

Query:  218 PKVLSKEQEENLQQMIPPIVKFFEEVNNP--AKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYAR--LVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCK-IPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIE---YAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQV--EAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDI 1333
            P     E+EE ++Q    + +F +E   P  ++ D+   ++P  ++ L + G  G+++  EYGG   ++T +A   ++E +   D  V +      ++    I+ YGTKEQK +YLP LA    +  +CL+E S+GSDA A++  A +  DG H++LNGSK+WI+N     +F V A     +    IT FIV RE  G+S    E K+GI+ S+T  + F+N K +P+ +VLG  G+G+K A+ +LN GR G+ A + G  + C    V +  ER  F   I     +AM Q ++A +  K    E+    +     RK     V  E A++K +ASE A     + ++ +GG+G+ K   +EK  RD +I  I+EG+ +I
Sbjct:    4 PLTQLSEEEEMMKQ---SVARFAKEKIQPLVSEMDQNSQMDPGIIKGLFEQGLMGIEIGSEYGGT--DSTFFAANLVIEELAKVDPSVSVMCDVQNTLINNLIMTYGTKEQKQEYLPQLAQ-HMVGGFCLSEESSGSDAFALKTVALEK-DG-HFVLNGSKMWITNAEYAGVFLVMANVNPSEGYKGITTFIVPRETPGLSIGKKEDKLGIRASSTCPVHFDNVKVVPSSSVLGEVGHGYKYAIGMLNEGRIGIGAQMLGLAQGCFDHTVPYTHERRQFGRSIWSNQAWAM-QHQIAEVRTK---IEAARLLVYNAARRKEAGLPVVREGAMAKYFASEVATLTTSKCMEWMGGVGFTKSYPIEKYYRDCKIGTIYEGTTNI 373          

Query:  128 VRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKT-----KITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKN-NNLLQNVFSG---LSSSFTYGYNKK-------QLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVK-FALSNVRRYVTDLNLVDIHYN----ETIKSIAEHLVQSEGVVQQNPLGF 1846
            V + S  + SKSFA+++F G++  +Q+FPFPK L++EQE+ L++++ P+ KFFEEVN+PAKND LE +E  +M+ LK++GAFGLQVP + GG+GL+NTQYARLVEIVG++D+GVGI LGAHQSIGFKGILL+G K QK KYLP LA+G+ IAA+CLTEP++GSDA +I+  A  S  G +Y + GSK+WISNGG+ EIFTVFAKT   D +T     KITAFIV+R FGG+SH PPEKKMGIK SNTA ++F+N ++PA+ VLG  G GFKVAMNILNNGRFGMAA LSGTM+  I KAV HA  R  F  KI  Y  +QEK+A MA+  Y+TESMA+ ISGNMD    +FQ+EAAISK++ASEAAW   DE+IQ++GGMG+MK+ G+E+ MRD+RIFRIFEG+NDILRLF+   G  + G   K+    L+N       L+   T    +K        L  SVHPEL  S  L    I  FG    ++L KH K II++Q +LK +AD  + +Y + V LSRAS ++     SA ++  L + + L    R + D+  +    +    + +++I+  +V++ GVV  +PLGF
Sbjct:   63 VEKKSVTAESKSFAVNMFKGQIATSQVFPFPKALNEEQEQFLRELVGPVCKFFEEVNDPAKNDALEKVEDHTMEGLKEMGAFGLQVPGDLGGLGLSNTQYARLVEIVGSHDLGVGITLGAHQSIGFKGILLFGNKAQKEKYLPKLATGENIAAFCLTEPASGSDAASIKTTAVLSPCGQYYTMTGSKIWISNGGLAEIFTVFAKTPVKDPQTGEVKDKITAFIVERSFGGVSHGPPEKKMGIKASNTAEVYFDNVRVPADCVLGEVGGGFKVAMNILNNGRFGMAAALSGTMKGVISKAVDHAANRTQFGNKIHTYGAIQEKVARMAMLHYVTESMAYMISGNMDSGAAEFQIEAAISKIFASEAAWTVTDESIQVMGGMGFMKDSGVERVMRDLRIFRIFEGTNDILRLFVALNGFQNAGNHLKSLQKALKNPIGNAGLLAGEITKRAKRKAGFSSGLTLQGSVHPELAQSGDLTVKAIEEFGAVIEELLVKHGKKIIDEQFVLKRVADCAIDLYAMVVVLSRASRSLSQGAASAQHEKMLCETWCLEAYDRILHDIKFLRSGQSKQTFKNMRAISAAMVENGGVVSPHPLGF 656          

Query:  131 RRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKT---MGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRK-VQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLG-------KKYKNNNL----------LQNVFSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRA----SMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYNET-IKSIAEHLVQSEGVVQQNPL 1840
            R +   S S ++A  LF G+V+  ++FP+P++ S E+ E L Q + P+ KFF E  + A  D+   I  ++M+ LK+LG FG+ VPEEYGG+GL+NT YARL EI+   D  + + L AHQ+IG KGILL GT+ QK KYLP LASG+ +AA+CLTEP +GSDA +IQ +A  S DG HY++NGSK WISNGG+ +I TVFA+T   +    K KI+AFIV+R FGGI+   PE K+GI+ SNT  + F+N  +P ENV+G  G GFK+AMNILN+GRF M +  +G ++  I+ A  +A  R  F   + E+ ++QEK A MA+  ++ ESMA+  +G MDR  V D  +EAA+ KV++SE  W CV EA+Q+LGG+GY K    E+ +RD RI  IFEG+N+ILR+++   GM H G       K+ K  N+          ++N + G   S   G   K  +  VHP L  SAK     + LFG     +L ++ K I+++QLILK +AD ++ +Y ++  LSRA    S+ + N +       T    A      ++  L       N+  IK IA++++Q+   +  +PL
Sbjct:   35 RSFKTHSRSLAYAKDLFLGQVNKAEVFPYPEI-SNEELEELNQFVAPVEKFFSEEVDSAMIDQEARIPAETMKGLKELGLFGIMVPEEYGGLGLSNTTYARLNEII-ALDGSIAVTLAAHQAIGLKGILLAGTEAQKKKYLPKLASGEHVAAFCLTEPGSGSDAASIQTRATLSEDGKHYLINGSKFWISNGGMADIMTVFARTEVEVDGVKKDKISAFIVERAFGGITSGKPEDKLGIRGSNTCEVSFDNVPVPVENVIGEIGGGFKIAMNILNSGRFSMGSSCAGMIKKLIEMASEYAATRKQFNKSLSEFGLIQEKFALMAINAFVMESMAYLTAGMMDRPGVPDCSLEAAMVKVFSSEGGWICVSEALQVLGGLGYTKNYPYERFVRDCRILPIFEGTNEILRMYVALTGMQHAGKVLTGKIKEMKKGNIGTVMGMFGKKMRNFYGG---SVDLGLTGKDGV--VHPSLEESAKKFEQNVHLFGTTVEGLLYRYGKTIVDEQLILKKVADVMINLYAMTAVLSRASRSISIGLRNHDHEVLLANTFCSDAYFKNNYWMVQLEKHSPENNDANIKKIAQNVLQNRAYICSHPL 623          

Query:  254 QQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFG---LQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTK---ITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQ 1357
            +++IP   K   E   PA             Q +++LGA G   ++VPEE GG G++   Y+  +E +       G+ +  + S+    +L +GT+EQK K++    +G+K+  + L+EP  GSDA A    A +  +G  ++LNG+K WI+N        VFA T   D K K   I+AF+V     G+S    E K+GI+ S+TA +  E C++P +++LG  G GFK+AM  L++GR G+AA   G  ++ +  A  +A +R  F   I +   VQ KLA M +       + +  +   D K + F  EAA++K+ ASEAA +C  +AIQILGGMGY+ +   E+  RD RI  I+EG+++I RL +  Q
Sbjct:   44 RELIPVASKLDREHAYPA-------------QQIRELGAMGVMAMEVPEELGGAGMDYLAYSVAMEEISRGCASTGVVVSVNNSLYIGPVLKFGTEEQKKKWITPFTTGEKVGCFALSEPGNGSDAGAASTTARQ--EGDEWVLNGTKAWITNSWDASATVVFATT---DKKLKHKGISAFLVPMPHPGLSLGKKEDKLGIRASSTANIILEECRVPLDSMLGPRGAGFKIAMQTLDSGRIGIAAQALGIAQASLDCAADYAHKRTAFGAPIGKLQAVQFKLADMGVALESARLLTWKAALLRDSK-RPFTKEAAMAKLAASEAATFCSHQAIQILGGMGYVTDMPAERHYRDARITEIYEGTSEIQRLVIAGQ 398          

Query:  209 FPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKND-ELETIEPKSMQCLK---DLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATM-----ALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFL 1348
             P   V++   +E +Q +   + KF  E   P  +D +     P+  +  K   D+G  G+  P E GG GL    +  ++E +      + ++ GAH ++    ++ +  ++QK KY+P L SG+ + A  ++EP+AGSD  +++ +A KS D  HY+LNG+K WI+NG   ++  V+AKT     +  ITAFIV++   G S +   +K+G++ SNT  L FE+CK+P ENVLG    G  V M+ L+  R  +AAG  G M++ +  A+ +   R  F  KI  + ++Q K+A M     + +QY+         G+   K      + A   +Y +E A     + IQ LGG GY+ +  + + +RD +++ I  G++++ RL +
Sbjct:   29 IPVDDVVNGLTDEQIQ-LRQSVRKFCSEKLAPYADDIDKNNAFPEMREYWKAMGDMGLLGITAPVEEGGTGLGYLDHVIVMEEMSRVSAAIALSYGAHSNLCVNQLVRHANRQQKEKYMPKLLSGEHVGALAMSEPNAGSDVVSMKLRATKSGD--HYVLNGNKFWITNGPDADVLIVYAKTDPGAYQKGITAFIVEKGMAGFSTAQKLEKLGMRGSNTCELVFEDCKVPEENVLGPLNKGVYVMMSGLDLERLVLAAGPVGIMQAVLDNAIPYMHVREAFGQKIGHFQLMQGKMADMYTRLSSCRQYLYNVARACDRGHFSAK------DCAGVILYCAENATQVALDGIQCLGGNGYINDYPMGRFLRDAKLYEIGAGTSEVRRLII 408          

Query:  206 IFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNP--AKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDI 1333
            +  FP + +  +EE++  M   + K+ +E   P  +K DE   ++ + ++ L + G  G+++  EYGG G +      ++E +   D  V +      ++        GT  QK KYL  L++   I ++CL+E  +GSDA A++ +A+K  D   Y++NGSK+WISN     +F V A          IT FIVDRE  G+     E K+G++ S+T  + F+N K+P  N+LG  G+G+K A+ +LN GR G+AA + G  + C    V +  +RV F  +I ++  +Q ++A +A +      + +  +  +    + F  EA ++K +++E A     + I+ +GG+G+ K+  +EK  RD +I  I+EG+ +I
Sbjct:   47 VVSFPPLQTYSEEESM--MKDAVKKYAQERIAPFVSKMDEKSAMDEEVIKSLFEQGLMGIEIDPEYGGTGSSFFASILVIEELAKVDPSVSVLCDIQNTLINVLFTKLGTPAQKEKYLSHLST-DMIGSFCLSEAESGSDAFALKTRAEKHKD--FYVINGSKMWISNAEHAGVFLVMANVNPSAGYRGITCFIVDRETEGLEIGKKENKLGLRASSTCPVNFDNVKVPESNILGEIGHGYKYAIGMLNEGRIGIAAQMVGLAQGCFDHTVPYTRQRVQFGKRIFDFQGMQHQIAHVATQIEAARLLTYN-AARLKEAGRPFIKEACMAKYFSAEVATLTTSKCIEWMGGVGFTKDYPIEKYYRDCKIGTIYEGTTNI 418          

Query:   65 MKLNTLYRVLKHVHNKNFTSCVRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYNETIKSIAEHLVQSEGVVQQNPLGF 1846
            MKLNTLYRVLKHVHNKNFTSCVRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYNETIKSIAEHLVQSEGVVQQNPLGF
Sbjct:    1 MKLNTLYRVLKHVHNKNFTSCVRRYSDISSSKSFALSLFDGKVDCTQIFPFPKVLSKEQEENLQQMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLVAQGMIHLGKKYKNNNLLQNVFSGLSSSFTYGYNKKQLIKSVHPELRNSAKLLALRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSASYQCTLVKFALSNVRRYVTDLNLVDIHYNETIKSIAEHLVQSEGVVQQNPLGF 594          

Query:  257 QMIPPIVKFFEEVNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKY-LPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFLV 1351
            ++IP   +F +  N P   DE++         L +LG   L VPE  GG GL+   Y   +E +      VG+ +  + S+    +L +G +EQ  ++  P L SGK +  + L+EP+ GSDA A    A K  DG+++ILNG+K WI+NG   E   VFA T        I+ FI+ +   G+S    E K+GI+ S+T  L FE+CKIP   +LG  G GFK+AM  L+ GR G+A    G  ++ ++ AV ++ +R  F   I ++  +Q KLA MA +      + +  +   D K + F  EAA++K+ ASEAA +   ++IQILGGMGY+ +   E+  RD RI  I+EG+++I RL + 
Sbjct:   61 ELIPKAAEFDKTHNYP--KDEIKK--------LGELGLLSLIVPENKGGSGLDYLAYTIAMEEISRGCASVGVIMTVNNSLYLAPLLKHGNEEQWEQFGRPFLQSGK-VGCFALSEPANGSDAGAASTSARK--DGNNWILNGTKSWITNGYEAEAAIVFATTDKPLKHKGISTFILPKPIAGLSLGKKEDKLGIRASSTCQLIFEDCKIPGNFLLGKPGLGFKIAMQTLDGGRLGIAGQALGIAQAALECAVDYSAKRFCFSQPIAKFQAIQVKLADMATRLEAARLLTWNAARKCD-KGESFTKEAAMAKLMASEAATFVAHQSIQILGGMGYVTDMPAERHYRDARITEIYEGTSEIQRLVIA 412          

Query:  353 LKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTK--ITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLFL 1348
            L ++G  G+  P EYGG   +   +  + E +      + ++ GAH ++    I+ +G + QK KYLP L SG  I A  ++E  +GSD  +++  A K  +G +YILNG K WI+N    ++  V+A++  +  K +  I+ F+V++E  G + SP   K+G++ SNTA L F+NCK+    ++G    G  + M+ L+  R  +++G  G M++    A  +A  R  F   I EY ++Q K+A M +K     S  + ++ ++ R  ++ + + A + ++++E+A     +AIQILGG GY+ +    + +RD +++ I  G++++ RL +
Sbjct:   76 LGEMGFLGITAPYEYGGTEGSYLDHCLINEELSRASGSIALSYGAHSNLCVNQIVRHGNELQKKKYLPKLISGDFIGALAMSESGSGSDVVSMKLSARK--EGEYYILNGHKFWITNAPDADVIVVYARSDPNSEKPQHGISTFLVEKETPGFTVSPKLDKLGMRGSNTAELVFDNCKVHESQLMGMINKGVYILMSGLDYERCVLSSGPLGLMQASCDIAFDYAQHRKAFGQPISEYQLMQCKMAEMYVKLVTCRSYVYNVARSLGRGERNSR-DCAGAILHSAESATQVALDAIQILGGNGYINDYPTGRILRDAKLYEIGAGTSEVRRLLI 406          

Query:  239 QEENLQQMIPPIVKFFEEVNNP--AKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFAKTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQDFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDI 1333
            +EEN+  M   + K   E   P   K D    +E   +  L + G  G+++P  YGG   +      ++E +   D  + I +    ++    I+  GT EQK+ +LP LA    I ++ L+E ++GSDA +++  A   ADG+ +++NGSK+WISN     +F V A          IT FIV R+  G++    E K+G++ S+T  + F+N ++P  NVLG  G G++ A+ +LN GR G+AA + G  + C+   + +  ER  F  +I ++  +Q +++ +  +     +  + I+   +    + Q EA++ K  +S  A       I+ +GG+G+ K+  +EK  RD++I  I+EG+++I
Sbjct:   39 EEENM--MKETVSKLAAERIQPFVRKMDSQGYMEKSVIDGLFENGLMGIEIPSSYGGTEASFFSSILVIEELSKVDPSIAILVDIQNTLIITLIMRLGTAEQKSYWLPKLAH-NTIGSFALSEAASGSDAFSLKTVA--MADGNDFVINGSKMWISNSMEAGVFLVMANIDPSQGYKGITVFIVPRDNQGLTVGKKEDKLGLRASSTCQVHFDNVRVPRTNVLGELGQGYRYAIGMLNEGRVGIAAQMVGLSQGCLDFTIRYIRERRQFNRRIWDFQAMQHQVSEICSELECVRTFMYNIARQKESGY-NIQKEASMVKFLSSNLATKVTSRCIEWMGGVGFTKDYPVEKYYRDVKIGCIYEGTSNI 399          

Query:  293 VNNPAKNDELETIEPKSMQCLKDLGAFGLQVPEEYGGIGLNNTQYARLVEIVGTYDMGVGIALGAHQSIGFKGILLYGTKEQKAKYLPSLASGKKIAAYCLTEPSAGSDAQAIQAKADKSADGSHYILNGSKLWISNGGIGEIFTVFA---KTMGDDSKTKITAFIVDREFGGISHSPPEKKMGIKCSNTAALFFENCKIPAENVLGGEGNGFKVAMNILNNGRFGMAAGLSGTMRSCIKKAVVHAMERVTFKTKIIEYAMVQEKLATMALKQYITESMAFAISGNMDRKVQ-DFQVEAAISKVYASEAAWYCVDEAIQILGGMGYMKECGLEKTMRDMRIFRIFEGSNDILRLF-------LVAQGMIHLGKKYKNNNLLQNVFSGLSSSFTYGYNKKQLI-KSVHPELRNSAKLLA---------LRISLFGLAANQMLRKHRKDIINQQLILKSLADEVMMIYGISVALSRASMAMENSEPSAS 1690
            + N +K D L T E K M+ LK  G FG  +P+ +GG+GLN +QYA L++     D    + L AHQ++  + IL YG+ EQ+ +YLP +A G+ + A+CL+E  +G D  ++++ A        YILNG+K W+ NG   ++F VFA    +M +  +  IT FI+DR   GIS S P     +     + + F+N  I  + VL  E  G+K+A +I NN R+ +AA ++G MR  +   V      +T    ++   + Q K+   A++  +  +  FA     D  +Q + Q+E+A  KVY+ E     ++ +  I   +  +      K  + +   + F GSN   RL+       L  + ++ L K+ ++   +QNV   L S+    +N   L  K+  P ++N  + L          +RIS   +     +   + D    Q ++ ++++  ++ Y ++  ++RA+    + E +AS
Sbjct:   85 IENLSKMD-LTTYE-KGMEQLKRAGIFGALIPKRFGGLGLNLSQYAYLMQNENLIDWS--LVLIAHQNLCAEAILKYGSYEQQDRYLPKMAKGELLGAFCLSEQGSGIDMFSMESTAILQPLRDTYILNGTKNWVVNGYHADVFIVFALSRDSMEEGGRDFITGFIIDRNNFGISVSEPYDIDWLHNCKVSDVTFDNISISIDQVLSEENGGYKIAHDIQNNARYVIAASMAGIMRKVVNDLVSIESSLITPTDALVNSLIHQCKIILYAVESTLYFTTRFA-----DNYLQPEIQLESAALKVYSIERTHELLEISHNIYNLIDRLVPPEFRKYYKIINGIQNFMGSNFYNRLYIGGTVIELSNRKVMELKKRLRST--MQNV-PWLKSTLKDAFNPMLLFEKTTDPLVKNPEEYLQFIQDLRSIFMRISKTKVLLITAMNNLKHDTFEYQHLMTAMSNIGIITYTLACCIARANTTFGDFEINAS 559